# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- COX6B PF02297.12 KFO94843.1 - 1.6e-14 53.6 4.4 1.9e-14 53.3 3.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KFO94843.1 - 0.035 14.0 0.7 1.3 9.0 0.5 2.2 1 1 0 1 1 1 0 CHCH domain Toxin_3 PF00537.13 KFO94843.1 - 0.054 13.3 0.5 0.067 13.0 0.3 1.2 1 0 0 1 1 1 0 Scorpion toxin-like domain zf-C2H2 PF00096.21 KFO94844.1 - 1.2e-06 28.4 13.1 0.0011 19.1 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type XPA_N PF01286.13 KFO94844.1 - 3.6e-05 23.3 2.6 0.056 13.1 0.0 2.2 2 0 0 2 2 2 2 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFO94844.1 - 9.3e-05 22.2 4.3 0.02 14.8 0.1 2.2 2 0 0 2 2 2 2 Zinc ribbon domain zf-C2H2_4 PF13894.1 KFO94844.1 - 0.00026 21.1 10.5 0.033 14.5 0.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO94844.1 - 0.00048 20.2 1.8 0.00048 20.2 1.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFO94844.1 - 0.00058 19.6 8.2 0.058 13.3 0.3 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO94844.1 - 0.002 18.2 8.7 0.078 13.1 0.4 3.0 2 1 1 3 3 3 2 Zinc-finger double-stranded RNA-binding DNA_RNApol_7kD PF03604.8 KFO94844.1 - 0.0031 16.9 1.1 1 8.8 0.1 2.2 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit DUF2256 PF10013.4 KFO94844.1 - 0.0034 17.0 2.3 0.27 11.0 0.4 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) YhfH PF14149.1 KFO94844.1 - 0.005 16.5 2.0 1.8 8.4 0.2 2.2 2 0 0 2 2 2 2 YhfH-like protein zf-trcl PF13451.1 KFO94844.1 - 0.0059 16.2 6.1 0.3 10.7 3.9 2.1 1 1 1 2 2 2 1 Probable zinc-binding domain Ribosomal_L31 PF01197.13 KFO94844.1 - 0.0065 16.4 1.9 0.39 10.7 1.3 2.2 1 1 0 1 1 1 1 Ribosomal protein L31 TFIIS_C PF01096.13 KFO94844.1 - 0.0082 15.7 3.8 0.32 10.6 0.1 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) UPF0547 PF10571.4 KFO94844.1 - 0.016 14.8 2.2 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Prok-RING_1 PF14446.1 KFO94844.1 - 0.017 14.8 0.9 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.16 KFO94844.1 - 0.021 14.6 6.2 0.28 11.0 0.2 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-UBP PF02148.14 KFO94844.1 - 0.026 14.6 3.7 0.068 13.3 2.5 1.6 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Nudix_N_2 PF14803.1 KFO94844.1 - 0.049 13.3 1.1 7.9 6.2 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal GCC2_GCC3 PF07699.8 KFO94844.1 - 0.05 13.1 5.7 2.6 7.6 4.0 2.1 1 1 0 1 1 1 0 GCC2 and GCC3 zf-ribbon_3 PF13248.1 KFO94844.1 - 0.054 12.7 4.0 3.2 7.0 0.1 2.4 2 1 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KFO94844.1 - 0.098 11.9 3.1 2.8 7.3 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DUF329 PF03884.9 KFO94844.1 - 0.1 12.1 2.1 1.4 8.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF329) DZR PF12773.2 KFO94844.1 - 0.12 12.1 2.0 0.24 11.2 1.4 1.5 1 1 0 1 1 1 0 Double zinc ribbon LIM PF00412.17 KFO94844.1 - 0.13 12.3 4.6 3.9 7.6 3.2 2.2 1 1 0 1 1 1 0 LIM domain zf-LYAR PF08790.6 KFO94844.1 - 0.14 11.9 7.9 0.22 11.2 0.9 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_2 PF13240.1 KFO94844.1 - 0.18 11.3 8.8 1.1 8.8 0.6 2.5 2 1 0 2 2 2 0 zinc-ribbon domain DUF2321 PF10083.4 KFO94844.1 - 0.21 11.1 2.2 3.3 7.1 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Ribosomal_S27e PF01667.12 KFO94844.1 - 0.24 10.9 1.4 9.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 NinG PF05766.7 KFO94844.1 - 0.26 11.0 3.3 4.9 6.8 0.1 2.0 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein zinc_ribbon_4 PF13717.1 KFO94844.1 - 0.29 10.8 2.8 4 7.2 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-tcix PF14952.1 KFO94844.1 - 0.3 10.4 2.1 7.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding PhnA_Zn_Ribbon PF08274.7 KFO94844.1 - 0.35 10.6 4.4 7.6 6.4 0.5 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_5 PF13719.1 KFO94844.1 - 0.54 9.8 3.8 5.1 6.7 0.7 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 KFO94844.1 - 0.57 10.2 3.2 5.4 7.1 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L44 COX5B PF01215.14 KFO94844.1 - 0.87 9.2 3.1 0.95 9.1 0.2 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Vb CpXC PF14353.1 KFO94844.1 - 0.94 9.4 3.8 10 6.0 0.1 2.1 2 0 0 2 2 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.2 KFO94844.1 - 0.96 9.3 7.8 8.8 6.2 5.4 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KFO94844.1 - 1.1 8.8 7.4 1.8 8.1 0.3 2.4 2 1 0 2 2 2 0 A2L zinc ribbon domain zf-HIT PF04438.11 KFO94844.1 - 1.9 8.2 6.2 8.1 6.1 1.6 2.4 1 1 1 2 2 2 0 HIT zinc finger HNH PF01844.18 KFO94844.1 - 2.3 8.1 8.4 3.9 7.4 1.8 2.1 2 0 0 2 2 2 0 HNH endonuclease zf-Di19 PF05605.7 KFO94844.1 - 2.5 8.3 7.4 0.97 9.6 1.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.7 KFO94844.1 - 2.5 7.8 5.5 4.2 7.1 3.8 1.5 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger DUF4379 PF14311.1 KFO94844.1 - 2.9 7.7 4.6 7.3 6.4 3.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4379) C1_1 PF00130.17 KFO94844.1 - 3.6 7.3 7.3 15 5.3 5.1 2.1 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KFO94844.1 - 4.4 7.4 7.8 2.7 8.0 2.0 2.2 2 0 0 2 2 2 0 C1-like domain C1_2 PF03107.11 KFO94844.1 - 7.6 6.7 7.3 6.9e+02 0.4 5.1 2.3 1 1 0 1 1 1 0 C1 domain 7tm_4 PF13853.1 KFO94845.1 - 6.4e-25 87.6 0.9 7.2e-25 87.4 0.6 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO94845.1 - 0.047 12.8 0.4 0.053 12.6 0.3 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.22 KFO94846.1 - 4.7e-13 48.9 0.0 6.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFO94846.1 - 6.3e-09 35.2 0.1 1.1e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain zf-C2H2 PF00096.21 KFO94847.1 - 9.4e-11 41.4 10.0 4.5e-07 29.8 0.3 2.4 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94847.1 - 1.2e-08 34.6 5.6 2.5e-05 24.3 0.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO94847.1 - 1.3e-07 31.5 15.3 2.3e-07 30.7 0.3 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFO94847.1 - 0.0037 17.1 0.1 0.0037 17.1 0.1 2.0 2 1 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 KFO94847.1 - 0.021 14.9 0.4 0.17 12.0 0.3 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 KFO94847.1 - 0.027 14.0 0.1 0.36 10.4 0.1 1.9 1 1 1 2 2 2 0 GAGA factor zf-C2H2_jaz PF12171.3 KFO94847.1 - 0.049 13.7 0.0 0.049 13.7 0.0 1.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO94847.1 - 0.31 11.3 2.8 0.42 10.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING_3 PF14369.1 KFO94847.1 - 0.46 10.5 3.1 9.5 6.3 0.0 2.2 2 0 0 2 2 2 0 zinc-finger zf-H2C2_5 PF13909.1 KFO94847.1 - 2.5 8.4 6.7 5.6 7.3 0.1 2.5 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFO94848.1 - 2.3e-11 43.3 7.0 4.3e-05 23.5 2.0 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO94848.1 - 2e-08 34.1 10.3 3.6e-08 33.2 0.5 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO94848.1 - 7e-07 29.1 7.6 0.0052 17.0 1.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO94848.1 - 1.5e-05 24.7 6.2 0.012 15.4 0.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-trcl PF13451.1 KFO94848.1 - 0.00035 20.1 1.3 0.052 13.1 0.0 2.3 2 1 0 2 2 2 1 Probable zinc-binding domain DUF2256 PF10013.4 KFO94848.1 - 0.0015 18.2 7.8 0.18 11.5 0.4 2.3 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) DUF329 PF03884.9 KFO94848.1 - 0.0021 17.5 1.9 0.29 10.6 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF329) zinc_ribbon_5 PF13719.1 KFO94848.1 - 0.0031 17.0 1.8 0.035 13.6 1.3 2.1 1 1 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFO94848.1 - 0.0035 17.2 3.9 0.11 12.4 0.6 2.3 1 1 1 2 2 2 2 Zinc ribbon domain zinc_ribbon_4 PF13717.1 KFO94848.1 - 0.0035 17.0 1.4 0.043 13.5 1.0 2.1 1 1 0 1 1 1 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO94848.1 - 0.0059 16.3 1.9 0.012 15.4 1.2 1.7 1 1 0 1 1 1 1 Transposase zinc-ribbon domain LIM PF00412.17 KFO94848.1 - 0.0066 16.5 0.5 0.0094 15.9 0.4 1.3 1 1 0 1 1 1 1 LIM domain zinc_ribbon_2 PF13240.1 KFO94848.1 - 0.0081 15.6 7.1 0.051 13.0 0.4 2.4 2 0 0 2 2 2 1 zinc-ribbon domain zf-Di19 PF05605.7 KFO94848.1 - 0.012 15.6 0.3 0.051 13.6 0.2 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2321 PF10083.4 KFO94848.1 - 0.013 14.9 2.1 0.11 11.9 1.5 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) FYVE PF01363.16 KFO94848.1 - 0.015 15.1 3.0 0.069 13.0 1.1 2.0 1 1 1 2 2 2 0 FYVE zinc finger CpXC PF14353.1 KFO94848.1 - 0.016 15.2 0.1 0.25 11.3 0.1 2.0 1 1 0 1 1 1 0 CpXC protein DZR PF12773.2 KFO94848.1 - 0.016 14.9 1.5 0.023 14.5 1.1 1.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_jaz PF12171.3 KFO94848.1 - 0.023 14.8 2.5 3 8.1 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFO94848.1 - 0.027 14.2 1.0 0.027 14.2 0.7 1.5 2 0 0 2 2 1 0 BED zinc finger ADK_lid PF05191.9 KFO94848.1 - 0.067 12.8 1.8 2.1 8.1 1.4 2.2 1 1 1 2 2 2 0 Adenylate kinase, active site lid zinc-ribbons_6 PF07191.7 KFO94848.1 - 0.07 12.9 0.8 0.54 10.0 0.6 2.0 1 1 0 1 1 1 0 zinc-ribbons YhfH PF14149.1 KFO94848.1 - 0.073 12.8 2.4 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein zf-DNA_Pol PF08996.5 KFO94848.1 - 0.074 12.4 0.5 0.079 12.3 0.3 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger UPF0547 PF10571.4 KFO94848.1 - 0.076 12.7 4.1 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 IBR PF01485.16 KFO94848.1 - 0.091 12.6 2.5 0.33 10.8 1.7 1.9 1 1 0 1 1 1 0 IBR domain zf-ribbon_3 PF13248.1 KFO94848.1 - 0.093 11.9 5.9 1.2 8.4 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_5 PF14787.1 KFO94848.1 - 0.096 12.1 9.5 0.92 9.0 0.6 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-AN1 PF01428.11 KFO94848.1 - 0.098 12.5 0.4 0.098 12.5 0.3 2.4 3 0 0 3 3 2 0 AN1-like Zinc finger T4_baseplate PF12322.3 KFO94848.1 - 0.17 11.1 0.3 0.67 9.1 0.2 1.7 1 1 1 2 2 2 0 T4 bacteriophage base plate protein Nudix_N_2 PF14803.1 KFO94848.1 - 0.17 11.5 1.5 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal ZZ PF00569.12 KFO94848.1 - 0.21 11.1 3.8 6.6 6.3 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type DNA_RNApol_7kD PF03604.8 KFO94848.1 - 0.23 10.9 1.8 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.13 KFO94848.1 - 0.24 11.0 5.8 4.4 7.0 4.0 2.5 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) DUF2072 PF09845.4 KFO94848.1 - 0.42 10.5 2.0 1.3 8.9 0.3 1.9 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) PhnA_Zn_Ribbon PF08274.7 KFO94848.1 - 0.57 10.0 3.0 4.7 7.0 0.2 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-LYAR PF08790.6 KFO94848.1 - 0.63 9.8 4.3 7.5 6.3 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-ISL3 PF14690.1 KFO94848.1 - 0.64 10.1 4.9 9.7 6.3 0.4 2.4 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 XPA_N PF01286.13 KFO94848.1 - 0.75 9.5 8.8 0.63 9.7 0.6 2.3 2 1 0 2 2 2 0 XPA protein N-terminal DUF1610 PF07754.6 KFO94848.1 - 0.92 9.6 8.5 0.75 9.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-C2HC_2 PF13913.1 KFO94848.1 - 0.96 9.1 5.8 0.45 10.2 0.6 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFO94848.1 - 0.99 9.4 6.8 11 6.0 1.8 2.3 2 0 0 2 2 2 0 zinc-finger A2L_zn_ribbon PF08792.5 KFO94848.1 - 1.9 8.0 5.1 5.5 6.5 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Mss51 PF13824.1 KFO94848.1 - 3.9 7.4 5.2 33 4.4 3.6 2.2 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-H2C2_5 PF13909.1 KFO94848.1 - 7.1 7.0 10.7 19 5.7 2.6 2.7 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KFO94849.1 - 8.7e-09 35.2 10.2 1.9e-06 27.8 1.8 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94849.1 - 6.3e-07 29.3 0.1 6.3e-07 29.3 0.1 1.8 3 0 0 3 3 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94849.1 - 7.8e-06 25.8 0.3 7.8e-06 25.8 0.2 1.8 2 0 0 2 2 1 1 C2H2-type zinc finger zf-RING_3 PF14369.1 KFO94849.1 - 0.0034 17.3 0.1 0.0058 16.5 0.1 1.4 1 0 0 1 1 1 1 zinc-finger zf-C2H2_6 PF13912.1 KFO94849.1 - 0.0059 16.4 0.1 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.7 KFO94849.1 - 0.0067 16.5 0.4 0.009 16.1 0.3 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_2 PF13240.1 KFO94849.1 - 0.067 12.6 0.3 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 KFO94849.1 - 0.073 12.7 1.6 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type XPA_N PF01286.13 KFO94849.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 XPA protein N-terminal zf-CCHC_5 PF14787.1 KFO94849.1 - 0.085 12.3 1.1 0.16 11.5 0.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF1610 PF07754.6 KFO94849.1 - 0.093 12.8 0.9 0.093 12.8 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) GAGA PF09237.6 KFO94849.1 - 0.093 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 GAGA factor zf-H2C2_5 PF13909.1 KFO94849.1 - 0.13 12.5 1.4 0.13 12.5 0.9 2.6 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFO94850.1 - 3.5e-11 42.7 7.2 1.8e-05 24.7 0.8 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO94850.1 - 3e-10 39.8 1.0 3e-10 39.8 0.7 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO94850.1 - 1.1e-08 34.7 3.9 0.00017 21.6 0.4 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO94850.1 - 1.3e-06 28.1 7.3 0.008 16.0 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger XPA_N PF01286.13 KFO94850.1 - 0.00013 21.6 4.6 0.027 14.1 0.1 2.2 2 0 0 2 2 2 2 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFO94850.1 - 0.0002 21.2 3.2 0.03 14.2 2.3 2.2 1 1 1 2 2 2 2 Zinc ribbon domain zf-trcl PF13451.1 KFO94850.1 - 0.00043 19.8 1.4 0.074 12.6 0.1 2.2 2 0 0 2 2 2 1 Probable zinc-binding domain zf-C2H2_jaz PF12171.3 KFO94850.1 - 0.0005 20.1 2.0 0.0084 16.2 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO94850.1 - 0.00094 19.2 4.6 0.023 14.9 0.5 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type LIM PF00412.17 KFO94850.1 - 0.0027 17.7 1.0 0.0057 16.6 0.7 1.5 1 1 0 1 1 1 1 LIM domain zf-IS66 PF13005.2 KFO94850.1 - 0.013 15.4 0.3 1.3 9.0 0.0 2.1 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 Zn_ribbon_recom PF13408.1 KFO94850.1 - 0.021 15.0 0.5 3.5 7.9 0.1 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO94850.1 - 0.023 14.5 1.2 0.042 13.6 0.8 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 KFO94850.1 - 0.025 13.7 1.3 1 8.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 KFO94850.1 - 0.028 14.1 0.6 0.1 12.3 0.4 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GCC2_GCC3 PF07699.8 KFO94850.1 - 0.029 13.9 1.2 0.056 13.0 0.8 1.5 1 1 0 1 1 1 0 GCC2 and GCC3 zinc_ribbon_2 PF13240.1 KFO94850.1 - 0.048 13.1 5.7 0.19 11.2 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFO94850.1 - 0.05 13.2 3.0 0.18 11.4 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.1 KFO94850.1 - 0.056 13.2 5.7 0.44 10.3 1.1 2.4 1 1 1 2 2 2 0 YhfH-like protein Gin PF10764.4 KFO94850.1 - 0.073 12.7 0.2 0.39 10.4 0.1 1.9 1 1 1 2 2 2 0 Inhibitor of sigma-G Gin zf-BED PF02892.10 KFO94850.1 - 0.081 12.6 1.6 0.13 12.0 0.5 1.8 1 1 1 2 2 2 0 BED zinc finger DNA_RNApol_7kD PF03604.8 KFO94850.1 - 0.086 12.3 1.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.1 KFO94850.1 - 0.094 12.4 1.1 0.85 9.3 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L44 PF00935.14 KFO94850.1 - 0.12 12.4 1.0 2.8 8.0 0.2 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 zinc_ribbon_4 PF13717.1 KFO94850.1 - 0.12 12.1 2.9 0.47 10.1 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 KFO94850.1 - 0.13 12.4 0.7 2.1 8.5 0.2 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 KFO94850.1 - 0.13 12.0 1.0 0.21 11.4 0.7 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 KFO94850.1 - 0.14 12.1 2.5 2.8 8.0 0.1 2.1 2 0 0 2 2 2 0 zinc-finger UPF0547 PF10571.4 KFO94850.1 - 0.16 11.7 3.0 0.52 10.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Stc1 PF12898.2 KFO94850.1 - 0.17 11.9 2.1 0.2 11.7 1.4 1.3 1 0 0 1 1 1 0 Stc1 domain Nudix_N_2 PF14803.1 KFO94850.1 - 0.21 11.2 2.2 4.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zf-dskA_traR PF01258.12 KFO94850.1 - 0.23 11.2 2.8 5.8 6.7 0.3 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger IBR PF01485.16 KFO94850.1 - 0.25 11.2 1.8 1 9.2 1.3 1.8 1 1 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 KFO94850.1 - 0.45 10.4 4.4 0.35 10.7 0.2 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger zf-LYAR PF08790.6 KFO94850.1 - 0.54 10.0 6.1 4.2 7.1 0.3 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger TFIIS_C PF01096.13 KFO94850.1 - 0.66 9.6 4.5 1 9.0 0.3 2.2 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-H2C2_5 PF13909.1 KFO94850.1 - 1.1 9.6 10.6 9.2 6.7 0.5 2.9 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_3 PF13878.1 KFO94850.1 - 1.6 8.3 5.3 1.4 8.5 0.4 2.6 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO 7tm_1 PF00001.16 KFO94851.1 - 8.6e-05 21.7 0.1 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.22 KFO94852.1 - 8.9e-09 35.0 0.0 1.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_4 PF13853.1 KFO94854.1 - 3.6e-24 85.2 4.3 3.8e-24 85.1 3.0 1.0 1 0 0 1 1 1 1 Olfactory receptor DUF1242 PF06842.7 KFO94854.1 - 0.033 13.7 0.7 0.053 13.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) DUF4519 PF15012.1 KFO94854.1 - 0.036 13.9 0.2 0.086 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) 7tm_1 PF00001.16 KFO94854.1 - 0.19 10.8 1.5 0.23 10.5 1.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3955 PF13127.1 KFO94854.1 - 0.56 9.7 0.0 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) Glyco_trans_4_4 PF13579.1 KFO94855.1 - 0.033 14.3 0.4 0.037 14.1 0.3 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain zf-H2C2_2 PF13465.1 KFO94856.1 - 5.4e-30 102.1 55.1 4.5e-09 36.1 0.6 6.7 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94856.1 - 1e-23 82.1 47.8 8.6e-06 25.7 1.7 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94856.1 - 2e-17 62.1 46.2 0.00037 20.6 0.2 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO94856.1 - 3.9e-10 39.2 28.7 0.034 14.0 0.1 6.6 6 1 0 6 6 6 4 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFO94856.1 - 3.2e-07 30.1 24.7 0.55 10.2 0.1 5.9 3 1 2 5 5 5 5 Zinc ribbon domain XPA_N PF01286.13 KFO94856.1 - 5.7e-07 29.0 14.3 2.6 7.8 0.1 6.1 6 0 0 6 6 6 3 XPA protein N-terminal zf-C2H2_jaz PF12171.3 KFO94856.1 - 1e-05 25.5 32.2 0.023 14.8 1.2 6.1 7 0 0 7 7 6 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KFO94856.1 - 0.00058 19.4 0.6 0.091 12.4 0.0 5.2 5 1 1 6 6 5 2 zinc-finger of a C2HC-type GAGA PF09237.6 KFO94856.1 - 0.0015 18.0 4.8 0.87 9.2 0.0 3.5 3 1 1 4 4 4 2 GAGA factor zf-ribbon_3 PF13248.1 KFO94856.1 - 0.003 16.7 21.3 0.28 10.4 0.2 5.2 5 0 0 5 5 5 2 zinc-ribbon domain FYDLN_acid PF09538.5 KFO94856.1 - 0.0082 16.7 13.2 5.9 7.5 0.4 5.1 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-trcl PF13451.1 KFO94856.1 - 0.011 15.3 17.2 1.2 8.8 1.3 4.8 5 1 0 5 5 4 0 Probable zinc-binding domain zf-Di19 PF05605.7 KFO94856.1 - 0.012 15.6 2.9 0.012 15.6 2.0 4.3 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF329 PF03884.9 KFO94856.1 - 0.064 12.8 17.2 4.5 6.8 0.1 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF329) zf-RING_3 PF14369.1 KFO94856.1 - 0.17 11.9 20.9 0.99 9.4 0.1 5.3 5 1 1 6 6 5 0 zinc-finger TFIIS_C PF01096.13 KFO94856.1 - 0.39 10.3 26.5 3.1 7.5 0.1 5.7 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) UPF0547 PF10571.4 KFO94856.1 - 0.4 10.4 24.7 0.86 9.3 0.2 5.2 6 0 0 6 6 5 0 Uncharacterised protein family UPF0547 CpXC PF14353.1 KFO94856.1 - 0.41 10.6 19.8 0.65 9.9 1.0 4.8 2 1 3 5 5 4 0 CpXC protein zinc_ribbon_2 PF13240.1 KFO94856.1 - 0.54 9.8 30.2 0.29 10.6 0.3 5.4 5 0 0 5 5 5 0 zinc-ribbon domain TerY-C PF15616.1 KFO94856.1 - 0.63 9.9 21.0 0.063 13.2 3.7 3.1 1 1 2 3 3 2 0 TerY-C metal binding domain DZR PF12773.2 KFO94856.1 - 0.95 9.3 25.3 1.1e+02 2.6 0.1 3.9 1 1 1 2 2 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 KFO94856.1 - 1 8.7 17.3 1.1 8.6 0.2 4.4 4 0 0 4 4 4 0 TFIIB zinc-binding YhfH PF14149.1 KFO94856.1 - 1.6 8.6 23.9 6.2 6.7 0.0 5.4 5 1 0 6 6 6 0 YhfH-like protein DNA_RNApol_7kD PF03604.8 KFO94856.1 - 1.9 8.0 19.1 7.7 6.0 0.1 5.5 5 1 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 KFO94856.1 - 2.6 7.7 20.3 30 4.3 0.0 3.9 1 1 0 2 2 1 0 Hydrogenase expression/synthesis hypA family C1_3 PF07649.7 KFO94856.1 - 2.9 8.0 20.5 3.3 7.8 0.1 5.7 6 0 0 6 6 6 0 C1-like domain RRN7 PF11781.3 KFO94856.1 - 3.2 7.3 12.1 12 5.5 0.0 4.7 5 0 0 5 5 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 COX5B PF01215.14 KFO94856.1 - 3.8 7.1 19.2 5.7 6.6 0.1 4.4 1 1 0 4 4 4 0 Cytochrome c oxidase subunit Vb zf-LYAR PF08790.6 KFO94856.1 - 3.9 7.2 23.5 6 6.6 0.7 5.9 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger zinc_ribbon_5 PF13719.1 KFO94856.1 - 4.3 7.0 29.4 2.5 7.7 0.3 5.1 5 0 0 5 5 5 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFO94856.1 - 5.2 6.8 28.2 2.8 7.7 0.2 5.1 5 0 0 5 5 5 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO94856.1 - 7 6.5 34.6 0.74 9.6 3.6 4.5 3 3 1 4 4 4 0 Transposase zinc-ribbon domain DUF2256 PF10013.4 KFO94856.1 - 7.1 6.4 23.6 9 6.1 0.1 5.4 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C4_Topoisom PF01396.14 KFO94856.1 - 8.8 5.9 14.3 4.8 6.7 0.1 4.1 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger LSM PF01423.17 KFO94857.1 - 8.9e-09 34.7 0.0 1.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.3 KFO94857.1 - 0.16 12.3 2.9 0.22 11.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) 7tm_4 PF13853.1 KFO94858.1 - 5.2e-07 29.5 5.9 5.9e-07 29.3 4.1 1.1 1 0 0 1 1 1 1 Olfactory receptor MFS_1 PF07690.11 KFO94858.1 - 0.026 13.2 0.4 0.027 13.1 0.3 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Pkinase PF00069.20 KFO94859.1 - 7.3e-27 94.1 0.3 8e-27 94.0 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO94859.1 - 7.7e-16 57.9 0.1 8.5e-16 57.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO94859.1 - 0.0015 17.5 0.1 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO94859.1 - 0.0069 16.1 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFO94859.1 - 0.063 12.2 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 KFO94859.1 - 0.074 11.8 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KFO94859.1 - 0.11 11.8 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 RIO1 family GvpK PF05121.7 KFO94859.1 - 0.14 11.9 0.4 0.32 10.8 0.3 1.7 1 1 0 1 1 1 0 Gas vesicle protein K zf-C2H2 PF00096.21 KFO94860.1 - 4.4e-13 48.7 11.4 4.7e-07 29.7 1.2 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO94860.1 - 1.1e-09 38.0 15.8 2.3e-07 30.7 1.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO94860.1 - 1.7e-08 34.2 8.0 0.00013 22.0 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger XPA_N PF01286.13 KFO94860.1 - 4.5e-07 29.4 1.5 0.0098 15.5 0.2 2.1 2 0 0 2 2 2 2 XPA protein N-terminal zf-C2H2_6 PF13912.1 KFO94860.1 - 4.7e-06 26.2 9.8 0.0018 18.0 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO94860.1 - 0.00016 21.6 6.5 0.034 14.3 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFO94860.1 - 0.00039 20.3 2.5 0.048 13.6 0.1 2.1 2 0 0 2 2 2 1 Zinc ribbon domain zf-ribbon_3 PF13248.1 KFO94860.1 - 0.005 15.9 0.9 2.2 7.5 0.2 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFO94860.1 - 0.0054 16.1 2.8 0.02 14.3 1.9 1.8 1 1 0 1 1 1 1 zinc-ribbon domain zf-UBP PF02148.14 KFO94860.1 - 0.0077 16.3 3.5 0.012 15.6 2.4 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein TFIIS_C PF01096.13 KFO94860.1 - 0.0094 15.5 3.2 0.11 12.1 0.1 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) zf-met PF12874.2 KFO94860.1 - 0.014 15.5 9.5 0.12 12.5 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.8 KFO94860.1 - 0.014 14.8 1.9 0.91 9.0 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit YhfH PF14149.1 KFO94860.1 - 0.016 14.9 3.1 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein C1_1 PF00130.17 KFO94860.1 - 0.031 14.0 0.1 0.053 13.2 0.1 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.7 KFO94860.1 - 0.033 14.3 3.0 0.088 12.9 2.1 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KFO94860.1 - 0.038 13.7 7.6 1.4 8.7 4.0 2.1 1 1 1 2 2 2 0 BED zinc finger zf-LYAR PF08790.6 KFO94860.1 - 0.059 13.0 2.4 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger GCC2_GCC3 PF07699.8 KFO94860.1 - 0.075 12.6 2.6 0.29 10.7 1.8 1.8 1 1 0 1 1 1 0 GCC2 and GCC3 Viral_NABP PF05515.6 KFO94860.1 - 0.078 13.2 1.1 0.087 13.1 0.7 1.1 1 0 0 1 1 1 0 Viral nucleic acid binding DUF2072 PF09845.4 KFO94860.1 - 0.081 12.8 1.2 4 7.3 0.1 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) LIM PF00412.17 KFO94860.1 - 0.095 12.7 2.3 0.4 10.8 1.6 1.8 1 1 0 1 1 1 0 LIM domain zf-C2H2_2 PF12756.2 KFO94860.1 - 0.099 12.7 3.9 0.44 10.6 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 KFO94860.1 - 0.13 12.3 1.4 9.6 6.3 0.0 2.2 2 0 0 2 2 2 0 zinc-finger UPF0547 PF10571.4 KFO94860.1 - 0.14 11.8 2.9 6 6.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn_ribbon_recom PF13408.1 KFO94860.1 - 0.15 12.3 1.8 0.25 11.6 1.3 1.5 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain C1_4 PF07975.7 KFO94860.1 - 0.15 12.1 1.9 0.2 11.7 1.3 1.3 1 1 0 1 1 1 0 TFIIH C1-like domain Yippee-Mis18 PF03226.9 KFO94860.1 - 0.16 12.0 1.5 9 6.4 0.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rpr2 PF04032.11 KFO94860.1 - 0.16 11.8 0.6 0.22 11.4 0.4 1.2 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_7 PF15269.1 KFO94860.1 - 0.23 11.3 1.2 0.23 11.3 0.1 1.5 1 1 1 2 2 2 0 Zinc-finger TF_Zn_Ribbon PF08271.7 KFO94860.1 - 0.39 10.0 1.9 4.4 6.7 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding C1_2 PF03107.11 KFO94860.1 - 0.4 10.8 2.5 1.9 8.6 0.1 2.1 2 0 0 2 2 2 0 C1 domain FYVE PF01363.16 KFO94860.1 - 0.43 10.4 3.4 3.5 7.5 2.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger zinc_ribbon_5 PF13719.1 KFO94860.1 - 0.5 9.9 2.3 10 5.8 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 KFO94860.1 - 0.56 9.9 6.4 2.2 8.0 0.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L44 PF00935.14 KFO94860.1 - 0.58 10.2 3.5 1 9.4 0.2 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Zn_Tnp_IS1595 PF12760.2 KFO94860.1 - 0.67 9.8 6.8 2.8 7.8 4.7 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-trcl PF13451.1 KFO94860.1 - 0.7 9.5 3.0 5.1 6.8 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain A2L_zn_ribbon PF08792.5 KFO94860.1 - 1.2 8.7 4.2 2.3 7.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-tcix PF14952.1 KFO94860.1 - 1.4 8.2 3.5 11 5.3 0.0 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding OrfB_Zn_ribbon PF07282.6 KFO94860.1 - 2.3 7.9 5.1 11 5.7 3.5 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Gag_p30 PF02093.11 KFO94861.1 - 4e-22 78.4 0.1 4.9e-22 78.2 0.1 1.0 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFO94861.1 - 0.0079 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) zf-C2H2 PF00096.21 KFO94862.1 - 1.1e-13 50.5 11.6 3.1e-07 30.3 0.6 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO94862.1 - 2.4e-10 40.1 15.1 1.4e-09 37.7 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO94862.1 - 2.2e-09 36.9 9.0 3.4e-05 23.8 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO94862.1 - 1.9e-06 27.5 7.3 0.0013 18.5 0.3 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFO94862.1 - 5.1e-06 25.9 6.7 3.4e-05 23.3 0.1 2.4 3 0 0 3 3 2 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 KFO94862.1 - 1.8e-05 24.5 2.6 0.021 14.7 0.4 2.1 2 0 0 2 2 2 2 Zinc ribbon domain zf-ribbon_3 PF13248.1 KFO94862.1 - 0.00021 20.3 3.2 0.1 11.8 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFO94862.1 - 0.00033 20.0 2.4 0.22 11.0 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain XPA_N PF01286.13 KFO94862.1 - 0.00049 19.7 1.9 0.026 14.2 0.2 2.1 2 0 0 2 2 2 1 XPA protein N-terminal zf-TFIIB PF13453.1 KFO94862.1 - 0.0015 17.7 0.6 0.03 13.5 0.7 2.0 1 1 1 2 2 2 1 Transcription factor zinc-finger zf-Di19 PF05605.7 KFO94862.1 - 0.0015 18.5 2.8 0.019 15.0 2.0 2.0 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.1 KFO94862.1 - 0.0017 17.8 2.9 0.56 9.8 0.1 2.1 2 0 0 2 2 2 2 zinc-ribbon domain ADK_lid PF05191.9 KFO94862.1 - 0.0019 17.8 3.0 0.076 12.6 0.4 2.2 2 0 0 2 2 2 1 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.2 KFO94862.1 - 0.0019 17.9 2.2 0.0063 16.3 1.4 1.8 1 1 1 2 2 2 2 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 KFO94862.1 - 0.0022 17.9 1.5 0.15 12.0 0.0 2.1 2 0 0 2 2 2 1 zinc-finger A2L_zn_ribbon PF08792.5 KFO94862.1 - 0.0024 17.2 2.8 0.72 9.3 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain C1_1 PF00130.17 KFO94862.1 - 0.0041 16.8 0.0 0.0057 16.3 0.0 1.3 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CpXC PF14353.1 KFO94862.1 - 0.0044 16.9 0.6 0.36 10.8 0.4 2.0 1 1 0 1 1 1 1 CpXC protein Ogr_Delta PF04606.7 KFO94862.1 - 0.0054 16.3 1.3 0.073 12.7 0.9 1.9 1 1 1 2 2 2 1 Ogr/Delta-like zinc finger zf-IS66 PF13005.2 KFO94862.1 - 0.0055 16.6 0.5 0.63 10.0 0.0 2.2 2 0 0 2 2 2 1 zinc-finger binding domain of transposase IS66 zinc_ribbon_4 PF13717.1 KFO94862.1 - 0.0057 16.3 2.8 0.95 9.2 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain TerY-C PF15616.1 KFO94862.1 - 0.0062 16.4 0.4 0.0074 16.2 0.3 1.1 1 0 0 1 1 1 1 TerY-C metal binding domain TF_Zn_Ribbon PF08271.7 KFO94862.1 - 0.0063 15.8 2.1 0.38 10.1 0.1 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding zf-C4_Topoisom PF01396.14 KFO94862.1 - 0.0066 15.9 1.2 1.8 8.1 0.1 2.3 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger zf-ISL3 PF14690.1 KFO94862.1 - 0.0067 16.4 3.7 0.51 10.4 0.5 2.2 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 YhfH PF14149.1 KFO94862.1 - 0.0068 16.1 0.6 0.53 10.1 0.0 2.2 2 0 0 2 2 2 1 YhfH-like protein Zn_ribbon_recom PF13408.1 KFO94862.1 - 0.0069 16.6 1.2 0.04 14.1 0.9 1.9 1 1 0 1 1 1 1 Recombinase zinc beta ribbon domain FYDLN_acid PF09538.5 KFO94862.1 - 0.007 16.9 0.3 0.89 10.1 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (FYDLN_acid) DZR PF12773.2 KFO94862.1 - 0.0071 16.1 0.6 0.014 15.1 0.4 1.5 1 1 0 1 1 1 1 Double zinc ribbon DUF329 PF03884.9 KFO94862.1 - 0.0076 15.7 1.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF329) UPF0547 PF10571.4 KFO94862.1 - 0.009 15.6 5.1 0.72 9.6 0.5 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 zf-Mss51 PF13824.1 KFO94862.1 - 0.01 15.6 3.9 0.036 13.9 2.7 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 C1_3 PF07649.7 KFO94862.1 - 0.011 15.7 0.2 0.011 15.7 0.1 1.7 2 0 0 2 2 1 0 C1-like domain zf-C2H2_jaz PF12171.3 KFO94862.1 - 0.012 15.7 3.3 1 9.6 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sgf11 PF08209.6 KFO94862.1 - 0.013 14.8 0.4 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Lar_restr_allev PF14354.1 KFO94862.1 - 0.014 15.6 0.6 0.017 15.3 0.4 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar Prok-RING_1 PF14446.1 KFO94862.1 - 0.03 14.0 2.1 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TFIIS_C PF01096.13 KFO94862.1 - 0.031 13.9 2.2 2.1 8.0 0.2 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CSL PF05207.8 KFO94862.1 - 0.031 13.7 0.7 0.55 9.7 0.5 2.0 1 1 1 2 2 2 0 CSL zinc finger zf-RING_2 PF13639.1 KFO94862.1 - 0.035 13.9 1.3 0.12 12.1 0.9 1.8 1 1 0 1 1 1 0 Ring finger domain Ribosomal_L44 PF00935.14 KFO94862.1 - 0.038 14.0 0.5 4.2 7.4 0.1 2.0 1 1 1 2 2 2 0 Ribosomal protein L44 HNH PF01844.18 KFO94862.1 - 0.053 13.3 2.4 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease Nudix_N_2 PF14803.1 KFO94862.1 - 0.059 13.0 0.5 8.6 6.1 0.0 2.3 2 1 0 2 2 2 0 Nudix N-terminal PhnA_Zn_Ribbon PF08274.7 KFO94862.1 - 0.067 12.9 1.7 5.2 6.9 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-BED PF02892.10 KFO94862.1 - 0.067 12.9 1.5 0.067 12.9 1.1 2.3 2 1 0 2 2 2 0 BED zinc finger zf-CCHC_5 PF14787.1 KFO94862.1 - 0.067 12.6 7.1 0.71 9.4 0.1 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF2225 PF09986.4 KFO94862.1 - 0.069 12.6 0.6 0.98 8.8 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) FYVE PF01363.16 KFO94862.1 - 0.081 12.8 3.0 5 7.1 0.0 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-AN1 PF01428.11 KFO94862.1 - 0.083 12.7 4.0 0.35 10.7 0.3 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger Rad50_zn_hook PF04423.9 KFO94862.1 - 0.086 12.3 1.1 4.6 6.7 0.0 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif HypA PF01155.14 KFO94862.1 - 0.098 12.3 0.1 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family T4_baseplate PF12322.3 KFO94862.1 - 0.12 11.6 0.2 0.75 9.0 0.0 1.9 1 1 1 2 2 2 0 T4 bacteriophage base plate protein zf-NADH-PPase PF09297.6 KFO94862.1 - 0.13 11.8 1.3 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-trcl PF13451.1 KFO94862.1 - 0.13 11.8 0.8 4 7.1 0.0 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain zf-C2H2_2 PF12756.2 KFO94862.1 - 0.13 12.3 1.2 3.1 7.9 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-HIT PF04438.11 KFO94862.1 - 0.14 11.8 5.6 0.34 10.6 0.5 2.1 2 0 0 2 2 2 0 HIT zinc finger SprT-like PF10263.4 KFO94862.1 - 0.15 11.7 0.7 0.15 11.7 0.5 1.1 1 0 0 1 1 1 0 SprT-like family zf-LYAR PF08790.6 KFO94862.1 - 0.15 11.8 4.7 0.74 9.5 1.1 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Cys_rich_CWC PF14375.1 KFO94862.1 - 0.21 11.5 1.0 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC DUF2256 PF10013.4 KFO94862.1 - 0.23 11.2 1.1 16 5.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) OrfB_Zn_ribbon PF07282.6 KFO94862.1 - 0.23 11.1 1.0 0.79 9.4 0.7 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-tcix PF14952.1 KFO94862.1 - 0.23 10.8 3.7 4.6 6.6 0.1 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Cys_rich_CPXG PF14255.1 KFO94862.1 - 0.24 11.2 1.4 6.4 6.6 0.1 2.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-met PF12874.2 KFO94862.1 - 0.28 11.4 7.2 4.2 7.7 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF35_N PF12172.3 KFO94862.1 - 0.31 10.9 3.1 3 7.8 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-CCHC PF00098.18 KFO94862.1 - 0.38 10.7 6.7 2.7 8.0 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle Rubredoxin PF00301.15 KFO94862.1 - 0.83 9.5 3.3 3.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin DUF1610 PF07754.6 KFO94862.1 - 0.89 9.7 14.5 1 9.5 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) 7tm_4 PF13853.1 KFO94863.1 - 9.8e-59 197.2 9.6 1.2e-58 197.0 6.7 1.1 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO94863.1 - 2.5e-08 33.3 6.7 3.7e-08 32.8 4.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.1 KFO94865.1 - 4.9e-14 51.8 15.7 5.4e-08 32.7 1.4 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94865.1 - 3.8e-06 26.9 3.3 3.8e-06 26.9 2.3 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 KFO94865.1 - 0.0049 16.7 5.5 0.097 12.6 3.7 2.1 1 1 0 1 1 1 1 Zinc ribbon domain zf-C2H2_4 PF13894.1 KFO94865.1 - 0.012 15.9 1.5 0.012 15.9 1.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO94865.1 - 0.019 15.0 0.1 0.019 15.0 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.6 KFO94865.1 - 0.071 12.8 0.3 0.18 11.5 0.2 1.9 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger XPA_N PF01286.13 KFO94865.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_6 PF13912.1 KFO94865.1 - 0.17 11.8 0.9 0.17 11.8 0.6 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Elf1 PF05129.8 KFO94865.1 - 0.27 10.9 2.1 0.31 10.7 1.4 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.1 KFO94865.1 - 0.29 10.6 7.9 3 7.4 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 KFO94865.1 - 0.29 10.8 1.5 0.33 10.6 1.0 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-BED PF02892.10 KFO94865.1 - 0.43 10.3 16.5 0.13 12.0 5.5 2.7 1 1 2 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 KFO94865.1 - 1.9 8.3 8.9 1.4 8.7 0.2 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 KFO94865.1 - 2.1 7.6 7.1 3 7.1 0.3 2.5 2 1 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.1 KFO94865.1 - 2.5 7.9 7.1 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein TFIIS_C PF01096.13 KFO94865.1 - 5.9 6.6 6.9 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) RVT_1 PF00078.22 KFO94866.1 - 1.6e-09 37.4 0.0 3.2e-09 36.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 KFO94868.1 - 8.2e-14 51.0 6.5 3.5e-08 33.3 2.2 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94868.1 - 4.1e-09 36.1 6.2 2.1e-05 24.4 2.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO94868.1 - 5.7e-07 29.5 0.6 5.7e-07 29.5 0.4 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFO94868.1 - 6.1e-06 26.2 0.5 0.049 13.8 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO94868.1 - 0.00081 19.2 9.7 0.15 12.0 2.3 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFO94868.1 - 0.0019 18.1 2.4 0.18 11.8 1.6 2.2 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2HC_2 PF13913.1 KFO94868.1 - 0.0088 15.6 9.3 0.093 12.4 2.9 2.9 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KFO94868.1 - 0.011 15.8 0.6 2.9 8.0 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFO94868.1 - 0.013 15.6 0.9 2.2 8.6 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KFO94868.1 - 0.013 15.1 0.9 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger GAGA PF09237.6 KFO94868.1 - 0.018 14.6 0.3 0.019 14.5 0.2 1.3 1 1 0 1 1 1 0 GAGA factor zf-BED PF02892.10 KFO94868.1 - 0.026 14.2 3.7 4.4 7.1 2.5 2.3 1 1 0 1 1 1 0 BED zinc finger XPA_N PF01286.13 KFO94868.1 - 0.028 14.1 3.0 2.6 7.7 0.3 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-ribbon_3 PF13248.1 KFO94868.1 - 0.033 13.4 8.2 0.061 12.5 1.5 2.5 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFO94868.1 - 0.034 13.7 2.2 0.18 11.4 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFO94868.1 - 0.063 13.2 3.3 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 zinc-finger Fer4_12 PF13353.1 KFO94868.1 - 0.071 13.2 0.3 0.071 13.2 0.2 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain zf-TRAF PF02176.13 KFO94868.1 - 0.078 13.3 1.4 0.087 13.2 1.0 1.1 1 0 0 1 1 1 0 TRAF-type zinc finger zinc_ribbon_4 PF13717.1 KFO94868.1 - 0.079 12.6 2.1 0.4 10.4 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFO94868.1 - 0.082 12.4 0.6 0.082 12.4 0.4 2.7 3 0 0 3 3 3 0 zinc-ribbon domain LIM PF00412.17 KFO94868.1 - 0.087 12.9 0.8 0.12 12.4 0.5 1.3 1 1 0 1 1 1 0 LIM domain CpXC PF14353.1 KFO94868.1 - 0.095 12.6 0.5 0.76 9.7 0.2 2.0 1 1 1 2 2 2 0 CpXC protein DZR PF12773.2 KFO94868.1 - 0.098 12.4 1.6 0.2 11.4 1.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 KFO94868.1 - 0.11 11.8 0.5 0.11 11.8 0.3 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Di19 PF05605.7 KFO94868.1 - 0.11 12.5 3.0 1.3 9.1 0.7 2.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sgf11 PF08209.6 KFO94868.1 - 0.12 11.7 4.2 0.98 8.7 1.2 2.7 2 2 0 2 2 2 0 Sgf11 (transcriptional regulation protein) FYDLN_acid PF09538.5 KFO94868.1 - 0.14 12.7 0.3 0.47 11.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) FANCL_C PF11793.3 KFO94868.1 - 0.22 11.4 1.7 2.2 8.3 1.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain UPF0547 PF10571.4 KFO94868.1 - 0.28 10.9 0.4 0.28 10.9 0.3 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF2688 PF10892.3 KFO94868.1 - 0.28 10.8 1.8 0.71 9.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) TFIIS_C PF01096.13 KFO94868.1 - 0.54 9.9 5.6 0.73 9.5 0.7 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-ISL3 PF14690.1 KFO94868.1 - 0.61 10.1 5.7 0.24 11.4 1.9 1.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-HIT PF04438.11 KFO94868.1 - 2 8.1 6.3 0.5 10.0 1.3 2.0 2 0 0 2 2 2 0 HIT zinc finger YhfH PF14149.1 KFO94868.1 - 2.8 7.8 6.0 3.3 7.5 0.6 2.3 2 1 0 2 2 2 0 YhfH-like protein DUF1610 PF07754.6 KFO94868.1 - 4 7.6 13.5 0.75 9.9 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) 7tm_4 PF13853.1 KFO94869.1 - 4.5e-41 140.0 7.2 5.1e-41 139.8 5.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO94869.1 - 0.0023 17.0 3.4 0.0029 16.7 2.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.1 KFO94870.1 - 2.6e-09 36.8 18.9 6.4e-05 23.0 5.0 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94870.1 - 0.00034 20.7 4.6 0.00034 20.7 3.2 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 KFO94870.1 - 0.0032 17.3 12.2 0.012 15.5 5.4 2.8 2 1 0 2 2 2 1 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFO94870.1 - 0.0045 17.1 1.7 0.0045 17.1 1.2 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 KFO94870.1 - 0.0065 16.1 7.4 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 XPA protein N-terminal TFIIS_C PF01096.13 KFO94870.1 - 0.066 12.8 6.0 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_6 PF13912.1 KFO94870.1 - 0.1 12.5 0.8 0.1 12.5 0.6 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UBP PF02148.14 KFO94870.1 - 0.15 12.2 8.0 0.35 11.0 5.5 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DNA_RNApol_7kD PF03604.8 KFO94870.1 - 0.31 10.5 6.2 6.3 6.3 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-trcl PF13451.1 KFO94870.1 - 0.33 10.6 5.1 3.9 7.1 1.3 2.4 2 0 0 2 2 2 0 Probable zinc-binding domain C1_3 PF07649.7 KFO94870.1 - 0.37 10.8 0.4 0.37 10.8 0.2 2.2 2 0 0 2 2 2 0 C1-like domain COX5B PF01215.14 KFO94870.1 - 0.38 10.4 6.7 0.25 11.0 0.4 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Vb UPF0547 PF10571.4 KFO94870.1 - 0.5 10.1 6.9 3.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 KFO94870.1 - 0.55 9.8 5.6 6.1 6.4 1.0 2.4 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO94870.1 - 0.58 10.0 7.0 3.5 7.5 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-LYAR PF08790.6 KFO94870.1 - 0.77 9.5 5.1 0.36 10.5 0.6 2.6 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf-ribbon_3 PF13248.1 KFO94870.1 - 1.1 8.5 6.2 2.4 7.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain SprT-like PF10263.4 KFO94870.1 - 1.1 8.8 5.5 1.3 8.6 3.8 1.3 1 1 0 1 1 1 0 SprT-like family A2L_zn_ribbon PF08792.5 KFO94870.1 - 1.3 8.5 6.6 0.89 9.0 0.2 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain YhfH PF14149.1 KFO94870.1 - 2 8.2 9.8 6.2 6.7 0.1 2.9 3 1 0 3 3 3 0 YhfH-like protein HypA PF01155.14 KFO94870.1 - 4.4 7.0 6.2 6.4 6.5 4.3 1.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-H2C2_2 PF13465.1 KFO94872.1 - 5.7e-37 124.2 48.3 7.8e-10 38.5 1.0 6.1 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94872.1 - 3.8e-28 96.0 45.4 3e-07 30.4 0.2 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94872.1 - 4.1e-18 64.2 39.6 7.9e-05 22.7 0.2 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO94872.1 - 5.4e-13 48.3 27.4 0.00071 19.3 0.1 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO94872.1 - 6.1e-10 38.9 19.0 0.0071 16.4 1.4 4.9 5 0 0 5 5 4 4 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 KFO94872.1 - 5.6e-08 32.3 11.0 0.064 12.9 0.1 5.1 5 0 0 5 5 5 2 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFO94872.1 - 1e-07 31.7 23.0 0.063 13.2 0.2 5.0 3 1 1 4 4 4 4 Zinc ribbon domain zf-RING_3 PF14369.1 KFO94872.1 - 1.6e-07 31.1 13.4 0.062 13.3 0.1 5.0 5 0 0 5 5 5 2 zinc-finger C1_4 PF07975.7 KFO94872.1 - 1.7e-06 27.9 13.3 0.0088 16.0 1.1 4.1 2 1 2 4 4 4 2 TFIIH C1-like domain GAGA PF09237.6 KFO94872.1 - 2.2e-05 23.9 0.6 0.0048 16.4 0.0 2.5 1 1 1 2 2 2 1 GAGA factor zf-Di19 PF05605.7 KFO94872.1 - 9.3e-05 22.4 15.0 0.0012 18.8 1.9 3.8 1 1 3 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 KFO94872.1 - 0.00012 22.5 9.4 0.34 11.4 0.9 4.2 1 1 0 2 2 2 1 Protein of unknown function (FYDLN_acid) FYVE PF01363.16 KFO94872.1 - 0.00027 20.7 22.6 0.0078 16.0 2.1 3.1 1 1 2 3 3 3 2 FYVE zinc finger Prok-RING_1 PF14446.1 KFO94872.1 - 0.00053 19.6 12.1 3.4 7.4 0.1 5.2 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 SprT-like PF10263.4 KFO94872.1 - 0.001 18.7 17.9 0.24 11.0 1.0 3.1 1 1 1 2 2 2 2 SprT-like family zf-HIT PF04438.11 KFO94872.1 - 0.0012 18.3 24.6 0.097 12.3 1.6 5.0 5 0 0 5 5 5 2 HIT zinc finger zf-C2HC_2 PF13913.1 KFO94872.1 - 0.0019 17.8 25.3 0.11 12.1 1.1 5.0 5 0 0 5 5 5 3 zinc-finger of a C2HC-type zf-met PF12874.2 KFO94872.1 - 0.0035 17.5 21.9 0.37 11.0 1.4 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.1 KFO94872.1 - 0.0044 16.6 21.0 0.3 10.8 2.6 5.0 4 1 0 4 4 4 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFO94872.1 - 0.0052 15.9 21.7 0.35 10.1 0.4 5.1 5 0 0 5 5 5 1 zinc-ribbon domain DZR PF12773.2 KFO94872.1 - 0.0058 16.4 19.8 2.3e+03 -1.5 13.7 3.5 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 KFO94872.1 - 0.0058 16.1 21.8 0.56 9.8 3.4 5.0 4 1 0 4 4 4 1 zinc-ribbon domain HypA PF01155.14 KFO94872.1 - 0.011 15.3 15.4 2.3 7.9 3.4 3.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-BED PF02892.10 KFO94872.1 - 0.013 15.2 35.7 0.061 13.0 0.7 5.2 1 1 4 5 5 5 0 BED zinc finger zf-AN1 PF01428.11 KFO94872.1 - 0.031 14.1 0.5 0.031 14.1 0.4 5.2 3 1 2 5 5 5 0 AN1-like Zinc finger TFIIS_C PF01096.13 KFO94872.1 - 0.046 13.3 23.8 2 8.1 0.3 5.2 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) Ribosomal_L37ae PF01780.14 KFO94872.1 - 0.048 13.5 15.2 4.7 7.1 0.1 4.7 1 1 2 3 3 3 0 Ribosomal L37ae protein family zf-FPG_IleRS PF06827.9 KFO94872.1 - 0.049 13.2 16.1 13 5.4 0.1 5.3 4 1 0 4 4 4 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.2 KFO94872.1 - 0.11 12.3 32.9 1.6 8.6 4.6 4.4 3 2 1 4 4 4 0 Transposase zinc-ribbon domain zf-trcl PF13451.1 KFO94872.1 - 0.15 11.6 14.7 2.1 8.0 0.1 4.7 5 0 0 5 5 5 0 Probable zinc-binding domain zf-LYAR PF08790.6 KFO94872.1 - 0.18 11.5 18.5 3.3 7.4 0.1 5.1 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zinc_ribbon_2 PF13240.1 KFO94872.1 - 0.19 11.2 30.0 0.58 9.7 0.4 5.2 5 0 0 5 5 5 0 zinc-ribbon domain zf-ISL3 PF14690.1 KFO94872.1 - 0.42 10.6 30.9 0.57 10.2 1.4 5.4 4 1 1 5 5 5 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 YhfH PF14149.1 KFO94872.1 - 0.44 10.3 19.2 7.1 6.5 0.1 4.7 5 0 0 5 5 4 0 YhfH-like protein ROS_MUCR PF05443.6 KFO94872.1 - 0.46 10.2 4.2 2.6 7.8 0.4 2.6 2 1 1 3 3 3 0 ROS/MUCR transcriptional regulator protein zf-UBP PF02148.14 KFO94872.1 - 0.47 10.5 26.3 4.3 7.5 3.0 4.2 1 1 3 4 4 4 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C4_Topoisom PF01396.14 KFO94872.1 - 0.53 9.8 14.2 2.4 7.7 0.9 4.2 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger IBR PF01485.16 KFO94872.1 - 0.54 10.1 24.0 1.4 8.8 7.6 4.2 1 1 2 3 3 3 0 IBR domain C1_3 PF07649.7 KFO94872.1 - 0.65 10.0 14.0 12 6.0 0.2 4.8 5 0 0 5 5 5 0 C1-like domain DUF1610 PF07754.6 KFO94872.1 - 0.7 10.0 29.1 0.19 11.8 1.1 4.9 5 0 0 5 5 4 0 Domain of unknown function (DUF1610) CpXC PF14353.1 KFO94872.1 - 0.85 9.5 19.6 2 8.3 0.1 4.8 3 1 0 4 4 4 0 CpXC protein DUF3797 PF12677.2 KFO94872.1 - 0.99 9.0 12.6 1 9.0 0.1 4.2 5 0 0 5 5 4 0 Domain of unknown function (DUF3797) DNA_RNApol_7kD PF03604.8 KFO94872.1 - 1.5 8.3 18.6 1.7 8.2 0.2 5.1 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit LIM PF00412.17 KFO94872.1 - 1.6 8.8 18.9 9.4 6.3 0.1 4.4 1 1 2 4 4 4 0 LIM domain UPF0547 PF10571.4 KFO94872.1 - 1.9 8.2 26.8 5.1 6.8 0.1 5.2 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 TerY-C PF15616.1 KFO94872.1 - 2.4 8.1 14.3 1.4 8.8 4.1 2.3 1 1 1 2 2 2 0 TerY-C metal binding domain DUF164 PF02591.10 KFO94872.1 - 3.3 7.6 15.3 10 6.0 0.1 4.8 5 0 0 5 5 5 0 Putative zinc ribbon domain Ribosomal_S27e PF01667.12 KFO94872.1 - 3.8 7.1 13.1 6.2 6.4 0.2 4.5 5 0 0 5 5 5 0 Ribosomal protein S27 Desulfoferrod_N PF06397.7 KFO94872.1 - 3.9 6.9 16.7 4.4 6.7 0.2 4.7 5 0 0 5 5 5 0 Desulfoferrodoxin, N-terminal domain Evr1_Alr PF04777.8 KFO94872.1 - 4 7.4 18.5 1 9.2 2.1 4.2 1 1 3 4 4 4 0 Erv1 / Alr family Yippee-Mis18 PF03226.9 KFO94872.1 - 7.9 6.5 13.5 0.96 9.5 1.7 3.6 1 1 3 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nudix_N_2 PF14803.1 KFO94872.1 - 9.4 6.0 18.1 24 4.7 0.2 5.3 4 1 0 4 4 4 0 Nudix N-terminal 7tm_1 PF00001.16 KFO94874.1 - 1.5e-07 30.8 0.1 1.9e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.1 KFO94875.1 - 1.6e-36 122.8 36.4 4.8e-08 32.9 1.4 6.3 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94875.1 - 5.2e-27 92.5 41.4 2.2e-08 33.9 0.4 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94875.1 - 1e-16 59.9 38.4 3.1e-05 23.9 0.3 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO94875.1 - 1.4e-13 50.1 28.6 1.9e-05 24.3 0.3 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO94875.1 - 2.8e-08 33.6 13.9 0.028 14.5 0.1 5.7 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFO94875.1 - 2.6e-05 24.0 29.4 0.53 10.2 2.4 5.7 2 2 2 4 4 4 3 Zinc ribbon domain XPA_N PF01286.13 KFO94875.1 - 0.00013 21.5 14.8 4.2 7.1 0.2 6.0 6 0 0 6 6 6 0 XPA protein N-terminal zf-Di19 PF05605.7 KFO94875.1 - 0.00044 20.3 22.4 0.0053 16.8 1.8 4.6 1 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFO94875.1 - 0.001 18.6 8.5 0.046 13.4 0.1 4.2 4 0 0 4 4 3 1 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFO94875.1 - 0.0045 16.9 19.5 0.13 12.2 0.1 5.9 5 1 1 6 6 6 1 zinc-finger Zn_Tnp_IS1595 PF12760.2 KFO94875.1 - 0.005 16.6 27.5 0.0053 16.5 1.5 4.2 4 1 0 4 4 4 2 Transposase zinc-ribbon domain Prok-RING_1 PF14446.1 KFO94875.1 - 0.01 15.5 16.6 4.9 6.9 0.0 5.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.1 KFO94875.1 - 0.019 14.1 24.7 0.42 9.8 0.2 5.8 6 0 0 6 6 6 0 zinc-ribbon domain zf-met PF12874.2 KFO94875.1 - 0.033 14.4 0.1 0.033 14.4 0.1 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type DZR PF12773.2 KFO94875.1 - 0.038 13.8 21.6 9.1e+02 -0.3 12.3 4.0 2 1 0 2 2 2 0 Double zinc ribbon Evr1_Alr PF04777.8 KFO94875.1 - 0.06 13.2 12.6 0.079 12.8 1.3 3.5 1 1 3 4 4 4 0 Erv1 / Alr family C1_4 PF07975.7 KFO94875.1 - 0.088 12.8 19.0 1.6 8.7 0.3 4.8 3 2 2 5 5 5 0 TFIIH C1-like domain CpXC PF14353.1 KFO94875.1 - 0.096 12.6 19.4 0.47 10.4 0.0 5.1 3 1 1 5 5 5 0 CpXC protein TerY-C PF15616.1 KFO94875.1 - 0.1 12.5 11.9 1.1 9.1 5.0 3.1 1 1 2 3 3 3 0 TerY-C metal binding domain DUF329 PF03884.9 KFO94875.1 - 0.11 12.0 17.5 2.9 7.5 0.1 5.4 6 0 0 6 6 6 0 Domain of unknown function (DUF329) DUF2256 PF10013.4 KFO94875.1 - 0.11 12.2 16.8 1.5 8.6 0.2 5.4 6 0 0 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.6 KFO94875.1 - 0.12 12.0 0.4 0.12 12.0 0.3 5.9 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger UPF0547 PF10571.4 KFO94875.1 - 0.17 11.5 23.1 1.2 8.9 0.2 6.0 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 KFO94875.1 - 0.19 11.2 31.9 1.3 8.6 0.9 6.0 5 1 0 5 5 5 0 zinc-ribbon domain FYDLN_acid PF09538.5 KFO94875.1 - 0.25 11.9 12.1 27 5.4 1.4 5.1 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) YhfH PF14149.1 KFO94875.1 - 0.27 11.0 22.4 2.8 7.8 0.4 5.8 6 0 0 6 6 6 0 YhfH-like protein zf-trcl PF13451.1 KFO94875.1 - 0.37 10.4 20.8 4.4 7.0 5.9 4.9 5 1 0 5 5 4 0 Probable zinc-binding domain DUF1247 PF06851.6 KFO94875.1 - 0.41 10.2 2.7 0.2 11.2 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1247) Cys_rich_CPXG PF14255.1 KFO94875.1 - 0.45 10.3 4.8 11 5.9 0.0 3.6 3 0 0 3 3 3 0 Cysteine-rich CPXCG HypA PF01155.14 KFO94875.1 - 0.56 9.9 16.1 1.4 8.6 0.2 3.5 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 KFO94875.1 - 1.4 8.5 27.0 2.8 7.6 0.1 5.6 5 1 0 5 5 5 0 Transcription factor S-II (TFIIS) zinc_ribbon_5 PF13719.1 KFO94875.1 - 1.5 8.4 25.2 0.68 9.5 2.5 5.5 5 1 0 5 5 5 0 zinc-ribbon domain Ribosomal_L31 PF01197.13 KFO94875.1 - 1.5 8.8 4.4 23 5.0 2.0 3.5 1 1 1 2 2 2 0 Ribosomal protein L31 LIM PF00412.17 KFO94875.1 - 2.1 8.4 22.1 1.9 8.6 1.5 5.0 3 2 0 4 4 3 0 LIM domain zinc_ribbon_4 PF13717.1 KFO94875.1 - 4.2 7.1 25.2 0.92 9.2 2.4 5.4 5 1 0 5 5 5 0 zinc-ribbon domain Mut7-C PF01927.11 KFO94875.1 - 4.8 7.1 17.4 0.92 9.4 1.4 3.9 1 1 3 4 4 4 0 Mut7-C RNAse domain zf-BED PF02892.10 KFO94875.1 - 6.1 6.6 23.9 13 5.6 0.3 5.2 1 1 4 5 5 5 0 BED zinc finger 7tm_1 PF00001.16 KFO94876.1 - 2.7e-11 43.0 0.3 3.6e-11 42.6 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFO94877.1 - 4e-37 127.1 4.6 4.5e-37 127.0 3.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO94877.1 - 0.045 12.8 2.0 0.051 12.7 1.4 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.1 KFO94877.1 - 0.88 9.5 0.0 0.88 9.5 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) 7tm_4 PF13853.1 KFO94878.1 - 1.4e-62 209.7 12.4 1.4e-62 209.7 8.6 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO94878.1 - 1.2e-34 119.6 15.9 1.5e-34 119.3 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO94878.1 - 0.00027 20.1 14.5 0.00044 19.4 10.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RasGAP_C PF03836.10 KFO94879.1 - 0.038 13.6 0.1 0.038 13.6 0.0 1.0 1 0 0 1 1 1 0 RasGAP C-terminus Ribosomal_S30 PF04758.9 KFO94880.1 - 5.1e-18 64.5 7.7 5.4e-18 64.4 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Oxidored_q3 PF00499.15 KFO94882.1 - 2e-11 43.8 14.0 2e-11 43.8 9.7 1.3 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 EI24 PF07264.6 KFO94882.1 - 5 6.4 12.1 5.7 6.3 8.4 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Histone PF00125.19 KFO94884.1 - 1e-09 38.3 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 KbaA PF14089.1 KFO94885.1 - 0.021 14.3 1.0 0.023 14.2 0.7 1.1 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation Col_cuticle_N PF01484.12 KFO94885.1 - 0.088 12.5 3.0 2.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Nematode cuticle collagen N-terminal domain Hormone_recep PF00104.25 KFO94886.1 - 3.3e-09 36.1 0.0 3.5e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C2H2 PF00096.21 KFO94887.1 - 1.8e-12 46.8 0.8 1.4e-06 28.2 0.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94887.1 - 2.1e-09 37.0 0.7 0.00063 19.8 0.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO94887.1 - 4.2e-09 36.2 2.2 8.9e-08 32.0 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFO94887.1 - 1.1e-05 25.1 1.2 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO94887.1 - 2.7e-05 24.1 0.0 0.08 13.1 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO94887.1 - 0.00038 20.5 0.6 0.65 10.2 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 KFO94887.1 - 0.042 13.6 1.1 3.3 7.5 0.1 2.1 1 1 1 2 2 2 0 BED zinc finger Prok-RING_1 PF14446.1 KFO94887.1 - 0.058 13.1 0.5 0.26 11.0 0.2 2.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DM PF00751.13 KFO94887.1 - 0.06 12.8 1.2 0.065 12.7 0.8 1.2 1 0 0 1 1 1 0 DM DNA binding domain zf-ribbon_3 PF13248.1 KFO94887.1 - 0.096 11.9 5.2 0.34 10.1 0.5 2.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 KFO94887.1 - 0.098 12.7 1.4 0.6 10.2 0.9 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 KFO94887.1 - 0.1 12.6 2.7 1.6 8.7 0.3 2.2 2 0 0 2 2 2 0 zinc-finger zf-LYAR PF08790.6 KFO94887.1 - 0.11 12.1 0.6 1.8 8.3 0.1 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger XPA_N PF01286.13 KFO94887.1 - 0.12 12.0 2.4 0.99 9.1 0.7 2.1 2 0 0 2 2 2 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFO94887.1 - 0.13 12.2 4.2 1.1 9.2 2.9 2.1 1 1 0 1 1 1 0 Zinc ribbon domain UPF0547 PF10571.4 KFO94887.1 - 0.22 11.2 0.2 0.22 11.2 0.1 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-H2C2_5 PF13909.1 KFO94887.1 - 0.5 10.7 2.7 4.9 7.5 0.0 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 KFO94887.1 - 4.2 7.1 7.8 1.3 8.7 0.6 2.7 1 1 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.1 KFO94887.1 - 5.3 6.6 10.8 1.1 8.8 0.5 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Pkinase_Tyr PF07714.12 KFO94888.1 - 1.2e-24 86.7 0.0 1.4e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO94888.1 - 7.4e-10 38.4 0.0 7.8e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFO94888.1 - 0.077 12.7 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_1 PF00078.22 KFO94889.1 - 4.5e-28 98.0 0.0 5.4e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 KFO94890.1 - 3.6e-08 33.2 11.3 6.4e-05 23.0 1.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO94890.1 - 0.00013 22.0 4.0 0.00013 22.0 2.7 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFO94890.1 - 0.0012 18.7 3.9 0.007 16.2 0.2 2.3 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFO94890.1 - 0.0052 17.0 9.6 0.013 15.7 1.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFO94890.1 - 0.017 15.0 0.5 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain XPA_N PF01286.13 KFO94890.1 - 0.027 14.1 0.3 0.68 9.6 0.1 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_jaz PF12171.3 KFO94890.1 - 0.071 13.2 1.2 0.48 10.6 0.0 2.3 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.4 KFO94890.1 - 0.19 11.4 0.8 4.2 7.2 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.6 KFO94890.1 - 0.21 11.2 2.3 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-BED PF02892.10 KFO94890.1 - 0.72 9.6 5.7 4.7 7.0 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger zf-UBP PF02148.14 KFO94890.1 - 2.4 8.3 5.6 9.3 6.4 0.3 2.1 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein 7tm_4 PF13853.1 KFO94891.1 - 1.2e-09 38.1 4.9 1.3e-09 37.9 3.4 1.0 1 0 0 1 1 1 1 Olfactory receptor zf-H2C2_2 PF13465.1 KFO94892.1 - 5.1e-09 35.9 4.2 4.4e-05 23.5 0.2 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94892.1 - 1.9e-05 24.7 0.1 1.9e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type Cys_rich_CPXG PF14255.1 KFO94892.1 - 0.0002 21.0 0.4 0.00022 20.9 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich CPXCG zf-C2H2_4 PF13894.1 KFO94892.1 - 0.001 19.2 0.1 0.001 19.2 0.1 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 KFO94892.1 - 0.0061 16.6 2.4 0.014 15.5 1.6 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFO94892.1 - 0.022 14.6 0.1 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger FANCL_C PF11793.3 KFO94892.1 - 0.028 14.3 1.0 0.32 10.9 0.0 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain TerY-C PF15616.1 KFO94892.1 - 0.054 13.4 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain 7tm_1 PF00001.16 KFO94893.1 - 7.5e-07 28.5 0.1 9.9e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-H2C2_2 PF13465.1 KFO94895.1 - 2.3e-11 43.3 8.1 3.2e-06 27.1 1.1 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94895.1 - 2.2e-07 30.7 2.3 3.6e-07 30.1 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94895.1 - 2.6e-05 24.2 0.8 4.4e-05 23.5 0.6 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO94895.1 - 0.00034 20.4 0.6 0.00045 20.0 0.4 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFO94895.1 - 0.0065 16.3 1.4 0.0091 15.9 1.0 1.5 1 1 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_5 PF13719.1 KFO94895.1 - 0.046 13.3 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFO94895.1 - 0.05 12.8 0.1 0.071 12.3 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 KFO94895.1 - 0.051 13.2 0.8 0.051 13.2 0.5 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type LIM PF00412.17 KFO94895.1 - 0.059 13.4 0.1 0.071 13.1 0.1 1.2 1 0 0 1 1 1 0 LIM domain zinc_ribbon_2 PF13240.1 KFO94895.1 - 0.065 12.7 1.3 0.1 12.0 0.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-trcl PF13451.1 KFO94895.1 - 0.086 12.4 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Probable zinc-binding domain zf-BED PF02892.10 KFO94895.1 - 0.13 12.0 0.8 0.14 11.9 0.5 1.2 1 0 0 1 1 1 0 BED zinc finger 7tm_1 PF00001.16 KFO94896.1 - 1.9e-08 33.7 0.1 2.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4496 PF14908.1 KFO94898.1 - 2e-06 27.7 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) RVT_1 PF00078.22 KFO94899.1 - 6.8e-26 90.9 0.0 8.9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFO94899.1 - 0.001 18.6 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain BTB PF00651.26 KFO94900.1 - 5.6e-33 113.2 0.6 2.4e-32 111.1 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFO94900.1 - 8.1e-08 32.1 8.8 1.7e-07 31.1 0.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO94900.1 - 0.017 15.4 1.2 1.3 9.5 0.0 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFO94900.1 - 0.049 13.7 0.5 0.11 12.6 0.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFO94900.1 - 0.054 13.7 1.9 6.7 7.0 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BSP_II PF05432.6 KFO94900.1 - 0.1 11.8 11.0 0.15 11.3 7.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CobT PF06213.7 KFO94900.1 - 0.12 11.4 12.2 0.18 10.9 8.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.6 KFO94900.1 - 0.14 11.9 6.0 0.25 11.1 4.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal BTV_NS2 PF04514.7 KFO94900.1 - 0.15 10.9 5.9 0.25 10.1 4.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 KFO94900.1 - 0.17 9.9 4.4 0.21 9.6 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Mus7 PF09462.5 KFO94900.1 - 0.26 10.0 2.6 0.38 9.5 1.8 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family Daxx PF03344.10 KFO94900.1 - 0.36 9.2 16.6 0.49 8.8 11.5 1.1 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KFO94900.1 - 0.37 10.3 10.4 0.57 9.7 7.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 KFO94900.1 - 0.6 9.7 6.6 1.1 8.8 4.6 1.5 1 0 0 1 1 1 0 FAM176 family Mpp10 PF04006.7 KFO94900.1 - 0.67 8.2 18.6 0.95 7.7 12.9 1.1 1 0 0 1 1 1 0 Mpp10 protein zf-C2H2_jaz PF12171.3 KFO94900.1 - 0.71 10.0 2.6 1e+02 3.1 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF2722 PF10846.3 KFO94900.1 - 1.1 8.2 5.2 1.5 7.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) zf-C2H2 PF00096.21 KFO94900.1 - 1.3 9.5 7.0 4.3 7.8 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Vfa1 PF08432.5 KFO94900.1 - 1.5 8.8 9.3 0.2 11.6 1.7 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 KFO94900.1 - 2.6 5.7 6.0 3.4 5.4 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.11 KFO94900.1 - 3 6.7 7.8 4.9 6.0 5.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Keratin PF02422.11 KFO94902.1 - 9.6e-40 134.5 14.9 1.1e-39 134.3 10.3 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.12 KFO94902.1 - 0.44 10.7 9.3 0.6 10.2 6.4 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain RVT_1 PF00078.22 KFO94903.1 - 2e-17 63.2 0.0 2.9e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFO94903.1 - 7.4e-07 28.6 0.2 1.3e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain zf-H2C2_2 PF13465.1 KFO94904.1 - 2e-11 43.6 8.4 1.5e-09 37.6 0.9 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94904.1 - 1.7e-10 40.6 7.3 1.9e-07 31.0 0.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94904.1 - 3.9e-08 33.0 5.5 4.2e-06 26.7 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO94904.1 - 1.3e-06 28.3 1.0 0.00088 19.3 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO94904.1 - 1.5e-06 27.8 5.5 0.0032 17.2 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFO94904.1 - 0.00077 19.5 0.7 0.0021 18.1 0.5 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KFO94904.1 - 0.0012 18.7 2.2 0.043 13.7 1.6 2.1 1 1 0 1 1 1 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO94904.1 - 0.0041 16.9 2.6 0.0066 16.2 1.8 1.4 1 1 0 1 1 1 1 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFO94904.1 - 0.0043 16.4 8.5 0.16 11.4 0.3 2.1 2 0 0 2 2 2 2 zinc-ribbon domain zf-BED PF02892.10 KFO94904.1 - 0.0045 16.7 1.9 0.55 10.0 0.0 2.1 1 1 1 2 2 2 2 BED zinc finger Prok-RING_1 PF14446.1 KFO94904.1 - 0.0065 16.1 0.3 1.5 8.5 0.1 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DUF2256 PF10013.4 KFO94904.1 - 0.01 15.5 2.5 0.25 11.1 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF329 PF03884.9 KFO94904.1 - 0.014 14.9 0.7 0.65 9.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF329) LIM PF00412.17 KFO94904.1 - 0.015 15.3 0.5 0.023 14.7 0.3 1.4 1 1 0 1 1 1 0 LIM domain DZR PF12773.2 KFO94904.1 - 0.02 14.7 0.8 0.033 14.0 0.6 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-met PF12874.2 KFO94904.1 - 0.02 15.0 3.5 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-ISL3 PF14690.1 KFO94904.1 - 0.027 14.5 3.4 1.8 8.6 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 C1_1 PF00130.17 KFO94904.1 - 0.027 14.1 0.2 0.058 13.1 0.1 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-trcl PF13451.1 KFO94904.1 - 0.031 13.9 0.2 0.031 13.9 0.1 1.8 2 0 0 2 2 2 0 Probable zinc-binding domain zinc_ribbon_5 PF13719.1 KFO94904.1 - 0.043 13.3 2.7 0.52 9.9 1.9 2.0 1 1 0 1 1 1 0 zinc-ribbon domain CpXC PF14353.1 KFO94904.1 - 0.053 13.4 0.6 2.7 7.9 0.4 2.0 1 1 0 1 1 1 0 CpXC protein PyrI_C PF02748.10 KFO94904.1 - 0.055 12.9 0.2 5.2 6.5 0.0 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain UPF0547 PF10571.4 KFO94904.1 - 0.055 13.1 4.2 1.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 YhfH PF14149.1 KFO94904.1 - 0.07 12.9 1.8 0.57 10.0 0.2 2.1 2 0 0 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.1 KFO94904.1 - 0.08 12.1 9.0 1.1 8.5 1.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2321 PF10083.4 KFO94904.1 - 0.088 12.2 0.8 0.1 12.0 0.6 1.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn_ribbon_recom PF13408.1 KFO94904.1 - 0.098 12.9 2.5 8.1 6.8 2.2 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2HC_2 PF13913.1 KFO94904.1 - 0.12 12.1 6.8 0.63 9.7 0.4 2.3 2 1 0 2 2 2 0 zinc-finger of a C2HC-type HNH PF01844.18 KFO94904.1 - 0.14 12.0 2.3 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 HNH endonuclease zf-IS66 PF13005.2 KFO94904.1 - 0.15 12.0 1.1 3.6 7.6 0.8 2.1 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-AN1 PF01428.11 KFO94904.1 - 0.15 11.9 4.2 0.26 11.2 0.2 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger XPA_N PF01286.13 KFO94904.1 - 0.16 11.6 3.7 0.38 10.4 0.3 2.1 2 0 0 2 2 2 0 XPA protein N-terminal TFIIS_C PF01096.13 KFO94904.1 - 0.16 11.6 3.3 0.64 9.7 0.3 2.2 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) IBR PF01485.16 KFO94904.1 - 0.16 11.8 1.4 0.39 10.6 1.0 1.7 1 1 0 1 1 1 0 IBR domain zf-CCHC_5 PF14787.1 KFO94904.1 - 0.17 11.3 6.0 1.2 8.7 0.5 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Nudix_N_2 PF14803.1 KFO94904.1 - 0.2 11.3 1.6 6.3 6.5 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_4 PF13717.1 KFO94904.1 - 0.2 11.3 4.6 0.3 10.7 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Cys_rich_CPXG PF14255.1 KFO94904.1 - 0.21 11.4 0.6 0.75 9.6 0.1 1.9 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-CHCC PF10276.4 KFO94904.1 - 0.34 10.7 6.2 3.5 7.5 1.3 2.1 2 0 0 2 2 2 0 Zinc-finger domain zf-RING_3 PF14369.1 KFO94904.1 - 0.38 10.7 8.0 4.8 7.2 1.7 2.3 2 1 0 2 2 2 0 zinc-finger OrfB_Zn_ribbon PF07282.6 KFO94904.1 - 0.4 10.3 1.7 1.1 9.0 1.2 1.7 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 KFO94904.1 - 0.42 10.1 1.9 0.76 9.2 0.0 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.7 KFO94904.1 - 0.52 9.6 3.3 8.1 5.8 0.3 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-H2C2_5 PF13909.1 KFO94904.1 - 0.86 9.9 5.0 5.8 7.3 0.5 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF164 PF02591.10 KFO94904.1 - 1.8 8.4 3.6 2.2 8.1 0.1 2.0 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-C2H2_3 PF13878.1 KFO94904.1 - 2.6 7.6 5.0 9.5 5.8 0.2 2.4 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF1610 PF07754.6 KFO94904.1 - 3 8.0 7.0 2.6 8.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) ELM2 PF01448.19 KFO94905.1 - 5.3e-05 23.7 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.26 KFO94905.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain RRM_1 PF00076.17 KFO94906.1 - 1.1e-33 114.6 0.1 1.9e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO94906.1 - 3.3e-26 91.0 0.0 1.9e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO94906.1 - 1.2e-17 63.4 0.1 4.1e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3791 PF12668.2 KFO94906.1 - 0.0011 18.5 0.5 0.21 11.2 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3791) Calcipressin PF04847.7 KFO94906.1 - 0.0052 16.3 0.0 0.042 13.4 0.0 1.9 1 1 1 2 2 2 1 Calcipressin RNA_bind PF08675.6 KFO94906.1 - 0.022 14.7 0.0 2.7 8.0 0.0 2.1 1 1 0 2 2 2 0 RNA binding domain DbpA PF03880.10 KFO94906.1 - 0.053 13.1 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 DbpA RNA binding domain zf-H2C2_2 PF13465.1 KFO94907.1 - 2.2e-11 43.4 9.9 4.3e-06 26.7 0.6 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFO94907.1 - 2.6e-09 36.8 16.4 8.7e-05 22.6 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFO94907.1 - 1.1e-07 31.5 12.3 0.0034 17.2 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFO94907.1 - 0.00058 20.0 13.7 0.052 13.8 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger Prok-RING_1 PF14446.1 KFO94907.1 - 0.0017 18.0 5.3 0.13 12.0 0.1 3.0 1 1 1 3 3 3 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KFO94907.1 - 0.0054 16.4 5.4 0.031 14.0 0.4 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.7 KFO94907.1 - 0.0062 16.5 2.9 0.0062 16.5 2.0 2.1 1 1 1 2 2 2 1 TFIIH C1-like domain zf-AN1 PF01428.11 KFO94907.1 - 0.0063 16.3 6.5 4.8 7.1 0.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger XPA_N PF01286.13 KFO94907.1 - 0.0093 15.6 7.6 0.16 11.6 0.1 3.1 3 0 0 3 3 3 1 XPA protein N-terminal Yippee-Mis18 PF03226.9 KFO94907.1 - 0.018 15.0 3.3 0.027 14.4 2.3 1.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RING_3 PF14369.1 KFO94907.1 - 0.02 14.8 6.8 0.087 12.8 0.1 3.1 3 0 0 3 3 3 0 zinc-finger zf-C2H2_jaz PF12171.3 KFO94907.1 - 0.037 14.1 1.0 0.037 14.1 0.7 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFO94907.1 - 0.038 14.0 1.4 0.038 14.0 1.0 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KFO94907.1 - 0.048 13.6 11.1 0.72 9.8 2.9 2.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-C4_ClpX PF06689.8 KFO94907.1 - 0.051 13.1 1.8 2.2 7.8 0.5 2.2 2 0 0 2 2 2 0 ClpX C4-type zinc finger Pox_A3L PF05288.6 KFO94907.1 - 0.067 12.9 2.0 2.9 7.6 0.0 2.4 3 0 0 3 3 2 0 Poxvirus A3L Protein Transpos_assoc PF13963.1 KFO94907.1 - 0.096 12.6 3.4 1.1 9.3 0.8 2.3 1 1 1 2 2 2 0 Transposase-associated domain DNA_RNApol_7kD PF03604.8 KFO94907.1 - 0.21 11.1 3.2 13 5.3 0.1 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.2 KFO94907.1 - 0.23 11.2 10.4 0.22 11.3 2.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain LIM PF00412.17 KFO94907.1 - 0.27 11.3 7.2 4 7.5 0.1 2.6 1 1 0 2 2 2 0 LIM domain zf-H2C2_5 PF13909.1 KFO94907.1 - 0.4 11.0 14.4 1.7 9.0 0.7 3.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain RRN7 PF11781.3 KFO94907.1 - 0.45 10.0 5.9 19 4.8 0.3 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 KFO94907.1 - 0.45 10.3 6.9 0.12 12.1 0.9 2.1 1 1 1 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 KFO94907.1 - 0.51 10.1 4.7 27 4.6 0.1 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon C1_3 PF07649.7 KFO94907.1 - 0.68 10.0 9.6 1.1 9.3 0.2 3.3 3 1 0 3 3 3 0 C1-like domain DUF35_N PF12172.3 KFO94907.1 - 0.69 9.9 0.2 0.69 9.9 0.1 2.7 3 0 0 3 3 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_ribbon_recom PF13408.1 KFO94907.1 - 0.8 10.0 5.1 2 8.7 3.5 1.7 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-trcl PF13451.1 KFO94907.1 - 0.82 9.3 11.4 2.2 7.9 0.2 3.1 2 1 0 3 3 3 0 Probable zinc-binding domain zinc_ribbon_4 PF13717.1 KFO94907.1 - 1.1 9.0 8.6 11 5.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KFO94907.1 - 1.1 8.6 4.4 14 5.0 0.0 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding zf-Paramyx-P PF13008.2 KFO94907.1 - 1.5 8.0 5.9 11 5.3 0.0 2.9 3 0 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein zinc-ribbons_6 PF07191.7 KFO94907.1 - 1.5 8.6 6.2 2.9 7.7 1.3 2.4 1 1 1 2 2 2 0 zinc-ribbons c-SKI_SMAD_bind PF08782.5 KFO94907.1 - 1.6 8.8 4.7 4.7 7.4 3.2 1.8 1 1 0 1 1 1 0 c-SKI Smad4 binding domain TFIIS_C PF01096.13 KFO94907.1 - 1.8 8.2 9.0 19 4.9 0.0 3.3 3 1 0 3 3 3 0 Transcription factor S-II (TFIIS) Sgf11 PF08209.6 KFO94907.1 - 1.9 7.8 8.4 3.3 7.0 0.2 3.1 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-met PF12874.2 KFO94907.1 - 2.1 8.7 9.0 1.5 9.1 0.1 2.7 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.1 KFO94907.1 - 2.2 7.9 9.6 12 5.5 0.1 3.0 2 1 0 2 2 2 0 zinc-ribbon domain DUF1272 PF06906.6 KFO94907.1 - 2.7 7.9 5.7 4.6 7.1 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zinc_ribbon_2 PF13240.1 KFO94907.1 - 2.7 7.5 6.6 3.9 7.1 1.1 2.8 2 1 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 KFO94907.1 - 3.1 7.4 6.0 21 4.8 4.2 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_4 PF14570.1 KFO94907.1 - 3.2 7.4 6.9 6.6 6.3 2.2 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KFO94907.1 - 4 7.2 8.1 4.3e+02 0.7 5.6 2.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-DNL PF05180.7 KFO94907.1 - 4.9 6.9 7.0 1.2 8.9 1.0 2.1 1 1 1 2 2 2 0 DNL zinc finger zf-RING_2 PF13639.1 KFO94907.1 - 4.9 7.0 7.2 3 7.7 2.2 2.2 2 1 0 2 2 2 0 Ring finger domain zf-IS66 PF13005.2 KFO94907.1 - 5.1 7.1 8.9 4 7.4 0.1 2.5 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-LYAR PF08790.6 KFO94907.1 - 5.7 6.7 15.1 0.89 9.3 0.2 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger A2L_zn_ribbon PF08792.5 KFO94907.1 - 5.8 6.4 6.3 19 4.8 0.0 3.0 3 0 0 3 3 3 0 A2L zinc ribbon domain DUF2072 PF09845.4 KFO94907.1 - 5.9 6.8 5.9 17 5.3 4.0 2.0 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) CpXC PF14353.1 KFO94907.1 - 6.2 6.7 6.8 4.7 7.2 0.8 2.7 1 1 1 2 2 2 0 CpXC protein IBR PF01485.16 KFO94907.1 - 6.8 6.6 9.3 12 5.8 2.4 2.6 1 1 2 3 3 3 0 IBR domain zf-C2H2 PF00096.21 KFO94908.1 - 1.6e-10 40.6 9.9 3.3e-07 30.2 0.4 2.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO94908.1 - 1.6e-07 31.1 6.6 8.8e-05 22.5 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO94908.1 - 3.2e-06 27.1 14.2 3.4e-06 27.0 0.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-RING_3 PF14369.1 KFO94908.1 - 0.00061 19.7 1.7 0.18 11.8 0.2 2.1 2 0 0 2 2 2 2 zinc-finger zf-Di19 PF05605.7 KFO94908.1 - 0.034 14.2 0.8 0.079 13.0 0.5 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.1 KFO94908.1 - 0.049 12.8 0.4 0.049 12.8 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 KFO94908.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_2 PF13240.1 KFO94908.1 - 0.064 12.7 3.3 0.33 10.5 2.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-TRAF PF02176.13 KFO94908.1 - 0.093 13.1 0.6 0.1 13.0 0.4 1.1 1 0 0 1 1 1 0 TRAF-type zinc finger zf-BED PF02892.10 KFO94908.1 - 0.11 12.2 1.0 0.19 11.4 0.7 1.5 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 KFO94908.1 - 4.3 7.7 11.8 0.26 11.5 0.5 3.0 2 2 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 KFO94908.1 - 4.5 7.0 7.2 0.44 10.2 0.9 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type V-set PF07686.12 KFO94909.1 - 5.2e-06 26.3 0.0 5.8e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Synaptobrevin PF00957.16 KFO94910.1 - 1.9e-22 78.6 0.5 2e-22 78.5 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin Seryl_tRNA_N PF02403.17 KFO94910.1 - 0.093 12.7 0.3 0.1 12.6 0.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Lectin_C PF00059.16 KFO94911.1 - 5.1e-05 23.8 0.8 0.00019 22.0 0.0 1.8 1 1 1 2 2 2 1 Lectin C-type domain Chordopox_A33R PF05966.7 KFO94911.1 - 0.02 13.6 0.0 0.02 13.6 0.0 1.0 1 0 0 1 1 1 0 Chordopoxvirus A33R protein PAP_central PF04928.12 KFO94912.1 - 0.056 12.2 0.2 0.058 12.2 0.1 1.0 1 0 0 1 1 1 0 Poly(A) polymerase central domain Toxin_4 PF00706.12 KFO94912.1 - 0.09 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Anenome neurotoxin Dymeclin PF09742.4 KFO94913.1 - 4e-13 48.3 1.2 4.1e-13 48.3 0.8 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF4512 PF14975.1 KFO94915.1 - 1.7e-17 63.9 2.7 1.9e-17 63.8 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Clat_adaptor_s PF01217.15 KFO94916.1 - 1.4e-17 63.7 0.3 1.5e-17 63.6 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Tautomerase PF01361.16 KFO94916.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Tautomerase enzyme Trypsin PF00089.21 KFO94917.1 - 2.4e-14 53.4 0.0 2.5e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin SET PF00856.23 KFO94918.1 - 9.9e-16 58.4 0.0 1e-15 58.4 0.0 1.0 1 0 0 1 1 1 1 SET domain HAD_2 PF13419.1 KFO94919.1 - 1e-07 32.3 0.0 1.1e-07 32.2 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase KbaA PF14089.1 KFO94920.1 - 0.021 14.3 1.0 0.023 14.2 0.7 1.1 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation Col_cuticle_N PF01484.12 KFO94920.1 - 0.088 12.5 3.0 2.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Nematode cuticle collagen N-terminal domain zf-C2H2_4 PF13894.1 KFO94921.1 - 7.1e-05 22.8 3.6 0.1 12.9 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO94921.1 - 0.0013 18.9 5.1 0.025 14.9 0.5 2.5 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFO94921.1 - 0.0016 18.5 1.5 0.9 9.7 0.1 2.7 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFO94921.1 - 0.0058 16.7 1.7 1.1 9.3 0.2 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFO94921.1 - 0.0097 16.0 3.7 1.1 9.6 0.1 2.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KFO94921.1 - 0.023 14.9 9.6 0.024 14.9 1.8 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Baculo_IE-1 PF05290.6 KFO94921.1 - 0.057 13.1 1.2 0.057 13.1 0.8 1.5 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-Di19 PF05605.7 KFO94921.1 - 0.078 13.1 9.0 0.39 10.8 6.5 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding OTT_1508_deam PF14441.1 KFO94921.1 - 0.19 11.5 2.2 1.7 8.4 0.3 2.0 1 1 1 2 2 2 0 OTT_1508-like deaminase CHCH PF06747.8 KFO94922.1 - 0.0006 19.6 8.4 0.00082 19.2 5.8 1.2 1 0 0 1 1 1 1 CHCH domain DB PF01682.14 KFO94922.1 - 0.0052 16.7 1.3 0.006 16.5 0.9 1.1 1 0 0 1 1 1 1 DB module Cmc1 PF08583.5 KFO94922.1 - 0.0078 15.9 4.8 0.21 11.3 0.7 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KFO94922.1 - 0.02 14.8 1.4 0.026 14.5 1.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 KFO94922.1 - 0.04 13.9 2.7 0.049 13.6 1.8 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) NDUF_B7 PF05676.8 KFO94922.1 - 0.058 12.8 1.5 0.065 12.6 1.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3128 PF11326.3 KFO94922.1 - 0.067 13.3 1.6 2.6 8.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) GCK PF07802.6 KFO94922.1 - 0.096 12.8 0.4 0.1 12.7 0.3 1.1 1 0 0 1 1 1 0 GCK domain Fer2_BFD PF04324.10 KFO94922.1 - 0.76 9.8 3.0 12 6.0 2.0 2.0 1 1 0 1 1 1 0 BFD-like [2Fe-2S] binding domain ANF_receptor PF01094.23 KFO94923.1 - 6.8e-09 34.9 0.0 7.6e-09 34.8 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region BAF PF02961.9 KFO94924.1 - 6.9e-24 83.9 1.1 7.4e-24 83.8 0.7 1.0 1 0 0 1 1 1 1 Barrier to autointegration factor Defensin_beta PF00711.14 KFO94926.1 - 7.4e-10 38.5 8.6 8.1e-10 38.4 6.0 1.1 1 0 0 1 1 1 1 Beta defensin Polysacc_synt_4 PF04669.8 KFO94927.1 - 0.0097 15.2 0.0 0.0098 15.2 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis Ras PF00071.17 KFO94928.1 - 1.3e-41 141.6 0.0 1.4e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO94928.1 - 1.4e-12 48.1 0.0 2.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFO94928.1 - 5.4e-07 29.2 0.0 1.1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFO94928.1 - 1.4e-05 24.4 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 KFO94928.1 - 0.0089 15.3 0.0 0.0098 15.1 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B COG2 PF06148.6 KFO94929.1 - 0.0026 17.6 0.8 0.0028 17.5 0.6 1.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4455 PF14643.1 KFO94929.1 - 0.013 14.1 0.3 0.013 14.1 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Spc7 PF08317.6 KFO94929.1 - 0.019 13.6 0.6 0.02 13.5 0.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF713 PF05218.9 KFO94929.1 - 0.023 14.4 0.1 0.023 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Sec2p PF06428.6 KFO94929.1 - 0.046 13.5 1.8 0.055 13.3 1.2 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4599 PF15371.1 KFO94929.1 - 0.094 12.7 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) BRX_N PF13713.1 KFO94929.1 - 0.096 12.1 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Pox_A_type_inc PF04508.7 KFO94929.1 - 0.099 12.4 0.4 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat AGTRAP PF06396.6 KFO94930.1 - 3.1e-23 82.2 0.1 3.3e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Tubulin PF00091.20 KFO94931.1 - 2.1e-10 40.7 0.0 2.2e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain GPP34 PF05719.6 KFO94932.1 - 9.7e-16 58.4 0.3 1e-15 58.3 0.2 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.8 KFO94932.1 - 0.044 13.2 0.1 0.071 12.5 0.1 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF882) C1-set PF07654.10 KFO94933.1 - 1.7e-26 92.0 0.2 1.8e-26 91.9 0.2 1.0 1 0 0 1 1 1 1 Immunoglobulin C1-set domain ig PF00047.20 KFO94933.1 - 0.0041 17.2 0.2 0.0061 16.6 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFO94933.1 - 0.0073 16.1 0.0 0.0079 16.0 0.0 1.1 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFO94933.1 - 0.012 15.4 0.1 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain Marek_A PF02124.10 KFO94933.1 - 0.046 13.1 0.1 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 Marek's disease glycoprotein A PTH2 PF01981.11 KFO94934.1 - 2.8e-50 168.8 0.0 3.2e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2000 PF09391.5 KFO94934.1 - 0.0066 16.1 0.1 0.074 12.7 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2000) DUF4610 PF15384.1 KFO94934.1 - 0.1 12.0 0.1 0.24 10.8 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4610) Rsm22 PF09243.5 KFO94934.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 zf-RING_2 PF13639.1 KFO94935.1 - 2.3e-09 36.9 11.9 4.4e-09 36.0 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFO94935.1 - 6.6e-07 28.9 11.1 6.6e-07 28.9 7.7 1.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFO94935.1 - 3.8e-06 26.8 12.3 8e-06 25.7 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO94935.1 - 2e-05 24.1 9.5 4.3e-05 23.1 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFO94935.1 - 2.7e-05 23.7 5.4 2.7e-05 23.7 3.8 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFO94935.1 - 4e-05 23.1 11.6 9e-05 22.0 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFO94935.1 - 0.00087 19.1 7.4 0.0013 18.5 4.5 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_4 PF14570.1 KFO94935.1 - 0.0022 17.5 7.5 0.0044 16.5 5.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain GAGA PF09237.6 KFO94935.1 - 0.028 14.0 1.9 3.5 7.3 0.1 2.3 2 0 0 2 2 2 0 GAGA factor FYVE_2 PF02318.11 KFO94935.1 - 0.05 13.4 4.0 0.042 13.7 1.9 1.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.1 KFO94935.1 - 0.13 12.1 14.8 1.8 8.4 10.3 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFO94935.1 - 2.5 8.2 7.8 6.1 7.0 5.4 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 KFO94935.1 - 5.6 6.5 12.6 28 4.3 8.8 2.2 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 KFO94935.1 - 7.3 6.4 9.8 40 4.0 0.0 3.0 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Bile_Hydr_Trans PF04775.9 KFO94936.1 - 2.3e-32 111.3 0.0 2.6e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region BAMBI PF06211.7 KFO94937.1 - 0.009 15.9 0.5 0.011 15.6 0.3 1.2 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain UPAR_LY6 PF00021.16 KFO94937.1 - 0.017 15.5 0.5 0.023 15.1 0.3 1.2 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Activin_recp PF01064.18 KFO94937.1 - 0.11 13.1 1.9 0.18 12.4 1.3 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain Herpes_LAMP2 PF06126.6 KFO94937.1 - 0.14 10.5 1.5 0.15 10.4 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 p450 PF00067.17 KFO94938.1 - 2.8e-13 49.2 0.1 2.8e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_7 PF13499.1 KFO94942.1 - 1.7e-10 40.9 1.6 5.3e-09 36.0 1.1 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFO94942.1 - 7.2e-10 37.9 2.9 3e-08 32.8 0.6 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KFO94942.1 - 6e-09 34.5 9.5 2.4e-08 32.6 1.1 3.9 5 0 0 5 5 5 1 EF hand EF-hand_5 PF13202.1 KFO94942.1 - 6.6e-06 25.2 1.2 6.6e-06 25.2 0.9 2.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 KFO94942.1 - 2.2e-05 23.9 7.1 0.00013 21.5 0.1 3.4 3 2 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO94942.1 - 0.13 12.3 0.2 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region GF_recep_IV PF14843.1 KFO94943.1 - 0.069 12.7 0.7 0.076 12.6 0.5 1.0 1 0 0 1 1 1 0 Growth factor receptor domain IV Peptidase_M76 PF09768.4 KFO94943.1 - 0.14 11.5 0.2 0.15 11.5 0.2 1.1 1 0 0 1 1 1 0 Peptidase M76 family FRG2 PF15315.1 KFO94944.1 - 0.14 12.1 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Neur PF00064.13 KFO94945.1 - 0.017 13.2 0.0 0.019 13.0 0.0 1.0 1 0 0 1 1 1 0 Neuraminidase KASH PF10541.4 KFO94945.1 - 0.17 11.7 1.1 0.28 11.0 0.8 1.5 1 1 0 1 1 1 0 Nuclear envelope localisation domain Proteasome PF00227.21 KFO94946.1 - 7.5e-15 54.7 0.0 8e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 KFO94948.1 - 1.7e-06 27.4 0.0 1.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Snapin_Pallidin PF14712.1 KFO94950.1 - 0.033 14.5 4.4 0.037 14.3 3.0 1.2 1 0 0 1 1 1 0 Snapin/Pallidin 7tm_1 PF00001.16 KFO94951.1 - 8.9e-22 77.4 3.5 1e-21 77.2 2.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFO94951.1 - 0.04 13.7 0.6 0.04 13.7 0.4 2.0 2 1 1 3 3 3 0 Olfactory receptor SH2 PF00017.19 KFO94952.1 - 1.4e-06 27.9 0.1 2.1e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 SH2 domain HIG_1_N PF04588.8 KFO94953.1 - 2.9e-16 58.9 2.6 3.2e-16 58.7 1.8 1.0 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF998 PF06197.8 KFO94953.1 - 0.019 14.3 0.8 0.019 14.2 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF998) LIM PF00412.17 KFO94954.1 - 2.1e-16 59.7 9.1 2.4e-16 59.5 6.3 1.0 1 0 0 1 1 1 1 LIM domain C1_4 PF07975.7 KFO94954.1 - 0.0013 18.6 5.8 0.0027 17.6 4.0 1.5 1 0 0 1 1 1 1 TFIIH C1-like domain Vps39_2 PF10367.4 KFO94954.1 - 0.019 15.1 0.9 0.019 15.1 0.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Mut7-C PF01927.11 KFO94954.1 - 0.024 14.5 1.3 0.029 14.3 0.9 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain Churchill PF06573.6 KFO94954.1 - 0.094 12.7 3.0 0.13 12.2 2.0 1.3 1 1 0 1 1 1 0 Churchill protein Zn_Tnp_IS1595 PF12760.2 KFO94954.1 - 0.11 12.3 3.5 0.23 11.2 2.4 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Arc_trans_TRASH PF08394.5 KFO94954.1 - 0.16 12.1 3.3 0.4 10.8 2.3 1.7 1 1 0 1 1 1 0 Archaeal TRASH domain C1_1 PF00130.17 KFO94954.1 - 0.91 9.2 7.3 1.2 8.9 3.9 2.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Endonuclease_7 PF02945.10 KFO94954.1 - 1 9.0 5.9 0.73 9.5 0.8 2.1 1 1 1 2 2 2 0 Recombination endonuclease VII Trypsin PF00089.21 KFO94955.1 - 7.3e-18 64.9 1.5 7.8e-18 64.8 1.0 1.0 1 0 0 1 1 1 1 Trypsin Folate_carrier PF01770.13 KFO94958.1 - 1.6e-103 346.4 4.6 1.8e-103 346.2 3.2 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 KFO94958.1 - 9.1e-10 37.7 5.5 1.1e-09 37.4 3.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily dUTPase PF00692.14 KFO94959.1 - 1.8e-23 82.4 0.1 2.4e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFO94959.1 - 0.00045 20.0 0.1 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KFO94959.1 - 0.13 12.7 1.3 0.35 11.4 0.1 2.2 3 0 0 3 3 3 0 Aspartyl protease Trypsin PF00089.21 KFO94960.1 - 2.8e-17 63.0 2.6 3e-17 62.9 1.8 1.0 1 0 0 1 1 1 1 Trypsin Pkinase PF00069.20 KFO94961.1 - 4.9e-06 25.8 0.0 5.2e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Filament PF00038.16 KFO94962.1 - 6.3e-48 163.8 5.1 6.9e-48 163.7 3.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.7 KFO94962.1 - 0.0066 16.2 2.2 0.013 15.2 0.7 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) Prefoldin PF02996.12 KFO94962.1 - 0.01 15.4 5.0 0.87 9.2 0.5 3.0 2 1 1 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 KFO94962.1 - 0.02 14.7 3.0 1.5 8.6 1.9 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 KFO94962.1 - 0.031 13.6 2.7 0.042 13.2 1.9 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Transposase_22 PF02994.9 KFO94962.1 - 0.05 12.1 3.7 0.062 11.7 2.6 1.0 1 0 0 1 1 1 0 L1 transposable element Reo_sigmaC PF04582.7 KFO94962.1 - 0.057 12.5 0.3 0.068 12.3 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4407 PF14362.1 KFO94962.1 - 0.076 11.9 4.0 0.1 11.5 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TBPIP PF07106.8 KFO94962.1 - 0.1 12.1 4.9 0.06 12.8 1.6 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) T2SM PF04612.7 KFO94962.1 - 0.11 12.3 2.1 4.8 6.9 1.6 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M SDH_beta PF03315.10 KFO94962.1 - 0.13 12.2 0.2 0.23 11.5 0.1 1.4 1 1 0 1 1 1 0 Serine dehydratase beta chain Tropomyosin_1 PF12718.2 KFO94962.1 - 0.13 12.0 6.3 0.13 12.1 3.6 1.5 1 1 0 1 1 1 0 Tropomyosin like TPR_MLP1_2 PF07926.7 KFO94962.1 - 0.15 11.7 10.3 0.72 9.6 7.1 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Lzipper-MIP1 PF14389.1 KFO94962.1 - 0.16 12.0 3.5 0.25 11.4 1.4 2.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Atg14 PF10186.4 KFO94962.1 - 0.17 10.8 4.3 0.23 10.3 3.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KFO94962.1 - 0.37 8.6 2.1 0.41 8.4 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KFO94962.1 - 0.48 9.0 8.0 0.28 9.7 3.9 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 KFO94962.1 - 0.5 10.2 9.7 3.4 7.5 5.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 KFO94962.1 - 0.5 8.7 4.4 0.74 8.1 3.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 KFO94962.1 - 0.66 9.9 5.3 9.3 6.2 0.0 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.3 KFO94962.1 - 0.73 9.6 5.4 1.1 9.0 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Mod_r PF07200.8 KFO94962.1 - 0.76 9.6 7.7 3.9 7.3 5.4 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein COMP PF11598.3 KFO94962.1 - 0.82 9.7 11.7 1.4 9.0 0.4 3.2 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein FlxA PF14282.1 KFO94962.1 - 1.3 9.0 9.4 1.1 9.2 3.8 2.4 1 1 1 2 2 2 0 FlxA-like protein FUSC PF04632.7 KFO94962.1 - 1.3 7.3 3.6 2.2 6.5 2.5 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Bap31 PF05529.7 KFO94962.1 - 1.8 7.9 5.2 1.8 7.9 1.3 1.9 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like SlyX PF04102.7 KFO94962.1 - 2.1 8.7 11.1 5.4 7.4 1.2 3.1 2 1 1 3 3 3 0 SlyX CENP-F_leu_zip PF10473.4 KFO94962.1 - 2.5 7.9 10.4 1.1 9.1 4.7 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KFO94962.1 - 2.6 6.9 8.7 3.2 6.7 6.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_A_type_inc PF04508.7 KFO94962.1 - 3.8 7.5 7.7 4.4 7.3 0.8 4.0 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat IncA PF04156.9 KFO94962.1 - 5.8 6.4 12.5 13 5.2 8.6 1.6 1 1 0 1 1 1 0 IncA protein Trypsin PF00089.21 KFO94964.1 - 4.1e-19 69.0 1.2 4.6e-19 68.8 0.8 1.0 1 0 0 1 1 1 1 Trypsin Homeobox PF00046.24 KFO94966.1 - 4.4e-12 45.4 1.1 5.2e-12 45.2 0.8 1.1 1 0 0 1 1 1 1 Homeobox domain SSFA2_C PF14723.1 KFO94966.1 - 0.1 12.3 0.3 0.13 12.0 0.2 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus zf-RING_2 PF13639.1 KFO94967.1 - 6.7e-05 22.6 10.8 6.7e-05 22.6 7.5 3.3 2 1 0 2 2 2 1 Ring finger domain zf-HC5HC2H PF13771.1 KFO94967.1 - 0.0035 17.4 11.6 0.0035 17.4 8.0 3.6 2 2 0 2 2 2 1 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.1 KFO94967.1 - 0.019 14.9 5.3 0.019 14.9 3.7 4.4 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO94967.1 - 0.02 14.5 8.7 0.02 14.5 6.0 3.6 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Cys_rich_KTR PF14205.1 KFO94967.1 - 0.081 12.3 0.6 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Cysteine-rich KTR PHD PF00628.24 KFO94967.1 - 2.4 7.8 23.2 0.82 9.4 4.8 3.6 3 1 1 4 4 4 0 PHD-finger zf-rbx1 PF12678.2 KFO94967.1 - 3.4 7.8 20.4 12 6.0 3.5 2.8 1 1 2 3 3 3 0 RING-H2 zinc finger DUF1664 PF07889.7 KFO94968.1 - 0.0015 18.2 2.1 0.0017 18.1 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF3166 PF11365.3 KFO94968.1 - 0.0034 17.8 0.8 0.004 17.5 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3166) TMCO5 PF14992.1 KFO94968.1 - 0.011 14.8 3.4 0.011 14.8 2.4 1.0 1 0 0 1 1 1 0 TMCO5 family DUF904 PF06005.7 KFO94968.1 - 0.013 15.7 1.4 0.013 15.7 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 KFO94968.1 - 0.018 15.4 2.1 0.02 15.3 1.4 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 KFO94968.1 - 0.041 13.3 2.7 0.061 12.8 1.9 1.4 1 1 0 1 1 1 0 Septum formation initiator Sec8_exocyst PF04048.9 KFO94968.1 - 0.043 13.4 1.7 0.054 13.1 1.2 1.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF342 PF03961.8 KFO94968.1 - 0.046 12.1 2.8 0.05 12.0 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Bap31 PF05529.7 KFO94968.1 - 0.048 13.1 3.2 0.056 12.9 2.2 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF2968 PF11180.3 KFO94968.1 - 0.066 12.5 0.7 0.067 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Prefoldin_2 PF01920.15 KFO94968.1 - 0.074 12.8 5.5 0.089 12.5 3.8 1.1 1 0 0 1 1 1 0 Prefoldin subunit DUF771 PF05595.6 KFO94968.1 - 0.076 12.9 1.6 0.13 12.2 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF771) TMF_DNA_bd PF12329.3 KFO94968.1 - 0.081 12.7 6.6 0.12 12.2 4.6 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SelB-wing_3 PF09107.6 KFO94968.1 - 0.087 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix HTH_11 PF08279.7 KFO94968.1 - 0.098 12.3 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 HTH domain HR1 PF02185.11 KFO94968.1 - 0.1 12.3 4.2 0.12 12.1 2.9 1.2 1 0 0 1 1 1 0 Hr1 repeat Rad9_Rad53_bind PF08605.5 KFO94968.1 - 0.1 12.4 0.1 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Atg14 PF10186.4 KFO94968.1 - 0.21 10.5 3.1 0.21 10.4 2.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFO94968.1 - 0.24 10.9 3.4 0.24 10.9 2.4 1.0 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KFO94968.1 - 0.27 11.6 2.1 0.28 11.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3498 PF12004.3 KFO94968.1 - 0.34 9.9 2.1 0.32 10.0 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) TSC22 PF01166.13 KFO94968.1 - 0.43 10.5 2.9 0.8 9.7 0.2 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family MbeB_N PF04837.7 KFO94968.1 - 0.43 10.6 5.1 2.4 8.3 0.2 2.1 1 1 1 2 2 2 0 MbeB-like, N-term conserved region HSCB_C PF07743.8 KFO94968.1 - 0.44 11.0 3.5 0.67 10.4 2.4 1.4 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Sds3 PF08598.6 KFO94968.1 - 0.62 9.5 5.3 0.73 9.3 3.6 1.2 1 0 0 1 1 1 0 Sds3-like DUF1843 PF08898.5 KFO94968.1 - 1.4 9.0 4.4 14 5.7 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) ER_lumen_recept PF00810.13 KFO94969.1 - 1e-12 48.7 0.1 1.1e-12 48.7 0.1 1.0 1 0 0 1 1 1 1 ER lumen protein retaining receptor RVT_1 PF00078.22 KFO94970.1 - 4.1e-22 78.5 0.0 4.8e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KFO94970.1 - 0.021 13.7 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lzipper-MIP1 PF14389.1 KFO94971.1 - 0.041 14.0 13.1 0.28 11.2 2.6 3.5 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 ACR_tran PF00873.14 KFO94971.1 - 0.041 11.3 0.6 0.044 11.2 0.4 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DDE_Tnp_1_6 PF13751.1 KFO94971.1 - 0.29 11.1 2.8 5.3 7.0 0.3 2.4 2 0 0 2 2 2 0 Transposase DDE domain WD40_alt PF14077.1 KFO94971.1 - 4.1 7.1 8.8 12 5.6 0.2 3.7 3 0 0 3 3 3 0 Alternative WD40 repeat motif IncA PF04156.9 KFO94971.1 - 4.4 6.8 23.2 0.23 11.0 7.8 2.9 2 1 1 3 3 3 0 IncA protein DUF1003 PF06210.6 KFO94971.1 - 7.6 6.5 7.1 1.7 8.6 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) BBP1_C PF15272.1 KFO94971.1 - 9.7 5.6 19.4 0.044 13.3 4.6 2.3 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal 7tm_2 PF00002.19 KFO94972.1 - 3.3e-16 59.1 9.0 3.4e-16 59.0 6.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3963 PF13124.1 KFO94972.1 - 0.16 11.7 2.4 0.45 10.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) E1-E2_ATPase PF00122.15 KFO94973.1 - 1.7e-13 50.1 4.5 1.8e-13 50.0 3.1 1.0 1 0 0 1 1 1 1 E1-E2 ATPase DUF475 PF04332.10 KFO94973.1 - 0.0076 15.8 2.2 0.0093 15.5 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF475) DUF368 PF04018.8 KFO94973.1 - 0.011 14.8 2.1 0.013 14.7 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Ion_trans PF00520.26 KFO94974.1 - 0.0025 17.1 0.3 0.0026 17.0 0.2 1.0 1 0 0 1 1 1 1 Ion transport protein DUF996 PF06195.8 KFO94974.1 - 0.029 14.3 0.3 0.029 14.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF996) PsbL PF02419.12 KFO94974.1 - 9.5 5.7 11.3 14 5.2 3.2 2.5 2 1 0 2 2 2 0 PsbL protein PH PF00169.24 KFO94976.1 - 0.00016 21.8 0.0 0.00039 20.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Dor1 PF04124.7 KFO94976.1 - 0.0086 14.5 0.1 0.016 13.6 0.1 1.4 1 1 0 1 1 1 1 Dor1-like family Adeno_terminal PF02459.10 KFO94976.1 - 0.02 13.0 3.6 0.039 12.1 2.5 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Sec5 PF15469.1 KFO94976.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF4591 PF15261.1 KFO94976.1 - 0.099 12.9 1.9 0.18 12.0 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Sox_C_TAD PF12067.3 KFO94977.1 - 3.9 7.5 20.0 5.7 7.0 13.8 1.3 1 1 0 1 1 1 0 Sox C-terminal transactivation domain LRR_8 PF13855.1 KFO94978.1 - 3.5e-16 58.7 5.5 5.9e-11 41.9 0.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KFO94978.1 - 4.4e-11 41.2 6.9 0.0034 17.2 0.2 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.2 KFO94978.1 - 1e-10 40.9 6.6 5.6e-07 29.0 0.3 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT PF01462.13 KFO94978.1 - 6.6e-09 35.0 2.8 6.6e-09 35.0 2.0 2.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFO94978.1 - 2.9e-06 27.0 0.1 4.6e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO94978.1 - 1.2e-05 24.7 3.9 2.3 8.7 0.0 5.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFO94978.1 - 1.5e-05 24.5 1.4 0.59 10.3 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich repeat CLTH PF10607.4 KFO94979.1 - 8e-23 80.7 2.5 9.2e-23 80.5 1.8 1.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain FlaF PF07309.6 KFO94979.1 - 0.0047 16.7 1.6 0.0062 16.3 1.1 1.2 1 0 0 1 1 1 1 Flagellar protein FlaF LRR_8 PF13855.1 KFO94980.1 - 6.1e-10 38.7 9.6 1.1e-07 31.4 2.1 2.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 KFO94980.1 - 7e-09 35.1 9.7 9.4e-07 28.3 2.9 3.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO94980.1 - 2.1e-07 30.0 7.6 0.05 13.6 0.5 5.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 KFO94980.1 - 4.3e-06 26.2 6.3 0.2 11.8 0.1 4.5 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 KFO94980.1 - 0.0014 18.4 10.0 3.2 8.3 0.1 4.5 5 0 0 5 5 5 3 Leucine rich repeat 7tm_4 PF13853.1 KFO94981.1 - 4.2e-39 133.6 7.0 4.2e-39 133.6 4.8 2.1 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO94981.1 - 3.5e-27 95.1 12.9 4.8e-27 94.7 8.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO94981.1 - 0.00032 19.9 8.4 0.00057 19.1 5.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Parathyroid PF01279.12 KFO94982.1 - 1.1e-21 77.3 2.8 1.5e-21 76.8 1.9 1.2 1 0 0 1 1 1 1 Parathyroid hormone family DUF4224 PF13986.1 KFO94982.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) PsbX PF06596.6 KFO94983.1 - 1.2 8.8 3.6 1.8 8.2 2.5 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) CENP-L PF13092.1 KFO94984.1 - 5.9e-36 123.6 0.0 6.8e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 SIS PF01380.17 KFO94985.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 0 SIS domain Phage_attach PF05354.6 KFO94985.1 - 0.13 11.7 0.0 0.4 10.2 0.0 1.7 1 1 1 2 2 2 0 Phage Head-Tail Attachment TIR PF01582.15 KFO94986.1 - 1.9e-35 121.3 0.1 3e-35 120.7 0.1 1.3 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.1 KFO94986.1 - 2.2e-15 56.1 22.5 1.6e-07 30.9 1.5 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KFO94986.1 - 6.7e-12 44.7 10.6 4.3e-07 29.4 0.2 4.8 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) TIR_2 PF13676.1 KFO94986.1 - 6.4e-11 42.3 0.0 2e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 TIR domain LRR_6 PF13516.1 KFO94986.1 - 6.6e-10 38.0 4.6 0.059 13.4 0.0 5.8 5 1 1 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 KFO94986.1 - 9.8e-10 37.1 7.1 0.092 12.8 0.2 6.3 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KFO94986.1 - 3.3e-06 26.3 7.5 0.48 10.8 0.1 5.9 7 0 0 7 7 7 2 Leucine rich repeat LRRCT PF01463.19 KFO94986.1 - 0.00078 19.5 0.1 0.0037 17.4 0.0 2.3 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Tmp39 PF10271.4 KFO94986.1 - 0.04 12.5 3.2 2.4 6.7 0.0 2.4 3 0 0 3 3 3 0 Putative transmembrane protein rve PF00665.21 KFO94988.1 - 7.8e-27 93.7 0.1 1.9e-26 92.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain RNase_H PF00075.19 KFO94988.1 - 2.2e-11 44.1 0.0 4.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 RNase H Integrase_Zn PF02022.14 KFO94988.1 - 2.8e-11 42.6 0.4 5.4e-11 41.7 0.3 1.5 1 0 0 1 1 1 1 Integrase Zinc binding domain DDE_Tnp_IS240 PF13610.1 KFO94988.1 - 1.1e-05 25.4 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.1 KFO94988.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RecR PF02132.10 KFO94988.1 - 0.076 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RecR protein IL1 PF00340.14 KFO94989.1 - 5e-30 103.4 0.6 6.5e-30 103.0 0.4 1.1 1 0 0 1 1 1 1 Interleukin-1 / 18 BACK PF07707.10 KFO94990.1 - 1.2e-31 108.6 1.9 9.9e-31 105.6 0.5 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFO94990.1 - 8e-20 70.1 2.6 2.1e-10 39.9 0.3 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 KFO94990.1 - 1.3e-15 56.7 0.4 2.4e-06 27.4 0.0 3.8 2 1 2 4 4 4 2 Kelch motif BTB PF00651.26 KFO94990.1 - 3.2e-14 52.8 0.1 6.2e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFO94990.1 - 4.4e-11 42.0 3.9 2.1e-06 27.2 0.1 2.9 2 1 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 KFO94990.1 - 9.8e-07 28.4 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 KFO94990.1 - 7.1e-06 26.0 0.0 0.0034 17.5 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO94990.1 - 0.00098 19.0 0.3 13 5.8 0.0 3.5 3 0 0 3 3 3 2 Kelch motif p450 PF00067.17 KFO94991.1 - 3.6e-21 75.2 0.1 4.1e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cpn10 PF00166.16 KFO94993.1 - 2.3e-14 53.1 0.1 2.4e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF3259 PF11652.3 KFO94995.1 - 2.6e-45 152.5 1.5 2.8e-45 152.3 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3259) DUF4605 PF15378.1 KFO94996.1 - 2.4e-28 97.5 7.4 3.7e-28 97.0 4.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4605) TMEM213 PF15192.1 KFO94997.1 - 5.3e-37 125.6 2.3 5.6e-37 125.6 1.6 1.0 1 0 0 1 1 1 1 TMEM213 family DnaJ PF00226.26 KFO94998.1 - 1.2e-16 60.1 1.2 1.7e-16 59.6 0.9 1.2 1 0 0 1 1 1 1 DnaJ domain GP41 PF00517.12 KFO94998.1 - 0.0022 17.5 0.0 0.0029 17.2 0.0 1.1 1 0 0 1 1 1 1 Retroviral envelope protein Sigma70_ner PF04546.8 KFO94998.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Corona_S2 PF01601.11 KFO94998.1 - 1.8 6.5 13.7 2.2 6.2 9.5 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Mito_carr PF00153.22 KFO94999.1 - 2.1e-10 40.1 0.0 2.2e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Y_phosphatase PF00102.22 KFO95000.1 - 2.1e-29 102.5 0.0 2.2e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CENP-F_N PF10481.4 KFO95001.1 - 2.5e-33 115.7 11.2 2.7e-33 115.6 7.8 1.0 1 0 0 1 1 1 1 Cenp-F N-terminal domain DUF167 PF02594.11 KFO95001.1 - 0.039 13.8 0.3 0.051 13.5 0.2 1.4 1 1 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 V-ATPase_C PF03223.10 KFO95001.1 - 0.067 12.0 1.9 0.076 11.9 1.3 1.1 1 0 0 1 1 1 0 V-ATPase subunit C SLY PF12485.3 KFO95001.1 - 0.12 12.6 1.7 0.13 12.5 1.1 1.0 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Hema_stalk PF08720.5 KFO95001.1 - 0.15 11.5 0.2 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk FlaC_arch PF05377.6 KFO95001.1 - 0.17 11.7 5.3 3.6 7.5 0.2 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.6 KFO95001.1 - 0.34 10.2 4.8 0.37 10.1 3.3 1.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.8 KFO95001.1 - 0.87 9.1 8.6 1.1 8.8 5.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KFO95001.1 - 0.96 9.2 3.8 1 9.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 KFO95001.1 - 1.2 9.1 7.9 5.4 7.0 1.6 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat bZIP_1 PF00170.16 KFO95001.1 - 2.4 8.1 7.8 0.71 9.8 1.4 2.1 1 1 1 2 2 2 0 bZIP transcription factor DUF2570 PF10828.3 KFO95001.1 - 2.5 7.7 8.4 2.7 7.6 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) HR1 PF02185.11 KFO95001.1 - 4.7 7.0 11.1 4.9 6.9 2.3 2.4 1 1 1 2 2 2 0 Hr1 repeat IncA PF04156.9 KFO95001.1 - 8.3 5.9 9.7 9.1 5.8 6.7 1.1 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 KFO95001.1 - 9.3 6.1 7.9 2.2e+02 1.7 5.5 2.3 1 1 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.10 KFO95001.1 - 9.7 5.7 9.4 10 5.6 2.0 2.1 1 1 1 2 2 2 0 Septum formation initiator C4 PF01413.14 KFO95002.1 - 4e-49 165.2 1.6 5.3e-38 129.4 0.4 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen EGF PF00008.22 KFO95002.1 - 0.32 11.0 3.3 1.7 8.6 1.0 2.4 2 1 0 2 2 2 0 EGF-like domain Toxin_16 PF07945.6 KFO95003.1 - 0.038 13.6 0.3 0.046 13.4 0.2 1.1 1 0 0 1 1 1 0 Janus-atracotoxin C1q PF00386.16 KFO95004.1 - 1.5e-38 131.6 0.0 1.8e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFO95004.1 - 2.2e-10 39.8 34.0 3.1e-10 39.4 23.5 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) zf-CCCH PF00642.19 KFO95005.1 - 1.9e-09 36.9 2.0 3.4e-09 36.1 1.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glycos_transf_1 PF00534.15 KFO95006.1 - 5.3e-38 130.1 0.0 8.3e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFO95006.1 - 4e-09 36.7 0.0 6.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFO95006.1 - 1.3e-06 28.5 0.0 3.5e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFO95006.1 - 0.0012 18.9 0.1 0.0048 17.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Actin PF00022.14 KFO95007.1 - 1.6e-38 132.2 0.0 1.7e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Actin NUC173 PF08161.7 KFO95008.1 - 0.014 14.7 0.1 0.034 13.4 0.0 1.6 1 0 0 1 1 1 0 NUC173 domain MIS13 PF08202.6 KFO95008.1 - 0.055 12.5 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family LSM PF01423.17 KFO95011.1 - 0.0023 17.4 0.1 0.0024 17.4 0.1 1.4 1 1 0 1 1 1 1 LSM domain TSSC4 PF15264.1 KFO95012.1 - 3.7e-29 101.5 0.0 1.1e-28 100.0 0.0 1.7 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 ATP-synt_C PF00137.16 KFO95013.1 - 5.7e-15 54.9 9.8 6.5e-15 54.7 6.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit C BPD_transp_2 PF02653.11 KFO95013.1 - 0.0075 15.2 1.7 0.0092 14.9 1.2 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component 7tm_4 PF13853.1 KFO95014.1 - 3.8e-39 133.7 16.1 3.8e-39 133.7 11.2 2.0 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO95014.1 - 3e-30 105.2 16.1 4e-30 104.8 11.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ig_2 PF13895.1 KFO95016.1 - 4e-09 36.4 0.0 4.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFO95016.1 - 1.5e-06 27.9 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain C2-set_2 PF08205.7 KFO95016.1 - 0.0022 17.8 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 KFO95016.1 - 0.01 16.3 0.0 0.035 14.6 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 KFO95016.1 - 0.15 11.9 0.0 1.1 9.1 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ribosomal_L13 PF00572.13 KFO95017.1 - 1.8e-05 24.7 0.1 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 GCV_H PF01597.14 KFO95018.1 - 2.4e-08 33.7 0.0 2.5e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein p450 PF00067.17 KFO95021.1 - 4.7e-41 140.7 0.0 5.4e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L30_N PF08079.7 KFO95022.1 - 1.6e-25 88.9 18.0 1.9e-25 88.6 12.5 1.1 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain V-set PF07686.12 KFO95024.1 - 1.8e-12 47.1 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO95024.1 - 0.0057 17.1 0.3 0.0089 16.5 0.2 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.11 KFO95024.1 - 0.012 13.8 0.0 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E I-set PF07679.11 KFO95024.1 - 0.065 13.1 0.0 0.098 12.5 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain PHD PF00628.24 KFO95025.1 - 2.9e-05 23.6 5.5 2.9e-05 23.6 3.8 1.5 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KFO95025.1 - 0.00019 20.7 5.1 0.00042 19.5 1.1 2.3 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 KFO95025.1 - 0.0027 17.4 1.3 0.0027 17.4 0.9 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 KFO95025.1 - 0.094 12.8 5.4 0.13 12.4 3.8 1.3 1 0 0 1 1 1 0 CHY zinc finger DUF2616 PF11077.3 KFO95025.1 - 0.24 10.9 2.2 0.27 10.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-DHHC PF01529.15 KFO95025.1 - 0.47 9.8 2.5 0.51 9.7 1.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DZR PF12773.2 KFO95025.1 - 0.57 10.0 4.1 1.1 9.0 2.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 KFO95025.1 - 0.67 9.7 8.9 0.26 11.0 4.1 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_3 PF07649.7 KFO95025.1 - 1.1 9.2 5.9 1.9 8.6 4.1 1.4 1 0 0 1 1 1 0 C1-like domain JmjC PF02373.17 KFO95026.1 - 1.5e-14 54.1 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KFO95026.1 - 0.014 14.8 0.0 0.014 14.8 0.0 2.2 2 1 0 2 2 2 0 Cupin domain CLASP_N PF12348.3 KFO95027.1 - 2.5e-07 30.2 0.1 2.6e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 KFO95027.1 - 0.0017 18.3 0.2 0.88 9.8 0.1 3.1 3 0 0 3 3 3 1 HEAT repeat ABC2_membrane PF01061.19 KFO95028.1 - 4.9e-19 68.3 9.9 4.9e-19 68.3 6.8 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 KFO95028.1 - 1.4e-05 24.3 6.5 1.7e-05 24.0 4.5 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 KFO95028.1 - 0.0048 15.7 4.3 0.0064 15.3 3.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein MpPF26 PF07666.6 KFO95028.1 - 2.9 7.7 6.3 0.22 11.4 0.4 2.0 2 1 0 2 2 2 0 M penetrans paralogue family 26 TSP_C PF05735.7 KFO95029.1 - 3.9e-59 199.6 4.1 4.2e-59 199.5 2.9 1.0 1 0 0 1 1 1 1 Thrombospondin C-terminal region EGF PF00008.22 KFO95030.1 - 0.0014 18.5 3.6 0.0033 17.3 2.5 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFO95030.1 - 0.0022 17.9 0.5 0.006 16.5 0.4 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF Laminin_EGF PF00053.19 KFO95030.1 - 1.9 8.4 6.9 0.35 10.8 2.4 1.7 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) SKG6 PF08693.5 KFO95030.1 - 4.1 6.7 5.5 7.1 6.0 3.8 1.4 1 1 0 1 1 1 0 Transmembrane alpha-helix domain RhoGEF PF00621.15 KFO95031.1 - 9.1e-15 54.9 0.2 1e-14 54.8 0.1 1.0 1 0 0 1 1 1 1 RhoGEF domain PMP22_Claudin PF00822.15 KFO95032.1 - 1.5e-13 50.7 3.2 1.6e-13 50.6 2.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO95032.1 - 0.00021 21.0 7.2 0.00024 20.8 5.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KFO95032.1 - 0.013 15.1 3.3 0.016 14.8 2.3 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF4013 PF13197.1 KFO95032.1 - 0.07 12.4 2.4 0.079 12.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF4231 PF14015.1 KFO95032.1 - 0.091 12.7 2.5 0.13 12.2 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF898 PF05987.8 KFO95032.1 - 0.23 10.2 2.6 0.24 10.2 1.8 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) SdpI PF13630.1 KFO95032.1 - 5.2 6.8 7.9 4.1 7.1 0.9 2.1 1 1 1 2 2 2 0 SdpI/YhfL protein family Trypsin PF00089.21 KFO95033.1 - 4e-19 69.0 0.4 4.3e-19 68.9 0.3 1.0 1 0 0 1 1 1 1 Trypsin Fumble PF03630.9 KFO95035.1 - 9.5e-47 159.4 0.1 1e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 Fumble TIR PF01582.15 KFO95036.1 - 6.8e-08 32.0 0.0 8.8e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 TIR domain DUF4342 PF14242.1 KFO95036.1 - 0.23 11.2 0.9 0.4 10.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Lipocalin_7 PF14651.1 KFO95038.1 - 1e-25 89.8 0.8 1.1e-25 89.7 0.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFO95038.1 - 2.3e-10 40.6 0.8 2.5e-10 40.5 0.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Toxin_58 PF15536.1 KFO95038.1 - 0.042 13.6 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 58 Trypsin PF00089.21 KFO95039.1 - 9.3e-18 64.6 0.0 1e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFO95039.1 - 0.0038 16.5 0.0 0.004 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) RRM_1 PF00076.17 KFO95040.1 - 5.2e-23 80.4 0.1 2.7e-20 71.7 0.0 2.6 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95040.1 - 2.6e-14 52.9 0.1 4.8e-12 45.6 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95040.1 - 2.2e-12 46.6 0.0 1.6e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KFO95041.1 - 4.1e-12 45.8 0.0 4.4e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95041.1 - 2.6e-08 33.2 0.0 3.1e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFO95041.1 - 1.3e-05 24.4 0.8 1.8e-05 23.9 0.6 1.2 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif DUF1923 PF09083.5 KFO95041.1 - 0.14 11.6 0.2 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) VGLL4 PF15245.1 KFO95042.1 - 0.054 13.3 2.9 0.064 13.0 2.0 1.1 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 ABC_tran PF00005.22 KFO95042.1 - 0.14 12.4 0.3 0.18 12.0 0.2 1.2 1 0 0 1 1 1 0 ABC transporter KH_1 PF00013.24 KFO95044.1 - 8.5e-13 47.7 0.0 1.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFO95044.1 - 8.2e-07 28.5 0.0 2.8e-06 26.8 0.0 1.9 1 1 1 2 2 2 1 KH domain KH_4 PF13083.1 KFO95044.1 - 0.0062 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 KH domain DUF4566 PF15130.1 KFO95045.1 - 6.8e-94 313.5 0.5 7.4e-94 313.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) Rtf2 PF04641.7 KFO95046.1 - 0.042 13.0 7.1 0.041 13.0 4.9 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger BLVR PF06375.6 KFO95046.1 - 0.082 12.7 12.0 0.088 12.6 8.3 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TSGP1 PF07771.6 KFO95046.1 - 0.2 11.5 5.4 0.26 11.1 3.8 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 Peptidase_S49_N PF08496.5 KFO95046.1 - 1.3 8.8 7.3 1.3 8.8 5.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.9 KFO95046.1 - 1.9 6.4 8.5 1.9 6.4 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 KFO95046.1 - 2 8.4 6.3 2.1 8.3 4.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF1682 PF07946.9 KFO95046.1 - 2.9 6.6 14.7 3.3 6.4 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PBP_sp32 PF07222.7 KFO95046.1 - 3.1 6.9 6.5 3.2 6.8 4.5 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Tbf5 PF06331.7 KFO95049.1 - 3e-20 71.7 0.1 3.2e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 TypeIII_RM_meth PF12564.3 KFO95049.1 - 0.094 12.7 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit TM1586_NiRdase PF14512.1 KFO95050.1 - 0.054 12.6 0.2 0.056 12.6 0.1 1.0 1 0 0 1 1 1 0 Putative TM nitroreductase Epimerase_Csub PF13950.1 KFO95050.1 - 0.08 12.8 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Metallophos PF00149.23 KFO95051.1 - 8.6e-31 106.8 0.1 9.5e-31 106.7 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Laminin_EGF PF00053.19 KFO95052.1 - 1.7e-12 47.0 23.5 8.2e-08 32.0 11.4 2.1 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) GCC2_GCC3 PF07699.8 KFO95052.1 - 0.0085 15.6 18.4 0.0094 15.5 5.1 2.6 1 1 0 2 2 2 2 GCC2 and GCC3 hEGF PF12661.2 KFO95052.1 - 0.081 13.0 0.5 0.081 13.0 0.4 4.7 5 0 0 5 5 5 0 Human growth factor-like EGF Mesothelin PF06060.7 KFO95053.1 - 1.7e-35 122.1 0.0 1.9e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Flavodoxin_NdrI PF07972.6 KFO95053.1 - 0.043 13.7 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 NrdI Flavodoxin like Yippee-Mis18 PF03226.9 KFO95054.1 - 3.9e-12 46.0 0.1 4.1e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NinE PF05322.6 KFO95054.1 - 0.15 11.8 1.0 0.19 11.4 0.7 1.3 1 1 0 1 1 1 0 NINE Protein PA-IL PF07828.7 KFO95056.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 PA-IL-like protein Ferric_reduct PF01794.14 KFO95058.1 - 3.8e-23 81.9 3.2 3.8e-23 81.9 2.2 1.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Enolase_C PF00113.17 KFO95059.1 - 5e-80 268.6 0.0 5.5e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.1 KFO95059.1 - 1.3e-05 25.0 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KFO95059.1 - 0.00012 21.1 0.4 0.00015 20.8 0.3 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus HSP70 PF00012.15 KFO95060.1 - 3.7e-11 41.6 0.2 6.2e-06 24.4 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein Fez1 PF06818.10 KFO95060.1 - 0.041 13.9 1.1 0.05 13.6 0.8 1.1 1 0 0 1 1 1 0 Fez1 Patched PF02460.13 KFO95061.1 - 4.4e-72 243.2 14.8 6e-72 242.7 10.3 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KFO95061.1 - 6.1e-17 61.4 0.8 6.1e-17 61.4 0.5 3.2 3 1 0 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation DUF3878 PF12994.2 KFO95061.1 - 0.045 12.9 2.0 0.069 12.3 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) DUF2207 PF09972.4 KFO95061.1 - 0.2 10.2 4.2 7.1 5.0 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Tubulin PF00091.20 KFO95062.1 - 6.2e-63 212.4 0.1 7.6e-63 212.2 0.1 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain TRAP-gamma PF07074.7 KFO95064.1 - 2.3e-69 232.2 6.4 2.6e-69 232.1 4.5 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Kei1 PF08552.6 KFO95064.1 - 0.0064 16.1 2.4 0.0084 15.7 1.6 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MatC_N PF07158.6 KFO95064.1 - 0.19 11.5 2.4 0.44 10.3 0.6 1.9 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus SPC25 PF06703.6 KFO95064.1 - 0.24 10.9 3.1 0.15 11.6 1.0 1.6 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ins145_P3_rec PF08709.6 KFO95066.1 - 2e-05 23.7 0.1 2e-05 23.7 0.1 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor I-set PF07679.11 KFO95067.1 - 6.3e-07 29.1 0.0 8.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFO95067.1 - 0.03 14.8 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Peptidase_M10 PF00413.19 KFO95068.1 - 1.5e-60 203.4 0.0 1.9e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 KFO95068.1 - 3.1e-09 36.6 0.0 9e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 KFO95068.1 - 3.8e-06 27.4 0.0 6.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 KFO95068.1 - 9.6e-05 21.8 0.6 0.27 10.6 0.1 2.1 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 KFO95068.1 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFO95068.1 - 0.00042 19.8 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFO95068.1 - 0.0015 18.6 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 KFO95068.1 - 0.005 16.6 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M54 DUF3152 PF11350.3 KFO95068.1 - 0.0057 16.2 0.4 0.046 13.2 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3152) Peptidase_M66 PF10462.4 KFO95068.1 - 0.11 11.3 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin PF01421.14 KFO95068.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M57 PF12388.3 KFO95068.1 - 0.15 11.3 0.3 0.36 10.1 0.2 1.7 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Metallopep PF12044.3 KFO95068.1 - 0.17 10.3 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family ALIX_LYPXL_bnd PF13949.1 KFO95070.1 - 2.4e-30 105.5 13.0 2.9e-30 105.2 9.0 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Snapin_Pallidin PF14712.1 KFO95070.1 - 0.0027 17.9 6.7 0.0045 17.2 1.6 2.2 2 0 0 2 2 2 1 Snapin/Pallidin Sds3 PF08598.6 KFO95070.1 - 0.015 14.8 1.5 0.03 13.8 1.1 1.6 1 1 0 1 1 1 0 Sds3-like Occludin_ELL PF07303.8 KFO95070.1 - 0.02 15.6 4.0 2 9.1 0.5 2.2 2 0 0 2 2 2 0 Occludin homology domain Ly49 PF08391.5 KFO95070.1 - 0.023 14.8 4.9 0.024 14.7 1.7 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region TarH PF02203.10 KFO95070.1 - 0.024 14.4 3.9 0.021 14.6 1.4 1.7 1 1 1 2 2 2 0 Tar ligand binding domain homologue T2SM PF04612.7 KFO95070.1 - 0.059 13.1 3.1 4.9 6.9 0.8 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M GAS PF13851.1 KFO95070.1 - 0.068 12.3 10.1 0.34 10.0 3.9 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TACC PF05010.9 KFO95070.1 - 0.081 12.6 7.1 0.11 12.3 4.9 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF501 PF04417.7 KFO95070.1 - 0.084 12.7 1.1 0.11 12.4 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF501) DUF948 PF06103.6 KFO95070.1 - 0.11 12.3 5.1 0.51 10.2 0.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Rootletin PF15035.1 KFO95070.1 - 0.2 11.6 11.5 0.18 11.7 3.3 2.0 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1843 PF08898.5 KFO95070.1 - 0.24 11.4 3.1 15 5.7 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) Sipho_Gp157 PF05565.6 KFO95070.1 - 0.27 10.7 8.1 3.5 7.1 0.1 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 DUF1978 PF09321.5 KFO95070.1 - 0.28 10.5 10.6 1.2 8.4 7.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) Prefoldin_2 PF01920.15 KFO95070.1 - 0.28 10.9 8.7 3.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit Mnd1 PF03962.10 KFO95070.1 - 0.37 10.4 10.5 3.1 7.4 6.9 2.3 1 1 1 2 2 2 0 Mnd1 family DUF1319 PF07028.6 KFO95070.1 - 0.44 10.7 11.0 1.7 8.8 2.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1319) Syntaxin-6_N PF09177.6 KFO95070.1 - 0.46 10.9 4.0 1.8 9.0 0.9 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1043 PF06295.7 KFO95070.1 - 0.56 9.8 6.6 1.6 8.3 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) BAR PF03114.13 KFO95070.1 - 0.57 9.6 8.7 2.4 7.5 2.3 2.1 1 1 1 2 2 2 0 BAR domain Peptidase_S49_N PF08496.5 KFO95070.1 - 0.65 9.7 4.8 0.63 9.8 2.5 1.6 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Syntaxin_2 PF14523.1 KFO95070.1 - 0.76 9.8 8.0 1.8 8.6 5.0 2.1 1 1 0 1 1 1 0 Syntaxin-like protein Trichoplein PF13868.1 KFO95070.1 - 0.91 7.8 9.9 0.063 11.6 2.6 1.8 2 0 0 2 2 2 0 Tumour suppressor, Mitostatin PP2C_C PF07830.8 KFO95070.1 - 1 9.4 3.6 0.57 10.3 0.4 2.0 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain ADIP PF11559.3 KFO95070.1 - 1.1 9.1 10.5 2.5 8.0 6.8 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlgN PF05130.7 KFO95070.1 - 1.2 9.3 8.5 1.8 8.8 2.1 2.1 1 1 1 2 2 2 0 FlgN protein GrpE PF01025.14 KFO95070.1 - 1.4 8.4 12.3 15 5.0 8.5 2.0 1 1 0 1 1 1 0 GrpE ALMT PF11744.3 KFO95070.1 - 1.4 7.4 5.5 1.5 7.3 3.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Rho_Binding PF08912.6 KFO95070.1 - 1.6 9.1 10.0 2 8.7 3.6 2.3 2 0 0 2 2 2 0 Rho Binding YebO PF13974.1 KFO95070.1 - 1.7 8.5 6.2 0.75 9.6 2.2 1.9 2 0 0 2 2 2 0 YebO-like protein Blo-t-5 PF11642.3 KFO95070.1 - 1.7 8.3 10.3 1.6 8.5 2.9 2.1 1 1 0 2 2 2 0 Mite allergen Blo t 5 Sas10_Utp3 PF04000.10 KFO95070.1 - 2.1 8.6 6.0 2.3 8.4 1.8 2.1 2 0 0 2 2 2 0 Sas10/Utp3/C1D family bZIP_1 PF00170.16 KFO95070.1 - 8.1 6.4 11.8 4.3 7.3 1.2 2.8 3 0 0 3 3 3 0 bZIP transcription factor TSP_C PF05735.7 KFO95071.1 - 2.9e-87 291.4 2.1 3.2e-87 291.3 1.4 1.0 1 0 0 1 1 1 1 Thrombospondin C-terminal region Globin PF00042.17 KFO95073.1 - 4.5e-21 75.2 0.0 6.4e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Globin Trypsin PF00089.21 KFO95074.1 - 4.2e-11 42.8 0.0 4.1e-09 36.3 0.0 2.6 2 1 0 2 2 2 2 Trypsin Trypsin_2 PF13365.1 KFO95074.1 - 4e-06 26.8 0.0 1.2e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 KFO95074.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Hid1 PF12722.2 KFO95076.1 - 0.043 11.5 3.1 0.051 11.2 2.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med21 PF11221.3 KFO95077.1 - 0.22 11.5 7.3 0.056 13.4 2.3 1.8 1 1 1 2 2 2 0 Subunit 21 of Mediator complex RNA_pol_A_bac PF01000.21 KFO95078.1 - 3.7e-30 104.3 0.0 5.7e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain FAST_1 PF06743.10 KFO95079.1 - 2.9e-22 78.1 2.4 2.9e-22 78.1 1.6 4.0 3 1 1 4 4 4 1 FAST kinase-like protein, subdomain 1 FANCI_S2 PF14676.1 KFO95079.1 - 0.062 13.1 5.2 1.1 9.1 0.6 3.5 2 1 1 3 3 3 0 FANCI solenoid 2 HALZ PF02183.13 KFO95080.1 - 0.00017 21.2 1.2 0.00022 20.8 0.8 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper TPD52 PF04201.10 KFO95080.1 - 0.0016 18.1 0.2 0.0017 18.0 0.2 1.0 1 0 0 1 1 1 1 Tumour protein D52 family DASH_Spc19 PF08287.6 KFO95080.1 - 0.0021 17.6 0.0 0.0023 17.5 0.0 1.0 1 0 0 1 1 1 1 Spc19 DivIVA PF05103.8 KFO95080.1 - 0.0068 16.4 0.9 0.0077 16.2 0.6 1.1 1 0 0 1 1 1 1 DivIVA protein bZIP_1 PF00170.16 KFO95080.1 - 0.0073 16.2 0.8 0.0088 15.9 0.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor SYCE1 PF15233.1 KFO95080.1 - 0.016 15.1 0.4 0.017 15.0 0.3 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 GAS PF13851.1 KFO95080.1 - 0.036 13.2 0.4 0.037 13.2 0.3 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.1 KFO95080.1 - 0.039 13.9 0.3 0.044 13.7 0.2 1.0 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 KFO95080.1 - 0.046 13.1 0.8 0.053 13.0 0.5 1.2 1 0 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.3 KFO95080.1 - 0.066 12.9 0.4 0.074 12.7 0.3 1.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Tnp_P_element PF12017.3 KFO95080.1 - 0.069 12.3 0.1 0.076 12.2 0.1 1.0 1 0 0 1 1 1 0 Transposase protein Cep57_CLD_2 PF14197.1 KFO95080.1 - 0.11 12.4 1.1 0.14 12.1 0.8 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.3 KFO95080.1 - 0.11 12.2 2.6 0.13 12.0 1.8 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 KFO95080.1 - 0.12 12.5 0.2 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFP_35_N PF07334.8 KFO95080.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Microtub_assoc PF07989.6 KFO95080.1 - 0.14 12.0 0.9 0.16 11.8 0.6 1.1 1 0 0 1 1 1 0 Microtubule associated IncA PF04156.9 KFO95080.1 - 0.14 11.7 0.6 0.16 11.5 0.4 1.0 1 0 0 1 1 1 0 IncA protein CNPase PF05881.7 KFO95080.1 - 0.15 11.4 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Ifi-6-16 PF06140.8 KFO95081.1 - 3.2e-11 42.8 8.7 3.8e-11 42.6 6.0 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family NAD_binding_11 PF14833.1 KFO95082.1 - 3.3e-09 36.8 1.4 3.3e-09 36.8 1.0 1.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KFO95082.1 - 3.6e-08 33.4 0.3 5.5e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Coiled PF05710.7 KFO95082.1 - 0.047 14.1 0.3 0.054 13.9 0.2 1.3 1 0 0 1 1 1 0 Coiled coil DUF970 PF06153.6 KFO95082.1 - 0.089 12.7 0.0 0.094 12.6 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF970) PHF5 PF03660.9 KFO95083.1 - 2.6e-20 72.4 10.9 2.8e-20 72.3 7.5 1.0 1 0 0 1 1 1 1 PHF5-like protein C1_3 PF07649.7 KFO95083.1 - 0.042 13.8 3.5 0.042 13.8 2.5 3.1 3 0 0 3 3 3 0 C1-like domain PolC_DP2 PF03833.8 KFO95083.1 - 0.36 8.4 4.5 0.37 8.3 3.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 KFO95083.1 - 0.54 9.9 12.2 1.1 9.0 8.5 1.7 1 1 0 1 1 1 0 PHD-finger DZR PF12773.2 KFO95083.1 - 0.73 9.7 10.3 4.6 7.1 7.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.13 KFO95083.1 - 1.7 7.7 9.8 8.6 5.5 0.0 3.8 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others zf-C3HC4_3 PF13920.1 KFO95083.1 - 3.3 7.4 13.3 5.8 6.6 6.0 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) A2L_zn_ribbon PF08792.5 KFO95083.1 - 4.6 6.8 9.5 3.6 7.1 2.5 2.7 2 1 0 2 2 2 0 A2L zinc ribbon domain Prok-RING_1 PF14446.1 KFO95083.1 - 4.8 7.0 15.0 0.87 9.3 1.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF3716 PF12511.3 KFO95083.1 - 5.9 6.5 10.5 2 8.0 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) PDZ PF00595.19 KFO95084.1 - 9.9e-20 70.5 0.2 1.2e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO95084.1 - 1.2e-11 44.3 0.3 1.7e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFO95084.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.5 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Ras PF00071.17 KFO95086.1 - 1.3e-29 102.7 0.0 1.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95086.1 - 0.0076 16.7 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein CENP-M PF11111.3 KFO95086.1 - 0.095 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Arf PF00025.16 KFO95086.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family 7tm_1 PF00001.16 KFO95087.1 - 6.8e-09 35.2 14.8 3.5e-08 32.9 10.3 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 KFO95087.1 - 0.00029 20.1 0.8 0.00029 20.1 0.5 2.5 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc TPR_11 PF13414.1 KFO95088.1 - 5.4e-23 80.4 6.9 1.4e-19 69.4 2.6 2.2 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFO95088.1 - 7.7e-20 69.6 4.2 4.5e-07 29.2 2.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFO95088.1 - 2.3e-17 61.4 4.3 7.7e-07 28.5 1.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFO95088.1 - 3.9e-10 38.7 3.3 0.0001 21.7 1.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFO95088.1 - 4.6e-10 39.8 0.9 8.1e-07 29.5 0.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO95088.1 - 4.3e-09 36.1 5.0 0.00049 19.9 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFO95088.1 - 7.4e-09 35.1 4.3 1e-05 25.3 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFO95088.1 - 6.4e-08 32.5 0.3 0.0067 16.9 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO95088.1 - 2.3e-07 31.0 0.5 0.00057 20.1 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFO95088.1 - 5.1e-06 26.5 2.3 0.11 13.0 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO95088.1 - 0.00012 22.1 4.6 0.00014 21.9 0.8 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFO95088.1 - 0.00013 21.7 0.8 0.043 13.6 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFO95088.1 - 0.0014 18.3 1.1 2.6 8.0 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFO95088.1 - 0.006 16.3 3.6 0.036 13.8 2.6 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFO95088.1 - 0.023 14.6 3.3 4.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KFO95088.1 - 0.027 14.3 2.2 0.031 14.1 0.4 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 KFO95088.1 - 0.034 13.2 1.6 3.3 6.6 0.0 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.4 KFO95088.1 - 0.069 12.5 1.0 0.11 11.9 0.7 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Coatomer_E PF04733.9 KFO95088.1 - 0.091 11.9 0.9 0.34 10.0 0.1 1.8 1 1 0 2 2 2 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.1 KFO95088.1 - 0.24 11.3 4.9 2.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF4398 PF14346.1 KFO95088.1 - 1.9 8.6 5.8 13 5.9 1.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4398) ADH_zinc_N PF00107.21 KFO95090.1 - 1.1e-22 79.9 0.2 1.3e-22 79.7 0.2 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFO95090.1 - 2.6e-15 57.4 0.0 3.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase I-set PF07679.11 KFO95091.1 - 3.9e-12 45.8 0.0 5.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO95091.1 - 4.5e-05 23.4 0.0 7.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO95091.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO95091.1 - 0.0075 16.1 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Pkinase PF00069.20 KFO95092.1 - 2.9e-18 65.9 0.0 3.2e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95092.1 - 7.4e-14 51.4 0.0 8.9e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFO95092.1 - 0.0043 16.8 0.1 0.0057 16.4 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFO95092.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family 7tm_1 PF00001.16 KFO95093.1 - 3.8e-21 75.3 15.8 3.8e-21 75.3 11.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.10 KFO95093.1 - 0.00033 20.4 4.3 0.00033 20.4 3.0 2.7 1 1 1 3 3 3 2 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srv PF10323.4 KFO95093.1 - 0.017 14.2 13.7 0.028 13.5 9.2 1.5 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Prominin PF05478.6 KFO95093.1 - 0.043 11.3 3.5 0.07 10.6 2.5 1.2 1 0 0 1 1 1 0 Prominin BatA PF07584.6 KFO95093.1 - 0.32 11.2 7.9 8.9 6.5 1.3 3.2 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal CopD PF05425.8 KFO95093.1 - 3.6 7.8 9.3 0.63 10.2 1.0 2.9 2 2 1 3 3 3 0 Copper resistance protein D Caprin-1_C PF12287.3 KFO95095.1 - 0.11 11.8 0.8 0.13 11.6 0.5 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term ARA70 PF12489.3 KFO95097.1 - 8.4e-32 109.9 21.2 5.2e-31 107.3 4.1 4.2 3 2 0 3 3 3 2 Nuclear coactivator CTP_transf_2 PF01467.21 KFO95098.1 - 1.6e-12 47.7 0.1 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase SWIB PF02201.13 KFO95098.1 - 0.03 14.0 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 SWIB/MDM2 domain UFD1 PF03152.9 KFO95099.1 - 0.01 15.0 4.7 0.02 14.0 0.7 2.2 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 DUF2745 PF10922.3 KFO95099.1 - 0.014 15.2 2.2 0.21 11.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2745) Lact_bio_phlase PF09508.5 KFO95099.1 - 0.065 10.8 0.3 0.086 10.4 0.2 1.2 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase DUF3347 PF11827.3 KFO95099.1 - 0.072 13.0 20.8 0.36 10.8 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) TMF_TATA_bd PF12325.3 KFO95099.1 - 0.61 9.8 33.3 1.2 8.8 6.9 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 KFO95099.1 - 0.71 10.2 29.4 0.73 10.2 10.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Retrotrans_gag PF03732.12 KFO95099.1 - 2 8.5 16.1 8.2 6.5 1.3 3.9 2 1 0 3 3 3 0 Retrotransposon gag protein HAP1_N PF04849.8 KFO95099.1 - 2.7 6.8 37.8 0.33 9.8 12.2 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region APG6 PF04111.7 KFO95099.1 - 4.4 6.2 36.0 1.8 7.5 12.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 KFO95099.1 - 5.2 6.8 34.2 1.2 8.9 13.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.14 KFO95099.1 - 5.5 6.4 32.3 2.8 7.3 13.3 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1284 PF06935.6 KFO95099.1 - 5.9 7.1 6.8 0.96 9.6 0.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1284) IF-2B PF01008.12 KFO95099.1 - 9 5.1 9.0 0.72 8.7 3.0 1.6 2 0 0 2 2 2 0 Initiation factor 2 subunit family DUF1903 PF08991.5 KFO95100.1 - 1.7e-12 47.2 5.5 1.8e-12 47.2 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) AhpC-TSA PF00578.16 KFO95101.1 - 3.2e-23 81.7 0.0 3.9e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFO95101.1 - 3e-06 26.8 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Yip1 PF04893.12 KFO95102.1 - 8.4e-07 28.6 18.0 8.4e-07 28.6 12.5 1.4 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.4 KFO95102.1 - 0.012 15.8 3.0 0.03 14.5 1.8 2.1 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 MFS_2 PF13347.1 KFO95102.1 - 5.4 5.2 18.6 2.8e+02 -0.4 12.9 2.1 1 1 0 1 1 1 0 MFS/sugar transport protein Prokineticin PF06607.6 KFO95103.1 - 0.0019 18.2 7.2 0.0023 17.9 5.0 1.1 1 0 0 1 1 1 1 Prokineticin PilI PF10623.4 KFO95103.1 - 0.15 12.0 1.8 0.17 11.8 0.5 1.7 1 1 0 1 1 1 0 Plasmid conjugative transfer protein PilI Toxin_21 PF08091.6 KFO95103.1 - 2.5 7.9 12.4 0.062 13.0 3.2 2.2 2 1 0 2 2 2 0 Spider insecticidal peptide CarbpepA_inh PF02977.10 KFO95103.1 - 4.4 6.9 9.9 0.089 12.3 1.9 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor DUF977 PF06163.6 KFO95106.1 - 0.13 11.9 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) DUF766 PF05571.7 KFO95107.1 - 3.5e-96 321.9 13.7 3.9e-96 321.8 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF766) DHC_N1 PF08385.7 KFO95108.1 - 9.1e-27 93.6 2.7 9.7e-27 93.5 1.8 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 G-gamma PF00631.17 KFO95109.1 - 5.8e-11 41.9 0.0 6.3e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 GGL domain EF-hand_7 PF13499.1 KFO95110.1 - 7.1e-14 51.7 2.6 4.1e-06 26.8 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFO95110.1 - 3.5e-13 47.8 1.6 0.00029 19.9 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFO95110.1 - 4.4e-07 29.2 0.1 0.27 11.2 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFO95110.1 - 1.4e-05 24.1 0.8 0.0023 17.2 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFO95110.1 - 0.00038 20.0 2.2 2.2 7.9 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO95110.1 - 0.022 14.7 3.3 0.37 10.8 0.5 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RasGEF_N_2 PF14663.1 KFO95110.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.6 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain XPG_I_2 PF12813.2 KFO95110.1 - 0.065 12.7 0.1 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing PDEase_I PF00233.14 KFO95111.1 - 2e-26 93.1 0.1 2.2e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-DHHC PF01529.15 KFO95112.1 - 2e-28 98.9 10.9 2.5e-28 98.6 7.6 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Pico_P2B PF01552.12 KFO95112.1 - 0.041 14.0 0.1 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Picornavirus 2B protein Baculo_11_kDa PF06143.6 KFO95112.1 - 0.08 12.3 1.2 0.12 11.7 0.8 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family C2 PF00168.25 KFO95113.1 - 5.6e-19 67.7 0.1 7.6e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 C2 domain Myosin_head PF00063.16 KFO95114.1 - 2.1e-48 164.9 0.0 2.7e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFO95114.1 - 7.2e-06 25.1 0.1 2.4e-05 23.5 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif YdjC PF04794.7 KFO95115.1 - 2e-23 83.2 0.0 2.1e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein Propep_M14 PF02244.11 KFO95115.1 - 0.13 11.9 0.5 0.65 9.7 0.4 2.0 1 1 0 1 1 1 0 Carboxypeptidase activation peptide 14-3-3 PF00244.15 KFO95116.1 - 1.4e-43 148.6 0.4 1.5e-43 148.5 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KFO95116.1 - 0.044 13.7 0.0 0.098 12.6 0.0 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 KFO95117.1 - 4.7e-06 26.8 0.1 1.2e-05 25.5 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFO95117.1 - 1.8e-05 24.2 2.9 6.7e-05 22.4 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFO95117.1 - 4.5e-05 23.3 0.4 0.00027 20.9 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KFO95117.1 - 0.00082 19.8 0.4 0.0057 17.1 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO95117.1 - 0.029 14.6 2.5 0.087 13.1 0.9 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) HECT PF00632.20 KFO95118.1 - 7.8e-25 87.6 0.0 9.5e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Metallophos PF00149.23 KFO95119.1 - 0.0014 18.0 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.22 KFO95120.1 - 4.4e-09 36.7 0.0 5.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFO95120.1 - 2.2e-05 24.6 0.0 2.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFO95120.1 - 0.00019 20.9 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KFO95120.1 - 0.0003 21.1 0.0 0.00036 20.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KFO95120.1 - 0.0024 16.6 0.0 0.0028 16.4 0.0 1.0 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Adeno_IVa2 PF02456.10 KFO95120.1 - 0.0026 16.4 0.0 0.0027 16.4 0.0 1.0 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_16 PF13191.1 KFO95120.1 - 0.0026 17.7 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain MutS_V PF00488.16 KFO95120.1 - 0.0049 16.3 0.0 0.0051 16.2 0.0 1.0 1 0 0 1 1 1 1 MutS domain V SMC_N PF02463.14 KFO95120.1 - 0.0069 15.6 0.1 0.0085 15.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFO95120.1 - 0.016 14.2 0.0 0.016 14.2 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KFO95120.1 - 0.017 14.3 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 KFO95120.1 - 0.018 14.2 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Lon_2 PF13337.1 KFO95120.1 - 0.019 13.3 0.0 0.021 13.1 0.0 1.0 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA_14 PF13173.1 KFO95120.1 - 0.037 13.9 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFO95120.1 - 0.037 13.7 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase DUF815 PF05673.8 KFO95120.1 - 0.044 12.7 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KFO95120.1 - 0.05 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KFO95120.1 - 0.067 12.8 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 KFO95120.1 - 0.07 12.5 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 KFO95120.1 - 0.1 11.4 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 KFO95120.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Baculo_helicase PF04735.7 KFO95120.1 - 0.12 9.7 0.0 0.14 9.5 0.0 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase AAA_17 PF13207.1 KFO95120.1 - 0.12 13.1 0.0 0.17 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_transf_29 PF00777.13 KFO95121.1 - 4.6e-07 29.2 0.0 1e-05 24.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) GTP_EFTU PF00009.22 KFO95122.1 - 9.4e-57 191.4 0.0 1.3e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFO95122.1 - 2e-25 88.8 0.0 6.4e-25 87.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFO95122.1 - 1.4e-17 63.5 1.0 1.4e-17 63.5 0.7 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KFO95122.1 - 3e-05 23.5 0.2 8.1e-05 22.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KFO95122.1 - 0.00059 19.7 0.5 0.0018 18.2 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFO95122.1 - 0.019 14.1 0.0 0.045 12.8 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 KFO95122.1 - 0.038 13.8 0.1 7.7 6.3 0.1 2.4 2 0 0 2 2 2 0 Dynamin family PP1_bind PF15276.1 KFO95123.1 - 4.9e-25 87.3 0.7 4.9e-25 87.3 0.5 1.5 2 0 0 2 2 2 1 Protein phosphatase 1 binding SRCR PF00530.13 KFO95125.1 - 2.9e-58 194.3 17.8 7.5e-34 116.0 5.4 2.0 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFO95125.1 - 1.3e-06 28.5 3.9 0.00033 20.8 0.5 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain bZIP_1 PF00170.16 KFO95126.1 - 1.6e-11 43.9 19.6 2.8e-11 43.1 13.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFO95126.1 - 1e-10 41.2 18.9 1.6e-10 40.6 13.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFO95126.1 - 7.6e-08 32.5 7.9 7.6e-08 32.5 5.5 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor SNAPc19 PF15497.1 KFO95126.1 - 0.0022 18.1 1.5 0.0022 18.1 1.0 1.9 2 0 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 AOX PF01786.12 KFO95126.1 - 0.017 14.5 0.2 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Alternative oxidase Seryl_tRNA_N PF02403.17 KFO95126.1 - 0.041 13.9 6.8 0.062 13.3 4.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Vps51 PF08700.6 KFO95126.1 - 0.077 12.8 2.5 0.17 11.7 1.7 1.6 1 0 0 1 1 1 0 Vps51/Vps67 DivIC PF04977.10 KFO95126.1 - 0.083 12.3 6.9 0.19 11.2 4.8 1.6 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 KFO95126.1 - 0.18 10.7 8.9 0.23 10.4 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Macoilin PF09726.4 KFO95126.1 - 0.32 9.2 9.7 0.38 8.9 6.7 1.0 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 KFO95126.1 - 0.34 8.7 3.6 0.38 8.5 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 KFO95126.1 - 1.1 8.9 7.8 1.7 8.3 4.9 1.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ribosomal_L6e PF01159.14 KFO95126.1 - 1.3 9.2 7.3 3 8.1 5.0 1.6 1 1 1 2 2 2 0 Ribosomal protein L6e CDC37_N PF03234.9 KFO95126.1 - 9 6.5 11.8 43 4.3 8.2 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding 7tm_1 PF00001.16 KFO95127.1 - 2.9e-43 147.8 25.6 3.4e-43 147.6 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFO95127.1 - 1.9e-05 23.9 23.5 2.8e-05 23.3 16.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx OTOS PF15182.1 KFO95127.1 - 0.084 12.5 0.0 0.3 10.7 0.0 2.0 1 0 0 1 1 1 0 Otospiralin Git3 PF11710.3 KFO95127.1 - 0.73 9.3 24.7 0.27 10.7 11.2 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 CNH PF00780.17 KFO95128.1 - 3.7e-21 75.7 0.0 4.2e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 CNH domain zf-C2H2 PF00096.21 KFO95129.1 - 2.2e-13 49.6 10.0 1.4e-07 31.4 1.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO95129.1 - 9.5e-11 41.4 1.1 9.5e-11 41.4 0.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO95129.1 - 2.9e-09 36.5 10.0 0.00011 22.2 1.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFO95129.1 - 0.0013 18.8 3.8 0.061 13.5 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc-finger domain DBD_Tnp_Mut PF03108.10 KFO95129.1 - 0.12 11.9 0.5 0.18 11.4 0.4 1.4 1 0 0 1 1 1 0 MuDR family transposase Glyco_hydro_32N PF00251.15 KFO95129.1 - 0.13 11.6 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain zf-C2HC_2 PF13913.1 KFO95129.1 - 0.21 11.3 3.1 0.66 9.7 0.5 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 KFO95129.1 - 0.24 11.6 1.3 0.33 11.2 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFO95129.1 - 1 9.3 6.5 0.24 11.3 2.0 2.0 2 1 0 2 2 2 0 C2H2-type zinc finger DUF456 PF04306.8 KFO95131.1 - 0.099 12.6 4.6 0.049 13.6 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.1 KFO95131.1 - 0.26 10.8 13.2 0.4 10.2 9.2 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 KFO95131.1 - 0.95 9.1 7.1 0.33 10.6 3.2 1.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Chibby PF14645.1 KFO95132.1 - 0.0004 20.2 1.0 0.0004 20.2 0.7 3.1 3 1 0 3 3 3 1 Chibby family DegS PF05384.6 KFO95132.1 - 0.018 14.2 0.2 0.047 12.8 0.1 1.7 1 0 0 1 1 1 0 Sensor protein DegS Stomoxyn PF11585.3 KFO95132.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn TSC22 PF01166.13 KFO95132.1 - 0.57 10.1 5.2 2.6 8.0 0.1 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Med28 PF11594.3 KFO95132.1 - 4.5 7.5 8.1 13 6.0 0.8 2.7 2 1 0 2 2 2 0 Mediator complex subunit 28 7tm_4 PF13853.1 KFO95133.1 - 2.5e-41 140.8 20.6 2.5e-41 140.8 14.3 2.7 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO95133.1 - 4e-33 114.6 29.3 5.2e-33 114.2 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sushi PF00084.15 KFO95134.1 - 2.6e-16 59.6 13.2 5.7e-09 36.2 3.2 2.2 1 1 1 2 2 2 2 Sushi domain (SCR repeat) TACI-CRD2 PF09305.5 KFO95134.1 - 1.6 8.6 6.8 0.19 11.5 1.0 2.2 2 0 0 2 2 2 0 TACI, cysteine-rich domain cEGF PF12662.2 KFO95134.1 - 4.1 7.1 14.4 0.29 10.8 1.0 3.4 2 1 0 2 2 2 0 Complement Clr-like EGF-like Antistasin PF02822.9 KFO95134.1 - 4.3 7.7 12.7 5.5 7.4 0.9 3.9 3 1 0 3 3 3 0 Antistasin family EGF_CA PF07645.10 KFO95134.1 - 7 6.7 14.5 7.9 6.5 0.8 3.1 2 1 0 2 2 2 0 Calcium-binding EGF domain Tme5_EGF_like PF09064.5 KFO95134.1 - 8.9 6.0 6.9 6.5 6.4 0.1 3.3 4 0 0 4 4 4 0 Thrombomodulin like fifth domain, EGF-like TRH PF05438.7 KFO95135.1 - 6.9e-40 136.6 18.9 1.5e-37 129.1 8.5 2.0 1 1 1 2 2 2 2 Thyrotropin-releasing hormone (TRH) Chal_sti_synt_C PF02797.10 KFO95135.1 - 1.6e-05 24.8 0.0 3.5e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain zf-H2C2_2 PF13465.1 KFO95136.1 - 1.5e-27 94.5 85.9 2.2e-07 30.8 3.4 10.2 9 2 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFO95136.1 - 2.9e-18 64.9 78.2 0.0031 17.7 5.9 8.5 9 0 0 9 9 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO95136.1 - 4.1e-10 39.2 68.0 0.0037 17.5 4.2 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFO95136.1 - 7.4e-05 22.7 13.7 0.015 15.5 0.1 9.4 9 3 0 9 9 8 5 C2H2-type zinc-finger domain BolA PF01722.13 KFO95136.1 - 0.0036 17.2 3.4 1.5 8.8 0.2 3.1 3 0 0 3 3 3 2 BolA-like protein zf-C2H2_7 PF15269.1 KFO95136.1 - 0.0048 16.7 2.4 0.0048 16.7 1.7 6.6 3 3 4 7 7 6 3 Zinc-finger C1_3 PF07649.7 KFO95136.1 - 0.025 14.5 31.7 0.27 11.3 0.1 6.8 8 0 0 8 8 8 0 C1-like domain DUF2225 PF09986.4 KFO95136.1 - 0.045 13.1 0.3 0.045 13.1 0.2 3.8 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) RNA_pol_L_2 PF13656.1 KFO95136.1 - 0.054 12.9 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain GAGA PF09237.6 KFO95136.1 - 0.12 12.0 12.6 0.23 11.0 0.2 3.9 4 0 0 4 4 4 0 GAGA factor C1_1 PF00130.17 KFO95136.1 - 0.64 9.7 32.1 1.1 8.9 0.6 5.7 4 2 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.3 KFO95136.1 - 1.5 9.0 0.0 0.66 10.1 1.5 7.7 8 0 0 8 8 7 0 Zinc-finger double-stranded RNA-binding DUF1390 PF07150.6 KFO95136.1 - 7.1 5.9 12.9 0.18 11.1 1.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1390) TFIIIC_delta PF12657.2 KFO95137.1 - 3.7e-14 52.8 0.0 1.8e-13 50.5 0.0 2.1 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term Pkinase_Tyr PF07714.12 KFO95138.1 - 1.4e-37 129.2 0.1 1.7e-37 128.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO95138.1 - 7e-26 90.9 0.0 8.7e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFO95138.1 - 0.00033 20.3 0.1 0.00066 19.4 0.1 1.5 1 0 0 1 1 1 1 SH2 domain DUF3575 PF12099.3 KFO95138.1 - 0.041 12.9 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) CN_hydrolase PF00795.17 KFO95139.1 - 2.2e-10 40.1 0.0 3.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.17 KFO95141.1 - 2.1e-23 81.7 0.0 2.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95141.1 - 4.8e-18 64.9 0.0 6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95141.1 - 1e-13 50.8 0.0 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO95141.1 - 0.0034 17.2 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.3 KFO95141.1 - 0.05 13.3 0.1 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 Calcipressin PF04847.7 KFO95141.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Calcipressin Transthyretin PF00576.16 KFO95142.1 - 4.4e-21 74.8 0.0 4.8e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF290 PF01060.18 KFO95142.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Transthyretin-like family DUF824 PF05688.6 KFO95142.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) DOCK-C2 PF14429.1 KFO95143.1 - 1.3e-31 109.6 0.0 1.5e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Methyltransf_11 PF08241.7 KFO95144.1 - 5.7e-11 42.7 0.0 3.9e-10 40.0 0.0 2.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFO95144.1 - 9e-06 25.4 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 KFO95144.1 - 9.7e-06 24.8 0.0 4.7e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KFO95144.1 - 0.00026 20.6 0.0 0.00043 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain UBN2 PF14223.1 KFO95144.1 - 0.013 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Methyltransf_23 PF13489.1 KFO95144.1 - 0.026 14.2 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFO95144.1 - 0.04 14.3 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KFO95144.1 - 0.14 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Atg8 PF02991.11 KFO95145.1 - 6.1e-41 138.6 0.1 6.7e-41 138.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFO95145.1 - 1.8e-06 28.0 0.0 2.1e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Transglut_core PF01841.14 KFO95146.1 - 2.7e-10 40.4 0.5 5.6e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily MCD PF05292.6 KFO95146.1 - 0.11 11.1 0.0 0.25 9.9 0.0 1.5 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase (MCD) Ras PF00071.17 KFO95147.1 - 1.3e-29 102.6 0.0 1.4e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95147.1 - 4.8e-10 39.9 0.0 6.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein HTH_Mga PF08280.6 KFO95148.1 - 0.0059 16.3 0.1 0.0073 16.0 0.1 1.2 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acatn PF13000.2 KFO95150.1 - 3.4e-09 35.7 0.0 5.1e-09 35.1 0.0 1.3 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 RDD PF06271.7 KFO95150.1 - 0.14 12.0 3.5 0.14 12.0 1.7 1.6 1 1 1 2 2 2 0 RDD family PQ-loop PF04193.9 KFO95151.1 - 1.2e-19 69.5 3.6 2.3e-19 68.6 2.5 1.5 1 0 0 1 1 1 1 PQ loop repeat DUF4500 PF14937.1 KFO95152.1 - 5.3e-38 128.7 0.0 6.1e-38 128.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) LRR_8 PF13855.1 KFO95153.1 - 2.5e-52 174.4 68.6 7.2e-13 48.0 1.7 9.9 5 3 5 10 10 10 9 Leucine rich repeat TIR PF01582.15 KFO95153.1 - 1.3e-28 99.2 0.0 2.5e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 KFO95153.1 - 2.7e-24 84.3 49.4 5.5e-07 29.0 0.6 10.6 4 3 5 11 11 11 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO95153.1 - 9e-14 49.3 45.5 0.74 10.0 0.0 15.4 16 1 1 17 17 17 7 Leucine Rich Repeat LRR_6 PF13516.1 KFO95153.1 - 1.7e-09 36.7 47.9 0.19 11.8 0.6 12.9 13 1 1 14 14 14 7 Leucine Rich repeat TIR_2 PF13676.1 KFO95153.1 - 3e-09 36.9 0.0 9.1e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 TIR domain LRR_7 PF13504.1 KFO95153.1 - 0.00023 20.8 45.7 11 6.7 0.0 13.5 16 0 0 16 16 16 1 Leucine rich repeat LRR_9 PF14580.1 KFO95153.1 - 0.00077 19.0 10.2 0.048 13.2 0.2 3.7 3 1 1 4 4 4 2 Leucine-rich repeat Col_cuticle_N PF01484.12 KFO95153.1 - 2.1 8.1 7.0 2 8.1 3.3 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Mob1_phocein PF03637.12 KFO95155.1 - 3.5e-47 160.3 2.7 4e-47 160.1 1.8 1.0 1 0 0 1 1 1 1 Mob1/phocein family Clathrin PF00637.15 KFO95156.1 - 1.9e-39 134.5 1.7 4e-35 120.5 1.0 2.1 2 0 0 2 2 2 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 KFO95156.1 - 1.2e-05 24.3 0.1 2.1e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Coatomer WD associated region TPR_1 PF00515.23 KFO95156.1 - 0.0015 18.0 0.1 0.014 14.9 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFO95156.1 - 0.0033 17.9 0.1 1.5 9.6 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat ChpXY PF10216.4 KFO95156.1 - 0.0058 15.5 0.0 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 CO2 hydration protein (ChpXY) TPR_2 PF07719.12 KFO95156.1 - 0.011 15.5 0.3 0.29 11.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFO95156.1 - 0.022 14.4 0.3 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.1 KFO95156.1 - 0.081 12.7 0.1 9.1 6.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFO95156.1 - 0.13 12.6 0.5 0.55 10.6 0.1 2.4 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFO95156.1 - 0.16 11.8 0.6 8.7 6.3 0.1 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Mg_trans_NIPA PF05653.9 KFO95157.1 - 4.7e-102 340.9 13.4 5.5e-102 340.7 9.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KFO95157.1 - 2.5e-07 30.7 3.1 2.5e-07 30.7 2.2 3.9 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KFO95157.1 - 1.1e-05 25.5 0.3 1.1e-05 25.5 0.2 3.2 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Myco_arth_vir_N PF09610.5 KFO95157.1 - 0.047 13.6 0.6 0.16 11.9 0.4 1.9 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF1774 PF08611.5 KFO95157.1 - 1.5 9.0 5.3 2 8.6 0.1 3.1 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) Pox_A9 PF04835.7 KFO95157.1 - 7.2 6.6 9.2 4.1 7.3 0.7 3.3 3 0 0 3 3 3 0 A9 protein conserved region OGFr_N PF04664.8 KFO95158.1 - 3.2e-61 206.3 4.7 4.7e-61 205.8 3.3 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region VWD PF00094.20 KFO95159.1 - 9.5e-72 240.3 9.2 2.6e-35 121.9 2.9 2.2 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.6 KFO95159.1 - 5.1e-42 141.9 11.1 3.2e-24 84.9 1.2 5.0 5 0 0 5 5 5 2 C8 domain TIL PF01826.12 KFO95159.1 - 9.8e-23 80.0 39.3 3e-13 49.6 11.0 6.5 6 1 0 6 6 6 2 Trypsin Inhibitor like cysteine rich domain TILa PF12714.2 KFO95159.1 - 2.4e-18 65.6 32.3 2.2e-12 46.5 7.5 4.9 3 1 1 4 4 4 2 TILa domain TAFA PF12020.3 KFO95160.1 - 2e-30 104.7 5.8 2.2e-30 104.6 4.0 1.0 1 0 0 1 1 1 1 TAFA family FXa_inhibition PF14670.1 KFO95160.1 - 2.2 8.4 7.2 1.8 8.7 3.2 2.0 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Lin-8 PF03353.10 KFO95162.1 - 5.4 6.1 11.3 8.7 5.5 7.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sugar_tr PF00083.19 KFO95163.1 - 5e-20 71.5 4.0 6.7e-20 71.0 2.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFO95163.1 - 9e-14 50.9 2.6 1e-13 50.7 1.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3099 PF11298.3 KFO95163.1 - 3.3 7.5 10.2 10 5.9 0.4 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3099) zf-C2H2 PF00096.21 KFO95164.1 - 8.1e-18 63.6 19.8 1.8e-06 27.9 1.5 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO95164.1 - 1.1e-17 63.3 23.8 2.6e-09 36.9 2.0 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO95164.1 - 2.1e-13 49.5 18.2 3.2e-05 23.9 0.9 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KFO95164.1 - 0.0005 20.1 2.4 0.0005 20.1 1.7 2.2 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFO95164.1 - 0.0028 17.7 12.5 0.12 12.4 0.9 3.5 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO95164.1 - 0.012 15.4 18.0 0.22 11.4 0.8 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger RRN7 PF11781.3 KFO95164.1 - 0.02 14.3 3.9 0.37 10.3 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-met PF12874.2 KFO95164.1 - 0.28 11.4 5.8 6.3 7.1 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KFO95164.1 - 0.32 10.7 2.0 9.6 6.0 0.1 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Ogr_Delta PF04606.7 KFO95164.1 - 0.54 9.9 2.8 16 5.2 0.1 3.1 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-BED PF02892.10 KFO95164.1 - 1.3 8.8 15.7 3.9 7.3 1.3 3.2 2 1 1 3 3 3 0 BED zinc finger DUF629 PF04780.7 KFO95164.1 - 2.3 6.6 5.7 0.26 9.7 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Zn_Tnp_IS1595 PF12760.2 KFO95164.1 - 3.5 7.5 8.4 5.5 6.8 0.8 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Peptidase_C14 PF00656.17 KFO95165.1 - 8.6e-51 173.0 0.1 9.8e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Caspase domain 7tm_1 PF00001.16 KFO95166.1 - 2.1e-25 89.3 2.0 2.9e-25 88.8 1.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_P21 PF05313.7 KFO95166.1 - 0.28 10.4 2.9 0.41 9.8 0.3 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein DUF1279 PF06916.8 KFO95167.1 - 1.3e-25 89.4 0.3 2e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Vps4_C PF09336.5 KFO95168.1 - 0.033 14.0 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Dermcidin PF15291.1 KFO95169.1 - 0.17 12.1 3.1 0.25 11.5 1.2 1.9 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide T2SF PF00482.18 KFO95169.1 - 0.21 11.4 3.3 0.28 11.0 1.9 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF976 PF06162.7 KFO95169.1 - 0.27 10.7 2.6 2.5 7.5 0.0 2.4 2 1 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF976) DUF607 PF04678.8 KFO95169.1 - 0.56 10.1 10.5 0.22 11.4 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Peptidase_S46 PF10459.4 KFO95169.1 - 4.7 5.5 12.4 2.4 6.4 6.9 1.6 1 1 0 2 2 2 0 Peptidase S46 Atg14 PF10186.4 KFO95169.1 - 5.7 5.7 22.2 26 3.6 15.3 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 KFO95169.1 - 6.5 6.8 13.3 5.7 7.0 5.0 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF883 PF05957.8 KFO95169.1 - 7.7 6.9 10.1 0.29 11.5 1.8 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) S-AdoMet_synt_M PF02772.11 KFO95170.1 - 5.8e-27 94.0 0.0 9.4e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KFO95170.1 - 2.3e-15 56.6 0.0 3.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PLAT PF01477.18 KFO95171.1 - 7e-15 55.3 0.2 7.4e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain Pkinase PF00069.20 KFO95172.1 - 2e-46 158.2 0.0 2.3e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95172.1 - 3.2e-22 78.8 0.0 4.2e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO95172.1 - 1.2e-08 34.2 0.0 1.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FliT PF05400.8 KFO95172.1 - 0.021 15.1 0.1 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FliT Kdo PF06293.9 KFO95172.1 - 0.024 13.7 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO95172.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFO95172.1 - 0.085 11.6 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KFO95172.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GRASP55_65 PF04495.9 KFO95174.1 - 8.5e-80 265.5 0.1 8.9e-62 207.1 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KFO95174.1 - 9.3e-07 28.6 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 KFO95174.1 - 0.0016 18.1 0.1 0.065 13.0 0.0 2.4 2 1 0 2 2 2 1 Tricorn protease PDZ domain PAZ_siRNAbind PF12212.3 KFO95174.1 - 0.02 14.5 0.3 0.039 13.5 0.2 1.5 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain AMP-binding PF00501.23 KFO95175.1 - 4.6e-11 41.7 0.0 5.6e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme XK-related PF09815.4 KFO95176.1 - 6.7e-72 242.2 23.0 7.5e-72 242.1 15.9 1.0 1 0 0 1 1 1 1 XK-related protein DUF2136 PF09907.4 KFO95176.1 - 0.051 13.6 0.5 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) DUF4571 PF15137.1 KFO95177.1 - 7.4e-86 287.1 5.5 8.2e-86 286.9 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) LON PF02190.11 KFO95178.1 - 3.4e-06 26.8 0.7 5.1e-06 26.3 0.5 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain DUF3786 PF12654.2 KFO95178.1 - 0.025 13.8 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) PIP49_C PF12260.3 KFO95179.1 - 7e-27 94.0 0.2 2e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.1 KFO95179.1 - 9.4e-12 44.8 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 N-term cysteine-rich ER, FAM69 DUF525 PF04379.9 KFO95180.1 - 2.8e-22 78.4 0.1 3.8e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF525) Bromodomain PF00439.20 KFO95182.1 - 3.4e-22 78.1 0.4 7e-22 77.1 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Connexin PF00029.14 KFO95183.1 - 2.1e-49 166.0 0.2 3.2e-49 165.4 0.1 1.2 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFO95183.1 - 3.6e-24 84.3 0.2 9e-24 83.0 0.1 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain CemA PF03040.9 KFO95183.1 - 6.4 6.3 6.4 9.1 5.8 0.0 2.5 3 0 0 3 3 3 0 CemA family Asn_synthase PF00733.16 KFO95184.1 - 1.6e-22 80.2 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFO95184.1 - 5e-07 29.4 0.0 3.9e-06 26.5 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFO95184.1 - 0.0024 17.8 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.15 KFO95184.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family QueC PF06508.8 KFO95184.1 - 0.096 11.9 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC SecY PF00344.15 KFO95185.1 - 5.3e-58 196.6 2.6 6.4e-58 196.3 1.8 1.0 1 0 0 1 1 1 1 SecY translocase YlaH PF14036.1 KFO95185.1 - 0.0025 17.8 0.5 0.23 11.5 0.1 2.6 2 0 0 2 2 2 1 YlaH-like protein DctQ PF04290.7 KFO95185.1 - 0.013 15.2 0.3 0.5 10.1 0.0 2.6 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1430 PF07242.6 KFO95185.1 - 0.64 10.1 4.5 4.2 7.4 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) UQ_con PF00179.21 KFO95186.1 - 3e-39 133.6 0.1 3.3e-39 133.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFO95186.1 - 6.7e-05 22.6 0.0 7.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFO95186.1 - 0.00034 20.4 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFO95186.1 - 0.021 14.5 0.1 0.029 14.0 0.1 1.3 1 1 0 1 1 1 0 UEV domain Med6 PF04934.9 KFO95187.1 - 9.2e-14 51.1 0.1 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component LRR_4 PF12799.2 KFO95188.1 - 2.6e-09 36.4 13.3 7.1e-05 22.3 2.3 3.4 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO95188.1 - 3.4e-07 29.8 13.2 0.00084 19.0 1.3 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KFO95188.1 - 0.0011 18.6 12.2 0.45 10.7 0.3 4.1 3 2 1 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 KFO95188.1 - 0.0077 16.1 11.5 0.69 10.1 0.1 3.9 4 0 0 4 4 4 3 Leucine Rich repeat LRR_7 PF13504.1 KFO95188.1 - 0.014 15.4 12.7 0.85 10.0 0.1 4.7 4 1 1 5 5 5 0 Leucine rich repeat PMM PF03332.8 KFO95189.1 - 1.6e-70 237.0 0.4 1.8e-70 236.9 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase SBP_bac_6 PF13343.1 KFO95189.1 - 0.062 12.6 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Laminin_EGF PF00053.19 KFO95190.1 - 8.4e-15 54.4 31.9 6.4e-09 35.6 8.9 2.3 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) hEGF PF12661.2 KFO95190.1 - 0.0024 17.8 2.8 0.0024 17.8 1.9 4.9 5 0 0 5 5 5 1 Human growth factor-like EGF EGF_2 PF07974.8 KFO95190.1 - 0.047 13.8 3.4 0.047 13.8 2.3 4.6 5 1 0 5 5 5 0 EGF-like domain CENP-Q PF13094.1 KFO95192.1 - 0.029 14.4 0.4 0.029 14.4 0.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit M PF02370.11 KFO95192.1 - 8.2 7.1 6.0 2.1 8.9 1.9 1.8 2 0 0 2 2 2 0 M protein repeat 7tm_4 PF13853.1 KFO95193.1 - 5.2e-40 136.5 13.7 5.2e-40 136.5 9.5 2.1 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO95193.1 - 1.5e-29 102.9 24.4 1.9e-29 102.5 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_A14 PF05767.7 KFO95193.1 - 6.8 6.7 8.5 0.13 12.1 0.5 2.1 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 C4 PF01413.14 KFO95194.1 - 7.5e-73 241.7 5.5 5.7e-49 164.7 0.6 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen MFS_2 PF13347.1 KFO95195.1 - 2.4e-13 49.2 0.8 3.3e-13 48.8 0.6 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 KFO95195.1 - 3.1e-13 49.1 3.0 4.2e-13 48.7 2.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF89 PF01937.14 KFO95196.1 - 9.7e-92 307.4 0.3 1.1e-91 307.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CLTH PF10607.4 KFO95196.1 - 0.044 13.4 1.1 0.51 10.0 0.5 2.1 1 1 1 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain FYVE_2 PF02318.11 KFO95199.1 - 4.1e-24 84.7 22.3 4.4e-24 84.6 15.5 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.7 KFO95199.1 - 0.14 11.6 12.8 0.16 11.5 8.9 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-UDP PF14569.1 KFO95199.1 - 0.76 9.5 13.2 1.1 9.0 9.1 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger LRR_8 PF13855.1 KFO95200.1 - 4.9e-30 103.0 30.4 5.8e-12 45.1 0.6 3.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFO95200.1 - 1.1e-10 40.8 19.5 0.0018 17.8 2.0 3.5 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT PF01462.13 KFO95200.1 - 1.3e-09 37.2 2.7 6e-09 35.1 2.0 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFO95200.1 - 1.5e-08 34.4 0.0 4.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFO95200.1 - 9.1e-08 31.1 24.0 0.0083 16.0 0.5 7.1 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 KFO95200.1 - 8.6e-07 28.1 16.6 0.13 12.5 0.1 6.1 6 0 0 6 6 6 4 Leucine rich repeat LRR_9 PF14580.1 KFO95200.1 - 0.0054 16.2 2.2 0.087 12.3 0.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KFO95200.1 - 1 9.5 16.7 7.3 7.0 0.3 5.3 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase_Tyr PF07714.12 KFO95201.1 - 1.7e-95 318.9 0.0 2e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO95201.1 - 2.3e-47 161.3 0.0 2.8e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFO95201.1 - 6.9e-13 48.8 1.4 1.2e-12 48.0 1.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.9 KFO95201.1 - 0.083 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SprT-like PF10263.4 KFO95202.1 - 2.3e-07 30.5 0.0 1e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 SprT-like family Prp18 PF02840.10 KFO95203.1 - 7.1e-38 129.6 0.1 7.8e-38 129.5 0.0 1.0 1 0 0 1 1 1 1 Prp18 domain Serpin PF00079.15 KFO95204.1 - 2.7e-61 207.7 0.6 3.1e-61 207.5 0.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Ets PF00178.17 KFO95205.1 - 4.4e-25 87.6 0.8 6.9e-25 87.0 0.5 1.3 1 0 0 1 1 1 1 Ets-domain Strabismus PF06638.6 KFO95205.1 - 0.02 13.2 0.1 0.024 12.9 0.1 1.1 1 0 0 1 1 1 0 Strabismus protein DUF4631 PF15450.1 KFO95206.1 - 0.029 12.6 4.7 0.034 12.4 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) DUF972 PF06156.8 KFO95206.1 - 0.047 14.0 3.4 0.061 13.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 KFO95206.1 - 0.084 11.9 5.5 0.091 11.7 3.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 KFO95206.1 - 0.18 11.0 3.4 0.2 10.8 2.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 KFO95206.1 - 0.23 9.8 0.9 0.24 9.7 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 KFO95206.1 - 0.5 10.3 3.5 0.65 10.0 2.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 KFO95206.1 - 0.56 10.5 7.1 0.35 11.1 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) CCDC-167 PF15188.1 KFO95206.1 - 0.72 9.8 7.3 4 7.4 3.7 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Med4 PF10018.4 KFO95206.1 - 0.73 9.1 4.7 0.83 9.0 3.3 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4140 PF13600.1 KFO95206.1 - 0.86 10.0 3.9 1.3 9.4 1.4 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) KicB PF03882.9 KFO95206.1 - 1 7.9 3.9 1.3 7.5 2.4 1.4 1 1 0 1 1 1 0 KicB killing factor IncA PF04156.9 KFO95206.1 - 5.4 6.5 9.8 6.1 6.3 6.8 1.1 1 0 0 1 1 1 0 IncA protein MAD PF05557.8 KFO95207.1 - 0.0091 14.1 10.9 0.012 13.7 7.5 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein TPR_MLP1_2 PF07926.7 KFO95207.1 - 0.0096 15.6 5.6 0.0096 15.6 3.9 1.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein CCDC155 PF14662.1 KFO95207.1 - 0.022 14.3 12.3 0.029 13.9 8.2 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 CALCOCO1 PF07888.6 KFO95207.1 - 0.029 12.6 10.3 0.032 12.5 7.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tail_P2_I PF09684.5 KFO95207.1 - 0.034 13.7 0.2 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) ATG16 PF08614.6 KFO95207.1 - 0.18 11.6 11.6 0.23 11.2 8.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.7 KFO95207.1 - 0.34 10.8 0.1 0.34 10.8 0.0 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat APG6 PF04111.7 KFO95207.1 - 2.7 6.9 10.7 2.9 6.8 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KFO95207.1 - 4 7.5 6.3 60 3.7 4.4 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 KFO95207.1 - 4.7 7.6 10.5 62 3.9 7.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) MRP-S35 PF10246.4 KFO95208.1 - 9.8e-28 96.1 0.0 1e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.18 KFO95208.1 - 0.084 12.9 0.1 0.091 12.8 0.0 1.1 1 0 0 1 1 1 0 S1 RNA binding domain TNFR_c6 PF00020.13 KFO95209.1 - 8.5e-10 38.5 37.7 1.6e-05 24.8 7.0 4.7 3 1 2 5 5 5 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFO95209.1 - 0.00027 20.4 1.6 0.00027 20.4 1.1 4.1 3 2 1 4 4 4 3 GCC2 and GCC3 Catalase PF00199.14 KFO95210.1 - 2.2e-144 480.8 0.1 2.5e-144 480.7 0.0 1.0 1 0 0 1 1 1 1 Catalase LAP1C PF05609.7 KFO95211.1 - 8.1e-95 318.2 0.1 8.9e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Tcp11 PF05794.8 KFO95212.1 - 4.6e-130 434.2 0.0 5.3e-130 434.0 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF1819 PF08849.6 KFO95212.1 - 0.031 13.6 0.2 0.071 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) EF_TS PF00889.14 KFO95212.1 - 0.13 11.6 0.0 0.65 9.2 0.0 2.0 2 0 0 2 2 2 0 Elongation factor TS UDPGT PF00201.13 KFO95213.1 - 1.7e-45 155.5 0.1 1.8e-45 155.4 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 KFO95214.1 - 4.3e-39 134.4 0.0 4.7e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase HlyIII PF03006.15 KFO95215.1 - 6.9e-71 238.1 23.3 8e-71 237.9 16.1 1.0 1 0 0 1 1 1 1 Haemolysin-III related FeoB_C PF07664.7 KFO95215.1 - 1.6 8.2 6.6 5.3 6.5 0.4 3.4 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus MCM PF00493.18 KFO95216.1 - 2.4e-92 309.2 0.1 5.4e-92 308.1 0.0 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KFO95216.1 - 4.2e-26 91.8 0.7 7.6e-26 90.9 0.3 1.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFO95216.1 - 1.9e-08 33.7 0.0 9.2e-06 24.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFO95216.1 - 1.2e-07 31.5 0.0 5.8e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFO95216.1 - 2.3e-05 23.9 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFO95216.1 - 0.004 16.6 0.1 2.2 7.7 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain HypA PF01155.14 KFO95216.1 - 0.0092 15.6 0.1 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family AAA PF00004.24 KFO95216.1 - 0.023 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.8 KFO95216.1 - 0.04 13.5 0.8 0.44 10.2 0.3 2.6 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like NTPase_1 PF03266.10 KFO95216.1 - 0.078 12.6 0.3 2.4 7.8 0.0 2.7 2 1 1 3 3 3 0 NTPase Galactosyl_T PF01762.16 KFO95218.1 - 6.9e-66 221.5 0.0 9.8e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Pkinase PF00069.20 KFO95219.1 - 6.5e-54 182.8 0.1 7.1e-54 182.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95219.1 - 2.1e-26 92.5 0.0 2.7e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO95219.1 - 0.00065 18.8 0.5 0.0012 17.9 0.4 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO95219.1 - 0.0028 17.4 0.1 0.012 15.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFO95219.1 - 0.01 15.1 0.5 0.015 14.6 0.4 1.4 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 KFO95219.1 - 0.014 14.3 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like 7tm_1 PF00001.16 KFO95220.1 - 5e-41 140.5 37.3 3.7e-39 134.4 25.9 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO95220.1 - 1.5e-09 37.4 38.2 3.2e-09 36.3 26.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PH PF00169.24 KFO95221.1 - 4.7e-09 36.4 0.4 6.6e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFO95221.1 - 1.6e-08 34.8 0.1 0.00075 19.7 0.0 2.1 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 KFO95221.1 - 0.00049 19.9 0.2 0.12 12.2 0.0 2.1 1 1 1 2 2 2 2 PH domain Mcp5_PH PF12814.2 KFO95221.1 - 0.0058 16.5 0.3 3 7.7 0.0 2.1 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_8 PF15409.1 KFO95221.1 - 0.0065 16.5 0.0 0.083 12.9 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Serpin PF00079.15 KFO95222.1 - 5.7e-83 279.0 3.3 7.7e-83 278.6 2.3 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pec_lyase_C PF00544.14 KFO95222.1 - 0.0088 15.5 0.2 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Pectate lyase Rad52_Rad22 PF04098.10 KFO95223.1 - 1.3e-53 180.8 0.8 1.8e-53 180.3 0.0 1.6 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 KFO95223.1 - 0.19 9.9 21.1 0.23 9.6 14.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3774 PF12609.3 KFO95223.1 - 6.7 7.6 13.0 0.19 12.5 2.6 2.8 2 1 1 3 3 3 0 Wound-induced protein MyTH4 PF00784.12 KFO95224.1 - 2e-27 95.4 0.2 9.8e-27 93.1 0.0 2.2 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.13 KFO95224.1 - 1.2e-09 38.3 1.3 3.2e-09 37.0 0.5 1.9 2 0 0 2 2 2 1 FERM central domain Pkinase PF00069.20 KFO95225.1 - 2.9e-23 82.3 0.0 1.7e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95225.1 - 1.8e-13 50.1 0.0 8.7e-06 24.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase C6_DPF PF10170.4 KFO95227.1 - 1e-31 108.8 1.5 1.2e-31 108.6 1.1 1.0 1 0 0 1 1 1 1 Cysteine-rich domain C1_3 PF07649.7 KFO95227.1 - 9.8 6.3 7.3 12 5.9 0.5 2.4 2 0 0 2 2 2 0 C1-like domain LRR_8 PF13855.1 KFO95228.1 - 9.9e-66 217.3 42.2 8e-16 57.5 2.4 7.2 5 1 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFO95228.1 - 6.5e-45 150.0 53.4 3.5e-08 32.8 1.8 10.2 3 2 10 13 13 13 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO95228.1 - 2.3e-38 124.2 32.3 0.0021 17.8 0.3 15.8 15 2 2 17 17 17 10 Leucine Rich Repeat LRR_5 PF13306.1 KFO95228.1 - 1.2e-24 86.4 12.2 7.9e-07 28.8 0.0 4.7 1 1 6 7 7 7 7 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO95228.1 - 5.3e-21 71.0 35.1 0.15 12.3 0.1 14.0 15 0 0 15 15 15 7 Leucine rich repeat LRR_6 PF13516.1 KFO95228.1 - 5.5e-15 53.7 48.8 0.23 11.6 0.4 13.7 16 0 0 16 16 16 8 Leucine Rich repeat LRR_9 PF14580.1 KFO95228.1 - 7.4e-10 38.6 10.2 0.027 14.0 0.0 5.2 1 1 4 5 5 5 5 Leucine-rich repeat LRRNT PF01462.13 KFO95228.1 - 0.81 9.2 4.3 20 4.8 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain TPR_7 PF13176.1 KFO95229.1 - 0.087 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 KFO95230.1 - 1.6e-14 53.4 4.7 1.8e-14 53.3 3.2 1.0 1 0 0 1 1 1 1 E1-E2 ATPase YuiB PF14068.1 KFO95230.1 - 0.044 14.1 4.0 0.065 13.5 2.8 1.3 1 0 0 1 1 1 0 Putative membrane protein TipAS PF07739.8 KFO95231.1 - 0.029 14.6 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain 7tm_4 PF13853.1 KFO95232.1 - 2e-12 47.1 2.7 2.3e-12 46.9 1.9 1.1 1 0 0 1 1 1 1 Olfactory receptor RRM_5 PF13893.1 KFO95233.1 - 6.6e-40 134.7 5.6 2.5e-15 56.0 0.3 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95233.1 - 1.2e-22 79.6 0.8 6.3e-12 45.3 0.1 4.3 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO95233.1 - 9.9e-17 60.3 0.2 4.1e-05 23.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFO95233.1 - 0.0057 16.3 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 Limkain b1 DUF4523 PF15023.1 KFO95233.1 - 0.0082 15.6 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Ion_trans PF00520.26 KFO95234.1 - 2.4e-31 108.5 9.5 2.8e-31 108.3 5.8 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFO95234.1 - 2.9e-09 36.5 6.2 2.9e-09 36.5 4.3 2.6 2 0 0 2 2 2 1 Ion channel Sigma_reg_N PF13800.1 KFO95234.1 - 0.0041 17.1 0.3 0.35 10.9 0.0 2.6 2 0 0 2 2 2 1 Sigma factor regulator N-terminal BTB_2 PF02214.17 KFO95234.1 - 0.07 13.3 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain PKD_channel PF08016.7 KFO95234.1 - 0.14 10.5 6.1 0.44 8.9 2.3 2.2 1 1 1 2 2 2 0 Polycystin cation channel DUF202 PF02656.10 KFO95234.1 - 1.6 9.0 8.3 18 5.6 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF1325 PF07039.6 KFO95236.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Cadherin PF00028.12 KFO95237.1 - 1.8e-16 60.1 0.0 2.1e-13 50.3 0.0 2.3 2 1 0 2 2 2 2 Cadherin domain Cadherin PF00028.12 KFO95238.1 - 3.4e-17 62.4 0.0 2.6e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Cadherin domain VCBS PF13517.1 KFO95239.1 - 0.13 12.6 0.3 0.15 12.4 0.2 1.3 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DS PF01916.12 KFO95240.1 - 9.6e-24 84.0 0.0 1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Ion_trans PF00520.26 KFO95241.1 - 1.6e-05 24.2 0.6 1.7e-05 24.1 0.4 1.0 1 0 0 1 1 1 1 Ion transport protein DUF423 PF04241.10 KFO95241.1 - 0.0038 17.1 0.5 0.0043 16.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) PKD_channel PF08016.7 KFO95241.1 - 0.11 10.9 0.5 0.11 10.9 0.4 1.0 1 0 0 1 1 1 0 Polycystin cation channel Ras PF00071.17 KFO95242.1 - 9.9e-57 190.8 0.0 1.1e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95242.1 - 8.9e-16 58.4 0.0 1.4e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO95242.1 - 3.6e-10 39.3 0.0 5.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFO95242.1 - 0.0027 16.8 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFO95242.1 - 0.083 12.8 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Frag1 PF10277.4 KFO95243.1 - 7.2e-12 45.2 7.9 7.9e-12 45.1 5.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2157 PF09925.4 KFO95243.1 - 0.018 14.6 1.9 0.019 14.5 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Neur_chan_memb PF02932.11 KFO95244.1 - 3.6e-39 135.0 1.7 2.6e-37 128.9 1.2 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFO95244.1 - 4.2e-39 133.9 0.0 1e-31 109.7 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain WD40 PF00400.27 KFO95245.1 - 4.5e-07 29.5 0.6 0.067 13.1 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Arrestin_N PF00339.24 KFO95246.1 - 9.1e-39 132.6 0.0 7.7e-33 113.4 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFO95246.1 - 1.4e-22 80.2 0.4 4.9e-22 78.4 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF2393 PF09624.5 KFO95246.1 - 0.0072 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2393) LDB19 PF13002.2 KFO95246.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Spo0M PF07070.6 KFO95246.1 - 0.045 13.1 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 SpoOM protein BatD PF13584.1 KFO95246.1 - 0.07 11.7 0.0 0.094 11.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance AP3B1_C PF14796.1 KFO95246.1 - 0.1 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal CBM49 PF09478.5 KFO95246.1 - 0.14 12.2 0.2 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Pro_isomerase PF00160.16 KFO95248.1 - 9.9e-50 168.7 0.5 1.1e-49 168.6 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PX PF00787.19 KFO95249.1 - 2e-13 50.0 0.2 2.5e-13 49.8 0.2 1.1 1 0 0 1 1 1 1 PX domain FANCI_HD1 PF14679.1 KFO95249.1 - 0.087 12.5 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 FANCI helical domain 1 Vps5 PF09325.5 KFO95250.1 - 1.8e-83 279.4 21.0 1.8e-83 279.4 14.6 1.6 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 KFO95250.1 - 6.2e-28 96.8 0.7 2.8e-27 94.7 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 KFO95250.1 - 0.00011 21.5 2.3 0.0062 15.8 1.6 2.4 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein HR1 PF02185.11 KFO95250.1 - 0.027 14.1 4.1 0.5 10.1 0.5 3.0 2 0 0 2 2 2 0 Hr1 repeat DivIC PF04977.10 KFO95250.1 - 0.088 12.3 2.7 3.6 7.1 0.1 3.0 2 0 0 2 2 2 0 Septum formation initiator FUSC PF04632.7 KFO95250.1 - 0.22 9.8 3.6 0.33 9.3 2.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2833 PF11090.3 KFO95250.1 - 0.42 10.7 2.3 0.46 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) Arfaptin PF06456.8 KFO95250.1 - 0.81 8.9 11.8 0.034 13.4 2.4 2.4 2 1 0 2 2 2 0 Arfaptin-like domain Lipase_chap PF03280.9 KFO95250.1 - 0.97 8.9 15.9 0.14 11.6 6.7 2.7 2 1 2 4 4 4 0 Proteobacterial lipase chaperone protein YgaB PF14182.1 KFO95250.1 - 3.6 7.8 14.4 0.097 12.9 1.4 3.7 3 1 1 5 5 5 0 YgaB-like protein PAT1 PF09770.4 KFO95251.1 - 4.5e-34 117.8 21.9 3.2e-19 68.7 2.8 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 KFO95252.1 - 9.4e-09 35.4 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Ribosomal_S17e PF00833.13 KFO95253.1 - 7.8e-54 180.6 0.1 8.8e-54 180.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 RRM_1 PF00076.17 KFO95254.1 - 3.3e-09 36.2 0.0 0.0057 16.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95254.1 - 2.3e-07 30.7 0.0 7.8e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.19 KFO95254.1 - 0.47 10.3 7.6 0.96 9.4 5.3 1.4 1 0 0 1 1 1 0 B-box zinc finger Adaptin_N PF01602.15 KFO95255.1 - 2.3e-177 590.4 21.5 2.8e-177 590.2 14.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.1 KFO95255.1 - 3.6e-52 175.9 0.0 7.5e-52 174.8 0.0 1.6 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.2 KFO95255.1 - 2e-10 40.8 5.5 4.5e-05 23.3 0.2 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFO95255.1 - 4.4e-10 39.7 9.5 9.8e-07 28.9 0.3 4.7 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.17 KFO95255.1 - 3.2e-07 29.8 1.5 0.98 9.6 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KFO95255.1 - 0.00049 20.4 2.7 15 6.2 0.0 5.5 5 1 1 6 6 6 1 HEAT-like repeat GRIP PF01465.15 KFO95255.1 - 0.048 13.1 0.5 1.9 8.0 0.1 2.7 2 0 0 2 2 2 0 GRIP domain Daxx PF03344.10 KFO95255.1 - 2.8 6.3 24.7 4.7 5.5 17.1 1.3 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 KFO95255.1 - 6.5 4.9 29.7 11 4.1 20.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LRAT PF04970.8 KFO95256.1 - 0.0023 17.8 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 KFO95256.1 - 0.0032 17.2 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family Hormone_recep PF00104.25 KFO95257.1 - 2.2e-28 98.7 0.0 6.8e-28 97.1 0.0 1.7 2 1 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO95257.1 - 3.5e-28 97.6 14.1 4e-28 97.4 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Myosin_head PF00063.16 KFO95258.1 - 7.9e-207 688.5 6.5 2.1e-178 594.5 2.1 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) RhoGAP PF00620.22 KFO95258.1 - 9.8e-48 161.6 0.4 1.3e-46 158.0 0.0 2.9 3 0 0 3 3 3 1 RhoGAP domain RA PF00788.18 KFO95258.1 - 2e-21 76.2 0.1 1.1e-20 73.8 0.0 2.5 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain IQ PF00612.22 KFO95258.1 - 3.9e-15 53.9 43.5 0.00094 18.6 0.2 7.1 6 1 1 7 7 7 5 IQ calmodulin-binding motif C1_1 PF00130.17 KFO95258.1 - 1.9e-05 24.2 12.3 3.6e-05 23.4 8.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.1 KFO95258.1 - 0.0012 19.0 0.2 0.099 12.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain HemX PF04375.9 KFO95258.1 - 0.27 9.7 16.6 0.17 10.4 7.2 2.2 2 0 0 2 2 2 0 HemX Peptidase_C48 PF02902.14 KFO95259.1 - 1.7e-13 50.7 0.6 4.4e-13 49.3 0.4 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GRAM PF02893.15 KFO95260.1 - 3.2e-16 58.5 0.1 8.5e-16 57.2 0.0 1.8 1 0 0 1 1 1 1 GRAM domain PK PF00224.16 KFO95261.1 - 6.7e-168 557.7 4.5 8.1e-168 557.4 3.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KFO95261.1 - 7.8e-30 102.8 0.0 2.3e-29 101.3 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KFO95261.1 - 0.00026 19.9 0.5 0.00059 18.7 0.4 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PARP PF00644.15 KFO95262.1 - 5.1e-13 48.9 0.2 1e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RRM_1 PF00076.17 KFO95263.1 - 5.8e-37 125.1 0.0 6.8e-18 64.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95263.1 - 1.8e-26 91.8 0.0 2.2e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95263.1 - 3.3e-21 74.8 0.1 3.7e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFO95263.1 - 0.01 15.8 0.0 0.75 9.8 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain RRM_3 PF08777.6 KFO95263.1 - 0.059 13.2 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.17 KFO95264.1 - 7.2e-16 57.5 0.0 1.3e-15 56.7 0.0 1.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95264.1 - 3.5e-08 33.3 0.0 5.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95264.1 - 0.00012 21.8 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_20 PF00728.17 KFO95265.1 - 4.8e-83 279.2 0.0 5.9e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain IBR PF01485.16 KFO95266.1 - 2.2e-14 53.0 9.9 2.2e-14 53.0 6.9 4.2 3 1 1 4 4 4 1 IBR domain zf-C3HC4_2 PF13923.1 KFO95266.1 - 1.6e-06 28.0 6.4 1.6e-06 28.0 4.5 3.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO95266.1 - 1.3e-05 24.9 4.2 1.3e-05 24.9 2.9 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFO95266.1 - 0.00027 20.7 21.8 0.0025 17.6 3.6 3.7 4 0 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFO95266.1 - 0.00032 20.2 3.8 0.00032 20.2 2.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO95266.1 - 0.00072 19.2 5.9 0.00072 19.2 4.1 3.4 3 0 0 3 3 3 1 zinc-RING finger domain DUF3287 PF11690.3 KFO95266.1 - 0.072 13.1 3.3 0.75 9.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) POTRA_2 PF08479.6 KFO95266.1 - 0.14 11.8 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type zf-RING_UBOX PF13445.1 KFO95266.1 - 2.9 7.6 16.6 0.13 12.0 0.9 3.8 3 1 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.1 KFO95266.1 - 5.8 6.5 24.7 0.67 9.5 3.4 4.0 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain ISK_Channel PF02060.10 KFO95267.1 - 9.7e-10 38.1 0.1 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Slow voltage-gated potassium channel AMP-binding PF00501.23 KFO95268.1 - 6.9e-92 307.9 0.0 8.8e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO95268.1 - 0.00085 20.2 0.0 0.0024 18.8 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAGAT PF03982.8 KFO95269.1 - 1.6e-119 397.9 0.1 2.1e-119 397.6 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase B3_4 PF03483.12 KFO95270.1 - 2.4e-28 98.7 0.1 4.3e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFO95270.1 - 2.2e-17 62.6 0.0 2.9e-16 59.0 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetase B5 domain PAP2 PF01569.16 KFO95271.1 - 7.3e-19 67.7 2.7 7.3e-19 67.7 1.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KFO95271.1 - 0.0008 18.9 1.8 0.0022 17.5 1.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily Flavi_NS4A PF01350.12 KFO95271.1 - 0.48 9.9 4.0 6 6.4 0.1 2.4 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A PAP2_C PF14360.1 KFO95271.1 - 7.6 6.8 9.3 0.38 11.0 0.9 2.7 3 0 0 3 3 3 0 PAP2 superfamily C-terminal PAX PF00292.13 KFO95272.1 - 2.6e-32 111.1 1.1 1.5e-22 79.6 0.0 2.3 2 0 0 2 2 2 2 'Paired box' domain Pax7 PF12360.3 KFO95272.1 - 9.8e-24 83.3 7.8 2.5e-23 82.0 5.4 1.7 1 0 0 1 1 1 1 Paired box protein 7 Homeobox PF00046.24 KFO95272.1 - 5.5e-23 80.3 6.7 9.4e-23 79.5 4.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO95272.1 - 0.00024 20.7 0.4 0.00064 19.3 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain QLQ PF08880.6 KFO95272.1 - 0.22 10.9 1.7 3.9 6.9 0.1 3.2 4 0 0 4 4 4 0 QLQ Ephrin_lbd PF01404.14 KFO95273.1 - 1.3e-77 259.5 0.0 2.5e-77 258.6 0.0 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase_Tyr PF07714.12 KFO95273.1 - 4.4e-55 186.5 0.8 4.8e-36 124.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase fn3 PF00041.16 KFO95273.1 - 7e-34 115.8 2.1 6e-17 61.5 0.1 3.0 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.1 KFO95273.1 - 9.1e-26 90.0 0.2 1.8e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_2 PF07647.12 KFO95273.1 - 6.9e-21 73.8 0.0 1.3e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase PF00069.20 KFO95273.1 - 3.7e-20 72.1 0.5 2.9e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain SAM_1 PF00536.25 KFO95273.1 - 1.1e-19 70.3 0.0 1.9e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 KFO95273.1 - 3.7e-06 26.4 5.0 3.7e-06 26.4 3.4 2.9 2 2 1 3 3 3 1 GCC2 and GCC3 SusE PF14292.1 KFO95273.1 - 0.00087 19.0 0.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 SusE outer membrane protein Interfer-bind PF09294.5 KFO95273.1 - 0.0036 17.2 0.5 0.73 9.8 0.0 3.5 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III CD34_antigen PF06365.7 KFO95273.1 - 0.027 14.1 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 CD34/Podocalyxin family Tissue_fac PF01108.12 KFO95273.1 - 0.05 13.3 0.3 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 Tissue factor TMEM154 PF15102.1 KFO95273.1 - 0.09 12.4 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 1 0 TMEM154 protein family AMP-binding PF00501.23 KFO95274.1 - 3.1e-73 246.5 0.0 4.6e-73 245.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO95274.1 - 0.0001 23.1 0.0 0.00018 22.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RIO1 PF01163.17 KFO95275.1 - 2.4e-53 180.2 2.1 2.4e-53 180.2 1.5 1.9 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 KFO95275.1 - 4.9e-25 87.4 0.9 9.6e-25 86.4 0.1 2.0 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 KFO95275.1 - 1.2e-09 38.2 2.6 8.6e-05 22.3 0.3 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFO95275.1 - 3.7e-08 32.6 1.3 7.2e-07 28.4 0.9 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KFO95275.1 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PIP49_C PF12260.3 KFO95275.1 - 0.026 13.9 0.1 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase PF00069.20 KFO95275.1 - 0.033 13.3 0.2 0.083 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein kinase domain SNF2_N PF00176.18 KFO95276.1 - 1.2e-74 250.8 1.0 2.6e-74 249.7 0.7 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 KFO95276.1 - 8.7e-33 112.5 0.8 8.7e-33 112.5 0.5 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 KFO95276.1 - 1.7e-27 94.8 10.0 5.3e-16 58.0 0.0 4.3 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFO95276.1 - 6.3e-14 51.6 0.0 1.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_transf_29 PF00777.13 KFO95277.1 - 1.1e-76 257.4 0.0 1.3e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) OATP PF03137.15 KFO95278.1 - 1.5e-30 105.8 0.7 1.9e-30 105.4 0.5 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFO95278.1 - 0.2 10.3 6.2 0.31 9.7 4.3 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily FixP_N PF14715.1 KFO95278.1 - 9.8 5.6 6.5 13 5.3 1.1 2.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Cu2_monoox_C PF03712.10 KFO95279.1 - 3.5e-49 166.1 0.3 6.5e-49 165.2 0.2 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.15 KFO95279.1 - 2.1e-31 108.6 0.0 4.5e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.16 KFO95279.1 - 2.1e-27 93.6 6.3 1.4e-06 27.9 0.1 5.8 5 0 0 5 5 5 4 NHL repeat BatD PF13584.1 KFO95279.1 - 0.015 13.9 0.1 0.022 13.3 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF912 PF06024.7 KFO95279.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) rve PF00665.21 KFO95280.1 - 3.3e-10 40.1 0.0 1.9e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 KFO95280.1 - 4.4e-05 22.7 1.9 0.00014 21.2 1.3 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Pox_A3L PF05288.6 KFO95280.1 - 0.078 12.7 0.3 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Poxvirus A3L Protein His_Phos_2 PF00328.17 KFO95281.1 - 1.3e-109 366.6 1.3 1.8e-109 366.2 0.9 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KFO95281.1 - 0.00013 21.4 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 KFO95281.1 - 0.018 15.1 0.1 0.082 12.9 0.0 2.2 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) UNC119_bdg PF15435.1 KFO95282.1 - 1.2e-104 347.8 0.4 1.3e-104 347.7 0.3 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue PH PF00169.24 KFO95283.1 - 8.2e-26 90.2 0.1 3.6e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 PH domain PDZ PF00595.19 KFO95283.1 - 1.1e-13 51.1 0.0 2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH_11 PF15413.1 KFO95283.1 - 2.5e-11 43.8 9.2 1.8e-06 28.1 2.3 4.3 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 KFO95283.1 - 4.3e-08 33.1 0.8 2.6e-06 27.3 0.4 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.1 KFO95283.1 - 6.2e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.1 KFO95283.1 - 0.0019 18.3 0.5 2.8 8.1 0.0 3.5 2 2 1 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 KFO95283.1 - 0.019 14.8 0.1 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 PH domain TcdB_N PF12918.2 KFO95283.1 - 0.15 12.1 0.5 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain NUDIX PF00293.23 KFO95284.1 - 6.5e-16 58.2 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.2 KFO95284.1 - 2e-12 47.2 0.1 4.1e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFO95284.1 - 9.1e-11 41.0 0.7 1.2e-07 31.1 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KFO95284.1 - 7.4e-10 38.7 0.0 1.8e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO95284.1 - 9.1e-10 38.7 2.1 5.6e-07 29.9 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO95284.1 - 2.1e-08 33.6 1.0 7.3e-06 25.7 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat NUDIX-like PF09296.6 KFO95284.1 - 1.7e-06 28.2 0.0 3.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KFO95284.1 - 2.4e-06 26.9 4.0 4.3e-06 26.1 2.8 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Yae1_N PF09811.4 KFO95285.1 - 1.9e-20 72.0 63.6 1.5e+04 -24.2 44.1 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Tubulin PF00091.20 KFO95286.1 - 3.4e-06 27.0 0.0 3.5e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin PF00091.20 KFO95288.1 - 9.3e-55 185.7 0.2 1.9e-48 165.1 0.0 2.1 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFO95288.1 - 1.1e-51 174.1 0.0 2.4e-51 172.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFO95288.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF4253 PF14062.1 KFO95288.1 - 0.05 13.2 0.0 1.3 8.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) DnaJ PF00226.26 KFO95290.1 - 4.8e-28 96.6 4.8 7.5e-28 96.0 3.3 1.3 1 0 0 1 1 1 1 DnaJ domain UIM PF02809.15 KFO95290.1 - 0.00059 19.1 4.6 0.00059 19.1 3.2 2.0 2 0 0 2 2 2 1 Ubiquitin interaction motif Y_phosphatase PF00102.22 KFO95291.1 - 6.7e-74 248.1 0.0 8.7e-74 247.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFO95291.1 - 0.0075 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFO95291.1 - 0.041 13.9 0.1 0.51 10.3 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFO95291.1 - 0.048 13.9 0.1 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family Peptidase_M18 PF02127.10 KFO95292.1 - 6.2e-163 542.3 0.0 6.9e-163 542.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KFO95292.1 - 6.3e-08 31.7 0.0 5.4e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Filament PF00038.16 KFO95293.1 - 1.7e-116 389.0 45.4 2e-116 388.8 31.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.9 KFO95293.1 - 1e-23 83.8 12.6 4.6e-23 81.7 7.9 2.3 2 0 0 2 2 2 1 Intermediate filament head (DNA binding) region Reo_sigmaC PF04582.7 KFO95293.1 - 0.0001 21.5 3.1 0.42 9.7 0.1 3.2 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KFO95293.1 - 0.002 15.9 44.1 0.0097 13.6 30.4 2.5 1 1 0 1 1 1 1 Myosin tail HR1 PF02185.11 KFO95293.1 - 0.0037 16.9 12.4 0.0037 16.9 8.6 5.4 4 2 1 5 5 5 2 Hr1 repeat WEMBL PF05701.6 KFO95293.1 - 0.0077 14.7 31.4 0.11 10.9 8.7 2.3 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.7 KFO95293.1 - 0.048 13.4 13.7 1.5 8.6 0.3 3.9 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HAUS5 PF14817.1 KFO95293.1 - 0.051 12.1 25.2 0.075 11.5 17.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF1664 PF07889.7 KFO95293.1 - 0.15 11.8 16.4 0.029 14.1 1.3 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3510 PF12022.3 KFO95293.1 - 0.25 11.4 7.3 1.9 8.5 0.3 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF3510) CENP-H PF05837.7 KFO95293.1 - 0.27 11.4 29.4 0.19 11.9 1.0 4.7 2 2 3 5 5 5 0 Centromere protein H (CENP-H) Tropomyosin_1 PF12718.2 KFO95293.1 - 0.36 10.6 39.8 1.6 8.5 5.2 4.1 1 1 4 5 5 5 0 Tropomyosin like DUF948 PF06103.6 KFO95293.1 - 0.47 10.3 9.6 1.1 9.1 0.3 4.0 3 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) MxiH PF09392.5 KFO95293.1 - 0.59 10.7 3.8 2.4 8.8 1.1 3.0 1 1 1 2 2 2 0 Type III secretion needle MxiH like DUF4140 PF13600.1 KFO95293.1 - 0.86 10.0 32.0 0.7 10.3 2.1 5.7 1 1 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.6 KFO95293.1 - 1.3 7.5 29.9 0.34 9.5 2.9 2.6 1 1 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 KFO95293.1 - 1.4 7.2 28.3 0.21 9.9 15.0 2.2 1 1 1 2 2 2 0 AAA domain DUF4515 PF14988.1 KFO95293.1 - 1.9 8.0 39.3 0.097 12.3 5.4 3.1 1 1 2 3 3 2 0 Domain of unknown function (DUF4515) TPR_MLP1_2 PF07926.7 KFO95293.1 - 2.1 8.1 39.6 6.7 6.4 0.8 4.6 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 KFO95293.1 - 2.9 7.9 16.3 8.8 6.4 0.0 4.0 2 2 1 3 3 3 0 Proteins of 100 residues with WXG WD40_alt PF14077.1 KFO95293.1 - 3.6 7.2 11.4 23 4.7 1.1 4.6 4 1 0 4 4 3 0 Alternative WD40 repeat motif IncA PF04156.9 KFO95293.1 - 5.3 6.5 44.7 1.4 8.4 5.2 3.7 1 1 3 4 4 4 0 IncA protein ERM PF00769.14 KFO95293.1 - 5.5 6.4 43.7 2.9 7.3 12.4 3.2 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DUF4200 PF13863.1 KFO95293.1 - 5.9 6.8 43.7 0.11 12.4 3.8 4.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4200) HGTP_anticodon PF03129.15 KFO95293.1 - 9.5 6.2 9.6 0.74 9.7 0.1 3.5 4 0 0 4 4 4 0 Anticodon binding domain I-set PF07679.11 KFO95294.1 - 4.4e-20 71.3 0.0 5.1e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 KFO95294.1 - 4e-08 33.1 0.0 1.1e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFO95294.1 - 3.5e-07 30.2 0.0 4.4e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO95294.1 - 3.4e-05 23.8 0.0 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO95294.1 - 0.0053 17.2 0.0 0.026 15.0 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin domain BiPBP_C PF06832.7 KFO95294.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family NTP_transferase PF00483.18 KFO95295.1 - 1.8e-12 47.1 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KFO95295.1 - 9.2e-08 31.2 10.6 8.8e-07 28.1 0.7 4.3 2 1 2 4 4 4 1 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 KFO95295.1 - 0.0026 16.3 0.3 0.039 12.5 0.1 2.0 2 0 0 2 2 2 1 L-fucokinase Hexapep_2 PF14602.1 KFO95295.1 - 0.39 10.3 4.3 0.16 11.5 0.3 2.5 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase RhoGAP PF00620.22 KFO95296.1 - 1.6e-37 128.4 0.0 2e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 KFO95296.1 - 1.4e-06 27.9 4.8 3.3e-06 26.7 3.3 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFO95296.1 - 0.007 16.0 4.7 0.018 14.7 3.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.24 KFO95296.1 - 0.11 12.2 4.8 0.23 11.1 3.3 1.6 1 0 0 1 1 1 0 PHD-finger MCM2_N PF12619.3 KFO95297.1 - 0.12 12.3 1.5 0.11 12.4 1.1 1.3 1 1 0 1 1 1 0 Mini-chromosome maintenance protein 2 ASC PF00858.19 KFO95298.1 - 1e-156 522.0 0.0 1.2e-156 521.8 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF4203 PF13886.1 KFO95299.1 - 6.3e-58 195.7 35.7 7.5e-58 195.4 24.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2755 PF10954.3 KFO95299.1 - 1.6 8.5 10.0 0.42 10.3 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2755) IBV_3C PF03620.8 KFO95299.1 - 2.5 8.0 6.9 0.27 11.1 0.9 2.3 3 0 0 3 3 3 0 IBV 3C protein I-set PF07679.11 KFO95300.1 - 1.1e-179 582.8 0.0 1.6e-19 69.5 0.0 18.0 18 0 0 18 18 18 17 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO95300.1 - 6.3e-98 321.0 1.1 3.3e-09 36.7 0.0 15.5 14 2 2 16 16 16 14 Immunoglobulin domain ig PF00047.20 KFO95300.1 - 4.6e-58 193.2 4.8 8e-05 22.6 0.0 16.6 17 1 0 17 17 17 13 Immunoglobulin domain V-set PF07686.12 KFO95300.1 - 8.4e-57 190.0 10.6 3.2e-06 26.9 0.0 20.5 13 6 4 17 17 17 12 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO95300.1 - 2.3e-26 92.0 0.2 7.8e-05 23.1 0.0 14.6 14 1 0 14 14 14 3 Immunoglobulin domain C1-set PF07654.10 KFO95300.1 - 1e-14 54.3 4.5 0.43 10.6 0.0 11.7 12 0 0 12 12 12 2 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFO95300.1 - 3.2e-14 52.5 13.9 0.0054 16.5 0.0 11.3 11 2 1 12 12 12 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFO95300.1 - 1.2e-11 44.3 1.2 8.5 6.3 0.0 9.2 10 0 0 10 10 10 2 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.3 KFO95300.1 - 0.019 14.8 0.0 96 2.9 0.0 5.3 6 0 0 6 6 6 0 Natural killer cell receptor 2B4 TGF_beta PF00019.15 KFO95301.1 - 3.9e-17 62.4 2.2 1.9e-12 47.3 0.2 2.3 1 1 1 2 2 2 2 Transforming growth factor beta like domain Connexin PF00029.14 KFO95302.1 - 2.4e-51 172.2 0.3 3.9e-51 171.6 0.2 1.3 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFO95302.1 - 7.7e-22 76.8 1.0 7.7e-22 76.8 0.7 2.5 3 0 0 3 3 3 1 Gap junction channel protein cysteine-rich domain LRR_4 PF12799.2 KFO95303.1 - 3.5e-17 61.6 18.8 8.9e-08 31.5 0.7 5.4 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO95303.1 - 5.7e-11 42.0 19.6 2.7e-06 27.0 3.0 4.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KFO95303.1 - 0.00039 20.0 20.3 2 8.7 0.0 7.2 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.1 KFO95303.1 - 0.00042 19.9 0.4 0.00093 18.7 0.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KFO95303.1 - 0.022 14.8 14.3 3.3 8.0 0.1 6.5 5 1 1 6 6 6 0 Leucine Rich repeat BESS PF02944.15 KFO95303.1 - 0.11 12.0 2.3 0.26 10.8 0.1 2.6 2 0 0 2 2 2 0 BESS motif LRR_7 PF13504.1 KFO95303.1 - 0.86 10.0 15.3 9 6.9 0.1 7.0 8 0 0 8 8 8 0 Leucine rich repeat HCO3_cotransp PF00955.16 KFO95304.1 - 1.1e-230 766.6 26.7 4.3e-139 464.4 8.7 2.3 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.8 KFO95304.1 - 3.6e-105 351.1 0.3 3.6e-105 351.1 0.2 2.6 3 0 0 3 3 3 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.17 KFO95304.1 - 6e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Paf1 PF03985.8 KFO95304.1 - 0.12 11.0 17.5 0.027 13.2 9.2 1.9 2 0 0 2 2 2 0 Paf1 Ribosomal_60s PF00428.14 KFO95304.1 - 2.1 8.7 17.5 2.4 8.6 0.0 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein TRAP_alpha PF03896.11 KFO95304.1 - 6.8 5.5 7.2 1.8 7.5 2.4 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit NPR3 PF03666.8 KFO95304.1 - 7 5.0 12.3 12 4.3 7.5 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Lectin_C PF00059.16 KFO95305.1 - 2.6e-135 442.6 82.2 1.8e-19 70.3 0.6 12.0 11 1 1 12 12 12 10 Lectin C-type domain fn2 PF00040.14 KFO95305.1 - 4.1e-16 58.6 7.8 1e-15 57.4 3.7 3.0 2 0 0 2 2 2 1 Fibronectin type II domain Herpes_UL45 PF05473.7 KFO95305.1 - 6.5e-10 38.7 27.9 0.014 14.8 0.0 10.0 9 2 2 11 11 11 5 UL45 protein PepSY_TM_3 PF13706.1 KFO95305.1 - 0.031 13.6 0.2 0.12 11.8 0.2 2.0 1 0 0 1 1 1 0 PepSY-associated TM helix MARVEL PF01284.18 KFO95305.1 - 0.051 13.4 0.5 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Membrane-associating domain FixQ PF05545.6 KFO95305.1 - 0.39 10.3 3.0 1.1 8.9 2.1 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Integrin_beta PF00362.13 KFO95306.1 - 1.5e-171 571.0 0.0 2.8e-171 570.1 0.0 1.4 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 KFO95306.1 - 3.1e-20 71.2 0.4 5e-20 70.6 0.3 1.3 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 KFO95306.1 - 3.4e-11 43.4 6.4 3.4e-11 43.4 4.5 3.5 3 1 0 3 3 3 1 Integrin beta tail domain EGF_2 PF07974.8 KFO95306.1 - 0.00032 20.8 17.9 0.00032 20.8 12.4 7.0 6 1 1 7 7 7 3 EGF-like domain hEGF PF12661.2 KFO95306.1 - 0.0095 15.9 2.7 0.0095 15.9 1.8 6.0 7 0 0 7 7 7 2 Human growth factor-like EGF RRM_1 PF00076.17 KFO95307.1 - 5.7e-33 112.3 0.0 2.9e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95307.1 - 4.7e-26 90.5 0.0 1.6e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95307.1 - 8.2e-14 51.2 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytadhesin_P30 PF07271.6 KFO95307.1 - 0.015 14.6 1.5 0.028 13.6 1.1 1.5 1 0 0 1 1 1 0 Cytadhesin P30/P32 JAB PF01398.16 KFO95308.1 - 2.5e-35 120.6 0.1 7.2e-35 119.1 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFO95308.1 - 2.1e-31 108.3 4.6 4.3e-31 107.3 3.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KFO95308.1 - 8.4e-08 31.7 0.0 1.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GPAT_N PF14829.1 KFO95308.1 - 0.032 13.9 1.3 0.057 13.1 0.1 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal T-box PF00907.17 KFO95309.1 - 8.1e-15 54.7 0.0 1.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 T-box HCO3_cotransp PF00955.16 KFO95310.1 - 7.2e-245 813.4 6.7 8.9e-245 813.1 4.6 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFO95310.1 - 5.7e-104 347.1 0.0 8.3e-104 346.6 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Hormone_2 PF00123.15 KFO95311.1 - 7.1e-49 163.2 4.3 1.4e-16 59.9 0.5 3.2 3 0 0 3 3 3 3 Peptide hormone SBP_bac_8 PF13416.1 KFO95311.1 - 0.0023 17.7 0.1 9 5.9 0.0 3.1 3 0 0 3 3 3 2 Bacterial extracellular solute-binding protein mIF3 PF14877.1 KFO95311.1 - 0.045 13.1 0.2 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor DPPIV_N PF00930.16 KFO95312.1 - 9e-106 353.4 8.0 1.3e-105 352.8 5.6 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFO95312.1 - 6.7e-56 188.8 1.1 1.1e-55 188.1 0.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFO95312.1 - 5.3e-11 42.4 0.1 1.2e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFO95312.1 - 2.6e-07 30.7 0.0 1.5e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KFO95312.1 - 0.00012 21.6 3.6 0.00058 19.3 0.4 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.9 KFO95312.1 - 0.00044 19.5 0.2 0.001 18.3 0.2 1.5 1 0 0 1 1 1 1 Secretory lipase Esterase_phd PF10503.4 KFO95312.1 - 0.00072 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KFO95312.1 - 0.0017 17.8 1.7 0.11 11.8 0.3 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 KFO95312.1 - 0.0018 17.5 0.4 0.0087 15.3 0.3 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 KFO95312.1 - 0.0024 16.2 0.2 0.27 9.4 0.0 2.9 2 1 1 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.15 KFO95312.1 - 0.0091 15.5 0.5 0.18 11.2 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 KFO95312.1 - 0.027 13.9 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) RIG-I_C-RD PF11648.3 KFO95313.1 - 4.4e-33 113.7 2.4 4.4e-33 113.7 1.7 2.2 2 0 0 2 2 2 1 C-terminal domain of RIG-I DEAD PF00270.24 KFO95313.1 - 1.5e-17 63.6 0.0 3.7e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFO95313.1 - 1.6e-17 63.9 0.0 1.6e-17 63.9 0.0 3.8 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFO95313.1 - 8.1e-17 60.8 0.5 6.9e-16 57.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CARD PF00619.16 KFO95313.1 - 2.7e-09 36.7 0.3 6.2e-07 29.1 0.1 2.8 2 0 0 2 2 2 1 Caspase recruitment domain AAA_22 PF13401.1 KFO95313.1 - 0.00015 21.8 0.1 0.001 19.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Yippee-Mis18 PF03226.9 KFO95313.1 - 0.01 15.8 1.4 0.036 14.0 1.0 2.0 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Adeno_E4 PF05385.6 KFO95313.1 - 0.039 13.9 0.7 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein zf-B_box PF00643.19 KFO95313.1 - 0.72 9.7 5.6 0.53 10.2 0.4 3.1 3 0 0 3 3 3 0 B-box zinc finger Ion_trans PF00520.26 KFO95314.1 - 2.1e-20 72.8 3.8 3.6e-20 72.0 2.6 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 KFO95314.1 - 8.4e-14 51.1 0.0 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 KFO95314.1 - 3.7e-12 45.7 0.0 1.2e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Ion channel BACK PF07707.10 KFO95314.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch AAA PF00004.24 KFO95315.1 - 1.2e-24 87.0 0.0 2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFO95315.1 - 8.1e-05 22.3 0.0 0.0002 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 KFO95315.1 - 0.00031 20.5 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.1 KFO95315.1 - 0.0057 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFO95315.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFO95315.1 - 0.04 14.0 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KFO95315.1 - 0.11 11.1 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus BPS PF08947.5 KFO95316.1 - 1e-27 95.4 0.3 1.8e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.19 KFO95316.1 - 3.4e-17 61.9 0.1 7.1e-17 60.9 0.1 1.6 1 0 0 1 1 1 1 SH2 domain RA PF00788.18 KFO95316.1 - 1.5e-13 51.0 0.1 5.1e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFO95316.1 - 7.9e-08 32.4 0.1 1.8e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFO95316.1 - 0.11 12.7 0.1 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Cobl PF09469.5 KFO95317.1 - 2.2e-31 107.6 1.5 6.7e-31 106.0 1.1 1.9 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain DUF3086 PF11285.3 KFO95317.1 - 0.0049 15.7 0.2 0.012 14.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) TUG-UBL1 PF11470.3 KFO95317.1 - 0.017 14.9 0.5 0.2 11.6 0.1 2.5 2 0 0 2 2 2 0 GLUT4 regulating protein TUG YukD PF08817.5 KFO95317.1 - 0.029 14.9 0.1 0.5 10.9 0.0 2.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD CHDCT2 PF08074.6 KFO95317.1 - 0.11 12.2 0.5 0.22 11.2 0.4 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Aa_trans PF01490.13 KFO95318.1 - 1.3e-63 214.9 29.9 1.5e-63 214.7 20.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFO95318.1 - 2.2e-06 26.7 13.2 2.2e-06 26.7 9.2 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2371 PF10177.4 KFO95318.1 - 0.00022 21.0 1.0 0.0058 16.5 0.0 3.1 3 1 0 3 3 3 1 Uncharacterised conserved protein (DUF2371) DUF485 PF04341.7 KFO95318.1 - 0.12 12.1 0.1 0.12 12.1 0.1 4.6 6 0 0 6 6 6 0 Protein of unknown function, DUF485 DUF2427 PF10348.4 KFO95318.1 - 4.2 7.0 16.6 0.83 9.2 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) Ion_trans PF00520.26 KFO95319.1 - 1.2e-207 684.0 92.8 5e-74 247.8 9.6 5.6 4 1 1 5 5 5 5 Ion transport protein Na_trans_assoc PF06512.8 KFO95319.1 - 2.5e-75 253.5 3.0 2.5e-75 253.5 2.1 3.8 4 0 0 4 4 4 1 Sodium ion transport-associated DUF3451 PF11933.3 KFO95319.1 - 1e-67 228.2 17.1 1e-67 228.2 11.9 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3451) PKD_channel PF08016.7 KFO95319.1 - 4.5e-05 22.0 0.1 4.5e-05 22.0 0.1 9.9 6 4 5 11 11 11 7 Polycystin cation channel IQ PF00612.22 KFO95319.1 - 0.0012 18.2 0.9 0.0033 16.9 0.6 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif TMEM51 PF15345.1 KFO95319.1 - 3.2 7.3 12.6 1.8 8.2 0.8 2.5 2 0 0 2 2 2 0 Transmembrane protein 51 DUF4407 PF14362.1 KFO95319.1 - 6.6 5.5 9.4 21 3.9 6.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glycos_transf_2 PF00535.21 KFO95321.1 - 2.5e-30 105.3 0.0 4.4e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFO95321.1 - 1.4e-25 89.7 0.4 2.2e-25 89.0 0.3 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 KFO95321.1 - 3.8e-11 42.2 0.0 1.4e-10 40.4 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFO95321.1 - 8.6e-10 38.1 0.0 0.001 18.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KFO95321.1 - 1.2e-07 31.7 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GlcNAc PF11397.3 KFO95321.1 - 0.0096 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) RicinB_lectin_2 PF14200.1 KFO95321.1 - 0.069 13.5 0.0 3.6 8.0 0.0 2.7 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Glyco_trans_2_3 PF13632.1 KFO95321.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family group 2 TPR_19 PF14559.1 KFO95322.1 - 2.5e-57 191.1 58.3 6e-08 32.9 1.2 18.2 13 4 8 21 21 19 13 Tetratricopeptide repeat TPR_16 PF13432.1 KFO95322.1 - 1.3e-48 162.6 41.0 6.1e-08 33.1 0.0 18.2 17 4 5 22 22 19 9 Tetratricopeptide repeat TPR_11 PF13414.1 KFO95322.1 - 2e-47 158.7 66.0 6.2e-11 41.7 0.1 17.0 15 3 2 18 18 18 10 TPR repeat TPR_14 PF13428.1 KFO95322.1 - 7.3e-42 138.0 36.9 2.8e-05 24.3 0.0 22.3 13 6 9 23 23 23 6 Tetratricopeptide repeat TPR_2 PF07719.12 KFO95322.1 - 8.8e-42 137.6 68.5 1.2e-05 24.8 0.0 23.1 23 1 1 24 24 23 10 Tetratricopeptide repeat TPR_1 PF00515.23 KFO95322.1 - 2.2e-28 96.6 67.7 3.6e-05 23.1 0.2 19.2 19 0 0 19 19 18 8 Tetratricopeptide repeat Apc3 PF12895.2 KFO95322.1 - 2.1e-27 95.0 58.1 5.2e-07 29.7 1.9 13.0 8 6 7 15 15 15 9 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFO95322.1 - 8.2e-26 87.8 46.9 0.00023 20.6 0.0 16.0 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_12 PF13424.1 KFO95322.1 - 1.3e-23 82.6 61.7 0.0012 18.6 1.8 16.0 10 5 7 17 17 17 11 Tetratricopeptide repeat TPR_7 PF13176.1 KFO95322.1 - 3.1e-20 70.3 38.6 0.00044 19.8 0.0 14.9 16 1 1 17 17 15 6 Tetratricopeptide repeat TPR_17 PF13431.1 KFO95322.1 - 5.4e-18 63.6 24.9 0.013 15.6 0.2 15.4 17 0 0 17 17 15 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFO95322.1 - 1.3e-13 50.3 59.8 0.04 14.3 0.0 19.6 20 0 0 20 20 19 2 Tetratricopeptide repeat TPR_21 PF09976.4 KFO95322.1 - 5.1e-08 32.9 41.8 0.036 14.0 1.2 9.2 6 2 4 11 11 11 4 Tetratricopeptide repeat TPR_4 PF07721.9 KFO95322.1 - 8.4e-06 25.7 20.2 0.035 14.5 1.4 8.9 10 0 0 10 10 6 1 Tetratricopeptide repeat PPR PF01535.15 KFO95322.1 - 8.5e-06 25.4 13.9 88 3.4 0.0 11.9 14 0 0 14 14 12 0 PPR repeat TPR_10 PF13374.1 KFO95322.1 - 1.9e-05 24.4 18.2 0.32 10.9 0.1 9.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFO95322.1 - 3.9e-05 23.4 22.1 0.064 13.1 0.0 8.2 9 2 1 10 10 7 3 Tetratricopeptide repeat PPR_2 PF13041.1 KFO95322.1 - 0.00063 19.6 1.4 38 4.3 0.0 7.3 7 0 0 7 7 6 0 PPR repeat family TPR_20 PF14561.1 KFO95322.1 - 0.00065 19.7 34.2 13 6.0 1.1 11.2 7 2 5 12 12 12 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFO95322.1 - 0.0011 18.8 30.7 0.2 11.5 0.1 10.8 10 1 0 11 11 10 2 Fis1 C-terminal tetratricopeptide repeat PPR_1 PF12854.2 KFO95322.1 - 0.0078 15.6 4.6 27 4.3 0.0 6.5 8 0 0 8 8 8 0 PPR repeat DUF3856 PF12968.2 KFO95322.1 - 0.052 13.3 4.6 7.9 6.2 0.0 4.7 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) SNAP PF14938.1 KFO95322.1 - 2.4 7.2 33.5 0.2 10.8 2.2 6.6 3 2 3 6 6 6 0 Soluble NSF attachment protein, SNAP Ion_trans PF00520.26 KFO95323.1 - 1.6e-216 713.0 100.0 5e-75 251.1 8.0 4.9 5 0 0 5 5 5 4 Ion transport protein Na_trans_assoc PF06512.8 KFO95323.1 - 1.6e-72 244.3 7.0 1.6e-72 244.3 4.8 3.3 3 0 0 3 3 3 1 Sodium ion transport-associated DUF3451 PF11933.3 KFO95323.1 - 1.3e-71 240.9 13.2 1.3e-71 240.9 9.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3451) PKD_channel PF08016.7 KFO95323.1 - 1.3e-08 33.7 81.4 8.9e-05 21.0 0.0 9.3 6 4 3 10 10 10 8 Polycystin cation channel IQ PF00612.22 KFO95323.1 - 0.011 15.2 0.4 0.029 13.9 0.3 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF3138 PF11336.3 KFO95323.1 - 5.3 5.1 8.8 10 4.1 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ion_trans PF00520.26 KFO95324.1 - 1.1e-50 171.6 45.2 3.2e-50 170.1 13.8 3.0 3 1 0 3 3 3 2 Ion transport protein PKD_channel PF08016.7 KFO95324.1 - 6.5e-08 31.4 20.5 9.2e-06 24.3 0.2 3.3 2 1 1 3 3 3 3 Polycystin cation channel IQ PF00612.22 KFO95324.1 - 0.00049 19.4 0.6 0.0013 18.1 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Abhydrolase_6 PF12697.2 KFO95325.1 - 4.7e-16 59.3 0.0 6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFO95325.1 - 1.6e-10 40.9 0.0 7.7e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO95325.1 - 9.1e-08 31.9 0.0 1.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFO95325.1 - 1.9e-05 23.9 0.0 0.023 13.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 KFO95325.1 - 2.5e-05 23.8 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KFO95325.1 - 3.1e-05 23.5 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KFO95325.1 - 6.5e-05 22.5 0.0 0.00015 21.4 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 KFO95325.1 - 0.00062 19.4 0.1 0.0024 17.5 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.13 KFO95325.1 - 0.0015 17.8 0.0 0.026 13.8 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KFO95325.1 - 0.008 16.0 0.4 0.015 15.1 0.3 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KFO95325.1 - 0.015 15.5 0.0 0.039 14.1 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain DUF1350 PF07082.6 KFO95325.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Abhydrolase_3 PF07859.8 KFO95325.1 - 0.04 13.4 0.0 0.084 12.4 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 KFO95325.1 - 0.041 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIP PF03583.9 KFO95325.1 - 0.047 12.8 0.0 0.62 9.2 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase FSH1 PF03959.8 KFO95325.1 - 0.059 12.8 0.0 0.21 10.9 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BTB PF00651.26 KFO95326.1 - 3.9e-44 149.1 2.3 3.4e-21 75.3 0.0 3.4 2 1 1 3 3 3 3 BTB/POZ domain Ank_5 PF13857.1 KFO95326.1 - 5.2e-11 42.4 0.2 7.1e-08 32.4 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFO95326.1 - 5.3e-10 39.4 0.0 1.3e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO95326.1 - 1.4e-08 34.9 0.1 5.4e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KFO95326.1 - 1.6e-08 33.8 0.0 1.9e-06 27.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KFO95326.1 - 5.7e-07 29.1 0.1 0.00027 20.9 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat DUF3342 PF11822.3 KFO95326.1 - 0.0002 20.5 0.6 0.014 14.5 0.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) BACK PF07707.10 KFO95326.1 - 0.00047 19.9 0.2 0.0014 18.4 0.1 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch IFT20 PF14931.1 KFO95326.1 - 0.012 15.5 1.4 0.037 13.9 1.0 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 CCAP PF11105.3 KFO95326.1 - 0.16 11.7 1.4 0.33 10.7 1.0 1.5 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a CD34_antigen PF06365.7 KFO95327.1 - 2.5e-61 206.8 0.0 3.3e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Amnionless PF14828.1 KFO95327.1 - 0.12 10.8 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless Shisa PF13908.1 KFO95327.1 - 0.22 11.6 1.4 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator MCM PF00493.18 KFO95328.1 - 2.1e-141 470.5 0.0 3e-141 470.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KFO95328.1 - 1.7e-26 93.0 22.2 1.7e-26 93.0 15.4 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KFO95328.1 - 1e-19 71.1 0.6 2.9e-19 69.7 0.4 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFO95328.1 - 1.1e-08 34.5 0.0 4.9e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFO95328.1 - 4.7e-07 29.4 0.0 3.4e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFO95328.1 - 8.2e-07 28.8 0.0 2.8e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KFO95328.1 - 0.0018 17.7 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 KFO95328.1 - 0.0025 18.0 0.0 0.0071 16.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KFO95328.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 KFO95328.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sema PF01403.14 KFO95329.1 - 7e-54 182.9 0.0 8.8e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.7 KFO95330.1 - 3e-263 874.0 4.9 3.7e-263 873.7 3.4 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 KFO95330.1 - 3.1e-45 152.0 15.6 7.4e-13 48.3 0.0 5.7 5 0 0 5 5 5 4 IPT/TIG domain PSI PF01437.20 KFO95330.1 - 5.8e-22 77.5 52.9 3.5e-10 39.8 8.7 3.6 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.14 KFO95330.1 - 0.00027 20.6 1.5 0.0057 16.3 1.0 2.3 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF948 PF06103.6 KFO95330.1 - 0.19 11.6 0.3 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0104 PF03706.8 KFO95330.1 - 0.27 10.4 0.0 0.4 9.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) PEGSRP PF07623.6 KFO95330.1 - 0.69 9.2 2.9 1.4 8.2 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Pyr_redox_2 PF07992.9 KFO95331.1 - 3.5e-37 128.2 0.1 4.7e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFO95331.1 - 1.8e-28 98.7 0.0 4.4e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFO95331.1 - 6.6e-16 58.4 3.2 9.7e-13 48.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFO95331.1 - 3.5e-09 37.0 0.0 7.7e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFO95331.1 - 1.6e-07 30.5 0.1 1e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KFO95331.1 - 0.00056 18.4 0.5 0.0012 17.3 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KFO95331.1 - 0.0007 18.7 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFO95331.1 - 0.0011 18.1 0.9 0.0056 15.7 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFO95331.1 - 0.0037 16.2 0.1 0.0037 16.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KFO95331.1 - 0.031 13.1 2.4 0.13 11.0 1.7 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFO95331.1 - 0.044 13.7 0.5 0.044 13.7 0.4 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFO95331.1 - 1.3 7.9 4.1 2 7.4 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Sulfotransfer_2 PF03567.9 KFO95332.1 - 1.6e-69 234.4 3.9 1.8e-69 234.2 2.7 1.0 1 0 0 1 1 1 1 Sulfotransferase family DUF4543 PF15076.1 KFO95332.1 - 0.035 14.1 0.5 0.064 13.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) MgtE PF01769.11 KFO95333.1 - 1.3e-40 138.8 16.6 1.2e-26 93.5 5.9 3.2 4 0 0 4 4 4 2 Divalent cation transporter zf-C2H2 PF00096.21 KFO95334.1 - 1.9e-14 53.0 20.4 2.7e-05 24.2 1.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO95334.1 - 6.5e-13 48.2 20.3 5.4e-09 35.8 0.7 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO95334.1 - 8.5e-12 44.5 18.8 3.5e-05 23.8 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFO95334.1 - 0.0036 17.4 4.6 0.12 12.6 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type DUF2225 PF09986.4 KFO95334.1 - 0.027 13.9 0.3 0.09 12.2 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 KFO95334.1 - 0.047 13.6 2.0 4.5 7.3 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFO95334.1 - 2.3 8.4 7.5 0.4 10.8 0.7 2.3 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KFO95335.1 - 1.3e-13 50.5 39.1 0.00045 20.3 0.0 6.9 6 1 1 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFO95335.1 - 3.4e-13 49.0 46.9 0.00062 19.9 0.2 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO95335.1 - 3e-11 42.8 39.3 0.004 17.3 0.1 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.2 KFO95335.1 - 2.2 8.6 22.1 0.54 10.5 0.8 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type CHCH PF06747.8 KFO95336.1 - 1.4e-07 31.2 3.1 2.6e-07 30.3 2.1 1.5 1 0 0 1 1 1 1 CHCH domain DUF1625 PF07787.7 KFO95337.1 - 2.7e-82 275.7 0.0 3.7e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) BHD_3 PF10405.4 KFO95338.1 - 1.6e-31 107.8 0.0 3.9e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 KFO95338.1 - 6.2e-27 93.7 0.1 6.2e-27 93.7 0.1 3.9 4 1 1 5 5 5 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 KFO95338.1 - 1.1e-18 66.4 0.0 2.9e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFO95338.1 - 1.8e-16 60.1 0.1 1.8e-16 60.1 0.1 3.4 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KFO95338.1 - 0.025 14.7 0.0 0.59 10.3 0.0 2.6 2 0 0 2 2 2 0 Transglutaminase-like superfamily LSM PF01423.17 KFO95339.1 - 1.9e-19 68.9 0.2 2.6e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain vATP-synt_E PF01991.13 KFO95339.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit YfkB PF08756.5 KFO95339.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 YfkB-like domain SNF PF00209.13 KFO95340.1 - 4.5e-236 784.3 37.5 5.2e-236 784.1 26.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PDZ PF00595.19 KFO95341.1 - 2.1e-95 313.0 3.1 4.1e-14 52.5 0.0 7.2 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO95341.1 - 8.2e-41 137.7 0.4 3.4e-05 23.6 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.1 KFO95341.1 - 2.9e-13 49.4 1.5 0.029 14.1 0.0 6.9 6 0 0 6 6 6 4 Tricorn protease PDZ domain GRASP55_65 PF04495.9 KFO95341.1 - 5.2e-05 23.2 0.0 4 7.4 0.0 4.7 4 1 1 5 5 5 2 GRASP55/65 PDZ-like domain EutA PF06277.6 KFO95341.1 - 0.0029 16.2 0.3 0.077 11.5 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA MoaE PF02391.12 KFO95341.1 - 0.0057 16.4 1.3 9.3 6.0 0.0 4.2 5 0 0 5 5 5 2 MoaE protein DUF4078 PF13300.1 KFO95342.1 - 7.6e-23 80.4 8.7 7.6e-23 80.4 6.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Baculo_PEP_C PF04513.7 KFO95343.1 - 0.017 14.9 1.1 0.017 14.9 0.8 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus T2SF PF00482.18 KFO95343.1 - 0.024 14.5 0.4 0.32 10.9 0.2 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Polysacc_deac_2 PF04748.8 KFO95343.1 - 0.041 12.8 0.2 0.14 11.1 0.1 1.8 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase DUF2730 PF10805.3 KFO95343.1 - 0.14 11.8 2.1 1.8 8.3 0.0 3.4 2 1 1 4 4 4 0 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 KFO95343.1 - 0.27 10.3 4.3 0.53 9.4 2.9 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein SseC PF04888.7 KFO95343.1 - 1 8.5 8.2 1.2 8.4 0.4 2.8 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family CorA PF01544.13 KFO95343.1 - 2.3 7.1 10.2 1.7 7.5 1.7 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ACCA PF03255.9 KFO95343.1 - 3.1 7.3 9.5 0.38 10.2 0.1 3.0 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4404 PF14357.1 KFO95343.1 - 5.6 7.4 14.3 0.38 11.1 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) DUF1664 PF07889.7 KFO95343.1 - 5.9 6.7 8.9 3.1 7.6 3.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Plexin_cytopl PF08337.7 KFO95344.1 - 8e-253 839.6 0.0 1e-252 839.2 0.0 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 KFO95344.1 - 6.2e-33 112.6 0.1 2.1e-11 43.6 1.2 5.9 5 1 0 5 5 5 4 IPT/TIG domain Sema PF01403.14 KFO95344.1 - 2.2e-29 102.2 0.0 4.2e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFO95344.1 - 1.2e-14 54.2 53.4 3.1e-09 36.8 10.6 3.7 3 0 0 3 3 3 3 Plexin repeat Pkinase PF00069.20 KFO95345.1 - 5.4e-43 147.0 0.0 6.8e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95345.1 - 3.7e-15 55.7 0.0 2.7e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFO95345.1 - 0.015 14.1 0.1 0.023 13.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KFO95345.1 - 0.19 11.0 0.0 0.45 9.8 0.0 1.5 2 0 0 2 2 2 0 RIO1 family SET PF00856.23 KFO95346.1 - 1.5e-10 41.6 0.1 1.5e-10 41.6 0.1 4.2 3 2 0 3 3 3 1 SET domain Myotub-related PF06602.9 KFO95347.1 - 0.00025 19.9 0.1 0.00047 19.0 0.1 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KFO95347.1 - 0.00081 19.6 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFO95347.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFO95347.1 - 0.12 11.9 0.0 0.97 9.0 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Copine PF07002.11 KFO95348.1 - 4.2e-58 195.2 0.1 6.2e-58 194.6 0.1 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 KFO95348.1 - 4.3e-30 103.3 1.4 4.4e-15 55.2 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFO95348.1 - 1.8e-09 37.7 0.0 3.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VCBS PF13517.1 KFO95348.1 - 0.017 15.4 0.2 0.079 13.3 0.1 2.2 1 1 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-HC5HC2H_2 PF13832.1 KFO95349.1 - 2.5e-39 133.6 7.5 2.5e-39 133.6 5.2 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 KFO95349.1 - 2.9e-32 112.1 8.5 2.9e-32 112.1 5.9 3.2 4 0 0 4 4 4 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 KFO95349.1 - 5.4e-27 93.7 6.4 5.4e-27 93.7 4.4 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 KFO95349.1 - 1.2e-22 79.5 0.8 3e-22 78.3 0.6 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 KFO95349.1 - 1e-14 53.5 3.2 1e-14 53.5 2.2 2.7 2 1 0 2 2 2 1 PHD-finger PWWP PF00855.12 KFO95349.1 - 1.6e-13 50.6 0.0 1.6e-13 50.6 0.0 2.5 3 0 0 3 3 3 1 PWWP domain PHD PF00628.24 KFO95349.1 - 2.2e-08 33.6 27.2 1.8e-06 27.5 8.8 2.9 2 0 0 2 2 2 2 PHD-finger Pkinase PF00069.20 KFO95350.1 - 3.7e-76 255.7 0.0 4.6e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95350.1 - 2.7e-36 124.9 0.0 3.5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO95350.1 - 5.4e-07 28.8 0.0 6.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFO95350.1 - 0.0013 18.1 0.1 0.0025 17.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFO95350.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFO95350.1 - 0.0022 17.3 0.0 0.0048 16.2 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KFO95350.1 - 0.016 14.9 0.0 0.05 13.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ada3 PF10198.4 KFO95351.1 - 1.6e-29 102.2 10.8 3.4e-29 101.2 7.5 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 PaaSYMP PF14738.1 KFO95351.1 - 0.56 9.9 15.9 0.26 10.9 9.0 1.8 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 SUZ PF12752.2 KFO95351.1 - 3.8 8.1 8.1 0.66 10.5 0.7 3.1 3 0 0 3 3 3 0 SUZ domain TBPIP PF07106.8 KFO95351.1 - 4 6.9 11.4 4.4 6.8 6.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ARPC4 PF05856.7 KFO95352.1 - 4.2e-51 172.6 5.0 4.6e-51 172.5 3.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) TTL PF03133.10 KFO95353.1 - 3.2e-71 239.6 0.0 1.2e-69 234.4 0.0 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFO95353.1 - 0.049 12.4 0.0 5.8 5.6 0.0 2.4 3 0 0 3 3 3 0 YheC/D like ATP-grasp PDDEXK_1 PF12705.2 KFO95353.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily CP_ATPgrasp_1 PF04174.8 KFO95353.1 - 0.08 11.5 0.0 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 A circularly permuted ATPgrasp PseudoU_synth_2 PF00849.17 KFO95354.1 - 9.7e-07 28.7 0.0 1.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF1352 PF07086.7 KFO95355.1 - 1.9e-90 301.5 3.7 2.1e-90 301.3 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1352) Kelch_1 PF01344.20 KFO95358.1 - 8.1e-46 153.3 0.0 1.4e-07 30.9 0.0 7.4 8 0 0 8 8 8 7 Kelch motif Kelch_6 PF13964.1 KFO95358.1 - 2.8e-38 128.5 1.8 1.5e-07 31.2 0.0 7.4 3 3 4 7 7 7 6 Kelch motif Kelch_4 PF13418.1 KFO95358.1 - 3e-35 119.7 0.7 6.7e-07 28.9 0.1 7.3 5 2 2 7 7 7 7 Galactose oxidase, central domain Kelch_3 PF13415.1 KFO95358.1 - 6.7e-32 108.9 1.9 7e-07 29.2 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFO95358.1 - 3.2e-19 67.8 0.4 0.0028 17.3 0.0 7.8 7 1 0 7 7 7 5 Kelch motif Kelch_5 PF13854.1 KFO95358.1 - 8.5e-10 38.3 1.4 0.0031 17.4 0.0 5.9 7 0 0 7 7 7 1 Kelch motif DUF1668 PF07893.8 KFO95358.1 - 0.1 11.7 3.2 0.072 12.2 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1668) CCDC71L PF15374.1 KFO95360.1 - 2.3e-149 497.8 14.0 2.6e-149 497.6 9.7 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 71L SNF PF00209.13 KFO95361.1 - 1.4e-186 621.0 27.4 1.6e-186 620.8 19.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family tRNA-synt_1c PF00749.16 KFO95362.1 - 2.4e-109 364.8 0.0 3.2e-109 364.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFO95362.1 - 5.3e-49 166.2 0.0 1.1e-48 165.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 KFO95362.1 - 2e-36 125.0 0.0 5.4e-36 123.5 0.0 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 KFO95362.1 - 7.6e-24 84.2 1.6 1.4e-23 83.4 1.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 V-SNARE PF05008.10 KFO95362.1 - 0.13 12.4 0.2 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus HTH_psq PF05225.11 KFO95362.1 - 0.14 11.7 0.0 4.3 6.9 0.0 2.4 2 0 0 2 2 2 0 helix-turn-helix, Psq domain DUF3504 PF12012.3 KFO95363.1 - 1e-64 217.4 0.9 1e-64 217.4 0.6 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3504) CARD PF00619.16 KFO95363.1 - 0.0012 18.6 0.0 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 Caspase recruitment domain IMPDH PF00478.20 KFO95364.1 - 3.6e-136 453.6 3.0 4.1e-136 453.5 2.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KFO95364.1 - 3.8e-19 68.1 0.1 5.8e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KFO95364.1 - 3.6e-16 59.2 0.3 5.9e-11 42.0 0.2 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KFO95364.1 - 3.3e-10 39.3 0.6 5.3e-10 38.6 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KFO95364.1 - 2.7e-06 26.8 1.2 0.00044 19.5 0.0 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein NanE PF04131.9 KFO95364.1 - 2.8e-06 26.4 0.2 6.2e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 KFO95364.1 - 0.00035 19.7 2.1 0.00084 18.4 0.7 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KFO95364.1 - 0.0018 17.2 0.7 0.0032 16.4 0.5 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.12 KFO95364.1 - 0.0058 15.5 0.9 0.43 9.3 0.0 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Aldolase PF01081.14 KFO95364.1 - 0.01 15.0 0.7 0.8 8.8 0.0 2.8 3 0 0 3 3 3 0 KDPG and KHG aldolase B12-binding PF02310.14 KFO95364.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Response_reg PF00072.19 KFO95364.1 - 0.031 14.2 0.1 0.084 12.8 0.1 1.8 1 1 0 1 1 1 0 Response regulator receiver domain DUF561 PF04481.7 KFO95364.1 - 0.041 12.8 0.3 0.081 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DHO_dh PF01180.16 KFO95364.1 - 0.17 10.7 3.8 0.11 11.3 0.2 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF498 PF04430.9 KFO95365.1 - 2.5e-27 94.6 0.0 2.7e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DALR_1 PF05746.10 KFO95366.1 - 2.4e-20 72.6 0.0 4.2e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain WD40 PF00400.27 KFO95367.1 - 9e-18 63.4 12.1 0.00081 19.1 0.1 9.5 9 0 0 9 9 9 6 WD domain, G-beta repeat Nsp3_PL2pro PF12124.3 KFO95367.1 - 0.0011 18.4 0.1 0.0079 15.7 0.0 2.5 3 0 0 3 3 3 1 Coronavirus polyprotein cleavage domain EF-hand_7 PF13499.1 KFO95368.1 - 8.3e-09 35.4 0.0 3.3e-08 33.5 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain pair 2OG-FeII_Oxy_3 PF13640.1 KFO95368.1 - 1.5e-07 31.8 0.0 3.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_1 PF00036.27 KFO95368.1 - 2.8e-07 29.3 0.0 0.0086 15.3 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFO95368.1 - 1.5e-06 27.5 0.8 0.018 14.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain 2OG-FeII_Oxy PF03171.15 KFO95368.1 - 2.7e-06 27.5 0.1 1.1e-05 25.5 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EF-hand_5 PF13202.1 KFO95368.1 - 4e-06 25.9 0.1 0.047 13.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFO95368.1 - 3.6e-05 23.2 0.0 0.019 14.5 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair 2OG-FeII_Oxy_4 PF13661.1 KFO95368.1 - 0.03 13.9 0.8 0.098 12.3 0.6 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fz PF01392.17 KFO95369.1 - 9e-32 109.8 7.0 2.1e-31 108.6 4.9 1.6 1 0 0 1 1 1 1 Fz domain NTR PF01759.16 KFO95369.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 UNC-6/NTR/C345C module IBR PF01485.16 KFO95370.1 - 3.4e-22 78.0 43.0 2.2e-13 49.8 4.7 3.7 3 0 0 3 3 3 3 IBR domain zf-C3HC4 PF00097.20 KFO95370.1 - 0.001 18.6 6.2 0.001 18.6 4.3 4.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO95370.1 - 0.0018 18.2 9.0 0.0018 18.2 6.3 4.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO95370.1 - 0.0062 16.3 11.4 0.0062 16.3 7.9 4.0 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 KFO95370.1 - 0.14 11.8 44.5 0.074 12.7 6.8 3.8 3 0 0 3 3 3 0 zinc-RING finger domain DUF2500 PF10694.4 KFO95370.1 - 0.75 9.8 3.2 0.47 10.4 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Mito_carr PF00153.22 KFO95371.1 - 4.6e-60 199.3 1.7 4.3e-22 77.6 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein cNMP_binding PF00027.24 KFO95372.1 - 8e-43 144.1 0.1 1.4e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF627 PF04781.7 KFO95372.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF627) ComC PF03047.9 KFO95373.1 - 0.037 13.4 0.1 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 COMC family RNase_P_Rpp14 PF01900.14 KFO95374.1 - 6e-10 38.9 0.0 6.1e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family MaoC_dehydratas PF01575.14 KFO95375.1 - 7.9e-22 76.9 0.0 1e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KFO95375.1 - 8.2e-07 28.8 0.0 2.4e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 KFO95375.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.7 1 1 0 1 1 1 1 Thioesterase superfamily PX PF00787.19 KFO95376.1 - 1.7e-16 60.0 1.4 7.7e-16 57.8 0.0 2.8 3 0 0 3 3 3 1 PX domain Pkinase PF00069.20 KFO95376.1 - 5.3e-12 45.4 0.0 1.4e-10 40.8 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95376.1 - 1.3e-08 34.2 0.0 8.9e-07 28.2 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase WH2 PF02205.15 KFO95376.1 - 6.6e-08 31.9 0.1 1.4e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 WH2 motif DUF605 PF04652.11 KFO95376.1 - 5.2 6.3 21.2 7.1 5.9 14.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 KFO95376.1 - 5.9 6.3 11.8 9.2 5.6 8.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Gag_spuma PF03276.9 KFO95376.1 - 8.1 4.6 10.2 12 4.0 7.1 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Transket_pyr PF02779.19 KFO95377.1 - 3.6e-44 150.3 0.0 7e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFO95377.1 - 8.8e-33 112.8 0.3 7.4e-32 109.8 0.2 2.4 1 1 0 1 1 1 1 Transketolase, C-terminal domain BTB_2 PF02214.17 KFO95378.1 - 9.3e-22 77.0 0.0 2.3e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain ACOX PF01756.14 KFO95379.1 - 1.6e-61 206.9 1.6 3.4e-61 205.9 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KFO95379.1 - 1.6e-27 96.3 0.1 2.9e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KFO95379.1 - 6.7e-07 28.7 0.1 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFO95379.1 - 3.4e-06 27.2 0.0 8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1151 PF06625.6 KFO95380.1 - 4.3e-39 133.0 11.4 4.7e-39 132.8 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) ATP-synt_E PF05680.7 KFO95380.1 - 4.7 7.2 6.0 2.8 7.9 3.0 1.5 1 1 1 2 2 2 0 ATP synthase E chain HIT PF01230.18 KFO95382.1 - 7.5e-18 64.8 0.0 8.2e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFO95382.1 - 0.00022 21.4 0.0 0.00026 21.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4570 PF15134.1 KFO95384.1 - 1.9e-42 143.5 2.5 2.2e-42 143.3 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) Vps5 PF09325.5 KFO95384.1 - 0.69 9.1 5.2 0.19 10.9 1.8 1.3 2 0 0 2 2 2 0 Vps5 C terminal like zf-H2C2_2 PF13465.1 KFO95385.1 - 5.4e-22 76.9 29.1 2.6e-06 27.4 2.9 4.1 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFO95385.1 - 4e-20 70.8 28.2 5.7e-07 29.5 1.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO95385.1 - 1.5e-13 50.0 23.4 0.00035 20.7 0.7 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO95385.1 - 3.8e-08 33.2 23.1 0.014 15.5 0.8 4.5 3 1 1 4 4 4 4 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 KFO95385.1 - 5.9e-05 22.7 18.4 0.00012 21.7 2.9 3.2 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.1 KFO95385.1 - 0.00011 22.0 22.0 0.041 13.7 0.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.7 KFO95385.1 - 0.00019 21.4 13.9 0.016 15.2 2.4 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFO95385.1 - 0.0025 17.9 21.3 0.65 10.2 0.3 4.4 3 1 0 4 4 4 1 Zinc-finger of C2H2 type XPA_N PF01286.13 KFO95385.1 - 0.0027 17.3 9.9 2 8.1 0.0 4.2 4 0 0 4 4 4 1 XPA protein N-terminal Prok-RING_1 PF14446.1 KFO95385.1 - 0.006 16.2 10.7 8.4 6.2 0.1 4.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 FYDLN_acid PF09538.5 KFO95385.1 - 0.018 15.6 1.5 14 6.2 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-Sec23_Sec24 PF04810.10 KFO95385.1 - 0.027 14.0 11.9 0.3 10.6 1.3 3.9 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger BolA PF01722.13 KFO95385.1 - 0.047 13.6 1.1 5.5 7.0 0.1 2.6 2 1 1 3 3 3 0 BolA-like protein C1_3 PF07649.7 KFO95385.1 - 0.077 13.0 13.3 0.38 10.8 0.0 4.3 4 1 0 4 4 4 0 C1-like domain zf-CHY PF05495.7 KFO95385.1 - 0.078 13.1 15.9 0.07 13.2 1.6 2.4 1 1 0 2 2 2 0 CHY zinc finger Zn-ribbon_8 PF09723.5 KFO95385.1 - 0.095 12.6 17.4 8.4 6.4 0.2 4.0 2 1 2 4 4 4 0 Zinc ribbon domain Rep_fac-A_C PF08646.5 KFO95385.1 - 0.23 11.1 11.0 1.1 8.9 0.4 2.4 1 1 2 3 3 3 0 Replication factor-A C terminal domain Rubredoxin PF00301.15 KFO95385.1 - 0.23 11.3 6.3 28 4.6 0.1 3.9 4 0 0 4 4 4 0 Rubredoxin zf-CCHC_5 PF14787.1 KFO95385.1 - 0.54 9.7 17.7 1.2 8.6 0.4 3.9 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger Ribosomal_L31 PF01197.13 KFO95385.1 - 0.56 10.2 6.5 67 3.5 4.5 3.0 1 1 0 1 1 1 0 Ribosomal protein L31 zf-BED PF02892.10 KFO95385.1 - 0.59 9.9 28.5 0.085 12.6 2.6 4.2 2 2 2 4 4 4 0 BED zinc finger zf-C3HC4_3 PF13920.1 KFO95385.1 - 0.65 9.7 13.0 1.2e+03 -0.8 9.0 3.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.6 KFO95385.1 - 0.71 9.5 5.5 7.5 6.2 0.2 3.1 1 1 3 4 4 4 0 GAGA factor zf-RING_3 PF14369.1 KFO95385.1 - 0.71 9.9 11.4 9.7 6.2 0.2 4.0 4 0 0 4 4 4 0 zinc-finger zf-HIT PF04438.11 KFO95385.1 - 0.76 9.4 16.3 6.5 6.4 0.2 4.2 4 0 0 4 4 4 0 HIT zinc finger zf-FCS PF06467.9 KFO95385.1 - 0.94 9.1 19.4 1 9.0 0.3 4.2 3 1 1 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_2 PF12756.2 KFO95385.1 - 1.8 8.7 17.8 14 5.8 2.0 3.9 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Fer4_11 PF13247.1 KFO95385.1 - 3.1 7.7 9.0 6.3 6.7 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain DZR PF12773.2 KFO95385.1 - 3.5 7.5 15.8 1e+03 -0.4 10.9 2.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KFO95385.1 - 4.5 7.1 22.4 1.6 8.6 4.1 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain FYVE PF01363.16 KFO95385.1 - 4.7 7.1 20.8 15 5.5 0.4 3.3 1 1 1 2 2 2 0 FYVE zinc finger LIM PF00412.17 KFO95385.1 - 5.2 7.2 17.8 13 5.9 2.6 3.9 1 1 2 3 3 3 0 LIM domain SprT-like PF10263.4 KFO95385.1 - 5.5 6.6 11.7 35 4.0 7.5 2.0 1 1 0 1 1 1 0 SprT-like family DUF2256 PF10013.4 KFO95385.1 - 6.1 6.6 12.8 35 4.2 0.2 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) HypA PF01155.14 KFO95385.1 - 6.4 6.5 10.7 15 5.3 3.0 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Desulfoferrod_N PF06397.7 KFO95385.1 - 7.9 5.9 15.9 7.1 6.0 0.2 4.1 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain MARVEL PF01284.18 KFO95386.1 - 1.5e-36 125.3 6.0 1.9e-36 125.0 4.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Frizzled PF01534.12 KFO95386.1 - 0.0017 17.2 2.2 0.0073 15.1 1.6 1.9 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF588 PF04535.7 KFO95386.1 - 0.0051 16.3 1.5 0.0074 15.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF588) DUF1129 PF06570.6 KFO95386.1 - 0.072 12.3 0.2 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) S_100 PF01023.14 KFO95387.1 - 0.001 18.3 0.0 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_8 PF13833.1 KFO95387.1 - 0.0017 17.9 0.0 0.11 12.1 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFO95387.1 - 0.043 13.1 0.2 0.34 10.3 0.1 2.3 2 0 0 2 2 2 0 EF hand LMP PF04778.7 KFO95387.1 - 0.048 13.4 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 LMP repeated region EF-hand_7 PF13499.1 KFO95387.1 - 0.061 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair THOC7 PF05615.8 KFO95388.1 - 8.7e-41 139.4 2.0 8.7e-41 139.4 1.4 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 UPF0193 PF05250.6 KFO95388.1 - 0.00059 19.4 5.7 0.00059 19.4 3.9 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) DUF641 PF04859.7 KFO95388.1 - 0.0086 15.8 11.3 0.17 11.6 2.9 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF641) Spc7 PF08317.6 KFO95388.1 - 0.064 11.9 16.7 0.019 13.6 3.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein NRN1 PF15056.1 KFO95388.1 - 0.075 12.9 0.4 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 Neuritin protein family DUF479 PF04336.7 KFO95388.1 - 0.28 11.3 3.0 0.3 11.2 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF479 DUF607 PF04678.8 KFO95388.1 - 0.35 10.7 9.3 0.069 13.0 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF607 NPV_P10 PF05531.7 KFO95388.1 - 0.46 10.7 3.0 5.7 7.2 1.6 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.6 KFO95388.1 - 0.55 10.4 13.4 3.7 7.7 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) V_ATPase_I PF01496.14 KFO95388.1 - 1.1 6.9 11.0 1.4 6.6 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 KFO95388.1 - 1.3 8.8 9.7 6.3 6.6 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 KFO95388.1 - 2.4 8.0 12.5 0.3 10.9 1.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AATF-Che1 PF13339.1 KFO95388.1 - 2.6 8.2 14.3 5.5 7.1 4.4 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4168 PF13767.1 KFO95388.1 - 6.1 7.5 10.8 33 5.2 7.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) SCA7 PF08313.7 KFO95389.1 - 1e-27 95.4 3.1 1e-27 95.4 2.1 2.5 2 1 0 2 2 2 1 SCA7, zinc-binding domain DUF3505 PF12013.3 KFO95389.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) RPN7 PF10602.4 KFO95390.1 - 5.3e-63 211.5 2.4 7.6e-63 211.0 1.6 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFO95390.1 - 1.7e-18 66.8 0.3 4.4e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain DUF1732 PF08340.6 KFO95390.1 - 0.039 13.7 1.3 4.4 7.2 0.4 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF1732) TSP_1 PF00090.14 KFO95391.1 - 1.6e-07 31.3 21.0 0.00042 20.3 2.1 2.1 2 0 0 2 2 2 2 Thrombospondin type 1 domain PTN_MK_N PF05196.8 KFO95391.1 - 4.3 7.3 10.5 0.54 10.2 4.1 1.9 1 1 1 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain rve PF00665.21 KFO95392.1 - 3.8e-25 88.3 0.1 5.6e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.19 KFO95392.1 - 2.9e-07 30.9 0.0 5.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNase H Integrase_Zn PF02022.14 KFO95392.1 - 7.1e-07 28.5 0.3 7.1e-07 28.5 0.2 1.6 2 0 0 2 2 2 1 Integrase Zinc binding domain rve_3 PF13683.1 KFO95392.1 - 0.0062 16.0 0.0 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KFO95392.1 - 0.0091 15.9 0.1 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 DDE domain UCR_UQCRX_QCR9 PF05365.7 KFO95392.1 - 0.012 15.1 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Dynactin_p22 PF07426.6 KFO95392.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 Neur PF00064.13 KFO95393.1 - 0.015 13.3 0.0 0.018 13.1 0.0 1.0 1 0 0 1 1 1 0 Neuraminidase KASH PF10541.4 KFO95393.1 - 0.17 11.7 1.1 0.28 11.0 0.8 1.5 1 1 0 1 1 1 0 Nuclear envelope localisation domain 7tm_2 PF00002.19 KFO95397.1 - 3.7e-65 219.3 17.3 5.2e-65 218.9 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TSP_1 PF00090.14 KFO95397.1 - 7e-50 166.9 87.5 2.4e-13 49.9 4.9 6.6 6 0 0 6 6 6 5 Thrombospondin type 1 domain DUF3497 PF12003.3 KFO95397.1 - 1.2e-43 149.0 0.2 1.7e-42 145.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3497) NDUF_B12 PF08122.7 KFO95397.1 - 0.035 13.8 0.2 0.096 12.4 0.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF3422 PF11902.3 KFO95397.1 - 0.17 10.7 0.1 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Fox-1_C PF12414.3 KFO95400.1 - 2.2e-23 82.4 4.8 8.9e-23 80.5 1.8 2.5 2 0 0 2 2 2 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 KFO95400.1 - 7.2e-19 67.1 0.1 1.1e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95400.1 - 1.7e-15 56.7 0.1 2.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95400.1 - 5.7e-11 42.0 0.1 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECM1 PF05782.6 KFO95400.1 - 0.016 13.9 0.5 0.024 13.3 0.3 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) RRM_3 PF08777.6 KFO95400.1 - 0.069 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Globin PF00042.17 KFO95401.1 - 2.1e-23 82.7 0.2 3.8e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Globin TPR_8 PF13181.1 KFO95401.1 - 0.029 14.1 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF294_C PF10335.4 KFO95401.1 - 0.072 12.7 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Ras PF00071.17 KFO95402.1 - 4.1e-40 136.8 0.0 6.2e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95402.1 - 5.5e-16 59.1 0.0 1.2e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO95402.1 - 4.3e-08 32.5 0.0 5.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO95402.1 - 7.5e-05 22.2 0.0 0.00022 20.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFO95402.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFO95402.1 - 0.0045 16.1 0.2 0.0061 15.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 KFO95402.1 - 0.017 14.8 0.1 0.038 13.6 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase SRPRB PF09439.5 KFO95402.1 - 0.02 14.1 0.1 0.12 11.5 0.0 1.9 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AICARFT_IMPCHas PF01808.13 KFO95402.1 - 0.067 12.2 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme AAA_14 PF13173.1 KFO95402.1 - 0.077 12.8 0.2 0.45 10.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFO95402.1 - 0.14 12.3 0.0 6.8 6.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain MCM PF00493.18 KFO95403.1 - 2e-135 450.8 0.2 2.9e-135 450.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFO95403.1 - 1.4e-22 80.4 0.2 4e-22 78.9 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFO95403.1 - 1.2e-06 27.8 0.0 0.00049 19.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFO95403.1 - 0.00048 19.8 0.0 0.0017 18.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFO95403.1 - 0.0058 16.2 0.0 0.022 14.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFO95403.1 - 0.027 13.9 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TrmB PF01978.14 KFO95403.1 - 0.028 14.1 1.4 0.51 10.0 0.3 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Heme_oxygenase PF01126.15 KFO95404.1 - 8.3e-79 263.9 2.1 1.1e-78 263.4 1.5 1.1 1 0 0 1 1 1 1 Heme oxygenase ssDNA-exonuc_C PF10141.4 KFO95404.1 - 0.057 12.9 1.6 0.061 12.8 0.1 1.7 2 0 0 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain VHS PF00790.14 KFO95405.1 - 3.2e-45 153.2 0.0 5.5e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KFO95405.1 - 3.7e-32 110.3 0.9 7.8e-32 109.2 0.6 1.6 1 0 0 1 1 1 1 GAT domain Homeobox PF00046.24 KFO95406.1 - 3.7e-24 84.0 4.3 5.1e-24 83.6 3.0 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO95406.1 - 0.0038 16.9 0.1 0.0083 15.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HA PF03457.9 KFO95406.1 - 0.18 11.9 6.5 0.096 12.8 0.9 2.2 1 1 1 2 2 2 0 Helicase associated domain QLQ PF08880.6 KFO95406.1 - 0.19 11.1 0.5 0.35 10.3 0.4 1.4 1 0 0 1 1 1 0 QLQ Glyco_transf_49 PF13896.1 KFO95407.1 - 6.4e-52 176.6 2.0 6.4e-42 143.7 1.0 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.15 KFO95407.1 - 2.9e-20 72.6 0.4 6.8e-20 71.4 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_2 PF10111.4 KFO95407.1 - 0.0021 17.1 0.0 0.0071 15.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Mto2_bdg PF12808.2 KFO95407.1 - 0.49 10.5 6.2 0.17 12.0 2.0 2.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Synapsin_C PF02750.9 KFO95408.1 - 2.2e-124 412.2 0.4 2.8e-124 411.9 0.3 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 KFO95408.1 - 8.8e-46 154.3 0.1 2e-45 153.2 0.1 1.6 1 0 0 1 1 1 1 Synapsin, N-terminal domain RimK PF08443.6 KFO95408.1 - 1.3e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TIMP PF00965.12 KFO95409.1 - 3.9e-65 218.8 8.5 4.7e-65 218.5 5.9 1.1 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 KFO95409.1 - 0.00024 20.6 1.0 0.00047 19.6 0.7 1.6 1 0 0 1 1 1 1 UNC-6/NTR/C345C module PI31_Prot_N PF11566.3 KFO95410.1 - 5.6e-22 77.9 0.0 1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal F-box-like PF12937.2 KFO95410.1 - 1.2e-10 40.8 2.7 2.3e-10 40.0 1.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFO95410.1 - 1.7e-05 24.3 1.4 3.2e-05 23.4 1.0 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KFO95410.1 - 0.01 16.1 0.4 0.025 14.9 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A HLH PF00010.21 KFO95411.1 - 1.3e-17 63.2 1.8 2e-17 62.5 1.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Muted PF14942.1 KFO95411.1 - 0.088 12.6 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Sbi-IV PF11621.3 KFO95411.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI zf-H2C2_2 PF13465.1 KFO95412.1 - 2.3e-28 97.0 55.2 4.1e-08 33.1 0.6 8.5 8 1 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFO95412.1 - 2.8e-21 74.5 65.8 2.9e-05 24.1 1.2 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO95412.1 - 2.6e-17 61.7 57.9 0.00084 19.4 0.6 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-met PF12874.2 KFO95412.1 - 4.2e-07 29.9 43.2 0.00033 20.7 0.8 7.7 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO95412.1 - 3.6e-05 23.7 49.9 0.025 14.7 0.1 7.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KFO95412.1 - 0.01 15.2 0.3 0.01 15.2 0.2 4.4 2 1 3 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 KFO95412.1 - 0.02 14.7 0.4 0.02 14.7 0.3 7.2 8 0 0 8 8 7 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFO95412.1 - 0.068 13.4 0.6 0.068 13.4 0.4 7.4 7 0 0 7 7 7 0 C2H2-type zinc-finger domain DUF3368 PF11848.3 KFO95412.1 - 0.26 10.8 0.0 0.5 9.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Ecl1 PF12855.2 KFO95412.1 - 0.98 8.7 6.4 8.2 5.8 0.1 4.0 4 0 0 4 4 4 0 Life-span regulatory factor zf-C2H2_2 PF12756.2 KFO95412.1 - 1.1 9.4 37.0 6.2 6.9 7.1 5.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Mu-like_Com PF10122.4 KFO95412.1 - 3.2 6.8 12.0 1.3 8.1 4.6 3.0 2 1 0 2 2 2 0 Mu-like prophage protein Com zf-met2 PF12907.2 KFO95412.1 - 9 6.3 20.7 8.4 6.4 0.1 5.4 5 1 0 5 5 5 0 Zinc-binding WD40 PF00400.27 KFO95413.1 - 2.9e-23 80.8 2.8 4.8e-08 32.5 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Ank PF00023.25 KFO95414.1 - 4.7e-27 92.4 1.1 9.4e-10 37.8 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KFO95414.1 - 1.2e-26 92.8 0.1 2.5e-13 50.1 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) BTB PF00651.26 KFO95414.1 - 2.1e-23 82.4 0.3 1.2e-21 76.7 0.1 3.3 2 1 1 3 3 3 1 BTB/POZ domain Ank_3 PF13606.1 KFO95414.1 - 4.2e-19 66.7 1.2 1.4e-05 24.8 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KFO95414.1 - 5.8e-18 64.8 0.0 1.9e-05 25.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO95414.1 - 7.5e-18 64.1 0.5 0.00014 22.0 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) BACK PF07707.10 KFO95414.1 - 0.00054 19.7 1.0 0.0024 17.6 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch FAD_binding_7 PF03441.9 KFO95415.1 - 2.8e-105 351.4 0.1 3.6e-105 351.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFO95415.1 - 9.3e-25 87.2 0.0 1.9e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase mTERF PF02536.9 KFO95416.1 - 8.8e-19 67.2 7.3 1.2e-18 66.8 5.1 1.2 1 0 0 1 1 1 1 mTERF RRF_GI PF12614.3 KFO95416.1 - 0.021 14.6 0.8 0.063 13.0 0.6 1.8 1 0 0 1 1 1 0 Ribosome recycling factor DUF4332 PF14229.1 KFO95416.1 - 0.056 13.4 0.6 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) HTH_11 PF08279.7 KFO95416.1 - 0.079 12.6 0.1 0.32 10.6 0.0 2.1 1 0 0 1 1 1 0 HTH domain UPF0444 PF15475.1 KFO95417.1 - 7.2e-46 154.1 13.6 8.4e-46 153.9 9.4 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Ric8 PF10165.4 KFO95418.1 - 2.9e-139 464.7 3.5 3.6e-139 464.4 2.4 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 KFO95418.1 - 0.0079 15.1 0.2 0.016 14.2 0.2 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal RFX_DNA_binding PF02257.10 KFO95419.1 - 1e-34 118.5 0.0 4.4e-34 116.4 0.0 2.2 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFO95419.1 - 9e-05 22.6 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like RNA_pol_Rpb2_6 PF00562.23 KFO95420.1 - 2.1e-125 418.5 0.0 1.2e-124 415.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFO95420.1 - 2.6e-54 183.2 1.6 3.7e-54 182.7 0.6 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KFO95420.1 - 9.5e-32 109.1 0.2 3.7e-31 107.2 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KFO95420.1 - 5.4e-28 97.7 1.5 6.4e-28 97.4 0.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KFO95420.1 - 6.1e-23 80.3 1.0 8.2e-22 76.7 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KFO95420.1 - 1.7e-22 79.0 0.5 4.6e-22 77.5 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KFO95420.1 - 1.5e-13 50.5 2.3 1.5e-13 50.5 1.6 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 5 Tcp11 PF05794.8 KFO95421.1 - 1.3e-133 446.0 0.8 1.6e-133 445.6 0.6 1.1 1 0 0 1 1 1 1 T-complex protein 11 RAP1 PF07218.6 KFO95421.1 - 3.2 5.7 7.8 2.2 6.2 3.3 1.9 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Reo_sigmaC PF04582.7 KFO95422.1 - 7e-06 25.4 32.2 0.0028 16.9 7.3 4.8 1 1 3 4 4 4 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFO95422.1 - 8.6e-06 24.5 43.2 0.0024 16.4 16.0 3.0 1 1 2 3 3 3 3 AAA domain Filament PF00038.16 KFO95422.1 - 2.5e-05 23.9 44.8 0.12 11.7 0.9 4.1 1 1 2 4 4 4 4 Intermediate filament protein Tropomyosin PF00261.15 KFO95422.1 - 5.5e-05 22.3 46.7 0.0079 15.3 7.9 5.1 2 2 3 5 5 5 2 Tropomyosin Baculo_PEP_C PF04513.7 KFO95422.1 - 5.7e-05 22.9 33.5 0.024 14.4 4.9 5.1 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KFO95422.1 - 0.00019 21.0 47.8 0.0005 19.7 1.9 4.4 1 1 2 3 3 3 1 IncA protein Tropomyosin_1 PF12718.2 KFO95422.1 - 0.00026 20.8 13.9 0.00026 20.8 9.7 4.8 2 2 2 4 4 4 2 Tropomyosin like GAS PF13851.1 KFO95422.1 - 0.0017 17.6 49.1 0.0097 15.1 9.5 4.5 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KFO95422.1 - 0.0018 18.4 44.7 0.069 13.2 1.5 4.9 1 1 3 5 5 5 4 Fibrinogen alpha/beta chain family EzrA PF06160.7 KFO95422.1 - 0.0063 14.7 40.7 0.19 9.8 7.7 4.7 1 1 2 4 4 4 3 Septation ring formation regulator, EzrA BLOC1_2 PF10046.4 KFO95422.1 - 0.01 15.9 0.8 0.01 15.9 0.5 6.8 1 1 4 6 6 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 KFO95422.1 - 0.01 16.0 37.1 0.068 13.4 1.7 7.1 2 2 5 7 7 7 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 KFO95422.1 - 0.011 15.5 39.6 0.049 13.5 1.1 6.2 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 KFO95422.1 - 0.023 14.5 54.1 0.052 13.4 0.7 5.1 1 1 2 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 KFO95422.1 - 0.032 14.6 37.7 0.57 10.6 2.6 5.9 2 1 4 6 6 6 0 Syntaxin 6, N-terminal DUF869 PF05911.6 KFO95422.1 - 0.067 11.4 48.8 0.15 10.2 1.9 3.1 1 1 1 3 3 3 0 Plant protein of unknown function (DUF869) Cob_adeno_trans PF01923.13 KFO95422.1 - 0.068 12.9 20.0 0.58 9.9 0.3 5.1 1 1 2 5 5 5 0 Cobalamin adenosyltransferase Apolipoprotein PF01442.13 KFO95422.1 - 0.087 12.3 36.2 3.5 7.0 13.1 3.8 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain CCD PF07860.6 KFO95422.1 - 0.093 12.2 1.9 13 5.2 0.0 3.2 3 1 0 3 3 3 0 WisP family C-Terminal Region DUF1664 PF07889.7 KFO95422.1 - 0.11 12.2 42.8 0.48 10.2 0.6 7.1 1 1 7 8 8 7 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 KFO95422.1 - 0.12 12.3 0.2 0.12 12.3 0.1 6.9 6 3 3 9 9 7 0 bZIP transcription factor DUF3584 PF12128.3 KFO95422.1 - 0.48 7.6 40.0 0.99 6.6 13.9 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3584) Laminin_I PF06008.9 KFO95422.1 - 0.66 9.2 43.4 0.13 11.5 3.8 5.2 1 1 4 5 5 5 0 Laminin Domain I HycH PF07450.6 KFO95422.1 - 0.75 9.8 7.7 0.41 10.7 0.6 3.6 2 2 0 3 3 3 0 Formate hydrogenlyase maturation protein HycH DUF4200 PF13863.1 KFO95422.1 - 0.81 9.6 45.2 3 7.8 0.1 5.8 2 1 4 6 6 6 0 Domain of unknown function (DUF4200) APG6 PF04111.7 KFO95422.1 - 0.85 8.6 46.5 0.085 11.8 8.4 4.1 1 1 3 4 4 4 0 Autophagy protein Apg6 Spc7 PF08317.6 KFO95422.1 - 1.2 7.7 54.5 0.22 10.1 0.2 4.7 1 1 4 5 5 5 0 Spc7 kinetochore protein NAAA-beta PF15508.1 KFO95422.1 - 1.3 9.4 7.7 50 4.3 0.3 5.1 2 2 3 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3349 PF11829.3 KFO95422.1 - 2.3 8.7 5.6 5.2 7.5 0.0 3.5 3 1 1 4 4 3 0 Protein of unknown function (DUF3349) Laminin_II PF06009.7 KFO95422.1 - 2.6 7.7 42.2 0.29 10.8 1.0 5.5 1 1 3 5 5 5 0 Laminin Domain II ADIP PF11559.3 KFO95422.1 - 4.3 7.2 46.8 0.33 10.8 3.6 5.8 1 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding Acetyltransf_11 PF13720.1 KFO95422.1 - 4.8 7.4 11.1 9.8 6.4 0.1 5.0 4 2 2 6 6 6 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Cast PF10174.4 KFO95422.1 - 4.9 5.0 47.1 2 6.3 4.2 3.2 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone DUF745 PF05335.8 KFO95422.1 - 5.9 6.3 33.2 1.7 8.1 2.9 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF745) DUF4164 PF13747.1 KFO95422.1 - 7.5 6.7 34.3 6.9 6.8 0.1 7.1 3 2 5 8 8 8 0 Domain of unknown function (DUF4164) Fez1 PF06818.10 KFO95422.1 - 8 6.4 36.7 1.5 8.8 6.8 4.2 1 1 3 4 4 4 0 Fez1 Pkinase PF00069.20 KFO95423.1 - 3.6e-71 239.3 0.1 5.6e-71 238.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95423.1 - 1.9e-38 132.0 0.0 2.9e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO95423.1 - 3.8e-06 26.0 0.3 7.7e-06 25.1 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFO95423.1 - 9.3e-06 24.7 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFO95423.1 - 2.7e-05 23.5 1.0 4.7e-05 22.8 0.7 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KFO95423.1 - 0.041 12.4 0.9 0.063 11.8 0.6 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PID PF00640.18 KFO95424.1 - 3.5e-08 33.5 0.2 9.6e-08 32.1 0.1 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.24 KFO95424.1 - 8.2e-08 32.3 0.0 5.1e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 PH domain PTB PF08416.8 KFO95424.1 - 6.9e-06 25.9 0.1 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine-binding domain DUF3263 PF11662.3 KFO95424.1 - 0.0045 16.4 0.2 0.023 14.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3263) PH_9 PF15410.1 KFO95424.1 - 0.0046 17.1 0.0 0.018 15.1 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain WASH-7_N PF14745.1 KFO95425.1 - 1.2e-212 707.1 22.1 1.2e-212 707.1 15.3 2.0 3 0 0 3 3 3 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.1 KFO95425.1 - 1.1e-169 563.8 10.1 1.1e-169 563.8 7.0 2.3 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_C PF14746.1 KFO95425.1 - 2.1e-74 248.7 3.2 2.1e-74 248.7 2.2 2.7 3 0 0 3 3 3 1 WASH complex subunit 7, C-terminal DUF4598 PF15370.1 KFO95426.1 - 1.4e-11 44.6 3.4 2.1e-11 44.1 2.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) Sigma70_r1_1 PF03979.9 KFO95426.1 - 0.00067 19.5 6.8 0.0011 18.8 4.7 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 Bd3614_N PF14442.1 KFO95426.1 - 0.0019 18.1 0.8 0.0024 17.8 0.5 1.1 1 0 0 1 1 1 1 Bd3614-like deaminase N-terminal MgtE PF01769.11 KFO95427.1 - 2.7e-42 144.2 14.6 5.1e-27 94.8 2.9 3.2 4 0 0 4 4 4 2 Divalent cation transporter Sulfotransfer_2 PF03567.9 KFO95428.1 - 3.1e-69 233.4 8.3 3.9e-69 233.1 5.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF2115 PF09888.4 KFO95428.1 - 0.028 14.5 1.3 0.056 13.5 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Pyr_redox_2 PF07992.9 KFO95429.1 - 1.1e-30 107.0 0.0 1.3e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFO95429.1 - 1.6e-26 92.4 0.0 6.6e-26 90.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFO95429.1 - 3.1e-15 56.3 0.3 8.1e-15 54.9 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFO95429.1 - 5.8e-07 29.7 0.0 9.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CBFD_NFYB_HMF PF00808.18 KFO95430.1 - 7.8e-29 99.5 0.4 1.2e-28 98.9 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFO95430.1 - 1.6e-06 28.0 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KFO95430.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KFO95430.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 KFO95430.1 - 0.097 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Kelch_3 PF13415.1 KFO95431.1 - 1.3e-34 117.5 8.6 3.6e-10 39.7 0.0 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO95431.1 - 1.3e-33 114.3 5.0 1.1e-07 31.6 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 KFO95431.1 - 9.8e-28 95.6 2.2 1.4e-07 31.1 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KFO95431.1 - 1.7e-21 75.4 5.8 9.3e-05 21.8 0.1 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFO95431.1 - 1.3e-18 66.2 9.9 0.0031 17.6 0.0 5.7 4 2 1 5 5 5 5 Kelch motif Kelch_2 PF07646.10 KFO95431.1 - 1.8e-17 62.3 6.1 0.00096 18.8 0.0 5.8 5 0 0 5 5 5 5 Kelch motif fn3 PF00041.16 KFO95431.1 - 2.3e-11 43.6 0.7 0.01 15.9 0.0 4.3 4 0 0 4 4 4 3 Fibronectin type III domain Glyco_transf_8 PF01501.15 KFO95432.1 - 1.5e-46 158.7 0.0 1.9e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 UDG PF03167.14 KFO95433.1 - 1e-16 60.7 0.0 1.7e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GAGA_bind PF06217.7 KFO95433.1 - 0.0041 17.1 4.0 0.0075 16.2 2.8 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family DUF4516 PF14990.1 KFO95434.1 - 3.2e-24 84.2 0.5 3.8e-24 83.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) HSP90 PF00183.13 KFO95435.1 - 1.1e-235 783.0 32.8 1.1e-235 783.0 22.7 1.6 2 0 0 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.1 KFO95435.1 - 2.1e-12 46.8 0.6 2.1e-12 46.8 0.4 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFO95435.1 - 6.5e-12 45.1 0.3 1.3e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MH1 PF03165.11 KFO95435.1 - 0.21 11.6 1.9 0.71 9.8 0.0 2.8 3 0 0 3 3 3 0 MH1 domain 5_nucleotid PF05761.9 KFO95436.1 - 7.9e-164 545.4 8.4 9e-164 545.2 5.8 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 KFO95436.1 - 0.00031 21.0 1.9 0.035 14.3 0.3 3.6 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Condensin2nSMC PF12422.3 KFO95436.1 - 0.063 13.0 0.1 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Biopterin_H PF00351.16 KFO95438.1 - 2e-186 618.5 0.2 3.2e-186 617.7 0.1 1.3 2 0 0 2 2 2 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 KFO95438.1 - 2.4e-07 30.0 0.0 5.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 KFO95438.1 - 0.0021 18.3 0.2 0.023 15.0 0.0 2.2 2 0 0 2 2 2 1 ACT domain Biopterin_H PF00351.16 KFO95439.1 - 2.4e-173 575.5 1.6 2.8e-173 575.2 1.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Insulin PF00049.13 KFO95440.1 - 3.2e-14 53.4 8.5 3.2e-12 47.0 4.1 2.5 2 1 0 2 2 2 1 Insulin/IGF/Relaxin family Ins_beta PF03488.9 KFO95440.1 - 0.15 11.8 2.0 5.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Pro-MCH PF05824.7 KFO95441.1 - 2.8e-31 106.8 0.0 3.9e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 Pro-melanin-concentrating hormone (Pro-MCH) UvrD_C PF13361.1 KFO95442.1 - 4.4e-06 26.4 0.0 7.9e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF1285 PF06938.6 KFO95442.1 - 0.11 12.5 0.0 0.3 11.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1285) WD40 PF00400.27 KFO95443.1 - 6.3e-17 60.7 1.8 2.6e-09 36.5 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF2360 PF10152.4 KFO95444.1 - 2e-48 164.4 1.0 2.4e-48 164.1 0.7 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Frag1 PF10277.4 KFO95445.1 - 2.8e-49 167.5 17.2 3.1e-49 167.3 11.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF360 PF04020.8 KFO95445.1 - 0.19 12.0 4.9 0.097 13.0 0.8 2.5 1 1 2 3 3 3 0 Membrane protein of unknown function Notch PF00066.12 KFO95446.1 - 6.5e-20 71.1 32.5 2.7e-11 43.5 9.4 2.4 2 0 0 2 2 2 2 LNR domain DMAP_binding PF06464.6 KFO95446.1 - 9e-11 42.3 0.6 3.1e-10 40.6 0.4 2.0 1 0 0 1 1 1 1 DMAP1-binding Domain DUF3184 PF11380.3 KFO95446.1 - 2.5e-07 29.0 4.5 0.0011 17.0 0.2 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3184) EF-hand_1 PF00036.27 KFO95446.1 - 0.015 14.5 0.0 0.041 13.1 0.0 1.8 1 0 0 1 1 1 0 EF hand Vanabin-2 PF11437.3 KFO95446.1 - 1.8 8.5 6.9 16 5.5 1.0 2.6 2 0 0 2 2 2 0 Vanadium-binding protein 2 Cor1 PF04803.7 KFO95447.1 - 2e-58 195.7 26.6 2e-58 195.7 18.4 1.5 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region UPF0020 PF01170.13 KFO95447.1 - 1.2 8.6 6.2 4.9 6.6 0.3 2.5 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Exonuc_VII_L PF02601.10 KFO95447.1 - 4.7 6.2 15.5 8.5 5.4 10.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med7 PF05983.6 KFO95447.1 - 8.3 6.1 16.5 0.48 10.1 6.8 2.1 1 1 1 2 2 2 0 MED7 protein Vac_Fusion PF02346.11 KFO95447.1 - 8.5 5.8 7.3 2.3 7.7 1.3 2.8 2 1 1 3 3 3 0 Chordopoxvirus fusion protein CDP-OH_P_transf PF01066.16 KFO95448.1 - 1.2e-13 51.1 10.9 1.3e-12 47.8 7.5 2.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Ank_2 PF12796.2 KFO95449.1 - 7e-72 237.8 13.8 1e-21 77.0 0.1 5.0 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 KFO95449.1 - 5e-68 229.0 0.0 8.7e-68 228.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.25 KFO95449.1 - 1.1e-63 207.9 8.8 8.1e-09 34.8 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KFO95449.1 - 2e-48 161.9 6.4 1.2e-10 41.5 0.0 7.2 2 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO95449.1 - 1.8e-47 158.2 14.5 2.4e-09 37.1 0.1 7.3 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO95449.1 - 5.1e-44 143.8 8.0 8.2e-06 25.5 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Pkinase_Tyr PF07714.12 KFO95449.1 - 5.3e-34 117.4 0.0 1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO95449.1 - 4.2e-06 25.9 0.0 1.8e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFO95449.1 - 8.8e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family G-alpha PF00503.15 KFO95449.1 - 0.011 14.4 0.2 0.02 13.6 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Choline_kinase PF01633.15 KFO95449.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA_29 PF13555.1 KFO95449.1 - 0.037 13.5 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glycos_trans_3N PF02885.12 KFO95449.1 - 0.037 13.5 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 1 0 Glycosyl transferase family, helical bundle domain AAA_23 PF13476.1 KFO95449.1 - 0.053 13.8 0.1 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFO95449.1 - 0.081 13.2 0.1 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter APH PF01636.18 KFO95449.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_17 PF13207.1 KFO95449.1 - 0.97 10.2 3.3 2.2 9.1 0.2 3.1 4 0 0 4 4 3 0 AAA domain Death PF00531.17 KFO95450.1 - 7.9e-16 57.6 0.1 6.4e-15 54.6 0.0 2.6 3 0 0 3 3 3 1 Death domain Peptidase_C1 PF00112.18 KFO95451.1 - 5.9e-90 300.9 3.0 8.9e-90 300.3 2.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KFO95451.1 - 3.2e-14 52.9 1.9 6.5e-14 51.9 1.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KFO95451.1 - 4.1e-06 25.5 3.0 0.00027 19.5 0.8 2.1 2 0 0 2 2 2 2 Peptidase C1-like family FBPase PF00316.15 KFO95452.1 - 1.3e-135 451.3 0.0 1.5e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KFO95452.1 - 4.9e-06 26.0 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Inositol monophosphatase family DUF159 PF02586.9 KFO95452.1 - 0.19 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, COG2135 Peptidase_M1 PF01433.15 KFO95453.1 - 5.4e-24 85.0 0.0 1.1e-11 44.5 0.0 2.6 2 1 1 3 3 3 2 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFO95453.1 - 1.8e-15 56.7 0.5 4.5e-15 55.5 0.4 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFO95453.1 - 5.2e-11 42.6 0.1 1.5e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily DLH PF01738.13 KFO95453.1 - 0.027 13.7 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Fanconi_C PF02106.10 KFO95454.1 - 1.8e-256 852.0 22.2 2e-256 851.8 15.4 1.0 1 0 0 1 1 1 1 Fanconi anaemia group C protein EF-hand_2 PF09068.6 KFO95454.1 - 0.0033 17.5 2.9 3.4 7.7 0.0 3.3 2 1 0 2 2 2 2 EF hand Patched PF02460.13 KFO95455.1 - 4e-74 249.9 19.8 1.5e-43 148.8 0.9 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KFO95455.1 - 2.8e-46 156.7 4.9 2.8e-46 156.7 3.4 2.8 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MENTAL PF10457.4 KFO95455.1 - 1.8 8.1 7.1 4.1 6.9 0.2 2.4 2 0 0 2 2 2 0 Cholesterol-capturing domain SNF2_N PF00176.18 KFO95456.1 - 1.8e-58 197.6 0.6 2.8e-58 197.1 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFO95456.1 - 4.5e-15 55.2 0.4 1.8e-14 53.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFO95456.1 - 1.1e-08 34.7 0.0 2.8e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KFO95456.1 - 1.2e-07 30.8 0.3 5.8e-07 28.6 0.2 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFO95456.1 - 1.2e-07 31.6 0.1 3.5e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SMN PF06003.7 KFO95456.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) VIGSSK PF14773.1 KFO95457.1 - 7.5e-09 35.3 0.1 2.6e-08 33.6 0.1 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Acyl-thio_N PF12590.3 KFO95457.1 - 0.3 11.5 2.6 8.3 6.8 0.1 2.4 1 1 1 2 2 2 0 Acyl-ATP thioesterase NST1 PF13945.1 KFO95457.1 - 4.5 7.2 13.6 0.1 12.6 0.3 2.9 2 1 0 3 3 3 0 Salt tolerance down-regulator adh_short PF00106.20 KFO95458.1 - 2.6e-22 79.4 0.0 3.2e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFO95458.1 - 1.8e-05 24.6 0.0 2.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFO95458.1 - 0.00029 20.5 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KFO95458.1 - 0.0059 16.6 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KFO95458.1 - 0.033 14.2 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF543 PF04418.7 KFO95458.1 - 0.067 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) 3HCDH_N PF02737.13 KFO95458.1 - 0.11 12.1 0.2 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KFO95458.1 - 0.11 11.8 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 KFO95458.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase TPT PF03151.11 KFO95459.1 - 6.7e-11 42.0 8.3 6.7e-11 42.0 5.8 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFO95459.1 - 2.9e-05 23.1 13.5 4.2e-05 22.6 9.4 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KFO95459.1 - 1 9.5 17.9 2.9 8.0 2.0 2.5 2 1 0 2 2 2 0 Multidrug resistance efflux transporter zf-H2C2_2 PF13465.1 KFO95460.1 - 4.5e-16 58.2 7.8 1e-07 31.8 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO95460.1 - 1.1e-09 38.0 12.1 5.9e-05 23.1 0.4 3.3 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO95460.1 - 5.5e-07 29.4 13.3 0.00019 21.5 0.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO95460.1 - 7.3e-06 25.6 0.7 0.00011 21.9 0.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 KFO95460.1 - 0.00013 21.9 0.7 0.00062 19.8 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO95460.1 - 0.00014 21.9 0.3 0.0018 18.3 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Nucleo_P87 PF07267.6 KFO95460.1 - 0.073 11.7 1.7 0.079 11.6 1.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HABP4_PAI-RBP1 PF04774.10 KFO95461.1 - 2.5e-11 44.0 7.8 2.5e-11 44.0 5.4 3.1 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family DSPn PF14671.1 KFO95462.1 - 4.9e-56 188.6 3.2 9e-55 184.5 1.2 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KFO95462.1 - 1.2e-15 57.2 0.0 2.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO95462.1 - 2.8e-06 26.8 0.1 7.1e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFO95462.1 - 9.8e-06 25.6 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFO95462.1 - 0.00076 19.7 0.1 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KFO95462.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family AhpC-TSA_2 PF13911.1 KFO95463.1 - 2.6e-19 69.2 0.0 3e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KFO95463.1 - 0.035 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 KFO95463.1 - 0.04 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF3350 PF11830.3 KFO95464.1 - 0.019 14.9 1.2 0.019 14.9 0.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3350) DUF2407_C PF13373.1 KFO95464.1 - 0.057 13.3 2.2 0.062 13.2 1.6 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain MIT PF04212.13 KFO95464.1 - 0.19 11.6 2.1 0.23 11.3 1.4 1.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain CFC PF09443.5 KFO95465.1 - 2.2e-14 52.7 9.8 2.2e-14 52.7 6.8 2.6 3 0 0 3 3 3 1 Cripto_Frl-1_Cryptic (CFC) EGF PF00008.22 KFO95465.1 - 0.021 14.7 8.0 0.021 14.7 5.5 2.2 3 0 0 3 3 3 0 EGF-like domain LRR_4 PF12799.2 KFO95466.1 - 7.3e-25 86.1 21.0 1.8e-08 33.8 1.8 5.5 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO95466.1 - 2.8e-24 84.6 13.0 1.1e-08 34.7 2.6 4.3 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KFO95466.1 - 5.4e-17 59.2 21.1 0.0016 18.2 0.2 7.8 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 KFO95466.1 - 7.7e-11 40.3 16.9 0.24 11.7 0.0 7.4 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 KFO95466.1 - 3e-08 32.8 12.4 0.31 11.2 0.1 5.8 5 1 0 5 5 5 3 Leucine Rich repeat F5_F8_type_C PF00754.20 KFO95467.1 - 9.1e-29 99.9 2.1 1.1e-28 99.6 0.4 1.7 2 0 0 2 2 2 1 F5/8 type C domain Laminin_G_2 PF02210.19 KFO95467.1 - 8e-25 87.3 0.4 1.3e-24 86.6 0.3 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFO95467.1 - 3.3e-13 49.7 0.1 5.6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain DUF1554 PF07588.6 KFO95467.1 - 0.054 12.9 0.7 0.13 11.7 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1554) Lipase_GDSL_2 PF13472.1 KFO95468.1 - 1.8e-05 24.9 0.0 3.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 KFO95469.1 - 2.5e-35 121.8 38.9 2.3e-34 118.7 26.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Spin-Ssty PF02513.12 KFO95470.1 - 1.6e-77 254.8 6.7 1.2e-27 95.2 0.1 3.2 3 0 0 3 3 3 3 Spin/Ssty Family Thioredoxin_8 PF13905.1 KFO95471.1 - 1.4e-15 57.1 0.0 2.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 KFO95471.1 - 3.4e-08 33.1 1.9 0.00047 19.7 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KFO95471.1 - 1e-05 25.7 0.1 1.4e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KFO95471.1 - 0.0005 19.7 0.1 0.0012 18.5 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFO95471.1 - 0.00065 19.2 0.1 0.00093 18.7 0.1 1.2 1 1 0 1 1 1 1 Redoxin TrbC_Ftype PF09673.5 KFO95471.1 - 0.023 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein NADH_4Fe-4S PF10589.4 KFO95471.1 - 0.039 13.0 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Eco57I PF07669.6 KFO95471.1 - 0.069 13.5 0.1 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Eco57I restriction-modification methylase KaiB PF07689.7 KFO95471.1 - 0.069 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 KaiB domain Thioredoxin_3 PF13192.1 KFO95471.1 - 0.17 11.7 0.8 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Thioredoxin domain CKS PF01111.14 KFO95472.1 - 3.7e-40 135.5 2.4 4.2e-40 135.4 1.6 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_L7Ae PF01248.21 KFO95473.1 - 1.3e-21 75.8 0.3 3e-21 74.7 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family C1-set PF07654.10 KFO95474.1 - 0.14 12.1 0.6 0.24 11.4 0.2 1.5 1 1 0 1 1 1 0 Immunoglobulin C1-set domain Sema PF01403.14 KFO95475.1 - 6.4e-144 479.6 0.2 8.3e-144 479.3 0.1 1.1 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFO95475.1 - 5e-09 36.1 3.0 1.6e-08 34.5 2.1 1.9 1 0 0 1 1 1 1 Plexin repeat Ig_2 PF13895.1 KFO95475.1 - 0.00024 21.1 0.0 0.00064 19.7 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFO95475.1 - 0.00073 19.3 0.5 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 KFO95475.1 - 0.0037 17.3 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFO95475.1 - 0.0057 16.5 0.2 0.1 12.4 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ras PF00071.17 KFO95476.1 - 2.3e-50 170.1 0.1 2.8e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95476.1 - 2.1e-23 83.0 0.2 3.9e-23 82.1 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFO95476.1 - 5e-07 29.1 0.0 7.2e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family ArgK PF03308.11 KFO95476.1 - 0.00046 19.0 1.0 0.065 12.0 0.3 2.1 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 KFO95476.1 - 0.0054 16.6 0.0 0.0081 16.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFO95476.1 - 0.02 15.0 0.1 0.18 11.9 0.1 2.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFO95476.1 - 0.024 14.3 0.7 0.056 13.1 0.5 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_32 PF13654.1 KFO95476.1 - 0.026 13.1 2.2 0.98 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFO95476.1 - 0.038 13.1 1.0 0.096 11.8 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KFO95476.1 - 0.064 12.8 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2408 PF10303.4 KFO95476.1 - 0.23 11.5 5.3 4.4 7.4 3.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2408) Pkinase_Tyr PF07714.12 KFO95477.1 - 5e-85 284.7 0.3 7e-85 284.2 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO95477.1 - 7.6e-47 159.6 0.1 1.1e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFO95477.1 - 7.9e-40 134.5 0.2 5.8e-21 74.0 0.1 2.4 2 0 0 2 2 2 2 SH2 domain Kdo PF06293.9 KFO95477.1 - 0.0016 17.5 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFO95477.1 - 0.091 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KFO95477.1 - 0.13 11.6 0.4 0.22 10.8 0.3 1.3 1 0 0 1 1 1 0 RIO1 family p25-alpha PF05517.7 KFO95478.1 - 3.5e-54 183.2 3.3 3.9e-54 183.0 2.3 1.0 1 0 0 1 1 1 1 p25-alpha RNA_pol_Rpb1_5 PF04998.12 KFO95478.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 EF-hand_1 PF00036.27 KFO95478.1 - 0.76 9.2 3.4 2.4 7.6 0.0 3.2 4 0 0 4 4 4 0 EF hand ECH PF00378.15 KFO95479.1 - 1.2e-60 204.6 2.2 1.4e-60 204.4 1.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3798 PF12683.2 KFO95479.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Vert_IL3-reg_TF PF06529.6 KFO95480.1 - 2.2e-206 684.3 19.4 2.9e-206 683.9 13.4 1.2 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor bZIP_2 PF07716.10 KFO95480.1 - 1.6e-14 53.4 9.3 1.6e-14 53.4 6.4 2.8 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 KFO95480.1 - 3e-05 23.8 6.5 3e-05 23.8 4.5 3.2 3 0 0 3 3 3 1 bZIP transcription factor Pkinase_Tyr PF07714.12 KFO95481.1 - 3.6e-87 291.7 0.0 4.8e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO95481.1 - 4.5e-41 140.7 0.0 6.4e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kringle PF00051.13 KFO95481.1 - 4.5e-25 87.5 1.7 2.4e-24 85.2 1.1 2.3 2 0 0 2 2 2 1 Kringle domain Fz PF01392.17 KFO95481.1 - 8.3e-24 84.1 4.3 3.1e-23 82.3 3.0 2.1 1 0 0 1 1 1 1 Fz domain I-set PF07679.11 KFO95481.1 - 4.8e-18 64.7 0.0 9.2e-18 63.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO95481.1 - 3.4e-09 36.6 1.4 1.5e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFO95481.1 - 4.8e-07 29.6 0.2 4e-06 26.7 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFO95481.1 - 7.3e-07 29.2 0.0 2.1e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO95481.1 - 2.1e-06 28.1 0.0 8.1e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain TMEM154 PF15102.1 KFO95481.1 - 0.0039 16.9 0.1 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 TMEM154 protein family DUF2149 PF09919.4 KFO95481.1 - 0.083 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Aminotran_1_2 PF00155.16 KFO95482.1 - 1.6e-41 142.4 0.0 1.9e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PAD PF03068.10 KFO95482.1 - 0.0022 16.4 0.0 0.003 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Cys_Met_Meta_PP PF01053.15 KFO95482.1 - 0.081 11.1 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PBD PF00786.23 KFO95483.1 - 1.8e-05 25.0 1.1 2.3e-05 24.6 0.7 1.4 1 1 0 1 1 1 1 P21-Rho-binding domain Complex1_LYR PF05347.10 KFO95484.1 - 3.4e-09 36.3 0.2 4.9e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFO95484.1 - 6e-09 35.9 0.1 7.5e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.6 KFO95484.1 - 0.014 15.1 0.1 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Bt_P21 PF05560.6 KFO95484.1 - 0.046 13.1 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein pRN1_helical PF13010.1 KFO95484.1 - 0.056 13.0 0.6 0.069 12.7 0.4 1.2 1 0 0 1 1 1 0 Primase helical domain DUF2570 PF10828.3 KFO95484.1 - 0.061 12.9 0.7 0.077 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SBDS PF01172.13 KFO95484.1 - 0.093 12.5 0.6 0.14 11.9 0.4 1.4 1 1 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein HIT PF01230.18 KFO95485.1 - 7e-25 87.4 0.0 7.7e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFO95485.1 - 7.9e-18 64.7 0.0 8.9e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Yae1_N PF09811.4 KFO95486.1 - 1.7e-11 43.4 38.0 15 5.2 23.4 4.2 1 1 1 2 2 2 2 Essential protein Yae1, N terminal wnt PF00110.14 KFO95487.1 - 1e-125 419.0 24.1 1.2e-125 418.8 16.7 1.0 1 0 0 1 1 1 1 wnt family DSPc PF00782.15 KFO95488.1 - 2.2e-12 46.7 0.0 6.4e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO95488.1 - 4.3e-09 36.0 0.0 8.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KFO95488.1 - 0.00044 19.7 0.0 0.0013 18.1 0.0 1.7 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 KFO95488.1 - 0.0026 18.0 0.0 0.06 13.5 0.1 2.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Glyco_hydro_88 PF07470.8 KFO95488.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Homeobox PF00046.24 KFO95489.1 - 2.1e-21 75.2 2.1 2.1e-21 75.2 1.4 1.5 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 KFO95489.1 - 0.034 13.1 0.4 0.058 12.4 0.3 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez JmjC PF02373.17 KFO95490.1 - 2.3e-12 47.1 0.3 2.3e-12 47.1 0.2 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KFO95490.1 - 2.5e-08 33.7 1.8 7.8e-08 32.1 0.0 2.5 2 0 0 2 2 2 1 Cupin-like domain Ninjurin PF04923.7 KFO95493.1 - 5.7e-37 125.6 4.0 6.4e-37 125.4 2.8 1.0 1 0 0 1 1 1 1 Ninjurin CARD PF00619.16 KFO95494.1 - 3.4e-08 33.2 0.1 5.9e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain YWFCY PF14293.1 KFO95494.1 - 0.1 12.4 0.3 17 5.3 0.0 2.6 2 0 0 2 2 2 0 YWFCY protein Sushi PF00084.15 KFO95495.1 - 0.00023 21.4 0.1 0.00039 20.7 0.1 1.4 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Shisa PF13908.1 KFO95495.1 - 0.0024 18.0 0.2 0.0029 17.8 0.2 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.9 KFO95495.1 - 0.0048 16.5 0.1 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 IncA protein REJ PF02010.10 KFO95495.1 - 0.13 10.5 0.1 0.25 9.5 0.0 1.3 1 0 0 1 1 1 0 REJ domain EphA2_TM PF14575.1 KFO95495.1 - 0.14 12.5 0.2 0.21 12.0 0.1 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RhoGEF PF00621.15 KFO95496.1 - 1.1e-47 162.2 0.6 1.1e-47 162.2 0.4 2.0 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.24 KFO95496.1 - 1.1e-18 67.3 0.9 1.7e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 PH domain FYVE PF01363.16 KFO95496.1 - 1.5e-14 53.6 14.6 9.8e-14 51.0 10.2 2.3 2 0 0 2 2 2 1 FYVE zinc finger PH_11 PF15413.1 KFO95496.1 - 0.0043 17.3 2.4 0.018 15.3 0.0 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 KFO95496.1 - 0.039 14.1 2.2 6.8 6.8 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.2 KFO95496.1 - 0.051 13.4 0.2 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology FYVE_2 PF02318.11 KFO95496.1 - 7.2 6.5 24.4 0.088 12.7 9.8 2.9 3 0 0 3 3 3 0 FYVE-type zinc finger DZR PF12773.2 KFO95496.1 - 8.5 6.2 18.5 68 3.3 2.6 2.7 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H PF13771.1 KFO95497.1 - 2.5e-14 53.1 2.5 2.5e-14 53.1 1.7 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFO95497.1 - 6.6e-06 26.0 6.3 6.6e-06 26.0 4.4 3.3 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-SNAP50_C PF12251.3 KFO95497.1 - 0.99 8.7 12.7 0.086 12.2 2.5 2.3 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal tRNA-synt_1 PF00133.17 KFO95498.1 - 4.5e-228 758.1 0.0 1.3e-227 756.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFO95498.1 - 1e-26 93.5 0.4 2.7e-26 92.1 0.1 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFO95498.1 - 5e-17 61.6 0.9 6.3e-05 21.8 0.1 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KFO95498.1 - 0.0083 15.2 0.0 0.03 13.4 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain E1-E2_ATPase PF00122.15 KFO95499.1 - 8.4e-55 185.2 1.1 1.8e-54 184.2 0.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFO95499.1 - 4.6e-44 150.1 6.1 1.4e-43 148.5 1.9 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.3 KFO95499.1 - 7.2e-30 103.1 0.0 1.7e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.21 KFO95499.1 - 2.6e-25 90.0 0.0 9.2e-25 88.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFO95499.1 - 7.8e-16 57.8 0.0 1.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFO95499.1 - 8.6e-16 57.1 0.0 5e-15 54.7 0.0 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFO95499.1 - 2.4e-14 53.9 0.0 5e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFO95499.1 - 1.1e-07 31.6 2.1 1.5e-05 24.6 0.3 2.6 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase SNF PF00209.13 KFO95500.1 - 6.1e-247 820.2 39.0 7e-247 820.0 27.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.13 KFO95501.1 - 3.7e-233 774.7 41.1 4.3e-233 774.5 28.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 7tm_1 PF00001.16 KFO95502.1 - 1.5e-70 237.2 2.5 2.4e-70 236.6 1.7 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO95502.1 - 8.4e-09 34.9 13.5 3.1e-05 23.2 3.8 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO95502.1 - 0.11 11.5 15.4 0.0058 15.7 6.1 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx ThiF PF00899.16 KFO95503.1 - 3.2e-34 117.6 0.0 4.9e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KFO95503.1 - 0.0018 18.3 0.2 0.0074 16.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase VGLL4 PF15245.1 KFO95504.1 - 8.3e-96 319.9 4.0 8.3e-96 319.9 2.8 1.9 2 1 1 3 3 3 1 Transcription cofactor vestigial-like protein 4 Vg_Tdu PF07545.9 KFO95504.1 - 0.014 14.8 0.0 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Vestigial/Tondu family DUF3868 PF12984.2 KFO95504.1 - 0.024 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Mmp37 PF09139.6 KFO95505.1 - 1.9e-93 313.1 0.1 2.1e-93 312.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Synapsin_C PF02750.9 KFO95506.1 - 5e-130 430.6 0.6 6.3e-130 430.3 0.4 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.11 KFO95506.1 - 7e-16 58.2 0.0 1.5e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Synapsin, N-terminal domain RimK PF08443.6 KFO95506.1 - 1.4e-05 24.6 0.0 6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain PAT1 PF09770.4 KFO95506.1 - 4 5.5 46.2 5.5 5.1 32.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TIMP PF00965.12 KFO95507.1 - 3.8e-60 202.5 3.7 4.2e-60 202.4 2.5 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 KFO95507.1 - 0.033 13.7 0.3 0.045 13.3 0.1 1.4 1 1 0 1 1 1 0 UNC-6/NTR/C345C module CH PF00307.26 KFO95507.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.4 1 1 0 1 1 1 0 Calponin homology (CH) domain PPARgamma_N PF12577.3 KFO95508.1 - 2.9e-34 117.2 1.3 6.4e-34 116.1 0.9 1.6 1 0 0 1 1 1 1 PPAR gamma N-terminal region Hormone_recep PF00104.25 KFO95508.1 - 1.6e-30 105.7 2.0 2e-30 105.4 0.7 1.6 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO95508.1 - 1.3e-27 95.8 15.0 2.5e-27 94.9 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) tRNA_int_endo_N PF02778.9 KFO95509.1 - 1.7e-19 69.1 0.4 5.1e-14 51.5 0.1 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain tRNA_int_endo PF01974.12 KFO95509.1 - 4.1e-19 68.1 0.0 8.9e-19 67.0 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Menin PF05053.8 KFO95509.1 - 0.37 8.9 2.7 0.48 8.5 1.9 1.1 1 0 0 1 1 1 0 Menin zf-CCCH PF00642.19 KFO95510.1 - 3.3e-21 74.4 30.4 1.4e-06 27.8 2.3 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFO95510.1 - 1.7e-06 27.7 24.8 0.02 14.8 0.7 5.5 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type zf-RING_2 PF13639.1 KFO95510.1 - 1.1e-05 25.2 8.7 1.1e-05 25.2 6.0 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KFO95510.1 - 4.4e-05 23.0 10.1 4.4e-05 23.0 7.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO95510.1 - 0.0007 19.2 8.8 0.0007 19.2 6.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFO95510.1 - 0.0018 18.1 9.5 0.003 17.3 4.2 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFO95510.1 - 0.0057 16.6 8.8 0.0057 16.6 6.1 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFO95510.1 - 1.7 8.8 20.4 0.15 12.1 10.0 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger Pkinase_Tyr PF07714.12 KFO95511.1 - 3.5e-64 216.3 0.0 4.6e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO95511.1 - 2.7e-61 207.0 0.0 3.9e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.10 KFO95511.1 - 8.6e-30 102.3 0.3 2.3e-29 100.9 0.1 1.8 2 0 0 2 2 2 1 Raf-like Ras-binding domain C1_1 PF00130.17 KFO95511.1 - 7.2e-12 44.8 8.3 1.4e-11 43.8 5.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KFO95511.1 - 6.9e-08 31.7 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.6 KFO95511.1 - 0.036 14.0 6.6 0.1 12.6 4.6 1.8 1 0 0 1 1 1 0 RING-like domain APH PF01636.18 KFO95511.1 - 0.16 11.6 0.0 0.81 9.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_3 PF07649.7 KFO95511.1 - 0.55 10.3 7.0 1 9.4 4.9 1.5 1 0 0 1 1 1 0 C1-like domain zf-AN1 PF01428.11 KFO95511.1 - 5.3 6.9 10.5 5.1 7.0 5.6 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-CCHC PF00098.18 KFO95513.1 - 1e-52 173.6 62.2 5.3e-08 32.4 2.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KFO95513.1 - 2.7e-14 52.5 52.0 0.0016 18.0 0.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.1 KFO95513.1 - 3.5e-09 35.9 49.1 0.0036 16.7 1.8 6.8 4 1 3 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 KFO95513.1 - 5.1e-08 32.5 48.1 0.0023 17.6 0.2 7.1 2 1 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 KFO95513.1 - 0.046 13.3 47.6 0.098 12.3 0.5 7.1 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 KFO95513.1 - 0.45 10.0 0.1 0.45 10.0 0.1 7.1 3 2 4 7 7 7 0 Zinc knuckle Isy1 PF06246.7 KFO95514.1 - 5e-70 235.8 7.5 5.8e-70 235.6 5.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Ebp2 PF05890.7 KFO95514.1 - 0.037 13.3 5.5 0.064 12.5 3.8 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Hydrolase_6 PF13344.1 KFO95515.1 - 2.2e-22 78.8 0.0 4.7e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFO95515.1 - 5e-05 22.9 0.0 0.0011 18.5 0.0 2.6 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFO95515.1 - 0.058 13.8 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase AviRa PF11599.3 KFO95515.1 - 0.13 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Ras PF00071.17 KFO95516.1 - 4.5e-36 123.6 0.1 5.5e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95516.1 - 5.4e-07 30.1 0.0 1.2e-06 29.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFO95516.1 - 2.2e-06 27.0 0.1 2.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO95516.1 - 0.045 13.1 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF2786 PF10979.3 KFO95516.1 - 0.074 12.7 0.2 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) SLAIN PF15301.1 KFO95517.1 - 1.3 8.1 5.3 8 5.5 0.1 2.9 1 1 2 3 3 3 0 SLAIN motif-containing family LMF1 PF06762.9 KFO95518.1 - 1.7e-142 474.8 1.5 2e-142 474.5 1.1 1.1 1 0 0 1 1 1 1 Lipase maturation factor DUF2797 PF10977.3 KFO95520.1 - 6.3 6.3 7.8 11 5.5 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) AAA PF00004.24 KFO95522.1 - 7.8e-14 52.0 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFO95522.1 - 5.3e-10 39.1 0.0 9.9e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFO95522.1 - 4.2e-08 32.5 0.0 6.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFO95522.1 - 6.4e-07 29.5 0.0 1.6e-05 25.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KFO95522.1 - 2.1e-06 26.7 0.0 8.3e-06 24.7 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KFO95522.1 - 2.4e-06 27.4 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFO95522.1 - 8e-06 26.6 0.1 3.1e-05 24.7 0.0 2.1 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 KFO95522.1 - 0.0001 22.2 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFO95522.1 - 0.00016 21.3 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFO95522.1 - 0.00021 21.3 0.0 0.047 13.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFO95522.1 - 0.00029 21.1 0.0 0.00066 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFO95522.1 - 0.0018 17.7 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KFO95522.1 - 0.0024 17.0 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 KFO95522.1 - 0.0032 17.5 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.7 KFO95522.1 - 0.0039 16.8 0.0 0.12 11.9 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_28 PF13521.1 KFO95522.1 - 0.0063 16.4 1.2 0.04 13.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 KFO95522.1 - 0.0074 15.7 0.2 0.034 13.5 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 KFO95522.1 - 0.0082 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KFO95522.1 - 0.0087 15.7 0.3 0.21 11.2 0.0 2.3 1 1 0 2 2 2 1 NTPase DUF258 PF03193.11 KFO95522.1 - 0.0094 15.1 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KFO95522.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.6 1 1 1 2 2 1 0 ABC transporter NB-ARC PF00931.17 KFO95522.1 - 0.016 14.1 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 KFO95522.1 - 0.023 13.4 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus NAD_binding_1 PF00175.16 KFO95522.1 - 0.028 14.9 0.0 0.77 10.3 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Viral_helicase1 PF01443.13 KFO95522.1 - 0.029 13.8 0.0 0.21 11.0 0.0 1.9 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 KFO95522.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFO95522.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 KFO95522.1 - 0.081 12.7 0.3 1.3 8.8 0.0 2.4 2 1 0 2 2 2 0 Shikimate kinase PseudoU_synth_2 PF00849.17 KFO95523.1 - 1.9e-25 89.5 0.0 2.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Corona_S1 PF01600.11 KFO95523.1 - 0.051 11.8 0.0 0.071 11.3 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein MYCBPAP PF14646.1 KFO95523.1 - 0.062 12.0 0.0 0.083 11.5 0.0 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family Mesothelin PF06060.7 KFO95525.1 - 4.1e-13 48.2 0.4 4.5e-13 48.1 0.3 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Mesothelin PF06060.7 KFO95526.1 - 2.3e-128 428.9 0.0 2.8e-128 428.6 0.0 1.0 1 0 0 1 1 1 1 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) DED PF01335.16 KFO95526.1 - 0.47 10.6 3.5 5.3 7.2 0.2 3.3 2 1 0 2 2 2 0 Death effector domain Fe_hyd_lg_C PF02906.9 KFO95528.1 - 1.4e-90 303.4 0.0 2e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 KFO95528.1 - 1.1e-10 41.3 0.2 3.8e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Iron hydrogenase small subunit PRTase_3 PF15610.1 KFO95528.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like Lactamase_B PF00753.22 KFO95529.1 - 3.2e-21 75.8 0.2 4.4e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFO95529.1 - 9.2e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFO95530.1 - 4.4e-27 95.0 0.4 5.8e-27 94.6 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFO95530.1 - 7.8e-05 22.2 0.1 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RecR PF02132.10 KFO95531.1 - 0.39 10.1 3.5 1.2 8.6 2.4 1.8 1 0 0 1 1 1 0 RecR protein Sulfotransfer_1 PF00685.22 KFO95532.1 - 7.5e-32 110.6 0.0 8.9e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFO95532.1 - 0.0087 15.7 0.0 0.036 13.7 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family SelR PF01641.13 KFO95533.1 - 4.6e-16 58.6 0.0 4.9e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 SelR domain Zn_ribbon_recom PF13408.1 KFO95533.1 - 0.0024 18.0 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain RRN7 PF11781.3 KFO95533.1 - 0.0082 15.6 1.8 0.14 11.6 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_2 PF13240.1 KFO95533.1 - 0.015 14.7 1.3 1.7 8.2 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 KFO95533.1 - 0.024 14.9 0.1 0.057 13.7 0.0 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.2 KFO95533.1 - 0.039 13.7 0.6 0.086 12.6 0.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 KFO95533.1 - 0.051 12.9 0.2 9.2 5.6 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding GFA PF04828.9 KFO95533.1 - 0.094 12.6 0.7 4.9 7.1 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TFIIS_C PF01096.13 KFO95533.1 - 0.094 12.3 1.2 3 7.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF983 PF06170.7 KFO95533.1 - 0.14 12.2 0.4 5.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DNA_RNApol_7kD PF03604.8 KFO95533.1 - 0.15 11.5 2.9 1.1 8.7 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 KFO95533.1 - 0.18 11.0 2.8 3.6 6.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KFO95533.1 - 0.2 11.3 1.8 4.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_5 PF13719.1 KFO95533.1 - 0.28 10.7 3.2 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFO95533.1 - 0.34 10.6 3.0 1.3 8.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KFO95533.1 - 1.5 8.4 6.7 0.98 8.9 0.2 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.5 KFO95533.1 - 2.7 7.5 4.6 4.9 6.7 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF2404 PF10296.4 KFO95535.1 - 5.9e-31 106.4 0.1 1.3e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ribosomal_L3 PF00297.17 KFO95536.1 - 6.9e-116 386.2 10.8 8.6e-116 385.9 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 HALZ PF02183.13 KFO95536.1 - 0.13 12.0 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper NDUFB10 PF10249.4 KFO95537.1 - 3.3e-55 185.6 5.7 4.1e-55 185.3 3.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Ribosomal_S5 PF00333.15 KFO95538.1 - 5.3e-29 99.7 0.5 9e-29 99.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KFO95538.1 - 5e-22 76.9 0.0 9.3e-22 76.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 KFO95538.1 - 0.98 9.9 4.7 2.1 8.8 3.3 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.27 KFO95539.1 - 1.1e-73 240.6 37.8 2e-09 36.9 0.3 10.9 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KFO95539.1 - 3.9e-49 165.9 2.7 6.3e-49 165.2 1.9 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KFO95539.1 - 0.00012 20.3 8.4 1.9 6.5 0.0 5.4 3 2 1 5 5 5 3 Nucleoporin Nup120/160 SH3_9 PF14604.1 KFO95540.1 - 1.4e-16 59.7 0.1 9.6e-11 41.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFO95540.1 - 9.3e-15 53.7 0.7 1.5e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KFO95540.1 - 2.5e-12 46.0 0.0 5.4e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KFO95540.1 - 5.3e-10 39.1 1.1 2.2e-09 37.0 0.5 2.1 2 1 0 2 2 2 1 PX domain p47_phox_C PF08944.6 KFO95540.1 - 7.2e-07 29.3 1.7 7.2e-07 29.3 1.2 2.0 2 0 0 2 2 2 1 NADPH oxidase subunit p47Phox, C terminal domain SH3_3 PF08239.6 KFO95540.1 - 1.1e-06 28.7 0.7 0.0019 18.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.8 KFO95540.1 - 0.0001 21.7 0.2 0.0017 17.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain Evr1_Alr PF04777.8 KFO95541.1 - 9.7e-30 102.3 3.0 1.2e-29 102.0 2.1 1.0 1 0 0 1 1 1 1 Erv1 / Alr family MARVEL PF01284.18 KFO95542.1 - 6.9e-24 84.2 12.0 9.1e-24 83.9 8.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3429 PF11911.3 KFO95542.1 - 0.031 14.2 0.6 0.031 14.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) RDD PF06271.7 KFO95542.1 - 0.75 9.6 6.7 2.9 7.7 1.6 2.2 2 0 0 2 2 2 0 RDD family DUF4131 PF13567.1 KFO95542.1 - 2.5 7.5 5.9 0.96 8.8 1.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) PEN-2 PF10251.4 KFO95542.1 - 4.4 7.6 8.4 0.68 10.2 2.5 1.9 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase zf-C2H2_4 PF13894.1 KFO95543.1 - 0.0093 16.2 0.7 0.0093 16.2 0.5 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO95543.1 - 0.015 15.5 0.6 0.015 15.5 0.4 5.5 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 KFO95543.1 - 3.7 7.7 22.7 1.1 9.4 1.7 4.5 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding EBP50_C-term PF09007.6 KFO95544.1 - 3.6e-23 81.1 1.9 6e-23 80.4 1.3 1.4 1 0 0 1 1 1 1 EBP50, C-terminal PDZ PF00595.19 KFO95544.1 - 8.7e-15 54.6 0.0 9.7e-14 51.3 0.0 2.3 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO95544.1 - 4.4e-06 26.4 0.0 1.1e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFO95544.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain HhH-GPD PF00730.20 KFO95545.1 - 1.1e-19 70.6 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KFO95545.1 - 2e-09 36.5 0.0 3.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 KFO95545.1 - 0.023 14.8 3.8 0.04 14.1 2.6 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Tuberin PF03542.11 KFO95546.1 - 3.9e-140 466.9 7.4 8.8e-140 465.7 5.2 1.6 1 0 0 1 1 1 1 Tuberin DUF3384 PF11864.3 KFO95546.1 - 3.2e-114 381.9 10.0 3.8e-113 378.4 4.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KFO95546.1 - 4.4e-45 153.3 0.0 7.5e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Prp18 PF02840.10 KFO95546.1 - 0.65 9.8 4.2 0.37 10.5 0.2 2.6 3 0 0 3 3 3 0 Prp18 domain PKD PF00801.15 KFO95547.1 - 2.2e-149 485.4 96.1 3.9e-15 55.3 0.5 17.6 18 0 0 18 18 18 15 PKD domain REJ PF02010.10 KFO95547.1 - 1e-106 356.9 0.0 1e-106 356.9 0.0 3.0 4 0 0 4 4 4 1 REJ domain PKD_channel PF08016.7 KFO95547.1 - 1.4e-97 326.8 16.6 2.1e-97 326.2 11.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel PLAT PF01477.18 KFO95547.1 - 2.7e-21 76.0 0.1 1.1e-20 74.0 0.1 2.1 1 0 0 1 1 1 1 PLAT/LH2 domain Lectin_C PF00059.16 KFO95547.1 - 1.4e-11 44.9 1.7 3e-11 43.8 0.3 2.4 2 0 0 2 2 2 1 Lectin C-type domain LRR_8 PF13855.1 KFO95547.1 - 3.1e-10 39.6 4.5 9.1e-10 38.1 3.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat Y_Y_Y PF07495.8 KFO95547.1 - 2.1e-08 33.7 11.3 0.2 11.4 0.0 6.9 7 0 0 7 7 6 3 Y_Y_Y domain GPS PF01825.16 KFO95547.1 - 5.7e-07 29.5 0.0 2.8e-06 27.3 0.0 2.3 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain WSC PF01822.14 KFO95547.1 - 6.1e-07 29.2 7.3 1.5e-06 28.0 5.1 1.7 1 0 0 1 1 1 1 WSC domain LRR_4 PF12799.2 KFO95547.1 - 0.0014 18.1 10.9 0.002 17.7 2.4 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO95547.1 - 0.06 13.3 2.8 2.4 8.5 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat DUF1727 PF08353.5 KFO95547.1 - 0.17 11.4 0.0 5.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) Ras PF00071.17 KFO95548.1 - 1e-59 200.5 0.2 1.2e-59 200.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95548.1 - 1.7e-18 67.2 0.0 2.9e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO95548.1 - 3.4e-14 52.4 0.1 3.8e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFO95548.1 - 4.6e-07 29.2 0.0 6.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFO95548.1 - 6.9e-05 22.3 0.1 0.00014 21.3 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFO95548.1 - 0.00065 19.0 0.2 0.004 16.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KFO95548.1 - 0.00093 19.1 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFO95548.1 - 0.0045 16.2 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFO95548.1 - 0.031 14.4 0.1 0.14 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KFO95548.1 - 0.036 13.0 0.2 0.1 11.6 0.1 1.8 1 1 0 1 1 1 0 Septin AAA PF00004.24 KFO95548.1 - 0.046 13.9 0.1 0.64 10.2 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KFO95548.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KFO95548.1 - 0.071 12.2 0.1 0.28 10.3 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 KFO95548.1 - 0.11 12.1 0.1 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Ser_hydrolase PF06821.8 KFO95548.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase WD40 PF00400.27 KFO95549.1 - 3.4e-47 156.7 26.0 4.5e-11 42.1 1.0 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Sina PF03145.11 KFO95549.1 - 2.6e-06 27.2 4.2 0.00097 18.8 0.3 2.5 2 0 0 2 2 2 2 Seven in absentia protein family zf-C3HC4_2 PF13923.1 KFO95549.1 - 3.3e-06 27.0 10.4 3.3e-06 27.0 7.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFO95549.1 - 2.8e-05 23.8 7.5 0.00012 21.9 5.2 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFO95549.1 - 3.8e-05 23.2 10.3 3.8e-05 23.2 7.1 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO95549.1 - 0.00047 19.8 13.5 0.0022 17.6 9.4 2.3 1 0 0 1 1 1 1 zinc-RING finger domain Nup160 PF11715.3 KFO95549.1 - 0.0007 17.8 7.6 0.0015 16.7 0.1 3.5 3 2 1 4 4 4 1 Nucleoporin Nup120/160 zf-C3HC4_3 PF13920.1 KFO95549.1 - 0.00091 18.8 11.8 0.00091 18.8 8.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PQQ_3 PF13570.1 KFO95549.1 - 0.013 15.7 1.7 2.1 8.7 0.0 4.5 5 1 0 5 5 5 0 PQQ-like domain zf-TRAF PF02176.13 KFO95549.1 - 0.024 15.0 4.8 0.024 15.0 3.4 3.0 3 1 0 3 3 2 0 TRAF-type zinc finger HSBP1 PF06825.7 KFO95549.1 - 0.069 12.7 1.6 0.14 11.7 1.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 PQQ_2 PF13360.1 KFO95549.1 - 0.085 12.3 0.4 0.62 9.4 0.1 2.3 1 1 0 2 2 2 0 PQQ-like domain zf-Nse PF11789.3 KFO95549.1 - 4.5 6.8 12.3 0.98 8.9 5.2 2.4 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Glyco_hydro_20 PF00728.17 KFO95550.1 - 2.8e-15 56.3 0.0 4.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain WD40 PF00400.27 KFO95552.1 - 9.7e-29 98.1 6.9 1.3e-08 34.4 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Hira PF07569.6 KFO95552.1 - 0.00029 20.1 0.2 0.1 11.7 0.0 2.5 2 1 1 3 3 3 2 TUP1-like enhancer of split Nup160 PF11715.3 KFO95552.1 - 0.0003 19.0 0.8 0.043 11.9 0.3 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 IKI3 PF04762.7 KFO95552.1 - 0.002 16.0 0.1 0.22 9.3 0.0 2.1 2 0 0 2 2 2 2 IKI3 family DUF2415 PF10313.4 KFO95552.1 - 0.059 13.0 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) BRICHOS PF04089.9 KFO95553.1 - 3.7e-14 52.3 0.1 5.5e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 BRICHOS domain DUF3068 PF11271.3 KFO95553.1 - 0.11 11.5 0.2 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) RhoGAP PF00620.22 KFO95554.1 - 9.8e-46 155.1 0.1 8.1e-45 152.1 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain BAR PF03114.13 KFO95554.1 - 8.9e-23 80.9 1.0 1.5e-22 80.2 0.7 1.4 1 0 0 1 1 1 1 BAR domain Hydrolase_like PF13242.1 KFO95554.1 - 8.1e-17 60.7 0.0 1.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KFO95554.1 - 0.00037 20.7 0.1 0.004 17.3 0.0 2.5 2 1 2 4 4 4 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KFO95554.1 - 0.0034 16.7 0.0 0.0094 15.3 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase PF00702.21 KFO95554.1 - 0.0086 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase APP_E2 PF12925.2 KFO95554.1 - 0.052 13.1 1.3 3.7 7.0 0.1 3.0 2 1 1 3 3 3 0 E2 domain of amyloid precursor protein Glyco_transf_10 PF00852.14 KFO95554.1 - 0.11 11.0 0.6 0.22 10.0 0.4 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) PAT1 PF09770.4 KFO95554.1 - 9.5 4.3 13.4 16 3.5 9.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2 PF00096.21 KFO95555.1 - 1.4e-40 135.2 68.9 0.00011 22.2 0.9 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO95555.1 - 9.9e-38 126.6 76.4 5.6e-08 32.6 1.1 10.9 12 0 0 12 12 12 9 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO95555.1 - 8e-32 107.2 56.2 0.00068 19.7 0.1 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO95555.1 - 6.5e-22 77.0 36.6 3e-05 24.0 0.3 10.3 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO95555.1 - 8.7e-13 47.6 58.9 3.3e-06 26.8 4.0 9.9 10 0 0 10 10 10 7 C2H2-type zinc finger zf-met PF12874.2 KFO95555.1 - 0.00098 19.2 0.5 0.00098 19.2 0.4 9.0 10 0 0 10 10 10 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFO95555.1 - 0.0041 16.7 38.0 0.24 11.1 0.2 8.1 8 0 0 8 8 8 3 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KFO95555.1 - 0.015 15.4 43.2 0.18 11.9 0.1 8.5 3 2 6 9 9 9 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.13 KFO95555.1 - 0.063 12.9 0.4 0.063 12.9 0.3 7.5 9 0 0 9 9 9 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFO95555.1 - 0.073 13.0 55.0 0.75 9.7 0.2 10.0 8 1 3 11 11 11 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO95555.1 - 0.1 12.4 50.7 0.046 13.5 1.8 7.0 5 2 2 7 7 7 0 Transposase zinc-ribbon domain zf-Di19 PF05605.7 KFO95555.1 - 0.46 10.6 36.5 5.3 7.2 3.7 7.1 4 2 3 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 KFO95555.1 - 7.7 7.1 19.9 6.7 7.3 0.1 6.6 6 1 1 7 7 7 0 Protein of unknown function (FYDLN_acid) FH2 PF02181.18 KFO95556.1 - 5.1e-90 302.0 9.5 7.2e-90 301.5 6.6 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain PDZ PF00595.19 KFO95556.1 - 9.6e-14 51.3 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO95556.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SSF PF00474.12 KFO95557.1 - 2.6e-144 480.8 20.2 3.4e-144 480.4 14.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Yeast_MT PF11403.3 KFO95557.1 - 0.38 10.9 4.3 0.18 11.9 0.6 2.0 2 0 0 2 2 2 0 Yeast metallothionein Gly_reductase PF09338.6 KFO95558.1 - 0.11 10.6 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits LCM PF04072.9 KFO95559.1 - 3.1e-35 121.3 0.0 4.3e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase MIP PF00230.15 KFO95560.1 - 0.00026 20.5 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.20 KFO95561.1 - 1.3e-62 211.2 0.0 1.9e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95561.1 - 8.9e-38 129.8 0.0 1.3e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.25 KFO95561.1 - 1e-25 89.3 0.2 1.7e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.17 KFO95561.1 - 3.2e-18 65.2 17.2 9.7e-17 60.4 4.2 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFO95561.1 - 1.6e-06 28.5 1.4 3.2e-06 27.5 1.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFO95561.1 - 0.0045 15.9 0.0 0.0093 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like CEP76-C2 PF15627.1 KFO95561.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain APH PF01636.18 KFO95561.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_3 PF07649.7 KFO95561.1 - 3.2 7.8 17.0 1.1 9.3 3.6 2.9 2 0 0 2 2 2 0 C1-like domain Pkinase_C PF00433.19 KFO95562.1 - 1.5e-11 44.6 2.4 1.7e-11 44.4 1.7 1.0 1 0 0 1 1 1 1 Protein kinase C terminal domain PMP22_Claudin PF00822.15 KFO95563.1 - 2.7e-33 114.9 0.6 3.8e-33 114.4 0.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO95563.1 - 4.6e-10 39.4 0.1 7.5e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 KFO95563.1 - 0.0035 16.6 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Tetraspanin family AtpR PF12966.2 KFO95563.1 - 0.14 12.3 0.9 0.37 10.9 0.1 2.0 2 0 0 2 2 2 0 N-ATPase, AtpR subunit DWNN PF08783.6 KFO95564.1 - 6.3e-32 109.3 0.1 2.1e-31 107.6 0.1 2.0 1 0 0 1 1 1 1 DWNN domain U-box PF04564.10 KFO95564.1 - 3.3e-07 30.1 0.0 1e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.1 KFO95564.1 - 5.6e-07 29.4 11.9 5.6e-07 29.4 8.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.18 KFO95564.1 - 1.3e-05 24.8 3.1 1.3e-05 24.8 2.1 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 KFO95564.1 - 3.9e-05 23.0 5.8 0.00014 21.2 4.0 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.1 KFO95564.1 - 0.00015 21.5 11.8 0.00028 20.6 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFO95564.1 - 0.0018 17.9 11.1 0.0018 17.9 7.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFO95564.1 - 0.0018 17.8 9.3 0.0018 17.8 6.5 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFO95564.1 - 0.0098 15.7 12.1 0.025 14.4 8.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFO95564.1 - 0.014 15.0 12.2 0.03 13.9 8.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFO95564.1 - 0.33 10.7 4.5 0.62 9.8 3.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ago_hook PF10427.4 KFO95565.1 - 2.2e-25 89.3 18.6 2.2e-25 89.3 12.9 12.3 5 2 6 12 12 12 1 Argonaute hook RRM_5 PF13893.1 KFO95565.1 - 4.2e-06 26.5 0.0 6.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO95565.1 - 0.0017 17.9 0.0 0.0051 16.4 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95565.1 - 0.0031 17.4 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PP-binding PF00550.20 KFO95566.1 - 2.3e-12 47.0 0.1 2.8e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KFO95566.1 - 0.00064 19.7 0.2 0.00074 19.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Hexapep PF00132.19 KFO95568.1 - 7.8e-17 59.9 19.7 1.4e-06 27.5 0.5 4.4 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFO95568.1 - 7.1e-06 25.4 13.4 0.00011 21.6 2.1 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KFO95568.1 - 0.078 11.5 0.1 0.099 11.1 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase EB PF01683.13 KFO95568.1 - 0.24 11.4 2.3 1.3 9.1 1.6 2.2 1 1 0 1 1 1 0 EB module Ribonuc_2-5A PF06479.7 KFO95569.1 - 1.3e-43 147.9 0.0 2.3e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KFO95569.1 - 5.1e-41 140.5 0.0 7e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95569.1 - 1.4e-23 83.2 0.0 2.2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KFO95569.1 - 5.5e-09 35.8 0.0 0.00092 18.7 0.0 2.9 2 1 2 4 4 4 3 PQQ-like domain PQQ PF01011.16 KFO95569.1 - 3.1e-07 29.5 0.1 0.022 14.2 0.0 3.1 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.9 KFO95569.1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO95569.1 - 0.02 14.6 1.2 2 8.0 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family PQQ_3 PF13570.1 KFO95569.1 - 0.026 14.7 3.6 30 5.0 0.0 5.6 7 0 0 7 7 7 0 PQQ-like domain ubiquitin PF00240.18 KFO95570.1 - 1.1e-10 40.7 0.0 2.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KFO95570.1 - 0.0018 18.4 0.0 0.013 15.6 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain DUF4249 PF14054.1 KFO95570.1 - 0.024 14.0 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Epimerase_2 PF02350.14 KFO95570.1 - 0.064 12.0 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase tRNA-synt_1c PF00749.16 KFO95571.1 - 2.1e-84 282.8 0.0 4.1e-84 281.9 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain VHS PF00790.14 KFO95572.1 - 5.2e-45 152.5 0.8 1.2e-43 148.1 0.0 2.6 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 KFO95572.1 - 1.4e-24 85.9 4.9 1.4e-24 85.9 3.4 1.9 2 0 0 2 2 2 1 GAT domain DUF2959 PF11172.3 KFO95572.1 - 0.002 17.9 0.7 0.0031 17.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Hrs_helical PF12210.3 KFO95572.1 - 0.094 12.9 2.3 0.12 12.6 0.5 2.0 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate 4HB_MCP_1 PF12729.2 KFO95572.1 - 0.83 8.9 7.1 0.43 9.8 2.5 2.1 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction PspB PF06667.7 KFO95572.1 - 0.96 9.4 3.7 2.1 8.3 0.2 2.8 1 1 1 2 2 2 0 Phage shock protein B FliT PF05400.8 KFO95572.1 - 1.5 9.2 12.8 2.8 8.4 1.1 2.5 2 0 0 2 2 2 0 Flagellar protein FliT Occludin_ELL PF07303.8 KFO95572.1 - 3.5 8.4 7.0 1.5 9.6 2.2 2.3 3 0 0 3 3 3 0 Occludin homology domain COG7 PF10191.4 KFO95573.1 - 0 1068.4 17.6 0 1068.3 12.2 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) COG5 PF10392.4 KFO95573.1 - 0.00075 19.4 9.4 0.0021 18.0 0.8 3.3 2 1 1 3 3 3 2 Golgi transport complex subunit 5 FlgN PF05130.7 KFO95573.1 - 0.031 14.5 10.4 2.3 8.4 3.8 3.5 3 1 0 3 3 3 0 FlgN protein DUF3340 PF11818.3 KFO95573.1 - 0.12 12.3 3.0 2.9 7.8 1.7 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) ASC PF00858.19 KFO95574.1 - 4.3e-105 351.9 6.3 6.9e-105 351.2 4.4 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.19 KFO95575.1 - 1.4e-100 336.9 8.7 1.7e-100 336.7 6.1 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel UCH PF00443.24 KFO95576.1 - 1.7e-43 148.6 0.0 4.3e-43 147.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO95576.1 - 1.2e-11 44.6 0.0 2e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF2296 PF10058.4 KFO95576.1 - 0.019 14.7 1.5 6.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-MIZ PF02891.15 KFO95576.1 - 0.36 10.3 9.3 0.33 10.4 3.6 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Sulfotransfer_1 PF00685.22 KFO95577.1 - 2.6e-35 121.9 0.0 3e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFO95577.1 - 0.0089 15.7 0.1 0.083 12.5 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family TLV_coat PF00429.14 KFO95578.1 - 0.055 11.9 0.2 0.062 11.7 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Sulfotransfer_1 PF00685.22 KFO95579.1 - 1.6e-45 155.4 0.0 1.9e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFO95579.1 - 0.0039 16.9 0.0 0.046 13.3 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_3 PF13469.1 KFO95579.1 - 0.036 14.9 0.0 0.099 13.5 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family Cupin_8 PF13621.1 KFO95580.1 - 7.9e-48 163.1 0.3 9.6e-48 162.8 0.2 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFO95580.1 - 1.7e-07 30.7 0.1 5.9e-07 29.0 0.1 1.7 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KFO95580.1 - 0.017 15.3 0.1 0.073 13.3 0.0 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase SMC_Nse1 PF07574.8 KFO95581.1 - 2.5e-40 138.2 0.9 1.1e-39 136.2 0.6 1.8 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KFO95581.1 - 5.8e-11 42.2 9.6 5.8e-11 42.2 6.7 2.4 3 0 0 3 3 3 1 RING-like domain zf-C3HC4_2 PF13923.1 KFO95581.1 - 0.00073 19.5 9.8 0.00073 19.5 6.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO95581.1 - 0.019 14.6 9.8 0.019 14.6 6.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DAP3 PF10236.4 KFO95581.1 - 0.039 12.8 0.1 0.053 12.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Multi-haem_cyto PF13447.1 KFO95581.1 - 1.2 8.1 11.1 0.51 9.3 5.1 2.0 2 1 1 3 3 3 0 Seven times multi-haem cytochrome CxxCH PHD PF00628.24 KFO95581.1 - 4.1 7.1 16.7 0.16 11.7 5.8 2.5 3 0 0 3 3 3 0 PHD-finger IL4Ra_N PF09238.5 KFO95582.1 - 1.6e-30 105.0 0.8 1.6e-30 105.0 0.6 1.9 2 0 0 2 2 2 1 Interleukin-4 receptor alpha chain, N-terminal IL6Ra-bind PF09240.5 KFO95582.1 - 1.2e-05 25.3 1.8 2.5e-05 24.3 1.2 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFO95582.1 - 7.3e-05 22.7 1.7 0.00021 21.2 1.1 1.9 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFO95582.1 - 0.0014 18.6 0.5 0.017 15.2 0.2 2.3 2 0 0 2 2 2 1 Fibronectin type III domain TTSSLRR PF12468.3 KFO95582.1 - 0.017 14.6 1.0 0.046 13.2 0.7 1.8 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein EpoR_lig-bind PF09067.5 KFO95583.1 - 0.0012 18.7 3.4 0.0013 18.7 1.1 2.0 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFO95583.1 - 0.015 15.4 0.1 0.045 13.8 0.1 1.7 1 0 0 1 1 1 0 Fibronectin type III domain LRR19-TM PF15176.1 KFO95583.1 - 0.16 11.6 4.5 0.045 13.4 0.7 1.8 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain fn3 PF00041.16 KFO95584.1 - 0.0019 18.2 0.5 0.003 17.6 0.4 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Tissue_fac PF01108.12 KFO95584.1 - 0.077 12.7 0.8 0.13 11.9 0.6 1.3 1 0 0 1 1 1 0 Tissue factor Pkinase PF00069.20 KFO95585.1 - 3.4e-66 223.0 0.0 4.5e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95585.1 - 3.8e-34 117.9 0.0 5.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 KFO95585.1 - 7.6e-30 102.8 0.0 1.5e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KFO95585.1 - 2e-07 30.2 0.0 3.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO95585.1 - 0.0031 16.5 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO95585.1 - 0.0096 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YukC PF10140.4 KFO95585.1 - 0.038 12.5 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC BTB_2 PF02214.17 KFO95586.1 - 3.1e-11 43.3 0.0 5.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFO95586.1 - 0.012 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF4206 PF13901.1 KFO95586.1 - 0.054 13.0 0.1 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) UQ_con PF00179.21 KFO95587.1 - 9.4e-49 164.4 0.0 1.1e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFO95587.1 - 0.00017 21.3 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF367 PF04034.8 KFO95588.1 - 4.4e-51 171.7 0.0 5.5e-51 171.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KFO95588.1 - 3.2e-12 45.8 1.1 5.6e-12 45.0 0.8 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PRKCSH_1 PF13015.1 KFO95589.1 - 5.8e-10 38.8 0.1 3.4e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KFO95589.1 - 6.6e-07 30.0 2.7 6.6e-07 30.0 1.9 2.1 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF3347 PF11827.3 KFO95589.1 - 0.019 14.9 0.8 0.019 14.9 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) P-mevalo_kinase PF04275.9 KFO95589.1 - 0.046 13.4 0.2 0.1 12.3 0.1 1.6 1 1 0 1 1 1 0 Phosphomevalonate kinase Ribosomal_S8 PF00410.14 KFO95589.1 - 0.089 12.6 0.6 0.18 11.6 0.3 1.5 2 0 0 2 2 2 0 Ribosomal protein S8 DUF4582 PF15189.1 KFO95589.1 - 0.1 11.8 0.9 0.18 11.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Transposase_22 PF02994.9 KFO95589.1 - 0.33 9.4 5.1 0.39 9.1 3.6 1.1 1 0 0 1 1 1 0 L1 transposable element zf-C3HC4_3 PF13920.1 KFO95590.1 - 4.9e-10 38.9 10.3 4.9e-10 38.9 7.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 KFO95590.1 - 1.9e-05 24.2 2.2 1.9e-05 24.2 1.6 6.6 7 0 0 7 7 7 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mnd1 PF03962.10 KFO95590.1 - 0.00016 21.3 0.2 0.00095 18.8 0.5 2.0 2 0 0 2 2 2 1 Mnd1 family Aida_N PF08910.5 KFO95590.1 - 0.042 14.0 2.5 0.1 12.8 1.7 1.6 1 0 0 1 1 1 0 Aida N-terminus DUF342 PF03961.8 KFO95590.1 - 0.15 10.4 0.8 0.23 9.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 KFO95590.1 - 0.23 8.7 7.2 0.37 8.0 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 KFO95590.1 - 0.27 10.6 10.7 0.021 14.3 4.1 1.5 2 0 0 2 2 2 0 Intermediate filament protein APC_CDC26 PF10471.4 KFO95590.1 - 1.1 10.0 7.7 46 4.8 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 zf-C3HC4_2 PF13923.1 KFO95590.1 - 2.3 8.3 21.2 0.068 13.2 9.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Borrelia_P83 PF05262.6 KFO95590.1 - 8.9 4.4 12.4 14 3.8 8.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Sulfotransfer_1 PF00685.22 KFO95593.1 - 4.8e-26 91.5 0.4 6.5e-26 91.1 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFO95593.1 - 2.3e-06 28.6 0.1 6.8e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family PsbM PF05151.7 KFO95593.1 - 0.05 13.2 1.3 0.088 12.4 0.9 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) TM231 PF10149.4 KFO95594.1 - 2.3e-105 352.1 0.8 2.7e-105 351.9 0.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 A_deamin PF02137.13 KFO95595.1 - 1.2e-112 376.6 0.7 1.6e-112 376.2 0.5 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain tRNA-synt_2 PF00152.15 KFO95596.1 - 3.7e-90 302.1 0.2 5e-90 301.6 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFO95596.1 - 3.7e-16 58.7 0.0 2e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFO95596.1 - 6.4e-08 32.0 0.0 0.0024 17.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KFO95596.1 - 0.0072 15.9 0.1 3.1 7.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Dec-1 PF04624.9 KFO95596.1 - 0.075 12.6 0.4 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 Dec-1 repeat Sulfotransfer_1 PF00685.22 KFO95597.1 - 7.2e-28 97.5 0.1 1e-27 97.0 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFO95597.1 - 7.5e-07 30.1 0.0 2.7e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Aminotran_1_2 PF00155.16 KFO95598.1 - 5.5e-73 246.0 0.0 6.3e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TAT_ubiq PF07706.7 KFO95598.1 - 7.8e-11 41.7 0.7 1.2e-10 41.1 0.5 1.3 1 0 0 1 1 1 1 Aminotransferase ubiquitination site Beta_elim_lyase PF01212.16 KFO95598.1 - 1.6e-06 27.4 0.0 2.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFO95598.1 - 4.7e-06 25.5 0.0 8.6e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KFO95598.1 - 0.012 13.9 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Bunya_RdRp PF04196.7 KFO95598.1 - 0.14 10.1 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase MARVEL PF01284.18 KFO95599.1 - 2.6e-06 27.3 4.7 3.6e-06 26.8 3.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Yip1 PF04893.12 KFO95599.1 - 0.14 11.6 6.4 0.39 10.2 4.5 1.8 1 1 0 1 1 1 0 Yip1 domain DUF997 PF06196.7 KFO95599.1 - 1.7 8.2 7.6 1.1 8.7 2.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF997) DUF202 PF02656.10 KFO95599.1 - 4.7 7.4 7.9 5 7.4 0.3 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF202) Consortin_C PF15281.1 KFO95599.1 - 4.9 6.6 7.0 2.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Consortin C-terminus DUF490 PF04357.8 KFO95600.1 - 0.096 11.7 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF490) DUF4131 PF13567.1 KFO95600.1 - 3.1 7.1 5.6 4.2 6.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Adaptin_N PF01602.15 KFO95601.1 - 1.6e-152 508.5 8.9 1.9e-152 508.2 6.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KFO95601.1 - 5.5e-32 110.4 4.8 1.1e-31 109.5 3.3 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain IL31 PF15209.1 KFO95601.1 - 0.013 15.0 0.2 0.043 13.4 0.0 2.0 2 0 0 2 2 2 0 Interleukin 31 CLASP_N PF12348.3 KFO95601.1 - 0.034 13.5 0.8 0.26 10.5 0.1 2.6 2 0 0 2 2 2 0 CLASP N terminal AXH PF08517.7 KFO95602.1 - 1.4e-39 134.8 0.0 2.4e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) zf-met PF12874.2 KFO95603.1 - 5e-06 26.5 3.9 1.7 8.9 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KFO95603.1 - 0.0001 22.4 1.6 0.66 10.3 0.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO95603.1 - 0.00014 21.9 10.4 0.26 11.6 0.0 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO95603.1 - 0.0076 16.3 0.1 16 5.7 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFO95603.1 - 0.011 16.0 0.0 0.011 16.0 0.0 3.7 4 0 0 4 4 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 KFO95603.1 - 0.018 15.1 5.5 0.13 12.3 3.8 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 KFO95603.1 - 0.019 14.4 4.0 0.18 11.3 0.0 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif DZR PF12773.2 KFO95603.1 - 0.02 14.7 2.6 0.044 13.6 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 KFO95603.1 - 0.33 10.4 2.6 8.5 5.9 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 KFO95603.1 - 0.59 9.4 3.4 0.77 9.0 0.3 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-tcix PF14952.1 KFO95603.1 - 0.64 9.3 3.2 1.1 8.5 0.0 2.8 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding PhnA_Zn_Ribbon PF08274.7 KFO95603.1 - 1.8 8.4 11.2 11 5.9 0.1 3.7 4 0 0 4 4 4 0 PhnA Zinc-Ribbon Prok-RING_4 PF14447.1 KFO95603.1 - 4.9 6.7 5.6 35 4.0 0.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Peptidase_S46 PF10459.4 KFO95603.1 - 7 4.9 11.6 9.6 4.4 8.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Ist1 PF03398.9 KFO95604.1 - 1.9e-60 202.9 4.1 2.4e-60 202.7 2.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DHO_dh PF01180.16 KFO95605.1 - 2.9e-106 354.7 0.0 3.6e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 KFO95605.1 - 0.083 12.1 0.1 9.2 5.4 0.0 2.1 2 0 0 2 2 2 0 PcrB family OB_NTP_bind PF07717.11 KFO95606.1 - 1e-25 89.7 0.1 4.1e-25 87.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFO95606.1 - 5.2e-19 68.1 0.0 5.2e-19 68.1 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFO95606.1 - 3.5e-13 49.2 0.0 8.2e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFO95606.1 - 1.4e-07 31.1 0.7 1.1e-06 28.2 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFO95606.1 - 3.6e-06 27.1 0.0 9.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFO95606.1 - 0.0016 17.4 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 KFO95606.1 - 0.0025 17.5 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 KFO95606.1 - 0.0044 16.8 0.8 1.7 8.4 0.0 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KFO95606.1 - 0.0057 16.3 0.0 0.02 14.5 0.0 1.9 1 0 0 1 1 1 1 Archaeal ATPase PhoH PF02562.11 KFO95606.1 - 0.02 14.1 0.0 0.047 12.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 KFO95606.1 - 0.023 14.7 0.0 0.33 10.9 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain SRP54 PF00448.17 KFO95606.1 - 0.046 13.1 0.1 0.1 11.9 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Homeobox PF00046.24 KFO95607.1 - 2.9e-65 215.7 19.6 4.5e-17 61.4 0.5 5.0 4 0 0 4 4 4 4 Homeobox domain Homeobox_KN PF05920.6 KFO95607.1 - 2.7e-11 42.9 0.6 0.087 12.5 0.0 4.7 4 0 0 4 4 4 3 Homeobox KN domain zf-C2H2 PF00096.21 KFO95607.1 - 3.3e-08 33.4 161.8 0.011 16.0 0.3 22.3 24 0 0 24 24 24 12 Zinc finger, C2H2 type zf-met PF12874.2 KFO95607.1 - 2.7e-07 30.5 97.2 0.00033 20.7 0.6 16.1 16 0 0 16 16 16 7 Zinc-finger of C2H2 type MerR_1 PF13411.1 KFO95607.1 - 0.018 14.7 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 0 MerR HTH family regulatory protein zf-C2H2_4 PF13894.1 KFO95607.1 - 0.09 13.1 141.9 0.23 11.8 2.4 20.8 22 0 0 22 22 22 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFO95607.1 - 0.16 12.2 132.6 0.023 14.9 3.7 17.1 18 0 0 18 18 18 0 C2H2-type zinc-finger domain Lamprin PF06403.6 KFO95608.1 - 1.3e-05 24.9 16.5 0.0012 18.5 2.5 2.0 1 1 1 2 2 2 2 Lamprin MitMem_reg PF13012.1 KFO95609.1 - 4.8e-40 136.2 0.2 1.6e-39 134.5 0.3 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KFO95609.1 - 5.9e-23 80.7 0.8 2.3e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNase_H2-Ydr279 PF09468.5 KFO95609.1 - 0.017 14.3 4.2 0.022 13.9 2.9 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) BSMAP PF12280.3 KFO95609.1 - 0.15 11.9 1.0 0.21 11.4 0.7 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein OAD_gamma PF04277.8 KFO95609.1 - 0.26 11.6 1.5 0.63 10.4 1.1 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain YqfQ PF14181.1 KFO95609.1 - 1.5 8.8 8.8 2.4 8.1 6.1 1.3 1 0 0 1 1 1 0 YqfQ-like protein Bap31 PF05529.7 KFO95609.1 - 3.9 6.8 7.3 6.1 6.2 5.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like HECT PF00632.20 KFO95610.1 - 2e-98 329.4 0.5 2.9e-98 328.9 0.3 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFO95610.1 - 2.2e-47 158.5 34.7 4.3e-14 52.0 2.5 4.5 4 0 0 4 4 4 4 WW domain Neil1-DNA_bind PF09292.5 KFO95610.1 - 2.4 8.0 5.3 1.1 9.0 0.1 3.0 3 0 0 3 3 3 0 Endonuclease VIII-like 1, DNA bind RHD PF00554.17 KFO95611.1 - 4.3e-21 75.3 0.1 3e-20 72.6 0.1 2.5 1 1 0 1 1 1 1 Rel homology domain (RHD) TRF PF08558.5 KFO95612.1 - 5.1e-20 71.8 0.5 9e-20 71.0 0.3 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KFO95612.1 - 2.6e-11 43.3 3.0 3.4e-11 43.0 0.7 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFO95612.1 - 0.00081 19.4 3.3 0.00093 19.2 0.7 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4062 PF13271.1 KFO95612.1 - 0.035 14.1 0.1 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4062) Ribosomal_L36e PF01158.13 KFO95612.1 - 0.037 13.9 2.6 0.079 12.9 1.8 1.6 1 0 0 1 1 1 0 Ribosomal protein L36e Myb_DNA-bind_5 PF13873.1 KFO95612.1 - 0.84 9.5 5.8 0.18 11.7 0.4 2.5 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain EMP24_GP25L PF01105.19 KFO95613.1 - 1.8e-29 102.7 0.1 2e-29 102.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0113 PF03657.8 KFO95614.1 - 7.5e-06 25.7 0.0 9.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KFO95614.1 - 0.041 13.6 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 PUA domain Nol1_Nop2_Fmu_2 PF13636.1 KFO95614.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis Dor1 PF04124.7 KFO95615.1 - 7.4e-121 402.7 0.0 9.1e-121 402.4 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.6 KFO95615.1 - 0.0024 17.6 0.0 0.0096 15.7 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 KFO95615.1 - 0.039 13.6 0.0 0.37 10.4 0.0 2.3 3 0 0 3 3 3 0 Exocyst complex component Sec5 Vps4_C PF09336.5 KFO95617.1 - 3.8e-27 93.9 0.1 6.7e-27 93.1 0.1 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA PF00004.24 KFO95617.1 - 0.00013 22.1 0.0 0.00034 20.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KFO95618.1 - 8.5e-31 106.8 0.0 1.4e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFO95618.1 - 2.7e-07 30.7 0.1 6e-05 23.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFO95618.1 - 3.9e-07 29.6 0.2 0.0075 15.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.8 KFO95618.1 - 1.7e-06 27.0 0.0 2.2e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KFO95618.1 - 2.3e-06 27.1 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 KFO95618.1 - 7.7e-06 26.0 0.0 0.001 19.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFO95618.1 - 9.5e-06 26.4 0.0 1.6e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFO95618.1 - 1e-05 25.4 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFO95618.1 - 1.9e-05 24.3 0.0 5.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFO95618.1 - 2.9e-05 23.2 0.0 3.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFO95618.1 - 8.3e-05 22.4 0.0 0.00018 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFO95618.1 - 9.4e-05 21.4 0.0 0.00012 21.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 KFO95618.1 - 0.00026 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KFO95618.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KFO95618.1 - 0.0013 18.4 0.0 0.086 12.4 0.0 2.2 1 1 1 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 KFO95618.1 - 0.0019 17.9 0.0 0.27 10.8 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase KaiC PF06745.8 KFO95618.1 - 0.0021 17.1 0.1 0.85 8.6 0.0 2.1 1 1 1 2 2 2 2 KaiC Zeta_toxin PF06414.7 KFO95618.1 - 0.0026 16.8 0.0 0.01 14.9 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 KFO95618.1 - 0.0029 17.7 0.0 0.0046 17.0 0.0 1.6 1 1 0 1 1 1 1 RNA helicase ResIII PF04851.10 KFO95618.1 - 0.0042 16.9 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KFO95618.1 - 0.005 16.1 0.1 0.0071 15.5 0.1 1.5 1 1 0 1 1 1 1 PhoH-like protein Sigma54_activ_2 PF14532.1 KFO95618.1 - 0.0054 16.7 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFO95618.1 - 0.0064 15.6 0.2 0.016 14.3 0.0 1.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Guanylate_kin PF00625.16 KFO95618.1 - 0.0096 15.3 0.0 0.063 12.7 0.0 2.0 1 1 0 2 2 2 1 Guanylate kinase Sigma54_activat PF00158.21 KFO95618.1 - 0.011 15.1 0.0 0.047 13.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KFO95618.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 KFO95618.1 - 0.027 13.4 0.1 0.16 10.9 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.1 KFO95618.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFO95618.1 - 0.031 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain MCM PF00493.18 KFO95618.1 - 0.033 13.0 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_24 PF13479.1 KFO95618.1 - 0.056 13.0 0.2 0.084 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KFO95618.1 - 0.06 12.2 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_21 PF13304.1 KFO95618.1 - 0.06 13.2 0.2 2.6 7.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 KFO95618.1 - 0.081 11.7 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase AAA_10 PF12846.2 KFO95618.1 - 0.092 12.1 0.1 0.51 9.7 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain AAA_30 PF13604.1 KFO95618.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFO95618.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter KTI12 PF08433.5 KFO95618.1 - 0.12 11.5 0.1 0.29 10.2 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 KFO95618.1 - 0.12 11.2 0.0 0.34 9.8 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KFO95618.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KFO95618.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin PDZ PF00595.19 KFO95619.1 - 2.2e-06 27.7 0.1 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH PF00169.24 KFO95619.1 - 2.5e-05 24.4 0.0 0.019 15.1 0.0 2.3 2 0 0 2 2 2 2 PH domain WD40 PF00400.27 KFO95620.1 - 1.4e-10 40.5 16.1 0.00017 21.3 0.1 6.6 6 1 1 7 7 7 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFO95620.1 - 0.028 13.2 0.0 0.04 12.6 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Ctf8 PF09696.5 KFO95621.1 - 6.8e-16 58.1 0.0 8.4e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Chitin_synth_2 PF03142.10 KFO95622.1 - 3.7e-14 52.0 2.3 9.4e-10 37.4 1.6 3.3 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KFO95622.1 - 7.4e-13 48.8 0.1 2.5e-08 33.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KFO95622.1 - 2.4e-08 33.9 8.2 2.4e-08 33.9 5.7 1.9 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KFO95622.1 - 8.9e-05 22.2 0.0 0.00089 18.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 NeA_P2 PF12312.3 KFO95622.1 - 0.007 15.6 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Nepovirus subgroup A polyprotein DUF2435 PF10363.4 KFO95623.1 - 8.5e-21 73.6 3.1 9.5e-21 73.5 0.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KFO95623.1 - 6.3e-09 35.1 1.4 2.4e-08 33.2 0.9 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) HEAT_2 PF13646.1 KFO95623.1 - 6.6e-06 26.3 5.9 0.021 15.0 0.4 3.5 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 KFO95623.1 - 0.00029 20.6 4.0 6.8 7.0 0.1 6.1 4 1 1 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KFO95623.1 - 0.00062 20.1 12.3 0.0014 19.0 0.1 5.6 5 0 0 5 5 5 1 HEAT-like repeat TPR_12 PF13424.1 KFO95623.1 - 0.033 14.1 0.2 17 5.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Transthyretin PF00576.16 KFO95624.1 - 2.7e-24 85.2 0.0 2.9e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family GAS PF13851.1 KFO95625.1 - 4.4e-65 218.6 32.9 4.4e-65 218.6 22.8 3.1 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Dysbindin PF04440.11 KFO95626.1 - 6.4e-40 136.2 0.0 7.6e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) DUF4206 PF13901.1 KFO95627.1 - 2.5e-69 232.8 11.4 2.5e-69 232.8 7.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4206) C1_1 PF00130.17 KFO95627.1 - 1.9e-06 27.5 7.9 1.9e-06 27.5 5.5 4.5 3 2 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFO95627.1 - 0.012 15.2 11.8 0.012 15.2 8.2 4.3 3 2 0 3 3 3 0 Prokaryotic RING finger family 1 Tubulin PF00091.20 KFO95628.1 - 3.4e-61 206.8 0.0 5.3e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFO95628.1 - 8.4e-50 168.0 0.1 1.4e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFO95628.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tcf25 PF04910.9 KFO95631.1 - 1.1e-112 376.5 5.2 1.1e-112 376.5 3.6 1.9 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TPR_12 PF13424.1 KFO95631.1 - 0.048 13.6 2.1 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PrmA PF06325.8 KFO95632.1 - 0.0078 15.3 0.1 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) WH2 PF02205.15 KFO95632.1 - 0.019 14.5 0.4 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 WH2 motif FYVE_2 PF02318.11 KFO95632.1 - 0.16 11.8 6.5 0.4 10.5 4.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Fanconi_A PF03511.9 KFO95633.1 - 4.4e-10 39.1 0.5 1.9e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 Fanconi anaemia group A protein zf-C2H2_4 PF13894.1 KFO95634.1 - 6e-15 54.3 36.6 0.0025 18.0 0.8 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO95634.1 - 1.2e-13 50.5 41.3 0.0001 22.4 1.6 6.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO95634.1 - 1.8e-11 43.7 45.9 0.00018 21.6 0.1 7.2 7 0 0 7 7 7 4 Zinc-finger double domain Zn-ribbon_8 PF09723.5 KFO95634.1 - 0.12 12.2 22.6 0.21 11.5 0.0 4.8 4 1 0 4 4 4 0 Zinc ribbon domain ADK_lid PF05191.9 KFO95634.1 - 0.83 9.3 13.4 0.44 10.2 0.1 4.5 5 0 0 5 5 5 0 Adenylate kinase, active site lid DUF2197 PF09963.4 KFO95634.1 - 2.2 8.3 10.2 0.42 10.5 0.4 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2_6 PF13912.1 KFO95634.1 - 2.5 8.1 20.6 1.8 8.6 0.4 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger IBR PF01485.16 KFO95634.1 - 5.3 7.0 26.3 4 7.3 0.3 4.9 2 1 1 3 3 3 0 IBR domain Pkinase PF00069.20 KFO95635.1 - 7.8e-68 228.4 0.0 9e-68 228.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95635.1 - 3.2e-35 121.4 0.0 4.5e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO95635.1 - 9.8e-11 41.1 0.0 3.2e-07 29.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 KFO95635.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.3 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 KFO95635.1 - 0.041 13.6 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFO95635.1 - 0.057 12.4 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF244 PF03112.9 KFO95635.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Herpes_IE1 PF07340.6 KFO95635.1 - 0.12 10.8 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Snf7 PF03357.16 KFO95636.1 - 2.8e-17 62.6 16.6 3.6e-17 62.2 11.5 1.1 1 0 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 KFO95636.1 - 0.0059 16.4 1.3 0.0059 16.4 0.9 1.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Ist1 PF03398.9 KFO95636.1 - 0.03 13.7 6.1 0.056 12.8 4.3 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Mo25 PF08569.6 KFO95636.1 - 0.042 12.8 1.5 0.061 12.3 1.0 1.2 1 0 0 1 1 1 0 Mo25-like Spore_YpjB PF09577.5 KFO95636.1 - 0.098 12.2 5.1 0.16 11.5 3.6 1.4 1 1 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) FliG_N PF14842.1 KFO95636.1 - 0.24 11.5 4.2 0.093 12.8 1.0 1.8 2 1 0 2 2 2 0 FliG N-terminal domain GrpE PF01025.14 KFO95636.1 - 0.25 10.8 5.8 0.39 10.2 4.0 1.5 1 1 0 1 1 1 0 GrpE Wbp11 PF09429.5 KFO95636.1 - 0.52 10.3 0.1 0.52 10.3 0.0 2.6 3 0 0 3 3 3 0 WW domain binding protein 11 Cytochrom_B562 PF07361.6 KFO95636.1 - 1.5 9.2 10.1 0.12 12.8 2.6 2.1 2 0 0 2 2 2 0 Cytochrome b562 Lge1 PF11488.3 KFO95636.1 - 3.3 7.9 6.4 1.5 9.0 1.4 2.5 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Peptidase_M19 PF01244.16 KFO95637.1 - 7.7e-46 156.4 1.0 8.2e-46 156.3 0.7 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Copine PF07002.11 KFO95638.1 - 3.2e-62 208.5 0.0 5.4e-62 207.8 0.0 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.25 KFO95638.1 - 1.8e-29 101.4 0.1 1.6e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFO95638.1 - 8e-08 32.3 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 KFO95638.1 - 0.0036 17.0 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L13e PF01294.13 KFO95639.1 - 1.2e-90 301.8 7.5 1.5e-90 301.4 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Peptidase_M41 PF01434.13 KFO95640.1 - 1.4e-69 233.8 0.0 2.3e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFO95640.1 - 3.7e-39 133.9 0.0 1e-38 132.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFO95640.1 - 1e-06 28.5 0.3 1.5e-05 24.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.10 KFO95640.1 - 5.5e-06 26.5 0.0 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.1 KFO95640.1 - 0.00018 21.5 0.1 0.0038 17.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFO95640.1 - 0.00019 21.6 0.1 0.028 14.5 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_2 PF07724.9 KFO95640.1 - 0.00068 19.5 1.2 0.0015 18.4 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KFO95640.1 - 0.0012 19.6 0.0 0.0072 17.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KFO95640.1 - 0.0015 17.6 0.0 0.0044 16.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KFO95640.1 - 0.0033 16.1 0.1 0.0057 15.4 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KFO95640.1 - 0.0052 16.5 0.2 0.028 14.1 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KFO95640.1 - 0.0075 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFO95640.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NAD_binding_1 PF00175.16 KFO95640.1 - 0.018 15.6 0.0 0.15 12.5 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain AAA_28 PF13521.1 KFO95640.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFO95640.1 - 0.025 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFO95640.1 - 0.067 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFO95640.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KFO95640.1 - 0.088 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.1 KFO95640.1 - 0.11 12.5 0.0 1.5 8.8 0.0 2.4 1 1 1 2 2 2 0 Sigma-54 interaction domain Peptidase_M50B PF13398.1 KFO95640.1 - 0.49 9.7 2.9 0.34 10.2 0.0 2.1 3 0 0 3 3 3 0 Peptidase M50B-like Ank PF00023.25 KFO95641.1 - 5.4e-24 82.7 0.2 6.3e-07 28.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFO95641.1 - 6.1e-24 84.1 0.3 2.4e-13 50.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFO95641.1 - 1.4e-19 69.6 0.4 2.7e-09 36.9 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO95641.1 - 1.4e-15 57.2 0.9 1.9e-09 37.7 0.1 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO95641.1 - 6.9e-14 50.5 0.2 0.00055 19.9 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat YcbB PF08664.5 KFO95642.1 - 0.07 12.9 4.1 0.067 12.9 0.9 2.2 2 0 0 2 2 2 0 YcbB domain AMP-binding PF00501.23 KFO95643.1 - 1.7e-82 277.0 0.1 2.8e-82 276.3 0.1 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO95643.1 - 1.1e-12 48.6 0.2 3e-12 47.3 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TAFH PF07531.9 KFO95645.1 - 1.7e-35 120.5 0.7 3.3e-35 119.6 0.5 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF NHR2 PF08788.6 KFO95645.1 - 7.2e-28 95.8 1.5 2.1e-27 94.3 1.1 1.8 1 0 0 1 1 1 1 NHR2 domain like zf-MYND PF01753.13 KFO95645.1 - 4e-08 33.0 17.1 4e-08 33.0 11.9 2.1 2 0 0 2 2 2 1 MYND finger vATP-synt_E PF01991.13 KFO95645.1 - 2.1 7.5 10.0 3.4 6.8 7.0 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit RRM_1 PF00076.17 KFO95646.1 - 9.6e-18 63.5 0.0 1.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95646.1 - 1.2e-13 50.8 0.0 1.7e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95646.1 - 8.7e-09 35.1 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sedlin_N PF04628.8 KFO95647.1 - 1.6e-36 125.0 0.5 1.8e-36 124.9 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KFO95647.1 - 4.3e-10 39.4 0.2 5.2e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Sybindin-like family Glyco_transf_21 PF13506.1 KFO95647.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 2 0 0 2 2 2 0 Glycosyl transferase family 21 Sulfatase PF00884.18 KFO95648.1 - 4.9e-79 265.7 0.0 6.6e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFO95648.1 - 5.9e-37 126.8 0.0 1.1e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFO95648.1 - 1.5e-09 37.6 0.0 3.3e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFO95648.1 - 0.14 10.5 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Pribosyltran PF00156.22 KFO95649.1 - 5.2e-24 84.3 0.0 6.3e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFO95649.1 - 0.00022 20.5 0.0 0.00031 20.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KFO95649.1 - 0.03 13.6 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase CDT1 PF08839.6 KFO95650.1 - 1.2e-56 191.1 0.1 1.7e-55 187.4 0.0 2.4 3 0 0 3 3 3 1 DNA replication factor CDT1 like zf-Di19 PF05605.7 KFO95651.1 - 1.3e-17 63.6 3.3 1.3e-17 63.6 2.3 3.0 2 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Rubredoxin PF00301.15 KFO95651.1 - 0.0015 18.3 3.5 2.8 7.9 0.0 3.6 3 0 0 3 3 3 1 Rubredoxin UIM PF02809.15 KFO95651.1 - 0.0024 17.2 3.8 0.0043 16.5 2.7 1.4 1 0 0 1 1 1 1 Ubiquitin interaction motif PhnA_Zn_Ribbon PF08274.7 KFO95651.1 - 0.028 14.2 1.8 3.2 7.6 0.0 4.0 3 1 0 3 3 3 0 PhnA Zinc-Ribbon DUF4187 PF13821.1 KFO95651.1 - 0.078 12.5 0.2 0.27 10.8 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zinc_ribbon_2 PF13240.1 KFO95651.1 - 0.11 12.0 0.1 0.11 12.0 0.0 4.2 5 0 0 5 5 5 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFO95651.1 - 0.29 10.3 0.0 0.29 10.3 0.0 4.3 5 0 0 5 5 4 0 zinc-ribbon domain Nairovirus_M PF07948.6 KFO95651.1 - 0.72 7.9 7.0 1.4 6.9 1.1 2.1 2 0 0 2 2 2 0 Nairovirus M polyprotein-like Zn_Tnp_IS1595 PF12760.2 KFO95651.1 - 0.73 9.6 15.1 0.94 9.3 0.2 3.9 2 1 0 3 3 3 0 Transposase zinc-ribbon domain zf-C2H2_4 PF13894.1 KFO95651.1 - 1.4 9.4 16.9 1.5 9.3 0.5 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.10 KFO95651.1 - 2 8.2 10.1 0.51 10.1 0.3 3.4 3 1 0 3 3 3 0 BED zinc finger GHMP_kinases_N PF00288.21 KFO95652.1 - 2.2e-08 34.0 1.1 2.2e-08 34.0 0.8 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFO95652.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal zf-CCCH PF00642.19 KFO95653.1 - 0.00052 19.6 3.3 0.00089 18.8 2.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFO95653.1 - 0.44 10.6 4.2 0.79 9.8 2.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type CIDE-N PF02017.10 KFO95654.1 - 2.9e-12 46.1 0.0 5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 CIDE-N domain BEN PF10523.4 KFO95655.1 - 1.5e-10 40.9 0.1 3.5e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 BEN domain Tbf5 PF06331.7 KFO95655.1 - 0.02 14.6 0.5 0.049 13.4 0.3 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Carb_anhydrase PF00194.16 KFO95656.1 - 3.6e-108 360.3 0.0 4.4e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AA_permease_2 PF13520.1 KFO95657.1 - 1e-63 215.3 42.9 1.2e-63 215.1 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFO95657.1 - 1.7e-25 89.2 38.8 2.4e-25 88.8 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease MORN PF02493.15 KFO95658.1 - 1.4e-41 137.7 67.5 8e-10 37.8 0.6 8.6 8 0 0 8 8 8 8 MORN repeat Herpes_capsid PF06112.6 KFO95658.1 - 1.8 8.5 7.2 0.091 12.8 1.0 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SAM_1 PF00536.25 KFO95659.1 - 1.2e-05 25.4 0.6 2.4e-05 24.4 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CCHC PF00098.18 KFO95659.1 - 3.5e-05 23.4 1.8 3.5e-05 23.4 1.3 2.2 2 0 0 2 2 2 1 Zinc knuckle SAM_2 PF07647.12 KFO95659.1 - 0.0016 18.2 0.3 0.003 17.3 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Atg8 PF02991.11 KFO95660.1 - 1.3e-43 147.1 0.2 1.5e-43 147.0 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFO95660.1 - 1.2e-06 28.5 0.0 1.5e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2407 PF10302.4 KFO95660.1 - 0.032 14.4 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 KFO95660.1 - 0.057 13.1 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing DUF3506 PF12014.3 KFO95661.1 - 2.3e-05 24.2 1.1 0.0078 16.0 0.1 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3506) DUF4106 PF13388.1 KFO95661.1 - 0.94 8.3 3.4 12 4.7 2.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4106) SBF2 PF12335.3 KFO95662.1 - 0.00015 21.1 1.2 0.00015 21.1 0.8 1.9 2 1 0 2 2 2 1 Myotubularin protein Sld5 PF05916.6 KFO95663.1 - 1.6e-12 47.7 0.7 1.7e-12 47.5 0.5 1.0 1 0 0 1 1 1 1 GINS complex protein UPF0172 PF03665.8 KFO95664.1 - 1.9e-75 252.6 0.0 2.1e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) BBS2_Mid PF14783.1 KFO95664.1 - 0.036 13.8 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region COX4 PF02936.9 KFO95665.1 - 4.9e-47 159.2 0.4 5.6e-47 159.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV PepSY_TM_1 PF13172.1 KFO95665.1 - 0.09 12.5 1.0 0.14 11.9 0.7 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix IRF-3 PF10401.4 KFO95666.1 - 1.4e-62 210.4 0.4 2.1e-62 209.9 0.2 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 KFO95666.1 - 1.8e-46 156.4 0.9 3.4e-46 155.5 0.6 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor tRNA-synt_1 PF00133.17 KFO95667.1 - 2.2e-168 561.0 0.4 3e-168 560.5 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFO95667.1 - 1.5e-28 99.6 0.8 1.6e-17 63.3 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFO95667.1 - 2.2e-28 98.9 0.2 5.9e-28 97.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 KFO95667.1 - 5.5e-05 22.5 0.0 9.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 KFO95667.1 - 0.00024 20.6 4.4 0.00084 18.9 3.1 2.1 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 KFO95667.1 - 0.00044 19.4 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain RAB3GAP2_C PF14656.1 KFO95668.1 - 9.3e-230 763.7 19.5 1.5e-229 763.0 13.5 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.1 KFO95668.1 - 1.4e-156 521.6 0.0 2.1e-156 521.1 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Pkinase PF00069.20 KFO95669.1 - 2.1e-77 259.8 0.0 3.1e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95669.1 - 4.9e-44 150.3 0.0 7.3e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFO95669.1 - 8.5e-19 66.7 0.0 1.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 KFO95669.1 - 3e-07 29.7 0.0 6e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KFO95669.1 - 0.00016 21.1 0.3 0.00031 20.1 0.2 1.4 1 0 0 1 1 1 1 RIO1 family UBA PF00627.26 KFO95669.1 - 0.00023 20.8 0.0 0.00053 19.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.9 KFO95669.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.6 KFO95669.1 - 0.077 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) APH PF01636.18 KFO95669.1 - 0.15 11.7 0.1 0.53 9.9 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family JmjC PF02373.17 KFO95670.1 - 3.9e-17 62.5 0.1 2.3e-16 60.0 0.1 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.17 KFO95670.1 - 0.00035 20.0 0.1 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Cupin 7tm_4 PF13853.1 KFO95671.1 - 2.6e-59 199.1 9.5 2.6e-59 199.1 6.6 1.7 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO95671.1 - 6.6e-16 58.2 10.2 8.3e-16 57.8 7.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Reticulon PF02453.12 KFO95671.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.5 3 0 0 3 3 3 0 Reticulon Granin PF01271.12 KFO95672.1 - 7.1e-147 490.6 35.4 8.1e-147 490.4 24.5 1.0 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) IF2_N PF04760.10 KFO95672.1 - 0.064 12.9 1.4 2.7 7.7 0.1 3.1 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Clat_adaptor_s PF01217.15 KFO95673.1 - 8e-59 197.4 3.3 8.9e-59 197.2 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-H2C2_2 PF13465.1 KFO95674.1 - 9.1e-51 167.7 51.7 2.5e-11 43.2 0.4 6.5 7 0 0 7 7 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFO95674.1 - 2e-36 122.1 48.9 4.9e-07 29.7 0.2 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO95674.1 - 7.1e-31 104.2 48.3 5.8e-06 26.2 1.8 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO95674.1 - 2.4e-18 65.3 31.1 0.00017 21.3 0.5 6.4 6 1 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO95674.1 - 2.9e-15 55.8 20.3 0.0055 16.8 0.0 6.1 5 1 1 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFO95674.1 - 8.4e-06 25.8 28.8 0.036 14.1 2.7 4.7 2 2 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.1 KFO95674.1 - 3.9e-05 23.6 19.3 0.13 12.2 1.6 5.5 3 2 1 4 4 4 3 CpXC protein RRN7 PF11781.3 KFO95674.1 - 5.5e-05 22.5 13.0 3.2 7.3 0.0 6.0 6 0 0 6 6 6 1 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 KFO95674.1 - 7.2e-05 22.5 21.1 0.14 11.9 0.6 3.8 2 1 1 3 3 3 2 Double zinc ribbon DUF329 PF03884.9 KFO95674.1 - 0.0001 21.7 15.6 1.6 8.3 0.0 6.0 6 0 0 6 6 6 1 Domain of unknown function (DUF329) zf-LYAR PF08790.6 KFO95674.1 - 0.00018 21.1 12.8 5.2 6.8 0.1 6.2 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.2 KFO95674.1 - 0.00044 20.3 20.6 0.46 10.6 0.1 5.5 1 1 5 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 KFO95674.1 - 0.00088 19.2 24.1 1.7 8.7 0.2 6.0 6 0 0 6 6 6 2 zinc-finger Prok-RING_1 PF14446.1 KFO95674.1 - 0.0029 17.2 9.4 20 5.0 0.0 5.8 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.7 KFO95674.1 - 0.0045 16.7 17.0 0.14 11.9 0.9 4.8 3 1 1 4 4 4 1 zinc-ribbons GAGA PF09237.6 KFO95674.1 - 0.0077 15.8 25.4 0.66 9.6 1.7 5.0 2 2 3 5 5 5 2 GAGA factor Zn-ribbon_8 PF09723.5 KFO95674.1 - 0.019 14.9 32.4 2.5 8.1 4.2 5.8 2 2 3 5 5 5 0 Zinc ribbon domain zf-ISL3 PF14690.1 KFO95674.1 - 0.02 14.9 25.6 2.3 8.3 0.1 6.3 6 0 0 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 FYDLN_acid PF09538.5 KFO95674.1 - 0.028 14.9 16.0 11 6.6 0.0 5.6 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) TerY-C PF15616.1 KFO95674.1 - 0.031 14.2 0.5 0.031 14.2 0.3 3.7 1 1 1 3 3 3 0 TerY-C metal binding domain HypA PF01155.14 KFO95674.1 - 0.047 13.3 16.1 14 5.4 0.8 3.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-DNA_Pol PF08996.5 KFO95674.1 - 0.055 12.8 10.5 0.78 9.0 0.2 3.2 1 1 3 4 4 4 0 DNA Polymerase alpha zinc finger zinc_ribbon_5 PF13719.1 KFO95674.1 - 0.06 12.9 29.0 2.6 7.7 0.2 6.1 6 0 0 6 6 6 0 zinc-ribbon domain BolA PF01722.13 KFO95674.1 - 0.11 12.4 0.9 51 3.9 0.0 3.2 3 0 0 3 3 3 0 BolA-like protein zinc_ribbon_4 PF13717.1 KFO95674.1 - 0.22 11.2 28.7 4.6 7.0 0.4 6.1 6 0 0 6 6 6 0 zinc-ribbon domain zf-met2 PF12907.2 KFO95674.1 - 0.33 10.9 16.7 19 5.2 0.0 5.8 6 0 0 6 6 6 0 Zinc-binding zf-HYPF PF07503.7 KFO95674.1 - 0.34 10.3 22.4 11 5.4 0.1 5.9 5 1 0 5 5 5 0 HypF finger C1_4 PF07975.7 KFO95674.1 - 0.49 10.4 18.8 2.6 8.1 0.6 4.8 1 1 4 5 5 5 0 TFIIH C1-like domain zf-IS66 PF13005.2 KFO95674.1 - 0.51 10.3 18.5 31 4.6 0.1 6.0 6 0 0 6 6 6 0 zinc-finger binding domain of transposase IS66 DUF2256 PF10013.4 KFO95674.1 - 0.53 10.0 20.8 0.89 9.3 0.0 5.9 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2256) Rtf2 PF04641.7 KFO95674.1 - 0.77 8.9 5.6 2.6e+02 0.6 3.9 4.0 1 1 0 1 1 1 0 Rtf2 RING-finger XPA_N PF01286.13 KFO95674.1 - 1.1 9.0 12.2 17 5.1 0.1 5.3 6 0 0 6 6 6 0 XPA protein N-terminal zf-AN1 PF01428.11 KFO95674.1 - 1.8 8.4 25.2 6.8 6.6 0.1 6.0 6 0 0 6 6 6 0 AN1-like Zinc finger FYVE PF01363.16 KFO95674.1 - 2.4 8.1 28.1 14 5.6 2.5 5.4 1 1 3 4 4 4 0 FYVE zinc finger LIM PF00412.17 KFO95674.1 - 5 7.2 18.7 23 5.1 1.2 4.7 1 1 4 5 5 4 0 LIM domain Zn_Tnp_IS1595 PF12760.2 KFO95674.1 - 5.4 6.8 36.1 2.2 8.1 4.5 5.5 2 1 4 6 6 6 0 Transposase zinc-ribbon domain LRR_8 PF13855.1 KFO95676.1 - 3.8e-33 113.0 27.2 1.6e-12 46.9 4.2 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFO95676.1 - 1.9e-26 91.1 29.0 2.7e-06 26.8 0.5 7.4 5 2 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO95676.1 - 8.5e-17 58.6 23.0 0.079 13.0 0.1 11.7 10 1 1 11 11 11 4 Leucine Rich Repeat LRR_5 PF13306.1 KFO95676.1 - 1.3e-09 37.7 0.1 0.1 12.3 0.0 3.5 2 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO95676.1 - 5.8e-06 25.6 27.4 11 6.7 0.3 11.1 11 0 0 11 11 11 1 Leucine rich repeat LRR_9 PF14580.1 KFO95676.1 - 1e-05 25.1 8.0 0.016 14.7 0.2 3.3 2 1 1 3 3 3 2 Leucine-rich repeat LRRNT PF01462.13 KFO95676.1 - 0.00014 21.2 2.1 0.00014 21.2 1.5 3.9 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFO95676.1 - 0.00021 21.0 24.9 5.7 7.3 0.2 8.6 8 2 1 9 9 9 2 Leucine Rich repeat fn3 PF00041.16 KFO95676.1 - 0.00047 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.19 KFO95676.1 - 0.0012 18.9 0.1 0.0045 17.1 0.1 2.1 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain Glyco_hydro_59 PF02057.10 KFO95677.1 - 0 1067.3 6.1 0 1067.2 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Laminin_G_3 PF13385.1 KFO95677.1 - 0.0072 16.5 3.0 0.0072 16.5 2.1 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_30 PF02055.11 KFO95677.1 - 0.055 11.6 0.1 0.09 10.9 0.1 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 7tm_1 PF00001.16 KFO95678.1 - 5.1e-47 160.1 21.5 7.6e-47 159.6 14.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFO95678.1 - 1e-05 24.8 19.9 1.5e-05 24.2 10.5 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.4 KFO95678.1 - 0.24 10.4 21.4 0.033 13.2 11.5 1.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Ion_trans_2 PF07885.11 KFO95679.1 - 2.1e-36 123.4 27.7 5.3e-19 67.7 7.8 3.3 3 1 1 4 4 4 2 Ion channel OST3_OST6 PF04756.8 KFO95679.1 - 0.0039 16.7 4.3 0.62 9.6 0.9 2.4 2 0 0 2 2 2 2 OST3 / OST6 family 7tm_1 PF00001.16 KFO95679.1 - 0.004 16.3 0.3 0.004 16.3 0.2 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DmsC PF04976.7 KFO95679.1 - 0.059 12.6 0.2 0.059 12.6 0.1 2.9 1 1 0 2 2 2 0 DMSO reductase anchor subunit (DmsC) DUF2390 PF09523.5 KFO95679.1 - 0.35 11.0 2.2 0.24 11.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Pox_A14 PF05767.7 KFO95679.1 - 0.82 9.6 7.0 3.3 7.7 0.7 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 HSD3 PF15244.1 KFO95680.1 - 2.8e-30 105.9 1.7 3.6e-30 105.5 1.2 1.1 1 0 0 1 1 1 1 Hydroxy-steroid dehydrogenase DUF3940 PF13076.1 KFO95680.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Y_phosphatase PF00102.22 KFO95681.1 - 6.3e-73 244.9 0.0 1.1e-72 244.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_M PF00373.13 KFO95681.1 - 7.8e-22 77.7 3.6 2.6e-21 76.1 2.5 2.0 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFO95681.1 - 8.2e-18 64.2 3.2 8.4e-18 64.2 0.2 2.6 3 0 0 3 3 3 1 FERM N-terminal domain FERM_C PF09380.5 KFO95681.1 - 7.1e-17 61.3 0.3 1.5e-16 60.3 0.2 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain DSPc PF00782.15 KFO95681.1 - 1.2e-05 24.9 0.0 2.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFO95681.1 - 0.0025 18.1 0.0 0.0066 16.7 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family zf-CCCH_2 PF14608.1 KFO95682.1 - 6.5e-16 57.6 56.4 8.8e-07 28.6 3.5 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type PWI PF01480.12 KFO95682.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 PWI domain WD40 PF00400.27 KFO95683.1 - 3.5e-70 229.5 75.6 5.2e-05 22.9 0.0 26.5 29 0 0 29 29 29 18 WD domain, G-beta repeat HELP PF03451.9 KFO95683.1 - 6.9e-32 108.8 0.2 1.6e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 HELP motif Nucleoporin_N PF08801.6 KFO95683.1 - 6e-06 25.2 0.0 1.1 7.8 0.0 4.2 3 1 1 4 4 4 2 Nup133 N terminal like Apc4_WD40 PF12894.2 KFO95683.1 - 0.00033 20.0 0.0 0.074 12.5 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 KFO95683.1 - 0.00042 18.7 10.5 1.4 7.0 0.0 6.4 7 1 0 8 8 8 3 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 KFO95683.1 - 0.0044 15.8 1.9 1.4 7.6 0.0 4.3 5 0 0 5 5 5 1 Coatomer WD associated region Gmad1 PF10647.4 KFO95683.1 - 0.012 14.9 0.0 24 4.2 0.0 4.7 5 0 0 5 5 5 0 Lipoprotein LpqB beta-propeller domain TPR_2 PF07719.12 KFO95684.1 - 3.3e-27 92.1 8.9 0.0034 17.1 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFO95684.1 - 7.8e-25 86.3 15.6 2e-07 30.5 0.4 5.3 3 1 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 KFO95684.1 - 5.6e-23 79.5 15.3 0.00069 19.1 0.2 7.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFO95684.1 - 1.9e-22 78.9 14.2 1.4e-06 28.0 0.2 5.5 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFO95684.1 - 2.5e-17 61.2 6.5 0.03 14.1 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFO95684.1 - 6.9e-17 60.4 3.5 0.004 17.6 0.0 7.6 4 2 4 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFO95684.1 - 1.9e-15 57.0 8.0 8.3e-06 26.3 0.0 5.6 2 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFO95684.1 - 3.1e-14 51.5 8.8 0.0043 16.7 0.0 6.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFO95684.1 - 7.2e-14 51.8 11.9 0.001 19.3 0.0 5.6 4 2 3 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFO95684.1 - 1.1e-08 34.5 11.3 0.047 13.9 0.1 7.8 7 1 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO95684.1 - 4.1e-07 30.0 12.8 0.68 10.5 0.3 7.5 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFO95684.1 - 5.4e-07 29.3 7.7 0.046 13.6 0.5 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO95684.1 - 3.5e-06 27.0 16.4 0.00082 19.4 0.9 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFO95684.1 - 7.6e-05 21.9 0.7 7.6e-05 21.9 0.5 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFO95684.1 - 0.00032 20.4 3.8 14 5.6 0.0 5.0 2 2 4 6 6 6 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KFO95684.1 - 0.00054 19.2 6.3 0.012 14.8 0.4 2.9 1 1 2 3 3 3 2 Coatomer epsilon subunit NARP1 PF12569.3 KFO95684.1 - 0.026 13.2 2.6 0.34 9.6 0.0 2.9 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 DUF2523 PF10734.4 KFO95684.1 - 0.079 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) Tyr-DNA_phospho PF06087.7 KFO95685.1 - 1e-129 433.0 0.0 1.3e-129 432.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KFO95685.1 - 0.05 13.3 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain Ion_trans_2 PF07885.11 KFO95686.1 - 2.4e-20 72.0 22.9 2e-15 56.2 5.7 2.3 2 0 0 2 2 2 2 Ion channel Presenilin PF01080.12 KFO95686.1 - 3.6e-05 22.7 2.3 5.5e-05 22.1 1.6 1.2 1 0 0 1 1 1 1 Presenilin Bap31 PF05529.7 KFO95686.1 - 0.03 13.7 1.3 5.4 6.4 0.0 3.0 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like AAA PF00004.24 KFO95687.1 - 4.3e-43 146.6 0.0 1.1e-42 145.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFO95687.1 - 2.7e-07 30.7 0.1 4.8e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFO95687.1 - 4.5e-07 29.9 0.1 1.4e-06 28.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFO95687.1 - 2.7e-05 23.2 0.0 4.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KFO95687.1 - 3.1e-05 23.7 0.4 0.00029 20.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFO95687.1 - 4.4e-05 23.5 0.0 0.00044 20.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFO95687.1 - 4.8e-05 22.5 0.0 9.3e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFO95687.1 - 0.00045 21.0 0.4 0.0027 18.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFO95687.1 - 0.00057 19.3 0.1 0.0013 18.2 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFO95687.1 - 0.0012 18.2 0.4 0.11 11.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain SKI PF01202.17 KFO95687.1 - 0.0014 18.5 0.0 1.7 8.4 0.0 2.7 2 1 0 2 2 2 2 Shikimate kinase AAA_19 PF13245.1 KFO95687.1 - 0.0014 18.3 0.2 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KFO95687.1 - 0.002 18.0 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFO95687.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFO95687.1 - 0.003 17.5 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFO95687.1 - 0.0043 16.6 0.1 0.073 12.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KFO95687.1 - 0.0046 16.5 0.3 0.03 13.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFO95687.1 - 0.0058 16.7 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase KaiC PF06745.8 KFO95687.1 - 0.0063 15.6 0.1 0.22 10.6 0.0 2.5 2 1 1 3 3 2 1 KaiC AAA_18 PF13238.1 KFO95687.1 - 0.0073 16.6 1.0 0.013 15.7 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KFO95687.1 - 0.0097 15.4 0.7 1 8.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFO95687.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 KFO95687.1 - 0.012 14.3 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 KFO95687.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KFO95687.1 - 0.013 14.7 0.0 0.045 12.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 KFO95687.1 - 0.014 15.0 0.1 0.22 11.1 0.0 2.6 2 1 0 3 3 2 0 NACHT domain NB-ARC PF00931.17 KFO95687.1 - 0.028 13.2 0.0 0.066 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DivIC PF04977.10 KFO95687.1 - 0.064 12.7 0.2 1.9 8.0 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator ABC_tran PF00005.22 KFO95687.1 - 0.082 13.2 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 KFO95687.1 - 0.092 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KFO95687.1 - 0.095 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 KFO95687.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NRDE-2 PF08424.5 KFO95688.1 - 9.7e-108 359.8 6.4 7.5e-107 356.9 1.7 3.9 4 1 1 5 5 5 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KFO95688.1 - 3.1e-08 33.5 0.3 2.4 9.0 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFO95688.1 - 0.006 16.9 0.8 17 5.8 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO95688.1 - 0.03 14.9 0.8 18 6.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat RCSD PF05177.7 KFO95688.1 - 0.072 13.5 16.1 0.2 12.1 11.1 1.7 1 0 0 1 1 1 0 RCSD region TPR_2 PF07719.12 KFO95688.1 - 1.2 9.2 6.4 2.9 8.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat BLVR PF06375.6 KFO95688.1 - 4.5 7.0 20.6 0.54 10.0 9.4 2.5 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) EF-hand_1 PF00036.27 KFO95689.1 - 1.7e-43 142.5 10.0 3.2e-10 38.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFO95689.1 - 8.9e-39 131.4 3.9 1.3e-21 76.4 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFO95689.1 - 5.9e-36 121.8 10.2 4.3e-17 61.4 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFO95689.1 - 1.4e-31 105.5 5.4 1.1e-09 37.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFO95689.1 - 2.9e-28 95.9 5.4 6.2e-07 28.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFO95689.1 - 8.8e-15 54.3 0.1 2.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFO95689.1 - 2.2e-10 40.2 0.4 4.2e-05 23.2 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFO95689.1 - 1.2e-08 34.9 0.0 0.0012 18.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 KFO95689.1 - 6e-07 29.3 1.6 8.2e-06 25.7 0.2 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 KFO95689.1 - 1.3e-06 27.9 0.0 0.18 11.4 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) DUF1103 PF06513.6 KFO95689.1 - 0.00058 19.3 1.4 0.00068 19.0 1.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 KFO95689.1 - 0.0011 18.7 0.5 0.21 11.3 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 KFO95689.1 - 0.0013 18.3 0.1 0.036 13.6 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 KFO95689.1 - 0.015 15.3 1.7 2 8.4 0.1 2.5 3 0 0 3 3 2 0 RNA polymerase Rpb4 DUF3349 PF11829.3 KFO95689.1 - 0.016 15.5 0.4 13 6.2 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Poly_export PF02563.11 KFO95689.1 - 0.049 13.4 0.1 2.8 7.7 0.0 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.5 KFO95689.1 - 0.071 12.8 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 KFO95689.1 - 0.079 12.5 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Toprim_2 PF13155.1 KFO95689.1 - 0.083 13.2 0.9 15 6.0 0.0 2.5 1 1 1 2 2 2 0 Toprim-like Tenui_NCP PF04876.7 KFO95689.1 - 0.098 12.1 0.1 0.96 8.9 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF1880 PF08976.6 KFO95689.1 - 0.12 12.4 0.0 2.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) CMD PF02627.15 KFO95689.1 - 0.19 11.5 1.0 4.9 7.0 0.0 2.8 2 2 2 4 4 3 0 Carboxymuconolactone decarboxylase family VCBS PF13517.1 KFO95689.1 - 2.8 8.3 6.3 60 4.1 0.6 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Pkinase PF00069.20 KFO95690.1 - 3.8e-140 465.4 0.5 3.7e-70 236.0 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95690.1 - 5.1e-68 228.9 0.1 7.4e-34 116.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFO95690.1 - 5.8e-16 58.2 0.0 1.9e-06 27.0 0.0 3.3 3 1 0 3 3 3 2 Kinase-like APH PF01636.18 KFO95690.1 - 2.9e-13 50.1 2.6 6.9e-05 22.6 0.0 4.2 2 2 2 4 4 4 4 Phosphotransferase enzyme family Kdo PF06293.9 KFO95690.1 - 3.9e-13 48.9 0.3 2.3e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KFO95690.1 - 6.5e-09 36.1 1.9 9.3e-09 35.6 0.3 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain RIO1 PF01163.17 KFO95690.1 - 4.5e-07 29.3 1.3 6.6e-05 22.3 0.1 2.5 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KFO95690.1 - 0.00088 18.9 1.0 0.022 14.3 0.0 2.9 3 0 0 3 3 3 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KFO95690.1 - 0.0039 16.5 7.4 0.024 13.9 0.0 3.6 3 1 1 4 4 4 1 PhoP regulatory network protein YrbL DUF2087 PF09860.4 KFO95690.1 - 0.036 13.8 1.1 2.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF4392 PF14336.1 KFO95691.1 - 2.1e-88 295.9 0.0 2.7e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.7 KFO95691.1 - 5.9e-61 204.3 0.1 1e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) SMK-1 PF04802.10 KFO95692.1 - 1.5e-84 282.3 9.2 2.6e-81 271.7 5.3 3.1 3 0 0 3 3 3 2 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 KFO95692.1 - 0.00033 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.13 KFO95692.1 - 0.0044 17.0 0.0 0.02 14.9 0.0 2.2 1 0 0 1 1 1 1 RanBP1 domain C2 PF00168.25 KFO95693.1 - 1.2e-10 41.0 0.0 2.2e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain EGF_CA PF07645.10 KFO95694.1 - 2.3e-46 155.5 91.6 2.1e-11 43.6 5.8 7.4 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.2 KFO95694.1 - 8.4e-32 108.4 59.2 1.2e-10 40.8 2.4 7.6 9 0 0 9 9 9 6 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFO95694.1 - 4.6e-25 87.4 95.4 3e-08 33.6 6.7 8.8 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFO95694.1 - 2.8e-12 46.3 70.8 4.5e-06 26.5 3.6 7.7 7 1 1 8 8 8 5 EGF domain EGF PF00008.22 KFO95694.1 - 2.1e-06 27.5 89.1 0.00022 21.1 5.3 8.5 8 2 0 8 8 8 4 EGF-like domain NADH_oxidored PF08040.6 KFO95696.1 - 3.1e-34 116.3 0.0 3.4e-34 116.2 0.0 1.0 1 0 0 1 1 1 1 MNLL subunit CPSF100_C PF13299.1 KFO95697.1 - 3.2e-44 150.9 1.3 1.3e-43 148.9 0.0 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KFO95697.1 - 2.2e-23 82.5 0.0 5.7e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KFO95697.1 - 2.7e-11 43.1 0.0 5.8e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KFO95697.1 - 9.8e-08 31.8 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Na_Ca_ex PF01699.19 KFO95698.1 - 1.4e-48 164.0 35.0 6.4e-26 90.6 8.8 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 KFO95698.1 - 2.7 7.8 5.6 7.9 6.3 0.5 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF843 PF05814.6 KFO95698.1 - 4.3 7.2 19.2 0.39 10.5 1.4 3.3 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) VPS9 PF02204.13 KFO95699.1 - 1.2e-27 95.9 0.1 1.2e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.18 KFO95699.1 - 1.1e-06 28.9 0.6 2.7e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Peptidase_C13 PF01650.13 KFO95700.1 - 9e-118 392.1 1.5 1.2e-117 391.7 1.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Golgin_A5 PF09787.4 KFO95701.1 - 8e-157 522.8 63.3 8e-157 522.8 43.9 3.3 1 1 2 3 3 3 1 Golgin subfamily A member 5 Myosin_tail_1 PF01576.14 KFO95701.1 - 1.4 6.5 91.1 1.4 6.5 29.6 2.7 1 1 1 2 2 2 0 Myosin tail IncA PF04156.9 KFO95701.1 - 1.7 8.1 101.4 0.14 11.7 12.5 5.3 1 1 4 5 5 5 0 IncA protein Reo_sigmaC PF04582.7 KFO95701.1 - 4.2 6.4 34.9 5 6.2 1.6 4.7 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Ins134_P3_kin PF05770.6 KFO95703.1 - 5.2e-116 386.9 0.3 6.7e-116 386.6 0.2 1.1 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase Rep_fac_C PF08542.6 KFO95703.1 - 0.093 12.7 0.1 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Replication factor C C-terminal domain DUF4583 PF15190.1 KFO95704.1 - 1.4e-74 247.8 2.2 1.6e-74 247.6 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4583) DUF4064 PF13273.1 KFO95704.1 - 0.0021 18.1 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) AA_permease PF00324.16 KFO95704.1 - 0.031 12.6 0.1 0.042 12.1 0.1 1.2 1 0 0 1 1 1 0 Amino acid permease DUF4131 PF13567.1 KFO95704.1 - 0.063 12.6 7.1 0.029 13.7 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) GpcrRhopsn4 PF10192.4 KFO95704.1 - 0.12 11.5 0.1 0.12 11.5 0.1 2.1 2 1 1 3 3 3 0 Rhodopsin-like GPCR transmembrane domain DUF485 PF04341.7 KFO95704.1 - 2.1 8.1 6.7 1.5 8.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF485 PHD PF00628.24 KFO95705.1 - 0.00029 20.4 3.7 0.00029 20.4 2.6 3.3 4 0 0 4 4 4 1 PHD-finger BTB PF00651.26 KFO95706.1 - 3.9e-25 87.9 0.6 6.2e-14 51.9 0.1 3.5 2 1 0 2 2 2 2 BTB/POZ domain BACK PF07707.10 KFO95706.1 - 1.7e-10 40.6 0.2 4.7e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch UNC-79 PF14776.1 KFO95707.1 - 5.3e-11 41.5 0.1 7.3e-11 41.1 0.1 1.2 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 FAM181 PF15238.1 KFO95708.1 - 4.6e-89 299.4 3.5 5.2e-89 299.2 2.4 1.0 1 0 0 1 1 1 1 FAM181 Ank_2 PF12796.2 KFO95709.1 - 4.7e-73 241.5 9.5 7.7e-20 71.0 0.2 5.6 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFO95709.1 - 3e-64 209.7 16.5 9e-07 28.4 0.0 11.3 10 1 1 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 KFO95709.1 - 5.3e-49 163.7 10.9 1.1e-09 38.5 0.0 8.8 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO95709.1 - 2.3e-48 157.3 11.9 9e-05 22.3 0.0 11.6 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 KFO95709.1 - 6e-41 137.5 17.7 2.8e-11 43.2 0.3 10.2 2 1 9 11 11 11 10 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFO95709.1 - 2.7e-13 49.5 4.1 7.3e-13 48.1 2.8 1.8 1 0 0 1 1 1 1 SOCS box Serpin PF00079.15 KFO95710.1 - 1.6e-120 402.6 4.9 1.8e-120 402.4 3.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FSH1 PF03959.8 KFO95710.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2179 PF10035.4 KFO95710.1 - 0.032 13.8 0.0 0.09 12.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Serpin PF00079.15 KFO95711.1 - 7e-105 351.1 1.7 9.6e-105 350.7 1.2 1.2 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFO95712.1 - 1.7e-112 376.2 1.8 1.9e-112 376.1 1.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFO95713.1 - 6.2e-112 374.4 0.2 6.9e-112 374.2 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4198 PF10670.4 KFO95713.1 - 0.023 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) INCENP_N PF12178.3 KFO95713.1 - 0.057 12.9 0.1 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Homeobox PF00046.24 KFO95714.1 - 3.7e-23 80.8 5.5 7.8e-23 79.8 3.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO95714.1 - 0.0035 17.0 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Ribonuclease_3 PF00636.21 KFO95715.1 - 7.9e-75 248.6 0.1 3.3e-48 162.8 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain PAZ PF02170.17 KFO95715.1 - 1.5e-39 134.4 0.1 3.8e-39 133.0 0.1 1.8 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.9 KFO95715.1 - 1.3e-30 104.9 0.0 4.8e-30 103.1 0.0 2.1 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 KFO95715.1 - 1.2e-25 89.9 0.0 3.4e-17 62.5 0.0 4.0 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 KFO95715.1 - 8.5e-18 64.0 0.0 2e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFO95715.1 - 4.6e-13 49.0 0.0 9.3e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFO95715.1 - 2.7e-11 43.6 0.0 8.5e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 KFO95715.1 - 0.00074 20.0 0.0 0.0031 18.0 0.0 2.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif AAA_17 PF13207.1 KFO95715.1 - 0.06 14.1 0.2 17 6.2 0.0 3.4 2 0 0 2 2 2 0 AAA domain CH PF00307.26 KFO95717.1 - 1.8e-31 108.3 0.1 1.6e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFO95717.1 - 2e-06 27.3 0.0 0.0042 16.6 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain Pex14_N PF04695.8 KFO95717.1 - 0.092 12.7 0.5 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region KASH PF10541.4 KFO95718.1 - 1e-23 82.9 7.6 1.8e-23 82.1 5.3 1.4 1 0 0 1 1 1 1 Nuclear envelope localisation domain Spectrin PF00435.16 KFO95718.1 - 2.3e-13 50.3 83.3 6e-07 29.7 3.5 9.1 6 1 3 9 9 9 6 Spectrin repeat YCII PF03795.9 KFO95718.1 - 0.016 15.3 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 YCII-related domain Reo_sigmaC PF04582.7 KFO95718.1 - 0.46 9.5 11.2 0.072 12.2 0.2 3.7 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Glutaredoxin PF00462.19 KFO95719.1 - 7.1e-06 25.9 0.2 5.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF2639 PF11121.3 KFO95719.1 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) 7tm_1 PF00001.16 KFO95720.1 - 1.3e-55 188.3 31.7 1.3e-55 188.3 22.0 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) VPS9 PF02204.13 KFO95720.1 - 1.3 9.0 6.1 0.65 10.0 1.8 2.4 2 1 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain ATG_C PF09333.6 KFO95721.1 - 1.4e-36 124.6 0.1 3.3e-36 123.3 0.1 1.6 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 KFO95721.1 - 5e-13 48.6 0.0 1.4e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 KFO95721.1 - 7.8e-06 25.5 1.2 0.00021 20.8 0.8 2.9 1 1 0 1 1 1 1 Autophagy-related protein 2 CAD motif Folate_carrier PF01770.13 KFO95721.1 - 0.26 9.7 0.2 0.43 9.0 0.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF727 PF05303.7 KFO95722.1 - 2.1e-40 136.8 0.1 2.6e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Glyco_hydro_77 PF02446.12 KFO95722.1 - 0.038 12.5 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase Dpy-30 PF05186.8 KFO95723.1 - 2.9e-12 45.8 0.4 1.2e-11 43.8 0.1 2.3 2 0 0 2 2 2 1 Dpy-30 motif ADK PF00406.17 KFO95723.1 - 1e-11 44.9 0.1 2.7e-06 27.3 0.0 3.1 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KFO95723.1 - 5e-11 43.4 4.1 5e-10 40.2 2.9 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFO95723.1 - 4.9e-10 39.8 6.9 1.5e-09 38.2 0.3 2.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KFO95723.1 - 4.9e-06 26.7 0.0 2.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFO95723.1 - 3.6e-05 23.8 0.2 0.00026 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFO95723.1 - 0.00033 20.8 0.1 0.0053 16.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KFO95723.1 - 0.0013 18.6 0.1 0.0038 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFO95723.1 - 0.0024 17.8 2.1 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFO95723.1 - 0.0046 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 KFO95723.1 - 0.0047 16.5 0.0 0.021 14.4 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KFO95723.1 - 0.0063 16.4 0.6 0.029 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFO95723.1 - 0.0063 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KTI12 PF08433.5 KFO95723.1 - 0.0069 15.6 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 KFO95723.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KFO95723.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.15 KFO95723.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Sigma54_activat PF00158.21 KFO95723.1 - 0.12 11.8 0.0 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 KFO95723.1 - 0.13 12.2 0.0 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase Epimerase PF01370.16 KFO95723.1 - 0.19 11.1 0.0 0.44 9.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PAP_central PF04928.12 KFO95724.1 - 5.2e-109 362.9 0.0 5.2e-109 362.9 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KFO95724.1 - 1.3e-36 125.5 2.0 3.2e-36 124.2 1.4 1.7 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KFO95724.1 - 3e-09 37.0 0.1 7.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.20 KFO95725.1 - 2.3e-17 63.0 0.0 3.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95725.1 - 7e-09 35.1 0.1 2.9e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 KFO95725.1 - 0.0028 16.8 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 KFO95725.1 - 0.03 14.0 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFO95725.1 - 0.085 11.6 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Yae1_N PF09811.4 KFO95727.1 - 6.7e-17 60.7 50.8 1.5e+04 -11.5 35.2 4.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-C2H2 PF00096.21 KFO95728.1 - 6.3e-24 82.8 55.4 1.9e-05 24.7 2.0 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO95728.1 - 4.9e-15 54.9 49.5 2.3e-07 30.7 0.9 8.2 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO95728.1 - 1.5e-11 43.7 51.9 0.01 16.0 0.3 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO95728.1 - 2.8e-10 39.7 49.0 1.3e-06 28.1 0.1 6.9 8 0 0 8 8 8 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFO95728.1 - 0.0023 18.0 2.8 0.0023 18.0 1.9 5.2 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.1 KFO95728.1 - 0.008 16.0 13.0 0.3 10.9 0.4 3.7 3 0 0 3 3 3 2 Zinc-finger GAGA PF09237.6 KFO95728.1 - 0.061 12.9 7.9 1.4 8.5 0.4 3.0 2 1 0 2 2 2 0 GAGA factor DUF4329 PF14220.1 KFO95728.1 - 0.15 12.0 2.5 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) Daxx PF03344.10 KFO95728.1 - 0.45 8.9 14.1 0.68 8.3 9.8 1.2 1 0 0 1 1 1 0 Daxx Family zf-C2H2_jaz PF12171.3 KFO95728.1 - 1.9 8.6 44.6 0.58 10.3 1.4 6.0 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Rubis-subs-bind PF09273.6 KFO95729.1 - 2.3e-35 121.3 0.1 5.7e-35 120.0 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KFO95729.1 - 8.4e-11 42.4 0.0 1.1e-09 38.7 0.0 2.6 3 1 0 3 3 3 1 SET domain Cyclin_N PF00134.18 KFO95730.1 - 4.1e-17 61.9 3.8 2.2e-16 59.5 0.0 2.6 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFO95730.1 - 0.0074 16.2 0.1 0.0074 16.2 0.0 2.4 1 1 1 2 2 2 1 Cyclin, C-terminal domain Rrn6 PF10214.4 KFO95730.1 - 2.2 6.2 15.0 2.7 5.9 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nucleo_P87 PF07267.6 KFO95730.1 - 3.2 6.3 9.0 4.1 5.9 6.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Lin-8 PF03353.10 KFO95730.1 - 4.2 6.5 11.5 6.9 5.8 8.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4557 PF15101.1 KFO95730.1 - 5.2 6.8 14.4 8.6 6.1 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TFIIA PF03153.8 KFO95730.1 - 7.1 6.4 26.2 10 5.8 18.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Borrelia_P83 PF05262.6 KFO95730.1 - 8.8 4.4 10.8 1.1e+02 0.8 0.0 1.9 2 0 0 2 2 2 0 Borrelia P83/100 protein Plasmodium_Vir PF05795.6 KFO95730.1 - 9.3 5.3 5.7 14 4.7 4.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2216 PF10226.4 KFO95731.1 - 1.5e-96 321.5 13.0 1.5e-96 321.5 9.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved proteins (DUF2216) bZIP_1 PF00170.16 KFO95731.1 - 0.0096 15.8 18.1 0.28 11.1 0.8 4.5 3 1 1 4 4 4 2 bZIP transcription factor DUF4577 PF15145.1 KFO95731.1 - 0.064 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) TSC22 PF01166.13 KFO95731.1 - 1.2 9.2 21.9 2.6 8.0 0.4 4.6 4 1 1 5 5 5 0 TSC-22/dip/bun family Shugoshin_N PF07558.6 KFO95731.1 - 8.3 6.2 14.0 0.8 9.4 1.3 3.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.1 KFO95731.1 - 8.9 6.1 12.2 14 5.4 1.1 4.1 4 0 0 4 4 4 0 Sperm tail C-terminal domain Ets PF00178.17 KFO95732.1 - 1e-37 128.0 3.8 1.5e-37 127.5 2.6 1.2 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 KFO95732.1 - 0.068 13.3 0.4 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 HSF-type DNA-binding Pkinase_Tyr PF07714.12 KFO95733.1 - 2.7e-82 275.7 0.0 3.7e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.19 KFO95733.1 - 4.4e-54 181.2 0.2 3.8e-27 94.4 0.0 2.7 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.20 KFO95733.1 - 5.1e-35 120.8 0.0 8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFO95733.1 - 8.4e-20 70.6 3.9 6.7e-06 26.1 0.1 4.5 4 0 0 4 4 4 4 Fibronectin type III domain Furin-like PF00757.15 KFO95733.1 - 2e-18 66.4 16.7 2.4e-17 62.9 11.6 2.3 1 1 0 1 1 1 1 Furin-like cysteine rich region Kinase-like PF14531.1 KFO95733.1 - 0.0013 17.7 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PE_PPE_C PF12484.3 KFO95733.1 - 0.012 16.4 1.2 0.04 14.8 0.8 1.8 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal TMEM154 PF15102.1 KFO95733.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family PRCC PF10253.4 KFO95734.1 - 7.2e-27 95.2 20.9 2.2e-25 90.4 14.5 2.2 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting DUF1840 PF08895.6 KFO95734.1 - 0.19 11.7 2.2 0.69 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Trypsin PF00089.21 KFO95735.1 - 2.1e-61 207.3 0.1 2.3e-61 207.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFO95735.1 - 0.00051 19.4 0.1 0.001 18.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFO95735.1 - 0.0022 17.9 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KFO95736.1 - 1.8e-68 230.4 0.8 2e-68 230.2 0.5 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFO95736.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFO95736.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.21 KFO95738.1 - 9.2e-12 45.0 0.9 9.7e-12 44.9 0.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 KFO95739.1 - 2.7e-73 246.1 2.0 3.1e-73 246.0 1.4 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFO95739.1 - 2.5e-05 23.7 0.2 5.3e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFO95739.1 - 0.017 15.0 0.0 0.041 13.8 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.21 KFO95740.1 - 1.9e-15 57.0 0.7 2e-15 56.9 0.5 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.21 KFO95741.1 - 5e-16 58.9 0.7 5.4e-16 58.8 0.5 1.0 1 0 0 1 1 1 1 Trypsin SspN PF08177.6 KFO95742.1 - 0.54 10.0 2.9 19 5.0 0.1 3.6 2 1 0 2 2 2 0 Small acid-soluble spore protein N family AMP-binding PF00501.23 KFO95743.1 - 5.2e-47 160.1 0.0 7.4e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3939 PF13075.1 KFO95743.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) BRI3BP PF14965.1 KFO95744.1 - 9.9e-83 275.8 0.5 1.1e-82 275.6 0.3 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 ubiquitin PF00240.18 KFO95745.1 - 3.2e-106 346.8 11.8 7.9e-35 118.0 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 KFO95745.1 - 8.2e-62 204.8 10.8 6.8e-20 70.5 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFO95745.1 - 1.6e-21 76.3 3.6 2.4e-05 24.5 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFO95745.1 - 1.4e-15 57.3 0.0 0.0018 18.0 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KFO95745.1 - 1.4e-11 44.2 0.9 0.048 13.5 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFO95745.1 - 5.3e-10 39.3 0.2 0.16 12.2 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 KFO95745.1 - 4.8e-09 36.0 1.1 0.24 11.3 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF2870 PF11069.3 KFO95745.1 - 7e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 KFO95745.1 - 7.9e-06 25.5 0.6 3.6 7.3 0.0 3.3 3 0 0 3 3 3 3 FlgD Ig-like domain USP7_C2 PF14533.1 KFO95745.1 - 8.1e-05 22.1 1.6 4.2 6.7 0.0 3.1 1 1 0 3 3 3 3 Ubiquitin-specific protease C-terminal CTDII PF01556.13 KFO95745.1 - 0.0024 17.7 8.9 1.7 8.5 0.2 3.3 1 1 2 3 3 3 2 DnaJ C terminal domain FERM_N PF09379.5 KFO95745.1 - 0.0032 17.4 3.6 27 4.9 0.1 4.7 3 3 0 3 3 3 0 FERM N-terminal domain Plexin_cytopl PF08337.7 KFO95745.1 - 0.0033 15.8 5.5 3.7 5.7 0.1 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain YfmQ PF10787.4 KFO95745.1 - 0.015 14.6 0.2 33 3.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein from bacillus cereus group GABP-alpha PF11620.3 KFO95745.1 - 0.017 15.0 1.3 37 4.3 0.0 3.0 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 KFO95745.1 - 0.02 14.2 0.1 13 5.0 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase DUF3781 PF12636.2 KFO95745.1 - 0.32 10.9 1.9 1.1e+02 2.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) YajC PF02699.10 KFO95745.1 - 0.61 9.8 4.1 37 4.0 0.0 3.1 3 0 0 3 3 3 0 Preprotein translocase subunit Sec_GG PF07549.9 KFO95745.1 - 1.9 7.8 5.5 1.7e+02 1.7 0.0 4.6 5 0 0 5 5 5 0 SecD/SecF GG Motif CD36 PF01130.16 KFO95747.1 - 1.9e-138 461.7 1.5 2.1e-138 461.5 1.1 1.0 1 0 0 1 1 1 1 CD36 family DUF3068 PF11271.3 KFO95747.1 - 0.028 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) FAM101 PF15068.1 KFO95749.1 - 1e-96 322.3 0.0 1.1e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 FAM101 family CCDC92 PF14916.1 KFO95750.1 - 3.7e-23 80.8 9.4 1.8e-22 78.6 1.6 2.7 1 1 1 2 2 2 1 Coiled-coil domain of unknown function Sigma54_DBD PF04552.8 KFO95750.1 - 0.0034 16.9 2.9 0.0064 16.0 2.0 1.4 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Angiomotin_C PF12240.3 KFO95750.1 - 0.0099 15.3 7.5 0.0099 15.3 5.2 1.9 1 1 0 2 2 2 1 Angiomotin C terminal DUF4407 PF14362.1 KFO95750.1 - 0.027 13.4 4.3 0.048 12.6 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rootletin PF15035.1 KFO95750.1 - 0.059 13.3 16.7 0.36 10.7 11.0 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 KFO95750.1 - 0.096 12.5 25.5 0.43 10.4 0.4 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med30 PF11315.3 KFO95750.1 - 0.099 12.7 6.7 0.04 14.0 2.7 1.7 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF3584 PF12128.3 KFO95750.1 - 0.15 9.3 13.4 0.19 9.0 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2775 PF10950.3 KFO95750.1 - 0.22 11.7 2.7 4.8 7.4 1.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2775) V_ATPase_I PF01496.14 KFO95750.1 - 0.34 8.7 9.3 0.44 8.3 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NYD-SP28 PF14772.1 KFO95750.1 - 0.43 10.6 12.1 0.5 10.4 5.2 2.4 2 0 0 2 2 2 0 Sperm tail IncA PF04156.9 KFO95750.1 - 0.49 9.9 23.5 4.7 6.7 1.1 3.1 1 1 1 3 3 3 0 IncA protein Atg14 PF10186.4 KFO95750.1 - 0.65 8.8 15.4 0.75 8.6 9.3 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KFO95750.1 - 0.7 8.8 18.3 0.45 9.5 11.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF812 PF05667.6 KFO95750.1 - 0.88 8.0 19.0 0.02 13.3 5.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF812) FlxA PF14282.1 KFO95750.1 - 1 9.3 17.3 1 9.3 1.3 3.3 1 1 2 3 3 3 0 FlxA-like protein Reo_sigmaC PF04582.7 KFO95750.1 - 1.4 8.0 7.7 2.8 7.0 3.7 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 KFO95750.1 - 1.4 8.7 20.2 17 5.1 14.0 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HrpB7 PF09486.5 KFO95750.1 - 1.8 8.4 12.3 10 6.0 0.1 3.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Orthopox_A5L PF06193.6 KFO95750.1 - 2 8.3 8.6 2.9 7.7 5.6 1.5 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like bZIP_1 PF00170.16 KFO95750.1 - 3 7.8 20.8 2 8.4 4.8 3.4 2 1 1 3 3 3 0 bZIP transcription factor DUF869 PF05911.6 KFO95750.1 - 3.1 5.9 21.6 1.2 7.2 10.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) ADIP PF11559.3 KFO95750.1 - 4.2 7.2 22.0 8.9 6.1 2.7 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 KFO95750.1 - 4.7 7.0 8.3 1.9 8.3 1.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.10 KFO95750.1 - 5.2 6.6 11.5 2.1 7.8 3.3 3.1 2 2 0 3 3 3 0 Septum formation initiator Allexi_40kDa PF05549.6 KFO95750.1 - 5.4 6.2 8.8 5.4 6.2 2.4 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein MSG PF02349.10 KFO95750.1 - 6.5 6.8 11.5 17 5.4 7.8 1.9 1 1 0 1 1 1 0 Major surface glycoprotein AAA_13 PF13166.1 KFO95750.1 - 6.7 5.0 14.3 13 4.0 9.9 1.4 1 1 0 1 1 1 0 AAA domain GAS PF13851.1 KFO95750.1 - 7 5.7 22.4 5.7 6.0 10.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 KFO95751.1 - 5.8e-280 930.4 6.4 6.6e-280 930.3 4.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 KFO95751.1 - 0.014 15.2 5.2 0.026 14.3 1.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 KFO95751.1 - 0.23 10.9 3.5 0.42 10.1 2.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family IFP_35_N PF07334.8 KFO95751.1 - 1.3 9.0 4.4 2.7 7.9 3.1 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1619 PF07773.6 KFO95752.1 - 4.7e-55 187.4 1.6 7.3e-53 180.2 1.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) Tfb4 PF03850.9 KFO95753.1 - 4.1e-97 324.7 0.5 4.9e-97 324.4 0.4 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Baculo_IE-1 PF05290.6 KFO95753.1 - 1.7 8.3 8.3 0.57 9.9 3.3 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) IF-2B PF01008.12 KFO95754.1 - 4.3e-77 258.8 0.0 4.9e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family SPC12 PF06645.8 KFO95754.1 - 0.0087 15.8 0.1 0.058 13.1 0.0 2.1 2 0 0 2 2 2 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DEAD PF00270.24 KFO95755.1 - 8.5e-40 136.0 0.0 8.5e-40 136.0 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFO95755.1 - 5.8e-21 73.8 0.2 1.6e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFO95755.1 - 1.1e-19 70.0 0.0 2.9e-18 65.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4137 PF13593.1 KFO95755.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.1 KFO95755.1 - 0.018 15.1 0.3 0.061 13.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain SHOCT PF09851.4 KFO95755.1 - 0.024 14.1 0.3 0.024 14.1 0.2 2.9 3 0 0 3 3 3 0 Short C-terminal domain EMP24_GP25L PF01105.19 KFO95756.1 - 3.1e-39 134.5 0.1 3.7e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RILP PF11461.3 KFO95757.1 - 2.9e-24 84.9 2.1 2.9e-24 84.9 1.5 2.6 2 1 0 2 2 2 1 Rab interacting lysosomal protein Jnk-SapK_ap_N PF09744.4 KFO95757.1 - 5.7e-14 52.4 6.0 5.7e-14 52.4 4.2 3.3 2 1 2 4 4 4 1 JNK_SAPK-associated protein-1 YflT PF11181.3 KFO95757.1 - 0.0053 16.8 4.0 0.0062 16.6 1.4 2.2 2 1 0 2 2 2 1 Heat induced stress protein YflT FliT PF05400.8 KFO95757.1 - 0.018 15.4 3.3 0.018 15.4 2.3 3.3 1 1 2 3 3 2 0 Flagellar protein FliT UBA_e1_C PF09358.5 KFO95757.1 - 1.2 9.2 4.4 0.55 10.3 0.1 2.5 2 2 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain DUF3450 PF11932.3 KFO95757.1 - 1.3 8.2 16.2 5 6.3 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) YlqD PF11068.3 KFO95757.1 - 2.1 8.4 20.0 5.2 7.1 7.1 2.7 1 1 1 2 2 2 0 YlqD protein Spectrin PF00435.16 KFO95757.1 - 2.2 8.6 19.9 0.27 11.5 5.6 3.0 2 1 1 3 3 3 0 Spectrin repeat DUF4407 PF14362.1 KFO95757.1 - 2.3 7.0 16.3 5.6 5.8 7.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) AATF-Che1 PF13339.1 KFO95757.1 - 2.4 8.3 17.1 4.4 7.4 1.6 3.5 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor HrpB7 PF09486.5 KFO95757.1 - 2.6 7.9 12.0 1.7 8.5 0.2 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) IncA PF04156.9 KFO95757.1 - 8.6 5.9 32.0 8 6.0 9.1 2.2 1 1 1 2 2 2 0 IncA protein RRM_1 PF00076.17 KFO95758.1 - 9.2e-18 63.6 0.1 1.4e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95758.1 - 2.1e-11 43.6 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95758.1 - 8.1e-07 28.7 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 KFO95759.1 - 2.7e-19 70.0 0.2 2.7e-19 70.0 0.1 2.5 2 2 0 2 2 2 1 SET domain CDK2AP PF09806.4 KFO95760.1 - 5.5e-22 78.9 0.0 6.1e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein RF-1 PF00472.15 KFO95761.1 - 3.5e-26 91.2 3.9 4e-26 91.0 2.7 1.1 1 0 0 1 1 1 1 RF-1 domain DUF620 PF04788.7 KFO95761.1 - 0.096 11.8 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF620) UPF0300 PF08594.5 KFO95761.1 - 0.13 11.1 0.6 0.16 10.8 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) DNA_pol_phi PF04931.8 KFO95761.1 - 2.2 5.9 8.8 9.1 3.9 6.9 1.4 2 0 0 2 2 2 0 DNA polymerase phi Laminin_I PF06008.9 KFO95762.1 - 0.00034 20.0 23.0 0.0015 17.9 7.5 2.8 1 1 1 2 2 2 2 Laminin Domain I Cast PF10174.4 KFO95762.1 - 0.0014 16.7 30.5 0.0014 16.7 21.2 1.8 2 0 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone Tropomyosin PF00261.15 KFO95762.1 - 0.002 17.2 31.3 0.17 10.9 13.8 3.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFO95762.1 - 0.0028 17.4 36.2 0.24 11.2 14.7 3.5 1 1 1 2 2 2 2 Tropomyosin like Tup_N PF08581.5 KFO95762.1 - 0.046 13.8 0.4 0.046 13.8 0.3 4.5 3 1 1 4 4 4 0 Tup N-terminal RPW8 PF05659.6 KFO95762.1 - 0.097 12.2 8.3 0.1 12.1 3.6 2.6 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Laminin_II PF06009.7 KFO95762.1 - 0.19 11.4 20.9 0.19 11.4 2.9 3.3 1 1 2 3 3 3 0 Laminin Domain II Hemerythrin PF01814.18 KFO95762.1 - 0.21 11.7 7.7 0.61 10.2 0.2 3.0 1 1 0 2 2 2 0 Hemerythrin HHE cation binding domain IncA PF04156.9 KFO95762.1 - 0.32 10.5 36.3 0.32 10.5 10.8 3.5 2 1 1 3 3 3 0 IncA protein BLOC1_2 PF10046.4 KFO95762.1 - 0.77 9.9 22.2 8.8 6.5 5.7 3.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3810 PF12725.2 KFO95762.1 - 1 8.2 10.5 1.2 7.9 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Med9 PF07544.8 KFO95762.1 - 1.7 8.4 17.2 2.1 8.1 0.4 5.0 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.17 KFO95762.1 - 4.6 7.2 29.3 1.8 8.6 9.0 4.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.1 KFO95762.1 - 4.6 6.6 45.6 0.034 13.5 11.5 3.2 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.7 KFO95762.1 - 5.9 6.6 13.7 0.92 9.3 2.3 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 KFO95762.1 - 8.2 6.3 8.0 27 4.7 0.2 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) SR-25 PF10500.4 KFO95763.1 - 5.1e-72 241.9 83.1 3.4e-71 239.2 20.8 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein zf-H2C2 PF09337.5 KFO95765.1 - 2.6e-05 23.5 1.2 5.1e-05 22.6 0.8 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve PF00665.21 KFO95765.1 - 0.0099 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF2348 PF09807.4 KFO95765.1 - 0.049 12.7 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) ABC_membrane PF00664.18 KFO95766.1 - 9.5e-54 182.6 17.1 2.1e-53 181.5 11.9 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFO95766.1 - 2.4e-34 118.5 0.0 4.9e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KFO95766.1 - 7.5e-11 41.6 0.2 2.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFO95766.1 - 4.8e-06 26.6 0.0 9.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFO95766.1 - 2.6e-05 23.4 0.0 7.1e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KFO95766.1 - 0.00015 21.7 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_membrane_3 PF13748.1 KFO95766.1 - 0.00017 20.6 4.6 0.00038 19.5 3.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.1 KFO95766.1 - 0.0005 20.2 0.0 0.0019 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFO95766.1 - 0.0011 18.4 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KFO95766.1 - 0.017 15.0 0.3 0.13 12.1 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4191 PF13829.1 KFO95766.1 - 0.083 12.0 0.1 0.083 12.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) AAA_23 PF13476.1 KFO95766.1 - 0.17 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mod_r PF07200.8 KFO95767.1 - 1.4e-40 138.6 8.7 1.6e-40 138.4 6.0 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Surf_Ag_VNR PF07244.10 KFO95767.1 - 0.025 14.9 0.2 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat Muted PF14942.1 KFO95767.1 - 0.11 12.3 2.4 0.37 10.6 0.0 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein zf-C4H2 PF10146.4 KFO95767.1 - 0.16 11.9 6.2 1.1 9.2 4.3 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 KFO95767.1 - 4.1 6.9 8.0 4.9 6.7 1.9 2.0 1 1 1 2 2 2 0 IncA protein PROL5-SMR PF15621.1 KFO95767.1 - 4.2 7.8 18.5 6.7 7.1 12.8 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family ANTH PF07651.11 KFO95768.1 - 1.5e-75 253.5 0.1 1.5e-75 253.5 0.1 2.8 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KFO95768.1 - 4.2e-26 91.7 1.3 4.2e-26 91.7 0.9 5.2 3 1 2 5 5 5 1 I/LWEQ domain ENTH PF01417.15 KFO95768.1 - 1.5e-07 31.3 0.0 5.8e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 ENTH domain DUF3584 PF12128.3 KFO95768.1 - 0.88 6.8 60.4 0.036 11.4 35.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) UFD1 PF03152.9 KFO95769.1 - 0.017 14.2 5.5 0.047 12.8 0.2 2.2 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 DUF2745 PF10922.3 KFO95769.1 - 0.02 14.8 1.7 0.48 10.3 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2745) DUF3347 PF11827.3 KFO95769.1 - 0.037 14.0 23.0 0.11 12.4 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Lact_bio_phlase PF09508.5 KFO95769.1 - 0.1 10.2 0.3 0.15 9.7 0.2 1.2 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase Retrotrans_gag PF03732.12 KFO95769.1 - 0.65 10.0 16.1 1.6 8.8 1.6 3.9 2 1 1 4 4 4 0 Retrotransposon gag protein DUF1664 PF07889.7 KFO95769.1 - 0.9 9.3 21.7 0.17 11.6 3.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4201 PF13870.1 KFO95769.1 - 6.6 6.1 49.0 1.9 7.9 10.9 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Caenor_Her-1 PF09232.5 KFO95769.1 - 9.8 6.2 10.0 12 6.0 2.2 2.2 1 1 1 2 2 2 0 Caenorhabditis elegans Her-1 SUI1 PF01253.17 KFO95770.1 - 3e-17 62.1 0.2 5.2e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 ATP_bind_1 PF03029.12 KFO95771.1 - 5.1e-89 297.9 0.4 5.8e-89 297.7 0.3 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KFO95771.1 - 0.016 13.9 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 ArgK protein CbiA PF01656.18 KFO95771.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain P21-Arc PF04062.9 KFO95772.1 - 5.1e-81 270.6 0.2 5.6e-81 270.4 0.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit TPR_11 PF13414.1 KFO95773.1 - 4.2e-18 64.7 7.9 0.00086 18.9 0.0 6.8 5 2 1 6 6 6 5 TPR repeat TPR_19 PF14559.1 KFO95773.1 - 3.2e-14 52.9 9.9 8.3e-05 22.8 0.0 6.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFO95773.1 - 2.5e-13 50.2 0.3 0.00053 20.5 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFO95773.1 - 4.8e-13 47.9 14.3 0.052 13.4 0.0 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFO95773.1 - 6.8e-13 48.0 5.0 0.19 12.4 0.0 8.1 5 3 3 9 9 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO95773.1 - 7.2e-08 32.4 14.1 0.087 12.9 0.4 5.8 4 3 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFO95773.1 - 1.8e-06 27.3 14.5 0.076 12.6 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO95773.1 - 3.2e-06 26.9 13.8 4.4 7.2 0.4 7.2 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFO95773.1 - 8.9e-06 25.1 4.3 0.5 10.2 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 KFO95773.1 - 2.3e-05 24.3 4.7 0.00017 21.5 0.7 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO95773.1 - 0.00013 22.1 9.1 1.8 9.2 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFO95773.1 - 0.00016 21.1 3.6 4.7 7.2 0.0 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFO95773.1 - 0.0018 18.3 7.5 31 5.0 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.5 KFO95773.1 - 0.003 16.3 3.1 0.27 9.9 0.1 2.5 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) FeoC PF09012.5 KFO95773.1 - 0.019 14.6 0.2 0.066 12.9 0.1 1.9 1 0 0 1 1 1 0 FeoC like transcriptional regulator TPR_20 PF14561.1 KFO95773.1 - 0.032 14.3 5.6 4.1 7.5 0.2 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 KFO95774.1 - 1.3e-68 230.4 2.6 1.9e-66 223.3 1.1 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFO95774.1 - 5.9e-45 153.0 2.6 5.9e-45 153.0 1.8 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFO95774.1 - 2.6e-29 103.1 0.2 5.6e-23 82.4 0.0 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFO95774.1 - 1e-22 79.8 0.4 2.3e-22 78.7 0.3 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFO95774.1 - 5.1e-18 64.2 1.2 3.9e-17 61.4 0.1 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFO95774.1 - 2e-14 54.1 0.7 9.6e-14 51.9 0.5 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFO95774.1 - 2.2e-05 24.1 0.6 2.2e-05 24.1 0.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF948 PF06103.6 KFO95775.1 - 0.055 13.3 0.3 0.055 13.3 0.2 5.0 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) P2X_receptor PF00864.14 KFO95777.1 - 1.4e-171 570.3 3.5 1.5e-171 570.1 2.4 1.0 1 0 0 1 1 1 1 ATP P2X receptor Pkinase PF00069.20 KFO95778.1 - 4.1e-66 222.7 0.0 6.1e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95778.1 - 3.2e-34 118.1 0.0 5.7e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFO95778.1 - 1.3e-09 37.4 0.0 2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFO95778.1 - 0.011 15.0 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KFO95778.1 - 0.026 14.2 0.2 0.57 9.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFO95778.1 - 0.045 12.5 0.1 1.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Seadornavirus VP7 Apc5 PF12862.2 KFO95779.1 - 3.1e-31 107.0 2.4 3.1e-31 107.0 1.7 4.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 KFO95779.1 - 6.1e-08 32.5 10.6 0.0037 17.1 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFO95779.1 - 1.8e-06 28.1 7.2 0.013 15.8 0.1 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO95779.1 - 3.1e-05 24.2 9.6 0.19 12.4 0.4 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFO95779.1 - 4.9e-05 22.8 7.3 0.041 13.6 0.5 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFO95779.1 - 0.00031 20.5 7.1 0.29 11.1 1.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFO95779.1 - 0.039 13.8 13.6 6.9 6.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFO95779.1 - 0.72 9.5 7.4 1.8 8.3 0.9 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFO95779.1 - 1.3 8.7 11.4 0.37 10.4 0.3 4.5 4 1 0 4 4 4 0 TPR repeat TPR_4 PF07721.9 KFO95779.1 - 1.8 9.2 7.8 1 9.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFO95779.1 - 8.4 7.1 10.2 42 4.9 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat zf-CXXC PF02008.15 KFO95780.1 - 1.2e-14 53.8 21.5 1.2e-14 53.8 14.9 3.0 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.28 KFO95780.1 - 2.4e-13 49.3 6.9 1.3e-12 46.9 1.1 2.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFO95780.1 - 4.2e-09 35.9 6.1 1.2e-08 34.5 4.2 1.8 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.1 KFO95780.1 - 3.1e-06 26.8 0.1 3.1e-06 26.8 0.1 2.4 3 1 0 3 3 3 1 Cupin-like domain LRR_8 PF13855.1 KFO95780.1 - 1.1e-05 25.0 7.5 0.25 11.1 0.2 4.4 4 0 0 4 4 4 3 Leucine rich repeat JmjC PF02373.17 KFO95780.1 - 5.4e-05 23.4 0.3 5.4e-05 23.4 0.2 3.5 4 1 0 4 4 4 1 JmjC domain, hydroxylase LRR_6 PF13516.1 KFO95780.1 - 0.00035 20.3 14.9 0.92 9.7 0.0 7.0 8 1 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 KFO95780.1 - 5.4 7.4 12.3 28 5.2 0.1 6.1 6 1 0 6 6 6 0 Leucine Rich Repeat Orai-1 PF07856.7 KFO95781.1 - 1e-59 201.0 5.3 1.1e-59 200.9 3.7 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity PEN-2 PF10251.4 KFO95781.1 - 0.017 15.3 0.4 0.052 13.7 0.1 1.8 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase KASH PF10541.4 KFO95781.1 - 0.02 14.7 0.7 0.55 10.1 0.1 2.3 2 0 0 2 2 2 0 Nuclear envelope localisation domain m04gp34like PF12216.3 KFO95781.1 - 0.034 13.5 0.4 0.42 9.9 0.1 2.0 1 1 1 2 2 2 0 Immune evasion protein 7TM_GPCR_Str PF10326.4 KFO95781.1 - 0.043 12.9 5.0 1.2 8.1 0.3 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF4328 PF14219.1 KFO95781.1 - 0.12 11.6 1.8 2 7.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) DUF2207 PF09972.4 KFO95781.1 - 0.13 10.8 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DctQ PF04290.7 KFO95781.1 - 0.16 11.7 3.5 0.09 12.5 0.5 1.8 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component MscS_TM PF12794.2 KFO95781.1 - 0.19 10.3 4.1 0.042 12.4 0.7 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Neurensin PF14927.1 KFO95781.1 - 0.22 10.8 3.0 1.1 8.6 0.9 2.2 1 1 1 2 2 2 0 Neurensin Ycf4 PF02392.11 KFO95781.1 - 0.28 10.4 1.6 12 5.1 0.2 2.3 2 1 0 2 2 2 0 Ycf4 MgtE PF01769.11 KFO95781.1 - 0.91 9.8 5.1 0.24 11.6 0.4 2.0 1 1 1 2 2 2 0 Divalent cation transporter MORN PF02493.15 KFO95782.1 - 5.6e-29 98.1 40.9 4.7e-05 22.8 0.1 6.7 7 0 0 7 7 7 6 MORN repeat TMPIT PF07851.8 KFO95783.1 - 7.9e-159 528.0 17.6 8.7e-159 527.9 12.2 1.0 1 0 0 1 1 1 1 TMPIT-like protein N-SET PF11764.3 KFO95784.1 - 1.5e-37 129.0 0.0 1.5e-37 129.0 0.0 3.1 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 KFO95784.1 - 6.1e-22 78.6 1.8 6.1e-22 78.6 1.2 4.0 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.17 KFO95784.1 - 6.8e-09 35.2 0.1 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95784.1 - 3.1e-06 27.0 0.1 6.4e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95784.1 - 3.4e-06 26.8 0.0 6.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyoxalase PF00903.20 KFO95785.1 - 1.1e-21 77.0 0.5 1e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFO95785.1 - 4.9e-13 49.0 0.1 1.8e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFO95785.1 - 3e-07 31.0 0.0 3.7e-05 24.2 0.0 2.6 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KFO95785.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 KFO95785.1 - 0.0099 15.8 0.0 2.8 7.8 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain PDZ_2 PF13180.1 KFO95786.1 - 1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KFO95786.1 - 3.6e-07 30.2 0.1 9.3e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 KFO95786.1 - 0.00051 20.0 0.0 0.00071 19.5 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain TraF_2 PF13729.1 KFO95786.1 - 0.056 12.2 0.0 0.072 11.8 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Rootletin PF15035.1 KFO95786.1 - 0.43 10.5 4.5 0.17 11.8 1.4 1.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion WD40 PF00400.27 KFO95787.1 - 6e-19 67.1 12.0 0.013 15.3 0.0 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat eIF2A PF08662.6 KFO95787.1 - 0.00014 21.6 1.1 0.021 14.5 0.0 3.8 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A EF-hand_7 PF13499.1 KFO95787.1 - 0.053 13.6 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair UPF0154 PF03672.8 KFO95787.1 - 0.21 11.1 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) BCL_N PF04714.8 KFO95788.1 - 7.9e-09 34.9 1.5 1.8e-08 33.7 0.6 1.9 2 0 0 2 2 2 1 BCL7, N-terminal conserver region DUF966 PF06136.8 KFO95788.1 - 2.7 7.3 22.9 3.4 7.0 15.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) HLH PF00010.21 KFO95789.1 - 5.8e-06 25.9 1.3 5.8e-06 25.9 0.9 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 KFO95789.1 - 0.019 15.2 1.5 0.045 14.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 KFO95789.1 - 0.033 13.6 2.1 0.063 12.7 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Troponin PF00992.15 KFO95789.1 - 0.11 12.6 3.0 0.23 11.5 2.0 1.5 1 1 0 1 1 1 0 Troponin LRR_4 PF12799.2 KFO95790.1 - 1.2e-11 43.9 13.4 1.3e-06 27.9 3.0 3.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO95790.1 - 7.1e-10 38.4 11.1 5.5e-05 22.8 0.8 3.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KFO95790.1 - 2.8e-07 30.2 1.2 7.2e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 KFO95790.1 - 0.00027 20.5 13.3 0.98 9.7 1.2 5.6 5 0 0 5 5 5 1 Leucine Rich Repeat FNIP PF05725.7 KFO95790.1 - 0.08 12.9 0.3 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 FNIP Repeat LRR_6 PF13516.1 KFO95790.1 - 0.1 12.6 14.9 0.087 12.9 1.0 5.0 3 2 2 5 5 5 0 Leucine Rich repeat Smac_DIABLO PF09057.5 KFO95791.1 - 3.3e-85 284.9 1.6 3.7e-85 284.8 1.1 1.0 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases DUF1268 PF06896.6 KFO95791.1 - 0.094 13.0 0.3 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1268) Sec1 PF00995.18 KFO95792.1 - 3.4e-124 415.5 0.0 3.8e-124 415.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CAP_GLY PF01302.20 KFO95793.1 - 1.2e-47 159.5 3.3 4.3e-24 83.9 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain IncA PF04156.9 KFO95793.1 - 0.0013 18.3 32.9 0.0013 18.3 22.8 10.4 1 1 8 10 10 10 4 IncA protein zf-CCHC_4 PF14392.1 KFO95793.1 - 2.6 7.8 9.5 10 5.8 0.2 2.8 2 0 0 2 2 2 0 Zinc knuckle PSP PF04046.11 KFO95794.1 - 2.8e-18 65.0 0.2 6.5e-18 63.8 0.1 1.7 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.18 KFO95794.1 - 3e-06 26.8 3.9 5.2e-06 26.1 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KFO95794.1 - 0.033 13.8 2.1 0.073 12.7 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle SMAP PF15477.1 KFO95795.1 - 4.3e-13 49.3 0.9 4.3e-13 49.3 0.6 4.4 4 2 0 4 4 4 1 Small acidic protein family DUF1777 PF08648.7 KFO95795.1 - 3.2e-09 36.7 30.2 3.2e-09 36.7 20.9 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF1777) Pap_E4 PF02711.9 KFO95795.1 - 0.17 12.7 0.2 0.17 12.7 0.1 5.5 1 1 3 4 4 4 0 E4 protein Rod_C PF10493.4 KFO95796.1 - 7.8e-225 747.3 7.9 7.8e-225 747.3 5.5 1.8 2 0 0 2 2 2 1 Rough deal protein C-terminal region APG12 PF04110.8 KFO95796.1 - 0.19 11.9 3.7 28 4.9 0.0 4.8 6 0 0 6 6 6 0 Ubiquitin-like autophagy protein Apg12 Metallophos_2 PF12850.2 KFO95797.1 - 4.5e-21 75.3 0.1 5.1e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFO95797.1 - 2.2e-07 30.5 1.9 0.00031 20.2 1.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SpoIIE PF07228.7 KFO95798.1 - 3e-15 56.4 0.0 4.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFO95798.1 - 8e-07 28.6 0.1 2.3e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KFO95798.1 - 2.3e-05 23.9 0.2 0.0054 16.1 0.1 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C DUF1619 PF07773.6 KFO95799.1 - 1.4e-64 218.7 5.8 3.9e-64 217.2 2.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) CryBP1 PF07029.6 KFO95799.1 - 0.015 15.0 0.4 0.031 14.0 0.2 1.4 1 0 0 1 1 1 0 CryBP1 protein Ion_trans PF00520.26 KFO95800.1 - 6.7e-05 22.2 7.5 6.7e-05 22.2 5.2 1.5 2 0 0 2 2 2 1 Ion transport protein IncA PF04156.9 KFO95800.1 - 0.0012 18.5 1.1 0.0021 17.6 0.8 1.4 1 0 0 1 1 1 1 IncA protein TMF_DNA_bd PF12329.3 KFO95800.1 - 0.015 15.0 4.9 0.025 14.3 3.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Kinetocho_Slk19 PF12709.2 KFO95800.1 - 0.019 14.9 0.5 0.036 14.1 0.4 1.4 1 0 0 1 1 1 0 Central kinetochore-associated XLF PF09302.6 KFO95800.1 - 0.027 14.2 2.1 0.046 13.4 1.4 1.3 1 0 0 1 1 1 0 XLF (XRCC4-like factor) Metallophos PF00149.23 KFO95801.1 - 1.9e-44 151.4 0.4 2.3e-44 151.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 KFO95802.1 - 9.2e-13 46.4 3.3 5.1e-06 25.4 0.6 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KFO95802.1 - 7.9e-11 41.9 0.2 1.4e-06 28.3 0.1 3.1 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 KFO95802.1 - 3.7e-10 39.2 4.3 0.0015 18.1 0.2 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFO95802.1 - 6.6e-09 34.9 1.4 2.9e-06 26.7 0.5 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KFO95802.1 - 4.6e-05 22.5 3.0 0.00032 19.8 1.1 2.9 3 0 0 3 3 3 1 EF hand UPF0154 PF03672.8 KFO95802.1 - 0.091 12.3 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) mTERF PF02536.9 KFO95802.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 mTERF PH PF00169.24 KFO95803.1 - 1.9e-18 66.5 0.0 3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFO95803.1 - 1.2e-07 31.9 0.2 1.6e-05 25.1 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFO95803.1 - 3.4e-06 27.0 0.0 7.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 KFO95803.1 - 0.0065 16.5 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_7 PF15408.1 KFO95803.1 - 0.01 15.6 0.4 0.047 13.5 0.3 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.1 KFO95803.1 - 0.059 12.9 0.1 0.97 8.9 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain SM-ATX PF14438.1 KFO95804.1 - 1.3e-21 76.2 0.0 3.5e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.8 KFO95804.1 - 6.2e-15 55.0 4.7 1.4e-14 53.8 3.2 1.7 1 0 0 1 1 1 1 LsmAD domain PAM2 PF07145.10 KFO95804.1 - 7.6e-07 28.2 1.0 2.5e-06 26.5 0.7 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region BRAP2 PF07576.7 KFO95805.1 - 1.1e-41 140.8 1.4 2.2e-41 139.8 1.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KFO95805.1 - 3.5e-20 71.8 8.8 3.5e-20 71.8 6.1 2.3 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KFO95805.1 - 1.1e-09 37.8 7.0 1.1e-09 37.8 4.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFO95805.1 - 1.3e-06 27.9 5.6 1.3e-06 27.9 3.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain RRM_6 PF14259.1 KFO95805.1 - 8.8e-06 25.6 0.0 2.3e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 KFO95805.1 - 5.9e-05 22.6 6.2 5.9e-05 22.6 4.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFO95805.1 - 7.6e-05 22.7 5.7 7.6e-05 22.7 4.0 2.8 2 1 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFO95805.1 - 8.1e-05 22.5 5.6 8.1e-05 22.5 3.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO95805.1 - 0.00014 21.4 17.7 0.00041 19.9 5.3 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KFO95805.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Apc11 PF12861.2 KFO95805.1 - 0.0035 17.1 3.1 0.016 15.0 2.1 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_5 PF13893.1 KFO95805.1 - 0.0072 16.1 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GBP_C PF02841.9 KFO95805.1 - 0.1 11.7 24.0 0.11 11.7 12.9 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Baculo_PEP_C PF04513.7 KFO95805.1 - 0.18 11.6 9.5 0.095 12.5 4.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 KFO95805.1 - 0.2 11.0 3.7 0.57 9.6 0.7 2.7 1 1 1 2 2 2 0 Chordopoxvirus fusion protein Sec34 PF04136.10 KFO95805.1 - 0.28 10.8 13.6 0.58 9.8 9.4 1.4 1 0 0 1 1 1 0 Sec34-like family Adenylsucc_synt PF00709.16 KFO95805.1 - 0.29 9.7 5.4 0.45 9.1 3.7 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase DUF342 PF03961.8 KFO95805.1 - 0.38 9.1 15.0 0.57 8.5 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2317 PF10079.4 KFO95805.1 - 0.73 8.3 14.4 1.2 7.6 10.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PulS_OutS PF09691.5 KFO95805.1 - 0.94 9.4 9.5 0.33 10.9 1.5 3.3 1 1 1 4 4 4 0 Bacterial chaperone lipoprotein (PulS_OutS) NPV_P10 PF05531.7 KFO95805.1 - 0.99 9.7 8.4 7.5 6.8 4.1 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-RING_6 PF14835.1 KFO95805.1 - 4 7.2 11.2 0.5 10.1 4.1 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-ribbon_3 PF13248.1 KFO95805.1 - 4.7 6.5 8.8 4.8 6.5 4.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain APH PF01636.18 KFO95806.1 - 1.7e-37 129.4 0.1 2.6e-37 128.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.1 KFO95806.1 - 2.4e-09 37.6 0.0 2.4e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Kdo PF06293.9 KFO95806.1 - 0.00038 19.5 0.0 0.00082 18.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 KFO95806.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KFO95806.1 - 0.0025 17.1 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Hydrolase_like PF13242.1 KFO95806.1 - 0.025 14.3 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Pkinase PF00069.20 KFO95807.1 - 6.3e-62 209.0 0.0 1.5e-61 207.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95807.1 - 2.7e-22 79.1 0.1 1.4e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO95807.1 - 8.9e-06 24.8 0.0 2e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFO95807.1 - 0.00023 20.3 0.2 0.00043 19.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFO95807.1 - 0.046 13.3 0.1 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase NTP_transf_4 PF13562.1 KFO95807.1 - 0.048 13.3 0.3 0.63 9.6 0.2 2.3 1 1 0 1 1 1 0 Sugar nucleotidyl transferase APH PF01636.18 KFO95807.1 - 0.11 12.2 0.3 0.4 10.3 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Git3_C PF11970.3 KFO95808.1 - 0.0023 17.6 1.4 0.0077 15.9 1.0 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KFO95808.1 - 0.24 10.4 10.6 1.2 8.2 7.3 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) ERp29_N PF07912.8 KFO95809.1 - 5.1e-44 149.2 0.3 7.8e-44 148.6 0.2 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain ERp29 PF07749.7 KFO95809.1 - 5.5e-16 58.9 3.6 1e-15 58.1 2.5 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain PRTase_1 PF11202.3 KFO95809.1 - 0.0021 17.0 1.3 0.0034 16.4 0.9 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase (PRTase) NatB_MDM20 PF09797.4 KFO95810.1 - 8.5e-106 353.7 0.3 8.5e-106 353.7 0.2 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 KFO95810.1 - 3.2e-06 27.3 4.5 0.91 10.3 0.0 6.5 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO95810.1 - 0.00028 21.4 8.3 0.014 16.0 0.2 4.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFO95810.1 - 0.0028 17.9 10.7 0.43 10.9 0.3 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.12 KFO95810.1 - 0.14 12.4 4.9 0.17 12.1 0.3 3.1 3 1 1 4 4 4 0 Bacterial transcriptional activator domain DUF3510 PF12022.3 KFO95810.1 - 0.2 11.7 4.1 0.38 10.8 0.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) TPR_2 PF07719.12 KFO95810.1 - 0.4 10.7 8.1 12 6.1 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFO95810.1 - 0.65 9.6 13.0 1.9 8.2 0.1 4.8 4 1 2 6 6 6 0 TPR repeat HECT PF00632.20 KFO95811.1 - 2.2e-47 161.7 0.0 4.5e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps35 PF03635.12 KFO95811.1 - 0.23 9.5 0.0 0.37 8.8 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Ribosomal_L6e PF01159.14 KFO95812.1 - 3.1e-41 139.9 1.1 3.1e-41 139.9 0.8 2.2 3 0 0 3 3 3 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 KFO95812.1 - 6.3e-24 83.6 10.8 6.3e-24 83.6 7.5 3.1 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain SH2 PF00017.19 KFO95813.1 - 7.6e-25 86.5 0.0 9.6e-25 86.1 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Y_phosphatase PF00102.22 KFO95814.1 - 8e-80 267.5 0.5 1e-79 267.1 0.4 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFO95814.1 - 5.3e-06 26.0 0.1 2.5e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFO95814.1 - 0.00041 20.4 0.5 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFO95814.1 - 0.0014 18.9 0.1 0.0093 16.2 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF1092 PF06485.6 KFO95814.1 - 0.018 14.0 0.1 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) WSC PF01822.14 KFO95815.1 - 3.7e-33 113.2 15.6 8.3e-20 70.5 4.1 2.3 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.22 KFO95815.1 - 6.3e-05 22.3 0.0 0.00018 20.8 0.0 1.6 1 1 1 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFO95815.1 - 0.0066 17.3 0.0 0.01 16.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family 7tm_1 PF00001.16 KFO95816.1 - 2.5e-51 174.2 22.6 3.1e-51 174.0 15.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFO95816.1 - 8.2 5.4 26.3 0.041 12.9 11.5 1.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Fic PF02661.13 KFO95817.1 - 1.4e-27 96.2 0.0 2.9e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family TPR_11 PF13414.1 KFO95817.1 - 0.0008 19.0 1.2 0.0019 17.8 0.5 1.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFO95817.1 - 0.0014 18.4 1.0 0.018 14.9 0.3 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO95817.1 - 0.029 15.0 0.2 0.08 13.6 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat T6SS-SciN PF12790.2 KFO95817.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion lipoprotein TPR_12 PF13424.1 KFO95817.1 - 0.18 11.7 1.0 1.4 8.9 0.7 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.17 KFO95818.1 - 3.6e-33 113.0 0.1 2.2e-16 59.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95818.1 - 4.1e-25 87.5 0.0 1.2e-12 47.5 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO95818.1 - 2.7e-15 55.9 0.1 3.8e-06 26.6 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 KFO95818.1 - 1.2e-05 24.5 2.3 3.4e-05 23.0 1.6 1.8 1 0 0 1 1 1 1 Lsm interaction motif DUF1993 PF09351.5 KFO95818.1 - 0.036 13.9 2.7 9.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) RNase_H2-Ydr279 PF09468.5 KFO95818.1 - 0.059 12.5 3.7 0.12 11.4 2.6 1.6 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF908 PF06012.7 KFO95818.1 - 0.27 10.5 5.4 4.9 6.3 2.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) TPR_14 PF13428.1 KFO95818.1 - 0.75 10.6 12.8 21 6.1 0.2 6.8 6 2 3 9 9 9 0 Tetratricopeptide repeat NifU_N PF01592.11 KFO95819.1 - 1.4e-52 176.9 0.1 1.6e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Jag_N PF14804.1 KFO95819.1 - 0.042 13.8 1.2 4.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Jag N-terminus CO_deh_flav_C PF03450.12 KFO95819.1 - 0.063 13.2 0.2 0.5 10.3 0.0 2.0 1 1 1 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Proteasome PF00227.21 KFO95819.1 - 0.14 11.4 0.1 0.27 10.5 0.0 1.4 2 0 0 2 2 2 0 Proteasome subunit DUF1900 PF08954.6 KFO95820.1 - 4.2e-58 194.6 0.0 1.2e-57 193.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KFO95820.1 - 4.1e-35 119.2 0.1 7.7e-35 118.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KFO95820.1 - 4.5e-20 70.7 4.6 8.1e-08 31.8 0.2 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 KFO95820.1 - 0.039 13.6 0.0 0.15 11.7 0.0 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DSPc PF00782.15 KFO95821.1 - 2.1e-36 124.4 0.0 4.4e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 KFO95821.1 - 4.7e-18 64.6 3.7 1.3e-16 60.0 1.3 2.6 2 0 0 2 2 2 1 DEK C terminal domain Y_phosphatase PF00102.22 KFO95821.1 - 0.0049 16.2 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DAO PF01266.19 KFO95822.1 - 9.5e-28 97.1 0.1 1.6e-27 96.3 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFO95822.1 - 0.084 13.2 0.1 0.98 9.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFO95822.1 - 0.091 12.1 0.4 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.19 KFO95823.1 - 7.2e-37 127.0 28.4 5e-25 87.9 7.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFO95823.1 - 1.4e-36 125.9 36.4 3.8e-21 75.2 15.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFO95823.1 - 0.037 12.4 22.8 0.045 12.1 0.7 3.8 3 1 0 3 3 3 0 MFS/sugar transport protein UCH PF00443.24 KFO95824.1 - 2.4e-35 121.9 0.0 7.3e-35 120.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO95824.1 - 9.9e-15 54.7 1.7 5.4e-14 52.3 1.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-CHY PF05495.7 KFO95824.1 - 0.13 12.4 6.2 3.8 7.7 0.3 2.9 2 1 0 2 2 2 0 CHY zinc finger 2OG-FeII_Oxy_2 PF13532.1 KFO95825.1 - 2.5e-31 109.0 0.0 2.8e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFO95825.1 - 3.8e-05 23.9 0.0 5.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UDG PF03167.14 KFO95826.1 - 6.5e-29 100.3 0.0 8.2e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Fork_head PF00250.13 KFO95827.1 - 1.4e-30 105.1 0.4 2.6e-30 104.3 0.3 1.3 1 0 0 1 1 1 1 Fork head domain Myosin_head PF00063.16 KFO95828.1 - 5.8e-209 695.5 0.2 4.7e-172 573.6 0.4 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.7 KFO95828.1 - 0.0031 16.6 0.0 0.0076 15.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KFO95828.1 - 0.0042 17.9 0.3 0.031 15.0 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KFO95828.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFO95828.1 - 0.03 14.0 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Myosin_TH1 PF06017.8 KFO95829.1 - 5.2e-34 117.3 1.3 6e-34 117.0 0.9 1.1 1 0 0 1 1 1 1 Myosin tail FecR PF04773.8 KFO95829.1 - 0.02 15.1 0.7 3.3 7.9 0.1 3.3 1 1 2 3 3 3 0 FecR protein BTB_2 PF02214.17 KFO95830.1 - 3.5e-19 68.8 0.0 6.2e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFO95830.1 - 2.8e-05 24.0 0.0 5.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Cob_adeno_trans PF01923.13 KFO95831.1 - 2.3e-52 177.0 0.0 2.6e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase T2SF PF00482.18 KFO95831.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F GHMP_kinases_N PF00288.21 KFO95832.1 - 3.9e-22 78.0 0.9 1e-21 76.7 0.7 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFO95832.1 - 4e-06 26.9 1.2 5.8e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KFO95832.1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Ank_2 PF12796.2 KFO95833.1 - 1.9e-15 56.9 0.1 9e-06 25.9 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFO95833.1 - 9.3e-15 53.6 0.0 1.5e-06 27.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFO95833.1 - 2e-13 50.0 0.0 0.0022 18.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO95833.1 - 4.1e-12 45.0 0.1 0.00021 21.2 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFO95833.1 - 4e-08 33.5 0.2 0.02 15.3 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFO95833.1 - 3.1e-07 29.8 19.9 8.7e-07 28.3 13.8 1.8 1 1 0 1 1 1 1 Ion transport protein DUF4065 PF13274.1 KFO95833.1 - 0.031 14.9 0.0 0.067 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) GLTP PF08718.6 KFO95834.1 - 9e-31 106.9 0.0 1.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GN3L_Grn1 PF08701.6 KFO95834.1 - 0.032 14.1 0.2 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Trichoplein PF13868.1 KFO95835.1 - 3e-13 48.9 136.4 3.3e-13 48.7 94.6 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin GIT1_C PF12205.3 KFO95836.1 - 8.6e-60 199.9 3.8 2.5e-59 198.5 2.6 1.8 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_SHD PF08518.6 KFO95836.1 - 1.5e-31 107.4 2.0 2.3e-15 55.6 0.2 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ArfGap PF01412.13 KFO95836.1 - 3.6e-22 78.3 0.2 1.4e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFO95836.1 - 3e-15 56.3 0.0 1.5e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFO95836.1 - 8.9e-10 37.8 0.4 9.1e-05 22.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KFO95836.1 - 2e-09 37.6 0.0 0.00016 22.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO95836.1 - 2e-08 34.1 0.1 1.6e-07 31.3 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO95836.1 - 0.00026 20.9 0.0 0.46 10.8 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat DUF4319 PF14203.1 KFO95836.1 - 0.07 12.6 0.1 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) Shugoshin_N PF07558.6 KFO95836.1 - 0.23 11.2 6.2 0.62 9.8 4.3 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region GPCR_chapero_1 PF11904.3 KFO95837.1 - 1.8e-104 349.2 0.1 1.8e-104 349.2 0.1 1.6 2 0 0 2 2 2 1 GPCR-chaperone Ank_2 PF12796.2 KFO95837.1 - 4.7e-14 52.4 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFO95837.1 - 2.5e-13 49.0 0.0 2.6e-06 26.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFO95837.1 - 1.2e-11 44.8 0.0 4.3e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO95837.1 - 3.2e-11 43.0 0.0 2.6e-08 33.8 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO95837.1 - 7.8e-10 38.0 0.0 0.0022 18.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat RNA_pol_Rbc25 PF08292.7 KFO95837.1 - 0.0092 16.1 0.8 0.048 13.8 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 UIM PF02809.15 KFO95837.1 - 0.031 13.8 14.5 0.4 10.3 1.3 3.8 3 0 0 3 3 3 0 Ubiquitin interaction motif SNF PF00209.13 KFO95838.1 - 2.1e-142 475.2 19.1 2.3e-142 475.1 13.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family RUN PF02759.14 KFO95839.1 - 4.5e-42 142.9 0.1 1.3e-41 141.4 0.0 1.9 1 0 0 1 1 1 1 RUN domain RabGAP-TBC PF00566.13 KFO95839.1 - 4.6e-34 117.7 5.9 4.9e-32 111.1 2.5 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Crystall PF00030.14 KFO95840.1 - 7.3e-57 189.2 0.3 7.4e-28 96.2 0.0 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFO95840.1 - 0.0028 17.3 0.1 3.7 7.3 0.0 3.3 3 1 0 3 3 3 2 Beta/Gamma crystallin Crystall PF00030.14 KFO95841.1 - 5.2e-40 135.2 0.3 5.3e-28 96.7 0.1 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFO95841.1 - 4.5e-05 23.1 0.2 0.033 13.9 0.0 3.0 3 0 0 3 3 3 2 Beta/Gamma crystallin Pkinase PF00069.20 KFO95842.1 - 1.4e-70 237.4 0.0 5.9e-70 235.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95842.1 - 1.1e-28 100.0 0.0 1.7e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFO95842.1 - 6.5e-21 74.6 5.1 1.2e-20 73.7 3.5 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.24 KFO95842.1 - 1.6e-10 41.1 0.2 3.6e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KFO95842.1 - 0.00069 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO95842.1 - 0.032 13.3 0.1 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 KFO95842.1 - 0.11 12.6 2.5 0.31 11.2 0.3 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Myosin_head PF00063.16 KFO95843.1 - 4.9e-86 289.2 0.0 9.3e-86 288.3 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFO95843.1 - 2.9e-12 45.1 45.3 2.9e-12 45.1 31.4 5.2 3 3 0 4 4 4 2 Myosin tail ADIP PF11559.3 KFO95843.1 - 0.0028 17.5 14.8 0.0028 17.5 10.3 7.9 4 3 4 8 8 8 2 Afadin- and alpha -actinin-Binding IQ PF00612.22 KFO95843.1 - 0.011 15.3 0.2 0.011 15.3 0.1 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 KFO95843.1 - 0.46 9.6 22.4 0.72 8.9 0.4 4.6 5 0 0 5 5 5 0 Reovirus sigma C capsid protein Dynamin_N PF00350.18 KFO95843.1 - 3.4 7.4 0.0 3.4 7.4 0.0 4.1 5 1 0 5 5 5 0 Dynamin family Sushi PF00084.15 KFO95844.1 - 9.3e-38 128.3 20.9 4.1e-10 39.8 1.3 4.3 4 0 0 4 4 4 4 Sushi domain (SCR repeat) CUB PF00431.15 KFO95844.1 - 4.4e-21 75.0 0.0 1.9e-19 69.7 0.0 2.6 2 0 0 2 2 2 1 CUB domain Asp_Arg_Hydrox PF05118.10 KFO95845.1 - 7.7e-28 97.3 0.0 9.6e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase SRR1 PF07985.7 KFO95847.1 - 0.0029 17.4 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 GCFC PF07842.7 KFO95848.1 - 2.7e-98 328.7 17.6 1.1e-97 326.7 10.5 2.2 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KFO95848.1 - 3.7e-16 58.6 4.7 7.7e-16 57.6 3.3 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFO95848.1 - 0.00066 19.4 1.0 0.0022 17.7 0.7 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site TIP_N PF12457.3 KFO95848.1 - 0.00079 19.4 0.5 0.00079 19.4 0.3 1.8 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal Sulfotransfer_3 PF13469.1 KFO95849.1 - 5.9e-13 50.0 0.1 1.2e-12 49.0 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 KFO95849.1 - 5.4e-07 29.1 0.0 6.8e-06 25.5 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase domain Crystall PF00030.14 KFO95850.1 - 2e-58 194.2 4.6 5.4e-29 99.9 0.3 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFO95850.1 - 2.8e-07 30.1 0.2 0.012 15.3 0.0 2.8 2 2 1 3 3 3 2 Beta/Gamma crystallin Inhibitor_I36 PF03995.8 KFO95850.1 - 0.0039 17.5 0.1 0.49 10.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase inhibitor family I36 Crystall PF00030.14 KFO95851.1 - 1.8e-52 175.1 5.8 8.5e-27 92.8 0.7 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin IP_trans PF02121.13 KFO95852.1 - 7.4e-126 418.4 3.1 8.3e-126 418.3 2.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Pkinase PF00069.20 KFO95853.1 - 2.9e-73 246.2 0.0 4.1e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95853.1 - 1.2e-31 109.7 0.0 1.6e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFO95853.1 - 3.6e-13 49.4 0.0 7.3e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KFO95853.1 - 1.4e-07 30.8 0.0 2.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KFO95853.1 - 0.0044 15.8 0.1 0.011 14.5 0.0 1.6 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KFO95853.1 - 0.024 13.9 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KFO95853.1 - 0.04 12.9 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFO95853.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Sugar_tr PF00083.19 KFO95854.1 - 2.5e-91 306.5 26.4 3e-91 306.2 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFO95854.1 - 3.7e-17 62.0 25.8 3.7e-17 62.0 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily C_GCAxxG_C_C PF09719.5 KFO95854.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) bZIP_2 PF07716.10 KFO95856.1 - 1.5e-11 43.9 16.4 1.5e-11 43.9 11.4 2.5 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KFO95856.1 - 2.8e-10 39.9 16.6 2.8e-10 39.9 11.5 2.0 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KFO95856.1 - 2.5e-06 27.6 13.2 2.5e-06 27.6 9.1 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor HOOK PF05622.7 KFO95856.1 - 0.0062 14.4 8.2 0.0077 14.0 5.7 1.2 1 0 0 1 1 1 1 HOOK protein Cadherin_2 PF08266.7 KFO95856.1 - 0.038 13.5 1.8 0.073 12.6 1.2 1.5 1 0 0 1 1 1 0 Cadherin-like CCDC155 PF14662.1 KFO95856.1 - 0.18 11.4 17.7 0.25 10.8 12.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 KFO95856.1 - 0.26 11.6 13.3 2.4 8.5 8.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KFO95856.1 - 0.32 8.7 4.0 0.4 8.4 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CASP_C PF08172.7 KFO95856.1 - 0.74 8.7 9.1 0.39 9.6 5.0 1.4 1 1 0 1 1 1 0 CASP C terminal TSC22 PF01166.13 KFO95856.1 - 0.95 9.4 8.5 2.5 8.1 5.4 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 KFO95856.1 - 3.2 7.2 7.1 6.4 6.3 4.2 2.1 1 1 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KFO95856.1 - 3.7 7.0 14.8 5.8 6.4 10.3 1.3 1 0 0 1 1 1 0 IncA protein zf-RING_2 PF13639.1 KFO95857.1 - 1e-13 50.8 8.9 1e-13 50.8 6.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFO95857.1 - 3e-07 30.4 3.9 3e-07 30.4 2.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFO95857.1 - 7.4e-06 25.8 8.0 7.4e-06 25.8 5.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO95857.1 - 8.1e-06 25.4 7.8 8.1e-06 25.4 5.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO95857.1 - 1.3e-05 24.7 7.0 6.4e-05 22.5 4.9 2.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFO95857.1 - 2e-05 24.1 5.6 2e-05 24.1 3.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFO95857.1 - 0.016 14.9 2.6 0.073 12.9 1.8 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CUB PF00431.15 KFO95858.1 - 5.8e-20 71.4 0.1 1.5e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 CUB domain Kringle PF00051.13 KFO95858.1 - 2.1e-19 69.3 7.1 5.3e-19 68.0 5.0 1.7 1 0 0 1 1 1 1 Kringle domain WSC PF01822.14 KFO95858.1 - 6.7e-18 64.3 10.0 6.7e-18 64.3 6.9 1.9 2 0 0 2 2 2 1 WSC domain AMOP PF03782.12 KFO95859.1 - 3.7e-51 173.0 8.6 7e-51 172.1 6.0 1.5 1 0 0 1 1 1 1 AMOP domain VWD PF00094.20 KFO95859.1 - 1.7e-13 51.0 0.0 5.2e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type D domain Sushi PF00084.15 KFO95859.1 - 1.1e-08 35.3 0.9 3.5e-08 33.6 0.6 2.0 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Somatomedin_B PF01033.12 KFO95859.1 - 2.6e-08 33.7 11.3 2.6e-08 33.7 7.8 2.2 2 0 0 2 2 2 1 Somatomedin B domain Anophelin PF10731.4 KFO95859.1 - 0.069 13.2 0.1 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito PUF PF00806.14 KFO95860.1 - 2.1e-73 237.8 8.7 8.7e-10 37.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Mt_ATP-synt_B PF05405.9 KFO95860.1 - 2.3 7.6 5.5 9.7 5.6 0.1 3.1 3 1 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Syndecan PF01034.15 KFO95861.1 - 5.1e-32 109.3 0.1 7.8e-32 108.7 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Mtp PF03821.11 KFO95862.1 - 7.5e-73 244.7 17.3 1.6e-70 237.1 12.0 2.0 1 1 0 1 1 1 1 Golgi 4-transmembrane spanning transporter Sigma_reg_N PF13800.1 KFO95862.1 - 0.94 9.5 3.9 2.7 8.0 0.2 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal NfeD PF01957.13 KFO95862.1 - 2.1 8.5 5.7 0.69 10.0 1.1 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding VWA PF00092.23 KFO95863.1 - 5.7e-45 153.2 0.2 7.6e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.1 KFO95863.1 - 2.7e-21 75.3 50.6 1.2e-07 31.7 6.3 3.7 4 0 0 4 4 3 3 Coagulation Factor Xa inhibitory site VWA_2 PF13519.1 KFO95863.1 - 4.1e-17 62.8 0.1 5.8e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_CA PF07645.10 KFO95863.1 - 1.9e-16 59.7 39.5 4.4e-06 26.5 4.1 3.8 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.2 KFO95863.1 - 3e-15 55.5 22.9 6.1e-06 25.7 1.0 3.9 3 0 0 3 3 3 3 Complement Clr-like EGF-like Matrilin_ccoil PF10393.4 KFO95863.1 - 3.1e-09 36.0 0.2 1.1e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin VWA_3 PF13768.1 KFO95863.1 - 0.00016 21.4 0.1 0.00027 20.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF PF00008.22 KFO95863.1 - 0.0032 17.3 40.1 0.024 14.5 3.1 3.9 4 0 0 4 4 3 3 EGF-like domain vWA-TerF-like PF10138.4 KFO95863.1 - 0.0058 16.4 0.1 0.0086 15.9 0.1 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Sec23_trunk PF04811.10 KFO95863.1 - 0.041 13.2 0.3 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain ANATO PF01821.13 KFO95863.1 - 0.091 12.9 22.3 0.67 10.1 0.5 4.7 5 2 0 5 5 5 0 Anaphylotoxin-like domain EGF_3 PF12947.2 KFO95863.1 - 3.4 7.6 40.1 0.74 9.8 4.5 4.5 5 0 0 5 5 5 0 EGF domain WD40 PF00400.27 KFO95864.1 - 9.4e-13 47.5 4.3 0.0053 16.5 0.0 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFO95864.1 - 3.8e-05 22.6 3.5 0.0015 17.3 0.0 3.9 4 0 0 4 4 4 1 Coatomer WD associated region Clathrin PF00637.15 KFO95864.1 - 4.8e-05 22.9 4.3 7.5e-05 22.3 1.2 2.4 1 1 1 2 2 2 1 Region in Clathrin and VPS eIF2A PF08662.6 KFO95864.1 - 0.0009 19.0 0.7 0.011 15.4 0.3 2.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A A2L_zn_ribbon PF08792.5 KFO95864.1 - 0.0078 15.6 0.8 0.036 13.5 0.5 2.2 1 0 0 1 1 1 1 A2L zinc ribbon domain TPR_12 PF13424.1 KFO95864.1 - 7.5 6.5 11.9 14 5.7 0.4 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Zona_pellucida PF00100.18 KFO95865.1 - 8.6e-31 107.3 8.5 3e-30 105.5 0.1 3.3 3 1 0 3 3 3 2 Zona pellucida-like domain zf-H2C2_2 PF13465.1 KFO95866.1 - 3.2e-14 52.3 22.3 2.5e-07 30.6 0.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO95866.1 - 2.4e-13 49.5 24.7 8.9e-05 22.6 2.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO95866.1 - 4.2e-05 23.5 21.4 0.0044 17.2 2.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO95866.1 - 0.00062 19.5 18.0 0.0024 17.6 0.9 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO95866.1 - 0.00062 19.8 15.5 0.02 15.0 1.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.7 KFO95866.1 - 0.0013 18.6 11.1 0.18 11.8 4.1 2.7 1 1 2 3 3 3 2 TFIIH C1-like domain GAGA PF09237.6 KFO95866.1 - 0.026 14.0 2.6 0.1 12.1 0.4 2.4 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.2 KFO95866.1 - 0.042 14.0 13.7 0.072 13.3 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Rpr2 PF04032.11 KFO95866.1 - 0.068 13.0 0.7 0.068 13.0 0.5 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_Tnp_IS1595 PF12760.2 KFO95866.1 - 0.071 12.9 8.1 0.53 10.1 1.4 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain CpXC PF14353.1 KFO95866.1 - 0.082 12.8 0.1 0.082 12.8 0.0 2.9 1 1 0 2 2 2 0 CpXC protein zf-CHY PF05495.7 KFO95866.1 - 0.087 12.9 11.5 0.13 12.4 4.9 2.2 1 1 1 2 2 2 0 CHY zinc finger XPA_N PF01286.13 KFO95866.1 - 0.12 12.0 9.2 2.5 7.8 1.0 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf-AN1 PF01428.11 KFO95866.1 - 0.86 9.5 17.7 2.2 8.2 3.3 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger DUF2321 PF10083.4 KFO95866.1 - 0.87 9.0 3.1 0.52 9.7 0.6 1.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) LIM PF00412.17 KFO95866.1 - 0.9 9.6 11.8 8.1 6.5 4.2 2.5 1 1 0 2 2 2 0 LIM domain Zn-ribbon_8 PF09723.5 KFO95866.1 - 0.94 9.4 11.7 7.5 6.5 0.4 3.1 2 1 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 KFO95866.1 - 1.5 8.5 9.9 0.28 10.8 1.2 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like FYVE PF01363.16 KFO95866.1 - 3 7.8 14.4 1.6 8.7 5.0 2.4 1 1 1 2 2 2 0 FYVE zinc finger DZR PF12773.2 KFO95866.1 - 5.4 6.9 9.0 19 5.1 0.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 KFO95866.1 - 5.9 6.7 8.7 9.7 6.0 3.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-Di19 PF05605.7 KFO95866.1 - 9.7 6.4 11.7 0.38 10.9 2.9 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding 5-nucleotidase PF06189.7 KFO95867.1 - 5.2e-104 346.7 0.0 6.2e-104 346.4 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase Acid_PPase PF12689.2 KFO95867.1 - 0.025 14.2 0.0 0.065 12.8 0.0 1.7 2 0 0 2 2 2 0 Acid Phosphatase BMC PF00936.14 KFO95867.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 BMC domain adh_short PF00106.20 KFO95868.1 - 5.6e-05 23.1 0.0 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Ion_trans PF00520.26 KFO95869.1 - 3.2e-36 124.4 1.0 3.2e-36 124.4 0.7 1.6 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFO95869.1 - 1.3e-32 111.8 1.9 3e-32 110.6 0.1 2.4 3 0 0 3 3 3 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFO95869.1 - 2.2e-11 43.3 4.2 2.2e-11 43.3 2.9 1.9 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFO95869.1 - 0.002 16.6 1.3 0.0029 16.1 0.9 1.1 1 0 0 1 1 1 1 Polycystin cation channel Zona_pellucida PF00100.18 KFO95870.1 - 1.8e-36 125.9 3.5 2.2e-35 122.3 0.5 2.7 3 0 0 3 3 3 2 Zona pellucida-like domain HLH PF00010.21 KFO95871.1 - 1.1e-12 47.4 1.9 2e-12 46.6 0.9 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain XPG_I PF00867.13 KFO95872.1 - 3.3e-26 91.1 0.1 9.7e-26 89.6 0.1 1.9 1 0 0 1 1 1 1 XPG I-region SMC_N PF02463.14 KFO95873.1 - 6.6e-18 64.7 24.9 5.5e-17 61.7 17.3 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFO95873.1 - 2.1e-13 51.0 13.6 2.1e-13 51.0 9.4 5.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KFO95873.1 - 2e-06 27.9 3.9 0.0012 18.8 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KFO95873.1 - 3.9e-05 22.8 9.8 3.9e-05 22.8 6.8 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KFO95873.1 - 0.0012 18.3 0.2 0.0025 17.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KFO95873.1 - 0.025 13.7 5.5 0.19 10.8 1.1 3.1 2 1 0 3 3 3 0 Reovirus sigma C capsid protein AAA_16 PF13191.1 KFO95873.1 - 0.054 13.4 0.7 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KFO95873.1 - 3.3 6.0 85.3 0.12 10.8 9.2 5.5 3 2 2 5 5 5 0 AAA domain EF-hand_1 PF00036.27 KFO95874.1 - 4.2e-25 85.0 13.1 2.6e-08 32.5 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KFO95874.1 - 8.5e-23 78.1 4.7 8.1e-07 28.4 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KFO95874.1 - 6.1e-22 77.5 6.3 3.5e-13 49.4 0.6 3.0 1 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFO95874.1 - 6.8e-18 63.1 10.2 1.1e-06 27.6 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFO95874.1 - 1.5e-15 56.4 8.9 1.6e-05 24.3 0.4 4.3 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO95874.1 - 1.8e-05 24.7 2.0 0.0042 17.1 0.3 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFO95874.1 - 0.028 14.1 7.0 8.2 6.2 0.0 3.9 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 KFO95874.1 - 0.031 13.8 1.9 0.45 10.0 1.3 2.7 1 1 0 1 1 1 0 Caleosin related protein p25-alpha PF05517.7 KFO95874.1 - 0.13 12.4 1.0 0.39 10.9 0.0 2.1 2 1 0 2 2 2 0 p25-alpha EF-hand_10 PF14788.1 KFO95874.1 - 0.44 10.2 5.4 14 5.4 0.0 3.6 4 0 0 4 4 4 0 EF hand DUF1394 PF07159.7 KFO95876.1 - 6.5e-163 541.0 1.0 7.3e-163 540.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.1 KFO95876.1 - 0.0046 15.2 0.6 0.024 12.8 0.0 2.1 1 1 1 3 3 3 1 WASH complex subunit 7, N-terminal Endonuc-BglII PF09195.6 KFO95876.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease BglII DUF2284 PF10050.4 KFO95876.1 - 0.081 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) NUDIX_4 PF14815.1 KFO95876.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 NUDIX domain DEAD PF00270.24 KFO95877.1 - 5.8e-73 243.9 0.0 3.2e-72 241.5 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase SPRY PF00622.23 KFO95877.1 - 2.5e-25 88.9 0.2 4.8e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.26 KFO95877.1 - 2.3e-23 81.8 0.1 5.5e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KFO95877.1 - 0.0014 17.7 0.0 0.0075 15.3 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.18 KFO95877.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 KFO95877.1 - 0.095 12.5 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Nbas_N PF15492.1 KFO95878.1 - 2.4e-174 578.0 0.2 4.6e-174 577.1 0.1 1.5 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal Sec39 PF08314.6 KFO95878.1 - 4.7e-118 395.0 12.5 4.7e-118 395.0 8.7 1.9 2 0 0 2 2 2 1 Secretory pathway protein Sec39 LRAT PF04970.8 KFO95879.1 - 5.1e-09 36.1 0.1 2.8e-07 30.5 0.0 2.5 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 KFO95879.1 - 0.0049 16.6 0.0 0.017 14.9 0.0 1.9 1 1 0 1 1 1 1 NlpC/P60 family Pkinase PF00069.20 KFO95881.1 - 1e-35 123.1 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95881.1 - 6.5e-19 68.0 0.0 8.9e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO95881.1 - 4.7e-06 25.7 0.0 1.3e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFO95881.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_GDSL_2 PF13472.1 KFO95882.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family E2F_TDP PF02319.15 KFO95884.1 - 5.8e-23 80.2 0.8 1.2e-22 79.2 0.1 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 KFO95884.1 - 0.002 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.2 KFO95884.1 - 0.049 13.8 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 KFO95884.1 - 0.056 13.2 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Med4 PF10018.4 KFO95884.1 - 0.13 11.6 1.4 0.22 10.9 0.9 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 E2F_TDP PF02319.15 KFO95885.1 - 1.4e-19 69.4 0.1 3.5e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 KFO95885.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.2 KFO95885.1 - 0.038 14.2 0.0 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain RPA_interact_M PF14767.1 KFO95885.1 - 0.083 13.6 1.7 0.18 12.5 1.2 1.5 1 0 0 1 1 1 0 Replication protein A interacting middle Pkinase PF00069.20 KFO95886.1 - 1.4e-60 204.6 0.0 1.4e-60 204.6 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain Rho_Binding PF08912.6 KFO95886.1 - 6.5e-30 103.2 12.9 6.5e-30 103.2 8.9 12.0 7 3 6 13 13 8 1 Rho Binding Pkinase_Tyr PF07714.12 KFO95886.1 - 6.6e-29 100.7 0.6 3.2e-28 98.5 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.11 KFO95886.1 - 1.3e-10 40.8 14.7 1.3e-10 40.8 10.2 10.4 7 3 3 10 10 9 1 Hr1 repeat PH PF00169.24 KFO95886.1 - 2.8e-06 27.4 0.4 2.8e-06 27.4 0.2 3.4 2 1 0 2 2 2 1 PH domain Myosin_tail_1 PF01576.14 KFO95886.1 - 3.1e-05 21.9 32.4 3.1e-05 21.9 22.5 4.5 1 1 2 4 4 2 1 Myosin tail C1_1 PF00130.17 KFO95886.1 - 0.00012 21.7 6.3 0.00026 20.6 4.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Filament PF00038.16 KFO95886.1 - 0.00031 20.3 1.2 0.00031 20.3 0.8 6.7 2 1 1 4 4 3 1 Intermediate filament protein APH PF01636.18 KFO95886.1 - 0.0029 17.3 0.1 0.017 14.8 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 KFO95886.1 - 0.017 15.6 1.6 0.017 15.6 1.1 2.1 2 0 0 2 2 1 0 Protein kinase C terminal domain ACT_5 PF13710.1 KFO95886.1 - 0.33 10.7 5.8 0.24 11.2 1.4 3.0 2 0 0 2 2 2 0 ACT domain LLC1 PF14945.1 KFO95888.1 - 7.4e-05 23.0 4.6 0.00013 22.3 1.4 1.9 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Thioredoxin PF00085.15 KFO95889.1 - 6.7e-67 221.7 0.0 9.3e-33 112.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KFO95889.1 - 1.9e-14 53.8 1.0 3.5e-05 23.9 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFO95889.1 - 5.8e-11 42.3 0.0 0.00024 21.1 0.0 3.5 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.1 KFO95889.1 - 9e-10 38.6 0.0 0.07 12.9 0.0 3.2 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFO95889.1 - 5.5e-09 35.9 0.0 0.00072 19.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 KFO95889.1 - 1.2e-05 25.0 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.16 KFO95889.1 - 0.0027 17.3 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 KFO95889.1 - 0.0054 16.2 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_4 PF13462.1 KFO95889.1 - 0.0057 16.6 0.5 1.3 9.0 0.1 3.2 2 2 1 3 3 3 1 Thioredoxin HyaE PF07449.6 KFO95889.1 - 0.0079 16.0 0.0 0.71 9.8 0.0 2.3 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE FAD_binding_7 PF03441.9 KFO95889.1 - 0.09 11.9 0.0 0.88 8.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain of DNA photolyase Redoxin PF08534.5 KFO95889.1 - 0.1 12.1 0.0 5 6.6 0.0 2.3 2 0 0 2 2 2 0 Redoxin Thioredoxin_5 PF13743.1 KFO95889.1 - 0.1 12.1 0.0 40 3.7 0.0 3.4 2 2 2 4 4 4 0 Thioredoxin V-ATPase_C PF03223.10 KFO95890.1 - 1.4e-162 540.8 1.0 1.6e-162 540.6 0.7 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PhaP_Bmeg PF09602.5 KFO95890.1 - 0.0092 15.8 1.0 0.025 14.3 0.3 1.9 1 1 1 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) NUC153 PF08159.7 KFO95891.1 - 4.4e-14 51.7 1.0 8.8e-14 50.8 0.7 1.5 1 0 0 1 1 1 1 NUC153 domain Ribosomal_S16 PF00886.14 KFO95891.1 - 0.04 13.6 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S16 Orn_Arg_deC_N PF02784.11 KFO95892.1 - 1.5e-85 286.3 0.0 2e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFO95892.1 - 3.9e-33 113.6 0.1 7.4e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 KFO95892.1 - 0.036 13.3 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Cas6 PF09559.5 KFO95892.1 - 0.046 13.4 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Cas6 Crispr EF-hand_1 PF00036.27 KFO95893.1 - 3.6e-27 91.5 5.5 2.1e-07 29.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFO95893.1 - 8.4e-27 93.1 1.0 2.3e-16 59.6 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFO95893.1 - 5.2e-23 79.2 3.1 2.3e-07 29.8 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFO95893.1 - 1.4e-22 77.4 0.9 2.5e-06 26.8 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFO95893.1 - 2.6e-19 68.5 4.3 1.7e-08 33.9 0.1 4.1 2 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO95893.1 - 1.4e-07 31.5 0.0 0.00034 20.6 0.0 3.0 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFO95893.1 - 4e-06 26.5 0.7 0.15 11.8 0.0 3.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 KFO95893.1 - 0.008 15.8 2.3 2.8 7.6 0.0 3.2 4 0 0 4 4 4 2 EF hand Ribonuc_red_sm PF00268.16 KFO95894.1 - 1.7e-124 414.4 2.5 2e-124 414.1 1.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-C2H2 PF00096.21 KFO95895.1 - 1.8e-13 49.9 22.1 0.00019 21.5 0.5 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO95895.1 - 9.2e-13 47.8 9.5 9.1e-08 32.0 1.3 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO95895.1 - 8.5e-08 32.0 21.9 0.0075 16.5 1.5 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger RRN7 PF11781.3 KFO95895.1 - 0.022 14.2 2.2 0.039 13.4 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-met PF12874.2 KFO95895.1 - 0.11 12.7 8.2 3.7 7.8 0.2 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFO95895.1 - 0.16 11.9 7.4 0.38 10.7 0.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFO95895.1 - 0.34 11.0 8.7 0.084 13.0 1.2 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KFO95895.1 - 3.8 7.3 11.9 1.5 8.6 1.6 2.8 2 1 1 3 3 3 0 BED zinc finger CP2 PF04516.10 KFO95896.1 - 1.3e-83 279.6 5.5 1.9e-83 279.1 3.8 1.2 1 0 0 1 1 1 1 CP2 transcription factor RRN7 PF11781.3 KFO95897.1 - 5.5e-10 38.5 3.8 5.5e-10 38.5 2.7 2.0 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 DUF411 PF04214.8 KFO95897.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF 14-3-3 PF00244.15 KFO95898.1 - 2.4e-111 370.4 6.1 2.7e-111 370.2 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein PDDEXK_4 PF14281.1 KFO95898.1 - 0.036 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Clathrin-link PF09268.5 KFO95898.1 - 0.059 12.4 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker FliM PF02154.10 KFO95898.1 - 0.078 12.6 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Reprolysin_5 PF13688.1 KFO95899.1 - 3.4e-36 125.0 0.0 7e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFO95899.1 - 9.7e-29 100.6 0.2 1.8e-28 99.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFO95899.1 - 3.9e-22 78.8 0.3 5.7e-22 78.2 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KFO95899.1 - 8.5e-15 54.7 24.8 8.5e-15 54.7 17.2 3.2 2 1 1 3 3 3 1 Disintegrin Reprolysin PF01421.14 KFO95899.1 - 1.4e-11 44.3 1.0 8e-07 28.8 0.1 3.3 2 1 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 KFO95899.1 - 2.3e-11 44.2 0.2 4.6e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KFO95899.1 - 6.3e-10 38.9 0.1 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Lipase_GDSL PF00657.17 KFO95900.1 - 2.3e-24 86.5 0.0 2.9e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFO95900.1 - 1e-21 77.8 0.0 1.3e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CP_ATPgrasp_1 PF04174.8 KFO95900.1 - 0.16 10.5 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp CPSF73-100_C PF11718.3 KFO95901.1 - 2.5e-60 203.5 0.3 4.2e-60 202.7 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KFO95901.1 - 9.8e-33 112.7 0.0 2.4e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KFO95901.1 - 1.1e-15 57.8 0.3 1.8e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KFO95901.1 - 3e-13 49.3 0.0 7.7e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFO95901.1 - 4.1e-11 42.7 2.3 2.8e-10 40.0 0.6 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFO95901.1 - 1.1e-06 28.4 0.1 2e-05 24.3 0.0 2.7 2 1 1 3 3 3 2 Beta-lactamase superfamily domain ICAP-1_inte_bdg PF10480.4 KFO95902.1 - 4.3e-128 424.9 7.2 4.8e-128 424.8 5.0 1.0 1 0 0 1 1 1 1 Beta-1 integrin binding protein PID PF00640.18 KFO95902.1 - 0.00021 21.2 0.0 0.00056 19.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) YCII PF03795.9 KFO95902.1 - 0.06 13.5 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 YCII-related domain Glyco_hydro_31 PF01055.21 KFO95903.1 - 6.2e-95 318.6 1.4 8.3e-52 176.4 0.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Ras PF00071.17 KFO95904.1 - 3.5e-33 114.2 0.0 4.7e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95904.1 - 3.1e-09 37.3 0.0 4.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO95904.1 - 1.3e-07 30.9 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFO95904.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2890 PF11081.3 KFO95905.1 - 1.1 9.2 19.7 0.94 9.5 12.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) DUF605 PF04652.11 KFO95905.1 - 3.8 6.8 18.6 4.4 6.6 12.9 1.0 1 0 0 1 1 1 0 Vta1 like RVT_1 PF00078.22 KFO95906.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.17 KFO95907.1 - 1e-12 47.4 0.0 1.9e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO95907.1 - 2.8e-07 30.4 0.0 1.4e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.16 KFO95907.1 - 0.055 13.3 0.0 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 Hsp20/alpha crystallin family zf-U1 PF06220.7 KFO95907.1 - 0.061 12.8 0.3 0.17 11.4 0.2 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-B_box PF00643.19 KFO95907.1 - 0.074 12.9 6.2 0.18 11.7 4.3 1.6 1 0 0 1 1 1 0 B-box zinc finger C1q PF00386.16 KFO95908.1 - 1.2e-38 131.9 0.0 1.6e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFO95908.1 - 2.4e-16 59.0 57.6 1.6e-09 37.1 17.6 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CC2D2AN-C2 PF15625.1 KFO95909.1 - 7.8e-41 139.3 0.0 1.5e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.25 KFO95909.1 - 8.7e-05 22.2 0.1 0.024 14.4 0.0 2.7 2 0 0 2 2 2 2 C2 domain DUF3987 PF13148.1 KFO95909.1 - 0.76 8.2 19.6 0.034 12.7 8.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) F-box-like PF12937.2 KFO95910.1 - 7.9e-16 57.5 0.1 2.6e-15 55.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KFO95910.1 - 3.6e-13 48.1 0.9 0.044 13.8 0.0 5.1 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 KFO95910.1 - 4.4e-12 45.3 1.2 9.8e-06 25.0 0.0 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 KFO95910.1 - 8.8e-11 41.1 0.1 6.7e-10 38.3 0.0 2.4 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 KFO95910.1 - 5.5e-09 34.8 3.6 0.072 13.1 0.0 5.6 5 0 0 5 5 4 3 Leucine Rich Repeat Hemerythrin PF01814.18 KFO95910.1 - 1.7e-08 34.7 0.2 3.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain LRR_8 PF13855.1 KFO95910.1 - 3.3e-07 29.9 1.5 0.0013 18.4 0.0 3.4 2 1 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KFO95910.1 - 5.2e-07 28.8 1.8 0.69 10.3 0.0 5.5 4 0 0 4 4 4 1 Leucine rich repeat PRANC PF09372.5 KFO95910.1 - 0.027 14.4 0.0 0.11 12.4 0.0 2.1 1 0 0 1 1 1 0 PRANC domain Orthopox_A5L PF06193.6 KFO95910.1 - 0.035 14.0 2.3 0.084 12.8 1.6 1.6 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like NAAA-beta PF15508.1 KFO95910.1 - 0.31 11.4 2.9 0.43 10.9 0.3 2.5 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Rib_hydrolayse PF02267.12 KFO95911.1 - 4.1e-18 65.6 0.0 4.4e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase Rib_hydrolayse PF02267.12 KFO95912.1 - 8.3e-94 313.4 0.2 9.6e-94 313.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosyl cyclase FGF-BP1 PF06473.7 KFO95913.1 - 1e-48 165.9 14.4 4.5e-48 163.8 10.0 1.8 1 1 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) FGF-BP1 PF06473.7 KFO95914.1 - 2e-56 191.2 0.5 2.4e-56 190.9 0.3 1.1 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Dehydratase_MU PF02288.10 KFO95914.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Dehydratase medium subunit Prominin PF05478.6 KFO95915.1 - 2.7e-271 901.7 13.0 3.3e-271 901.4 9.0 1.0 1 0 0 1 1 1 1 Prominin IncA PF04156.9 KFO95915.1 - 0.085 12.4 0.1 0.085 12.4 0.1 3.3 3 0 0 3 3 3 0 IncA protein DUF747 PF05346.6 KFO95916.1 - 8.7e-97 324.1 19.9 1.5e-96 323.3 13.8 1.4 1 1 0 1 1 1 1 Eukaryotic membrane protein family DASH_Dad4 PF08650.5 KFO95916.1 - 0.056 13.3 2.0 0.99 9.3 1.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 LIM_bind PF01803.11 KFO95917.1 - 9.2e-69 231.1 2.6 9.2e-69 231.1 1.8 2.7 2 1 0 2 2 2 1 LIM-domain binding protein Vpu PF00558.14 KFO95917.1 - 0.43 10.1 1.6 5.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Vpu protein Peptidase_M17 PF00883.16 KFO95919.1 - 5.4e-113 376.9 0.1 3.5e-112 374.3 0.1 1.9 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KFO95919.1 - 5.4e-23 81.0 0.0 1e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Med28 PF11594.3 KFO95920.1 - 1.4e-43 147.4 1.0 1.7e-43 147.1 0.7 1.1 1 0 0 1 1 1 1 Mediator complex subunit 28 HTH_34 PF13601.1 KFO95920.1 - 0.0019 18.2 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain Filament PF00038.16 KFO95920.1 - 0.0026 17.2 1.2 0.0035 16.8 0.8 1.3 1 1 0 1 1 1 1 Intermediate filament protein ISG65-75 PF11727.3 KFO95920.1 - 0.056 12.4 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Fib_alpha PF08702.5 KFO95920.1 - 0.14 12.2 3.2 0.2 11.7 2.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.8 KFO95920.1 - 0.51 9.7 4.1 0.7 9.2 2.8 1.3 1 1 0 1 1 1 0 fzo-like conserved region Cnd3 PF12719.2 KFO95921.1 - 1e-75 254.5 4.1 4.1e-75 252.5 2.6 2.2 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KFO95921.1 - 1.3e-11 44.6 10.3 0.00042 20.5 0.3 5.7 5 1 0 6 6 6 3 HEAT repeats HEAT PF02985.17 KFO95921.1 - 1.7e-08 33.8 4.2 2.3 8.5 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KFO95921.1 - 0.0011 19.3 10.0 0.96 10.0 0.2 5.5 6 0 0 6 6 6 2 HEAT-like repeat UVR PF02151.14 KFO95921.1 - 0.058 12.9 0.2 0.058 12.9 0.2 2.3 2 0 0 2 2 2 0 UvrB/uvrC motif SRR1 PF07985.7 KFO95921.1 - 0.17 11.8 1.8 0.36 10.7 0.4 2.1 2 0 0 2 2 2 0 SRR1 DUF4553 PF15090.1 KFO95922.1 - 3.6e-176 586.7 29.6 3.6e-176 586.7 20.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4553) HTH_psq PF05225.11 KFO95923.1 - 1.9e-22 78.5 0.0 4.3e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 helix-turn-helix, Psq domain Thioredoxin PF00085.15 KFO95924.1 - 3.1e-29 100.7 0.1 3.7e-29 100.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFO95924.1 - 4.3e-09 36.5 0.0 2e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFO95924.1 - 1.5e-06 28.1 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KFO95924.1 - 1e-05 25.5 0.0 0.00028 20.9 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KFO95924.1 - 0.00029 20.5 0.1 0.0004 20.1 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.16 KFO95924.1 - 0.0019 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KFO95924.1 - 0.0098 15.4 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KFO95924.1 - 0.011 15.3 0.0 0.26 10.8 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Redoxin PF08534.5 KFO95924.1 - 0.039 13.4 0.6 0.22 11.0 0.1 1.9 1 1 1 2 2 2 0 Redoxin DUF836 PF05768.9 KFO95924.1 - 0.053 13.7 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Pyr_redox_3 PF13738.1 KFO95925.1 - 1e-37 130.1 0.0 1.6e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFO95925.1 - 7.8e-09 34.8 0.0 5.5e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFO95925.1 - 3.5e-08 33.5 0.0 1.2e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFO95925.1 - 3.3e-07 30.2 0.0 9.9e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFO95925.1 - 6.5e-06 25.2 0.0 8.9e-05 21.5 0.0 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFO95925.1 - 9.2e-06 24.3 0.0 0.0023 16.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FMO-like PF00743.14 KFO95925.1 - 2.1e-05 22.9 0.0 7.2e-05 21.1 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.12 KFO95925.1 - 9.2e-05 21.6 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KFO95925.1 - 0.00056 19.7 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFO95925.1 - 0.0013 17.6 0.0 0.0043 15.9 0.0 1.6 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KFO95925.1 - 0.01 16.1 0.0 0.96 9.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFO95925.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Peptidase_C71 PF12386.3 KFO95925.1 - 0.07 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei GIDA PF01134.17 KFO95925.1 - 0.095 11.5 0.0 0.91 8.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF313 PF03754.8 KFO95925.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF313) eIF-3_zeta PF05091.7 KFO95926.1 - 9.2e-213 707.5 4.2 1.1e-212 707.3 2.9 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PMP22_Claudin PF00822.15 KFO95927.1 - 8.2e-58 194.7 1.8 1.1e-57 194.3 1.2 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO95927.1 - 2.4e-21 76.1 0.9 4e-21 75.4 0.6 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.1 KFO95927.1 - 0.0013 17.3 0.8 0.0017 16.9 0.6 1.2 1 0 0 1 1 1 1 Amino acid permease Tetraspannin PF00335.15 KFO95927.1 - 0.0047 16.2 0.0 0.0078 15.5 0.0 1.5 1 0 0 1 1 1 1 Tetraspanin family Ras PF00071.17 KFO95928.1 - 2.3e-36 124.6 0.1 2.6e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95928.1 - 2.4e-15 57.0 0.0 3.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFO95928.1 - 7.5e-05 22.2 0.0 8.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFO95928.1 - 0.00026 20.9 0.0 0.00039 20.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KFO95928.1 - 0.00038 19.7 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family EF-hand_1 PF00036.27 KFO95929.1 - 1.5e-13 48.9 2.3 2e-06 26.6 0.5 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFO95929.1 - 4e-12 44.9 1.6 5.2e-07 29.0 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFO95929.1 - 9.2e-12 43.7 1.5 0.0001 21.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFO95929.1 - 2.2e-11 43.1 0.9 1.6e-08 33.9 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 KFO95929.1 - 1.3e-10 41.2 0.3 1.9e-10 40.7 0.2 1.5 1 1 0 1 1 1 1 EF-hand domain pair EFhand_Ca_insen PF08726.5 KFO95929.1 - 0.075 13.0 0.2 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.4 KFO95929.1 - 0.13 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region SAC3_GANP PF03399.11 KFO95929.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PX PF00787.19 KFO95930.1 - 8.9e-18 64.1 0.0 1.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 KFO95930.1 - 2e-16 59.3 2.1 5.1e-16 58.0 0.6 2.1 2 0 0 2 2 2 1 PB1 domain SH3_1 PF00018.23 KFO95930.1 - 1.2e-11 43.7 0.0 2.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFO95930.1 - 6.4e-11 41.6 0.2 1.4e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFO95930.1 - 2.1e-09 36.7 0.0 7.2e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain fn3 PF00041.16 KFO95931.1 - 7.4e-16 58.0 4.7 8.1e-08 32.2 0.0 5.1 5 1 0 5 5 5 3 Fibronectin type III domain IL6Ra-bind PF09240.5 KFO95931.1 - 8e-13 48.4 7.3 3.2e-07 30.4 0.1 2.6 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFO95931.1 - 1.6e-07 31.0 6.2 5e-05 22.9 0.0 3.4 2 1 1 3 3 3 2 Tissue factor EpoR_lig-bind PF09067.5 KFO95931.1 - 4.7e-07 29.7 8.2 7.3e-05 22.7 0.0 3.4 4 0 0 4 4 4 2 Erythropoietin receptor, ligand binding IL4Ra_N PF09238.5 KFO95931.1 - 2.5e-06 27.4 7.6 0.053 13.6 0.5 4.1 3 1 1 4 4 4 3 Interleukin-4 receptor alpha chain, N-terminal IL12p40_C PF10420.4 KFO95931.1 - 0.11 12.5 2.4 0.79 9.8 0.2 2.7 2 1 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus TEX33 PF15400.1 KFO95932.1 - 1.5e-33 116.1 0.1 1.6e-33 116.0 0.1 1.0 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family Rhodanese PF00581.15 KFO95933.1 - 2.3e-26 92.3 0.0 3.7e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Rhodanese PF00581.15 KFO95935.1 - 7e-31 106.9 0.0 2.8e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain B12D PF06522.6 KFO95935.1 - 0.11 12.2 0.2 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit BTB_2 PF02214.17 KFO95936.1 - 1.9e-22 79.2 0.0 3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFO95936.1 - 0.013 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF4206 PF13901.1 KFO95936.1 - 0.09 12.3 0.5 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) fn3 PF00041.16 KFO95937.1 - 3.9e-07 30.1 0.6 7.7e-07 29.1 0.4 1.6 1 1 0 1 1 1 1 Fibronectin type III domain DUF3943 PF13084.1 KFO95937.1 - 0.018 14.6 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) C1q PF00386.16 KFO95938.1 - 2.6e-33 114.7 1.2 3.2e-33 114.4 0.8 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFO95938.1 - 5.7e-09 35.3 15.4 8.4e-09 34.8 10.7 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.16 KFO95939.1 - 7.5e-66 221.8 20.0 1e-65 221.4 13.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO95939.1 - 3.7e-12 45.9 12.5 4.6e-12 45.6 8.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO95939.1 - 6.1e-07 28.8 9.2 8.4e-07 28.3 6.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 KFO95939.1 - 7.4e-06 25.2 5.2 7.4e-06 25.2 3.6 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFO95939.1 - 0.00013 21.2 13.3 0.017 14.2 9.2 2.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Serpentine_r_xa PF03383.10 KFO95939.1 - 0.0002 21.1 0.7 0.0002 21.1 0.5 2.9 2 1 1 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa TAS2R PF05296.8 KFO95939.1 - 0.018 13.9 12.9 0.083 11.7 9.0 1.9 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) DUF2028 PF09667.5 KFO95939.1 - 0.048 13.7 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) Rab5ip PF07019.7 KFO95939.1 - 0.4 10.8 4.5 0.19 11.8 0.5 2.4 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Dicty_CAR PF05462.6 KFO95939.1 - 1.1 8.1 17.6 2.8 6.7 12.2 1.6 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Ras PF00071.17 KFO95940.1 - 2.6e-54 182.9 0.0 2.9e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO95940.1 - 1.5e-16 60.9 0.0 2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO95940.1 - 1.3e-07 31.0 0.0 2.1e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO95940.1 - 0.0027 17.1 0.0 0.026 13.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Sec7 PF01369.15 KFO95941.1 - 2.2e-64 216.6 0.0 3.6e-64 215.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KFO95941.1 - 5.3e-24 84.4 0.1 9.4e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFO95941.1 - 9e-08 32.3 0.1 2.1e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain Syntaxin-6_N PF09177.6 KFO95941.1 - 0.0031 17.8 2.3 0.39 11.1 0.0 2.7 2 0 0 2 2 2 1 Syntaxin 6, N-terminal PH_6 PF15406.1 KFO95941.1 - 0.0086 16.1 0.0 0.44 10.6 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFO95941.1 - 0.012 15.4 0.0 0.038 13.8 0.0 1.9 1 1 0 1 1 1 0 PH domain Phage_Mu_Gam PF07352.7 KFO95941.1 - 0.017 14.6 0.8 0.032 13.7 0.6 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Laminin_I PF06008.9 KFO95941.1 - 0.062 12.6 0.5 0.1 11.8 0.3 1.3 1 0 0 1 1 1 0 Laminin Domain I DUF2205 PF10224.4 KFO95941.1 - 0.37 10.3 3.2 0.76 9.3 2.2 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) LRR_8 PF13855.1 KFO95942.1 - 3e-21 74.9 10.3 1.3e-15 56.8 0.6 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFO95942.1 - 2.1e-08 33.5 13.0 0.00091 18.7 0.1 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFO95942.1 - 2.7e-07 30.3 1.0 8.8e-07 28.6 0.3 2.1 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) fn3 PF00041.16 KFO95942.1 - 0.0087 16.1 0.2 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LRR_1 PF00560.28 KFO95942.1 - 0.0089 15.9 15.5 2.3 8.5 0.4 5.5 6 0 0 6 6 6 2 Leucine Rich Repeat Herpes_gE PF02480.11 KFO95942.1 - 0.0093 14.2 0.3 0.015 13.6 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E LRR_6 PF13516.1 KFO95942.1 - 0.013 15.4 11.5 2.1 8.6 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich repeat DUF2816 PF10992.3 KFO95942.1 - 0.054 13.0 0.3 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2816) Fringe PF02434.11 KFO95943.1 - 5.2e-107 356.7 0.0 6e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KFO95943.1 - 0.0089 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase DUF2785 PF10978.3 KFO95943.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) Glycos_transf_2 PF00535.21 KFO95943.1 - 0.14 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 BORG_CEP PF14957.1 KFO95944.1 - 2e-16 61.0 2.0 1.1e-14 55.3 1.4 2.2 1 1 0 1 1 1 1 Cdc42 effector PBD PF00786.23 KFO95944.1 - 1.3e-07 31.8 1.5 4.5e-07 30.2 1.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Gal-bind_lectin PF00337.17 KFO95945.1 - 1.7e-30 105.1 0.0 1.8e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin SH3_1 PF00018.23 KFO95945.1 - 0.15 11.4 0.1 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 SH3 domain VHS PF00790.14 KFO95946.1 - 3.7e-37 127.1 1.8 1.8e-36 124.8 0.0 2.3 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 KFO95946.1 - 2.9e-34 117.0 5.1 2.9e-34 117.0 3.5 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 KFO95946.1 - 8.8e-28 96.9 0.6 2.7e-27 95.3 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain DUF1313 PF07011.6 KFO95946.1 - 0.0015 18.1 4.0 0.052 13.2 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1313) Ferritin PF00210.19 KFO95946.1 - 0.025 14.3 2.0 0.14 11.9 1.2 2.0 2 0 0 2 2 2 0 Ferritin-like domain DUF1910 PF08928.5 KFO95946.1 - 0.1 12.5 0.4 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DUF2877 PF11392.3 KFO95946.1 - 0.19 11.9 0.3 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Fib_alpha PF08702.5 KFO95946.1 - 2.6 8.1 6.8 5.9 7.0 4.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RhoGAP PF00620.22 KFO95947.1 - 4.8e-45 152.8 0.1 1.2e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.13 KFO95947.1 - 2.8e-23 82.6 3.3 4.5e-23 81.9 2.3 1.3 1 0 0 1 1 1 1 BAR domain Hydrolase_like PF13242.1 KFO95947.1 - 1.8e-19 69.2 0.0 3.4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KFO95947.1 - 2.8e-06 27.6 0.0 5.7e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFO95947.1 - 1.2e-05 25.8 0.0 2.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KFO95947.1 - 0.033 13.5 0.0 0.078 12.3 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DUF2935 PF11155.3 KFO95947.1 - 0.092 12.8 0.1 0.62 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Glyco_transf_10 PF00852.14 KFO95947.1 - 0.15 10.5 0.4 1.9 6.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 10 (fucosyltransferase) Ribosomal_60s PF00428.14 KFO95947.1 - 0.24 11.7 3.9 3.2 8.2 0.5 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2360 PF10152.4 KFO95947.1 - 8.7 6.6 7.1 12 6.1 2.9 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Gal-bind_lectin PF00337.17 KFO95948.1 - 2.7e-31 107.6 0.0 3.1e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin ChitinaseA_N PF08329.5 KFO95948.1 - 0.055 13.2 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Chitinase A, N-terminal domain ArfGap PF01412.13 KFO95949.1 - 3.7e-37 126.6 0.2 7.7e-37 125.6 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 KFO95949.1 - 1.8e-17 63.4 0.4 3.2e-09 36.9 0.1 2.8 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 KFO95949.1 - 7.9e-11 42.1 0.7 5.5e-07 29.8 0.2 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFO95949.1 - 1.7e-06 28.0 0.8 0.024 14.6 0.0 3.1 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 KFO95949.1 - 1.6e-05 24.7 0.5 0.0027 17.5 0.0 3.2 2 1 0 2 2 2 1 PH domain Nop25 PF09805.4 KFO95950.1 - 2.6e-19 69.6 12.9 5.2e-19 68.6 9.0 1.7 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) DUF572 PF04502.8 KFO95950.1 - 0.14 11.3 10.6 0.19 10.9 7.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RAP1 PF07218.6 KFO95950.1 - 6.6 4.6 6.6 9.9 4.1 4.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PH PF00169.24 KFO95951.1 - 1.5e-14 54.0 0.1 4.5e-14 52.5 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFO95951.1 - 0.00011 22.4 0.5 0.00011 22.4 0.3 3.6 3 2 1 4 4 4 1 Pleckstrin homology domain HALZ PF02183.13 KFO95951.1 - 0.02 14.5 1.1 0.02 14.5 0.8 5.6 6 0 0 6 6 6 0 Homeobox associated leucine zipper Cellulose_synt PF03552.9 KFO95951.1 - 0.47 8.6 1.3 0.74 8.0 0.9 1.2 1 0 0 1 1 1 0 Cellulose synthase Aminotran_1_2 PF00155.16 KFO95952.1 - 1.5e-72 244.5 0.0 1.8e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFO95952.1 - 5.5e-08 31.9 0.0 1.3e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KFO95952.1 - 7.6e-05 21.1 0.0 0.00012 20.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KFO95952.1 - 0.00029 20.0 0.0 0.00049 19.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFO95952.1 - 0.098 11.6 0.4 0.75 8.7 0.3 2.1 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 KFO95952.1 - 0.12 10.8 0.0 1.8 7.0 0.0 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain 7tm_1 PF00001.16 KFO95953.1 - 3e-56 190.4 19.1 3.4e-56 190.2 13.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFO95953.1 - 3.5e-08 32.9 14.4 5.3e-06 25.7 10.0 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF420 PF04238.7 KFO95953.1 - 0.78 9.6 12.7 0.095 12.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Ank PF00023.25 KFO95954.1 - 1.1e-26 91.2 9.9 1.2e-11 43.7 0.1 4.4 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KFO95954.1 - 6.8e-26 90.4 0.3 6.7e-14 51.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFO95954.1 - 1.9e-21 75.6 5.8 5e-13 48.8 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO95954.1 - 7.1e-21 74.1 0.7 8.3e-09 35.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO95954.1 - 6.6e-16 56.8 1.2 1.4e-06 27.9 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat DUF3926 PF13080.1 KFO95954.1 - 0.12 11.9 2.0 0.17 11.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3926) Paf67 PF10255.4 KFO95955.1 - 2.3e-162 540.4 9.3 3.5e-162 539.9 6.4 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Apc3 PF12895.2 KFO95955.1 - 0.00079 19.5 0.2 0.003 17.6 0.2 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KFO95955.1 - 0.0016 18.1 0.4 0.037 13.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFO95955.1 - 0.012 15.2 0.3 0.42 10.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFO95955.1 - 0.013 15.4 0.2 0.048 13.5 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat SPG48 PF14764.1 KFO95955.1 - 0.054 11.9 0.1 0.13 10.7 0.1 1.5 1 1 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking TPR_16 PF13432.1 KFO95955.1 - 0.13 13.0 0.0 0.46 11.2 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF3585 PF12130.3 KFO95956.1 - 5.9e-46 155.8 12.5 9e-46 155.2 8.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) CH PF00307.26 KFO95956.1 - 2.1e-17 63.1 0.0 3.6e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFO95956.1 - 8.6e-09 34.9 0.0 1.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.17 KFO95956.1 - 9.7e-09 35.1 4.5 1.9e-08 34.2 3.1 1.5 1 0 0 1 1 1 1 LIM domain UPF0193 PF05250.6 KFO95957.1 - 2.3e-50 171.1 7.2 2.7e-50 170.8 5.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) V_ATPase_I PF01496.14 KFO95957.1 - 1 7.1 4.1 1.3 6.7 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RasGAP_C PF03836.10 KFO95957.1 - 3.2 7.4 8.2 0.35 10.5 2.5 1.7 2 0 0 2 2 2 0 RasGAP C-terminus RPA_interact_M PF14767.1 KFO95957.1 - 4.4 8.1 7.9 8.8 7.1 5.5 1.6 1 1 0 1 1 1 0 Replication protein A interacting middle RNA_pol_Rpb6 PF01192.17 KFO95958.1 - 1.3e-21 76.0 0.3 1.3e-21 76.0 0.2 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 YL1 PF05764.8 KFO95958.1 - 0.045 13.3 0.9 0.055 13.0 0.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Tropomodulin PF03250.9 KFO95958.1 - 0.069 12.6 0.4 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 Tropomodulin Sox_N PF12444.3 KFO95959.1 - 6.8e-26 91.1 0.3 6.8e-26 91.1 0.2 2.4 3 1 0 3 3 3 1 Sox developmental protein N terminal HMG_box PF00505.14 KFO95959.1 - 2e-24 85.6 1.4 3.4e-24 84.8 1.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO95959.1 - 4.9e-10 39.6 0.9 4.9e-10 39.6 0.6 1.7 2 0 0 2 2 2 1 HMG-box domain MAT_Alpha1 PF04769.7 KFO95959.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 Arfaptin PF06456.8 KFO95960.1 - 5.6e-85 284.3 1.6 9.1e-85 283.6 1.1 1.3 1 0 0 1 1 1 1 Arfaptin-like domain PDZ PF00595.19 KFO95960.1 - 1.1e-10 41.5 0.1 2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO95960.1 - 5.4e-06 26.2 0.3 3e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 PDZ domain BAR PF03114.13 KFO95960.1 - 8.6e-06 25.4 1.3 2.5e-05 23.9 0.8 1.8 1 1 1 2 2 2 1 BAR domain GRASP55_65 PF04495.9 KFO95960.1 - 0.052 13.5 0.0 0.66 9.9 0.0 2.2 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain MFS_1 PF07690.11 KFO95961.1 - 2.9e-32 111.7 23.6 3.8e-32 111.3 16.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.2 KFO95962.1 - 2.1e-47 159.3 6.1 4.4e-15 55.7 0.2 3.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFO95962.1 - 4.4e-38 127.2 7.3 1.2e-07 31.1 0.0 7.6 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KFO95962.1 - 5.2e-30 100.5 6.8 1.3e-05 25.0 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KFO95962.1 - 2.4e-28 97.9 2.3 2.5e-09 37.4 0.0 6.1 2 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO95962.1 - 6.7e-28 96.0 5.7 2.7e-07 30.6 0.0 6.9 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Patatin PF01734.17 KFO95962.1 - 3e-19 69.7 0.9 1.2e-18 67.7 0.6 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase SpoIIAA-like PF11964.3 KFO95962.1 - 0.079 13.2 0.1 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 SpoIIAA-like bZIP_Maf PF03131.12 KFO95963.1 - 8e-33 112.6 8.4 1e-32 112.2 5.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KFO95963.1 - 0.0092 15.7 7.8 0.0092 15.7 5.4 2.4 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KFO95963.1 - 0.014 15.3 13.1 0.056 13.4 8.6 2.3 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 KFO95963.1 - 0.016 14.6 6.1 0.016 14.6 0.7 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 KFO95963.1 - 0.041 13.6 0.4 0.041 13.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF972 PF06156.8 KFO95963.1 - 0.091 13.1 2.8 0.16 12.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KFO95963.1 - 0.23 11.0 2.9 0.59 9.6 1.8 1.7 1 1 1 2 2 2 0 IncA protein SNN_transmemb PF09049.5 KFO95963.1 - 0.37 10.5 1.5 0.54 9.9 1.0 1.2 1 0 0 1 1 1 0 Stannin transmembrane GAS PF13851.1 KFO95963.1 - 0.76 8.9 5.9 1.3 8.1 4.0 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 KFO95963.1 - 1.3 8.8 9.1 0.46 10.2 0.4 3.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF904 PF06005.7 KFO95963.1 - 3.9 7.8 8.4 23 5.3 5.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 KFO95963.1 - 7.5 7.0 6.3 2.3e+02 2.2 4.4 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Solute_trans_a PF03619.11 KFO95964.1 - 5.2e-98 327.7 19.6 6.4e-98 327.4 13.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pkinase PF00069.20 KFO95965.1 - 2.4e-32 112.1 0.0 3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO95965.1 - 2.9e-12 46.2 0.0 3.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFO95965.1 - 0.00011 22.0 0.4 0.00064 19.5 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFO95965.1 - 0.024 13.4 0.2 0.038 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IRK PF01007.15 KFO95966.1 - 3.3e-170 565.3 0.0 3.8e-170 565.1 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFO95966.1 - 0.1 12.3 13.3 0.64 9.7 9.2 2.2 1 1 0 1 1 1 0 Ion channel ER_lumen_recept PF00810.13 KFO95967.1 - 2.1e-56 190.4 11.6 3.8e-56 189.6 8.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KFO95967.1 - 0.003 17.0 10.1 0.049 13.1 0.6 3.2 3 1 0 3 3 3 2 PQ loop repeat Cation_ATPase_C PF00689.16 KFO95967.1 - 7 6.1 10.7 0.23 10.9 2.1 2.2 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus DEAD PF00270.24 KFO95968.1 - 2.4e-45 154.0 0.0 4.9e-44 149.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO95968.1 - 6.4e-26 90.0 0.0 1.3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFO95968.1 - 0.007 16.2 0.0 0.03 14.1 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Ferritin PF00210.19 KFO95968.1 - 0.0088 15.8 0.8 0.031 14.0 0.5 1.9 1 1 0 1 1 1 1 Ferritin-like domain Helicase_C_2 PF13307.1 KFO95968.1 - 0.054 13.4 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Rad51 PF08423.6 KFO95969.1 - 3.3e-122 406.3 0.1 4.2e-122 405.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KFO95969.1 - 2.9e-10 39.7 0.0 3.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 KFO95969.1 - 4.6e-10 39.2 0.0 6.3e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFO95969.1 - 2.1e-07 30.2 0.1 4.1e-07 29.3 0.1 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 KFO95969.1 - 2.3e-06 27.6 0.1 5.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF128 PF01995.11 KFO95969.1 - 0.0035 16.3 0.0 0.0062 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF128 HHH PF00633.18 KFO95969.1 - 0.057 13.1 0.0 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif DnaB_C PF03796.10 KFO95969.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Chibby PF14645.1 KFO95970.1 - 1.6e-50 169.8 1.2 1.8e-50 169.6 0.8 1.0 1 0 0 1 1 1 1 Chibby family Taxilin PF09728.4 KFO95970.1 - 0.00086 18.4 2.1 0.001 18.2 1.4 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein UPF0242 PF06785.6 KFO95970.1 - 0.002 16.8 2.1 0.0023 16.6 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) DUF972 PF06156.8 KFO95970.1 - 0.029 14.7 4.5 0.043 14.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2051 PF09738.4 KFO95970.1 - 0.03 13.6 5.1 0.037 13.3 3.5 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) bZIP_2 PF07716.10 KFO95970.1 - 1.2 9.0 11.4 0.22 11.3 4.8 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Shugoshin_N PF07558.6 KFO95970.1 - 1.3 8.7 9.6 0.31 10.7 3.0 2.4 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 KFO95970.1 - 2.5 7.6 6.0 1.5 8.3 2.3 1.8 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.13 KFO95970.1 - 4.3 7.3 8.7 1 9.3 2.7 2.0 1 1 1 2 2 2 0 TSC-22/dip/bun family Josephin PF02099.12 KFO95971.1 - 1.7e-28 99.2 0.2 1.3e-27 96.3 0.2 1.9 1 1 0 1 1 1 1 Josephin GTP_EFTU PF00009.22 KFO95972.1 - 3.4e-27 95.0 0.0 5.4e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFO95972.1 - 3.7e-18 65.5 0.7 8.9e-18 64.2 0.0 2.1 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFO95972.1 - 2.9e-07 30.5 0.3 1.8e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KFO95972.1 - 0.00023 20.6 0.0 1 8.8 0.0 3.6 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KFO95972.1 - 0.0017 18.2 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFO95972.1 - 0.0041 17.6 0.1 0.045 14.2 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 KFO95972.1 - 0.083 12.6 0.3 0.65 9.7 0.1 2.3 1 1 1 2 2 2 0 Dynamin family Arf PF00025.16 KFO95972.1 - 0.14 11.3 0.1 12 5.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Sad1_UNC PF07738.8 KFO95973.1 - 1.1e-43 148.3 0.0 1.7e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spc7 PF08317.6 KFO95973.1 - 0.0051 15.5 2.2 0.0093 14.6 1.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Leu_zip PF15294.1 KFO95973.1 - 0.0097 15.0 3.5 0.019 14.0 2.4 1.4 1 0 0 1 1 1 1 Leucine zipper DUF4618 PF15397.1 KFO95973.1 - 0.036 13.3 2.4 0.096 12.0 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DivIC PF04977.10 KFO95973.1 - 0.099 12.1 6.8 1.1 8.7 0.0 3.6 3 0 0 3 3 3 0 Septum formation initiator Baculo_PEP_C PF04513.7 KFO95973.1 - 0.15 11.8 0.2 0.48 10.2 0.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.6 KFO95973.1 - 0.2 11.7 2.0 0.24 11.4 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) COG2 PF06148.6 KFO95973.1 - 1.5 8.7 5.1 6.8 6.5 1.5 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 KFO95973.1 - 2 7.3 6.4 0.48 9.3 0.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1193 PF06702.7 KFO95974.1 - 1.1e-105 351.9 0.0 1.4e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 KFO95974.1 - 0.041 12.5 0.0 0.069 11.8 0.0 1.4 1 0 0 1 1 1 0 FAM198 protein Dynein_light PF01221.13 KFO95975.1 - 8.6e-29 99.3 0.2 9.9e-29 99.1 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3109 PF11307.3 KFO95975.1 - 0.032 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) GARS_A PF01071.14 KFO95975.1 - 0.051 13.1 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pentaxin PF00354.12 KFO95976.1 - 6.4e-37 126.8 0.0 9e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFO95976.1 - 2.6e-13 50.5 0.0 4.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Chromo PF00385.19 KFO95977.1 - 4.2e-11 42.3 1.0 4.2e-11 42.3 0.7 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PDGF PF00341.12 KFO95978.1 - 1.3e-22 79.6 12.4 2.6e-22 78.7 8.6 1.5 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.8 KFO95978.1 - 1.9e-19 69.8 2.6 4.7e-19 68.6 0.1 2.4 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region Ribosomal_L3 PF00297.17 KFO95979.1 - 1.1e-123 411.7 9.9 1.3e-123 411.5 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3903 PF13043.1 KFO95979.1 - 0.041 13.3 1.0 0.17 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) Glyco_transf_17 PF04724.8 KFO95981.1 - 7.3e-131 436.3 0.0 9.3e-131 436.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 hEGF PF12661.2 KFO95981.1 - 0.0061 16.5 3.7 0.021 14.8 2.5 2.0 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 KFO95981.1 - 0.14 12.3 1.0 0.33 11.1 0.7 1.6 1 0 0 1 1 1 0 EGF-like domain Mab-21 PF03281.9 KFO95982.1 - 6.7e-33 114.0 0.0 1.8e-30 106.0 0.0 2.1 1 1 0 1 1 1 1 Mab-21 protein bZIP_1 PF00170.16 KFO95983.1 - 3.3e-14 52.5 14.2 3.3e-14 52.5 9.9 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFO95983.1 - 3.4e-08 33.1 11.7 7.1e-08 32.1 8.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper IncA PF04156.9 KFO95983.1 - 0.0045 16.6 6.2 0.0073 15.9 4.3 1.2 1 0 0 1 1 1 1 IncA protein BLOC1_2 PF10046.4 KFO95983.1 - 0.15 12.1 4.9 0.34 11.0 3.4 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPO PF05929.6 KFO95983.1 - 0.24 10.5 4.2 0.45 9.7 2.9 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Laminin_II PF06009.7 KFO95983.1 - 0.29 10.8 6.9 0.51 10.1 4.8 1.3 1 0 0 1 1 1 0 Laminin Domain II bZIP_Maf PF03131.12 KFO95983.1 - 0.38 11.0 9.3 0.67 10.2 6.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6 PF04111.7 KFO95983.1 - 1.8 7.5 10.2 2.6 7.0 7.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KFO95983.1 - 6.1 4.5 6.6 8.4 4.1 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ion_trans PF00520.26 KFO95985.1 - 2.6e-202 666.6 85.5 7.6e-64 214.6 10.2 4.4 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 KFO95985.1 - 3.9e-13 48.6 84.0 9.8e-08 30.8 2.4 9.7 6 3 2 8 8 8 6 Polycystin cation channel FimP PF09766.4 KFO95985.1 - 0.00071 18.7 0.1 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Fms-interacting protein EphA2_TM PF14575.1 KFO95985.1 - 0.023 15.0 1.3 25 5.3 0.1 4.3 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_L41 PF05162.8 KFO95985.1 - 2.1 8.0 9.3 4.5 7.0 6.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L41 DUF1669 PF07894.7 KFO95986.1 - 2.2e-87 292.8 0.0 3.4e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFO95986.1 - 2e-07 30.8 0.0 3.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain DUF572 PF04502.8 KFO95986.1 - 0.03 13.5 0.1 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1465 PF07323.7 KFO95986.1 - 0.066 12.7 0.7 0.25 10.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DUF3006 PF11213.3 KFO95986.1 - 0.098 12.4 0.2 0.46 10.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3006) Lyase_1 PF00206.15 KFO95987.1 - 1.4e-25 90.1 0.0 2.1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KFO95987.1 - 9.2e-16 57.6 0.0 2.8e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.1 KFO95987.1 - 9.5e-05 22.6 0.3 0.00036 20.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4089) DUF1331 PF07048.6 KFO95987.1 - 0.046 13.1 0.1 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) RabGAP-TBC PF00566.13 KFO95988.1 - 1.8e-36 125.6 0.3 3.3e-36 124.7 0.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RUN PF02759.14 KFO95988.1 - 1.3e-30 105.8 0.2 2.5e-30 104.9 0.1 1.5 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.23 KFO95988.1 - 3e-12 45.7 0.1 7.5e-12 44.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFO95988.1 - 7.9e-11 41.3 0.1 2.8e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFO95988.1 - 4.6e-10 38.8 0.0 1.2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain RPEL PF02755.10 KFO95989.1 - 8.7e-27 91.6 12.4 6.2e-09 34.9 0.0 3.8 4 0 0 4 4 4 3 RPEL repeat SAP PF02037.22 KFO95989.1 - 6.3e-10 38.3 0.5 2e-09 36.7 0.4 2.0 1 0 0 1 1 1 1 SAP domain TMEM52 PF14979.1 KFO95989.1 - 0.04 13.8 0.2 0.04 13.8 0.2 2.5 2 0 0 2 2 2 0 Transmembrane 52 Mito_carr PF00153.22 KFO95990.1 - 1.5e-53 178.4 0.5 4e-23 80.9 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Peptidase_M24 PF00557.19 KFO95991.1 - 2.3e-55 187.3 0.0 3.1e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFO95991.1 - 5.9e-37 126.0 0.0 1.2e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Tax PF02959.11 KFO95991.1 - 0.084 12.3 0.0 14 5.0 0.0 2.4 2 0 0 2 2 2 0 HTLV Tax zf-rbx1 PF12678.2 KFO95992.1 - 3e-33 113.7 14.5 3.4e-33 113.5 10.0 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFO95992.1 - 8.7e-16 57.5 10.7 1e-15 57.2 7.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFO95992.1 - 5.4e-08 32.5 12.4 4.3e-07 29.6 8.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFO95992.1 - 0.00032 20.3 12.2 0.0069 16.0 8.5 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO95992.1 - 0.00051 19.6 10.3 0.0026 17.3 3.2 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO95992.1 - 0.0077 16.2 12.6 0.019 14.9 5.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFO95992.1 - 0.11 12.4 9.4 0.69 9.9 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KFO95992.1 - 0.18 11.5 6.8 0.66 9.7 2.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 KFO95992.1 - 0.21 11.3 12.9 2.4 7.9 9.0 2.5 1 1 0 1 1 1 0 zinc-RING finger domain DUF4001 PF13165.1 KFO95992.1 - 0.41 10.3 5.0 0.59 9.8 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) zf-RING_6 PF14835.1 KFO95992.1 - 1.6 8.5 5.5 0.71 9.7 0.2 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-HC5HC2H_2 PF13832.1 KFO95992.1 - 1.9 8.5 11.4 5.4 7.0 7.9 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFO95992.1 - 4.5 7.4 12.5 3.2e+02 1.5 8.8 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 KFO95992.1 - 8.8 6.3 9.9 0.49 10.3 0.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DoxX_2 PF13564.1 KFO95993.1 - 2.7 7.9 9.5 0.25 11.3 3.1 1.8 2 1 0 2 2 2 0 DoxX-like family LRR_8 PF13855.1 KFO95994.1 - 2.9e-38 129.4 4.4 1.5e-16 59.9 0.1 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFO95994.1 - 1e-14 53.7 2.9 0.0001 21.8 0.0 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO95994.1 - 3e-13 47.8 0.4 0.21 11.7 0.0 5.0 4 1 1 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 KFO95994.1 - 1.3e-07 30.6 6.1 0.44 10.9 0.1 4.9 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KFO95994.1 - 2.5e-05 23.9 0.1 0.27 11.4 0.0 4.1 4 1 0 4 4 4 1 Leucine Rich repeat LRR_5 PF13306.1 KFO95994.1 - 0.003 17.2 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFO95994.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.6 1 1 0 1 1 1 0 Leucine-rich repeat Xan_ur_permease PF00860.15 KFO95995.1 - 2.7e-89 299.4 23.3 3.8e-89 298.9 16.2 1.1 1 0 0 1 1 1 1 Permease family WD40 PF00400.27 KFO95996.1 - 2.3e-20 71.6 9.2 3.2e-05 23.6 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KFO95996.1 - 0.011 15.9 0.0 54 4.2 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain MMS1_N PF10433.4 KFO95996.1 - 0.032 12.3 0.0 0.18 9.9 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term TM140 PF14985.1 KFO95997.1 - 6e-20 71.6 0.4 6.8e-20 71.4 0.3 1.1 1 0 0 1 1 1 1 TM140 protein family Peptidase_M14 PF00246.19 KFO95998.1 - 6.4e-31 107.9 0.0 1.1e-30 107.1 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KFO95998.1 - 0.0013 17.6 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PDE6_gamma PF04868.7 KFO95999.1 - 5.4e-48 160.7 0.9 5.9e-48 160.6 0.6 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit Rho_GDI PF02115.12 KFO96000.1 - 4.9e-91 303.5 0.3 5.3e-91 303.4 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4316 PF14195.1 KFO96000.1 - 0.032 14.3 0.1 0.055 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Thioredoxin_6 PF13848.1 KFO96001.1 - 2.3e-22 79.7 0.2 2.8e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Gla PF00594.15 KFO96002.1 - 8.2e-12 44.6 7.5 8.7e-12 44.5 3.2 2.0 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain ODV-E18 PF10717.4 KFO96002.1 - 0.05 13.0 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Gla PF00594.15 KFO96003.1 - 5.9e-09 35.4 0.2 8.4e-09 34.9 0.1 1.3 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain zf-C4_Topoisom PF01396.14 KFO96003.1 - 0.73 9.3 2.9 0.62 9.6 0.9 1.7 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger ART PF01129.13 KFO96004.1 - 4.9e-51 172.9 2.6 5.5e-51 172.7 1.8 1.0 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.9 KFO96004.1 - 0.00022 20.4 0.0 0.00034 19.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme SGT1 PF07093.6 KFO96004.1 - 0.0025 16.2 0.2 0.0027 16.1 0.1 1.1 1 0 0 1 1 1 1 SGT1 protein DUF4533 PF15047.1 KFO96005.1 - 5.7e-14 52.0 0.8 6.5e-14 51.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) DUF4533 PF15047.1 KFO96006.1 - 1.1e-81 273.5 6.5 1.3e-81 273.3 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) DNA_repr_REX1B PF14966.1 KFO96006.1 - 0.0045 17.3 2.3 0.034 14.4 0.3 2.3 2 0 0 2 2 2 1 DNA repair REX1-B EIF4E-T PF10477.4 KFO96006.1 - 0.064 12.0 0.1 0.082 11.6 0.1 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF2408 PF10303.4 KFO96006.1 - 0.66 10.0 4.5 1.3 9.1 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Wbp11 PF09429.5 KFO96007.1 - 9.2e-22 76.8 15.0 9.2e-22 76.8 10.4 3.2 3 1 0 3 3 3 1 WW domain binding protein 11 TFIIA PF03153.8 KFO96007.1 - 0.0034 17.3 1.7 0.0034 17.3 1.2 3.1 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit Histone PF00125.19 KFO96008.1 - 2.9e-27 94.6 0.0 3.7e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96008.1 - 2.8e-05 24.1 0.0 3.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Linker_histone PF00538.14 KFO96009.1 - 1.1e-21 76.6 3.5 2.9e-21 75.3 2.4 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family Histone PF00125.19 KFO96010.1 - 4.9e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96010.1 - 9.5e-07 28.7 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFO96010.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFO96010.1 - 0.038 13.4 0.2 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFO96011.1 - 5.2e-15 55.3 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFO96011.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFO96011.1 - 3.1e-05 23.8 0.2 4.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFO96011.1 - 0.00021 21.2 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFO96011.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFO96011.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFO96011.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KFO96013.1 - 9.1e-21 73.7 0.0 1.2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96013.1 - 0.03 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFO96014.1 - 4.3e-26 90.8 0.1 6e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96014.1 - 1.2e-06 28.4 1.2 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFO96014.1 - 0.0028 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFO96014.1 - 0.059 12.8 0.2 0.094 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFO96015.1 - 3e-32 110.5 0.5 3.3e-32 110.4 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFO96015.1 - 7.1e-05 22.9 0.0 9.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFO96015.1 - 0.0042 17.1 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KFO96015.1 - 0.0066 15.7 0.1 0.0072 15.6 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Histone PF00125.19 KFO96016.1 - 2.2e-27 94.9 0.0 2.8e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96016.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFO96017.1 - 2.7e-26 91.4 0.1 3.7e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96017.1 - 1e-06 28.6 0.5 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFO96017.1 - 0.0024 18.1 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFO96017.1 - 0.039 13.3 0.2 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Linker_histone PF00538.14 KFO96018.1 - 1.1e-20 73.4 3.5 2.5e-20 72.3 2.4 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Mitofilin PF09731.4 KFO96018.1 - 0.59 8.7 24.9 0.61 8.6 17.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Asp-B-Hydro_N PF05279.6 KFO96018.1 - 1.1 8.9 7.6 1.3 8.8 5.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Herpes_UL32 PF06070.6 KFO96018.1 - 1.9 6.8 17.9 2.1 6.7 12.4 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 CDC27 PF09507.5 KFO96018.1 - 7.1 5.7 34.7 9.8 5.2 24.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Histone PF00125.19 KFO96019.1 - 4e-15 55.6 0.1 4.9e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFO96019.1 - 1.4e-05 25.1 0.1 1.8e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFO96019.1 - 2.5e-05 24.1 0.2 3.4e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFO96019.1 - 0.00018 21.5 0.1 0.00027 20.9 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KFO96019.1 - 0.014 14.6 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KFO96019.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 KFO96019.1 - 0.049 13.4 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KFO96021.1 - 5.9e-31 106.4 0.4 6.9e-31 106.2 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFO96021.1 - 5.3e-05 23.3 0.0 6.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFO96021.1 - 0.006 16.6 0.0 0.0074 16.3 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KFO96021.1 - 0.0068 15.7 0.0 0.0079 15.4 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Histone PF00125.19 KFO96022.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFO96022.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFO96022.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KFO96022.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KFO96023.1 - 5.2e-15 55.3 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFO96023.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFO96023.1 - 3.1e-05 23.8 0.2 4.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFO96023.1 - 0.00021 21.2 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFO96023.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFO96023.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFO96023.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KFO96025.1 - 4.1e-27 94.1 0.0 5.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96025.1 - 3.7e-05 23.6 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFO96026.1 - 3.9e-26 90.9 0.1 5.3e-26 90.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96026.1 - 1.1e-06 28.6 0.7 1.8e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFO96026.1 - 0.0022 18.2 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFO96026.1 - 0.035 13.5 0.2 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Histone PF00125.19 KFO96027.1 - 1.5e-12 47.4 0.2 2e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Linker_histone PF00538.14 KFO96028.1 - 1.7e-21 76.1 1.8 1.7e-21 76.1 1.3 2.3 2 0 0 2 2 2 1 linker histone H1 and H5 family Histone PF00125.19 KFO96029.1 - 8.4e-16 57.8 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.19 KFO96030.1 - 8.4e-16 57.8 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Linker_histone PF00538.14 KFO96031.1 - 1.6e-12 47.3 2.5 1.6e-12 47.3 1.7 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family ApoL PF05461.6 KFO96032.1 - 5.8e-20 71.7 0.8 5.8e-20 71.7 0.5 1.7 2 0 0 2 2 2 1 Apolipoprotein L SseC PF04888.7 KFO96032.1 - 6e-06 25.8 0.5 0.00015 21.2 0.2 2.0 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Serum_albumin PF00273.15 KFO96032.1 - 0.0089 15.4 1.6 0.016 14.6 1.1 1.3 1 1 0 1 1 1 1 Serum albumin family VIT1 PF01988.14 KFO96032.1 - 0.031 13.7 1.8 0.056 12.9 1.3 1.4 1 0 0 1 1 1 0 VIT family Prefoldin PF02996.12 KFO96032.1 - 0.21 11.2 2.1 6.9 6.3 0.0 2.6 3 0 0 3 3 3 0 Prefoldin subunit DUF4231 PF14015.1 KFO96032.1 - 0.24 11.4 2.1 0.43 10.5 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DEAD PF00270.24 KFO96033.1 - 3.2e-46 156.9 0.2 5.2e-46 156.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO96033.1 - 1.8e-28 98.1 0.2 1.9e-27 94.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFO96033.1 - 0.00032 20.5 0.0 0.00098 19.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ICAM_N PF03921.9 KFO96033.1 - 0.13 11.7 0.2 2.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain 7tm_3 PF00003.17 KFO96034.1 - 2e-34 118.9 29.4 2.4e-34 118.7 20.4 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF1772 PF08592.6 KFO96034.1 - 0.077 12.7 0.2 0.077 12.7 0.2 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) Tmpp129 PF10272.4 KFO96034.1 - 0.11 11.2 2.8 0.16 10.6 2.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF1345 PF07077.6 KFO96034.1 - 0.19 11.2 11.6 1.4 8.4 5.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) DUF1129 PF06570.6 KFO96034.1 - 0.72 9.1 20.4 0.11 11.7 3.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) SOUL PF04832.7 KFO96035.1 - 4.8e-44 149.9 0.0 5.4e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein FlaC_arch PF05377.6 KFO96036.1 - 0.049 13.5 0.1 0.097 12.5 0.1 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PQQ_2 PF13360.1 KFO96037.1 - 2.5e-07 30.4 0.0 0.0043 16.5 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain FG-GAP PF01839.18 KFO96037.1 - 5.4e-07 29.1 3.3 0.002 17.7 0.0 2.9 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.1 KFO96037.1 - 5.3e-06 26.6 0.2 0.084 13.2 0.0 3.3 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 KFO96037.1 - 0.069 12.5 0.1 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region GSG-1 PF07803.6 KFO96038.1 - 3.8e-48 161.9 0.1 1e-47 160.5 0.0 1.7 2 0 0 2 2 2 1 GSG1-like protein Claudin_2 PF13903.1 KFO96038.1 - 1.7e-10 40.8 0.5 3.3e-10 39.9 0.3 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFO96038.1 - 1.8e-07 30.9 7.0 2.2e-07 30.6 1.9 2.4 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.7 KFO96038.1 - 0.84 8.8 12.3 1 8.5 0.0 2.7 3 1 0 3 3 3 0 Clc-like PMP22_Claudin PF00822.15 KFO96039.1 - 1.6e-44 151.4 20.3 1.9e-44 151.2 14.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO96039.1 - 1.9e-06 27.6 15.7 1.9e-06 27.6 10.9 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 KFO96039.1 - 0.052 13.6 19.5 0.24 11.5 7.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Amastin PF07344.6 KFO96039.1 - 0.079 12.5 22.1 0.17 11.4 14.5 1.9 1 1 0 1 1 1 0 Amastin surface glycoprotein Claudin_3 PF06653.6 KFO96039.1 - 0.17 11.6 23.4 0.31 10.7 16.2 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF3483 PF11982.3 KFO96039.1 - 0.41 9.8 2.4 0.49 9.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) 7TMR-DISM_7TM PF07695.6 KFO96039.1 - 1 9.0 29.1 18 4.9 19.0 3.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF998 PF06197.8 KFO96039.1 - 4.3 6.6 14.8 0.17 11.2 4.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF998) NMDAR2_C PF10565.4 KFO96040.1 - 1.1e-255 850.5 17.3 1.3e-255 850.3 12.0 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.21 KFO96040.1 - 1.2e-34 119.1 0.1 2e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFO96040.1 - 2.4e-27 95.6 0.0 4.1e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFO96040.1 - 2.5e-20 72.2 0.3 5e-20 71.2 0.2 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 KFO96040.1 - 2.1e-07 30.0 0.1 4.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region Phospholip_B PF04916.8 KFO96042.1 - 7.1e-166 552.5 1.7 9.5e-166 552.1 1.2 1.1 1 0 0 1 1 1 1 Phospholipase B Guanylate_cyc PF00211.15 KFO96043.1 - 2.2e-65 219.4 0.0 3.9e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 KFO96043.1 - 3e-35 121.5 0.0 7.5e-35 120.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase ANF_receptor PF01094.23 KFO96043.1 - 5.1e-30 104.4 0.0 7.3e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.20 KFO96043.1 - 7.1e-29 100.7 0.2 2.5e-28 98.9 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Rifin_STEVOR PF02009.11 KFO96043.1 - 0.44 10.1 4.6 1 8.9 3.2 1.5 1 0 0 1 1 1 0 Rifin/stevor family TPR_19 PF14559.1 KFO96044.1 - 9.3e-20 70.7 13.1 8.8e-06 25.9 0.0 5.8 5 1 2 7 7 6 5 Tetratricopeptide repeat Apc3 PF12895.2 KFO96044.1 - 1.1e-15 57.5 22.0 0.00095 19.2 0.4 5.9 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KFO96044.1 - 3.1e-11 43.6 6.0 0.0079 16.8 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFO96044.1 - 5.9e-11 41.4 26.7 0.03 14.2 0.1 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96044.1 - 2.2e-10 40.2 6.7 0.37 11.5 0.0 6.6 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFO96044.1 - 2.9e-10 39.6 20.6 6.5e-08 32.1 0.0 5.5 5 2 1 6 6 6 2 TPR repeat TPR_17 PF13431.1 KFO96044.1 - 2.9e-07 30.1 8.8 0.00059 19.8 0.0 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO96044.1 - 5e-07 29.7 13.7 0.43 11.1 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFO96044.1 - 2e-06 27.1 18.2 0.0053 16.3 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFO96044.1 - 6.2e-06 25.6 9.9 0.18 11.6 0.0 7.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFO96044.1 - 1.1e-05 25.3 19.3 0.012 15.5 0.2 7.5 5 3 1 6 6 6 2 Tetratricopeptide repeat PPR PF01535.15 KFO96044.1 - 9.1e-05 22.1 0.5 0.38 10.8 0.0 4.5 5 0 0 5 5 4 1 PPR repeat TPR_9 PF13371.1 KFO96044.1 - 0.00017 21.3 4.2 0.038 13.8 0.4 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFO96044.1 - 0.00028 20.4 7.6 3.1 7.8 0.1 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat PPR_2 PF13041.1 KFO96044.1 - 0.00036 20.4 0.6 1.1 9.3 0.1 4.1 4 1 1 5 5 4 1 PPR repeat family TPR_4 PF07721.9 KFO96044.1 - 0.0011 19.1 0.0 23 5.7 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Glyco_trans_1_3 PF13528.1 KFO96044.1 - 0.017 14.3 0.0 0.039 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 1 Fis1_TPR_C PF14853.1 KFO96044.1 - 0.05 13.4 5.1 1.8 8.4 0.2 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 KFO96044.1 - 0.63 10.0 8.3 35 4.4 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat UBN_AB PF14075.1 KFO96045.1 - 3.1e-82 275.4 3.3 3.1e-82 275.4 2.3 2.2 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.5 KFO96045.1 - 1.7e-20 72.6 0.4 4.4e-20 71.2 0.3 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Proho_convert PF12177.3 KFO96045.1 - 0.028 14.0 0.1 0.066 12.7 0.1 1.6 1 0 0 1 1 1 0 Prohormone convertase enzyme Complex1_LYR_2 PF13233.1 KFO96046.1 - 0.0002 21.7 0.2 0.00027 21.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like LUC7 PF03194.10 KFO96047.1 - 3e-78 262.8 36.5 2.2e-77 260.0 25.2 2.5 1 1 0 1 1 1 1 LUC7 N_terminus Globin PF00042.17 KFO96048.1 - 2.5e-31 108.2 0.3 3.9e-31 107.6 0.1 1.4 2 0 0 2 2 2 1 Globin DUF3799 PF12684.2 KFO96048.1 - 0.025 13.9 0.4 0.027 13.8 0.3 1.1 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Poty_PP PF08440.5 KFO96048.1 - 0.052 12.5 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein Imm15 PF15590.1 KFO96048.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 15 Anthrax-tox_M PF09156.5 KFO96049.1 - 0.017 14.2 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain RRM_1 PF00076.17 KFO96050.1 - 2.9e-10 39.6 0.0 7.4e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96050.1 - 8.9e-09 35.2 0.0 2.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96050.1 - 6.5e-07 29.1 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 PF12923.2 KFO96051.1 - 6.3e-43 145.9 10.0 9.4e-43 145.3 6.9 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 KFO96051.1 - 0.026 14.1 0.4 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trans_reg_C PF00486.23 KFO96051.1 - 0.033 14.1 1.3 0.28 11.1 0.4 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DNA_pol_A PF00476.15 KFO96051.1 - 0.037 12.6 0.6 0.047 12.3 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase family A Phage_GP20 PF06810.6 KFO96051.1 - 0.072 12.5 0.3 0.072 12.5 0.2 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.4 KFO96051.1 - 0.3 10.0 4.2 0.4 9.5 2.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Abhydrolase_6 PF12697.2 KFO96052.1 - 2.8e-31 109.1 0.2 3.5e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO96052.1 - 6.3e-18 65.1 0.0 1.3e-17 64.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFO96052.1 - 2.3e-10 40.4 0.0 3.7e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFO96052.1 - 2e-05 24.3 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 KFO96052.1 - 0.0052 16.3 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 KFO96052.1 - 0.0086 16.3 0.5 0.068 13.3 0.1 2.2 2 1 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 KFO96052.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein SH2 PF00017.19 KFO96053.1 - 2.5e-06 27.2 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 SH2 domain zf-HC5HC2H PF13771.1 KFO96055.1 - 1.4e-11 44.3 5.6 3.9e-11 42.9 3.9 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFO96055.1 - 1.3e-07 31.6 2.0 3.6e-07 30.1 1.4 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain p450 PF00067.17 KFO96056.1 - 7.5e-124 413.7 0.1 2.8e-123 411.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Complex1_LYR PF05347.10 KFO96057.1 - 3.7e-06 26.6 0.0 5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFO96057.1 - 0.00036 20.6 0.0 0.00056 20.0 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like PH PF00169.24 KFO96058.1 - 3.2e-14 52.9 0.0 4.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFO96058.1 - 1.3e-05 25.2 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFO96058.1 - 5.4e-05 23.4 0.0 0.0073 16.5 0.1 2.3 1 1 1 2 2 2 1 Pleckstrin homology domain AAA_32 PF13654.1 KFO96058.1 - 0.024 13.2 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain PH_7 PF15408.1 KFO96058.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain ASCH PF04266.9 KFO96058.1 - 0.1 13.0 0.1 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 ASCH domain Melibiase PF02065.13 KFO96059.1 - 1.4e-14 53.6 0.0 9.3e-14 50.9 0.0 2.0 1 1 1 2 2 2 1 Melibiase Glyco_hydro_97 PF10566.4 KFO96059.1 - 0.00018 20.7 0.0 0.0014 17.7 0.0 1.9 2 0 0 2 2 2 1 Glycoside hydrolase 97 WWbp PF10349.4 KFO96060.1 - 3.4e-18 66.6 26.0 3.4e-18 66.6 18.0 2.2 1 1 1 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 KFO96060.1 - 1.5e-09 37.2 0.1 2.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Septin PF00735.13 KFO96061.1 - 8.4e-116 385.9 1.7 9.7e-116 385.6 1.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFO96061.1 - 2.3e-08 34.0 0.2 4.1e-08 33.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFO96061.1 - 8.3e-07 28.3 0.5 1.9e-06 27.1 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFO96061.1 - 3e-05 23.2 0.1 5.6e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KFO96061.1 - 5.2e-05 22.7 0.4 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFO96061.1 - 0.00017 21.4 7.9 0.029 14.1 0.6 3.3 2 2 2 4 4 4 2 Dynamin family FtsK_SpoIIIE PF01580.13 KFO96061.1 - 0.00023 20.6 0.3 0.0016 17.9 0.1 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KFO96061.1 - 0.00029 20.3 0.2 0.00031 20.2 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 KFO96061.1 - 0.00062 20.2 0.9 0.0023 18.3 0.6 2.1 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 KFO96061.1 - 0.00096 19.4 0.2 0.0035 17.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Ras PF00071.17 KFO96061.1 - 0.0036 16.7 0.2 0.011 15.1 0.1 1.9 1 1 0 2 2 2 1 Ras family AAA_16 PF13191.1 KFO96061.1 - 0.0036 17.2 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFO96061.1 - 0.0058 16.7 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KFO96061.1 - 0.0069 15.8 0.1 0.54 9.7 0.0 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KFO96061.1 - 0.015 14.8 0.1 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 KFO96061.1 - 0.02 13.5 0.0 0.044 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFO96061.1 - 0.028 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 KFO96061.1 - 0.036 12.9 1.1 0.043 12.6 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain IIGP PF05049.8 KFO96061.1 - 0.038 12.8 0.8 0.073 11.8 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 KFO96061.1 - 0.043 13.1 0.1 0.09 12.0 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B KAP_NTPase PF07693.9 KFO96061.1 - 0.044 12.7 0.1 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.9 KFO96061.1 - 0.053 13.2 0.4 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KFO96061.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFO96061.1 - 0.086 12.7 0.1 0.36 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KFO96061.1 - 0.091 11.6 0.1 0.17 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KFO96061.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 KFO96061.1 - 0.11 12.2 1.1 0.23 11.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 CENP-M PF11111.3 KFO96062.1 - 8.3e-52 174.9 0.3 9.2e-52 174.8 0.2 1.0 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Pox_I5 PF04713.7 KFO96062.1 - 0.094 12.4 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Poxvirus protein I5 BaffR-Tall_bind PF09256.5 KFO96063.1 - 0.0001 21.8 2.4 0.00021 20.8 1.7 1.6 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding COX16 PF14138.1 KFO96063.1 - 0.061 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Shisa PF13908.1 KFO96064.1 - 2e-38 132.3 2.4 2.1e-38 132.2 1.7 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.6 KFO96064.1 - 0.06 13.2 0.3 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF2970 PF11174.3 KFO96064.1 - 0.086 12.4 0.1 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) HLH PF00010.21 KFO96065.1 - 2.3e-16 59.1 0.7 5.5e-16 58.0 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ERK-JNK_inhib PF15002.1 KFO96066.1 - 1.3e-51 174.9 0.1 1.5e-51 174.7 0.1 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor Med28 PF11594.3 KFO96066.1 - 0.021 15.0 0.8 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 28 Ribosomal_L7Ae PF01248.21 KFO96068.1 - 9.2e-26 89.1 0.1 1.1e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KFO96068.1 - 0.00025 20.8 0.1 0.00029 20.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KFO96068.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Ku_N PF03731.10 KFO96069.1 - 3e-68 229.6 0.1 5.1e-68 228.8 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 KFO96069.1 - 8.7e-59 198.2 1.0 2.1e-58 197.0 0.1 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 KFO96069.1 - 8.8e-23 80.6 0.2 3.7e-22 78.6 0.2 2.2 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KFO96069.1 - 1.5e-10 40.3 0.1 3e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 SAP domain Peptidase_C97 PF05903.9 KFO96070.1 - 2e-35 121.8 0.0 2.3e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PMM PF03332.8 KFO96071.1 - 1.7e-110 367.8 0.1 1.9e-110 367.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase CSD PF00313.17 KFO96072.1 - 1.5e-13 50.3 0.1 2e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KFO96072.1 - 0.0004 19.8 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain RNA_pol_Rbc25 PF08292.7 KFO96073.1 - 1.7e-45 154.1 0.1 2.7e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KFO96073.1 - 3.2e-20 72.0 0.1 6.3e-20 71.0 0.0 1.5 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Aconitase PF00330.15 KFO96074.1 - 1.1e-183 610.9 0.0 2.1e-183 610.0 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFO96074.1 - 5.2e-47 159.2 0.0 1e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PHF5 PF03660.9 KFO96075.1 - 1.3e-37 128.0 14.0 1.5e-37 127.9 9.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 KFO96075.1 - 0.044 11.4 3.7 0.047 11.3 2.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 BTG PF07742.7 KFO96076.1 - 2.1e-40 136.9 0.0 3e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 BTG family PAM2 PF07145.10 KFO96076.1 - 1.1e-12 46.5 4.2 4.8e-06 25.7 0.0 3.7 4 0 0 4 4 4 2 Ataxin-2 C-terminal region bZIP_2 PF07716.10 KFO96077.1 - 7.5e-16 57.6 11.6 7.5e-16 57.6 8.0 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KFO96077.1 - 3.9e-06 26.7 8.5 7.2e-06 25.8 5.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Microtub_assoc PF07989.6 KFO96077.1 - 0.03 14.1 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Microtubule associated bZIP_Maf PF03131.12 KFO96077.1 - 0.031 14.5 5.4 0.074 13.3 3.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.6 KFO96077.1 - 0.041 13.7 0.2 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 KFO96077.1 - 0.053 13.2 0.1 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper COesterase PF00135.23 KFO96078.1 - 2.8e-118 395.9 0.0 3.6e-118 395.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Sarcoglycan_2 PF05510.8 KFO96078.1 - 0.0016 16.8 0.1 0.0035 15.6 0.1 1.5 2 0 0 2 2 2 1 Sarcoglycan alpha/epsilon Abhydrolase_3 PF07859.8 KFO96078.1 - 0.02 14.4 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3328 PF11807.3 KFO96080.1 - 0.046 13.4 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Peptidase_M28 PF04389.12 KFO96081.1 - 2.4e-07 30.6 0.0 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.10 KFO96081.1 - 3.6e-05 23.3 0.0 8.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain WD40 PF00400.27 KFO96082.1 - 2.3e-70 230.1 25.1 3.3e-13 48.9 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KFO96082.1 - 3.1e-12 46.6 0.7 0.00086 19.0 0.1 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 KFO96082.1 - 2.7e-10 39.6 0.1 1.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 LisH Apc4_WD40 PF12894.2 KFO96082.1 - 3.6e-05 23.1 0.0 6.3 6.3 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 KFO96082.1 - 0.00089 18.1 0.0 0.02 13.7 0.0 2.3 2 0 0 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 KFO96082.1 - 0.0046 15.1 4.4 0.31 9.1 0.1 3.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 TSP9 PF11493.3 KFO96082.1 - 0.0096 16.4 0.2 0.02 15.4 0.1 1.4 1 0 0 1 1 1 1 Thylakoid soluble phosphoprotein TSP9 IKI3 PF04762.7 KFO96082.1 - 0.016 13.0 0.5 0.21 9.3 0.4 2.5 1 1 0 1 1 1 0 IKI3 family CaKB PF03185.10 KFO96083.1 - 1.4e-91 305.3 8.5 1.6e-91 305.1 5.9 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit KcnmB2_inactiv PF09303.5 KFO96083.1 - 1.4e-06 27.9 2.9 2.9e-06 26.9 2.0 1.6 1 0 0 1 1 1 1 KCNMB2, ball and chain domain tRNA-synt_1g PF09334.6 KFO96083.1 - 0.058 12.0 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Pox_A9 PF04835.7 KFO96083.1 - 1.6 8.7 5.0 1.3 9.0 1.7 2.1 2 0 0 2 2 2 0 A9 protein conserved region zf-met PF12874.2 KFO96084.1 - 2e-23 81.7 15.8 7.3e-09 35.5 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO96084.1 - 1.5e-19 69.5 17.1 5.6e-07 29.5 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFO96084.1 - 2.6e-09 37.0 11.7 0.011 15.7 0.3 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFO96084.1 - 0.00073 19.0 18.3 0.083 12.4 2.1 3.6 3 1 0 3 3 3 2 U1 zinc finger AKAP95 PF04988.7 KFO96084.1 - 0.0038 17.0 8.4 0.012 15.3 0.3 2.9 3 0 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 KFO96084.1 - 0.0063 16.7 10.6 1.1 9.7 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-DBF PF07535.7 KFO96084.1 - 2 8.1 7.7 2 8.1 0.3 2.9 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.21 KFO96085.1 - 2.3e-16 59.0 60.8 0.0037 17.5 0.7 9.7 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96085.1 - 7.5e-15 54.0 52.0 0.0084 16.3 0.3 9.6 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO96085.1 - 4.4e-13 48.7 55.6 5e-05 23.3 0.1 10.0 10 0 0 10 10 10 6 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFO96085.1 - 5.7e-10 38.8 55.6 0.0017 18.4 1.2 8.9 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KFO96085.1 - 0.0025 17.6 4.4 0.04 13.8 0.3 6.9 8 0 0 8 8 8 4 C2H2-type zinc finger CarbpepA_inh PF02977.10 KFO96085.1 - 1.5 8.5 15.2 1.5 8.4 0.0 5.1 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor zf-C2H2_2 PF12756.2 KFO96085.1 - 2.3 8.3 50.9 6.8 6.8 9.8 5.9 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Fzo_mitofusin PF04799.8 KFO96086.1 - 3e-79 264.3 5.0 3e-79 264.3 3.5 2.7 2 1 0 2 2 2 1 fzo-like conserved region Dynamin_N PF00350.18 KFO96086.1 - 1.8e-23 83.1 0.0 1.8e-23 83.1 0.0 3.7 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KFO96086.1 - 6.1e-07 29.4 0.6 2.5e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Apolipoprotein PF01442.13 KFO96086.1 - 0.0039 16.7 17.4 0.082 12.4 3.9 3.2 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain AAA_29 PF13555.1 KFO96086.1 - 0.082 12.4 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Hydantoinase_A PF01968.13 KFO96086.1 - 0.091 11.8 0.0 0.21 10.6 0.0 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase AAA_23 PF13476.1 KFO96086.1 - 0.16 12.2 17.1 1.2 9.3 0.2 3.9 3 1 0 3 3 3 0 AAA domain DUF1664 PF07889.7 KFO96086.1 - 9.6 6.0 11.5 0.31 10.8 0.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.27 KFO96087.1 - 9.3e-55 180.6 26.4 1.4e-09 37.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFO96087.1 - 6.6e-05 22.6 0.0 0.23 11.1 0.0 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A UL11 PF11094.3 KFO96087.1 - 0.0075 16.0 1.0 0.021 14.6 0.2 2.1 2 0 0 2 2 2 1 Membrane-associated tegument protein Nucleoporin_N PF08801.6 KFO96087.1 - 0.021 13.5 1.0 1.6 7.3 0.1 3.1 3 1 0 3 3 3 0 Nup133 N terminal like Actin PF00022.14 KFO96088.1 - 6.6e-111 370.4 0.0 1.1e-93 313.7 0.0 2.0 1 1 1 2 2 2 2 Actin MobA_MobL PF03389.10 KFO96088.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 MobA/MobL family MRP-L47 PF06984.8 KFO96089.1 - 3.4e-35 119.7 1.1 3.4e-35 119.7 0.7 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NDUF_B5 PF09781.4 KFO96090.1 - 1.3e-79 265.8 0.5 1.4e-79 265.7 0.4 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit TPR_1 PF00515.23 KFO96091.1 - 1e-25 88.2 1.8 1.7e-05 24.2 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFO96091.1 - 2.5e-24 84.7 6.5 3.3e-11 42.6 0.0 4.3 2 2 3 5 5 5 5 TPR repeat TPR_2 PF07719.12 KFO96091.1 - 5.5e-21 72.7 7.9 0.00018 21.1 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFO96091.1 - 9.5e-18 62.8 9.5 0.0008 19.4 0.3 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFO96091.1 - 1.8e-15 57.1 5.3 4.1e-06 27.3 0.2 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96091.1 - 2.3e-14 52.5 11.2 0.0011 19.4 0.7 6.2 3 2 3 6 6 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFO96091.1 - 3.4e-13 49.7 7.2 0.00044 20.5 1.8 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFO96091.1 - 5e-11 42.3 2.2 0.00043 20.0 0.3 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO96091.1 - 6.3e-10 38.8 1.1 9.7e-06 25.4 0.2 3.8 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFO96091.1 - 1.8e-09 36.7 1.1 0.34 10.7 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFO96091.1 - 5.5e-09 36.0 4.6 0.00021 21.3 0.4 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO96091.1 - 1.1e-07 31.8 1.2 0.0056 16.7 1.1 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFO96091.1 - 2.8e-07 29.8 4.7 0.21 11.4 0.0 5.9 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFO96091.1 - 4.4e-07 29.9 4.2 4.1 8.0 0.1 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF4248 PF14053.1 KFO96091.1 - 0.00076 19.0 0.3 0.0022 17.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4248) SHNi-TPR PF10516.4 KFO96091.1 - 0.003 16.7 4.7 3.5 6.9 0.1 3.6 3 0 0 3 3 3 1 SHNi-TPR TPR_10 PF13374.1 KFO96091.1 - 0.01 15.7 8.6 2.1 8.3 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 KFO96091.1 - 0.01 15.6 0.0 5 7.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 KFO96091.1 - 0.91 9.8 5.9 3.9 7.7 0.1 2.9 3 0 0 3 3 2 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 KFO96091.1 - 1.2 9.1 3.6 40 4.1 0.1 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 KFO96092.1 - 1.6e-16 59.7 5.2 1e-12 47.4 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KFO96092.1 - 1.2e-13 49.9 0.3 0.0006 19.3 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFO96092.1 - 3e-12 45.4 5.1 0.00048 19.8 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96092.1 - 3e-08 33.5 0.1 0.04 14.5 0.0 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFO96092.1 - 1.4e-07 30.8 2.2 0.18 11.6 0.0 4.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO96092.1 - 6e-06 26.1 1.7 0.024 14.5 0.0 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFO96092.1 - 1.8e-05 24.5 0.0 5.8e-05 22.8 0.0 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFO96092.1 - 2.2e-05 24.3 1.2 0.00033 20.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO96092.1 - 3.9e-05 24.2 2.8 7.4e-05 23.3 0.0 2.8 3 1 1 4 4 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO96092.1 - 0.0003 21.0 2.8 0.0085 16.4 0.0 3.0 2 1 1 3 3 2 1 Tetratricopeptide repeat S1 PF00575.18 KFO96092.1 - 0.0062 16.6 0.0 0.038 14.0 0.0 2.2 1 1 0 1 1 1 1 S1 RNA binding domain TPR_7 PF13176.1 KFO96092.1 - 0.16 11.8 2.1 49 4.0 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat CENP-F_leu_zip PF10473.4 KFO96093.1 - 0.0011 18.8 19.7 0.0011 18.8 13.7 9.4 1 1 9 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFO96093.1 - 1.8 7.6 22.8 0.7 9.0 1.8 5.0 4 1 1 5 5 5 0 Reovirus sigma C capsid protein MMPL PF03176.10 KFO96093.1 - 3.2 6.3 6.6 3.5 6.2 0.8 2.7 2 1 0 2 2 2 0 MMPL family FXR1P_C PF12235.3 KFO96094.1 - 1.3e-64 217.0 19.0 1.3e-64 217.0 13.2 2.4 2 0 0 2 2 2 1 Fragile X-related 1 protein C terminal KH_1 PF00013.24 KFO96094.1 - 1.7e-18 66.0 1.7 5.2e-09 35.6 0.7 2.8 2 0 0 2 2 2 2 KH domain Agenet PF05641.7 KFO96094.1 - 6.4e-11 42.2 2.1 7.6e-11 42.0 0.1 2.1 2 0 0 2 2 2 1 Agenet domain KH_3 PF13014.1 KFO96094.1 - 3.1e-06 26.6 4.9 6.4e-06 25.7 0.3 3.3 4 0 0 4 4 4 1 KH domain KH_2 PF07650.12 KFO96094.1 - 0.00028 20.3 0.8 0.1 12.1 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 KFO96094.1 - 0.13 11.9 4.8 0.65 9.6 0.2 3.3 3 1 0 3 3 3 0 KH domain Peptidase_C65 PF10275.4 KFO96095.1 - 0.014 14.7 1.5 3.4 6.9 0.1 2.7 2 2 0 2 2 2 0 Peptidase C65 Otubain ANKH PF07260.6 KFO96096.1 - 2e-199 661.7 5.2 2e-199 661.7 3.6 1.6 2 0 0 2 2 2 1 Progressive ankylosis protein (ANKH) TMCO5 PF14992.1 KFO96096.1 - 0.066 12.3 0.4 0.12 11.4 0.3 1.3 1 0 0 1 1 1 0 TMCO5 family UCR_Fe-S_N PF10399.4 KFO96096.1 - 1 8.5 0.0 1 8.5 0.0 2.8 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SUI1 PF01253.17 KFO96097.1 - 3.2e-15 55.6 0.6 3.6e-15 55.5 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 LRR_6 PF13516.1 KFO96098.1 - 2.5e-26 88.7 0.7 0.022 14.7 0.0 10.6 11 0 0 11 11 11 6 Leucine Rich repeat F-box-like PF12937.2 KFO96098.1 - 4.2e-17 61.5 4.7 1.1e-16 60.1 3.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KFO96098.1 - 4.7e-16 57.9 0.0 0.0055 16.3 0.0 6.8 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96098.1 - 5.8e-16 56.0 7.0 0.49 10.6 0.0 10.8 10 1 0 10 10 10 3 Leucine Rich Repeat F-box PF00646.28 KFO96098.1 - 2.4e-12 46.1 2.3 2.4e-12 46.1 1.6 2.8 3 0 0 3 3 3 1 F-box domain LRR_7 PF13504.1 KFO96098.1 - 1.1e-11 42.8 10.1 1.9 9.0 0.0 9.9 10 1 0 10 10 10 2 Leucine rich repeat LRR_8 PF13855.1 KFO96098.1 - 3.5e-08 33.0 1.1 0.37 10.5 0.0 5.9 3 2 3 6 6 6 3 Leucine rich repeat RINGv PF12906.2 KFO96099.1 - 3.8e-13 49.2 8.1 9.9e-13 47.9 5.6 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 KFO96099.1 - 0.045 13.4 2.3 0.4 10.3 1.6 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABC_cobalt PF09819.4 KFO96099.1 - 0.13 12.2 2.8 0.2 11.6 1.9 1.2 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component zf-RING_2 PF13639.1 KFO96099.1 - 0.14 11.9 9.4 0.32 10.8 6.5 1.6 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 KFO96099.1 - 4.2 7.1 9.0 8.9 6.0 6.3 1.6 1 0 0 1 1 1 0 PHD-finger zf-C2H2_jaz PF12171.3 KFO96100.1 - 9.4e-13 47.9 8.3 5.4e-09 35.9 1.8 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFO96100.1 - 9.2e-06 25.7 9.5 8.3e-05 22.6 0.7 3.2 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFO96100.1 - 4.5e-05 23.4 3.3 4.5e-05 23.4 2.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 KFO96100.1 - 0.002 17.7 4.5 0.0027 17.3 0.3 2.4 2 0 0 2 2 2 1 DBF zinc finger zf-C2H2_4 PF13894.1 KFO96100.1 - 0.0061 16.8 1.3 0.0061 16.8 0.9 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger DUF629 PF04780.7 KFO96100.1 - 0.0079 14.7 0.9 0.013 14.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 KFO96100.1 - 0.015 15.1 1.3 0.015 15.1 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger AKAP95 PF04988.7 KFO96100.1 - 0.11 12.2 7.4 2.8 7.7 0.1 2.7 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 KFO96100.1 - 4.5 7.8 10.0 0.14 12.5 1.4 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LYAR PF08790.6 KFO96100.1 - 9.1 6.0 7.4 5.9 6.6 0.1 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Reticulon PF02453.12 KFO96101.1 - 0.035 13.7 1.8 0.069 12.7 1.2 1.5 1 0 0 1 1 1 0 Reticulon ALMT PF11744.3 KFO96101.1 - 0.06 11.9 0.4 0.21 10.2 0.0 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter BASP1 PF05466.7 KFO96103.1 - 9.6e-94 313.6 94.1 1.1e-93 313.4 65.2 1.0 1 0 0 1 1 1 1 Brain acid soluble protein 1 (BASP1 protein) Utp14 PF04615.8 KFO96103.1 - 7 4.6 50.8 7.5 4.5 35.2 1.0 1 0 0 1 1 1 0 Utp14 protein PNPase_C PF12111.3 KFO96104.1 - 0.21 10.8 0.5 0.53 9.5 0.4 1.6 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Yae1_N PF09811.4 KFO96105.1 - 1.8e-12 46.5 34.0 8.1e-05 22.0 4.5 3.2 2 1 0 2 2 2 2 Essential protein Yae1, N terminal Cadherin PF00028.12 KFO96106.1 - 2.3e-83 274.5 7.8 1.2e-18 67.1 0.2 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFO96106.1 - 9.2e-54 181.5 1.1 2.4e-53 180.1 0.8 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region ASFV_J13L PF05568.6 KFO96106.1 - 0.063 12.8 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Big_3_4 PF13754.1 KFO96106.1 - 0.19 12.0 7.3 3.3 8.0 0.2 3.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) CTD PF12815.2 KFO96108.1 - 6.4 7.2 28.6 1.5e+04 -11.3 19.8 3.8 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 fn3 PF00041.16 KFO96109.1 - 0.0046 17.0 0.2 0.0094 16.0 0.1 1.4 1 1 0 1 1 1 1 Fibronectin type III domain fn3 PF00041.16 KFO96110.1 - 2.4e-186 604.4 59.2 1.2e-12 47.7 0.1 20.5 20 0 0 20 20 20 19 Fibronectin type III domain Y_phosphatase PF00102.22 KFO96110.1 - 1.3e-76 257.0 0.0 2.8e-76 255.9 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Interfer-bind PF09294.5 KFO96110.1 - 3.4e-12 46.3 2.7 4.4 7.3 0.0 12.1 13 0 0 13 13 13 2 Interferon-alpha/beta receptor, fibronectin type III Y_phosphatase3 PF13350.1 KFO96110.1 - 0.00072 19.8 0.2 0.0027 17.9 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFO96110.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.15 KFO96110.1 - 0.046 13.2 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2369 PF10179.4 KFO96110.1 - 0.095 11.7 1.9 7.4 5.5 0.0 4.0 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) PDZ PF00595.19 KFO96111.1 - 3.9e-21 75.0 0.4 6.5e-21 74.2 0.3 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 KFO96111.1 - 1.7e-17 62.8 0.1 3.2e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 L27 domain PDZ_2 PF13180.1 KFO96111.1 - 6.3e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Prefoldin_2 PF01920.15 KFO96111.1 - 0.43 10.3 7.4 5.5 6.7 2.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit ECH PF00378.15 KFO96111.1 - 0.68 9.0 4.1 3.1 6.8 0.8 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family AMP-binding PF00501.23 KFO96112.1 - 8.6e-75 251.6 0.0 1.1e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO96112.1 - 1.1e-14 55.1 0.4 3.5e-14 53.5 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain rRNA_processing PF08524.6 KFO96115.1 - 0.0036 17.0 37.4 0.011 15.5 25.9 1.7 1 1 0 1 1 1 1 rRNA processing RR_TM4-6 PF06459.7 KFO96115.1 - 0.38 10.6 12.9 0.43 10.4 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4544 PF15077.1 KFO96115.1 - 6.3 6.2 10.9 20 4.6 7.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4544) DUF1910 PF08928.5 KFO96115.1 - 7.7 6.5 10.0 1.2 9.1 4.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Hid1 PF12722.2 KFO96115.1 - 9.3 3.7 14.0 10 3.6 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_32 PF13679.1 KFO96116.1 - 2.8e-28 98.3 6.3 5.7e-27 94.1 4.3 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO96116.1 - 5.2e-05 22.8 0.0 0.00016 21.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO96116.1 - 0.00064 19.4 0.0 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO96116.1 - 0.00091 19.7 0.0 0.0025 18.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO96116.1 - 0.032 14.6 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFO96116.1 - 0.048 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KFO96116.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.7 KFO96116.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF1736 PF08409.6 KFO96117.1 - 2.3e-32 110.3 2.6 1.6e-31 107.6 1.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) TPR_1 PF00515.23 KFO96117.1 - 3.7e-25 86.4 5.9 3.6e-05 23.1 0.1 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFO96117.1 - 8.3e-22 76.9 8.9 1.1e-10 41.3 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFO96117.1 - 1.1e-21 76.1 9.0 6.7e-10 38.4 2.0 3.4 1 1 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 KFO96117.1 - 2.5e-20 70.7 6.3 0.00018 21.1 0.2 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFO96117.1 - 5.5e-14 50.8 9.3 0.0052 16.4 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFO96117.1 - 1.8e-11 43.5 6.2 0.011 15.6 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFO96117.1 - 4.6e-11 41.6 4.8 0.013 15.2 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFO96117.1 - 6.9e-11 41.4 6.7 0.41 10.9 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFO96117.1 - 1.4e-10 41.5 0.6 0.0043 17.6 0.1 4.1 2 2 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KFO96117.1 - 3.4e-07 30.3 6.4 0.0024 17.9 1.0 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFO96117.1 - 4.4e-07 29.9 5.0 0.0096 16.3 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO96117.1 - 5.5e-06 26.6 0.5 0.023 15.0 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96117.1 - 5.7e-06 26.5 0.1 0.27 11.9 0.0 5.0 3 3 3 6 6 6 1 Tetratricopeptide repeat PMT_2 PF13231.1 KFO96117.1 - 1.4e-05 25.0 6.1 1.4e-05 25.0 4.2 2.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 KFO96117.1 - 0.0023 17.3 10.1 0.0023 17.3 7.0 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Keratin_assoc PF09775.4 KFO96117.1 - 0.0046 16.5 0.1 0.015 14.8 0.1 1.8 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 TPR_3 PF07720.7 KFO96117.1 - 0.0049 16.6 7.0 0.62 9.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.4 KFO96117.1 - 0.045 13.1 0.7 2 7.7 0.1 2.9 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DUF2225 PF09986.4 KFO96117.1 - 0.16 11.3 1.6 0.54 9.6 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 KFO96117.1 - 0.17 11.8 0.0 19 5.2 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFO96117.1 - 0.2 12.1 0.2 1.2 9.7 0.0 2.4 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_15 PF13429.1 KFO96117.1 - 0.28 10.1 3.0 5.1 6.0 0.1 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KFO96117.1 - 0.52 10.2 4.3 6.7 6.6 0.1 2.9 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain zf-CCCH PF00642.19 KFO96118.1 - 1.3e-13 50.2 16.4 3.9e-05 23.2 0.6 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Baculo_PP31 PF05311.6 KFO96118.1 - 1.8 7.7 11.7 3.9 6.6 8.1 1.5 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) OB_NTP_bind PF07717.11 KFO96120.1 - 1.3e-15 57.1 0.0 3.3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFO96120.1 - 7e-12 45.0 0.0 8.3e-11 41.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 KFO96120.1 - 8.8e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 KFO96120.1 - 0.002 17.6 0.0 0.09 12.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KFO96120.1 - 0.0034 16.8 0.1 0.049 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFO96120.1 - 0.017 15.2 0.1 0.1 12.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 KFO96120.1 - 0.092 11.6 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 KFO96120.1 - 0.26 10.3 0.0 0.66 9.0 0.0 1.6 2 0 0 2 2 2 0 KaiC V-set PF07686.12 KFO96121.1 - 2.2e-17 62.9 1.4 3.6e-13 49.4 0.0 3.4 1 1 2 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.11 KFO96121.1 - 1.9e-13 50.0 0.5 1.1e-06 28.4 0.0 3.1 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96121.1 - 4.3e-11 42.7 1.0 3.8e-06 26.9 0.1 2.5 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFO96121.1 - 6.3e-06 26.5 0.1 0.21 12.1 0.0 3.6 2 2 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFO96121.1 - 0.00025 21.1 0.2 0.045 13.8 0.0 3.9 3 2 0 3 3 3 1 Immunoglobulin domain Herpes_gE PF02480.11 KFO96121.1 - 0.0024 16.2 0.1 2.1 6.5 0.1 2.5 1 1 2 3 3 3 2 Alphaherpesvirus glycoprotein E SMN PF06003.7 KFO96121.1 - 0.015 14.4 1.4 0.024 13.7 0.9 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) FAM176 PF14851.1 KFO96121.1 - 0.015 15.0 0.1 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 FAM176 family TMEM51 PF15345.1 KFO96121.1 - 0.021 14.5 1.4 0.036 13.7 1.0 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 DUF1191 PF06697.7 KFO96121.1 - 0.03 13.1 0.1 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Glycophorin_A PF01102.13 KFO96121.1 - 0.078 12.7 2.6 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Glycophorin A SR-25 PF10500.4 KFO96121.1 - 1.1 8.7 12.8 1.7 8.0 8.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HSP70 PF00012.15 KFO96122.1 - 1e-277 921.9 12.4 1.2e-277 921.8 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFO96122.1 - 1.1e-18 66.8 0.5 3.2e-17 62.1 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFO96122.1 - 0.00034 20.4 2.9 0.12 12.2 0.1 3.5 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KFO96122.1 - 0.0014 18.3 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KFO96122.1 - 0.0063 15.3 0.4 0.046 12.5 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 KFO96122.1 - 0.012 14.8 0.1 4.4 6.5 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 KFO96122.1 - 0.026 13.4 0.9 0.12 11.3 0.0 2.3 3 0 0 3 3 3 0 StbA protein Hydantoinase_A PF01968.13 KFO96122.1 - 0.048 12.7 1.6 0.45 9.5 0.1 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Homeobox PF00046.24 KFO96123.1 - 1.8e-22 78.6 1.9 2.7e-22 78.1 1.3 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFO96123.1 - 0.014 14.4 0.1 0.033 13.2 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFO96123.1 - 0.3 10.8 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 0 Homeobox KN domain C2-set_2 PF08205.7 KFO96124.1 - 4.4e-09 36.1 0.2 8.1e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFO96124.1 - 4.9e-08 32.7 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain C1-set PF07654.10 KFO96124.1 - 5.8e-05 23.0 1.4 0.00019 21.3 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin C1-set domain DUF3357 PF11837.3 KFO96124.1 - 0.0014 18.4 0.1 0.0023 17.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) ig PF00047.20 KFO96124.1 - 0.002 18.1 1.8 1.1 9.3 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.1 KFO96124.1 - 0.0024 17.9 2.5 0.32 11.1 0.4 2.6 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFO96124.1 - 0.0038 17.1 0.8 0.056 13.3 0.0 2.7 2 1 1 3 3 3 1 Immunoglobulin V-set domain Sarcoglycan_2 PF05510.8 KFO96124.1 - 0.011 14.1 0.0 0.021 13.1 0.0 1.5 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Herpes_gE PF02480.11 KFO96124.1 - 0.012 13.8 0.0 0.41 8.8 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Lep_receptor_Ig PF06328.6 KFO96124.1 - 0.045 13.6 0.1 2.4 8.0 0.0 2.4 1 1 1 2 2 2 0 Ig-like C2-type domain Ig_3 PF13927.1 KFO96124.1 - 0.17 12.4 2.3 3.2 8.3 0.3 2.4 2 0 0 2 2 2 0 Immunoglobulin domain His_Phos_1 PF00300.17 KFO96125.1 - 9.9e-24 84.2 0.0 2.8e-23 82.7 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.1 KFO96125.1 - 4.6e-17 61.3 0.1 1.4e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain 2_5_RNA_ligase2 PF13563.1 KFO96125.1 - 8.7e-07 28.7 0.7 2.2e-06 27.4 0.2 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily SH3_1 PF00018.23 KFO96125.1 - 4e-05 22.9 0.0 8.2e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LigT_PEase PF02834.11 KFO96125.1 - 4.7e-05 23.2 0.1 0.3 11.0 0.1 2.7 2 0 0 2 2 2 2 LigT like Phosphoesterase His_Phos_2 PF00328.17 KFO96125.1 - 0.044 13.1 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Ldl_recept_a PF00057.13 KFO96126.1 - 1.2e-107 351.4 210.8 4.2e-14 52.1 5.5 12.1 11 1 1 12 12 12 11 Low-density lipoprotein receptor domain class A fn3 PF00041.16 KFO96126.1 - 2.8e-33 113.8 12.7 1.4e-08 34.6 0.0 6.4 6 0 0 6 6 6 5 Fibronectin type III domain Ldl_recept_b PF00058.12 KFO96126.1 - 1.3e-24 86.2 6.5 2.8e-08 33.9 0.1 5.7 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B BNR PF02012.15 KFO96126.1 - 0.00026 20.3 13.3 2.2 8.4 0.2 5.6 5 0 0 5 5 5 2 BNR/Asp-box repeat DUF3377 PF11857.3 KFO96126.1 - 0.036 13.6 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) FA_hydroxylase PF04116.8 KFO96127.1 - 1e-13 51.6 25.4 6.4e-13 49.1 15.6 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily LRR_4 PF12799.2 KFO96128.1 - 1.3e-11 43.8 24.1 1.7e-05 24.3 1.4 5.0 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO96128.1 - 4.8e-10 39.0 18.3 0.0007 19.2 1.4 4.2 2 1 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.1 KFO96128.1 - 2.7e-07 30.3 2.5 5.7e-05 22.7 0.1 3.1 1 1 2 3 3 3 1 Leucine-rich repeat Ubiquitin_2 PF14560.1 KFO96128.1 - 1.9e-06 27.9 0.1 8.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain LRR_6 PF13516.1 KFO96128.1 - 0.00025 20.8 15.3 3 8.1 0.1 6.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 KFO96128.1 - 0.0033 17.2 17.8 1.7 8.9 0.2 6.2 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 KFO96128.1 - 0.024 14.7 17.7 4.2 7.9 0.2 6.8 7 0 0 7 7 7 0 Leucine rich repeat APG12 PF04110.8 KFO96128.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 ANF_receptor PF01094.23 KFO96129.1 - 1.2e-58 198.6 0.0 1.7e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 KFO96129.1 - 6.1e-47 159.0 0.1 1e-46 158.3 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 KFO96129.1 - 1.3e-26 92.2 0.1 3.1e-26 91.1 0.1 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFO96129.1 - 1.6e-22 79.8 0.0 3.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFO96129.1 - 0.0032 16.8 0.0 0.0084 15.4 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein TRAM_LAG1_CLN8 PF03798.11 KFO96130.1 - 8.2e-05 22.2 0.1 8.2e-05 22.2 0.1 1.4 2 0 0 2 2 2 1 TLC domain DUF998 PF06197.8 KFO96130.1 - 0.021 14.1 0.3 0.029 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Acyl_transf_3 PF01757.17 KFO96130.1 - 0.05 12.4 3.1 0.12 11.2 2.1 1.6 1 1 0 1 1 1 0 Acyltransferase family TRAM_LAG1_CLN8 PF03798.11 KFO96131.1 - 0.00019 21.0 0.1 0.00019 21.0 0.1 2.0 2 1 0 2 2 2 1 TLC domain DUF998 PF06197.8 KFO96131.1 - 0.02 14.2 0.6 0.026 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Pou PF00157.12 KFO96132.1 - 2.9e-39 132.5 0.1 5.8e-39 131.6 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFO96132.1 - 1.5e-18 66.1 3.3 3.8e-18 64.8 2.3 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO96132.1 - 0.0062 16.2 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.17 KFO96132.1 - 0.12 12.2 0.2 1.1 9.1 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix OAF PF14941.1 KFO96133.1 - 3.5e-111 370.1 3.4 3.9e-111 369.9 2.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator, Out at first BRICHOS PF04089.9 KFO96133.1 - 0.046 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 BRICHOS domain C2-set_2 PF08205.7 KFO96134.1 - 2.9e-19 68.7 0.5 6.2e-18 64.4 0.0 2.5 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFO96134.1 - 3.3e-17 62.3 1.8 4.6e-07 29.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFO96134.1 - 4.4e-17 61.9 1.3 2.7e-08 33.8 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFO96134.1 - 2.7e-13 50.2 6.3 6.7e-05 23.3 0.1 3.9 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFO96134.1 - 2.8e-12 46.5 1.6 1.1e-11 44.6 0.0 2.5 3 1 0 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.11 KFO96134.1 - 4e-08 32.9 0.3 0.00068 19.4 0.0 3.5 3 1 0 3 3 3 2 Immunoglobulin I-set domain Herpes_gE PF02480.11 KFO96134.1 - 0.061 11.5 0.0 0.08 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KFO96135.1 - 0.003 17.9 0.0 0.004 17.5 0.0 1.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 KFO96135.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Protocadherin IncA PF04156.9 KFO96135.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein Syndecan PF01034.15 KFO96135.1 - 0.14 11.8 0.7 0.22 11.1 0.5 1.3 1 0 0 1 1 1 0 Syndecan domain V-set PF07686.12 KFO96136.1 - 1.1e-05 25.3 0.8 1.8e-05 24.6 0.6 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFO96136.1 - 0.00096 19.2 1.0 0.0021 18.1 0.3 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFO96136.1 - 0.0042 17.1 0.8 0.0056 16.7 0.6 1.2 1 0 0 1 1 1 1 Immunoglobulin domain NEAT PF05031.7 KFO96136.1 - 0.0044 17.0 0.1 0.0099 15.8 0.0 1.6 2 0 0 2 2 2 1 Iron Transport-associated domain I-set PF07679.11 KFO96136.1 - 0.015 15.0 0.3 0.029 14.2 0.2 1.6 1 1 0 1 1 1 0 Immunoglobulin I-set domain RPA_C PF08784.6 KFO96136.1 - 0.031 14.7 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal Herpes_gE PF02480.11 KFO96136.1 - 0.073 11.3 0.8 0.088 11.0 0.5 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Alpha_adaptinC2 PF02883.15 KFO96136.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Adaptin C-terminal domain CUB PF00431.15 KFO96137.1 - 2.9e-24 85.2 0.0 4.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain Fz PF01392.17 KFO96137.1 - 3.2e-20 72.5 2.2 3.2e-20 72.5 1.5 1.9 2 0 0 2 2 2 1 Fz domain Ldl_recept_a PF00057.13 KFO96137.1 - 2.3e-09 36.9 9.4 2.3e-09 36.9 6.5 2.3 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A C1q PF00386.16 KFO96138.1 - 1.8e-36 124.9 0.0 2.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFO96138.1 - 2.4e-10 39.7 34.1 4.2e-08 32.6 23.6 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.13 KFO96138.1 - 0.047 13.2 0.1 0.3 10.6 0.1 1.9 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family zf-C3HC4_3 PF13920.1 KFO96139.1 - 6.6e-14 51.3 11.2 1e-13 50.7 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO96139.1 - 1.4e-06 28.0 12.6 2.3e-06 27.3 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFO96139.1 - 2.2e-06 27.6 12.2 3.5e-06 26.9 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO96139.1 - 0.012 15.3 11.6 0.023 14.3 8.1 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 KFO96139.1 - 1.6 8.5 8.5 0.53 10.1 3.7 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KFO96139.1 - 5 6.7 8.7 18 4.9 6.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 C2-set_2 PF08205.7 KFO96140.1 - 1.1e-27 95.7 2.7 1.9e-22 78.9 0.5 3.6 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFO96140.1 - 6.2e-23 80.7 0.2 4.1e-09 36.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFO96140.1 - 5.2e-18 64.6 0.1 1.6e-05 24.6 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFO96140.1 - 1.3e-17 64.0 4.2 6.6e-05 23.3 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFO96140.1 - 4.6e-12 45.8 1.7 3.1e-05 24.0 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain C1-set PF07654.10 KFO96140.1 - 1.1e-06 28.5 2.6 0.0012 18.7 0.3 3.4 3 0 0 3 3 3 2 Immunoglobulin C1-set domain V-set PF07686.12 KFO96140.1 - 1.6e-05 24.7 2.4 0.63 9.9 0.0 4.2 3 2 0 3 3 3 2 Immunoglobulin V-set domain Homeobox PF00046.24 KFO96141.1 - 3.2e-25 87.4 6.0 7.1e-25 86.3 4.2 1.6 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFO96141.1 - 2.4e-10 39.5 1.8 4.1e-10 38.8 1.3 1.4 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFO96141.1 - 0.004 16.8 0.1 0.0088 15.7 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Aminotran_1_2 PF00155.16 KFO96142.1 - 2.5e-59 201.0 0.0 3.4e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFO96142.1 - 0.00087 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SbcD_C PF12320.3 KFO96142.1 - 0.0065 16.4 0.1 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 Type 5 capsule protein repressor C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 KFO96144.1 - 6.2e-20 71.8 0.0 1e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 KFO96145.1 - 1.4e-06 28.2 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RFXA_RFXANK_bdg PF15289.1 KFO96145.1 - 0.091 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain API5 PF05918.6 KFO96146.1 - 9.1e-118 394.1 19.3 2.4e-116 389.4 13.3 2.3 1 1 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 KFO96146.1 - 3.2e-05 24.1 0.3 0.00025 21.2 0.2 2.3 1 1 0 2 2 2 1 HEAT repeats MMS19_N PF14500.1 KFO96146.1 - 0.011 14.9 3.0 0.064 12.5 2.1 2.1 1 1 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF2435 PF10363.4 KFO96146.1 - 0.012 15.5 0.2 2.4 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Dak2 PF02734.12 KFO96146.1 - 0.044 13.4 0.0 0.094 12.3 0.0 1.6 1 1 0 1 1 1 0 DAK2 domain InvH PF04741.7 KFO96146.1 - 0.057 13.2 0.1 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 InvH outer membrane lipoprotein LRR_8 PF13855.1 KFO96147.1 - 1.2e-39 133.8 22.1 3.2e-12 46.0 0.2 5.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFO96147.1 - 3.3e-22 77.6 27.7 6.3e-08 32.0 0.8 5.8 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFO96147.1 - 2.3e-20 72.5 0.0 1.6e-12 47.2 0.0 2.7 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFO96147.1 - 2.2e-15 54.3 28.8 0.023 14.6 0.0 9.8 10 0 0 10 10 10 5 Leucine Rich Repeat I-set PF07679.11 KFO96147.1 - 8.4e-14 51.1 0.0 1.6e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96147.1 - 2.8e-08 33.7 0.2 7.7e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO96147.1 - 8.8e-08 32.0 0.1 2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_7 PF13504.1 KFO96147.1 - 3.7e-06 26.2 25.6 1.5 9.3 0.0 8.7 9 0 0 9 9 8 4 Leucine rich repeat ig PF00047.20 KFO96147.1 - 4.9e-06 26.5 2.1 5.6e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFO96147.1 - 0.00019 21.8 4.8 0.00022 21.6 0.2 3.3 2 2 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.11 KFO96147.1 - 0.0031 15.8 3.8 0.026 12.8 0.4 2.3 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E gpUL132 PF11359.3 KFO96147.1 - 0.0047 16.2 1.8 0.0053 16.1 0.4 1.6 1 1 0 1 1 1 1 Glycoprotein UL132 LRR_9 PF14580.1 KFO96147.1 - 0.03 13.8 4.4 2 7.9 0.2 2.9 1 1 2 3 3 3 0 Leucine-rich repeat Syndecan PF01034.15 KFO96147.1 - 0.17 11.5 0.3 0.33 10.6 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain LRR_6 PF13516.1 KFO96147.1 - 3.5 7.9 24.9 11 6.4 0.2 7.3 6 2 1 7 7 7 0 Leucine Rich repeat LRRNT PF01462.13 KFO96147.1 - 7.8 6.1 12.7 0.031 13.7 1.8 2.4 3 0 0 3 3 2 0 Leucine rich repeat N-terminal domain RVT_1 PF00078.22 KFO96148.1 - 0.018 14.3 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RAG2 PF03089.9 KFO96149.1 - 4.1e-170 564.9 0.1 5.1e-170 564.6 0.1 1.1 1 0 0 1 1 1 1 Recombination activating protein 2 RAG2_PHD PF13341.1 KFO96149.1 - 1e-42 143.9 1.2 2.2e-42 142.8 0.9 1.6 1 0 0 1 1 1 1 RAG2 PHD domain Kelch_3 PF13415.1 KFO96149.1 - 3e-09 36.8 0.8 2.5e-05 24.3 0.0 4.5 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO96149.1 - 1.7e-07 31.0 0.5 0.24 11.4 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 KFO96149.1 - 3.7e-05 23.3 0.6 3.7 7.3 0.1 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain PHD PF00628.24 KFO96149.1 - 0.0032 17.1 2.0 0.0051 16.4 0.1 2.3 3 0 0 3 3 3 1 PHD-finger Kelch_6 PF13964.1 KFO96149.1 - 0.04 14.0 3.8 3.8 7.8 0.0 4.6 5 0 0 5 5 5 0 Kelch motif AF1Q PF15017.1 KFO96149.1 - 0.82 9.6 5.4 1.9 8.4 3.7 1.6 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator RAG1 PF12940.2 KFO96150.1 - 8.9e-232 769.1 0.1 1.5e-231 768.3 0.0 1.4 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) zf-RAG1 PF10426.4 KFO96150.1 - 3.2e-16 58.9 2.7 3.2e-16 58.9 1.8 3.4 3 0 0 3 3 3 1 Recombination-activating protein 1 zinc-finger domain zf-C3HC4 PF00097.20 KFO96150.1 - 5.2e-07 29.2 14.6 5.2e-07 29.2 10.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO96150.1 - 8.6e-06 25.6 15.0 8.6e-06 25.6 10.4 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFO96150.1 - 3e-05 23.7 13.0 9.1e-05 22.1 6.0 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFO96150.1 - 0.0038 17.0 13.6 0.0038 17.0 9.5 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFO96150.1 - 0.13 11.9 11.8 0.084 12.6 6.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 KFO96150.1 - 0.69 9.7 22.8 0.014 15.1 9.5 3.1 3 0 0 3 3 3 0 Ring finger domain zf-TRAF PF02176.13 KFO96151.1 - 4.2e-29 100.6 27.8 2.7e-18 66.0 2.4 3.9 2 1 1 3 3 3 3 TRAF-type zinc finger MATH PF00917.21 KFO96151.1 - 9e-24 84.0 0.0 2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 MATH domain zf-C3HC4_2 PF13923.1 KFO96151.1 - 2.4e-10 40.2 5.7 2.4e-10 40.2 4.0 3.9 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO96151.1 - 8.4e-09 34.9 5.2 8.4e-09 34.9 3.6 4.1 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO96151.1 - 1e-08 34.8 4.6 1e-08 34.8 3.2 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO96151.1 - 2e-06 27.3 4.9 2e-06 27.3 3.4 3.9 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFO96151.1 - 2.1e-06 27.5 4.5 2.1e-06 27.5 3.1 3.8 2 1 2 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFO96151.1 - 1.6e-05 24.5 4.3 1.6e-05 24.5 3.0 4.2 2 1 2 4 4 2 1 zinc-RING finger domain SlyX PF04102.7 KFO96151.1 - 0.00013 22.2 3.7 0.00013 22.2 2.6 2.2 2 0 0 2 2 2 1 SlyX Sina PF03145.11 KFO96151.1 - 0.0008 19.1 20.8 0.0069 16.0 4.4 3.3 1 1 2 3 3 3 2 Seven in absentia protein family Med21 PF11221.3 KFO96151.1 - 0.0029 17.5 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Subunit 21 of Mediator complex PspA_IM30 PF04012.7 KFO96151.1 - 0.0047 16.3 1.4 0.012 14.9 1.0 1.7 1 0 0 1 1 1 1 PspA/IM30 family Spc7 PF08317.6 KFO96151.1 - 0.0081 14.8 0.2 0.013 14.1 0.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 KFO96151.1 - 0.0088 15.8 1.8 0.016 15.0 1.3 1.3 1 0 0 1 1 1 1 Tropomyosin like U-box PF04564.10 KFO96151.1 - 0.0099 15.8 0.1 0.056 13.4 0.0 2.3 3 0 0 3 3 1 1 U-box domain zf-RING_UBOX PF13445.1 KFO96151.1 - 0.01 15.5 6.3 0.01 15.5 4.4 2.7 2 0 0 2 2 1 1 RING-type zinc-finger ATG16 PF08614.6 KFO96151.1 - 0.017 14.9 0.6 0.028 14.2 0.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Synaphin PF05835.7 KFO96151.1 - 0.018 15.1 0.8 0.038 14.1 0.6 1.5 1 0 0 1 1 1 0 Synaphin protein CENP-F_leu_zip PF10473.4 KFO96151.1 - 0.02 14.7 0.9 0.055 13.3 0.6 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 KFO96151.1 - 0.021 12.5 2.1 0.032 11.9 1.5 1.2 1 0 0 1 1 1 0 Myosin tail DUF4455 PF14643.1 KFO96151.1 - 0.021 13.4 0.8 0.033 12.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) CENP-Q PF13094.1 KFO96151.1 - 0.042 13.8 0.4 0.09 12.8 0.3 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 KFO96151.1 - 0.045 13.5 3.3 0.085 12.6 2.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.15 KFO96151.1 - 0.074 12.1 1.7 0.12 11.4 1.2 1.2 1 0 0 1 1 1 0 Tropomyosin DUF465 PF04325.8 KFO96151.1 - 0.085 12.5 1.5 11 5.7 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF465) ADIP PF11559.3 KFO96151.1 - 0.13 12.1 3.0 0.28 11.0 2.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DM PF00751.13 KFO96151.1 - 0.35 10.4 17.8 0.71 9.4 1.4 3.9 1 1 2 3 3 3 0 DM DNA binding domain HbrB PF08539.6 KFO96152.1 - 1.5e-28 99.6 1.2 8.5e-27 93.9 0.8 2.3 1 1 0 1 1 1 1 HbrB-like HCaRG PF07258.9 KFO96153.1 - 1.7e-30 105.9 0.0 1.8e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein Ldl_recept_a PF00057.13 KFO96154.1 - 6.7e-32 109.1 45.3 1.9e-11 43.6 6.9 3.4 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A PspB PF06667.7 KFO96154.1 - 0.21 11.5 0.6 0.39 10.6 0.4 1.4 1 0 0 1 1 1 0 Phage shock protein B Trypsin PF00089.21 KFO96155.1 - 1.3e-36 126.3 0.1 1.9e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 KFO96155.1 - 1.9e-24 85.8 0.2 4.5e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 CUB domain Sushi PF00084.15 KFO96155.1 - 9.6e-16 57.8 9.0 1.5e-08 34.8 0.3 3.5 3 0 0 3 3 3 2 Sushi domain (SCR repeat) EGF PF00008.22 KFO96155.1 - 3.5e-08 33.2 6.5 3.5e-08 33.2 4.5 3.8 5 0 0 5 5 5 1 EGF-like domain EGF_2 PF07974.8 KFO96155.1 - 0.00046 20.2 9.0 0.00046 20.2 6.2 4.6 5 0 0 5 5 5 1 EGF-like domain hEGF PF12661.2 KFO96155.1 - 0.0064 16.4 1.6 0.0064 16.4 1.1 4.4 3 0 0 3 3 3 1 Human growth factor-like EGF CUB_2 PF02408.15 KFO96155.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 CUB-like domain Trypsin_2 PF13365.1 KFO96155.1 - 0.026 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Trypsin-like peptidase domain Dymeclin PF09742.4 KFO96155.1 - 0.13 10.3 0.1 0.18 9.8 0.1 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein SDF PF00375.13 KFO96156.1 - 3.6e-126 421.0 28.9 4.2e-126 420.8 20.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Xlink PF00193.12 KFO96157.1 - 6.5e-23 80.6 0.9 9.6e-23 80.0 0.1 1.7 2 0 0 2 2 2 1 Extracellular link domain TMEM51 PF15345.1 KFO96157.1 - 0.015 14.9 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 2-oxoacid_dh PF00198.18 KFO96158.1 - 2.9e-80 268.8 0.3 3.5e-80 268.5 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFO96158.1 - 4.5e-21 74.2 0.4 1.1e-20 73.0 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KFO96158.1 - 5.1e-12 45.2 0.0 1.6e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KFO96158.1 - 0.00035 20.1 0.0 0.031 13.9 0.0 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like QRPTase_N PF02749.11 KFO96158.1 - 0.077 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_2 PF12700.2 KFO96158.1 - 0.096 11.8 0.0 0.23 10.5 0.0 1.6 1 1 0 1 1 1 0 HlyD family secretion protein HlyD PF00529.15 KFO96158.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 HlyD family secretion protein Aldolase_II PF00596.16 KFO96159.1 - 2.6e-42 144.5 0.0 3e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ets PF00178.17 KFO96160.1 - 2.2e-31 107.7 4.3 1.3e-30 105.3 0.7 2.4 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFO96160.1 - 8.4e-25 86.3 3.9 9.1e-25 86.2 1.8 1.7 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain DUF3414 PF11894.3 KFO96160.1 - 0.14 9.0 0.1 0.19 8.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) PH PF00169.24 KFO96161.1 - 3e-05 24.1 2.2 4.6e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 PH domain ERM PF00769.14 KFO96161.1 - 0.0021 17.6 27.3 0.0021 17.6 18.9 2.3 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 KFO96161.1 - 0.011 14.8 6.2 0.22 10.6 0.3 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein KNOX2 PF03791.8 KFO96161.1 - 0.028 13.6 0.2 0.028 13.6 0.2 3.6 4 1 0 4 4 4 0 KNOX2 domain EIF_2_alpha PF07541.7 KFO96161.1 - 0.53 10.0 5.1 0.15 11.7 0.6 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit DUF3726 PF12525.3 KFO96161.1 - 8 6.3 10.7 2 8.2 0.2 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF3726) Zip PF02535.17 KFO96162.1 - 2.8e-37 128.4 22.6 1.6e-31 109.5 7.8 2.4 1 1 1 2 2 2 2 ZIP Zinc transporter Cyto_ox_2 PF02322.10 KFO96162.1 - 0.13 11.4 8.4 0.23 10.6 5.8 1.5 1 1 0 1 1 1 0 Cytochrome oxidase subunit II 7TM-7TMR_HD PF07698.6 KFO96162.1 - 1.4 8.2 9.6 0.087 12.2 2.6 2.1 3 1 0 3 3 3 0 7TM receptor with intracellular HD hydrolase ER PF01133.12 KFO96163.1 - 5.4e-52 173.8 0.4 6e-52 173.6 0.3 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary DUF3407 PF11887.3 KFO96163.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Glycos_transf_2 PF00535.21 KFO96164.1 - 3.2e-23 82.2 0.0 5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFO96164.1 - 5.4e-16 58.7 3.1 9.6e-16 57.9 2.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.4 KFO96164.1 - 1.9e-11 43.5 0.0 5.7e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KFO96164.1 - 1.5e-09 37.9 0.0 2.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFO96164.1 - 1.8e-08 33.7 0.1 3.4e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4227 PF14004.1 KFO96164.1 - 0.0082 15.9 0.3 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4227) DNA_pol_A_exo1 PF01612.15 KFO96165.1 - 6.4e-17 61.5 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease WD40 PF00400.27 KFO96166.1 - 3.2e-19 68.0 13.3 3.5e-05 23.5 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Spectrin PF00435.16 KFO96167.1 - 5.5e-77 254.8 26.0 5.2e-27 94.1 4.9 4.3 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.26 KFO96167.1 - 9.8e-40 134.9 0.1 2e-20 72.8 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KFO96167.1 - 4.4e-26 90.6 0.0 1.9e-25 88.5 0.0 2.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KFO96167.1 - 1.7e-12 46.8 0.0 7.3e-10 38.3 0.0 2.9 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_1 PF00036.27 KFO96167.1 - 2.4e-07 29.5 1.0 0.0053 15.9 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFO96167.1 - 5.3e-06 25.8 0.6 0.012 15.4 0.1 3.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFO96167.1 - 3.3e-05 23.4 1.8 0.00071 19.1 0.2 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 KFO96167.1 - 0.0001 22.3 0.2 0.00085 19.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair XisI PF08869.6 KFO96167.1 - 0.0084 16.2 0.9 0.034 14.2 0.6 2.0 1 0 0 1 1 1 1 XisI protein RRM_1 PF00076.17 KFO96168.1 - 2.2e-34 116.8 0.2 9.9e-17 60.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96168.1 - 4.6e-23 80.9 0.1 5.9e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96168.1 - 1.7e-15 56.5 0.1 2.2e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO96168.1 - 1.7e-08 34.2 0.4 4.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFO96168.1 - 0.04 13.6 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 KFO96168.1 - 0.044 13.2 0.1 0.2 11.1 0.1 2.2 1 0 0 1 1 1 0 Ribonuclease B OB domain DbpA PF03880.10 KFO96168.1 - 0.065 12.9 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain Cas_Cas2CT1978 PF09707.5 KFO96168.1 - 0.15 12.0 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) CDC45 PF02724.9 KFO96168.1 - 4 5.3 14.1 5.1 5.0 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Gag_spuma PF03276.9 KFO96168.1 - 6.3 5.0 12.5 10 4.3 8.7 1.3 1 0 0 1 1 1 0 Spumavirus gag protein Rad51 PF08423.6 KFO96171.1 - 1.2e-29 102.9 0.0 1.6e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFO96171.1 - 3.9e-14 52.4 0.0 5.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFO96171.1 - 6.9e-08 31.8 0.2 2e-07 30.3 0.1 1.9 1 1 0 1 1 1 1 KaiC RecA PF00154.16 KFO96171.1 - 1.9e-05 23.8 0.1 0.015 14.3 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein PAXNEB PF05625.6 KFO96171.1 - 0.00036 19.4 0.0 0.00067 18.5 0.0 1.4 1 0 0 1 1 1 1 PAXNEB protein DnaB_C PF03796.10 KFO96171.1 - 0.0013 17.7 0.1 0.048 12.5 0.0 2.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain SAM_2 PF07647.12 KFO96171.1 - 0.034 14.0 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA PF00004.24 KFO96171.1 - 0.084 13.0 0.0 0.38 10.9 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1113 PF06541.6 KFO96172.1 - 1.3e-10 41.2 11.6 1.6e-10 40.9 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1113) PIG-H PF10181.4 KFO96173.1 - 1.5e-16 59.7 0.3 2.2e-16 59.2 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Arginase PF00491.16 KFO96174.1 - 1.1e-70 238.1 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family V-SNARE_C PF12352.3 KFO96175.1 - 7.6e-21 73.9 8.2 7.6e-21 73.9 5.7 2.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 KFO96175.1 - 5.7e-13 48.8 4.7 5.7e-13 48.8 3.2 2.2 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 KFO96175.1 - 1.4e-05 24.6 1.9 1.4e-05 24.6 1.3 1.8 2 0 0 2 2 2 1 Sec20 SNARE PF05739.14 KFO96175.1 - 0.0036 16.9 0.8 0.0036 16.9 0.5 2.0 2 1 0 2 2 2 1 SNARE domain Laminin_II PF06009.7 KFO96175.1 - 0.0052 16.5 2.2 0.03 14.0 0.5 2.2 2 0 0 2 2 2 1 Laminin Domain II BSMAP PF12280.3 KFO96175.1 - 0.025 14.4 1.0 0.036 13.9 0.7 1.4 1 1 0 1 1 1 0 Brain specific membrane anchored protein Fusion_gly PF00523.13 KFO96175.1 - 0.13 10.2 3.7 0.1 10.6 1.1 1.7 1 1 1 2 2 2 0 Fusion glycoprotein F0 Prominin PF05478.6 KFO96175.1 - 0.32 8.4 3.6 0.17 9.4 0.6 1.7 2 0 0 2 2 2 0 Prominin DUF745 PF05335.8 KFO96175.1 - 0.39 10.2 3.9 3.7 7.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Apolipoprotein PF01442.13 KFO96175.1 - 2.7 7.4 10.1 5 6.5 0.6 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3958 PF13125.1 KFO96175.1 - 4.3 7.2 7.9 0.92 9.4 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) CTNNB1_binding PF08347.6 KFO96175.1 - 4.9 7.3 6.9 1.1 9.5 1.0 2.1 1 1 0 2 2 2 0 N-terminal CTNNB1 binding Snapin_Pallidin PF14712.1 KFO96175.1 - 5.1 7.4 11.5 0.88 9.9 0.3 2.7 2 1 0 2 2 2 0 Snapin/Pallidin TPR_2 PF07719.12 KFO96176.1 - 0.0034 17.1 0.2 0.019 14.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat PBP_GOBP PF01395.17 KFO96176.1 - 0.039 13.5 0.9 0.15 11.7 0.2 2.2 2 1 0 2 2 2 0 PBP/GOBP family FYVE PF01363.16 KFO96177.1 - 4.6e-17 61.6 15.9 8.9e-17 60.7 11.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFO96177.1 - 0.05 13.4 11.2 0.15 11.9 7.8 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2688 PF10892.3 KFO96177.1 - 0.41 10.3 4.8 0.89 9.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) zf-DHHC PF01529.15 KFO96177.1 - 2.1 7.7 9.5 0.18 11.2 3.1 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Gal-bind_lectin PF00337.17 KFO96179.1 - 9.3e-31 105.9 0.0 1e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin PH PF00169.24 KFO96180.1 - 8.2e-31 106.3 0.0 1.4e-16 60.5 0.0 2.4 2 0 0 2 2 2 2 PH domain DEP PF00610.16 KFO96180.1 - 1.6e-15 56.5 0.0 4.2e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_11 PF15413.1 KFO96180.1 - 1.1e-11 45.0 5.5 8.1e-05 22.8 0.1 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KFO96180.1 - 6.2e-08 32.8 0.1 0.012 15.7 0.1 3.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFO96180.1 - 0.0024 17.8 0.2 0.21 11.6 0.1 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 KFO96180.1 - 0.0028 17.4 0.1 1.9 8.3 0.0 2.7 3 0 0 3 3 3 2 PH domain PH_6 PF15406.1 KFO96180.1 - 0.026 14.5 0.0 1.2 9.2 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain EIF_2_alpha PF07541.7 KFO96181.1 - 3.4e-37 126.6 0.0 6.6e-37 125.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KFO96181.1 - 2.9e-15 56.1 0.7 7.4e-15 54.7 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Herpes_BLRF2 PF05812.7 KFO96181.1 - 0.14 11.9 1.8 6.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein ATP-synt_D PF01813.12 KFO96182.1 - 1.1e-66 224.1 8.6 1.4e-66 223.7 6.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Guanylate_kin PF00625.16 KFO96183.1 - 5.5e-51 172.6 0.0 1.4e-50 171.2 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase L27_N PF09060.5 KFO96183.1 - 1e-24 86.0 2.8 2.8e-24 84.6 1.9 1.8 1 0 0 1 1 1 1 L27_N SH3_2 PF07653.12 KFO96183.1 - 1.4e-12 46.8 0.0 3.6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.19 KFO96183.1 - 3.7e-12 46.2 0.4 8.6e-12 45.0 0.3 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 KFO96183.1 - 4.7e-09 35.7 1.1 1.4e-08 34.2 0.8 1.8 1 0 0 1 1 1 1 L27 domain SH3_1 PF00018.23 KFO96183.1 - 9.4e-07 28.1 0.3 3.2e-06 26.4 0.2 2.0 1 1 0 1 1 1 1 SH3 domain PDZ_2 PF13180.1 KFO96183.1 - 2e-06 27.5 0.1 6.4e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.1 KFO96183.1 - 2.5e-05 23.7 0.1 5.8e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain MMR_HSR1 PF01926.18 KFO96183.1 - 0.035 14.0 0.0 0.71 9.8 0.0 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase MoCF_biosynth PF00994.19 KFO96184.1 - 8.8e-68 226.2 0.0 1.9e-37 127.8 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KFO96184.1 - 6e-50 168.7 1.6 6.6e-50 168.6 0.2 1.7 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KFO96184.1 - 4.2e-23 81.0 0.0 1.1e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) BMF PF15185.1 KFO96185.1 - 7.4e-79 264.1 1.2 9e-79 263.8 0.8 1.1 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis SRP14 PF02290.10 KFO96186.1 - 4.8e-31 106.5 0.1 4.8e-31 106.5 0.1 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein 7tm_1 PF00001.16 KFO96187.1 - 6.8e-31 107.3 28.9 8.8e-31 106.9 20.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4083 PF13314.1 KFO96187.1 - 0.15 11.8 3.5 0.63 9.9 2.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) FSIP1 PF15554.1 KFO96188.1 - 4.4e-17 62.0 0.6 5.4e-17 61.7 0.4 1.1 1 0 0 1 1 1 1 FSIP1 family Leader_CPA1 PF08252.6 KFO96189.1 - 0.098 11.9 1.5 0.26 10.6 1.0 1.7 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide DUF1815 PF08844.5 KFO96189.1 - 0.13 11.8 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) TSP_C PF05735.7 KFO96190.1 - 3.9e-75 251.8 1.9 5.9e-75 251.2 1.3 1.3 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 KFO96190.1 - 7e-59 194.9 151.3 2.1e-12 46.2 9.4 10.3 9 2 2 11 11 11 9 Thrombospondin type 3 repeat TSP_1 PF00090.14 KFO96190.1 - 1.1e-38 131.0 46.8 4.6e-16 58.6 5.9 5.0 6 0 0 6 6 6 3 Thrombospondin type 1 domain VWC PF00093.13 KFO96190.1 - 9.1e-13 48.1 17.8 9.1e-13 48.1 12.4 6.6 4 3 1 5 5 5 1 von Willebrand factor type C domain cEGF PF12662.2 KFO96190.1 - 5.7e-07 29.0 1.5 5.7e-07 29.0 1.0 4.9 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.2 KFO96190.1 - 9.2e-07 28.7 10.4 9.2e-07 28.7 7.2 6.3 6 0 0 6 6 6 2 EGF domain EGF_CA PF07645.10 KFO96190.1 - 7.8e-06 25.7 2.2 7.8e-06 25.7 1.5 5.9 5 0 0 5 5 5 3 Calcium-binding EGF domain EGF PF00008.22 KFO96190.1 - 2.4e-05 24.1 42.2 0.00042 20.2 6.6 5.7 4 0 0 4 4 4 2 EGF-like domain Laminin_G_2 PF02210.19 KFO96190.1 - 0.022 14.7 0.2 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 Laminin G domain Katanin_con80 PF13925.1 KFO96191.1 - 2.6e-43 147.6 0.1 4.5e-43 146.8 0.1 1.4 1 0 0 1 1 1 1 con80 domain of Katanin DUF2012 PF09430.5 KFO96192.1 - 2.6e-30 104.7 0.1 3.4e-30 104.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 KFO96192.1 - 0.099 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain 7tm_1 PF00001.16 KFO96193.1 - 1.2e-87 293.2 5.4 1.6e-87 292.8 3.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFO96193.1 - 3e-08 33.1 7.7 3e-08 33.1 5.3 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MBT PF02820.13 KFO96194.1 - 1.4e-97 319.6 4.5 7.9e-34 115.4 0.0 3.1 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.13 KFO96194.1 - 0.001 18.7 7.7 0.001 18.7 5.3 2.1 3 0 0 3 3 3 1 Zinc finger, C2HC type Tudor-knot PF11717.3 KFO96194.1 - 0.72 9.6 6.6 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain DUF2371 PF10177.4 KFO96195.1 - 3.3e-57 192.3 0.0 1.4e-56 190.2 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) RbcS PF12338.3 KFO96195.1 - 0.035 13.8 0.5 0.13 12.0 0.3 2.0 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit DUF63 PF01889.12 KFO96195.1 - 0.12 12.3 0.1 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Membrane protein of unknown function DUF63 4_1_CTD PF05902.8 KFO96196.1 - 1.1e-33 115.7 7.3 1.1e-33 115.7 5.1 3.3 3 0 0 3 3 3 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 KFO96196.1 - 2.8e-27 94.1 1.9 1e-26 92.3 1.3 2.1 1 0 0 1 1 1 1 SAB domain FERM_C PF09380.5 KFO96196.1 - 1.1e-23 83.2 0.1 3.7e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFO96196.1 - 5.8e-22 77.5 0.4 3.8e-21 74.9 0.1 2.5 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 KFO96196.1 - 4.7e-20 72.0 0.1 4.7e-20 72.0 0.0 3.2 3 1 0 3 3 3 1 FERM central domain FA PF08736.6 KFO96196.1 - 9.5e-17 60.5 1.6 9.5e-17 60.5 1.1 2.9 3 0 0 3 3 3 1 FERM adjacent (FA) AKAP7_NLS PF10469.4 KFO96198.1 - 3.7e-40 137.8 0.9 5.8e-40 137.2 0.6 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain AKAP7_RIRII_bdg PF10470.4 KFO96198.1 - 1.1e-24 85.9 3.0 1.1e-24 85.9 2.0 2.0 2 0 0 2 2 2 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein 2_5_RNA_ligase2 PF13563.1 KFO96198.1 - 8.2e-07 28.8 0.1 1.8e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.7 KFO96198.1 - 0.0068 15.7 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Coronavirus NS2A protein LigT_PEase PF02834.11 KFO96198.1 - 0.1 12.5 0.2 3.2 7.7 0.0 2.7 3 1 0 3 3 3 0 LigT like Phosphoesterase MutS_V PF00488.16 KFO96199.1 - 6.4e-65 218.8 0.0 1e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFO96199.1 - 7.3e-31 107.5 0.4 1.2e-30 106.8 0.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KFO96199.1 - 5.4e-13 48.9 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 KFO96199.1 - 0.035 13.9 0.0 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Med23 PF11573.3 KFO96200.1 - 0 1939.5 11.4 0 1939.4 7.9 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Phosphodiest PF01663.17 KFO96201.1 - 3.5e-79 266.7 0.2 4.7e-79 266.3 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 KFO96201.1 - 6.1e-17 61.3 38.4 2.6e-09 36.8 8.7 3.0 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.18 KFO96201.1 - 6e-15 55.4 0.1 9.3e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Metalloenzyme PF01676.13 KFO96201.1 - 2.3e-05 23.8 0.0 3.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KFO96201.1 - 0.0024 17.0 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Sulfatase WD40 PF00400.27 KFO96202.1 - 3.5e-07 29.8 3.2 0.6 10.0 0.1 5.7 5 1 0 5 5 5 2 WD domain, G-beta repeat RVT_1 PF00078.22 KFO96202.1 - 3.2e-05 23.4 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MLANA PF14991.1 KFO96203.1 - 0.15 12.0 0.4 0.41 10.6 0.2 1.7 1 0 0 1 1 1 0 Protein melan-A RRM_1 PF00076.17 KFO96204.1 - 4.6e-66 218.4 0.0 3.1e-23 81.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96204.1 - 1.2e-35 121.2 0.0 1.2e-14 54.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96204.1 - 5.2e-31 106.2 0.3 8.6e-10 38.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KFO96204.1 - 2.4e-06 27.2 0.0 0.0037 16.8 0.0 3.0 3 0 0 3 3 3 2 Calcipressin Nup35_RRM_2 PF14605.1 KFO96204.1 - 1.5e-05 24.6 0.6 0.0089 15.7 0.0 3.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFO96204.1 - 0.0001 22.1 0.0 0.41 10.5 0.0 3.1 2 1 1 3 3 3 2 RNA binding motif Nup35_RRM PF05172.8 KFO96204.1 - 0.0023 17.6 0.2 0.13 12.0 0.1 3.1 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 KFO96204.1 - 0.046 13.7 0.1 6.5 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA binding domain DbpA PF03880.10 KFO96204.1 - 0.1 12.3 0.0 7.7 6.2 0.0 3.0 3 0 0 3 3 3 0 DbpA RNA binding domain HATPase_c PF02518.21 KFO96204.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prenylcys_lyase PF07156.9 KFO96205.1 - 9e-149 495.3 0.0 1e-148 495.1 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase DUF4561 PF15120.1 KFO96205.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4561) NGP1NT PF08153.7 KFO96205.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 NGP1NT (NUC091) domain LSM PF01423.17 KFO96206.1 - 3.3e-19 68.1 0.1 3.9e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain LRR_8 PF13855.1 KFO96208.1 - 6.6e-56 185.9 40.4 3.2e-14 52.4 0.9 5.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFO96208.1 - 8.1e-30 101.9 34.8 1.4e-07 31.0 2.8 6.4 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96208.1 - 2.8e-21 72.2 33.1 0.01 15.7 0.3 11.2 11 0 0 11 11 11 9 Leucine Rich Repeat LRR_5 PF13306.1 KFO96208.1 - 5.3e-20 71.4 1.1 1.7e-09 37.4 0.0 2.5 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO96208.1 - 2.1e-10 39.0 32.3 0.37 11.1 0.2 9.9 10 0 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 KFO96208.1 - 6.2e-09 35.0 31.0 0.47 10.6 0.4 9.2 9 1 0 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 KFO96208.1 - 2.4e-07 30.4 0.9 0.0075 15.8 0.1 2.7 1 1 2 3 3 3 2 Leucine-rich repeat LRRNT PF01462.13 KFO96208.1 - 0.026 13.9 3.4 0.051 13.0 1.3 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DUF3481 PF11980.3 KFO96208.1 - 0.062 13.1 1.1 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Viral_env_E26 PF11050.3 KFO96208.1 - 0.12 11.5 1.0 0.6 9.2 0.4 2.2 2 0 0 2 2 2 0 Virus envelope protein E26 Amidohydro_1 PF01979.15 KFO96209.1 - 2e-45 155.9 0.0 2.5e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFO96209.1 - 3.9e-12 46.7 0.0 5.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFO96209.1 - 1.9e-09 37.2 2.7 2.3e-09 36.9 0.4 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KFO96209.1 - 1.3e-05 24.6 0.9 0.0002 20.6 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family BNIP3 PF06553.7 KFO96210.1 - 2.1e-79 265.5 2.2 2.3e-79 265.3 1.5 1.0 1 0 0 1 1 1 1 BNIP3 WD40 PF00400.27 KFO96211.1 - 1.2e-14 53.5 3.0 0.76 9.7 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Y_phosphatase2 PF03162.8 KFO96211.1 - 0.031 13.6 0.5 0.98 8.7 0.0 2.6 2 0 0 2 2 2 0 Tyrosine phosphatase family TIG PF01833.19 KFO96212.1 - 4.4e-13 49.0 0.1 2e-12 46.9 0.0 2.2 1 0 0 1 1 1 1 IPT/TIG domain PP1_bind PF15276.1 KFO96213.1 - 1.3e-18 66.7 0.1 1.6e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 binding Pentapeptide PF00805.17 KFO96214.1 - 3.5e-40 134.6 29.9 3.9e-13 48.3 1.0 4.8 2 2 3 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 KFO96214.1 - 6.7e-22 77.0 1.8 1.6e-11 43.8 0.0 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 KFO96214.1 - 3e-20 72.2 0.0 4.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.1 KFO96214.1 - 5.5e-15 54.9 0.0 1.3e-05 24.9 0.0 4.6 1 1 1 3 3 3 3 Pentapeptide repeats (9 copies) DUF3354 PF11834.3 KFO96214.1 - 1e-14 53.8 0.1 1.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3354) BTB PF00651.26 KFO96214.1 - 3.4e-05 23.7 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain GnRH PF00446.12 KFO96215.1 - 0.0011 18.8 5.3 0.0022 17.9 3.7 1.5 1 0 0 1 1 1 1 Gonadotropin-releasing hormone Ded_cyto PF06920.8 KFO96216.1 - 1.9e-38 131.5 0.3 2.9e-38 130.9 0.2 1.3 1 0 0 1 1 1 1 Dedicator of cytokinesis DUF1160 PF06648.6 KFO96216.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) DOCK-C2 PF14429.1 KFO96218.1 - 2.7e-31 108.6 0.0 3.5e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Filament PF00038.16 KFO96219.1 - 1.4e-108 363.0 49.5 1.4e-108 363.0 34.3 2.8 2 0 0 2 2 2 1 Intermediate filament protein Filament_head PF04732.9 KFO96219.1 - 1.4e-11 44.9 12.3 1.4e-11 44.9 8.5 2.7 3 0 0 3 3 3 1 Intermediate filament head (DNA binding) region DUF1664 PF07889.7 KFO96219.1 - 0.0027 17.4 1.9 0.0027 17.4 1.3 4.5 5 1 2 7 7 7 2 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 KFO96219.1 - 0.065 13.4 0.5 0.065 13.4 0.4 4.1 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RNase_H PF00075.19 KFO96219.1 - 0.22 11.8 7.7 5.9 7.2 0.3 2.9 1 1 1 2 2 2 0 RNase H Reo_sigmaC PF04582.7 KFO96219.1 - 2.3 7.3 9.4 6.2 5.8 1.4 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KFO96219.1 - 2.7 7.7 13.7 8.3 6.2 0.9 3.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reprolysin PF01421.14 KFO96220.1 - 5e-71 238.4 0.1 5e-71 238.4 0.1 1.7 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFO96220.1 - 5.3e-27 94.1 0.1 7.5e-27 93.6 0.1 1.2 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFO96220.1 - 1.4e-23 82.8 30.1 1.4e-23 82.8 20.9 2.5 3 0 0 3 3 2 1 Disintegrin Reprolysin_5 PF13688.1 KFO96220.1 - 2.4e-20 73.3 2.9 7.2e-20 71.7 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFO96220.1 - 1.9e-18 66.7 0.3 4e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFO96220.1 - 2.6e-18 66.7 0.0 5.1e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFO96220.1 - 1.1e-12 48.3 0.6 2.5e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFO96220.1 - 0.00052 19.7 0.0 0.00069 19.3 0.0 1.2 1 0 0 1 1 1 1 Matrixin Astacin PF01400.19 KFO96220.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M43 PF05572.8 KFO96220.1 - 0.018 14.6 0.8 0.075 12.6 0.0 2.2 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A DUF3810 PF12725.2 KFO96220.1 - 0.019 13.9 0.2 0.019 13.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Peptidase_M66 PF10462.4 KFO96220.1 - 0.05 12.4 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M48 PF01435.13 KFO96220.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 WLM PF08325.5 KFO96220.1 - 0.21 11.4 1.0 0.38 10.5 0.7 1.3 1 0 0 1 1 1 0 WLM domain Stanniocalcin PF03298.8 KFO96221.1 - 4.6e-102 339.4 5.5 5.4e-102 339.1 3.8 1.0 1 0 0 1 1 1 1 Stanniocalcin family CD45 PF12567.3 KFO96221.1 - 0.78 9.6 6.5 8.5 6.3 0.0 3.3 3 0 0 3 3 3 0 Leukocyte receptor CD45 Homeobox PF00046.24 KFO96222.1 - 5.1e-22 77.2 4.1 5.8e-22 77.0 2.8 1.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFO96222.1 - 0.013 14.4 0.2 0.015 14.3 0.1 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFO96222.1 - 0.029 14.0 0.1 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Homeobox KN domain Mito_carr PF00153.22 KFO96223.1 - 1.3e-57 191.4 3.2 1.5e-20 72.7 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KFO96223.1 - 0.18 11.6 1.1 0.89 9.4 0.2 2.5 3 0 0 3 3 3 0 UcrQ family GDA1_CD39 PF01150.12 KFO96224.1 - 7.7e-91 304.7 0.0 1e-90 304.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Lysyl_oxidase PF01186.12 KFO96225.1 - 2e-87 292.1 2.6 4.3e-87 291.0 1.8 1.6 1 0 0 1 1 1 1 Lysyl oxidase SRCR PF00530.13 KFO96225.1 - 2.7e-83 274.6 41.3 2.6e-29 101.4 2.2 5.0 5 0 0 5 5 5 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFO96225.1 - 6.9e-23 80.7 12.7 2e-05 24.7 0.2 4.7 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.5 KFO96225.1 - 3.7e-05 23.8 7.1 1.8 8.8 0.0 4.8 5 0 0 5 5 5 2 Hepsin, SRCR R3H PF01424.17 KFO96226.1 - 8.2e-14 51.0 0.2 1.6e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 R3H domain DUF2414 PF10309.4 KFO96226.1 - 0.00014 21.4 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KFO96226.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Snf7 PF03357.16 KFO96227.1 - 4.8e-22 78.1 8.4 4.8e-22 78.1 5.8 2.1 2 0 0 2 2 2 1 Snf7 PspA_IM30 PF04012.7 KFO96227.1 - 1e-05 25.0 0.6 1e-05 25.0 0.4 2.2 2 0 0 2 2 2 1 PspA/IM30 family Allexi_40kDa PF05549.6 KFO96227.1 - 0.041 13.1 2.9 1.1 8.5 0.0 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Snapin_Pallidin PF14712.1 KFO96227.1 - 0.12 12.7 10.1 0.12 12.7 1.5 3.3 3 1 0 3 3 3 0 Snapin/Pallidin DUF342 PF03961.8 KFO96227.1 - 0.24 9.7 4.7 0.2 10.0 2.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2951 PF11166.3 KFO96227.1 - 7.1 6.5 7.8 10 6.0 0.1 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF2951) Death PF00531.17 KFO96228.1 - 5.6e-15 54.8 0.0 9.3e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.13 KFO96228.1 - 4.1e-08 33.1 46.7 8.8e-06 25.6 7.1 3.7 2 1 1 3 3 3 2 TNFR/NGFR cysteine-rich region Prominin PF05478.6 KFO96228.1 - 1.6 6.1 4.1 2.3 5.6 2.9 1.1 1 0 0 1 1 1 0 Prominin Ras PF00071.17 KFO96229.1 - 4.6e-25 87.8 0.0 9.6e-25 86.8 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFO96229.1 - 3.9e-13 49.9 0.0 6.3e-13 49.2 0.0 1.3 1 1 0 1 1 1 1 Miro-like protein PI-PLC-X PF00388.14 KFO96232.1 - 1.4e-64 215.9 0.1 2.7e-64 214.9 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.19 KFO96232.1 - 6e-46 154.1 0.6 2.2e-23 81.8 0.1 2.6 2 0 0 2 2 2 2 SH2 domain SH3_1 PF00018.23 KFO96232.1 - 5.2e-16 57.7 0.6 1.5e-15 56.2 0.4 1.9 1 0 0 1 1 1 1 SH3 domain C2 PF00168.25 KFO96232.1 - 3.2e-12 46.1 0.0 6.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.1 KFO96232.1 - 1e-11 44.2 0.3 1e-11 44.2 0.2 2.3 3 0 0 3 3 3 1 Variant SH3 domain PH PF00169.24 KFO96232.1 - 6.9e-10 39.0 1.4 0.00027 21.1 0.0 3.0 3 1 0 3 3 3 2 PH domain SH3_2 PF07653.12 KFO96232.1 - 2e-07 30.3 0.1 6.3e-07 28.7 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_like PF09279.6 KFO96232.1 - 6.3e-07 29.3 0.1 1.6e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-Y PF00387.14 KFO96232.1 - 1.3e-05 25.1 0.0 0.0004 20.3 0.0 2.6 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain GDPD PF03009.12 KFO96232.1 - 0.006 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family UCH PF00443.24 KFO96233.1 - 1.4e-05 24.3 2.1 0.00014 21.0 1.4 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MtlR PF05068.7 KFO96233.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Mannitol repressor NAPRTase PF04095.11 KFO96234.1 - 8.6e-22 77.6 0.0 3e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family EF1_GNE PF00736.14 KFO96235.1 - 2.1e-35 120.2 1.4 4.2e-35 119.3 1.0 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFO96235.1 - 4.3e-12 45.9 7.7 4.3e-12 45.9 5.4 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Striatin PF08232.7 KFO96235.1 - 0.00031 21.0 1.8 0.001 19.3 1.3 1.9 1 0 0 1 1 1 1 Striatin family TSC22 PF01166.13 KFO96235.1 - 0.027 14.4 0.4 0.096 12.6 0.3 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Lzipper-MIP1 PF14389.1 KFO96235.1 - 0.029 14.4 0.1 4.6 7.4 0.0 2.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MinC_N PF05209.8 KFO96235.1 - 0.085 12.6 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain Reo_sigmaC PF04582.7 KFO96235.1 - 0.12 11.5 0.4 0.18 10.9 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein WD40_alt PF14077.1 KFO96235.1 - 0.17 11.5 0.4 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif DDE_1 PF03184.14 KFO96236.1 - 9.9e-24 83.6 0.0 7.5e-18 64.4 0.0 2.5 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KFO96236.1 - 6.8e-18 64.2 0.4 1.5e-17 63.1 0.3 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KFO96236.1 - 1.7e-08 33.7 0.0 3.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.1 KFO96236.1 - 2.9e-05 23.9 0.6 0.00028 20.8 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 KFO96236.1 - 5.4e-05 22.6 0.9 0.00089 18.8 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 KFO96236.1 - 0.00012 21.9 0.9 0.00024 20.9 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 KFO96236.1 - 0.27 11.3 2.6 1.6 8.9 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix P5CR_dimer PF14748.1 KFO96237.1 - 1.2e-38 131.3 1.3 2.2e-38 130.5 0.9 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KFO96237.1 - 1.2e-06 28.8 0.2 9.6e-06 25.9 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KFO96237.1 - 0.00032 20.4 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KFO96237.1 - 0.047 13.1 0.1 0.095 12.1 0.0 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.1 KFO96237.1 - 0.07 13.2 0.0 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain Epimerase PF01370.16 KFO96238.1 - 1.9e-45 155.1 0.0 2.4e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFO96238.1 - 0.071 11.9 0.0 0.18 10.6 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Arrestin_N PF00339.24 KFO96239.1 - 4.3e-34 117.4 0.0 3.5e-33 114.5 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFO96239.1 - 1.1e-22 80.6 0.0 1.2e-17 64.3 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 KFO96239.1 - 0.004 15.9 0.0 0.022 13.5 0.0 2.1 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 BTB PF00651.26 KFO96240.1 - 1.9e-24 85.8 0.0 2.2e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFO96241.1 - 1.7e-14 53.2 17.3 5.4e-08 32.7 3.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO96241.1 - 2.5e-09 36.9 24.5 1.4e-05 25.0 4.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96241.1 - 3.8e-07 29.9 17.3 0.00018 21.5 1.8 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO96241.1 - 8e-05 22.6 13.7 0.00013 22.0 1.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 KFO96241.1 - 0.0012 18.5 1.7 0.0014 18.2 1.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-met PF12874.2 KFO96241.1 - 0.0018 18.3 2.1 0.0018 18.3 1.4 3.5 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-nanos PF05741.8 KFO96241.1 - 0.021 14.8 4.0 0.12 12.3 0.5 2.2 2 0 0 2 2 2 0 Nanos RNA binding domain DUF2225 PF09986.4 KFO96241.1 - 0.026 13.9 0.7 0.026 13.9 0.5 2.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-AN1 PF01428.11 KFO96241.1 - 0.046 13.5 10.8 0.058 13.2 2.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-Di19 PF05605.7 KFO96241.1 - 0.056 13.5 10.8 0.046 13.8 5.4 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-DNA_Pol PF08996.5 KFO96241.1 - 0.062 12.6 1.0 0.063 12.6 0.7 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-CHY PF05495.7 KFO96241.1 - 0.071 13.2 5.9 0.082 13.0 4.1 1.2 1 0 0 1 1 1 0 CHY zinc finger Prok-RING_1 PF14446.1 KFO96241.1 - 0.077 12.7 3.7 1.2 8.9 0.1 2.5 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 C1_4 PF07975.7 KFO96241.1 - 0.098 12.6 3.8 0.48 10.4 2.6 1.9 1 1 1 2 2 2 0 TFIIH C1-like domain Rtf2 PF04641.7 KFO96241.1 - 0.11 11.7 2.8 0.11 11.6 0.1 1.8 1 1 1 2 2 2 0 Rtf2 RING-finger Zn_Tnp_IS1595 PF12760.2 KFO96241.1 - 0.2 11.4 4.5 0.42 10.4 3.0 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF4428 PF14471.1 KFO96241.1 - 0.21 11.3 6.0 1.5 8.6 3.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-RING_5 PF14634.1 KFO96241.1 - 0.28 10.9 4.7 2.9 7.7 0.2 2.4 1 1 0 2 2 2 0 zinc-RING finger domain zf-C2H2_2 PF12756.2 KFO96241.1 - 0.29 11.2 10.5 1.2 9.2 6.7 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-CCHC_2 PF13696.1 KFO96241.1 - 0.3 10.6 4.2 0.31 10.5 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-TFIIB PF13453.1 KFO96241.1 - 0.39 9.9 1.7 0.68 9.1 1.2 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Rad50_zn_hook PF04423.9 KFO96241.1 - 0.43 10.0 2.3 0.68 9.4 0.1 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-RING_3 PF14369.1 KFO96241.1 - 0.44 10.5 3.0 9.7 6.2 0.1 2.3 2 0 0 2 2 2 0 zinc-finger Vps39_2 PF10367.4 KFO96241.1 - 0.45 10.7 4.4 1.7 8.8 0.1 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_6 PF13912.1 KFO96241.1 - 0.48 10.3 15.5 3 7.8 2.6 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger DUF2256 PF10013.4 KFO96241.1 - 0.5 10.1 4.4 2.8 7.7 0.1 2.5 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_4 PF13717.1 KFO96241.1 - 1.1 9.0 5.6 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFO96241.1 - 1.9 8.5 6.2 6.2 6.8 0.3 2.7 1 1 0 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.1 KFO96241.1 - 2.9 7.9 8.7 1.7 8.7 0.8 2.8 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-FCS PF06467.9 KFO96241.1 - 3.3 7.4 8.7 1.4 8.6 0.4 2.5 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Ribosomal_L32p PF01783.18 KFO96241.1 - 4.5 7.5 7.1 0.88 9.8 2.0 1.8 1 1 1 2 2 2 0 Ribosomal L32p protein family zf-C2HC_2 PF13913.1 KFO96241.1 - 8.6 6.1 9.5 3.3 7.4 0.2 2.7 3 0 0 3 3 2 0 zinc-finger of a C2HC-type Ribosomal_S13 PF00416.17 KFO96242.1 - 0.024 15.0 0.1 0.028 14.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Band_7 PF01145.20 KFO96243.1 - 3.5e-26 92.2 1.1 4.7e-26 91.7 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 KFO96243.1 - 0.021 14.8 0.4 0.033 14.2 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 zf-C2H2 PF00096.21 KFO96244.1 - 6.8e-37 123.5 67.6 1.3e-05 25.2 1.0 9.5 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO96244.1 - 1.6e-35 119.6 65.3 9.7e-09 35.1 1.0 9.6 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO96244.1 - 1.2e-22 78.4 54.2 7.3e-05 22.8 0.5 9.5 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO96244.1 - 4.2e-12 45.8 44.5 0.02 15.0 0.0 9.0 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO96244.1 - 9.6e-12 44.6 42.5 0.0019 18.3 0.1 8.6 8 0 0 8 8 8 4 Zinc-finger of C2H2 type RRN7 PF11781.3 KFO96244.1 - 0.011 15.2 17.9 1.4 8.4 0.1 6.7 7 0 0 7 7 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_6 PF13912.1 KFO96244.1 - 0.013 15.3 0.2 0.013 15.3 0.1 9.3 9 1 1 10 10 10 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFO96244.1 - 0.028 14.5 1.3 0.028 14.5 0.9 5.3 4 2 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFO96244.1 - 0.034 14.2 50.2 0.49 10.5 1.3 7.3 1 1 7 8 8 8 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.9 KFO96244.1 - 0.035 13.7 0.4 0.035 13.7 0.3 5.9 6 2 1 7 7 7 0 Adenylate kinase, active site lid zf-C2HC_2 PF13913.1 KFO96244.1 - 0.13 11.9 46.6 1.2 8.8 0.0 8.7 9 0 0 9 9 9 0 zinc-finger of a C2HC-type zf-FCS PF06467.9 KFO96244.1 - 0.14 11.7 33.0 0.038 13.6 1.0 7.1 6 1 2 8 8 8 0 MYM-type Zinc finger with FCS sequence motif BolA PF01722.13 KFO96244.1 - 0.17 11.8 6.3 7.1 6.6 0.0 3.6 3 1 0 3 3 3 0 BolA-like protein C1_4 PF07975.7 KFO96244.1 - 1.2 9.1 37.5 0.83 9.7 1.3 6.5 2 2 2 6 6 6 0 TFIIH C1-like domain Put_Phosphatase PF06888.7 KFO96245.1 - 6.4e-98 326.6 0.0 7.1e-98 326.4 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 KFO96245.1 - 3.4e-08 33.8 0.0 6.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFO96245.1 - 8.2e-05 22.8 0.0 0.00025 21.3 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.6 KFO96245.1 - 0.0037 16.7 0.3 0.22 10.9 0.1 2.4 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.21 KFO96245.1 - 0.0053 17.1 0.0 0.046 14.1 0.0 1.9 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KFO96245.1 - 0.15 11.7 0.1 0.54 9.9 0.0 2.0 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase G-gamma PF00631.17 KFO96246.1 - 2.8e-18 65.4 0.1 3e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain Herpes_UL25 PF01499.11 KFO96246.1 - 0.015 13.6 0.1 0.015 13.6 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF904 PF06005.7 KFO96246.1 - 0.018 15.3 1.8 0.02 15.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TPD52 PF04201.10 KFO96246.1 - 0.038 13.7 2.6 0.046 13.4 1.8 1.1 1 0 0 1 1 1 0 Tumour protein D52 family Bacillus_HBL PF05791.6 KFO96246.1 - 0.046 13.0 0.9 0.05 12.9 0.7 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Cwf_Cwc_15 PF04889.7 KFO96246.1 - 0.048 13.3 3.6 0.053 13.2 2.5 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma54_AID PF00309.15 KFO96246.1 - 0.1 12.1 0.2 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) PIN_4 PF13638.1 KFO96246.1 - 0.1 12.6 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 PIN domain HrpB7 PF09486.5 KFO96246.1 - 0.11 12.3 0.1 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) RBD-FIP PF09457.5 KFO96246.1 - 0.14 11.9 2.4 0.29 10.9 1.7 1.6 1 1 0 1 1 1 0 FIP domain KH_1 PF00013.24 KFO96247.1 - 3.9e-55 183.3 12.4 1.7e-13 50.0 0.2 4.5 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 KFO96247.1 - 3.1e-36 122.4 12.2 1.2e-08 34.4 0.1 4.7 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 KFO96247.1 - 2e-19 68.9 2.2 0.00049 19.6 0.0 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 KFO96247.1 - 1.5e-15 56.5 1.2 0.0016 18.0 0.0 5.0 5 0 0 5 5 5 4 KH domain KH_5 PF13184.1 KFO96247.1 - 3.1e-09 36.5 2.8 0.11 12.3 0.0 4.4 4 0 0 4 4 4 3 NusA-like KH domain RRM_1 PF00076.17 KFO96247.1 - 1.6e-08 34.0 0.0 3.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96247.1 - 7e-06 25.7 0.0 1.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96247.1 - 4e-05 23.5 0.0 8.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) dUTPase PF00692.14 KFO96247.1 - 0.064 12.7 0.1 23 4.4 0.0 3.1 4 0 0 4 4 4 0 dUTPase YtzH PF14165.1 KFO96247.1 - 0.11 12.7 3.8 0.85 9.8 0.2 3.2 3 1 1 4 4 4 0 YtzH-like protein Hormone_2 PF00123.15 KFO96248.1 - 9.8e-10 38.0 3.8 6.4e-07 29.0 0.1 3.2 3 0 0 3 3 3 3 Peptide hormone EAP30 PF04157.11 KFO96249.1 - 1.8e-66 223.5 0.1 2.1e-66 223.3 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF3702 PF12486.3 KFO96249.1 - 0.033 13.8 0.6 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 ImpA domain protein Apolipoprotein PF01442.13 KFO96249.1 - 0.042 13.3 4.8 0.072 12.6 0.2 2.4 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain TrmB PF01978.14 KFO96249.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF1342 PF07072.6 KFO96249.1 - 0.084 12.5 2.3 12 5.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1342) Sigma70_r1_1 PF03979.9 KFO96249.1 - 0.098 12.5 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 ATP-synt_C PF00137.16 KFO96250.1 - 5.2e-18 64.7 13.7 5.9e-18 64.5 9.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit C CALCOCO1 PF07888.6 KFO96251.1 - 4.2e-25 88.0 48.5 6e-25 87.5 26.9 2.6 1 1 1 2 2 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like GOLGA2L5 PF15070.1 KFO96251.1 - 1e-05 24.2 36.9 2e-05 23.3 25.3 1.5 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 WEMBL PF05701.6 KFO96251.1 - 6.2e-05 21.6 29.3 6.2e-05 21.6 20.3 2.0 2 0 0 2 2 2 1 Weak chloroplast movement under blue light TBPIP PF07106.8 KFO96251.1 - 0.0001 21.8 49.2 0.00021 20.8 12.7 3.1 1 1 1 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KFO96251.1 - 0.00013 21.6 27.1 0.00013 21.6 18.8 2.6 1 1 1 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 KFO96251.1 - 0.00057 19.1 11.5 0.0036 16.5 2.5 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein GAS PF13851.1 KFO96251.1 - 0.001 18.2 23.9 0.001 18.2 16.5 3.1 1 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding WD40_alt PF14077.1 KFO96251.1 - 0.0049 16.4 11.2 0.14 11.8 1.5 3.3 2 1 0 3 3 3 2 Alternative WD40 repeat motif bZIP_1 PF00170.16 KFO96251.1 - 0.0058 16.5 3.8 0.0058 16.5 2.6 6.2 2 1 4 6 6 6 3 bZIP transcription factor DUF904 PF06005.7 KFO96251.1 - 0.046 14.0 58.3 0.19 12.0 12.2 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF904) ERM PF00769.14 KFO96251.1 - 0.071 12.6 46.6 0.3 10.5 32.2 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family zf-C2H2_4 PF13894.1 KFO96251.1 - 0.092 13.1 1.6 3.7 8.1 0.1 3.1 1 1 1 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO96251.1 - 0.1 12.9 1.1 8 6.9 0.1 2.9 3 0 0 3 3 2 0 Zinc-finger double domain NPV_P10 PF05531.7 KFO96251.1 - 0.31 11.3 17.5 4.4 7.6 5.0 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein cwf18 PF08315.7 KFO96251.1 - 0.33 11.4 24.8 0.41 11.1 7.2 2.6 1 1 0 2 2 2 0 cwf18 pre-mRNA splicing factor HOOK PF05622.7 KFO96251.1 - 0.39 8.4 44.3 0.022 12.5 20.1 2.0 1 1 1 2 2 2 0 HOOK protein DUF972 PF06156.8 KFO96251.1 - 0.81 10.0 44.6 0.91 9.8 7.6 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF972) DivIC PF04977.10 KFO96251.1 - 0.99 8.9 44.6 0.41 10.1 4.3 6.2 3 2 4 7 7 7 0 Septum formation initiator FliD_N PF02465.13 KFO96251.1 - 1.9 8.8 13.0 4.6 7.6 0.7 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TraF_2 PF13729.1 KFO96251.1 - 2.1 7.0 4.2 4.5 5.9 0.2 2.2 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein EMP24_GP25L PF01105.19 KFO96251.1 - 3.1 7.4 25.1 8.1e+02 -0.5 13.8 4.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Macoilin PF09726.4 KFO96251.1 - 3.2 5.9 32.1 5 5.2 22.3 1.3 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2 PF00096.21 KFO96251.1 - 4.1 7.9 5.8 42 4.7 0.2 3.4 2 1 0 2 2 2 0 Zinc finger, C2H2 type MAD PF05557.8 KFO96251.1 - 8.4 4.3 47.4 10 4.0 24.3 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Homeobox PF00046.24 KFO96252.1 - 2.1e-19 68.8 5.3 2.4e-19 68.6 3.7 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO96252.1 - 0.00036 20.1 2.1 0.00053 19.6 1.5 1.3 1 0 0 1 1 1 1 Homeobox KN domain DUF1510 PF07423.6 KFO96252.1 - 0.023 14.0 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Homez PF11569.3 KFO96252.1 - 0.076 12.0 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Stc1 PF12898.2 KFO96252.1 - 0.21 11.6 0.8 0.35 10.9 0.3 1.6 1 1 1 2 2 2 0 Stc1 domain Hox9_act PF04617.8 KFO96253.1 - 3.3e-56 190.3 2.6 4.8e-56 189.8 1.8 1.2 1 0 0 1 1 1 1 Hox9 activation region Homeobox PF00046.24 KFO96253.1 - 2.5e-21 75.0 6.1 4e-21 74.3 4.2 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 KFO96253.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFO96254.1 - 3.1e-22 77.9 7.8 4.6e-22 77.3 5.4 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO96254.1 - 0.013 15.1 0.8 0.026 14.2 0.5 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFO96255.1 - 2.9e-22 78.0 8.5 4.5e-22 77.4 5.9 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO96255.1 - 0.02 14.5 1.1 0.045 13.4 0.7 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF4074 PF13293.1 KFO96257.1 - 7.2e-34 115.8 9.4 7.2e-34 115.8 6.5 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4074) Homeobox PF00046.24 KFO96257.1 - 1.5e-14 53.3 4.8 1.5e-14 53.3 3.3 1.8 2 0 0 2 2 2 1 Homeobox domain Homeobox PF00046.24 KFO96258.1 - 1e-22 79.4 7.2 1.4e-22 79.0 5.0 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO96258.1 - 0.17 11.6 1.6 0.32 10.7 0.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain PX PF00787.19 KFO96259.1 - 1.6e-25 89.0 0.5 1.9e-25 88.8 0.3 1.1 1 0 0 1 1 1 1 PX domain DoxD PF04173.8 KFO96259.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD Chromo_shadow PF01393.14 KFO96260.1 - 4.5e-39 132.0 0.1 3.8e-34 116.3 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 KFO96260.1 - 4.7e-24 83.8 3.9 4.6e-19 67.8 0.4 2.9 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KFO96260.1 - 0.0022 17.8 0.1 0.0056 16.5 0.2 1.6 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 DUF2201_N PF13203.1 KFO96260.1 - 0.27 10.3 2.7 0.3 10.2 1.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Ribosomal_L22 PF00237.14 KFO96261.1 - 3e-35 120.3 0.0 5e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4512 PF14975.1 KFO96262.1 - 3.1e-17 63.1 3.4 3.5e-17 62.9 2.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) Dymeclin PF09742.4 KFO96263.1 - 5.2e-10 38.0 0.1 5.4e-10 38.0 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Cadherin PF00028.12 KFO96264.1 - 6e-50 167.4 0.0 9.1e-20 70.7 0.0 4.1 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.7 KFO96264.1 - 0.072 12.6 0.1 1.3 8.6 0.0 2.8 2 1 0 2 2 2 0 Cadherin-like Trefoil PF00088.13 KFO96265.1 - 0.98 9.1 6.7 17 5.1 0.7 3.1 1 1 2 3 3 3 0 Trefoil (P-type) domain E1-E2_ATPase PF00122.15 KFO96266.1 - 1.2e-20 73.5 0.5 1.6e-20 73.1 0.1 1.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KFO96266.1 - 2.5e-11 42.8 0.0 4.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus BCCT PF02028.12 KFO96266.1 - 0.029 12.6 0.1 0.035 12.3 0.0 1.0 1 0 0 1 1 1 0 BCCT family transporter MARVEL PF01284.18 KFO96266.1 - 0.033 13.9 0.6 0.04 13.7 0.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain Tetraspannin PF00335.15 KFO96266.1 - 0.22 10.7 2.2 0.26 10.5 1.5 1.1 1 0 0 1 1 1 0 Tetraspanin family E1-E2_ATPase PF00122.15 KFO96267.1 - 4.1e-27 94.7 0.4 4.7e-27 94.5 0.3 1.0 1 0 0 1 1 1 1 E1-E2 ATPase Tektin PF03148.9 KFO96268.1 - 5.6e-140 466.2 29.8 6.4e-140 466.0 20.6 1.0 1 0 0 1 1 1 1 Tektin family Sin3_corepress PF08295.7 KFO96268.1 - 0.11 12.3 2.8 2.6 7.8 0.2 3.3 3 0 0 3 3 3 0 Sin3 family co-repressor BLOC1_2 PF10046.4 KFO96268.1 - 4.5 7.4 10.1 0.46 10.6 0.8 3.4 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 dUTPase PF00692.14 KFO96269.1 - 3.2e-19 68.6 0.0 4.1e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFO96269.1 - 0.0051 16.7 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF3312 PF11768.3 KFO96271.1 - 0.0093 14.2 0.1 0.027 12.7 0.0 1.6 1 1 0 2 2 2 1 Protein of unknown function (DUF3312) DUF3639 PF12341.3 KFO96271.1 - 0.048 13.6 0.1 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) Ala_racemase_N PF01168.15 KFO96272.1 - 2.6e-05 23.8 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain SET PF00856.23 KFO96273.1 - 7.9e-25 88.0 0.1 7.9e-25 88.0 0.0 4.6 4 2 1 5 5 5 1 SET domain SRI PF08236.6 KFO96273.1 - 5.1e-13 48.7 2.2 1.9e-12 46.9 1.5 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 KFO96273.1 - 4.2e-10 39.3 3.7 1.5e-09 37.4 2.5 2.1 1 0 0 1 1 1 1 WW domain Kinesin PF00225.18 KFO96274.1 - 2.1e-76 256.7 0.2 5.8e-76 255.3 0.1 1.8 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 KFO96274.1 - 0.0066 16.5 4.6 0.0086 16.2 0.0 3.4 5 0 0 5 5 5 1 AAA domain Atg14 PF10186.4 KFO96274.1 - 0.38 9.6 14.6 0.29 10.0 8.8 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 KFO96274.1 - 3.9 7.4 12.6 9.9 6.0 8.8 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PAP2 PF01569.16 KFO96275.1 - 1.3e-20 73.4 1.2 1.3e-20 73.4 0.8 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KFO96275.1 - 3.7e-06 27.1 1.5 3.7e-06 27.1 1.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily C-terminal YhhN PF07947.9 KFO96275.1 - 0.0082 15.5 0.7 0.016 14.5 0.5 1.5 1 0 0 1 1 1 1 YhhN-like protein Antimicrobial13 PF08108.6 KFO96275.1 - 0.2 11.5 1.1 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 Halocidin family Pkinase PF00069.20 KFO96276.1 - 3.7e-68 229.4 0.0 4.8e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96276.1 - 1.2e-36 126.0 0.0 2.2e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO96276.1 - 4.6e-06 25.8 0.0 6.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFO96276.1 - 0.00014 21.3 0.3 0.0005 19.4 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KFO96276.1 - 0.002 17.2 0.2 0.0044 16.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO96276.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.4 KFO96276.1 - 0.14 10.6 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC hSH3 PF14603.1 KFO96277.1 - 1.1e-12 47.8 0.0 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.12 KFO96277.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Sec62 PF03839.11 KFO96277.1 - 0.69 9.2 5.8 0.76 9.1 4.0 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 MACPF PF01823.14 KFO96278.1 - 1.2e-48 165.5 0.9 9.1e-48 162.7 0.0 2.0 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.13 KFO96278.1 - 3e-10 39.8 12.1 1.6e-09 37.4 8.4 2.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 KFO96278.1 - 0.0017 18.3 10.4 0.0017 18.3 7.2 3.8 4 1 0 4 4 4 2 Thrombospondin type 1 domain hEGF PF12661.2 KFO96278.1 - 3.4 7.9 17.0 0.26 11.4 4.1 3.6 3 0 0 3 3 3 0 Human growth factor-like EGF MACPF PF01823.14 KFO96279.1 - 9.2e-42 143.1 0.1 2.8e-41 141.5 0.0 1.8 2 0 0 2 2 2 1 MAC/Perforin domain Ldl_recept_a PF00057.13 KFO96279.1 - 3.9e-08 33.0 10.8 1.3e-07 31.3 7.5 2.0 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A hEGF PF12661.2 KFO96279.1 - 0.28 11.3 9.8 0.041 13.9 1.4 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF PID PF00640.18 KFO96280.1 - 5.9e-24 84.6 0.1 9.5e-24 83.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Bac_globin PF01152.16 KFO96280.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial-like globin Peptidase_M48 PF01435.13 KFO96281.1 - 2e-31 109.3 0.1 2.7e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 KFO96281.1 - 0.036 13.2 0.2 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain EamA PF00892.15 KFO96281.1 - 0.39 10.7 3.7 1.3 9.1 0.1 2.6 2 1 1 3 3 3 0 EamA-like transporter family Peptidase_U49 PF10463.4 KFO96281.1 - 1.4 8.6 5.1 1.4 8.6 1.0 2.4 2 1 1 3 3 3 0 Peptidase U49 SWIRM PF04433.12 KFO96282.1 - 1.6e-21 76.2 0.0 4.4e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain JAB PF01398.16 KFO96282.1 - 3e-13 49.5 0.0 8.3e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.26 KFO96282.1 - 6.4e-12 45.3 0.2 1.6e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Prok-JAB PF14464.1 KFO96282.1 - 1.5e-09 37.3 0.0 4.1e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.1 KFO96282.1 - 6.3e-07 29.4 0.4 2e-06 27.7 0.3 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0172 PF03665.8 KFO96282.1 - 0.0064 16.0 0.3 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) Ank_2 PF12796.2 KFO96283.1 - 4.2e-142 462.9 50.3 2.8e-23 82.0 0.4 8.1 2 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KFO96283.1 - 5.4e-98 316.2 42.1 2e-08 33.6 0.3 16.2 16 1 1 17 17 17 14 Ankyrin repeat Ank_4 PF13637.1 KFO96283.1 - 1.2e-81 267.8 12.3 4.1e-12 46.2 0.0 11.8 8 3 4 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO96283.1 - 2.2e-74 243.7 20.5 3.9e-11 42.8 0.1 13.0 3 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO96283.1 - 5.1e-71 227.4 27.5 1.8e-05 24.5 0.0 15.6 15 1 0 15 15 15 14 Ankyrin repeat Jun PF03957.8 KFO96284.1 - 6.5e-89 297.7 12.2 8.8e-89 297.2 8.5 1.2 1 0 0 1 1 1 1 Jun-like transcription factor bZIP_1 PF00170.16 KFO96284.1 - 1.1e-19 70.1 18.0 2.1e-19 69.2 12.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFO96284.1 - 2.3e-09 36.9 15.2 5.4e-09 35.7 10.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFO96284.1 - 6.3e-09 36.0 9.3 1.3e-08 35.0 6.5 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF3450 PF11932.3 KFO96284.1 - 0.0022 17.3 1.1 0.0033 16.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PspA_IM30 PF04012.7 KFO96284.1 - 0.0061 15.9 6.7 0.0063 15.9 4.0 1.4 1 1 0 1 1 1 1 PspA/IM30 family HAP1_N PF04849.8 KFO96284.1 - 0.0071 15.3 4.1 0.011 14.7 2.8 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region FlaC_arch PF05377.6 KFO96284.1 - 0.011 15.6 1.5 0.028 14.2 1.0 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 KFO96284.1 - 0.024 14.9 5.7 0.024 14.9 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KFO96284.1 - 0.077 12.8 6.2 0.073 12.8 3.3 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KFO96284.1 - 0.096 12.2 2.3 0.16 11.5 1.6 1.3 1 0 0 1 1 1 0 IncA protein Jnk-SapK_ap_N PF09744.4 KFO96284.1 - 0.1 12.6 5.1 0.16 11.9 3.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Antimicrobial_7 PF08102.6 KFO96284.1 - 0.32 11.0 3.1 8.7 6.4 0.4 3.0 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Seryl_tRNA_N PF02403.17 KFO96284.1 - 0.49 10.4 7.5 0.95 9.5 5.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Striatin PF08232.7 KFO96284.1 - 1.5 9.1 10.6 13 6.1 7.3 2.1 1 1 0 1 1 1 0 Striatin family DUF4140 PF13600.1 KFO96284.1 - 2.7 8.4 6.1 27 5.2 3.9 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 KFO96284.1 - 3.9 7.0 8.0 1.3 8.5 2.9 2.1 1 1 1 2 2 2 0 Septum formation initiator FGGY_C PF02782.11 KFO96285.1 - 1.5e-46 158.5 0.1 2.2e-46 157.9 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFO96285.1 - 1.9e-29 102.7 0.0 2.6e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KFO96285.1 - 0.0014 17.9 0.1 0.033 13.4 0.0 2.6 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family UPF0075 PF03702.9 KFO96285.1 - 0.059 12.2 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) HSP70 PF00012.15 KFO96285.1 - 0.073 10.9 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein zf-RING_2 PF13639.1 KFO96286.1 - 2.4e-10 40.0 8.6 3.9e-10 39.4 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFO96286.1 - 4.3e-10 39.0 7.0 7.4e-10 38.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFO96286.1 - 8e-10 38.4 6.5 8e-10 38.4 4.5 1.9 2 1 1 3 3 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KFO96286.1 - 1.4e-09 37.5 3.1 2e-09 36.9 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO96286.1 - 6.1e-09 35.7 8.7 1e-08 35.0 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFO96286.1 - 1.1e-05 25.0 2.1 1.1e-05 25.0 1.4 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFO96286.1 - 5.2e-05 22.8 10.1 9.7e-05 22.0 5.7 2.3 2 1 1 3 3 2 1 zinc-RING finger domain zf-Sec23_Sec24 PF04810.10 KFO96286.1 - 0.0044 16.5 2.7 1 8.9 0.0 2.5 2 1 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RING_4 PF14570.1 KFO96286.1 - 0.012 15.1 3.0 0.15 11.6 1.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KFO96286.1 - 0.022 14.5 4.8 0.12 12.2 3.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 KFO96286.1 - 0.024 14.5 4.1 0.04 13.8 2.8 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain zf-Nse PF11789.3 KFO96286.1 - 0.024 14.1 3.1 0.049 13.1 2.1 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KFO96286.1 - 0.031 13.7 8.6 0.057 12.9 6.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 KFO96286.1 - 0.054 13.6 7.7 0.38 10.8 5.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Zn_Tnp_IS1 PF03811.8 KFO96286.1 - 0.098 12.1 1.1 15 5.1 0.0 2.6 2 0 0 2 2 2 0 InsA N-terminal domain zf-B_box PF00643.19 KFO96286.1 - 0.1 12.4 5.1 1.3 8.9 0.3 3.1 3 0 0 3 3 3 0 B-box zinc finger zf-met2 PF12907.2 KFO96286.1 - 0.14 12.1 1.9 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding Baculo_IE-1 PF05290.6 KFO96286.1 - 0.18 11.5 6.5 0.19 11.4 4.1 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Elf1 PF05129.8 KFO96286.1 - 0.3 10.8 6.6 0.28 10.9 0.8 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.11 KFO96286.1 - 0.72 9.7 4.3 2 8.3 0.7 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger Cys_rich_CPXG PF14255.1 KFO96286.1 - 1.2 9.0 4.0 8.1 6.3 0.2 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG DZR PF12773.2 KFO96286.1 - 1.3 8.9 7.0 20 5.0 0.1 2.7 1 1 0 2 2 2 0 Double zinc ribbon Fer2 PF00111.22 KFO96286.1 - 1.4 8.7 4.6 0.47 10.2 0.5 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-Di19 PF05605.7 KFO96286.1 - 2 8.5 6.7 71 3.6 4.6 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 KFO96286.1 - 3.2 7.8 8.6 2.6 8.1 0.1 2.7 2 1 0 2 2 2 0 zinc-finger zf-H2C2_2 PF13465.1 KFO96286.1 - 3.6 8.0 5.3 56 4.2 1.4 2.9 2 1 0 2 2 2 0 Zinc-finger double domain Lar_restr_allev PF14354.1 KFO96286.1 - 5 7.4 6.5 51 4.2 4.5 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar RPA_interact_C PF14768.1 KFO96286.1 - 6.6 7.2 7.3 22 5.5 1.2 2.2 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Prok-RING_4 PF14447.1 KFO96286.1 - 7.8 6.1 11.6 3.6e+02 0.7 8.1 3.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Auto_anti-p27 PF06677.7 KFO96286.1 - 8.6 6.2 7.8 19 5.1 0.0 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) p450 PF00067.17 KFO96287.1 - 8.7e-131 436.6 0.2 1e-130 436.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFO96288.1 - 2.7e-41 141.5 0.1 2.9e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFO96289.1 - 6.9e-10 38.0 0.5 7e-10 38.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhnA PF03831.9 KFO96290.1 - 0.11 11.8 0.1 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 PhnA protein CTF_NFI PF00859.13 KFO96291.1 - 4.3e-113 377.9 30.5 7.9e-113 377.0 21.2 1.4 1 1 0 1 1 1 1 CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N PF10524.4 KFO96291.1 - 7.7e-26 89.4 5.1 1.4e-25 88.5 3.5 1.5 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.11 KFO96291.1 - 5.1e-12 45.7 0.1 9.4e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 MH1 domain TM2 PF05154.11 KFO96292.1 - 8.6e-18 64.2 5.6 1.3e-17 63.6 3.9 1.3 1 0 0 1 1 1 1 TM2 domain Ank_2 PF12796.2 KFO96293.1 - 9.5e-24 83.5 2.5 1.5e-16 60.4 0.2 2.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFO96293.1 - 1.1e-22 79.5 5.8 1.3e-13 50.6 0.2 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFO96293.1 - 1.1e-21 75.5 2.7 5.4e-06 25.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFO96293.1 - 3.2e-20 72.0 5.5 1.1e-08 35.3 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO96293.1 - 5.3e-17 60.2 0.2 0.00053 19.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat UCH PF00443.24 KFO96295.1 - 3.3e-41 141.1 13.1 7.8e-34 117.0 8.1 3.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO96295.1 - 1.5e-19 70.6 1.7 4.5e-17 62.4 1.3 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ded_cyto PF06920.8 KFO96296.1 - 2.7e-78 261.3 2.7 3.2e-78 261.1 0.8 2.1 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFO96296.1 - 1.1e-55 188.1 0.1 4.1e-55 186.2 0.1 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 KFO96296.1 - 2.3e-34 117.1 0.1 1.3e-32 111.5 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) Fibrinogen_C PF00147.13 KFO96297.1 - 4.7e-54 183.4 1.1 8.2e-54 182.6 0.8 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Reo_sigmaC PF04582.7 KFO96297.1 - 0.00097 18.4 1.7 0.0014 17.8 1.2 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein EF1_GNE PF00736.14 KFO96297.1 - 0.092 12.4 4.4 0.58 9.8 0.2 2.7 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain FlaC_arch PF05377.6 KFO96297.1 - 0.095 12.6 0.3 0.095 12.6 0.2 3.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 KFO96297.1 - 0.51 10.1 11.9 0.19 11.5 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RTBV_P46 PF06216.6 KFO96297.1 - 0.8 8.4 9.2 0.075 11.8 1.7 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein IncA PF04156.9 KFO96297.1 - 1.7 8.1 23.6 29 4.2 16.3 2.1 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 KFO96297.1 - 2.2 8.6 15.9 1.2e+02 3.1 11.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) WXG100 PF06013.7 KFO96297.1 - 3.1 7.8 10.3 0.33 10.9 1.1 3.0 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Sec34 PF04136.10 KFO96297.1 - 4.5 6.9 12.7 0.15 11.7 2.8 2.3 1 1 0 2 2 2 0 Sec34-like family Peptidase_C54 PF03416.14 KFO96298.1 - 2.5e-113 377.8 0.0 3.4e-113 377.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 CENP-R PF06729.7 KFO96299.1 - 2.1e-56 189.4 0.8 2.5e-56 189.2 0.5 1.0 1 0 0 1 1 1 1 Kinetochore component, CENP-R EF-hand_7 PF13499.1 KFO96300.1 - 4.8e-16 58.6 2.3 2.7e-08 33.8 0.8 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KFO96300.1 - 2.8e-12 45.0 3.2 0.0015 17.7 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFO96300.1 - 1.4e-09 37.4 7.1 6.1e-06 25.7 0.0 4.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFO96300.1 - 9e-08 31.3 4.7 0.0012 18.4 0.0 4.6 3 2 2 5 5 5 2 EF-hand domain EF-hand_5 PF13202.1 KFO96300.1 - 1.8e-05 23.8 1.9 0.11 11.8 0.2 3.2 3 0 0 3 3 3 2 EF hand EF_assoc_2 PF08356.7 KFO96300.1 - 0.035 13.8 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 EF hand associated UPF0154 PF03672.8 KFO96300.1 - 0.065 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KFO96300.1 - 0.072 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.2 KFO96300.1 - 0.081 12.6 1.5 2.9 7.6 0.0 3.2 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFO96300.1 - 0.12 12.2 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain PGM_PMM_I PF02878.11 KFO96301.1 - 5.6e-38 129.5 0.2 9.3e-38 128.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KFO96301.1 - 8.9e-31 106.2 0.0 1.6e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KFO96301.1 - 2.3e-18 66.4 0.0 5.8e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFO96301.1 - 7.5e-10 38.6 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase_Tyr PF07714.12 KFO96302.1 - 7.4e-89 297.2 0.0 9.4e-89 296.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO96302.1 - 1.6e-42 145.4 0.0 2.2e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Fz PF01392.17 KFO96302.1 - 4.2e-24 85.1 4.9 4.2e-24 85.1 3.4 2.1 3 0 0 3 3 3 1 Fz domain Kringle PF00051.13 KFO96302.1 - 2.5e-23 81.9 4.9 6.4e-23 80.6 3.4 1.8 1 0 0 1 1 1 1 Kringle domain I-set PF07679.11 KFO96302.1 - 1.5e-17 63.2 0.0 2.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96302.1 - 1.5e-09 37.8 0.1 3.6e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO96302.1 - 2.1e-08 34.1 0.0 5.4e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO96302.1 - 1.1e-07 32.2 1.4 1.9e-07 31.4 0.1 2.2 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFO96302.1 - 3.4e-05 23.7 0.0 0.00013 21.8 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain TMEM154 PF15102.1 KFO96302.1 - 0.039 13.6 0.0 0.039 13.6 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family VWA_N PF08399.6 KFO96303.1 - 5.5e-29 101.2 0.1 4.2e-28 98.4 0.0 2.4 2 0 0 2 2 2 1 VWA N-terminal Cache_1 PF02743.13 KFO96303.1 - 1.2e-16 59.9 0.1 6e-10 38.5 0.0 3.0 2 1 0 2 2 2 2 Cache domain VWA PF00092.23 KFO96303.1 - 1.6e-05 24.6 1.9 2.7e-05 23.9 1.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFO96303.1 - 0.038 13.6 0.1 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain RRM_1 PF00076.17 KFO96304.1 - 2.7e-25 87.7 1.9 4.4e-13 48.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96304.1 - 6.6e-18 64.4 0.1 3.1e-07 30.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96304.1 - 1.6e-16 59.9 0.6 0.00011 21.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.12 KFO96305.1 - 1.8e-127 423.8 0.0 1.1e-83 280.2 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFO96305.1 - 1.8e-64 217.4 0.0 2.2e-45 154.8 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain SH2 PF00017.19 KFO96305.1 - 6e-05 22.7 0.1 0.00021 20.9 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Kinase-like PF14531.1 KFO96305.1 - 7.1e-05 21.9 0.0 0.00095 18.2 0.0 2.3 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KFO96305.1 - 0.0099 15.2 0.1 0.056 12.7 0.0 2.3 2 0 0 2 2 2 1 RIO1 family ADK PF00406.17 KFO96306.1 - 2.6e-27 95.5 0.1 1.4e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KFO96306.1 - 1.4e-13 50.2 0.0 2.9e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KFO96306.1 - 6.8e-08 33.3 0.0 2.2e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFO96306.1 - 7.2e-05 23.1 0.2 0.019 15.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFO96306.1 - 0.00047 20.0 0.1 0.0047 16.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFO96306.1 - 0.039 14.1 0.1 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFO96306.1 - 0.07 12.8 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain PTEN_C2 PF10409.4 KFO96307.1 - 1.2e-25 89.8 0.0 2.1e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DnaJ PF00226.26 KFO96307.1 - 5.1e-07 29.3 0.0 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase PF00102.22 KFO96307.1 - 0.00072 18.9 0.1 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Vps55 PF04133.9 KFO96308.1 - 3.9e-39 133.1 4.4 4.3e-39 132.9 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 YwiC PF14256.1 KFO96308.1 - 0.39 10.8 4.3 0.71 9.9 3.0 1.5 1 1 0 1 1 1 0 YwiC-like protein MtN3_slv PF03083.11 KFO96308.1 - 4.3 7.2 6.5 2.6 7.9 0.4 2.5 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange Lep_receptor_Ig PF06328.6 KFO96309.1 - 7.1e-26 89.9 0.2 2.4e-25 88.1 0.1 2.0 1 0 0 1 1 1 1 Ig-like C2-type domain fn3 PF00041.16 KFO96309.1 - 1.3e-05 25.2 4.8 0.0026 17.8 0.0 4.5 4 0 0 4 4 4 1 Fibronectin type III domain PDEase_I PF00233.14 KFO96311.1 - 1.4e-106 355.6 6.9 1.4e-106 355.6 4.8 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DFP PF04127.10 KFO96311.1 - 0.13 11.8 2.6 0.087 12.4 0.2 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein YlqD PF11068.3 KFO96311.1 - 0.18 11.8 4.2 0.43 10.6 2.9 1.7 1 0 0 1 1 1 0 YlqD protein Tctex-1 PF03645.8 KFO96312.1 - 1.5e-26 92.1 0.1 1.7e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Insulin PF00049.13 KFO96313.1 - 0.017 15.8 0.1 0.019 15.7 0.1 1.1 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family Ins_beta PF03488.9 KFO96313.1 - 0.033 13.9 0.3 0.038 13.8 0.2 1.1 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type WD40 PF00400.27 KFO96314.1 - 3.2e-18 64.8 5.0 2.4e-07 30.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1830 PF08865.6 KFO96314.1 - 0.0089 15.6 0.3 0.084 12.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1830) DUF508 PF04370.7 KFO96314.1 - 0.01 15.4 0.2 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF3312 PF11768.3 KFO96314.1 - 0.19 9.9 0.0 0.3 9.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF2849 PF11011.3 KFO96314.1 - 0.31 11.3 3.4 22 5.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) Ribosomal_60s PF00428.14 KFO96314.1 - 6.9 7.1 13.1 0.24 11.8 3.9 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein ELM2 PF01448.19 KFO96315.1 - 8.1e-13 48.8 2.4 1.7e-12 47.8 0.0 2.7 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 KFO96315.1 - 0.00011 22.1 0.1 0.00026 20.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPT PF03151.11 KFO96316.1 - 1e-13 51.2 8.8 1e-13 51.2 6.1 2.0 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFO96316.1 - 0.0061 16.5 16.7 0.26 11.3 4.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KFO96316.1 - 0.014 14.3 15.5 0.026 13.4 10.7 1.4 1 1 0 1 1 1 0 UAA transporter family C2-set_2 PF08205.7 KFO96318.1 - 0.61 10.0 3.5 0.27 11.1 0.2 1.9 1 1 0 2 2 2 0 CD80-like C2-set immunoglobulin domain HABP4_PAI-RBP1 PF04774.10 KFO96319.1 - 2.5e-36 124.4 12.0 2.5e-36 124.4 8.3 2.2 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family G-gamma PF00631.17 KFO96320.1 - 2.8e-17 62.2 0.0 3.2e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 GGL domain Ras PF00071.17 KFO96321.1 - 9.8e-47 158.3 0.1 1.2e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO96321.1 - 9.4e-24 84.1 0.4 2e-23 83.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFO96321.1 - 2.9e-07 29.8 0.0 4.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO96321.1 - 0.00025 20.5 0.1 0.00067 19.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFO96321.1 - 0.00055 19.1 1.1 0.0027 16.9 0.0 1.9 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 KFO96321.1 - 0.00086 18.1 0.3 0.17 10.6 0.1 2.2 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 KFO96321.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFO96321.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFO96321.1 - 0.01 15.1 0.3 0.076 12.2 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_32 PF13654.1 KFO96321.1 - 0.013 14.2 1.2 0.3 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFO96321.1 - 0.023 13.9 0.7 0.058 12.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KFO96321.1 - 0.028 13.9 0.2 0.042 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Glyco_tran_WbsX PF14307.1 KFO96321.1 - 0.029 13.5 0.2 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX Arch_ATPase PF01637.13 KFO96321.1 - 0.054 13.1 0.1 0.09 12.4 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 KFO96321.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FGF PF00167.13 KFO96321.1 - 0.08 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Fibroblast growth factor AAA_16 PF13191.1 KFO96321.1 - 0.087 12.8 0.5 0.18 11.7 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain MIG-14_Wnt-bd PF06664.7 KFO96322.1 - 1.5e-91 306.3 17.3 1.9e-91 305.9 12.0 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Carboxyl_trans PF01039.17 KFO96323.1 - 1.3e-97 327.2 0.0 1.8e-97 326.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain RPE65 PF03055.10 KFO96324.1 - 1.4e-123 413.0 0.0 1.6e-123 412.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DEP PF00610.16 KFO96325.1 - 6.9e-18 64.1 0.0 2.4e-17 62.4 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 KFO96325.1 - 0.00086 18.9 4.6 0.2 11.2 0.0 3.3 3 0 0 3 3 3 2 RhoGAP domain DUF148 PF02520.12 KFO96325.1 - 0.027 14.2 1.7 0.069 12.9 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 LRR_4 PF12799.2 KFO96326.1 - 1.3e-62 206.5 77.2 4e-09 35.8 0.5 11.9 4 3 9 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO96326.1 - 1.7e-53 178.2 106.8 1.7e-11 43.6 5.4 9.9 4 2 9 13 13 13 12 Leucine rich repeat LRR_1 PF00560.28 KFO96326.1 - 2.1e-38 124.4 66.4 0.002 17.8 0.1 19.8 20 0 0 20 20 20 12 Leucine Rich Repeat LRR_7 PF13504.1 KFO96326.1 - 3.3e-21 71.6 68.1 0.025 14.6 0.0 17.8 18 0 0 18 18 18 9 Leucine rich repeat LRR_6 PF13516.1 KFO96326.1 - 3.2e-11 42.0 64.1 0.1 12.7 0.0 17.4 18 2 1 19 19 19 5 Leucine Rich repeat LRR_9 PF14580.1 KFO96326.1 - 0.00013 21.6 22.2 0.14 11.6 0.5 5.5 2 2 4 6 6 6 4 Leucine-rich repeat Dynactin_p22 PF07426.6 KFO96326.1 - 0.55 9.5 5.6 1.7 7.9 0.2 3.8 3 1 1 4 4 4 0 Dynactin subunit p22 RRM_5 PF13893.1 KFO96327.1 - 0.036 13.9 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPCR_chapero_1 PF11904.3 KFO96328.1 - 2e-79 266.9 0.1 2.7e-79 266.4 0.1 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank PF00023.25 KFO96328.1 - 1.2e-11 43.7 0.4 1.1e-07 31.2 0.5 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFO96328.1 - 1.4e-10 41.3 0.1 2.5e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO96328.1 - 8.9e-08 32.4 0.1 2e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO96328.1 - 9.6e-08 32.0 0.3 2.7e-07 30.5 0.2 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO96328.1 - 7.7e-07 28.7 0.1 0.00087 19.3 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat 7tm_1 PF00001.16 KFO96329.1 - 1.8e-25 89.5 13.1 2.2e-25 89.2 9.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFO96329.1 - 5.4e-07 28.9 2.6 7.2e-07 28.5 1.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.4 KFO96329.1 - 0.00033 20.0 0.1 0.00033 20.0 0.1 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc zf-RanBP PF00641.13 KFO96330.1 - 1.4e-09 36.8 19.6 1.2e-06 27.4 6.6 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KFO96330.1 - 0.9 9.4 9.8 9.2 6.1 1.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon GCC2_GCC3 PF07699.8 KFO96330.1 - 3.8 7.1 8.0 1.7 8.2 0.1 3.3 2 1 0 2 2 2 0 GCC2 and GCC3 DUF605 PF04652.11 KFO96330.1 - 7.5 5.8 35.2 9.5 5.4 24.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF936 PF06075.7 KFO96330.1 - 8.2 5.2 42.6 11 4.8 29.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) I-set PF07679.11 KFO96331.1 - 3.6e-35 119.6 0.1 3.2e-12 46.1 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96331.1 - 4.9e-28 97.0 0.3 4.3e-11 42.7 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFO96331.1 - 7.1e-28 96.8 2.1 1.8e-11 44.3 0.0 3.9 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 KFO96331.1 - 6.9e-19 67.7 2.1 3.3e-08 33.5 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFO96331.1 - 5.3e-14 52.0 3.0 0.00034 20.4 0.1 4.4 2 2 1 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO96331.1 - 2.7e-05 24.0 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFO96331.1 - 0.0099 14.1 1.0 0.034 12.4 0.1 2.1 2 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 KFO96331.1 - 0.011 15.5 0.0 6.4 6.5 0.0 2.8 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Ank PF00023.25 KFO96332.1 - 2.4e-60 197.5 22.8 3.8e-09 35.9 0.0 10.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_2 PF12796.2 KFO96332.1 - 1.8e-57 191.6 6.9 3.9e-18 65.5 0.1 5.5 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.12 KFO96332.1 - 2.6e-57 193.8 0.0 3.9e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO96332.1 - 3.3e-48 164.0 0.0 7.4e-48 162.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Ank_4 PF13637.1 KFO96332.1 - 2.5e-47 158.4 10.7 4.2e-11 43.0 0.1 7.0 4 2 4 8 8 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO96332.1 - 1.2e-44 145.8 16.8 7.9e-07 28.7 0.2 10.5 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 KFO96332.1 - 9.4e-38 127.3 15.6 6.9e-07 29.3 0.4 9.2 3 2 6 9 9 9 8 Ankyrin repeats (many copies) RIO1 PF01163.17 KFO96332.1 - 0.028 13.7 1.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KFO96332.1 - 0.046 13.4 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFO96332.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoU_methylas_C PF12105.3 KFO96332.1 - 0.069 12.7 0.0 1.1 8.8 0.0 2.7 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal DUF4160 PF13711.1 KFO96332.1 - 0.12 12.2 0.4 0.47 10.3 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) DUF4590 PF15257.1 KFO96333.1 - 6.3e-60 200.0 0.4 1.1e-59 199.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) ADH_zinc_N PF00107.21 KFO96334.1 - 2.6e-23 81.9 1.0 1.1e-22 79.9 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFO96334.1 - 5.7e-15 56.3 0.0 2.3e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFO96334.1 - 1.6e-13 50.3 2.0 7.2e-13 48.2 0.1 2.5 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 KFO96334.1 - 0.018 14.8 0.9 0.018 14.8 0.6 2.3 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TYW3 PF02676.9 KFO96335.1 - 6.3e-31 107.1 0.1 7.2e-31 106.9 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 Choline_transpo PF04515.7 KFO96336.1 - 4.3e-131 436.5 31.3 4.3e-131 436.5 21.7 2.8 3 0 0 3 3 3 2 Plasma-membrane choline transporter Prenyltrans PF00432.16 KFO96337.1 - 5.3e-73 240.2 9.7 5.4e-16 57.8 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFO96337.1 - 9.1e-31 106.5 0.0 1.8e-19 70.2 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFO96337.1 - 1e-11 44.7 0.0 1.4e-09 37.9 0.0 3.2 4 1 0 4 4 4 1 Prenyltransferase-like BAG PF02179.11 KFO96337.1 - 0.018 15.1 0.1 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 BAG domain MutS_V PF00488.16 KFO96338.1 - 6.5e-86 287.5 0.1 1.1e-85 286.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFO96338.1 - 2.8e-34 118.6 0.8 7.9e-34 117.2 0.3 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 KFO96338.1 - 1.7e-19 70.2 0.2 4.1e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KFO96338.1 - 9.8e-16 57.7 0.0 2.4e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 KFO96338.1 - 2.2e-05 24.3 1.3 0.00031 20.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFO96338.1 - 0.0069 15.8 0.0 0.46 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFO96338.1 - 0.0078 16.3 0.5 0.062 13.4 0.0 2.8 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 KFO96338.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KFO96338.1 - 0.052 14.3 0.0 0.16 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KFO96338.1 - 0.073 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFO96338.1 - 0.077 12.6 0.1 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 KFO96338.1 - 0.13 11.9 3.2 0.37 10.4 0.5 2.7 2 1 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 KFO96338.1 - 0.22 11.8 4.7 0.053 13.8 0.4 2.1 2 2 0 2 2 2 0 AAA domain NYD-SP12_N PF15015.1 KFO96339.1 - 9.6e-219 727.3 1.9 1.2e-218 727.0 1.3 1.0 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_11 PF13414.1 KFO96339.1 - 0.00017 21.1 2.7 0.052 13.2 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFO96339.1 - 0.00029 20.3 2.0 0.31 10.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFO96339.1 - 0.008 16.0 5.4 3.3 7.8 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO96339.1 - 0.078 12.9 2.8 6.9 6.6 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFO96339.1 - 0.1 12.4 4.9 4 7.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFO96339.1 - 0.1 13.2 5.5 4.9 7.9 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96339.1 - 0.36 11.6 5.1 5.2 7.9 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat RhoGEF PF00621.15 KFO96341.1 - 5.7e-45 153.3 0.9 1.1e-44 152.4 0.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PTCB-BRCT PF12738.2 KFO96341.1 - 9.3e-24 83.0 4.5 1.2e-17 63.5 0.1 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 KFO96341.1 - 5.5e-16 58.4 1.4 7.9e-07 29.1 0.0 3.1 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DUF3810 PF12725.2 KFO96341.1 - 0.27 10.0 0.1 0.63 8.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Abhydrolase_3 PF07859.8 KFO96342.1 - 1.4e-52 178.3 0.1 2.6e-38 131.7 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFO96342.1 - 5.1e-07 28.6 0.0 7.5e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KFO96342.1 - 1.8e-06 26.9 0.0 0.00037 19.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KFO96342.1 - 3.8e-05 23.4 0.0 5.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFO96342.1 - 0.00011 21.5 0.0 0.00052 19.2 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family PuR_N PF09182.5 KFO96342.1 - 0.025 14.1 0.1 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Chlorophyllase2 PF12740.2 KFO96342.1 - 0.04 12.7 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.7 KFO96342.1 - 0.043 12.2 0.0 0.069 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TNF PF00229.13 KFO96343.1 - 3.6e-30 104.1 0.4 5.7e-30 103.4 0.3 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family fn3 PF00041.16 KFO96344.1 - 2.3e-100 328.8 2.3 3.4e-11 43.1 0.0 9.9 9 1 0 9 9 9 9 Fibronectin type III domain Interfer-bind PF09294.5 KFO96344.1 - 7.8e-12 45.1 8.2 1.4 9.0 0.0 8.1 8 0 0 8 8 8 4 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.1 KFO96344.1 - 7.6e-06 25.7 0.0 3.8 7.3 0.0 5.7 7 0 0 7 7 7 2 SusE outer membrane protein Y_Y_Y PF07495.8 KFO96344.1 - 0.017 14.8 0.4 5.3 6.8 0.0 4.9 8 0 0 8 8 8 0 Y_Y_Y domain PX PF00787.19 KFO96345.1 - 2.7e-20 72.2 3.5 8.7e-20 70.6 2.5 1.9 1 0 0 1 1 1 1 PX domain PLDc PF00614.17 KFO96345.1 - 1.1e-16 60.0 2.3 1.1e-08 34.5 0.1 3.5 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFO96345.1 - 1e-12 47.9 0.4 9.8e-09 35.0 0.1 2.9 2 1 0 2 2 2 2 PLD-like domain PH PF00169.24 KFO96345.1 - 1.2e-06 28.6 0.0 3.7e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF3785 PF12653.2 KFO96345.1 - 0.011 15.6 0.2 0.027 14.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Intein_splicing PF14890.1 KFO96345.1 - 0.047 12.5 0.1 0.099 11.5 0.0 1.5 1 0 0 1 1 1 0 Intein splicing domain Argos PF11581.3 KFO96345.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos Pkinase PF00069.20 KFO96346.1 - 5.3e-67 225.6 0.0 5.3e-67 225.6 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain CNH PF00780.17 KFO96346.1 - 1.4e-59 201.7 0.0 2.2e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 KFO96346.1 - 1.1e-48 165.6 0.0 2.1e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO96346.1 - 1.6e-05 24.0 0.0 4.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Sugar_tr PF00083.19 KFO96347.1 - 1.6e-153 511.4 24.3 1.8e-153 511.3 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFO96347.1 - 1.5e-21 76.4 35.7 1.5e-18 66.6 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFO96347.1 - 1.3e-10 40.3 27.9 5.7e-08 31.5 4.9 3.3 1 1 1 3 3 3 2 MFS/sugar transport protein TM231 PF10149.4 KFO96347.1 - 0.036 13.0 0.5 0.08 11.9 0.4 1.5 1 0 0 1 1 1 0 Transmembrane protein 231 eIF-5a PF01287.15 KFO96348.1 - 5.6e-26 90.2 0.1 7.7e-26 89.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KFO96348.1 - 0.0015 18.1 0.2 0.0027 17.3 0.2 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KFO96348.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Ribosomal_L22e PF01776.12 KFO96349.1 - 2.3e-48 162.8 2.9 2.8e-48 162.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AA_permease_2 PF13520.1 KFO96350.1 - 3.8e-47 160.7 55.2 1.7e-45 155.3 26.2 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KFO96350.1 - 9.6e-39 133.0 39.1 9.6e-39 133.0 27.1 2.4 2 1 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.1 KFO96350.1 - 2.3e-20 72.1 9.8 2.3e-20 72.1 6.8 4.8 5 0 0 5 5 5 1 C-terminus of AA_permease PMP22_Claudin PF00822.15 KFO96351.1 - 1.1e-19 70.6 11.1 1.6e-19 70.2 7.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO96351.1 - 1.9e-08 34.2 6.5 1.9e-08 34.2 4.5 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KFO96351.1 - 1.7 7.8 5.3 0.95 8.6 0.4 2.2 2 0 0 2 2 2 0 Clc-like DUF4233 PF14017.1 KFO96351.1 - 4 7.4 8.3 0.22 11.4 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) c-SKI_SMAD_bind PF08782.5 KFO96352.1 - 4.6e-44 148.4 3.2 4.6e-44 148.4 2.2 2.3 2 0 0 2 2 2 1 c-SKI Smad4 binding domain Ski_Sno PF02437.12 KFO96352.1 - 8.7e-44 147.7 1.0 2.4e-43 146.3 0.7 1.7 1 0 0 1 1 1 1 SKI/SNO/DAC family DUF489 PF04356.7 KFO96352.1 - 0.48 9.9 9.6 0.33 10.5 5.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Pkinase PF00069.20 KFO96353.1 - 2.2e-64 217.0 0.0 3e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96353.1 - 2.2e-34 118.6 0.0 3.3e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFO96353.1 - 8.1e-15 54.2 7.5 1.6e-14 53.3 5.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PB1 PF00564.19 KFO96353.1 - 8.9e-11 41.3 0.1 2.4e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Pkinase_C PF00433.19 KFO96353.1 - 8.1e-07 29.4 1.1 1.8e-06 28.3 0.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFO96353.1 - 3.2e-06 26.3 0.0 4.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO96353.1 - 0.01 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO96353.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_3 PF07649.7 KFO96353.1 - 0.1 12.6 1.6 0.34 11.0 1.1 1.8 1 0 0 1 1 1 0 C1-like domain PHD PF00628.24 KFO96353.1 - 0.91 9.2 4.9 1.9 8.2 3.4 1.5 1 0 0 1 1 1 0 PHD-finger Ribosomal_S26e PF01283.14 KFO96354.1 - 0.99 9.6 4.0 0.54 10.5 0.2 2.4 3 0 0 3 3 3 0 Ribosomal protein S26e Sec62 PF03839.11 KFO96355.1 - 4.8e-92 307.4 6.3 4.8e-92 307.4 4.3 2.4 2 1 1 3 3 3 1 Translocation protein Sec62 Ycf1 PF05758.7 KFO96355.1 - 0.0028 15.4 0.7 0.0028 15.4 0.5 2.1 2 0 0 2 2 2 2 Ycf1 DEP PF00610.16 KFO96355.1 - 0.044 13.5 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) BUD22 PF09073.5 KFO96355.1 - 0.085 11.9 51.2 0.094 11.7 9.9 2.1 2 0 0 2 2 2 0 BUD22 SpoIIIAH PF12685.2 KFO96355.1 - 0.83 9.1 19.2 0.12 11.8 0.5 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein SAM_1 PF00536.25 KFO96356.1 - 2.3e-13 50.1 0.0 4.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFO96356.1 - 6.3e-10 38.7 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 KFO96356.1 - 0.14 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif LRR_6 PF13516.1 KFO96357.1 - 2.7e-20 70.0 50.3 0.033 14.2 0.0 14.4 14 1 1 15 15 15 8 Leucine Rich repeat LRR_4 PF12799.2 KFO96357.1 - 3.5e-16 58.4 49.1 0.0021 17.6 2.7 10.0 1 1 11 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO96357.1 - 2.6e-15 55.9 38.3 0.0002 21.0 1.4 8.8 3 2 6 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 KFO96357.1 - 8.6e-14 49.4 36.1 1.7 8.9 0.7 13.6 11 2 2 13 13 13 5 Leucine Rich Repeat LRR_7 PF13504.1 KFO96357.1 - 3.4e-13 47.4 39.4 9.3 6.9 0.0 14.6 15 0 0 15 15 15 4 Leucine rich repeat PYRIN PF02758.11 KFO96357.1 - 0.0059 16.2 0.2 3.5 7.3 0.0 2.9 2 0 0 2 2 2 2 PAAD/DAPIN/Pyrin domain LRR_4 PF12799.2 KFO96358.1 - 2.3e-53 177.0 71.0 6.4e-10 38.4 0.1 11.9 4 2 8 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO96358.1 - 2.3e-40 136.1 62.3 9.3e-08 31.7 2.0 8.9 2 2 7 10 10 10 10 Leucine rich repeat LRR_1 PF00560.28 KFO96358.1 - 6.5e-27 89.4 65.5 0.11 12.6 0.4 18.1 18 1 0 18 18 18 12 Leucine Rich Repeat LRR_7 PF13504.1 KFO96358.1 - 1.8e-12 45.2 56.1 0.91 9.9 0.2 16.3 17 1 0 17 17 17 5 Leucine rich repeat LRR_6 PF13516.1 KFO96358.1 - 0.00019 21.1 58.9 4.4 7.6 1.5 15.3 14 4 3 17 17 17 3 Leucine Rich repeat Viral_DNA_bi PF02236.12 KFO96358.1 - 0.039 14.1 2.8 4.6 7.4 0.1 4.1 5 0 0 5 5 5 0 Viral DNA-binding protein, all alpha domain LRR_9 PF14580.1 KFO96358.1 - 0.074 12.6 23.6 0.081 12.4 1.0 4.4 2 2 4 6 6 6 0 Leucine-rich repeat LRR_6 PF13516.1 KFO96359.1 - 3.6e-24 82.0 13.4 0.00079 19.2 0.0 8.1 7 0 0 7 7 7 7 Leucine Rich repeat LRR_4 PF12799.2 KFO96359.1 - 4.8e-10 38.8 1.2 0.00047 19.7 0.0 5.1 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96359.1 - 1.7e-07 30.2 1.9 1.3 9.3 0.0 7.5 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_7 PF13504.1 KFO96359.1 - 0.00017 21.2 5.5 3.8 8.1 0.0 6.7 7 0 0 7 7 7 1 Leucine rich repeat LRR_8 PF13855.1 KFO96359.1 - 0.00076 19.1 11.6 0.18 11.5 0.4 5.3 2 2 2 5 5 5 3 Leucine rich repeat DUF2518 PF10726.4 KFO96359.1 - 0.088 12.3 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of function (DUF2518) zf-H2C2_2 PF13465.1 KFO96360.1 - 5e-59 193.8 43.1 3.1e-09 36.6 0.1 9.6 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFO96360.1 - 4.5e-37 124.1 53.4 5.1e-06 26.5 0.3 8.6 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96360.1 - 6.9e-28 94.8 45.8 0.00047 20.2 1.6 8.6 8 0 0 8 8 8 8 C2H2-type zinc finger BTB PF00651.26 KFO96360.1 - 3.2e-24 85.0 0.2 7.7e-24 83.8 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_jaz PF12171.3 KFO96360.1 - 5.4e-14 51.8 31.2 0.026 14.6 0.0 8.4 9 0 0 9 9 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO96360.1 - 3.7e-12 45.7 36.5 0.062 13.2 0.0 8.8 8 1 0 8 8 8 6 C2H2-type zinc finger zf-met PF12874.2 KFO96360.1 - 1.1e-06 28.6 52.1 0.002 18.2 0.3 8.7 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFO96360.1 - 0.00031 20.7 30.4 0.062 13.4 0.4 5.6 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KFO96360.1 - 0.0074 16.0 0.4 0.0074 16.0 0.2 7.5 3 2 5 8 8 8 2 BED zinc finger Zn-ribbon_8 PF09723.5 KFO96360.1 - 0.016 15.1 26.2 8.7 6.3 0.0 7.6 5 1 1 6 6 6 0 Zinc ribbon domain XPA_N PF01286.13 KFO96360.1 - 0.25 11.0 25.1 23 4.7 0.0 7.7 8 0 0 8 8 8 0 XPA protein N-terminal DUF1610 PF07754.6 KFO96360.1 - 0.67 10.1 0.0 0.67 10.1 0.0 6.3 7 0 0 7 7 6 0 Domain of unknown function (DUF1610) C1_4 PF07975.7 KFO96360.1 - 0.85 9.6 29.9 2.7 8.0 4.8 6.0 1 1 7 8 8 8 0 TFIIH C1-like domain zf-C2H2_2 PF12756.2 KFO96360.1 - 1.2 9.3 32.7 0.66 10.1 0.1 6.5 1 1 6 7 7 6 0 C2H2 type zinc-finger (2 copies) RRN7 PF11781.3 KFO96360.1 - 9.2 5.8 17.5 51 3.4 0.2 6.5 7 0 0 7 7 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 NfI_DNAbd_pre-N PF10524.4 KFO96361.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Sarcoglycan_1 PF04790.8 KFO96362.1 - 9e-104 346.3 0.0 1e-103 346.1 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 KFO96362.1 - 0.00088 18.9 0.0 0.0071 15.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) Ribosomal_L22 PF00237.14 KFO96363.1 - 1e-21 76.8 0.5 1.5e-21 76.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e WD40 PF00400.27 KFO96364.1 - 5.4e-53 175.0 29.9 4.2e-10 39.1 0.0 12.9 13 0 0 13 13 13 11 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KFO96364.1 - 0.00077 18.9 0.0 10 5.7 0.0 5.2 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KFO96364.1 - 0.0012 17.0 1.0 0.047 11.8 0.2 3.1 4 0 0 4 4 4 1 Nucleoporin Nup120/160 CAF1 PF04857.15 KFO96365.1 - 2.9e-71 239.8 0.2 4.2e-71 239.3 0.1 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease FA_hydroxylase PF04116.8 KFO96366.1 - 3.4e-14 53.2 18.7 3.4e-14 53.2 13.0 2.7 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily TRIQK PF15168.1 KFO96366.1 - 0.27 11.1 2.2 11 6.0 0.1 2.7 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family La PF05383.12 KFO96367.1 - 7.2e-24 83.3 0.3 2.2e-23 81.7 0.1 2.0 2 0 0 2 2 2 1 La domain HLH PF00010.21 KFO96368.1 - 9.8e-17 60.3 0.1 1.8e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NicO PF03824.11 KFO96368.1 - 2 7.6 5.6 2.6 7.3 3.9 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein SAP30_Sin3_bdg PF13867.1 KFO96369.1 - 1.7e-25 88.6 0.2 4.1e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.1 KFO96369.1 - 7.9e-10 38.2 0.5 1.8e-09 37.1 0.3 1.6 1 0 0 1 1 1 1 SAP30 zinc-finger Glycos_transf_2 PF00535.21 KFO96370.1 - 9.4e-30 103.5 0.0 1.9e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFO96370.1 - 2.5e-27 95.3 0.9 3.6e-27 94.8 0.6 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 KFO96370.1 - 2.6e-08 33.1 0.1 6.2e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFO96370.1 - 1.1e-07 31.2 0.0 1.7e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFO96370.1 - 0.0039 17.5 0.0 0.51 10.7 0.0 2.6 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like rve_2 PF13333.1 KFO96370.1 - 0.014 15.4 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain I-set PF07679.11 KFO96371.1 - 6.6e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 KFO96371.1 - 9.4e-08 31.9 0.1 5.1e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFO96371.1 - 5.3e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO96371.1 - 0.00095 19.6 0.0 0.0047 17.3 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO96371.1 - 0.0021 18.1 0.0 0.0062 16.6 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain DUF4446 PF14584.1 KFO96371.1 - 0.079 12.7 0.4 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF719 PF05334.8 KFO96372.1 - 1.7e-66 223.7 1.6 1.7e-66 223.7 1.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF719) LON PF02190.11 KFO96373.1 - 8e-25 87.7 0.0 1.1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KFO96373.1 - 1.1e-08 34.9 14.7 1.1e-08 34.8 8.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO96373.1 - 3.5e-08 32.9 10.1 9.5e-08 31.5 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO96373.1 - 1.6e-07 30.9 16.4 1.6e-07 30.9 11.3 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFO96373.1 - 3.1e-07 29.9 13.2 3.1e-07 29.9 9.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO96373.1 - 1.6e-06 27.7 13.1 5.1e-06 26.1 9.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFO96373.1 - 3e-05 23.6 7.2 0.00023 20.7 5.0 2.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFO96373.1 - 6.7e-05 22.6 12.9 0.00029 20.6 8.9 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.10 KFO96373.1 - 0.00078 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain DUF35_N PF12172.3 KFO96373.1 - 0.013 15.4 0.3 0.013 15.4 0.2 2.6 2 0 0 2 2 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-RING_6 PF14835.1 KFO96373.1 - 0.023 14.4 8.7 0.053 13.3 6.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFO96373.1 - 0.041 13.4 12.2 0.22 11.1 8.5 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFO96373.1 - 0.13 12.3 9.9 0.41 10.7 6.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 KFO96373.1 - 0.24 10.9 10.8 0.17 11.4 5.7 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KFO96373.1 - 2.7 7.5 16.7 2.4 7.6 4.6 2.5 1 1 1 2 2 2 0 P-11 zinc finger Lig_chan PF00060.21 KFO96374.1 - 8.1e-60 200.8 0.0 1.4e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 KFO96374.1 - 1.4e-58 198.3 0.1 2e-58 197.8 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 KFO96374.1 - 3.4e-26 91.0 0.6 1.2e-25 89.2 0.1 2.2 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFO96374.1 - 6.8e-26 90.8 0.0 1.3e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF659 PF04937.10 KFO96374.1 - 0.07 12.6 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) 7tm_1 PF00001.16 KFO96375.1 - 9.1e-52 175.7 20.1 1.3e-51 175.2 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO96375.1 - 2.8e-10 39.7 19.5 5.5e-10 38.8 13.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2852 PF11014.3 KFO96375.1 - 0.24 11.3 0.2 0.24 11.3 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2852) 7TM_GPCR_Srx PF10328.4 KFO96375.1 - 0.27 10.3 25.1 2.3 7.2 17.0 2.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Sigma_reg_N PF13800.1 KFO96375.1 - 5.4 7.1 16.6 0.46 10.5 0.2 4.7 3 1 2 5 5 5 0 Sigma factor regulator N-terminal Neur_chan_LBD PF02931.18 KFO96376.1 - 3.9e-56 189.6 0.0 5e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFO96376.1 - 3.8e-46 157.9 1.8 5e-37 128.0 1.3 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region HMA PF00403.21 KFO96377.1 - 1.4e-09 37.9 0.1 1.6e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain SPARC_Ca_bdg PF10591.4 KFO96378.1 - 1.4e-42 144.3 0.6 2.8e-42 143.3 0.4 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.16 KFO96378.1 - 3.3e-12 46.2 4.6 3.3e-12 46.2 3.2 2.9 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFO96378.1 - 5.4e-11 42.2 2.1 5.4e-11 42.2 1.5 2.3 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 KFO96378.1 - 2.1e-10 40.2 10.5 2.1e-10 40.2 7.3 2.0 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain EF-hand_1 PF00036.27 KFO96378.1 - 0.086 12.1 0.3 0.63 9.4 0.0 2.4 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 KFO96378.1 - 0.11 12.3 0.0 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KFO96378.1 - 0.52 10.4 3.1 1.3 9.2 0.1 2.8 2 2 1 3 3 2 0 EF-hand domain pair Cadherin PF00028.12 KFO96379.1 - 0 1586.6 46.3 4.9e-22 77.9 0.0 33.7 34 0 0 34 34 34 33 Cadherin domain Laminin_G_2 PF02210.19 KFO96379.1 - 1.4e-16 60.7 0.2 4.3e-16 59.1 0.1 2.0 1 0 0 1 1 1 1 Laminin G domain Cadherin_2 PF08266.7 KFO96379.1 - 8.1e-15 54.1 0.5 0.84 9.2 0.0 15.1 21 0 0 21 21 21 2 Cadherin-like EGF PF00008.22 KFO96379.1 - 1.4e-13 50.4 42.6 7.9e-06 25.7 6.4 3.5 3 0 0 3 3 3 3 EGF-like domain Laminin_G_1 PF00054.18 KFO96379.1 - 1.2e-10 41.5 0.0 5.4e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Laminin G domain Laminin_G_3 PF13385.1 KFO96379.1 - 0.00015 22.0 2.7 0.00066 19.9 0.1 3.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily EGF_2 PF07974.8 KFO96379.1 - 0.56 10.4 52.6 0.015 15.4 7.9 3.9 3 0 0 3 3 3 0 EGF-like domain Aa_trans PF01490.13 KFO96380.1 - 2.7e-73 246.7 28.2 3.2e-73 246.5 19.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein E1_DerP2_DerF2 PF02221.10 KFO96381.1 - 1.7e-27 96.2 0.0 2.1e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF2443 PF10398.4 KFO96382.1 - 0.035 13.9 2.1 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) DUF4407 PF14362.1 KFO96382.1 - 0.067 12.1 8.6 0.081 11.8 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sigma70_ner PF04546.8 KFO96382.1 - 0.18 11.3 11.8 0.21 11.1 8.2 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region MRP-L47 PF06984.8 KFO96382.1 - 0.28 11.0 6.7 0.39 10.6 4.5 1.4 1 1 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2894 PF11445.3 KFO96382.1 - 0.29 11.3 7.6 0.37 11.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Transposase_22 PF02994.9 KFO96382.1 - 0.33 9.3 13.5 0.37 9.2 9.4 1.1 1 0 0 1 1 1 0 L1 transposable element TFIIE_alpha PF02002.12 KFO96382.1 - 0.5 9.8 5.2 0.15 11.5 1.4 1.7 2 0 0 2 2 2 0 TFIIE alpha subunit DUF1664 PF07889.7 KFO96382.1 - 0.51 10.1 8.1 0.66 9.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 KFO96382.1 - 1 7.6 11.8 1 7.6 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 KFO96382.1 - 1 9.6 6.2 1.2 9.3 0.6 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Glyco_transf_15 PF01793.11 KFO96382.1 - 1.1 8.1 9.0 1.3 7.8 6.2 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Exonuc_VII_L PF02601.10 KFO96382.1 - 1.4 8.0 15.4 1.7 7.7 10.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tht1 PF04163.7 KFO96382.1 - 2.2 6.5 6.7 3.2 6.0 4.7 1.3 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein ALMT PF11744.3 KFO96382.1 - 2.2 6.8 6.3 2.5 6.6 4.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF775 PF05603.7 KFO96382.1 - 2.4 7.6 6.4 2.9 7.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Syntaxin-6_N PF09177.6 KFO96382.1 - 2.8 8.4 10.9 1.3 9.5 4.4 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ARD PF03079.9 KFO96382.1 - 3.5 7.5 9.4 16 5.4 6.7 1.8 1 1 0 1 1 1 0 ARD/ARD' family APG6 PF04111.7 KFO96382.1 - 4.3 6.3 19.3 4.8 6.1 13.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 KFO96382.1 - 4.6 6.2 12.0 1.9 7.5 6.5 1.5 1 1 1 2 2 2 0 TMPIT-like protein DUF948 PF06103.6 KFO96382.1 - 6.7 6.6 6.7 31 4.5 0.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Annexin PF00191.15 KFO96383.1 - 6.7e-179 580.0 32.4 2.2e-25 88.3 0.5 8.1 8 0 0 8 8 8 8 Annexin Sigma70_ner PF04546.8 KFO96383.1 - 0.0044 16.6 0.9 0.61 9.6 0.3 2.6 2 1 0 2 2 2 2 Sigma-70, non-essential region Acetyltransf_11 PF13720.1 KFO96383.1 - 0.6 10.3 4.8 21 5.4 0.0 4.7 5 0 0 5 5 5 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GSHPx PF00255.14 KFO96384.1 - 2e-22 78.6 0.1 2.7e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Dynactin_p62 PF05502.8 KFO96385.1 - 1.1e-94 317.9 20.1 1.3e-65 222.0 0.9 2.3 1 1 1 2 2 2 2 Dynactin p62 family Elf1 PF05129.8 KFO96385.1 - 0.17 11.6 4.5 0.42 10.3 1.4 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RRM_1 PF00076.17 KFO96386.1 - 5.4e-12 45.1 0.1 8.6e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96386.1 - 1.3e-11 44.3 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96386.1 - 5.7e-11 42.0 0.3 1.1e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFO96386.1 - 7.8e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KFO96386.1 - 0.0033 17.0 1.4 0.0033 17.0 1.0 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 KFO96386.1 - 0.0038 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif FYVE PF01363.16 KFO96386.1 - 0.0069 16.2 1.1 0.0069 16.2 0.8 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.1 KFO96386.1 - 0.034 14.1 0.8 0.034 14.1 0.5 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Calsarcin PF05556.6 KFO96387.1 - 1.4e-49 168.7 0.3 1.8e-49 168.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) HSNSD PF12062.3 KFO96388.1 - 4.5e-263 872.9 0.0 7.6e-263 872.2 0.0 1.3 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 KFO96388.1 - 8.4e-47 159.6 0.0 1.3e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFO96388.1 - 0.0091 16.9 2.3 0.01 16.8 0.1 2.3 2 1 0 2 2 2 1 Sulfotransferase family Ribosomal_S11 PF00411.14 KFO96389.1 - 8.6e-41 138.5 0.2 1.1e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 MHC2-interact PF09307.5 KFO96390.1 - 7.3e-38 128.8 2.4 1.4e-37 127.9 1.7 1.4 1 0 0 1 1 1 1 CLIP, MHC2 interacting MHCassoc_trimer PF08831.5 KFO96390.1 - 2.5e-34 116.9 5.0 2.5e-34 116.9 3.5 1.8 2 0 0 2 2 2 1 Class II MHC-associated invariant chain trimerisation domain MLANA PF14991.1 KFO96390.1 - 0.067 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Sulfatase PF00884.18 KFO96392.1 - 6.7e-71 238.9 0.0 8.9e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFO96392.1 - 0.0014 18.9 0.1 0.01 16.1 0.0 2.4 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase SNF PF00209.13 KFO96393.1 - 5.7e-227 754.3 38.5 6.6e-227 754.1 26.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.12 KFO96393.1 - 3.2 7.3 9.5 0.44 10.1 1.9 2.6 3 0 0 3 3 3 0 Caveolin Caudal_act PF04731.7 KFO96394.1 - 2.3e-47 160.7 16.4 4.1e-47 159.9 11.3 1.3 1 0 0 1 1 1 1 Caudal like protein activation region Homeobox PF00046.24 KFO96394.1 - 3.9e-21 74.4 1.4 6.6e-21 73.6 0.9 1.4 1 0 0 1 1 1 1 Homeobox domain Pkinase_Tyr PF07714.12 KFO96395.1 - 7.8e-108 359.4 0.0 1.2e-107 358.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO96395.1 - 3.7e-48 163.9 0.0 4e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFO96395.1 - 4.9e-28 96.8 4.5 2.5e-10 40.0 0.0 4.7 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96395.1 - 7.2e-22 77.3 12.4 6e-11 42.3 0.1 5.6 5 2 0 5 5 5 4 Immunoglobulin domain ig PF00047.20 KFO96395.1 - 2.3e-15 56.4 13.9 9.6e-07 28.8 0.1 6.5 6 0 0 6 6 6 3 Immunoglobulin domain Ig_3 PF13927.1 KFO96395.1 - 3.7e-13 49.7 16.4 9.5e-05 22.8 0.5 5.6 6 0 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 KFO96395.1 - 1.1e-08 34.9 7.8 1e-05 25.3 0.1 5.0 4 2 0 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO96395.1 - 9.1e-07 28.7 9.8 0.081 12.8 0.1 5.1 4 1 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Herpes_gI PF01688.12 KFO96395.1 - 0.0067 15.5 0.0 0.39 9.8 0.0 2.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein I DUF3139 PF11337.3 KFO96395.1 - 0.081 13.2 1.8 0.21 11.8 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Pkinase_Tyr PF07714.12 KFO96396.1 - 3.8e-107 357.1 0.0 5.6e-107 356.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO96396.1 - 4.1e-45 153.9 0.0 4.8e-27 94.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFO96396.1 - 1.8e-32 111.0 0.0 9.2e-10 38.2 0.0 5.9 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96396.1 - 2.3e-28 98.1 6.4 9.1e-08 32.1 0.1 5.7 4 1 1 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 KFO96396.1 - 1.3e-21 76.7 18.6 5.5e-08 33.1 0.0 5.9 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.20 KFO96396.1 - 1.4e-13 50.7 12.6 1.8e-05 24.7 0.1 5.4 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 KFO96396.1 - 2.5e-11 43.4 10.0 0.0031 17.3 1.7 5.6 4 2 0 4 4 4 3 Immunoglobulin V-set domain C2-set PF05790.10 KFO96396.1 - 0.0014 18.5 1.3 2.2 8.2 0.1 3.6 4 0 0 4 4 4 2 Immunoglobulin C2-set domain APH PF01636.18 KFO96396.1 - 0.0052 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Lep_receptor_Ig PF06328.6 KFO96396.1 - 0.13 12.1 1.4 15 5.5 0.1 3.5 3 1 0 3 3 3 0 Ig-like C2-type domain HMG_box_2 PF09011.5 KFO96397.1 - 4.6e-11 42.9 0.8 1.1e-10 41.6 0.5 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 KFO96397.1 - 4.1e-10 39.7 0.7 1.1e-09 38.4 0.5 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box zf-IS66 PF13005.2 KFO96397.1 - 0.011 15.6 2.0 0.094 12.7 0.0 3.5 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Zn_Tnp_IS91 PF14319.1 KFO96397.1 - 0.058 12.9 3.0 1.4 8.4 0.1 2.9 3 0 0 3 3 3 0 Transposase zinc-binding domain 7tm_1 PF00001.16 KFO96398.1 - 2.5e-57 193.9 22.8 3.1e-57 193.6 15.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO96398.1 - 1e-11 44.5 20.1 1.4e-11 44.0 14.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO96398.1 - 0.00053 19.1 14.4 0.00053 19.1 10.0 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Cyclin_N PF00134.18 KFO96398.1 - 0.027 14.0 0.2 0.048 13.2 0.2 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Herpes_US9 PF06072.6 KFO96398.1 - 4.4 7.2 9.8 0.76 9.6 0.3 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Pkinase_Tyr PF07714.12 KFO96399.1 - 5.1e-105 350.2 0.0 7.6e-105 349.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO96399.1 - 1.7e-45 155.1 0.0 8.4e-32 110.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain I-set PF07679.11 KFO96399.1 - 8.3e-45 150.5 8.7 3.4e-14 52.4 0.0 7.5 7 0 0 7 7 7 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96399.1 - 3.7e-43 145.5 6.7 2.9e-08 33.6 0.0 6.9 6 1 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFO96399.1 - 1.9e-31 108.3 8.0 1.9e-07 31.4 0.0 7.9 6 2 0 6 6 6 5 Immunoglobulin domain V-set PF07686.12 KFO96399.1 - 2.8e-23 82.0 9.8 2.2e-06 27.5 0.1 6.7 5 2 0 5 5 5 5 Immunoglobulin V-set domain ig PF00047.20 KFO96399.1 - 5.3e-21 74.4 13.0 6.4e-05 22.9 0.1 7.8 6 2 0 6 6 6 4 Immunoglobulin domain C1-set PF07654.10 KFO96399.1 - 1.4e-05 25.0 2.4 0.047 13.6 0.0 4.9 5 0 0 5 5 5 1 Immunoglobulin C1-set domain Receptor_2B4 PF11465.3 KFO96399.1 - 3.5e-05 23.6 1.8 0.17 11.7 0.0 3.9 4 0 0 4 4 4 2 Natural killer cell receptor 2B4 Herpes_gE PF02480.11 KFO96399.1 - 7.5e-05 21.1 0.1 0.29 9.3 0.0 3.6 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 KFO96399.1 - 0.0004 20.2 8.0 0.21 11.5 0.0 4.8 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 KFO96399.1 - 0.28 10.9 4.0 2.3 7.9 0.0 3.7 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain zf-RING_2 PF13639.1 KFO96400.1 - 5e-13 48.6 11.7 8.3e-13 47.9 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFO96400.1 - 1.9e-11 43.5 0.0 3.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFO96400.1 - 4.8e-08 32.9 6.1 9.4e-08 32.0 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFO96400.1 - 1.8e-07 30.7 10.9 3.1e-07 29.9 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO96400.1 - 2.1e-07 30.5 10.2 3.4e-07 29.8 7.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFO96400.1 - 4.5e-06 26.2 8.3 7.3e-06 25.5 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO96400.1 - 7.4e-06 25.8 11.5 1.3e-05 25.1 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFO96400.1 - 0.012 15.4 5.4 0.024 14.4 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CoA_binding_3 PF13727.1 KFO96400.1 - 0.063 13.0 0.1 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 CoA-binding domain DUF2254 PF10011.4 KFO96400.1 - 0.1 11.0 0.8 0.13 10.7 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) zf-RING_UBOX PF13445.1 KFO96400.1 - 0.21 11.3 6.2 0.5 10.1 4.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger UPF0233 PF06781.7 KFO96400.1 - 0.22 11.1 1.9 2.7 7.6 0.6 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) Prok-RING_1 PF14446.1 KFO96400.1 - 1.2 8.8 11.0 0.16 11.7 2.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 KFO96400.1 - 2.7 7.7 10.5 4.5 7.0 7.3 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KFO96400.1 - 3.9 7.5 9.5 9.2 6.4 6.6 1.6 1 0 0 1 1 1 0 RING-variant domain ZZ PF00569.12 KFO96401.1 - 1.6e-12 46.7 3.5 2.9e-12 45.9 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.19 KFO96401.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 PB1 domain FlaG PF03646.10 KFO96401.1 - 7.7 6.7 10.6 5 7.3 0.2 2.7 1 1 1 2 2 2 0 FlaG protein AAA_assoc PF14363.1 KFO96402.1 - 0.5 10.4 5.2 0.22 11.5 1.0 2.0 1 1 1 2 2 2 0 Domain associated at C-terminal with AAA Glyco_transf_54 PF04666.8 KFO96403.1 - 3.4e-135 449.6 0.5 4.6e-135 449.1 0.3 1.2 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MAPEG PF01124.13 KFO96404.1 - 0.016 14.8 0.1 0.026 14.1 0.1 1.5 1 1 0 1 1 1 0 MAPEG family Calreticulin PF00262.13 KFO96405.1 - 6.3e-162 538.3 17.5 1.1e-161 537.5 12.1 1.4 1 0 0 1 1 1 1 Calreticulin family DUF1510 PF07423.6 KFO96405.1 - 0.00025 20.4 8.7 0.00083 18.7 6.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 KFO96405.1 - 0.01 14.8 2.7 0.01 14.8 1.9 3.5 2 1 1 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 KFO96405.1 - 0.03 12.0 5.0 0.043 11.5 3.4 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 KFO96405.1 - 9.1 4.1 21.1 13 3.6 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein MAPEG PF01124.13 KFO96406.1 - 1.8e-16 59.8 2.7 1.9e-16 59.8 1.3 1.4 1 1 0 1 1 1 1 MAPEG family dNK PF01712.14 KFO96407.1 - 1e-42 145.4 1.9 1.4e-42 145.0 1.3 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 KFO96407.1 - 7.4e-08 32.7 0.0 2.9e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFO96407.1 - 0.00014 21.7 0.0 0.00081 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFO96407.1 - 0.0063 15.9 0.0 0.067 12.5 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_22 PF13401.1 KFO96407.1 - 0.007 16.5 0.1 0.023 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFO96407.1 - 0.014 16.2 0.1 0.071 13.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFO96407.1 - 0.024 14.5 0.1 0.067 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain RRM_6 PF14259.1 KFO96408.1 - 6.3e-29 99.7 0.0 2e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO96408.1 - 5.6e-25 86.7 0.0 3.4e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF PF08080.7 KFO96408.1 - 8.7e-14 50.7 15.1 2.5e-13 49.2 9.8 2.4 2 1 0 2 2 2 1 RNPHF zinc finger RRM_5 PF13893.1 KFO96408.1 - 2.3e-05 24.1 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO96408.1 - 0.0072 16.1 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 KFO96408.1 - 0.14 11.8 0.1 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 RUN PF02759.14 KFO96409.1 - 6e-31 106.9 0.2 1.5e-30 105.6 0.0 1.8 2 0 0 2 2 2 1 RUN domain Macoilin PF09726.4 KFO96409.1 - 0.015 13.5 25.0 0.019 13.2 17.3 1.1 1 0 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 KFO96409.1 - 0.016 15.0 6.4 0.016 15.0 4.5 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pep_M12B_propep PF01562.14 KFO96410.1 - 5.7e-28 97.3 0.0 9.9e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_spacer1 PF05986.9 KFO96410.1 - 5.2e-25 87.5 0.0 1.1e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFO96410.1 - 2.7e-21 75.4 59.2 6e-10 39.0 5.1 6.0 6 0 0 6 6 6 4 Thrombospondin type 1 domain Reprolysin PF01421.14 KFO96410.1 - 7.2e-20 71.4 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 KFO96410.1 - 7.9e-14 52.0 0.1 7.9e-14 52.0 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFO96410.1 - 1.2e-11 45.2 0.1 2.3e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFO96410.1 - 1.1e-10 41.8 0.3 2.5e-10 40.7 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFO96410.1 - 1.1e-08 34.9 0.1 2.1e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFO96410.1 - 0.00031 20.4 0.1 0.00067 19.4 0.1 1.6 1 0 0 1 1 1 1 Matrixin PLAC PF08686.6 KFO96410.1 - 0.0024 18.1 7.2 0.0024 18.1 5.0 3.2 3 0 0 3 3 3 1 PLAC (protease and lacunin) domain Peptidase_M7 PF02031.11 KFO96410.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DEPP PF15343.1 KFO96411.1 - 0.047 13.2 7.4 0.021 14.4 2.3 2.3 2 1 0 2 2 2 0 Decidual protein induced by progesterone family DUF4578 PF15147.1 KFO96411.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4578) Exo_endo_phos PF03372.18 KFO96412.1 - 6.3e-22 78.7 0.0 8.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KFO96412.1 - 1e-15 56.9 16.4 1e-09 37.7 1.2 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO96412.1 - 3.6e-13 49.0 22.1 3.8e-10 39.3 5.6 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KFO96412.1 - 7.1e-06 25.3 22.8 0.021 14.7 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KFO96412.1 - 2.4e-05 23.7 14.0 0.47 10.8 0.1 5.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFO96412.1 - 0.0018 18.1 10.4 1.3 9.3 0.1 4.8 4 0 0 4 4 4 2 Leucine Rich repeat DUF713 PF05218.9 KFO96412.1 - 0.074 12.7 0.9 0.19 11.4 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF713) Pkinase PF00069.20 KFO96413.1 - 7.8e-67 225.1 0.0 9.9e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96413.1 - 1.3e-29 103.0 0.1 1.8e-29 102.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO96413.1 - 3.3e-06 26.3 0.2 5.5e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFO96413.1 - 0.0003 20.1 0.2 0.0006 19.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFO96413.1 - 0.00036 20.3 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFO96413.1 - 0.00085 18.3 0.1 0.0036 16.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF1651 PF07864.6 KFO96413.1 - 0.11 12.6 0.2 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) RasGEF PF00617.14 KFO96414.1 - 3.3e-50 170.4 0.1 6.1e-50 169.5 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFO96414.1 - 4.5e-13 49.2 0.1 1.4e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Pkinase PF00069.20 KFO96415.1 - 3.7e-66 222.9 0.9 6.5e-66 222.1 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96415.1 - 5.1e-26 91.3 1.5 1.5e-25 89.7 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase HMG_box PF00505.14 KFO96416.1 - 6.4e-22 77.6 1.7 6.4e-22 77.6 1.2 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO96416.1 - 9.2e-11 41.9 2.1 1.2e-10 41.6 0.3 1.8 2 0 0 2 2 2 1 HMG-box domain Thg1C PF14413.1 KFO96417.1 - 9e-54 180.3 1.0 1.5e-53 179.6 0.7 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KFO96417.1 - 6e-48 161.8 0.6 8.7e-48 161.3 0.4 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Arena_glycoprot PF00798.13 KFO96417.1 - 0.062 11.7 0.2 0.24 9.7 0.0 1.9 2 0 0 2 2 2 0 Arenavirus glycoprotein LSM PF01423.17 KFO96418.1 - 8.4e-12 44.4 0.5 4.6e-10 38.9 0.4 2.3 1 1 0 1 1 1 1 LSM domain DUF1115 PF06544.7 KFO96419.1 - 0.39 10.4 3.3 0.42 10.2 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) CAF-1_p150 PF11600.3 KFO96419.1 - 6.7 6.0 20.6 8.5 5.6 14.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4355 PF14265.1 KFO96419.1 - 7.9 6.4 12.2 9.6 6.1 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Vitellogenin_N PF01347.17 KFO96420.1 - 4.7e-59 200.1 9.0 6.3e-59 199.7 6.3 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region Ribosomal_S5_C PF03719.10 KFO96420.1 - 0.025 13.8 0.1 5.1 6.4 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain HEAT_2 PF13646.1 KFO96420.1 - 0.036 14.3 0.9 2.3 8.5 0.2 2.9 1 1 2 3 3 3 0 HEAT repeats SH2 PF00017.19 KFO96421.1 - 2.2e-20 72.1 0.2 4.1e-20 71.3 0.2 1.4 1 0 0 1 1 1 1 SH2 domain PH PF00169.24 KFO96421.1 - 5.4e-16 58.6 1.7 5.5e-16 58.6 0.4 1.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFO96421.1 - 3.4e-05 24.0 0.6 0.00012 22.3 0.3 2.0 2 1 1 3 3 3 1 Pleckstrin homology domain MAPKK1_Int PF08923.5 KFO96422.1 - 6.6e-50 167.7 0.0 7.3e-50 167.5 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DnaJ PF00226.26 KFO96423.1 - 3.4e-27 93.9 0.9 6.7e-27 93.0 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KFO96423.1 - 2.4e-24 85.6 0.8 4.3e-24 84.8 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Histone PF00125.19 KFO96424.1 - 3.5e-22 78.3 0.1 4.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFO96424.1 - 0.0074 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sel1 PF08238.7 KFO96425.1 - 3.3e-11 43.4 2.8 8.3e-10 38.9 1.1 2.5 2 0 0 2 2 2 1 Sel1 repeat Fe_hyd_lg_C PF02906.9 KFO96425.1 - 0.035 13.3 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Endomucin PF07010.7 KFO96426.1 - 2.3e-18 66.4 0.2 2.7e-18 66.2 0.2 1.0 1 0 0 1 1 1 1 Endomucin DUF1628 PF07790.6 KFO96426.1 - 0.016 15.9 0.0 0.018 15.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) gpUL132 PF11359.3 KFO96426.1 - 0.11 11.7 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4234 PF14018.1 KFO96426.1 - 0.16 11.7 2.5 0.19 11.5 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Metallophos PF00149.23 KFO96427.1 - 5.3e-41 140.2 0.5 8.3e-41 139.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zip PF02535.17 KFO96428.1 - 3.8e-68 229.8 3.9 4.5e-68 229.5 2.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter EpsG PF14897.1 KFO96428.1 - 0.004 16.1 2.5 0.004 16.1 1.8 1.8 2 0 0 2 2 2 1 EpsG family DUF3480 PF11979.3 KFO96429.1 - 7.8e-38 129.9 0.1 8.5e-38 129.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) AAA PF00004.24 KFO96430.1 - 3.3e-15 56.4 0.0 8.6e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 KFO96430.1 - 4.2e-15 55.2 0.4 4.2e-15 55.2 0.3 2.3 2 0 0 2 2 2 1 CDC6, C terminal BAH PF01426.13 KFO96430.1 - 7.8e-11 41.7 0.1 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.1 KFO96430.1 - 1.6e-10 41.2 0.0 1.4e-09 38.1 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFO96430.1 - 5.4e-10 39.5 0.0 1.7e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KFO96430.1 - 5.2e-05 22.3 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KFO96430.1 - 0.0013 18.4 0.3 0.0053 16.4 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KFO96430.1 - 0.018 14.7 0.1 0.064 12.9 0.1 2.0 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 KFO96430.1 - 0.03 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRP38 PF03371.10 KFO96431.1 - 6.1e-68 227.8 1.2 7.6e-68 227.4 0.9 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.2 KFO96431.1 - 0.00014 22.3 49.7 0.00014 22.3 34.4 2.2 1 1 1 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PAP_assoc PF03828.14 KFO96432.1 - 4.3e-31 106.6 0.8 4.5e-16 58.5 0.1 2.9 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.18 KFO96432.1 - 2.1e-12 46.3 22.1 3.3e-05 23.5 0.8 3.8 3 0 0 3 3 3 3 Zinc knuckle NTP_transf_2 PF01909.18 KFO96432.1 - 2e-10 40.8 0.0 1.2e-06 28.6 0.0 2.8 2 0 0 2 2 2 2 Nucleotidyltransferase domain zf-CCHC_4 PF14392.1 KFO96432.1 - 1.5e-05 24.5 18.1 0.058 13.0 0.6 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 KFO96432.1 - 1.6e-05 24.2 21.4 0.0066 15.9 0.7 4.7 4 0 0 4 4 4 3 Zinc knuckle Ubiq_cyt_C_chap PF03981.7 KFO96432.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone GSHPx PF00255.14 KFO96433.1 - 1.7e-36 123.8 0.0 2.3e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KFO96433.1 - 0.00012 21.8 0.0 0.00057 19.5 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.9 KFO96433.1 - 0.00034 20.2 0.0 0.068 12.7 0.0 2.3 2 0 0 2 2 2 2 SCO1/SenC CcoS PF03597.10 KFO96433.1 - 0.95 8.9 2.7 1.5 8.3 1.9 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Shisa PF13908.1 KFO96434.1 - 0.00092 19.4 6.9 0.00092 19.4 4.8 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator EpsG PF14897.1 KFO96434.1 - 0.019 13.9 0.0 0.02 13.8 0.0 1.0 1 0 0 1 1 1 0 EpsG family Adeno_E3_CR2 PF02439.10 KFO96434.1 - 0.025 14.1 1.5 0.046 13.2 1.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PDR_assoc PF08370.6 KFO96434.1 - 0.052 13.0 4.7 0.082 12.4 3.3 1.3 1 1 0 1 1 1 0 Plant PDR ABC transporter associated Metallothio_Cad PF07846.6 KFO96434.1 - 0.079 12.8 2.7 0.17 11.7 1.9 1.5 1 0 0 1 1 1 0 Metallothionein family DUF2668 PF10873.3 KFO96434.1 - 0.21 11.7 2.7 0.26 11.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) VSP PF03302.8 KFO96434.1 - 0.24 9.9 2.8 0.39 9.2 2.0 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Sel1 PF08238.7 KFO96435.1 - 6.5e-18 64.7 0.2 1.3e-05 25.6 0.0 4.5 4 0 0 4 4 4 4 Sel1 repeat DUF4315 PF14193.1 KFO96435.1 - 0.022 14.6 2.8 0.048 13.5 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) DUF1771 PF08590.5 KFO96435.1 - 0.19 11.7 3.1 0.58 10.2 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) LRR_6 PF13516.1 KFO96436.1 - 0.00036 20.2 0.5 0.7 10.1 0.1 4.0 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.2 KFO96436.1 - 0.001 18.6 6.4 0.0064 16.0 0.9 3.9 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) His_kinase PF06580.8 KFO96436.1 - 0.0091 15.8 0.5 0.033 14.1 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase DNA_alkylation PF08713.6 KFO96436.1 - 0.016 14.7 1.7 4.8 6.6 0.1 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme LRR_8 PF13855.1 KFO96436.1 - 0.028 14.1 7.0 0.054 13.2 0.9 3.8 2 1 1 3 3 3 0 Leucine rich repeat RIX1 PF08167.7 KFO96436.1 - 0.041 13.5 8.3 0.27 10.8 0.1 3.7 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis LRR_1 PF00560.28 KFO96436.1 - 0.86 9.8 5.0 13 6.3 0.0 4.6 3 1 1 4 4 4 0 Leucine Rich Repeat ECH PF00378.15 KFO96437.1 - 6.3e-53 179.4 0.6 7e-53 179.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFO96437.1 - 0.13 12.0 0.2 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 SCP2 PF02036.12 KFO96438.1 - 2.1e-29 101.8 0.7 4.5e-29 100.7 0.5 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Thiolase_C PF02803.13 KFO96438.1 - 5.5e-11 41.9 1.5 8.4e-10 38.1 0.1 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 KFO96438.1 - 1.2e-09 37.5 0.0 5.3e-09 35.4 0.0 2.0 3 0 0 3 3 3 1 Thiolase, N-terminal domain Alkyl_sulf_C PF14864.1 KFO96438.1 - 8.6e-07 28.9 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ketoacyl-synt PF00109.21 KFO96438.1 - 0.00068 19.1 1.9 0.0028 17.1 0.7 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KFO96438.1 - 0.0013 18.3 1.9 0.0082 15.7 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 KFO96438.1 - 0.0048 16.7 0.0 0.056 13.3 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 KFO96438.1 - 0.013 13.9 0.1 0.22 9.9 0.0 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) LRRNT PF01462.13 KFO96439.1 - 7.2e-06 25.3 1.9 1.3e-05 24.5 1.3 1.4 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain SDF PF00375.13 KFO96440.1 - 3.4e-128 427.7 28.4 3.9e-128 427.5 19.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family FeoB_C PF07664.7 KFO96440.1 - 0.76 9.2 7.7 5.1 6.6 0.5 4.5 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus DUF866 PF05907.8 KFO96441.1 - 1e-57 194.1 0.0 1.3e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Mago_nashi PF02792.9 KFO96442.1 - 2.8e-82 273.5 0.4 3.1e-82 273.3 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 KFO96442.1 - 0.14 11.9 0.1 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Ldl_recept_a PF00057.13 KFO96443.1 - 4.5e-76 250.4 142.6 1.2e-13 50.6 7.1 8.0 8 0 0 8 8 7 7 Low-density lipoprotein receptor domain class A FXa_inhibition PF14670.1 KFO96443.1 - 3.5e-13 49.4 24.6 3.6e-11 42.9 5.4 6.2 7 0 0 7 7 3 2 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.12 KFO96443.1 - 1.4e-12 47.7 0.0 2.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Low-density lipoprotein receptor repeat class B cEGF PF12662.2 KFO96443.1 - 3.5e-07 29.7 18.8 7.1e-07 28.7 1.0 5.1 3 0 0 3 3 2 2 Complement Clr-like EGF-like EGF_CA PF07645.10 KFO96443.1 - 2.8e-06 27.2 11.3 2.8e-06 27.2 7.8 10.1 5 2 3 8 8 4 2 Calcium-binding EGF domain EGF PF00008.22 KFO96443.1 - 3.8e-05 23.5 21.5 5.3e-05 23.0 4.3 9.1 9 0 0 9 9 9 2 EGF-like domain SKG6 PF08693.5 KFO96443.1 - 0.00033 19.8 0.4 0.00033 19.8 0.3 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain EGF_3 PF12947.2 KFO96443.1 - 0.011 15.7 3.1 0.011 15.7 2.2 8.9 9 2 2 11 11 7 0 EGF domain TMEM154 PF15102.1 KFO96443.1 - 0.023 14.3 4.3 0.11 12.1 2.9 1.9 1 1 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 KFO96443.1 - 0.094 12.3 1.0 0.25 10.9 0.0 2.1 2 1 0 2 2 2 0 Rifin/stevor family hEGF PF12661.2 KFO96443.1 - 0.11 12.6 7.4 0.83 9.8 1.1 4.4 2 0 0 2 2 2 0 Human growth factor-like EGF DUF2207 PF09972.4 KFO96443.1 - 0.34 9.4 0.1 0.49 8.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DM PF00751.13 KFO96444.1 - 5.5e-21 73.8 8.3 8.4e-21 73.2 5.8 1.3 1 0 0 1 1 1 1 DM DNA binding domain zf-H2C2_2 PF13465.1 KFO96445.1 - 7.6e-15 54.3 20.2 5.8e-06 26.3 0.5 5.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFO96445.1 - 4.2e-14 51.9 31.9 0.0018 18.5 0.6 6.9 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96445.1 - 5.4e-11 42.0 25.2 0.0028 17.8 0.1 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 KFO96445.1 - 0.23 11.7 6.2 1.6 9.0 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO96445.1 - 0.65 10.2 7.3 26 5.0 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.6 KFO96445.1 - 1.7 8.4 5.5 10 5.9 0.0 4.4 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger Yip1 PF04893.12 KFO96446.1 - 2.7e-20 72.5 13.5 3.4e-20 72.2 9.1 1.3 1 1 0 1 1 1 1 Yip1 domain ELF PF03317.8 KFO96446.1 - 0.092 12.0 1.1 0.13 11.4 0.8 1.2 1 0 0 1 1 1 0 ELF protein T4_deiodinase PF00837.12 KFO96447.1 - 1e-23 83.5 0.0 1.1e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase F5_F8_type_C PF00754.20 KFO96448.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.3 1 1 0 1 1 1 0 F5/8 type C domain APC10 PF03256.11 KFO96448.1 - 0.081 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) LRR_4 PF12799.2 KFO96449.1 - 3.1e-06 26.6 4.7 0.0019 17.7 0.3 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFO96449.1 - 0.00025 20.7 8.5 0.48 10.6 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 KFO96449.1 - 0.0014 18.3 6.0 0.018 14.7 0.1 3.2 2 1 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KFO96449.1 - 0.0026 17.5 5.7 2.9 8.2 0.1 4.1 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 KFO96449.1 - 0.02 14.9 6.7 8.3 7.1 0.3 4.6 4 0 0 4 4 4 0 Leucine rich repeat Ldl_recept_a PF00057.13 KFO96450.1 - 2.2e-11 43.4 30.2 9.8e-05 22.1 2.2 3.4 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A BSMAP PF12280.3 KFO96451.1 - 2.9e-74 249.4 0.4 4.7e-74 248.7 0.2 1.3 1 0 0 1 1 1 1 Brain specific membrane anchored protein Med26 PF08711.6 KFO96452.1 - 2.2e-15 55.8 1.8 2.6e-15 55.6 0.1 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TFIIS_M PF07500.9 KFO96452.1 - 4e-08 33.3 0.1 1.6e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain CUB PF00431.15 KFO96453.1 - 3.2e-92 303.9 0.0 9.1e-32 109.4 0.0 3.0 3 0 0 3 3 3 3 CUB domain CUB_2 PF02408.15 KFO96453.1 - 0.00083 18.8 0.2 0.043 13.3 0.0 2.8 3 0 0 3 3 3 1 CUB-like domain FAD_binding_6 PF00970.19 KFO96454.1 - 4.2e-12 46.0 0.0 7.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFO96454.1 - 5.1e-12 46.3 0.0 1.7e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.4 KFO96454.1 - 7.9e-11 41.2 1.7 7.6e-10 38.0 1.4 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_6 PF08030.7 KFO96454.1 - 0.00037 20.4 0.1 0.06 13.2 0.0 2.7 2 1 0 3 3 3 1 Ferric reductase NAD binding domain TrbC_Ftype PF09673.5 KFO96454.1 - 0.0028 17.2 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein PDCD9 PF07147.7 KFO96455.1 - 1.3e-25 90.1 0.0 2.5e-25 89.1 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) Thi4 PF01946.12 KFO96455.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family SSDP PF04503.8 KFO96456.1 - 1.6e-107 359.5 67.5 3.7e-84 282.9 35.8 2.0 1 1 1 2 2 2 2 Single-stranded DNA binding protein, SSDP PAT1 PF09770.4 KFO96456.1 - 6.6 4.8 12.4 6.4 4.8 8.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 4HBT PF03061.17 KFO96457.1 - 1.1e-17 63.9 0.2 7.2e-10 38.8 0.0 2.5 3 0 0 3 3 3 2 Thioesterase superfamily DUF4149 PF13664.1 KFO96458.1 - 2.6e-22 78.8 9.6 8.4e-22 77.1 4.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4149) TPR_11 PF13414.1 KFO96459.1 - 2.9e-18 65.2 3.7 4e-14 52.0 1.0 2.4 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFO96459.1 - 2.4e-15 55.3 5.1 0.00022 20.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFO96459.1 - 5.3e-12 44.6 4.8 0.0097 15.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFO96459.1 - 3.9e-07 29.9 3.0 7.6e-05 22.5 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFO96459.1 - 5.9e-06 25.6 2.6 0.38 10.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFO96459.1 - 5.5e-05 23.7 0.1 0.013 16.1 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO96459.1 - 0.00065 19.7 1.3 0.0017 18.4 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFO96459.1 - 0.0046 16.6 2.2 2 8.3 0.1 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFO96459.1 - 0.026 14.3 0.1 1.9 8.3 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFO96459.1 - 0.027 14.7 0.2 0.063 13.6 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPM PF04536.9 KFO96459.1 - 0.072 12.9 0.0 0.38 10.6 0.0 2.2 1 1 1 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase HHH_8 PF14716.1 KFO96459.1 - 0.095 12.8 1.4 0.31 11.2 0.2 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain tRNA-synt_2b PF00587.20 KFO96460.1 - 8.7e-36 123.0 0.0 1.1e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFO96460.1 - 7e-07 29.1 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain GAGA PF09237.6 KFO96460.1 - 0.12 11.9 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 GAGA factor Zn-ribbon_8 PF09723.5 KFO96460.1 - 0.14 12.1 0.9 2.3 8.2 0.6 2.6 1 1 1 2 2 2 0 Zinc ribbon domain SHIPPO-rpt PF07004.7 KFO96461.1 - 1.6e-07 31.8 7.7 1.9 9.5 0.1 5.2 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat FAD_binding_4 PF01565.18 KFO96462.1 - 6e-18 64.6 0.1 9.6e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TMEM61 PF15105.1 KFO96463.1 - 1.5e-44 151.9 0.9 1.7e-44 151.7 0.6 1.0 1 0 0 1 1 1 1 TMEM61 protein family Peptidase_S8 PF00082.17 KFO96464.1 - 1.5e-30 106.3 1.3 1.7e-30 106.1 0.9 1.0 1 0 0 1 1 1 1 Subtilase family Hexokinase_1 PF00349.16 KFO96466.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Hexokinase SLY PF12485.3 KFO96467.1 - 1.4e-51 174.7 5.7 1.4e-51 174.7 3.9 2.0 2 0 0 2 2 2 1 Lymphocyte signaling adaptor protein SAM_2 PF07647.12 KFO96467.1 - 2.9e-09 36.6 0.2 6.6e-09 35.4 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFO96467.1 - 3.4e-08 33.5 0.1 8.5e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 KFO96467.1 - 8.9e-05 21.9 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFO96467.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 SH3 domain HSP70 PF00012.15 KFO96468.1 - 8.6e-115 383.9 0.2 1.4e-81 274.2 0.0 2.0 1 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KFO96468.1 - 2.1e-15 56.1 0.2 4.9e-11 41.8 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein StbA PF06406.6 KFO96468.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.6 2 0 0 2 2 2 1 StbA protein BcrAD_BadFG PF01869.15 KFO96468.1 - 0.017 14.4 0.1 5.6 6.1 0.0 3.0 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.5 KFO96468.1 - 0.035 12.9 0.2 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KFO96468.1 - 0.1 11.6 0.1 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 KFO96468.1 - 0.14 11.7 0.1 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFO96468.1 - 0.32 10.8 5.5 58 3.5 0.1 4.1 4 1 0 4 4 4 0 Cell division protein FtsA DUF2547 PF10818.3 KFO96469.1 - 0.18 12.4 1.9 1.7 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Lipase PF00151.14 KFO96470.1 - 1.7e-76 257.6 0.0 2.2e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFO96470.1 - 1.9e-05 24.6 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFO96470.1 - 0.05 13.3 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 KFO96470.1 - 0.091 12.0 0.1 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.11 KFO96470.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase I-set PF07679.11 KFO96471.1 - 3.2e-16 58.9 0.0 4.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96471.1 - 7e-14 51.7 0.0 8.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO96471.1 - 6.2e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO96471.1 - 2.2e-05 24.4 0.1 0.00023 21.2 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFO96471.1 - 0.00015 21.6 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFO96471.1 - 0.00055 19.8 0.0 0.0019 18.0 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain BiPBP_C PF06832.7 KFO96471.1 - 0.008 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family I-set PF07679.11 KFO96472.1 - 2.4e-74 245.2 0.0 4.9e-23 80.7 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96472.1 - 1e-46 156.9 0.0 3.2e-11 43.2 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 KFO96472.1 - 2.7e-38 130.2 1.2 9.5e-09 35.6 0.0 6.3 7 0 0 7 7 7 4 Immunoglobulin domain fn3 PF00041.16 KFO96472.1 - 1.1e-37 128.0 13.8 3.6e-15 55.8 0.7 4.4 4 0 0 4 4 4 3 Fibronectin type III domain ig PF00047.20 KFO96472.1 - 1.6e-33 114.6 1.0 2e-08 34.2 0.1 5.9 5 1 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFO96472.1 - 9.1e-32 109.3 1.5 6.3e-09 35.7 0.0 6.3 3 2 1 4 4 4 4 Immunoglobulin V-set domain Herpes_gE PF02480.11 KFO96472.1 - 0.00019 19.8 0.7 6.8 4.8 0.0 4.6 3 1 2 5 5 5 2 Alphaherpesvirus glycoprotein E Sp38 PF07354.7 KFO96472.1 - 0.0012 17.6 0.0 7.5 5.1 0.0 3.9 4 0 0 4 4 4 2 Zona-pellucida-binding protein (Sp38) Receptor_2B4 PF11465.3 KFO96472.1 - 0.0021 17.9 0.4 10 6.0 0.0 4.3 3 2 1 4 4 4 1 Natural killer cell receptor 2B4 RRN7 PF11781.3 KFO96472.1 - 1 8.9 3.6 16 5.1 0.1 3.5 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 I-set PF07679.11 KFO96473.1 - 1.3e-71 236.5 0.0 5.2e-23 80.7 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96473.1 - 2.4e-40 136.5 0.1 8.5e-09 35.4 0.0 4.9 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.16 KFO96473.1 - 8.3e-34 115.5 10.1 1e-12 48.0 0.4 4.2 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.1 KFO96473.1 - 1.3e-31 108.8 1.4 4.2e-08 33.5 0.2 6.2 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.20 KFO96473.1 - 2.4e-27 94.8 0.5 5.2e-09 36.1 0.3 5.2 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFO96473.1 - 4.5e-25 87.7 2.1 9.2e-10 38.4 0.0 6.2 5 3 0 5 5 5 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO96473.1 - 4.8e-10 39.1 3.6 0.031 14.1 0.0 5.8 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Big_4 PF07532.6 KFO96473.1 - 0.88 9.1 6.6 0.086 12.3 0.5 2.5 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 4) I-set PF07679.11 KFO96474.1 - 2.6e-15 56.0 0.0 3.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96474.1 - 9.4e-13 48.1 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO96474.1 - 2.1e-09 37.7 0.0 3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO96474.1 - 4.8e-05 23.4 0.1 0.00071 19.6 0.1 2.1 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO96474.1 - 6.5e-05 22.7 0.0 0.00026 20.8 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO96474.1 - 0.00036 20.3 0.0 0.00046 20.0 0.0 1.3 1 1 0 1 1 1 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFO96475.1 - 1.2e-23 82.7 0.0 9.6e-11 41.4 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96475.1 - 1.2e-22 79.8 0.0 9.9e-11 41.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 KFO96475.1 - 1.2e-18 66.7 0.2 6.7e-16 57.9 0.0 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 KFO96475.1 - 3.7e-18 65.7 3.4 4.3e-09 36.7 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 KFO96475.1 - 2.7e-16 59.4 0.1 8.3e-08 32.2 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFO96475.1 - 1.9e-13 50.3 0.2 0.013 15.3 0.0 3.9 3 1 0 3 3 3 3 Immunoglobulin V-set domain C1-set PF07654.10 KFO96475.1 - 2.9e-10 39.9 0.4 1.5e-09 37.6 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Vg_Tdu PF07545.9 KFO96476.1 - 6.5e-21 73.4 0.4 1e-20 72.8 0.3 1.3 1 0 0 1 1 1 1 Vestigial/Tondu family Snf7 PF03357.16 KFO96477.1 - 1.7e-44 151.1 28.5 1.7e-44 151.1 19.8 1.4 2 0 0 2 2 2 1 Snf7 DUF3947 PF13135.1 KFO96477.1 - 0.11 12.7 2.9 0.22 11.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) DnaJ-X PF14308.1 KFO96477.1 - 0.55 9.4 18.7 0.046 12.9 9.4 1.8 1 1 1 2 2 2 0 X-domain of DnaJ-containing DUF940 PF06082.6 KFO96477.1 - 0.76 8.2 7.9 0.95 7.9 5.5 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) CorA PF01544.13 KFO96477.1 - 1.6 7.7 8.1 11 4.9 5.4 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SICA_beta PF12878.2 KFO96477.1 - 3.8 7.2 14.1 6.9 6.4 9.7 1.5 1 1 0 1 1 1 0 SICA extracellular beta domain CDC37_N PF03234.9 KFO96477.1 - 4.7 7.5 20.2 8.8 6.6 14.0 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding hDGE_amylase PF14701.1 KFO96477.1 - 5.6 5.7 11.5 8.4 5.1 7.5 1.4 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme SOBP PF15279.1 KFO96477.1 - 8.3 6.6 9.3 9.6 6.4 6.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein LMBR1 PF04791.11 KFO96477.1 - 8.5 4.8 6.9 9 4.7 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein 7tm_1 PF00001.16 KFO96478.1 - 1.2e-80 270.3 10.6 1.7e-80 269.8 7.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFO96478.1 - 3.6e-08 32.8 11.4 4.2e-07 29.3 7.3 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFO96478.1 - 3.6e-07 29.6 17.1 1.9e-06 27.2 11.9 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO96478.1 - 0.00051 19.2 13.8 0.00051 19.2 9.5 2.4 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PDZ PF00595.19 KFO96479.1 - 6.1e-56 186.5 11.0 2.3e-13 50.0 0.3 4.6 5 0 0 5 5 5 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO96479.1 - 6.4e-32 109.2 7.3 1.2e-07 31.4 0.1 4.2 4 0 0 4 4 4 4 PDZ domain GRASP55_65 PF04495.9 KFO96479.1 - 6.3e-09 35.9 1.7 0.071 13.0 0.0 4.0 3 1 1 4 4 4 3 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.1 KFO96479.1 - 6.2e-07 29.1 5.0 0.008 15.9 0.0 4.3 4 0 0 4 4 4 2 Tricorn protease PDZ domain DUF4265 PF14085.1 KFO96479.1 - 0.012 15.3 1.2 0.087 12.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4265) DUF1450 PF07293.6 KFO96479.1 - 0.38 10.7 6.4 4.6 7.2 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1450) ABA_GPCR PF12430.3 KFO96480.1 - 9.2e-63 210.9 12.8 9.2e-63 210.9 8.9 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KFO96480.1 - 3.5e-28 97.4 0.1 1e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) Connexin PF00029.14 KFO96481.1 - 1.6e-52 176.0 0.2 1.6e-52 176.0 0.2 1.6 2 0 0 2 2 2 1 Connexin Connexin50 PF03509.9 KFO96481.1 - 3.9e-37 126.3 0.6 9.8e-37 125.0 0.4 1.7 1 0 0 1 1 1 1 Gap junction alpha-8 protein (Cx50) Connexin_CCC PF10582.4 KFO96481.1 - 2.2e-32 110.6 2.8 4.7e-32 109.5 1.9 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin PF00029.14 KFO96482.1 - 8.1e-53 177.0 0.3 1.8e-52 175.8 0.2 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFO96482.1 - 1.5e-29 101.5 3.1 3.4e-29 100.4 2.2 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Adeno_E3_14_5 PF04834.7 KFO96482.1 - 0.038 14.4 0.2 0.63 10.4 0.0 2.5 2 0 0 2 2 2 0 Early E3 14.5 kDa protein Brr6_like_C_C PF10104.4 KFO96482.1 - 0.28 10.6 2.7 0.27 10.7 0.1 2.3 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain LSR PF05624.9 KFO96482.1 - 1.9 8.2 5.0 0.61 9.8 0.2 2.4 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) His_Phos_2 PF00328.17 KFO96483.1 - 1.3e-32 113.4 0.0 1.7e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BCL9 PF11502.3 KFO96485.1 - 3.8e-22 77.5 2.0 1.7e-21 75.4 1.4 2.3 1 0 0 1 1 1 1 B-cell lymphoma 9 protein Glyco_transf_90 PF05686.7 KFO96486.1 - 5.9e-114 380.8 1.9 7.3e-114 380.5 1.3 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KFO96486.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Tim17 PF02466.14 KFO96487.1 - 2.9e-12 46.7 4.3 4.4e-12 46.1 2.9 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MIT PF04212.13 KFO96487.1 - 0.043 13.7 0.2 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain C2-set_2 PF08205.7 KFO96488.1 - 5.4e-10 39.0 0.6 1.5e-09 37.5 0.1 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFO96488.1 - 7.2e-10 38.7 0.5 7.2e-10 38.7 0.3 1.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO96488.1 - 4.2e-05 23.9 6.8 0.049 14.1 0.1 3.1 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFO96488.1 - 0.0009 19.0 3.3 0.0011 18.8 0.2 2.5 2 2 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96488.1 - 0.0015 18.5 3.9 0.11 12.6 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFO96488.1 - 0.053 13.6 5.7 0.09 12.9 0.3 3.2 2 2 0 2 2 2 0 Immunoglobulin domain C1-set PF07654.10 KFO96488.1 - 0.13 12.2 6.9 1.7 8.7 0.2 3.1 2 2 0 2 2 2 0 Immunoglobulin C1-set domain ADP_ribosyl_GH PF03747.9 KFO96489.1 - 1.1e-47 163.1 1.2 1.3e-47 162.9 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase V-set PF07686.12 KFO96490.1 - 5.3e-55 184.2 1.3 1.1e-10 41.4 0.0 7.3 6 1 0 7 7 7 7 Immunoglobulin V-set domain I-set PF07679.11 KFO96490.1 - 3.8e-38 129.2 0.0 0.0003 20.5 0.0 9.7 7 4 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96490.1 - 2.7e-30 104.3 7.2 2.2e-05 24.4 0.0 7.8 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.20 KFO96490.1 - 8.3e-14 51.4 15.9 0.036 14.1 0.0 10.6 10 2 1 11 11 11 5 Immunoglobulin domain Ig_3 PF13927.1 KFO96490.1 - 9.3e-12 45.2 17.0 0.3 11.6 0.0 10.1 8 5 0 8 8 8 4 Immunoglobulin domain C2-set PF05790.10 KFO96490.1 - 0.0085 16.0 1.0 0.89 9.5 0.0 4.1 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Transglut_N PF00868.15 KFO96490.1 - 0.12 12.3 0.1 29 4.7 0.0 3.0 2 0 0 2 2 2 0 Transglutaminase family V-set PF07686.12 KFO96491.1 - 7.7e-28 96.6 13.2 8.1e-09 35.3 0.1 6.8 6 1 0 6 6 6 5 Immunoglobulin V-set domain Ig_2 PF13895.1 KFO96491.1 - 9e-24 83.4 6.3 1.7e-05 24.8 0.0 5.8 5 1 0 5 5 5 5 Immunoglobulin domain I-set PF07679.11 KFO96491.1 - 1e-21 76.5 7.0 4.5e-05 23.2 0.0 8.0 7 1 1 8 8 8 5 Immunoglobulin I-set domain ig PF00047.20 KFO96491.1 - 7.9e-16 57.9 12.1 0.00027 21.0 0.2 9.0 8 3 0 8 8 8 4 Immunoglobulin domain Ig_3 PF13927.1 KFO96491.1 - 1.6e-10 41.2 7.6 0.16 12.4 0.0 7.6 6 4 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 KFO96492.1 - 4.3e-05 23.3 0.3 7.3e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFO96492.1 - 0.0046 17.0 0.0 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFO96492.1 - 0.0067 16.2 0.2 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96493.1 - 0.00012 22.1 0.3 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFO96493.1 - 0.00038 20.5 0.3 0.43 10.7 0.0 2.7 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 KFO96493.1 - 0.00058 19.6 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFO96493.1 - 0.0082 16.6 1.6 0.25 11.8 0.3 2.8 2 1 0 2 2 2 1 Immunoglobulin domain DUF3481 PF11980.3 KFO96493.1 - 0.0095 15.7 1.4 0.018 14.8 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) V-set PF07686.12 KFO96493.1 - 0.018 14.9 0.1 1.1 9.1 0.0 2.4 1 1 1 2 2 2 0 Immunoglobulin V-set domain stn_TNFRSF12A PF12191.3 KFO96493.1 - 0.026 14.5 0.1 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Herpes_gE PF02480.11 KFO96493.1 - 0.057 11.6 0.0 0.72 8.0 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Orthoreo_P10 PF07204.6 KFO96493.1 - 0.097 12.4 1.2 0.18 11.5 0.9 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.1 KFO96493.1 - 0.098 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HAMP PF00672.20 KFO96494.1 - 0.29 11.3 1.9 19 5.5 0.0 3.2 2 1 0 2 2 2 0 HAMP domain zf-H2C2_2 PF13465.1 KFO96495.1 - 4.6e-56 184.4 47.7 2.6e-08 33.7 0.4 9.0 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFO96495.1 - 1.4e-45 150.8 63.1 8.3e-08 32.1 0.5 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96495.1 - 2.2e-26 90.2 53.4 0.00031 20.8 0.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO96495.1 - 1.9e-23 81.5 59.4 0.00061 19.5 0.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO96495.1 - 1.3e-11 44.2 28.3 0.058 13.5 0.5 7.5 8 0 0 8 8 7 4 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 KFO96495.1 - 8.7e-09 34.9 23.0 0.16 11.7 0.2 7.9 8 0 0 8 8 8 3 XPA protein N-terminal C1_1 PF00130.17 KFO96495.1 - 2.1e-07 30.5 24.8 0.0091 15.7 2.1 5.5 1 1 7 8 8 8 6 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 KFO96495.1 - 1.7e-06 27.8 33.0 1.7 8.6 0.1 7.8 6 1 0 7 7 7 3 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 KFO96495.1 - 1.7e-05 24.1 30.3 1.2 8.6 0.1 8.1 8 0 0 8 8 8 3 DNA directed RNA polymerase, 7 kDa subunit RRN7 PF11781.3 KFO96495.1 - 0.00048 19.5 21.8 0.16 11.5 0.1 6.9 7 0 0 7 7 7 1 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 KFO96495.1 - 0.0009 19.0 30.1 6.2 6.7 5.4 5.3 2 2 0 2 2 2 0 Double zinc ribbon FYDLN_acid PF09538.5 KFO96495.1 - 0.0036 17.8 11.2 17 6.0 0.0 6.3 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) TFIIS_C PF01096.13 KFO96495.1 - 0.0066 16.0 27.7 7.4 6.2 0.1 7.8 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) C1_3 PF07649.7 KFO96495.1 - 0.0092 15.9 26.8 1.9 8.5 0.1 7.2 8 0 0 8 8 8 1 C1-like domain Elf1 PF05129.8 KFO96495.1 - 0.013 15.1 16.2 0.45 10.2 0.2 4.3 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like C1_4 PF07975.7 KFO96495.1 - 0.022 14.7 26.6 0.41 10.6 0.5 5.8 1 1 4 6 6 6 0 TFIIH C1-like domain DrsE PF02635.10 KFO96495.1 - 0.027 14.5 0.2 0.17 11.9 0.0 2.4 3 0 0 3 3 3 0 DsrE/DsrF-like family zf-UBP PF02148.14 KFO96495.1 - 0.1 12.7 39.3 1.6 8.8 0.7 6.3 1 1 5 6 6 6 0 Zn-finger in ubiquitin-hydrolases and other protein BolA PF01722.13 KFO96495.1 - 0.18 11.8 9.6 3.7 7.5 0.1 4.1 3 2 0 3 3 3 0 BolA-like protein GF_recep_IV PF14843.1 KFO96495.1 - 0.2 11.3 19.3 0.7 9.5 3.0 3.0 1 1 2 3 3 3 0 Growth factor receptor domain IV HTH_18 PF12833.2 KFO96495.1 - 0.26 11.3 1.8 1.5e+02 2.5 0.0 4.4 5 1 0 5 5 4 0 Helix-turn-helix domain YhfH PF14149.1 KFO96495.1 - 0.27 11.0 31.6 4.4 7.1 0.1 7.9 8 0 0 8 8 8 0 YhfH-like protein LIM PF00412.17 KFO96495.1 - 0.38 10.8 30.3 2.4 8.3 0.2 5.9 2 2 4 6 6 6 0 LIM domain zf-LYAR PF08790.6 KFO96495.1 - 0.53 10.0 30.1 3.4 7.4 0.1 7.8 8 0 0 8 8 8 0 LYAR-type C2HC zinc finger Zn_Tnp_IS1595 PF12760.2 KFO96495.1 - 0.6 9.9 40.7 5.2 6.9 3.7 5.9 3 2 3 6 6 6 0 Transposase zinc-ribbon domain CpXC PF14353.1 KFO96495.1 - 0.73 9.7 23.4 4 7.4 0.2 7.0 2 2 3 6 6 6 0 CpXC protein zf-H2C2_5 PF13909.1 KFO96495.1 - 0.8 10.0 0.1 0.4 11.0 2.5 8.8 8 1 0 8 8 8 0 C2H2-type zinc-finger domain Siva PF05458.7 KFO96495.1 - 1.6 8.2 11.3 1.9 8.0 1.3 3.0 1 1 2 3 3 3 0 Cd27 binding protein (Siva) Zn_ribbon_recom PF13408.1 KFO96495.1 - 3 8.1 36.2 47 4.3 6.7 5.9 2 2 2 4 4 3 0 Recombinase zinc beta ribbon domain Yippee-Mis18 PF03226.9 KFO96495.1 - 5.1 7.2 28.5 7.3 6.7 1.9 6.2 3 2 2 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RING_3 PF14369.1 KFO96495.1 - 6 6.9 30.6 19 5.3 0.1 7.7 8 0 0 8 8 8 0 zinc-finger LSR PF05624.9 KFO96496.1 - 7.4e-25 86.4 32.8 1.1e-24 85.8 22.8 1.2 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.12 KFO96496.1 - 3.5e-05 23.6 0.1 0.00085 19.1 0.1 2.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFO96497.1 - 3.9e-13 49.3 1.9 7.5e-06 25.9 0.5 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFO96497.1 - 2e-12 46.7 0.2 8.3e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO96497.1 - 1.5e-11 44.2 4.1 2e-07 31.0 1.1 2.2 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFO96497.1 - 7.5e-10 38.7 3.3 1.2e-06 28.3 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO96497.1 - 1.8e-09 37.9 2.8 2.6e-06 27.8 1.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFO96497.1 - 0.00025 19.4 4.0 1.4 7.1 0.0 3.0 1 1 2 3 3 3 3 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 KFO96497.1 - 0.0036 17.1 0.3 0.0074 16.1 0.1 1.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Shisa PF13908.1 KFO96497.1 - 0.52 10.4 4.9 0.44 10.7 2.6 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 KFO96497.1 - 0.58 9.7 1.9 0.87 9.1 1.3 1.2 1 0 0 1 1 1 0 IncA protein Lamp PF01299.12 KFO96497.1 - 0.77 8.8 4.9 0.39 9.8 0.8 2.0 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DSPc PF00782.15 KFO96498.1 - 7.3e-26 90.3 0.0 2e-25 88.9 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pou PF00157.12 KFO96499.1 - 2e-39 133.0 0.1 5e-39 131.8 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFO96499.1 - 1.3e-17 63.1 2.7 3.3e-17 61.8 1.9 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO96499.1 - 0.12 12.1 0.1 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain TCR_zetazeta PF11628.3 KFO96500.1 - 4.6e-16 57.9 0.2 6.6e-16 57.4 0.1 1.3 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain ITAM PF02189.10 KFO96500.1 - 2.7e-09 36.6 2.6 0.0011 19.0 0.1 2.9 3 0 0 3 3 3 2 Immunoreceptor tyrosine-based activation motif Pyrid_oxidase_2 PF13883.1 KFO96501.1 - 6.1e-42 143.2 0.0 6.7e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CAP-ZIP_m PF15255.1 KFO96502.1 - 1e-21 77.3 0.6 1e-21 77.3 0.4 2.5 2 0 0 2 2 2 1 WASH complex subunit CAP-Z interacting, central region TPR_11 PF13414.1 KFO96504.1 - 1e-44 149.9 32.4 4.6e-15 55.0 1.7 6.4 4 2 3 7 7 7 7 TPR repeat TPR_2 PF07719.12 KFO96504.1 - 7.9e-41 134.7 15.6 1e-08 34.4 0.1 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.23 KFO96504.1 - 4.4e-39 130.5 20.2 3.7e-10 38.9 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 KFO96504.1 - 9e-31 103.3 13.4 1.8e-05 24.1 0.0 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat DUF1736 PF08409.6 KFO96504.1 - 3.2e-29 100.3 1.5 7.7e-29 99.0 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_16 PF13432.1 KFO96504.1 - 1.3e-28 98.9 4.1 4.5e-07 30.3 0.1 6.7 3 2 5 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 KFO96504.1 - 3e-28 95.6 25.0 2.6e-06 27.1 0.2 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 KFO96504.1 - 1.9e-24 85.3 17.7 9.8e-08 31.8 0.1 7.0 2 1 4 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 KFO96504.1 - 1.2e-22 80.0 12.7 9.4e-08 32.2 0.6 6.8 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96504.1 - 2.2e-20 71.2 7.1 7e-05 23.1 0.0 8.7 4 4 4 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFO96504.1 - 1.5e-11 43.9 13.0 0.05 14.0 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFO96504.1 - 5.9e-09 35.6 1.9 0.0009 19.0 0.1 5.1 3 2 2 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO96504.1 - 2.5e-08 33.9 7.3 0.05 13.7 0.2 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFO96504.1 - 6.9e-08 31.7 8.3 2.9 7.9 0.0 7.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFO96504.1 - 3.2e-05 23.7 15.1 2.1 8.3 1.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.5 KFO96504.1 - 0.00025 19.9 7.7 0.039 12.7 0.4 3.0 1 1 2 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) PMT_2 PF13231.1 KFO96504.1 - 0.00049 20.0 7.6 0.00049 20.0 5.3 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2929 PF11151.3 KFO96504.1 - 0.012 15.7 0.1 0.062 13.3 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) TPR_15 PF13429.1 KFO96504.1 - 0.019 14.0 9.7 0.0087 15.1 3.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFO96504.1 - 0.066 13.1 3.1 13 5.7 0.0 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SIC PF03482.8 KFO96505.1 - 0.7 9.4 4.6 0.75 9.3 3.2 1.0 1 0 0 1 1 1 0 sic protein BH4 PF02180.12 KFO96505.1 - 6.8 6.2 11.2 49 3.5 0.7 4.4 1 1 4 5 5 5 0 Bcl-2 homology region 4 SCF PF02404.10 KFO96506.1 - 1.2e-150 500.1 2.1 1.4e-150 499.9 1.4 1.0 1 0 0 1 1 1 1 Stem cell factor PT PF04886.7 KFO96507.1 - 0.0047 16.2 0.0 3.7 6.9 0.0 3.8 1 1 0 1 1 1 1 PT repeat Yae1_N PF09811.4 KFO96508.1 - 2.2e-20 71.9 63.9 1.5e+04 -24.5 44.3 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DSPc PF00782.15 KFO96509.1 - 3.7e-43 146.3 0.0 5.2e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO96509.1 - 6.5e-05 22.3 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KFO96509.1 - 7e-05 23.1 0.0 0.00034 20.9 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 KFO96509.1 - 0.0063 16.5 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate WD40 PF00400.27 KFO96510.1 - 2.5e-68 223.7 20.5 1.7e-13 49.8 0.8 6.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KFO96510.1 - 9.8e-09 35.1 0.5 2.5e-05 24.0 0.0 3.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFO96510.1 - 5.4e-06 24.8 6.1 0.2 9.7 0.0 5.0 2 1 1 5 5 5 3 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 KFO96510.1 - 0.00038 19.7 0.3 0.83 9.0 0.0 3.4 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 KFO96510.1 - 0.0011 17.3 0.1 1.2 7.4 0.0 3.0 1 1 3 4 4 4 3 Cytochrome D1 heme domain PD40 PF07676.7 KFO96510.1 - 0.025 14.2 1.2 3.5 7.3 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF2415 PF10313.4 KFO96510.1 - 0.069 12.8 0.3 1.8 8.2 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) Glycos_transf_2 PF00535.21 KFO96511.1 - 9.8e-32 109.9 0.0 2e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFO96511.1 - 6.8e-10 39.0 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFO96511.1 - 1.7e-08 34.5 0.0 3.5e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFO96511.1 - 3.9e-06 26.2 0.0 8.7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFO96511.1 - 1.6e-05 24.1 0.0 6.2e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 E1-E2_ATPase PF00122.15 KFO96512.1 - 7.7e-56 188.6 0.3 1.6e-55 187.6 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFO96512.1 - 2.8e-44 150.7 4.0 2.8e-44 150.7 2.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.3 KFO96512.1 - 1.4e-33 115.0 2.1 1e-15 57.8 0.7 2.7 1 1 1 2 2 2 2 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.21 KFO96512.1 - 4.1e-24 86.1 0.0 3.3e-23 83.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFO96512.1 - 3.8e-16 58.3 0.0 1.6e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFO96512.1 - 1.1e-14 55.0 0.0 2.6e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFO96512.1 - 1.6e-14 53.6 0.0 4e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFO96512.1 - 5.5e-07 29.4 1.6 0.00012 21.7 0.4 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase LRR_8 PF13855.1 KFO96514.1 - 1.6e-22 78.9 8.7 6.7e-11 41.7 0.4 3.6 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFO96514.1 - 2.1e-16 59.1 8.9 0.00017 21.1 0.1 4.5 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96514.1 - 2.7e-13 47.9 10.4 0.38 10.9 0.0 7.3 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_5 PF13306.1 KFO96514.1 - 1.1e-06 28.3 0.3 3.9e-05 23.3 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFO96514.1 - 1.1e-05 25.0 2.3 0.00078 19.0 0.7 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRRNT PF01462.13 KFO96514.1 - 1.4e-05 24.4 2.6 1.4e-05 24.4 1.8 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFO96514.1 - 4.8e-05 23.0 8.1 9.1 6.7 0.0 6.1 6 0 0 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 KFO96514.1 - 6.6e-05 22.4 5.6 0.56 10.6 0.0 5.7 6 0 0 6 6 6 1 Leucine rich repeat LRR_8 PF13855.1 KFO96515.1 - 2.3e-33 113.7 27.0 3.8e-12 45.7 3.6 6.2 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFO96515.1 - 3.2e-22 77.6 32.1 3e-06 26.7 0.9 7.9 4 3 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96515.1 - 2.9e-18 63.0 27.4 0.22 11.6 0.0 11.5 11 1 1 12 12 12 8 Leucine Rich Repeat LRR_6 PF13516.1 KFO96515.1 - 1.4e-09 37.0 21.5 0.26 11.4 0.2 9.1 8 2 1 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 KFO96515.1 - 4e-08 32.1 24.0 8.7 7.0 0.1 10.6 11 0 0 11 11 11 1 Leucine rich repeat LRRNT PF01462.13 KFO96515.1 - 1.2e-05 24.6 3.6 1.2e-05 24.6 2.5 3.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.1 KFO96515.1 - 1.7e-05 24.4 3.3 0.0017 17.9 0.7 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.1 KFO96515.1 - 2.2e-05 24.1 1.6 0.0035 17.0 0.4 3.0 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) CRT10 PF08728.5 KFO96515.1 - 0.012 13.6 0.0 0.017 13.1 0.0 1.2 1 0 0 1 1 1 0 CRT10 LRR_8 PF13855.1 KFO96516.1 - 4.6e-38 128.7 48.7 4.9e-13 48.6 2.9 6.2 3 1 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 KFO96516.1 - 3.6e-29 99.8 36.2 6.7e-08 31.9 0.9 7.7 1 1 7 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96516.1 - 3.5e-24 81.1 27.5 0.047 13.7 0.2 11.4 9 2 2 11 11 11 9 Leucine Rich Repeat LRR_6 PF13516.1 KFO96516.1 - 1e-13 49.7 32.2 0.048 13.7 0.0 10.8 11 0 0 11 11 11 7 Leucine Rich repeat LRR_7 PF13504.1 KFO96516.1 - 2.3e-11 41.9 29.6 0.8 10.1 0.0 10.6 11 0 0 11 11 11 4 Leucine rich repeat LRRNT PF01462.13 KFO96516.1 - 4.1e-08 32.4 2.3 4.1e-08 32.4 1.6 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFO96516.1 - 1.6e-06 27.8 3.9 0.0014 18.3 0.2 3.4 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFO96516.1 - 0.00029 20.4 7.2 0.37 10.3 0.1 3.2 1 1 2 3 3 3 3 Leucine-rich repeat DUF4292 PF14125.1 KFO96516.1 - 0.59 9.5 3.9 12 5.2 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4292) LRR_8 PF13855.1 KFO96517.1 - 1e-38 130.8 20.7 5.7e-14 51.6 4.9 4.6 4 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFO96517.1 - 4.8e-27 93.0 25.7 4.5e-08 32.5 2.1 5.8 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96517.1 - 4.7e-17 59.3 18.2 0.04 13.9 0.1 10.0 9 1 1 10 10 10 4 Leucine Rich Repeat LRR_5 PF13306.1 KFO96517.1 - 1.6e-11 44.0 3.6 2.3e-05 24.1 0.3 3.1 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO96517.1 - 6.6e-10 37.5 13.9 0.42 11.0 0.2 8.0 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 KFO96517.1 - 1.2e-08 34.1 22.1 0.077 13.0 0.0 8.7 9 0 0 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 KFO96517.1 - 1.9e-08 34.0 4.0 0.0027 17.2 0.8 3.0 1 1 1 3 3 3 2 Leucine-rich repeat LRRNT PF01462.13 KFO96517.1 - 4.6e-07 29.1 4.8 4.6e-07 29.1 3.3 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain FNIP PF05725.7 KFO96517.1 - 0.41 10.6 6.2 4.8 7.2 0.2 3.4 2 1 0 2 2 2 0 FNIP Repeat BTG PF07742.7 KFO96518.1 - 1.9e-32 111.2 0.0 2.4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 BTG family RhoGEF PF00621.15 KFO96519.1 - 6.4e-19 68.5 4.7 6.4e-19 68.5 3.2 1.6 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 KFO96519.1 - 0.0011 18.9 5.6 0.002 18.0 0.3 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain Imm42 PF15601.1 KFO96519.1 - 0.02 14.2 1.4 0.1 12.0 0.1 2.4 2 0 0 2 2 2 0 Immunity protein 42 FYVE PF01363.16 KFO96520.1 - 2.9e-20 71.9 10.9 2.9e-20 71.9 7.5 2.7 2 0 0 2 2 2 1 FYVE zinc finger CENP-F_leu_zip PF10473.4 KFO96520.1 - 0.00053 19.8 20.4 0.00053 19.8 14.2 14.7 3 3 12 15 15 15 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 KFO96520.1 - 0.0026 17.3 17.0 0.0026 17.3 11.8 12.3 1 1 12 13 13 13 3 Ezrin/radixin/moesin family IBR PF01485.16 KFO96520.1 - 0.0032 17.3 4.7 0.017 14.9 3.2 2.3 1 0 0 1 1 1 1 IBR domain Filament PF00038.16 KFO96520.1 - 0.0036 16.8 281.7 0.024 14.0 43.2 11.7 1 1 7 8 8 8 4 Intermediate filament protein HrpB7 PF09486.5 KFO96520.1 - 0.0058 16.5 10.4 0.0058 16.5 7.2 13.6 2 2 10 15 15 15 2 Bacterial type III secretion protein (HrpB7) C1_4 PF07975.7 KFO96520.1 - 0.3 11.1 6.8 2.1 8.4 4.7 2.6 1 0 0 1 1 1 0 TFIIH C1-like domain Lipase_GDSL_2 PF13472.1 KFO96521.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NUDIX PF00293.23 KFO96522.1 - 1.4e-15 57.1 0.2 1.7e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Biopterin_H PF00351.16 KFO96523.1 - 4e-182 604.3 0.2 4.9e-182 604.0 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Peptidase_M1 PF01433.15 KFO96524.1 - 1.2e-108 363.7 0.1 1.6e-108 363.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFO96524.1 - 1.1e-44 153.0 2.5 1.6e-44 152.4 0.9 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFO96524.1 - 4.4e-16 59.1 0.1 4.4e-16 59.1 0.1 2.2 3 0 0 3 3 3 1 Peptidase MA superfamily dUTPase PF00692.14 KFO96525.1 - 3.3e-21 75.0 0.2 4.3e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFO96525.1 - 0.0027 17.6 0.7 0.0085 15.9 0.2 2.0 2 1 1 3 3 3 1 Retroviral aspartyl protease THP2 PF09432.5 KFO96527.1 - 0.027 14.3 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 Tho complex subunit THP2 Peptidase_C65 PF10275.4 KFO96527.1 - 0.037 13.3 0.4 0.063 12.6 0.2 1.4 1 1 0 1 1 1 0 Peptidase C65 Otubain Mononeg_mRNAcap PF14318.1 KFO96527.1 - 0.11 11.4 0.7 0.16 10.9 0.4 1.3 1 1 0 1 1 1 0 Mononegavirales mRNA-capping region V Cohesin_HEAT PF12765.2 KFO96528.1 - 3.6e-15 55.5 0.3 5.9e-15 54.8 0.2 1.4 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KFO96528.1 - 6.7e-06 25.7 0.4 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.1 KFO96528.1 - 9e-06 26.0 0.4 0.0022 18.4 0.1 1.9 1 1 2 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 KFO96528.1 - 0.0059 16.8 0.1 0.01 16.1 0.1 1.5 1 1 0 1 1 1 1 HEAT repeats Cnd3 PF12719.2 KFO96528.1 - 0.0073 15.3 0.1 0.19 10.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain MMS19_N PF14500.1 KFO96528.1 - 0.06 12.6 0.1 3 7.0 0.0 2.0 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II CcmH PF03918.9 KFO96528.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF3385 PF11865.3 KFO96528.1 - 0.13 12.1 0.0 0.14 12.1 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) Nipped-B_C PF12830.2 KFO96529.1 - 3e-63 212.8 3.1 4.9e-63 212.1 0.7 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.1 KFO96529.1 - 0.0015 18.7 0.0 0.023 14.9 0.0 3.1 3 0 0 3 3 3 1 HEAT repeats DUF3453 PF11935.3 KFO96530.1 - 1.1e-58 198.5 0.0 1.9e-58 197.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Symplekin_C PF12295.3 KFO96530.1 - 1.3e-09 38.2 0.1 3.2e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal HEAT PF02985.17 KFO96530.1 - 0.17 12.0 0.5 3 8.1 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat Claudin_2 PF13903.1 KFO96531.1 - 5.8e-13 48.9 5.5 6.9e-13 48.6 3.8 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFO96531.1 - 0.0003 20.4 5.1 0.00043 19.9 3.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Apq12 PF12716.2 KFO96531.1 - 0.079 12.6 0.7 0.2 11.3 0.5 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DUF2347 PF09804.4 KFO96532.1 - 2.3e-73 246.9 0.0 3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KFO96532.1 - 9.7e-13 47.8 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KFO96532.1 - 4.8e-10 38.4 0.1 0.0021 16.5 0.0 3.2 3 0 0 3 3 3 3 Transport protein Avl9 Ph1570 PF09638.5 KFO96532.1 - 0.075 12.8 0.1 0.51 10.1 0.1 2.3 2 0 0 2 2 2 0 Ph1570 protein Pkinase PF00069.20 KFO96533.1 - 7.4e-48 162.9 0.0 9.8e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96533.1 - 5.2e-23 81.4 0.0 8.8e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FYDLN_acid PF09538.5 KFO96533.1 - 0.025 15.1 2.1 0.025 15.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2116 PF09889.4 KFO96533.1 - 0.054 13.3 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pox_ser-thr_kin PF05445.6 KFO96533.1 - 0.21 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SSB PF00436.20 KFO96534.1 - 1.7e-31 108.1 0.2 2e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family bZIP_1 PF00170.16 KFO96535.1 - 1.4e-14 53.7 16.2 5.9e-14 51.7 11.0 2.1 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KFO96535.1 - 3.2e-10 39.6 10.5 3.2e-10 39.6 7.2 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFO96535.1 - 1.1e-06 28.7 10.7 2.5e-06 27.7 7.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF904 PF06005.7 KFO96535.1 - 0.0078 16.4 2.0 0.0078 16.4 1.4 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF904) FlaC_arch PF05377.6 KFO96535.1 - 0.0081 16.0 1.2 0.021 14.6 0.9 1.7 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 KFO96535.1 - 0.027 14.5 8.0 0.05 13.7 5.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.6 KFO96535.1 - 0.065 10.7 2.6 0.095 10.2 1.8 1.1 1 0 0 1 1 1 0 Prominin APG6 PF04111.7 KFO96535.1 - 0.074 12.0 7.4 0.12 11.3 5.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2106 PF09879.4 KFO96535.1 - 0.092 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) TBCA PF02970.11 KFO96535.1 - 0.13 12.3 8.9 0.31 11.1 6.2 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A ADIP PF11559.3 KFO96535.1 - 0.19 11.6 10.8 0.33 10.8 7.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Herpes_BLRF2 PF05812.7 KFO96535.1 - 0.37 10.5 10.0 0.93 9.3 2.8 2.6 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF1664 PF07889.7 KFO96535.1 - 0.6 9.9 4.4 0.97 9.2 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 KFO96535.1 - 0.72 10.3 4.3 2.5 8.5 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) V_ATPase_I PF01496.14 KFO96535.1 - 1.4 6.6 5.1 2.1 6.1 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 KFO96535.1 - 8.4 6.2 8.9 9.4 6.1 2.0 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DAGK_acc PF00609.14 KFO96536.1 - 3.1e-47 160.7 0.0 6.6e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFO96536.1 - 4.5e-32 110.2 0.0 9.8e-32 109.1 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.2 KFO96536.1 - 1.3e-28 99.1 5.8 1.7e-13 50.7 0.1 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) C1_1 PF00130.17 KFO96536.1 - 6.6e-15 54.5 27.4 8.3e-11 41.4 10.5 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_5 PF13857.1 KFO96536.1 - 6.5e-12 45.2 0.2 8.9e-07 28.9 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO96536.1 - 3.7e-11 43.2 0.0 7.5e-07 29.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFO96536.1 - 5.1e-11 41.8 0.7 2.2e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFO96536.1 - 1.5e-09 37.1 0.1 0.0024 17.9 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat PHD_2 PF13831.1 KFO96536.1 - 3.2 7.1 9.7 8.8 5.7 1.7 2.8 2 0 0 2 2 2 0 PHD-finger PTN_MK_C PF01091.13 KFO96537.1 - 8.5e-30 102.5 10.3 8.5e-30 102.5 7.1 2.8 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N PF05196.8 KFO96537.1 - 5.3e-28 96.7 18.0 5.3e-28 96.7 12.5 2.8 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, N-terminal domain ATP-synt_8 PF00895.15 KFO96537.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.8 3 0 0 3 3 3 0 ATP synthase protein 8 OAD_gamma PF04277.8 KFO96537.1 - 0.31 11.4 4.0 1 9.7 0.1 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain 7tm_1 PF00001.16 KFO96538.1 - 6.8e-82 274.4 4.4 1.1e-81 273.7 3.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3697 PF12478.3 KFO96539.1 - 6.1e-20 70.5 0.6 1.3e-19 69.5 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 UBA_4 PF14555.1 KFO96539.1 - 1.9e-05 24.0 0.0 4.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 KFO96539.1 - 2.3e-05 24.0 0.1 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 KFO96539.1 - 0.047 13.1 0.1 0.14 11.6 0.1 1.9 1 0 0 1 1 1 0 CUE domain UQ_con PF00179.21 KFO96540.1 - 3.5e-32 110.7 0.3 4.6e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFO96540.1 - 0.11 12.2 1.1 0.3 10.8 0.1 2.1 2 1 0 2 2 2 0 Prokaryotic E2 family B 7tm_1 PF00001.16 KFO96541.1 - 1e-06 28.0 0.7 1.5e-06 27.5 0.1 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) GRIP PF01465.15 KFO96543.1 - 7.2e-17 60.6 0.0 3.2e-16 58.5 0.0 2.2 1 0 0 1 1 1 1 GRIP domain Filament PF00038.16 KFO96543.1 - 0.012 15.1 3.3 0.012 15.1 2.3 5.7 2 1 1 3 3 3 0 Intermediate filament protein DUF3584 PF12128.3 KFO96543.1 - 2.8 5.1 81.8 0.05 10.9 10.8 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) SPA PF08616.5 KFO96544.1 - 1.7e-13 50.2 0.0 6.5e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.16 KFO96544.1 - 4.5e-07 29.7 4.3 4.5e-07 29.7 3.0 2.3 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.4 KFO96544.1 - 0.00033 19.2 0.0 0.00054 18.5 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SBF2 PF12335.3 KFO96545.1 - 5.1e-108 359.5 2.7 8.8e-108 358.8 1.9 1.4 1 0 0 1 1 1 1 Myotubularin protein Myotub-related PF06602.9 KFO96545.1 - 4.2e-100 334.9 0.0 6.7e-100 334.3 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DENN PF02141.16 KFO96545.1 - 5.3e-57 192.5 0.3 1.1e-56 191.4 0.2 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFO96545.1 - 3.8e-21 74.8 1.7 9.9e-21 73.4 1.2 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFO96545.1 - 8.3e-17 61.0 0.0 2.3e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 dDENN domain PH PF00169.24 KFO96545.1 - 3.7e-12 46.3 0.0 8.9e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KFO96545.1 - 7.8e-11 41.3 0.0 7.8e-10 38.1 0.0 2.6 3 0 0 3 3 3 1 GRAM domain PH_11 PF15413.1 KFO96545.1 - 5.7e-05 23.3 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SPA PF08616.5 KFO96545.1 - 7.7e-05 22.3 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis PH_9 PF15410.1 KFO96545.1 - 0.11 12.6 0.6 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain SWIRM PF04433.12 KFO96546.1 - 6.8e-34 115.8 2.0 1e-33 115.2 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 KFO96546.1 - 3e-09 36.7 0.2 6.4e-09 35.7 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFO96546.1 - 6.8e-08 32.5 0.0 2e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2618 PF10940.3 KFO96546.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) HA2 PF04408.18 KFO96547.1 - 2.2e-15 56.5 0.1 1.5e-14 53.8 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFO96547.1 - 1.8e-12 46.9 0.1 4.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 KFO96547.1 - 2.1e-10 41.0 2.0 9.1e-05 22.9 0.4 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 KFO96547.1 - 8.4e-07 28.6 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KFO96547.1 - 1.2e-06 28.2 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KFO96547.1 - 0.003 17.7 0.0 0.013 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFO96547.1 - 0.0041 16.8 0.1 0.016 14.9 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain HEAT_2 PF13646.1 KFO96547.1 - 0.029 14.6 0.7 0.15 12.3 0.2 2.5 2 0 0 2 2 2 0 HEAT repeats PhoH PF02562.11 KFO96547.1 - 0.074 12.2 0.0 0.81 8.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 KFO96547.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 KFO96547.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KFO96547.1 - 0.13 12.5 0.0 0.5 10.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 KFO96547.1 - 0.23 11.7 0.0 0.45 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tubulin-binding PF00418.14 KFO96548.1 - 2.6e-46 154.9 23.3 1.4e-17 63.0 3.9 3.1 3 0 0 3 3 3 3 Tau and MAP protein, tubulin-binding repeat SBP_bac_3 PF00497.15 KFO96552.1 - 0.00047 19.4 0.0 0.0006 19.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.21 KFO96552.1 - 0.0017 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel CSD PF00313.17 KFO96554.1 - 6.4e-18 64.2 0.1 1.4e-17 63.2 0.1 1.6 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.18 KFO96554.1 - 3.1e-05 23.6 14.4 0.00045 20.0 2.6 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KFO96554.1 - 0.00018 21.1 11.3 0.058 13.0 1.4 2.5 2 0 0 2 2 2 2 Zinc knuckle Tmemb_cc2 PF10267.4 KFO96554.1 - 0.18 10.3 2.0 0.21 10.1 1.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein zf-CCHC_6 PF15288.1 KFO96554.1 - 0.66 9.6 7.3 5.9 6.6 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF2946 PF11162.3 KFO96554.1 - 4.8 7.4 7.3 3 8.0 3.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) Popeye PF04831.8 KFO96555.1 - 1.3e-141 466.5 0.1 6e-71 237.1 0.0 2.2 2 0 0 2 2 2 2 Popeye protein conserved region cNMP_binding PF00027.24 KFO96555.1 - 5.2e-07 29.3 0.7 0.015 15.1 0.0 3.7 3 2 0 3 3 3 2 Cyclic nucleotide-binding domain Peptidase_S9_N PF02897.10 KFO96556.1 - 3e-146 487.2 0.0 3.6e-146 486.9 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 KFO96556.1 - 1.6e-69 233.3 0.0 2.5e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KFO96556.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase APG5 PF04106.7 KFO96557.1 - 4.7e-69 231.8 0.2 6.1e-69 231.4 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Crystall PF00030.14 KFO96559.1 - 7.9e-126 410.2 2.0 3.9e-27 93.9 0.0 6.4 6 0 0 6 6 6 6 Beta/Gamma crystallin Ricin_B_lectin PF00652.17 KFO96559.1 - 1.7e-13 50.6 0.3 3.9e-13 49.4 0.1 1.7 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Crystall_3 PF08964.5 KFO96559.1 - 0.0024 17.5 4.0 15 5.3 0.0 6.3 6 2 3 9 9 9 1 Beta/Gamma crystallin RicinB_lectin_2 PF14200.1 KFO96559.1 - 0.037 14.3 0.0 0.68 10.3 0.0 2.3 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like ADH_zinc_N_2 PF13602.1 KFO96560.1 - 6.8e-23 81.9 0.0 1.1e-22 81.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFO96560.1 - 2.5e-14 52.9 0.1 4.6e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFO96560.1 - 3.9e-11 42.6 0.0 2.1e-10 40.3 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KFO96560.1 - 0.0052 16.3 0.2 0.0083 15.7 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Eno-Rase_NADH_b PF12242.3 KFO96560.1 - 0.0072 16.0 0.4 0.015 15.0 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KFO96560.1 - 0.0084 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KFO96560.1 - 0.037 13.1 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amidase PF01425.16 KFO96561.1 - 1.6e-125 419.4 0.0 9.5e-125 416.8 0.0 1.8 1 1 0 1 1 1 1 Amidase DUF2863 PF11062.3 KFO96562.1 - 0.039 12.0 0.1 0.057 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) FAM176 PF14851.1 KFO96562.1 - 0.094 12.3 1.9 0.15 11.7 1.3 1.3 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.3 KFO96562.1 - 0.19 11.6 7.7 0.31 10.9 5.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 KFO96562.1 - 0.69 10.1 6.8 1.1 9.5 4.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KFO96562.1 - 1.9 8.8 8.3 4.3 7.7 5.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BEN PF10523.4 KFO96563.1 - 1.7e-72 239.4 5.4 1.1e-18 67.0 0.1 4.6 4 0 0 4 4 4 4 BEN domain DUF1826 PF08856.6 KFO96563.1 - 0.094 12.4 0.4 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) FAA_hydrolase PF01557.13 KFO96565.1 - 1.7e-21 76.7 0.0 2.1e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family polyprenyl_synt PF00348.12 KFO96566.1 - 4.1e-14 52.0 0.1 6.7e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase VirK PF06903.7 KFO96566.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 VirK protein Yae1_N PF09811.4 KFO96567.1 - 1.5e-11 43.6 32.1 14 5.2 22.3 3.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal SOBP PF15279.1 KFO96568.1 - 4.3e-78 263.7 36.3 4.3e-78 263.7 25.2 3.3 3 0 0 3 3 3 1 Sine oculis-binding protein zf-FCS PF06467.9 KFO96568.1 - 0.027 14.1 19.6 0.062 12.9 2.0 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF3588 PF12140.3 KFO96569.1 - 2.6e-43 146.8 0.8 3.8e-43 146.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 KFO96569.1 - 3.3e-14 52.7 0.1 5.4e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFO96569.1 - 0.00031 20.5 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFO96569.1 - 0.0058 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Sec63 PF02889.11 KFO96570.1 - 6.6e-52 176.6 5.4 6.5e-44 150.4 0.8 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 KFO96570.1 - 3.3e-19 68.3 0.1 9.2e-19 66.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TAN PF11640.3 KFO96570.1 - 0.98 9.1 4.6 3.9 7.2 1.2 2.5 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair PglZ PF08665.7 KFO96570.1 - 1.3 8.6 4.8 0.29 10.7 0.5 1.8 2 0 0 2 2 2 0 PglZ domain OSTMP1 PF09777.4 KFO96571.1 - 1.1e-77 260.3 4.9 1.3e-77 260.1 3.4 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor CECR6_TMEM121 PF14997.1 KFO96571.1 - 0.00054 19.6 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 CECR6/TMEM121 family Hormone_recep PF00104.25 KFO96572.1 - 3.2e-33 114.5 0.1 5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO96572.1 - 4.8e-29 100.3 13.9 1.7e-28 98.6 9.5 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) PX PF00787.19 KFO96573.1 - 5.2e-22 77.7 0.2 5.7e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 PX domain RdRP_1 PF00680.15 KFO96573.1 - 0.038 12.2 0.0 0.045 11.9 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase AFG1_ATPase PF03969.11 KFO96574.1 - 2e-110 368.9 1.6 6.4e-106 354.2 0.3 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KFO96574.1 - 8.6e-06 25.8 0.1 0.0029 17.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 KFO96574.1 - 5.2e-05 23.4 0.2 0.0004 20.5 0.0 2.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 KFO96574.1 - 0.00037 20.2 2.9 0.74 9.4 0.3 3.5 3 1 0 3 3 3 2 Bacterial dnaA protein AAA_22 PF13401.1 KFO96574.1 - 0.00096 19.2 0.1 0.0049 16.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KFO96574.1 - 0.0019 17.9 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain UvrD-helicase PF00580.16 KFO96574.1 - 0.003 16.9 0.1 0.027 13.7 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 KFO96574.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 KFO96574.1 - 0.076 12.6 0.2 0.46 10.1 0.1 2.3 2 1 0 2 2 2 0 Archaeal ATPase PA26 PF04636.8 KFO96575.1 - 2.7e-220 731.7 2.1 3.1e-220 731.5 1.4 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.15 KFO96575.1 - 0.00074 19.3 0.0 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Cep57_CLD PF14073.1 KFO96576.1 - 6e-60 202.0 35.1 6e-60 202.0 24.3 2.5 3 0 0 3 3 3 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.8 KFO96576.1 - 6.7e-19 67.6 2.0 6.7e-19 67.6 1.4 4.2 2 1 2 4 4 4 1 Centrosome microtubule-binding domain of Cep57 DUF2522 PF10747.4 KFO96576.1 - 0.096 12.7 15.1 0.34 10.9 4.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2522) MGC-24 PF05283.6 KFO96577.1 - 2.6e-27 95.8 33.6 2.7e-26 92.5 23.3 1.9 1 1 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) AJAP1_PANP_C PF15298.1 KFO96577.1 - 0.041 13.7 12.5 0.052 13.4 8.6 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF2207 PF09972.4 KFO96577.1 - 0.063 11.8 0.2 0.068 11.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pex14_N PF04695.8 KFO96577.1 - 6.1 6.8 8.0 23 5.0 5.5 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pro_isomerase PF00160.16 KFO96578.1 - 5.3e-38 130.6 0.0 5.8e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADK PF00406.17 KFO96579.1 - 1.1e-19 70.7 0.0 1.9e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KFO96579.1 - 4.7e-10 40.3 0.0 1.4e-09 38.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain YHS PF04945.8 KFO96579.1 - 6.7e-08 32.2 0.9 0.005 16.6 0.0 3.0 3 0 0 3 3 3 2 YHS domain AAA_18 PF13238.1 KFO96579.1 - 9.2e-05 22.7 0.3 0.00085 19.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF3508 PF12018.3 KFO96579.1 - 0.00025 20.1 0.4 0.003 16.5 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3508) AAA_33 PF13671.1 KFO96579.1 - 0.00038 20.3 0.1 0.0025 17.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFO96579.1 - 0.0099 15.8 0.0 0.034 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFO96579.1 - 0.019 14.8 0.1 0.071 13.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFO96579.1 - 0.032 14.3 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFO96579.1 - 0.23 11.6 0.8 0.77 9.9 0.0 2.3 2 1 0 2 2 2 0 RNA helicase ADK PF00406.17 KFO96580.1 - 1.3e-13 51.0 0.1 1.2e-08 35.0 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KFO96580.1 - 7.7e-08 33.1 0.1 3.8e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFO96580.1 - 4.6e-06 26.9 0.1 3.6e-05 24.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain YHS PF04945.8 KFO96580.1 - 7.5e-05 22.4 3.3 9.8e-05 22.1 1.1 2.1 2 0 0 2 2 2 1 YHS domain AAA_28 PF13521.1 KFO96580.1 - 0.00016 21.6 0.0 0.00041 20.3 0.0 1.7 2 1 0 2 2 2 1 AAA domain DUF3508 PF12018.3 KFO96580.1 - 0.00035 19.6 2.5 0.00042 19.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3508) AAA_33 PF13671.1 KFO96580.1 - 0.00039 20.2 0.0 0.001 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KFO96580.1 - 0.00063 19.6 0.0 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase NACHT PF05729.7 KFO96580.1 - 0.001 18.7 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 KFO96580.1 - 0.001 18.2 0.0 0.002 17.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 KFO96580.1 - 0.0022 17.9 0.2 0.034 14.0 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 KFO96580.1 - 0.0031 17.7 0.0 0.0048 17.1 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 KFO96580.1 - 0.0067 15.8 0.5 2.9 7.2 0.0 2.5 2 0 0 2 2 2 2 Thymidylate kinase ABC_tran PF00005.22 KFO96580.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KFO96580.1 - 0.024 14.6 0.3 0.11 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 KFO96580.1 - 0.029 13.0 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit UPF0079 PF02367.12 KFO96580.1 - 0.04 13.5 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KFO96580.1 - 0.04 13.3 0.1 0.14 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFO96580.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KFO96580.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KFO96580.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFO96580.1 - 0.12 12.5 0.1 0.3 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain ADK PF00406.17 KFO96581.1 - 2.6e-23 82.5 0.2 3.1e-20 72.5 0.0 2.5 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.1 KFO96581.1 - 7.3e-12 46.1 9.3 0.00011 22.9 0.0 4.0 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.1 KFO96581.1 - 8.7e-11 42.2 8.7 1.8e-06 28.2 3.2 3.3 2 1 1 3 3 2 2 AAA domain AAA PF00004.24 KFO96581.1 - 4.5e-07 30.1 0.1 0.023 14.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFO96581.1 - 9.2e-06 25.5 0.0 0.0048 16.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFO96581.1 - 1.4e-05 24.7 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 KFO96581.1 - 5.8e-05 23.2 0.0 0.071 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFO96581.1 - 7.3e-05 22.8 0.1 0.051 13.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 KFO96581.1 - 0.00011 22.5 1.8 0.31 11.3 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.1 KFO96581.1 - 0.00025 20.7 0.1 0.16 11.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KFO96581.1 - 0.00051 19.7 0.1 0.0028 17.3 0.1 2.1 2 0 0 2 2 2 1 NACHT domain Herpes_Helicase PF02689.9 KFO96581.1 - 0.00085 17.1 0.4 0.003 15.3 0.0 1.8 2 0 0 2 2 2 1 Helicase RNA_helicase PF00910.17 KFO96581.1 - 0.00099 19.2 0.0 0.83 9.8 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 KFO96581.1 - 0.001 18.6 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_5 PF07728.9 KFO96581.1 - 0.0011 18.7 0.0 0.051 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFO96581.1 - 0.0012 18.7 0.0 2.3 8.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFO96581.1 - 0.0012 17.9 0.0 0.1 11.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin RuvB_N PF05496.7 KFO96581.1 - 0.0018 17.3 0.0 0.25 10.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 KFO96581.1 - 0.0023 17.8 3.9 0.14 12.0 2.3 3.1 2 1 0 2 2 2 1 Shikimate kinase KTI12 PF08433.5 KFO96581.1 - 0.0026 17.0 5.7 0.67 9.0 2.0 2.7 2 1 0 2 2 2 2 Chromatin associated protein KTI12 AAA_28 PF13521.1 KFO96581.1 - 0.0034 17.3 8.9 0.38 10.6 0.0 3.4 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 KFO96581.1 - 0.0034 17.0 0.1 3 7.5 0.0 2.3 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.18 KFO96581.1 - 0.0061 16.5 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 KFO96581.1 - 0.0062 16.1 0.0 0.55 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNase_H2_suC PF08615.6 KFO96581.1 - 0.0076 16.0 0.9 0.011 15.5 0.6 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) cobW PF02492.14 KFO96581.1 - 0.015 14.7 0.0 0.42 10.0 0.0 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 KFO96581.1 - 0.017 14.4 7.6 0.37 10.1 0.1 3.6 3 1 0 3 3 3 0 Thymidylate kinase AAA_25 PF13481.1 KFO96581.1 - 0.029 13.7 0.1 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFO96581.1 - 0.033 13.6 0.0 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_pol_3_Rpc31 PF11705.3 KFO96581.1 - 0.04 13.8 9.0 0.066 13.1 6.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mg_chelatase PF01078.16 KFO96581.1 - 0.049 12.7 0.0 1.6 7.8 0.0 2.5 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.1 KFO96581.1 - 0.075 12.9 1.8 0.52 10.1 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase-like family PduV-EutP PF10662.4 KFO96581.1 - 0.076 12.5 0.0 15 5.0 0.0 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Pox_Ag35 PF03286.9 KFO96581.1 - 0.17 11.3 8.0 0.29 10.6 5.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SRP54 PF00448.17 KFO96581.1 - 0.17 11.3 0.0 8 5.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Miro PF08477.8 KFO96581.1 - 0.3 11.6 2.9 2.9 8.3 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein MobB PF03205.9 KFO96581.1 - 0.34 10.6 4.8 5.3 6.7 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B FAM176 PF14851.1 KFO96581.1 - 0.62 9.7 7.6 1.2 8.7 5.3 1.5 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 KFO96581.1 - 0.71 8.2 13.5 0.99 7.8 9.4 1.2 1 0 0 1 1 1 0 Daxx Family AAA_11 PF13086.1 KFO96581.1 - 0.73 9.3 11.1 30 4.0 0.0 3.1 2 1 0 2 2 2 0 AAA domain BTV_NS2 PF04514.7 KFO96581.1 - 0.94 8.2 8.9 1.5 7.6 6.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CENP-B_dimeris PF09026.5 KFO96581.1 - 1.2 9.4 12.0 2.5 8.4 8.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CobT PF06213.7 KFO96581.1 - 2.2 7.3 12.2 3.8 6.5 8.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 KFO96581.1 - 3.8 5.4 9.8 5.3 4.9 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 KFO96581.1 - 4.9 6.6 16.5 8.2 5.8 11.4 1.2 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.8 KFO96581.1 - 5.3 4.6 16.5 7.4 4.2 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nucleoplasmin PF03066.10 KFO96581.1 - 6.8 6.1 17.9 16 5.0 12.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 KFO96581.1 - 6.8 5.5 7.7 11 4.9 5.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Syja_N PF02383.13 KFO96582.1 - 8.6e-86 287.5 0.0 1.7e-85 286.5 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain 7tm_1 PF00001.16 KFO96583.1 - 1.4e-38 132.4 18.2 1.7e-38 132.2 12.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) WH2 PF02205.15 KFO96584.1 - 1.6e-07 30.6 0.1 2.8e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 WH2 motif WD40 PF00400.27 KFO96585.1 - 5.4e-46 152.8 14.9 7.9e-09 35.0 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFO96585.1 - 0.023 12.8 0.2 2.1 6.3 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Methyltransf_22 PF13383.1 KFO96586.1 - 1.5e-15 57.4 0.1 1.7e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KFO96586.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DAO PF01266.19 KFO96587.1 - 2.9e-20 72.4 0.0 6.4e-20 71.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFO96587.1 - 0.0077 16.6 0.0 0.18 12.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFO96587.1 - 0.02 13.7 0.0 0.5 9.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Spore-coat_CotD PF11122.3 KFO96587.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Inner spore coat protein D UDPG_MGDP_dh_N PF03721.9 KFO96587.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.19 KFO96588.1 - 2e-25 89.3 27.5 2.9e-25 88.7 19.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFO96588.1 - 1.7e-24 86.1 61.3 7.8e-22 77.4 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KFO96589.1 - 3.7e-49 167.2 0.1 4.4e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96589.1 - 2.4e-19 69.4 0.0 3.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFO96589.1 - 0.012 15.3 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFO96589.1 - 0.033 13.2 0.0 0.056 12.4 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFO96589.1 - 0.057 12.1 0.1 0.36 9.5 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase SAM_decarbox PF01536.11 KFO96590.1 - 5e-110 367.2 2.8 5.7e-110 367.0 2.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TFIIIC_sub6 PF10419.4 KFO96591.1 - 3.3e-15 55.2 0.1 5.7e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 TFIIIC subunit Brix PF04427.13 KFO96592.1 - 5.1e-43 146.9 0.3 7.5e-43 146.4 0.2 1.2 1 0 0 1 1 1 1 Brix domain Ion_trans PF00520.26 KFO96593.1 - 4.3e-33 114.2 8.9 4.3e-33 114.2 6.2 1.4 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFO96593.1 - 4.8e-11 42.2 2.8 4.8e-11 42.2 2.0 2.8 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 KFO96593.1 - 0.89 7.8 9.0 0.37 9.1 2.3 2.1 1 1 1 2 2 2 0 Polycystin cation channel RIC3 PF15361.1 KFO96594.1 - 1.6e-14 54.3 0.5 1.8e-14 54.2 0.3 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF4366 PF14283.1 KFO96594.1 - 0.039 13.3 0.1 0.044 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CAP PF00188.21 KFO96595.1 - 8.3e-19 68.2 5.8 1e-18 67.9 4.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Chorein_N PF12624.2 KFO96596.1 - 1.2e-12 47.4 0.1 1.3e-11 44.0 0.0 2.7 3 0 0 3 3 3 1 N-terminal region of Chorein, a TM vesicle-mediated sorter UCH PF00443.24 KFO96597.1 - 8.9e-42 143.0 5.2 1.1e-41 142.8 3.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO96597.1 - 2.8e-22 79.5 8.3 3.8e-22 79.0 5.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tubulin PF00091.20 KFO96598.1 - 6.1e-69 232.1 0.0 7.9e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFO96598.1 - 1e-50 170.9 0.0 1.7e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFO96598.1 - 0.0039 16.6 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KFO96599.1 - 1.1e-68 231.2 0.0 1.5e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFO96599.1 - 4.8e-50 168.8 0.0 8e-50 168.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFO96599.1 - 0.0097 15.3 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pex26 PF07163.7 KFO96600.1 - 7e-90 301.0 0.4 8.5e-90 300.8 0.3 1.0 1 0 0 1 1 1 1 Pex26 protein CH PF00307.26 KFO96601.1 - 2.4e-17 62.9 0.0 8.3e-17 61.2 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFO96601.1 - 2.1e-12 46.5 0.0 6.2e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain LIM PF00412.17 KFO96601.1 - 2.8e-09 36.9 10.7 5.2e-09 36.0 7.4 1.5 1 0 0 1 1 1 1 LIM domain FAD_binding_3 PF01494.14 KFO96601.1 - 1.5e-05 24.2 0.0 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFO96601.1 - 0.00055 18.9 0.1 0.0014 17.6 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFO96601.1 - 0.0006 18.3 0.0 0.0011 17.5 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFO96601.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFO96601.1 - 0.00068 18.5 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFO96601.1 - 0.0019 18.5 0.1 0.0072 16.7 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFO96601.1 - 0.0029 17.6 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFO96601.1 - 0.0031 17.7 0.0 0.0096 16.1 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Thi4 PF01946.12 KFO96601.1 - 0.0035 16.4 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KFO96601.1 - 0.0063 16.5 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFO96601.1 - 0.025 13.5 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KFO96601.1 - 0.039 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BID PF06393.6 KFO96603.1 - 3.6e-49 166.8 3.5 3.9e-49 166.6 2.4 1.0 1 0 0 1 1 1 1 BH3 interacting domain (BID) TAFH PF07531.9 KFO96603.1 - 0.0024 17.4 0.4 0.0053 16.3 0.1 1.6 1 1 0 1 1 1 1 NHR1 homology to TAF Surp PF01805.15 KFO96603.1 - 0.0033 17.0 0.1 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Surp module Phage_int_SAM_2 PF12834.2 KFO96603.1 - 0.0057 17.0 0.1 0.0093 16.3 0.1 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal ARGLU PF15346.1 KFO96603.1 - 0.033 13.9 6.1 0.022 14.5 2.1 1.9 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 DUF1759 PF03564.10 KFO96603.1 - 0.06 13.1 0.9 0.09 12.5 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) YqeY PF09424.5 KFO96603.1 - 0.073 12.9 1.5 0.21 11.4 0.9 1.8 1 1 0 1 1 1 0 Yqey-like protein DUF2573 PF10835.3 KFO96603.1 - 0.097 12.7 0.3 0.31 11.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2573) CotH PF08757.6 KFO96603.1 - 0.14 11.3 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 CotH protein Bcl-2 PF00452.14 KFO96604.1 - 1.3e-11 44.4 0.1 3e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family DUF935 PF06074.7 KFO96604.1 - 0.0076 15.0 0.1 0.01 14.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF935) DUF3770 PF12603.3 KFO96604.1 - 0.0082 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3770) DUF842 PF05811.8 KFO96604.1 - 0.037 13.4 0.1 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF4549 PF15082.1 KFO96604.1 - 0.05 13.2 1.5 0.13 11.9 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) FAST_2 PF08368.7 KFO96604.1 - 0.058 13.7 0.3 0.15 12.4 0.1 1.8 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 2 Adeno_52K PF03052.10 KFO96604.1 - 0.091 11.9 0.3 0.5 9.5 0.0 2.1 2 1 0 2 2 2 0 Adenoviral protein L1 52/55-kDa DUF4047 PF13256.1 KFO96604.1 - 0.29 11.0 2.3 0.38 10.7 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF1722 PF08349.6 KFO96604.1 - 0.35 10.7 2.2 0.77 9.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) vATP-synt_E PF01991.13 KFO96605.1 - 9e-72 240.5 12.7 1.1e-71 240.2 8.8 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit NifW PF03206.9 KFO96605.1 - 0.028 14.5 2.8 0.045 13.8 1.6 1.6 1 1 0 1 1 1 0 Nitrogen fixation protein NifW DUF3724 PF12521.3 KFO96605.1 - 0.07 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) DUF4288 PF14119.1 KFO96605.1 - 0.1 12.7 3.2 1.2 9.2 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DUF4026 PF13218.1 KFO96605.1 - 0.22 10.3 3.8 0.26 10.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) DUF3534 PF12053.3 KFO96605.1 - 0.24 11.2 2.5 4.4 7.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3534) Bromodomain PF00439.20 KFO96606.1 - 1.7e-21 75.8 0.1 3.4e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Ion_trans_2 PF07885.11 KFO96607.1 - 5e-22 77.3 19.3 3.4e-16 58.7 5.7 2.2 2 0 0 2 2 2 2 Ion channel Presenilin PF01080.12 KFO96607.1 - 0.02 13.7 4.8 0.027 13.2 3.3 1.2 1 0 0 1 1 1 0 Presenilin MutS_V PF00488.16 KFO96608.1 - 1.5e-99 332.1 0.1 2.6e-99 331.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFO96608.1 - 1.4e-36 126.1 1.4 1.4e-36 126.1 1.0 2.1 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.12 KFO96608.1 - 9e-22 77.6 0.1 3.3e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KFO96608.1 - 1.5e-20 73.1 3.3 4e-20 71.7 2.3 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 KFO96608.1 - 7e-05 22.8 0.0 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 MutS domain I DUF2935 PF11155.3 KFO96608.1 - 4.8 7.2 9.9 4.1 7.5 0.3 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Thyroglobulin_1 PF00086.13 KFO96609.1 - 1.3e-14 53.2 1.5 1.3e-14 53.2 1.1 2.3 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat Rifin_STEVOR PF02009.11 KFO96609.1 - 0.0053 16.4 1.1 0.0086 15.7 0.8 1.4 1 0 0 1 1 1 1 Rifin/stevor family DAG1 PF05454.6 KFO96609.1 - 0.13 11.4 1.7 0.22 10.6 1.2 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) GCD14 PF08704.5 KFO96610.1 - 4.1e-21 75.5 0.0 1.4e-20 73.8 0.0 1.6 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KFO96610.1 - 8.8e-08 31.8 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFO96610.1 - 2.1e-07 30.7 0.0 3e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KFO96610.1 - 6.1e-07 30.0 0.0 8.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFO96610.1 - 2.2e-06 27.6 0.0 7.7e-06 25.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO96610.1 - 0.00035 20.9 0.0 0.00095 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KFO96610.1 - 0.00036 21.3 0.0 0.00053 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFO96610.1 - 0.002 18.1 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase CmcI PF04989.7 KFO96610.1 - 0.0021 17.3 0.0 0.0045 16.3 0.0 1.5 2 0 0 2 2 2 1 Cephalosporin hydroxylase Methyltransf_25 PF13649.1 KFO96610.1 - 0.0072 16.6 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO96610.1 - 0.0078 15.9 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFO96610.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KFO96610.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 KFO96610.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.12 KFO96610.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DOT1 PF08123.8 KFO96610.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Utp12 PF04003.7 KFO96611.1 - 4.3e-23 81.3 1.2 7.3e-23 80.5 0.8 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 KFO96611.1 - 1.6e-19 68.9 4.0 5.7e-08 32.3 0.3 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat UTP15_C PF09384.5 KFO96611.1 - 0.035 13.7 0.1 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 UTP15 C terminal TRAP_alpha PF03896.11 KFO96611.1 - 6.4 5.6 8.6 11 4.9 6.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Retinal PF15449.1 KFO96612.1 - 0 1362.0 83.2 0 1361.9 57.7 1.0 1 0 0 1 1 1 1 Retinal protein Pkinase_Tyr PF07714.12 KFO96613.1 - 8.4e-89 297.0 0.0 1.1e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO96613.1 - 2.3e-37 128.5 0.0 3.2e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.2 KFO96613.1 - 8.9e-15 54.9 29.2 1.7e-14 54.0 20.2 1.3 1 0 0 1 1 1 1 Glycine rich protein MAM PF00629.18 KFO96613.1 - 4.8e-13 49.1 0.0 8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 MAM domain Kinase-like PF14531.1 KFO96613.1 - 0.0065 15.4 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ank_2 PF12796.2 KFO96616.1 - 3.6e-10 40.0 0.1 2.4e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFO96616.1 - 1.9e-09 37.4 0.2 3.4e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFO96616.1 - 3e-08 33.0 5.1 1.1e-06 28.1 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KFO96616.1 - 6.9e-07 29.6 0.1 0.028 14.9 0.2 3.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO96616.1 - 1.6e-06 27.7 0.1 0.0026 17.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat SOCS_box PF07525.11 KFO96616.1 - 0.0052 16.6 0.8 0.016 15.0 0.6 1.9 1 0 0 1 1 1 1 SOCS box Yippee-Mis18 PF03226.9 KFO96617.1 - 7.1e-18 64.4 0.2 8e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 KFO96617.1 - 0.0046 16.9 0.1 0.072 13.1 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.10 KFO96617.1 - 0.0068 16.0 0.7 0.034 13.8 0.3 2.0 1 1 1 2 2 2 1 Recombination endonuclease VII SelR PF01641.13 KFO96617.1 - 0.011 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 SelR domain RIG-I_C-RD PF11648.3 KFO96617.1 - 0.016 15.0 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I HECT_2 PF09814.4 KFO96617.1 - 0.042 12.5 0.8 0.09 11.4 0.0 1.7 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Mut7-C PF01927.11 KFO96617.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain Sgf11 PF08209.6 KFO96617.1 - 0.31 10.3 3.0 6 6.2 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Rpr2 PF04032.11 KFO96617.1 - 0.68 9.8 2.8 4.3 7.2 0.2 2.2 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Lbh PF15317.1 KFO96619.1 - 2e-37 127.3 1.8 2.2e-37 127.2 1.2 1.0 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein Acyltransferase PF01553.16 KFO96620.1 - 6.9e-22 77.3 0.0 1.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Glycos_transf_2 PF00535.21 KFO96621.1 - 7.1e-20 71.3 0.0 1.1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFO96621.1 - 2.6e-17 62.9 3.0 5.8e-17 61.8 2.1 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 KFO96621.1 - 1.1e-06 27.9 0.0 2.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 KFO96621.1 - 5.9e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFO96621.1 - 0.0066 15.5 0.0 0.052 12.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 GlcNAc PF11397.3 KFO96621.1 - 0.07 12.2 0.4 0.27 10.2 0.0 2.1 2 1 0 2 2 2 0 Glycosyltransferase (GlcNAc) Dynamin_N PF00350.18 KFO96622.1 - 2.3e-19 69.8 0.0 1.2e-18 67.4 0.0 2.1 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 KFO96622.1 - 2.8e-19 68.7 0.2 1.6e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 KFO96622.1 - 1e-09 38.3 0.0 4.8e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFO96622.1 - 0.00018 21.9 0.0 0.0097 16.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFO96622.1 - 0.0009 18.7 0.2 0.04 13.3 0.4 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EF-hand_1 PF00036.27 KFO96622.1 - 0.00099 18.2 0.6 0.0033 16.6 0.1 2.2 2 0 0 2 2 1 1 EF hand FeoB_N PF02421.13 KFO96622.1 - 0.009 15.3 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 KFO96622.1 - 0.011 14.9 0.0 0.067 12.2 0.0 2.2 3 0 0 3 3 3 0 AIG1 family AAA_28 PF13521.1 KFO96622.1 - 0.012 15.6 0.0 0.091 12.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.7 KFO96622.1 - 0.013 14.6 0.1 0.23 10.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region UPF0278 PF08745.6 KFO96622.1 - 0.022 14.0 0.2 0.046 12.9 0.0 1.5 2 0 0 2 2 2 0 UPF0278 family AAA_22 PF13401.1 KFO96622.1 - 0.031 14.4 0.0 0.13 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KFO96622.1 - 0.036 13.5 0.0 6 6.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain EF-hand_7 PF13499.1 KFO96622.1 - 0.067 13.3 0.1 0.23 11.6 0.0 1.9 2 0 0 2 2 1 0 EF-hand domain pair MobB PF03205.9 KFO96622.1 - 0.083 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Spc7 PF08317.6 KFO96622.1 - 0.094 11.3 4.7 0.027 13.1 1.2 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_16 PF13191.1 KFO96622.1 - 0.13 12.2 0.2 5.5 6.9 0.0 3.0 2 1 0 3 3 3 0 AAA ATPase domain UPF0079 PF02367.12 KFO96622.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 KFO96622.1 - 0.14 11.6 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family EF-hand_8 PF13833.1 KFO96622.1 - 0.37 10.4 2.2 0.49 10.0 0.3 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 KFO96622.1 - 2.7 7.4 5.0 0.57 9.6 0.5 2.2 2 0 0 2 2 2 0 EF hand Ald_Xan_dh_C2 PF02738.13 KFO96623.1 - 1.4e-214 713.4 0.0 2e-214 712.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KFO96623.1 - 4.1e-54 182.5 0.0 6.8e-54 181.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KFO96623.1 - 3.1e-37 127.0 0.5 5.6e-37 126.2 0.4 1.4 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KFO96623.1 - 2e-31 107.9 0.0 4.7e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KFO96623.1 - 8.8e-28 96.0 0.1 1.9e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KFO96623.1 - 4.4e-07 29.5 1.1 4.4e-07 29.5 0.8 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain rve PF00665.21 KFO96624.1 - 1.6e-26 92.8 0.1 2.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 KFO96624.1 - 6.4e-12 44.7 0.1 1.3e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.19 KFO96624.1 - 1.1e-10 41.9 0.0 2.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNase H DDE_Tnp_IS240 PF13610.1 KFO96624.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.1 KFO96624.1 - 0.078 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain FbpA PF05833.6 KFO96625.1 - 2e-38 132.1 17.9 2e-38 132.1 12.4 2.8 3 0 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 KFO96625.1 - 1.4e-29 101.9 0.1 1.4e-29 101.9 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KFO96625.1 - 8.2e-25 86.5 0.0 4.9e-24 84.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Kelch_4 PF13418.1 KFO96626.1 - 1.2e-31 108.1 23.1 4.8e-10 39.0 0.1 7.8 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KFO96626.1 - 7.7e-31 105.5 14.3 2.7e-07 30.5 0.1 8.0 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO96626.1 - 1.6e-23 82.1 14.2 3.5e-05 23.6 0.0 7.4 7 2 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFO96626.1 - 7.3e-22 76.5 15.1 3.3e-06 27.0 0.0 7.0 6 1 1 7 7 7 3 Kelch motif Kelch_1 PF01344.20 KFO96626.1 - 2.1e-17 62.4 14.6 0.0023 17.4 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KFO96626.1 - 4.4e-14 51.6 19.3 0.00031 20.3 0.0 6.9 6 1 0 6 6 6 5 Kelch motif Rax2 PF12768.2 KFO96626.1 - 0.012 14.7 0.1 0.04 13.1 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Kelch_3 PF13415.1 KFO96627.1 - 3.5e-32 109.8 18.2 3e-07 30.4 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFO96627.1 - 4.4e-32 109.6 20.1 3.1e-09 36.4 0.4 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KFO96627.1 - 3.8e-26 90.1 19.3 3.7e-07 30.0 0.1 6.7 4 1 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFO96627.1 - 3.5e-19 68.3 4.3 0.00071 19.4 0.1 5.9 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 KFO96627.1 - 1.7e-18 65.8 10.0 4.4e-05 22.9 0.3 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KFO96627.1 - 2.3e-17 62.0 18.5 2.3e-06 27.1 0.0 6.1 5 2 1 6 6 6 5 Kelch motif DNA_pol_E_B PF04042.11 KFO96628.1 - 5.6e-52 176.0 1.4 8.6e-52 175.4 1.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 KFO96628.1 - 1.7e-18 66.3 2.1 3.5e-18 65.2 1.5 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal MGAT2 PF05060.9 KFO96630.1 - 1.2e-128 429.0 1.4 1.3e-128 428.8 1.0 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) LRR_4 PF12799.2 KFO96631.1 - 3.4e-20 71.2 8.7 1.5e-09 37.2 0.5 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO96631.1 - 6.5e-15 54.6 14.3 3.1e-08 33.2 2.5 3.3 3 0 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 KFO96631.1 - 4.7e-12 44.0 11.0 0.016 15.2 0.1 7.5 7 0 0 7 7 7 3 Leucine rich repeat LRR_1 PF00560.28 KFO96631.1 - 1.5e-11 42.6 17.1 0.021 14.7 0.0 7.0 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.1 KFO96631.1 - 2.1e-05 24.0 14.0 0.44 10.7 0.4 6.0 5 1 2 7 7 7 3 Leucine Rich repeat Ribosomal_S14 PF00253.16 KFO96632.1 - 3.3e-19 67.9 4.5 3.6e-19 67.8 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 KFO96632.1 - 0.056 13.2 0.4 0.07 12.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Rsm1 PF08600.5 KFO96632.1 - 3.5 7.5 4.8 11 5.9 0.2 2.0 1 1 1 2 2 2 0 Rsm1-like 7tm_1 PF00001.16 KFO96633.1 - 1.5e-09 37.4 0.3 2.8e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Trypan_PARP PF05887.6 KFO96634.1 - 0.0021 17.9 97.0 0.7 9.7 23.8 3.6 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) RasGAP PF00616.14 KFO96636.1 - 9.1e-51 172.3 1.7 9.4e-50 169.0 0.0 2.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KFO96636.1 - 7.1e-41 139.2 12.0 9e-41 138.8 8.7 3.9 4 0 0 4 4 4 2 RasGAP C-terminus IQ PF00612.22 KFO96636.1 - 2.6e-18 63.8 20.8 1.1e-05 24.6 0.4 5.3 5 0 0 5 5 5 4 IQ calmodulin-binding motif CH PF00307.26 KFO96636.1 - 1.1e-14 54.4 0.0 6.4e-14 51.8 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain WW PF00397.21 KFO96636.1 - 0.037 13.9 5.2 0.07 13.0 3.6 1.5 1 0 0 1 1 1 0 WW domain Spc97_Spc98 PF04130.8 KFO96637.1 - 1.3e-98 330.7 8.5 2e-98 330.0 5.9 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF383 PF04063.9 KFO96637.1 - 0.074 12.5 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF383) 53-BP1_Tudor PF09038.5 KFO96638.1 - 6.2e-73 242.3 0.3 1.3e-72 241.3 0.2 1.6 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor BRCT PF00533.21 KFO96638.1 - 0.00043 20.3 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.1 KFO96638.1 - 0.0015 18.3 0.0 0.0077 16.0 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) His_Phos_2 PF00328.17 KFO96640.1 - 1.4e-108 363.3 0.2 1.8e-108 362.9 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KFO96640.1 - 0.0057 16.1 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 KFO96640.1 - 0.0064 16.6 0.0 0.022 14.8 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ATP-gua_Ptrans PF00217.14 KFO96641.1 - 3.8e-103 344.0 0.0 4.5e-103 343.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 KFO96641.1 - 4.4e-34 116.4 0.0 6.9e-34 115.8 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Thioredoxin PF00085.15 KFO96642.1 - 1.8e-58 194.6 0.2 2.9e-32 110.4 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KFO96642.1 - 1.6e-42 145.3 0.1 2.6e-35 121.9 0.2 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFO96642.1 - 6e-11 42.5 0.9 3e-06 27.3 0.1 4.0 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFO96642.1 - 2.6e-06 27.4 0.0 0.00063 19.8 0.0 3.6 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFO96642.1 - 7.8e-06 25.8 0.0 0.00017 21.5 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.1 KFO96642.1 - 0.0013 18.7 0.1 0.21 11.5 0.0 3.6 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.1 KFO96642.1 - 0.0063 16.3 0.1 0.38 10.6 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.16 KFO96642.1 - 0.055 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA family Serinc PF03348.10 KFO96643.1 - 4.6e-119 397.9 19.5 5.5e-119 397.6 13.5 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Prp19_bind PF06991.6 KFO96645.1 - 5e-130 432.7 37.2 5e-130 432.7 25.8 2.2 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Ebola_NP PF05505.7 KFO96645.1 - 9.1 4.2 21.0 3 5.8 12.9 1.4 1 1 0 1 1 1 0 Ebola nucleoprotein Glyco_hydro_38 PF01074.17 KFO96646.1 - 2.6e-96 322.1 1.3 3.6e-96 321.6 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFO96646.1 - 1.6e-72 244.7 0.0 1.3e-71 241.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFO96646.1 - 8.4e-24 83.5 0.0 1.8e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain UNC45-central PF11701.3 KFO96647.1 - 9.6e-44 148.7 15.8 2.2e-41 141.1 0.2 4.9 4 1 1 5 5 5 3 Myosin-binding striated muscle assembly central TPR_11 PF13414.1 KFO96647.1 - 4.2e-07 29.5 0.0 1.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KFO96647.1 - 6.8e-06 25.6 0.3 0.00038 20.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_2 PF13646.1 KFO96647.1 - 6.8e-06 26.2 16.1 0.06 13.6 0.0 6.9 5 3 2 8 8 8 3 HEAT repeats TPR_1 PF00515.23 KFO96647.1 - 0.00041 19.8 0.1 0.082 12.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO96647.1 - 0.0036 17.9 0.4 0.013 16.1 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFO96647.1 - 0.0057 16.4 0.5 0.018 14.9 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFO96647.1 - 0.013 15.5 0.0 0.29 11.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96647.1 - 0.015 15.8 3.0 0.025 15.1 0.1 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat Arm PF00514.18 KFO96647.1 - 0.022 14.5 10.7 9.2 6.2 0.0 7.7 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat TPR_6 PF13174.1 KFO96647.1 - 0.026 14.9 0.7 0.74 10.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_N PF14852.1 KFO96647.1 - 0.028 13.7 0.1 20 4.5 0.0 4.1 4 0 0 4 4 4 0 Fis1 N-terminal tetratricopeptide repeat TPR_8 PF13181.1 KFO96647.1 - 0.059 13.1 0.6 0.31 10.9 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat RCC1 PF00415.13 KFO96648.1 - 1.4e-24 86.0 0.7 3e-12 46.5 0.2 3.1 2 1 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFO96648.1 - 2e-13 49.5 7.5 7.8e-10 38.1 1.1 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat MAP65_ASE1 PF03999.7 KFO96649.1 - 1.7e-137 459.6 25.4 2.2e-137 459.2 17.6 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Sec1 PF00995.18 KFO96650.1 - 5.5e-86 289.4 0.0 6.7e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TTL PF03133.10 KFO96651.1 - 4.9e-89 298.1 0.1 9e-89 297.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFO96651.1 - 2.9e-07 29.5 0.2 3.9e-05 22.5 0.0 3.0 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 KFO96651.1 - 0.0031 17.4 0.0 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KFO96651.1 - 0.013 14.9 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain HCaRG PF07258.9 KFO96651.1 - 0.028 13.9 0.5 0.049 13.1 0.3 1.4 1 0 0 1 1 1 0 HCaRG protein Dala_Dala_lig_C PF07478.8 KFO96651.1 - 0.039 13.3 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 KFO96651.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain EF-hand_7 PF13499.1 KFO96652.1 - 3.7e-12 46.1 7.4 7.7e-12 45.1 2.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFO96652.1 - 8.7e-12 43.4 6.7 3e-05 23.0 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFO96652.1 - 6.1e-11 41.2 5.5 6.5e-05 22.4 0.4 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFO96652.1 - 6.7e-10 37.8 6.1 9.6e-06 24.7 0.6 3.1 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFO96652.1 - 5.8e-08 32.2 10.1 0.001 18.6 0.5 2.8 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO96652.1 - 1.1e-05 25.3 0.9 2.1e-05 24.4 0.6 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFO96652.1 - 0.025 14.3 6.2 0.24 11.1 0.2 2.8 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFO96652.1 - 0.069 13.0 1.2 0.35 10.8 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain Gal4_dimer PF03902.8 KFO96652.1 - 0.096 12.6 2.6 0.19 11.7 0.3 2.3 1 1 1 2 2 2 0 Gal4-like dimerisation domain EF-hand_10 PF14788.1 KFO96652.1 - 2.7 7.7 5.0 4.6 6.9 0.3 2.9 2 2 1 3 3 3 0 EF hand DUF3944 PF13099.1 KFO96652.1 - 6.9 6.2 6.8 0.38 10.2 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3944) PX PF00787.19 KFO96653.1 - 1.1e-19 70.3 0.1 2.3e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 PX domain RA PF00788.18 KFO96653.1 - 9.4e-12 45.2 0.2 3.5e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain USP7_C2 PF14533.1 KFO96653.1 - 0.0082 15.5 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal FERM_N PF09379.5 KFO96653.1 - 0.032 14.2 0.1 0.11 12.6 0.0 2.1 1 1 0 1 1 1 0 FERM N-terminal domain GCOM2 PF15328.1 KFO96654.1 - 7.3e-08 32.4 3.9 8.9e-08 32.1 2.7 1.1 1 0 0 1 1 1 1 Putative GRINL1B complex locus protein 2 Gp58 PF07902.6 KFO96654.1 - 0.001 17.3 4.3 0.0012 17.2 3.0 1.0 1 0 0 1 1 1 1 gp58-like protein Tropomyosin_1 PF12718.2 KFO96654.1 - 0.0016 18.2 17.4 0.0032 17.3 12.1 1.5 1 1 0 1 1 1 1 Tropomyosin like bZIP_1 PF00170.16 KFO96654.1 - 0.004 17.0 16.9 0.023 14.6 0.3 3.5 3 1 0 3 3 3 2 bZIP transcription factor Prominin PF05478.6 KFO96654.1 - 0.013 13.0 2.7 0.014 12.9 1.9 1.1 1 0 0 1 1 1 0 Prominin SlyX PF04102.7 KFO96654.1 - 0.028 14.7 17.4 0.17 12.3 4.8 3.1 2 1 1 3 3 3 0 SlyX CENP-F_leu_zip PF10473.4 KFO96654.1 - 0.03 14.1 20.4 0.11 12.3 8.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_env PF01673.13 KFO96654.1 - 0.04 12.4 0.7 0.15 10.6 0.0 1.8 1 1 1 2 2 2 0 Herpesvirus putative major envelope glycoprotein DUF445 PF04286.7 KFO96654.1 - 0.047 13.2 7.1 0.054 13.0 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Reo_sigmaC PF04582.7 KFO96654.1 - 0.054 12.6 0.7 0.058 12.5 0.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 KFO96654.1 - 0.069 13.0 16.7 0.4 10.5 9.0 2.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NYD-SP28 PF14772.1 KFO96654.1 - 0.072 13.1 11.6 3.5 7.7 7.8 2.4 1 1 0 1 1 1 0 Sperm tail COG5 PF10392.4 KFO96654.1 - 0.075 12.9 5.0 0.098 12.6 3.5 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 AAA_32 PF13654.1 KFO96654.1 - 0.077 11.6 7.6 0.087 11.4 5.3 1.1 1 0 0 1 1 1 0 AAA domain HAUS5 PF14817.1 KFO96654.1 - 0.087 11.3 12.6 0.075 11.5 7.9 1.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 DUF2051 PF09738.4 KFO96654.1 - 0.092 12.0 11.2 0.017 14.4 5.0 1.8 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) CCDC155 PF14662.1 KFO96654.1 - 0.11 12.0 17.4 0.11 12.1 11.1 1.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Jnk-SapK_ap_N PF09744.4 KFO96654.1 - 0.14 12.1 17.0 2.2 8.2 9.8 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fmp27_WPPW PF10359.4 KFO96654.1 - 0.14 10.5 6.5 0.17 10.2 4.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2265 PF10023.4 KFO96654.1 - 0.15 11.1 2.7 0.19 10.8 1.9 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) BLOC1_2 PF10046.4 KFO96654.1 - 0.17 12.0 7.9 0.25 11.5 1.5 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_HBL PF05791.6 KFO96654.1 - 0.2 11.0 5.3 0.17 11.2 2.5 1.7 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) COG2 PF06148.6 KFO96654.1 - 0.25 11.2 10.6 0.55 10.1 6.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.1 KFO96654.1 - 0.25 10.2 3.5 0.3 9.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RasGAP_C PF03836.10 KFO96654.1 - 0.26 10.9 9.5 0.4 10.3 2.6 2.2 1 1 1 2 2 2 0 RasGAP C-terminus TBPIP PF07106.8 KFO96654.1 - 0.28 10.7 13.7 0.17 11.4 8.3 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ubiquitin PF00240.18 KFO96654.1 - 0.35 10.3 4.4 0.16 11.4 0.6 2.2 2 1 0 2 2 2 0 Ubiquitin family DUF1664 PF07889.7 KFO96654.1 - 0.36 10.6 8.6 0.27 11.0 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HalX PF08663.5 KFO96654.1 - 0.41 10.6 2.9 2.2 8.3 1.1 2.5 2 0 0 2 2 2 0 HalX domain Spc7 PF08317.6 KFO96654.1 - 0.44 9.1 12.9 0.6 8.7 8.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMCO5 PF14992.1 KFO96654.1 - 0.49 9.4 13.8 0.67 9.0 9.5 1.2 1 0 0 1 1 1 0 TMCO5 family ACCA PF03255.9 KFO96654.1 - 0.5 9.9 6.1 3 7.3 4.3 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CASP_C PF08172.7 KFO96654.1 - 0.51 9.3 8.0 1.9 7.4 1.6 2.1 1 1 1 2 2 2 0 CASP C terminal Seadorna_VP6 PF07407.6 KFO96654.1 - 0.65 8.6 2.7 0.71 8.5 1.9 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein CorA PF01544.13 KFO96654.1 - 0.67 8.9 3.7 0.81 8.6 2.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CCDC-167 PF15188.1 KFO96654.1 - 0.77 9.7 11.7 0.61 10.0 2.0 2.8 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.14 KFO96654.1 - 0.79 7.5 6.8 0.9 7.3 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 KFO96654.1 - 0.87 9.5 18.4 0.098 12.6 7.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) AKNA PF12443.3 KFO96654.1 - 0.99 9.4 8.4 0.47 10.5 3.3 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor DivIC PF04977.10 KFO96654.1 - 1.1 8.8 17.9 2.8 7.4 1.5 3.3 1 1 2 3 3 3 0 Septum formation initiator TMPIT PF07851.8 KFO96654.1 - 1.1 8.2 5.4 1.4 7.8 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4559 PF15112.1 KFO96654.1 - 1.1 8.3 8.0 1.4 8.0 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3740 PF12548.3 KFO96654.1 - 1.2 9.4 7.5 0.33 11.2 1.8 2.2 1 1 1 2 2 2 0 Sulfatase protein ATG16 PF08614.6 KFO96654.1 - 1.3 8.7 15.6 1.8 8.3 9.8 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.10 KFO96654.1 - 1.4 8.8 18.3 0.21 11.4 0.6 3.5 3 1 0 3 3 3 0 Basic region leucine zipper TSC22 PF01166.13 KFO96654.1 - 1.6 8.7 10.7 1.4 8.9 0.4 3.3 1 1 2 3 3 3 0 TSC-22/dip/bun family Fib_alpha PF08702.5 KFO96654.1 - 1.7 8.7 10.9 8.9 6.4 4.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 KFO96654.1 - 2.3 6.5 12.4 4.1 5.7 8.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KFO96654.1 - 2.4 7.7 18.6 6.3 6.3 12.9 1.7 1 1 0 1 1 1 0 IncA protein DUF3450 PF11932.3 KFO96654.1 - 2.4 7.3 11.4 3 7.0 7.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.17 KFO96654.1 - 3.1 7.8 14.7 1.9 8.5 3.1 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-Q PF13094.1 KFO96654.1 - 3.5 7.6 16.4 1.7 8.6 8.2 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin_2 PF01920.15 KFO96654.1 - 4.1 7.2 18.4 1.3 8.8 3.3 3.0 1 1 2 3 3 3 0 Prefoldin subunit Uds1 PF15456.1 KFO96654.1 - 4.1 7.4 13.5 0.99 9.4 4.9 2.1 1 1 2 3 3 3 0 Up-regulated During Septation Med9 PF07544.8 KFO96654.1 - 5.1 6.8 11.2 8.4 6.2 6.4 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF641 PF04859.7 KFO96654.1 - 5.2 6.8 13.0 6 6.6 3.9 2.6 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) GrpE PF01025.14 KFO96654.1 - 5.9 6.4 13.1 1.2 8.7 2.5 2.6 1 1 2 3 3 3 0 GrpE Snapin_Pallidin PF14712.1 KFO96654.1 - 6.2 7.1 14.5 16 5.9 4.4 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Atg14 PF10186.4 KFO96654.1 - 6.5 5.6 16.7 14 4.5 0.3 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Kinesin-relat_1 PF12711.2 KFO96654.1 - 7.3 7.0 13.8 0.71 10.3 4.8 2.5 1 1 1 2 2 2 0 Kinesin motor Mnd1 PF03962.10 KFO96654.1 - 8.8 5.9 14.3 4 7.0 6.4 1.9 1 1 1 2 2 2 0 Mnd1 family Fzo_mitofusin PF04799.8 KFO96654.1 - 8.9 5.6 9.7 2.2 7.6 3.1 2.2 1 1 2 3 3 3 0 fzo-like conserved region DUF972 PF06156.8 KFO96654.1 - 9.8 6.5 14.9 5.7 7.3 2.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Proteasome PF00227.21 KFO96655.1 - 3.6e-27 94.8 0.0 4.2e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 KFO96655.1 - 0.071 12.7 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain zf-C2H2_4 PF13894.1 KFO96656.1 - 3e-06 27.1 59.7 0.0035 17.5 0.4 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-Di19 PF05605.7 KFO96656.1 - 1.1e-05 25.4 37.9 0.11 12.6 0.3 5.3 4 1 1 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFO96656.1 - 0.0001 22.4 62.3 0.13 12.6 0.5 7.6 7 1 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFO96656.1 - 0.0021 18.1 32.1 0.027 14.5 0.5 6.5 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFO96656.1 - 0.037 14.3 0.3 0.037 14.3 0.2 7.5 9 1 0 9 9 9 0 Zinc-finger double domain PyrI_C PF02748.10 KFO96656.1 - 0.05 13.0 8.6 0.061 12.7 0.1 4.2 4 1 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rubredoxin PF00301.15 KFO96656.1 - 0.34 10.8 19.4 0.94 9.4 0.0 6.1 6 1 0 6 6 6 0 Rubredoxin DUF2757 PF10955.3 KFO96656.1 - 0.52 10.5 7.6 0.5 10.6 2.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) zinc_ribbon_4 PF13717.1 KFO96656.1 - 0.68 9.6 0.1 0.68 9.6 0.0 5.7 7 0 0 7 7 7 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 KFO96656.1 - 3.3 7.8 37.6 2.5 8.2 0.8 5.9 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) SBP56 PF05694.6 KFO96657.1 - 3.2e-212 705.0 0.0 3.6e-212 704.9 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KFO96657.1 - 3.3e-05 23.1 0.0 0.00062 18.9 0.0 2.4 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.6 KFO96658.1 - 5.3e-111 371.3 0.0 3.4e-72 243.4 0.0 2.0 2 0 0 2 2 2 2 56kDa selenium binding protein (SBP56) RFX_DNA_binding PF02257.10 KFO96659.1 - 1.3e-31 108.5 0.1 1.5e-30 105.1 0.0 2.0 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFO96659.1 - 0.00065 19.9 0.0 0.00097 19.3 0.0 1.3 1 0 0 1 1 1 1 Poxvirus D5 protein-like PI3_PI4_kinase PF00454.22 KFO96660.1 - 4.3e-32 111.4 0.3 3.9e-31 108.3 0.2 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 KFO96660.1 - 0.067 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) UIM PF02809.15 KFO96661.1 - 1.5e-05 24.1 1.0 1.5e-05 24.1 0.7 2.5 3 0 0 3 3 3 1 Ubiquitin interaction motif VWA_2 PF13519.1 KFO96661.1 - 0.0022 18.1 0.1 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain PIP5K PF01504.13 KFO96662.1 - 2.8e-77 259.2 0.0 3.6e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase YL1 PF05764.8 KFO96663.1 - 3.9e-36 124.8 2.6 5.6e-36 124.3 1.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 KFO96663.1 - 2.8e-13 49.1 0.4 7e-13 47.8 0.1 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain TOM_sub5 PF15178.1 KFO96663.1 - 0.097 12.3 0.7 8.1 6.2 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM5 homolog Tropomodulin PF03250.9 KFO96664.1 - 6.8e-42 142.4 0.3 6.8e-42 142.4 0.2 1.6 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.1 KFO96664.1 - 0.054 13.5 3.0 0.12 12.4 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 KFO96664.1 - 0.33 10.6 2.0 2 8.1 0.2 2.5 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) GHBP PF12772.2 KFO96665.1 - 0.0049 16.3 3.4 0.76 9.1 0.2 2.0 1 1 1 2 2 2 2 Growth hormone receptor binding Lipase3_N PF03893.11 KFO96665.1 - 0.36 10.6 5.2 44 3.9 0.1 3.5 3 0 0 3 3 3 0 Lipase 3 N-terminal region Ank_2 PF12796.2 KFO96666.1 - 8.2e-34 115.8 0.9 1.5e-21 76.4 0.6 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFO96666.1 - 7.1e-33 110.7 1.9 1.6e-10 40.2 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFO96666.1 - 6.3e-25 84.7 0.8 1.3e-07 31.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFO96666.1 - 1.3e-21 76.1 2.2 8.2e-07 29.0 0.1 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO96666.1 - 5.3e-20 71.3 0.9 1e-09 38.6 0.2 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PBD PF00786.23 KFO96667.1 - 0.00083 19.7 0.1 0.0014 19.0 0.1 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain Laminin_II PF06009.7 KFO96668.1 - 0.36 10.5 3.1 1 9.1 0.5 2.4 2 1 0 2 2 2 0 Laminin Domain II PAS_11 PF14598.1 KFO96669.1 - 1.7e-24 85.9 0.4 1.6e-20 73.1 0.2 2.8 2 1 0 2 2 2 2 PAS domain PAS_3 PF08447.6 KFO96669.1 - 1.2e-22 79.8 0.0 1.6e-16 60.1 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KFO96669.1 - 8.1e-21 73.9 0.1 5.5e-13 48.7 0.0 2.8 3 0 0 3 3 3 2 PAS fold HLH PF00010.21 KFO96669.1 - 1.4e-12 47.1 2.1 1.8e-12 46.7 0.7 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFO96669.1 - 5.2e-08 33.1 0.0 1.8e-06 28.2 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KFO96669.1 - 0.0035 17.3 0.0 0.83 9.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold DUF3067 PF11267.3 KFO96669.1 - 0.036 14.1 0.1 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3067) Peptidase_C1 PF00112.18 KFO96670.1 - 5.3e-24 85.3 2.2 5.6e-24 85.2 1.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFO96670.1 - 2.7e-05 22.8 0.5 3.2e-05 22.6 0.4 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KFO96671.1 - 2.5e-84 282.5 1.3 2.9e-84 282.3 0.9 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFO96671.1 - 4.1e-05 22.3 1.9 0.025 13.1 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.7 KFO96671.1 - 0.00022 21.4 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PINIT PF14324.1 KFO96672.1 - 4.6e-44 149.9 0.2 8.2e-44 149.1 0.2 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFO96672.1 - 1.7e-20 72.2 5.1 4.1e-20 71.0 3.6 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFO96672.1 - 0.00011 21.6 1.4 0.00026 20.4 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KFO96672.1 - 0.0011 18.3 0.1 0.0028 17.1 0.1 1.7 1 0 0 1 1 1 1 SAP domain RNA_pol_Rpc82 PF05645.8 KFO96673.1 - 8.7e-38 130.3 0.0 6e-37 127.5 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KFO96673.1 - 3.9e-09 36.2 4.1 0.00067 19.4 0.4 4.2 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.14 KFO96673.1 - 0.087 12.5 0.4 1 9.1 0.0 3.1 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB RdRP_4 PF02123.11 KFO96673.1 - 0.22 10.2 2.6 0.33 9.6 1.8 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase Mnd1 PF03962.10 KFO96673.1 - 2.3 7.8 15.3 0.066 12.8 5.2 2.5 2 1 0 2 2 2 0 Mnd1 family zf-RING_2 PF13639.1 KFO96674.1 - 2.1e-14 53.0 7.9 2.1e-14 53.0 5.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFO96674.1 - 1.2e-07 31.6 7.0 1.2e-07 31.6 4.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFO96674.1 - 1.2e-07 31.6 5.7 3.3e-07 30.3 4.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFO96674.1 - 3.9e-07 29.6 5.2 3.9e-07 29.6 3.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFO96674.1 - 5.8e-07 29.0 3.0 5.8e-07 29.0 2.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO96674.1 - 8.8e-07 28.4 6.8 8.8e-07 28.4 4.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFO96674.1 - 1.2e-05 25.0 3.9 0.00024 20.8 2.3 2.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 KFO96674.1 - 0.0028 17.6 0.9 0.0028 17.6 0.6 3.2 3 0 0 3 3 3 1 zinc-finger zf-RING_6 PF14835.1 KFO96674.1 - 0.013 15.2 3.3 0.073 12.8 2.3 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFO96674.1 - 0.019 14.7 6.7 0.039 13.6 1.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 KFO96674.1 - 0.089 12.3 3.3 0.19 11.3 2.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 KFO96674.1 - 0.1 12.1 8.1 0.1 12.0 0.2 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-HC5HC2H_2 PF13832.1 KFO96674.1 - 0.12 12.3 1.6 0.13 12.2 0.3 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFO96674.1 - 0.14 12.3 0.3 0.14 12.3 0.2 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain Opy2 PF09463.5 KFO96674.1 - 0.15 12.1 6.2 10 6.2 0.2 3.3 3 0 0 3 3 3 0 Opy2 protein zf-RING_4 PF14570.1 KFO96674.1 - 0.18 11.3 8.0 2 8.0 0.0 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.4 KFO96674.1 - 0.32 11.1 1.9 11 6.2 0.4 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_4 PF13894.1 KFO96674.1 - 0.46 10.9 7.7 1.4 9.4 0.0 3.8 3 2 0 3 3 3 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.7 KFO96674.1 - 0.69 9.2 5.7 7.4 5.9 0.1 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding TerY-C PF15616.1 KFO96674.1 - 0.95 9.3 3.5 0.88 9.4 0.9 1.9 2 0 0 2 2 2 0 TerY-C metal binding domain Prok-RING_1 PF14446.1 KFO96674.1 - 1.3 8.8 6.7 13 5.6 0.4 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-H2C2_2 PF13465.1 KFO96674.1 - 1.9 8.9 6.7 55 4.3 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.7 KFO96674.1 - 5 7.3 11.9 75 3.5 0.1 3.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.24 KFO96674.1 - 8.8 6.1 10.3 7 6.4 3.4 2.7 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.1 KFO96674.1 - 9.6 6.1 10.8 11 5.9 5.1 2.7 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING LIX1 PF14954.1 KFO96675.1 - 2e-139 462.7 0.8 2.2e-139 462.5 0.5 1.0 1 0 0 1 1 1 1 Limb expression 1 RRM_1 PF00076.17 KFO96676.1 - 8.6e-19 66.9 0.2 1.5e-18 66.1 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96676.1 - 1.7e-12 47.0 0.0 2.8e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96676.1 - 9.2e-11 41.4 0.0 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO96676.1 - 5.4e-06 26.1 0.1 2.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Arrestin_N PF00339.24 KFO96677.1 - 2.9e-21 75.8 0.0 5.2e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFO96677.1 - 2.9e-13 50.0 0.0 1.4e-12 47.8 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain RGM_N PF06535.7 KFO96678.1 - 1.4e-62 210.4 0.4 2e-62 209.9 0.3 1.2 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus RGM_C PF06534.8 KFO96678.1 - 4.5e-62 208.3 0.0 1e-61 207.2 0.0 1.6 1 1 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus MFS_1 PF07690.11 KFO96679.1 - 1.5e-28 99.5 45.3 1.6e-18 66.5 20.5 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFO96679.1 - 1.7e-20 73.0 31.7 1.4e-16 60.1 6.8 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter Pentapeptide_4 PF13599.1 KFO96679.1 - 8.5e-09 35.1 11.0 1.4e-08 34.3 6.9 1.8 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) DUF1228 PF06779.9 KFO96679.1 - 0.0017 18.3 0.9 0.0017 18.3 0.6 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) MFS_3 PF05977.8 KFO96679.1 - 0.0081 14.3 8.9 0.041 11.9 2.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Pentapeptide_3 PF13576.1 KFO96679.1 - 0.012 15.5 6.9 0.032 14.1 4.8 1.8 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) RRM_1 PF00076.17 KFO96680.1 - 1.9e-40 136.3 0.0 2.8e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96680.1 - 9.8e-26 89.5 0.0 1e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96680.1 - 2.2e-20 72.2 0.0 5e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFO96680.1 - 0.0027 17.4 0.1 0.52 10.0 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 KFO96680.1 - 0.0082 15.6 0.1 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain OTU PF02338.14 KFO96681.1 - 1.6e-27 96.4 0.0 3.7e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease UBA_4 PF14555.1 KFO96681.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Sec1 PF00995.18 KFO96682.1 - 4.5e-129 431.6 0.1 5.8e-129 431.2 0.1 1.1 1 0 0 1 1 1 1 Sec1 family PH PF00169.24 KFO96683.1 - 8.2e-11 42.0 0.6 2.2e-10 40.6 0.4 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFO96683.1 - 0.0011 19.1 0.7 0.021 14.9 0.5 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFO96683.1 - 0.0017 18.5 0.5 0.0017 18.5 0.4 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3439 PF11921.3 KFO96683.1 - 0.28 10.9 2.6 0.71 9.6 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LRR_8 PF13855.1 KFO96684.1 - 8.4e-21 73.4 28.3 1.4e-09 37.5 3.9 2.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KFO96684.1 - 2e-15 56.0 14.1 1.6e-11 43.5 2.1 2.9 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFO96684.1 - 2.1e-09 36.0 9.0 0.053 13.7 0.1 5.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 KFO96684.1 - 4.3e-09 36.1 0.6 5.5e-09 35.8 0.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KFO96684.1 - 3.6e-07 29.5 16.8 3e-05 23.6 0.2 4.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 KFO96684.1 - 5.1e-06 25.7 10.6 0.021 14.7 0.1 4.9 4 1 1 5 5 5 2 Leucine Rich Repeat TFIIA PF03153.8 KFO96684.1 - 0.42 10.4 14.2 0.43 10.4 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S21 PF01165.15 KFO96685.1 - 2.3e-11 42.9 2.9 3.1e-11 42.5 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 PRP3 PF08572.5 KFO96686.1 - 1.4e-70 237.1 5.6 1.4e-70 237.1 3.9 2.5 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KFO96686.1 - 2.2e-42 143.7 1.1 2.2e-42 143.7 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PWI PF01480.12 KFO96686.1 - 8.2e-17 61.0 0.0 2.9e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 PWI domain CTD_bind PF04818.8 KFO96687.1 - 1e-20 73.6 1.6 1.3e-20 73.3 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Het-C PF07217.6 KFO96687.1 - 0.071 11.2 0.0 0.12 10.4 0.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Acetyltransf_11 PF13720.1 KFO96687.1 - 0.15 12.3 0.1 34 4.7 0.0 2.7 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 tRNA-synt_2b PF00587.20 KFO96688.1 - 5.9e-35 120.3 0.0 1.1e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.9 KFO96688.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain XPC-binding PF09280.6 KFO96688.1 - 0.27 10.7 4.7 2.1 7.8 1.5 2.4 2 0 0 2 2 2 0 XPC-binding domain Ribosomal_S27e PF01667.12 KFO96689.1 - 7.3e-28 95.8 3.6 9.1e-28 95.5 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KFO96689.1 - 0.0052 16.6 1.2 0.0067 16.2 0.8 1.1 1 0 0 1 1 1 1 IBR domain DUF3795 PF12675.2 KFO96689.1 - 0.078 13.1 1.8 1.2 9.3 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) E7 PF00527.13 KFO96689.1 - 0.24 11.5 3.2 0.3 11.2 1.3 1.7 1 1 1 2 2 2 0 E7 protein, Early protein ubiquitin PF00240.18 KFO96690.1 - 6.1e-13 47.9 0.2 1e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KFO96690.1 - 6.6e-07 28.9 0.5 6.6e-07 28.9 0.3 2.3 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.3 KFO96690.1 - 0.00017 21.1 0.1 0.00032 20.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Arm_2 PF04826.8 KFO96690.1 - 0.024 13.7 0.2 0.024 13.7 0.1 2.7 3 0 0 3 3 3 0 Armadillo-like ComX PF05952.7 KFO96690.1 - 0.078 12.5 4.3 11 5.6 0.0 4.1 2 2 2 4 4 4 0 Bacillus competence pheromone ComX Rad60-SLD_2 PF13881.1 KFO96690.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Herpes_Helicase PF02689.9 KFO96690.1 - 0.2 9.3 0.2 0.28 8.8 0.1 1.1 1 0 0 1 1 1 0 Helicase Kinesin-relat_1 PF12711.2 KFO96690.1 - 0.46 10.9 14.2 8 6.9 1.2 4.3 2 1 2 4 4 4 0 Kinesin motor RAP1 PF07218.6 KFO96690.1 - 3.7 5.5 6.8 5.2 5.0 4.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Clathrin-link PF09268.5 KFO96690.1 - 6.3 5.9 9.1 35 3.5 0.2 3.9 3 0 0 3 3 3 0 Clathrin, heavy-chain linker Robl_LC7 PF03259.12 KFO96691.1 - 2.2e-13 49.5 0.0 2.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Ras PF00071.17 KFO96692.1 - 2.7e-57 192.6 0.0 3e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO96692.1 - 9.1e-16 58.4 0.0 1.2e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO96692.1 - 7.9e-12 44.7 0.0 9.2e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFO96692.1 - 2.1e-06 27.7 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFO96692.1 - 4e-05 22.8 0.0 0.00021 20.5 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFO96692.1 - 0.0001 22.4 0.0 0.00058 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KFO96692.1 - 0.00039 19.6 0.0 0.00044 19.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 KFO96692.1 - 0.00044 20.1 0.0 0.00079 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFO96692.1 - 0.0012 18.0 0.2 0.0041 16.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFO96692.1 - 0.0033 17.4 0.0 0.0096 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 KFO96692.1 - 0.0039 16.4 0.5 0.1 11.9 0.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3265 PF11665.3 KFO96692.1 - 0.0073 16.1 0.6 0.013 15.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3265) AAA_5 PF07728.9 KFO96692.1 - 0.018 14.7 0.1 0.041 13.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 KFO96692.1 - 0.019 13.9 0.0 0.028 13.4 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain cobW PF02492.14 KFO96692.1 - 0.024 14.1 0.1 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KFO96692.1 - 0.046 14.0 0.0 0.052 13.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 KFO96692.1 - 0.048 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 KFO96692.1 - 0.05 13.0 0.0 0.18 11.2 0.0 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KFO96692.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.1 KFO96692.1 - 0.099 12.5 0.2 0.71 9.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KFO96692.1 - 0.11 12.2 0.1 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 KFO96692.1 - 0.16 10.9 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 KFO96693.1 - 3.6e-62 208.5 0.1 4.1e-62 208.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO96693.1 - 3.8e-20 72.5 0.0 5.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO96693.1 - 1.2e-12 47.3 0.0 1.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFO96693.1 - 1.3e-07 31.6 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFO96693.1 - 4.2e-06 26.9 0.0 1.5e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KFO96693.1 - 0.00016 21.1 0.0 0.00043 19.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFO96693.1 - 0.00078 18.6 0.0 0.0014 17.7 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KFO96693.1 - 0.0013 17.9 0.0 0.0046 16.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFO96693.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KFO96693.1 - 0.0018 17.4 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 KFO96693.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KFO96693.1 - 0.014 15.6 0.1 0.027 14.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 KFO96693.1 - 0.018 14.3 0.1 0.052 12.8 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 KFO96693.1 - 0.018 15.0 0.3 0.052 13.5 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 KFO96693.1 - 0.045 13.3 0.1 0.21 11.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 KFO96693.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KFO96693.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KH_1 PF00013.24 KFO96694.1 - 2.2e-20 72.0 2.6 1.9e-14 53.0 0.3 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.1 KFO96694.1 - 4.6e-11 42.2 10.6 7.2e-11 41.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_3 PF13014.1 KFO96694.1 - 5.5e-11 41.8 0.3 2.7e-07 30.0 0.1 2.5 2 0 0 2 2 2 2 KH domain zf-C3HC4_2 PF13923.1 KFO96694.1 - 8.1e-08 32.1 12.0 1.4e-07 31.4 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO96694.1 - 4.5e-05 23.0 11.1 7.6e-05 22.2 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO96694.1 - 0.0009 19.0 12.7 0.0015 18.3 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFO96694.1 - 0.016 14.9 11.2 0.03 14.0 7.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain KH_2 PF07650.12 KFO96694.1 - 0.022 14.3 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 KH domain zf-C3HC4_4 PF15227.1 KFO96694.1 - 0.68 9.8 11.5 1.6 8.6 7.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFO96694.1 - 5.6 6.6 9.1 13 5.4 6.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Filament PF00038.16 KFO96695.1 - 4.2e-89 299.1 68.2 8e-89 298.1 47.3 1.5 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.14 KFO96695.1 - 2.6e-17 62.9 0.1 4.3e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Lamin Tail Domain Myosin_tail_1 PF01576.14 KFO96695.1 - 0.0009 17.1 70.5 0.0088 13.8 14.4 3.2 1 1 2 3 3 3 2 Myosin tail DUF869 PF05911.6 KFO96695.1 - 0.0017 16.6 7.7 0.0017 16.6 5.4 3.2 1 1 2 3 3 3 2 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 KFO96695.1 - 0.0045 16.8 63.1 0.012 15.4 15.6 3.7 1 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFO96695.1 - 0.55 9.3 15.9 1.4 7.9 1.3 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KFO96695.1 - 0.75 9.5 56.4 1.6 8.4 16.0 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFO96695.1 - 0.82 9.2 72.7 0.075 12.6 8.9 3.6 1 1 2 3 3 3 0 IncA protein Sema PF01403.14 KFO96696.1 - 6.2e-79 265.5 0.0 6.9e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Sema domain Mito_carr PF00153.22 KFO96697.1 - 6.1e-47 157.2 7.0 3.3e-16 58.7 0.4 3.3 2 2 1 3 3 3 3 Mitochondrial carrier protein Nnf1 PF03980.9 KFO96698.1 - 6.9e-25 87.1 0.4 8.6e-25 86.8 0.3 1.1 1 0 0 1 1 1 1 Nnf1 LRR_6 PF13516.1 KFO96699.1 - 2.4e-05 23.9 4.5 0.053 13.6 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 KFO96699.1 - 0.0078 16.2 4.7 18 6.1 0.1 4.5 4 0 0 4 4 4 1 Leucine rich repeat F-box-like PF12937.2 KFO96699.1 - 0.0079 15.8 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KFO96699.1 - 0.015 14.8 5.2 0.036 13.7 1.0 3.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96699.1 - 0.018 15.0 4.0 9.9 6.6 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 KFO96699.1 - 0.12 12.0 2.5 0.37 10.5 1.1 2.3 1 1 0 1 1 1 0 Leucine rich repeat Adeno_E4_34 PF04528.8 KFO96699.1 - 0.79 9.2 4.9 4.1 6.9 3.4 2.1 1 1 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region UCH PF00443.24 KFO96700.1 - 1e-68 231.3 0.8 2.1e-68 230.3 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO96700.1 - 9.2e-28 97.5 0.5 6.1e-27 94.8 0.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFO96700.1 - 5.5e-19 68.0 11.4 5.5e-19 68.0 7.9 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Carb_anhydrase PF00194.16 KFO96701.1 - 6.1e-71 238.3 0.0 6.8e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ras PF00071.17 KFO96702.1 - 3.2e-51 172.9 0.4 4e-51 172.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO96702.1 - 4.5e-13 49.7 0.0 8.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO96702.1 - 9.4e-12 44.5 0.4 1.1e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO96702.1 - 9.7e-05 21.8 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFO96702.1 - 0.0035 16.5 0.1 0.0042 16.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3963 PF13124.1 KFO96702.1 - 0.015 15.0 0.9 0.027 14.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Ribosomal_S27e PF01667.12 KFO96703.1 - 3.4e-30 103.3 5.2 4.1e-30 103.0 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KFO96703.1 - 0.014 15.2 2.4 0.018 14.9 1.6 1.2 1 0 0 1 1 1 0 IBR domain DUF3795 PF12675.2 KFO96703.1 - 0.14 12.3 2.6 1.4 9.1 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) E7 PF00527.13 KFO96703.1 - 0.51 10.5 3.0 0.65 10.1 1.3 1.7 1 1 1 2 2 2 0 E7 protein, Early protein Beta-lactamase PF00144.19 KFO96704.1 - 6.3e-51 173.3 0.0 1.6e-27 96.3 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase SH3BP5 PF05276.9 KFO96704.1 - 0.0022 17.3 0.2 0.0037 16.6 0.2 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Peptidase_S11 PF00768.15 KFO96704.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Tropomyosin PF00261.15 KFO96705.1 - 5.4e-106 353.0 87.6 1.1e-100 335.6 43.4 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFO96705.1 - 5e-40 136.6 78.1 3.8e-36 124.0 30.0 3.0 1 1 1 3 3 3 3 Tropomyosin like Laminin_II PF06009.7 KFO96705.1 - 2.3e-06 27.3 38.7 1.8e-05 24.4 4.8 4.0 1 1 2 4 4 4 3 Laminin Domain II TMF_DNA_bd PF12329.3 KFO96705.1 - 2.3e-05 24.0 9.5 2.3e-05 24.0 6.6 6.2 1 1 3 5 5 5 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KFO96705.1 - 0.00025 20.7 62.8 0.00092 18.8 17.6 2.9 1 1 2 3 3 2 2 IncA protein CENP-F_leu_zip PF10473.4 KFO96705.1 - 0.0015 18.4 66.8 0.0037 17.1 21.6 2.3 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 KFO96705.1 - 0.0042 16.4 49.5 0.46 9.7 13.4 3.1 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain ATG16 PF08614.6 KFO96705.1 - 0.0076 16.0 9.1 0.0076 16.0 6.3 3.5 1 1 2 3 3 2 1 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 KFO96705.1 - 0.019 12.7 69.8 0.016 12.9 36.3 2.6 1 1 1 2 2 2 0 Myosin tail AAA_13 PF13166.1 KFO96705.1 - 0.02 13.3 51.7 0.0081 14.6 22.3 2.1 1 1 1 2 2 2 0 AAA domain Sugarporin_N PF11471.3 KFO96705.1 - 0.025 14.2 10.2 0.025 14.2 7.0 6.4 5 3 2 7 7 7 0 Maltoporin periplasmic N-terminal extension Flagellin_N PF00669.15 KFO96705.1 - 0.042 13.6 18.2 0.36 10.6 3.4 3.5 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region DUF869 PF05911.6 KFO96705.1 - 0.075 11.2 55.1 0.27 9.4 18.6 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Laminin_I PF06008.9 KFO96705.1 - 0.11 11.7 54.5 0.19 11.0 8.8 3.1 1 1 2 3 3 3 0 Laminin Domain I SlyX PF04102.7 KFO96705.1 - 0.18 12.1 38.3 0.65 10.4 0.6 5.8 1 1 5 6 6 6 0 SlyX WEMBL PF05701.6 KFO96705.1 - 0.2 10.0 70.0 0.097 11.1 13.4 3.7 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KFO96705.1 - 0.34 10.0 10.7 0.5 9.4 1.0 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DASH_Hsk3 PF08227.6 KFO96705.1 - 0.41 10.8 2.2 8.9 6.6 0.1 2.7 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Nup54 PF13874.1 KFO96705.1 - 0.43 10.2 36.2 0.58 9.8 1.2 3.8 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 AAA_27 PF13514.1 KFO96705.1 - 0.76 7.3 55.4 0.97 7.0 38.4 1.1 1 0 0 1 1 1 0 AAA domain DUF745 PF05335.8 KFO96705.1 - 0.77 9.2 46.5 0.82 9.1 6.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF745) ADIP PF11559.3 KFO96705.1 - 0.94 9.3 54.3 1.7 8.5 10.4 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding RmuC PF02646.11 KFO96705.1 - 0.96 8.2 31.0 0.41 9.4 3.9 3.9 1 1 3 4 4 4 0 RmuC family gpW PF02831.10 KFO96705.1 - 1.2 8.7 10.0 4.7 6.8 0.2 3.6 4 0 0 4 4 3 0 gpW DUF4200 PF13863.1 KFO96705.1 - 1.8 8.4 71.3 2.7 7.9 18.6 4.4 1 1 3 4 4 3 0 Domain of unknown function (DUF4200) Flagellin_C PF00700.16 KFO96705.1 - 2.3 8.4 17.2 1.4 9.0 1.2 4.4 1 1 3 5 5 5 0 Bacterial flagellin C-terminal helical region EzrA PF06160.7 KFO96705.1 - 2.6 6.1 50.3 2.2 6.3 11.5 2.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DASH_Dam1 PF08653.5 KFO96705.1 - 2.7 7.8 9.6 5.1 6.9 0.1 4.2 5 1 0 5 5 4 0 DASH complex subunit Dam1 NPV_P10 PF05531.7 KFO96705.1 - 3.4 7.9 20.8 10 6.4 0.5 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 KFO96705.1 - 3.5 6.7 63.4 1.6 7.9 12.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 KFO96705.1 - 3.9 4.6 58.4 2.6 5.2 18.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ERM PF00769.14 KFO96705.1 - 4.8 6.6 72.2 0.03 13.8 16.3 2.9 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DUF4407 PF14362.1 KFO96705.1 - 6.4 5.6 43.9 0.92 8.4 18.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) APG6 PF04111.7 KFO96705.1 - 8.6 5.2 65.7 0.33 9.9 15.5 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 VBS PF08913.5 KFO96706.1 - 1.8e-69 231.7 105.0 2.6e-68 228.0 0.4 12.7 11 3 1 12 12 12 5 Vinculin Binding Site Talin_middle PF09141.5 KFO96706.1 - 2.6e-69 232.0 4.9 2.6e-69 232.0 3.4 15.6 11 4 5 17 17 17 4 Talin, middle domain I_LWEQ PF01608.12 KFO96706.1 - 2.5e-58 196.3 185.0 4.4e-47 159.8 9.4 17.3 7 4 9 17 17 17 8 I/LWEQ domain FERM_N PF09379.5 KFO96706.1 - 6.7e-26 90.1 1.9 4.1e-24 84.4 0.4 3.2 3 0 0 3 3 3 1 FERM N-terminal domain FERM_M PF00373.13 KFO96706.1 - 1.1e-24 87.0 3.3 5.1e-24 84.8 0.0 3.4 2 0 0 2 2 2 1 FERM central domain IRS PF02174.12 KFO96706.1 - 4.9e-05 22.8 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) NS3_envE PF02723.9 KFO96706.1 - 0.47 10.3 0.2 1 9.3 0.1 1.5 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E DUF2605 PF10792.4 KFO96706.1 - 2.1 8.0 11.5 0.31 10.7 1.1 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) C2 PF00168.25 KFO96708.1 - 2.9e-10 39.8 0.0 5.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF1162 PF06650.7 KFO96709.1 - 4.7e-67 226.1 0.2 1.2e-66 224.7 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KFO96709.1 - 2.4e-22 78.6 0.4 2.2e-21 75.6 0.1 3.0 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KFO96709.1 - 2.3e-06 27.6 1.4 2.8e-05 24.1 0.0 3.5 4 0 0 4 4 4 1 ATG C terminal domain WWE PF02825.15 KFO96709.1 - 0.0078 15.6 0.1 0.025 13.9 0.1 1.9 1 0 0 1 1 1 1 WWE domain Hormone_recep PF00104.25 KFO96710.1 - 9e-35 119.6 2.4 9e-35 119.6 1.6 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO96710.1 - 3.8e-33 113.5 12.8 3.8e-33 113.5 8.9 2.3 3 0 0 3 3 3 1 Zinc finger, C4 type (two domains) NARG2_C PF10505.4 KFO96711.1 - 4e-65 219.0 0.7 7.3e-65 218.2 0.5 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Annexin PF00191.15 KFO96712.1 - 4.6e-92 301.9 10.4 9.1e-27 92.7 0.3 4.1 4 0 0 4 4 4 4 Annexin DUF1706 PF08020.6 KFO96712.1 - 0.076 12.5 0.1 0.93 8.9 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1706) Fork_head PF00250.13 KFO96713.1 - 4.1e-46 154.9 0.1 4.5e-46 154.8 0.0 1.0 1 0 0 1 1 1 1 Fork head domain BNIP2 PF12496.3 KFO96714.1 - 3.2e-40 137.2 2.1 5e-40 136.6 1.4 1.3 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 KFO96714.1 - 3.5e-28 98.3 0.1 5.5e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFO96714.1 - 6.4e-09 35.4 0.1 9.6e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain TFIIA_gamma_C PF02751.9 KFO96715.1 - 5.7e-24 83.6 2.6 8.1e-24 83.1 1.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KFO96715.1 - 1e-23 82.6 0.6 1.5e-23 82.1 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain OTU PF02338.14 KFO96717.1 - 5.4e-29 101.2 0.0 1.5e-28 99.7 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease DDHD PF02862.12 KFO96717.1 - 1.2 8.9 6.1 2.5 7.8 4.3 1.5 1 0 0 1 1 1 0 DDHD domain zf-H2C2_2 PF13465.1 KFO96718.1 - 1.5e-14 53.4 26.7 1.2e-07 31.6 1.8 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO96718.1 - 1.3e-13 50.3 23.2 0.0001 22.4 0.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96718.1 - 6.4e-11 41.7 20.2 0.0002 21.4 0.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFO96718.1 - 0.0026 17.8 10.2 0.49 10.6 0.3 4.2 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-BED PF02892.10 KFO96718.1 - 0.049 13.3 13.8 0.19 11.5 1.6 2.9 2 1 1 3 3 3 0 BED zinc finger zf-Di19 PF05605.7 KFO96718.1 - 0.92 9.6 5.3 0.28 11.3 1.3 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BIR PF00653.16 KFO96718.1 - 7.2 7.1 8.8 1.5 9.2 1.6 2.2 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Ion_trans PF00520.26 KFO96719.1 - 7.6e-10 38.3 14.2 7.6e-10 38.3 9.9 2.4 2 1 0 2 2 2 1 Ion transport protein TLV_coat PF00429.14 KFO96720.1 - 0.0044 15.5 0.1 0.0047 15.4 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) DASH_Duo1 PF08651.5 KFO96720.1 - 0.017 14.6 0.1 0.022 14.3 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 CTC1_2 PF15491.1 KFO96720.1 - 0.067 12.1 0.0 0.071 12.1 0.0 1.0 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 7tm_4 PF13853.1 KFO96721.1 - 2.2e-58 196.1 13.6 2.2e-58 196.1 9.4 1.9 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO96721.1 - 4.8e-28 98.0 12.5 6.4e-28 97.5 8.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) VWD PF00094.20 KFO96722.1 - 1.4e-31 109.8 2.5 1.4e-31 109.8 1.7 2.0 2 0 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 KFO96722.1 - 1.3e-22 79.8 15.8 1.3e-22 79.8 11.0 2.3 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 KFO96722.1 - 2.5e-05 24.2 4.7 2.5e-05 24.2 3.3 4.9 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.13 KFO96722.1 - 5.9e-05 23.0 8.9 5.9e-05 23.0 6.2 4.5 3 2 1 4 4 4 1 von Willebrand factor type C domain Cys_knot PF00007.17 KFO96723.1 - 1.7e-10 40.8 18.3 1.7e-10 40.8 12.7 3.6 1 1 3 4 4 4 1 Cystine-knot domain VWC PF00093.13 KFO96723.1 - 4.4e-08 33.1 32.3 1.5e-06 28.1 8.5 3.7 2 1 1 3 3 3 2 von Willebrand factor type C domain CUE PF02845.11 KFO96724.1 - 3.4e-16 58.3 0.2 8.1e-16 57.1 0.1 1.7 1 0 0 1 1 1 1 CUE domain C2 PF00168.25 KFO96724.1 - 8.3e-10 38.3 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain UBA PF00627.26 KFO96724.1 - 0.0014 18.4 0.1 0.0028 17.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.14 KFO96724.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Pkinase PF00069.20 KFO96725.1 - 7.8e-63 212.0 0.0 1.2e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96725.1 - 7.2e-33 113.7 0.0 9.5e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFO96725.1 - 7.3e-05 22.6 0.1 0.0012 18.6 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFO96725.1 - 0.0028 17.2 0.1 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KFO96725.1 - 0.0044 16.0 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO96725.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.12 KFO96726.1 - 1.7e-59 200.3 4.8 2e-59 200.1 3.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family DSPc PF00782.15 KFO96727.1 - 2.6e-44 150.0 0.0 4.1e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFO96727.1 - 2.2e-12 47.3 0.0 5.3e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 KFO96727.1 - 6.6e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFO96727.1 - 0.0036 17.3 0.0 0.0093 16.0 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Dispanin PF04505.7 KFO96728.1 - 2.3e-21 75.1 0.1 3.4e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Interferon-induced transmembrane protein ScdA_N PF04405.9 KFO96728.1 - 0.068 12.5 0.5 0.26 10.7 0.2 2.0 1 1 1 2 2 2 0 Domain of Unknown function (DUF542) Asp PF00026.18 KFO96729.1 - 1.1e-127 425.6 0.0 1.3e-127 425.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFO96729.1 - 5.3e-10 39.4 0.0 6.4e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 KFO96729.1 - 9.9e-08 31.5 0.0 9.9e-07 28.3 0.0 2.2 2 0 0 2 2 2 1 A1 Propeptide TAXi_C PF14541.1 KFO96729.1 - 4.4e-06 26.3 0.0 1.8e-05 24.3 0.0 2.0 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFO96729.1 - 6.7e-05 23.3 0.3 0.23 11.9 0.1 3.2 2 1 0 2 2 2 2 Aspartyl protease 5-nucleotidase PF06189.7 KFO96730.1 - 2.6e-86 288.7 0.0 1.8e-84 282.6 0.0 1.8 1 1 1 2 2 2 2 5'-nucleotidase Troponin PF00992.15 KFO96731.1 - 1.7e-53 180.1 10.0 1.7e-53 180.1 6.9 1.4 2 0 0 2 2 2 1 Troponin DUF919 PF06034.6 KFO96731.1 - 0.011 15.3 2.3 0.011 15.3 1.6 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Tropomyosin_1 PF12718.2 KFO96731.1 - 0.018 14.8 0.8 0.018 14.8 0.6 3.0 3 0 0 3 3 3 0 Tropomyosin like Laminin_II PF06009.7 KFO96731.1 - 0.034 13.8 3.2 0.059 13.1 1.4 1.9 1 1 1 2 2 2 0 Laminin Domain II SASP_gamma PF04259.9 KFO96731.1 - 0.082 13.0 0.5 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type DUF2408 PF10303.4 KFO96731.1 - 0.087 12.9 6.0 0.22 11.6 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Matrilin_ccoil PF10393.4 KFO96731.1 - 0.16 11.3 2.3 1.8 7.9 0.2 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin His_Phos_2 PF00328.17 KFO96731.1 - 0.19 11.0 0.1 0.19 11.0 0.1 2.0 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) V_ATPase_I PF01496.14 KFO96731.1 - 0.25 9.1 3.2 0.13 10.0 0.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 KFO96731.1 - 0.29 10.9 4.6 0.11 12.3 0.8 2.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 KFO96731.1 - 0.43 10.4 15.8 1.2 8.9 8.8 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SbcD_C PF12320.3 KFO96731.1 - 0.49 10.4 4.5 0.57 10.2 1.1 2.4 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain HAUS-augmin3 PF14932.1 KFO96731.1 - 1.4 8.0 9.6 0.43 9.7 2.7 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 KFO96731.1 - 1.5 8.3 10.8 6.6 6.2 7.5 2.0 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 KFO96731.1 - 1.5 7.7 12.7 0.34 9.8 3.4 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Microtub_bind PF13931.1 KFO96731.1 - 2.7 8.1 7.1 1.9 8.5 1.3 2.1 1 1 0 2 2 2 0 Kinesin-associated microtubule-binding Erp_C PF06780.6 KFO96731.1 - 4 7.2 14.5 2.4 7.9 2.2 2.3 1 1 1 2 2 2 0 Erp protein C-terminus TMF_DNA_bd PF12329.3 KFO96731.1 - 6.8 6.5 17.9 0.1 12.4 1.7 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4643 PF15485.1 KFO96732.1 - 4.2e-51 174.1 16.3 5.5e-51 173.7 11.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4643) Troponin PF00992.15 KFO96734.1 - 2.8e-38 130.9 41.3 3.7e-37 127.3 24.5 2.0 2 0 0 2 2 2 2 Troponin Peptidase_S64 PF08192.6 KFO96734.1 - 0.18 10.1 6.5 0.21 9.8 4.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.8 KFO96734.1 - 0.33 10.1 21.5 0.43 9.7 14.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tfb4 PF03850.9 KFO96734.1 - 1.6 7.8 4.6 2.2 7.4 3.2 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Ribosomal_L23 PF00276.15 KFO96735.1 - 3.7e-10 39.6 0.7 5.3e-10 39.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 Insulin PF00049.13 KFO96736.1 - 2.8e-14 53.6 5.5 1.2e-06 29.1 1.6 2.4 1 1 1 2 2 2 2 Insulin/IGF/Relaxin family IGF2_C PF08365.6 KFO96736.1 - 3.7e-07 29.7 0.9 7.4e-07 28.8 0.6 1.5 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide Ins_beta PF03488.9 KFO96736.1 - 0.45 10.3 5.0 5 7.0 0.1 2.4 2 1 0 2 2 2 0 Nematode insulin-related peptide beta type Insulin PF00049.13 KFO96737.1 - 3.8e-24 85.2 1.0 4.8e-24 84.9 0.7 1.1 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family TRM13 PF05206.9 KFO96737.1 - 0.0063 15.7 0.3 0.018 14.2 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase TRM13 Ins_beta PF03488.9 KFO96737.1 - 0.016 14.9 5.2 0.37 10.6 0.1 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Biopterin_H PF00351.16 KFO96738.1 - 3.2e-195 647.3 0.6 4e-195 647.0 0.4 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase TOH_N PF12549.3 KFO96738.1 - 4.8e-20 70.3 0.6 3.8e-12 45.3 0.2 2.8 2 0 0 2 2 2 2 Tyrosine hydroxylase N terminal DUF4559 PF15112.1 KFO96738.1 - 0.12 11.5 0.0 0.39 9.8 0.1 1.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4559) Tetraspannin PF00335.15 KFO96739.1 - 1.3e-17 63.8 3.9 1.7e-17 63.4 2.7 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF4131 PF13567.1 KFO96739.1 - 0.011 15.2 0.8 0.02 14.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Claudin_2 PF13903.1 KFO96739.1 - 0.02 14.6 4.5 0.24 11.0 1.5 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF998 PF06197.8 KFO96739.1 - 0.038 13.2 3.7 0.03 13.6 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF998) GWT1 PF06423.7 KFO96739.1 - 0.07 13.2 1.7 0.092 12.8 0.4 1.8 2 0 0 2 2 2 0 GWT1 DUF2975 PF11188.3 KFO96739.1 - 5.3 6.7 6.9 1.3 8.7 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Tetraspannin PF00335.15 KFO96740.1 - 1.8e-39 135.2 12.1 2.1e-39 135.0 8.4 1.0 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 KFO96740.1 - 0.068 12.8 4.7 0.19 11.3 1.1 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TSSC4 PF15264.1 KFO96741.1 - 4.8e-29 101.1 0.0 1.6e-28 99.4 0.0 1.9 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 Ion_trans PF00520.26 KFO96742.1 - 3.5e-05 23.1 24.7 3.5e-05 23.1 17.1 3.0 3 1 0 3 3 3 1 Ion transport protein Mso1_Sec1_bdg PF14475.1 KFO96742.1 - 0.0047 16.3 0.1 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 Sec1-binding region of Mso1 Ion_trans PF00520.26 KFO96743.1 - 2.3e-24 85.7 8.1 2.3e-24 85.7 5.6 1.8 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFO96743.1 - 1.5e-11 43.8 7.0 1.5e-11 43.8 4.8 2.6 2 0 0 2 2 2 1 Ion channel Dispanin PF04505.7 KFO96743.1 - 0.05 13.1 0.8 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Interferon-induced transmembrane protein 2TM PF13239.1 KFO96743.1 - 3.9 7.5 8.4 0.41 10.7 1.8 2.4 3 0 0 3 3 3 0 2TM domain Phe_tRNA-synt_N PF02912.13 KFO96744.1 - 0.06 13.0 0.3 4.9 6.9 0.0 3.0 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain MFS_1 PF07690.11 KFO96745.1 - 5.1e-37 127.4 47.3 8.9e-34 116.7 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KFO96745.1 - 1.3e-09 36.7 18.1 1.1e-06 27.0 5.2 3.0 2 1 1 3 3 3 3 Transmembrane secretion effector MFS_1_like PF12832.2 KFO96745.1 - 0.069 12.9 5.9 0.1 12.4 0.0 3.5 5 0 0 5 5 5 0 MFS_1 like family Bacteriocin_IIc PF10439.4 KFO96745.1 - 9 6.5 10.1 25 5.0 2.9 3.0 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide PH PF00169.24 KFO96746.1 - 4.7e-06 26.7 0.1 6.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 PH domain NAP PF00956.13 KFO96747.1 - 6e-88 294.0 5.3 9.2e-88 293.4 3.7 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) tRNA-synt_1e PF01406.14 KFO96748.1 - 1.1e-99 333.3 0.0 1.1e-99 333.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain GST_C_3 PF14497.1 KFO96748.1 - 0.034 14.6 0.7 0.19 12.1 0.0 2.7 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain TNFR_c6 PF00020.13 KFO96749.1 - 4.3e-08 33.0 9.0 4.3e-08 33.0 6.2 3.4 2 1 0 3 3 3 2 TNFR/NGFR cysteine-rich region Y_phosphatase PF00102.22 KFO96750.1 - 3.7e-87 291.5 1.7 7.4e-87 290.5 1.2 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.16 KFO96750.1 - 5.6e-51 170.6 28.2 3e-10 40.0 0.6 7.4 7 0 0 7 7 7 6 Fibronectin type III domain Y_Y_Y PF07495.8 KFO96750.1 - 2.3e-14 52.8 5.1 0.033 13.9 0.1 5.5 6 0 0 6 6 6 4 Y_Y_Y domain DSPc PF00782.15 KFO96750.1 - 0.00028 20.4 0.0 0.00076 19.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFO96750.1 - 0.00035 20.6 0.6 0.0025 17.8 0.0 2.8 3 1 1 4 4 4 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFO96750.1 - 0.0015 18.7 0.1 0.0072 16.5 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KFO96750.1 - 0.0022 17.3 0.1 0.0048 16.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Syndecan PF01034.15 KFO96750.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4010 PF13194.1 KFO96750.1 - 0.074 12.3 0.1 1.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) MecA_N PF05223.6 KFO96750.1 - 0.26 11.3 11.7 11 6.1 0.1 4.6 5 0 0 5 5 5 0 NTF2-like N-terminal transpeptidase domain SKG6 PF08693.5 KFO96750.1 - 0.59 9.4 2.7 1.7 8.0 1.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CpcD PF01383.16 KFO96750.1 - 1.3 9.2 6.8 2.1e+02 2.1 0.0 5.0 4 0 0 4 4 4 0 CpcD/allophycocyanin linker domain Y_phosphatase PF00102.22 KFO96751.1 - 2.9e-74 249.3 0.9 4.9e-74 248.5 0.6 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFO96751.1 - 6.1e-07 29.0 0.0 1.8e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFO96751.1 - 0.00098 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF307 PF03733.8 KFO96751.1 - 0.01 16.2 1.1 0.031 14.6 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF307) Oxidored_q1_C PF01010.14 KFO96751.1 - 0.019 14.4 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus PTPlike_phytase PF14566.1 KFO96751.1 - 0.028 14.4 0.0 0.081 12.9 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Myotub-related PF06602.9 KFO96751.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain YhhN PF07947.9 KFO96752.1 - 3.6e-46 156.8 25.1 3.6e-46 156.8 17.4 1.3 2 0 0 2 2 2 1 YhhN-like protein YtpI PF14007.1 KFO96752.1 - 4.4 7.3 10.1 0.44 10.4 0.4 3.0 2 1 1 4 4 4 0 YtpI-like protein SPT2 PF08243.6 KFO96753.1 - 2.2e-28 98.8 16.0 2.2e-28 98.8 11.1 3.9 4 0 0 4 4 4 1 SPT2 chromatin protein UEV PF05743.8 KFO96754.1 - 1.1e-41 141.3 0.2 1.7e-41 140.6 0.2 1.3 1 0 0 1 1 1 1 UEV domain Ldh_1_N PF00056.18 KFO96754.1 - 8.7e-23 80.7 0.6 1.5e-22 79.9 0.4 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFO96754.1 - 1.7e-15 57.2 0.0 4.2e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.12 KFO96754.1 - 0.032 14.6 0.7 0.094 13.1 0.3 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFO96754.1 - 0.2 11.2 1.1 0.27 10.8 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UEV PF05743.8 KFO96755.1 - 8.9e-46 154.5 2.4 1.6e-45 153.6 0.1 2.1 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 KFO96755.1 - 1.3e-28 98.3 0.2 2.3e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 KFO96755.1 - 0.0015 17.9 0.5 0.0015 17.9 0.4 1.8 2 0 0 2 2 1 1 Ubiquitin-conjugating enzyme APG6 PF04111.7 KFO96755.1 - 0.0028 16.7 7.4 0.0039 16.2 5.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3450 PF11932.3 KFO96755.1 - 0.0054 16.0 6.7 0.0054 16.0 4.7 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Macoilin PF09726.4 KFO96755.1 - 0.019 13.2 4.8 0.025 12.9 3.3 1.1 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 KFO96755.1 - 0.025 12.4 2.4 0.031 12.1 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFO96755.1 - 0.028 13.9 6.6 0.039 13.5 4.5 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 KFO96755.1 - 0.032 14.6 3.9 0.032 14.6 2.7 2.9 2 1 1 3 3 3 0 SlyX DUF1640 PF07798.6 KFO96755.1 - 0.048 13.6 8.5 0.048 13.7 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) TBPIP PF07106.8 KFO96755.1 - 0.05 13.1 7.8 0.078 12.5 5.4 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 KFO96755.1 - 0.059 11.7 4.9 0.081 11.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LXG PF04740.7 KFO96755.1 - 0.081 12.6 4.4 0.14 11.9 3.1 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Spc24 PF08286.6 KFO96755.1 - 0.11 12.1 13.0 0.28 10.8 4.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF848 PF05852.6 KFO96755.1 - 0.12 12.1 4.5 0.22 11.3 3.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2317 PF10079.4 KFO96755.1 - 0.17 10.4 4.9 0.25 9.8 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Nup88 PF10168.4 KFO96755.1 - 0.18 9.6 3.8 0.26 9.0 2.6 1.1 1 0 0 1 1 1 0 Nuclear pore component Reo_sigmaC PF04582.7 KFO96755.1 - 0.18 10.9 0.3 0.26 10.4 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1002 PF06207.6 KFO96755.1 - 0.2 10.9 5.7 0.3 10.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Fzo_mitofusin PF04799.8 KFO96755.1 - 0.2 11.0 4.3 0.36 10.1 3.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region Nsp1_C PF05064.8 KFO96755.1 - 0.25 11.0 7.8 0.21 11.2 3.8 2.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region FlxA PF14282.1 KFO96755.1 - 0.37 10.7 4.6 0.63 10.0 3.2 1.3 1 0 0 1 1 1 0 FlxA-like protein Bap31 PF05529.7 KFO96755.1 - 0.4 10.1 5.6 0.66 9.4 3.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF641 PF04859.7 KFO96755.1 - 0.75 9.5 6.2 1.4 8.6 4.3 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HSP70 PF00012.15 KFO96755.1 - 0.81 7.5 5.8 0.99 7.2 4.0 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF724 PF05266.9 KFO96755.1 - 0.86 9.1 8.6 1.4 8.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.17 KFO96755.1 - 0.88 9.6 10.8 0.76 9.8 5.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3552 PF12072.3 KFO96755.1 - 0.88 8.7 12.1 1.4 8.1 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) NPV_P10 PF05531.7 KFO96755.1 - 1.4 9.2 5.7 3.4 7.9 2.6 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 KFO96755.1 - 3.4 7.3 10.5 2.7 7.6 1.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF4164 PF13747.1 KFO96755.1 - 4.1 7.5 12.1 2.6 8.2 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Prefoldin_2 PF01920.15 KFO96755.1 - 4.7 7.0 15.1 4.2 7.1 2.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 KFO96755.1 - 5.7 6.4 13.0 0.37 10.2 1.3 2.8 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Ldh_1_N PF00056.18 KFO96756.1 - 1.2e-46 158.0 0.2 1.7e-46 157.5 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFO96756.1 - 1.6e-31 109.3 0.0 5.8e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 KFO96756.1 - 0.0045 16.3 0.5 0.026 13.8 0.0 2.2 3 0 0 3 3 3 1 Family 4 glycosyl hydrolase Pertactin PF03212.9 KFO96756.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Pertactin BSD PF03909.12 KFO96757.1 - 4.5e-29 99.9 1.0 2.1e-15 56.1 0.0 2.9 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KFO96757.1 - 8.6e-22 76.5 0.0 1.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF2652 PF10851.3 KFO96757.1 - 0.035 14.0 0.2 8 6.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2652) DUF3639 PF12341.3 KFO96758.1 - 0.024 14.6 0.9 4.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) SAA PF00277.13 KFO96759.1 - 1.7e-44 150.3 10.2 1.8e-44 150.2 7.0 1.0 1 0 0 1 1 1 1 Serum amyloid A protein SCRG1 PF15224.1 KFO96760.1 - 0.034 13.9 0.2 0.047 13.5 0.1 1.3 1 0 0 1 1 1 0 Scrapie-responsive protein 1 Golgin_A5 PF09787.4 KFO96760.1 - 0.049 12.1 1.0 0.053 12.0 0.7 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 IKKbetaNEMObind PF12179.3 KFO96760.1 - 0.3 10.9 3.2 0.23 11.3 0.5 2.0 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Biopterin_H PF00351.16 KFO96761.1 - 1.2e-176 586.3 0.1 1.5e-176 585.9 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 KFO96761.1 - 1.8e-07 30.4 0.0 3.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain RCC1 PF00415.13 KFO96762.1 - 1.9e-60 200.8 28.0 7.1e-12 45.3 0.1 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFO96762.1 - 7.2e-31 105.1 56.5 4.1e-10 38.9 0.5 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Ion_trans PF00520.26 KFO96763.1 - 1.6e-32 112.4 8.4 1.6e-32 112.4 5.9 1.5 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFO96763.1 - 1.4e-21 76.5 0.0 1.7e-16 60.2 0.0 2.7 1 1 1 2 2 2 2 BTB/POZ domain Ion_trans_2 PF07885.11 KFO96763.1 - 8.4e-11 41.4 2.9 8.4e-11 41.4 2.0 2.5 2 0 0 2 2 2 1 Ion channel DUF202 PF02656.10 KFO96763.1 - 0.66 10.2 4.3 1.2e+02 2.9 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PKD_channel PF08016.7 KFO96763.1 - 5 5.4 9.0 1 7.6 2.5 2.0 1 1 1 2 2 2 0 Polycystin cation channel Basic PF01586.11 KFO96764.1 - 1.5e-30 105.7 2.4 1.5e-30 105.7 1.7 2.1 2 0 0 2 2 2 1 Myogenic Basic domain Myf5 PF12232.3 KFO96764.1 - 7.6e-28 96.9 10.3 7.6e-28 96.9 7.1 2.0 2 0 0 2 2 2 1 Myogenic determination factor 5 HLH PF00010.21 KFO96764.1 - 1.5e-15 56.6 3.5 3e-15 55.6 2.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FliO PF04347.8 KFO96765.1 - 0.12 12.4 1.5 0.16 12.0 1.1 1.2 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO Ferritin PF00210.19 KFO96766.1 - 8e-19 67.7 0.6 1e-18 67.4 0.1 1.4 2 0 0 2 2 2 1 Ferritin-like domain DUF837 PF05769.6 KFO96766.1 - 0.09 12.3 0.7 0.25 10.8 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF837) ABC_membrane PF00664.18 KFO96767.1 - 5.8e-71 239.1 33.6 4.8e-38 131.1 2.7 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFO96767.1 - 5e-52 175.8 0.2 1.9e-24 86.5 0.0 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KFO96767.1 - 3e-11 42.9 3.6 5.1e-05 22.6 0.0 3.3 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFO96767.1 - 1.1e-08 35.3 0.6 0.61 9.9 0.0 4.4 2 2 0 3 3 3 3 AAA domain AAA_25 PF13481.1 KFO96767.1 - 1.4e-07 31.1 0.0 0.0006 19.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KFO96767.1 - 0.0001 21.0 1.0 0.034 12.7 0.0 3.1 3 1 0 3 3 3 1 Predicted ATPase of the ABC class Miro PF08477.8 KFO96767.1 - 0.00011 22.7 0.0 0.34 11.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFO96767.1 - 0.00017 21.0 0.3 0.14 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFO96767.1 - 0.00024 20.3 0.0 0.0082 15.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFO96767.1 - 0.0015 18.4 0.0 0.21 11.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 KFO96767.1 - 0.0022 18.3 2.2 0.32 11.3 0.3 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFO96767.1 - 0.0056 16.6 0.2 0.05 13.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 KFO96767.1 - 0.0063 15.4 0.0 0.41 9.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 KFO96767.1 - 0.01 15.3 0.1 0.46 9.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 KFO96767.1 - 0.01 14.9 0.1 0.3 10.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 KFO96767.1 - 0.011 15.5 3.4 0.032 14.0 0.0 2.8 3 0 0 3 3 3 0 Dynamin family AAA_10 PF12846.2 KFO96767.1 - 0.023 14.1 0.5 2.8 7.3 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KFO96767.1 - 0.03 14.4 0.1 13 5.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFO96767.1 - 0.032 13.9 1.0 0.11 12.2 0.0 2.3 3 0 0 3 3 2 0 Archaeal ATPase KaiC PF06745.8 KFO96767.1 - 0.034 13.2 0.1 5.7 5.9 0.0 2.5 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.13 KFO96767.1 - 0.078 12.4 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KFO96767.1 - 5.7 7.7 4.6 9.1 7.1 0.4 2.9 3 0 0 3 3 2 0 AAA domain IRK PF01007.15 KFO96768.1 - 1.6e-156 520.3 0.1 1.9e-156 520.0 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFO96768.1 - 0.018 14.7 1.5 0.018 14.7 1.0 2.2 2 0 0 2 2 2 0 Ion channel Cupin_2 PF07883.6 KFO96768.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Cupin domain EF-hand_7 PF13499.1 KFO96769.1 - 2.3e-10 40.4 12.8 2.3e-10 40.4 8.8 3.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KFO96769.1 - 1.5e-09 36.4 2.8 0.00024 20.1 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFO96769.1 - 4.9e-06 25.9 4.2 0.00012 21.6 0.4 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KFO96769.1 - 0.00095 18.4 4.5 0.0055 16.0 0.3 4.1 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KFO96769.1 - 1.7 8.3 9.6 3 7.5 0.0 3.9 5 0 0 5 5 5 0 EF-hand domain pair DUF3186 PF11382.3 KFO96769.1 - 9.5 5.2 7.6 18 4.3 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) PI3_PI4_kinase PF00454.22 KFO96770.1 - 3.7e-54 183.6 0.1 7e-54 182.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFO96770.1 - 1e-43 148.6 0.5 2e-43 147.7 0.4 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 KFO96770.1 - 1.5e-28 99.3 0.6 4.7e-28 97.7 0.1 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 KFO96770.1 - 6.4e-25 87.1 0.2 1.9e-24 85.6 0.1 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PX PF00787.19 KFO96770.1 - 5.2e-19 68.1 1.3 1.1e-18 67.0 0.3 2.1 2 0 0 2 2 2 1 PX domain C2 PF00168.25 KFO96770.1 - 1.5e-08 34.3 0.0 3.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ribosomal_S15 PF00312.17 KFO96771.1 - 3.6e-24 84.3 0.3 7.7e-24 83.2 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S13_N PF08069.7 KFO96771.1 - 3.5e-16 58.7 0.3 7.4e-16 57.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain PAX PF00292.13 KFO96771.1 - 0.021 14.5 0.0 0.05 13.3 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain PH PF00169.24 KFO96772.1 - 5e-15 55.5 0.0 1.7e-14 53.8 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFO96772.1 - 2.6e-09 37.3 0.0 1.1e-08 35.3 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFO96772.1 - 2.3e-05 24.3 0.0 0.022 14.7 0.0 2.9 1 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KFO96772.1 - 0.0014 18.7 0.2 0.017 15.2 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain HMG_box_5 PF14887.1 KFO96772.1 - 0.13 12.0 5.3 0.057 13.1 0.9 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box 5 SMAP PF15477.1 KFO96773.1 - 3.1e-18 65.7 2.6 3.1e-18 65.7 1.8 2.5 2 1 0 2 2 2 1 Small acidic protein family RNA_polI_A34 PF08208.6 KFO96773.1 - 0.27 10.8 16.3 0.053 13.1 8.6 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.7 KFO96773.1 - 0.35 8.7 16.9 0.4 8.5 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family AF-4 PF05110.8 KFO96773.1 - 0.38 8.5 16.9 0.43 8.3 11.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF572 PF04502.8 KFO96773.1 - 0.63 9.1 15.0 0.83 8.8 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_phi PF04931.8 KFO96773.1 - 0.8 7.3 15.5 0.93 7.1 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM60A PF15396.1 KFO96773.1 - 0.99 9.1 6.9 1.2 8.8 4.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.9 KFO96773.1 - 1.1 7.1 13.7 1.3 6.9 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FCP1_C PF09309.5 KFO96773.1 - 1.4 8.1 19.8 1.9 7.7 13.6 1.5 1 1 0 1 1 1 0 FCP1, C-terminal PIG-S PF10510.4 KFO96773.1 - 1.6 7.3 5.6 1.9 7.0 3.9 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein RR_TM4-6 PF06459.7 KFO96773.1 - 2.6 7.8 13.3 3.2 7.5 9.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.7 KFO96773.1 - 2.7 7.1 9.6 3 6.9 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein Na_trans_assoc PF06512.8 KFO96773.1 - 2.7 7.9 13.4 3.3 7.6 9.3 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Hid1 PF12722.2 KFO96773.1 - 7 4.1 11.0 7.6 4.0 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.8 KFO96773.1 - 9.2 4.6 9.5 11 4.4 6.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HMG_box PF00505.14 KFO96774.1 - 2.1e-22 79.1 4.3 6.8e-22 77.5 3.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO96774.1 - 6.8e-09 35.9 1.0 6.8e-09 35.9 0.7 3.2 3 0 0 3 3 3 1 HMG-box domain AAA_23 PF13476.1 KFO96774.1 - 1.2 9.3 12.8 6.4 7.0 8.5 2.2 2 0 0 2 2 2 0 AAA domain OmpH PF03938.9 KFO96774.1 - 6.3 6.7 25.4 3.2 7.6 0.1 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Arm PF00514.18 KFO96775.1 - 0.00051 19.7 8.9 0.0044 16.7 0.2 5.3 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat Calc_CGRP_IAPP PF00214.14 KFO96776.1 - 1.7e-45 154.2 0.3 1.9e-45 154.0 0.2 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family DUF1615 PF07759.7 KFO96776.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) p450 PF00067.17 KFO96777.1 - 1.6e-114 383.0 0.0 1.8e-114 382.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_primase_S PF01896.14 KFO96777.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit Mlp PF03304.8 KFO96777.1 - 0.068 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Mlp lipoprotein family PDEase_I PF00233.14 KFO96778.1 - 2.1e-52 178.2 0.2 3.4e-48 164.4 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Adaptin_N PF01602.15 KFO96779.1 - 1.6e-121 406.2 9.1 2.3e-121 405.6 6.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KFO96779.1 - 2.1e-64 215.1 0.0 4.4e-64 214.0 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KFO96779.1 - 3.3e-62 208.3 0.2 8.3e-62 206.9 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KFO96779.1 - 3.3e-11 43.3 4.7 0.00039 20.6 0.0 6.0 3 1 2 6 6 6 2 HEAT repeats HEAT PF02985.17 KFO96779.1 - 8.9e-08 31.5 0.1 0.017 15.1 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KFO96779.1 - 4.4e-06 27.0 0.7 0.041 14.3 0.0 5.0 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 KFO96779.1 - 5.1e-05 23.2 11.6 0.062 13.1 0.0 4.7 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KFO96779.1 - 0.00016 21.3 0.1 2.6 7.9 0.0 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 KFO96779.1 - 0.00024 20.4 0.1 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Ras PF00071.17 KFO96780.1 - 3e-49 166.5 0.3 3.4e-49 166.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO96780.1 - 2.4e-12 47.3 0.0 5.1e-12 46.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFO96780.1 - 6.5e-07 28.9 0.0 8.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFO96780.1 - 3.5e-06 26.3 0.1 4e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 KFO96780.1 - 0.0049 16.4 0.0 0.006 16.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Tub PF01167.13 KFO96781.1 - 4.8e-66 222.2 0.2 4.8e-66 222.2 0.1 2.6 2 1 0 2 2 2 1 Tub family RIC3 PF15361.1 KFO96782.1 - 2.3e-37 128.5 0.0 4.5e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 LIM PF00412.17 KFO96783.1 - 1.8e-30 104.7 22.0 2.4e-15 56.3 5.8 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 KFO96783.1 - 3.9 7.5 22.2 0.36 10.8 4.6 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Bromodomain PF00439.20 KFO96784.1 - 1.2e-14 54.0 0.1 5.6e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 Bromodomain zf-B_box PF00643.19 KFO96784.1 - 1.4e-09 37.7 29.9 5.2e-09 35.8 7.3 5.4 6 1 0 6 6 6 2 B-box zinc finger PHD PF00628.24 KFO96784.1 - 6.8e-08 32.0 7.8 6.8e-08 32.0 5.4 4.4 4 0 0 4 4 4 1 PHD-finger Ribosomal_L18e PF00828.14 KFO96785.1 - 1.5e-37 128.8 0.5 1.6e-37 128.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RTC4 PF14474.1 KFO96785.1 - 0.18 11.7 0.4 3.6 7.5 0.1 2.1 1 1 0 2 2 2 0 RTC4-like domain HLH PF00010.21 KFO96786.1 - 4.5e-16 58.2 2.4 6.5e-16 57.7 1.7 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tmemb_9 PF05434.6 KFO96787.1 - 2e-63 212.6 6.5 4.1e-63 211.5 4.5 1.5 1 1 0 1 1 1 1 TMEM9 Asp_protease PF09668.5 KFO96788.1 - 2.7e-11 43.0 0.0 4.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KFO96788.1 - 4.3e-08 32.8 0.1 1.4e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KFO96788.1 - 4.5e-06 27.0 0.0 2e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KFO96788.1 - 0.07 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease FXa_inhibition PF14670.1 KFO96789.1 - 8.5e-68 224.1 158.8 1e-11 44.7 7.0 11.0 10 1 0 10 10 10 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFO96789.1 - 3.7e-34 115.9 67.5 9.2e-08 31.5 0.4 10.1 10 0 0 10 10 10 7 Complement Clr-like EGF-like EGF_CA PF07645.10 KFO96789.1 - 3.2e-27 94.2 156.4 2.8e-07 30.4 7.3 10.7 10 0 0 10 10 10 7 Calcium-binding EGF domain GCC2_GCC3 PF07699.8 KFO96789.1 - 3e-23 81.1 17.6 3.5e-13 48.8 5.5 4.7 4 0 0 4 4 4 2 GCC2 and GCC3 EGF_3 PF12947.2 KFO96789.1 - 6.6e-21 73.9 138.1 1.3e-08 34.6 5.1 10.6 9 0 0 9 9 9 8 EGF domain EGF PF00008.22 KFO96789.1 - 5.4e-20 71.0 133.5 4.2e-05 23.4 3.8 11.0 11 0 0 11 11 11 9 EGF-like domain CUB PF00431.15 KFO96789.1 - 1.1e-19 70.5 0.2 4.7e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 CUB domain DENN PF02141.16 KFO96790.1 - 1.4e-60 204.1 5.3 2.5e-60 203.3 3.1 1.8 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.14 KFO96790.1 - 3.6e-38 130.3 7.2 9.5e-19 67.4 1.1 2.8 3 0 0 3 3 3 2 RUN domain uDENN PF03456.13 KFO96790.1 - 2.5e-20 72.2 0.5 6.9e-20 70.7 0.1 2.1 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 KFO96790.1 - 4.8e-20 71.3 4.5 4.8e-20 71.3 3.1 2.3 2 0 0 2 2 2 1 dDENN domain PLAT PF01477.18 KFO96790.1 - 5.6e-16 58.9 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain SNARE_assoc PF09335.6 KFO96791.1 - 2.1e-23 82.8 6.3 2.1e-23 82.8 4.4 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein IncA PF04156.9 KFO96791.1 - 0.042 13.4 3.1 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 IncA protein DUF3357 PF11837.3 KFO96791.1 - 0.1 12.4 0.2 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) zf-H2C2_2 PF13465.1 KFO96792.1 - 9.4e-42 139.3 50.4 3.6e-09 36.4 0.4 7.6 7 0 0 7 7 7 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFO96792.1 - 8.5e-28 94.9 47.7 8.1e-06 25.8 0.8 7.4 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96792.1 - 1.8e-21 74.8 39.4 0.0046 17.2 0.4 7.3 7 0 0 7 7 7 7 C2H2-type zinc finger CopK PF11525.3 KFO96792.1 - 2.4e-05 23.8 3.0 6 6.5 0.0 5.4 4 2 2 6 6 6 2 Copper resistance protein K zf-C2H2_jaz PF12171.3 KFO96792.1 - 0.00017 21.6 25.7 3.3 7.9 0.5 7.4 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KFO96792.1 - 0.0038 17.5 1.0 0.0038 17.5 0.7 3.9 3 1 1 4 4 4 1 TRAF-type zinc finger Pkinase PF00069.20 KFO96793.1 - 1.6e-46 158.5 0.0 2.1e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96793.1 - 1.8e-21 76.3 0.0 2.2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KFO96794.1 - 1.7e-17 63.5 0.8 1.7e-17 63.5 0.6 2.0 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 KFO96794.1 - 3.7e-05 23.9 13.1 0.00015 21.9 2.6 3.8 2 2 1 3 3 3 1 Pleckstrin homology domain Herpes_US12 PF05363.7 KFO96796.1 - 0.017 15.6 17.3 64 4.1 0.1 6.7 7 0 0 7 7 7 0 Herpesvirus US12 family Calc_CGRP_IAPP PF00214.14 KFO96797.1 - 3.5e-33 114.4 0.0 3.9e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family A_deaminase PF00962.17 KFO96798.1 - 2.5e-125 417.8 0.3 3.5e-125 417.3 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-C3HC4_3 PF13920.1 KFO96799.1 - 9.3e-11 41.2 10.7 1.5e-10 40.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO96799.1 - 1.1e-10 41.1 13.3 2.1e-10 40.2 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFO96799.1 - 2.2e-07 30.7 14.0 4.1e-07 29.9 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO96799.1 - 1.1e-06 28.1 12.5 2.1e-06 27.2 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO96799.1 - 6e-05 22.6 14.6 0.00027 20.6 9.7 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFO96799.1 - 8.9e-05 21.9 5.7 0.00017 21.0 4.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KFO96799.1 - 0.00043 19.9 7.0 0.00082 19.0 3.0 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KFO96799.1 - 0.0014 18.7 14.7 0.0093 16.0 10.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KFO96799.1 - 0.034 14.0 12.6 0.079 12.8 8.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Sulfotransfer_2 PF03567.9 KFO96799.1 - 0.049 13.3 0.2 0.085 12.5 0.0 1.5 2 0 0 2 2 2 0 Sulfotransferase family zf-RING_4 PF14570.1 KFO96799.1 - 0.29 10.7 11.8 0.61 9.7 8.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KFO96799.1 - 0.4 10.5 9.3 0.82 9.5 5.9 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 KFO96799.1 - 1.1 8.7 7.8 0.49 9.9 0.3 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif Xlink PF00193.12 KFO96800.1 - 1.2e-19 70.1 0.2 2.2e-19 69.3 0.2 1.4 1 0 0 1 1 1 1 Extracellular link domain DUF4446 PF14584.1 KFO96800.1 - 0.0011 18.7 0.1 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) MGC-24 PF05283.6 KFO96800.1 - 0.0012 18.7 4.1 0.0012 18.7 2.9 1.6 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) Folate_carrier PF01770.13 KFO96800.1 - 0.027 13.0 0.3 0.038 12.5 0.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier OSTbeta PF15048.1 KFO96800.1 - 0.029 14.4 1.1 0.076 13.0 0.8 1.6 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein vMSA PF00695.14 KFO96800.1 - 0.032 13.4 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF2149 PF09919.4 KFO96800.1 - 0.13 12.3 0.2 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF3753 PF12575.3 KFO96800.1 - 0.64 9.8 4.0 5.2 6.9 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) OAD_gamma PF04277.8 KFO96800.1 - 5.3 7.4 7.9 33 4.9 5.5 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MRVI1 PF05781.7 KFO96801.1 - 4e-162 540.3 14.3 5.4e-162 539.9 9.9 1.1 1 0 0 1 1 1 1 MRVI1 protein DUF4471 PF14740.1 KFO96801.1 - 0.0084 15.3 3.7 0.018 14.3 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF2799 PF10973.3 KFO96801.1 - 0.45 10.5 5.2 0.24 11.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2799) TPR_11 PF13414.1 KFO96802.1 - 5.8e-46 154.0 35.5 2.6e-09 36.5 0.2 11.7 5 4 7 13 13 13 12 TPR repeat TPR_1 PF00515.23 KFO96802.1 - 1.1e-42 141.9 39.2 7.9e-05 22.0 0.1 13.4 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_2 PF07719.12 KFO96802.1 - 1.5e-39 130.7 47.5 8.2e-05 22.2 0.0 15.5 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFO96802.1 - 1.7e-37 127.2 24.1 1.2e-06 29.0 0.2 11.5 8 2 3 11 11 11 8 Tetratricopeptide repeat TPR_19 PF14559.1 KFO96802.1 - 4.8e-35 119.7 16.5 1e-05 25.7 0.0 11.3 7 3 3 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.1 KFO96802.1 - 3e-34 116.7 39.0 2e-07 30.8 0.9 10.1 4 2 7 11 11 11 10 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96802.1 - 8.9e-34 112.8 16.8 0.0048 17.4 0.0 14.7 7 4 8 15 15 15 7 Tetratricopeptide repeat TPR_17 PF13431.1 KFO96802.1 - 1.6e-26 90.2 26.3 0.098 12.9 0.2 15.7 18 0 0 18 18 17 8 Tetratricopeptide repeat TPR_8 PF13181.1 KFO96802.1 - 9.8e-21 71.9 31.7 0.0034 17.0 0.0 12.6 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_6 PF13174.1 KFO96802.1 - 2.4e-16 58.9 40.5 0.0043 17.4 0.0 14.5 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFO96802.1 - 1.2e-13 50.5 21.8 0.0044 16.9 0.1 13.0 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFO96802.1 - 8.5e-13 47.0 33.8 0.034 13.9 0.1 13.0 13 2 1 14 14 14 5 Tetratricopeptide repeat Apc3 PF12895.2 KFO96802.1 - 1.4e-09 37.9 42.8 9.2e-05 22.5 5.0 7.9 6 3 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPPII_N PF12583.3 KFO96802.1 - 6.9e-06 26.2 1.8 0.051 13.7 0.0 4.6 4 0 0 4 4 4 1 Tripeptidyl peptidase II N terminal TPR_9 PF13371.1 KFO96802.1 - 2.4e-05 24.1 5.8 0.086 12.6 0.0 5.8 5 1 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 KFO96802.1 - 9.7e-05 21.3 2.5 9.7e-05 21.3 1.8 6.1 5 1 1 7 7 4 1 NMDA receptor-regulated protein 1 MIF4G PF02854.14 KFO96803.1 - 1.8e-57 194.1 2.4 1.8e-57 194.1 1.6 2.3 2 0 0 2 2 2 1 MIF4G domain W2 PF02020.13 KFO96803.1 - 2.6e-21 75.3 1.3 2.8e-20 72.0 1.0 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon MA3 PF02847.12 KFO96803.1 - 6.8e-17 61.1 5.3 1.1e-16 60.5 0.1 3.0 3 0 0 3 3 3 1 MA3 domain Glycos_transf_2 PF00535.21 KFO96806.1 - 7.6e-23 81.0 0.1 1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFO96806.1 - 1.2e-06 28.5 0.1 0.041 13.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFO96806.1 - 7.7e-06 25.1 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFO96806.1 - 8.4e-06 25.1 0.0 1.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase UCH PF00443.24 KFO96807.1 - 2.2e-58 197.5 1.4 5.4e-58 196.2 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO96807.1 - 2.1e-32 112.7 0.3 2.1e-32 112.7 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.1 KFO96807.1 - 4.7e-08 33.1 0.3 0.084 13.1 0.0 4.2 4 0 0 4 4 4 3 Ubiquitin-like domain ubiquitin PF00240.18 KFO96807.1 - 3.3e-07 29.6 0.2 0.095 12.1 0.0 3.8 3 0 0 3 3 3 2 Ubiquitin family CP2 PF04516.10 KFO96807.1 - 0.26 10.3 6.6 0.38 9.7 1.0 2.5 2 0 0 2 2 2 0 CP2 transcription factor Dickkopf_N PF04706.7 KFO96808.1 - 3.7e-18 65.3 20.3 3.7e-18 65.3 14.1 3.1 3 0 0 3 3 3 1 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.6 KFO96808.1 - 1.1e-05 25.4 3.2 1.1e-05 25.4 2.2 2.8 1 1 2 3 3 3 1 Prokineticin CH PF00307.26 KFO96809.1 - 1.6e-25 89.2 1.3 2.3e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFO96809.1 - 5.4e-06 25.9 0.0 0.088 12.4 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain FlaG PF03646.10 KFO96809.1 - 0.037 14.1 0.6 0.11 12.7 0.4 1.7 1 0 0 1 1 1 0 FlaG protein SYCE1 PF15233.1 KFO96809.1 - 2.6 7.9 8.1 0.32 10.9 1.7 2.1 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 TEA PF01285.13 KFO96810.1 - 2.5e-179 596.9 0.0 3e-179 596.7 0.0 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 KFO96810.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain PAS_11 PF14598.1 KFO96811.1 - 1.2e-27 96.1 0.2 1.1e-22 80.1 0.1 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFO96811.1 - 3.8e-20 71.7 0.0 8.4e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 KFO96811.1 - 3.7e-17 62.2 0.0 5.1e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFO96811.1 - 6.4e-17 60.9 0.7 1.1e-16 60.2 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFO96811.1 - 1.5e-09 38.1 0.0 0.0028 17.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFO96811.1 - 2.6e-05 24.2 0.0 0.0085 16.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_2 PF08446.6 KFO96811.1 - 0.085 13.3 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 PAS fold BTB_2 PF02214.17 KFO96812.1 - 0.00059 19.9 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Parathyroid PF01279.12 KFO96813.1 - 1.1e-21 77.3 2.8 1.5e-21 76.8 1.9 1.2 1 0 0 1 1 1 1 Parathyroid hormone family DUF4224 PF13986.1 KFO96813.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) NAD_binding_4 PF07993.7 KFO96814.1 - 5.5e-75 251.4 0.0 7.2e-75 251.1 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.14 KFO96814.1 - 1.2e-22 79.9 1.2 3.1e-22 78.6 0.8 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KFO96814.1 - 7.6e-09 35.3 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFO96814.1 - 8.8e-05 21.3 0.0 0.02 13.6 0.0 2.8 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KFO96814.1 - 0.00078 18.4 0.0 0.0021 16.9 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KFO96814.1 - 0.036 14.3 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KFO96814.1 - 0.043 13.8 0.0 2 8.3 0.0 3.3 2 1 0 2 2 2 0 NADH(P)-binding DapB_N PF01113.15 KFO96814.1 - 0.074 12.9 0.0 0.74 9.7 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_1 PF00175.16 KFO96815.1 - 1.2e-33 115.9 0.0 3.3e-33 114.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFO96815.1 - 1.6e-33 114.7 0.0 2.8e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFO96815.1 - 8.9e-06 25.6 0.0 0.00013 21.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFO96815.1 - 0.0047 16.8 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SAM_1 PF00536.25 KFO96816.1 - 2.1e-40 136.6 6.0 1.6e-18 66.5 0.0 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFO96816.1 - 2e-39 133.2 3.9 7.8e-15 54.4 0.0 3.9 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) Integrase_DNA PF02920.10 KFO96816.1 - 1e-20 72.8 10.9 2.4e-20 71.6 7.6 1.7 1 0 0 1 1 1 1 DNA binding domain of tn916 integrase Reo_sigmaC PF04582.7 KFO96816.1 - 0.017 14.3 6.9 0.04 13.0 2.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SAM_PNT PF02198.11 KFO96816.1 - 0.1 12.4 3.9 3.9 7.2 0.1 3.4 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain ADIP PF11559.3 KFO96816.1 - 0.15 11.9 29.3 0.89 9.4 12.5 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 KFO96816.1 - 0.61 10.8 15.9 0.43 11.3 3.2 2.8 1 1 1 2 2 2 0 Occludin homology domain zf-C4H2 PF10146.4 KFO96816.1 - 6.8 6.6 12.9 15 5.5 9.0 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein V_ATPase_I PF01496.14 KFO96816.1 - 7.1 4.3 12.2 10 3.8 8.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 KFO96816.1 - 9.3 5.9 24.6 0.31 10.7 4.9 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 M_domain PF12938.2 KFO96816.1 - 9.7 5.9 10.0 4.4 7.0 4.7 2.0 2 0 0 2 2 2 0 M domain of GW182 IncA PF04156.9 KFO96816.1 - 9.8 5.7 42.9 4.9 6.7 9.8 2.4 1 1 1 2 2 2 0 IncA protein Mab-21 PF03281.9 KFO96817.1 - 5.8e-13 48.6 4.9 1.3e-11 44.2 2.0 2.2 1 1 0 2 2 2 2 Mab-21 protein C2 PF00168.25 KFO96818.1 - 1.6e-57 191.2 0.2 4.2e-29 100.2 0.1 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 KFO96818.1 - 0.019 14.5 0.0 2.9 7.3 0.0 2.6 3 0 0 3 3 3 0 CEP76 C2 domain NT-C2 PF10358.4 KFO96818.1 - 0.083 12.3 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins TSP_1 PF00090.14 KFO96819.1 - 2e-82 271.0 94.1 4.7e-17 61.8 4.9 7.0 7 0 0 7 7 7 6 Thrombospondin type 1 domain Spond_N PF06468.8 KFO96819.1 - 3.5e-79 265.0 0.2 6.3e-79 264.2 0.2 1.4 1 0 0 1 1 1 1 Spondin_N Reeler PF02014.11 KFO96819.1 - 2.6e-32 111.8 0.0 4.8e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Reeler domain DUF3827 PF12877.2 KFO96820.1 - 3e-259 861.7 7.5 3e-259 861.7 5.2 2.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3827) Shisa PF13908.1 KFO96820.1 - 2.8 8.0 5.5 0.65 10.1 0.1 2.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Pkinase PF00069.20 KFO96821.1 - 9.5e-51 172.4 0.0 1.8e-50 171.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96821.1 - 1.1e-23 83.6 0.0 1.9e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO96821.1 - 8.9e-06 24.9 0.0 1.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO96821.1 - 0.0022 17.7 0.1 0.0055 16.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFO96821.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family CLAMP PF14769.1 KFO96821.1 - 0.09 12.9 1.3 0.31 11.2 0.0 2.6 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 DUF4519 PF15012.1 KFO96821.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Suf PF05843.9 KFO96822.1 - 3.5e-87 292.6 2.8 4.3e-84 282.5 0.0 4.0 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KFO96822.1 - 0.00011 22.5 0.7 0.13 12.9 0.0 4.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO96822.1 - 0.00091 19.8 0.7 0.0082 16.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO96822.1 - 0.0035 17.6 0.4 0.17 12.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO96822.1 - 0.013 15.9 5.2 0.071 13.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KFO96822.1 - 0.028 13.2 17.9 0.8 8.5 3.1 5.5 2 1 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 KFO96822.1 - 0.052 13.1 9.1 2.9 7.6 2.1 3.6 2 1 1 3 3 3 0 TPR repeat HAT PF02184.11 KFO96822.1 - 6.1 6.6 7.5 10 5.9 0.0 4.5 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat Tcp11 PF05794.8 KFO96823.1 - 4.6e-130 434.2 0.0 5.3e-130 434.0 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF1819 PF08849.6 KFO96823.1 - 0.031 13.6 0.2 0.071 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) EF_TS PF00889.14 KFO96823.1 - 0.13 11.6 0.0 0.65 9.2 0.0 2.0 2 0 0 2 2 2 0 Elongation factor TS DEP PF00610.16 KFO96824.1 - 2.9e-15 55.7 1.4 1.3e-14 53.6 0.1 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SMC_N PF02463.14 KFO96824.1 - 0.14 11.3 0.6 0.34 10.1 0.1 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Gla PF00594.15 KFO96825.1 - 1.1e-13 50.5 6.8 2.2e-13 49.6 4.7 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF1810 PF08837.6 KFO96825.1 - 0.0098 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1810) WBP-1 PF11669.3 KFO96825.1 - 0.036 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 IncA PF04156.9 KFO96825.1 - 0.051 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 IncA protein TMEM190 PF15431.1 KFO96825.1 - 0.053 13.4 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 ETRAMP PF09716.5 KFO96825.1 - 0.063 13.2 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CD34_antigen PF06365.7 KFO96825.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.1 KFO96825.1 - 0.12 12.8 0.0 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UPF0560 PF10577.4 KFO96825.1 - 0.13 10.4 0.1 0.18 10.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Death PF00531.17 KFO96826.1 - 0.085 12.6 0.1 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Death domain WT1 PF02165.10 KFO96827.1 - 6.8e-164 543.9 10.4 8.5e-164 543.6 7.2 1.1 1 0 0 1 1 1 1 Wilm's tumour protein zf-H2C2_2 PF13465.1 KFO96827.1 - 1.5e-15 56.6 40.2 3.4e-07 30.2 1.9 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFO96827.1 - 2.3e-15 55.9 39.0 2.1e-05 24.5 2.3 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96827.1 - 1.5e-08 34.3 32.8 0.00083 19.5 1.6 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFO96827.1 - 0.026 14.7 2.3 0.026 14.7 1.6 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ofd1_CTDD PF10637.4 KFO96827.1 - 0.17 10.9 2.5 0.2 10.7 0.9 1.6 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term zinc_ribbon_4 PF13717.1 KFO96827.1 - 0.56 9.9 3.8 40 4.0 0.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain CCAP PF11105.3 KFO96827.1 - 3.5 7.3 6.1 0.62 9.7 0.2 2.2 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a EF-hand_7 PF13499.1 KFO96828.1 - 2.6e-20 72.2 16.1 5.1e-09 36.1 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFO96828.1 - 3.8e-19 66.4 15.2 0.0027 16.9 0.7 6.7 6 0 0 6 6 6 6 EF hand EF-hand_6 PF13405.1 KFO96828.1 - 1.5e-16 58.7 15.2 0.0052 16.5 0.0 6.5 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.1 KFO96828.1 - 2.9e-10 39.0 25.4 0.00053 19.2 0.4 6.7 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.1 KFO96828.1 - 1.6e-07 30.8 15.1 0.017 14.7 0.4 6.2 6 1 0 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO96828.1 - 0.0017 18.3 9.2 0.18 11.8 0.1 3.6 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region DUF2852 PF11014.3 KFO96828.1 - 0.42 10.5 5.7 0.82 9.6 1.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) EF-hand_4 PF12763.2 KFO96828.1 - 7 6.4 11.8 6.1 6.6 0.2 4.4 4 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand PAX PF00292.13 KFO96829.1 - 1.1e-43 147.9 0.2 2.2e-43 146.9 0.2 1.5 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 KFO96829.1 - 3.4e-23 81.0 4.5 5.7e-23 80.3 3.1 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_32 PF13565.1 KFO96829.1 - 0.04 14.7 1.2 0.9 10.3 0.0 2.5 2 1 0 2 2 2 0 Homeodomain-like domain Homeobox_KN PF05920.6 KFO96829.1 - 0.086 12.5 1.1 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain PAXNEB PF05625.6 KFO96830.1 - 8.2e-91 304.5 0.1 9.1e-91 304.3 0.1 1.0 1 0 0 1 1 1 1 PAXNEB protein Peptidase_S24 PF00717.18 KFO96831.1 - 7.2e-14 51.1 0.0 1.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KFO96831.1 - 1.5e-07 30.9 0.0 0.00031 20.2 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DnaJ PF00226.26 KFO96832.1 - 3.1e-19 68.4 0.5 4.2e-19 68.0 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 KFO96832.1 - 4.4e-12 45.3 6.0 7.2e-12 44.6 4.1 1.4 1 0 0 1 1 1 1 CSL zinc finger fn1 PF00039.13 KFO96832.1 - 0.038 13.7 1.7 0.099 12.4 1.2 1.6 1 0 0 1 1 1 0 Fibronectin type I domain Metallophos PF00149.23 KFO96834.1 - 3.3e-09 36.4 2.5 7.7e-09 35.2 1.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFO96834.1 - 9e-06 25.6 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ARF7EP_C PF14949.1 KFO96835.1 - 8.2e-37 125.8 5.9 2e-36 124.6 4.1 1.7 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Cys_knot PF00007.17 KFO96836.1 - 4.2e-31 107.1 18.5 5.2e-31 106.8 12.8 1.1 1 0 0 1 1 1 1 Cystine-knot domain Ion_trans PF00520.26 KFO96837.1 - 7e-34 116.8 6.7 7e-34 116.8 4.7 1.8 2 0 0 2 2 2 1 Ion transport protein K_channel_TID PF07941.6 KFO96837.1 - 6.9e-33 112.7 16.7 1.3e-32 111.8 11.6 1.5 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain BTB_2 PF02214.17 KFO96837.1 - 9.4e-28 96.2 0.0 2.3e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFO96837.1 - 2.8e-13 49.3 5.0 2.8e-13 49.3 3.5 2.2 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFO96837.1 - 0.00093 17.7 0.4 0.00093 17.7 0.3 1.8 1 1 1 2 2 2 1 Polycystin cation channel Methyltransf_5 PF01795.14 KFO96838.1 - 7.9e-81 271.7 0.0 1.1e-79 268.0 0.0 1.9 1 1 0 1 1 1 1 MraW methylase family Methyltransf_18 PF12847.2 KFO96838.1 - 2.2e-05 24.9 0.0 0.0039 17.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFO96838.1 - 9.3e-05 22.4 0.0 0.00074 19.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO96838.1 - 0.00063 19.3 0.0 0.47 10.0 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KFO96838.1 - 0.0021 18.5 0.0 0.22 12.0 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO96838.1 - 0.023 15.1 0.0 1.2 9.6 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_15 PF09445.5 KFO96838.1 - 0.031 13.8 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Kinesin PF00225.18 KFO96839.1 - 1.8e-113 378.6 0.8 1.8e-113 378.6 0.5 3.1 2 1 1 3 3 3 1 Kinesin motor domain DUF2443 PF10398.4 KFO96839.1 - 0.27 11.0 4.7 1.5 8.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2443) NGF PF00243.13 KFO96840.1 - 5.2e-59 197.0 3.5 7.2e-59 196.6 2.4 1.2 1 0 0 1 1 1 1 Nerve growth factor family PDZ PF00595.19 KFO96841.1 - 2.9e-21 75.4 0.6 4.3e-21 74.8 0.4 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) L27 PF02828.11 KFO96841.1 - 1.2e-20 72.8 0.2 2.3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 L27 domain PDZ_2 PF13180.1 KFO96841.1 - 0.00057 19.7 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF2057 PF09829.4 KFO96841.1 - 0.0039 16.8 0.5 0.0097 15.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) LRR_8 PF13855.1 KFO96842.1 - 1.3e-113 370.7 99.6 1.9e-16 59.5 1.2 8.6 1 1 13 14 14 14 14 Leucine rich repeat LRR_5 PF13306.1 KFO96842.1 - 1e-42 144.8 0.0 1.2e-12 47.6 0.0 4.2 1 1 4 5 5 5 5 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFO96842.1 - 2e-41 138.9 43.2 1.5e-09 37.2 0.1 10.4 3 3 8 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO96842.1 - 1.1e-33 109.9 31.8 0.0047 16.7 0.1 14.7 15 0 0 15 15 15 12 Leucine Rich Repeat LRR_7 PF13504.1 KFO96842.1 - 7.2e-17 58.5 29.7 0.74 10.2 0.1 14.3 15 0 0 15 15 15 5 Leucine rich repeat 7tm_1 PF00001.16 KFO96842.1 - 9.8e-17 60.9 11.3 1.5e-16 60.3 7.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_9 PF14580.1 KFO96842.1 - 1.5e-10 40.9 5.0 0.0029 17.1 0.1 3.8 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 KFO96842.1 - 2.2e-10 39.4 36.5 0.41 10.8 0.0 13.1 12 1 1 13 13 13 5 Leucine Rich repeat Sigma70_r4 PF04545.11 KFO96842.1 - 0.057 12.7 0.1 0.14 11.4 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4207 PF13904.1 KFO96843.1 - 5.3e-33 114.5 42.5 6.5e-33 114.2 29.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) Borrelia_P83 PF05262.6 KFO96843.1 - 0.0014 16.9 23.4 0.0015 16.9 16.2 1.0 1 0 0 1 1 1 1 Borrelia P83/100 protein N6_N4_Mtase PF01555.13 KFO96843.1 - 0.23 10.8 10.9 0.26 10.7 7.6 1.1 1 0 0 1 1 1 0 DNA methylase Neur_chan_memb PF02932.11 KFO96843.1 - 0.54 10.0 8.5 0.61 9.9 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TauD PF02668.11 KFO96844.1 - 4.3e-48 164.2 0.0 5.6e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KFO96844.1 - 4.7e-11 42.9 0.3 2.5e-08 34.1 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.5 KFO96844.1 - 0.00028 19.8 0.0 0.00045 19.2 0.0 1.3 1 0 0 1 1 1 1 CsiD DUF2442 PF10387.4 KFO96844.1 - 0.08 12.9 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) SSF PF00474.12 KFO96846.1 - 2.7e-38 131.7 23.2 3.4e-38 131.3 16.1 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family NdhL PF10716.4 KFO96846.1 - 0.022 14.4 2.0 0.11 12.2 0.0 2.8 2 1 0 3 3 3 0 NADH dehydrogenase transmembrane subunit Yae1_N PF09811.4 KFO96847.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Leu_zip PF15294.1 KFO96848.1 - 2.2e-63 213.9 32.9 2.6e-63 213.7 22.8 1.0 1 0 0 1 1 1 1 Leucine zipper DUF4107 PF13389.1 KFO96848.1 - 0.0094 15.6 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4107) Reo_sigmaC PF04582.7 KFO96848.1 - 0.037 13.2 8.4 0.0096 15.1 1.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2119 PF09892.4 KFO96848.1 - 0.041 13.1 2.1 0.72 9.0 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) BAR PF03114.13 KFO96848.1 - 0.11 11.9 22.5 0.15 11.5 15.6 1.1 1 0 0 1 1 1 0 BAR domain Fib_alpha PF08702.5 KFO96848.1 - 0.15 12.1 22.6 0.91 9.6 3.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LAGLIDADG_1 PF00961.14 KFO96848.1 - 0.39 11.2 3.4 0.71 10.4 2.4 1.5 1 0 0 1 1 1 0 LAGLIDADG endonuclease FTCD_C PF04961.7 KFO96848.1 - 0.54 9.6 7.8 0.092 12.1 2.2 2.1 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DUF1612 PF07756.7 KFO96848.1 - 1.2 9.2 6.8 8.5 6.4 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1612) Cep57_CLD_2 PF14197.1 KFO96848.1 - 1.2 9.1 27.3 0.54 10.2 5.8 3.6 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF3584 PF12128.3 KFO96848.1 - 1.4 6.1 28.0 2 5.6 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SSFA2_C PF14723.1 KFO96848.1 - 1.8 8.2 13.9 0.63 9.7 5.9 2.2 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus Filament PF00038.16 KFO96848.1 - 3.5 7.0 30.2 8.5 5.7 1.5 2.8 1 1 1 2 2 2 0 Intermediate filament protein WEMBL PF05701.6 KFO96848.1 - 4.7 5.5 33.7 82 1.4 23.6 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 KFO96848.1 - 4.9 6.8 37.7 2.3 7.9 11.7 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TMEM192 PF14802.1 KFO96848.1 - 6.4 5.5 7.8 48 2.6 5.4 2.0 1 1 0 1 1 1 0 TMEM192 family Spc7 PF08317.6 KFO96848.1 - 7.4 5.1 34.9 1.1 7.9 14.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 KFO96848.1 - 8.6 5.7 36.9 3.3 7.1 3.9 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 Atg14 PF10186.4 KFO96848.1 - 8.7 5.1 27.8 0.41 9.5 13.6 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GAS2 PF02187.12 KFO96849.1 - 5.1e-36 122.2 0.2 8.6e-36 121.5 0.2 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 KFO96849.1 - 4.7e-08 33.0 0.0 7.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain FANCF PF11107.3 KFO96850.1 - 2.9e-61 207.6 0.0 4.5e-61 206.9 0.0 1.3 1 1 0 1 1 1 1 Fanconi anemia group F protein (FANCF) RFamide_26RFa PF11109.3 KFO96850.1 - 0.0091 15.9 0.5 0.017 14.9 0.1 1.6 2 0 0 2 2 2 1 Orexigenic neuropeptide Qrfp/P518 MFS_1 PF07690.11 KFO96851.1 - 2.8e-50 171.0 24.2 8.1e-49 166.2 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Anoctamin PF04547.7 KFO96852.1 - 2.4e-162 540.7 21.1 2.9e-162 540.4 14.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel EGF_CA PF07645.10 KFO96853.1 - 1.2e-26 92.4 54.0 2e-11 43.6 3.5 10.8 9 2 2 11 11 7 4 Calcium-binding EGF domain VWC PF00093.13 KFO96853.1 - 6.2e-16 58.2 76.3 3.1e-09 36.8 10.2 9.9 7 1 2 10 10 7 5 von Willebrand factor type C domain EGF_3 PF12947.2 KFO96853.1 - 7.1e-13 48.2 36.8 2e-09 37.2 9.5 11.0 10 0 0 10 10 8 4 EGF domain Laminin_G_2 PF02210.19 KFO96853.1 - 1.4e-09 38.0 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain cEGF PF12662.2 KFO96853.1 - 4.9e-09 35.6 11.2 2.5e-07 30.1 1.2 10.7 11 0 0 11 11 10 5 Complement Clr-like EGF-like EGF PF00008.22 KFO96853.1 - 1.3e-07 31.4 36.7 9.3e-05 22.3 3.0 10.8 13 1 0 13 13 9 4 EGF-like domain Laminin_G_3 PF13385.1 KFO96853.1 - 6.6e-07 29.6 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 KFO96853.1 - 4.2e-05 23.5 0.0 0.00011 22.2 0.0 1.6 1 1 0 1 1 1 1 Laminin G domain hEGF PF12661.2 KFO96853.1 - 0.00034 20.4 3.0 0.00034 20.4 2.1 11.9 12 0 0 12 12 10 2 Human growth factor-like EGF EGF_2 PF07974.8 KFO96853.1 - 0.002 18.2 14.2 0.002 18.2 9.8 13.1 10 3 1 11 11 10 2 EGF-like domain FXa_inhibition PF14670.1 KFO96853.1 - 0.018 15.1 7.5 0.018 15.1 5.2 10.9 8 3 2 10 10 6 0 Coagulation Factor Xa inhibitory site SNF PF00209.13 KFO96854.1 - 8.7e-123 410.5 17.3 9.7e-123 410.3 12.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PrmA PF06325.8 KFO96855.1 - 2.4e-11 43.2 0.0 4.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFO96855.1 - 1.4e-10 40.9 0.0 4.8e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO96855.1 - 3.2e-09 37.3 0.2 1.7e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO96855.1 - 1.9e-08 34.7 0.0 5.8e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFO96855.1 - 1.9e-08 33.3 0.0 2.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 KFO96855.1 - 1.4e-07 31.5 0.1 4.2e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFO96855.1 - 9.7e-07 28.3 0.0 2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 KFO96855.1 - 1.6e-06 27.3 0.1 3.1e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 KFO96855.1 - 1.6e-06 27.9 0.0 5.8e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO96855.1 - 6.2e-05 23.3 0.1 0.00021 21.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 KFO96855.1 - 0.00042 19.9 0.1 0.00086 18.9 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.12 KFO96855.1 - 0.00047 19.2 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 KFO96855.1 - 0.00055 20.3 0.0 0.0015 18.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFO96855.1 - 0.00057 19.9 0.0 0.0022 18.0 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase zf-C2H2_2 PF12756.2 KFO96855.1 - 0.0011 19.0 0.7 0.0034 17.4 0.5 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) TehB PF03848.9 KFO96855.1 - 0.003 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KFO96855.1 - 0.0071 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ATP-synt_B PF00430.13 KFO96855.1 - 0.0079 16.0 0.2 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Methyltransf_16 PF10294.4 KFO96855.1 - 0.032 13.6 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KFO96855.1 - 0.051 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1707 PF08044.6 KFO96855.1 - 0.057 13.1 2.0 0.11 12.2 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Homeobox PF00046.24 KFO96856.1 - 1.1e-21 76.1 3.5 1.9e-21 75.4 2.4 1.4 1 0 0 1 1 1 1 Homeobox domain DUF2986 PF11661.3 KFO96856.1 - 0.0021 18.3 1.1 0.0021 18.3 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homez PF11569.3 KFO96856.1 - 0.0056 15.7 0.2 0.011 14.8 0.2 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFO96856.1 - 0.081 12.6 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain E2F_TDP PF02319.15 KFO96857.1 - 3.7e-43 144.9 0.6 3e-21 74.7 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 KFO96857.1 - 0.00012 21.6 0.2 0.00048 19.7 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 KFO96857.1 - 0.016 15.0 0.4 7.7 6.4 0.0 3.0 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC LIM PF00412.17 KFO96858.1 - 4.6e-24 84.2 22.0 9.3e-17 60.8 3.1 2.4 2 1 0 2 2 2 2 LIM domain zf-TFIIB PF13453.1 KFO96858.1 - 0.044 12.9 4.3 1.3 8.2 0.0 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger Zn_ribbon_2 PF12674.2 KFO96858.1 - 0.14 12.5 10.9 1.1 9.6 2.0 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-C2H2_7 PF15269.1 KFO96858.1 - 0.27 11.1 4.9 6.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger zf-ribbon_3 PF13248.1 KFO96858.1 - 0.49 9.6 0.1 0.49 9.6 0.0 3.9 4 1 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFO96858.1 - 1.1 8.8 0.0 1.1 8.8 0.0 3.9 4 1 0 4 4 4 0 zinc-ribbon domain DUF329 PF03884.9 KFO96858.1 - 1.2 8.7 7.6 3.9 7.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF329) Papo_T_antigen PF02380.10 KFO96858.1 - 2.6 8.0 11.1 9.4 6.2 2.9 2.2 2 0 0 2 2 2 0 T-antigen specific domain Zn-ribbon_8 PF09723.5 KFO96858.1 - 5.9 6.9 18.6 2.5 8.1 0.0 4.1 4 1 0 4 4 4 0 Zinc ribbon domain zf-FPG_IleRS PF06827.9 KFO96858.1 - 6.5 6.5 11.6 1.5 8.5 0.1 3.8 4 1 0 4 4 4 0 Zinc finger found in FPG and IleRS ERG4_ERG24 PF01222.12 KFO96859.1 - 7.8e-93 311.3 28.9 9.6e-93 311.0 20.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF912 PF06024.7 KFO96859.1 - 0.025 14.6 0.0 0.082 12.9 0.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ICMT PF04140.9 KFO96859.1 - 0.028 14.6 2.2 0.042 14.0 0.1 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 KFO96859.1 - 0.77 9.0 10.4 0.024 13.9 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1295) CN_hydrolase PF00795.17 KFO96860.1 - 3.5e-32 111.2 0.0 6.8e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KFO96860.1 - 4e-28 97.9 0.0 1e-27 96.5 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KFO96860.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase TSC22 PF01166.13 KFO96862.1 - 2.4e-31 107.4 4.7 2.9e-31 107.2 3.2 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 KFO96862.1 - 0.00058 20.1 3.0 0.00067 19.9 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) MAD PF05557.8 KFO96862.1 - 0.00087 17.5 2.0 0.00095 17.3 1.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DivIC PF04977.10 KFO96862.1 - 0.0028 17.0 4.3 0.0028 17.0 3.0 1.3 1 1 0 1 1 1 1 Septum formation initiator Nnf1 PF03980.9 KFO96862.1 - 0.01 15.8 0.7 0.012 15.6 0.5 1.2 1 0 0 1 1 1 1 Nnf1 DUF904 PF06005.7 KFO96862.1 - 0.01 16.0 8.7 0.017 15.3 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF16 PF01519.11 KFO96862.1 - 0.011 15.9 2.5 0.013 15.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Lebercilin PF15619.1 KFO96862.1 - 0.013 14.9 2.5 0.015 14.7 1.7 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_2 PF07716.10 KFO96862.1 - 0.023 14.4 5.0 0.039 13.7 3.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF948 PF06103.6 KFO96862.1 - 0.032 14.0 0.9 0.039 13.8 0.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.8 KFO96862.1 - 0.057 12.8 1.6 0.061 12.7 1.1 1.0 1 0 0 1 1 1 0 fzo-like conserved region COG2 PF06148.6 KFO96862.1 - 0.074 12.9 1.6 0.1 12.4 1.1 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NYD-SP28_assoc PF14775.1 KFO96862.1 - 0.083 12.6 1.5 0.12 12.0 1.1 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_1 PF00170.16 KFO96862.1 - 0.11 12.4 5.4 0.14 12.1 3.5 1.4 1 1 0 1 1 1 0 bZIP transcription factor Shugoshin_N PF07558.6 KFO96862.1 - 0.2 11.4 2.9 0.38 10.4 2.0 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Cu-oxidase_4 PF02578.10 KFO96863.1 - 2.8e-62 209.8 0.0 3.8e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase UPF0058 PF01893.11 KFO96863.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0058 DUF904 PF06005.7 KFO96864.1 - 0.032 14.5 8.5 0.032 14.5 5.9 5.2 2 2 1 3 3 2 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 KFO96864.1 - 0.048 13.5 42.7 1.6 8.6 4.0 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KFO96864.1 - 0.1 12.2 39.8 0.37 10.3 3.6 3.3 1 1 2 3 3 3 0 IncA protein TMF_DNA_bd PF12329.3 KFO96864.1 - 0.21 11.4 37.5 0.26 11.1 0.4 4.5 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4094 PF13334.1 KFO96864.1 - 0.28 11.6 14.4 0.12 12.7 0.8 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DUF1192 PF06698.6 KFO96864.1 - 0.28 11.0 15.0 0.18 11.5 0.3 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) LINES_C PF14695.1 KFO96864.1 - 0.28 10.4 6.1 22 4.3 0.0 4.2 4 0 0 4 4 4 0 Lines C-terminus DUF2944 PF11161.3 KFO96864.1 - 0.41 10.2 3.4 0.17 11.5 0.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2946) DUF3095 PF11294.3 KFO96864.1 - 3.3 6.6 7.3 0.3 10.0 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3095) Syntaxin PF00804.20 KFO96864.1 - 3.3 7.9 23.4 2.4 8.3 5.2 3.7 2 2 1 3 3 3 0 Syntaxin ADIP PF11559.3 KFO96864.1 - 3.5 7.4 36.8 3.7 7.4 4.6 3.9 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 KFO96864.1 - 4.6 7.3 22.5 1.3 9.1 1.7 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1977 PF09320.6 KFO96864.1 - 4.8 7.4 10.4 0.09 13.0 1.6 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1977) FlxA PF14282.1 KFO96864.1 - 6.7 6.7 29.4 2.6 8.0 6.7 3.9 2 2 3 5 5 5 0 FlxA-like protein RRM_1 PF00076.17 KFO96865.1 - 8.8e-10 38.0 0.0 2.2e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96865.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFO96865.1 - 0.0082 15.8 0.1 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KFO96865.1 - 0.049 13.4 0.3 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TetR_C_7 PF14246.1 KFO96865.1 - 0.11 12.7 0.9 9.9 6.4 0.0 3.0 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region TBPIP PF07106.8 KFO96865.1 - 1.7 8.1 22.9 0.05 13.1 9.4 2.6 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DnaJ PF00226.26 KFO96866.1 - 1.7e-07 30.8 0.0 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain VWC PF00093.13 KFO96868.1 - 2.9e-09 36.8 53.2 7.3e-06 25.9 11.9 3.2 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.8 KFO96868.1 - 0.00067 19.1 4.0 0.00067 19.1 2.8 3.9 3 0 0 3 3 3 2 Pacifastin inhibitor (LCMII) Ank_2 PF12796.2 KFO96869.1 - 5.7e-35 119.5 6.7 1.6e-18 66.7 0.1 2.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFO96869.1 - 1.4e-29 100.3 1.7 7.8e-09 34.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFO96869.1 - 1.9e-27 95.1 1.2 1.2e-12 47.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO96869.1 - 3.1e-21 74.8 1.4 2.3e-10 40.3 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO96869.1 - 4.7e-19 66.5 0.8 2.8e-05 23.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat zf-RING_6 PF14835.1 KFO96869.1 - 9.2e-16 57.3 1.3 3.1e-15 55.6 0.9 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein BRCT PF00533.21 KFO96869.1 - 3.3e-12 46.3 0.5 1.6e-05 24.9 0.0 2.8 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFO96869.1 - 0.00067 19.4 0.1 0.008 16.0 0.0 2.5 2 0 0 2 2 2 1 twin BRCT domain ABC_tran PF00005.22 KFO96870.1 - 2.8e-53 179.8 2.4 7.1e-29 100.8 0.0 3.9 3 1 1 4 4 4 2 ABC transporter ABC2_membrane_3 PF12698.2 KFO96870.1 - 1.8e-46 158.7 47.6 1.5e-25 90.0 12.0 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFO96870.1 - 1.6e-25 90.6 3.8 4.3e-10 40.0 0.3 4.4 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFO96870.1 - 0.00049 19.3 0.7 21 4.2 0.1 4.3 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFO96870.1 - 0.00097 19.5 14.5 0.01 16.1 0.1 3.8 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KFO96870.1 - 0.0038 16.7 3.6 0.13 11.8 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KFO96870.1 - 0.006 15.7 0.8 1.1 8.4 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF4162 PF13732.1 KFO96870.1 - 0.01 16.3 0.0 0.045 14.2 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) SbcCD_C PF13558.1 KFO96870.1 - 0.072 13.0 0.0 17 5.3 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 KFO96870.1 - 1.2 8.4 6.8 1.4 8.3 0.1 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AICARFT_IMPCHas PF01808.13 KFO96871.1 - 2.6e-119 398.0 0.1 3.3e-119 397.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KFO96871.1 - 2.8e-24 84.8 0.0 6e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain fn3 PF00041.16 KFO96873.1 - 1.6e-262 848.5 78.3 7e-21 74.1 0.8 17.4 17 0 0 17 17 17 17 Fibronectin type III domain fn1 PF00039.13 KFO96873.1 - 1.7e-151 491.7 167.5 9.5e-15 54.1 6.3 12.6 12 0 0 12 12 12 12 Fibronectin type I domain fn2 PF00040.14 KFO96873.1 - 6e-35 118.9 20.1 1.3e-17 63.4 4.8 3.3 2 0 0 2 2 2 2 Fibronectin type II domain Interfer-bind PF09294.5 KFO96873.1 - 1.6e-17 63.4 0.2 1 9.4 0.0 12.8 12 0 0 12 12 12 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.4 KFO96873.1 - 1.4e-08 34.2 21.7 0.033 13.3 0.1 11.3 14 1 1 15 15 15 3 Uncharacterised conserved protein (DUF2369) DUF1410 PF07198.6 KFO96873.1 - 0.00044 20.4 3.3 28 5.1 0.0 7.4 8 0 0 8 8 8 0 Protein of unknown function (DUF1410) DUF2012 PF09430.5 KFO96873.1 - 0.0088 15.8 0.3 13 5.6 0.0 4.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2012) fn3_3 PF14686.1 KFO96873.1 - 0.033 14.3 1.7 14 5.9 0.1 4.3 5 0 0 5 5 5 0 Polysaccharide lyase family 4, domain II Glyco_hydro_66 PF13199.1 KFO96873.1 - 0.51 8.6 5.4 8.2 4.6 0.0 4.5 5 0 0 5 5 5 0 Glycosyl hydrolase family 66 SusE PF14292.1 KFO96873.1 - 4.6 7.0 16.6 58 3.5 0.0 7.9 9 0 0 9 9 9 0 SusE outer membrane protein COG5 PF10392.4 KFO96874.1 - 0.083 12.8 0.7 0.12 12.3 0.5 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 MetW PF07021.7 KFO96874.1 - 0.093 12.1 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW S_100 PF01023.14 KFO96875.1 - 1.7e-20 72.0 1.5 2.7e-20 71.3 1.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFO96875.1 - 0.00015 20.7 2.3 0.0002 20.4 0.2 2.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KFO96875.1 - 0.00018 21.5 1.0 0.00026 21.0 0.7 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFO96875.1 - 0.009 15.8 0.5 0.34 10.8 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KFO96875.1 - 0.016 14.8 1.5 0.027 14.0 1.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_4 PF12763.2 KFO96875.1 - 0.021 14.5 0.7 0.025 14.3 0.5 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Leuk-A4-hydro_C PF09127.6 KFO96875.1 - 0.031 13.8 0.1 0.042 13.4 0.1 1.1 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal DUF1451 PF07295.6 KFO96875.1 - 0.081 12.6 0.4 0.08 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) AMP-binding PF00501.23 KFO96876.1 - 1.5e-76 257.4 1.0 2.3e-50 171.2 0.1 2.4 2 0 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 KFO96876.1 - 3.7e-11 43.5 2.2 7.5e-11 42.6 1.5 1.5 1 0 0 1 1 1 1 DMAP1-binding Domain Macoilin PF09726.4 KFO96876.1 - 1.6 6.9 8.1 2.2 6.4 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein PACT_coil_coil PF10495.4 KFO96878.1 - 5.7e-34 115.8 0.1 7.6e-34 115.4 0.1 1.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein ENT PF03735.9 KFO96879.1 - 0.39 10.4 12.6 1 9.1 1.5 2.7 1 1 1 2 2 2 0 ENT domain SICA_alpha PF12887.2 KFO96879.1 - 2.4 7.8 10.6 1 9.1 1.0 2.2 2 0 0 2 2 2 0 SICA extracellular alpha domain Leucyl-specific PF14795.1 KFO96879.1 - 3.5 7.5 6.9 6.5 6.6 0.1 3.0 1 1 1 3 3 3 0 Leucine-tRNA synthetase-specific domain SAE2 PF08573.5 KFO96879.1 - 9.8 6.9 8.0 59 4.4 5.6 2.2 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4587 PF15248.1 KFO96880.1 - 6.8e-31 106.6 12.0 6.8e-31 106.6 8.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4587) FAD_binding_3 PF01494.14 KFO96881.1 - 2.6e-20 72.7 0.0 4e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFO96881.1 - 3e-06 27.1 0.3 8.9e-06 25.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFO96881.1 - 5.8e-06 25.4 0.0 0.00019 20.4 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 KFO96881.1 - 0.00014 20.7 0.1 0.094 11.5 0.0 2.4 2 1 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.22 KFO96881.1 - 0.00031 21.0 0.1 0.00061 20.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFO96881.1 - 0.0025 17.5 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFO96881.1 - 0.049 13.8 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KFO96881.1 - 0.075 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Integrin_beta PF00362.13 KFO96882.1 - 8.8e-174 578.3 0.0 1.3e-173 577.7 0.0 1.3 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 KFO96882.1 - 3.2e-19 68.0 0.9 6.5e-19 67.0 0.6 1.6 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 KFO96882.1 - 6e-16 58.6 11.3 6e-16 58.6 7.8 4.5 4 1 1 5 5 5 1 Integrin beta tail domain EGF_2 PF07974.8 KFO96882.1 - 0.00027 21.0 109.1 0.0024 17.9 8.1 7.7 7 1 1 8 8 8 4 EGF-like domain hEGF PF12661.2 KFO96882.1 - 0.0017 18.3 1.8 0.0017 18.3 1.3 6.1 5 2 1 6 6 6 1 Human growth factor-like EGF Syndecan PF01034.15 KFO96882.1 - 0.17 11.5 0.0 0.46 10.1 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain SLX9 PF15341.1 KFO96883.1 - 1.1e-14 54.9 7.4 1.2e-14 54.7 5.1 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 A_deamin PF02137.13 KFO96884.1 - 1e-124 416.3 0.0 1.3e-124 415.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 KFO96884.1 - 6e-29 100.4 0.2 4.5e-14 52.7 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFO96884.1 - 3.8e-05 23.8 0.1 0.16 12.3 0.0 2.9 2 0 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 Endostatin PF06482.6 KFO96885.1 - 2.5e-133 444.2 0.0 3.1e-133 443.9 0.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin Collagen PF01391.13 KFO96885.1 - 1.2e-62 207.3 358.8 3e-09 36.2 11.2 16.3 8 4 6 14 14 14 13 Collagen triple helix repeat (20 copies) Laminin_G_3 PF13385.1 KFO96885.1 - 1.8e-05 25.0 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Folate_carrier PF01770.13 KFO96886.1 - 2.8e-166 553.1 15.4 3.1e-166 552.9 10.7 1.0 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 KFO96886.1 - 2.4e-11 42.9 28.8 2.9e-11 42.7 20.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily KH_1 PF00013.24 KFO96887.1 - 4.5e-41 138.3 9.0 1.3e-17 63.1 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFO96887.1 - 3.5e-30 103.0 16.4 1e-13 50.5 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFO96887.1 - 3.1e-11 42.6 0.1 1.3e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 KFO96887.1 - 0.00089 19.0 1.4 0.94 9.3 0.1 2.3 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.1 KFO96887.1 - 0.0025 17.4 0.0 1.8 8.2 0.0 2.5 2 0 0 2 2 2 2 KH domain VWA PF00092.23 KFO96888.1 - 4.8e-86 287.0 4.6 3.5e-31 108.3 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.13 KFO96888.1 - 2.5e-52 174.2 204.7 4.7e-10 38.8 14.8 7.2 1 1 5 7 7 7 7 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 KFO96888.1 - 4.4e-36 124.5 0.2 4.6e-12 46.3 0.3 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_3 PF13768.1 KFO96888.1 - 1.3e-08 34.6 0.8 1e-05 25.2 0.0 3.9 4 1 0 4 4 4 1 von Willebrand factor type A domain DUF1194 PF06707.6 KFO96888.1 - 1.7e-05 23.9 1.1 0.046 12.6 0.6 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1194) VWA PF00092.23 KFO96889.1 - 5e-84 280.4 5.4 1e-34 119.7 0.1 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain Collagen PF01391.13 KFO96889.1 - 8.6e-52 172.5 203.9 1e-09 37.7 23.4 7.2 1 1 5 6 6 6 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 KFO96889.1 - 1.3e-30 106.7 0.4 8.2e-09 35.8 0.0 3.1 3 0 0 3 3 3 3 von Willebrand factor type A domain FTCD PF02971.9 KFO96890.1 - 1.3e-79 264.8 0.1 2.3e-79 264.0 0.1 1.4 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_N PF07837.7 KFO96890.1 - 3.7e-74 248.0 0.0 5.8e-74 247.4 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.7 KFO96890.1 - 5e-62 208.6 0.3 8.1e-62 207.9 0.2 1.4 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Keratin PF02422.11 KFO96891.1 - 4.9e-32 109.7 13.9 5.1e-32 109.7 9.7 1.0 1 0 0 1 1 1 1 Keratin SAC3_GANP PF03399.11 KFO96892.1 - 2.5e-55 187.2 2.9 4.8e-55 186.2 2.0 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KFO96892.1 - 8.2e-05 22.3 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RRM_6 PF14259.1 KFO96892.1 - 0.0031 17.4 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO96892.1 - 0.16 11.6 0.0 0.43 10.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAC3 PF12209.3 KFO96892.1 - 7.7 6.7 9.3 41 4.4 2.8 4.0 2 1 1 3 3 3 0 Leucine permease transcriptional regulator helical domain UPF0054 PF02130.12 KFO96893.1 - 9.5e-27 93.0 0.0 1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 O-FucT PF10250.4 KFO96894.1 - 1.1e-81 274.7 0.0 1.4e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1699 PF08004.6 KFO96894.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) PAS_3 PF08447.6 KFO96895.1 - 1.3e-16 60.4 0.3 1e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KFO96895.1 - 1.5e-12 47.4 0.0 1.8e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFO96895.1 - 6.8e-11 41.9 0.0 2e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KFO96895.1 - 2.2e-06 27.9 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFO96895.1 - 0.07 13.1 0.1 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 PAS fold SWIM PF04434.12 KFO96898.1 - 0.04 13.3 3.4 0.11 11.9 2.4 1.8 1 0 0 1 1 1 0 SWIM zinc finger RVT_1 PF00078.22 KFO96899.1 - 7e-14 51.6 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KFO96900.1 - 1.7e-23 83.0 0.2 2.6e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.19 KFO96900.1 - 2.2e-10 40.9 0.0 4.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 RNase H Integrase_Zn PF02022.14 KFO96900.1 - 5.8e-10 38.4 0.2 1.1e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Integrase Zinc binding domain DDE_Tnp_IS240 PF13610.1 KFO96900.1 - 0.00026 20.9 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 DDE domain RVT_1 PF00078.22 KFO96902.1 - 2.1e-14 53.3 0.0 3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KFO96902.1 - 0.097 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_4 PF13853.1 KFO96903.1 - 1.6e-45 154.4 5.9 1.6e-45 154.4 4.1 2.5 3 1 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFO96903.1 - 1.2e-29 103.2 8.3 1.6e-29 102.8 5.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Reticulon PF02453.12 KFO96903.1 - 0.041 13.5 0.2 0.041 13.5 0.2 2.7 3 1 1 4 4 4 0 Reticulon 7TM_GPCR_Srsx PF10320.4 KFO96903.1 - 0.2 10.8 14.9 0.32 10.1 10.3 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Cep57_CLD_2 PF14197.1 KFO96904.1 - 0.062 13.2 7.3 2.1 8.3 1.6 2.9 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 Pfg27 PF09216.5 KFO96904.1 - 0.065 12.8 1.2 0.1 12.1 0.8 1.4 1 1 0 1 1 1 0 Pfg27 CorA PF01544.13 KFO96904.1 - 0.068 12.2 2.6 0.091 11.7 1.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF904 PF06005.7 KFO96904.1 - 0.072 13.3 7.1 0.28 11.5 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) PRD PF00874.15 KFO96904.1 - 0.15 12.1 2.9 8.9 6.5 0.1 2.2 2 0 0 2 2 2 0 PRD domain DivIVA PF05103.8 KFO96904.1 - 0.19 11.8 9.4 2.1 8.4 6.4 2.0 1 1 0 1 1 1 0 DivIVA protein Rootletin PF15035.1 KFO96904.1 - 0.25 11.2 7.7 1.1 9.1 1.9 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.8 KFO96904.1 - 0.35 11.2 6.3 0.39 11.0 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF342 PF03961.8 KFO96904.1 - 0.39 9.0 4.4 0.48 8.7 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Kinesin-relat_1 PF12711.2 KFO96904.1 - 0.46 10.9 7.7 3 8.2 0.8 2.2 1 1 1 2 2 2 0 Kinesin motor Seryl_tRNA_N PF02403.17 KFO96904.1 - 0.47 10.4 5.2 1.8 8.6 3.6 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF837 PF05769.6 KFO96904.1 - 0.49 9.9 9.5 1.2 8.6 2.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF837) IncA PF04156.9 KFO96904.1 - 0.5 9.9 5.0 0.85 9.1 3.5 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KFO96904.1 - 0.74 8.8 7.5 1.1 8.2 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 KFO96904.1 - 1.1 9.0 7.5 3.5 7.4 0.4 2.2 2 0 0 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.16 KFO96904.1 - 1.4 8.9 8.8 0.59 10.1 0.9 2.7 2 1 1 3 3 3 0 bZIP transcription factor HALZ PF02183.13 KFO96904.1 - 1.9 8.2 7.9 3.7 7.3 0.9 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 KFO96904.1 - 2 8.2 7.0 1.8 8.3 0.4 2.8 2 1 1 3 3 3 0 Sperm tail C-terminal domain Val_tRNA-synt_C PF10458.4 KFO96904.1 - 2.2 8.4 6.4 1.4 9.0 1.0 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm zf-H2C2_2 PF13465.1 KFO96905.1 - 9.8e-20 69.8 31.8 2e-08 34.1 1.9 7.5 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFO96905.1 - 1.1e-15 56.8 43.8 0.00014 22.0 0.9 6.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO96905.1 - 1.4e-09 37.5 42.0 0.0014 18.8 0.6 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFO96905.1 - 0.0031 17.5 3.0 0.0031 17.5 2.1 5.3 4 2 3 7 7 7 1 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 KFO96905.1 - 0.017 14.7 3.1 0.14 11.7 0.0 3.0 2 1 1 3 3 3 0 GAGA factor zf-C2H2_jaz PF12171.3 KFO96905.1 - 0.025 14.7 28.1 0.66 10.1 0.3 7.0 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFO96905.1 - 0.052 13.7 1.0 0.052 13.7 0.7 6.1 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-met PF12874.2 KFO96905.1 - 0.13 12.5 0.2 0.13 12.5 0.1 6.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KFO96905.1 - 0.47 10.8 15.2 0.24 11.7 2.6 3.7 3 0 0 3 3 3 0 TRAF-type zinc finger GATA PF00320.22 KFO96905.1 - 0.5 9.7 9.7 5.9 6.3 0.3 4.1 4 0 0 4 4 4 0 GATA zinc finger zf-C2H2_6 PF13912.1 KFO96905.1 - 8.3 6.4 37.5 0.48 10.3 2.6 7.0 7 1 0 7 7 7 0 C2H2-type zinc finger Pkinase_Tyr PF07714.12 KFO96906.1 - 1.6e-91 305.9 0.0 2.9e-91 305.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.19 KFO96906.1 - 9.6e-58 193.0 4.6 5e-30 103.7 0.2 2.5 2 0 0 2 2 2 2 Receptor L domain GF_recep_IV PF14843.1 KFO96906.1 - 1.3e-52 176.9 80.9 6.6e-47 158.4 19.4 4.1 2 1 1 3 3 3 3 Growth factor receptor domain IV Pkinase PF00069.20 KFO96906.1 - 1.1e-41 142.7 0.0 1.7e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 KFO96906.1 - 1.6e-35 121.9 86.7 2.3e-28 98.7 29.0 4.4 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.18 KFO96906.1 - 0.0047 16.6 0.1 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFO96906.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CPSase_L_D2 PF02786.12 KFO96907.1 - 1.2e-112 374.3 0.6 6.2e-81 270.7 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KFO96907.1 - 3.4e-43 146.2 0.0 7.9e-43 145.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 KFO96907.1 - 2.5e-38 130.6 0.1 5e-38 129.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KFO96907.1 - 3.9e-36 123.4 0.0 5e-19 68.4 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain GATase PF00117.23 KFO96907.1 - 1.9e-34 118.7 0.0 3.6e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ATP-grasp_4 PF13535.1 KFO96907.1 - 8.9e-30 103.7 0.5 8.7e-17 61.4 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KFO96907.1 - 1.1e-20 73.3 0.0 1.8e-19 69.4 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.17 KFO96907.1 - 1.5e-18 66.7 0.2 2.9e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFO96907.1 - 6.1e-15 54.7 0.0 5.9e-07 28.5 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFO96907.1 - 9e-13 48.0 0.6 1.1e-05 24.8 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KFO96907.1 - 4e-05 23.5 0.1 0.056 13.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain LANC_like PF05147.8 KFO96908.1 - 1.2e-105 352.9 1.2 1.5e-105 352.6 0.8 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_hydro_88 PF07470.8 KFO96908.1 - 0.0028 16.7 0.1 0.88 8.5 0.0 2.4 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KFO96908.1 - 0.0085 14.4 1.0 0.69 8.1 0.3 2.4 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) C5-epim_C PF06662.8 KFO96908.1 - 0.017 14.4 5.8 1.5 8.0 0.0 3.7 3 1 1 4 4 4 0 D-glucuronyl C5-epimerase C-terminus EF-hand_7 PF13499.1 KFO96909.1 - 9.3e-12 44.9 0.2 9.6e-07 28.8 0.0 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFO96909.1 - 1.6e-11 43.0 0.8 0.00087 18.9 0.1 4.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KFO96909.1 - 2.5e-11 42.0 4.7 0.019 14.2 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFO96909.1 - 2.9e-05 23.5 3.2 0.098 12.2 0.1 3.9 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 KFO96909.1 - 0.0054 16.6 0.0 3.2 7.7 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 KFO96909.1 - 0.025 14.1 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF2267 PF10025.4 KFO96909.1 - 0.13 12.3 0.1 0.91 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Acyl-CoA_dh_1 PF00441.19 KFO96910.1 - 1.2e-42 145.6 0.2 1.7e-42 145.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFO96910.1 - 3e-29 101.8 0.0 6.9e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFO96910.1 - 1.5e-19 69.2 1.3 1e-18 66.5 0.1 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFO96910.1 - 2.9e-08 34.0 0.0 4.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KFO96910.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal PEHE PF15275.1 KFO96911.1 - 2e-23 83.1 7.9 2e-23 83.1 5.5 3.4 3 0 0 3 3 3 1 PEHE domain Ribul_P_3_epim PF00834.14 KFO96912.1 - 1.2e-45 155.0 0.1 1.4e-45 154.8 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 KFO96912.1 - 0.0015 18.0 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.12 KFO96912.1 - 0.002 17.2 0.0 0.0032 16.6 0.0 1.3 1 1 0 1 1 1 1 Thiamine monophosphate synthase/TENI OMPdecase PF00215.19 KFO96912.1 - 0.0031 16.9 0.0 0.0058 16.0 0.0 1.3 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.16 KFO96912.1 - 0.057 12.6 0.0 0.41 9.8 0.0 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein Glyco_hydro_31 PF01055.21 KFO96912.1 - 0.1 11.4 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 PG_binding_3 PF09374.5 KFO96912.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Tubulin-binding PF00418.14 KFO96915.1 - 1.1e-64 213.6 23.4 5.3e-17 61.2 1.8 5.4 5 0 0 5 5 5 4 Tau and MAP protein, tubulin-binding repeat RII_binding_1 PF10522.4 KFO96915.1 - 0.042 13.9 3.5 0.13 12.4 2.4 1.9 1 0 0 1 1 1 0 RII binding domain DUF1880 PF08976.6 KFO96915.1 - 0.72 9.9 10.2 0.042 13.9 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) NTR PF01759.16 KFO96916.1 - 8.2e-22 76.8 5.1 3.9e-21 74.6 0.3 2.0 1 1 1 2 2 2 2 UNC-6/NTR/C345C module Pneumo_matrix PF03393.11 KFO96916.1 - 0.06 12.2 1.1 0.079 11.8 0.8 1.1 1 0 0 1 1 1 0 Pneumovirus matrix protein Nckap1 PF09735.4 KFO96917.1 - 0 1774.6 27.1 0 1774.4 18.8 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DSPc PF00782.15 KFO96918.1 - 1.6e-32 111.9 0.0 1.7e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO96918.1 - 0.00072 18.9 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Nup35_RRM PF05172.8 KFO96919.1 - 1.2e-26 92.4 0.1 1.9e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KFO96919.1 - 1.4e-13 50.4 0.0 2.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KFO96919.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAP1_N PF04849.8 KFO96920.1 - 3.6e-110 367.7 35.7 5.2e-110 367.1 24.8 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.3 KFO96920.1 - 9.8e-56 188.4 21.2 1.7e-35 122.6 2.7 3.0 3 0 0 3 3 3 2 Kinesin associated protein DUF4279 PF14106.1 KFO96920.1 - 0.37 10.6 3.8 1.8 8.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) AATF-Che1 PF13339.1 KFO96920.1 - 2.8 8.0 18.0 4.2 7.5 4.3 2.9 1 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF4326 PF14216.1 KFO96920.1 - 2.9 8.5 7.1 1.4e+02 3.1 4.9 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4326) DUF948 PF06103.6 KFO96920.1 - 3.5 7.5 5.7 26 4.7 0.5 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 KFO96920.1 - 5.5 7.3 25.6 5.7 7.3 2.8 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) PLRV_ORF5 PF01690.12 KFO96920.1 - 9.5 5.2 6.7 15 4.5 4.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pkinase PF00069.20 KFO96921.1 - 8e-36 123.5 0.0 1.3e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96921.1 - 3.9e-29 101.5 0.0 2.9e-25 88.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFO96921.1 - 0.0072 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like EBP PF05241.7 KFO96921.1 - 0.033 13.1 0.2 0.053 12.5 0.2 1.2 1 0 0 1 1 1 0 Emopamil binding protein TMEM237 PF15383.1 KFO96922.1 - 1.3e-91 306.2 0.1 1.9e-91 305.7 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 237 SOBP PF15279.1 KFO96922.1 - 0.43 10.8 7.8 0.6 10.4 5.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RCC1 PF00415.13 KFO96923.1 - 9.1e-41 137.8 22.8 3e-12 46.5 0.1 7.6 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat MORN PF02493.15 KFO96923.1 - 1.2e-26 90.7 31.5 2.5e-05 23.7 1.9 9.7 9 1 0 9 9 9 7 MORN repeat RCC1_2 PF13540.1 KFO96923.1 - 7.7e-26 89.1 33.5 7.6e-08 31.7 1.6 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat VPS9 PF02204.13 KFO96923.1 - 2.8e-23 81.8 0.1 1.8e-22 79.3 0.2 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RhoGEF PF00621.15 KFO96923.1 - 1.9e-06 27.8 0.8 4.2e-06 26.7 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFO96923.1 - 0.018 15.2 0.1 0.049 13.8 0.0 1.7 2 0 0 2 2 2 0 PH domain YoaP PF14268.1 KFO96923.1 - 0.14 11.3 0.1 0.38 10.0 0.0 1.7 1 0 0 1 1 1 0 YoaP-like SERTA PF06031.8 KFO96924.1 - 6.3e-17 60.5 1.3 1e-16 59.9 0.9 1.3 1 0 0 1 1 1 1 SERTA motif Clathrin_bdg PF15045.1 KFO96925.1 - 5.5e-33 112.3 0.0 1.5e-32 110.9 0.0 1.8 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Gal-bind_lectin PF00337.17 KFO96926.1 - 1.1e-29 102.4 0.0 1.2e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin DUF2189 PF09955.4 KFO96927.1 - 0.23 11.3 4.4 0.48 10.3 3.0 1.6 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Pellino PF04710.9 KFO96928.1 - 9.1e-228 755.8 0.3 1e-227 755.6 0.2 1.0 1 0 0 1 1 1 1 Pellino zf-C3HC4_3 PF13920.1 KFO96928.1 - 0.00063 19.3 6.5 0.43 10.2 0.2 3.1 2 2 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO96928.1 - 0.0009 19.2 6.8 0.024 14.6 0.0 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFO96928.1 - 0.0058 16.3 0.8 5.8 6.7 0.0 3.1 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.1 KFO96928.1 - 0.24 11.2 13.0 1 9.2 1.5 3.3 3 1 0 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.1 KFO96928.1 - 2.1 7.9 10.9 5 6.7 0.1 3.7 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KFO96928.1 - 3.2 7.9 7.1 0.69 10.0 0.2 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_5 PF14634.1 KFO96928.1 - 4.1 7.1 10.3 0.49 10.1 0.1 3.5 2 2 0 2 2 2 0 zinc-RING finger domain Vps54 PF07928.7 KFO96929.1 - 8.8e-60 200.7 3.7 8.9e-60 200.7 0.6 2.5 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KFO96929.1 - 3.5e-09 35.9 7.6 3.5e-09 35.9 5.3 2.8 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) UDPGP PF01704.13 KFO96930.1 - 1.9e-192 639.4 0.6 2.5e-192 639.0 0.4 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 KFO96930.1 - 0.0084 14.7 0.2 1.2 7.5 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4301) Ldh_1_C PF02866.13 KFO96932.1 - 5.8e-50 169.4 0.1 1.6e-49 167.9 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KFO96932.1 - 1.4e-38 131.9 0.1 2.8e-38 130.9 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF3312 PF11768.3 KFO96933.1 - 4.2e-247 820.7 0.3 4.8e-247 820.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Homeobox PF00046.24 KFO96935.1 - 2.7e-23 81.3 1.3 3.1e-23 81.1 0.9 1.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO96935.1 - 0.048 13.3 0.4 0.24 11.1 0.1 1.9 1 1 1 2 2 2 0 Homeobox KN domain Transmemb_17 PF09799.4 KFO96936.1 - 1.6e-32 112.0 12.5 2.6e-32 111.4 8.6 1.3 1 0 0 1 1 1 1 Predicted membrane protein EGF_CA PF07645.10 KFO96937.1 - 2.2e-08 33.9 7.0 2.2e-08 33.9 4.9 2.1 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 KFO96937.1 - 0.0015 18.4 5.9 0.0025 17.7 4.1 1.4 1 0 0 1 1 1 1 EGF domain EGF_MSP1_1 PF12946.2 KFO96937.1 - 0.018 14.7 2.8 0.018 14.7 1.9 1.7 2 0 0 2 2 2 0 MSP1 EGF domain 1 EGF PF00008.22 KFO96937.1 - 0.037 13.9 5.6 0.045 13.7 2.8 1.9 2 0 0 2 2 2 0 EGF-like domain Galactosyl_T PF01762.16 KFO96938.1 - 4.8e-42 143.7 0.0 7.9e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 KFO96938.1 - 0.0023 17.1 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KFO96938.1 - 0.0072 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 HCaRG PF07258.9 KFO96939.1 - 4.6e-45 153.3 0.4 5.2e-45 153.1 0.3 1.0 1 0 0 1 1 1 1 HCaRG protein PRP38 PF03371.10 KFO96939.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PRP38 family CDP-OH_P_transf PF01066.16 KFO96940.1 - 1.4e-14 54.2 6.0 2.3e-14 53.5 4.2 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MCM PF00493.18 KFO96941.1 - 3.1e-121 404.2 0.0 3.9e-121 403.8 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KFO96941.1 - 2.7e-08 33.2 0.0 5.5e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFO96941.1 - 1.5e-07 31.1 0.0 3.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFO96941.1 - 0.00037 20.1 0.0 0.001 18.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.1 KFO96941.1 - 0.0026 18.2 2.5 0.0096 16.4 0.1 2.7 3 0 0 3 3 3 1 MCM N-terminal domain FtsK_SpoIIIE PF01580.13 KFO96941.1 - 0.0033 16.9 0.0 0.01 15.3 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.24 KFO96941.1 - 0.0053 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFO96941.1 - 0.008 16.3 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFO96941.1 - 0.028 14.4 3.0 0.83 9.6 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain NTPase_1 PF03266.10 KFO96941.1 - 0.028 14.1 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 NTPase Gcd10p PF04189.8 KFO96942.1 - 1e-75 254.6 0.2 1e-75 254.6 0.2 2.3 1 1 1 2 2 2 1 Gcd10p family INTS5_C PF14838.1 KFO96942.1 - 0.051 11.8 0.1 0.08 11.2 0.1 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Granin PF01271.12 KFO96943.1 - 2e-18 66.4 120.3 3.6e-18 65.6 83.4 1.4 1 1 0 1 1 1 1 Granin (chromogranin or secretogranin) UPF0020 PF01170.13 KFO96944.1 - 1e-30 106.6 0.0 3.5e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KFO96944.1 - 2.4e-14 53.3 0.0 3.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO96944.1 - 4.2e-14 52.3 0.0 6.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO96944.1 - 3.4e-11 43.4 0.0 1.2e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFO96944.1 - 9.9e-09 34.7 0.0 1.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain THUMP PF02926.12 KFO96944.1 - 3e-08 33.6 0.0 6.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Methyltransf_25 PF13649.1 KFO96944.1 - 9e-08 32.4 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFO96944.1 - 2.3e-07 30.1 0.0 3.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFO96944.1 - 2.3e-05 24.9 0.0 4.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KFO96944.1 - 0.0087 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase CMAS PF02353.15 KFO96944.1 - 0.0093 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KFO96944.1 - 0.022 15.2 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 KFO96944.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MARVEL PF01284.18 KFO96945.1 - 9.5e-12 44.9 14.8 1.5e-11 44.2 10.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain Caa3_CtaG PF09678.5 KFO96945.1 - 0.33 9.8 9.1 1.2 8.0 6.3 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Caps_synth_CapC PF14102.1 KFO96945.1 - 1.1 9.3 8.7 1.9 8.6 1.1 2.1 1 1 1 2 2 2 0 Capsule biosynthesis CapC Claudin_3 PF06653.6 KFO96945.1 - 4.8 6.8 10.7 13 5.4 4.4 2.3 1 1 1 2 2 2 0 Tight junction protein, Claudin-like DUF1218 PF06749.7 KFO96945.1 - 7.8 7.0 12.2 0.97 9.9 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Ribosomal_S5_C PF03719.10 KFO96946.1 - 8e-21 73.1 0.1 1.6e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KFO96946.1 - 5.3e-11 42.0 1.2 5.3e-11 42.0 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Yae1_N PF09811.4 KFO96947.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Calx-beta PF03160.9 KFO96948.1 - 3.1e-62 206.7 6.0 1.5e-35 121.1 0.6 2.6 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.19 KFO96948.1 - 2e-61 205.6 23.3 1e-34 119.0 4.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DnaG_DnaB_bind PF08278.6 KFO96948.1 - 0.17 12.0 2.5 0.34 11.1 1.7 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding ArsR PF09824.4 KFO96950.1 - 0.03 13.6 0.5 0.07 12.4 0.2 1.7 1 1 0 1 1 1 0 ArsR transcriptional regulator DUF2922 PF11148.3 KFO96950.1 - 0.061 12.9 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Ldh_1_N PF00056.18 KFO96950.1 - 0.083 12.7 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF1313 PF07011.6 KFO96950.1 - 0.21 11.2 6.8 3.3 7.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1313) Med15 PF09606.5 KFO96950.1 - 3.8 5.5 20.6 4.4 5.3 14.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Asp-B-Hydro_N PF05279.6 KFO96950.1 - 7.5 6.3 15.1 9.8 5.9 10.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Cauli_AT PF03233.8 KFO96950.1 - 8.5 6.0 8.8 3.8 7.1 1.2 2.1 1 1 1 2 2 2 0 Aphid transmission protein DEAD PF00270.24 KFO96951.1 - 3.8e-41 140.3 0.5 7.2e-41 139.4 0.2 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO96951.1 - 5.6e-28 96.6 0.0 1.3e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFO96951.1 - 0.00042 20.0 0.1 0.00092 18.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFO96951.1 - 0.0011 18.6 0.1 0.0026 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFO96951.1 - 0.0011 18.8 0.1 0.0024 17.7 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KFO96951.1 - 0.024 13.0 0.0 0.44 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 KFO96951.1 - 0.032 14.3 0.2 0.13 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KFO96951.1 - 0.094 12.4 0.2 0.34 10.6 0.0 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain GBP PF02263.14 KFO96952.1 - 5.5e-101 336.9 0.1 7.3e-101 336.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 KFO96952.1 - 1.6e-06 27.5 0.1 3.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain RRM_5 PF13893.1 KFO96953.1 - 2.5e-36 123.3 9.1 2.3e-16 59.3 0.1 4.4 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96953.1 - 4e-23 81.1 1.5 4.9e-12 45.6 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO96953.1 - 7.1e-17 60.8 1.4 4.2e-07 29.5 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO96953.1 - 0.0035 17.1 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 KFO96953.1 - 0.011 15.4 0.0 0.53 10.0 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 DUF1272 PF06906.6 KFO96953.1 - 0.15 11.9 2.7 0.46 10.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Aldose_epim PF01263.15 KFO96955.1 - 7.7e-99 330.5 0.0 8.6e-99 330.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RRM_1 PF00076.17 KFO96956.1 - 2.3e-16 59.1 0.0 3.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96956.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96956.1 - 2.5e-10 40.0 0.0 3.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 KFO96956.1 - 0.0004 20.0 2.3 0.0011 18.6 1.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFO96956.1 - 0.00058 19.6 6.1 0.0011 18.7 4.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Gemin6 PF06372.7 KFO96957.1 - 3.9e-65 218.2 0.7 4.3e-65 218.0 0.5 1.0 1 0 0 1 1 1 1 Gemin6 protein RRM_1 PF00076.17 KFO96958.1 - 7.8e-16 57.4 0.0 1.1e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO96958.1 - 8.9e-10 38.4 0.0 1.3e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO96958.1 - 2.7e-09 36.7 0.0 4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 KFO96958.1 - 0.00038 20.1 2.4 0.0011 18.6 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFO96958.1 - 0.00054 19.7 6.1 0.0011 18.8 4.2 1.4 1 0 0 1 1 1 1 Zinc knuckle OB_NTP_bind PF07717.11 KFO96959.1 - 1.7e-11 43.9 0.0 2.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RhoGEF PF00621.15 KFO96960.1 - 2.5e-17 63.3 3.9 4.5e-17 62.4 2.7 1.4 1 1 0 1 1 1 1 RhoGEF domain TraU PF06834.6 KFO96961.1 - 0.077 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 TraU protein RasGEF PF00617.14 KFO96962.1 - 3.2e-51 173.7 0.7 7.1e-51 172.6 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFO96962.1 - 3.2e-31 107.5 0.0 1.2e-30 105.6 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGEF PF00621.15 KFO96962.1 - 1.4e-17 64.1 0.2 1.4e-17 64.1 0.1 2.4 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFO96962.1 - 4e-13 49.4 0.2 2.2e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 PH domain Histone PF00125.19 KFO96962.1 - 2.7e-12 46.6 0.0 8.3e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PH_10 PF15411.1 KFO96962.1 - 0.00023 21.3 0.0 0.00076 19.6 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Herpes_UL92 PF03048.9 KFO96962.1 - 0.0077 15.8 0.0 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 UL92 family Pkinase PF00069.20 KFO96963.1 - 1.2e-64 218.0 0.0 1.7e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.17 KFO96963.1 - 1.1e-61 208.6 0.4 1.9e-61 207.9 0.3 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 KFO96963.1 - 3.8e-40 137.5 0.0 5.7e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO96963.1 - 0.012 14.6 0.0 0.029 13.3 0.0 1.6 1 0 0 1 1 1 0 Kinase-like IBR PF01485.16 KFO96964.1 - 2.4e-11 43.3 34.9 6.3e-08 32.3 6.0 3.4 3 1 0 3 3 3 2 IBR domain Cullin_Nedd8 PF10557.4 KFO96965.1 - 0.036 13.8 0.1 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 Cullin protein neddylation domain Cul7 PF11515.3 KFO96966.1 - 6.8e-18 64.3 0.3 1.2e-17 63.5 0.2 1.4 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 Chromo PF00385.19 KFO96966.1 - 0.053 13.2 0.4 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain SRF-TF PF00319.13 KFO96967.1 - 2.2e-08 33.1 0.1 3.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) I-set PF07679.11 KFO96968.1 - 9.7e-86 281.7 0.0 8.1e-15 54.4 0.0 7.4 7 0 0 7 7 7 7 Immunoglobulin I-set domain Pkinase_Tyr PF07714.12 KFO96968.1 - 1.1e-82 277.0 0.0 1.5e-82 276.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_2 PF13895.1 KFO96968.1 - 1.2e-69 230.4 9.6 1.7e-12 47.2 0.1 7.3 7 0 0 7 7 7 7 Immunoglobulin domain Ig_3 PF13927.1 KFO96968.1 - 2.6e-48 162.3 10.3 1e-09 38.7 0.3 7.5 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.20 KFO96968.1 - 1.1e-46 156.8 11.6 3.5e-09 36.6 0.4 7.9 7 2 0 7 7 7 6 Immunoglobulin domain Pkinase PF00069.20 KFO96968.1 - 2.1e-42 145.0 0.0 3.2e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain V-set PF07686.12 KFO96968.1 - 4.2e-30 103.9 6.6 0.00034 20.4 0.2 8.4 7 3 0 7 7 7 6 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO96968.1 - 5.4e-15 55.0 11.6 0.0033 17.2 0.1 6.9 7 0 0 7 7 7 5 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFO96968.1 - 1.5e-09 36.6 0.7 0.19 9.9 0.0 5.8 3 2 2 6 6 6 3 Alphaherpesvirus glycoprotein E C1-set PF07654.10 KFO96968.1 - 3.5e-07 30.1 4.6 0.37 10.8 0.0 6.0 5 1 0 5 5 5 2 Immunoglobulin C1-set domain V-set_CD47 PF08204.6 KFO96968.1 - 1.9e-05 24.4 0.4 0.44 10.3 0.0 4.0 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain C2-set PF05790.10 KFO96968.1 - 3.1e-05 23.8 1.4 8.3 6.4 0.0 6.1 7 0 0 7 7 7 1 Immunoglobulin C2-set domain Sp38 PF07354.7 KFO96968.1 - 0.0002 20.1 1.0 0.3 9.6 0.0 4.3 4 1 0 5 5 5 1 Zona-pellucida-binding protein (Sp38) CD34_antigen PF06365.7 KFO96968.1 - 0.0026 17.4 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family SKG6 PF08693.5 KFO96968.1 - 0.042 13.1 0.3 0.095 12.0 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rab5-bind PF09311.6 KFO96969.1 - 2.6e-66 222.9 23.2 1.7e-64 217.0 7.4 3.2 4 0 0 4 4 3 2 Rabaptin-like protein TPR_12 PF13424.1 KFO96969.1 - 3.6e-63 209.4 19.0 1.9e-22 78.9 0.6 5.7 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 KFO96969.1 - 9.5e-62 203.3 11.8 4.6e-16 58.1 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFO96969.1 - 7.2e-27 91.8 29.1 1.1e-07 31.1 0.3 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFO96969.1 - 2.8e-24 82.9 17.2 6.3e-06 25.6 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFO96969.1 - 5.3e-24 83.6 18.4 3.8e-10 39.2 1.6 4.8 4 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 KFO96969.1 - 3.4e-20 72.1 3.8 7e-06 26.5 0.0 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFO96969.1 - 1.6e-18 65.0 25.3 0.00065 19.4 0.3 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFO96969.1 - 4.5e-14 52.5 9.3 0.00016 21.9 0.0 4.8 4 1 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFO96969.1 - 1.1e-12 47.3 6.1 0.49 11.1 0.0 6.8 3 1 4 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFO96969.1 - 1.8e-12 46.3 6.3 0.11 12.7 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFO96969.1 - 4.8e-12 44.7 20.1 0.069 12.9 0.3 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KFO96969.1 - 6.1e-11 42.3 9.2 2.7e-05 24.2 0.1 3.4 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFO96969.1 - 7.6e-07 28.9 1.9 1.6 9.3 0.1 6.6 8 0 0 8 8 6 1 Tetratricopeptide repeat PPR PF01535.15 KFO96969.1 - 6.3e-05 22.6 1.6 0.084 12.8 0.0 4.5 6 0 0 6 6 4 1 PPR repeat SHNi-TPR PF10516.4 KFO96969.1 - 0.0014 17.7 1.8 3.4 6.9 0.0 4.3 4 0 0 4 4 4 1 SHNi-TPR DUF627 PF04781.7 KFO96969.1 - 0.019 14.5 1.1 7.9 6.1 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF627) DUF3972 PF13118.1 KFO96969.1 - 0.042 13.9 11.7 1.3 9.1 2.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) PPR_3 PF13812.1 KFO96969.1 - 0.065 13.5 0.5 19 5.8 0.0 4.2 5 0 0 5 5 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFO96969.1 - 0.15 12.0 0.3 3.1 7.8 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family Exonuc_VII_L PF02601.10 KFO96969.1 - 0.32 10.1 7.3 0.45 9.6 5.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_6 PF13174.1 KFO96969.1 - 0.53 10.8 15.1 1.3 9.6 0.1 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.3 KFO96969.1 - 1.7 8.5 19.8 0.022 14.5 6.4 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 KFO96969.1 - 1.8 6.8 7.7 3 6.1 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) COG2 PF06148.6 KFO96969.1 - 2.4 8.0 10.3 0.16 11.8 3.3 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L2_C PF03947.13 KFO96970.1 - 1e-30 106.1 0.0 1.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFO96970.1 - 2e-13 50.0 0.3 4.5e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cul7 PF11515.3 KFO96971.1 - 1.5e-27 95.2 0.1 3.3e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 Mouse development and cellular proliferation protein Cullin-7 Cullin PF00888.17 KFO96972.1 - 1.8e-31 109.4 0.0 2.3e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family APC10 PF03256.11 KFO96972.1 - 0.0071 15.9 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Cullin_Nedd8 PF10557.4 KFO96973.1 - 0.014 15.2 0.1 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Cullin protein neddylation domain Pacs-1 PF10254.4 KFO96974.1 - 1.2e-176 587.4 0.8 1.7e-176 586.9 0.5 1.2 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein CECR6_TMEM121 PF14997.1 KFO96975.1 - 6.3e-62 208.6 13.9 1.1e-61 207.8 9.7 1.4 1 0 0 1 1 1 1 CECR6/TMEM121 family EIID-AGA PF03613.9 KFO96975.1 - 5.9e-05 22.1 1.2 7e-05 21.8 0.4 1.4 1 1 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component DUF947 PF06102.7 KFO96976.1 - 1.7e-43 148.3 31.3 2e-43 148.1 21.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF947) DUF3453 PF11935.3 KFO96976.1 - 0.036 13.4 6.4 0.06 12.7 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Muted PF14942.1 KFO96976.1 - 0.25 11.2 15.6 0.39 10.5 10.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Imm23 PF15593.1 KFO96976.1 - 0.72 10.0 3.2 0.83 9.8 2.2 1.1 1 0 0 1 1 1 0 Immunity protein 23 B56 PF01603.15 KFO96977.1 - 1.1e-176 587.4 6.2 1.4e-176 587.1 4.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Abhydrolase_5 PF12695.2 KFO96978.1 - 5.2e-19 68.4 0.0 1e-18 67.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFO96978.1 - 2.4e-17 63.5 0.1 7.4e-17 61.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO96978.1 - 3e-09 36.7 0.3 4e-06 26.5 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFO96978.1 - 8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFO96978.1 - 0.00022 21.0 0.3 0.00042 20.0 0.2 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KFO96978.1 - 0.002 17.3 0.0 0.0074 15.5 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFO96978.1 - 0.006 16.0 0.0 0.03 13.7 0.0 2.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KFO96978.1 - 0.0073 16.5 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain LIP PF03583.9 KFO96978.1 - 0.018 14.2 0.1 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Peptidase_S15 PF02129.13 KFO96978.1 - 0.029 13.7 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2424 PF10340.4 KFO96978.1 - 0.085 11.4 0.0 0.19 10.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Phosphorylase PF00343.15 KFO96979.1 - 0 1212.1 0.0 0 1211.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase GDA1_CD39 PF01150.12 KFO96980.1 - 1.6e-75 254.2 0.0 2.8e-74 250.1 0.0 2.3 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KFO96980.1 - 0.078 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF1507 PF07408.6 KFO96980.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) Homeobox PF00046.24 KFO96981.1 - 7.2e-24 83.1 2.6 1.4e-23 82.2 1.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO96981.1 - 0.0051 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Methyltransf_31 PF13847.1 KFO96982.1 - 1.6e-08 34.2 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO96982.1 - 1e-07 32.5 0.0 1.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO96982.1 - 3.3e-06 27.4 0.0 5.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO96982.1 - 1.8e-05 25.1 0.0 3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO96982.1 - 7.9e-05 22.4 0.0 9.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO96982.1 - 0.00015 22.0 0.0 0.00046 20.5 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain DUF3456 PF11938.3 KFO96983.1 - 7.4e-28 97.4 0.2 8.1e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP RNA_pol_Rpb2_6 PF00562.23 KFO96984.1 - 4.6e-115 384.4 0.0 6.5e-115 383.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.11 KFO96984.1 - 4.4e-24 84.0 0.0 1e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.10 KFO96984.1 - 5.1e-20 71.2 0.1 9.5e-20 70.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KFO96984.1 - 4e-19 68.6 0.0 1.7e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 KFO96984.1 - 5.8e-19 67.7 0.0 1.4e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 KFO96984.1 - 1.6e-13 50.5 0.0 2.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 KFO96984.1 - 0.00016 21.5 0.0 0.00065 19.6 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 TTL PF03133.10 KFO96985.1 - 1.2e-75 254.1 0.1 2.9e-75 252.9 0.0 1.5 1 1 1 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFO96985.1 - 6.4e-06 25.1 0.0 1.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp DUF2732 PF10809.3 KFO96985.1 - 0.019 14.5 0.1 0.097 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) ATP-grasp_3 PF02655.9 KFO96985.1 - 0.067 13.0 0.0 0.91 9.3 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain CTD_bind PF04818.8 KFO96985.1 - 0.073 13.3 0.2 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Sugar_tr PF00083.19 KFO96986.1 - 2.7e-33 115.2 22.3 3.7e-33 114.8 15.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFO96986.1 - 3.9e-31 108.0 26.1 5.3e-31 107.6 18.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFO96986.1 - 0.0048 15.3 11.4 0.0048 15.3 7.9 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 KFO96986.1 - 0.071 11.2 11.0 0.0069 14.6 4.2 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 KFO96987.1 - 4.6e-34 117.7 0.0 7.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO96987.1 - 7.1e-20 71.1 0.0 1.1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Nop14 PF04147.7 KFO96987.1 - 1.3 6.8 18.2 2.5 5.9 12.6 1.5 1 0 0 1 1 1 0 Nop14-like family VID27 PF08553.5 KFO96987.1 - 6.4 4.8 9.5 11 4.1 6.6 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein AMP-binding PF00501.23 KFO96988.1 - 7.2e-95 317.8 0.1 8.5e-95 317.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO96988.1 - 1.5e-20 73.9 1.8 3.2e-20 72.8 0.4 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 KFO96988.1 - 0.11 12.2 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Str_synth PF03088.11 KFO96989.1 - 7.6e-29 99.5 0.2 2.6e-28 97.8 0.0 2.0 3 0 0 3 3 3 1 Strictosidine synthase SGL PF08450.7 KFO96989.1 - 2.4e-14 53.3 0.0 3.6e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 KFO96989.1 - 0.00038 19.9 0.0 0.093 12.1 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain Arylesterase PF01731.15 KFO96989.1 - 0.0004 20.3 0.0 0.051 13.5 0.0 2.8 2 1 0 2 2 2 1 Arylesterase NHL PF01436.16 KFO96989.1 - 0.0018 18.0 0.1 0.12 12.4 0.0 3.5 4 0 0 4 4 4 1 NHL repeat PQQ_3 PF13570.1 KFO96989.1 - 0.053 13.8 0.3 2.8 8.3 0.0 3.3 4 1 0 4 4 4 0 PQQ-like domain Cystatin PF00031.16 KFO96990.1 - 1.6e-20 73.0 0.0 1.9e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Cystatin domain YmzC PF14157.1 KFO96990.1 - 0.018 14.8 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 YmzC-like protein Dispanin PF04505.7 KFO96991.1 - 2.5e-23 81.4 0.0 4e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein T-box PF00907.17 KFO96992.1 - 5.9e-46 156.2 0.0 8e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 T-box PDEase_I PF00233.14 KFO96993.1 - 1e-65 221.8 0.0 2e-65 220.8 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFO96993.1 - 7.3e-36 123.6 0.0 1.7e-25 89.9 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFO96993.1 - 2.7e-21 75.9 0.0 2.7e-13 50.1 0.0 2.7 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 KFO96993.1 - 1.2e-13 51.7 0.0 5.9e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 GAF domain HD PF01966.17 KFO96993.1 - 0.07 13.1 0.2 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 HD domain KH_1 PF00013.24 KFO96994.1 - 7.1e-06 25.5 1.8 1.8e-05 24.2 0.4 2.2 2 1 0 2 2 2 1 KH domain KH_3 PF13014.1 KFO96994.1 - 9.9e-05 21.8 0.1 0.00023 20.7 0.0 1.6 1 0 0 1 1 1 1 KH domain RVT_1 PF00078.22 KFO96995.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CTNNB1_binding PF08347.6 KFO96997.1 - 8.3e-46 156.8 10.7 8.3e-46 156.8 7.4 2.3 2 1 0 2 2 2 1 N-terminal CTNNB1 binding HMG_box PF00505.14 KFO96997.1 - 8.5e-22 77.2 0.7 8.5e-22 77.2 0.5 2.5 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO96997.1 - 2.2e-08 34.3 0.5 6.4e-08 32.8 0.3 1.8 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KFO96997.1 - 0.029 13.7 0.1 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 3HCDH_N PF02737.13 KFO96998.1 - 2.6e-53 180.3 1.3 3.3e-53 180.0 0.9 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFO96998.1 - 6.1e-35 119.5 0.0 1.4e-34 118.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DHC_N2 PF08393.8 KFO96998.1 - 0.056 11.9 0.0 0.076 11.5 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Ribosomal_L22 PF00237.14 KFO96998.1 - 0.082 12.8 0.2 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e p450 PF00067.17 KFO96999.1 - 8.5e-106 354.2 0.4 1e-105 353.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAP2_C PF14360.1 KFO97000.1 - 5.6e-30 103.4 14.4 5.6e-30 103.4 10.0 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 KFO97000.1 - 1.6e-06 27.8 9.1 1.6e-06 27.8 6.3 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KFO97000.1 - 4e-05 23.2 6.7 4e-05 23.2 4.6 1.9 2 1 0 2 2 2 1 PAP2 superfamily APS_kinase PF01583.15 KFO97001.1 - 1.7e-74 248.6 0.0 2.7e-74 248.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 KFO97001.1 - 1.1e-68 230.7 0.1 1.6e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 KFO97001.1 - 7.2e-49 165.2 0.0 1.5e-48 164.2 0.0 1.6 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KFO97001.1 - 8.3e-10 38.6 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFO97001.1 - 3.5e-07 31.0 0.1 2.4e-06 28.3 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFO97001.1 - 0.00027 21.2 0.0 0.00078 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFO97001.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 KFO97001.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase Zeta_toxin PF06414.7 KFO97001.1 - 0.031 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.13 KFO97001.1 - 0.075 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PRK PF00485.13 KFO97001.1 - 0.087 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 KFO97001.1 - 0.089 12.4 0.0 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFO97001.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 KFO97001.1 - 0.11 12.4 0.1 0.75 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain Prokineticin PF06607.6 KFO97002.1 - 0.017 15.1 7.2 0.022 14.8 5.0 1.1 1 0 0 1 1 1 0 Prokineticin Toxin_21 PF08091.6 KFO97002.1 - 0.018 14.7 2.5 0.018 14.7 1.8 2.1 2 0 0 2 2 2 0 Spider insecticidal peptide PilI PF10623.4 KFO97002.1 - 0.14 12.0 1.8 0.26 11.2 1.2 1.7 1 1 0 1 1 1 0 Plasmid conjugative transfer protein PilI CarbpepA_inh PF02977.10 KFO97002.1 - 2.4 7.8 9.7 0.049 13.2 1.8 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Ste5 PF11610.3 KFO97003.1 - 0.8 9.2 33.1 33 4.1 0.1 8.4 8 1 0 9 9 9 0 Scaffold protein Ste5-Fus5 binding region AIG1 PF04548.11 KFO97004.1 - 4e-26 91.4 0.0 5.1e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 KFO97004.1 - 0.0023 17.8 0.0 0.0063 16.4 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFO97004.1 - 0.023 14.1 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T4_Gp59_C PF08994.5 KFO97004.1 - 0.086 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term RNase_P_Rpp14 PF01900.14 KFO97004.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Rpp14/Pop5 family tRNA_bind PF01588.15 KFO97005.1 - 9.7e-31 105.4 0.6 5.1e-30 103.1 0.1 2.2 2 0 0 2 2 2 1 Putative tRNA binding domain NUDE_C PF04880.8 KFO97005.1 - 8.8e-05 22.9 1.5 0.00014 22.2 1.1 1.4 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region DUF972 PF06156.8 KFO97005.1 - 0.032 14.5 3.2 0.032 14.5 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_60s PF00428.14 KFO97005.1 - 0.037 14.4 7.3 0.097 13.0 5.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein GAGA_bind PF06217.7 KFO97005.1 - 0.41 10.5 4.3 0.57 10.0 3.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RabGAP-TBC PF00566.13 KFO97006.1 - 3.9e-48 163.7 0.1 6.2e-48 163.1 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 KFO97006.1 - 2.8e-36 125.0 0.0 4.1e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97006.1 - 1.5e-26 93.0 0.0 2.5e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.15 KFO97006.1 - 3.5e-16 59.5 0.0 6.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.1 KFO97006.1 - 4.5e-07 29.1 0.0 7.8e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO97006.1 - 0.26 10.3 0.1 0.48 9.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAM PF00629.18 KFO97007.1 - 1e-24 87.1 0.0 2.1e-24 86.0 0.0 1.6 1 1 0 1 1 1 1 MAM domain EGF_CA PF07645.10 KFO97007.1 - 8.4e-24 83.2 63.7 1.6e-10 40.7 2.6 5.7 4 2 1 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.2 KFO97007.1 - 6.5e-18 64.0 43.9 3.3e-07 29.7 0.9 5.8 5 0 0 5 5 5 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFO97007.1 - 3e-11 43.2 74.6 4.9e-06 26.5 4.7 5.6 4 1 1 5 5 5 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFO97007.1 - 3.8e-06 26.7 72.0 0.015 15.2 1.0 6.3 5 1 0 5 5 5 5 EGF-like domain EGF_3 PF12947.2 KFO97007.1 - 2.5e-05 24.1 67.1 3.3e-05 23.7 9.0 5.9 5 1 0 5 5 5 3 EGF domain hEGF PF12661.2 KFO97007.1 - 0.017 15.1 4.8 0.017 15.1 3.3 6.2 6 0 0 6 6 6 0 Human growth factor-like EGF EGF_2 PF07974.8 KFO97007.1 - 0.018 15.2 15.1 0.018 15.2 10.4 6.0 5 1 0 5 5 5 0 EGF-like domain EGF_MSP1_1 PF12946.2 KFO97007.1 - 0.19 11.5 36.6 0.08 12.7 4.8 4.7 4 0 0 4 4 4 0 MSP1 EGF domain 1 Methyltransf_32 PF13679.1 KFO97008.1 - 2e-13 50.2 0.3 3.9e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO97008.1 - 2.2e-09 37.1 0.0 4.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.9 KFO97008.1 - 3.3e-07 29.8 0.8 0.011 14.9 0.0 2.7 1 1 1 2 2 2 2 Methyltransferase TRM13 Methyltransf_18 PF12847.2 KFO97008.1 - 2.1e-06 28.3 0.0 1e-05 26.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.10 KFO97008.1 - 7.2e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.9 KFO97008.1 - 0.00042 19.7 0.0 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KFO97008.1 - 0.0027 16.7 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFO97008.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GST_C_2 PF13410.1 KFO97008.1 - 0.016 15.1 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ubie_methyltran PF01209.13 KFO97008.1 - 0.019 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KFO97008.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase BAR PF03114.13 KFO97010.1 - 3e-29 102.1 3.6 6.7e-29 101.0 2.5 1.6 1 0 0 1 1 1 1 BAR domain RhoGEF PF00621.15 KFO97010.1 - 2.2e-14 53.7 0.1 2.2e-14 53.7 0.1 2.8 3 0 0 3 3 3 1 RhoGEF domain SH3_2 PF07653.12 KFO97010.1 - 1.5e-13 50.0 0.0 9.4e-06 25.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFO97010.1 - 2.4e-10 39.6 0.1 2.7e-08 33.0 0.1 2.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFO97010.1 - 6e-10 38.5 0.2 3.6e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 KFO97010.1 - 0.12 12.6 0.6 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain RhoGEF PF00621.15 KFO97011.1 - 1.4e-21 77.1 0.2 2e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain Pyrophosphatase PF00719.14 KFO97012.1 - 4.1e-54 182.2 0.6 5.2e-54 181.9 0.4 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Tet_JBP PF12851.2 KFO97013.1 - 3.2e-85 283.7 1.4 4.7e-85 283.1 0.3 1.8 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily 7tm_1 PF00001.16 KFO97014.1 - 2.3e-63 213.7 21.0 3e-63 213.3 14.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97014.1 - 3.9e-11 42.6 20.3 5.1e-11 42.2 14.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PsbX PF06596.6 KFO97014.1 - 9.2 6.0 9.2 0.37 10.4 1.4 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) adh_short_C2 PF13561.1 KFO97015.1 - 4e-29 102.0 0.2 4.6e-29 101.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFO97015.1 - 1.3e-22 80.4 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFO97015.1 - 5.9e-05 22.8 0.1 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFO97015.1 - 0.00025 21.1 0.1 0.00026 21.0 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFO97015.1 - 0.0016 17.5 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KFO97015.1 - 0.0038 16.6 0.0 0.007 15.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KFO97015.1 - 0.0063 16.1 0.1 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFO97015.1 - 0.01 15.2 0.1 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transglut_core2 PF13369.1 KFO97015.1 - 0.036 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily ADH_zinc_N PF00107.21 KFO97015.1 - 0.05 13.1 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KFO97015.1 - 0.073 12.6 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UPF0146 PF03686.8 KFO97015.1 - 0.084 12.6 0.1 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) MIF4G PF02854.14 KFO97016.1 - 1.6e-27 96.2 3.2 3.9e-27 95.0 1.7 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KFO97016.1 - 5.3e-22 77.6 1.2 1.3e-21 76.3 0.9 1.7 1 0 0 1 1 1 1 MA3 domain zf-met PF12874.2 KFO97017.1 - 1.3e-29 101.4 24.7 4.1e-08 33.1 1.4 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO97017.1 - 6.6e-25 86.6 20.1 2.7e-07 30.5 1.7 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFO97017.1 - 7.9e-10 38.7 9.8 0.12 12.5 0.2 4.2 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFO97017.1 - 1.7e-09 37.0 12.2 0.013 15.0 0.0 4.3 4 0 0 4 4 4 4 U1 zinc finger AKAP95 PF04988.7 KFO97017.1 - 9.4e-08 32.0 5.6 0.09 12.5 0.1 4.2 4 0 0 4 4 4 3 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.7 KFO97017.1 - 0.0016 18.0 11.0 0.29 10.8 0.7 4.2 4 0 0 4 4 4 1 DBF zinc finger Elf1 PF05129.8 KFO97017.1 - 0.073 12.7 6.4 4 7.2 0.1 3.9 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 KFO97017.1 - 0.5 10.8 15.5 3.9 7.9 1.0 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type C1_1 PF00130.17 KFO97017.1 - 1 9.1 4.9 17 5.2 0.0 3.8 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_4 PF13894.1 KFO97017.1 - 1.6 9.2 13.0 23 5.5 0.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Eapp_C PF10238.4 KFO97017.1 - 2.3 8.1 12.9 0.14 12.0 3.2 2.9 2 1 1 3 3 3 0 E2F-associated phosphoprotein CRAL_TRIO_2 PF13716.1 KFO97019.1 - 1.3e-10 41.3 0.0 2.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spectrin PF00435.16 KFO97019.1 - 0.00017 21.8 25.7 0.00033 20.9 0.3 4.7 4 1 1 5 5 5 2 Spectrin repeat Arch_ATPase PF01637.13 KFO97019.1 - 0.0025 17.5 0.2 0.005 16.5 0.1 1.5 1 0 0 1 1 1 1 Archaeal ATPase Spectrin PF00435.16 KFO97020.1 - 0.14 12.4 14.4 1.5 9.1 2.4 3.2 3 0 0 3 3 3 0 Spectrin repeat ApoLp-III PF07464.6 KFO97020.1 - 0.48 10.4 5.3 1 9.3 0.3 2.5 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Spectrin PF00435.16 KFO97021.1 - 0.032 14.5 4.3 0.35 11.1 0.6 2.6 2 1 0 2 2 2 0 Spectrin repeat I-set PF07679.11 KFO97022.1 - 3.9e-12 45.8 0.0 5.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97022.1 - 4.5e-05 23.4 0.0 7.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO97022.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO97022.1 - 0.0075 16.1 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain fn3 PF00041.16 KFO97023.1 - 3.2e-100 328.4 0.2 7.2e-18 64.5 0.0 7.5 8 0 0 8 8 7 7 Fibronectin type III domain I-set PF07679.11 KFO97023.1 - 1.1e-24 86.1 1.5 1.8e-12 46.9 0.0 3.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97023.1 - 2.5e-06 27.5 0.0 0.018 15.1 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFO97023.1 - 5.7e-05 22.9 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain Tissue_fac PF01108.12 KFO97023.1 - 6.3e-05 22.6 0.0 1.5 8.5 0.0 6.0 6 1 0 6 6 6 1 Tissue factor SusE PF14292.1 KFO97023.1 - 0.0033 17.2 0.0 91 2.8 0.0 5.0 5 1 1 6 6 6 0 SusE outer membrane protein RL11D PF11088.3 KFO97023.1 - 0.011 15.5 0.0 17 5.2 0.0 3.8 3 0 0 3 3 3 0 Glycoprotein encoding membrane proteins RL5A and RL6 Y_Y_Y PF07495.8 KFO97023.1 - 0.015 15.0 0.0 8.3 6.2 0.0 4.5 5 0 0 5 5 5 0 Y_Y_Y domain Reeler PF02014.11 KFO97023.1 - 0.017 15.4 0.0 25 5.1 0.0 4.1 5 0 0 5 5 5 0 Reeler domain MIB_HERC2 PF06701.8 KFO97023.1 - 0.072 13.0 2.2 17 5.4 0.1 3.6 3 0 0 3 3 3 0 Mib_herc2 PhoD PF09423.5 KFO97023.1 - 0.15 10.5 0.0 30 3.0 0.0 3.4 4 0 0 4 4 4 0 PhoD-like phosphatase fn3 PF00041.16 KFO97024.1 - 5.3e-105 343.7 5.0 5e-22 77.8 0.1 7.3 7 0 0 7 7 7 7 Fibronectin type III domain I-set PF07679.11 KFO97024.1 - 7.8e-35 118.6 1.1 5.5e-15 54.9 0.0 4.5 5 0 0 5 5 5 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97024.1 - 8.4e-13 48.2 0.0 3e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFO97024.1 - 5.6e-09 35.9 0.0 0.0034 17.4 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain SusE PF14292.1 KFO97024.1 - 4.3e-08 33.0 0.5 0.032 14.0 0.0 5.3 5 0 0 5 5 5 2 SusE outer membrane protein Tissue_fac PF01108.12 KFO97024.1 - 8.7e-08 31.8 0.0 0.011 15.4 0.0 5.0 5 0 0 5 5 5 1 Tissue factor Ig_3 PF13927.1 KFO97024.1 - 9.5e-06 26.0 0.0 0.027 14.9 0.0 3.5 3 0 0 3 3 2 2 Immunoglobulin domain V-set PF07686.12 KFO97024.1 - 0.00031 20.6 0.0 0.24 11.2 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin V-set domain Receptor_2B4 PF11465.3 KFO97024.1 - 0.0077 16.1 0.1 17 5.3 0.0 4.5 4 1 1 5 5 5 0 Natural killer cell receptor 2B4 Herpes_gE PF02480.11 KFO97024.1 - 0.025 12.8 0.0 0.067 11.4 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Lipocalin_7 PF14651.1 KFO97024.1 - 0.027 14.1 0.0 3.8 7.2 0.0 3.1 3 0 0 3 3 3 0 Lipocalin / cytosolic fatty-acid binding protein family SLAM PF06214.6 KFO97024.1 - 0.062 13.2 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein C2-set_2 PF08205.7 KFO97024.1 - 0.086 12.7 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Herpes_gI PF01688.12 KFO97024.1 - 0.2 10.7 0.0 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein I I-set PF07679.11 KFO97025.1 - 7.6e-09 35.3 0.0 7.8e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97025.1 - 0.002 18.1 0.0 0.0021 18.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFO97026.1 - 7e-08 32.2 0.0 7.3e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97026.1 - 0.00094 19.2 0.0 0.001 19.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFO97026.1 - 0.062 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFO97027.1 - 5e-07 29.4 0.0 5.3e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFO97027.1 - 0.0089 16.5 0.0 0.0091 16.4 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFO97027.1 - 0.027 14.5 0.0 0.031 14.3 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain ig PF00047.20 KFO97027.1 - 0.067 13.3 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFO97028.1 - 2.5e-07 30.4 0.0 2.6e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97028.1 - 0.07 13.2 0.0 0.075 13.1 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFO97029.1 - 4.3e-07 29.7 0.0 4.4e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFO97029.1 - 0.0097 16.0 0.0 0.011 15.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFO97029.1 - 0.048 13.7 0.0 0.055 13.5 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFO97030.1 - 5.9e-09 35.6 0.0 6.1e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97030.1 - 0.0026 17.8 0.0 0.0027 17.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO97030.1 - 0.031 14.3 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFO97031.1 - 1.1e-09 38.0 0.0 1.1e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97031.1 - 0.0006 19.8 0.1 0.00063 19.8 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO97031.1 - 0.00063 19.8 0.0 0.00077 19.5 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO97031.1 - 0.0046 16.8 0.1 0.0046 16.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO97031.1 - 0.051 14.0 0.0 0.054 14.0 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFO97032.1 - 3.4e-06 26.8 0.0 3.6e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain I-set PF07679.11 KFO97033.1 - 2.6e-07 30.3 0.0 2.9e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97033.1 - 0.016 15.2 0.0 0.018 15.1 0.0 1.0 1 0 0 1 1 1 0 Immunoglobulin domain C2-set_2 PF08205.7 KFO97033.1 - 0.051 13.4 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFO97034.1 - 1.7e-77 255.3 8.9 2.4e-26 91.3 0.1 5.3 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97034.1 - 1.3e-30 105.3 6.8 2.7e-08 33.7 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFO97034.1 - 6.5e-29 99.8 1.8 6.2e-09 35.8 0.0 5.9 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFO97034.1 - 1.3e-26 92.7 9.6 1.4e-07 31.3 0.0 6.5 5 2 0 5 5 5 5 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO97034.1 - 6.8e-19 68.1 6.5 1.5e-08 34.9 0.1 5.6 5 0 0 5 5 5 4 Immunoglobulin domain C2-set_2 PF08205.7 KFO97034.1 - 4.3e-09 36.1 1.9 0.0051 16.6 0.1 5.6 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 KFO97034.1 - 1.7e-07 31.0 3.1 1.9 8.4 0.0 4.8 4 1 0 4 4 4 3 Natural killer cell receptor 2B4 C1-set PF07654.10 KFO97034.1 - 4.9e-07 29.6 1.5 0.004 17.1 0.0 5.0 4 1 0 4 4 4 1 Immunoglobulin C1-set domain DUF2914 PF11141.3 KFO97034.1 - 0.23 11.0 3.7 5.1 6.6 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2914) PH PF00169.24 KFO97035.1 - 2.3e-08 34.1 0.0 5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFO97035.1 - 2.6e-05 24.2 0.0 7.1e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KFO97035.1 - 3e-05 24.2 0.1 0.00014 22.0 0.0 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain DNA_pol3_delta2 PF13177.1 KFO97035.1 - 0.048 13.3 0.5 0.074 12.7 0.4 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PH_6 PF15406.1 KFO97035.1 - 0.056 13.4 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Cmc1 PF08583.5 KFO97035.1 - 0.18 11.5 1.8 6.2 6.6 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like FKBP_C PF00254.23 KFO97036.1 - 4.1e-30 103.6 0.0 6.2e-30 103.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.1 KFO97036.1 - 1.5e-07 31.4 0.1 2.4e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFO97036.1 - 8.3e-07 28.0 0.9 0.0011 18.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFO97036.1 - 8.3e-07 28.3 1.8 0.044 13.6 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFO97036.1 - 1e-06 27.6 1.3 0.0063 15.7 0.1 2.5 2 0 0 2 2 2 2 EF hand Gasdermin PF04598.7 KFO97037.1 - 6.2e-18 64.7 0.0 7.1e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Gasdermin family Oxysterol_BP PF01237.13 KFO97038.1 - 1.3e-133 444.9 0.0 1.3e-133 444.9 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KFO97038.1 - 6.8e-13 48.4 0.2 1.5e-12 47.3 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFO97038.1 - 6.6e-06 26.3 0.3 0.00025 21.2 0.2 3.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFO97038.1 - 2.3e-05 24.5 0.5 0.00012 22.2 0.4 2.2 1 1 0 1 1 1 1 PH domain AAA_27 PF13514.1 KFO97038.1 - 0.016 12.9 1.6 1.9 6.0 0.5 2.1 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 KFO97039.1 - 8.8e-45 150.2 0.0 1.7e-14 53.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO97039.1 - 2e-28 98.1 0.0 2.2e-08 33.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO97039.1 - 2.3e-28 97.8 0.1 1.2e-10 41.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO97039.1 - 2.5e-06 27.2 0.0 0.024 14.4 0.0 3.6 4 0 0 4 4 4 1 RNA binding motif RNA_bind PF08675.6 KFO97039.1 - 0.00073 19.4 0.0 0.54 10.2 0.0 2.6 2 0 0 2 2 2 2 RNA binding domain Nup35_RRM_2 PF14605.1 KFO97039.1 - 0.0013 18.4 0.1 14 5.5 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif TPR_11 PF13414.1 KFO97040.1 - 1.5e-14 53.3 7.0 1.7e-08 33.9 0.1 4.6 4 1 1 5 5 5 3 TPR repeat TPR_1 PF00515.23 KFO97040.1 - 4.5e-12 45.0 8.3 0.041 13.4 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97040.1 - 1.3e-11 44.6 0.4 0.001 19.3 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFO97040.1 - 2.2e-11 42.7 9.4 0.057 13.3 0.0 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFO97040.1 - 6.2e-09 35.6 7.6 0.0062 16.4 0.0 5.8 4 2 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO97040.1 - 4.1e-08 33.2 11.0 0.001 19.1 0.2 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFO97040.1 - 1.2e-05 24.6 1.9 0.61 9.9 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFO97040.1 - 1.6e-05 24.6 0.1 0.17 11.8 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97040.1 - 0.00017 22.1 2.2 7.7 7.3 0.0 5.1 4 3 1 5 5 5 2 Tetratricopeptide repeat DUF285 PF03382.9 KFO97040.1 - 0.00074 19.0 3.4 0.0027 17.2 0.9 2.1 1 1 1 2 2 2 2 Mycoplasma protein of unknown function, DUF285 TPR_14 PF13428.1 KFO97040.1 - 0.0013 19.1 0.0 23 5.9 0.0 5.8 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFO97040.1 - 0.0019 17.8 0.5 7.9 6.5 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO97040.1 - 0.0043 17.4 3.5 19 6.0 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFO97040.1 - 0.011 15.6 2.2 0.049 13.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 KFO97040.1 - 0.047 13.5 2.0 12 5.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 KFO97040.1 - 0.12 11.5 6.5 0.7 8.9 0.6 2.5 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP FAD-oxidase_C PF02913.14 KFO97041.1 - 7e-59 199.1 0.0 9.7e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFO97041.1 - 8.9e-38 128.9 0.0 6e-37 126.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KFO97041.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like GST_C_3 PF14497.1 KFO97044.1 - 1.5e-12 47.8 0.0 2.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 KFO97044.1 - 4.7e-07 29.8 0.5 0.0052 16.6 0.0 2.7 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_2 PF13410.1 KFO97044.1 - 4.1e-06 26.5 0.0 9.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KFO97044.1 - 5.1e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.20 KFO97044.1 - 0.03 14.2 0.6 0.047 13.6 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Homeobox PF00046.24 KFO97045.1 - 3.6e-22 77.7 8.8 3.6e-22 77.7 6.1 1.8 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFO97045.1 - 0.025 14.2 1.1 0.051 13.2 0.7 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFO97046.1 - 2.6e-21 74.9 9.5 3.3e-21 74.6 4.1 2.4 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFO97046.1 - 0.036 13.7 0.2 0.036 13.7 0.2 2.6 3 0 0 3 3 3 0 Homeobox KN domain DUF3528 PF12045.3 KFO97047.1 - 6.7e-68 227.3 1.3 1.1e-67 226.5 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeobox PF00046.24 KFO97047.1 - 9.2e-21 73.2 8.1 1.7e-20 72.3 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO97047.1 - 0.084 12.5 0.3 0.22 11.2 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFO97048.1 - 1.8e-20 72.2 10.7 2e-20 72.1 7.4 1.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFO97048.1 - 0.00017 20.5 0.2 0.00018 20.4 0.1 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFO97048.1 - 0.026 14.2 3.2 0.052 13.2 2.2 1.7 1 1 0 1 1 1 0 Homeobox KN domain Daxx PF03344.10 KFO97048.1 - 0.44 8.9 5.3 0.5 8.7 3.7 1.0 1 0 0 1 1 1 0 Daxx Family Homeobox PF00046.24 KFO97049.1 - 4.8e-19 67.7 6.0 5.7e-19 67.4 4.2 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO97049.1 - 0.0012 18.4 2.7 0.0019 17.8 1.9 1.5 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFO97049.1 - 0.031 13.3 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_23 PF13384.1 KFO97049.1 - 0.034 13.7 0.1 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFO97050.1 - 0.0015 18.1 2.4 0.003 17.1 1.7 1.5 1 0 0 1 1 1 1 Homeobox domain DUF2296 PF10058.4 KFO97051.1 - 5.7e-22 77.2 0.3 8.6e-22 76.6 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) 7tm_7 PF08395.7 KFO97051.1 - 0.0011 18.0 0.4 0.0014 17.7 0.2 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor ATP-synt_C PF00137.16 KFO97052.1 - 1.6e-17 63.1 13.7 2e-17 62.8 9.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit C WxL PF13731.1 KFO97052.1 - 0.019 14.8 0.1 0.023 14.5 0.1 1.0 1 0 0 1 1 1 0 WxL domain surface cell wall-binding bZIP_1 PF00170.16 KFO97053.1 - 2.9e-12 46.3 7.7 4.8e-12 45.6 5.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFO97053.1 - 2.5e-10 40.0 5.3 6.2e-10 38.7 3.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFO97053.1 - 0.0036 17.5 7.7 0.0087 16.3 5.3 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor ERM PF00769.14 KFO97053.1 - 0.022 14.2 3.7 0.043 13.3 2.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Shugoshin_N PF07558.6 KFO97053.1 - 0.035 13.8 2.3 0.15 11.7 0.3 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region zf-C2H2_4 PF13894.1 KFO97053.1 - 0.038 14.3 0.8 0.08 13.3 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO97053.1 - 0.044 14.1 1.3 0.089 13.1 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type RhoGAP PF00620.22 KFO97054.1 - 7e-50 168.5 0.0 1.2e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 KFO97054.1 - 2.1e-15 56.2 7.9 3.6e-15 55.4 5.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.19 KFO97054.1 - 1.2e-14 53.8 0.1 2.5e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 SH2 domain FYVE_2 PF02318.11 KFO97054.1 - 0.014 15.2 1.9 0.028 14.3 1.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.1 KFO97054.1 - 0.058 12.7 1.5 0.13 11.6 1.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KFO97054.1 - 0.074 13.0 5.1 0.17 11.9 3.5 1.6 1 0 0 1 1 1 0 RING-like domain Neur_chan_LBD PF02931.18 KFO97055.1 - 8.1e-71 237.6 1.9 1.1e-70 237.1 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFO97055.1 - 3.1e-63 213.8 9.6 4.3e-49 167.5 5.3 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 KFO97056.1 - 1.7e-20 72.7 22.7 2.8e-13 48.9 5.3 3.0 2 2 1 3 3 3 2 Membrane transport protein DEP PF00610.16 KFO97056.1 - 4.1e-13 48.8 0.0 9.3e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2207 PF09972.4 KFO97056.1 - 5.3 5.5 0.0 5.3 5.5 0.0 3.8 3 1 0 4 4 4 0 Predicted membrane protein (DUF2207) Peptidase_C69 PF03577.10 KFO97057.1 - 3.2e-09 36.1 0.1 4.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.11 KFO97057.1 - 0.0012 18.2 0.0 0.011 15.1 0.0 2.3 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase YchF-GTPase_C PF06071.8 KFO97058.1 - 5.4e-41 138.2 1.0 5.4e-41 138.2 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KFO97058.1 - 8.8e-19 67.5 0.0 3.6e-18 65.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFO97058.1 - 1.9e-07 30.5 0.0 4.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KFO97058.1 - 0.0019 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain AAA_17 PF13207.1 KFO97058.1 - 0.0023 18.7 0.8 0.082 13.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 KFO97058.1 - 0.0046 15.7 0.0 0.0099 14.6 0.0 1.5 1 0 0 1 1 1 1 ArgK protein Dynamin_N PF00350.18 KFO97058.1 - 0.03 14.1 0.0 8.7 6.1 0.0 2.6 1 1 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 KFO97058.1 - 0.058 12.8 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KFO97058.1 - 0.078 13.2 1.1 1.4 9.2 0.0 3.0 3 1 0 3 3 3 0 AAA domain zf-C2H2 PF00096.21 KFO97059.1 - 1.6e-05 24.9 2.2 1.6e-05 24.9 1.5 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97059.1 - 0.00029 20.9 1.2 0.00029 20.9 0.9 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO97059.1 - 0.0014 18.8 1.3 0.0014 18.8 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.7 KFO97059.1 - 0.5 10.5 3.4 1.1 9.4 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pkinase_Tyr PF07714.12 KFO97060.1 - 4.2e-64 216.1 0.0 7.9e-64 215.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO97060.1 - 1.6e-59 201.2 0.0 3.8e-59 199.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.12 KFO97060.1 - 7e-10 38.6 0.1 6.4e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFO97060.1 - 5e-09 36.1 4.2 1.2e-08 35.0 0.2 3.2 4 0 0 4 4 4 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFO97060.1 - 0.0062 16.2 0.8 0.018 14.8 0.1 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Sugarporin_N PF11471.3 KFO97060.1 - 4.2 7.1 7.6 9.1 6.0 5.3 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension RasGEF PF00617.14 KFO97061.1 - 2.9e-69 232.5 2.8 2.9e-69 232.5 1.9 1.7 2 0 0 2 2 2 1 RasGEF domain cNMP_binding PF00027.24 KFO97061.1 - 5.5e-36 122.2 0.0 2.1e-17 62.6 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DEP PF00610.16 KFO97061.1 - 2.4e-22 78.4 2.0 5.9e-22 77.2 0.5 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RasGEF_N PF00618.15 KFO97061.1 - 1.8e-12 47.2 0.0 7.8e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif RA PF00788.18 KFO97061.1 - 4.1e-05 23.9 0.0 0.00013 22.3 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 KFO97062.1 - 1e-13 51.2 2.5 2.2e-13 50.1 1.1 2.1 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 KFO97062.1 - 1.8e-09 37.2 0.5 4.5e-09 36.0 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFO97062.1 - 3.5e-07 30.2 1.1 3.5e-07 30.2 0.8 2.4 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFO97062.1 - 0.00028 20.5 1.7 0.00063 19.4 1.2 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PsbU PF06514.6 KFO97062.1 - 0.002 17.9 2.0 0.0055 16.5 0.1 2.8 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) SlyX PF04102.7 KFO97062.1 - 2.5 8.5 12.5 0.15 12.4 2.1 3.7 3 0 0 3 3 3 0 SlyX DUF2407_C PF13373.1 KFO97062.1 - 9.7 6.1 9.5 0.93 9.4 2.6 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain BCDHK_Adom3 PF10436.4 KFO97063.1 - 8.7e-54 181.4 0.0 1.3e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFO97063.1 - 1.6e-21 76.1 0.0 2.9e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFO97063.1 - 0.00066 19.3 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KFO97063.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Integrin_alpha2 PF08441.7 KFO97064.1 - 9.1e-116 387.3 4.3 1.3e-115 386.9 3.0 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 KFO97064.1 - 3.3e-17 61.6 21.5 1.7e-07 30.6 4.3 3.8 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 KFO97064.1 - 4.2e-14 52.6 9.7 1.2e-10 41.6 1.7 3.0 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella LRR19-TM PF15176.1 KFO97064.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Homeobox PF00046.24 KFO97065.1 - 7.3e-21 73.5 3.2 1.3e-20 72.7 2.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO97065.1 - 0.016 14.8 0.2 0.065 12.9 0.0 2.1 2 0 0 2 2 2 0 Homeobox KN domain Homez PF11569.3 KFO97065.1 - 0.1 11.7 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Peptidase_M24 PF00557.19 KFO97066.1 - 1.8e-49 168.1 0.0 2.4e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Hat1_N PF10394.4 KFO97067.1 - 7.4e-39 133.3 1.1 2.8e-38 131.5 0.9 1.9 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 KFO97067.1 - 0.00014 21.9 0.0 0.00082 19.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFO97067.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.22 KFO97068.1 - 1.6e-74 245.6 2.7 9.1e-27 92.6 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KFO97068.1 - 5.7e-12 44.0 3.0 0.029 13.6 0.0 5.3 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 KFO97068.1 - 2.4e-11 43.5 1.3 0.0026 17.8 0.2 4.6 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFO97068.1 - 1.9e-10 39.7 1.1 0.016 15.0 0.0 5.6 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.1 KFO97068.1 - 1e-05 25.0 0.1 0.026 14.1 0.0 4.2 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.1 KFO97068.1 - 0.00018 20.6 0.5 4.9 6.6 0.0 3.9 3 0 0 3 3 3 2 EF hand Dynein_IC2 PF11540.3 KFO97069.1 - 1.3e-18 66.0 0.4 2.3e-18 65.2 0.3 1.5 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.27 KFO97069.1 - 1.9e-15 56.0 13.0 8.7e-06 25.4 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_B561 PF03188.11 KFO97070.1 - 5.8e-39 133.0 8.6 5.8e-39 133.0 6.0 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 KFO97070.1 - 3.1e-05 23.4 11.3 0.02 14.2 7.8 2.9 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ferric_reduct PF01794.14 KFO97070.1 - 0.008 16.2 3.9 0.008 16.2 2.7 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Trp_oprn_chp PF09534.5 KFO97070.1 - 0.017 14.7 0.7 0.053 13.1 0.0 2.1 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PepSY_TM_3 PF13706.1 KFO97070.1 - 0.03 13.7 0.3 0.03 13.7 0.2 3.1 4 0 0 4 4 4 0 PepSY-associated TM helix COPI_assoc PF08507.5 KFO97070.1 - 1.3 8.7 8.2 6.4 6.4 5.7 2.3 1 1 0 1 1 1 0 COPI associated protein NfeD PF01957.13 KFO97070.1 - 1.4 9.0 5.1 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF202 PF02656.10 KFO97070.1 - 6.1 7.1 6.9 1.7e+02 2.5 4.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF4293 PF14126.1 KFO97070.1 - 7.7 6.4 8.2 14 5.5 1.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF4577 PF15145.1 KFO97071.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Methyltransf_23 PF13489.1 KFO97072.1 - 5.1e-12 45.8 0.0 9.2e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO97072.1 - 1.3e-11 44.8 0.0 3.2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO97072.1 - 1.4e-10 41.4 0.0 3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO97072.1 - 4.1e-09 36.7 0.0 9.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO97072.1 - 2.1e-07 30.6 0.1 6.3e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO97072.1 - 4.9e-06 27.0 0.0 9.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFO97072.1 - 0.00039 20.4 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KFO97072.1 - 0.0074 17.1 0.0 0.018 15.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CheR PF01739.13 KFO97072.1 - 0.034 13.4 0.0 0.53 9.5 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NodS PF05401.6 KFO97072.1 - 0.047 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.9 KFO97072.1 - 0.13 11.5 0.0 0.32 10.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 KFO97073.1 - 4e-58 196.5 0.2 1e-57 195.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97073.1 - 1e-34 119.7 0.0 2.4e-34 118.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase GRASP55_65 PF04495.9 KFO97074.1 - 2.3e-77 257.6 0.0 3e-62 208.6 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KFO97074.1 - 3.9e-05 23.4 0.0 0.052 13.4 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Pyridoxal_deC PF00282.14 KFO97075.1 - 3.9e-147 489.5 0.0 4.6e-147 489.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFO97075.1 - 4.6e-06 26.0 0.0 8.1e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFO97075.1 - 1.9e-05 23.5 0.0 0.00021 20.1 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 KFO97075.1 - 0.0046 15.4 0.0 0.0075 14.7 0.0 1.3 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) OKR_DC_1 PF01276.15 KFO97075.1 - 0.041 12.4 0.0 0.064 11.7 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.16 KFO97075.1 - 0.063 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFO97075.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C2H2 PF00096.21 KFO97076.1 - 3.6e-19 67.8 14.9 1.1e-07 31.8 0.5 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO97076.1 - 2.3e-18 65.4 20.3 2.8e-10 39.9 0.9 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO97076.1 - 1.6e-15 56.1 13.4 1.7e-06 27.9 0.9 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO97076.1 - 8.8e-07 28.8 5.8 0.052 13.7 0.5 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO97076.1 - 4.4e-06 26.6 6.7 0.0066 16.6 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFO97076.1 - 3.3e-05 23.6 6.9 0.021 14.7 0.6 3.2 3 1 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFO97076.1 - 4.3e-05 23.5 4.2 4.9e-05 23.3 1.5 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFO97076.1 - 0.00042 19.9 4.0 0.35 10.5 0.7 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-BED PF02892.10 KFO97076.1 - 0.00059 19.5 11.3 1.3 8.7 0.4 3.2 1 1 2 3 3 3 3 BED zinc finger RRN7 PF11781.3 KFO97076.1 - 0.0015 17.9 1.2 0.028 13.9 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_2 PF12756.2 KFO97076.1 - 0.0079 16.2 3.7 0.78 9.8 0.5 2.5 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) Prok-RING_4 PF14447.1 KFO97076.1 - 0.016 14.7 0.4 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.9 KFO97076.1 - 0.067 12.6 0.1 0.15 11.5 0.1 1.7 1 1 1 2 2 2 0 Rad50 zinc hook motif DUF2225 PF09986.4 KFO97076.1 - 0.074 12.5 1.0 0.075 12.4 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn_Tnp_IS1 PF03811.8 KFO97076.1 - 0.12 11.8 0.5 0.28 10.7 0.3 1.6 1 0 0 1 1 1 0 InsA N-terminal domain zf-RING_2 PF13639.1 KFO97076.1 - 0.18 11.6 2.5 0.21 11.4 1.1 1.6 1 1 1 2 2 2 0 Ring finger domain Elf1 PF05129.8 KFO97076.1 - 0.32 10.6 2.2 0.18 11.5 0.3 1.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-TRAF PF02176.13 KFO97076.1 - 0.4 11.1 3.8 0.77 10.1 1.5 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger Mcm10 PF09332.6 KFO97076.1 - 0.65 9.2 3.9 0.55 9.5 1.9 1.4 1 1 1 2 2 2 0 Mcm10 replication factor Zn_Tnp_IS1595 PF12760.2 KFO97076.1 - 1.8 8.4 6.9 2.2 8.1 0.3 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Myosin_head PF00063.16 KFO97077.1 - 5.9e-200 665.8 1.1 7.1e-200 665.5 0.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.20 KFO97077.1 - 7.4e-62 208.8 0.0 1.5e-61 207.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97077.1 - 2.9e-41 141.2 0.0 4.8e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFO97077.1 - 4.7e-07 29.7 0.0 0.017 14.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KFO97077.1 - 2e-05 23.7 0.0 5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like IQ PF00612.22 KFO97077.1 - 3.4e-05 23.0 6.7 0.0015 18.0 0.0 3.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KFO97077.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFO97077.1 - 0.067 12.2 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin MTS PF05175.9 KFO97078.1 - 8.3e-15 54.5 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFO97078.1 - 1.1e-11 44.7 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFO97078.1 - 1.5e-11 43.9 0.1 2.5e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFO97078.1 - 2.7e-10 40.0 0.2 3.6e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KFO97078.1 - 3.9e-10 39.5 0.0 5.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 KFO97078.1 - 7.9e-10 39.3 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFO97078.1 - 1.4e-08 34.3 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 KFO97078.1 - 1.5e-06 28.4 0.5 2.6e-06 27.7 0.3 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KFO97078.1 - 4.7e-06 26.2 0.1 7e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.7 KFO97078.1 - 0.00014 22.2 0.1 0.00036 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO97078.1 - 0.00035 20.9 0.1 0.00083 19.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFO97078.1 - 0.0019 17.2 0.0 0.0029 16.6 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase FmrO PF07091.6 KFO97078.1 - 0.0022 17.0 0.2 0.0035 16.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) N6_Mtase PF02384.11 KFO97078.1 - 0.0041 16.2 0.2 0.0087 15.1 0.1 1.7 1 1 0 1 1 1 1 N-6 DNA Methylase DNA_methylase PF00145.12 KFO97078.1 - 0.0045 16.1 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF2431 PF10354.4 KFO97078.1 - 0.014 15.3 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_16 PF10294.4 KFO97078.1 - 0.018 14.5 0.1 0.038 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase DUF43 PF01861.11 KFO97078.1 - 0.021 13.8 0.1 0.042 12.8 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function DUF43 Methyltransf_9 PF08003.6 KFO97078.1 - 0.049 12.3 0.4 0.072 11.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 KFO97078.1 - 0.059 13.0 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pfg27 PF09216.5 KFO97078.1 - 0.077 12.5 0.8 0.11 12.0 0.6 1.2 1 0 0 1 1 1 0 Pfg27 RRM_3 PF08777.6 KFO97079.1 - 5e-31 106.6 1.9 5e-31 106.6 1.3 3.5 3 1 0 3 3 3 1 RNA binding motif La PF05383.12 KFO97079.1 - 1.8e-24 85.2 0.1 3.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KFO97079.1 - 9.7e-15 53.9 0.3 1.4e-09 37.4 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO97079.1 - 1.6e-12 47.1 0.0 6e-08 32.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO97079.1 - 0.0013 18.4 1.9 2.5 8.0 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 KFO97079.1 - 2 7.9 14.2 18 4.8 0.0 2.4 2 1 0 2 2 2 0 IncA protein Kelch_1 PF01344.20 KFO97080.1 - 5.6e-50 166.6 30.7 3.5e-12 45.6 0.3 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFO97080.1 - 4.8e-37 124.6 13.7 2.7e-08 33.6 0.1 6.3 2 2 4 6 6 6 6 Kelch motif BTB PF00651.26 KFO97080.1 - 1.5e-30 105.4 1.2 2.4e-30 104.7 0.8 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 KFO97080.1 - 1.2e-29 101.7 3.9 2.1e-05 24.2 0.1 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain BACK PF07707.10 KFO97080.1 - 3.2e-25 87.9 3.5 3.2e-25 87.9 2.4 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFO97080.1 - 1.4e-21 75.3 16.5 0.00026 20.6 0.0 7.1 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFO97080.1 - 2.5e-19 68.8 4.9 1.5e-05 25.0 0.1 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO97080.1 - 5.1e-06 26.3 23.8 0.31 11.0 0.4 6.5 7 0 0 7 7 7 4 Kelch motif DUF3342 PF11822.3 KFO97080.1 - 8.2e-05 21.8 0.1 0.00015 21.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Put_Phosphatase PF06888.7 KFO97081.1 - 1.1e-90 302.8 0.1 1.3e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 KFO97081.1 - 1.2e-08 35.3 0.0 1.8e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KFO97081.1 - 0.037 13.7 0.4 1 8.9 0.2 2.7 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KFO97081.1 - 0.05 13.8 0.5 0.4 10.8 0.3 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Trichoplein PF13868.1 KFO97082.1 - 5.2e-13 48.1 122.1 5.2e-13 48.1 84.7 2.2 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin Pro_isomerase PF00160.16 KFO97083.1 - 1.8e-47 161.4 0.4 1.8e-47 161.4 0.3 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 KFO97083.1 - 3e-07 30.1 39.6 3e-07 30.1 27.5 5.5 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein FAST_2 PF08368.7 KFO97084.1 - 2.2e-29 101.6 0.6 3.2e-28 97.9 0.0 3.0 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 FAST_1 PF06743.10 KFO97084.1 - 8.3e-16 57.4 1.7 8.3e-16 57.4 1.2 4.5 5 0 0 5 5 5 2 FAST kinase-like protein, subdomain 1 RAP PF08373.5 KFO97084.1 - 1.6e-14 53.3 1.3 3e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 RAP domain Kelch_1 PF01344.20 KFO97085.1 - 1.2e-46 156.0 0.0 1.2e-10 40.7 0.0 5.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFO97085.1 - 1.3e-31 107.4 0.0 1.2e-09 37.8 0.0 5.6 1 1 4 5 5 5 4 Kelch motif BACK PF07707.10 KFO97085.1 - 1.4e-30 105.1 0.3 4.1e-30 103.6 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFO97085.1 - 1.5e-28 98.9 1.1 2.5e-28 98.2 0.3 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFO97085.1 - 1.1e-24 85.8 0.3 5.9e-08 32.3 0.0 5.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KFO97085.1 - 9.7e-23 79.7 0.0 1.8e-05 24.7 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFO97085.1 - 2.8e-17 61.7 0.1 0.094 12.5 0.0 5.5 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.1 KFO97085.1 - 3.2e-14 52.4 0.0 0.12 12.3 0.0 5.5 5 0 0 5 5 5 4 Kelch motif DUF3342 PF11822.3 KFO97085.1 - 0.00047 19.4 0.6 0.001 18.2 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) DUF1448 PF07289.6 KFO97086.1 - 1.1e-150 501.2 0.2 1.3e-150 501.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) bPH_3 PF14470.1 KFO97086.1 - 7.6e-07 29.3 0.1 9.7e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain GRAM PF02893.15 KFO97086.1 - 3e-05 23.4 0.0 0.004 16.6 0.0 2.5 2 0 0 2 2 2 2 GRAM domain Vps36_ESCRT-II PF11605.3 KFO97086.1 - 9.4e-05 22.1 0.1 0.23 11.2 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.8 KFO97086.1 - 0.0014 18.4 1.4 0.063 13.1 0.1 2.7 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling Collagen PF01391.13 KFO97087.1 - 7.4e-70 230.3 298.7 4e-10 39.0 15.8 12.1 2 2 6 9 9 9 8 Collagen triple helix repeat (20 copies) VWA PF00092.23 KFO97087.1 - 4.6e-64 215.3 1.0 1e-39 136.0 0.3 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KFO97087.1 - 6.3e-23 81.7 0.2 2.2e-13 50.6 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 KFO97087.1 - 6.1e-09 35.7 0.1 0.00024 20.8 0.0 3.2 3 0 0 3 3 3 2 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFO97087.1 - 0.00019 21.2 0.6 0.011 15.5 0.1 2.2 2 0 0 2 2 2 1 vWA found in TerF C terminus Ldl_recept_a PF00057.13 KFO97088.1 - 0 1088.2 692.1 2.1e-12 46.7 5.0 38.5 38 0 0 38 38 38 36 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 KFO97088.1 - 1.5e-211 684.5 101.1 4.6e-12 46.0 0.0 38.3 39 1 0 39 39 39 31 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFO97088.1 - 6e-61 202.2 330.1 3.6e-10 39.7 3.6 24.0 22 1 0 22 22 22 15 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFO97088.1 - 1.1e-24 85.7 152.3 3.2e-09 36.2 1.2 18.6 18 0 0 18 18 18 10 Complement Clr-like EGF-like SGL PF08450.7 KFO97088.1 - 2e-12 47.0 34.4 0.077 12.3 0.6 14.9 9 6 2 13 13 13 4 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KFO97088.1 - 4.3e-05 23.4 0.0 26 4.8 0.0 8.6 11 1 0 11 11 11 0 Arylesterase Lactonase PF10282.4 KFO97088.1 - 2.4 7.1 0.0 1.2e+02 1.6 0.0 3.4 4 0 0 4 4 4 0 Lactonase, 7-bladed beta-propeller adh_short PF00106.20 KFO97089.1 - 1.9e-12 47.3 0.0 2.6e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 KFO97089.1 - 4.8e-07 29.1 0.0 2.8e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 KFO97089.1 - 0.00028 20.7 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PAP2 PF01569.16 KFO97090.1 - 8.7e-13 48.0 5.9 8.7e-13 48.0 4.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF4117 PF13491.1 KFO97090.1 - 0.052 12.9 7.7 0.16 11.4 5.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) ThiW PF09512.5 KFO97090.1 - 0.35 10.6 5.9 0.094 12.5 0.9 2.2 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Spindle_Spc25 PF08234.7 KFO97091.1 - 7.2e-25 86.7 1.3 1.1e-24 86.1 0.2 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 KFO97091.1 - 0.0076 14.9 12.1 0.01 14.4 8.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Mnd1 PF03962.10 KFO97091.1 - 0.03 14.0 13.2 0.039 13.6 8.9 1.4 1 1 0 1 1 1 0 Mnd1 family Bacillus_HBL PF05791.6 KFO97091.1 - 0.037 13.4 8.8 0.077 12.3 4.9 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HIM1 PF08732.5 KFO97091.1 - 0.066 11.6 4.7 0.061 11.7 2.3 1.6 1 1 1 2 2 2 0 HIM1 CorA PF01544.13 KFO97091.1 - 0.84 8.6 9.3 1.7 7.5 6.4 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Atg14 PF10186.4 KFO97091.1 - 1.4 7.7 13.0 2.2 7.1 9.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Dynamin_N PF00350.18 KFO97091.1 - 1.7 8.4 10.6 72 3.1 7.3 2.3 1 1 0 1 1 1 0 Dynamin family DUF342 PF03961.8 KFO97091.1 - 1.9 6.8 10.3 2.2 6.5 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KFO97091.1 - 2.5 7.6 17.5 2 8.0 10.8 1.7 1 1 1 2 2 2 0 IncA protein TRAM_LAG1_CLN8 PF03798.11 KFO97092.1 - 5.6e-37 127.2 23.8 7.1e-37 126.8 16.5 1.1 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 KFO97092.1 - 3e-07 29.9 1.0 5.2e-07 29.1 0.7 1.3 1 0 0 1 1 1 1 Homeobox domain Pkinase PF00069.20 KFO97093.1 - 2.4e-62 210.4 0.0 3e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97093.1 - 1e-44 152.5 0.0 1.5e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.3 KFO97093.1 - 1.9e-12 46.5 0.0 3.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C terminal Kinase-like PF14531.1 KFO97093.1 - 0.00037 19.5 0.0 0.00068 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO97093.1 - 0.094 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO97093.1 - 0.15 11.7 0.0 0.65 9.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Galactosyl_T PF01762.16 KFO97094.1 - 8.5e-61 204.9 0.0 1.1e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Sel1 PF08238.7 KFO97095.1 - 1.5e-67 222.4 37.1 5.2e-09 36.4 0.2 12.8 12 0 0 12 12 12 11 Sel1 repeat fn2 PF00040.14 KFO97095.1 - 4.2e-19 68.2 6.4 7.8e-19 67.4 4.4 1.5 1 0 0 1 1 1 1 Fibronectin type II domain Stonin2_N PF12016.3 KFO97096.1 - 2.3e-112 375.5 31.6 3.3e-112 375.0 21.9 1.2 1 0 0 1 1 1 1 Stonin 2 Adap_comp_sub PF00928.16 KFO97096.1 - 9.7e-54 182.2 0.2 1.8e-53 181.3 0.1 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family TFIIA PF03153.8 KFO97097.1 - 2.6e-90 304.0 52.4 4.7e-64 217.6 25.5 2.6 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.8 KFO97097.1 - 0.39 11.1 12.1 0.42 11.0 0.8 2.4 2 0 0 2 2 2 0 Senescence regulator SelP_N PF04592.9 KFO97097.1 - 0.84 8.9 12.9 0.022 14.1 4.3 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Pox_Ag35 PF03286.9 KFO97097.1 - 1.6 8.2 12.2 0.43 10.0 4.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4557 PF15101.1 KFO97097.1 - 2.6 7.8 18.4 0.1 12.4 7.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) RXT2_N PF08595.6 KFO97097.1 - 3 7.6 9.9 0.39 10.4 2.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Zip PF02535.17 KFO97097.1 - 4.1 6.3 7.5 0.62 9.0 1.4 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter DHHW PF14286.1 KFO97097.1 - 5.9 6.0 12.5 1.9 7.7 1.6 2.1 2 0 0 2 2 2 0 DHHW protein Daxx PF03344.10 KFO97097.1 - 8.9 4.6 26.4 0.8 8.1 10.3 2.1 2 0 0 2 2 2 0 Daxx Family 7tm_1 PF00001.16 KFO97098.1 - 1.8e-40 138.6 20.4 2.6e-40 138.1 14.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.1 KFO97098.1 - 1e-06 28.4 0.4 0.0011 18.7 0.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat 7TM_GPCR_Srx PF10328.4 KFO97098.1 - 0.00014 21.1 14.8 0.00023 20.3 10.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx LRR_5 PF13306.1 KFO97098.1 - 0.0034 17.0 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFO97098.1 - 0.042 13.4 1.5 9 6.0 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) GnHR_trans PF12369.3 KFO97098.1 - 1.7 9.1 7.0 1.6 9.2 3.3 2.2 2 1 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region Senescence PF06911.7 KFO97099.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein DUF4200 PF13863.1 KFO97099.1 - 0.5 10.3 56.9 0.18 11.7 14.5 4.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4200) TraH PF06122.6 KFO97099.1 - 1.2 7.8 4.8 1.8 7.2 0.3 2.3 1 1 1 2 2 2 0 Conjugative relaxosome accessory transposon protein TMF_TATA_bd PF12325.3 KFO97099.1 - 4.8 6.9 59.1 0.31 10.7 0.7 5.1 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 KFO97099.1 - 5.7 6.0 17.6 1.7 7.7 0.2 3.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein CCDC155 PF14662.1 KFO97099.1 - 9.3 5.7 59.4 0.89 9.1 0.7 3.7 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 Filament PF00038.16 KFO97100.1 - 0.006 16.0 26.7 0.008 15.6 18.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.1 KFO97100.1 - 0.007 15.5 15.8 0.007 15.5 11.0 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KFO97100.1 - 0.038 13.1 2.3 0.055 12.6 1.3 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CCDC144C PF14915.1 KFO97100.1 - 0.19 10.5 31.0 0.31 9.9 21.5 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region ADIP PF11559.3 KFO97100.1 - 0.44 10.4 29.0 0.51 10.2 7.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KFO97100.1 - 0.91 8.4 22.5 1.2 8.0 15.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KFO97100.1 - 1 8.3 33.3 2.8 6.9 8.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 TIP49 PF06068.8 KFO97100.1 - 2.4 6.7 11.3 2.8 6.5 7.8 1.0 1 0 0 1 1 1 0 TIP49 C-terminus IncA PF04156.9 KFO97100.1 - 5.1 6.6 37.2 4.2 6.9 16.5 2.1 1 1 1 2 2 2 0 IncA protein YlqD PF11068.3 KFO97100.1 - 6.2 6.8 28.9 6.4 6.8 10.3 2.3 1 1 1 2 2 2 0 YlqD protein CDO_I PF05995.7 KFO97100.1 - 7.1 5.7 7.2 3 6.9 0.6 2.2 1 1 0 2 2 2 0 Cysteine dioxygenase type I V_ATPase_I PF01496.14 KFO97100.1 - 8.3 4.1 18.6 11 3.6 12.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC37_N PF03234.9 KFO97100.1 - 8.5 6.6 25.5 14 5.9 17.7 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding IL7 PF01415.11 KFO97101.1 - 0.0033 17.0 0.5 0.0039 16.8 0.4 1.1 1 0 0 1 1 1 1 Interleukin 7/9 family DUF1741 PF08427.5 KFO97101.1 - 0.075 12.4 0.9 0.076 12.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Enkurin PF13864.1 KFO97101.1 - 0.15 12.2 6.7 0.19 11.9 4.6 1.1 1 0 0 1 1 1 0 Calmodulin-binding CCDC-167 PF15188.1 KFO97101.1 - 7.4 6.5 9.8 96 3.0 6.8 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Mrr_N PF14338.1 KFO97102.1 - 0.025 14.6 0.2 0.047 13.7 0.1 1.5 1 1 0 1 1 1 0 Mrr N-terminal domain UPF0223 PF05256.7 KFO97102.1 - 0.049 13.7 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) DUF1351 PF07083.6 KFO97102.1 - 0.076 12.6 0.1 0.097 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Tropomyosin PF00261.15 KFO97102.1 - 0.096 11.7 0.4 0.13 11.3 0.3 1.2 1 0 0 1 1 1 0 Tropomyosin CCDC144C PF14915.1 KFO97102.1 - 0.15 10.9 2.1 0.18 10.6 1.0 1.4 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region T4_deiodinase PF00837.12 KFO97103.1 - 1.3e-09 37.4 0.2 1.3e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Syndecan PF01034.15 KFO97104.1 - 4.9e-07 29.2 0.8 1.4e-06 27.8 0.5 1.8 1 1 0 1 1 1 1 Syndecan domain CD34_antigen PF06365.7 KFO97104.1 - 0.0046 16.6 0.1 0.0069 16.0 0.1 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF202 PF02656.10 KFO97104.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Laminin_G_2 PF02210.19 KFO97105.1 - 6.8e-16 58.4 0.1 1.1e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFO97105.1 - 1.1e-05 25.4 0.2 1.8e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFO97105.1 - 0.031 14.5 0.2 0.055 13.6 0.1 1.4 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF3439 PF11921.3 KFO97105.1 - 0.24 11.1 5.3 0.39 10.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ABC1 PF03109.11 KFO97107.1 - 1.7e-39 134.5 0.1 2.9e-39 133.7 0.1 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KFO97107.1 - 0.00051 19.8 0.1 0.12 12.0 0.1 2.7 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KFO97107.1 - 0.0011 18.2 0.0 0.0043 16.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain RRM_6 PF14259.1 KFO97108.1 - 2.2e-12 46.7 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO97108.1 - 8.9e-12 44.4 0.0 1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO97108.1 - 2e-08 33.9 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy_2 PF13532.1 KFO97109.1 - 1.3e-38 132.7 0.0 2.3e-38 131.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMOP PF03782.12 KFO97110.1 - 5.8e-43 146.4 1.5 5.8e-43 146.4 1.1 2.0 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.14 KFO97110.1 - 6e-08 32.6 12.2 2.2e-07 30.8 8.5 2.1 1 0 0 1 1 1 1 Thrombospondin type 1 domain Aha1_N PF09229.6 KFO97111.1 - 3.6e-43 146.6 0.5 5.4e-43 146.1 0.4 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFO97111.1 - 6.6e-22 77.9 0.3 1.4e-21 76.8 0.2 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF1005 PF06219.7 KFO97111.1 - 0.059 12.0 0.0 1.1 7.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1005) Golgin_A5 PF09787.4 KFO97112.1 - 1.4e-144 482.4 0.8 1.8e-144 482.0 0.5 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 Vps16_C PF04840.7 KFO97112.1 - 1.3e-12 47.3 3.2 4.8e-06 25.7 0.2 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region GOLD_2 PF13897.1 KFO97114.1 - 6.1e-68 227.2 1.0 6.1e-68 227.2 0.7 1.7 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking Kelch_4 PF13418.1 KFO97115.1 - 6.5e-25 86.6 0.0 4.7e-05 23.0 0.0 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KFO97115.1 - 2.6e-21 75.1 2.3 1.3e-05 25.2 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO97115.1 - 2.4e-15 56.0 0.0 0.0083 16.0 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KFO97115.1 - 5.3e-12 45.3 0.3 0.031 14.4 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KFO97115.1 - 3.5e-11 42.4 0.0 0.019 14.5 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 KFO97115.1 - 8.1e-11 41.2 0.1 0.00027 20.5 0.0 4.1 3 0 0 3 3 3 3 Kelch motif GST_N_3 PF13417.1 KFO97116.1 - 5.2e-17 61.8 0.0 8.3e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFO97116.1 - 1.2e-14 54.2 0.0 2.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFO97116.1 - 5e-14 52.0 0.0 8.9e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFO97116.1 - 6.4e-08 32.4 0.0 9.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFO97116.1 - 0.00016 21.4 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFO97116.1 - 0.0031 17.9 0.0 0.0051 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PMT PF02366.13 KFO97117.1 - 2e-78 263.1 15.1 2e-78 263.1 10.5 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFO97117.1 - 1.7e-26 92.9 0.1 2.3e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 MIR domain Globin PF00042.17 KFO97118.1 - 3.5e-09 36.9 0.0 4.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Globin DUF221 PF02714.10 KFO97119.1 - 2.7e-89 299.2 26.8 2.7e-89 299.2 18.6 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFO97119.1 - 2.5e-25 88.8 1.8 2.5e-25 88.8 1.2 5.2 5 2 0 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFO97119.1 - 3.3e-12 46.7 0.2 6.7e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4131 PF13567.1 KFO97119.1 - 2.9 7.2 24.1 0.17 11.2 0.2 4.5 4 2 0 4 4 4 0 Domain of unknown function (DUF4131) zf-DHHC PF01529.15 KFO97120.1 - 4.4e-18 65.2 9.7 4.4e-18 65.2 6.7 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase InaF-motif PF15018.1 KFO97120.1 - 0.18 11.3 1.9 0.43 10.0 1.3 1.6 1 0 0 1 1 1 0 TRP-interacting helix CoA_binding_3 PF13727.1 KFO97120.1 - 0.19 11.5 1.6 0.39 10.5 1.1 1.6 1 1 0 1 1 1 0 CoA-binding domain Pyocin_S PF06958.7 KFO97121.1 - 0.41 11.0 3.0 0.46 10.8 0.8 2.1 2 1 0 2 2 2 0 S-type Pyocin IRF-2BP1_2 PF11261.3 KFO97122.1 - 4.5e-37 125.2 2.1 4.5e-37 125.2 1.5 1.7 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4 PF00097.20 KFO97122.1 - 0.0012 18.4 7.8 0.0038 16.8 5.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO97122.1 - 0.018 15.0 7.4 0.018 15.0 5.1 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Exo_endo_phos PF03372.18 KFO97124.1 - 1.8e-37 129.6 0.0 2.5e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vasohibin PF14822.1 KFO97125.1 - 2.8e-104 347.5 0.0 3.3e-104 347.3 0.0 1.0 1 0 0 1 1 1 1 Vasohibin Hormone_recep PF00104.25 KFO97127.1 - 6.6e-35 120.0 0.4 1e-34 119.4 0.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO97127.1 - 5.8e-31 106.5 12.3 1.1e-30 105.6 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) IFT43 PF15305.1 KFO97129.1 - 6.4e-47 159.1 1.8 8.4e-47 158.8 1.3 1.1 1 0 0 1 1 1 1 Intraflagellar transport protein 43 TGF_beta PF00019.15 KFO97130.1 - 2.2e-29 101.7 1.0 4e-29 100.9 0.7 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFO97130.1 - 1.4e-21 76.9 0.2 2.2e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TTL PF03133.10 KFO97131.1 - 1.7e-90 302.9 0.0 4.7e-90 301.4 0.0 1.7 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFO97131.1 - 1.7e-07 30.2 0.0 0.0013 17.5 0.0 2.7 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KFO97131.1 - 0.002 17.8 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KFO97131.1 - 0.011 15.1 0.0 0.033 13.6 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Erg28 PF03694.8 KFO97132.1 - 2.8e-09 36.9 5.8 3.6e-09 36.6 4.0 1.1 1 0 0 1 1 1 1 Erg28 like protein NADH5_C PF06455.6 KFO97132.1 - 0.1 11.9 2.5 0.14 11.5 1.6 1.4 1 1 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus MrpF_PhaF PF04066.8 KFO97132.1 - 0.41 10.9 2.6 0.49 10.7 1.4 1.4 1 1 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF2273 PF10031.4 KFO97132.1 - 2.6 7.7 5.3 0.21 11.2 0.4 1.6 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) MFS_1 PF07690.11 KFO97133.1 - 2.7e-27 95.3 50.2 1.1e-24 86.8 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily IncA PF04156.9 KFO97133.1 - 0.51 9.9 0.0 0.51 9.9 0.0 2.4 2 1 0 2 2 2 0 IncA protein UPF0239 PF06783.6 KFO97133.1 - 0.55 10.1 2.1 0.57 10.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) DUF4212 PF13937.1 KFO97133.1 - 6.5 6.8 10.0 0.24 11.3 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) bZIP_1 PF00170.16 KFO97134.1 - 2.2e-11 43.5 8.5 3.2e-11 43.0 5.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFO97134.1 - 1.2e-09 37.8 12.8 1.5e-09 37.5 8.9 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFO97134.1 - 3.8e-07 30.2 9.8 5e-07 29.9 6.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.6 KFO97134.1 - 0.00028 20.1 0.2 0.00032 19.9 0.1 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M SR-25 PF10500.4 KFO97134.1 - 0.00033 20.2 7.5 0.0004 19.9 5.2 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein HALZ PF02183.13 KFO97134.1 - 0.0064 16.1 2.6 0.0064 16.1 1.8 2.2 1 1 1 2 2 2 1 Homeobox associated leucine zipper IncA PF04156.9 KFO97134.1 - 0.016 14.7 6.8 0.021 14.4 4.7 1.1 1 0 0 1 1 1 0 IncA protein BMP2K_C PF15282.1 KFO97134.1 - 0.026 14.6 5.5 0.027 14.6 3.8 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus MAD PF05557.8 KFO97134.1 - 0.027 12.5 6.7 0.034 12.2 4.6 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein AAA_11 PF13086.1 KFO97134.1 - 0.042 13.4 0.7 0.048 13.2 0.5 1.1 1 0 0 1 1 1 0 AAA domain HAP1_N PF04849.8 KFO97134.1 - 0.067 12.1 4.6 0.076 11.9 3.2 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Seryl_tRNA_N PF02403.17 KFO97134.1 - 0.096 12.7 4.7 0.12 12.3 3.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.3 KFO97134.1 - 0.11 11.7 3.1 0.13 11.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 KFO97134.1 - 0.12 11.4 2.8 0.13 11.2 2.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CAF-1_p150 PF11600.3 KFO97134.1 - 0.14 11.5 8.1 0.17 11.2 5.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2681 PF10883.3 KFO97134.1 - 0.75 10.0 5.1 1.7 8.8 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4011 PF13195.1 KFO97134.1 - 0.77 9.7 6.3 1 9.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) TMPIT PF07851.8 KFO97134.1 - 0.77 8.7 2.5 1 8.3 1.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DivIVA PF05103.8 KFO97134.1 - 0.78 9.7 6.9 0.24 11.4 0.4 2.0 1 1 1 2 2 2 0 DivIVA protein DUF904 PF06005.7 KFO97134.1 - 1.1 9.6 6.9 0.2 11.9 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 KFO97134.1 - 2.2 7.8 6.6 5.7 6.4 4.6 1.7 1 1 0 1 1 1 0 Septum formation initiator Vps51 PF08700.6 KFO97134.1 - 4.7 7.1 7.5 40 4.1 5.2 2.0 1 1 0 1 1 1 0 Vps51/Vps67 bZIP_1 PF00170.16 KFO97135.1 - 1.2e-10 41.1 21.7 2e-10 40.4 15.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFO97135.1 - 5.8e-09 35.6 22.3 9.7e-09 34.9 15.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFO97135.1 - 3.4e-08 33.6 12.0 5.3e-08 33.0 8.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.4 KFO97135.1 - 0.042 12.1 8.9 0.052 11.8 6.1 1.0 1 0 0 1 1 1 0 Transmembrane protein UPF0542 PF15086.1 KFO97135.1 - 0.18 11.5 2.0 0.36 10.5 1.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 V_ATPase_I PF01496.14 KFO97135.1 - 0.27 9.0 3.4 0.31 8.8 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KFO97135.1 - 0.29 9.5 2.5 0.32 9.3 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2868 PF11067.3 KFO97135.1 - 0.33 10.0 1.5 0.39 9.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Atg14 PF10186.4 KFO97135.1 - 0.35 9.7 10.1 0.52 9.1 7.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KFO97135.1 - 0.82 8.6 6.9 0.9 8.5 4.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFO97135.1 - 2.1 7.8 9.5 3.9 7.0 6.6 1.4 1 0 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 KFO97136.1 - 1.2e-37 129.3 0.1 1.4e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Flag1_repress PF03614.8 KFO97136.1 - 0.043 13.3 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Pkinase PF00069.20 KFO97137.1 - 1.1e-52 178.8 0.1 1.6e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.13 KFO97137.1 - 1.2e-47 159.9 22.7 1.5e-13 50.7 0.1 8.1 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFO97137.1 - 2.9e-34 115.9 16.2 2e-07 30.4 0.2 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.12 KFO97137.1 - 8.9e-34 116.7 1.2 9.6e-34 116.6 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO97137.1 - 0.00069 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-C2HC_2 PF13913.1 KFO97138.1 - 5.4e-17 60.9 9.0 1.1e-08 34.5 1.1 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type FYVE PF01363.16 KFO97138.1 - 0.0019 18.0 1.9 0.1 12.5 0.1 2.2 2 0 0 2 2 2 1 FYVE zinc finger zf-CHCC PF10276.4 KFO97138.1 - 0.0042 16.9 2.4 0.25 11.1 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger domain Nairovirus_M PF07948.6 KFO97138.1 - 0.026 12.6 0.8 0.026 12.6 0.5 1.6 2 0 0 2 2 2 0 Nairovirus M polyprotein-like Sgf11 PF08209.6 KFO97138.1 - 0.038 13.2 9.5 0.06 12.6 0.8 2.5 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 KFO97138.1 - 0.053 13.8 5.8 3 8.3 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_3 PF14369.1 KFO97138.1 - 0.062 13.3 2.4 0.37 10.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger zf-C2H2 PF00096.21 KFO97138.1 - 0.096 13.0 7.7 5.9 7.4 2.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 KFO97138.1 - 0.33 11.0 6.5 4.9 7.3 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.14 KFO97138.1 - 0.71 9.5 2.7 11 5.6 0.1 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF3039 PF11238.3 KFO97138.1 - 1.3 8.5 5.6 1.3 8.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) zf-C2H2_4 PF13894.1 KFO97138.1 - 2.5 8.6 10.8 8 7.0 2.2 3.1 3 1 0 3 3 2 0 C2H2-type zinc finger Acylphosphatase PF00708.13 KFO97139.1 - 3.5e-25 87.9 0.7 3.8e-25 87.8 0.5 1.0 1 0 0 1 1 1 1 Acylphosphatase MutL_C PF08676.6 KFO97140.1 - 2.4e-13 49.9 0.4 1.5e-12 47.2 0.3 2.3 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KFO97140.1 - 9.5e-12 44.4 0.0 1.7e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KFO97140.1 - 9.8e-11 41.3 0.2 4.3e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFO97140.1 - 5e-10 39.1 0.2 1.3e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IF-2B PF01008.12 KFO97141.1 - 2.3e-81 272.9 0.1 2.6e-81 272.7 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PDGF PF00341.12 KFO97142.1 - 1.6e-26 92.2 5.7 1.9e-26 92.0 4.0 1.0 1 0 0 1 1 1 1 PDGF/VEGF domain Pkinase PF00069.20 KFO97143.1 - 1.3e-20 73.6 0.0 2.7e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97143.1 - 9.7e-13 47.7 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.13 KFO97143.1 - 0.0027 17.5 0.4 0.0047 16.7 0.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Kinase-like PF14531.1 KFO97143.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFO97143.1 - 0.045 13.4 0.1 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family 2-oxoacid_dh PF00198.18 KFO97144.1 - 6.7e-80 267.6 0.2 8.3e-80 267.3 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFO97144.1 - 3.4e-21 74.6 0.6 5.8e-21 73.9 0.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KFO97144.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like GCV_H PF01597.14 KFO97144.1 - 0.023 14.3 0.8 0.059 13.0 0.5 1.6 1 1 1 2 2 2 0 Glycine cleavage H-protein HlyD_2 PF12700.2 KFO97144.1 - 0.041 13.0 0.1 4.5 6.3 0.0 2.8 2 1 1 3 3 3 0 HlyD family secretion protein HlyD PF00529.15 KFO97144.1 - 0.051 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein HpaP PF09483.5 KFO97144.1 - 2.7 7.8 16.7 4.7 7.1 11.5 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) PAT1 PF09770.4 KFO97144.1 - 5.2 5.1 6.2 6.4 4.8 4.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fcf1 PF04900.7 KFO97145.1 - 3.5e-41 139.4 1.6 4.8e-41 138.9 1.1 1.2 1 0 0 1 1 1 1 Fcf1 HECT PF00632.20 KFO97146.1 - 7.5e-81 271.7 0.1 1.1e-80 271.1 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.14 KFO97146.1 - 3.5e-10 40.3 0.3 1.8e-06 28.4 0.0 3.3 3 0 0 3 3 3 2 Filamin/ABP280 repeat DUF4432 PF14486.1 KFO97146.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) EGF_CA PF07645.10 KFO97147.1 - 3.2e-106 347.1 267.0 2.6e-09 36.9 3.9 20.1 20 0 0 20 20 20 16 Calcium-binding EGF domain cEGF PF12662.2 KFO97147.1 - 3.6e-71 234.2 158.2 6.7e-09 35.2 2.4 19.8 18 0 0 18 18 18 17 Complement Clr-like EGF-like TB PF00683.12 KFO97147.1 - 3.3e-47 157.7 40.8 4.7e-16 58.0 3.5 5.6 4 0 0 4 4 4 4 TB domain EGF PF00008.22 KFO97147.1 - 1.8e-42 142.8 254.6 0.00057 19.7 3.5 22.9 21 1 2 23 23 23 17 EGF-like domain FXa_inhibition PF14670.1 KFO97147.1 - 6.2e-19 67.8 272.1 5.5e-05 23.1 5.1 21.4 17 3 4 21 21 21 15 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFO97147.1 - 5.1e-17 61.5 202.1 0.00043 20.1 1.0 19.9 19 0 0 19 19 19 15 EGF domain EGF_2 PF07974.8 KFO97147.1 - 0.0076 16.3 10.1 0.0076 16.3 7.0 21.5 20 2 2 22 22 22 6 EGF-like domain E1_DerP2_DerF2 PF02221.10 KFO97148.1 - 4e-31 108.0 0.5 4.5e-31 107.8 0.3 1.0 1 0 0 1 1 1 1 ML domain Fe-S_biosyn PF01521.15 KFO97149.1 - 5.4e-12 45.6 0.0 7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Dispanin PF04505.7 KFO97150.1 - 6e-23 80.1 0.0 9.6e-23 79.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein HTH_Tnp_1 PF01527.15 KFO97151.1 - 1.3e-07 31.4 10.0 0.0033 17.3 0.0 4.6 5 0 0 5 5 5 3 Transposase HTH_28 PF13518.1 KFO97151.1 - 4.6e-06 26.5 6.1 0.89 9.6 0.1 4.8 5 0 0 5 5 5 2 Helix-turn-helix domain HTH_23 PF13384.1 KFO97151.1 - 8.6e-06 25.2 1.7 0.57 9.9 0.0 4.3 4 0 0 4 4 4 2 Homeodomain-like domain DUF1492 PF07374.6 KFO97151.1 - 0.0022 18.0 6.7 1.3 9.1 0.0 4.3 5 0 0 5 5 5 2 Protein of unknown function (DUF1492) OTU PF02338.14 KFO97151.1 - 0.0087 16.6 0.0 0.023 15.3 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease HTH_Tnp_1_2 PF13022.1 KFO97151.1 - 0.037 13.8 0.3 6 6.6 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase HTH_26 PF13443.1 KFO97151.1 - 0.18 12.0 0.1 14 5.9 0.0 3.7 5 0 0 5 5 5 0 Cro/C1-type HTH DNA-binding domain ABC_membrane_2 PF06472.10 KFO97152.1 - 3.1e-82 275.9 2.7 4e-82 275.5 1.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFO97152.1 - 3.4e-17 63.0 0.0 5.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KFO97152.1 - 0.00053 20.0 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SbmA_BacA PF05992.7 KFO97152.1 - 0.0018 17.5 3.1 0.0033 16.6 2.1 1.4 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_30 PF13604.1 KFO97152.1 - 0.0076 15.8 0.0 0.044 13.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KFO97152.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFO97152.1 - 0.027 14.8 0.4 0.046 14.0 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFO97152.1 - 0.038 14.1 0.4 0.18 11.9 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFO97152.1 - 0.046 13.2 0.2 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 KFO97152.1 - 0.051 13.0 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Miro PF08477.8 KFO97152.1 - 0.072 13.5 0.2 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 KFO97152.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 KFO97152.1 - 0.1 11.7 0.4 0.17 11.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 KFO97152.1 - 0.11 12.2 0.1 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KFO97152.1 - 0.14 11.6 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 KFO97152.1 - 0.14 11.0 0.3 0.24 10.2 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KFO97152.1 - 0.18 11.2 0.9 0.75 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AMP-binding_C PF13193.1 KFO97153.1 - 1.4e-18 67.6 0.3 2e-18 67.0 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KFO97153.1 - 4.8e-10 38.4 0.0 5.9e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 KFO97154.1 - 8.7e-21 73.7 0.0 9.6e-21 73.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF1967 PF09269.6 KFO97154.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Homeobox PF00046.24 KFO97155.1 - 4.8e-23 80.5 1.5 6.2e-23 80.1 1.0 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO97155.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain Ret_tiss PF10044.4 KFO97156.1 - 2.1e-23 82.6 0.0 2.2e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Retinal tissue protein Aldedh PF00171.17 KFO97157.1 - 8.8e-120 400.1 0.0 9.9e-120 399.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFO97157.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF4515 PF14988.1 KFO97158.1 - 3.8e-07 30.0 19.8 3.8e-07 30.0 13.7 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4515) AHS1 PF02682.11 KFO97158.1 - 0.45 9.9 3.6 0.85 9.0 0.9 2.2 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 GDA1_CD39 PF01150.12 KFO97159.1 - 4.9e-76 255.9 0.0 3.7e-75 253.0 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family FAD_binding_3 PF01494.14 KFO97160.1 - 5.4e-17 61.8 0.3 1.9e-10 40.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 KFO97160.1 - 0.00049 19.0 0.0 0.00091 18.1 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.9 KFO97160.1 - 0.012 14.2 0.0 0.83 8.2 0.0 2.2 2 1 0 2 2 2 0 Tryptophan halogenase UPF0564 PF10595.4 KFO97161.1 - 1.3e-77 261.1 42.4 2e-77 260.5 29.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 BCS1_N PF08740.6 KFO97161.1 - 0.043 13.4 9.5 0.047 13.2 0.7 2.7 3 0 0 3 3 3 0 BCS1 N terminal zf-H2C2_2 PF13465.1 KFO97162.1 - 2.5e-29 100.0 29.1 1.3e-07 31.5 0.2 6.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFO97162.1 - 3.3e-23 80.5 26.3 5e-05 23.3 0.1 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97162.1 - 2e-15 55.9 24.6 0.0001 22.4 1.9 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFO97162.1 - 1.5e-05 24.5 4.2 0.37 10.4 0.0 4.8 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFO97162.1 - 0.0023 17.9 10.3 0.49 10.6 0.0 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO97162.1 - 0.0047 17.0 9.9 0.61 10.3 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type CHORD PF04968.7 KFO97162.1 - 0.13 12.5 12.5 1.7 8.9 0.0 4.7 2 1 3 5 5 5 0 CHORD zf-C2H2_2 PF12756.2 KFO97162.1 - 0.51 10.4 9.9 0.23 11.5 0.5 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFO97162.1 - 8.3 6.4 17.6 0.37 10.7 0.3 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger Pinin_SDK_N PF04697.8 KFO97164.1 - 3.4e-72 240.7 9.6 3.4e-72 240.7 6.7 3.9 4 1 0 4 4 4 1 pinin/SDK conserved region Pinin_SDK_memA PF04696.8 KFO97164.1 - 6.5e-50 168.1 18.3 6.5e-50 168.1 12.7 4.9 4 2 2 6 6 6 1 pinin/SDK/memA/ protein conserved region TRAPP PF04051.11 KFO97165.1 - 2.3e-36 124.6 0.2 2.5e-36 124.5 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SIP1 PF04938.7 KFO97166.1 - 9.8e-107 355.6 0.3 1.1e-106 355.4 0.2 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Sec23_trunk PF04811.10 KFO97167.1 - 2.1e-81 272.8 0.0 2.9e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFO97167.1 - 5.9e-35 118.8 0.1 1.2e-34 117.8 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFO97167.1 - 3.7e-33 113.9 0.0 8.1e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFO97167.1 - 4.6e-15 54.8 6.4 8.6e-15 54.0 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFO97167.1 - 9.4e-15 54.0 0.0 2.5e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat APP_E2 PF12925.2 KFO97167.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein AphA_like PF14557.1 KFO97167.1 - 0.2 11.1 0.2 0.36 10.3 0.2 1.3 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator 7tm_1 PF00001.16 KFO97168.1 - 2.9e-69 233.0 28.2 3.8e-69 232.6 19.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97168.1 - 3.1e-14 52.7 24.1 3.8e-14 52.4 16.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFO97168.1 - 6.9e-09 35.2 14.9 6.9e-09 35.2 10.3 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFO97168.1 - 2.3e-06 26.9 22.8 4e-06 26.1 15.1 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx T2SM PF04612.7 KFO97168.1 - 0.019 14.7 0.8 0.019 14.7 0.5 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4131 PF13567.1 KFO97168.1 - 1.6 8.1 4.4 8.5 5.7 1.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) COX7C PF02935.11 KFO97168.1 - 2.6 7.8 6.1 0.45 10.3 0.2 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc 60KD_IMP PF02096.15 KFO97168.1 - 6 6.4 13.5 20 4.7 9.4 2.0 1 1 0 1 1 1 0 60Kd inner membrane protein TPR_11 PF13414.1 KFO97169.1 - 5.7e-84 275.7 39.8 2e-12 46.5 0.0 10.2 5 3 4 10 10 10 10 TPR repeat TPR_1 PF00515.23 KFO97169.1 - 2.3e-58 191.5 56.6 2.4e-06 26.9 0.2 17.5 17 2 1 18 18 18 14 Tetratricopeptide repeat TPR_2 PF07719.12 KFO97169.1 - 7.9e-52 169.0 41.7 3.3e-05 23.4 0.0 17.9 17 3 1 18 18 18 13 Tetratricopeptide repeat TPR_9 PF13371.1 KFO97169.1 - 3.2e-32 110.2 2.3 4e-05 23.3 0.0 9.1 2 2 8 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97169.1 - 2.5e-31 107.6 2.3 9e-05 23.0 0.0 11.7 3 3 11 14 14 14 7 Tetratricopeptide repeat TPR_17 PF13431.1 KFO97169.1 - 1.1e-30 103.2 31.3 0.0071 16.4 0.1 12.7 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_8 PF13181.1 KFO97169.1 - 5.1e-27 91.6 38.3 0.0017 17.9 0.0 14.6 13 1 2 15 15 15 8 Tetratricopeptide repeat TPR_12 PF13424.1 KFO97169.1 - 2.1e-24 85.2 29.9 0.00017 21.4 0.0 11.2 4 2 7 13 13 13 8 Tetratricopeptide repeat TPR_14 PF13428.1 KFO97169.1 - 1.2e-20 72.0 6.2 0.18 12.5 0.0 12.3 5 4 11 16 16 16 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97169.1 - 4e-20 71.9 12.9 1.2e-06 28.6 0.0 8.3 6 1 3 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 KFO97169.1 - 1e-12 47.9 40.9 6.6e-05 22.9 3.0 7.6 3 3 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFO97169.1 - 6e-11 41.2 9.9 4.5 7.3 0.0 10.5 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO97169.1 - 5.2e-07 29.6 27.9 0.92 10.1 0.1 11.5 14 1 0 14 14 11 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFO97169.1 - 4.1e-05 23.3 11.5 0.098 12.5 0.0 6.0 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 KFO97169.1 - 0.049 12.8 14.1 0.29 10.4 0.0 7.9 11 0 0 11 11 11 0 SHNi-TPR TPR_21 PF09976.4 KFO97169.1 - 2.8 7.8 9.8 88 3.0 0.1 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Fork_head PF00250.13 KFO97170.1 - 5.8e-47 157.6 0.4 1.2e-46 156.6 0.3 1.6 1 0 0 1 1 1 1 Fork head domain Fork_head_N PF08430.7 KFO97170.1 - 2.4e-25 89.5 30.7 2.4e-25 89.5 21.3 3.1 2 1 1 3 3 3 1 Forkhead N-terminal region HNF_C PF09354.5 KFO97170.1 - 7e-19 68.7 3.0 7e-19 68.7 2.1 4.2 4 2 1 5 5 5 1 HNF3 C-terminal domain FUSC PF04632.7 KFO97171.1 - 9.2 4.5 11.1 0.45 8.8 3.7 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family Mito_carr PF00153.22 KFO97172.1 - 5.4e-54 179.8 1.6 1.1e-20 73.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PAX PF00292.13 KFO97173.1 - 5.2e-71 236.2 0.2 8.3e-71 235.5 0.2 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 KFO97173.1 - 2.5e-07 30.0 0.1 6.9e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 KFO97173.1 - 0.0024 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KFO97173.1 - 0.041 14.6 0.0 0.1 13.4 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFO97174.1 - 5e-21 74.0 4.6 8.9e-21 73.2 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain Adhesin_P1 PF03257.8 KFO97174.1 - 4.5 7.6 11.3 1.6 9.0 5.3 2.2 2 0 0 2 2 2 0 Mycoplasma adhesin P1 TruD PF01142.13 KFO97175.1 - 0.0023 16.6 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Sdh5 PF03937.11 KFO97175.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Sds3 PF08598.6 KFO97176.1 - 1.2e-45 155.6 8.7 2.3e-45 154.6 6.0 1.5 1 1 0 1 1 1 1 Sds3-like ING PF12998.2 KFO97176.1 - 0.035 14.3 3.8 0.26 11.5 2.6 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Borrelia_P83 PF05262.6 KFO97176.1 - 0.17 10.0 5.7 0.24 9.6 3.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AATF-Che1 PF13339.1 KFO97176.1 - 0.46 10.6 5.1 0.33 11.1 0.2 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF16 PF01519.11 KFO97176.1 - 1.2 9.3 5.8 3.9 7.7 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Ank PF00023.25 KFO97177.1 - 5.1e-37 123.8 7.9 3.1e-10 39.3 0.2 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 KFO97177.1 - 5.8e-33 113.0 2.4 4.2e-17 62.2 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFO97177.1 - 2.5e-27 92.2 4.4 1.6e-06 27.7 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFO97177.1 - 1.1e-26 92.2 3.3 3.1e-10 39.9 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO97177.1 - 1.6e-23 82.6 3.6 6.7e-11 42.3 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFO97177.1 - 0.0034 16.9 0.0 0.007 15.9 0.0 1.5 2 0 0 2 2 2 1 Shigella flexneri OspC protein DUF3571 PF12095.3 KFO97177.1 - 0.05 13.8 0.2 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) Proteasome PF00227.21 KFO97178.1 - 5.8e-53 179.0 0.2 6.7e-53 178.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit PPR_2 PF13041.1 KFO97179.1 - 5.6e-08 32.6 3.6 0.048 13.6 0.0 4.1 3 1 1 4 4 4 2 PPR repeat family RNase_Zc3h12a PF11977.3 KFO97179.1 - 1e-06 28.6 0.1 3.4e-06 26.9 0.1 1.9 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_3 PF13812.1 KFO97179.1 - 6.2e-06 26.0 0.2 0.29 11.5 0.0 3.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 KFO97179.1 - 0.00022 20.9 12.7 0.01 15.7 0.1 4.6 5 0 0 5 5 5 2 PPR repeat Rad50_zn_hook PF04423.9 KFO97179.1 - 0.0034 16.8 0.2 0.086 12.3 0.0 2.7 2 0 0 2 2 2 1 Rad50 zinc hook motif EF-hand_7 PF13499.1 KFO97180.1 - 6.4e-11 42.2 5.7 0.0014 18.7 0.1 4.7 3 2 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.1 KFO97180.1 - 1e-05 25.0 4.3 1.3 9.0 0.0 5.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KFO97180.1 - 4.8e-05 22.3 0.1 0.19 11.0 0.0 3.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFO97180.1 - 0.0018 17.8 0.1 2.5 7.7 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFO97180.1 - 0.028 13.7 0.2 0.24 10.8 0.0 2.7 2 0 0 2 2 2 0 EF hand FAM177 PF14774.1 KFO97181.1 - 8.3e-30 103.2 0.0 8.3e-30 103.2 0.0 1.9 1 1 1 2 2 2 1 FAM177 family MCPVI PF02993.9 KFO97181.1 - 0.056 13.6 0.4 0.064 13.4 0.3 1.0 1 0 0 1 1 1 0 Minor capsid protein VI DUF904 PF06005.7 KFO97181.1 - 0.066 13.5 5.7 0.094 13.0 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) LLC1 PF14945.1 KFO97181.1 - 0.18 12.1 3.5 0.24 11.7 2.4 1.1 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF2215 PF10225.4 KFO97181.1 - 0.24 10.8 0.6 0.25 10.7 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) SRP54 PF00448.17 KFO97182.1 - 1.1e-77 259.9 0.6 8e-77 257.1 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KFO97182.1 - 1.2e-26 93.0 3.3 1.2e-26 93.0 2.3 3.8 2 1 2 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.14 KFO97182.1 - 1.9e-17 63.0 2.8 5.2e-17 61.7 1.9 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KFO97182.1 - 1.4e-07 31.1 0.6 6.1e-07 29.0 0.2 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFO97182.1 - 1.3e-06 28.3 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KFO97182.1 - 7.8e-06 25.6 0.0 2.7e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2209 PF09974.4 KFO97182.1 - 1.6e-05 24.9 0.2 4.8e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) CbiA PF01656.18 KFO97182.1 - 2.5e-05 23.7 0.0 0.0001 21.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.5 KFO97182.1 - 2.9e-05 23.3 0.6 0.072 12.2 0.0 2.7 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit AAA_31 PF13614.1 KFO97182.1 - 0.00017 21.5 0.1 0.4 10.6 0.0 3.4 3 1 1 4 4 3 1 AAA domain AAA_17 PF13207.1 KFO97182.1 - 0.00024 21.8 0.0 0.00086 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFO97182.1 - 0.0016 18.5 0.5 0.0083 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 KFO97182.1 - 0.0018 17.1 0.0 0.032 13.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 KFO97182.1 - 0.0027 17.6 0.4 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KFO97182.1 - 0.0029 17.1 0.0 0.0042 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 KFO97182.1 - 0.0039 16.8 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFO97182.1 - 0.0075 15.8 0.0 0.025 14.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KFO97182.1 - 0.015 15.6 0.1 0.06 13.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KFO97182.1 - 0.024 14.1 1.1 0.17 11.4 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.15 KFO97182.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.13 KFO97182.1 - 0.03 13.3 0.0 0.073 12.1 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.1 KFO97182.1 - 0.037 14.0 0.0 0.12 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KFO97182.1 - 0.041 12.9 0.0 0.087 11.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KFO97182.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFO97182.1 - 0.18 12.1 1.3 2 8.6 0.9 2.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFO97182.1 - 0.3 11.3 4.3 0.5 10.5 0.1 3.2 3 2 1 4 4 2 0 ATPase family associated with various cellular activities (AAA) Methyltransf_26 PF13659.1 KFO97183.1 - 8.5e-08 32.2 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO97183.1 - 1.6e-05 25.4 0.0 3.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO97183.1 - 5.6e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO97183.1 - 5.8e-05 23.4 0.4 0.00026 21.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO97183.1 - 0.00033 20.4 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO97183.1 - 0.00043 20.5 0.2 0.001 19.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KFO97183.1 - 0.00058 19.1 0.1 0.00089 18.5 0.1 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain DOT1 PF08123.8 KFO97183.1 - 0.016 14.4 1.2 0.2 10.9 0.8 2.4 1 1 0 1 1 1 0 Histone methylation protein DOT1 Met_10 PF02475.11 KFO97183.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein NTP_transf_3 PF12804.2 KFO97183.1 - 0.14 12.2 0.0 1 9.4 0.0 2.0 2 0 0 2 2 2 0 MobA-like NTP transferase domain WAC_Acf1_DNA_bd PF10537.4 KFO97184.1 - 7.9e-27 93.4 0.0 7.9e-27 93.4 0.0 4.0 4 0 0 4 4 4 1 ATP-utilising chromatin assembly and remodelling N-terminal Bromodomain PF00439.20 KFO97184.1 - 3.6e-21 74.8 0.3 7.6e-21 73.8 0.2 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 KFO97184.1 - 3.5e-14 52.2 5.8 8e-14 51.0 4.0 1.7 1 0 0 1 1 1 1 PHD-finger DDT PF02791.12 KFO97184.1 - 1e-09 38.0 3.6 2e-09 37.0 1.0 2.4 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.1 KFO97184.1 - 9.6e-05 22.1 0.0 0.00041 20.1 0.0 2.2 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KFO97184.1 - 0.00028 20.6 0.1 0.00074 19.3 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Prok-RING_1 PF14446.1 KFO97184.1 - 0.0028 17.3 2.6 0.0067 16.1 1.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 KFO97184.1 - 0.041 14.0 1.8 0.2 11.8 1.3 2.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.1 KFO97184.1 - 1.1 9.1 5.1 2.3 8.1 3.5 1.6 1 0 0 1 1 1 0 Ring finger domain Tnp_zf-ribbon_2 PF13842.1 KFO97184.1 - 7.1 7.1 9.4 0.42 11.0 2.3 2.2 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Cofilin_ADF PF00241.15 KFO97185.1 - 4.4e-38 130.0 0.5 5.3e-38 129.7 0.4 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PX PF00787.19 KFO97186.1 - 2.1e-18 66.1 0.6 2.4e-14 53.0 0.1 3.2 2 1 1 3 3 3 2 PX domain Vps5 PF09325.5 KFO97186.1 - 1.4e-16 60.4 15.3 1.9e-14 53.5 8.1 2.9 2 1 0 2 2 2 1 Vps5 C terminal like BAR PF03114.13 KFO97186.1 - 1.6e-08 34.3 13.7 8.2e-06 25.4 6.0 2.9 3 0 0 3 3 3 2 BAR domain DUF2419 PF10343.4 KFO97186.1 - 0.015 14.5 1.1 0.024 13.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2419) DUF1825 PF08855.5 KFO97186.1 - 0.064 13.2 2.4 0.09 12.7 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) Eapp_C PF10238.4 KFO97187.1 - 1.9e-50 170.2 9.2 3e-50 169.6 6.4 1.3 1 0 0 1 1 1 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 KFO97187.1 - 0.0079 16.2 6.3 0.016 15.2 4.3 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_4 PF07975.7 KFO97187.1 - 0.013 15.4 3.0 0.037 14.0 0.2 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain DUF2489 PF10675.4 KFO97187.1 - 0.047 13.3 0.2 0.047 13.3 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) IBR PF01485.16 KFO97187.1 - 0.08 12.8 0.3 0.08 12.8 0.2 2.3 2 1 0 2 2 2 0 IBR domain DUF3317 PF11779.3 KFO97188.1 - 1.7e-06 27.3 0.2 1.9e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) COX14 PF14880.1 KFO97188.1 - 0.11 12.1 1.2 0.11 12.0 0.9 1.0 1 0 0 1 1 1 0 Cytochrome oxidase c assembly 2OG-FeII_Oxy_3 PF13640.1 KFO97189.1 - 6.1e-13 49.1 0.0 6.7e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFO97189.1 - 4.6e-06 26.8 0.0 4.8e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFO97189.1 - 3.4e-05 23.3 0.1 8.3e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PAS_3 PF08447.6 KFO97190.1 - 3.3e-17 62.3 0.1 4.6e-16 58.7 0.1 2.3 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 KFO97190.1 - 4.3e-12 45.9 0.0 1.6e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 KFO97190.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KFO97190.1 - 0.0027 17.4 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold Kazal_2 PF07648.10 KFO97192.1 - 3.2e-17 62.1 17.4 1.6e-10 40.7 3.9 4.1 5 0 0 5 5 5 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFO97192.1 - 3e-14 52.7 25.8 1e-09 38.2 4.5 4.6 3 3 1 4 4 4 2 Kazal-type serine protease inhibitor domain hEGF PF12661.2 KFO97192.1 - 0.0011 18.9 3.4 0.0011 18.9 2.3 4.4 4 0 0 4 4 4 1 Human growth factor-like EGF Serglycin PF04360.7 KFO97192.1 - 0.053 13.2 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Serglycin EphA2_TM PF14575.1 KFO97192.1 - 0.075 13.4 1.6 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 KFO97194.1 - 2.8e-56 190.5 0.0 3.2e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97194.1 - 4.5e-35 120.9 0.0 5.3e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO97194.1 - 1.6e-09 37.1 0.0 2.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO97194.1 - 0.00025 20.2 0.1 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFO97194.1 - 0.043 13.1 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KFO97194.1 - 0.063 12.9 0.3 0.18 11.5 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFO97194.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myosin_head PF00063.16 KFO97195.1 - 1.2e-254 846.5 2.3 1.8e-254 846.0 1.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFO97195.1 - 2.4e-47 160.8 2.0 2.4e-47 160.8 1.4 2.2 2 0 0 2 2 2 1 Myosin tail IQ PF00612.22 KFO97195.1 - 0.00074 18.9 0.5 0.00074 18.9 0.4 6.3 6 0 0 6 6 6 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.7 KFO97195.1 - 0.032 13.5 1.0 1.1 8.5 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 KFO97195.1 - 0.034 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFO97195.1 - 0.05 13.0 0.0 0.89 9.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 KFO97195.1 - 0.052 14.3 2.2 0.16 12.8 0.0 3.1 4 0 0 4 4 4 0 AAA domain Frizzled PF01534.12 KFO97196.1 - 5.5e-120 400.0 13.5 6.3e-120 399.8 9.3 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 KFO97196.1 - 1.4e-05 24.1 2.8 1.4e-05 24.1 2.0 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DUF4131 PF13567.1 KFO97196.1 - 5.3 6.4 11.8 5.2 6.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) rve PF00665.21 KFO97197.1 - 1.2e-21 76.9 0.1 4e-20 72.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RNase_H PF00075.19 KFO97197.1 - 5.5e-11 42.9 0.0 9.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 RNase H Integrase_Zn PF02022.14 KFO97197.1 - 1.8e-10 40.0 0.3 4.1e-10 38.9 0.2 1.6 1 0 0 1 1 1 1 Integrase Zinc binding domain zf-C2H2 PF00096.21 KFO97198.1 - 1.8e-05 24.7 13.7 0.0001 22.4 1.3 2.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO97198.1 - 3.7e-05 23.8 13.1 4e-05 23.6 2.0 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO97198.1 - 5.5e-05 23.2 2.7 5.5e-05 23.2 1.9 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFO97198.1 - 0.00028 20.4 0.3 0.00068 19.2 0.2 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 KFO97198.1 - 0.00049 19.9 2.5 0.13 12.2 0.2 2.1 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFO97198.1 - 0.0018 18.3 1.2 0.0018 18.3 0.9 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO97198.1 - 0.0048 16.7 0.7 0.0048 16.7 0.5 2.2 2 1 0 2 2 2 1 C2H2-type zinc finger Evr1_Alr PF04777.8 KFO97198.1 - 0.014 15.2 0.5 0.015 15.2 0.3 1.2 1 0 0 1 1 1 0 Erv1 / Alr family zf-met PF12874.2 KFO97198.1 - 0.45 10.7 4.7 0.56 10.4 1.3 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TRAPPC9-Trs120 PF08626.6 KFO97203.1 - 5.7e-08 30.6 0.0 6.3e-08 30.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ion_trans_2 PF07885.11 KFO97204.1 - 2.2e-36 123.3 17.0 2.3e-19 68.8 0.2 2.9 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 KFO97204.1 - 0.00013 21.2 9.7 0.023 13.9 0.1 2.5 1 1 1 2 2 2 2 Ion transport protein CytochromB561_N PF09786.4 KFO97204.1 - 0.0036 15.8 0.1 0.0054 15.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal IRK PF01007.15 KFO97204.1 - 0.17 10.6 2.0 0.36 9.5 0.0 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel DUF676 PF05057.9 KFO97206.1 - 1.1e-57 194.8 0.0 1.8e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 KFO97206.1 - 5.9e-26 90.3 11.1 2.9e-17 62.5 0.8 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3657) PGAP1 PF07819.8 KFO97206.1 - 1.3e-05 24.9 0.0 3.6e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.10 KFO97206.1 - 0.00055 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase KH_1 PF00013.24 KFO97208.1 - 0.00089 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFO97208.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-H2C2_2 PF13465.1 KFO97210.1 - 2.9e-45 150.3 138.6 1.3e-07 31.5 0.1 21.4 22 1 0 22 22 22 14 Zinc-finger double domain zf-C2H2 PF00096.21 KFO97210.1 - 1e-37 126.1 157.8 0.00017 21.7 2.3 19.4 19 0 0 19 19 19 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97210.1 - 4.2e-36 120.6 140.4 0.0014 18.8 0.3 19.4 19 0 0 19 19 19 18 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFO97210.1 - 1.6e-21 75.1 123.1 0.0021 18.1 0.4 16.6 16 0 0 16 16 16 10 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KFO97210.1 - 2.9e-13 49.7 97.5 0.0037 17.3 0.2 12.6 9 3 5 14 14 14 9 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFO97210.1 - 8.9e-05 22.5 5.5 8.9e-05 22.5 3.8 15.0 4 2 10 15 15 15 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFO97210.1 - 0.013 15.7 0.3 0.013 15.7 0.2 15.0 16 0 0 16 16 16 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO97210.1 - 0.035 14.2 0.5 0.035 14.2 0.3 16.0 19 0 0 19 19 19 0 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.9 KFO97210.1 - 1.2 8.6 16.0 0.28 10.7 0.1 4.9 6 0 0 6 6 6 0 Rad50 zinc hook motif RVT_1 PF00078.22 KFO97211.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_29 PF00777.13 KFO97214.1 - 8.6e-84 280.8 0.0 9.5e-84 280.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) G_glu_transpept PF01019.16 KFO97214.1 - 0.03 12.8 0.0 0.04 12.4 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Ndr PF03096.9 KFO97215.1 - 5.9e-125 415.4 0.0 7e-125 415.1 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 KFO97215.1 - 6.1e-16 58.9 0.0 8.3e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO97215.1 - 2.9e-05 23.7 0.0 0.0002 20.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFO97215.1 - 0.00093 18.9 0.0 0.0022 17.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family IGFBP PF00219.13 KFO97216.1 - 1.4e-14 54.3 21.5 1.4e-14 54.3 14.9 5.7 5 3 0 5 5 5 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 KFO97216.1 - 8.4e-10 38.6 3.8 8.4e-10 38.6 2.6 3.7 4 0 0 4 4 4 1 Thrombospondin type 1 domain Cys_knot PF00007.17 KFO97216.1 - 1.9e-08 34.3 7.6 1.9e-08 34.3 5.3 4.3 4 2 1 5 5 5 1 Cystine-knot domain VWC PF00093.13 KFO97216.1 - 1.9e-08 34.2 12.0 1.9e-08 34.2 8.3 5.3 4 3 0 4 4 4 1 von Willebrand factor type C domain SH2 PF00017.19 KFO97217.1 - 5.1e-21 74.2 0.5 1.3e-20 72.9 0.1 1.8 2 0 0 2 2 2 1 SH2 domain SH3_9 PF14604.1 KFO97217.1 - 1.4e-08 34.2 0.1 2.6e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFO97217.1 - 3.4e-07 29.5 0.0 6.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFO97217.1 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain KCNQ_channel PF03520.9 KFO97219.1 - 1.5e-55 187.7 0.1 2.9e-55 186.7 0.1 1.5 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.3 KFO97219.1 - 1.1e-45 153.7 4.5 1.9e-45 153.0 1.5 2.2 2 0 0 2 2 2 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.26 KFO97219.1 - 1e-23 83.6 1.0 1.8e-23 82.8 0.7 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFO97219.1 - 2.2e-12 46.4 0.5 5.4e-12 45.2 0.3 1.6 1 0 0 1 1 1 1 Ion channel Lig_chan PF00060.21 KFO97219.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Phospholip_A2_1 PF00068.14 KFO97221.1 - 2.2e-43 147.1 38.0 1.1e-22 80.4 10.5 2.2 2 0 0 2 2 2 2 Phospholipase A2 DUF717 PF05338.7 KFO97221.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF717) DUF3436 PF11918.3 KFO97221.1 - 0.19 11.9 0.1 7.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3436) Guanylate_cyc PF00211.15 KFO97223.1 - 1.7e-87 291.5 0.0 2.5e-57 193.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 KFO97223.1 - 3.3e-25 88.3 0.1 1.1e-24 86.6 0.0 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) Vma12 PF11712.3 KFO97223.1 - 3.1 7.4 6.8 8.1 6.1 0.1 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ArfGap PF01412.13 KFO97225.1 - 3.5e-36 123.5 0.0 9.5e-36 122.1 0.0 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFO97225.1 - 2e-12 47.2 0.1 5.2e-11 42.7 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) SH3_9 PF14604.1 KFO97225.1 - 2.5e-10 39.7 0.1 4.9e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFO97225.1 - 6.7e-10 39.1 0.5 1.9e-09 37.6 0.4 1.9 1 0 0 1 1 1 1 PH domain Ank PF00023.25 KFO97225.1 - 7e-10 38.2 0.3 0.0029 17.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat SH3_1 PF00018.23 KFO97225.1 - 1e-09 37.6 0.3 2.1e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 SH3 domain Ank_5 PF13857.1 KFO97225.1 - 3.9e-07 30.1 0.2 1.6e-05 24.9 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SH3_2 PF07653.12 KFO97225.1 - 9.1e-07 28.2 0.2 2.4e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.1 KFO97225.1 - 2.9e-06 26.9 0.3 0.22 11.8 0.0 3.8 5 0 0 5 5 3 2 Ankyrin repeat Ank_4 PF13637.1 KFO97225.1 - 5e-06 26.8 0.0 0.0017 18.8 0.0 3.0 1 1 0 2 2 2 1 Ankyrin repeats (many copies) PH_3 PF14593.1 KFO97225.1 - 0.016 15.0 0.1 0.062 13.1 0.1 2.0 2 0 0 2 2 2 0 PH domain PH_9 PF15410.1 KFO97225.1 - 0.15 12.2 2.3 4.4 7.4 0.2 3.1 3 1 0 3 3 2 0 Pleckstrin homology domain DUF4404 PF14357.1 KFO97225.1 - 0.42 11.0 10.1 0.32 11.4 3.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF1394 PF07159.7 KFO97226.1 - 2.9e-166 552.0 0.0 3.4e-166 551.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.1 KFO97226.1 - 0.0063 14.7 0.1 0.025 12.7 0.0 1.8 1 1 1 2 2 2 1 WASH complex subunit 7, N-terminal V-ATPase_H_N PF03224.9 KFO97226.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H NUDIX_4 PF14815.1 KFO97226.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain LRAT PF04970.8 KFO97229.1 - 1.1e-13 51.2 0.3 9.7e-12 44.9 0.2 2.3 1 1 0 1 1 1 1 Lecithin retinol acyltransferase NLPC_P60 PF00877.14 KFO97229.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NlpC/P60 family Pkinase PF00069.20 KFO97230.1 - 7.7e-05 21.9 0.0 9.4e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-Nse PF11789.3 KFO97231.1 - 2e-20 72.0 2.7 3.5e-20 71.2 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFO97231.1 - 7.9e-09 35.0 0.9 1.9e-08 33.8 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 KFO97231.1 - 0.00016 21.5 0.2 0.00046 20.0 0.1 1.8 1 1 0 1 1 1 1 U-box domain FadA PF09403.5 KFO97231.1 - 0.00024 21.1 8.5 0.00044 20.2 5.9 1.4 1 0 0 1 1 1 1 Adhesion protein FadA zf-MIZ PF02891.15 KFO97231.1 - 0.00066 19.1 1.5 0.0015 18.0 1.1 1.7 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger Rtf2 PF04641.7 KFO97231.1 - 0.00073 18.8 12.0 0.017 14.3 7.8 2.1 1 1 1 2 2 2 1 Rtf2 RING-finger zf-C4H2 PF10146.4 KFO97231.1 - 0.0013 18.7 8.7 0.0017 18.4 6.1 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein zf-RING_2 PF13639.1 KFO97231.1 - 0.0021 17.8 0.2 0.0038 17.0 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain HalX PF08663.5 KFO97231.1 - 0.016 15.1 1.7 0.042 13.8 1.2 1.7 1 0 0 1 1 1 0 HalX domain zf-rbx1 PF12678.2 KFO97231.1 - 0.083 13.0 0.5 0.17 12.0 0.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Transpos_assoc PF13963.1 KFO97231.1 - 0.62 10.0 5.4 0.54 10.2 0.1 2.8 2 1 1 3 3 3 0 Transposase-associated domain Strumpellin PF10266.4 KFO97232.1 - 0 1571.2 20.1 0 1571.0 13.9 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin EF-hand_9 PF14658.1 KFO97232.1 - 0.057 13.3 0.1 0.46 10.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain SE PF08491.5 KFO97233.1 - 1e-114 382.0 0.1 1.3e-114 381.7 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KFO97233.1 - 4.1e-19 68.8 0.0 7.6e-19 67.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFO97233.1 - 7.3e-14 51.4 0.0 6.9e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFO97233.1 - 0.00019 21.7 0.1 0.0004 20.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFO97233.1 - 0.00038 19.4 0.1 0.61 8.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFO97233.1 - 0.00039 20.3 0.1 0.00097 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 KFO97233.1 - 0.0035 17.3 0.1 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 KFO97233.1 - 0.0061 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KFO97233.1 - 0.0064 15.6 0.0 0.036 13.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 KFO97233.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KFO97233.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GMC_oxred_N PF00732.14 KFO97233.1 - 0.015 14.4 0.0 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_2 PF07992.9 KFO97233.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFO97233.1 - 0.026 13.1 0.1 1.4 7.4 0.1 2.5 2 1 0 3 3 3 0 Tryptophan halogenase Saccharop_dh PF03435.13 KFO97233.1 - 0.031 13.2 0.1 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFO97233.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFO97233.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 KFO97233.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 KFO97233.1 - 0.13 11.0 0.0 0.25 10.1 0.0 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A IMD PF08397.6 KFO97234.1 - 1e-68 230.9 4.5 1.3e-68 230.5 3.1 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Gp58 PF07902.6 KFO97234.1 - 0.13 10.4 0.4 0.18 10.0 0.2 1.1 1 0 0 1 1 1 0 gp58-like protein Complex1_LYR PF05347.10 KFO97235.1 - 1.1e-11 44.3 1.0 1.1e-11 44.3 0.7 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFO97235.1 - 1.1e-08 35.1 0.7 2.2e-08 34.1 0.5 1.4 1 0 0 1 1 1 1 Complex1_LYR-like TatD_DNase PF01026.16 KFO97236.1 - 6.3e-53 179.5 0.0 7.6e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase TRC8_N PF13705.1 KFO97237.1 - 4e-169 563.4 41.1 4.6e-169 563.2 28.5 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.1 KFO97237.1 - 3.8e-11 42.6 9.2 3.8e-11 42.6 6.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFO97237.1 - 1.9e-08 34.2 7.9 2.1e-08 34.1 4.1 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFO97237.1 - 7.6e-07 29.0 7.9 7.6e-07 29.0 5.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO97237.1 - 1.4e-06 27.8 8.0 1.4e-06 27.8 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO97237.1 - 4.3e-06 26.3 4.7 4.3e-06 26.3 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO97237.1 - 1.3e-05 24.8 7.5 1.3e-05 24.8 5.2 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFO97237.1 - 6.3e-05 22.7 5.6 0.00086 19.1 3.9 2.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.1 KFO97237.1 - 0.049 13.7 2.3 0.15 12.2 1.6 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 KFO97237.1 - 0.33 10.9 11.0 1.8 8.6 5.9 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.9 KFO97237.1 - 0.53 9.7 5.3 2.1 7.8 3.7 2.1 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 KFO97237.1 - 4.7 7.0 6.6 0.5 10.1 0.8 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF2453 PF10507.4 KFO97238.1 - 8.1e-45 151.1 3.5 9.6e-45 150.9 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) Romo1 PF10247.4 KFO97238.1 - 0.063 13.4 0.8 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF2273 PF10031.4 KFO97238.1 - 0.13 11.8 0.3 0.13 11.8 0.2 2.6 2 1 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF3789 PF12664.2 KFO97238.1 - 1 8.7 3.3 0.42 9.9 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3789) C2 PF00168.25 KFO97239.1 - 8.6e-68 224.2 0.9 7.9e-14 51.2 0.0 7.4 6 1 0 6 6 6 6 C2 domain FerB PF08150.7 KFO97239.1 - 4.7e-32 109.9 0.1 1.2e-31 108.6 0.1 1.8 1 0 0 1 1 1 1 FerB (NUC096) domain FerI PF08151.7 KFO97239.1 - 8.1e-28 96.2 0.0 2e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain Synaptobrevin PF00957.16 KFO97239.1 - 1.8 8.2 7.6 4.5 6.9 5.2 1.6 1 0 0 1 1 1 0 Synaptobrevin Annexin PF00191.15 KFO97240.1 - 8.3e-98 320.3 12.9 1e-26 92.5 0.1 4.0 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 KFO97240.1 - 0.00029 20.9 0.5 3.6 7.8 0.0 3.9 4 0 0 4 4 4 2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TSLP PF15216.1 KFO97240.1 - 0.069 12.8 0.2 11 5.7 0.0 3.3 4 0 0 4 4 4 0 Thymic stromal lymphopoietin TarH PF02203.10 KFO97240.1 - 0.43 10.3 3.9 10 5.9 0.1 2.9 4 0 0 4 4 4 0 Tar ligand binding domain homologue Kelch_1 PF01344.20 KFO97241.1 - 1.9e-49 164.9 0.4 1.9e-11 43.2 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFO97241.1 - 2.5e-32 109.7 1.2 5.4e-05 23.1 0.0 6.5 2 2 4 6 6 6 6 Kelch motif BTB PF00651.26 KFO97241.1 - 1.9e-26 92.2 1.7 2e-26 92.1 0.2 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFO97241.1 - 2.8e-26 91.0 0.0 0.0029 17.7 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KFO97241.1 - 3.1e-26 90.8 0.0 0.00011 21.8 0.0 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain BACK PF07707.10 KFO97241.1 - 1.5e-25 88.9 1.6 4.7e-25 87.4 0.2 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFO97241.1 - 4e-21 73.8 0.3 0.0028 17.3 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFO97241.1 - 1.6e-17 63.0 3.1 0.0098 15.8 0.0 6.5 6 0 0 6 6 6 5 Kelch motif DUF3342 PF11822.3 KFO97241.1 - 0.0026 16.9 1.2 0.0032 16.6 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) DUF1668 PF07893.8 KFO97241.1 - 0.059 12.4 0.1 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) F-box-like PF12937.2 KFO97242.1 - 0.0017 18.0 0.5 0.0076 15.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFO97242.1 - 0.015 14.9 0.5 0.074 12.7 0.1 2.4 2 0 0 2 2 2 0 F-box domain Elongin_A PF06881.6 KFO97242.1 - 0.019 15.3 0.1 0.064 13.6 0.1 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4047 PF13256.1 KFO97242.1 - 0.057 13.3 1.7 0.22 11.4 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Tissue_fac PF01108.12 KFO97242.1 - 1.1 8.9 3.9 4.6 7.0 0.2 2.9 3 1 0 3 3 3 0 Tissue factor Nt_Gln_amidase PF09764.4 KFO97243.1 - 1.9e-66 222.8 0.0 2.1e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase AAA PF00004.24 KFO97244.1 - 2.7e-49 166.7 0.0 7.7e-42 142.6 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 KFO97244.1 - 2.5e-19 68.9 0.0 7.1e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.1 KFO97244.1 - 3.7e-08 33.5 2.1 2.3e-06 27.7 0.0 3.6 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KFO97244.1 - 2.1e-06 27.9 0.4 0.0015 18.6 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_2 PF07724.9 KFO97244.1 - 1.2e-05 25.2 0.0 5.7e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KFO97244.1 - 1.9e-05 24.1 0.0 0.00045 19.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFO97244.1 - 6.8e-05 22.5 0.0 0.016 14.9 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 KFO97244.1 - 0.0002 21.1 0.2 0.093 12.4 0.0 3.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SR-25 PF10500.4 KFO97244.1 - 0.0017 17.8 5.6 0.0032 16.9 3.9 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_17 PF13207.1 KFO97244.1 - 0.0021 18.8 0.1 0.012 16.3 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KFO97244.1 - 0.0022 18.2 0.0 0.034 14.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFO97244.1 - 0.0056 16.8 0.0 0.049 13.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KFO97244.1 - 0.016 14.6 0.0 0.07 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFO97244.1 - 0.02 13.9 0.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFO97244.1 - 0.024 14.5 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KFO97244.1 - 0.024 13.6 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KFO97244.1 - 0.029 13.5 0.1 0.2 10.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KFO97244.1 - 0.056 13.4 0.3 0.23 11.4 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.1 KFO97244.1 - 0.075 12.5 0.2 1.1 8.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 KFO97244.1 - 0.075 13.0 0.0 0.74 9.8 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.7 KFO97244.1 - 0.086 12.4 0.0 0.9 9.1 0.0 2.7 2 1 0 2 2 2 0 NACHT domain TIP49 PF06068.8 KFO97244.1 - 0.12 11.0 0.0 0.29 9.8 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus Dehydrin PF00257.14 KFO97244.1 - 0.13 12.5 0.5 0.26 11.6 0.4 1.4 1 0 0 1 1 1 0 Dehydrin Parvo_NS1 PF01057.12 KFO97244.1 - 0.19 10.5 0.0 0.4 9.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Homeobox PF00046.24 KFO97245.1 - 1.8e-29 101.1 9.8 1.9e-08 33.7 0.1 4.4 4 0 0 4 4 4 4 Homeobox domain Homez PF11569.3 KFO97245.1 - 6.3e-29 98.8 2.9 7e-22 76.2 0.2 4.2 4 0 0 4 4 4 3 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFO97245.1 - 2.9e-18 65.2 1.1 8.1e-05 22.2 0.0 4.7 4 0 0 4 4 4 4 Homeobox KN domain zf-C2H2 PF00096.21 KFO97245.1 - 0.49 10.8 6.7 4.7 7.7 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97245.1 - 1.2 9.6 5.5 7.2 7.1 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger TPR_19 PF14559.1 KFO97246.1 - 0.018 15.3 1.7 4.9 7.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFO97246.1 - 0.06 13.4 2.4 8 6.6 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KFO97246.1 - 0.1 12.2 1.6 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 KFO97246.1 - 0.11 13.2 1.2 2.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFO97246.1 - 0.14 12.0 0.8 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFO97246.1 - 0.63 10.6 2.6 0.46 11.0 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFO97246.1 - 0.92 9.5 3.1 7.3 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1669 PF07894.7 KFO97247.1 - 1.4e-101 339.4 0.1 1.7e-101 339.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFO97247.1 - 0.0011 18.7 0.1 0.0045 16.7 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain Atx10homo_assoc PF09759.4 KFO97247.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain RabGAP-TBC PF00566.13 KFO97248.1 - 8.8e-10 38.4 3.9 8.8e-10 38.4 2.7 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.27 KFO97248.1 - 2.5e-08 33.4 2.6 0.0048 16.7 0.4 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nbas_N PF15492.1 KFO97248.1 - 0.017 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Xin PF08043.7 KFO97248.1 - 0.12 12.1 1.3 14 5.6 0.0 4.1 4 0 0 4 4 4 0 Xin repeat DER1 PF04511.10 KFO97249.1 - 8.8e-50 168.9 9.1 1e-49 168.7 6.3 1.0 1 0 0 1 1 1 1 Der1-like family DUF3341 PF11821.3 KFO97249.1 - 0.072 12.5 0.1 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Glyco_tranf_2_3 PF13641.1 KFO97250.1 - 3.7e-19 69.4 0.0 5e-18 65.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 KFO97250.1 - 2e-18 66.0 5.6 4e-14 51.9 2.7 3.5 2 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.21 KFO97250.1 - 1.9e-10 40.6 0.0 0.00068 19.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 KFO97250.1 - 2.4e-08 33.9 16.8 1.5e-07 31.3 11.7 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KFO97250.1 - 0.00054 19.3 0.0 0.0012 18.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 PDZ PF00595.19 KFO97251.1 - 7.9e-19 67.6 0.5 1.6e-18 66.6 0.4 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH PF00169.24 KFO97251.1 - 1.2e-10 41.4 0.0 1.3e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 PH domain PDZ_2 PF13180.1 KFO97251.1 - 7.9e-05 22.4 0.1 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 KFO97251.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain MTBP_mid PF14919.1 KFO97252.1 - 2.4e-160 532.8 0.4 3.7e-160 532.2 0.2 1.3 1 0 0 1 1 1 1 MDM2-binding MTBP_C PF14920.1 KFO97252.1 - 2.6e-123 410.4 8.4 4.9e-123 409.5 5.8 1.5 1 0 0 1 1 1 1 MDM2-binding MTBP_N PF14918.1 KFO97252.1 - 4.8e-110 367.2 0.7 9.2e-110 366.3 0.5 1.5 1 0 0 1 1 1 1 MDM2-binding Ribosomal_L13 PF00572.13 KFO97253.1 - 1.8e-05 24.7 0.1 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 VWA PF00092.23 KFO97254.1 - 1.1e-103 344.5 1.3 3.4e-51 173.4 0.0 2.6 3 0 0 3 3 3 2 von Willebrand factor type A domain fn3 PF00041.16 KFO97254.1 - 1.1e-95 313.8 11.9 8.2e-13 48.3 0.0 8.3 8 0 0 8 8 8 8 Fibronectin type III domain Collagen PF01391.13 KFO97254.1 - 2e-37 126.5 168.0 1.7e-08 33.8 20.7 5.5 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 KFO97254.1 - 2.9e-23 82.8 0.0 1.6e-11 44.5 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain SusE PF14292.1 KFO97254.1 - 0.0024 17.6 1.8 2.2 8.0 0.1 4.1 4 0 0 4 4 4 1 SusE outer membrane protein Laminin_G_3 PF13385.1 KFO97254.1 - 0.0045 17.2 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Arylsulfotrans PF05935.6 KFO97254.1 - 0.31 9.4 1.3 8.5 4.7 0.1 2.9 3 0 0 3 3 3 0 Arylsulfotransferase (ASST) DUF587 PF04532.7 KFO97254.1 - 0.33 9.8 0.0 31 3.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF587) DEP PF00610.16 KFO97255.1 - 5.8e-45 150.9 1.8 1.4e-24 85.5 0.2 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_2 PF13180.1 KFO97255.1 - 0.031 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF3658 PF12395.3 KFO97255.1 - 0.055 13.0 0.2 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function PDZ PF00595.19 KFO97255.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) DUF2036 PF09724.4 KFO97256.1 - 6.9e-98 327.7 4.2 8e-98 327.5 2.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Peptidase_M1 PF01433.15 KFO97257.1 - 3.6e-13 49.3 1.1 9.8e-13 47.9 0.7 1.6 1 1 0 1 1 1 1 Peptidase family M1 HEAT_2 PF13646.1 KFO97257.1 - 0.0012 19.0 0.1 0.039 14.2 0.0 3.2 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KFO97257.1 - 0.18 11.9 5.2 2.4 8.4 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Phosphodiest PF01663.17 KFO97258.1 - 1.2e-74 251.8 0.1 1.8e-38 132.8 0.2 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.12 KFO97258.1 - 1.4e-19 69.7 43.8 2.5e-10 40.1 9.5 3.2 3 0 0 3 3 3 2 Somatomedin B domain Endonuclease_NS PF01223.18 KFO97258.1 - 1.2e-12 47.9 0.0 2.7e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.18 KFO97258.1 - 4.5e-05 22.7 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 2 Sulfatase MARVEL PF01284.18 KFO97259.1 - 1.2e-09 38.1 10.6 1.2e-09 38.0 7.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4131 PF13567.1 KFO97259.1 - 0.31 10.4 7.5 0.2 11.0 4.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4227 PF14004.1 KFO97259.1 - 4.4 7.2 6.6 0.51 10.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4227) DUF3687 PF12459.3 KFO97259.1 - 4.8 6.5 10.5 0.17 11.1 1.6 2.3 1 1 1 2 2 2 0 D-Ala-teichoic acid biosynthesis protein Lectin_C PF00059.16 KFO97260.1 - 2.9e-17 63.1 0.0 4.2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.13 KFO97260.1 - 4.2e-13 48.6 46.1 7.3e-08 31.8 13.5 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Death PF00531.17 KFO97261.1 - 9.2e-20 70.2 0.8 1.3e-11 44.0 0.1 2.4 2 0 0 2 2 2 2 Death domain TNFR_c6 PF00020.13 KFO97261.1 - 3e-16 59.1 33.9 2.1e-06 27.6 8.5 4.8 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region tRNA_NucTran2_2 PF13735.1 KFO97261.1 - 0.063 13.0 1.9 1.3 8.8 0.1 2.7 2 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative BCDHK_Adom3 PF10436.4 KFO97261.1 - 0.091 12.2 1.3 0.33 10.4 0.9 1.9 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase GCC2_GCC3 PF07699.8 KFO97261.1 - 0.17 11.5 32.6 0.41 10.2 4.1 4.2 1 1 2 4 4 4 0 GCC2 and GCC3 SAM_2 PF07647.12 KFO97262.1 - 7.9e-18 64.0 1.0 1.1e-17 63.6 0.7 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFO97262.1 - 1.8e-11 44.0 0.9 2.7e-11 43.4 0.6 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFO97262.1 - 8.1e-09 35.1 0.1 1.2e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PAPS_reduct PF01507.14 KFO97262.1 - 0.083 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family YusW PF14039.1 KFO97262.1 - 0.14 12.4 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 YusW-like protein HTH_32 PF13565.1 KFO97262.1 - 0.15 12.8 0.9 0.28 12.0 0.2 1.8 1 1 1 2 2 2 0 Homeodomain-like domain Glyco_transf_64 PF09258.5 KFO97264.1 - 1.2e-105 352.0 0.7 1.8e-105 351.5 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 KFO97264.1 - 3.6e-26 91.8 0.0 8.7e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 Exostosin family KicB PF03882.9 KFO97264.1 - 0.026 13.1 0.2 0.038 12.6 0.1 1.1 1 0 0 1 1 1 0 KicB killing factor Med30 PF11315.3 KFO97265.1 - 1.9e-66 222.8 1.8 2.2e-66 222.6 1.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit 30 UPF0449 PF15136.1 KFO97265.1 - 0.092 12.9 4.1 0.12 12.5 1.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 AKNA PF12443.3 KFO97265.1 - 0.099 12.6 0.9 0.5 10.4 0.2 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF3452 PF11934.3 KFO97265.1 - 0.13 11.6 0.9 5 6.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) NYD-SP28_assoc PF14775.1 KFO97265.1 - 0.63 9.7 5.4 1.4 8.7 3.7 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Cation_efflux PF01545.16 KFO97266.1 - 9.6e-57 192.2 14.9 1.2e-56 191.8 10.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1772 PF08592.6 KFO97266.1 - 0.056 13.1 2.2 1.3 8.7 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Rad21_Rec8_N PF04825.8 KFO97267.1 - 1.4e-43 147.3 0.0 2.7e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KFO97267.1 - 8.1e-23 79.3 0.2 3.3e-22 77.4 0.1 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KFO97267.1 - 2.1e-08 34.0 0.9 6e-08 32.5 0.2 2.1 2 0 0 2 2 2 1 ScpA/B protein V-ATPase_G PF03179.10 KFO97267.1 - 0.02 15.1 3.8 0.06 13.6 2.7 1.7 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Laps PF10169.4 KFO97267.1 - 0.65 10.2 8.7 1 9.5 2.4 2.6 2 0 0 2 2 2 0 Learning-associated protein Fcf1 PF04900.7 KFO97268.1 - 8.3e-29 99.6 1.4 1.8e-28 98.6 0.0 2.1 2 1 1 3 3 3 1 Fcf1 JAB PF01398.16 KFO97269.1 - 4e-18 65.2 0.3 8.3e-18 64.1 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RasGAP_C PF03836.10 KFO97269.1 - 0.11 12.2 4.5 0.11 12.1 0.9 2.3 2 1 0 2 2 2 0 RasGAP C-terminus Apidaecin PF00807.12 KFO97271.1 - 0.051 13.2 1.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Apidaecin RVT_1 PF00078.22 KFO97271.1 - 0.076 12.3 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) GATA PF00320.22 KFO97272.1 - 2.2e-12 46.1 6.1 2.2e-12 46.1 4.2 2.8 2 0 0 2 2 2 1 GATA zinc finger zf-H2C2_5 PF13909.1 KFO97272.1 - 1.2e-05 25.2 85.4 0.00068 19.7 1.6 10.1 10 0 0 10 10 10 7 C2H2-type zinc-finger domain DUF2510 PF10708.4 KFO97274.1 - 3.1 7.3 5.7 64 3.1 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2510) BH4 PF02180.12 KFO97274.1 - 3.3 7.2 8.2 43 3.7 0.3 3.8 2 1 2 4 4 4 0 Bcl-2 homology region 4 SIC PF03482.8 KFO97274.1 - 4.8 6.7 6.7 7.4 6.1 4.7 1.5 1 1 0 1 1 1 0 sic protein zf-H2C2_2 PF13465.1 KFO97275.1 - 1.2e-08 34.8 9.5 0.00031 20.8 1.7 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO97275.1 - 4.2e-06 26.7 2.6 4.2e-06 26.7 1.8 1.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97275.1 - 0.00026 21.1 1.5 0.00037 20.6 1.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFO97275.1 - 0.0022 17.9 4.1 0.0027 17.6 2.8 1.2 1 0 0 1 1 1 1 Zinc ribbon domain zf-C2H2_6 PF13912.1 KFO97275.1 - 0.004 17.0 2.2 0.0064 16.3 1.5 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger XPA_N PF01286.13 KFO97275.1 - 0.048 13.3 1.3 0.06 13.0 0.9 1.3 1 0 0 1 1 1 0 XPA protein N-terminal zf-C2H2_jaz PF12171.3 KFO97275.1 - 0.05 13.7 0.7 0.065 13.4 0.1 1.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.1 KFO97275.1 - 0.067 12.8 1.4 0.068 12.8 1.0 1.4 1 1 0 1 1 1 0 Probable zinc-binding domain LIM PF00412.17 KFO97275.1 - 0.081 13.0 1.4 0.1 12.6 0.9 1.3 1 1 0 1 1 1 0 LIM domain YhfH PF14149.1 KFO97275.1 - 0.27 11.0 2.9 0.4 10.5 1.6 1.7 1 1 1 2 2 2 0 YhfH-like protein zf-AN1 PF01428.11 KFO97275.1 - 0.45 10.4 5.6 0.82 9.6 3.9 1.6 1 1 0 1 1 1 0 AN1-like Zinc finger Zn_Tnp_IS1595 PF12760.2 KFO97275.1 - 0.68 9.7 4.2 1.8 8.4 2.9 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain 7tm_4 PF13853.1 KFO97276.1 - 1.6e-59 199.8 11.3 1.8e-59 199.6 7.8 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO97276.1 - 0.0001 21.5 5.5 0.00012 21.3 3.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.1 KFO97276.1 - 0.3 11.0 1.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) FtsJ PF01728.14 KFO97277.1 - 8.9e-27 94.2 0.0 4e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase PNP_UDP_1 PF01048.15 KFO97278.1 - 2.6e-47 160.7 0.0 2.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily EF-hand_1 PF00036.27 KFO97279.1 - 8.2e-21 71.6 3.0 1e-06 27.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFO97279.1 - 7.9e-20 70.7 3.2 5.4e-10 39.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFO97279.1 - 1.8e-18 64.7 1.6 1.1e-05 24.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFO97279.1 - 9.4e-15 53.2 1.8 0.00065 18.9 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFO97279.1 - 1.7e-07 30.7 2.7 4.9e-06 26.0 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.1 KFO97279.1 - 0.0031 17.1 2.0 3.7 7.2 0.2 3.7 3 1 1 4 4 4 2 EF hand Aminotran_1_2 PF00155.16 KFO97280.1 - 1.1e-93 314.1 0.0 1.2e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aa_trans PF01490.13 KFO97281.1 - 5.3e-55 186.5 24.4 6.5e-55 186.2 16.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFO97281.1 - 2.3e-07 29.9 22.1 5.1e-07 28.8 11.0 2.3 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family SET PF00856.23 KFO97282.1 - 3e-11 43.9 0.1 1.3e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 KFO97282.1 - 1.3e-06 28.3 3.8 1.3e-06 28.3 2.7 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding YlbD_coat PF14071.1 KFO97282.1 - 0.081 12.9 2.4 0.14 12.2 0.6 2.1 2 0 0 2 2 2 0 Putative coat protein RNA_pol_Rpo13 PF12136.3 KFO97282.1 - 0.092 12.4 0.2 0.092 12.4 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Agouti PF05039.7 KFO97283.1 - 2e-22 79.3 11.8 3.3e-22 78.6 8.2 1.4 1 1 0 1 1 1 1 Agouti protein vATP-synt_AC39 PF01992.11 KFO97284.1 - 2.3e-101 339.3 0.0 2.5e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit adh_short PF00106.20 KFO97285.1 - 1.5e-24 86.8 0.0 2.1e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFO97285.1 - 1.1e-11 44.9 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFO97285.1 - 0.00023 20.9 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 KR domain FH2 PF02181.18 KFO97286.1 - 1.2e-79 267.9 4.7 1.6e-79 267.4 3.2 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Na_H_Exchanger PF00999.16 KFO97287.1 - 1.7e-80 270.4 39.2 2e-80 270.1 27.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Clr2 PF10383.4 KFO97287.1 - 0.16 12.0 0.2 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 p25-alpha PF05517.7 KFO97289.1 - 2.7e-58 196.5 6.5 3.1e-58 196.3 4.5 1.0 1 0 0 1 1 1 1 p25-alpha DnaB PF00772.16 KFO97289.1 - 0.0081 16.0 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase N terminal domain zf-DHHC PF01529.15 KFO97290.1 - 1.5e-30 105.8 5.2 1.5e-30 105.8 3.6 1.6 1 1 0 2 2 2 1 DHHC palmitoyltransferase Picorna_P3A PF06363.6 KFO97290.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Picornaviridae P3A protein EGF_CA PF07645.10 KFO97291.1 - 3.5e-19 68.5 31.9 7.6e-08 32.2 5.8 4.0 3 2 1 4 4 4 3 Calcium-binding EGF domain EGF PF00008.22 KFO97291.1 - 9.9e-12 44.5 18.3 5e-09 35.9 5.3 4.3 4 1 0 4 4 4 2 EGF-like domain FXa_inhibition PF14670.1 KFO97291.1 - 1.8e-07 31.1 20.7 8.3e-07 29.0 3.7 3.7 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFO97291.1 - 2.3e-07 30.3 0.7 2.3e-07 30.3 0.5 3.9 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_2 PF07974.8 KFO97291.1 - 0.0011 19.1 11.9 0.0011 19.1 8.3 3.9 3 0 0 3 3 3 1 EGF-like domain EGF_3 PF12947.2 KFO97291.1 - 0.0021 17.9 20.6 0.12 12.3 0.0 3.7 3 0 0 3 3 3 2 EGF domain hEGF PF12661.2 KFO97291.1 - 0.038 14.0 20.6 0.039 14.0 3.4 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF Lectin_C PF00059.16 KFO97292.1 - 1.1e-17 64.6 0.4 2.7e-17 63.3 0.3 1.7 1 0 0 1 1 1 1 Lectin C-type domain CAP PF00188.21 KFO97292.1 - 1.2e-17 64.5 0.0 2.3e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family hEGF PF12661.2 KFO97292.1 - 0.00053 19.8 13.7 0.014 15.4 3.1 3.4 2 0 0 2 2 2 2 Human growth factor-like EGF Chordopox_A33R PF05966.7 KFO97292.1 - 0.036 12.8 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein tRNA-synt_2c PF01411.14 KFO97293.1 - 2.2e-205 683.1 0.0 3.5e-205 682.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFO97293.1 - 2.1e-16 59.4 0.0 4.9e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KFO97293.1 - 9.9e-09 34.7 0.1 9e-08 31.7 0.0 2.5 2 0 0 2 2 2 1 DHHA1 domain Med11 PF10280.4 KFO97293.1 - 0.011 15.8 0.2 0.046 13.7 0.0 2.1 2 1 1 3 3 3 0 Mediator complex protein GTP_EFTU_D4 PF14578.1 KFO97293.1 - 0.015 14.9 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Lipase_GDSL_3 PF14606.1 KFO97293.1 - 0.031 14.0 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MtrB PF05440.7 KFO97293.1 - 0.11 12.4 0.4 0.75 9.8 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B EntA_Immun PF08951.5 KFO97293.1 - 0.28 11.3 1.8 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 Enterocin A Immunity adh_short PF00106.20 KFO97294.1 - 6.7e-05 22.8 0.4 0.099 12.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase PGA2 PF07543.7 KFO97296.1 - 0.19 11.5 1.2 0.22 11.2 0.8 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2890 PF11081.3 KFO97296.1 - 0.35 10.8 4.9 0.35 10.9 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-H2C2_2 PF13465.1 KFO97297.1 - 1.1e-54 180.0 93.1 4.3e-08 33.0 2.1 11.3 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2 PF00096.21 KFO97297.1 - 2e-31 106.3 104.6 0.00026 21.1 0.7 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97297.1 - 2.8e-24 83.6 91.4 0.00093 19.3 2.2 11.3 11 0 0 11 11 11 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO97297.1 - 1.2e-08 34.8 64.5 0.012 15.7 0.3 11.2 9 1 2 11 11 11 5 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFO97297.1 - 2.2e-05 24.4 16.0 0.00019 21.4 0.6 10.7 11 1 0 11 11 11 4 C2H2-type zinc-finger domain zf-met PF12874.2 KFO97297.1 - 0.011 15.9 1.5 0.011 15.9 1.1 10.2 11 0 0 11 11 11 0 Zinc-finger of C2H2 type GAGA PF09237.6 KFO97297.1 - 1.4 8.6 31.0 3 7.5 0.0 7.9 1 1 9 10 10 10 0 GAGA factor zf-C2H2_2 PF12756.2 KFO97297.1 - 2.4 8.3 61.1 2.3 8.3 4.8 7.5 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFO97297.1 - 4.4 7.3 68.0 0.056 13.3 1.4 10.3 11 1 0 11 11 11 0 C2H2-type zinc finger adh_short PF00106.20 KFO97298.1 - 4.3e-13 49.5 0.0 3.3e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFO97298.1 - 2.7e-05 23.9 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFO97299.1 - 3.4e-10 40.1 0.0 1.3e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase WD40 PF00400.27 KFO97300.1 - 5.7e-12 45.0 0.0 0.00024 20.8 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat PTN_MK_C PF01091.13 KFO97300.1 - 0.027 14.4 1.3 0.95 9.4 0.4 2.7 3 0 0 3 3 3 0 PTN/MK heparin-binding protein family, C-terminal domain CPSF_A PF03178.10 KFO97300.1 - 0.051 12.6 0.0 11 5.0 0.0 3.1 1 1 1 2 2 2 0 CPSF A subunit region Nup160 PF11715.3 KFO97300.1 - 0.084 11.0 0.0 0.16 10.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Homeobox_KN PF05920.6 KFO97302.1 - 7e-11 41.6 0.4 1.6e-10 40.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFO97302.1 - 0.0045 16.5 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain CBS PF00571.23 KFO97303.1 - 7.3e-08 32.0 0.0 4e-06 26.5 0.0 2.4 2 1 0 2 2 2 2 CBS domain Poxvirus_B22R_C PF13168.1 KFO97303.1 - 0.00035 19.9 0.0 0.00043 19.6 0.0 1.1 1 0 0 1 1 1 1 Poxvirus B22R protein C-terminal PALP PF00291.20 KFO97304.1 - 9.2e-17 61.2 0.0 9.8e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Integrase_Zn PF02022.14 KFO97304.1 - 0.022 14.1 0.5 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Integrase Zinc binding domain FIST PF08495.5 KFO97304.1 - 0.059 12.5 0.2 0.13 11.3 0.2 1.5 1 1 0 1 1 1 0 FIST N domain IF-2 PF11987.3 KFO97304.1 - 0.095 12.5 0.0 1.3 8.9 0.0 2.0 1 1 1 2 2 2 0 Translation-initiation factor 2 DUF3798 PF12683.2 KFO97304.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Methyltransf_16 PF10294.4 KFO97304.1 - 0.17 11.3 0.2 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Putative methyltransferase zf-CCCH PF00642.19 KFO97306.1 - 1.3e-13 50.2 16.8 5.9e-07 29.0 2.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KFO97306.1 - 1e-08 34.9 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO97306.1 - 3.7e-07 29.6 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO97306.1 - 0.00034 20.5 0.1 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 KFO97306.1 - 0.017 15.0 1.4 0.34 10.9 0.3 2.9 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) KMP11 PF03037.11 KFO97306.1 - 0.017 15.7 0.4 0.73 10.4 0.2 2.2 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Nup35_RRM_2 PF14605.1 KFO97306.1 - 0.03 14.0 0.2 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Benyvirus_14KDa PF07255.6 KFO97306.1 - 0.074 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Benyvirus 14KDa protein HSP20 PF00011.16 KFO97307.1 - 3.7e-29 100.5 0.0 4.6e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 KFO97307.1 - 2.4e-26 91.6 1.1 4.7e-26 90.7 0.8 1.5 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal Myf5 PF12232.3 KFO97307.1 - 0.13 12.9 0.4 0.19 12.3 0.3 1.3 1 0 0 1 1 1 0 Myogenic determination factor 5 Pkinase PF00069.20 KFO97308.1 - 7.6e-78 261.2 0.2 2.6e-77 259.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97308.1 - 1.1e-40 139.3 0.0 2.1e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO97308.1 - 7.4e-08 31.6 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFO97308.1 - 0.095 12.0 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CCDC144C PF14915.1 KFO97309.1 - 0.00013 20.9 3.4 0.00023 20.1 2.4 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF972 PF06156.8 KFO97309.1 - 0.001 19.3 2.3 0.001 19.3 1.6 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF972) HEAT PF02985.17 KFO97309.1 - 0.0036 17.2 0.3 0.016 15.2 0.2 2.2 1 0 0 1 1 1 1 HEAT repeat DUF3584 PF12128.3 KFO97309.1 - 0.0039 14.5 4.0 0.0055 14.1 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) VHS PF00790.14 KFO97309.1 - 0.0057 16.2 0.1 0.43 10.2 0.0 2.6 2 0 0 2 2 2 1 VHS domain RasGEF_N_2 PF14663.1 KFO97309.1 - 0.0065 16.3 0.0 0.026 14.4 0.0 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Spc7 PF08317.6 KFO97309.1 - 0.016 13.9 8.0 0.028 13.1 5.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 KFO97309.1 - 0.077 12.0 6.4 0.15 11.1 4.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP_synt_I PF03899.10 KFO97309.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 ATP synthase I chain Atg14 PF10186.4 KFO97309.1 - 0.11 11.4 8.9 1.3 7.9 5.1 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF383 PF04063.9 KFO97309.1 - 0.12 11.9 2.4 0.23 10.9 1.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF383) DUF1409 PF07197.7 KFO97309.1 - 0.13 12.3 8.4 0.039 14.0 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Remorin_C PF03763.8 KFO97309.1 - 0.15 11.6 4.4 0.28 10.7 3.1 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region PVL_ORF50 PF07768.6 KFO97309.1 - 0.25 11.3 3.0 0.65 10.0 2.1 1.6 1 0 0 1 1 1 0 PVL ORF-50-like family Mnd1 PF03962.10 KFO97309.1 - 0.27 10.8 7.7 0.28 10.8 4.5 1.6 2 0 0 2 2 2 0 Mnd1 family Lectin_N PF03954.9 KFO97309.1 - 0.39 10.1 3.6 3.4 7.0 0.1 2.8 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain THOC7 PF05615.8 KFO97309.1 - 0.83 9.9 10.5 0.37 11.0 5.2 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 Spc42p PF11544.3 KFO97309.1 - 1.2 9.0 6.5 0.58 10.1 1.4 2.5 2 1 0 2 2 2 0 Spindle pole body component Spc42p DUF4259 PF14078.1 KFO97309.1 - 2.6 8.5 5.7 5.5 7.4 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4259) TPR_MLP1_2 PF07926.7 KFO97309.1 - 3.6 7.3 14.7 0.032 13.9 4.1 2.0 3 0 0 3 3 2 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.1 KFO97309.1 - 6.7 6.1 16.5 0.23 10.8 6.6 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Nop52 PF05997.7 KFO97310.1 - 1.4e-66 224.0 3.1 1.4e-66 224.0 2.1 2.0 2 0 0 2 2 2 1 Nucleolar protein,Nop52 PfkB PF00294.19 KFO97311.1 - 3.4e-17 62.5 0.0 5e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFO97311.1 - 9.6e-07 28.2 0.2 3e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HpcH_HpaI PF03328.9 KFO97311.1 - 0.0038 16.1 0.0 0.0075 15.1 0.0 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Latrophilin PF02354.11 KFO97313.1 - 5.2e-117 390.6 9.5 8.5e-117 389.9 6.6 1.3 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.11 KFO97313.1 - 5.3e-95 317.4 2.6 9.8e-95 316.5 1.8 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain DUF3497 PF12003.3 KFO97313.1 - 2e-82 275.7 6.6 3e-82 275.2 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) 7tm_2 PF00002.19 KFO97313.1 - 1.5e-70 237.0 19.0 2.4e-70 236.3 13.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Gal_Lectin PF02140.13 KFO97313.1 - 1.7e-23 82.6 0.8 1.7e-23 82.6 0.5 2.1 2 0 0 2 2 2 1 Galactose binding lectin domain GPS PF01825.16 KFO97313.1 - 1.3e-15 57.1 9.0 3.2e-15 55.9 6.2 1.7 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 KFO97313.1 - 1e-06 28.6 0.7 3e-06 27.1 0.5 1.9 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 KFO97313.1 - 0.0016 17.4 14.8 0.0028 16.5 10.2 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF3481 PF11980.3 KFO97313.1 - 0.049 13.4 0.3 1.2 8.9 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) HLH PF00010.21 KFO97314.1 - 1.6e-07 30.8 0.2 5e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhoU PF01895.14 KFO97314.1 - 0.58 10.6 0.8 1.2 9.6 0.6 1.5 1 0 0 1 1 1 0 PhoU domain Acetyltransf_1 PF00583.19 KFO97315.1 - 2.3e-16 59.5 0.0 3.3e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFO97315.1 - 3.6e-10 39.8 0.1 6.2e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFO97315.1 - 2.4e-07 30.8 0.1 2.6e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFO97315.1 - 3.1e-07 30.5 0.0 3.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFO97315.1 - 2.7e-06 27.3 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFO97315.1 - 0.00011 22.1 0.0 0.00021 21.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFO97315.1 - 0.00016 21.3 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KFO97315.1 - 0.00069 19.8 0.0 0.00081 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Epsilon_antitox PF08998.6 KFO97315.1 - 0.015 15.2 0.1 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial epsilon antitoxin DUF3749 PF12568.3 KFO97315.1 - 0.05 13.1 0.0 0.072 12.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2206 PF09971.4 KFO97315.1 - 0.1 11.3 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) ATP-synt_ab PF00006.20 KFO97316.1 - 2.4e-105 350.7 0.0 2.9e-105 350.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFO97316.1 - 9.3e-18 64.7 0.2 1.8e-17 63.8 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain AAA_14 PF13173.1 KFO97316.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFO97316.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFO97316.1 - 0.16 11.9 0.0 3.1 7.7 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Yippee-Mis18 PF03226.9 KFO97317.1 - 0.0026 17.7 0.8 0.017 15.1 0.3 2.1 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 KFO97317.1 - 1 9.2 4.6 15 5.5 3.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 KFO97317.1 - 4.6 7.7 5.8 2.6 8.5 0.3 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF1693 PF07984.7 KFO97318.1 - 4.1e-170 565.0 0.9 4.8e-170 564.8 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) Peptidase_U32 PF01136.14 KFO97318.1 - 0.12 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family U32 CRAL_TRIO_2 PF13716.1 KFO97319.1 - 3.2e-32 111.4 1.3 6.1e-32 110.5 0.9 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.16 KFO97319.1 - 8.3e-25 86.9 0.0 1.5e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.15 KFO97319.1 - 2.1e-07 30.5 0.8 4.9e-07 29.3 0.5 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain WD40 PF00400.27 KFO97320.1 - 1.1e-75 247.0 18.0 2.6e-10 39.7 0.0 10.8 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 KFO97320.1 - 1.1e-25 89.7 0.2 2.3e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 KFO97320.1 - 0.0004 19.2 2.1 0.023 13.4 0.4 3.9 1 1 2 5 5 5 2 Nup133 N terminal like Nup160 PF11715.3 KFO97320.1 - 0.34 8.9 8.1 2.2 6.2 0.0 4.4 3 2 0 4 4 4 0 Nucleoporin Nup120/160 PapD-like PF14874.1 KFO97321.1 - 1.1e-10 41.2 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Flagellar-associated PapD-like T-box PF00907.17 KFO97322.1 - 4.8e-86 286.9 0.1 6.7e-86 286.4 0.0 1.2 1 0 0 1 1 1 1 T-box tRNA-synt_1b PF00579.20 KFO97323.1 - 3.9e-68 229.6 0.0 5.1e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FMN_dh PF01070.13 KFO97324.1 - 2.7e-131 437.6 0.2 8.3e-131 436.0 0.2 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFO97324.1 - 1.4e-06 27.5 0.5 3.6e-06 26.1 0.2 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFO97324.1 - 3.2e-05 23.0 0.2 4.7e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KFO97324.1 - 0.0019 17.5 0.3 0.0099 15.1 0.0 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein Dus PF01207.12 KFO97324.1 - 0.0099 14.7 0.5 1.7 7.4 0.1 2.6 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.9 KFO97324.1 - 0.017 14.1 0.1 0.62 9.1 0.1 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 KFO97324.1 - 0.27 10.3 2.1 0.44 9.6 1.4 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Glyco_hydro_47 PF01532.15 KFO97325.1 - 2.5e-154 514.2 0.0 3.1e-154 513.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 OmpH PF03938.9 KFO97325.1 - 1 9.3 5.2 2.3 8.1 3.6 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP-synt_B PF00430.13 KFO97325.1 - 2.2 8.0 7.8 4.2 7.1 5.4 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) C2-set_2 PF08205.7 KFO97326.1 - 1.7e-07 31.0 0.1 3.5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFO97326.1 - 4.8e-05 23.2 0.5 0.004 17.0 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain C1-set PF07654.10 KFO97326.1 - 9.3e-05 22.3 0.2 0.042 13.8 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin C1-set domain I-set PF07679.11 KFO97326.1 - 0.005 16.6 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFO97326.1 - 0.066 13.7 1.1 0.21 12.0 0.4 2.2 2 1 0 2 2 2 0 Immunoglobulin domain ANF_receptor PF01094.23 KFO97327.1 - 3.8e-107 358.0 0.0 4.8e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFO97327.1 - 3.7e-83 278.5 28.4 6.2e-83 277.7 19.7 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFO97327.1 - 2.6e-19 68.6 10.5 7.9e-19 67.1 7.3 1.9 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFO97327.1 - 3e-13 49.8 0.0 5.5e-12 45.6 0.0 2.5 2 1 0 2 2 2 1 Periplasmic binding protein GCC2_GCC3 PF07699.8 KFO97327.1 - 0.0068 15.9 4.5 0.014 14.9 2.5 1.9 1 1 0 1 1 1 1 GCC2 and GCC3 PIG-P PF08510.7 KFO97327.1 - 1.7 8.2 6.6 0.73 9.4 1.0 2.6 2 0 0 2 2 2 0 PIG-P Cystatin PF00031.16 KFO97328.1 - 3e-12 46.5 0.1 3.2e-12 46.3 0.1 1.0 1 0 0 1 1 1 1 Cystatin domain Cystatin PF00031.16 KFO97329.1 - 2.7e-09 37.0 0.1 2.8e-09 36.9 0.1 1.0 1 0 0 1 1 1 1 Cystatin domain Cid2 PF09774.4 KFO97330.1 - 1.2e-26 93.6 4.5 2.2e-26 92.7 3.1 1.4 1 1 0 1 1 1 1 Caffeine-induced death protein 2 TACC PF05010.9 KFO97330.1 - 0.00051 19.8 1.3 0.00062 19.5 0.9 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) GAS PF13851.1 KFO97330.1 - 0.0039 16.4 2.5 0.0045 16.2 1.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF837 PF05769.6 KFO97330.1 - 0.013 15.0 3.3 0.018 14.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Mnd1 PF03962.10 KFO97330.1 - 0.097 12.3 6.6 0.15 11.6 4.6 1.3 1 1 0 1 1 1 0 Mnd1 family DUF1075 PF06388.6 KFO97331.1 - 7.4e-42 142.4 0.2 8e-42 142.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Arm PF00514.18 KFO97332.1 - 5.1e-86 279.8 15.3 1.3e-13 50.2 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 KFO97332.1 - 8.5e-27 93.1 7.5 1.7e-26 92.1 5.2 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 KFO97332.1 - 1.2e-21 76.7 0.1 2.9e-08 33.8 0.0 5.6 2 1 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 KFO97332.1 - 1.7e-16 60.1 5.2 2.5e-05 24.5 0.0 5.8 5 1 1 6 6 6 4 HEAT-like repeat HEAT PF02985.17 KFO97332.1 - 1.1e-10 40.6 9.8 0.00071 19.4 0.0 7.3 10 0 0 10 10 10 3 HEAT repeat RICTOR_V PF14668.1 KFO97332.1 - 2.4e-05 24.1 3.9 0.36 10.7 0.0 5.0 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.8 KFO97332.1 - 3.3e-05 23.1 0.3 0.34 9.9 0.1 3.2 2 2 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.3 KFO97332.1 - 0.00017 21.4 0.2 0.21 11.5 0.0 4.2 3 2 1 4 4 4 2 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFO97332.1 - 0.033 12.4 1.0 0.11 10.7 0.1 2.0 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KFO97332.1 - 2.1 9.0 8.0 8.7 7.1 0.2 5.0 6 1 0 6 6 6 0 PBS lyase HEAT-like repeat F-box PF00646.28 KFO97333.1 - 0.0028 17.2 0.3 0.009 15.6 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFO97333.1 - 0.0037 16.9 0.1 0.01 15.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like zf-TRAF PF02176.13 KFO97333.1 - 0.011 16.0 5.7 0.011 16.0 4.0 4.8 3 2 1 4 4 4 0 TRAF-type zinc finger ASC PF00858.19 KFO97334.1 - 2e-110 369.4 10.1 2.4e-110 369.1 7.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Spin-Ssty PF02513.12 KFO97335.1 - 1.6e-77 254.8 6.7 1.2e-27 95.2 0.1 3.2 3 0 0 3 3 3 3 Spin/Ssty Family GETHR PF05671.6 KFO97336.1 - 9.2e-06 24.6 38.6 0.064 12.4 6.6 3.6 1 1 3 4 4 4 4 GETHR pentapeptide repeat (5 copies) zf-MIZ PF02891.15 KFO97337.1 - 9.8e-23 79.4 4.8 9.8e-23 79.4 3.3 2.2 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFO97337.1 - 4.1e-05 23.0 1.3 4.1e-05 23.0 0.9 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Pro_isomerase PF00160.16 KFO97338.1 - 3.2e-45 154.1 0.3 3.5e-45 153.9 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PLAC9 PF15205.1 KFO97339.1 - 3.4e-07 30.4 0.0 3.4e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Placenta-specific protein 9 PALP PF00291.20 KFO97340.1 - 1.9e-56 191.5 0.2 2.4e-56 191.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.20 KFO97340.1 - 0.0035 16.7 0.0 0.0084 15.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KFO97340.1 - 0.0073 16.0 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain DUF3239 PF11580.3 KFO97340.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) DUF4499 PF14934.1 KFO97341.1 - 1.6e-32 111.3 6.4 1.8e-32 111.1 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF663 PF04950.7 KFO97342.1 - 3.7e-88 295.3 0.0 3.7e-88 295.3 0.0 2.4 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFO97342.1 - 5.7e-29 99.4 0.0 1.8e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KFO97342.1 - 2.8e-07 30.1 0.1 0.00014 21.3 0.0 2.9 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 KFO97342.1 - 0.00013 21.7 0.2 0.00013 21.7 0.1 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KFO97342.1 - 0.00057 19.8 0.2 0.0027 17.6 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFO97342.1 - 0.0039 17.1 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 KFO97342.1 - 0.019 15.4 1.1 0.062 13.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KFO97342.1 - 0.022 14.9 0.1 0.022 14.9 0.1 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFO97342.1 - 0.024 14.5 0.0 0.093 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFO97342.1 - 0.039 14.1 0.1 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 KFO97342.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFO97342.1 - 0.041 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gly_acyl_tr_C PF08444.5 KFO97342.1 - 0.046 13.7 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region CAP PF00188.21 KFO97343.1 - 5.6e-22 78.5 0.5 6.7e-22 78.2 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BLOC1_2 PF10046.4 KFO97344.1 - 0.0044 17.1 0.2 0.024 14.7 0.0 1.9 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.8 KFO97344.1 - 0.028 13.3 0.4 0.036 12.9 0.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 CAP_C PF08603.6 KFO97344.1 - 0.066 12.5 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal DUF1664 PF07889.7 KFO97344.1 - 0.11 12.2 0.2 0.41 10.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PDZ PF00595.19 KFO97345.1 - 5.7e-11 42.4 0.0 9.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PB1 PF00564.19 KFO97345.1 - 4e-10 39.2 0.0 9.9e-10 37.9 0.0 1.7 2 0 0 2 2 2 1 PB1 domain PDZ_2 PF13180.1 KFO97345.1 - 0.023 14.5 0.1 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain HEAT_2 PF13646.1 KFO97346.1 - 6.4e-06 26.3 3.1 0.00012 22.3 0.1 2.9 1 1 2 3 3 3 1 HEAT repeats Arm PF00514.18 KFO97346.1 - 0.0026 17.5 3.2 1.1 9.1 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFO97346.1 - 0.075 13.1 0.1 0.6 10.3 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 KFO97346.1 - 0.48 10.9 2.3 59 4.3 0.1 3.9 3 1 1 4 4 4 0 HEAT-like repeat Geminin PF07412.7 KFO97347.1 - 2.6e-78 262.3 7.5 2.9e-78 262.1 5.2 1.0 1 0 0 1 1 1 1 Geminin DUF342 PF03961.8 KFO97347.1 - 0.0078 14.6 3.6 0.0087 14.5 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KFO97347.1 - 0.012 15.6 1.8 0.012 15.6 1.3 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UvsY PF11056.3 KFO97347.1 - 0.036 14.2 3.5 0.087 12.9 0.9 2.0 1 1 1 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY DUF1342 PF07072.6 KFO97347.1 - 0.038 13.6 3.6 0.61 9.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) Snapin_Pallidin PF14712.1 KFO97347.1 - 0.048 13.9 0.6 0.1 12.8 0.4 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Vps51 PF08700.6 KFO97347.1 - 0.069 13.0 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Vps51/Vps67 DUF3688 PF12461.3 KFO97347.1 - 0.073 13.4 2.6 0.1 12.9 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3688) DivIC PF04977.10 KFO97347.1 - 0.13 11.8 5.6 0.056 12.9 1.4 2.0 1 1 1 2 2 2 0 Septum formation initiator Spc42p PF11544.3 KFO97347.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF641 PF04859.7 KFO97347.1 - 0.23 11.1 4.7 0.13 12.0 1.6 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Herpes_BLRF2 PF05812.7 KFO97347.1 - 0.23 11.2 3.9 0.62 9.8 0.8 2.1 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein HALZ PF02183.13 KFO97347.1 - 0.43 10.3 6.0 3.1 7.5 0.7 2.8 1 1 1 2 2 2 0 Homeobox associated leucine zipper Nefa_Nip30_N PF10187.4 KFO97347.1 - 0.56 10.4 7.5 0.57 10.3 4.2 1.8 1 1 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Laminin_II PF06009.7 KFO97347.1 - 0.75 9.5 5.6 0.092 12.5 0.6 1.8 2 0 0 2 2 2 0 Laminin Domain II DivIVA PF05103.8 KFO97347.1 - 1.1 9.3 9.5 0.16 11.9 3.4 1.9 2 0 0 2 2 2 0 DivIVA protein Bap31 PF05529.7 KFO97347.1 - 1.9 7.8 5.3 3.1 7.2 3.7 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Val_tRNA-synt_C PF10458.4 KFO97347.1 - 2.4 8.3 12.8 2 8.5 0.5 2.8 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm CCDC-167 PF15188.1 KFO97347.1 - 4.6 7.2 11.5 3.5 7.6 6.6 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4566 PF15130.1 KFO97348.1 - 4.1e-148 491.0 2.0 4.6e-148 490.9 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4566) 4HBT PF03061.17 KFO97349.1 - 6.6e-14 51.8 0.3 1.1e-13 51.1 0.0 1.4 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.1 KFO97349.1 - 8.4e-05 22.4 0.1 0.0001 22.1 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 KFO97349.1 - 0.0086 16.0 0.2 0.038 13.9 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4442) Exo_endo_phos PF03372.18 KFO97350.1 - 5.6e-16 59.2 0.0 7.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.1 KFO97350.1 - 8.5e-10 38.0 0.1 1.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain 7tm_1 PF00001.16 KFO97351.1 - 6.2e-63 212.3 16.3 7.5e-63 212.0 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97351.1 - 1.3e-08 34.2 14.0 1.7e-08 33.9 9.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFO97351.1 - 3e-08 33.1 14.2 4.3e-06 26.0 9.8 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 KFO97351.1 - 1.8e-05 24.0 12.2 2.4e-05 23.6 8.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srd PF10317.4 KFO97351.1 - 4.9e-05 22.4 19.0 0.0024 16.9 13.2 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Bac_rhodopsin PF01036.13 KFO97351.1 - 0.44 9.8 12.3 0.14 11.4 4.1 2.4 2 1 0 2 2 2 0 Bacteriorhodopsin-like protein Myelin_MBP PF01669.12 KFO97352.1 - 6e-50 168.6 6.2 9.5e-50 167.9 4.3 1.3 1 0 0 1 1 1 1 Myelin basic protein zf-H2C2_2 PF13465.1 KFO97353.1 - 1e-73 240.2 98.5 3.6e-10 39.6 0.2 13.9 14 1 0 14 14 14 11 Zinc-finger double domain zf-C2H2 PF00096.21 KFO97353.1 - 2.8e-60 197.1 93.4 1.5e-06 28.1 1.7 12.1 11 1 1 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97353.1 - 4.6e-46 151.8 77.6 6.1e-05 23.0 0.1 12.1 11 1 1 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO97353.1 - 1.5e-31 107.7 52.9 0.00021 21.2 2.5 11.9 11 1 1 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFO97353.1 - 7.7e-11 41.9 64.8 2.3e-05 24.4 2.0 9.0 4 2 3 8 8 8 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFO97353.1 - 2.5e-07 30.7 59.1 0.12 12.5 1.4 10.9 1 1 10 11 11 11 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFO97353.1 - 6.6e-07 29.3 71.0 0.042 14.0 0.2 11.3 10 1 1 11 11 11 4 Zinc-finger of C2H2 type Imm-NTF2-2 PF15631.1 KFO97353.1 - 0.00014 21.8 0.0 3.7 7.6 0.0 4.9 5 0 0 5 5 5 1 NTF2 fold immunity protein zf-C2HC_2 PF13913.1 KFO97353.1 - 0.018 14.6 57.8 0.12 12.0 0.5 10.0 9 1 1 10 10 10 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFO97353.1 - 0.038 13.9 51.0 0.44 10.5 0.2 10.2 12 0 0 12 12 11 0 zinc-finger GAGA PF09237.6 KFO97353.1 - 0.28 10.8 23.7 0.31 10.6 0.1 6.4 2 2 5 7 7 7 0 GAGA factor zf-C2H2_6 PF13912.1 KFO97353.1 - 0.48 10.3 68.5 0.3 11.0 0.3 11.7 11 1 1 12 12 12 0 C2H2-type zinc finger zf-CHCC PF10276.4 KFO97353.1 - 0.49 10.2 0.1 0.49 10.2 0.0 9.4 11 0 0 11 11 11 0 Zinc-finger domain zf-C2H2 PF00096.21 KFO97354.1 - 1.1e-27 94.6 84.9 0.00013 22.0 3.0 10.7 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97354.1 - 4.1e-22 76.8 77.8 0.0022 18.1 2.5 10.8 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO97354.1 - 6.9e-09 35.5 2.0 6.9e-09 35.5 1.4 13.7 14 1 0 14 14 14 4 Zinc-finger double domain zf-Di19 PF05605.7 KFO97354.1 - 0.00031 20.7 39.1 0.67 10.1 0.1 6.6 5 2 1 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFO97354.1 - 0.0016 18.5 0.4 0.0016 18.5 0.3 9.2 11 0 0 11 11 11 2 C2H2-type zinc-finger domain DUF629 PF04780.7 KFO97354.1 - 0.011 14.2 8.4 0.28 9.6 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 KFO97354.1 - 0.024 14.7 48.4 0.047 13.8 0.3 7.8 5 2 3 8 8 8 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFO97354.1 - 0.82 9.4 39.8 0.085 12.5 1.5 7.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type XPA_N PF01286.13 KFO97354.1 - 2.7 7.7 21.0 5.3 6.8 0.2 6.3 6 0 0 6 6 6 0 XPA protein N-terminal zf-C2H2_2 PF12756.2 KFO97355.1 - 8.3e-13 48.3 20.0 0.0037 17.3 0.7 5.5 4 2 1 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KFO97355.1 - 1.7e-09 37.4 29.0 0.069 13.5 1.0 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97355.1 - 1.3e-07 31.4 19.8 0.058 13.7 1.6 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO97355.1 - 0.0001 22.0 25.8 0.13 12.1 0.4 5.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 KFO97355.1 - 0.0048 17.0 9.4 0.018 15.2 1.4 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFO97355.1 - 0.066 12.9 0.2 0.066 12.9 0.1 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF678 PF05077.7 KFO97355.1 - 0.08 12.9 7.1 4.7 7.2 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF678) PyrI_C PF02748.10 KFO97355.1 - 0.092 12.1 1.6 1.7 8.1 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 KFO97355.1 - 0.21 11.5 11.6 4.7 7.2 0.0 5.4 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFO97355.1 - 0.46 10.6 22.8 0.19 11.9 0.6 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding ADH_zinc_N PF00107.21 KFO97356.1 - 7.1e-29 99.9 0.0 1.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFO97356.1 - 1.1e-10 41.2 0.1 9.2e-08 31.8 0.0 3.2 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFO97356.1 - 4.8e-10 40.4 0.0 2.5e-09 38.1 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KFO97356.1 - 0.074 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding zf-H2C2_2 PF13465.1 KFO97357.1 - 2.1e-35 119.2 46.0 1e-07 31.8 0.7 7.2 7 0 0 7 7 7 6 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFO97357.1 - 3e-14 52.2 37.6 0.0012 18.9 0.4 7.3 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFO97357.1 - 1.1e-09 37.9 51.2 0.00019 21.5 1.4 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97357.1 - 3.8e-09 36.2 49.7 0.0073 16.5 1.3 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFO97357.1 - 0.083 12.5 0.1 0.083 12.5 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-piccolo PF05715.8 KFO97357.1 - 0.1 12.6 2.8 0.1 12.6 0.2 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger C1_3 PF07649.7 KFO97357.1 - 0.81 9.7 14.0 21 5.2 0.2 5.3 5 0 0 5 5 5 0 C1-like domain zf-Di19 PF05605.7 KFO97357.1 - 5.4 7.2 25.8 3 8.0 3.1 4.7 1 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 KFO97357.1 - 5.9 6.6 18.7 1.1 8.9 0.6 4.4 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 KFO97359.1 - 4.6e-09 36.1 114.7 1.2e-05 25.3 0.5 15.8 17 0 0 17 17 17 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFO97359.1 - 0.0044 17.1 3.0 0.0044 17.1 2.1 12.6 14 0 0 14 14 14 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO97359.1 - 0.0053 16.9 2.5 0.0053 16.9 1.7 8.4 8 0 0 8 8 8 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFO97359.1 - 0.0097 16.2 1.7 0.0097 16.2 1.2 17.7 18 0 0 18 18 18 7 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KFO97359.1 - 0.011 15.8 0.6 0.011 15.8 0.4 13.3 7 6 7 14 14 14 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KFO97359.1 - 0.012 15.7 2.4 0.012 15.7 1.7 15.9 16 0 0 16 16 16 0 C2H2-type zinc-finger domain Cytochrome-c551 PF10643.4 KFO97359.1 - 0.16 11.2 1.0 0.67 9.1 0.0 2.6 3 0 0 3 3 3 0 Photosystem P840 reaction-centre cytochrome c-551 Peptidase_M20 PF01546.23 KFO97360.1 - 9.9e-35 119.7 0.0 1.5e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFO97360.1 - 6.6e-18 64.4 0.0 2.9e-17 62.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Cyt-b5 PF00173.23 KFO97362.1 - 7.7e-08 32.0 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TIM21 PF08294.6 KFO97363.1 - 8.1e-47 158.5 0.3 9.7e-47 158.2 0.2 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KFO97363.1 - 7.5e-06 25.4 0.1 2e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 F-box-like PF12937.2 KFO97364.1 - 3e-11 42.8 0.0 6.1e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFO97364.1 - 6.2e-08 32.0 0.0 1.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain CUB PF00431.15 KFO97365.1 - 9.9e-40 135.0 0.2 1.2e-25 89.6 0.0 2.5 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.13 KFO97365.1 - 1.2e-06 28.2 3.9 1.2e-06 28.2 2.7 2.6 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A C1q PF00386.16 KFO97366.1 - 1.1e-29 103.0 0.3 1.2e-29 102.8 0.2 1.0 1 0 0 1 1 1 1 C1q domain SOCS_box PF07525.11 KFO97369.1 - 1.2e-14 53.8 1.7 2.8e-14 52.6 1.1 1.7 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 KFO97369.1 - 5.3e-13 48.5 0.0 1.5e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Yae1_N PF09811.4 KFO97370.1 - 4.3e-14 51.7 39.5 6.3e+02 -0.0 27.4 3.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RTTN_N PF14726.1 KFO97371.1 - 6.6e-27 93.9 0.0 6.6e-27 93.9 0.0 5.9 7 0 0 7 7 7 1 Rotatin, an armadillo repeat protein, centriole functioning IRS PF02174.12 KFO97372.1 - 2e-29 101.1 0.0 3.5e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 KFO97372.1 - 0.00068 19.7 0.5 0.0016 18.6 0.3 1.6 1 0 0 1 1 1 1 PH domain Myosin_tail_1 PF01576.14 KFO97373.1 - 6.5e-05 20.8 5.5 6.5e-05 20.8 3.8 3.0 3 0 0 3 3 3 2 Myosin tail Thioredoxin PF00085.15 KFO97374.1 - 5.3e-27 93.5 0.0 1.6e-25 88.7 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 KFO97374.1 - 1.8e-25 89.8 0.2 3.7e-23 82.2 0.4 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFO97374.1 - 6.4e-07 29.5 0.2 1.2e-05 25.4 0.0 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFO97374.1 - 0.00047 20.2 0.2 0.055 13.5 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFO97374.1 - 0.021 14.8 0.3 0.087 12.8 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like SH3_5 PF08460.5 KFO97374.1 - 0.053 13.4 0.2 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Transglut_C PF00927.17 KFO97375.1 - 1.2e-29 102.4 0.0 5.8e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 KFO97375.1 - 3.7e-12 46.4 0.1 7.7e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sulfotransfer_1 PF00685.22 KFO97376.1 - 3.7e-13 49.3 0.0 3.7e-12 46.0 0.0 2.8 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFO97376.1 - 0.0018 19.2 0.0 0.0077 17.1 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase family Cadherin PF00028.12 KFO97380.1 - 1.6e-85 281.4 8.1 9.8e-20 70.6 0.1 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFO97380.1 - 1.2e-55 187.6 0.1 2.5e-55 186.6 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFO97380.1 - 5.8e-06 25.7 0.0 1.2 8.7 0.0 4.6 4 1 0 4 4 4 2 Cadherin-like 7tm_1 PF00001.16 KFO97381.1 - 2.8e-39 134.7 24.1 3.6e-37 127.9 16.7 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97381.1 - 1.4e-11 44.0 15.7 3.8e-09 36.0 10.9 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO97381.1 - 0.00017 20.8 8.7 0.00017 20.8 6.1 3.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3278 PF11683.3 KFO97381.1 - 0.0055 16.6 3.1 0.0055 16.6 2.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3278) Git3_C PF11970.3 KFO97381.1 - 2.2 8.1 6.2 0.17 11.6 0.5 2.1 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KFO97382.1 - 5e-41 140.5 37.3 3.7e-39 134.4 25.9 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97382.1 - 1.5e-09 37.4 38.2 3.2e-09 36.3 26.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Pox_MCEL PF03291.11 KFO97383.1 - 2.8e-108 361.7 1.3 3.7e-108 361.3 0.9 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 KFO97383.1 - 4.4e-12 45.8 0.2 9.2e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO97383.1 - 1.1e-08 35.3 0.0 2.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO97383.1 - 2.4e-08 33.8 0.0 4.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO97383.1 - 3.1e-07 30.9 0.0 6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO97383.1 - 5.3e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO97383.1 - 5.8e-06 26.5 0.1 1.1e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFO97383.1 - 0.0039 16.8 0.1 0.0074 15.9 0.1 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 KFO97383.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KFO97383.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KFO97383.1 - 0.021 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 KFO97383.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1279 PF06916.8 KFO97384.1 - 1.2e-25 89.6 0.3 2.6e-25 88.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) LEA_4 PF02987.11 KFO97384.1 - 3.9e-05 23.4 11.6 3.9e-05 23.4 8.0 1.7 1 1 0 1 1 1 1 Late embryogenesis abundant protein Apolipoprotein PF01442.13 KFO97384.1 - 8.3e-05 22.1 0.8 0.00014 21.4 0.6 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.2 KFO97384.1 - 0.0018 18.6 9.5 0.0035 17.6 6.6 1.5 1 0 0 1 1 1 1 YtxH-like protein ISG65-75 PF11727.3 KFO97384.1 - 0.008 15.2 2.9 0.012 14.7 2.0 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Mit_KHE1 PF10173.4 KFO97384.1 - 0.015 15.1 0.4 0.026 14.4 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related AAA_28 PF13521.1 KFO97384.1 - 0.033 14.1 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.8 KFO97384.1 - 0.089 13.1 1.0 0.17 12.3 0.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CAAD PF14159.1 KFO97384.1 - 0.21 11.2 1.1 0.62 9.7 0.0 2.2 2 1 1 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Phasin PF05597.6 KFO97384.1 - 0.82 9.4 5.4 1.5 8.5 3.7 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Phe_tRNA-synt_N PF02912.13 KFO97384.1 - 0.98 9.1 5.0 3.6 7.3 3.5 1.8 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1664 PF07889.7 KFO97384.1 - 1.4 8.7 5.0 2.6 7.8 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CD34_antigen PF06365.7 KFO97385.1 - 0.013 15.1 1.3 0.023 14.3 0.9 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Shisa PF13908.1 KFO97385.1 - 0.031 14.4 0.9 0.031 14.4 0.6 2.2 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 KFO97385.1 - 0.043 13.5 0.8 0.11 12.1 0.2 1.8 2 0 0 2 2 2 0 TMEM154 protein family Lig_chan PF00060.21 KFO97385.1 - 0.068 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel m04gp34like PF12216.3 KFO97385.1 - 0.081 12.2 0.9 0.19 11.0 0.4 1.7 2 0 0 2 2 2 0 Immune evasion protein MYCBPAP PF14646.1 KFO97386.1 - 4e-07 29.1 0.0 0.021 13.5 0.0 3.6 3 0 0 3 3 3 3 MYCBP-associated protein family Motile_Sperm PF00635.21 KFO97386.1 - 4.7e-06 26.2 0.4 0.02 14.5 0.0 5.1 5 0 0 5 5 5 1 MSP (Major sperm protein) domain WD40 PF00400.27 KFO97389.1 - 3.1e-27 93.4 27.6 2.6e-07 30.2 1.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Y_phosphatase PF00102.22 KFO97390.1 - 1.7e-77 259.9 0.1 2e-77 259.7 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFO97390.1 - 0.0058 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAC2 PF09754.4 KFO97391.1 - 6.1e-38 130.8 0.0 8.2e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 PAC2 family CEP76-C2 PF15627.1 KFO97392.1 - 1.5e-54 183.7 0.0 2.5e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.14 KFO97392.1 - 0.008 16.3 0.1 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily TAF PF02969.12 KFO97392.1 - 0.04 13.8 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) WH2 PF02205.15 KFO97393.1 - 0.09 12.4 1.2 7.3 6.3 0.3 3.7 4 0 0 4 4 4 0 WH2 motif FYVE PF01363.16 KFO97393.1 - 0.43 10.4 14.4 1.1 9.1 10.0 1.7 1 1 0 1 1 1 0 FYVE zinc finger PRELI PF04707.9 KFO97394.1 - 3.9e-54 182.4 0.0 4.9e-54 182.1 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family PDGLE PF13190.1 KFO97394.1 - 0.032 13.8 0.1 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 PDGLE domain Peptidase_M41 PF01434.13 KFO97395.1 - 7.5e-74 247.7 0.1 1.1e-73 247.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFO97395.1 - 1.6e-42 144.8 0.0 3.3e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KFO97395.1 - 5e-10 39.5 0.1 2.1e-09 37.5 0.1 2.1 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 KFO97395.1 - 0.00015 21.8 0.1 0.009 16.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFO97395.1 - 0.00051 19.7 0.0 0.0023 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFO97395.1 - 0.00055 19.6 2.4 0.0053 16.4 0.7 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KFO97395.1 - 0.00079 20.2 0.0 0.003 18.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFO97395.1 - 0.0012 18.8 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 KFO97395.1 - 0.0014 17.7 0.1 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KFO97395.1 - 0.0034 17.2 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFO97395.1 - 0.0036 16.3 0.0 0.0096 14.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KFO97395.1 - 0.0049 15.6 0.0 0.0088 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KFO97395.1 - 0.011 15.7 0.4 0.14 12.1 0.0 2.5 2 1 1 3 3 2 0 AAA ATPase domain IstB_IS21 PF01695.12 KFO97395.1 - 0.013 14.8 0.2 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KFO97395.1 - 0.033 13.5 0.4 0.076 12.4 0.3 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KFO97395.1 - 0.074 12.1 0.3 0.23 10.6 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFO97395.1 - 0.075 13.3 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFO97395.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFO97395.1 - 0.12 12.2 0.5 0.35 10.7 0.0 2.1 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 KFO97395.1 - 0.15 11.3 0.4 0.37 9.9 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Tubulin PF00091.20 KFO97396.1 - 5.1e-71 238.9 0.0 8.1e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFO97396.1 - 5.7e-49 165.3 0.1 1e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFO97396.1 - 2.5e-06 27.5 0.0 7.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFO97396.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Endothelin PF00322.12 KFO97397.1 - 0.063 12.5 1.0 0.16 11.2 0.7 1.6 1 0 0 1 1 1 0 Endothelin family CIDE-N PF02017.10 KFO97398.1 - 7.5e-33 112.1 0.0 1.7e-32 111.0 0.0 1.6 2 0 0 2 2 2 1 CIDE-N domain FAD_binding_4 PF01565.18 KFO97398.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Inositol_P PF00459.20 KFO97399.1 - 1.3e-73 247.6 0.1 1.4e-73 247.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DivIC PF04977.10 KFO97401.1 - 0.0018 17.7 3.6 0.0018 17.7 2.5 3.0 2 2 1 3 3 3 1 Septum formation initiator TMF_DNA_bd PF12329.3 KFO97401.1 - 0.0026 17.5 27.3 0.017 14.9 4.7 2.7 3 1 0 3 3 2 2 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 KFO97401.1 - 0.003 17.2 12.2 0.057 13.1 1.3 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding BRX_N PF13713.1 KFO97401.1 - 0.017 14.5 1.0 0.035 13.5 0.2 2.0 2 0 0 2 2 1 0 Transcription factor BRX N-terminal domain RICH PF05062.7 KFO97401.1 - 0.034 14.2 14.8 0.46 10.6 3.4 2.4 2 0 0 2 2 2 0 RICH domain Serpin PF00079.15 KFO97401.1 - 0.047 12.8 0.2 0.084 12.0 0.2 1.3 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) Ax_dynein_light PF10211.4 KFO97401.1 - 0.11 12.2 16.3 0.11 12.2 2.1 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF4618 PF15397.1 KFO97401.1 - 0.15 11.3 10.4 1.4 8.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF3510 PF12022.3 KFO97401.1 - 0.17 12.0 2.1 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Filament PF00038.16 KFO97401.1 - 0.25 10.7 16.2 0.092 12.2 2.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein Nup54 PF13874.1 KFO97401.1 - 0.39 10.3 10.7 0.3 10.7 0.3 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2664 PF10867.3 KFO97401.1 - 0.5 11.0 4.7 0.36 11.4 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) CENP-F_leu_zip PF10473.4 KFO97401.1 - 0.69 9.7 18.0 1.3 8.8 3.7 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 KFO97401.1 - 0.71 9.6 5.2 5.6 6.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 KFO97401.1 - 1.2 9.5 10.2 3.4 8.1 0.3 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 KFO97401.1 - 1.3 8.5 21.7 1.5 8.3 4.9 2.1 1 1 1 2 2 2 0 IncA protein CDC37_N PF03234.9 KFO97401.1 - 1.4 9.2 11.8 1.4 9.2 5.4 2.0 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF4140 PF13600.1 KFO97401.1 - 1.5 9.2 10.1 2.4 8.6 0.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 KFO97401.1 - 1.8 7.5 19.1 2 7.4 3.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 YPEB PF14620.1 KFO97401.1 - 1.8 7.5 9.0 0.87 8.5 2.7 1.9 1 1 0 2 2 2 0 YpeB sporulation GAS PF13851.1 KFO97401.1 - 3.1 6.9 19.4 33 3.6 13.4 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.6 KFO97401.1 - 3.2 7.4 9.5 3.5 7.3 1.9 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.17 KFO97401.1 - 3.5 7.6 18.4 4.3 7.3 4.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nefa_Nip30_N PF10187.4 KFO97401.1 - 3.6 7.8 12.9 0.1 12.7 2.9 2.2 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 ADIP PF11559.3 KFO97401.1 - 4 7.3 19.0 5.9 6.7 3.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4047 PF13256.1 KFO97401.1 - 4.3 7.3 12.0 0.28 11.1 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Mod_r PF07200.8 KFO97401.1 - 5.3 6.9 16.0 2.5 7.9 3.0 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.7 KFO97401.1 - 5.3 6.7 17.6 2.7 7.7 2.3 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2205 PF10224.4 KFO97401.1 - 5.9 6.5 10.7 10 5.8 0.5 2.4 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Herpes_UL6 PF01763.11 KFO97401.1 - 6.1 4.8 11.5 0.39 8.8 2.0 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF4132 PF13569.1 KFO97401.1 - 6.8 6.1 7.2 0.97 8.9 1.3 2.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4132) DUF4200 PF13863.1 KFO97401.1 - 7.3 6.5 24.9 2.4 8.1 1.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 KFO97401.1 - 8.2 6.4 15.8 1.3 9.0 1.3 2.8 1 1 2 3 3 3 0 DivIVA protein Metallophos PF00149.23 KFO97402.1 - 1.5e-08 34.2 1.2 1.9e-07 30.6 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFO97402.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain G-alpha PF00503.15 KFO97403.1 - 4.8e-116 387.6 2.8 5.3e-116 387.5 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFO97403.1 - 4.2e-16 58.6 2.4 7e-13 48.1 0.3 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KFO97403.1 - 3.5e-05 24.2 0.6 0.1 13.1 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KFO97403.1 - 7.6e-05 21.9 2.5 0.0034 16.5 0.2 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFO97403.1 - 0.00011 21.7 0.2 0.016 14.6 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KFO97403.1 - 0.019 14.4 0.2 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFO97403.1 - 0.048 13.6 0.2 2.3 8.1 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2570 PF10828.3 KFO97403.1 - 0.22 11.1 2.1 0.62 9.6 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) PBP1_TM PF14812.1 KFO97404.1 - 0.044 14.0 5.4 1.3 9.4 0.1 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNAP PF14938.1 KFO97405.1 - 1.6e-28 99.6 13.3 2.2e-28 99.2 9.2 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 KFO97405.1 - 0.0001 21.8 15.1 0.052 13.2 1.4 4.8 1 1 4 5 5 5 4 TPR repeat TPR_14 PF13428.1 KFO97405.1 - 0.00058 20.2 13.9 2.1 9.2 0.5 6.3 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO97405.1 - 0.005 16.7 17.8 0.092 12.6 2.7 4.3 1 1 4 5 5 5 3 Tetratricopeptide repeat DUF2150 PF09920.4 KFO97405.1 - 0.12 11.9 0.8 0.38 10.3 0.1 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) TPR_5 PF12688.2 KFO97405.1 - 0.25 11.3 3.0 0.68 9.9 0.2 2.3 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_1 PF00515.23 KFO97405.1 - 0.49 10.0 13.8 14 5.4 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat NSF PF02071.15 KFO97405.1 - 0.76 10.5 18.3 1.1 10.1 0.3 5.9 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_2 PF07719.12 KFO97405.1 - 3.2 7.8 22.7 4.2 7.5 0.1 7.3 4 2 6 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97405.1 - 7.2 7.4 20.0 2.2 9.0 3.0 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat APCDDC PF14921.1 KFO97406.1 - 9.7e-125 414.6 3.0 1.8e-98 328.7 0.9 2.2 2 0 0 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 OMP_b-brl_2 PF13568.1 KFO97406.1 - 0.082 12.7 0.2 0.53 10.0 0.0 2.1 2 1 0 2 2 2 0 Outer membrane protein beta-barrel domain Motile_Sperm PF00635.21 KFO97407.1 - 4.4e-32 109.9 0.1 7e-32 109.3 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Ras PF00071.17 KFO97408.1 - 1.5e-47 161.0 0.0 1.7e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97408.1 - 5.5e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO97408.1 - 5.2e-07 29.0 0.0 7.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Cyt-b5 PF00173.23 KFO97408.1 - 0.046 13.5 0.1 2.7 7.8 0.0 2.4 1 1 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Sec16_C PF12931.2 KFO97408.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 HEAT PF02985.17 KFO97409.1 - 1.7e-24 83.6 19.7 0.00025 20.8 0.0 10.4 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.1 KFO97409.1 - 5.5e-16 58.6 3.0 3.5e-05 23.9 0.0 6.3 4 2 4 8 8 8 6 HEAT repeats AF1Q PF15017.1 KFO97409.1 - 1e-06 28.5 0.3 4.2e-06 26.5 0.2 2.1 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Cnd1 PF12717.2 KFO97409.1 - 0.017 15.0 0.8 3.9 7.2 0.1 3.8 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFO97409.1 - 0.048 14.1 4.9 1.6 9.3 0.0 5.2 5 1 1 6 6 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFO97409.1 - 0.15 12.4 7.5 6.5 7.2 0.1 5.3 5 2 0 5 5 5 0 Vacuolar 14 Fab1-binding region RhoGAP PF00620.22 KFO97410.1 - 1.8e-34 118.5 0.4 1.8e-34 118.5 0.3 3.6 2 2 1 3 3 3 2 RhoGAP domain DUF948 PF06103.6 KFO97410.1 - 1.5 8.7 8.2 0.24 11.3 1.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tsg PF04668.7 KFO97411.1 - 1.8e-56 189.9 6.5 1.8e-56 189.9 4.5 2.3 2 1 0 2 2 2 1 Twisted gastrulation (Tsg) protein conserved region Ank PF00023.25 KFO97412.1 - 4.3e-27 92.5 0.1 3.5e-08 32.8 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFO97412.1 - 6.9e-23 80.7 0.1 1.2e-15 57.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFO97412.1 - 1.8e-20 72.4 0.1 1.7e-09 37.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO97412.1 - 1.9e-17 61.6 0.0 0.00011 22.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFO97412.1 - 7.9e-15 54.9 0.0 1.2e-07 32.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) 2Fe-2S_thioredx PF01257.14 KFO97413.1 - 1.4e-66 222.5 0.1 1.6e-66 222.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 KFO97413.1 - 0.089 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) DUF3166 PF11365.3 KFO97414.1 - 2.6e-61 204.1 28.6 6.5e-42 141.9 1.5 5.3 4 1 1 5 5 5 3 Protein of unknown function (DUF3166) TSC22 PF01166.13 KFO97414.1 - 0.00068 19.5 44.3 0.0074 16.2 0.2 7.0 7 1 0 7 7 7 3 TSC-22/dip/bun family Fes1 PF08609.5 KFO97414.1 - 0.13 12.7 8.6 2.7 8.5 1.3 3.6 3 1 0 4 4 4 0 Nucleotide exchange factor Fes1 TPR_MLP1_2 PF07926.7 KFO97414.1 - 0.45 10.2 43.9 0.33 10.7 4.5 5.2 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 KFO97414.1 - 0.46 10.3 8.8 4.6 7.1 0.0 4.6 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Ras PF00071.17 KFO97415.1 - 5.6e-46 155.8 0.2 6.4e-46 155.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97415.1 - 3.4e-12 46.9 0.0 5.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO97415.1 - 9.2e-12 44.5 0.2 1.1e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO97415.1 - 2.1e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFO97415.1 - 0.00043 19.4 0.1 0.00045 19.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region YTH PF04146.10 KFO97415.1 - 0.034 13.7 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain Y_phosphatase PF00102.22 KFO97416.1 - 4.9e-154 510.4 0.1 2.1e-86 289.1 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFO97416.1 - 1.5e-25 89.1 13.6 1.1e-10 41.4 0.0 5.7 6 0 0 6 6 5 3 Fibronectin type III domain MAM PF00629.18 KFO97416.1 - 6.7e-25 87.7 0.0 3.7e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 MAM domain DSPc PF00782.15 KFO97416.1 - 3.7e-09 36.2 0.1 0.0019 17.7 0.0 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFO97416.1 - 3.3e-05 23.9 0.0 0.017 15.1 0.0 2.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFO97416.1 - 5e-05 23.6 0.0 0.036 14.3 0.0 2.8 2 0 0 2 2 2 1 Tyrosine phosphatase family ig PF00047.20 KFO97416.1 - 7.6e-05 22.7 0.1 0.00098 19.1 0.0 2.8 3 0 0 3 3 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFO97416.1 - 8.6e-05 22.5 0.0 0.00026 21.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO97416.1 - 0.00084 19.8 0.0 0.0062 17.0 0.0 2.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFO97416.1 - 0.00091 19.0 0.0 0.0026 17.5 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain PepSY_TM_3 PF13706.1 KFO97416.1 - 0.016 14.5 0.6 0.035 13.5 0.3 1.7 2 0 0 2 2 2 0 PepSY-associated TM helix TMEM154 PF15102.1 KFO97416.1 - 0.065 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DctM PF06808.7 KFO97416.1 - 0.074 11.5 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 DctM-like transporters LRR_4 PF12799.2 KFO97417.1 - 7.7e-29 98.8 53.9 2.4e-08 33.4 2.4 6.0 2 1 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO97417.1 - 2.2e-23 81.7 27.3 3.9e-09 36.1 4.9 4.5 2 2 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFO97417.1 - 1.3e-18 64.1 35.4 0.0092 15.8 0.4 9.3 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_7 PF13504.1 KFO97417.1 - 6e-12 43.7 26.8 0.03 14.4 0.1 9.3 9 0 0 9 9 9 5 Leucine rich repeat LRR_6 PF13516.1 KFO97417.1 - 0.00045 20.0 25.2 1.6 9.0 0.1 8.2 7 1 1 8 8 8 2 Leucine Rich repeat LRR_9 PF14580.1 KFO97417.1 - 0.036 13.6 7.9 0.21 11.1 1.0 2.4 1 1 2 3 3 3 0 Leucine-rich repeat DUF2371 PF10177.4 KFO97418.1 - 9e-59 197.3 0.0 1e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) Tetraspannin PF00335.15 KFO97418.1 - 0.0064 15.7 0.4 0.0093 15.2 0.3 1.2 1 0 0 1 1 1 1 Tetraspanin family MFS_1 PF07690.11 KFO97418.1 - 0.0074 15.0 0.0 0.0088 14.7 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF998 PF06197.8 KFO97418.1 - 0.035 13.3 0.7 0.63 9.3 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF998) DUF202 PF02656.10 KFO97418.1 - 0.046 13.9 0.0 3.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SKIP_SNW PF02731.10 KFO97418.1 - 0.071 12.5 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 SKIP/SNW domain TMEM171 PF15471.1 KFO97418.1 - 0.11 11.2 1.9 4.3 6.0 0.0 2.0 1 1 0 2 2 2 0 Transmembrane protein family 171 Neurensin PF14927.1 KFO97418.1 - 0.11 11.8 3.0 0.28 10.5 2.1 1.9 1 1 0 1 1 1 0 Neurensin Flavi_NS2B PF01002.14 KFO97418.1 - 0.12 11.9 0.6 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B AKAP7_NLS PF10469.4 KFO97419.1 - 1.9e-43 148.6 0.2 2.1e-43 148.4 0.2 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 KFO97419.1 - 5.1e-06 26.2 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KFO97419.1 - 0.023 14.6 0.1 2.4 8.1 0.0 2.6 2 1 0 2 2 2 0 LigT like Phosphoesterase 4_1_CTD PF05902.8 KFO97420.1 - 1.2e-56 189.6 13.4 1.2e-56 189.6 9.3 2.7 4 0 0 4 4 4 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 KFO97420.1 - 5.1e-26 90.1 3.2 1.5e-25 88.6 2.2 1.9 1 0 0 1 1 1 1 SAB domain FERM_N PF09379.5 KFO97420.1 - 1.6e-23 82.5 0.2 1.8e-22 79.2 0.0 2.7 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.5 KFO97420.1 - 7.5e-23 80.5 0.0 1.9e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFO97420.1 - 1.2e-20 73.9 0.0 1.2e-20 73.9 0.0 3.8 3 1 0 4 4 4 1 FERM central domain FA PF08736.6 KFO97420.1 - 1e-18 66.8 6.4 3.1e-18 65.2 4.4 1.9 1 0 0 1 1 1 1 FERM adjacent (FA) BTB PF00651.26 KFO97421.1 - 3e-28 98.0 0.9 5.7e-28 97.1 0.6 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFO97421.1 - 9.1e-25 85.4 37.6 1.8e-05 24.7 0.1 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO97421.1 - 2.2e-23 81.2 47.7 2.1e-06 27.7 2.6 6.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO97421.1 - 2.5e-19 68.1 27.6 0.0013 18.9 0.1 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO97421.1 - 3.2e-15 55.7 23.4 0.00093 19.2 0.2 5.8 6 0 0 6 6 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO97421.1 - 1.2e-13 50.7 21.5 0.0021 18.1 0.4 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type LIM PF00412.17 KFO97421.1 - 0.022 14.8 19.4 2.1 8.4 2.5 4.3 2 2 2 4 4 4 0 LIM domain zf-C2H2_6 PF13912.1 KFO97421.1 - 0.026 14.4 9.7 0.62 10.0 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger BTB_2 PF02214.17 KFO97421.1 - 0.05 13.7 0.3 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain zf-C2HC_2 PF13913.1 KFO97421.1 - 0.065 12.9 5.1 1.5 8.5 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_4 PF07975.7 KFO97421.1 - 0.56 10.2 20.4 4.6 7.3 2.3 4.2 3 1 1 4 4 3 0 TFIIH C1-like domain Elf1 PF05129.8 KFO97421.1 - 1.5 8.5 16.6 0.21 11.3 0.4 3.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 KFO97421.1 - 2 8.6 24.7 1.8 8.7 4.1 3.8 3 2 0 3 3 3 0 CHY zinc finger zf-trcl PF13451.1 KFO97421.1 - 3.3 7.4 12.7 38 4.0 0.1 4.9 5 0 0 5 5 5 0 Probable zinc-binding domain FYDLN_acid PF09538.5 KFO97421.1 - 6 7.5 18.0 34 5.0 0.0 4.9 3 2 1 4 4 4 0 Protein of unknown function (FYDLN_acid) AKAP7_RIRII_bdg PF10470.4 KFO97422.1 - 1e-05 25.2 2.4 1.1e-05 25.1 1.7 1.1 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein Psb28 PF03912.9 KFO97422.1 - 0.083 12.8 0.6 0.092 12.7 0.4 1.0 1 0 0 1 1 1 0 Psb28 protein GKAP PF03359.8 KFO97423.1 - 1.7e-132 442.3 6.6 1.7e-132 442.3 4.6 2.7 3 1 1 4 4 4 1 Guanylate-kinase-associated protein (GKAP) protein Homeobox_KN PF05920.6 KFO97424.1 - 0.002 17.7 1.8 0.0039 16.8 1.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain EF-hand_1 PF00036.27 KFO97425.1 - 3.9e-14 50.7 12.9 5.2e-08 31.6 1.1 4.7 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 KFO97425.1 - 2.8e-12 46.5 8.0 5e-07 29.7 0.6 3.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFO97425.1 - 8.1e-12 43.9 7.4 6.6e-08 31.8 0.6 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFO97425.1 - 1.5e-11 43.7 8.0 4.3e-05 23.0 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFO97425.1 - 4.3e-06 25.8 2.9 1.4e-05 24.1 0.9 2.6 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 KFO97425.1 - 0.00054 19.5 0.0 0.88 9.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 KFO97425.1 - 0.0034 17.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF1880 PF08976.6 KFO97425.1 - 0.041 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF2267 PF10025.4 KFO97425.1 - 0.075 13.0 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) SPARC_Ca_bdg PF10591.4 KFO97425.1 - 0.076 13.0 0.8 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.27 KFO97426.1 - 3.9e-14 50.7 12.9 5.2e-08 31.6 1.1 4.7 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 KFO97426.1 - 2.8e-12 46.5 8.0 5e-07 29.7 0.6 3.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFO97426.1 - 8.1e-12 43.9 7.4 6.6e-08 31.8 0.6 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFO97426.1 - 1.5e-11 43.7 8.0 4.3e-05 23.0 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFO97426.1 - 4.3e-06 25.8 2.9 1.4e-05 24.1 0.9 2.6 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 KFO97426.1 - 0.00054 19.5 0.0 0.88 9.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 KFO97426.1 - 0.0034 17.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain DUF1880 PF08976.6 KFO97426.1 - 0.041 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF2267 PF10025.4 KFO97426.1 - 0.075 13.0 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) SPARC_Ca_bdg PF10591.4 KFO97426.1 - 0.076 13.0 0.8 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region fn3 PF00041.16 KFO97427.1 - 5.6e-78 257.1 0.1 9.6e-15 54.4 0.0 5.8 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 KFO97427.1 - 3.8e-71 234.9 14.1 2.2e-20 72.2 0.1 7.7 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97427.1 - 1.3e-37 127.7 1.5 2.4e-10 40.3 0.0 7.0 8 0 0 8 8 8 5 Immunoglobulin domain Ig_3 PF13927.1 KFO97427.1 - 2.9e-20 72.4 6.4 0.00039 20.8 0.9 7.3 6 1 0 6 6 6 4 Immunoglobulin domain V-set PF07686.12 KFO97427.1 - 3.3e-19 68.8 15.7 0.00023 21.0 0.2 8.7 7 3 0 7 7 7 4 Immunoglobulin V-set domain ig PF00047.20 KFO97427.1 - 2.5e-10 40.3 11.3 0.077 13.1 0.0 7.2 6 1 0 6 6 6 3 Immunoglobulin domain C2-set_2 PF08205.7 KFO97427.1 - 5.6e-10 38.9 2.1 0.00088 19.1 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.12 KFO97427.1 - 8.4e-05 22.2 0.0 1.1 9.0 0.0 3.6 3 0 0 3 3 3 2 Tissue factor Herpes_gI PF01688.12 KFO97427.1 - 0.00075 18.6 0.0 2.3 7.3 0.0 3.7 4 0 0 4 4 4 1 Alphaherpesvirus glycoprotein I Herpes_gE PF02480.11 KFO97427.1 - 0.00089 17.6 0.1 0.092 10.9 0.0 3.2 3 0 0 3 3 3 1 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 KFO97427.1 - 0.0041 17.0 0.6 1.3 8.9 0.0 4.6 6 0 0 6 6 5 1 Natural killer cell receptor 2B4 LNS2 PF08235.8 KFO97428.1 - 9.2e-69 230.0 0.0 1.4e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KFO97428.1 - 3.5e-51 171.5 0.1 8.4e-51 170.3 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 KFO97428.1 - 3e-06 27.0 0.2 2.1e-05 24.3 0.2 2.5 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Tash_PEST PF07708.6 KFO97428.1 - 0.012 15.5 2.8 0.084 12.8 2.0 2.6 1 0 0 1 1 1 0 Tash protein PEST motif Hydrolase_3 PF08282.7 KFO97428.1 - 1.4 8.4 0.0 1.4 8.4 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase C1q PF00386.16 KFO97429.1 - 2.1e-17 63.3 0.3 1.6e-16 60.4 0.2 2.0 1 1 0 1 1 1 1 C1q domain Yae1_N PF09811.4 KFO97430.1 - 2.1e-09 36.7 29.2 0.077 12.5 18.1 3.5 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Sprouty PF05210.8 KFO97431.1 - 5.1e-37 126.2 34.6 8e-37 125.5 24.0 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) RRM_5 PF13893.1 KFO97432.1 - 3.2e-19 68.4 0.0 1.7e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO97432.1 - 5.4e-15 55.1 0.1 5.6e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO97432.1 - 3.9e-12 45.6 0.2 0.00012 21.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFO97432.1 - 8.5e-09 35.0 0.0 0.00026 20.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.12 KFO97432.1 - 1.1e-06 28.6 0.5 1.1e-06 28.6 0.3 1.9 2 0 0 2 2 2 1 PWI domain zf-CCCH PF00642.19 KFO97432.1 - 0.0019 17.8 2.5 0.0039 16.8 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 KFO97432.1 - 0.022 14.6 7.9 0.61 9.9 0.0 3.7 3 0 0 3 3 3 0 RNA binding motif RGS-like PF09128.6 KFO97432.1 - 0.037 13.5 0.1 0.037 13.5 0.1 2.8 2 1 0 2 2 2 0 Regulator of G protein signalling-like domain Nup35_RRM PF05172.8 KFO97432.1 - 0.13 12.0 0.1 24 4.7 0.0 2.9 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-RING_2 PF13639.1 KFO97433.1 - 6.7e-06 25.8 6.1 6.7e-06 25.8 4.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFO97433.1 - 5.5e-05 23.1 5.7 0.00029 20.7 4.0 2.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO97433.1 - 0.00037 20.1 4.5 0.0011 18.6 3.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 KFO97433.1 - 0.00069 19.0 3.7 0.0019 17.6 2.6 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.2 KFO97433.1 - 0.0011 19.0 5.5 0.0011 19.0 3.8 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger Mnd1 PF03962.10 KFO97433.1 - 0.002 17.8 6.6 0.002 17.8 4.6 3.2 3 0 0 3 3 3 2 Mnd1 family zf-C3HC4 PF00097.20 KFO97433.1 - 0.0041 16.7 6.2 0.0041 16.7 4.3 3.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO97433.1 - 0.0075 15.9 4.3 0.04 13.6 3.0 2.3 1 0 0 1 1 1 1 zinc-RING finger domain BRCA-2_OB3 PF09104.5 KFO97433.1 - 0.012 15.4 0.2 0.012 15.4 0.1 2.0 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 HrpB2 PF09487.5 KFO97433.1 - 0.16 12.1 4.9 0.37 10.9 0.4 3.0 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB2) PEP-utilisers_N PF05524.8 KFO97433.1 - 0.22 11.3 2.6 0.27 11.0 0.1 2.4 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal HALZ PF02183.13 KFO97433.1 - 0.27 11.0 15.7 0.11 12.2 1.0 3.5 3 0 0 3 3 2 0 Homeobox associated leucine zipper DivIC PF04977.10 KFO97433.1 - 0.95 8.9 14.4 0.83 9.1 0.3 3.6 3 0 0 3 3 3 0 Septum formation initiator DUF904 PF06005.7 KFO97433.1 - 1.7 8.9 33.4 0.051 13.8 4.1 4.3 3 1 0 4 4 4 0 Protein of unknown function (DUF904) zf-RING_4 PF14570.1 KFO97433.1 - 2.3 7.8 9.6 0.44 10.1 2.6 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain TSC22 PF01166.13 KFO97433.1 - 6.1 6.8 17.2 0.89 9.5 1.5 4.6 3 1 1 4 4 4 0 TSC-22/dip/bun family Microtub_assoc PF07989.6 KFO97433.1 - 9.1 6.1 16.6 0.2 11.4 0.5 4.3 3 1 0 4 4 4 0 Microtubule associated 7tm_1 PF00001.16 KFO97434.1 - 4e-42 144.1 11.5 5.5e-42 143.6 8.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97434.1 - 4.6e-10 39.0 11.9 1e-09 37.9 8.2 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO97434.1 - 3.7e-05 22.9 10.3 4.3e-05 22.7 5.1 2.2 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PHO4 PF01384.15 KFO97434.1 - 0.35 9.4 3.0 0.69 8.5 2.1 1.4 1 1 0 1 1 1 0 Phosphate transporter family Kelch_1 PF01344.20 KFO97435.1 - 1.6e-75 248.4 16.1 2.9e-15 55.5 0.2 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFO97435.1 - 3.1e-41 137.8 3.4 1.2e-07 31.6 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.10 KFO97435.1 - 5.4e-37 125.7 0.7 1.5e-36 124.3 0.5 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 KFO97435.1 - 2.3e-32 111.2 0.9 4.8e-32 110.2 0.6 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 KFO97435.1 - 4.3e-31 106.3 11.0 2.3e-06 27.5 0.1 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFO97435.1 - 5.9e-28 95.5 6.0 6.6e-05 22.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFO97435.1 - 2.3e-26 91.2 4.9 2.5e-05 23.9 0.0 6.2 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO97435.1 - 6.9e-08 32.2 13.7 0.43 10.5 0.2 5.4 5 0 0 5 5 5 4 Kelch motif Skp1_POZ PF03931.10 KFO97435.1 - 0.022 14.8 0.2 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Ashwin PF15323.1 KFO97435.1 - 0.033 14.2 0.6 0.033 14.2 0.4 1.9 2 0 0 2 2 2 0 Developmental protein PQQ_3 PF13570.1 KFO97435.1 - 2.1 8.7 12.0 25 5.3 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain 7tm_1 PF00001.16 KFO97436.1 - 9.1e-57 192.1 24.6 1.1e-56 191.8 17.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97436.1 - 1.2e-05 24.6 23.3 3.4e-05 23.1 16.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO97436.1 - 0.0003 19.9 20.6 0.0003 19.9 14.3 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UQ_con PF00179.21 KFO97436.1 - 0.073 12.5 0.8 0.22 10.9 0.2 1.9 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme I-set PF07679.11 KFO97437.1 - 3.6e-18 65.2 0.0 4.4e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97437.1 - 7.9e-08 32.3 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO97437.1 - 6.4e-06 26.5 0.0 0.00013 22.3 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO97437.1 - 4.6e-05 23.2 0.0 9.3e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFO97437.1 - 0.08 13.0 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFO97438.1 - 6.2e-40 134.9 0.0 3.4e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97438.1 - 1.5e-18 66.7 0.1 1.7e-08 34.4 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFO97438.1 - 7.9e-09 35.4 0.0 0.00018 21.3 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO97438.1 - 2.5e-08 34.3 1.0 0.0018 18.7 0.0 3.8 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFO97438.1 - 3.6e-07 30.2 0.0 0.035 14.2 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFO97438.1 - 0.0033 15.7 0.1 0.084 11.1 0.0 2.2 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E RhoGAP PF00620.22 KFO97439.1 - 3.2e-37 127.4 1.9 2.4e-36 124.6 0.0 2.8 3 0 0 3 3 3 1 RhoGAP domain Drc1-Sld2 PF11719.3 KFO97439.1 - 0.00021 20.5 28.6 0.0034 16.5 7.8 3.2 3 1 0 3 3 3 2 DNA replication and checkpoint protein Thymosin PF01290.15 KFO97440.1 - 2.7e-21 74.8 10.7 2.9e-21 74.7 7.4 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family WH2 PF02205.15 KFO97440.1 - 0.0012 18.3 0.1 0.0017 17.9 0.1 1.2 1 0 0 1 1 1 1 WH2 motif wnt PF00110.14 KFO97441.1 - 5.3e-105 351.0 26.5 6.2e-105 350.8 18.4 1.0 1 0 0 1 1 1 1 wnt family NDK PF00334.14 KFO97442.1 - 1.3e-38 131.8 0.0 1.7e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.8 KFO97442.1 - 3.7e-18 64.7 0.6 5.6e-18 64.1 0.4 1.3 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.17 KFO97443.1 - 2.3e-40 136.0 0.7 3.7e-19 68.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO97443.1 - 7.4e-31 105.9 0.1 2.8e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO97443.1 - 2.1e-08 33.8 0.1 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO97443.1 - 2.4e-06 27.3 0.1 0.082 12.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFO97443.1 - 7.1e-06 25.7 0.0 0.00045 19.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 KFO97443.1 - 0.00056 19.8 0.6 0.15 12.1 0.1 2.6 2 1 0 3 3 3 2 Nmi/IFP 35 domain (NID) Aminotran_3 PF00202.16 KFO97444.1 - 1.5e-77 260.7 0.0 1.8e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFO97444.1 - 0.0007 18.6 0.1 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3301 PF11743.3 KFO97444.1 - 0.046 13.2 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Reprolysin PF01421.14 KFO97445.1 - 2.3e-63 213.4 0.1 5.3e-63 212.2 0.1 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFO97445.1 - 4.1e-32 110.6 4.6 4.1e-32 110.6 3.2 3.5 4 1 0 4 4 2 1 ADAM cysteine-rich Reprolysin_5 PF13688.1 KFO97445.1 - 1.9e-24 86.6 2.2 4.5e-24 85.4 1.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.18 KFO97445.1 - 1.9e-23 82.4 25.6 1.9e-23 82.4 17.8 4.1 3 1 1 4 4 3 1 Disintegrin Pep_M12B_propep PF01562.14 KFO97445.1 - 6.4e-22 77.7 0.3 1.1e-21 77.0 0.2 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_3 PF13582.1 KFO97445.1 - 2.5e-19 70.0 0.3 5.6e-19 68.8 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFO97445.1 - 2.9e-16 60.0 1.0 6.3e-16 58.9 0.7 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFO97445.1 - 1.7e-14 53.8 0.6 2.8e-14 53.1 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFO97445.1 - 0.0014 18.7 14.3 0.0014 18.7 9.9 6.0 5 1 0 5 5 2 1 EGF-like domain Peptidase_M66 PF10462.4 KFO97445.1 - 0.025 13.4 0.3 0.04 12.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 KFO97445.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Matrixin PIG-P PF08510.7 KFO97445.1 - 0.2 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 PIG-P Mg_trans_NIPA PF05653.9 KFO97446.1 - 2.7e-129 430.4 14.6 3.3e-129 430.1 10.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFO97446.1 - 1.2e-09 38.3 0.6 1.2e-09 38.3 0.5 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFO97446.1 - 4.4e-07 29.9 4.8 4.4e-07 29.9 3.3 3.6 3 1 1 4 4 4 1 EamA-like transporter family K1 PF02960.9 KFO97446.1 - 0.93 9.5 8.6 1.3 9.0 3.8 2.6 2 1 1 3 3 3 0 K1 glycoprotein Pkinase_Tyr PF07714.12 KFO97447.1 - 1.5e-91 306.1 0.0 2.1e-91 305.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO97447.1 - 2e-49 168.0 0.0 4.2e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFO97447.1 - 2e-20 72.3 0.0 4.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFO97447.1 - 2.7e-16 58.6 0.3 5.7e-16 57.6 0.2 1.6 1 0 0 1 1 1 1 SH3 domain BTK PF00779.14 KFO97447.1 - 3.1e-14 52.2 3.4 5.5e-14 51.4 2.3 1.4 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.1 KFO97447.1 - 9.2e-14 50.7 0.3 2e-13 49.6 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFO97447.1 - 1.4e-11 44.4 0.6 4.1e-11 43.0 0.4 1.8 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 KFO97447.1 - 7.1e-10 38.2 0.0 1.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFO97447.1 - 8.2e-05 22.7 0.1 0.0002 21.4 0.1 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain PH_8 PF15409.1 KFO97447.1 - 0.00052 20.0 0.2 0.0019 18.2 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 KFO97447.1 - 0.021 13.7 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Med7 PF05983.6 KFO97448.1 - 8.7e-49 165.4 4.4 1.1e-48 165.0 3.0 1.1 1 0 0 1 1 1 1 MED7 protein Katanin_con80 PF13925.1 KFO97448.1 - 0.0025 17.5 1.0 0.0037 17.0 0.7 1.2 1 0 0 1 1 1 1 con80 domain of Katanin V-set PF07686.12 KFO97449.1 - 2.7e-13 49.8 0.7 2.7e-13 49.8 0.5 2.1 2 1 1 3 3 3 1 Immunoglobulin V-set domain I-set PF07679.11 KFO97449.1 - 0.00011 22.0 0.1 0.00029 20.6 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97449.1 - 0.00029 20.8 3.1 0.0015 18.6 2.2 2.2 1 1 0 1 1 1 1 Immunoglobulin domain V-set_CD47 PF08204.6 KFO97449.1 - 0.009 15.7 0.3 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain ig PF00047.20 KFO97449.1 - 0.014 15.4 0.2 0.014 15.4 0.2 2.7 2 2 0 2 2 2 0 Immunoglobulin domain DUF3309 PF11752.3 KFO97449.1 - 0.034 13.9 0.3 0.059 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Receptor_2B4 PF11465.3 KFO97449.1 - 0.042 13.7 0.2 0.14 12.0 0.0 2.0 2 1 0 2 2 2 0 Natural killer cell receptor 2B4 Herpes_gI PF01688.12 KFO97449.1 - 0.055 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I MIF4G PF02854.14 KFO97450.1 - 5.2e-27 94.6 5.8 8.3e-27 93.9 4.0 1.3 1 0 0 1 1 1 1 MIF4G domain BP28CT PF08146.7 KFO97450.1 - 0.017 14.8 0.1 0.05 13.3 0.0 1.8 1 1 0 1 1 1 0 BP28CT (NUC211) domain Cauli_AT PF03233.8 KFO97450.1 - 6.1 6.5 10.8 0.12 12.0 2.4 1.8 2 0 0 2 2 2 0 Aphid transmission protein MH2 PF03166.9 KFO97451.1 - 1.3e-62 210.8 0.1 1.5e-62 210.6 0.1 1.0 1 0 0 1 1 1 1 MH2 domain Dymeclin PF09742.4 KFO97452.1 - 1e-11 43.7 1.5 1.1e-11 43.6 1.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein PGG PF13962.1 KFO97452.1 - 0.12 11.9 0.2 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function PAP_assoc PF03828.14 KFO97454.1 - 1.9e-28 98.1 0.2 1.1e-14 54.1 0.2 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase zf-CCHC PF00098.18 KFO97454.1 - 1.7e-15 56.0 22.3 2.7e-05 23.8 2.3 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 KFO97454.1 - 2.1e-07 30.3 17.4 0.0057 16.1 0.7 4.7 4 0 0 4 4 4 3 Zinc knuckle NTP_transf_2 PF01909.18 KFO97454.1 - 2.3e-06 27.8 0.0 0.0008 19.6 0.0 3.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.6 KFO97454.1 - 0.00024 20.9 0.0 1.2 9.0 0.0 2.9 2 0 0 2 2 2 2 tRNA nucleotidyltransferase, second domain zf-CCHC_4 PF14392.1 KFO97454.1 - 0.00034 20.2 19.0 0.011 15.3 1.1 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-C2H2_jaz PF12171.3 KFO97454.1 - 0.0057 16.7 3.0 0.031 14.4 2.1 2.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Fe-S_biosyn PF01521.15 KFO97455.1 - 1e-18 67.3 0.0 1.1e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Sad1_UNC PF07738.8 KFO97456.1 - 8.1e-32 109.8 0.0 8.9e-32 109.7 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal IncA PF04156.9 KFO97457.1 - 0.00024 20.7 8.6 0.00024 20.7 6.0 2.3 2 0 0 2 2 2 1 IncA protein Peptidase_M14 PF00246.19 KFO97458.1 - 2.9e-26 92.6 0.0 9.4e-26 91.0 0.0 1.8 1 1 1 2 2 2 1 Zinc carboxypeptidase V-ATPase_H_N PF03224.9 KFO97458.1 - 0.0034 16.5 3.0 0.0049 16.0 0.0 2.5 3 1 0 3 3 3 1 V-ATPase subunit H AstE_AspA PF04952.9 KFO97458.1 - 0.017 13.9 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Sad1_UNC PF07738.8 KFO97459.1 - 1e-29 103.0 0.0 1.1e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SNF2_N PF00176.18 KFO97460.1 - 1.2e-72 244.2 0.9 3.1e-72 242.9 0.6 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 KFO97460.1 - 2.7e-33 114.1 1.1 2.7e-33 114.1 0.8 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 KFO97460.1 - 1.4e-27 95.1 14.1 1.2e-17 63.2 0.0 4.3 5 0 0 5 5 5 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFO97460.1 - 2.2e-14 53.0 0.0 5.1e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVT_1 PF00078.22 KFO97461.1 - 4.8e-18 65.2 0.0 8.3e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TetR_C_4 PF08359.6 KFO97462.1 - 0.02 14.7 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region Dynamin_N PF00350.18 KFO97464.1 - 3.6e-16 59.4 0.1 3.6e-16 59.4 0.1 2.7 2 2 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KFO97464.1 - 5.4e-07 29.5 0.1 0.00026 20.8 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFO97464.1 - 0.00071 19.0 0.7 1.1 8.5 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFO97464.1 - 0.0027 16.8 0.0 0.027 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KFO97464.1 - 0.0035 17.6 3.3 0.0038 17.5 0.0 2.4 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 KFO97464.1 - 0.0057 17.1 0.7 0.025 15.0 0.0 2.4 3 1 1 4 4 3 1 Miro-like protein AAA_29 PF13555.1 KFO97464.1 - 0.011 15.2 0.1 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 KFO97464.1 - 0.012 14.6 0.1 0.038 12.9 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain AAA_10 PF12846.2 KFO97464.1 - 0.017 14.5 2.9 0.13 11.6 0.1 2.9 3 0 0 3 3 3 0 AAA-like domain DUF87 PF01935.12 KFO97464.1 - 0.018 14.8 0.2 0.018 14.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 cobW PF02492.14 KFO97464.1 - 0.019 14.4 0.6 0.088 12.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 KFO97464.1 - 0.048 12.7 3.4 0.23 10.5 0.2 2.8 2 1 0 2 2 2 0 AIG1 family FtsK_SpoIIIE PF01580.13 KFO97464.1 - 0.071 12.5 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KFO97464.1 - 0.076 13.3 4.4 0.59 10.4 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 KFO97464.1 - 0.19 12.5 3.4 0.43 11.4 0.1 2.8 2 2 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 KFO97466.1 - 2.4e-33 115.9 1.5 4.4e-33 115.0 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO97466.1 - 3.7e-28 98.6 0.0 6.8e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFO97466.1 - 1.9e-13 50.3 0.0 5.7e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFO97466.1 - 0.00047 19.9 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase HAD_2 PF13419.1 KFO97466.1 - 0.0087 16.2 0.0 0.83 9.8 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Ndr PF03096.9 KFO97466.1 - 0.086 11.3 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family Neur_chan_memb PF02932.11 KFO97467.1 - 6e-81 271.8 15.1 1.2e-57 195.5 8.5 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFO97467.1 - 9.6e-77 256.9 4.3 1.2e-76 256.6 3.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Pkinase_Tyr PF07714.12 KFO97468.1 - 9.3e-91 303.4 0.0 1.8e-90 302.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Focal_AT PF03623.8 KFO97468.1 - 1.3e-47 160.7 0.0 2.4e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Focal adhesion targeting region Pkinase PF00069.20 KFO97468.1 - 3.1e-44 151.0 0.0 6.4e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain FERM_M PF00373.13 KFO97468.1 - 4.6e-11 42.9 3.6 1.5e-10 41.2 2.5 1.8 1 0 0 1 1 1 1 FERM central domain HEAT PF02985.17 KFO97469.1 - 1.1e-18 65.5 6.0 4.2e-05 23.2 0.0 9.3 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 KFO97469.1 - 5.6e-17 61.6 1.2 1.1e-08 35.3 0.0 7.5 7 2 2 9 9 9 3 HEAT-like repeat HEAT_2 PF13646.1 KFO97469.1 - 3.3e-15 56.1 0.8 1.2e-05 25.5 0.0 6.0 3 1 5 9 9 9 6 HEAT repeats IBN_N PF03810.14 KFO97469.1 - 1.1e-12 47.6 0.4 1.4e-11 44.1 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 KFO97469.1 - 1.1e-09 37.7 4.6 0.0016 18.1 0.0 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KFO97469.1 - 3e-05 23.4 3.6 0.39 10.0 0.0 4.4 3 1 1 4 4 4 2 CLASP N terminal UME PF08064.8 KFO97469.1 - 0.049 13.5 3.4 5 7.1 0.0 4.6 4 1 0 4 4 4 0 UME (NUC010) domain RIX1 PF08167.7 KFO97469.1 - 0.27 10.8 3.2 36 3.9 0.0 4.5 4 2 0 4 4 4 0 rRNA processing/ribosome biogenesis Peptidase_M1 PF01433.15 KFO97470.1 - 4.6e-140 467.1 0.0 6.2e-140 466.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFO97470.1 - 2.7e-65 220.7 0.0 5.5e-65 219.7 0.0 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFO97470.1 - 8.4e-23 80.8 0.3 1.8e-22 79.7 0.2 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily tRNA_anti-codon PF01336.20 KFO97470.1 - 0.098 12.5 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain NatB_MDM20 PF09797.4 KFO97470.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Tim44 PF04280.10 KFO97471.1 - 5.3e-27 94.6 0.0 6.8e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain ChaB PF06150.7 KFO97471.1 - 0.0079 15.9 1.0 0.022 14.5 0.1 2.1 2 0 0 2 2 2 1 ChaB MBA1 PF07961.6 KFO97471.1 - 0.046 12.5 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein Kri1 PF05178.7 KFO97471.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 KRI1-like family TTSSLRR PF12468.3 KFO97471.1 - 0.76 9.3 3.4 1.6 8.2 2.3 1.6 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein 7tm_3 PF00003.17 KFO97472.1 - 3.3e-16 59.3 9.6 1.3e-15 57.4 6.6 1.9 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR RhoGAP PF00620.22 KFO97473.1 - 3.9e-24 85.0 0.0 4.6e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain Rad60-SLD PF11976.3 KFO97474.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Proteasome PF00227.21 KFO97475.1 - 1.3e-32 112.6 0.0 1.4e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PIP5K PF01504.13 KFO97476.1 - 4.4e-75 252.0 0.1 5.3e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CWC25 PF12542.3 KFO97477.1 - 2.4e-20 72.7 0.1 2.4e-20 72.7 0.1 4.2 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KFO97477.1 - 2.7e-15 56.0 13.5 2.7e-15 56.0 9.4 6.0 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR tRNA-synt_1c PF00749.16 KFO97477.1 - 0.00021 20.0 4.2 0.00021 20.0 2.9 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_L14 PF00238.14 KFO97478.1 - 3e-35 120.6 0.1 3.3e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SH3_9 PF14604.1 KFO97479.1 - 1.4e-15 56.5 0.1 2.2e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFO97479.1 - 3.9e-13 48.5 0.1 6.5e-13 47.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFO97479.1 - 4.8e-08 32.3 0.0 1.3e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain LIM PF00412.17 KFO97479.1 - 8.9e-08 32.0 7.6 1.4e-07 31.4 5.3 1.3 1 0 0 1 1 1 1 LIM domain Nebulin PF00880.13 KFO97479.1 - 0.00054 19.4 0.5 0.11 12.1 0.1 2.7 2 0 0 2 2 2 2 Nebulin repeat Ribosomal_L19e PF01280.15 KFO97481.1 - 4.1e-63 211.5 14.3 4.1e-63 211.5 9.9 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e LRR_6 PF13516.1 KFO97482.1 - 2e-22 76.6 29.6 0.0047 16.8 0.0 11.3 11 1 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 KFO97482.1 - 1.5e-15 56.3 13.4 0.014 14.9 0.4 6.6 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO97482.1 - 4e-13 48.9 19.2 0.00016 21.3 2.7 5.9 3 3 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 KFO97482.1 - 4.2e-12 44.3 22.8 1.2 9.4 0.1 11.7 11 1 0 11 11 11 3 Leucine Rich Repeat LRR_7 PF13504.1 KFO97482.1 - 2e-07 30.0 21.1 0.85 10.0 0.0 10.5 11 0 0 11 11 11 2 Leucine rich repeat Med1 PF10744.4 KFO97483.1 - 2.6e-103 345.8 0.4 1e-102 343.8 0.0 2.1 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.20 KFO97484.1 - 4.8e-72 242.2 0.3 1.4e-71 240.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97484.1 - 3.5e-34 118.0 0.0 6.7e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO97484.1 - 0.00032 19.7 0.0 0.009 15.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFO97484.1 - 0.014 14.5 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HLH PF00010.21 KFO97485.1 - 1.8e-17 62.7 1.9 1.8e-17 62.7 1.3 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain LRR_4 PF12799.2 KFO97485.1 - 0.12 12.0 0.1 0.35 10.5 0.1 1.8 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) MENTAL PF10457.4 KFO97486.1 - 4.9e-74 247.6 8.8 5.4e-74 247.4 6.1 1.0 1 0 0 1 1 1 1 Cholesterol-capturing domain Per1 PF04080.8 KFO97487.1 - 9.7e-45 153.0 9.9 4.9e-27 95.0 0.6 2.0 2 0 0 2 2 2 2 Per1-like Pkinase_Tyr PF07714.12 KFO97488.1 - 2e-87 292.5 0.0 4e-87 291.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Recep_L_domain PF01030.19 KFO97488.1 - 1.3e-49 166.8 0.0 7.9e-30 103.1 0.0 2.7 2 1 0 2 2 2 2 Receptor L domain Pkinase PF00069.20 KFO97488.1 - 3.7e-41 141.0 0.0 6e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GF_recep_IV PF14843.1 KFO97488.1 - 2.3e-27 95.1 63.7 4.2e-25 87.8 10.7 4.4 2 1 1 3 3 3 3 Growth factor receptor domain IV Furin-like PF00757.15 KFO97488.1 - 6.7e-27 93.9 71.3 4.8e-26 91.2 27.4 3.2 2 1 0 2 2 2 1 Furin-like cysteine rich region Protocadherin PF08374.6 KFO97488.1 - 0.00049 19.8 0.1 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.1 KFO97488.1 - 0.0023 18.2 0.2 0.0052 17.1 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain APH PF01636.18 KFO97488.1 - 0.0031 17.3 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1191 PF06697.7 KFO97488.1 - 0.011 14.5 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 KFO97488.1 - 0.015 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rdx PF10262.4 KFO97489.1 - 3.5e-17 62.1 0.0 4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Rdx family SH2 PF00017.19 KFO97490.1 - 5.5e-16 58.1 0.0 1.1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain RA PF00788.18 KFO97490.1 - 2.3e-15 56.8 0.0 7e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFO97490.1 - 4.8e-08 33.1 0.1 1.3e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 PH domain adh_short PF00106.20 KFO97491.1 - 1.2e-29 103.3 0.5 1.7e-29 102.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFO97491.1 - 3.4e-12 46.3 0.3 4.8e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFO97491.1 - 4e-07 30.0 0.0 4.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFO97491.1 - 0.0033 17.4 0.1 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFO97491.1 - 0.014 15.1 0.1 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-H2C2_2 PF13465.1 KFO97492.1 - 2.5e-24 84.3 35.7 1.3e-07 31.5 0.6 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFO97492.1 - 1.3e-15 56.6 41.9 1.5e-05 25.0 0.3 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO97492.1 - 1.8e-09 37.2 40.5 0.00036 20.6 0.2 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFO97492.1 - 0.0039 17.3 31.0 0.19 12.0 1.8 5.9 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-MYND PF01753.13 KFO97492.1 - 0.041 13.7 0.5 0.041 13.7 0.3 4.0 4 1 0 4 4 4 0 MYND finger GAGA PF09237.6 KFO97492.1 - 0.056 13.0 2.6 0.08 12.5 0.1 2.4 1 1 0 2 2 2 0 GAGA factor C1_1 PF00130.17 KFO97492.1 - 0.057 13.1 23.1 0.42 10.3 1.2 3.9 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.3 KFO97492.1 - 0.2 11.8 28.5 0.26 11.4 0.2 6.2 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO97492.1 - 0.3 11.0 38.8 0.89 9.5 1.0 7.0 6 2 0 6 6 6 0 C2H2-type zinc finger AKAP95 PF04988.7 KFO97492.1 - 2 8.1 7.9 2.4 7.8 0.3 2.6 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-TRAF PF02176.13 KFO97492.1 - 2.5 8.5 15.4 3.8 7.9 2.8 3.6 2 1 2 4 4 4 0 TRAF-type zinc finger Sp38 PF07354.7 KFO97493.1 - 3.7e-120 399.6 7.9 4.2e-120 399.4 5.5 1.0 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) LRR_8 PF13855.1 KFO97494.1 - 2.6e-16 59.0 6.6 2e-10 40.2 0.0 3.2 2 2 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KFO97494.1 - 4.4e-09 35.1 13.0 0.0035 17.1 0.4 6.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 KFO97494.1 - 1e-06 28.2 7.2 0.0023 17.5 0.1 3.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF3700 PF12481.3 KFO97494.1 - 0.00029 20.1 0.1 0.00076 18.7 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein LRR_5 PF13306.1 KFO97494.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRRNT PF01462.13 KFO97494.1 - 0.0063 15.9 0.6 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFO97494.1 - 0.12 12.5 7.4 16 5.9 1.9 4.1 1 1 1 2 2 2 0 Leucine Rich repeat LRR_7 PF13504.1 KFO97494.1 - 0.18 12.1 14.9 1.9 9.0 0.1 5.8 6 1 0 6 6 6 0 Leucine rich repeat ORMDL PF04061.9 KFO97495.1 - 6e-53 178.0 4.8 6.8e-53 177.8 3.3 1.0 1 0 0 1 1 1 1 ORMDL family 7tm_3 PF00003.17 KFO97495.1 - 0.023 14.0 2.4 0.024 14.0 0.2 1.8 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Hormone_recep PF00104.25 KFO97496.1 - 3.4e-19 68.7 0.0 3.8e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Btz PF09405.5 KFO97497.1 - 6.6e-26 90.8 6.6 6.6e-26 90.8 4.6 2.6 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Cdc6_C PF09079.6 KFO97498.1 - 5.8e-14 51.5 0.8 1.1e-13 50.6 0.5 1.5 1 0 0 1 1 1 1 CDC6, C terminal AAA_22 PF13401.1 KFO97498.1 - 1.7e-12 47.5 0.0 4.3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFO97498.1 - 2.7e-09 37.2 2.6 7.1e-05 22.8 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.24 KFO97498.1 - 3.3e-08 33.7 0.0 5.5e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KFO97498.1 - 4.7e-05 23.1 0.1 9.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KFO97498.1 - 0.0024 17.5 0.1 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain DUF2277 PF10041.4 KFO97498.1 - 0.0048 16.8 0.1 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2277) DUF2075 PF09848.4 KFO97498.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KFO97498.1 - 0.03 13.8 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Hormone_recep PF00104.25 KFO97499.1 - 1.2e-19 70.2 0.1 1.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DNA_topoisoIV PF00521.15 KFO97500.1 - 1.3e-132 442.6 0.4 2.6e-132 441.6 0.0 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KFO97500.1 - 8.1e-36 122.8 1.7 2.1e-35 121.4 1.2 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KFO97500.1 - 1.1e-14 54.2 1.0 2.4e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KFO97500.1 - 1.1e-10 41.2 0.0 3.1e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thyroglobulin_1 PF00086.13 KFO97501.1 - 4.4e-21 74.0 0.7 4.4e-21 74.0 0.5 1.8 2 1 1 3 3 3 1 Thyroglobulin type-1 repeat PTB PF08416.8 KFO97502.1 - 1.2e-26 93.1 0.0 2.2e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.19 KFO97502.1 - 1.4e-10 40.8 0.0 2.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain HMG_box PF00505.14 KFO97503.1 - 2.8e-18 65.9 1.6 2.8e-18 65.9 1.1 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO97503.1 - 1.2e-06 28.7 0.6 1.2e-06 28.7 0.4 2.4 2 0 0 2 2 2 1 HMG-box domain Zip PF02535.17 KFO97503.1 - 6.9 5.5 5.9 10 5.0 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Filament PF00038.16 KFO97504.1 - 4.3e-28 98.7 24.9 6.6e-28 98.0 17.2 1.3 1 0 0 1 1 1 1 Intermediate filament protein BCAS2 PF05700.6 KFO97504.1 - 0.019 14.4 9.3 0.018 14.5 5.3 1.6 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Poty_PP PF08440.5 KFO97504.1 - 0.028 13.5 2.5 0.032 13.3 0.9 1.7 1 1 1 2 2 2 0 Potyviridae polyprotein Stonin2_N PF12016.3 KFO97504.1 - 0.042 13.0 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Stonin 2 DUF1664 PF07889.7 KFO97504.1 - 0.05 13.3 3.7 0.082 12.7 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.7 KFO97504.1 - 0.072 11.5 5.8 0.088 11.2 4.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Allexi_40kDa PF05549.6 KFO97504.1 - 0.3 10.3 3.2 0.39 9.9 1.2 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein V_ATPase_I PF01496.14 KFO97504.1 - 0.59 7.9 12.2 0.79 7.5 8.3 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 KFO97504.1 - 0.75 8.9 9.7 1.1 8.4 6.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit SYCE1 PF15233.1 KFO97504.1 - 0.93 9.4 19.2 1.3 8.9 12.4 2.2 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF4140 PF13600.1 KFO97504.1 - 3.4 8.1 10.5 1 9.8 2.1 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG2 PF06148.6 KFO97504.1 - 3.8 7.3 9.1 94 2.8 6.3 2.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AATF-Che1 PF13339.1 KFO97504.1 - 4.1 7.5 14.7 2 8.5 1.9 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor TPR_MLP1_2 PF07926.7 KFO97504.1 - 9.2 6.0 20.8 0.31 10.7 4.0 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 KFO97505.1 - 9.8e-100 334.0 21.0 1.8e-72 244.4 2.6 2.0 1 1 1 2 2 2 2 Intermediate filament protein Myosin_tail_1 PF01576.14 KFO97505.1 - 0.0013 16.6 1.4 0.0013 16.6 1.0 2.7 3 0 0 3 3 3 1 Myosin tail TPR_MLP1_2 PF07926.7 KFO97505.1 - 0.005 16.5 0.5 0.005 16.5 0.3 3.9 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein FlxA PF14282.1 KFO97505.1 - 0.0066 16.3 11.8 0.6 10.0 4.1 3.1 3 0 0 3 3 3 2 FlxA-like protein Racemase_4 PF13615.1 KFO97505.1 - 0.11 12.7 0.1 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Putative alanine racemase SlyX PF04102.7 KFO97505.1 - 0.13 12.6 11.6 24 5.3 0.1 3.6 3 0 0 3 3 3 0 SlyX DivIC PF04977.10 KFO97505.1 - 0.15 11.5 25.0 1 8.9 1.5 5.0 5 0 0 5 5 5 0 Septum formation initiator Prefoldin_2 PF01920.15 KFO97505.1 - 0.66 9.7 18.6 1 9.1 0.0 4.3 3 2 1 4 4 4 0 Prefoldin subunit DUF972 PF06156.8 KFO97505.1 - 1.7 9.0 16.2 1.5 9.2 1.2 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 KFO97505.1 - 4.2 7.3 5.9 8.5 6.3 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Filament PF00038.16 KFO97506.1 - 4.7e-99 331.7 39.3 5.4e-99 331.6 27.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Prefoldin_2 PF01920.15 KFO97506.1 - 0.1 12.3 0.3 0.1 12.3 0.2 5.2 3 2 1 4 4 4 0 Prefoldin subunit DUF573 PF04504.9 KFO97506.1 - 0.24 11.6 5.9 0.098 12.9 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF573 PRP1_N PF06424.7 KFO97506.1 - 1 9.6 10.3 0.18 12.1 3.8 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal PKI PF02827.11 KFO97506.1 - 1.4 9.0 5.2 1.5 8.9 1.0 2.8 2 1 1 3 3 3 0 cAMP-dependent protein kinase inhibitor Myosin_tail_1 PF01576.14 KFO97506.1 - 1.6 6.3 38.7 0.18 9.5 8.2 2.4 1 1 1 2 2 2 0 Myosin tail Ded_cyto PF06920.8 KFO97506.1 - 3 7.1 16.4 0.4 9.9 6.6 2.6 3 0 0 3 3 3 0 Dedicator of cytokinesis Mitofilin PF09731.4 KFO97506.1 - 5.3 5.5 34.0 0.27 9.8 16.2 1.9 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Filament PF00038.16 KFO97507.1 - 3.1e-61 207.5 25.9 3.4e-61 207.4 18.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF4296 PF14129.1 KFO97507.1 - 0.0043 17.1 2.5 0.014 15.5 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4296) DUF3510 PF12022.3 KFO97507.1 - 0.039 14.0 2.6 0.061 13.4 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) DUF3907 PF13047.1 KFO97507.1 - 0.053 13.1 2.9 1.5 8.4 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3907) BRAP2 PF07576.7 KFO97507.1 - 0.055 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 GLE1 PF07817.8 KFO97507.1 - 0.19 10.6 4.1 0.19 10.6 2.1 1.6 1 1 0 1 1 1 0 GLE1-like protein ADIP PF11559.3 KFO97507.1 - 0.31 10.9 19.0 0.064 13.1 7.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KFO97507.1 - 0.7 10.3 11.5 1.2 9.6 0.5 3.6 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF3508 PF12018.3 KFO97507.1 - 0.73 8.7 9.1 0.9 8.4 5.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) OmpH PF03938.9 KFO97507.1 - 0.89 9.4 18.1 13 5.7 12.4 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Tweety PF04906.8 KFO97507.1 - 1.1 7.5 5.0 1.2 7.4 2.6 1.6 1 1 1 2 2 2 0 Tweety IncA PF04156.9 KFO97507.1 - 2.2 7.8 21.8 14 5.1 7.2 2.5 1 1 1 2 2 2 0 IncA protein Striatin PF08232.7 KFO97507.1 - 5.2 7.3 15.9 3 8.1 2.9 2.3 2 0 0 2 2 2 0 Striatin family CENP-Q PF13094.1 KFO97507.1 - 7.2 6.6 18.2 3.7 7.5 5.0 2.8 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 KFO97507.1 - 7.5 4.2 18.3 5.6 4.6 3.2 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 KFO97507.1 - 8.3 6.2 10.0 12 5.7 2.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YgaB PF14182.1 KFO97507.1 - 8.5 6.6 14.6 1.2 9.4 5.0 3.0 2 2 1 3 3 3 0 YgaB-like protein Filament PF00038.16 KFO97508.1 - 1.8e-115 385.7 33.9 2e-115 385.5 23.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFO97508.1 - 0.00016 21.4 2.3 0.00016 21.4 1.6 3.3 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein DUF4618 PF15397.1 KFO97508.1 - 0.003 16.9 9.2 0.003 16.9 6.4 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4618) Myosin_tail_1 PF01576.14 KFO97508.1 - 0.0058 14.4 31.0 0.0048 14.7 6.4 2.9 1 1 1 2 2 2 1 Myosin tail ISAV_HA PF06215.6 KFO97508.1 - 0.0065 14.8 0.0 0.0092 14.3 0.0 1.1 1 0 0 1 1 1 1 Infectious salmon anaemia virus haemagglutinin FlaC_arch PF05377.6 KFO97508.1 - 0.0094 15.8 0.9 0.0094 15.8 0.6 4.4 5 0 0 5 5 3 1 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 KFO97508.1 - 0.014 15.1 1.7 0.014 15.1 1.2 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DivIC PF04977.10 KFO97508.1 - 0.015 14.7 25.3 0.17 11.3 1.4 4.8 5 0 0 5 5 5 0 Septum formation initiator Transposase_22 PF02994.9 KFO97508.1 - 0.059 11.8 19.1 0.061 11.8 7.3 2.3 1 1 1 2 2 2 0 L1 transposable element Vac_Fusion PF02346.11 KFO97508.1 - 0.18 11.2 2.6 8.8 5.8 0.4 3.0 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF4407 PF14362.1 KFO97508.1 - 0.2 10.5 13.5 0.48 9.3 4.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) ADIP PF11559.3 KFO97508.1 - 0.42 10.4 25.2 0.73 9.7 1.0 4.3 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 KFO97508.1 - 0.79 9.8 18.7 0.81 9.8 1.2 3.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KFO97508.1 - 1.1 8.8 36.7 0.7 9.4 10.8 3.9 2 2 2 4 4 4 0 IncA protein Prefoldin PF02996.12 KFO97508.1 - 1.2 8.7 16.3 4.4 6.9 1.2 4.2 4 1 0 4 4 4 0 Prefoldin subunit Baculo_PEP_C PF04513.7 KFO97508.1 - 1.4 8.7 17.1 4.3 7.1 0.5 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 KFO97508.1 - 3.5 7.6 20.6 2.2 8.2 0.1 3.5 3 1 1 4 4 4 0 FlxA-like protein Bap31 PF05529.7 KFO97508.1 - 4.9 6.5 12.1 0.96 8.8 1.0 3.0 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like SlyX PF04102.7 KFO97508.1 - 6.2 7.2 23.3 2 8.8 1.3 4.9 5 0 0 5 5 5 0 SlyX HR1 PF02185.11 KFO97508.1 - 8.8 6.1 24.2 1.3 8.8 2.3 4.1 3 1 1 4 4 4 0 Hr1 repeat IFP_35_N PF07334.8 KFO97508.1 - 9.3 6.2 8.6 7.8 6.5 0.4 2.8 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Filament PF00038.16 KFO97509.1 - 8e-117 390.1 22.7 9e-117 389.9 15.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFO97509.1 - 0.00051 17.9 5.7 0.00051 17.9 3.9 2.6 2 2 0 2 2 2 2 Myosin tail COG2 PF06148.6 KFO97509.1 - 0.036 13.9 5.9 0.044 13.6 0.2 3.3 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2773 PF10971.3 KFO97509.1 - 0.044 13.7 0.7 0.11 12.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) Transposase_22 PF02994.9 KFO97509.1 - 0.045 12.2 11.2 0.015 13.7 3.0 2.2 1 1 1 2 2 2 0 L1 transposable element DUF2551 PF10826.3 KFO97509.1 - 0.053 13.4 0.1 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) Baculo_PEP_C PF04513.7 KFO97509.1 - 0.074 12.8 11.3 0.75 9.6 0.3 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 KFO97509.1 - 0.11 11.8 9.8 0.066 12.5 1.2 2.9 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.6 KFO97509.1 - 0.17 11.7 10.3 1.7 8.6 0.1 4.4 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Sipho_Gp157 PF05565.6 KFO97509.1 - 0.21 11.1 8.2 1.1 8.8 0.5 2.6 2 1 0 2 2 2 0 Siphovirus Gp157 TPR_MLP1_2 PF07926.7 KFO97509.1 - 0.5 10.1 24.1 0.17 11.6 0.5 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 KFO97509.1 - 0.61 9.9 11.3 1.8 8.3 0.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ADIP PF11559.3 KFO97509.1 - 0.63 9.9 21.3 10 6.0 3.3 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KFO97509.1 - 0.79 8.8 5.8 2.6 7.1 1.2 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KFO97509.1 - 1 8.9 27.1 2 7.9 1.1 3.8 3 1 0 3 3 3 0 IncA protein Prefoldin PF02996.12 KFO97509.1 - 3.7 7.2 15.4 0.32 10.6 3.3 3.7 3 1 0 3 3 3 0 Prefoldin subunit FUSC PF04632.7 KFO97509.1 - 5.4 5.3 6.9 1.7 6.9 1.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Filament PF00038.16 KFO97510.1 - 7.2e-87 291.7 20.4 1.2e-86 291.0 14.1 1.3 1 1 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFO97510.1 - 9.3e-06 23.6 7.7 9.3e-06 23.6 5.4 2.1 2 0 0 2 2 2 1 Myosin tail TPR_MLP1_2 PF07926.7 KFO97510.1 - 0.00019 21.1 4.2 0.00019 21.1 2.9 4.3 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 KFO97510.1 - 0.027 13.9 19.0 0.36 10.3 0.3 4.5 2 1 2 4 4 4 0 Septum formation initiator DUF2312 PF10073.4 KFO97510.1 - 0.038 13.3 0.1 0.15 11.4 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF641 PF04859.7 KFO97510.1 - 0.41 10.3 9.4 0.76 9.5 0.4 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF45 PF01863.12 KFO97510.1 - 0.47 10.2 4.9 3.1 7.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF45 ERM PF00769.14 KFO97510.1 - 5.9 6.3 12.4 0.43 10.0 4.1 2.2 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Filament PF00038.16 KFO97511.1 - 2.2e-99 332.8 36.7 2.5e-99 332.7 25.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFO97511.1 - 9.4e-06 23.6 30.2 8.8e-05 20.4 6.9 2.1 2 0 0 2 2 2 2 Myosin tail Transposase_22 PF02994.9 KFO97511.1 - 0.00011 20.8 13.0 0.00011 20.8 9.0 2.3 1 1 0 2 2 2 1 L1 transposable element TPR_MLP1_2 PF07926.7 KFO97511.1 - 0.00083 19.1 4.0 0.00083 19.1 2.7 3.7 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFO97511.1 - 0.003 17.1 31.2 0.058 12.9 13.0 3.2 1 1 2 3 3 3 1 IncA protein ERM PF00769.14 KFO97511.1 - 0.19 11.2 27.2 0.56 9.6 4.2 2.6 2 2 0 2 2 2 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 KFO97511.1 - 0.24 11.2 30.2 0.44 10.3 1.0 3.6 2 1 0 3 3 3 0 Tropomyosin like DUF45 PF01863.12 KFO97511.1 - 0.64 9.7 7.3 1.1 8.9 0.1 2.7 2 1 2 4 4 4 0 Protein of unknown function DUF45 Kinetocho_Slk19 PF12709.2 KFO97511.1 - 2.2 8.3 24.8 2.8 8.0 0.1 5.2 3 2 2 5 5 5 0 Central kinetochore-associated Lzipper-MIP1 PF14389.1 KFO97511.1 - 2.5 8.2 24.8 0.28 11.3 3.4 4.5 2 2 3 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 Reo_sigmaC PF04582.7 KFO97511.1 - 2.7 7.1 12.1 0.84 8.7 2.0 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4140 PF13600.1 KFO97511.1 - 2.9 8.3 19.5 1.2 9.6 1.3 4.8 2 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF3114 PF11311.3 KFO97511.1 - 4.5 6.5 9.2 0.48 9.7 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3114) CENP-F_leu_zip PF10473.4 KFO97511.1 - 6.3 6.6 39.4 7.1 6.4 11.7 4.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.7 KFO97511.1 - 9.3 6.0 19.7 3.4 7.4 0.3 4.0 2 2 2 4 4 4 0 Plant protein of unknown function (DUF641) DUF883 PF05957.8 KFO97511.1 - 9.5 6.6 7.1 14 6.1 0.0 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Filament PF00038.16 KFO97512.1 - 3.9e-97 325.4 31.9 4.4e-97 325.3 22.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFO97512.1 - 7.2e-07 29.0 28.9 1.5e-06 27.9 0.2 3.3 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Transcrip_act PF04949.8 KFO97512.1 - 0.00097 18.8 4.8 0.46 10.1 0.2 2.7 1 1 2 3 3 3 2 Transcriptional activator WEMBL PF05701.6 KFO97512.1 - 0.0012 17.3 19.0 0.089 11.2 9.1 2.3 1 1 0 2 2 2 2 Weak chloroplast movement under blue light Laminin_II PF06009.7 KFO97512.1 - 0.0027 17.4 5.8 0.0027 17.4 4.0 3.0 2 1 1 3 3 3 1 Laminin Domain II AAA_13 PF13166.1 KFO97512.1 - 0.0079 14.7 18.2 0.37 9.1 12.4 2.2 1 1 0 1 1 1 1 AAA domain Tropomyosin_1 PF12718.2 KFO97512.1 - 0.011 15.6 27.1 0.011 15.5 8.4 3.6 2 2 1 3 3 3 0 Tropomyosin like Transposase_22 PF02994.9 KFO97512.1 - 0.012 14.1 20.7 0.028 12.9 9.9 2.7 1 1 2 3 3 3 0 L1 transposable element IncA PF04156.9 KFO97512.1 - 0.056 13.0 35.5 0.16 11.5 14.0 3.2 1 1 2 3 3 3 0 IncA protein HOOK PF05622.7 KFO97512.1 - 0.07 10.9 23.8 0.22 9.2 16.5 1.8 1 1 0 1 1 1 0 HOOK protein MADF_DNA_bdg PF10545.4 KFO97512.1 - 0.075 13.2 0.1 0.075 13.2 0.0 3.0 3 1 1 4 4 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Lectin_N PF03954.9 KFO97512.1 - 0.076 12.4 9.1 2.5 7.5 2.8 3.0 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF2312 PF10073.4 KFO97512.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.7 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Filo_VP35 PF02097.10 KFO97512.1 - 0.23 10.6 2.5 0.71 9.0 1.3 1.9 2 0 0 2 2 2 0 Filoviridae VP35 Phage_GP20 PF06810.6 KFO97512.1 - 0.32 10.4 16.9 0.024 14.0 3.8 2.9 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF720 PF05302.6 KFO97512.1 - 0.37 10.5 10.4 0.056 13.2 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF720) BLOC1_2 PF10046.4 KFO97512.1 - 0.42 10.7 20.3 0.14 12.2 4.9 4.2 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 KFO97512.1 - 0.44 10.4 0.0 0.44 10.4 0.0 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 KFO97512.1 - 0.58 10.0 34.4 3 7.6 0.3 4.4 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.1 KFO97512.1 - 0.7 9.8 27.2 0.15 12.0 10.5 3.8 4 0 0 4 4 3 0 FlxA-like protein DUF342 PF03961.8 KFO97512.1 - 1.8 6.8 22.4 2.3 6.5 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF342) ADIP PF11559.3 KFO97512.1 - 2 8.3 29.1 0.29 11.0 8.2 4.0 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KFO97512.1 - 2.3 8.6 15.0 7.5 7.0 1.3 4.4 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Kinetocho_Slk19 PF12709.2 KFO97512.1 - 2.9 8.0 25.7 0.26 11.4 2.7 4.8 5 0 0 5 5 5 0 Central kinetochore-associated Spc7 PF08317.6 KFO97512.1 - 3.1 6.3 25.4 0.056 12.0 8.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KFO97512.1 - 3.3 5.4 17.3 4.4 5.0 11.4 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Tho2 PF11262.3 KFO97512.1 - 3.3 6.6 12.2 0.18 10.7 3.5 2.2 2 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Fib_alpha PF08702.5 KFO97512.1 - 3.4 7.7 23.6 2.7 8.0 7.7 3.6 2 2 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF641 PF04859.7 KFO97512.1 - 4.5 7.0 13.8 19 5.0 1.0 3.8 2 2 2 4 4 4 0 Plant protein of unknown function (DUF641) PspA_IM30 PF04012.7 KFO97512.1 - 4.7 6.4 21.1 5.3 6.3 1.9 4.2 2 1 2 4 4 4 0 PspA/IM30 family DUF1664 PF07889.7 KFO97512.1 - 5.3 6.8 15.0 0.96 9.2 2.4 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 KFO97512.1 - 5.5 5.8 10.7 3.4 6.5 3.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) LOH1CR12 PF10158.4 KFO97512.1 - 7.9 6.2 13.5 19 5.0 2.2 4.1 1 1 4 5 5 5 0 Tumour suppressor protein Filament PF00038.16 KFO97513.1 - 1.2e-90 304.2 33.2 1.3e-90 304.0 23.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein Vps5 PF09325.5 KFO97513.1 - 0.00045 19.5 7.9 0.0075 15.5 0.8 2.5 1 1 1 2 2 2 2 Vps5 C terminal like Lectin_N PF03954.9 KFO97513.1 - 0.00046 19.5 7.0 0.28 10.6 0.6 3.3 1 1 2 3 3 3 2 Hepatic lectin, N-terminal domain Myosin_tail_1 PF01576.14 KFO97513.1 - 0.0015 16.3 4.5 0.0015 16.3 3.1 2.1 1 1 1 2 2 2 1 Myosin tail TPR_MLP1_2 PF07926.7 KFO97513.1 - 0.0028 17.4 25.9 0.0049 16.6 1.9 3.2 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein Transcrip_act PF04949.8 KFO97513.1 - 0.006 16.2 6.7 0.033 13.8 0.4 2.5 1 1 1 2 2 2 2 Transcriptional activator DUF4200 PF13863.1 KFO97513.1 - 0.0067 16.3 0.1 0.0067 16.3 0.0 4.0 4 1 1 5 5 4 2 Domain of unknown function (DUF4200) DUF720 PF05302.6 KFO97513.1 - 0.013 15.2 5.5 0.013 15.2 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF720) HXXSHH PF07586.6 KFO97513.1 - 0.036 12.9 0.2 0.036 12.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Hema_stalk PF08720.5 KFO97513.1 - 0.038 13.5 0.1 0.35 10.3 0.0 2.4 2 1 1 3 3 3 0 Influenza C hemagglutinin stalk ADIP PF11559.3 KFO97513.1 - 0.072 12.9 24.3 0.03 14.2 6.6 3.6 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 KFO97513.1 - 0.086 12.6 26.2 0.025 14.4 7.3 3.9 1 1 1 3 3 3 0 Tropomyosin like Orbi_VP5 PF00901.12 KFO97513.1 - 0.096 10.8 8.9 0.18 9.9 6.1 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Gp58 PF07902.6 KFO97513.1 - 0.16 10.1 4.3 0.19 9.8 3.0 1.2 1 0 0 1 1 1 0 gp58-like protein AAA_13 PF13166.1 KFO97513.1 - 0.28 9.5 17.7 0.24 9.8 11.0 1.8 1 1 0 1 1 1 0 AAA domain T2SM PF04612.7 KFO97513.1 - 0.61 9.8 8.7 5.7 6.7 0.0 2.7 3 0 0 3 3 2 0 Type II secretion system (T2SS), protein M CENP-F_leu_zip PF10473.4 KFO97513.1 - 0.64 9.8 34.8 0.091 12.6 3.7 4.2 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 KFO97513.1 - 1.3 8.8 14.7 0.17 11.6 4.9 2.7 1 1 3 4 4 4 0 Laminin Domain II Filo_VP35 PF02097.10 KFO97513.1 - 2 7.5 6.1 3.5 6.7 1.4 2.1 1 1 1 2 2 2 0 Filoviridae VP35 DUF2937 PF11157.3 KFO97513.1 - 2.9 7.1 9.1 0.5 9.6 1.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) DUF1664 PF07889.7 KFO97513.1 - 3.6 7.4 11.3 0.39 10.5 1.5 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.7 KFO97513.1 - 3.9 6.9 12.8 2.5 7.6 0.5 3.4 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Transposase_22 PF02994.9 KFO97513.1 - 4.1 5.7 18.3 0.21 10.0 8.0 1.9 1 1 0 2 2 2 0 L1 transposable element Kinetocho_Slk19 PF12709.2 KFO97513.1 - 5.3 7.1 21.7 2.1 8.4 1.7 5.1 3 2 1 5 5 5 0 Central kinetochore-associated FliD_C PF07195.7 KFO97513.1 - 6.6 5.9 11.9 0.27 10.5 2.6 2.4 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus VIT1 PF01988.14 KFO97513.1 - 7.5 5.9 6.3 8.3 5.8 3.0 2.1 1 1 1 2 2 2 0 VIT family Filament PF00038.16 KFO97514.1 - 1.4e-102 343.4 26.7 1.5e-102 343.2 18.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFO97514.1 - 3.3e-06 26.8 0.8 3.3e-06 26.8 0.6 3.5 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KFO97514.1 - 0.00032 20.5 32.4 0.0009 19.1 3.8 4.8 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.8 KFO97514.1 - 0.00082 19.0 7.4 0.00082 19.0 5.1 3.4 2 2 1 3 3 3 1 Nsp1-like C-terminal region Kinetocho_Slk19 PF12709.2 KFO97514.1 - 0.0013 18.7 14.2 0.077 13.0 0.5 4.4 4 1 1 5 5 5 2 Central kinetochore-associated DUF4200 PF13863.1 KFO97514.1 - 0.014 15.3 0.4 0.014 15.3 0.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 KFO97514.1 - 0.019 12.8 11.1 0.025 12.4 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 KFO97514.1 - 0.02 14.8 26.6 0.26 11.1 0.7 3.9 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 KFO97514.1 - 0.049 13.5 0.1 0.049 13.5 0.1 4.6 4 1 0 5 5 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KFO97514.1 - 0.059 13.1 15.5 0.27 11.0 1.8 3.5 3 1 1 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 KFO97514.1 - 0.078 12.7 21.8 2.9 7.6 1.5 5.0 4 1 1 5 5 4 0 Prefoldin subunit Myosin_tail_1 PF01576.14 KFO97514.1 - 0.12 10.0 24.8 0.16 9.6 7.1 2.7 2 1 0 2 2 2 0 Myosin tail BRE1 PF08647.6 KFO97514.1 - 0.16 11.9 11.2 0.36 10.8 1.4 3.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.2 KFO97514.1 - 0.21 11.4 23.2 0.59 9.9 7.1 3.4 3 1 0 3 3 3 0 Tropomyosin like MscS_porin PF12795.2 KFO97514.1 - 0.29 10.4 20.7 1.5 8.0 5.3 3.5 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain TBPIP PF07106.8 KFO97514.1 - 0.31 10.5 20.9 0.025 14.1 5.3 3.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IFT57 PF10498.4 KFO97514.1 - 0.38 9.4 19.1 0.77 8.4 6.5 2.9 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 DUF4140 PF13600.1 KFO97514.1 - 0.62 10.5 14.0 8 6.9 1.1 4.2 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.7 KFO97514.1 - 0.79 9.5 10.4 0.74 9.6 0.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.6 KFO97514.1 - 0.82 9.0 8.5 2.2 7.6 2.2 2.9 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 KFO97514.1 - 0.86 9.1 37.6 3.6 7.1 14.7 3.5 1 1 2 3 3 3 0 IncA protein HR1 PF02185.11 KFO97514.1 - 0.94 9.2 15.9 2.7 7.8 0.7 4.0 2 1 1 3 3 3 0 Hr1 repeat TMF_DNA_bd PF12329.3 KFO97514.1 - 1.2 9.0 16.4 11 5.9 0.0 4.5 4 1 1 5 5 4 0 TATA element modulatory factor 1 DNA binding Transposase_22 PF02994.9 KFO97514.1 - 3.4 6.0 20.2 0.31 9.4 7.2 2.4 2 1 0 2 2 2 0 L1 transposable element Spc7 PF08317.6 KFO97514.1 - 3.7 6.1 25.3 0.11 11.1 6.3 3.5 1 1 2 4 4 4 0 Spc7 kinetochore protein DUF745 PF05335.8 KFO97514.1 - 3.7 7.0 10.1 1.8 8.0 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.6 KFO97514.1 - 4.6 7.1 7.8 6.4 6.7 0.6 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 KFO97514.1 - 5 7.5 20.5 0.71 10.2 1.9 4.3 3 1 1 4 4 4 0 SlyX H-kinase_dim PF02895.9 KFO97514.1 - 9.7 6.6 7.6 23 5.4 0.2 3.1 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Filament PF00038.16 KFO97515.1 - 6.5e-105 351.0 26.3 7.3e-105 350.8 18.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFO97515.1 - 9.6e-06 25.3 24.6 1.1e-05 25.1 0.6 3.1 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KFO97515.1 - 0.0019 18.0 33.8 0.13 12.1 10.5 5.0 3 2 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kinetocho_Slk19 PF12709.2 KFO97515.1 - 0.017 15.1 16.8 1.1 9.3 1.1 4.5 4 1 1 5 5 5 0 Central kinetochore-associated DUF4200 PF13863.1 KFO97515.1 - 0.049 13.5 0.5 0.049 13.5 0.4 3.7 3 1 0 4 4 3 0 Domain of unknown function (DUF4200) DUF234 PF03008.9 KFO97515.1 - 0.052 13.6 1.2 0.15 12.2 0.9 1.7 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function Baculo_PEP_C PF04513.7 KFO97515.1 - 0.079 12.7 9.7 0.054 13.3 1.5 2.8 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MADF_DNA_bdg PF10545.4 KFO97515.1 - 0.13 12.4 4.4 0.53 10.5 0.1 3.4 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4140 PF13600.1 KFO97515.1 - 0.17 12.3 14.1 13 6.2 1.6 4.3 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 KFO97515.1 - 0.29 10.6 21.8 0.03 13.8 6.5 3.2 2 2 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KFO97515.1 - 0.29 10.6 36.9 0.13 11.8 13.8 3.6 1 1 2 3 3 3 0 IncA protein Prefoldin_2 PF01920.15 KFO97515.1 - 0.58 9.9 23.8 3.6 7.4 0.7 5.0 4 1 0 5 5 4 0 Prefoldin subunit FlaC_arch PF05377.6 KFO97515.1 - 0.68 9.8 13.7 0.8 9.6 0.0 4.7 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 KFO97515.1 - 0.93 9.6 16.6 0.52 10.4 2.1 4.3 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nsp1_C PF05064.8 KFO97515.1 - 1.1 8.8 19.2 0.2 11.2 7.1 3.3 2 2 1 3 3 3 0 Nsp1-like C-terminal region Tropomyosin_1 PF12718.2 KFO97515.1 - 1.2 8.9 23.1 4.5 7.1 0.0 3.4 3 0 0 3 3 3 0 Tropomyosin like HR1 PF02185.11 KFO97515.1 - 1.8 8.3 18.0 2.3 8.0 0.7 3.7 3 1 1 4 4 3 0 Hr1 repeat MscS_porin PF12795.2 KFO97515.1 - 1.9 7.7 19.1 4.8 6.4 3.3 3.6 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain FlxA PF14282.1 KFO97515.1 - 2.2 8.2 23.4 0.75 9.7 7.9 4.1 2 2 1 3 3 3 0 FlxA-like protein ADIP PF11559.3 KFO97515.1 - 2.4 8.0 27.1 0.47 10.3 1.2 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Cob_adeno_trans PF01923.13 KFO97515.1 - 2.5 7.8 8.3 0.62 9.8 1.4 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase TMF_DNA_bd PF12329.3 KFO97515.1 - 2.7 7.8 18.5 0.14 11.9 3.7 3.8 4 0 0 4 4 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KFO97515.1 - 3.4 7.2 21.3 4 6.9 0.2 5.0 5 0 0 5 5 5 0 Septum formation initiator NPV_P10 PF05531.7 KFO97515.1 - 4 7.7 10.9 10 6.4 0.7 3.8 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Transposase_22 PF02994.9 KFO97515.1 - 4.9 5.5 18.7 2.3 6.6 8.1 2.2 2 0 0 2 2 2 0 L1 transposable element Phage_GPO PF05929.6 KFO97515.1 - 5.5 6.1 8.5 3.8 6.6 2.0 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF342 PF03961.8 KFO97515.1 - 6.1 5.1 13.8 2.3 6.5 4.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF342) FliJ PF02050.11 KFO97515.1 - 8.1 6.5 19.0 1.2 9.2 7.2 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein COG2 PF06148.6 KFO97515.1 - 9.3 6.1 13.7 15 5.4 0.9 3.9 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.16 KFO97516.1 - 7e-97 324.6 23.8 7.9e-97 324.4 16.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 KFO97516.1 - 0.0042 16.9 29.6 0.2 11.4 7.4 4.2 3 1 1 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 KFO97516.1 - 0.01 15.3 11.8 0.01 15.3 8.2 3.2 2 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Dynein_heavy PF03028.10 KFO97516.1 - 0.011 13.8 4.0 0.018 13.1 2.7 1.3 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor MADF_DNA_bdg PF10545.4 KFO97516.1 - 0.022 14.9 0.2 0.022 14.9 0.2 3.4 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Kinetocho_Slk19 PF12709.2 KFO97516.1 - 0.023 14.7 17.9 0.69 10.0 2.3 4.4 3 1 0 4 4 4 0 Central kinetochore-associated SlyX PF04102.7 KFO97516.1 - 0.065 13.6 20.0 1.3 9.4 1.9 4.5 4 1 1 5 5 4 0 SlyX Spc7 PF08317.6 KFO97516.1 - 0.11 11.1 21.5 0.083 11.5 10.4 3.0 1 1 0 2 2 2 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 KFO97516.1 - 0.13 9.9 21.2 0.32 8.6 9.7 2.5 2 1 0 2 2 2 0 Myosin tail FlxA PF14282.1 KFO97516.1 - 0.32 10.9 18.5 0.18 11.7 7.7 3.6 4 0 0 4 4 4 0 FlxA-like protein Nsp1_C PF05064.8 KFO97516.1 - 0.57 9.8 14.7 0.11 12.1 6.2 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4140 PF13600.1 KFO97516.1 - 0.58 10.6 11.2 3.3 8.1 1.6 3.7 3 1 1 4 4 3 0 N-terminal domain of unknown function (DUF4140) Transposase_22 PF02994.9 KFO97516.1 - 0.7 8.3 17.8 0.048 12.1 8.8 1.5 2 0 0 2 2 2 0 L1 transposable element Spectrin PF00435.16 KFO97516.1 - 0.94 9.7 13.7 0.24 11.6 5.7 2.8 3 1 1 4 4 4 0 Spectrin repeat TPR_MLP1_2 PF07926.7 KFO97516.1 - 1.3 8.7 26.3 0.35 10.6 0.1 3.3 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFO97516.1 - 2 7.9 31.5 2.7 7.5 15.5 2.9 2 2 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 KFO97516.1 - 2.7 5.7 10.2 3.9 5.2 7.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 KFO97516.1 - 4.8 7.0 24.7 28 4.6 0.1 4.0 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.8 KFO97516.1 - 7.1 6.1 9.7 14 5.1 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Latarcin PF10279.4 KFO97516.1 - 7.4 6.8 7.7 4.3 7.6 0.3 3.3 3 1 0 3 3 3 0 Latarcin precursor Filament PF00038.16 KFO97517.1 - 3.7e-111 371.5 21.3 4.2e-111 371.3 14.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFO97517.1 - 0.001 16.9 5.0 0.001 16.9 3.5 2.7 2 2 0 2 2 2 1 Myosin tail DUF342 PF03961.8 KFO97517.1 - 0.11 10.9 11.0 0.25 9.7 0.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DUF2773 PF10971.3 KFO97517.1 - 0.13 12.2 1.9 0.63 10.0 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2773) SDH_beta PF03315.10 KFO97517.1 - 0.45 10.5 2.2 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Serine dehydratase beta chain Bacillus_HBL PF05791.6 KFO97517.1 - 0.63 9.3 7.6 0.44 9.8 0.9 2.4 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.5 KFO97517.1 - 0.71 9.9 9.1 6.4 6.8 0.2 3.8 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 KFO97517.1 - 1.9 8.8 15.6 23 5.4 0.0 5.1 4 1 1 5 5 5 0 SlyX Snapin_Pallidin PF14712.1 KFO97517.1 - 2.3 8.6 8.3 1.4 9.3 0.3 3.7 4 0 0 4 4 4 0 Snapin/Pallidin FlxA PF14282.1 KFO97517.1 - 2.8 7.9 10.9 8.8 6.3 0.0 3.6 3 1 1 4 4 4 0 FlxA-like protein COMP PF11598.3 KFO97517.1 - 3.4 7.8 9.6 4.7 7.3 0.4 3.8 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein ADIP PF11559.3 KFO97517.1 - 4.5 7.1 20.0 1.7 8.5 0.5 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KFO97517.1 - 6.5 6.3 21.1 0.57 9.7 0.5 4.6 6 0 0 6 6 6 0 Septum formation initiator Filament PF00038.16 KFO97518.1 - 3.1e-111 371.8 18.8 3.6e-111 371.6 13.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFO97518.1 - 0.0015 16.4 5.1 0.0015 16.4 3.5 2.9 2 2 0 2 2 2 1 Myosin tail DUF2773 PF10971.3 KFO97518.1 - 0.1 12.5 0.9 0.83 9.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) DivIC PF04977.10 KFO97518.1 - 0.57 9.7 18.7 0.74 9.3 0.5 4.4 5 0 0 5 5 5 0 Septum formation initiator DUF1664 PF07889.7 KFO97518.1 - 0.86 9.4 11.0 0.38 10.5 0.4 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 KFO97518.1 - 1.5 7.7 8.7 0.22 10.4 0.9 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) WXG100 PF06013.7 KFO97518.1 - 1.8 8.6 7.2 1.1 9.2 0.3 3.4 2 1 2 4 4 4 0 Proteins of 100 residues with WXG DUF4618 PF15397.1 KFO97518.1 - 1.8 7.8 13.9 0.042 13.1 3.4 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4618) DUF342 PF03961.8 KFO97518.1 - 2.5 6.4 8.7 5.1 5.4 2.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF342) ADIP PF11559.3 KFO97518.1 - 4.7 7.0 22.3 2.3 8.0 0.5 4.1 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 KFO97518.1 - 8.6 6.3 5.9 40 4.1 0.1 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Arm PF00514.18 KFO97519.1 - 1.3e-57 189.7 20.7 4.6e-10 38.9 0.0 11.9 12 0 0 12 12 12 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFO97519.1 - 8.2e-17 61.2 14.1 1.9e-06 28.0 0.7 5.9 4 2 2 6 6 6 6 HEAT repeats HEAT PF02985.17 KFO97519.1 - 4.5e-11 41.8 7.4 0.031 14.3 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.15 KFO97519.1 - 2.8e-07 29.2 8.5 7.3e-05 21.2 1.0 2.9 2 1 0 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 KFO97519.1 - 3.5e-07 29.6 1.0 0.048 12.7 0.1 3.7 1 1 1 3 3 3 3 V-ATPase subunit H Arm_2 PF04826.8 KFO97519.1 - 5.3e-05 22.4 3.8 0.34 9.9 0.1 5.2 4 2 2 6 6 6 1 Armadillo-like RIX1 PF08167.7 KFO97519.1 - 7.1e-05 22.5 3.6 0.22 11.2 0.1 3.0 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis RasGEF_N_2 PF14663.1 KFO97519.1 - 0.0025 17.7 7.0 12 5.9 0.0 5.6 5 1 3 8 8 8 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.1 KFO97519.1 - 0.0029 18.0 13.5 2 9.0 0.1 6.4 6 2 1 7 7 6 2 HEAT-like repeat Cnd1 PF12717.2 KFO97519.1 - 0.057 13.2 3.2 0.35 10.7 0.1 3.4 4 2 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.4 KFO97519.1 - 0.074 12.7 3.2 0.38 10.5 0.0 3.6 5 1 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain ATG16 PF08614.6 KFO97519.1 - 0.2 11.4 3.4 0.37 10.5 2.4 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FKBP_C PF00254.23 KFO97520.1 - 2.5e-100 328.7 0.0 4.1e-28 97.2 0.0 4.2 4 0 0 4 4 4 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.27 KFO97520.1 - 1.1e-07 30.5 0.4 0.00079 18.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KFO97520.1 - 2.2e-06 26.7 1.4 0.0025 17.1 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFO97520.1 - 1.5e-05 25.0 0.4 0.0001 22.3 0.3 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFO97520.1 - 8.4e-05 22.1 0.0 0.25 11.3 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFO97520.1 - 0.00061 19.3 0.1 0.0012 18.4 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair UMPH-1 PF05822.7 KFO97521.1 - 7.8e-119 395.4 0.3 9.1e-119 395.2 0.2 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 KFO97521.1 - 0.00011 22.4 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFO97521.1 - 0.022 14.9 0.0 0.055 13.6 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase BACK PF07707.10 KFO97522.1 - 8.8e-29 99.3 3.0 7e-28 96.4 1.1 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFO97522.1 - 1.9e-21 75.3 2.8 2.2e-06 27.0 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 KFO97522.1 - 2e-21 75.2 1.3 9e-05 22.4 0.0 5.0 3 1 2 5 5 5 4 Kelch motif Kelch_3 PF13415.1 KFO97522.1 - 1.2e-11 44.4 0.1 0.014 15.5 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFO97522.1 - 1.1e-09 37.8 0.0 2.6 7.8 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.26 KFO97522.1 - 6.2e-07 29.3 0.1 2.2e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KFO97522.1 - 1.1e-06 28.1 2.2 0.91 9.3 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 KFO97522.1 - 0.039 13.9 4.5 3.7 7.5 0.0 3.8 4 0 0 4 4 4 0 Kelch motif LVIVD PF08309.6 KFO97522.1 - 0.079 11.9 0.3 8.6 5.4 0.1 2.5 2 0 0 2 2 2 0 LVIVD repeat Citrate_synt PF00285.16 KFO97523.1 - 2.2e-22 79.3 0.0 3.8e-20 71.9 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 KFO97523.1 - 2.1e-13 50.1 0.0 4.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KFO97523.1 - 5.8e-10 39.5 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 KFO97523.1 - 4.3e-08 32.7 0.0 8.9e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 KFO97523.1 - 0.00034 20.2 0.0 0.0031 17.1 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 KFO97523.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain TPR_11 PF13414.1 KFO97524.1 - 1.3e-24 85.5 15.2 6.2e-14 51.4 1.2 5.3 5 0 0 5 5 5 4 TPR repeat TPR_2 PF07719.12 KFO97524.1 - 6.5e-23 78.7 17.2 0.0016 18.2 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFO97524.1 - 1.5e-22 78.1 14.4 0.001 18.5 0.1 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFO97524.1 - 4.2e-21 74.6 13.9 2.7e-06 27.2 0.5 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFO97524.1 - 1.8e-13 49.1 10.7 0.052 13.3 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFO97524.1 - 2.3e-10 39.4 10.3 0.0057 16.3 0.0 7.3 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97524.1 - 1.7e-09 38.1 7.0 0.00067 20.2 0.0 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO97524.1 - 9.2e-06 25.7 13.0 0.019 15.0 0.0 4.0 3 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFO97524.1 - 1.7e-05 25.0 7.2 8 7.4 0.0 6.7 4 2 4 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFO97524.1 - 4.5e-05 23.2 5.1 0.047 13.5 0.2 4.6 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO97524.1 - 0.0019 18.5 7.1 19 5.9 0.0 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFO97524.1 - 0.0022 17.8 7.4 0.79 9.7 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97524.1 - 0.016 15.5 12.9 0.13 12.6 0.6 5.1 3 3 2 5 5 5 0 Tetratricopeptide repeat Apc5 PF12862.2 KFO97524.1 - 0.017 14.9 0.5 1.5 8.6 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.1 KFO97524.1 - 0.024 14.8 11.1 21 5.6 0.4 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.15 KFO97524.1 - 0.045 13.7 0.2 74 3.6 0.0 4.3 4 0 0 4 4 4 0 PPR repeat DUF2225 PF09986.4 KFO97524.1 - 0.25 10.7 5.4 0.18 11.2 1.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 KFO97524.1 - 0.59 9.4 10.1 0.59 9.4 0.1 3.8 3 2 1 4 4 3 0 26S proteasome subunit RPN7 MIT PF04212.13 KFO97524.1 - 2.9 7.8 0.0 2.9 7.8 0.0 4.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain CNPase PF05881.7 KFO97525.1 - 1.7e-117 390.8 0.1 2.3e-117 390.4 0.0 1.2 1 0 0 1 1 1 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) AAA_17 PF13207.1 KFO97525.1 - 1.3e-07 32.4 0.2 3e-07 31.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFO97525.1 - 3.8e-07 30.0 0.0 6.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFO97525.1 - 5.9e-07 28.7 0.1 9.1e-06 24.9 0.0 2.5 1 1 1 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KFO97525.1 - 3.6e-06 27.1 1.1 0.00011 22.4 0.2 3.2 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KFO97525.1 - 6.6e-06 26.0 0.4 0.00069 19.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain 6PF2K PF01591.13 KFO97525.1 - 0.00014 20.9 0.1 0.14 11.2 0.0 2.2 1 1 1 2 2 2 2 6-phosphofructo-2-kinase ABC_tran PF00005.22 KFO97525.1 - 0.00023 21.4 0.0 0.00056 20.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 KFO97525.1 - 0.00068 19.6 0.2 0.0031 17.5 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFO97525.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFO97525.1 - 0.0011 17.9 0.6 0.055 12.3 0.4 2.3 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.24 KFO97525.1 - 0.0023 18.1 0.0 0.0064 16.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFO97525.1 - 0.0028 17.3 0.0 0.0082 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFO97525.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain tRNA_lig_kinase PF08303.6 KFO97525.1 - 0.0058 16.5 0.1 0.0099 15.7 0.1 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_30 PF13604.1 KFO97525.1 - 0.012 15.2 0.0 0.049 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFO97525.1 - 0.018 14.5 0.0 0.089 12.2 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain CPT PF07931.7 KFO97525.1 - 0.021 14.4 0.0 0.056 13.0 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 KFO97525.1 - 0.028 14.7 1.5 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFO97525.1 - 0.035 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 KFO97525.1 - 0.048 12.5 0.0 0.33 9.7 0.0 2.0 1 1 1 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 KFO97525.1 - 0.058 12.9 0.8 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.5 KFO97525.1 - 0.059 12.5 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 KFO97525.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 KFO97525.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KFO97525.1 - 0.11 12.1 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 KFO97525.1 - 0.14 11.7 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TPR_11 PF13414.1 KFO97526.1 - 8.8e-27 92.5 7.7 2.5e-19 68.6 2.6 3.0 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 KFO97526.1 - 5.8e-21 72.6 6.7 1.2e-06 27.9 1.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFO97526.1 - 1.6e-20 71.7 8.3 6.8e-07 28.6 2.6 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97526.1 - 3.4e-13 49.8 2.6 1.4e-06 28.7 0.3 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFO97526.1 - 2.3e-11 42.6 4.0 0.00016 21.2 1.6 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97526.1 - 4.3e-10 39.7 1.5 0.00098 19.4 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFO97526.1 - 4.8e-10 39.2 6.8 0.00085 19.2 0.1 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFO97526.1 - 6.9e-09 35.2 7.7 1.6e-05 24.7 0.1 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFO97526.1 - 2.1e-08 34.0 0.3 0.011 16.3 0.0 4.2 2 2 2 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KFO97526.1 - 5.6e-08 32.8 6.8 0.00024 21.1 0.7 3.0 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFO97526.1 - 7.2e-08 32.1 2.6 0.075 12.8 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFO97526.1 - 1e-05 25.6 3.5 0.16 12.4 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFO97526.1 - 0.00069 19.8 1.7 0.49 10.9 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFO97526.1 - 0.0039 16.8 2.2 3.9 7.5 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFO97526.1 - 0.009 15.7 3.6 0.05 13.4 2.6 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFO97526.1 - 0.01 15.7 3.7 7 6.7 0.3 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFO97526.1 - 0.021 15.0 1.3 12 6.1 0.0 2.9 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation MIT PF04212.13 KFO97526.1 - 0.056 13.3 0.8 0.056 13.3 0.6 2.1 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 KFO97526.1 - 0.074 12.0 1.6 5.3 6.0 0.0 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 KFO97526.1 - 0.095 11.4 2.3 2.4 6.7 0.2 2.5 1 1 1 3 3 3 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 KFO97526.1 - 0.11 12.4 4.5 4.1 7.3 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF4398 PF14346.1 KFO97526.1 - 6.5 6.8 6.3 16 5.6 0.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4398) Ras PF00071.17 KFO97527.1 - 9.9e-19 67.2 0.1 1.1e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97527.1 - 1.6e-09 38.2 0.0 2.8e-09 37.5 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFO97527.1 - 0.0002 20.6 0.1 0.00022 20.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2121 PF09894.4 KFO97527.1 - 0.0091 15.3 0.1 0.042 13.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2121) GTP_EFTU PF00009.22 KFO97527.1 - 0.023 14.1 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SpoIIP PF07454.6 KFO97527.1 - 0.05 12.7 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) zf-met PF12874.2 KFO97528.1 - 8.8e-30 101.9 27.9 7.5e-08 32.3 0.3 5.0 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO97528.1 - 1.5e-24 85.4 26.5 6.2e-08 32.5 1.7 5.1 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFO97528.1 - 2.1e-08 34.1 21.1 0.003 17.6 0.2 4.3 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 KFO97528.1 - 1.7e-07 31.1 6.1 0.036 13.8 0.1 4.2 4 0 0 4 4 4 3 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.7 KFO97528.1 - 7.9e-06 25.3 14.6 0.09 12.3 0.0 4.3 4 0 0 4 4 4 3 U1 zinc finger ZF-HD_dimer PF04770.7 KFO97528.1 - 0.0037 17.2 0.1 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 ZF-HD protein dimerisation region zf-DHHC PF01529.15 KFO97528.1 - 0.042 13.2 0.4 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase Cys_rich_CPCC PF14206.1 KFO97528.1 - 0.12 11.9 1.9 19 4.9 0.0 3.3 4 0 0 4 4 4 0 Cysteine-rich CPCC zf-C2H2_4 PF13894.1 KFO97528.1 - 0.34 11.3 19.5 1.3 9.5 1.1 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO97528.1 - 0.7 10.3 22.2 4.2 7.9 1.0 4.8 5 1 1 6 6 5 0 Zinc finger, C2H2 type zf-BED PF02892.10 KFO97528.1 - 1.1 9.0 8.3 2.2 8.0 0.1 3.7 3 0 0 3 3 3 0 BED zinc finger Cas_CXXC_CXXC PF09706.5 KFO97528.1 - 5.1 7.3 6.7 20 5.4 0.1 4.0 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) TFIIA PF03153.8 KFO97528.1 - 5.8 6.6 8.2 12 5.7 5.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIG-I_C-RD PF11648.3 KFO97529.1 - 3.1e-40 136.8 3.0 6.4e-40 135.8 2.1 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I Helicase_C PF00271.26 KFO97529.1 - 1.2e-18 66.6 0.1 5.8e-18 64.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFO97529.1 - 1.2e-08 35.0 0.3 3.1e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFO97529.1 - 3.2e-07 29.9 0.5 1.1e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KFO97529.1 - 5.6e-05 22.0 0.1 5.6e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain CHAD PF05235.9 KFO97529.1 - 0.0042 16.7 0.6 0.2 11.2 0.1 2.5 2 0 0 2 2 2 1 CHAD domain DUF3666 PF12408.3 KFO97529.1 - 0.018 14.1 0.4 0.044 12.8 0.3 1.6 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase PSD4 PF07631.6 KFO97529.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) AAA_11 PF13086.1 KFO97529.1 - 1.1 8.7 6.4 0.19 11.2 0.5 2.4 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KFO97529.1 - 1.6 8.9 6.0 0.27 11.4 0.2 2.7 4 0 0 4 4 4 0 AAA domain PCAF_N PF06466.6 KFO97530.1 - 1.9e-133 443.4 1.1 2.7e-133 442.9 0.7 1.2 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.20 KFO97530.1 - 4.6e-25 87.3 0.4 1.1e-24 86.0 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KFO97530.1 - 1.4e-11 44.3 0.6 4e-11 42.9 0.4 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFO97530.1 - 1.3e-09 37.9 0.1 2.6e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ras PF00071.17 KFO97531.1 - 1.1e-52 177.7 0.3 1.4e-52 177.3 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97531.1 - 5.1e-12 46.3 0.1 1.9e-11 44.4 0.0 1.9 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFO97531.1 - 2.8e-07 29.9 0.0 4.2e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFO97531.1 - 0.00083 19.3 0.0 0.0011 18.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFO97531.1 - 0.0034 16.5 0.0 0.0066 15.6 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KFO97531.1 - 0.069 12.3 0.1 0.15 11.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFO97531.1 - 0.072 12.5 0.2 0.23 10.8 0.1 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFO97531.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain PAS_9 PF13426.1 KFO97532.1 - 6.8e-20 71.3 0.0 1.8e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 PAS domain Ion_trans PF00520.26 KFO97532.1 - 5.1e-17 61.7 8.5 1e-16 60.7 5.9 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFO97532.1 - 3e-10 39.6 1.0 3e-10 39.6 0.7 2.9 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.24 KFO97532.1 - 2.1e-09 37.0 0.0 4.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS_4 PF08448.5 KFO97532.1 - 5.2e-07 29.6 0.0 9.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KFO97532.1 - 4.5e-06 26.4 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 KFO97532.1 - 4.6e-06 26.6 0.0 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold Ion_trans_N PF08412.5 KFO97532.1 - 0.019 14.2 1.0 0.041 13.1 0.1 2.0 2 0 0 2 2 2 0 Ion transport protein N-terminal Orexin PF02072.10 KFO97533.1 - 8.7e-48 161.3 4.7 9.4e-48 161.2 3.3 1.0 1 0 0 1 1 1 1 Prepro-orexin DUF350 PF03994.9 KFO97533.1 - 0.096 12.4 2.0 6.8 6.5 0.0 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF350) PI-PLC-Y PF00387.14 KFO97534.1 - 1.2e-41 141.3 0.1 2.4e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.14 KFO97534.1 - 2.1e-40 137.4 0.0 3.7e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.6 KFO97534.1 - 1.8e-25 88.7 0.0 3.5e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFO97534.1 - 2.6e-14 52.8 0.0 7.1e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH PF00169.24 KFO97534.1 - 3.7e-05 23.8 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 KFO97534.1 - 0.0035 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology STAT_bind PF02864.10 KFO97535.1 - 4.6e-99 331.1 3.8 5.7e-99 330.8 2.6 1.1 1 0 0 1 1 1 1 STAT protein, DNA binding domain SH2 PF00017.19 KFO97535.1 - 1e-11 44.4 0.0 5.9e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 SH2 domain STAT_bind PF02864.10 KFO97536.1 - 3.6e-128 426.5 0.4 2.9e-127 423.5 0.2 2.2 2 0 0 2 2 2 1 STAT protein, DNA binding domain STAT_alpha PF01017.15 KFO97536.1 - 1.6e-58 197.4 18.1 3e-58 196.5 12.5 1.5 1 0 0 1 1 1 1 STAT protein, all-alpha domain STAT_int PF02865.12 KFO97536.1 - 8.1e-42 142.1 8.1 8.1e-42 142.1 5.6 2.8 2 1 2 4 4 4 1 STAT protein, protein interaction domain SH2 PF00017.19 KFO97536.1 - 8.9e-14 51.0 0.0 2.4e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Syntaxin-6_N PF09177.6 KFO97536.1 - 0.0037 17.6 0.9 0.0037 17.6 0.6 2.9 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 KFO97536.1 - 0.54 10.0 9.9 0.24 11.2 4.0 2.1 2 0 0 2 2 2 0 Tropomyosin like Fib_alpha PF08702.5 KFO97536.1 - 0.62 10.1 13.6 0.24 11.5 6.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family eIF3_N PF09440.5 KFO97536.1 - 0.75 9.9 11.0 4.9 7.3 1.3 3.2 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain MerR-DNA-bind PF09278.6 KFO97536.1 - 1.4 9.3 14.0 1.6 9.1 0.3 4.0 4 0 0 4 4 4 0 MerR, DNA binding DUF342 PF03961.8 KFO97536.1 - 4.5 5.5 8.0 0.41 9.0 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KFO97537.1 - 0 1033.2 0.0 0 1033.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family NAGLU PF05089.7 KFO97538.1 - 1.2e-115 385.8 0.0 1.5e-115 385.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 KFO97538.1 - 4.2e-87 291.9 0.1 5.5e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain adh_short PF00106.20 KFO97539.1 - 2.1e-27 96.0 0.1 2.6e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFO97539.1 - 1.6e-10 41.1 0.0 1.8e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFO97539.1 - 9.8e-10 38.3 0.0 1.2e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFO97539.1 - 0.00015 21.0 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KFO97539.1 - 0.0031 17.2 0.1 0.0056 16.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KFO97539.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding HLH PF00010.21 KFO97540.1 - 2.8e-16 58.9 0.1 9.4e-16 57.2 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FAM91_C PF14648.1 KFO97540.1 - 0.065 12.0 0.6 0.071 11.9 0.4 1.2 1 0 0 1 1 1 0 FAM91 C-terminus RNA_pol_Rpb4 PF03874.11 KFO97540.1 - 0.085 12.8 3.3 0.3 11.1 1.9 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb4 GIDA PF01134.17 KFO97540.1 - 0.093 11.5 0.6 0.1 11.4 0.4 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A TBPIP PF07106.8 KFO97541.1 - 1.1e-15 57.6 1.1 2.1e-15 56.6 0.3 1.7 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 KFO97541.1 - 0.00013 20.5 0.3 0.00015 20.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Scaffolding_pro PF11418.3 KFO97541.1 - 0.12 12.6 0.7 0.18 12.1 0.5 1.3 1 0 0 1 1 1 0 Phi29 scaffolding protein Reticulon PF02453.12 KFO97542.1 - 0.015 14.9 0.1 0.015 14.9 0.1 1.6 2 0 0 2 2 2 0 Reticulon Tubulin PF00091.20 KFO97543.1 - 2.6e-54 184.3 0.0 4.8e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFO97543.1 - 4.8e-48 162.3 0.1 8.9e-48 161.4 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain MyTH4 PF00784.12 KFO97545.1 - 5.4e-21 74.6 0.0 9.5e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 MyTH4 domain RA PF00788.18 KFO97545.1 - 1.1e-06 29.0 0.0 2.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFO97545.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 PH domain F5_F8_type_C PF00754.20 KFO97546.1 - 4.7e-10 39.3 0.5 5.4e-10 39.2 0.4 1.0 1 0 0 1 1 1 1 F5/8 type C domain Laminin_G_2 PF02210.19 KFO97547.1 - 1.3e-18 67.2 1.5 5e-16 58.9 0.2 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFO97547.1 - 6.9e-14 51.9 0.0 7.6e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.19 KFO97548.1 - 3.8e-56 188.6 0.0 2.2e-20 72.9 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 KFO97548.1 - 5.2e-35 120.3 0.0 7.2e-11 42.2 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain Fibrinogen_C PF00147.13 KFO97548.1 - 4.2e-05 23.2 0.0 7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Laminin_G_3 PF13385.1 KFO97548.1 - 5.4e-05 23.4 0.0 0.0048 17.1 0.0 3.0 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 KFO97548.1 - 0.00015 21.6 3.5 0.00015 21.6 2.4 3.5 3 0 0 3 3 3 2 EGF-like domain SET PF00856.23 KFO97549.1 - 5.8e-23 81.9 0.3 3.4e-22 79.4 0.2 2.4 1 1 0 1 1 1 1 SET domain EZH2_WD-Binding PF11616.3 KFO97549.1 - 5.3e-16 58.1 0.1 1.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 WD repeat binding protein EZH2 ESCRT-II PF05871.7 KFO97550.1 - 5e-30 104.2 0.4 7.2e-30 103.7 0.1 1.3 2 0 0 2 2 2 1 ESCRT-II complex subunit Cyclin_N PF00134.18 KFO97551.1 - 1e-08 34.8 0.7 0.00015 21.2 0.1 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain DEP PF00610.16 KFO97551.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APG6 PF04111.7 KFO97552.1 - 1.7e-128 428.1 12.6 1.9e-128 427.9 8.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 BH3 PF15285.1 KFO97552.1 - 1.5e-17 62.6 0.2 2.4e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting DUF972 PF06156.8 KFO97552.1 - 0.023 15.0 6.8 0.023 15.0 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF342 PF03961.8 KFO97552.1 - 0.041 12.3 13.7 0.053 11.9 9.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) MT PF12777.2 KFO97552.1 - 0.64 8.7 8.9 1.1 7.8 6.2 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor ALMT PF11744.3 KFO97552.1 - 1.2 7.6 4.0 1.8 7.1 2.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.14 KFO97552.1 - 1.7 6.3 9.0 2.2 5.9 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Transposase_22 PF02994.9 KFO97552.1 - 2 6.8 14.1 3.1 6.1 9.8 1.3 1 0 0 1 1 1 0 L1 transposable element DUF740 PF05340.7 KFO97552.1 - 2 6.6 7.2 3.2 6.0 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF3450 PF11932.3 KFO97552.1 - 4 6.6 16.1 0.7 9.1 4.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.1 KFO97552.1 - 4.3 6.4 26.1 0.28 10.3 7.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PA28_beta PF02252.13 KFO97553.1 - 4.1e-69 230.8 2.6 5.3e-69 230.4 1.8 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 KFO97553.1 - 5.6e-28 96.9 1.3 1.1e-27 95.9 0.9 1.5 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit DUF4420 PF14390.1 KFO97553.1 - 0.057 12.2 0.1 0.1 11.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4420) GnsAB PF08178.6 KFO97553.1 - 0.13 11.8 0.8 0.48 10.1 0.0 2.3 3 0 0 3 3 3 0 GnsA/GnsB family Cu_amine_oxid PF01179.15 KFO97554.1 - 1.3e-124 416.0 0.1 1.7e-124 415.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFO97554.1 - 4.8e-14 52.2 0.0 9.3e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFO97554.1 - 3.4e-10 39.8 0.0 7.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.5 KFO97554.1 - 0.00062 19.6 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.15 KFO97555.1 - 3.1e-124 414.8 0.0 3.7e-124 414.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFO97555.1 - 2e-14 53.4 0.0 3.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFO97555.1 - 7.3e-11 41.9 0.0 1.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.5 KFO97555.1 - 0.0084 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) PAP2 PF01569.16 KFO97556.1 - 6.6e-15 54.9 7.5 6.6e-15 54.9 5.2 2.1 1 1 1 2 2 2 1 PAP2 superfamily tRNA_SAD PF07973.9 KFO97557.1 - 1.8e-10 40.4 0.2 4.2e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CS PF04969.11 KFO97557.1 - 9.4e-06 26.0 0.2 1.9e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 CS domain DUF4378 PF14309.1 KFO97557.1 - 0.015 15.3 0.6 0.039 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) Nod_GRP PF07806.6 KFO97557.1 - 0.1 12.2 2.3 0.23 11.1 1.6 1.5 1 0 0 1 1 1 0 Nodule-specific GRP repeat RUN PF02759.14 KFO97558.1 - 1.8e-31 108.6 0.0 3.2e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 RUN domain Ribosomal_L27e PF01777.13 KFO97560.1 - 8.1e-39 131.6 7.7 9.4e-39 131.4 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family NID PF07292.8 KFO97561.1 - 5.3e-36 122.5 0.0 9.5e-21 73.6 0.1 2.5 2 1 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_6 PF14259.1 KFO97561.1 - 0.14 12.1 0.0 0.62 10.0 0.0 2.1 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 KFO97562.1 - 4.2e-19 68.5 0.0 7e-19 67.7 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFO97562.1 - 0.00015 22.2 0.0 0.00081 19.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein OB_NTP_bind PF07717.11 KFO97563.1 - 2e-30 104.9 0.0 3.5e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFO97563.1 - 1.8e-29 101.7 0.2 3.5e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFO97563.1 - 3.2e-12 46.1 0.0 6.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFO97563.1 - 4e-06 26.4 0.2 3.6e-05 23.3 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFO97563.1 - 0.0027 17.8 0.9 0.0088 16.1 0.3 2.1 2 1 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 KFO97563.1 - 0.023 14.4 0.1 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 KFO97563.1 - 0.076 12.6 0.1 1.4 8.5 0.0 2.7 2 1 1 3 3 3 0 Helicase AAA_19 PF13245.1 KFO97563.1 - 0.11 12.2 0.3 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain ETS_PEA3_N PF04621.8 KFO97564.1 - 2.2e-95 319.7 25.9 4.4e-94 315.5 18.0 2.1 1 1 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.17 KFO97564.1 - 6.5e-38 128.7 0.2 1e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 Ets-domain Homeobox PF00046.24 KFO97565.1 - 5.3e-24 83.5 7.7 6.6e-24 83.2 5.4 1.1 1 0 0 1 1 1 1 Homeobox domain DUF2316 PF10078.4 KFO97565.1 - 0.044 13.7 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Terminase_5 PF06056.7 KFO97565.1 - 0.062 12.8 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Sclerostin PF05463.6 KFO97566.1 - 1.7e-72 243.1 6.9 1.9e-72 242.9 4.8 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) DAN PF03045.10 KFO97566.1 - 3.7e-09 36.0 1.9 5.1e-09 35.5 1.3 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 KFO97566.1 - 1e-05 25.5 2.1 1.7e-05 24.8 1.5 1.3 1 0 0 1 1 1 1 Cystine-knot domain DSPc PF00782.15 KFO97567.1 - 7.4e-34 116.1 0.1 8.8e-34 115.9 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO97567.1 - 2.5e-05 23.7 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KFO97567.1 - 0.00021 20.2 0.0 0.00022 20.2 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 KFO97567.1 - 0.00035 20.6 0.0 0.00048 20.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF442 PF04273.8 KFO97567.1 - 0.02 14.7 0.0 0.066 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative phosphatase (DUF442) APG12 PF04110.8 KFO97567.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Ras PF00071.17 KFO97568.1 - 5.4e-56 188.4 0.1 9.5e-56 187.6 0.0 1.4 2 0 0 2 2 2 1 Ras family Arf PF00025.16 KFO97568.1 - 3.9e-17 62.0 0.1 4.8e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFO97568.1 - 8.5e-17 61.7 0.0 1.2e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFO97568.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFO97568.1 - 3.7e-05 23.6 0.0 0.00069 19.5 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFO97568.1 - 0.00072 19.0 0.0 0.0014 18.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFO97568.1 - 0.039 13.1 0.0 0.071 12.3 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KFO97568.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Guanylate_kin PF00625.16 KFO97569.1 - 6e-41 139.9 1.2 1e-40 139.1 0.8 1.4 1 0 0 1 1 1 1 Guanylate kinase L27 PF02828.11 KFO97569.1 - 8.5e-25 86.2 3.3 4.8e-13 48.5 0.2 2.8 2 0 0 2 2 2 2 L27 domain PDZ PF00595.19 KFO97569.1 - 3.5e-12 46.3 0.9 8e-12 45.1 0.7 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO97569.1 - 7.4e-06 25.7 0.1 2.3e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 PDZ domain SH3_1 PF00018.23 KFO97569.1 - 0.0024 17.2 0.0 0.0052 16.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF4186 PF13811.1 KFO97569.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) NPBW PF15180.1 KFO97569.1 - 0.058 13.0 0.3 12 5.5 0.0 2.7 3 0 0 3 3 3 0 Neuropeptides B and W Cytochrom_B561 PF03188.11 KFO97570.1 - 1.6e-42 144.5 9.8 1.6e-42 144.5 6.8 1.8 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF4525 PF15027.1 KFO97570.1 - 0.15 11.5 0.2 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Ank_2 PF12796.2 KFO97571.1 - 2.8e-79 261.5 13.7 4.8e-22 78.0 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFO97571.1 - 6.8e-62 202.3 11.1 1.6e-07 30.7 0.0 11.5 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.1 KFO97571.1 - 7.5e-55 182.3 3.2 7.2e-10 39.1 0.0 7.6 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO97571.1 - 1.5e-41 139.4 8.4 2.8e-10 40.1 0.1 8.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO97571.1 - 2e-41 135.8 1.5 0.00076 19.4 0.0 11.0 10 0 0 10 10 10 7 Ankyrin repeat TPR_11 PF13414.1 KFO97571.1 - 4.3e-14 51.9 7.2 3.8e-09 36.0 1.4 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFO97571.1 - 3.7e-11 42.0 6.7 0.00081 19.1 0.9 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFO97571.1 - 1e-07 31.2 8.2 0.00047 19.6 0.8 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFO97571.1 - 1.2e-06 27.8 0.9 0.019 14.7 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO97571.1 - 1.2e-06 28.5 1.4 0.00012 22.3 0.4 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFO97571.1 - 6e-06 26.0 0.3 0.00012 21.8 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97571.1 - 1.9e-05 25.1 4.8 0.015 15.9 0.6 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97571.1 - 3.2e-05 24.1 1.5 0.00033 20.9 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFO97571.1 - 4e-05 23.4 1.7 0.0038 17.1 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.1 KFO97571.1 - 0.0033 17.4 0.1 0.0033 17.4 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain Miro PF08477.8 KFO97571.1 - 0.034 14.6 0.0 0.088 13.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TPR_17 PF13431.1 KFO97571.1 - 0.036 14.2 1.8 0.18 12.1 0.3 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFO97571.1 - 0.084 12.7 0.5 2.7 7.9 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFO97571.1 - 0.65 10.5 5.9 10 6.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 KFO97573.1 - 4.2e-15 55.8 0.0 7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO97573.1 - 1.2e-13 51.3 0.0 2.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO97573.1 - 6.2e-11 42.1 0.0 1.7e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO97573.1 - 1.2e-10 41.7 0.0 2.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO97573.1 - 1.3e-08 35.0 0.0 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO97573.1 - 7.8e-08 32.8 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFO97573.1 - 0.00066 19.6 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFO97573.1 - 0.0022 17.4 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 KFO97573.1 - 0.033 13.4 0.0 0.94 8.7 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain TPMT PF05724.6 KFO97573.1 - 0.039 13.4 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FmrO PF07091.6 KFO97573.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Integrin_beta PF00362.13 KFO97574.1 - 6.2e-180 598.6 0.0 6.2e-180 598.6 0.0 1.6 2 0 0 2 2 2 1 Integrin, beta chain Integrin_B_tail PF07965.7 KFO97574.1 - 4.8e-21 74.9 9.1 4.8e-21 74.9 6.3 4.3 3 1 1 4 4 4 1 Integrin beta tail domain Integrin_b_cyt PF08725.6 KFO97574.1 - 1.8e-09 36.8 1.3 1.8e-09 36.8 0.9 2.2 2 0 0 2 2 2 1 Integrin beta cytoplasmic domain EGF_2 PF07974.8 KFO97574.1 - 1.8e-09 37.5 100.0 7.2e-05 22.8 11.0 6.7 5 1 1 6 6 6 3 EGF-like domain HemY_N PF07219.8 KFO97575.1 - 0.029 13.9 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 HemY protein N-terminus Tmemb_9 PF05434.6 KFO97575.1 - 0.038 13.7 0.1 0.045 13.5 0.1 1.1 1 0 0 1 1 1 0 TMEM9 DUF1072 PF06380.6 KFO97575.1 - 0.12 12.0 7.5 0.27 10.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) 7tm_2 PF00002.19 KFO97576.1 - 7.6e-78 260.9 21.8 9.3e-78 260.6 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFO97576.1 - 5.7e-18 64.6 2.7 5.7e-18 64.6 1.1 1.7 2 0 0 2 2 2 1 Hormone receptor domain DUF2976 PF11190.3 KFO97576.1 - 0.31 10.5 4.4 4.2 6.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) zf-H2C2_2 PF13465.1 KFO97577.1 - 1.2e-61 202.1 64.0 3.3e-10 39.7 0.4 8.4 9 0 0 9 9 8 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFO97577.1 - 7e-38 126.7 65.2 1.7e-05 24.8 0.6 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFO97577.1 - 9.5e-26 89.2 24.7 0.00014 21.9 0.0 8.1 7 1 1 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFO97577.1 - 9.3e-21 72.5 54.1 0.002 18.3 0.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO97577.1 - 5.9e-19 67.2 46.4 0.0086 15.9 0.0 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFO97577.1 - 1.9e-13 50.0 29.5 0.0045 16.9 2.4 7.7 6 2 0 6 6 6 5 Zinc ribbon domain XPA_N PF01286.13 KFO97577.1 - 2.3e-09 36.7 27.6 0.88 9.3 0.1 7.9 8 0 0 8 8 8 4 XPA protein N-terminal zf-RING_3 PF14369.1 KFO97577.1 - 5.5e-09 35.8 22.0 0.061 13.3 0.1 7.6 8 0 0 8 8 8 2 zinc-finger zf-LYAR PF08790.6 KFO97577.1 - 4.6e-06 26.2 26.6 0.085 12.5 0.1 7.6 8 0 0 8 8 8 1 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.2 KFO97577.1 - 0.00014 21.8 33.2 1.5 9.0 0.1 7.6 1 1 6 7 7 7 2 C2H2 type zinc-finger (2 copies) C1_3 PF07649.7 KFO97577.1 - 0.0003 20.7 18.7 14 5.7 0.0 7.7 8 0 0 8 8 8 0 C1-like domain FYDLN_acid PF09538.5 KFO97577.1 - 0.00057 20.4 9.9 17 6.0 0.4 6.6 2 1 3 5 5 5 0 Protein of unknown function (FYDLN_acid) TFIIS_C PF01096.13 KFO97577.1 - 0.00081 18.9 29.0 7.1 6.3 0.1 7.9 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) zf-met PF12874.2 KFO97577.1 - 0.0028 17.8 3.3 0.027 14.6 0.2 7.6 8 0 0 8 8 8 3 Zinc-finger of C2H2 type Elf1 PF05129.8 KFO97577.1 - 0.0076 15.9 17.7 0.35 10.5 0.3 4.5 1 1 4 5 5 5 2 Transcription elongation factor Elf1 like DZR PF12773.2 KFO97577.1 - 0.0086 15.8 24.3 0.67 9.8 2.5 5.0 1 1 2 3 3 3 1 Double zinc ribbon C1_4 PF07975.7 KFO97577.1 - 0.012 15.6 22.8 2.9 7.9 0.4 6.0 1 1 5 6 6 6 0 TFIIH C1-like domain zf-BED PF02892.10 KFO97577.1 - 0.013 15.2 52.5 0.31 10.8 1.9 8.1 2 2 6 8 8 8 0 BED zinc finger zf-trcl PF13451.1 KFO97577.1 - 0.013 15.1 23.2 24 4.6 1.1 7.3 7 1 0 7 7 7 0 Probable zinc-binding domain zf-HIT PF04438.11 KFO97577.1 - 0.015 14.9 31.9 2.7 7.6 0.2 7.7 8 0 0 8 8 8 0 HIT zinc finger zf-Di19 PF05605.7 KFO97577.1 - 0.018 15.1 31.9 0.52 10.4 0.9 5.9 2 2 3 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.14 KFO97577.1 - 0.019 14.6 21.2 0.64 9.7 0.6 4.8 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family BHD_2 PF10404.4 KFO97577.1 - 0.021 15.1 0.0 85 3.5 0.0 4.4 1 1 5 6 6 6 0 Rad4 beta-hairpin domain 2 zf-ribbon_3 PF13248.1 KFO97577.1 - 0.036 13.2 26.6 1.3 8.3 0.1 7.4 8 0 0 8 8 8 0 zinc-ribbon domain DUF2180 PF09947.4 KFO97577.1 - 0.061 13.0 15.9 2.4 8.0 0.1 5.3 1 1 3 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2180) RRN7 PF11781.3 KFO97577.1 - 0.37 10.3 16.2 8.7 5.9 0.0 6.5 8 0 0 8 8 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 GAGA PF09237.6 KFO97577.1 - 0.56 9.8 10.8 3.3 7.3 0.1 3.9 4 0 0 4 4 4 0 GAGA factor Zn_Tnp_IS1595 PF12760.2 KFO97577.1 - 1.1 9.1 42.6 0.89 9.4 3.1 6.6 2 2 5 7 7 6 0 Transposase zinc-ribbon domain Tmpp129 PF10272.4 KFO97577.1 - 1.1 7.9 5.0 0.37 9.4 0.1 2.3 2 1 0 2 2 2 0 Putative transmembrane protein precursor GF_recep_IV PF14843.1 KFO97577.1 - 3.3 7.3 16.8 0.61 9.7 0.7 3.4 1 1 1 2 2 2 0 Growth factor receptor domain IV DNA_RNApol_7kD PF03604.8 KFO97577.1 - 4.6 6.8 29.0 18 4.9 0.1 7.7 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit zf-UBP PF02148.14 KFO97577.1 - 4.7 7.4 34.2 5 7.3 0.4 6.3 1 1 2 3 3 2 0 Zn-finger in ubiquitin-hydrolases and other protein BolA PF01722.13 KFO97577.1 - 7 6.6 6.7 25 4.9 0.2 3.2 3 0 0 3 3 3 0 BolA-like protein TerY-C PF15616.1 KFO97577.1 - 7.9 6.4 13.5 3.4 7.5 1.0 3.2 1 1 4 5 5 5 0 TerY-C metal binding domain YhfH PF14149.1 KFO97577.1 - 8.1 6.3 28.9 10 6.0 0.1 7.5 8 0 0 8 8 8 0 YhfH-like protein LIM PF00412.17 KFO97577.1 - 8.8 6.4 26.1 3.5 7.7 0.3 6.1 1 1 5 7 7 6 0 LIM domain DUF2175 PF09943.4 KFO97577.1 - 9.5 6.3 8.7 20 5.2 0.0 5.0 7 0 0 7 7 6 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2H2 PF00096.21 KFO97578.1 - 4.1e-11 42.5 8.2 9.8e-06 25.6 0.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO97578.1 - 1e-08 35.0 7.8 3.9e-07 30.0 1.3 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFO97578.1 - 1.6e-05 24.6 4.7 0.00047 19.9 0.1 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFO97578.1 - 3.3e-05 23.8 9.6 0.007 16.6 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFO97578.1 - 0.0016 18.3 1.5 0.054 13.4 1.0 2.1 1 1 0 1 1 1 1 Zinc ribbon domain zf-Di19 PF05605.7 KFO97578.1 - 0.0061 16.6 4.6 0.063 13.4 0.3 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-IS66 PF13005.2 KFO97578.1 - 0.015 15.2 0.8 1.6 8.7 0.0 2.2 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-RING_3 PF14369.1 KFO97578.1 - 0.016 15.2 7.5 0.2 11.6 0.3 2.2 2 0 0 2 2 2 0 zinc-finger zf-C2H2_jaz PF12171.3 KFO97578.1 - 0.023 14.8 2.3 1.6 9.0 0.1 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KFO97578.1 - 0.077 12.6 2.5 0.83 9.3 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn_ribbon_recom PF13408.1 KFO97578.1 - 0.098 12.9 1.2 0.11 12.7 0.8 1.1 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain C1_4 PF07975.7 KFO97578.1 - 0.1 12.6 1.2 1.8 8.6 0.6 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain DZR PF12773.2 KFO97578.1 - 0.11 12.3 2.0 0.25 11.1 1.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon FYDLN_acid PF09538.5 KFO97578.1 - 0.19 12.3 0.5 0.49 11.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Opy2 PF09463.5 KFO97578.1 - 0.23 11.5 2.8 9 6.4 0.1 2.3 2 1 0 2 2 2 0 Opy2 protein zinc_ribbon_5 PF13719.1 KFO97578.1 - 0.3 10.7 3.2 2.7 7.6 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO97578.1 - 0.37 10.6 6.2 0.88 9.4 4.4 1.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFO97578.1 - 0.38 10.4 2.7 4.2 7.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TerY-C PF15616.1 KFO97578.1 - 0.42 10.5 2.0 0.51 10.2 1.4 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain Cys_rich_CPXG PF14255.1 KFO97578.1 - 0.56 10.0 0.2 0.56 10.0 0.2 2.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG OrfB_Zn_ribbon PF07282.6 KFO97578.1 - 0.78 9.4 3.0 4.6 6.9 2.1 2.1 1 1 0 1 1 1 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 KFO97578.1 - 0.96 9.1 6.3 4.5 7.0 0.5 2.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 PHD PF00628.24 KFO97578.1 - 1.3 8.7 6.2 1.5 8.6 4.3 1.1 1 0 0 1 1 1 0 PHD-finger ADK_lid PF05191.9 KFO97578.1 - 1.6 8.4 5.3 10 5.8 0.1 2.4 3 0 0 3 3 2 0 Adenylate kinase, active site lid zf-RING_2 PF13639.1 KFO97578.1 - 1.9 8.3 5.4 2.3 8.1 3.7 1.3 1 0 0 1 1 1 0 Ring finger domain zf-ribbon_3 PF13248.1 KFO97578.1 - 2.1 7.6 8.5 5.3 6.3 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF35_N PF12172.3 KFO97578.1 - 2.2 8.2 5.8 8.8 6.3 1.2 2.5 1 1 1 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-Mss51 PF13824.1 KFO97578.1 - 3.2 7.6 5.4 61 3.5 3.8 2.2 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CCHC_5 PF14787.1 KFO97578.1 - 3.5 7.1 5.7 2.5 7.6 0.7 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-ISL3 PF14690.1 KFO97578.1 - 8.2 6.5 8.4 16 5.5 1.7 2.3 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 7tm_4 PF13853.1 KFO97579.1 - 1.5e-44 151.2 14.5 1.5e-44 151.2 10.0 2.7 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFO97579.1 - 1.4e-31 109.5 24.1 2.2e-31 108.9 16.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFO97580.1 - 2.4e-45 153.8 11.4 2.4e-45 153.8 7.9 2.5 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO97580.1 - 1.4e-32 112.8 18.3 2e-32 112.3 12.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97580.1 - 0.011 14.8 20.9 0.053 12.6 13.2 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFO97581.1 - 2.6e-40 137.5 15.1 2.6e-40 137.5 10.5 2.4 3 1 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFO97581.1 - 2e-32 112.3 22.3 2e-32 112.3 15.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Peptidase_M2 PF01401.13 KFO97582.1 - 0 2072.1 18.9 0 1069.8 4.1 2.0 2 0 0 2 2 2 2 Angiotensin-converting enzyme Prominin PF05478.6 KFO97582.1 - 0.36 8.3 0.0 0.52 7.7 0.0 1.2 1 0 0 1 1 1 0 Prominin GETHR PF05671.6 KFO97585.1 - 9.9e-23 78.9 87.5 0.0043 16.1 7.7 7.7 1 1 7 8 8 8 8 GETHR pentapeptide repeat (5 copies) LIM PF00412.17 KFO97586.1 - 4.7e-12 45.7 11.0 5.1e-12 45.6 7.6 1.0 1 0 0 1 1 1 1 LIM domain Zn_Tnp_IS1595 PF12760.2 KFO97586.1 - 3.5 7.4 10.0 0.6 9.9 2.8 1.9 1 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-C3HC4_2 PF13923.1 KFO97587.1 - 3.3e-09 36.6 12.0 6.5e-09 35.6 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO97587.1 - 4.9e-09 35.7 9.3 9.2e-09 34.8 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 KFO97587.1 - 6.9e-09 35.1 2.3 6.9e-09 35.1 1.6 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 KFO97587.1 - 2e-07 30.7 10.5 3.6e-07 29.9 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFO97587.1 - 3.8e-06 26.4 11.2 9.4e-06 25.1 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO97587.1 - 5.4e-06 26.0 12.7 1.2e-05 24.9 8.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFO97587.1 - 0.00047 19.9 9.6 0.0014 18.5 6.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFO97587.1 - 0.0017 18.0 3.7 0.0054 16.4 2.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KFO97587.1 - 0.0038 16.7 5.3 0.011 15.2 3.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KFO97587.1 - 0.13 11.7 7.6 0.23 10.9 5.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.2 KFO97587.1 - 0.71 10.0 11.0 0.38 10.8 5.5 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger Pkinase PF00069.20 KFO97588.1 - 1.1e-33 116.5 0.0 1.6e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97588.1 - 3.8e-23 81.8 0.0 6.9e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO97588.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1682 PF07946.9 KFO97589.1 - 7.8e-105 350.2 7.0 1.1e-104 349.7 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) 7tm_2 PF00002.19 KFO97590.1 - 4.7e-82 274.7 14.4 5.9e-82 274.4 10.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFO97590.1 - 3e-15 55.9 6.4 6.4e-15 54.9 4.4 1.5 1 0 0 1 1 1 1 Hormone receptor domain EF-hand_6 PF13405.1 KFO97591.1 - 4.1e-09 35.5 0.0 0.00074 19.2 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KFO97591.1 - 1.1e-06 28.6 0.0 5.3e-05 23.2 0.0 2.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFO97591.1 - 0.00072 18.6 3.6 0.13 11.6 0.0 4.3 5 1 1 6 6 6 2 EF hand EF-hand_8 PF13833.1 KFO97591.1 - 0.18 11.4 4.0 4.7 6.9 0.0 3.3 2 1 1 3 3 3 0 EF-hand domain pair TPR_1 PF00515.23 KFO97592.1 - 3e-46 153.1 13.0 1e-09 37.5 0.2 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFO97592.1 - 3.6e-46 154.6 16.4 1.7e-13 49.9 1.2 7.5 4 1 4 8 8 8 6 TPR repeat TPR_2 PF07719.12 KFO97592.1 - 2.8e-33 111.1 14.7 6.5e-06 25.6 0.1 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat Apc3 PF12895.2 KFO97592.1 - 1.5e-32 111.5 25.6 5e-21 74.6 3.6 5.5 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFO97592.1 - 4.1e-29 100.3 9.2 5.8e-08 32.5 0.0 7.3 6 1 2 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFO97592.1 - 2.5e-27 92.5 5.1 6e-06 25.6 0.2 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFO97592.1 - 4.7e-25 85.6 8.8 0.00063 19.7 0.0 9.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97592.1 - 1.7e-23 82.7 1.6 8.9e-09 35.7 0.0 6.5 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97592.1 - 1.7e-21 76.2 5.8 0.0003 21.0 0.0 7.7 5 2 3 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFO97592.1 - 2.3e-16 58.7 0.0 0.07 13.8 0.0 8.7 4 1 5 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFO97592.1 - 8.9e-15 54.0 9.3 0.015 15.7 0.0 8.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFO97592.1 - 1.6e-09 37.4 0.0 0.0023 17.7 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFO97592.1 - 1.6e-09 36.8 1.3 0.23 11.3 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.5 KFO97592.1 - 2.1e-06 26.7 1.1 0.0022 16.8 0.0 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.1 KFO97592.1 - 1.5e-05 24.2 0.0 1.1 8.2 0.0 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFO97592.1 - 0.0046 16.8 0.3 19 5.3 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFO97592.1 - 0.014 15.5 0.7 0.23 11.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFO97592.1 - 0.014 15.3 0.1 0.17 11.7 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat PPTA PF01239.17 KFO97592.1 - 0.13 11.6 1.5 2.2 7.8 0.1 2.8 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat PEHE PF15275.1 KFO97593.1 - 2e-12 47.6 0.2 2e-12 47.6 0.2 3.4 2 1 1 3 3 3 1 PEHE domain Tubulin-binding PF00418.14 KFO97594.1 - 5.3e-62 205.1 37.5 6.2e-17 60.9 1.3 5.4 6 0 0 6 6 6 4 Tau and MAP protein, tubulin-binding repeat Mito_carr PF00153.22 KFO97595.1 - 2.8e-59 196.8 0.8 1.8e-21 75.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RIIa PF02197.12 KFO97595.1 - 0.23 10.9 0.6 0.39 10.1 0.4 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit HCO3_cotransp PF00955.16 KFO97596.1 - 1.8e-228 759.3 23.7 1.5e-136 456.0 7.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.8 KFO97596.1 - 4.5e-75 252.4 0.0 9.6e-75 251.4 0.0 1.5 1 1 0 1 1 1 1 Band 3 cytoplasmic domain HMG_box PF00505.14 KFO97597.1 - 3.5e-54 180.9 68.0 8.7e-18 64.3 5.2 7.3 7 0 0 7 7 7 6 HMG (high mobility group) box HMG_box_5 PF14887.1 KFO97597.1 - 3e-52 174.3 49.7 1.7e-49 165.5 4.1 6.0 5 1 1 6 6 6 3 HMG (high mobility group) box 5 HMG_box_2 PF09011.5 KFO97597.1 - 9.5e-29 99.5 60.1 2.7e-08 34.0 0.2 7.0 7 0 0 7 7 7 6 HMG-box domain DUF3106 PF11304.3 KFO97597.1 - 1.2 9.5 44.3 1.7 9.1 0.8 7.0 6 1 0 6 6 6 0 Protein of unknown function (DUF3106) DUF3175 PF11373.3 KFO97598.1 - 0.069 13.1 0.2 0.24 11.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3175) Perilipin PF03036.11 KFO97599.1 - 1.3e-164 547.6 16.7 1.5e-164 547.5 11.6 1.0 1 0 0 1 1 1 1 Perilipin family DUF2383 PF09537.5 KFO97599.1 - 0.0013 19.0 3.2 0.9 9.8 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF2383) Apc4 PF12896.2 KFO97599.1 - 0.019 14.2 5.0 0.31 10.3 0.3 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Tape_meas_lam_C PF09718.5 KFO97599.1 - 1.8 8.5 8.3 0.66 9.9 0.6 3.2 3 1 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Baculo_PEP_C PF04513.7 KFO97599.1 - 2.2 8.0 9.2 7.5 6.3 0.1 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DENN PF02141.16 KFO97600.1 - 1.2e-61 207.7 4.4 2.6e-61 206.5 3.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KFO97600.1 - 2.8e-21 75.3 1.1 6.5e-21 74.1 0.7 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KFO97600.1 - 4.4e-11 42.5 0.4 1.3e-10 41.0 0.3 1.9 1 0 0 1 1 1 1 uDENN domain PPR_2 PF13041.1 KFO97600.1 - 1e-05 25.4 0.1 0.00044 20.1 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 KFO97600.1 - 0.0064 16.6 0.1 0.092 13.0 0.0 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Papo_T_antigen PF02380.10 KFO97600.1 - 0.04 13.8 4.0 0.068 13.1 0.8 2.7 2 0 0 2 2 2 0 T-antigen specific domain PPR PF01535.15 KFO97600.1 - 0.15 12.0 0.0 0.48 10.5 0.0 1.9 1 0 0 1 1 1 0 PPR repeat Ribosomal_S6e PF01092.14 KFO97601.1 - 5.4e-64 213.5 0.1 1.1e-63 212.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Na_Ca_ex PF01699.19 KFO97602.1 - 3e-56 188.8 45.1 2.8e-30 104.7 11.0 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YEATS PF03366.11 KFO97603.1 - 3e-10 39.6 0.0 6.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 YEATS family DUF3028 PF11229.3 KFO97604.1 - 1.7e-255 848.8 9.7 2.7e-255 848.2 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3028) DUF3730 PF12530.3 KFO97604.1 - 3.2e-59 200.7 32.5 3.3e-53 181.0 2.7 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF3730) PTPLA PF04387.9 KFO97605.1 - 3.9e-41 140.2 8.7 5.7e-41 139.6 6.1 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Prion_bPrPp PF11587.3 KFO97605.1 - 4.6 7.0 5.3 21 4.8 0.0 2.8 3 0 0 3 3 3 0 Major prion protein bPrPp - N terminal Interferon PF00143.14 KFO97606.1 - 4.5e-36 124.1 7.6 5.1e-36 123.9 5.3 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain PDZ PF00595.19 KFO97607.1 - 4.9e-47 158.0 7.5 9.4e-17 60.9 0.2 3.4 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO97607.1 - 1.1e-16 60.5 3.9 6.1e-05 22.8 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.16 KFO97607.1 - 1.7e-12 47.1 0.1 3.6e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 KFO97607.1 - 7e-08 31.8 0.3 2.7e-06 26.7 0.0 3.4 4 0 0 4 4 4 1 Variant SH3 domain SH3_1 PF00018.23 KFO97607.1 - 8.8e-05 21.8 0.0 0.0029 16.9 0.0 3.2 2 0 0 2 2 2 1 SH3 domain Frataxin_Cyay PF01491.11 KFO97608.1 - 3e-34 117.1 0.0 3.3e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain PIP5K PF01504.13 KFO97609.1 - 1.7e-80 269.7 0.1 2.4e-80 269.2 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_S8 PF00082.17 KFO97610.1 - 2.2e-41 141.8 3.5 5e-40 137.4 2.4 2.3 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFO97610.1 - 6.1e-32 109.2 0.0 1.3e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain GF_recep_IV PF14843.1 KFO97610.1 - 8e-14 51.3 90.1 9.4e-11 41.4 25.1 3.8 1 1 2 3 3 3 3 Growth factor receptor domain IV PLAC PF08686.6 KFO97610.1 - 3.1e-13 49.7 8.3 3.1e-13 49.7 5.8 4.8 5 0 0 5 5 5 1 PLAC (protease and lacunin) domain VSP PF03302.8 KFO97610.1 - 3.8e-07 29.0 79.2 0.0015 17.2 10.8 5.5 2 1 4 6 6 6 4 Giardia variant-specific surface protein DUF4215 PF13948.1 KFO97610.1 - 0.0065 16.6 15.7 0.0065 16.6 10.9 6.9 5 2 1 6 6 6 1 Domain of unknown function (DUF4215) Ank_2 PF12796.2 KFO97612.1 - 1.6e-34 118.1 10.0 2.6e-18 66.1 0.3 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFO97612.1 - 1.5e-23 82.2 3.7 6.5e-11 42.1 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFO97612.1 - 5.3e-19 67.0 1.2 8.4e-08 31.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFO97612.1 - 7.9e-17 61.2 0.8 1.1e-08 35.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.23 KFO97612.1 - 3.7e-15 55.0 0.0 6.7e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.1 KFO97612.1 - 7.7e-15 53.5 0.3 0.0018 18.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat SH3_9 PF14604.1 KFO97612.1 - 2.5e-13 49.3 0.0 4.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO97612.1 - 3.2e-12 45.7 0.0 6.7e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_18 PF13238.1 KFO97613.1 - 1e-12 48.4 0.0 1.8e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFO97613.1 - 0.0015 19.2 0.2 0.0043 17.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain N2227 PF07942.7 KFO97614.1 - 6.3e-112 372.9 0.2 7.5e-112 372.7 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.7 KFO97614.1 - 0.027 14.9 0.0 0.09 13.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 KFO97614.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RhoGAP PF00620.22 KFO97614.1 - 0.043 13.4 0.5 1.4 8.5 0.2 2.2 1 1 1 2 2 2 0 RhoGAP domain Methyltransf_24 PF13578.1 KFO97614.1 - 0.062 14.1 0.0 0.15 12.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFO97614.1 - 0.067 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ion_trans PF00520.26 KFO97615.1 - 1.9e-06 27.2 12.9 6.4e-06 25.5 8.9 2.0 1 1 0 1 1 1 1 Ion transport protein zf-C4 PF00105.13 KFO97616.1 - 2.1e-33 114.3 12.3 5e-33 113.1 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFO97616.1 - 4.7e-29 100.9 2.0 4.7e-29 100.9 1.4 2.0 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor Yae1_N PF09811.4 KFO97617.1 - 1.9e-17 62.5 52.8 1.5e+04 -13.4 36.6 4.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.4 KFO97618.1 - 2.6e-20 71.6 64.2 1.5e+04 -24.9 44.5 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Annexin PF00191.15 KFO97619.1 - 4.3e-87 286.0 16.0 1e-24 86.1 0.4 4.1 4 0 0 4 4 4 4 Annexin DUF3186 PF11382.3 KFO97619.1 - 0.059 12.4 2.5 0.091 11.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DrrA_P4M PF14860.1 KFO97619.1 - 0.11 12.2 3.7 4.3 7.1 0.1 2.8 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Cyc-maltodext_C PF10438.4 KFO97619.1 - 0.11 12.5 0.1 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain Aldedh PF00171.17 KFO97620.1 - 1e-186 620.7 0.0 1.2e-186 620.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFO97620.1 - 0.08 12.1 0.0 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TMC PF07810.8 KFO97621.1 - 1.1e-40 138.4 2.8 1.1e-40 138.4 1.9 2.0 2 0 0 2 2 2 1 TMC domain Hid1 PF12722.2 KFO97621.1 - 0.003 15.3 0.5 0.0045 14.7 0.4 1.4 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 KFO97621.1 - 0.31 10.1 15.5 0.46 9.5 10.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein zf-A20 PF01754.11 KFO97622.1 - 7.7e-13 47.7 7.7 2.2e-12 46.3 5.3 1.9 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 KFO97622.1 - 1.6e-12 47.1 6.9 1.6e-12 47.1 4.8 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger zf-C3HC4_3 PF13920.1 KFO97622.1 - 6.1 6.5 9.0 3.6 7.3 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Amidohydro_1 PF01979.15 KFO97623.1 - 2.3e-43 149.1 0.0 2.8e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFO97623.1 - 1.3e-06 28.6 0.0 0.0057 16.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KFO97623.1 - 7.1e-05 22.5 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFO97623.1 - 0.00013 21.3 0.2 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF2039 PF10217.4 KFO97624.1 - 6.2e-25 87.0 10.7 6.7e-25 86.9 7.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.4 KFO97624.1 - 0.12 12.7 11.6 0.097 13.0 6.6 1.7 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DUF2256 PF10013.4 KFO97624.1 - 0.17 11.6 0.2 0.17 11.6 0.2 3.2 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-dskA_traR PF01258.12 KFO97624.1 - 0.29 10.9 0.2 0.29 10.9 0.1 3.4 2 1 2 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger ADK_lid PF05191.9 KFO97624.1 - 0.29 10.8 12.6 2.7 7.7 0.0 3.2 2 1 1 3 3 3 0 Adenylate kinase, active site lid Stc1 PF12898.2 KFO97624.1 - 0.31 11.1 7.8 0.95 9.5 5.6 1.7 1 1 0 1 1 1 0 Stc1 domain Transferrin PF00405.12 KFO97624.1 - 0.72 8.6 4.7 0.61 8.9 0.2 1.9 1 1 1 2 2 2 0 Transferrin Zn-ribbon_8 PF09723.5 KFO97624.1 - 1.1 9.3 10.4 0.42 10.5 0.5 2.8 1 1 2 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.7 KFO97624.1 - 5.3 6.9 10.1 9.2 6.1 4.2 2.0 1 1 0 1 1 1 0 zinc-ribbons zf-RING_5 PF14634.1 KFO97624.1 - 6.2 6.6 14.8 0.23 11.2 1.8 2.8 2 1 1 3 3 3 0 zinc-RING finger domain Abhydrolase_5 PF12695.2 KFO97625.1 - 3.7e-29 101.3 0.0 5.2e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFO97625.1 - 1.3e-14 54.6 0.1 8.6e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFO97625.1 - 3.1e-08 33.1 0.0 4.8e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFO97625.1 - 1.7e-06 27.7 0.0 0.016 14.8 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 KFO97625.1 - 1.9e-05 24.0 0.0 3.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 KFO97625.1 - 0.0042 16.5 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) UPF0227 PF05728.7 KFO97625.1 - 0.0044 16.7 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DUF818 PF05677.7 KFO97625.1 - 0.018 13.7 0.1 0.026 13.2 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 KFO97625.1 - 0.027 13.9 0.0 0.083 12.3 0.0 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase RNA_ligase PF09414.5 KFO97625.1 - 0.063 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA ligase Hydrolase_4 PF12146.3 KFO97625.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase G8 PF10162.4 KFO97626.1 - 1.9e-25 89.0 0.0 4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 G8 domain PADR1 PF08063.7 KFO97626.1 - 0.11 11.9 1.9 10 5.5 0.0 3.2 3 0 0 3 3 3 0 PADR1 (NUC008) domain Ion_trans PF00520.26 KFO97627.1 - 6.8e-11 41.7 12.1 6.8e-11 41.7 8.4 1.9 2 1 0 2 2 2 1 Ion transport protein zf-C2H2 PF00096.21 KFO97628.1 - 2.4e-12 46.4 11.8 4.6e-06 26.6 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO97628.1 - 3e-11 43.0 8.6 4.1e-09 36.2 2.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO97628.1 - 1.2e-10 40.8 11.0 4.6e-05 23.4 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 KFO97628.1 - 0.00031 20.4 2.6 0.0084 15.8 1.8 2.0 1 1 1 2 2 2 1 BED zinc finger zf-met PF12874.2 KFO97628.1 - 0.0004 20.4 1.3 0.038 14.2 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFO97628.1 - 0.0016 18.2 3.6 0.16 11.9 0.9 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger Rad50_zn_hook PF04423.9 KFO97628.1 - 0.0081 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-TRAF PF02176.13 KFO97628.1 - 0.0088 16.4 1.0 0.011 16.1 0.7 1.1 1 0 0 1 1 1 1 TRAF-type zinc finger zf-Di19 PF05605.7 KFO97628.1 - 0.022 14.8 2.8 0.044 13.9 1.9 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFO97628.1 - 0.033 14.3 3.1 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFO97628.1 - 0.046 13.8 0.8 0.066 13.3 0.6 1.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Tmpp129 PF10272.4 KFO97628.1 - 0.054 12.2 1.2 0.061 12.0 0.8 1.0 1 0 0 1 1 1 0 Putative transmembrane protein precursor PyrI_C PF02748.10 KFO97628.1 - 0.055 12.9 0.2 0.068 12.6 0.1 1.1 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_Tnp_IS1 PF03811.8 KFO97628.1 - 0.062 12.8 0.9 0.11 11.9 0.6 1.5 1 0 0 1 1 1 0 InsA N-terminal domain zf-Sec23_Sec24 PF04810.10 KFO97628.1 - 0.085 12.4 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C2HC_2 PF13913.1 KFO97628.1 - 0.11 12.1 2.6 0.81 9.4 0.5 2.2 1 1 1 2 2 2 0 zinc-finger of a C2HC-type RRN7 PF11781.3 KFO97628.1 - 0.15 11.5 1.1 0.23 11.0 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2225 PF09986.4 KFO97628.1 - 0.18 11.2 1.0 0.25 10.7 0.2 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.1 KFO97628.1 - 5.5 7.4 5.8 15 6.0 0.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain MAM PF00629.18 KFO97629.1 - 3.5e-135 446.1 0.1 4.4e-45 153.3 0.0 4.0 4 0 0 4 4 4 4 MAM domain PPTA PF01239.17 KFO97630.1 - 7.3e-30 101.0 9.7 3.5e-09 35.5 0.0 6.4 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Cleaved_Adhesin PF07675.6 KFO97630.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Cleaved Adhesin Domain PID PF00640.18 KFO97631.1 - 1.4e-50 170.9 1.1 2.8e-50 169.9 0.8 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 KFO97631.1 - 9.7e-32 108.9 10.3 5.1e-17 61.8 0.7 3.2 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO97631.1 - 1.3e-07 31.4 0.1 1.7e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.1 KFO97631.1 - 0.023 14.4 0.2 2.8 7.8 0.0 3.2 3 0 0 3 3 3 0 Tricorn protease PDZ domain Flavokinase PF01687.12 KFO97632.1 - 2.9e-29 101.4 0.0 3.1e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase BNIP2 PF12496.3 KFO97633.1 - 3.5e-45 153.2 3.4 4.6e-45 152.8 2.4 1.1 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 KFO97633.1 - 7.4e-30 103.8 0.1 9.9e-30 103.4 0.1 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFO97633.1 - 5.8e-10 38.8 0.5 8.9e-10 38.2 0.3 1.3 1 1 0 1 1 1 1 CRAL/TRIO domain RRN3 PF05327.6 KFO97633.1 - 0.4 8.7 3.3 6.6 4.7 0.7 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DHHA2 PF02833.9 KFO97634.1 - 0.0099 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain FUR PF01475.14 KFO97634.1 - 0.019 14.8 0.1 0.15 12.0 0.1 2.2 2 1 0 2 2 2 0 Ferric uptake regulator family Ste50p-SAM PF09235.5 KFO97634.1 - 0.038 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Ste50p, sterile alpha motif K-box PF01486.12 KFO97634.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 K-box region G-alpha PF00503.15 KFO97635.1 - 1.3e-118 396.0 2.0 1.5e-118 395.9 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFO97635.1 - 7.4e-12 44.8 0.2 3.6e-11 42.6 0.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFO97635.1 - 0.13 12.7 0.0 28 5.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Aminotran_5 PF00266.14 KFO97636.1 - 4.2e-59 200.1 0.0 4.7e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V EGF_alliinase PF04863.8 KFO97636.1 - 0.11 12.4 0.4 0.25 11.3 0.3 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain Lipase_GDSL_2 PF13472.1 KFO97637.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TLE_N PF03920.10 KFO97638.1 - 3.8e-37 127.1 6.4 5.8e-37 126.5 4.4 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 KFO97638.1 - 9.3e-32 107.7 21.7 3.8e-08 32.8 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFO97638.1 - 0.031 12.5 0.0 1.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Transketolase_N PF00456.16 KFO97638.1 - 0.042 12.6 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain PQQ_3 PF13570.1 KFO97638.1 - 0.14 12.4 0.9 15 6.0 0.0 4.0 3 1 1 4 4 4 0 PQQ-like domain TLE_N PF03920.10 KFO97639.1 - 2e-53 179.8 9.5 3e-53 179.2 6.6 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 KFO97639.1 - 1.3e-30 104.1 23.4 4e-08 32.8 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFO97639.1 - 0.061 11.6 0.0 1.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Transketolase_N PF00456.16 KFO97639.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Ras PF00071.17 KFO97640.1 - 6.2e-50 168.7 0.7 9.1e-50 168.2 0.0 1.6 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFO97640.1 - 1.6e-20 73.7 0.7 4.8e-20 72.2 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFO97640.1 - 4.2e-16 58.6 1.2 7.8e-16 57.7 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFO97640.1 - 2e-07 30.9 0.3 7.1e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFO97640.1 - 0.00013 21.4 0.5 0.0004 19.8 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFO97640.1 - 0.012 14.8 3.9 0.037 13.1 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF3227 PF11537.3 KFO97640.1 - 0.041 14.0 2.1 0.34 11.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3227) Reo_sigmaC PF04582.7 KFO97640.1 - 0.062 12.4 2.7 0.099 11.8 1.4 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein AAA_25 PF13481.1 KFO97640.1 - 0.17 11.3 1.6 0.54 9.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.7 KFO97640.1 - 2.3 7.9 33.7 1.3 8.7 12.2 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 KFO97640.1 - 2.4 8.0 33.7 0.96 9.3 11.6 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FERM_M PF00373.13 KFO97641.1 - 5.8e-19 68.5 0.2 1.4e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFO97641.1 - 1.4e-16 60.2 0.1 3.5e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.6 KFO97641.1 - 2.7e-16 59.0 3.6 5e-16 58.2 2.5 1.5 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_C PF09380.5 KFO97641.1 - 3.3e-16 59.2 0.2 7.1e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain SKI PF01202.17 KFO97642.1 - 1.3e-07 31.6 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase ubiquitin PF00240.18 KFO97643.1 - 4.8e-13 48.3 0.8 8e-13 47.5 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KFO97643.1 - 1e-06 28.4 0.3 2.9e-06 26.9 0.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 KFO97643.1 - 0.00019 21.0 0.1 0.00035 20.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KFO97643.1 - 0.015 15.1 0.2 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Clathrin-link PF09268.5 KFO97643.1 - 0.038 13.0 14.8 3.1 6.9 0.1 5.6 5 0 0 5 5 5 0 Clathrin, heavy-chain linker CUE PF02845.11 KFO97643.1 - 0.04 13.3 0.6 0.16 11.5 0.0 2.5 2 0 0 2 2 2 0 CUE domain TcdB_N PF12918.2 KFO97644.1 - 1.1 9.3 12.4 1.6 8.8 0.7 3.6 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Pox_A_type_inc PF04508.7 KFO97644.1 - 5.7 6.9 12.7 9.6 6.2 0.0 4.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Kinesin PF00225.18 KFO97645.1 - 1.4e-110 369.2 1.0 1.4e-110 369.2 0.7 3.1 3 0 0 3 3 3 1 Kinesin motor domain DUF2419 PF10343.4 KFO97646.1 - 8.6e-88 294.3 0.0 9.6e-88 294.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) KH_1 PF00013.24 KFO97647.1 - 8e-44 147.1 13.9 3.7e-19 68.1 0.9 4.3 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 KFO97647.1 - 5.3e-34 115.2 11.0 7.3e-13 47.8 2.5 3.7 3 0 0 3 3 3 3 KH domain ROKNT PF08067.6 KFO97647.1 - 6.4e-23 80.3 9.8 1e-22 79.6 6.8 1.3 1 0 0 1 1 1 1 ROKNT (NUC014) domain KH_2 PF07650.12 KFO97647.1 - 3.5e-15 55.3 5.3 0.00057 19.3 0.0 4.0 4 0 0 4 4 4 3 KH domain KH_4 PF13083.1 KFO97647.1 - 5.2e-08 32.4 6.1 7e-06 25.5 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KFO97647.1 - 0.00057 19.6 5.2 0.74 9.6 0.1 3.8 3 1 1 4 4 4 2 NusA-like KH domain Phi-29_GP3 PF05435.6 KFO97647.1 - 0.029 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 DUF1767 PF08585.7 KFO97648.1 - 2.3e-24 85.4 0.4 5.3e-24 84.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Nucleos_tra2_C PF07662.8 KFO97649.1 - 1.5e-71 240.1 5.6 2.7e-71 239.3 3.9 1.4 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KFO97649.1 - 2.4e-16 59.8 2.1 2.4e-16 59.8 1.4 3.4 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KFO97649.1 - 2.3e-08 33.8 7.1 2.3e-08 33.8 4.9 3.6 3 1 0 3 3 3 1 Nucleoside recognition Pkinase_Tyr PF07714.12 KFO97650.1 - 3.6e-98 327.7 0.0 4.9e-98 327.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO97650.1 - 1.8e-50 171.4 0.0 2.6e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFO97650.1 - 2.9e-23 81.5 0.2 4.9e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97650.1 - 1.1e-09 38.2 2.2 1.6e-05 24.9 0.2 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFO97650.1 - 1.3e-08 35.2 8.8 6.6e-08 32.9 2.5 2.8 2 0 0 2 2 2 1 Immunoglobulin domain LRR_8 PF13855.1 KFO97650.1 - 2.3e-07 30.4 1.0 6.9e-07 28.9 0.7 1.9 1 0 0 1 1 1 1 Leucine rich repeat ig PF00047.20 KFO97650.1 - 2.4e-07 30.7 6.6 1.2e-05 25.3 0.4 2.9 3 0 0 3 3 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFO97650.1 - 0.00025 20.8 0.7 0.22 11.4 0.1 2.8 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFO97650.1 - 0.00093 19.0 0.7 0.017 15.0 0.2 2.8 1 1 0 1 1 1 1 Immunoglobulin V-set domain Kinase-like PF14531.1 KFO97650.1 - 0.0071 15.3 0.1 0.029 13.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like LRR_1 PF00560.28 KFO97650.1 - 0.023 14.6 3.3 0.041 13.9 0.4 3.1 3 0 0 3 3 1 0 Leucine Rich Repeat Herpes_gE PF02480.11 KFO97650.1 - 0.033 12.4 0.0 1.4 7.1 0.0 2.7 2 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E LRR_4 PF12799.2 KFO97650.1 - 0.073 12.7 3.0 0.098 12.3 0.2 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) zf-RING_4 PF14570.1 KFO97651.1 - 6.4e-20 70.4 12.0 1.2e-19 69.6 8.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 KFO97651.1 - 4.1e-06 26.5 0.0 8.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO97651.1 - 8.4e-06 25.3 0.0 1.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KFO97651.1 - 1.3e-05 24.7 6.9 2.5e-05 23.8 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 KFO97651.1 - 5.1e-05 23.1 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 KFO97651.1 - 0.028 14.1 5.1 0.074 12.8 3.5 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 KFO97651.1 - 0.029 14.0 9.9 0.062 12.9 6.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO97651.1 - 0.036 14.0 11.3 0.08 12.9 7.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO97651.1 - 0.25 11.1 8.8 0.48 10.1 6.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF3414 PF11894.3 KFO97652.1 - 0 1736.6 13.7 0 1736.4 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Arf PF00025.16 KFO97653.1 - 1e-75 252.7 0.1 1.2e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFO97653.1 - 1.7e-13 50.2 0.0 1.9e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFO97653.1 - 1.4e-11 43.9 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFO97653.1 - 2.7e-11 42.7 1.2 1.1e-07 30.9 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFO97653.1 - 3.5e-11 42.6 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFO97653.1 - 5e-09 36.6 0.0 6.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFO97653.1 - 7.6e-06 25.8 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFO97653.1 - 0.00019 20.9 0.3 0.0023 17.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KFO97653.1 - 0.00078 18.3 0.6 0.035 12.8 0.1 2.6 2 1 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 KFO97653.1 - 0.014 15.6 0.3 0.081 13.2 0.2 1.9 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 KFO97653.1 - 0.022 14.0 0.9 0.17 11.1 0.6 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KFO97653.1 - 0.045 13.2 0.3 1.7 8.1 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KFO97653.1 - 0.052 12.9 0.2 4.1 6.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFO97653.1 - 0.14 12.0 0.1 0.72 9.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain DRIM PF07539.7 KFO97654.1 - 2.4e-48 163.1 1.9 5.4e-48 161.9 0.3 2.6 2 0 0 2 2 2 1 Down-regulated in metastasis Arm PF00514.18 KFO97654.1 - 0.37 10.6 4.6 30 4.6 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Anoctamin PF04547.7 KFO97655.1 - 8.3e-157 522.4 11.6 1e-156 522.1 8.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GAS2 PF02187.12 KFO97656.1 - 5.1e-29 99.8 0.0 1e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 KFO97656.1 - 3e-07 30.4 0.0 4.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Hormone_recep PF00104.25 KFO97657.1 - 4.7e-33 114.0 1.7 8.3e-33 113.2 1.2 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO97657.1 - 7.4e-29 99.7 14.7 7.4e-29 99.7 10.2 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Pkinase PF00069.20 KFO97658.1 - 1.9e-25 89.4 0.0 3.5e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97658.1 - 5.7e-16 58.3 0.0 2.9e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Strep_67kDa_ant PF06100.6 KFO97658.1 - 0.022 13.1 0.6 0.033 12.5 0.4 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DEP PF00610.16 KFO97659.1 - 7.7e-18 64.0 0.7 5.5e-16 58.0 0.1 2.7 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3883 PF13020.1 KFO97659.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) Actin PF00022.14 KFO97660.1 - 5.9e-79 265.3 0.0 6.8e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Actin Aldo_ket_red PF00248.16 KFO97661.1 - 6.4e-58 195.8 0.0 7.5e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KFO97662.1 - 8e-58 195.4 0.0 9.3e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Leader_Trp PF08255.6 KFO97662.1 - 0.097 12.3 0.2 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Trp-operon Leader Peptide Aldo_ket_red PF00248.16 KFO97663.1 - 2.1e-53 181.0 0.0 2.4e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family His_Phos_1 PF00300.17 KFO97664.1 - 4.7e-43 147.0 0.0 6.4e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Caldesmon PF02029.10 KFO97666.1 - 5.2e-196 651.8 209.7 3.9e-145 484.0 56.2 3.6 1 1 2 3 3 3 2 Caldesmon Aldo_ket_red PF00248.16 KFO97667.1 - 7.6e-61 205.4 0.0 8.7e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.17 KFO97668.1 - 2.5e-26 92.0 0.0 2.7e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97668.1 - 4.5e-11 43.2 0.0 5.5e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO97668.1 - 0.0037 16.5 0.0 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1830 PF08865.6 KFO97669.1 - 0.074 12.6 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Y_phosphatase PF00102.22 KFO97670.1 - 9e-85 283.7 1.9 2.2e-84 282.4 1.3 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase fn3 PF00041.16 KFO97670.1 - 8.9e-29 99.4 17.1 5.3e-09 36.0 0.5 6.1 5 0 0 5 5 5 5 Fibronectin type III domain PTPlike_phytase PF14566.1 KFO97670.1 - 0.00012 22.1 0.1 0.00036 20.5 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 KFO97670.1 - 0.00019 21.0 0.0 0.00051 19.6 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFO97670.1 - 0.00027 21.2 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTB PF08416.8 KFO97671.1 - 3.8e-53 178.8 1.4 7.1e-53 177.9 1.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.23 KFO97671.1 - 5.7e-10 38.4 0.1 1.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFO97671.1 - 1.1e-06 28.0 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.18 KFO97671.1 - 2.3e-06 27.6 1.2 5.3e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.12 KFO97671.1 - 1.7e-05 24.1 0.0 3.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFO97671.1 - 0.00058 20.0 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain SAM_PNT PF02198.11 KFO97671.1 - 0.078 12.7 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DeoC PF01791.4 KFO97672.1 - 9.7e-39 133.0 0.0 1.1e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase PTR2 PF00854.16 KFO97673.1 - 1.1e-27 96.8 13.8 8.6e-17 60.9 3.6 2.2 1 1 1 2 2 2 2 POT family MAPEG PF01124.13 KFO97674.1 - 9.3e-25 86.7 0.9 1.1e-24 86.5 0.6 1.0 1 0 0 1 1 1 1 MAPEG family LIM PF00412.17 KFO97675.1 - 1.1e-30 105.4 22.3 2.4e-15 56.3 5.8 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 KFO97675.1 - 3.9 7.5 22.7 0.35 10.8 4.9 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Ras PF00071.17 KFO97676.1 - 2.9e-19 69.0 0.0 3.9e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97676.1 - 2.2e-07 31.4 0.0 5.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PUB PF09409.5 KFO97676.1 - 0.11 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 PUB domain Taxilin PF09728.4 KFO97677.1 - 2e-116 388.3 71.8 2.3e-116 388.2 49.8 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein PMT_C PF11647.3 KFO97677.1 - 0.038 13.6 1.3 0.21 11.2 0.9 2.4 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 HTH_26 PF13443.1 KFO97677.1 - 0.2 11.8 3.1 0.8 9.9 0.0 3.4 4 1 0 4 4 4 0 Cro/C1-type HTH DNA-binding domain UPF0270 PF06794.7 KFO97677.1 - 0.8 9.5 11.4 1.8 8.3 0.3 3.9 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0270) WD40 PF00400.27 KFO97678.1 - 6.9e-38 127.2 13.0 6.3e-09 35.3 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFO97678.1 - 4.2e-30 103.4 0.8 1.2e-29 101.9 0.6 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 KFO97678.1 - 3e-05 23.8 0.3 0.016 14.9 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A EF-hand_4 PF12763.2 KFO97679.1 - 1.6e-12 47.0 0.0 3.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KFO97679.1 - 0.0098 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFO97679.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KFO97679.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 EF hand NHS PF15273.1 KFO97680.1 - 1.3e-228 760.9 50.7 1.3e-228 760.9 35.1 2.6 2 1 0 2 2 2 1 NHS-like BEN PF10523.4 KFO97681.1 - 3.3e-28 97.5 0.3 1.2e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 BEN domain Pkinase PF00069.20 KFO97683.1 - 1.8e-73 246.8 0.0 2.9e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97683.1 - 1.6e-34 119.1 0.0 2.7e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO97683.1 - 0.035 13.0 0.1 1.8 7.4 0.0 2.2 1 1 0 2 2 2 0 Kinase-like APH PF01636.18 KFO97683.1 - 0.22 11.2 1.4 1.8 8.2 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family F5_F8_type_C PF00754.20 KFO97684.1 - 2e-32 111.7 0.4 2.6e-32 111.3 0.3 1.1 1 0 0 1 1 1 1 F5/8 type C domain Metallophos PF00149.23 KFO97685.1 - 1.8e-38 131.9 0.3 3.1e-38 131.2 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 KFO97685.1 - 2e-16 57.9 0.1 1.5e-05 23.9 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFO97685.1 - 9.4e-13 48.1 0.4 2.2e-09 37.2 0.2 2.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFO97685.1 - 9.9e-11 40.5 0.0 0.0027 17.4 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFO97685.1 - 7.9e-10 38.2 0.6 0.0003 20.3 0.0 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFO97685.1 - 1.6e-08 33.4 0.4 0.00042 19.5 0.0 2.7 2 0 0 2 2 2 2 EF hand PPP5 PF08321.7 KFO97685.1 - 3.1e-07 30.3 0.0 7.8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region IQ PF00612.22 KFO97685.1 - 0.11 12.1 0.7 0.24 11.1 0.5 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif EF-hand_4 PF12763.2 KFO97685.1 - 0.44 10.3 3.1 1.5 8.6 0.3 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Glyco_hydro_15 PF00723.16 KFO97686.1 - 6e-182 605.1 0.0 7.2e-182 604.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 7tm_2 PF00002.19 KFO97687.1 - 5.7e-57 192.5 22.1 1.3e-56 191.4 15.3 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFO97687.1 - 2.6e-14 53.0 4.1 8e-14 51.4 2.9 1.9 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain FA_desaturase PF00487.19 KFO97687.1 - 0.28 10.5 11.6 0.38 10.1 0.7 2.2 2 0 0 2 2 2 0 Fatty acid desaturase E1_dh PF00676.15 KFO97688.1 - 6.1e-123 409.3 0.0 7.1e-123 409.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFO97688.1 - 0.0017 17.9 0.3 0.0032 17.0 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KFO97688.1 - 0.0043 16.0 0.0 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase SH3_9 PF14604.1 KFO97689.1 - 2.4e-54 180.6 4.5 8e-18 63.7 0.1 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFO97689.1 - 1.9e-43 145.5 7.7 3.2e-15 55.2 0.3 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 KFO97689.1 - 3.4e-43 144.9 4.7 1.7e-13 49.8 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain XFP PF03894.10 KFO97689.1 - 0.001 18.7 0.0 2.9 7.4 0.0 3.0 3 0 0 3 3 3 2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Tmemb_cc2 PF10267.4 KFO97689.1 - 0.0022 16.6 0.8 0.0037 15.9 0.6 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein THRAP3_BCLAF1 PF15440.1 KFO97690.1 - 4.2e-75 253.7 7.2 4.6e-75 253.5 5.0 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family Gtr1_RagA PF04670.7 KFO97690.1 - 0.031 13.3 0.1 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MAP7 PF05672.6 KFO97691.1 - 2.5e-52 176.7 80.6 2.5e-52 176.7 55.8 2.9 3 0 0 3 3 3 1 MAP7 (E-MAP-115) family eIF-1a PF01176.14 KFO97692.1 - 1.8e-27 94.5 0.2 2.3e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 KFO97693.1 - 1.3e-143 476.8 0.0 2.4e-71 239.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97693.1 - 1.3e-77 260.3 0.0 8.1e-42 143.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFO97693.1 - 4e-15 55.5 0.1 1.6e-08 33.8 0.0 2.9 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 KFO97693.1 - 1.1e-10 40.9 0.0 1.7e-05 23.9 0.0 2.9 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KFO97693.1 - 3.3e-08 33.9 0.3 7.2e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain YrbL-PhoP_reg PF10707.4 KFO97693.1 - 3.1e-06 26.6 0.0 0.0047 16.2 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL APH PF01636.18 KFO97693.1 - 6.7e-06 26.0 0.0 0.099 12.3 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family tRNA-synt_1f PF01921.13 KFO97693.1 - 0.011 14.4 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) RIO1 PF01163.17 KFO97693.1 - 0.023 14.0 0.3 1.4 8.2 0.0 2.6 3 0 0 3 3 3 0 RIO1 family DUF1170 PF06663.8 KFO97694.1 - 8.4e-80 267.1 5.4 8.4e-80 267.1 3.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.4 KFO97694.1 - 3.5e-44 148.7 1.7 7.6e-44 147.6 0.1 2.4 3 0 0 3 3 3 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.25 KFO97694.1 - 6.5e-15 55.0 2.3 1.9e-14 53.5 0.2 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) PH PF00169.24 KFO97694.1 - 1.2e-13 51.1 6.4 1.9e-13 50.5 2.4 2.7 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 KFO97694.1 - 5.1e-10 39.0 0.6 3.7e-09 36.2 0.2 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 KFO97694.1 - 5.5e-09 36.0 0.1 1.6e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PH_9 PF15410.1 KFO97694.1 - 0.00054 20.1 3.2 0.094 12.8 2.0 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain PDZ_2 PF13180.1 KFO97694.1 - 0.0034 17.2 0.2 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 PDZ domain ATG11 PF10377.4 KFO97694.1 - 0.029 14.2 0.5 0.087 12.7 0.3 1.8 1 0 0 1 1 1 0 Autophagy-related protein 11 PH_11 PF15413.1 KFO97694.1 - 0.69 10.1 14.4 0.063 13.5 4.9 3.1 2 2 0 2 2 2 0 Pleckstrin homology domain Kelch_1 PF01344.20 KFO97695.1 - 1.3e-40 136.6 0.0 1.1e-09 37.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFO97695.1 - 1.2e-33 113.8 0.9 1.4e-08 34.5 0.0 6.4 2 1 4 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KFO97695.1 - 8.4e-27 92.6 0.0 5.8e-05 23.1 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFO97695.1 - 1.5e-26 92.5 0.6 3.4e-26 91.4 0.4 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 KFO97695.1 - 4.8e-25 87.0 0.1 8.2e-05 22.2 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFO97695.1 - 3.9e-15 54.9 1.0 0.00031 20.3 0.0 5.5 4 2 0 4 4 4 4 Kelch motif Kelch_5 PF13854.1 KFO97695.1 - 8.4e-11 41.5 1.9 0.0082 16.0 0.0 5.5 5 0 0 5 5 5 3 Kelch motif BACK PF07707.10 KFO97695.1 - 5.1e-10 39.1 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Chisel PF15355.1 KFO97696.1 - 1.3e-41 140.5 3.8 1.4e-41 140.4 2.6 1.0 1 0 0 1 1 1 1 Stretch-responsive small skeletal muscle X protein, Chisel Peptidase_M50 PF02163.17 KFO97697.1 - 1.8e-25 89.0 0.0 1.9e-24 85.6 0.0 2.2 2 1 0 2 2 2 1 Peptidase family M50 PDZ_2 PF13180.1 KFO97697.1 - 0.0045 16.8 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Spermine_synth PF01564.12 KFO97698.1 - 8.4e-61 205.0 0.1 1e-60 204.7 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Peptidase_M13_N PF05649.8 KFO97699.1 - 7.2e-116 387.4 2.0 9.3e-116 387.0 1.4 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFO97699.1 - 1.6e-56 190.7 0.0 2.8e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF4589 PF15252.1 KFO97701.1 - 3.1e-70 236.4 0.2 3.5e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) BUD22 PF09073.5 KFO97702.1 - 6.5e-09 35.3 11.5 6.5e-09 35.3 8.0 2.6 1 1 1 2 2 2 1 BUD22 MetRS-N PF09635.5 KFO97702.1 - 2.9 8.3 9.1 2.3 8.6 2.2 3.2 3 1 0 3 3 3 0 MetRS-N binding domain TcdB_N PF12918.2 KFO97702.1 - 2.9 8.0 13.2 6.9 6.8 0.8 4.1 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Lysyl_oxidase PF01186.12 KFO97703.1 - 2.5e-120 399.6 9.2 2.7e-120 399.4 6.4 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.6 KFO97703.1 - 0.003 17.5 0.0 0.023 14.7 0.0 2.2 2 0 0 2 2 2 1 CARDB zf-C2HC_2 PF13913.1 KFO97704.1 - 1.4e-18 66.0 10.1 4.4e-11 42.1 0.6 2.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KFO97704.1 - 0.0004 20.5 5.3 0.013 15.8 0.1 2.7 3 0 0 3 3 2 2 Zinc finger, C2H2 type Sgf11 PF08209.6 KFO97704.1 - 0.0067 15.7 0.4 0.25 10.6 0.0 2.4 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) c-SKI_SMAD_bind PF08782.5 KFO97704.1 - 0.015 15.3 0.5 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 c-SKI Smad4 binding domain zinc_ribbon_4 PF13717.1 KFO97704.1 - 0.035 13.7 1.4 3.4 7.4 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFO97704.1 - 0.049 13.2 1.2 4.5 6.9 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFO97704.1 - 0.11 11.7 1.3 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rad50_zn_hook PF04423.9 KFO97704.1 - 0.15 11.5 0.1 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.3 KFO97704.1 - 0.16 12.1 0.4 9.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCHC PF00098.18 KFO97704.1 - 0.28 11.1 3.9 4.5 7.3 0.3 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2_2 PF13465.1 KFO97704.1 - 0.29 11.5 2.5 3.7 8.0 0.2 2.8 2 1 0 2 2 2 0 Zinc-finger double domain Prok-RING_1 PF14446.1 KFO97704.1 - 0.37 10.5 2.0 5.9 6.7 0.0 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_6 PF13912.1 KFO97704.1 - 0.58 10.1 5.7 11 6.1 0.6 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger DZR PF12773.2 KFO97704.1 - 0.59 10.0 3.8 3.8 7.3 2.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 KFO97705.1 - 4.9e-06 26.5 14.3 0.45 10.9 3.4 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO97705.1 - 2.1e-05 24.5 0.0 2.1e-05 24.5 0.0 3.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO97705.1 - 7.5e-05 22.7 13.4 1.2 9.6 0.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger RVT_1 PF00078.22 KFO97706.1 - 2e-21 76.3 0.0 2.9e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFO97706.1 - 6.8e-08 31.9 0.2 1.3e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain HATPase_c PF02518.21 KFO97707.1 - 2.5e-14 52.9 0.0 1.4e-13 50.4 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 KFO97707.1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Fasciclin PF02469.17 KFO97708.1 - 3e-105 347.3 0.1 3.2e-27 95.0 0.0 4.4 4 0 0 4 4 4 4 Fasciclin domain Lig_chan PF00060.21 KFO97709.1 - 2.8e-44 150.3 0.3 4.6e-44 149.7 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFO97709.1 - 2.3e-27 95.6 0.0 3.8e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFO97709.1 - 2.2e-23 81.9 0.1 5.1e-23 80.8 0.1 1.7 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 KFO97709.1 - 3.6e-14 52.3 0.0 6.5e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Receptor family ligand binding region DUF1469 PF07332.6 KFO97709.1 - 0.0079 15.9 0.2 0.0079 15.9 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1469) NADH-u_ox-rdase PF10785.4 KFO97709.1 - 0.02 15.0 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit LRR_6 PF13516.1 KFO97710.1 - 6.7e-17 59.6 15.9 0.00076 19.2 0.1 10.1 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.2 KFO97710.1 - 1.5e-06 27.7 23.0 0.0049 16.4 2.4 5.7 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO97710.1 - 3.2e-05 23.3 18.4 6.2 7.2 0.2 8.0 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.1 KFO97710.1 - 0.00011 21.8 16.8 0.023 14.4 0.2 5.7 5 2 0 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 KFO97710.1 - 0.062 13.5 21.7 2 8.9 0.1 7.6 8 0 0 8 8 8 0 Leucine rich repeat DUF4632 PF15451.1 KFO97710.1 - 0.08 12.8 1.0 0.18 11.7 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) RHD PF00554.17 KFO97711.1 - 7.9e-20 71.2 0.1 8.4e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Rel homology domain (RHD) CLPTM1 PF05602.7 KFO97712.1 - 4e-116 388.3 0.4 4.9e-116 388.0 0.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Thiolase_N PF00108.18 KFO97713.1 - 2.7e-89 298.6 0.1 3.6e-89 298.2 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFO97713.1 - 1.5e-49 166.5 0.0 2.8e-49 165.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFO97713.1 - 5.4e-08 32.6 0.7 3.7e-07 29.8 0.3 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KFO97713.1 - 0.076 12.6 1.7 2.6 7.7 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ECH PF00378.15 KFO97714.1 - 2.4e-73 246.2 0.1 3.9e-73 245.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH_N PF02737.13 KFO97714.1 - 8.1e-57 191.7 1.1 1.6e-56 190.8 0.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFO97714.1 - 1.6e-25 89.2 1.4 2.6e-25 88.6 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ras PF00071.17 KFO97716.1 - 4.5e-10 39.1 0.1 4.9e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 Ras family AAA_24 PF13479.1 KFO97716.1 - 0.01 15.4 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFO97716.1 - 0.022 14.7 0.0 0.022 14.7 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KFO97716.1 - 0.037 14.1 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFO97716.1 - 0.044 13.3 0.2 0.05 13.1 0.2 1.3 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KFO97716.1 - 0.053 13.2 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 KFO97716.1 - 0.056 12.6 0.1 0.058 12.6 0.1 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.16 KFO97716.1 - 0.062 12.5 0.0 0.062 12.5 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family Miro PF08477.8 KFO97716.1 - 0.062 13.7 0.0 0.066 13.7 0.0 1.1 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 KFO97716.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pox_A32 PF04665.7 KFO97716.1 - 0.13 11.5 0.1 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Gtr1_RagA PF04670.7 KFO97716.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Kinesin PF00225.18 KFO97717.1 - 1.8e-117 391.7 0.0 1.8e-117 391.7 0.0 1.9 3 0 0 3 3 3 1 Kinesin motor domain PIF1 PF05970.9 KFO97717.1 - 0.0002 20.4 1.4 0.052 12.4 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase FlxA PF14282.1 KFO97717.1 - 0.15 12.0 0.1 0.15 12.0 0.1 4.2 2 2 2 4 4 4 0 FlxA-like protein AAA_22 PF13401.1 KFO97717.1 - 0.36 10.9 0.0 0.36 10.9 0.0 2.7 2 1 0 3 3 3 0 AAA domain DUF2321 PF10083.4 KFO97717.1 - 6.4 6.2 7.9 0.46 9.9 1.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) MACPF PF01823.14 KFO97718.1 - 2.6e-08 33.8 0.0 4.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 MAC/Perforin domain Adeno_E3_CR2 PF02439.10 KFO97718.1 - 0.3 10.6 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 zf-RING_2 PF13639.1 KFO97719.1 - 1.3e-09 37.6 1.5 3.2e-09 36.4 1.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFO97719.1 - 4.2e-08 33.1 0.9 7.9e-08 32.2 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFO97719.1 - 4.2e-08 32.7 1.4 9.1e-08 31.6 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO97719.1 - 7.9e-06 25.5 1.6 1.8e-05 24.3 1.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFO97719.1 - 6.1e-05 22.7 0.5 0.00012 21.7 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KFO97719.1 - 0.00014 21.7 5.2 0.0021 18.0 0.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFO97719.1 - 0.00061 19.4 1.1 0.0028 17.3 0.7 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFO97719.1 - 0.0015 18.1 2.9 0.0035 16.9 1.4 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFO97719.1 - 0.0016 18.2 3.4 0.0067 16.2 0.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Trm112p PF03966.11 KFO97719.1 - 0.033 14.5 0.2 0.068 13.5 0.1 1.5 1 0 0 1 1 1 0 Trm112p-like protein zf-RING_4 PF14570.1 KFO97719.1 - 0.038 13.5 1.3 0.058 12.9 0.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFO97719.1 - 0.049 13.5 1.4 0.16 11.9 1.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-UDP PF14569.1 KFO97719.1 - 0.055 13.2 0.1 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger PHD PF00628.24 KFO97719.1 - 0.074 12.7 3.5 0.26 11.0 2.4 2.0 1 1 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 KFO97719.1 - 0.1 12.1 1.2 0.2 11.1 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_5 PF13719.1 KFO97719.1 - 0.11 12.0 0.7 3 7.5 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 KFO97719.1 - 0.39 10.4 3.3 7 6.4 0.0 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 CNTF PF01110.12 KFO97720.1 - 4.3e-83 277.4 0.2 5e-83 277.2 0.1 1.0 1 0 0 1 1 1 1 Ciliary neurotrophic factor DUF2157 PF09925.4 KFO97720.1 - 0.082 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Thioredoxin PF00085.15 KFO97721.1 - 5.7e-11 42.0 0.0 1.1e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFO97721.1 - 0.078 13.1 0.1 0.31 11.1 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like Med19 PF10278.4 KFO97722.1 - 9.3e-80 266.4 13.0 1.1e-79 266.3 9.0 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.7 KFO97722.1 - 0.002 18.0 2.8 0.002 18.0 2.0 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Zip PF02535.17 KFO97722.1 - 0.025 13.6 2.5 0.026 13.5 1.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.6 KFO97722.1 - 0.83 9.2 25.0 1.2 8.7 17.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Herpes_DNAp_acc PF04929.7 KFO97722.1 - 0.98 8.3 10.4 1.1 8.1 7.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Nucleo_P87 PF07267.6 KFO97722.1 - 3.8 6.0 5.9 4.7 5.7 4.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1510 PF07423.6 KFO97722.1 - 5.1 6.4 12.0 6.5 6.0 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YqfQ PF14181.1 KFO97722.1 - 7.7 6.5 13.6 11 5.9 9.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein zf-DHHC PF01529.15 KFO97723.1 - 1.8e-41 141.4 0.9 3.1e-41 140.6 0.6 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Clp1 PF06807.9 KFO97724.1 - 1.1e-58 198.2 0.0 1.5e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KFO97724.1 - 9e-22 77.2 0.0 2.1e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KFO97724.1 - 0.0044 16.9 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KFO97724.1 - 0.0095 15.4 0.2 0.019 14.5 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KFO97724.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 KFO97724.1 - 0.012 16.3 0.1 0.039 14.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFO97724.1 - 0.028 14.2 0.0 0.083 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFO97724.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFO97724.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Yippee-Mis18 PF03226.9 KFO97725.1 - 5e-19 68.1 0.6 6.1e-19 67.8 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPgrasp_YheCD PF14398.1 KFO97725.1 - 0.033 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp AlcCBM31 PF11606.3 KFO97725.1 - 0.039 13.9 0.2 1.1 9.2 0.0 2.1 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein DZR PF12773.2 KFO97725.1 - 0.15 11.9 1.8 1.9 8.3 1.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon GFA PF04828.9 KFO97725.1 - 0.27 11.2 2.4 2.3 8.2 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-CHY PF05495.7 KFO97725.1 - 0.33 11.1 3.7 1.3 9.2 2.5 1.9 1 1 1 2 2 2 0 CHY zinc finger zf-Tim10_DDP PF02953.10 KFO97726.1 - 8.5e-20 69.8 0.8 1.3e-19 69.2 0.5 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger P2X_receptor PF00864.14 KFO97727.1 - 9e-56 189.1 0.0 9.9e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 ATP P2X receptor SSrecog PF03531.9 KFO97728.1 - 4e-102 340.2 0.0 6e-102 339.6 0.0 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KFO97728.1 - 4.4e-29 100.3 0.1 1.7e-27 95.2 0.1 2.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HMG_box PF00505.14 KFO97728.1 - 4.1e-24 84.6 4.0 4.1e-24 84.6 2.8 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO97728.1 - 2.2e-13 50.3 3.6 2.2e-13 50.3 2.5 2.4 2 0 0 2 2 2 1 HMG-box domain KTSC PF13619.1 KFO97728.1 - 0.0088 15.6 0.2 3.4 7.3 0.0 2.6 2 0 0 2 2 2 2 KTSC domain 7tm_1 PF00001.16 KFO97729.1 - 5.8e-39 133.7 9.7 5.4e-25 88.0 2.8 2.0 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFO97729.1 - 0.24 10.4 3.0 0.35 9.9 0.3 1.9 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv INCENP_ARK-bind PF03941.10 KFO97730.1 - 3.2e-20 71.7 0.1 7.4e-20 70.5 0.1 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region YwhD PF08741.5 KFO97730.1 - 3.6 6.9 8.4 3.8 6.8 3.4 2.2 2 0 0 2 2 2 0 YwhD family INCENP_ARK-bind PF03941.10 KFO97731.1 - 3.4e-20 71.6 0.0 1.1e-19 69.9 0.0 2.0 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Uteroglobin PF01099.12 KFO97732.1 - 3.6e-05 23.4 0.0 4.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Uteroglobin family EFG_IV PF03764.13 KFO97732.1 - 0.089 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor G, domain IV SHIPPO-rpt PF07004.7 KFO97733.1 - 1.7e-05 25.4 29.8 0.082 13.8 2.6 5.6 5 2 0 5 5 5 4 Sperm-tail PG-rich repeat SNARE PF05739.14 KFO97734.1 - 1.2e-09 37.6 0.0 1.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Ric8 PF10165.4 KFO97735.1 - 1.3e-162 541.7 0.6 1.3e-162 541.7 0.4 1.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Occludin_ELL PF07303.8 KFO97735.1 - 0.012 16.3 2.3 0.24 12.1 0.1 3.1 3 0 0 3 3 3 0 Occludin homology domain SIR2 PF02146.12 KFO97736.1 - 5.6e-54 182.5 0.0 7.2e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Rad50_zn_hook PF04423.9 KFO97736.1 - 0.4 10.1 4.3 4.1 6.9 0.1 2.4 1 1 1 2 2 2 0 Rad50 zinc hook motif Glyco_hydro_65m PF03632.10 KFO97737.1 - 2e-85 286.6 0.0 5.6e-84 281.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Dispanin PF04505.7 KFO97738.1 - 9.8e-22 76.2 0.1 1.3e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein PA14 PF07691.7 KFO97739.1 - 6.4e-18 64.7 0.0 1.3e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain CHGN PF05679.11 KFO97739.1 - 7.8e-17 61.1 0.0 2.1e-16 59.7 0.0 1.7 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 KFO97739.1 - 2.4e-07 30.1 1.6 4.6e-07 29.2 1.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFO97739.1 - 0.0024 17.0 1.5 0.6 9.1 0.7 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Thioredoxin_8 PF13905.1 KFO97739.1 - 0.012 15.7 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Arm PF00514.18 KFO97740.1 - 1.5e-21 75.3 0.4 1.3e-06 27.9 0.0 5.7 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFO97740.1 - 0.00016 21.8 0.1 0.0021 18.3 0.0 2.8 2 1 0 2 2 2 1 HEAT repeats DUF383 PF04063.9 KFO97740.1 - 0.01 15.4 0.1 7.2 6.0 0.1 3.4 1 1 1 2 2 2 2 Domain of unknown function (DUF383) HEAT PF02985.17 KFO97740.1 - 0.015 15.3 0.0 0.23 11.6 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat Proteasom_PSMB PF10508.4 KFO97740.1 - 0.015 13.5 0.1 0.039 12.2 0.1 1.6 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 KFO97740.1 - 0.051 11.8 0.1 0.14 10.4 0.0 1.7 2 0 0 2 2 2 0 Adaptin N terminal region TIR PF01582.15 KFO97741.1 - 1.6e-17 63.2 0.0 2.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.1 KFO97741.1 - 5.9e-09 35.9 0.0 1.6e-08 34.6 0.0 1.8 1 1 1 2 2 2 1 TIR domain Ig_2 PF13895.1 KFO97741.1 - 0.00027 21.0 0.3 0.00062 19.8 0.2 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO97741.1 - 0.031 14.7 0.5 2.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain BiPBP_C PF06832.7 KFO97741.1 - 0.036 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family I-set PF07679.11 KFO97741.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain Anoctamin PF04547.7 KFO97742.1 - 1e-121 406.7 17.2 1.3e-121 406.4 11.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PhnH PF05845.7 KFO97742.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) PSS PF03034.10 KFO97743.1 - 1.3e-114 382.3 15.3 2e-114 381.7 10.6 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF3104 PF11302.3 KFO97743.1 - 2.3 7.6 4.4 3.3 7.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) C2 PF00168.25 KFO97744.1 - 4.9e-22 77.5 0.0 7.6e-16 57.7 0.1 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 KFO97744.1 - 0.096 12.1 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 CEP76 C2 domain DOCK-C2 PF14429.1 KFO97744.1 - 0.13 11.9 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins AAA_12 PF13087.1 KFO97745.1 - 2.7e-51 173.8 0.0 4e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFO97745.1 - 7e-45 153.4 4.8 2.3e-44 151.7 0.1 3.7 3 2 1 4 4 4 1 AAA domain AAA_19 PF13245.1 KFO97745.1 - 1.7e-15 56.5 0.7 6.7e-14 51.4 0.2 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFO97745.1 - 7.9e-12 45.1 0.0 5.8e-10 39.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain R3H PF01424.17 KFO97745.1 - 4.3e-11 42.3 0.3 1.2e-10 40.8 0.2 1.8 1 0 0 1 1 1 1 R3H domain zf-AN1 PF01428.11 KFO97745.1 - 3.2e-09 36.5 7.1 8.7e-09 35.1 4.9 1.8 1 0 0 1 1 1 1 AN1-like Zinc finger Helicase_RecD PF05127.9 KFO97745.1 - 1e-08 35.0 0.0 0.005 16.5 0.0 3.7 4 0 0 4 4 3 2 Helicase Viral_helicase1 PF01443.13 KFO97745.1 - 2e-07 30.7 0.7 0.19 11.1 0.1 3.5 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KFO97745.1 - 0.00032 20.2 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFO97745.1 - 0.00075 19.6 0.1 0.004 17.3 0.0 2.2 3 0 0 3 3 1 1 AAA domain IstB_IS21 PF01695.12 KFO97745.1 - 0.00093 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFO97745.1 - 0.0011 18.3 0.0 0.005 16.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KFO97745.1 - 0.0012 18.5 0.1 0.0032 17.2 0.1 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain FtsK_SpoIIIE PF01580.13 KFO97745.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family MobB PF03205.9 KFO97745.1 - 0.0014 18.3 0.0 0.027 14.1 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 KFO97745.1 - 0.0018 18.1 0.0 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KFO97745.1 - 0.0043 16.3 0.0 0.0084 15.4 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 KFO97745.1 - 0.0058 15.6 0.1 0.06 12.3 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Zot PF05707.7 KFO97745.1 - 0.0059 16.0 0.0 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 KFO97745.1 - 0.0062 16.5 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 KFO97745.1 - 0.0075 15.2 0.0 0.042 12.7 0.0 1.9 2 0 0 2 2 2 1 PIF1-like helicase AAA PF00004.24 KFO97745.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KFO97745.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DnaB_C PF03796.10 KFO97745.1 - 0.035 13.0 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PhoH PF02562.11 KFO97745.1 - 0.043 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 KFO97745.1 - 0.063 12.2 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.1 KFO97745.1 - 0.088 13.6 0.0 0.33 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFO97745.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Herpes_ori_bp PF02399.10 KFO97745.1 - 0.19 9.6 0.0 0.3 9.0 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Ribosomal_L21p PF00829.16 KFO97746.1 - 1.1e-20 73.5 0.0 2.3e-20 72.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein Ras PF00071.17 KFO97747.1 - 1.8e-25 89.1 0.0 2.1e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97747.1 - 6.6e-10 39.5 0.0 9.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Glyco_hydro_31 PF01055.21 KFO97748.1 - 5.3e-30 104.6 0.0 8.2e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DnaJ PF00226.26 KFO97749.1 - 3.6e-14 52.2 0.4 9e-14 50.9 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_5 PF13893.1 KFO97749.1 - 1.5e-08 34.3 0.0 4.7e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO97749.1 - 1.2e-05 24.8 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO97749.1 - 2.8e-05 24.0 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SpoVR PF04293.8 KFO97749.1 - 0.83 7.9 8.2 1.3 7.3 5.7 1.2 1 0 0 1 1 1 0 SpoVR like protein FAD-SLDH PF12318.3 KFO97749.1 - 1.1 8.9 6.0 0.35 10.5 1.8 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase BORG_CEP PF14957.1 KFO97750.1 - 2e-07 31.9 0.2 4.2e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 Cdc42 effector GFRP PF06399.8 KFO97751.1 - 5e-38 128.5 0.1 5.5e-38 128.4 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) TPR_11 PF13414.1 KFO97752.1 - 1.9e-05 24.1 1.4 0.11 12.2 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 KFO97752.1 - 3.2e-05 24.4 0.6 0.51 11.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFO97752.1 - 0.00038 20.4 0.1 0.013 15.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97752.1 - 0.004 17.4 0.2 5.5 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFO97752.1 - 0.1 12.4 1.8 0.65 9.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Spc24 PF08286.6 KFO97752.1 - 0.33 10.6 2.5 0.68 9.6 0.4 2.5 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF883 PF05957.8 KFO97752.1 - 2.6 8.5 5.3 1.5 9.2 0.2 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Rad51 PF08423.6 KFO97753.1 - 6.9e-142 470.8 0.1 8.6e-142 470.5 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFO97753.1 - 1.7e-14 53.7 0.0 2.4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KFO97753.1 - 5.3e-13 48.9 0.7 1.5e-12 47.4 0.5 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 KFO97753.1 - 2.1e-08 33.5 0.1 3.2e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KFO97753.1 - 2.7e-05 23.4 1.3 9.1e-05 21.6 0.4 2.2 2 1 0 2 2 2 1 KaiC AAA_22 PF13401.1 KFO97753.1 - 0.00064 19.8 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain HHH PF00633.18 KFO97753.1 - 0.0015 18.1 0.2 0.0037 16.8 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 KFO97753.1 - 0.038 14.2 0.0 0.25 11.6 0.0 2.0 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein PseudoU_synth_2 PF00849.17 KFO97756.1 - 5e-30 104.4 0.0 7.6e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase PCMT PF01135.14 KFO97757.1 - 9.8e-81 270.2 0.0 1.1e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KFO97757.1 - 1.8e-08 34.9 0.0 2.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO97757.1 - 4.8e-08 32.7 0.0 7.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO97757.1 - 4.6e-05 23.8 0.0 0.00012 22.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFO97757.1 - 0.0002 20.5 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.5 KFO97757.1 - 0.00032 20.2 0.0 0.00038 20.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.1 KFO97757.1 - 0.0019 18.5 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFO97757.1 - 0.0021 18.0 0.0 0.0049 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO97757.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFO97757.1 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KFO97757.1 - 0.063 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KFO97757.1 - 0.077 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 KFO97757.1 - 0.13 11.2 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase CCDC32 PF14989.1 KFO97758.1 - 8.7e-53 178.1 0.1 1e-52 177.8 0.1 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing 32 BAH PF01426.13 KFO97759.1 - 1.2e-14 54.0 0.1 3.5e-14 52.5 0.0 1.7 1 1 0 1 1 1 1 BAH domain DUF4437 PF14499.1 KFO97759.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Acyl-CoA_dh_1 PF00441.19 KFO97760.1 - 8.6e-39 133.0 0.1 1.3e-38 132.4 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFO97760.1 - 1.9e-33 115.3 0.0 3.4e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFO97760.1 - 1.9e-17 62.5 0.0 3.4e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFO97760.1 - 9.2e-10 38.8 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TPR_MLP1_2 PF07926.7 KFO97761.1 - 0.0026 17.5 3.8 0.0026 17.5 2.6 2.7 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein EIAV_Rev PF11129.3 KFO97761.1 - 0.19 11.7 7.2 0.67 9.9 0.2 2.1 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus Mit_ribos_Mrp51 PF11709.3 KFO97761.1 - 0.23 10.6 3.1 0.19 10.8 1.5 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit HALZ PF02183.13 KFO97761.1 - 0.34 10.6 15.3 0.17 11.6 0.4 3.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper zf-ZPR1 PF03367.8 KFO97761.1 - 0.37 9.9 6.0 0.72 8.9 0.2 2.5 2 0 0 2 2 2 0 ZPR1 zinc-finger domain CP12 PF02672.10 KFO97761.1 - 0.44 11.0 11.0 0.088 13.2 2.0 2.6 2 0 0 2 2 2 0 CP12 domain Macoilin PF09726.4 KFO97761.1 - 0.88 7.7 17.6 0.23 9.7 2.8 2.0 2 0 0 2 2 2 0 Transmembrane protein Transglut_i_TM PF14400.1 KFO97761.1 - 1 8.8 5.3 0.14 11.6 0.4 1.9 2 1 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices APG6 PF04111.7 KFO97761.1 - 1.3 7.9 26.2 2.3 7.2 9.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 KFO97761.1 - 1.5 7.4 19.4 2.1 6.8 13.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Vps51 PF08700.6 KFO97761.1 - 1.5 8.7 6.3 1.9 8.4 0.2 2.5 2 0 0 2 2 2 0 Vps51/Vps67 DivIC PF04977.10 KFO97761.1 - 1.8 8.0 17.0 0.072 12.5 1.9 3.3 2 2 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.1 KFO97761.1 - 2.8 6.8 11.1 4.2 6.2 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 KFO97761.1 - 3.8 7.1 21.2 7.5 6.1 5.9 2.2 1 1 1 2 2 2 0 Mnd1 family Seryl_tRNA_N PF02403.17 KFO97761.1 - 6.5 6.8 20.3 10 6.1 3.4 3.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 KFO97761.1 - 9.3 6.2 26.9 5.5 6.9 4.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Patched PF02460.13 KFO97762.1 - 0.18 9.7 34.7 0.32 8.8 9.5 2.4 2 1 0 2 2 2 0 Patched family Sterol-sensing PF12349.3 KFO97762.1 - 4.9 6.6 30.4 0.021 14.3 10.3 2.7 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation DUF4594 PF15266.1 KFO97763.1 - 1.8e-24 86.8 11.1 1.8e-24 86.8 7.7 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4594) MHC_I_C PF06623.6 KFO97763.1 - 0.099 12.1 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 MHC_I C-terminus IncA PF04156.9 KFO97763.1 - 0.22 11.0 0.6 0.3 10.6 0.4 1.3 1 0 0 1 1 1 0 IncA protein PI-PLC-X PF00388.14 KFO97764.1 - 3.6e-67 224.3 0.1 9.7e-67 222.9 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFO97764.1 - 3.6e-44 149.5 2.1 8.3e-44 148.3 1.5 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFO97764.1 - 2.5e-22 78.6 0.0 7.1e-22 77.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFO97764.1 - 8e-07 28.8 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 KFO97765.1 - 1.4e-66 224.2 0.0 1.9e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97765.1 - 8.7e-44 149.5 0.0 1.2e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFO97765.1 - 1.4e-13 51.0 1.1 3.2e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KFO97765.1 - 3.5e-06 26.2 0.0 5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFO97765.1 - 0.063 12.9 0.3 7 6.2 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Mad3_BUB1_I PF08311.7 KFO97766.1 - 1e-45 154.5 0.1 1e-45 154.5 0.1 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 MerR-DNA-bind PF09278.6 KFO97766.1 - 0.00099 19.4 5.9 0.0036 17.6 4.1 2.0 1 0 0 1 1 1 1 MerR, DNA binding Pkinase PF00069.20 KFO97766.1 - 0.0061 15.7 0.0 0.0061 15.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain EAP30 PF04157.11 KFO97766.1 - 0.022 13.9 2.5 0.057 12.5 1.7 1.7 1 0 0 1 1 1 0 EAP30/Vps36 family Orthopox_A5L PF06193.6 KFO97766.1 - 1.6 8.6 11.4 2.7 7.8 6.0 2.5 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like K_oxygenase PF13434.1 KFO97766.1 - 4.1 6.2 7.3 6.9 5.4 5.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) V_ATPase_I PF01496.14 KFO97766.1 - 8.3 4.1 7.9 13 3.5 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cadherin PF00028.12 KFO97767.1 - 5.3e-16 58.6 0.5 1e-06 28.8 0.0 2.4 2 0 0 2 2 2 2 Cadherin domain Hormone_2 PF00123.15 KFO97768.1 - 1.6e-17 62.9 0.0 2.7e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 Peptide hormone HSBP1 PF06825.7 KFO97768.1 - 0.062 12.8 0.3 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 SAND PF01342.16 KFO97769.1 - 3.8e-26 90.6 0.1 1.1e-25 89.1 0.0 1.8 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.13 KFO97769.1 - 1.7e-10 40.5 16.5 1.7e-10 40.5 11.4 1.9 2 0 0 2 2 2 1 MYND finger Transmemb_17 PF09799.4 KFO97770.1 - 7.1e-28 97.1 8.8 8.8e-28 96.8 6.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein PTB PF08416.8 KFO97771.1 - 8.7e-47 158.3 3.0 1.6e-46 157.4 2.1 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH3_1 PF00018.23 KFO97771.1 - 1.6e-10 40.1 0.1 4.5e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFO97771.1 - 6.7e-09 35.2 0.0 1.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO97771.1 - 9.3e-06 25.0 0.0 1.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.18 KFO97771.1 - 9.3e-06 25.6 1.9 2.1e-05 24.5 0.2 2.2 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_3 PF08239.6 KFO97771.1 - 0.037 14.2 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Transaldolase PF00923.14 KFO97772.1 - 2.1e-98 329.0 0.0 2.3e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase DJ-1_PfpI PF01965.19 KFO97773.1 - 1e-08 34.7 0.0 1.9e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family Alpha_GJ PF03229.8 KFO97774.1 - 0.4 11.0 5.0 0.28 11.5 2.5 1.5 1 1 1 2 2 2 0 Alphavirus glycoprotein J ATP1G1_PLM_MAT8 PF02038.11 KFO97774.1 - 0.72 8.9 3.3 1.1 8.3 2.3 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Neisseria_TspB PF05616.8 KFO97774.1 - 0.78 8.0 9.7 0.97 7.7 6.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein NACHT PF05729.7 KFO97775.1 - 2.5e-34 118.3 0.0 5.7e-34 117.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFO97775.1 - 7e-06 26.1 0.0 0.00011 22.3 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFO97775.1 - 0.00021 21.4 0.0 0.001 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFO97775.1 - 0.00096 18.8 0.0 0.04 13.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KFO97775.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 KFO97775.1 - 0.022 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KFO97775.1 - 0.13 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TPR_11 PF13414.1 KFO97776.1 - 9.7e-10 37.9 3.8 8.6e-05 22.1 1.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFO97776.1 - 9.3e-08 31.4 1.3 0.00031 20.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat FKBP_C PF00254.23 KFO97776.1 - 0.0015 18.4 0.0 0.006 16.5 0.0 2.0 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_16 PF13432.1 KFO97776.1 - 0.006 17.2 0.5 3.1 8.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat PaREP1 PF05942.6 KFO97776.1 - 0.051 13.4 0.2 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family TPR_1 PF00515.23 KFO97776.1 - 0.33 10.6 10.0 0.63 9.7 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFO97776.1 - 4.1 7.6 9.9 4.9 7.3 2.1 2.9 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 EF-hand_1 PF00036.27 KFO97777.1 - 1.4e-32 108.5 13.6 4.1e-10 38.2 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFO97777.1 - 2.8e-26 91.4 6.7 3.7e-17 62.2 1.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFO97777.1 - 5.1e-26 88.1 5.7 2.8e-09 36.0 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFO97777.1 - 1.1e-24 85.8 11.8 2.3e-14 52.7 0.8 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFO97777.1 - 1.9e-23 80.7 9.7 2.4e-09 36.1 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KFO97777.1 - 1.1e-09 38.0 0.1 0.00063 19.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFO97777.1 - 0.00011 22.1 0.1 0.0033 17.4 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFO97777.1 - 0.0016 18.1 4.8 0.0032 17.1 0.2 2.9 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand OST-HTH PF12872.2 KFO97777.1 - 0.047 13.5 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Prefoldin_3 PF13758.1 KFO97777.1 - 0.062 13.0 0.1 0.17 11.6 0.0 1.6 1 1 1 2 2 2 0 Prefoldin subunit Complex1_51K PF01512.12 KFO97779.1 - 2.7e-24 85.6 0.0 3.4e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit Mito_carr PF00153.22 KFO97780.1 - 0.0022 17.6 0.0 0.39 10.4 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein Nup160 PF11715.3 KFO97782.1 - 4.7e-101 338.5 0.0 6.5e-101 338.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 RhoGEF PF00621.15 KFO97783.1 - 5.5e-20 72.0 0.0 7.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain GSHPx PF00255.14 KFO97784.1 - 1.3e-20 72.7 0.4 1.6e-20 72.4 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Ras PF00071.17 KFO97785.1 - 5.8e-10 38.7 0.0 6.6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Ras family NACHT PF05729.7 KFO97785.1 - 0.0029 17.3 0.0 0.0034 17.0 0.0 1.1 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 KFO97785.1 - 0.012 16.0 0.0 0.014 15.8 0.0 1.1 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 KFO97785.1 - 0.017 15.2 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KFO97785.1 - 0.026 13.6 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFO97785.1 - 0.027 14.4 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 KFO97785.1 - 0.035 13.6 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KFO97785.1 - 0.036 13.2 0.0 0.036 13.2 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family Pox_A32 PF04665.7 KFO97785.1 - 0.042 13.1 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.1 KFO97785.1 - 0.084 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KFO97785.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein PduV-EutP PF10662.4 KFO97785.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KFO97785.1 - 0.14 11.3 0.0 0.15 11.2 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 KFO97785.1 - 0.14 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UNC-93 PF05978.11 KFO97786.1 - 5.8e-07 29.1 4.4 2.2e-05 24.0 1.2 2.6 2 0 0 2 2 2 2 Ion channel regulatory protein UNC-93 Aldedh PF00171.17 KFO97787.1 - 1.5e-81 274.1 0.0 1.8e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFO97787.1 - 0.00014 20.7 0.0 0.00018 20.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) T-box PF00907.17 KFO97788.1 - 4.3e-82 274.0 0.0 5e-82 273.8 0.0 1.0 1 0 0 1 1 1 1 T-box ABC_transp_aux PF09822.4 KFO97788.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system 7tm_4 PF13853.1 KFO97789.1 - 1.6e-38 131.7 13.4 2.9e-38 130.9 9.3 1.4 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO97789.1 - 2.1e-28 99.1 16.3 2.5e-28 98.9 11.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFO97791.1 - 3e-43 147.0 11.4 3e-43 147.0 7.9 2.3 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO97791.1 - 1.9e-25 89.4 19.0 2.6e-25 89.0 13.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) XPG_N PF00752.12 KFO97792.1 - 1.2e-36 124.9 0.0 3.3e-36 123.5 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KFO97792.1 - 9e-31 105.8 0.0 2.7e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 KFO97792.1 - 2.4e-07 30.8 0.0 1.1e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold UPF0197 PF05251.7 KFO97793.1 - 3.7e-40 136.0 6.3 4.1e-40 135.9 4.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) TctB PF07331.6 KFO97793.1 - 0.0039 16.8 1.4 0.0043 16.7 1.0 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF4234 PF14018.1 KFO97793.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Cyt_c_ox_IV PF12270.3 KFO97793.1 - 0.34 10.6 5.7 0.43 10.3 3.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV UPF0233 PF06781.7 KFO97793.1 - 0.75 9.4 4.4 1.5 8.5 3.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF4131 PF13567.1 KFO97793.1 - 1.3 8.3 5.7 1.6 8.1 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MRF_C2 PF13888.1 KFO97794.1 - 2e-43 147.5 1.0 3.7e-43 146.7 0.7 1.5 1 0 0 1 1 1 1 Myelin gene regulatory factor C-terminal domain 2 NDT80_PhoG PF05224.7 KFO97794.1 - 6.7e-28 97.9 0.5 5.3e-27 95.0 0.4 2.2 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family MRF_C1 PF13887.1 KFO97794.1 - 9.8e-24 82.0 1.7 1.6e-23 81.3 1.2 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Peptidase_S74 PF13884.1 KFO97794.1 - 2.8e-15 56.1 0.1 5.2e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase Lipase_3 PF01764.20 KFO97795.1 - 1.1e-10 41.2 0.0 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2348 PF09807.4 KFO97796.1 - 2.7e-99 331.3 1.3 3e-99 331.1 0.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Fork_head PF00250.13 KFO97797.1 - 2.5e-07 30.6 0.5 5e-07 29.6 0.3 1.5 1 0 0 1 1 1 1 Fork head domain NdhM PF10664.4 KFO97797.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M COG6 PF06419.6 KFO97798.1 - 3.9e-198 659.5 11.6 4.4e-198 659.3 8.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Cast PF10174.4 KFO97798.1 - 0.0014 16.7 4.2 0.0022 16.1 2.9 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 KFO97798.1 - 0.0052 16.3 4.7 0.0052 16.3 3.3 2.0 2 0 0 2 2 2 1 IncA protein BLOC1_2 PF10046.4 KFO97798.1 - 0.0091 16.1 3.3 0.035 14.2 2.3 2.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 KFO97798.1 - 0.018 15.3 1.9 0.079 13.3 1.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Nup54 PF13874.1 KFO97798.1 - 0.17 11.5 6.3 0.036 13.7 1.0 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 ERM PF00769.14 KFO97798.1 - 1.6 8.1 12.2 0.076 12.5 3.6 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Prefoldin_2 PF01920.15 KFO97798.1 - 2.2 8.1 9.9 0.97 9.2 0.8 3.0 2 1 1 3 3 3 0 Prefoldin subunit Yae1_N PF09811.4 KFO97799.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal L_HGMIC_fpl PF10242.4 KFO97800.1 - 3.9e-30 105.1 3.3 4.4e-30 105.0 2.3 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 KFO97800.1 - 0.0018 17.9 2.7 0.0018 17.9 1.8 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction UPF0016 PF01169.14 KFO97800.1 - 0.0035 17.4 1.2 0.0086 16.1 0.9 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 Calc_CGRP_IAPP PF00214.14 KFO97801.1 - 5e-24 84.8 0.1 5.7e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family OATP PF03137.15 KFO97802.1 - 4.9e-164 546.3 13.7 5.5e-164 546.1 9.5 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFO97802.1 - 3.8e-22 78.4 26.4 3.5e-20 72.0 6.8 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Kazal_2 PF07648.10 KFO97802.1 - 3.3e-10 39.7 4.6 6.7e-10 38.7 3.2 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFO97802.1 - 0.00092 19.1 3.3 0.0024 17.8 2.3 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain OATP PF03137.15 KFO97803.1 - 1.2e-176 587.9 14.8 1.3e-176 587.8 10.2 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFO97803.1 - 1.3e-21 76.7 20.8 3.1e-19 68.8 11.0 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.10 KFO97803.1 - 7.6e-10 38.5 5.7 1.9e-09 37.3 4.0 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFO97803.1 - 0.0005 20.0 6.0 0.0016 18.4 4.2 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain OATP PF03137.15 KFO97804.1 - 2.8e-176 586.7 10.9 3.3e-176 586.5 7.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFO97804.1 - 8.8e-24 83.8 18.8 1.4e-19 70.0 1.6 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Kazal_2 PF07648.10 KFO97804.1 - 7.1e-11 41.8 5.1 1.7e-10 40.6 3.5 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFO97804.1 - 0.00016 21.6 3.6 0.0004 20.3 2.5 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DUF4446 PF14584.1 KFO97805.1 - 0.02 14.7 0.8 0.02 14.7 0.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Adeno_hexon PF01065.14 KFO97805.1 - 0.19 10.5 1.1 0.25 10.1 0.7 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain APG6 PF04111.7 KFO97805.1 - 2.8 6.8 22.6 4.5 6.2 15.3 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF572 PF04502.8 KFO97805.1 - 3 6.9 17.0 4 6.5 11.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DivIVA PF05103.8 KFO97805.1 - 3.3 7.7 24.1 2.1 8.4 2.0 2.8 2 1 1 3 3 3 0 DivIVA protein DUF1043 PF06295.7 KFO97805.1 - 5 6.7 12.9 1.2 8.8 2.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) Ribonuc_red_lgC PF02867.10 KFO97806.1 - 1.2e-196 654.4 0.0 1.5e-195 650.8 0.0 2.0 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KFO97806.1 - 2.2e-23 81.8 0.1 5.9e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KFO97806.1 - 1.6e-06 28.4 0.2 5.5e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain PEHE PF15275.1 KFO97806.1 - 0.15 12.5 1.3 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 PEHE domain 7tm_1 PF00001.16 KFO97807.1 - 7.1e-27 94.1 22.5 9.6e-27 93.7 15.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFO97807.1 - 1e-24 87.0 10.1 1e-24 87.0 7.0 2.1 2 1 0 2 2 2 1 Olfactory receptor 7TM_GPCR_Srsx PF10320.4 KFO97807.1 - 2e-05 23.9 17.5 0.00016 20.9 12.0 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Globin PF00042.17 KFO97808.1 - 3.3e-29 101.4 0.0 5e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Globin Globin PF00042.17 KFO97809.1 - 1.1e-28 99.8 0.0 2e-28 98.9 0.0 1.4 2 0 0 2 2 2 1 Globin Globin PF00042.17 KFO97810.1 - 8.6e-29 100.1 0.0 1.6e-28 99.2 0.0 1.4 2 0 0 2 2 2 1 Globin 7tm_4 PF13853.1 KFO97811.1 - 5.9e-30 103.9 5.9 5.9e-30 103.9 4.1 2.0 1 1 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO97811.1 - 1.6e-28 99.5 15.6 2e-28 99.2 10.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO97811.1 - 1.9e-09 37.0 9.7 2.1e-09 36.8 6.3 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Folate_rec PF03024.9 KFO97812.1 - 1.8e-56 190.3 24.5 2.2e-56 190.0 17.0 1.1 1 0 0 1 1 1 1 Folate receptor family Ribosomal_S17 PF00366.15 KFO97813.1 - 1.8e-10 40.6 0.1 3.3e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 BAAT_C PF08840.6 KFO97814.1 - 4.5e-65 219.3 0.0 5.5e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bile_Hydr_Trans PF04775.9 KFO97814.1 - 1.8e-33 114.9 0.0 2.6e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region DLH PF01738.13 KFO97814.1 - 1.2e-08 34.5 0.0 4.3e-06 26.1 0.0 3.1 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 KFO97814.1 - 2.5e-06 27.1 0.0 4.6e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFO97814.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFO97814.1 - 0.00019 20.7 0.1 0.0021 17.3 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 KFO97814.1 - 0.0028 16.2 0.0 0.6 8.5 0.0 2.6 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KFO97814.1 - 0.013 15.0 0.0 0.049 13.1 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 KFO97815.1 - 4.3e-73 245.5 0.0 4.8e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 KFO97815.1 - 0.0069 16.1 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFO97815.1 - 0.023 13.9 0.3 0.22 10.7 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.8 KFO97815.1 - 0.048 13.1 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LRR_4 PF12799.2 KFO97816.1 - 7.5e-17 60.5 13.4 3.4e-07 29.7 5.2 3.8 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO97816.1 - 3.8e-09 36.1 9.4 0.00046 19.8 0.0 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 KFO97816.1 - 2.3e-07 30.5 0.7 4.6e-07 29.5 0.4 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 KFO97816.1 - 9.7e-06 24.9 12.1 1.8 8.8 0.5 5.2 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 KFO97816.1 - 0.0017 18.2 9.1 0.98 9.6 0.7 4.8 4 1 2 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 KFO97816.1 - 0.0026 17.6 9.9 9.4 6.9 1.0 5.8 4 2 2 6 6 6 1 Leucine rich repeat ADH_zinc_N PF00107.21 KFO97817.1 - 3.8e-17 62.0 0.0 7.1e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFO97817.1 - 2.8e-12 47.6 0.0 1.5e-11 45.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Orthopox_F14 PF06076.7 KFO97817.1 - 0.0043 17.0 0.1 0.0084 16.1 0.1 1.4 1 0 0 1 1 1 1 Orthopoxvirus F14 protein ClpS PF02617.12 KFO97818.1 - 4.1e-20 71.2 0.1 9.6e-20 70.1 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.15 KFO97818.1 - 5.9e-20 70.7 11.1 5.9e-20 70.7 7.7 2.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 KFO97818.1 - 0.0073 16.1 2.7 0.0073 16.1 1.9 4.7 5 0 0 5 5 5 1 Ring finger domain Ribosomal_L4 PF00573.17 KFO97819.1 - 1.6e-34 118.9 0.1 2.9e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KFO97819.1 - 1.4e-31 108.1 8.0 3.8e-31 106.8 5.6 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain SNAPc19 PF15497.1 KFO97820.1 - 8.2e-13 48.3 16.1 1.6e-06 28.2 5.2 2.0 1 1 1 2 2 2 2 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DNA_pol3_beta_3 PF02768.10 KFO97820.1 - 0.2 11.2 2.9 0.22 11.0 2.0 1.0 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain Spore_III_AB PF09548.5 KFO97820.1 - 0.87 9.3 5.1 0.99 9.1 3.5 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Pkinase PF00069.20 KFO97821.1 - 5.9e-57 192.7 0.0 7.2e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97821.1 - 9.6e-30 103.5 0.0 5.4e-28 97.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO97821.1 - 0.00086 18.3 0.0 0.0021 17.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KFO97821.1 - 0.0033 16.2 0.1 0.0071 15.1 0.0 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KFO97821.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4089 PF13318.1 KFO97821.1 - 0.11 12.8 0.8 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) PIP49_C PF12260.3 KFO97821.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 NAD_binding_6 PF08030.7 KFO97821.1 - 0.14 12.0 0.2 0.42 10.5 0.1 1.8 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Swi3 PF07962.7 KFO97822.1 - 2e-36 123.4 0.4 3.1e-36 122.8 0.3 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RNB PF00773.14 KFO97823.1 - 6.2e-86 288.6 0.1 1.1e-85 287.7 0.1 1.4 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 KFO97823.1 - 0.032 13.7 0.0 0.12 11.8 0.0 2.0 1 0 0 1 1 1 0 Ribonuclease B OB domain EMI PF07546.8 KFO97824.1 - 5.1e-15 55.6 7.3 5.1e-15 55.6 5.0 2.0 2 0 0 2 2 2 1 EMI domain EGF_2 PF07974.8 KFO97824.1 - 0.0029 17.7 11.0 0.0081 16.2 7.6 1.8 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 KFO97825.1 - 3.9e-50 167.5 304.3 0.00036 20.4 11.1 16.8 7 4 9 16 16 16 15 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFO97825.1 - 2.3e-07 30.8 374.6 0.0058 16.7 9.2 25.2 20 10 4 24 24 24 12 EGF-like domain hEGF PF12661.2 KFO97825.1 - 0.00018 21.3 20.8 0.005 16.8 0.3 31.7 36 0 0 36 36 35 12 Human growth factor-like EGF EGF PF00008.22 KFO97825.1 - 0.0032 17.3 11.7 0.0032 17.3 8.1 22.7 21 2 1 22 22 21 9 EGF-like domain Rifin_STEVOR PF02009.11 KFO97825.1 - 0.0044 16.7 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family SIT PF15330.1 KFO97825.1 - 0.021 14.9 0.2 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT BatD PF13584.1 KFO97825.1 - 0.2 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Syndecan PF01034.15 KFO97825.1 - 0.24 11.0 0.0 0.5 10.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 KFO97825.1 - 0.32 10.3 4.4 0.55 9.5 3.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2207 PF09972.4 KFO97825.1 - 0.34 9.4 0.1 0.45 9.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CoatB PF10389.4 KFO97825.1 - 0.86 9.5 2.2 1.5 8.7 1.5 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B Ras PF00071.17 KFO97826.1 - 1.1e-62 210.2 0.1 1.2e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97826.1 - 1.1e-20 74.2 0.0 1.7e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO97826.1 - 2.1e-11 43.4 0.1 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFO97826.1 - 1.5e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFO97826.1 - 8.1e-07 29.2 0.1 2.6e-06 27.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KFO97826.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFO97826.1 - 0.0025 17.0 0.1 0.0056 15.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFO97826.1 - 0.0042 16.1 0.0 0.0047 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFO97826.1 - 0.0053 16.6 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 KFO97826.1 - 0.0055 15.8 0.0 0.0098 15.0 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KFO97826.1 - 0.013 15.4 0.3 0.041 13.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 KFO97826.1 - 0.021 14.1 0.1 0.1 11.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 KFO97826.1 - 0.028 14.7 0.1 0.038 14.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 KFO97826.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFO97826.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DENN PF02141.16 KFO97827.1 - 5.4e-58 195.7 2.5 5.4e-58 195.7 1.7 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 KFO97827.1 - 4.1e-22 78.0 0.6 4.1e-22 78.0 0.4 1.9 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 KFO97827.1 - 3.4e-12 46.1 0.2 1.4e-11 44.1 0.1 2.2 2 0 0 2 2 2 1 uDENN domain PPR_2 PF13041.1 KFO97827.1 - 2.4e-07 30.6 0.0 1.2e-05 25.1 0.0 2.6 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 KFO97827.1 - 0.0062 16.4 0.0 0.04 13.8 0.0 2.5 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.1 KFO97827.1 - 0.014 15.6 0.0 0.056 13.7 0.0 2.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Na_Ca_ex PF01699.19 KFO97828.1 - 2.6e-59 198.8 37.9 1.4e-31 108.9 8.3 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PBP1_TM PF14812.1 KFO97828.1 - 0.019 15.2 0.4 0.069 13.4 0.3 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_ligase_A_M PF01068.16 KFO97828.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Cwf_Cwc_15 PF04889.7 KFO97828.1 - 0.34 10.5 8.4 0.48 10.0 5.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VWA_2 PF13519.1 KFO97829.1 - 2.3e-09 37.5 0.0 4.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain PTPLA PF04387.9 KFO97830.1 - 1.3e-54 184.0 6.9 1.3e-54 184.0 4.8 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA ELO PF01151.13 KFO97830.1 - 0.0043 16.3 8.7 0.007 15.6 6.1 1.4 1 1 0 1 1 1 1 GNS1/SUR4 family DPPIV_N PF00930.16 KFO97831.1 - 3.8e-99 331.6 0.0 5.1e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFO97831.1 - 1.1e-59 201.2 0.0 1.8e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KFO97831.1 - 1.8e-08 34.1 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 KFO97831.1 - 4.9e-08 32.8 0.0 1.6e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFO97831.1 - 0.00019 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFO97831.1 - 0.026 13.9 0.0 0.8 9.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 KFO97831.1 - 0.078 12.3 0.1 0.25 10.7 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 KFO97831.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KFO97831.1 - 0.13 11.5 0.1 0.88 8.8 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family I-set PF07679.11 KFO97832.1 - 1.3e-53 178.8 0.1 1.2e-21 76.3 0.0 4.9 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97832.1 - 3.9e-32 110.2 0.0 4.3e-08 33.1 0.0 4.6 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.16 KFO97832.1 - 6.2e-23 80.7 3.6 2.1e-13 50.2 0.4 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ig_3 PF13927.1 KFO97832.1 - 3.3e-22 78.7 0.3 1.2e-06 28.9 0.1 5.5 5 1 0 5 5 5 4 Immunoglobulin domain ig PF00047.20 KFO97832.1 - 5.5e-18 64.8 0.1 3.5e-06 27.0 0.0 5.0 4 1 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.7 KFO97832.1 - 5.3e-15 55.0 0.4 1.9e-06 27.6 0.1 4.7 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFO97832.1 - 1.5e-12 47.3 2.9 0.00011 22.0 0.0 5.6 5 2 0 5 5 5 2 Immunoglobulin V-set domain C1-set PF07654.10 KFO97832.1 - 1.2e-07 31.5 0.6 0.0036 17.2 0.0 3.9 5 1 0 5 5 5 2 Immunoglobulin C1-set domain Interfer-bind PF09294.5 KFO97832.1 - 0.011 15.6 0.4 0.033 14.2 0.3 1.7 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III PARP PF00644.15 KFO97833.1 - 5.1e-35 120.7 0.1 6.9e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF4480 PF13715.1 KFO97834.1 - 2.8e-12 46.4 0.0 8.9e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4480) Ig_2 PF13895.1 KFO97834.1 - 2.6e-11 43.4 0.0 7.3e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain CarboxypepD_reg PF13620.1 KFO97834.1 - 8.2e-11 41.8 0.2 8.6e-08 32.1 0.0 3.0 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain I-set PF07679.11 KFO97834.1 - 9.1e-08 31.8 0.0 2.7e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFO97834.1 - 2e-06 28.1 0.5 1e-05 25.9 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.14 KFO97834.1 - 6.1e-06 26.2 10.5 6.1e-06 26.2 7.3 2.7 2 0 0 2 2 2 1 Thrombospondin type 1 domain ig PF00047.20 KFO97834.1 - 1e-05 25.5 0.0 2.9e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO97834.1 - 0.068 13.0 2.6 0.089 12.6 0.1 2.5 2 1 0 2 2 2 0 Immunoglobulin V-set domain fn3_3 PF14686.1 KFO97834.1 - 0.078 13.1 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II Formyl_trans_N PF00551.14 KFO97835.1 - 2.4e-26 92.3 0.0 4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KFO97835.1 - 4.5e-11 42.7 0.0 1e-10 41.5 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain OSTbeta PF15048.1 KFO97836.1 - 1.2e-31 109.3 0.1 1.6e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein DUF1191 PF06697.7 KFO97836.1 - 0.15 10.8 0.1 0.22 10.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2474 PF10617.4 KFO97836.1 - 0.28 10.8 3.3 0.51 9.9 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) Ras PF00071.17 KFO97837.1 - 8.2e-33 113.0 0.0 1e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO97837.1 - 5.6e-13 49.4 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO97837.1 - 0.0003 20.0 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF815 PF05673.8 KFO97837.1 - 0.075 11.9 0.0 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Kelch_1 PF01344.20 KFO97838.1 - 7.4e-22 76.6 14.0 4.2e-10 39.0 0.0 6.0 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 KFO97838.1 - 1.4e-18 66.2 7.9 7e-07 29.1 0.0 5.4 5 2 1 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KFO97838.1 - 1.8e-14 52.8 1.6 0.00019 21.0 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 KFO97838.1 - 6.7e-13 48.1 7.4 1.4e-06 27.9 0.0 5.5 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.1 KFO97838.1 - 1.1e-09 38.1 1.1 0.00058 19.9 0.0 4.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO97838.1 - 5.1e-05 23.1 4.3 0.78 9.7 0.0 3.8 3 0 0 3 3 3 2 Kelch motif DUF1668 PF07893.8 KFO97838.1 - 0.0013 17.9 0.4 0.25 10.4 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1668) UBA PF00627.26 KFO97839.1 - 1.3e-05 24.8 1.1 0.12 12.2 0.1 2.2 2 0 0 2 2 2 2 UBA/TS-N domain Sigma54_CBD PF04963.8 KFO97839.1 - 0.00029 20.3 0.2 0.00033 20.1 0.2 1.1 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain UBA_3 PF09288.5 KFO97839.1 - 0.026 14.0 1.0 0.62 9.6 0.4 2.4 2 1 0 2 2 2 0 Fungal ubiquitin-associated domain UBA_2 PF08587.6 KFO97839.1 - 0.065 13.4 0.1 3.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin associated domain (UBA) MutS_III PF05192.13 KFO97841.1 - 0.3 10.8 3.7 0.35 10.6 2.5 1.1 1 0 0 1 1 1 0 MutS domain III DUF885 PF05960.6 KFO97841.1 - 0.77 8.8 7.5 1.1 8.3 5.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) eIF3_N PF09440.5 KFO97841.1 - 2.7 8.1 12.9 0.87 9.7 1.8 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain AAA_2 PF07724.9 KFO97842.1 - 1e-25 90.6 0.0 4e-24 85.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KFO97842.1 - 1.4e-15 56.9 0.0 2.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KFO97842.1 - 0.1 12.7 0.2 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zinc_ribbon_4 PF13717.1 KFO97842.1 - 0.39 10.4 5.2 6.3 6.5 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO97842.1 - 1.3 8.8 4.6 2.8 7.8 3.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFO97842.1 - 1.8 8.2 8.9 6.9 6.3 0.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Abhydrolase_6 PF12697.2 KFO97843.1 - 4.8e-13 49.5 0.0 6.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO97843.1 - 7.8e-08 32.1 0.0 2.3e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFO97843.1 - 3.1e-07 30.2 0.0 4.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFO97843.1 - 0.0027 17.9 0.0 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.9 KFO97843.1 - 0.0056 15.2 0.0 0.0079 14.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family CUB PF00431.15 KFO97844.1 - 1e-15 57.7 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 CUB domain Sushi PF00084.15 KFO97844.1 - 1.2e-08 35.2 0.1 2.1e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Sushi domain (SCR repeat) CUB PF00431.15 KFO97845.1 - 1.1e-285 926.7 0.0 1.7e-27 95.6 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.15 KFO97845.1 - 1.2e-255 826.1 178.0 2.2e-11 43.9 0.8 27.6 27 0 0 27 27 27 27 Sushi domain (SCR repeat) CUB_2 PF02408.15 KFO97845.1 - 3.9e-22 78.0 10.2 0.004 16.6 0.0 10.7 12 0 0 12 12 12 6 CUB-like domain fn3 PF00041.16 KFO97846.1 - 1e-88 291.5 13.5 1.2e-18 67.0 0.1 6.0 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 KFO97846.1 - 4.2e-71 234.8 11.2 9.1e-22 76.7 0.0 8.4 9 0 0 9 9 9 7 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97846.1 - 1.4e-36 124.4 2.2 5.6e-08 32.7 0.0 7.2 7 0 0 7 7 7 5 Immunoglobulin domain Ig_3 PF13927.1 KFO97846.1 - 8.4e-25 87.0 2.7 3.5e-07 30.6 0.0 6.9 7 0 0 7 7 7 5 Immunoglobulin domain V-set PF07686.12 KFO97846.1 - 1.1e-22 80.0 12.8 2.1e-06 27.5 0.0 9.0 7 2 0 7 7 7 6 Immunoglobulin V-set domain ig PF00047.20 KFO97846.1 - 6.1e-18 64.6 13.6 1.9e-09 37.5 0.1 7.2 8 0 0 8 8 8 4 Immunoglobulin domain Tissue_fac PF01108.12 KFO97846.1 - 1.1e-10 41.1 1.4 0.0028 17.3 0.0 5.9 6 0 0 6 6 6 2 Tissue factor C2-set_2 PF08205.7 KFO97846.1 - 7.8e-09 35.3 0.1 0.13 12.1 0.0 4.5 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 KFO97846.1 - 3.6e-06 26.8 2.4 0.11 12.4 0.0 5.8 6 1 0 6 6 6 1 Natural killer cell receptor 2B4 RhoGEF PF00621.15 KFO97847.1 - 7.8e-43 146.4 1.2 1.8e-42 145.2 0.8 1.7 1 0 0 1 1 1 1 RhoGEF domain DUF3467 PF11950.3 KFO97847.1 - 0.014 15.4 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) XhlA PF10779.4 KFO97847.1 - 0.38 10.7 2.8 2.1 8.3 1.9 2.3 1 0 0 1 1 1 0 Haemolysin XhlA GKAP PF03359.8 KFO97848.1 - 1.1e-148 495.6 3.7 1.1e-148 495.6 2.6 2.6 3 0 0 3 3 3 1 Guanylate-kinase-associated protein (GKAP) protein DUF3381 PF11861.3 KFO97849.1 - 0.13 11.8 0.2 0.13 11.8 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3381) F-box PF00646.28 KFO97852.1 - 0.0025 17.4 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.6 KFO97852.1 - 0.0029 17.9 0.2 0.011 16.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.2 KFO97852.1 - 0.079 12.6 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 F-box-like HSCB_C PF07743.8 KFO97852.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain FAM110_C PF14160.1 KFO97854.1 - 8.2e-38 129.7 1.1 8.2e-38 129.7 0.8 2.6 3 0 0 3 3 3 1 Centrosome-associated C terminus FAM110_N PF14161.1 KFO97854.1 - 1.1e-22 80.3 0.2 1.1e-22 80.3 0.2 1.9 2 1 0 2 2 2 1 Centrosome-associated N terminus LMWPc PF01451.16 KFO97855.1 - 7.6e-42 142.9 0.0 8.5e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FAM150 PF15129.1 KFO97856.1 - 3.2e-60 201.3 0.9 3.9e-60 201.1 0.6 1.1 1 0 0 1 1 1 1 FAM150 family TMEM18 PF14770.1 KFO97857.1 - 2.7e-38 130.2 8.5 3.1e-38 130.0 5.9 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 PLD_C PF12357.3 KFO97857.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D C terminal Yae1_N PF09811.4 KFO97858.1 - 1.6e-12 46.7 40.0 0.00042 19.7 4.2 4.1 4 0 0 4 4 4 4 Essential protein Yae1, N terminal PDZ PF00595.19 KFO97859.1 - 2.5e-17 62.8 1.0 4.2e-17 62.0 0.7 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO97859.1 - 5.9e-06 26.0 0.2 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PH PF00169.24 KFO97859.1 - 0.00061 19.9 0.1 1.6 8.9 0.0 3.0 2 1 0 2 2 2 2 PH domain Tricorn_PDZ PF14685.1 KFO97859.1 - 0.024 14.3 0.5 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Tricorn protease PDZ domain An_peroxidase PF03098.10 KFO97860.1 - 6e-177 589.2 0.0 7.1e-177 588.9 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase EGF_CA PF07645.10 KFO97860.1 - 1.7e-08 34.3 7.0 1.7e-08 34.3 4.8 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 KFO97860.1 - 1.2e-05 25.2 7.5 4.3e-05 23.3 5.2 2.1 1 0 0 1 1 1 1 EGF domain FXa_inhibition PF14670.1 KFO97860.1 - 2.7e-05 24.2 7.7 2.7e-05 24.2 5.3 2.9 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site Sushi PF00084.15 KFO97860.1 - 0.00027 21.2 3.9 0.00027 21.2 2.7 3.1 3 0 0 3 3 3 1 Sushi domain (SCR repeat) cEGF PF12662.2 KFO97860.1 - 0.02 14.5 3.5 4.2 7.0 0.1 3.0 2 1 0 2 2 2 0 Complement Clr-like EGF-like An_peroxidase PF03098.10 KFO97861.1 - 9.7e-184 611.6 0.0 1.3e-183 611.2 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase I-set PF07679.11 KFO97861.1 - 3e-87 286.6 0.4 1.5e-20 72.8 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO97861.1 - 1.2e-55 185.5 3.8 8.7e-14 51.4 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain LRR_8 PF13855.1 KFO97861.1 - 2.1e-51 171.4 30.0 1.4e-17 63.2 2.3 3.8 1 1 3 4 4 4 4 Leucine rich repeat Ig_3 PF13927.1 KFO97861.1 - 9.2e-42 141.3 4.2 3.7e-11 43.3 0.2 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.20 KFO97861.1 - 7.1e-35 118.9 0.9 5.2e-12 45.7 0.0 4.9 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 KFO97861.1 - 2.3e-32 111.2 0.7 6.6e-08 32.4 0.0 5.2 4 1 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO97861.1 - 5.8e-19 67.7 3.3 0.0011 18.7 0.0 4.6 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain LRR_4 PF12799.2 KFO97861.1 - 8.1e-18 63.6 15.0 1e-07 31.3 0.0 4.7 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFO97861.1 - 1.4e-11 44.1 2.0 7.6e-10 38.5 0.0 2.7 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) VWC PF00093.13 KFO97861.1 - 3.5e-09 36.6 18.6 3.5e-09 36.6 12.9 2.9 3 0 0 3 3 2 1 von Willebrand factor type C domain LRR_1 PF00560.28 KFO97861.1 - 4.1e-08 32.1 14.2 2 8.7 0.1 7.0 6 0 0 6 6 5 4 Leucine Rich Repeat Sp38 PF07354.7 KFO97861.1 - 8.9e-07 27.8 0.0 0.049 12.2 0.0 3.3 3 0 0 3 3 3 2 Zona-pellucida-binding protein (Sp38) LRR_9 PF14580.1 KFO97861.1 - 2.8e-06 26.9 0.8 0.00054 19.5 0.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat PSP94 PF05825.6 KFO97861.1 - 0.0013 18.9 8.6 0.0037 17.4 5.9 1.7 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) LRR_7 PF13504.1 KFO97861.1 - 0.016 15.3 10.4 39 5.0 0.0 6.0 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KFO97861.1 - 0.14 12.2 7.0 70 3.9 0.6 5.8 6 1 1 7 7 4 0 Leucine Rich repeat UPF0220 PF05255.6 KFO97861.1 - 0.38 9.9 0.0 0.69 9.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) WD40 PF00400.27 KFO97862.1 - 1.8e-22 78.3 8.3 5e-07 29.3 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat YmzC PF14157.1 KFO97862.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.9 3 0 0 3 3 3 0 YmzC-like protein TPR_11 PF13414.1 KFO97863.1 - 7.5e-16 57.5 0.0 9.2e-08 31.6 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFO97863.1 - 2.6e-13 48.7 0.0 0.0086 15.9 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFO97863.1 - 3e-11 42.4 0.0 0.0019 17.7 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97863.1 - 8.4e-10 38.8 0.1 5.1e-05 23.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97863.1 - 6.8e-09 36.1 0.0 0.0026 18.3 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO97863.1 - 1.6e-08 34.3 0.6 0.00084 19.2 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFO97863.1 - 6.7e-06 26.2 0.2 0.0073 16.6 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFO97863.1 - 1.3e-05 25.3 0.0 7.3 7.5 0.0 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.9 KFO97863.1 - 0.00012 21.3 0.2 0.00031 20.0 0.1 1.7 2 0 0 2 2 2 1 Coatomer epsilon subunit Apc3 PF12895.2 KFO97863.1 - 0.00014 21.9 2.2 0.11 12.6 0.1 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFO97863.1 - 0.0053 16.4 0.0 3.4 7.7 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFO97863.1 - 0.0057 16.7 0.5 2.2 8.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFO97863.1 - 0.0066 16.1 0.0 1 9.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Phage_tail_X PF05489.7 KFO97863.1 - 0.15 11.5 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X ARD PF03079.9 KFO97864.1 - 8.7e-60 201.2 0.2 1e-59 201.0 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KFO97864.1 - 1.9e-08 33.7 0.0 3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KFO97864.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KFO97864.1 - 0.027 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.1 KFO97864.1 - 0.062 12.7 0.0 0.16 11.4 0.0 1.7 1 1 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.7 KFO97864.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RNase_H PF00075.19 KFO97865.1 - 8.2e-36 123.2 0.0 1.3e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 KFO97865.1 - 4e-18 65.1 0.8 1.1e-17 63.7 0.6 1.8 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.1 KFO97865.1 - 0.00031 20.4 0.0 0.027 14.2 0.0 2.9 3 0 0 3 3 3 1 Reverse transcriptase-like Ribosomal_S7e PF01251.13 KFO97866.1 - 3.7e-92 307.0 4.3 4.2e-92 306.8 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Lectin_C PF00059.16 KFO97867.1 - 5.2e-16 59.2 0.1 8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Lectin C-type domain Collagen PF01391.13 KFO97867.1 - 1.1e-14 53.6 53.5 2.6e-09 36.4 17.2 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) WD40 PF00400.27 KFO97868.1 - 1.7e-21 75.2 8.3 5.6e-09 35.5 0.4 4.0 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KFO97868.1 - 3e-09 35.5 2.5 0.016 13.3 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFO97868.1 - 0.00024 20.6 0.5 0.0016 17.9 0.1 2.2 1 1 0 1 1 1 1 PQQ-like domain CDtoxinA PF03498.9 KFO97868.1 - 0.018 14.3 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family BBS2_Mid PF14783.1 KFO97868.1 - 0.021 14.5 0.0 1.3 8.8 0.0 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 KFO97868.1 - 0.05 12.3 0.2 0.86 8.2 0.0 2.3 1 1 2 3 3 3 0 Nup133 N terminal like Ank PF00023.25 KFO97869.1 - 4.1e-31 105.2 1.7 1.7e-09 36.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFO97869.1 - 3.8e-28 97.6 0.7 2e-23 82.5 0.3 1.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFO97869.1 - 2e-22 78.6 4.8 1.6e-10 40.8 0.2 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 KFO97869.1 - 2.7e-21 75.7 0.0 9.9e-19 67.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.1 KFO97869.1 - 5.8e-21 72.4 0.3 1.4e-06 27.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFO97869.1 - 1.5e-18 66.7 1.7 5.7e-11 42.6 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Pkinase PF00069.20 KFO97869.1 - 2e-14 53.3 0.0 1.5e-06 27.5 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pro-kuma_activ PF09286.6 KFO97870.1 - 6.5e-20 71.6 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KFO97870.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Subtilase family LCM PF04072.9 KFO97871.1 - 4.8e-28 97.9 0.0 6.5e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KFO97871.1 - 1e-11 44.3 3.8 0.66 9.7 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO97871.1 - 2.7e-11 43.1 0.2 0.16 11.9 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFO97871.1 - 7.5e-10 38.5 2.3 0.0012 18.9 0.0 5.4 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 KFO97871.1 - 1e-07 31.4 4.8 0.16 11.8 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 KFO97871.1 - 1.2e-05 25.2 9.1 0.015 15.4 0.0 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.20 KFO97871.1 - 3.1e-05 23.4 0.2 0.11 12.0 0.0 4.2 4 0 0 4 4 4 1 Kelch motif RAG2 PF03089.9 KFO97871.1 - 0.021 13.5 0.1 1.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Recombination activating protein 2 Glyoxal_oxid_N PF07250.6 KFO97871.1 - 0.16 10.9 0.1 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus dUTPase PF00692.14 KFO97872.1 - 4.9e-23 81.0 0.1 6.3e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFO97872.1 - 0.0093 15.8 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease CS PF04969.11 KFO97875.1 - 2.2e-18 66.5 0.5 6e-18 65.1 0.2 1.8 2 0 0 2 2 2 1 CS domain EnY2 PF10163.4 KFO97876.1 - 4.9e-35 119.3 0.4 5.5e-35 119.1 0.3 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 SAP PF02037.22 KFO97876.1 - 7.2 6.2 6.4 15 5.2 0.0 3.6 4 0 0 4 4 4 0 SAP domain DUF1682 PF07946.9 KFO97877.1 - 8.4 5.1 15.8 12 4.6 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Syntaphilin PF15290.1 KFO97878.1 - 1.4e-117 392.5 16.0 2.4e-117 391.7 11.1 1.4 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp DUF812 PF05667.6 KFO97878.1 - 8.8e-05 21.2 7.6 0.00015 20.4 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) MAD PF05557.8 KFO97878.1 - 0.00025 19.2 18.3 0.00038 18.7 12.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein IncA PF04156.9 KFO97878.1 - 0.025 14.2 11.6 0.051 13.1 8.1 1.5 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 KFO97878.1 - 0.044 11.1 9.3 0.061 10.6 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_27 PF13514.1 KFO97878.1 - 0.065 10.9 8.9 0.099 10.3 6.2 1.2 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 KFO97878.1 - 0.14 11.2 3.9 0.21 10.7 2.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.4 KFO97878.1 - 0.17 10.1 15.3 0.32 9.2 10.6 1.5 1 0 0 1 1 1 0 Transmembrane protein AAA_13 PF13166.1 KFO97878.1 - 0.19 10.1 9.8 0.35 9.2 6.8 1.3 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 KFO97878.1 - 0.2 10.2 15.1 0.38 9.3 10.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec8_exocyst PF04048.9 KFO97878.1 - 0.36 10.4 11.4 1 9.0 0.5 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain GAS PF13851.1 KFO97878.1 - 0.46 9.6 19.9 0.13 11.4 11.7 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 KFO97878.1 - 0.47 9.3 13.6 0.82 8.5 9.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BTV_NS2 PF04514.7 KFO97878.1 - 0.53 9.1 8.2 0.23 10.2 4.1 1.4 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 HR1 PF02185.11 KFO97878.1 - 2.6 7.8 13.3 1.6 8.5 1.1 2.7 2 1 0 2 2 2 0 Hr1 repeat TPR_MLP1_2 PF07926.7 KFO97878.1 - 3.7 7.2 20.1 70 3.1 13.9 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 KFO97878.1 - 3.7 5.8 13.0 5.5 5.2 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF641 PF04859.7 KFO97878.1 - 4 7.1 13.9 6.6 6.5 2.0 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin PF02996.12 KFO97878.1 - 4.1 7.0 12.2 7.5 6.2 1.1 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.1 KFO97878.1 - 6.2 6.7 21.6 3.2 7.7 5.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF945 PF06097.6 KFO97879.1 - 1.3e-15 57.2 0.0 0.071 11.8 0.0 8.3 5 2 1 8 8 8 6 Bacterial protein of unknown function (DUF945) DUF490 PF04357.8 KFO97879.1 - 2.6e-07 30.1 12.2 2.3 7.2 0.0 8.2 4 1 3 8 8 8 3 Family of unknown function (DUF490) AsmA_1 PF13109.1 KFO97879.1 - 0.018 14.2 0.1 9.2 5.4 0.0 4.6 4 0 0 4 4 4 0 AsmA-like C-terminal region Coa1 PF08695.5 KFO97879.1 - 0.18 11.3 0.0 89 2.6 0.0 5.3 9 0 0 9 9 9 0 Cytochrome oxidase complex assembly protein 1 DUF2045 PF09741.4 KFO97879.1 - 0.59 9.2 2.1 1.8e+02 1.0 0.0 5.4 9 0 0 9 9 9 0 Uncharacterized conserved protein (DUF2045) DNA_pol3_alpha PF07733.7 KFO97879.1 - 1.1 7.6 4.3 58 1.9 0.0 4.5 6 0 0 6 6 6 0 Bacterial DNA polymerase III alpha subunit Rhabdo_glycop PF00974.13 KFO97879.1 - 5.8 5.0 4.9 1.8e+02 0.0 0.0 4.3 5 0 0 5 5 5 0 Rhabdovirus spike glycoprotein PDZ PF00595.19 KFO97880.1 - 2.8e-08 33.8 0.1 1.9e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO97880.1 - 4.8e-06 26.3 0.3 8.4e-06 25.5 0.2 1.4 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFO97880.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Pkinase_Tyr PF07714.12 KFO97882.1 - 8e-96 320.0 0.0 1.3e-95 319.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFO97882.1 - 4.5e-79 264.3 0.3 8.9e-79 263.3 0.2 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFO97882.1 - 3.8e-46 157.3 0.0 7.5e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFO97882.1 - 1.2e-29 102.2 8.8 1.8e-15 56.7 0.9 3.7 4 0 0 4 4 4 2 Fibronectin type III domain SAM_1 PF00536.25 KFO97882.1 - 1.2e-23 83.0 0.0 2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 KFO97882.1 - 1.3e-23 83.1 0.0 2.8e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_2 PF07647.12 KFO97882.1 - 4.4e-21 74.5 0.0 8.4e-21 73.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GCC2_GCC3 PF07699.8 KFO97882.1 - 3.6e-06 26.4 9.6 3.6e-06 26.4 6.6 2.7 2 0 0 2 2 2 1 GCC2 and GCC3 Tissue_fac PF01108.12 KFO97882.1 - 0.00013 21.6 0.4 0.035 13.8 0.0 2.6 2 0 0 2 2 2 1 Tissue factor SusE PF14292.1 KFO97882.1 - 0.0011 18.7 0.2 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 SusE outer membrane protein CD34_antigen PF06365.7 KFO97882.1 - 0.0013 18.4 0.0 0.0043 16.7 0.0 1.8 2 0 0 2 2 2 1 CD34/Podocalyxin family Interfer-bind PF09294.5 KFO97882.1 - 0.0019 18.1 0.3 0.044 13.8 0.1 2.8 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III DUF2318 PF10080.4 KFO97882.1 - 0.059 13.1 3.4 0.18 11.5 2.4 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Yae1_N PF09811.4 KFO97883.1 - 2.7e-19 68.3 52.4 0.00017 21.0 6.3 5.3 1 1 2 3 3 3 3 Essential protein Yae1, N terminal GIDA PF01134.17 KFO97884.1 - 6.7e-96 321.5 0.0 9.1e-96 321.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KFO97884.1 - 1.4e-19 69.9 0.0 2.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 GidA associated domain 3 Hexapep_2 PF14602.1 KFO97884.1 - 0.024 14.1 0.7 0.048 13.2 0.5 1.4 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 KFO97884.1 - 0.044 13.3 0.5 0.1 12.1 0.4 1.6 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) Mab-21 PF03281.9 KFO97885.1 - 1.9e-60 204.4 2.8 2.2e-60 204.3 2.0 1.0 1 0 0 1 1 1 1 Mab-21 protein DEAD PF00270.24 KFO97886.1 - 5.4e-36 123.6 0.0 2.9e-35 121.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO97886.1 - 4.2e-26 90.6 0.1 3.1e-25 87.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain KH_1 PF00013.24 KFO97886.1 - 0.00039 19.9 0.1 0.0013 18.3 0.1 1.8 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFO97886.1 - 0.00075 19.0 1.1 0.0017 17.9 0.7 1.6 1 0 0 1 1 1 1 KH domain Ppx-GppA PF02541.11 KFO97886.1 - 0.012 14.8 0.1 0.051 12.7 0.0 1.9 2 0 0 2 2 2 0 Ppx/GppA phosphatase family ResIII PF04851.10 KFO97886.1 - 0.016 15.0 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4217 PF13959.1 KFO97886.1 - 0.11 12.0 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) KCNQ_channel PF03520.9 KFO97887.1 - 2.3e-91 304.6 2.1 5.1e-91 303.4 1.5 1.6 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.26 KFO97887.1 - 8.7e-26 90.4 11.1 1.7e-25 89.4 7.7 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFO97887.1 - 1.5e-13 50.2 5.8 4.3e-13 48.7 4.0 1.8 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.7 KFO97887.1 - 0.058 11.8 3.4 0.025 13.0 0.5 1.7 1 1 1 2 2 2 0 Polycystin cation channel IQ PF00612.22 KFO97887.1 - 0.47 10.2 0.1 0.47 10.2 0.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Cornifin PF02389.10 KFO97889.1 - 7 6.3 34.5 44 3.7 23.9 1.9 1 1 0 1 1 1 0 Cornifin (SPRR) family DUF3070 PF11270.3 KFO97889.1 - 7.9 6.3 14.2 29 4.5 0.2 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3070) EF-hand_4 PF12763.2 KFO97891.1 - 2.4e-18 65.7 0.0 1.1e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFO97891.1 - 0.0015 17.7 0.1 0.0053 15.9 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFO97891.1 - 0.0032 17.0 0.5 1.6 8.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 KFO97891.1 - 0.0095 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin family EF-hand_5 PF13202.1 KFO97891.1 - 0.042 13.1 0.1 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 EF hand Gtr1_RagA PF04670.7 KFO97891.1 - 0.05 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region EF-hand_7 PF13499.1 KFO97891.1 - 0.06 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair GTP_EFTU PF00009.22 KFO97891.1 - 0.081 12.3 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.1 KFO97891.1 - 0.11 12.4 0.0 0.41 10.6 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Connexin PF00029.14 KFO97892.1 - 5.1e-36 122.9 2.8 5.1e-36 122.9 1.9 1.8 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFO97892.1 - 4.2e-31 106.5 1.3 4.2e-31 106.5 0.9 2.0 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain 7tm_4 PF13853.1 KFO97893.1 - 2.3e-33 115.0 4.5 2.5e-33 114.8 3.2 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO97893.1 - 0.011 14.9 3.8 0.012 14.7 2.7 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.1 KFO97893.1 - 0.3 11.0 1.2 0.49 10.3 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) IMD PF08397.6 KFO97894.1 - 1.5e-90 302.3 4.7 1.8e-90 302.0 3.3 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.1 KFO97894.1 - 3.5e-11 42.5 0.0 6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO97894.1 - 1.4e-07 30.9 0.0 2.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFO97894.1 - 1.4e-06 27.5 0.0 2.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain DUF3510 PF12022.3 KFO97894.1 - 0.0086 16.1 4.0 0.02 15.0 2.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) NusB PF01029.13 KFO97894.1 - 0.41 10.6 2.7 0.76 9.7 1.9 1.3 1 0 0 1 1 1 0 NusB family DUF2367 PF10164.4 KFO97895.1 - 1.2e-30 105.2 5.5 1.3e-30 105.1 3.8 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF2636 PF11120.3 KFO97895.1 - 0.0065 15.9 1.5 0.01 15.3 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2636) zf-ribbon_3 PF13248.1 KFO97895.1 - 0.028 13.6 5.0 0.046 12.9 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 KFO97895.1 - 0.043 13.4 1.5 4.2 7.0 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 KFO97895.1 - 0.059 13.0 6.1 0.27 10.9 4.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 KFO97895.1 - 0.063 12.7 1.3 0.32 10.5 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFO97895.1 - 0.11 12.5 0.7 15 5.6 0.1 2.3 2 0 0 2 2 2 0 zinc-finger DUF1936 PF09151.5 KFO97895.1 - 0.18 11.3 4.9 0.97 8.9 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) zf-nanos PF05741.8 KFO97895.1 - 0.21 11.6 1.1 0.3 11.0 0.2 1.7 2 0 0 2 2 2 0 Nanos RNA binding domain zinc_ribbon_5 PF13719.1 KFO97895.1 - 1.1 8.9 3.6 1 8.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KFO97895.1 - 2.6 7.6 6.7 0.54 9.8 0.8 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF35_N PF12172.3 KFO97895.1 - 6.4 6.8 8.0 7.6 6.5 2.4 2.6 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Hyd_WA PF06462.7 KFO97896.1 - 9.7e-87 284.2 60.9 1.5e-13 50.1 1.3 12.1 12 0 0 12 12 12 10 Propeller Pex24p PF06398.6 KFO97896.1 - 9.8e-23 80.5 21.6 2.6e-12 46.2 3.3 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin HLH PF00010.21 KFO97897.1 - 1.1e-16 60.1 3.7 1.1e-16 60.1 2.6 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RepB PF07506.6 KFO97897.1 - 0.018 14.8 1.8 0.025 14.4 1.3 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein Myotub-related PF06602.9 KFO97897.1 - 0.096 11.4 1.9 0.11 11.2 1.3 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain HemY_N PF07219.8 KFO97897.1 - 0.6 9.6 2.8 1 8.9 2.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Ribosomal_L19e PF01280.15 KFO97897.1 - 1.7 8.3 12.2 1.7 8.3 7.4 1.7 1 1 1 2 2 2 0 Ribosomal protein L19e Pkinase_Tyr PF07714.12 KFO97898.1 - 3.7e-55 186.8 0.0 5.3e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO97898.1 - 2.8e-30 105.3 0.0 5.9e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain FAM163 PF15069.1 KFO97898.1 - 0.049 14.2 0.0 0.36 11.3 0.0 2.5 1 0 0 1 1 1 0 FAM163 family Kinase-like PF14531.1 KFO97898.1 - 0.075 11.9 0.0 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like ACI44 PF15270.1 KFO97898.1 - 0.18 11.8 7.6 8.5 6.4 1.1 3.6 3 0 0 3 3 3 0 Metallo-carboxypeptidase inhibitor EF-hand_1 PF00036.27 KFO97899.1 - 4.7e-13 47.4 1.7 1.8e-05 23.7 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFO97899.1 - 3.3e-11 42.0 1.2 2.4e-05 23.8 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KFO97899.1 - 1.9e-10 40.7 0.1 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFO97899.1 - 2.7e-10 39.0 2.4 6.5e-05 22.1 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFO97899.1 - 1e-09 37.8 1.0 3.8e-08 32.8 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO97899.1 - 0.0026 17.7 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_1 PF00036.27 KFO97900.1 - 1.9e-12 45.4 2.1 2.1e-05 23.4 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFO97900.1 - 1.6e-10 40.9 0.2 2.1e-10 40.5 0.1 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFO97900.1 - 2.4e-10 39.3 1.9 4.5e-05 22.9 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFO97900.1 - 1.2e-09 37.5 1.2 4.6e-08 32.5 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFO97900.1 - 3.9e-09 35.4 3.5 0.00041 19.5 0.1 2.3 2 0 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.5 KFO97900.1 - 0.0051 16.7 0.3 0.21 11.5 0.1 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.4 KFO97900.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region QueF_N PF14819.1 KFO97900.1 - 0.05 13.7 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term EF-hand_1 PF00036.27 KFO97901.1 - 4.7e-14 50.5 2.4 6.5e-07 28.2 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFO97901.1 - 1.2e-13 50.9 0.6 1.9e-13 50.3 0.4 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFO97901.1 - 4.6e-12 44.7 2.3 1.6e-06 27.4 0.4 2.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFO97901.1 - 6.7e-10 37.8 2.8 0.0002 20.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFO97901.1 - 3.1e-09 36.3 0.9 0.00013 21.5 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO97901.1 - 0.0089 16.0 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KFO97901.1 - 0.019 14.5 2.8 0.1 12.2 0.4 2.5 2 1 0 2 2 2 0 EF hand DUF1712 PF08217.6 KFO97902.1 - 7.5e-96 321.7 8.6 3.5e-86 289.7 0.9 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) MORN PF02493.15 KFO97903.1 - 1.1e-17 62.6 31.9 7e-08 31.7 0.9 5.4 5 1 0 5 5 5 5 MORN repeat DUF2610 PF11020.3 KFO97903.1 - 0.099 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) MutL_C PF08676.6 KFO97904.1 - 8.1e-28 96.8 0.0 2.3e-27 95.3 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KFO97904.1 - 5.4e-24 83.9 0.2 3.8e-23 81.2 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFO97904.1 - 4.3e-13 49.0 0.1 1.3e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFO97904.1 - 1.7e-11 43.8 0.1 5.9e-11 42.0 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GST_C_3 PF14497.1 KFO97905.1 - 7.4e-07 29.5 0.3 1.7e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFO97905.1 - 8.6e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFO97905.1 - 0.00017 21.4 0.1 0.00047 20.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Potex_coat PF06184.6 KFO97905.1 - 0.095 12.0 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Potexvirus coat protein Matrilin_ccoil PF10393.4 KFO97905.1 - 0.15 11.4 1.1 0.24 10.7 0.2 1.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Pkinase PF00069.20 KFO97906.1 - 4.8e-45 153.7 1.1 8.3e-30 103.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97906.1 - 8.5e-26 90.5 1.5 1e-18 67.3 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF641 PF04859.7 KFO97906.1 - 0.0072 16.0 1.5 0.016 14.9 1.1 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) SlyX PF04102.7 KFO97906.1 - 0.017 15.5 2.2 0.068 13.5 1.5 2.0 1 0 0 1 1 1 0 SlyX P4Ha_N PF08336.6 KFO97906.1 - 0.054 13.3 1.5 0.12 12.1 1.1 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DivIC PF04977.10 KFO97906.1 - 0.33 10.4 4.5 0.22 11.0 1.5 1.9 2 0 0 2 2 2 0 Septum formation initiator UCH PF00443.24 KFO97907.1 - 2.7e-54 184.0 1.5 2.7e-54 184.0 1.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO97907.1 - 1.6e-26 93.4 0.4 1.6e-26 93.4 0.3 3.6 4 0 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase Sec7 PF01369.15 KFO97908.1 - 9.1e-64 214.6 0.0 1.2e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KFO97908.1 - 1.5e-24 86.1 0.0 2.3e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFO97908.1 - 4.7e-07 30.0 0.7 3.2e-06 27.3 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFO97908.1 - 0.013 15.3 0.0 0.041 13.7 0.0 1.9 1 1 0 1 1 1 0 PH domain PH_8 PF15409.1 KFO97908.1 - 0.027 14.5 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.1 KFO97908.1 - 0.14 12.2 0.0 20 5.2 0.0 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain CTDII PF01556.13 KFO97909.1 - 3e-21 75.1 0.2 2.7e-18 65.6 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain Mito_carr PF00153.22 KFO97910.1 - 7.2e-59 195.5 4.8 2.1e-23 81.8 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 KFO97910.1 - 0.031 14.1 0.6 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 Colicin V production protein Glyco_transf_7N PF13733.1 KFO97911.1 - 2e-45 153.5 0.0 2.9e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFO97911.1 - 2.4e-28 97.3 0.5 4.1e-28 96.6 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFO97911.1 - 6.2e-07 28.7 0.2 0.00061 18.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Na_H_Exchanger PF00999.16 KFO97912.1 - 8.1e-59 199.0 39.8 1e-58 198.6 27.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3995 PF13160.1 KFO97912.1 - 5.3 7.1 9.8 1.7 8.7 0.2 3.6 4 2 0 4 4 4 0 Protein of unknown function (DUF3995) PUB PF09409.5 KFO97913.1 - 0.0035 17.0 0.0 0.0086 15.8 0.0 1.7 1 0 0 1 1 1 1 PUB domain zf-Di19 PF05605.7 KFO97914.1 - 1e-18 67.1 2.1 1e-18 67.1 1.4 3.2 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DND1_DSRM PF14709.1 KFO97914.1 - 0.02 15.1 0.0 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DYW_deaminase PF14432.1 KFO97914.1 - 0.056 13.4 0.4 5.3 7.0 0.0 2.6 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases zf-DNA_Pol PF08996.5 KFO97914.1 - 0.067 12.5 8.9 0.23 10.7 0.1 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Methyltransf_15 PF09445.5 KFO97914.1 - 0.073 12.6 0.3 0.093 12.2 0.2 1.3 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase zf-C2H2 PF00096.21 KFO97914.1 - 0.073 13.4 0.9 0.073 13.4 0.6 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type DZR PF12773.2 KFO97914.1 - 0.079 12.7 17.8 0.15 11.8 0.7 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-BED PF02892.10 KFO97914.1 - 0.18 11.5 0.1 0.18 11.5 0.1 3.7 3 1 1 4 4 4 0 BED zinc finger YdjO PF14169.1 KFO97914.1 - 0.23 10.9 7.0 1.3 8.5 0.0 3.8 4 0 0 4 4 4 0 Cold-inducible protein YdjO zf-C2H2_4 PF13894.1 KFO97914.1 - 0.31 11.4 14.8 0.3 11.5 0.7 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO97914.1 - 0.4 11.0 0.1 0.4 11.0 0.1 4.5 5 0 0 5 5 5 0 Zinc-finger double domain tRNA-synt_1g PF09334.6 KFO97914.1 - 0.68 8.5 5.1 2.8 6.5 3.2 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (M) RRN7 PF11781.3 KFO97914.1 - 0.89 9.1 7.2 2.7 7.5 0.0 3.5 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 YgbA_NO PF11756.3 KFO97914.1 - 5.2 7.1 11.5 5.5 7.0 4.6 2.4 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter DUF3795 PF12675.2 KFO97914.1 - 6 7.1 14.4 1.4 9.1 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) zf-C2H2 PF00096.21 KFO97915.1 - 2.4e-23 81.0 37.0 7e-06 26.0 0.5 5.2 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO97915.1 - 4e-21 74.1 28.9 2.9e-08 33.5 0.2 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFO97915.1 - 2.9e-14 52.6 21.8 0.00026 21.0 0.7 5.4 4 1 1 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFO97915.1 - 1e-13 50.5 33.4 0.0011 19.0 0.5 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO97915.1 - 3.1e-10 39.5 32.3 0.00062 19.5 0.2 5.4 5 1 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 KFO97915.1 - 4.6e-08 33.0 18.2 0.0057 16.8 0.7 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFO97915.1 - 5.6e-05 23.1 18.2 0.039 14.0 1.0 3.5 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KFO97915.1 - 0.00093 18.9 30.8 0.3 10.8 1.9 5.2 2 2 3 5 5 5 3 BED zinc finger zf-C2H2_2 PF12756.2 KFO97915.1 - 0.0026 17.8 22.5 0.76 9.9 0.8 4.9 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 KFO97915.1 - 0.0041 17.0 24.5 0.47 10.4 0.5 4.8 4 1 0 4 4 4 2 Zinc ribbon domain Rpr2 PF04032.11 KFO97915.1 - 0.0044 16.8 15.4 0.02 14.7 0.5 2.6 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HC_2 PF13913.1 KFO97915.1 - 0.018 14.7 13.9 0.25 11.0 0.4 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 KFO97915.1 - 0.37 10.9 24.6 0.093 12.9 2.7 2.6 2 1 0 2 2 2 0 CHY zinc finger zf-HYPF PF07503.7 KFO97915.1 - 2.2 7.7 15.0 3.4 7.1 1.3 3.9 4 1 0 4 4 4 0 HypF finger zf-AN1 PF01428.11 KFO97915.1 - 2.2 8.2 22.5 12 5.9 0.1 5.1 5 0 0 5 5 5 0 AN1-like Zinc finger DUF2180 PF09947.4 KFO97915.1 - 3 7.6 8.9 0.87 9.3 1.8 2.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) PyrI_C PF02748.10 KFO97915.1 - 5.3 6.5 19.2 2.4 7.6 2.2 4.4 3 2 2 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.4 KFO97915.1 - 5.7 6.8 12.4 8.3 6.3 0.9 4.1 4 0 0 4 4 4 0 Zinc-finger domain Zn_Tnp_IS1595 PF12760.2 KFO97915.1 - 5.7 6.8 31.4 2.2 8.1 3.2 3.9 2 2 1 4 4 4 0 Transposase zinc-ribbon domain RRN7 PF11781.3 KFO97915.1 - 6 6.4 8.5 18 4.8 0.1 3.7 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 PHD PF00628.24 KFO97915.1 - 7.5 6.3 16.6 20 4.9 4.4 4.1 3 1 0 3 3 3 0 PHD-finger Kua-UEV1_localn PF10520.4 KFO97916.1 - 4.1e-31 108.0 2.5 5.8e-31 107.5 1.7 1.2 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain UQ_con PF00179.21 KFO97916.1 - 1.9e-18 66.2 0.0 3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFO97916.1 - 0.0023 17.7 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain Cmyb_C PF09316.5 KFO97917.1 - 7.2e-64 214.4 5.7 2.1e-63 212.9 3.9 1.8 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.26 KFO97917.1 - 4.2e-47 157.9 16.6 3.3e-16 59.0 2.7 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFO97917.1 - 5.8e-47 157.6 15.2 2.2e-20 72.5 0.6 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 KFO97917.1 - 0.001 18.4 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Rap1_C PF11626.3 KFO97917.1 - 0.11 12.3 7.9 17 5.3 2.7 3.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KFO97917.1 - 3.3 7.5 5.7 19 5.1 0.1 3.4 1 1 2 3 3 3 0 Rap1 Myb domain zf-C3HC4 PF00097.20 KFO97918.1 - 0.11 12.2 2.9 0.2 11.3 2.0 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO97918.1 - 0.13 12.1 2.4 2.1 8.2 2.2 1.9 1 1 1 2 2 2 0 Ring finger domain ABC_transp_aux PF09822.4 KFO97919.1 - 2.4e-09 37.0 0.0 1.8e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 ABC-type uncharacterized transport system DUF4159 PF13709.1 KFO97919.1 - 0.031 13.3 0.1 0.16 11.0 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4159) Pkinase PF00069.20 KFO97920.1 - 9.4e-71 237.9 0.0 1.1e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO97920.1 - 1.8e-35 122.2 0.0 2.2e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFO97920.1 - 8.4e-06 26.2 0.1 1.5e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFO97920.1 - 2e-05 23.7 0.0 5.2e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO97920.1 - 0.00049 19.2 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO97920.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aa_trans PF01490.13 KFO97921.1 - 4e-98 328.5 19.1 4.7e-98 328.3 13.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.22 KFO97922.1 - 9e-43 145.5 0.4 9e-43 145.5 0.3 2.0 2 1 0 2 2 2 1 RhoGAP domain Actin PF00022.14 KFO97923.1 - 8.8e-44 149.5 0.0 4.9e-27 94.3 0.0 2.2 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KFO97923.1 - 0.19 10.3 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein PDDEXK_1 PF12705.2 KFO97923.1 - 1.2 8.4 6.4 1.8 7.9 3.9 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF1669 PF07894.7 KFO97924.1 - 1.5e-81 273.6 0.0 2.3e-81 273.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFO97924.1 - 8.6e-07 28.7 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain DUF1669 PF07894.7 KFO97925.1 - 6.8e-40 137.0 0.5 1.4e-27 96.6 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFO97925.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain DUF3023 PF11224.3 KFO97925.1 - 0.061 12.9 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) Gcd10p PF04189.8 KFO97925.1 - 0.087 11.9 0.0 0.11 11.5 0.0 1.3 1 1 0 1 1 1 0 Gcd10p family OB_NTP_bind PF07717.11 KFO97926.1 - 1.1e-27 96.0 0.0 2.4e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFO97926.1 - 6.7e-25 87.0 0.1 1.9e-24 85.6 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFO97926.1 - 4.2e-15 55.3 0.0 9.3e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 KFO97926.1 - 0.0001 22.6 0.2 0.031 14.5 0.0 2.7 1 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 KFO97926.1 - 0.0022 18.1 0.1 0.013 15.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain UPF0203 PF05254.7 KFO97926.1 - 0.078 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) 14-3-3 PF00244.15 KFO97927.1 - 1.5e-112 374.4 11.9 1.7e-112 374.2 8.3 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.10 KFO97927.1 - 0.042 13.5 0.2 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DUF4303 PF14136.1 KFO97927.1 - 0.11 12.1 2.6 2.6 7.6 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) DUF3802 PF12290.3 KFO97927.1 - 0.22 11.8 2.3 39 4.6 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3802) CCDC-167 PF15188.1 KFO97927.1 - 0.85 9.6 5.8 0.52 10.3 0.4 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Drf_FH3 PF06367.11 KFO97927.1 - 1.6 8.0 5.6 0.26 10.6 0.8 2.0 3 0 0 3 3 3 0 Diaphanous FH3 Domain TPR_11 PF13414.1 KFO97928.1 - 6.9e-31 105.7 14.2 2.4e-17 62.3 2.7 2.2 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFO97928.1 - 1.4e-19 68.7 8.1 9.5e-11 40.8 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFO97928.1 - 1.5e-17 62.0 5.7 9.1e-08 31.4 0.2 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFO97928.1 - 5.6e-14 52.3 0.7 2e-07 31.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO97928.1 - 1.2e-09 37.9 0.5 0.00023 21.5 0.4 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFO97928.1 - 3.5e-08 32.6 10.4 4.3e-05 22.9 0.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO97928.1 - 9.1e-08 31.9 6.5 1.5e-06 28.0 1.9 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFO97928.1 - 1.1e-07 31.5 4.6 0.00047 20.1 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFO97928.1 - 1.7e-07 31.4 8.0 9.1e-06 25.9 3.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFO97928.1 - 2.5e-06 27.2 2.8 0.00037 20.2 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFO97928.1 - 5.2e-06 26.2 6.3 0.0031 17.3 0.3 3.1 2 1 2 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 KFO97928.1 - 6.9e-05 22.9 9.3 0.00012 22.1 6.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFO97928.1 - 0.0002 21.5 6.4 0.21 12.1 0.3 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KFO97928.1 - 0.00051 20.3 0.9 0.00097 19.4 0.6 1.5 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_7 PF13176.1 KFO97928.1 - 0.00087 18.9 1.4 0.45 10.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 KFO97928.1 - 0.0081 16.0 8.8 0.35 10.7 1.0 2.4 1 1 1 2 2 2 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 KFO97928.1 - 0.033 13.4 4.1 2.1 7.6 0.0 3.3 4 0 0 4 4 4 0 SHNi-TPR Sec8_exocyst PF04048.9 KFO97928.1 - 0.035 13.7 0.4 0.048 13.2 0.3 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain PaREP1 PF05942.6 KFO97928.1 - 0.14 12.0 3.7 0.3 10.9 2.5 1.7 1 1 0 1 1 1 0 Archaeal PaREP1/PaREP8 family TPR_10 PF13374.1 KFO97928.1 - 6.1 6.9 7.8 1.5 8.8 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Ion_trans PF00520.26 KFO97929.1 - 2.6e-32 111.7 2.4 6e-32 110.5 0.4 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFO97929.1 - 2e-30 104.8 0.1 4.7e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFO97929.1 - 3.8e-10 39.3 4.8 3.8e-10 39.3 3.3 2.6 3 0 0 3 3 3 1 Ion channel VWA PF00092.23 KFO97930.1 - 3.8e-97 323.1 0.3 3e-49 167.1 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain FXa_inhibition PF14670.1 KFO97930.1 - 1.2e-32 111.7 64.0 1.6e-09 37.7 6.8 4.5 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site VWA_2 PF13519.1 KFO97930.1 - 1.2e-28 100.3 0.0 2.3e-13 50.6 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain cEGF PF12662.2 KFO97930.1 - 8.4e-23 79.6 33.0 3.9e-07 29.5 1.7 5.0 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.10 KFO97930.1 - 3.1e-19 68.6 51.2 4.1e-08 33.0 3.8 4.4 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF PF00008.22 KFO97930.1 - 9.4e-10 38.2 53.9 0.0015 18.4 4.9 5.0 5 0 0 5 5 5 4 EGF-like domain vWA-TerF-like PF10138.4 KFO97930.1 - 3e-09 36.9 0.6 0.00034 20.4 0.0 2.2 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA_3 PF13768.1 KFO97930.1 - 8.1e-08 32.1 0.1 0.0073 16.0 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Matrilin_ccoil PF10393.4 KFO97930.1 - 1.2e-05 24.5 2.1 3.9e-05 22.9 0.5 2.3 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin EGF_3 PF12947.2 KFO97930.1 - 0.0088 15.9 55.3 0.08 12.9 6.4 4.7 4 0 0 4 4 4 2 EGF domain ClpB_D2-small PF10431.4 KFO97930.1 - 0.017 15.0 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein EGF_MSP1_1 PF12946.2 KFO97930.1 - 0.024 14.4 1.4 0.024 14.4 1.0 4.4 4 0 0 4 4 4 0 MSP1 EGF domain 1 BTD PF09270.5 KFO97931.1 - 1.7e-62 209.8 0.0 3.5e-62 208.8 0.0 1.5 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 KFO97931.1 - 7.6e-44 149.5 0.2 2e-43 148.1 0.1 1.7 1 1 0 1 1 1 1 LAG1, DNA binding TIG PF01833.19 KFO97931.1 - 1.4e-06 28.2 0.0 4.1e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Syndecan PF01034.15 KFO97932.1 - 4.3e-24 83.9 0.1 6.8e-24 83.3 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Herpes_gE PF02480.11 KFO97932.1 - 0.074 11.3 0.0 0.091 11.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 KFO97932.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protocadherin SYS1 PF09801.4 KFO97933.1 - 1.6e-37 128.7 5.6 1.7e-37 128.6 3.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Tweety PF04906.8 KFO97933.1 - 0.24 9.7 2.8 0.1 10.9 0.5 1.4 1 1 0 1 1 1 0 Tweety Oxidored_q2 PF00420.19 KFO97933.1 - 1.6 8.4 5.0 6.3 6.4 3.4 1.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Dysbindin PF04440.11 KFO97934.1 - 3.7e-39 133.7 7.1 4.6e-39 133.4 4.9 1.2 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) Gpi16 PF04113.9 KFO97935.1 - 5.1e-131 437.4 0.4 3.1e-129 431.5 0.3 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FDC-SP PF15215.1 KFO97935.1 - 0.044 14.0 0.9 0.34 11.2 0.0 2.7 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide BC10 PF06726.7 KFO97936.1 - 4.4e-27 93.8 10.2 5.7e-27 93.5 7.1 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Pkinase_Tyr PF07714.12 KFO97937.1 - 7e-94 313.7 0.0 9e-94 313.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO97937.1 - 6.2e-51 173.0 0.0 1e-50 172.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFO97937.1 - 1.6e-28 98.2 0.1 3.7e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 KFO97937.1 - 1.4e-05 24.5 0.3 5.3e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFO97937.1 - 0.00015 21.1 0.2 0.0014 17.9 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFO97937.1 - 0.0036 16.7 0.1 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.18 KFO97937.1 - 0.0069 16.1 0.0 0.13 11.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family UPF0239 PF06783.6 KFO97938.1 - 3.6e-23 81.2 0.0 3.9e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0239) DUF4017 PF13209.1 KFO97938.1 - 0.017 14.9 0.2 0.019 14.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4017) Hormone_2 PF00123.15 KFO97939.1 - 1.9e-13 49.9 0.1 6.5e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 Peptide hormone Ribophorin_II PF05817.9 KFO97940.1 - 2.3e-282 937.9 7.7 2.6e-282 937.7 5.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II EMI PF07546.8 KFO97941.1 - 1.4e-19 70.2 5.4 1.4e-19 70.2 3.7 2.0 2 0 0 2 2 1 1 EMI domain Reo_sigmaC PF04582.7 KFO97941.1 - 1.1e-06 28.0 22.0 0.036 13.2 0.3 5.0 2 1 2 5 5 5 3 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KFO97941.1 - 4e-06 26.6 15.4 0.92 9.3 1.3 7.1 3 2 4 7 7 7 1 Baculovirus polyhedron envelope protein, PEP, C terminus TMCO5 PF14992.1 KFO97941.1 - 0.00015 20.9 17.4 0.00087 18.5 5.0 2.8 2 1 0 2 2 2 2 TMCO5 family DUF1664 PF07889.7 KFO97941.1 - 0.00023 20.9 20.1 0.013 15.3 0.7 6.3 3 2 2 6 6 6 2 Protein of unknown function (DUF1664) IncA PF04156.9 KFO97941.1 - 0.0013 18.3 23.1 1.1 8.8 1.7 5.9 2 1 3 5 5 5 1 IncA protein NPV_P10 PF05531.7 KFO97941.1 - 0.0023 18.1 19.0 7.9 6.8 0.3 8.4 6 1 4 10 10 10 0 Nucleopolyhedrovirus P10 protein CorA PF01544.13 KFO97941.1 - 0.0026 16.8 13.0 0.0031 16.5 2.5 3.7 3 1 1 4 4 4 2 CorA-like Mg2+ transporter protein Myosin_tail_1 PF01576.14 KFO97941.1 - 0.0036 15.0 26.3 0.0024 15.6 6.6 2.8 3 1 0 3 3 3 2 Myosin tail Bacillus_HBL PF05791.6 KFO97941.1 - 0.014 14.8 14.1 0.08 12.3 0.5 5.0 4 1 0 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) COG2 PF06148.6 KFO97941.1 - 0.014 15.2 18.3 0.25 11.2 0.6 6.2 4 3 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 KFO97941.1 - 0.025 13.2 26.4 0.11 11.1 0.0 4.8 3 2 4 7 7 7 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KFO97941.1 - 0.051 13.7 29.2 0.81 9.8 2.1 6.8 5 2 3 8 8 7 0 Fibrinogen alpha/beta chain family WXG100 PF06013.7 KFO97941.1 - 0.061 13.3 3.3 13 5.9 0.0 5.9 5 3 1 6 6 6 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.7 KFO97941.1 - 0.094 12.4 29.8 0.11 12.1 0.2 6.5 6 2 1 7 7 6 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 KFO97941.1 - 0.1 12.3 6.5 0.34 10.6 0.1 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper AF0941-like PF14591.1 KFO97941.1 - 0.22 11.6 7.3 0.87 9.6 0.1 4.0 3 2 0 3 3 3 0 AF0941-like WEMBL PF05701.6 KFO97941.1 - 0.41 9.0 14.4 0.66 8.3 0.0 3.5 3 1 1 4 4 4 0 Weak chloroplast movement under blue light FlaC_arch PF05377.6 KFO97941.1 - 1.2 9.0 20.6 13 5.8 0.0 8.5 8 2 3 11 11 10 0 Flagella accessory protein C (FlaC) DUF641 PF04859.7 KFO97941.1 - 2.5 7.8 6.2 6.1 6.6 0.4 3.8 3 2 0 3 3 3 0 Plant protein of unknown function (DUF641) HCMV_UL139 PF12507.3 KFO97941.1 - 3.9 7.6 9.5 4.6 7.4 0.0 4.2 3 2 1 5 5 5 0 Human Cytomegalovirus UL139 protein DivIVA PF05103.8 KFO97941.1 - 5.6 7.0 15.5 2 8.4 0.5 5.1 4 1 1 5 5 5 0 DivIVA protein DUF3573 PF12097.3 KFO97941.1 - 9.4 4.7 8.8 1.6 7.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3573) Homeobox PF00046.24 KFO97942.1 - 3e-35 119.6 14.9 2.6e-08 33.3 0.2 5.4 5 0 0 5 5 5 5 Homeobox domain Homez PF11569.3 KFO97942.1 - 2.4e-22 77.7 4.9 1e-12 46.8 0.1 5.1 5 0 0 5 5 5 4 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFO97942.1 - 7.4e-21 73.5 2.2 0.00044 19.8 0.1 5.5 5 0 0 5 5 5 5 Homeobox KN domain NUFIP1 PF10453.4 KFO97942.1 - 7.5 6.1 13.7 11 5.6 0.0 3.5 3 0 0 3 3 3 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) PI-PLC-X PF00388.14 KFO97943.1 - 8.2e-66 219.9 0.0 1.8e-65 218.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.19 KFO97943.1 - 2.9e-47 158.3 0.1 2e-24 85.1 0.0 3.0 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.14 KFO97943.1 - 4e-42 142.9 0.1 8.5e-42 141.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 PF00018.23 KFO97943.1 - 6.3e-16 57.5 0.6 1.6e-15 56.1 0.4 1.8 1 0 0 1 1 1 1 SH3 domain C2 PF00168.25 KFO97943.1 - 2.6e-15 56.0 0.0 8.3e-15 54.4 0.0 2.0 1 0 0 1 1 1 1 C2 domain PH PF00169.24 KFO97943.1 - 9.7e-13 48.2 0.3 0.00057 20.0 0.1 4.1 4 0 0 4 4 4 3 PH domain SH3_9 PF14604.1 KFO97943.1 - 1e-12 47.3 0.9 1.5e-11 43.7 0.2 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFO97943.1 - 5.5e-09 35.3 0.1 1.1e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_like PF09279.6 KFO97943.1 - 1.4e-06 28.2 0.8 4.1e-06 26.7 0.6 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 KFO97943.1 - 8.4e-05 22.1 0.0 0.00034 20.2 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_6 PF13405.1 KFO97943.1 - 0.033 14.0 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KFO97943.1 - 0.046 13.8 3.8 0.061 13.4 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair Topoisom_I_N PF02919.10 KFO97944.1 - 5e-103 342.9 8.2 5e-103 342.9 5.7 5.1 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KFO97944.1 - 3.2e-97 324.2 4.6 3.2e-97 324.2 3.2 3.3 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KFO97944.1 - 3.6e-34 116.2 0.5 4.6e-33 112.6 0.3 3.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Hanta_nucleocap PF00846.13 KFO97944.1 - 0.00038 19.2 7.0 0.00073 18.3 4.9 1.4 1 0 0 1 1 1 1 Hantavirus nucleocapsid protein C2 PF00168.25 KFO97945.1 - 1.1e-12 47.6 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain Ion_trans_2 PF07885.11 KFO97946.1 - 3.7e-35 119.4 16.9 3.1e-19 68.4 1.0 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 KFO97946.1 - 0.0069 15.6 15.2 0.097 11.9 0.8 2.5 1 1 1 2 2 2 2 Ion transport protein IRK PF01007.15 KFO97946.1 - 1.3 7.7 3.8 0.61 8.8 0.1 1.9 2 0 0 2 2 2 0 Inward rectifier potassium channel DUF2101 PF09874.4 KFO97946.1 - 4 6.8 6.9 27 4.1 0.0 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) IGFBP PF00219.13 KFO97947.1 - 3.8e-13 49.7 21.6 3.8e-13 49.7 15.0 2.6 2 1 0 2 2 2 1 Insulin-like growth factor binding protein VWC PF00093.13 KFO97947.1 - 1.2e-05 25.2 2.4 1.2e-05 25.2 1.7 3.1 3 0 0 3 3 3 1 von Willebrand factor type C domain PMR5N PF14416.1 KFO97947.1 - 0.073 13.1 0.2 0.073 13.1 0.2 2.8 2 1 1 3 3 3 0 PMR5 N terminal Domain A_deaminase PF00962.17 KFO97948.1 - 1.7e-89 299.9 0.0 1.9e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase PKI PF02827.11 KFO97949.1 - 1.6e-17 63.3 0.2 1.7e-17 63.2 0.2 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor AAR2 PF05282.6 KFO97950.1 - 4.9e-53 180.3 0.0 6.4e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Alginate_lyase PF05426.7 KFO97950.1 - 0.0076 15.6 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Alginate lyase 4_1_CTD PF05902.8 KFO97951.1 - 7.6e-42 141.9 3.1 7.6e-42 141.9 2.1 2.9 3 1 1 4 4 4 1 4.1 protein C-terminal domain (CTD) FERM_C PF09380.5 KFO97951.1 - 1.9e-23 82.4 0.0 3.4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFO97951.1 - 1.4e-22 79.5 0.1 1e-21 76.7 0.0 2.4 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 KFO97951.1 - 3.4e-21 75.7 0.7 9.2e-21 74.3 0.0 2.1 2 0 0 2 2 2 1 FERM central domain FA PF08736.6 KFO97951.1 - 8.9e-19 67.0 4.3 3e-18 65.3 3.0 2.0 1 0 0 1 1 1 1 FERM adjacent (FA) SAB PF04382.8 KFO97951.1 - 1e-18 66.7 1.8 1e-18 66.7 1.2 2.2 2 0 0 2 2 2 1 SAB domain RRM_1 PF00076.17 KFO97952.1 - 3.1e-14 52.3 0.0 4.9e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO97952.1 - 2.8e-10 40.0 0.0 4.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO97952.1 - 3.1e-05 23.7 0.0 8.7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 KFO97952.1 - 0.0031 17.3 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.14 KFO97953.1 - 9.9e-11 41.7 0.0 2.1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO97953.1 - 4.9e-09 36.4 0.1 9.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 KFO97953.1 - 0.056 13.6 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 YABBY protein Mitofilin PF09731.4 KFO97953.1 - 0.28 9.7 6.0 0.35 9.4 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Glyco_hydro_47 PF01532.15 KFO97954.1 - 6.6e-146 486.5 0.0 7.8e-146 486.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3689 PF12463.3 KFO97955.1 - 6e-133 442.2 13.5 9.2e-133 441.6 9.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) Myosin_tail_1 PF01576.14 KFO97956.1 - 0 1060.6 262.0 0 1044.3 134.6 3.1 1 1 0 2 2 2 2 Myosin tail Myosin_head PF00063.16 KFO97956.1 - 2.9e-272 904.7 0.4 2.9e-272 904.7 0.3 3.3 3 0 0 3 3 1 1 Myosin head (motor domain) Myosin_N PF02736.14 KFO97956.1 - 2.2e-14 52.8 8.0 5.3e-14 51.6 5.5 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 KFO97956.1 - 3.4e-12 46.4 215.7 3.2e-06 26.8 28.2 9.9 1 1 7 8 8 8 5 Intermediate filament protein Reo_sigmaC PF04582.7 KFO97956.1 - 1.6e-06 27.5 74.2 0.0027 16.9 2.2 9.9 1 1 9 12 12 12 8 Reovirus sigma C capsid protein DUF869 PF05911.6 KFO97956.1 - 3.4e-05 22.3 8.2 3.4e-05 22.3 5.7 7.5 1 1 5 6 6 5 2 Plant protein of unknown function (DUF869) IncA PF04156.9 KFO97956.1 - 0.0013 18.4 251.6 0.0019 17.8 9.7 12.1 1 1 11 12 12 12 6 IncA protein CENP-F_leu_zip PF10473.4 KFO97956.1 - 0.0049 16.7 20.6 0.0049 16.7 14.3 11.6 2 2 8 10 10 10 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 KFO97956.1 - 0.0056 16.4 3.4 0.0056 16.4 2.3 12.0 3 1 8 12 12 12 4 Protein of unknown function (DUF1664) IQ PF00612.22 KFO97956.1 - 0.0056 16.2 1.3 0.069 12.8 0.2 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_13 PF13166.1 KFO97956.1 - 0.0092 14.4 188.1 0.022 13.2 22.6 7.6 1 1 6 7 7 7 3 AAA domain AAA_22 PF13401.1 KFO97956.1 - 0.093 12.8 0.0 0.093 12.8 0.0 6.0 4 3 0 5 5 5 0 AAA domain DUF1072 PF06380.6 KFO97957.1 - 0.051 13.2 2.4 0.086 12.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) GSH_synth_ATP PF03917.12 KFO97959.1 - 2.9e-136 453.9 0.0 3.2e-136 453.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KFO97959.1 - 1.6e-29 102.0 0.3 3.5e-29 100.9 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase AMP-binding PF00501.23 KFO97960.1 - 5.5e-92 308.3 0.0 6.5e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO97960.1 - 7.2e-21 74.9 0.0 1.3e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Y_phosphatase PF00102.22 KFO97961.1 - 9.3e-153 506.2 1.4 5.8e-85 284.3 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFO97961.1 - 6.8e-29 99.8 2.1 4.5e-11 42.7 0.0 5.7 4 1 1 5 5 5 3 Fibronectin type III domain MAM PF00629.18 KFO97961.1 - 3.7e-28 98.3 0.0 8.1e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 MAM domain DSPc PF00782.15 KFO97961.1 - 3.3e-09 36.4 0.1 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFO97961.1 - 1.4e-05 25.3 0.1 0.016 15.4 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFO97961.1 - 6.9e-05 22.9 0.0 0.44 10.5 0.0 2.6 2 0 0 2 2 2 2 Inositol hexakisphosphate Ig_2 PF13895.1 KFO97961.1 - 0.001 19.1 0.1 0.0035 17.4 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFO97961.1 - 0.036 13.9 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain DctM PF06808.7 KFO97961.1 - 0.2 10.1 0.1 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 DctM-like transporters Yae1_N PF09811.4 KFO97962.1 - 8.7e-19 66.7 62.0 0.12 11.9 1.3 5.8 1 1 1 2 2 2 1 Essential protein Yae1, N terminal HECT PF00632.20 KFO97963.1 - 2.6e-96 322.5 0.3 3.5e-96 322.0 0.2 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFO97963.1 - 1.4e-43 146.2 20.5 7.3e-13 48.1 0.6 4.6 4 0 0 4 4 4 4 WW domain C2 PF00168.25 KFO97963.1 - 2.5e-12 46.4 0.4 5.5e-12 45.3 0.3 1.6 1 0 0 1 1 1 1 C2 domain DUF605 PF04652.11 KFO97963.1 - 0.001 18.5 16.5 0.0016 17.9 11.4 1.2 1 0 0 1 1 1 1 Vta1 like CDC27 PF09507.5 KFO97963.1 - 0.24 10.5 4.1 0.37 9.9 2.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Robl_LC7 PF03259.12 KFO97964.1 - 5.3e-26 90.0 0.0 5.8e-26 89.8 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Atg8 PF02991.11 KFO97965.1 - 2.4e-45 152.7 0.4 2.7e-45 152.5 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFO97965.1 - 2.1e-06 27.8 0.0 2.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Telomere_Sde2 PF13019.1 KFO97965.1 - 0.076 12.6 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 Telomere stability and silencing Peptidase_M10 PF00413.19 KFO97966.1 - 7.2e-60 201.1 0.2 1.3e-59 200.3 0.2 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFO97966.1 - 4.4e-54 179.9 20.2 7.5e-16 57.5 0.6 4.6 4 0 0 4 4 4 4 Hemopexin DUF3377 PF11857.3 KFO97966.1 - 2e-32 110.6 2.2 3.5e-32 109.8 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PG_binding_1 PF01471.13 KFO97966.1 - 3.2e-11 43.0 0.1 6.7e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFO97966.1 - 0.00017 21.0 0.8 0.45 9.8 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4293 PF14126.1 KFO97966.1 - 0.0068 16.3 0.1 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) Metallopep PF12044.3 KFO97966.1 - 0.057 11.8 0.1 0.09 11.2 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M54 PF07998.6 KFO97966.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_3 PF13582.1 KFO97966.1 - 0.1 13.1 0.7 0.21 12.1 0.5 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFO97966.1 - 0.23 11.4 1.0 0.4 10.7 0.7 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFO97966.1 - 0.26 10.7 0.2 0.45 10.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like eIF-6 PF01912.13 KFO97967.1 - 9e-61 204.4 0.4 2.7e-60 202.8 0.1 1.7 2 0 0 2 2 2 1 eIF-6 family DUF1669 PF07894.7 KFO97968.1 - 1.4e-97 326.3 0.0 2.7e-97 325.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFO97968.1 - 0.0033 17.1 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain Cytadhesin_P30 PF07271.6 KFO97968.1 - 0.11 11.7 2.4 0.18 11.0 1.6 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Ubiq_cyt_C_chap PF03981.7 KFO97969.1 - 3.2e-43 146.9 0.1 4.7e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TGF_beta PF00019.15 KFO97970.1 - 5e-38 129.5 0.6 8.8e-38 128.8 0.4 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFO97970.1 - 2e-19 69.8 0.0 4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 TGF-beta propeptide Rootletin PF15035.1 KFO97971.1 - 1.8e-36 125.8 11.5 1.8e-36 125.8 8.0 19.2 4 3 14 18 18 18 1 Ciliary rootlet component, centrosome cohesion HTH_36 PF13730.1 KFO97971.1 - 0.13 12.4 1.2 30 4.8 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain COPIIcoated_ERV PF07970.7 KFO97972.1 - 2.7e-84 282.2 0.8 3.4e-84 281.9 0.6 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFO97972.1 - 3.4e-15 55.7 0.0 7.8e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Glyco_transf_29 PF00777.13 KFO97973.1 - 3.7e-78 262.3 0.0 4.1e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF2628 PF10947.3 KFO97974.1 - 0.047 13.4 2.2 0.044 13.5 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) MRAP PF15183.1 KFO97974.1 - 0.096 12.2 2.3 0.1 12.1 1.6 1.2 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Wzy_C PF04932.10 KFO97974.1 - 0.29 10.9 3.5 0.33 10.7 2.4 1.1 1 0 0 1 1 1 0 O-Antigen ligase Synaptobrevin PF00957.16 KFO97974.1 - 2.8 7.6 4.8 3.3 7.3 3.3 1.1 1 0 0 1 1 1 0 Synaptobrevin C2 PF00168.25 KFO97976.1 - 1.2e-19 69.8 0.4 1.6e-19 69.4 0.0 1.4 2 0 0 2 2 2 1 C2 domain Copine PF07002.11 KFO97977.1 - 9.4e-61 203.8 0.0 1.8e-60 202.9 0.0 1.5 1 0 0 1 1 1 1 Copine C2 PF00168.25 KFO97977.1 - 1.3e-21 76.2 0.0 1.9e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFO97977.1 - 4e-10 39.8 0.0 6.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 KFO97977.1 - 0.032 13.9 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain TLV_coat PF00429.14 KFO97978.1 - 0.0034 15.9 0.3 0.0038 15.7 0.2 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) Aminotran_5 PF00266.14 KFO97979.1 - 2.4e-92 309.5 0.0 2.7e-92 309.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFO97979.1 - 2.4e-12 46.5 0.0 3.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFO97979.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 KFO97979.1 - 0.005 16.7 0.1 0.55 10.1 0.0 2.7 3 0 0 3 3 3 1 B12 binding domain Pyridoxal_deC PF00282.14 KFO97979.1 - 0.031 12.7 0.0 0.05 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Romo1 PF10247.4 KFO97980.1 - 1.7e-27 95.3 18.9 2e-27 95.1 13.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 KFO97980.1 - 0.034 14.1 9.7 0.041 13.9 6.7 1.1 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.17 KFO97981.1 - 3.2e-31 106.7 0.0 1.1e-24 85.8 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KFO97981.1 - 1.4e-23 82.9 1.3 1.9e-22 79.2 0.9 2.5 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_6 PF14259.1 KFO97981.1 - 3.3e-22 78.2 0.2 4.6e-16 58.5 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO97981.1 - 1.2e-19 69.9 0.2 2.2e-11 43.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 KFO97981.1 - 0.078 11.4 23.5 0.13 10.7 16.3 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3776 PF12618.3 KFO97982.1 - 6.2e-13 49.2 15.4 6.2e-13 49.2 10.7 4.8 4 1 1 5 5 5 1 Protein of unknown function (DUF3776) PHD PF00628.24 KFO97982.1 - 1.1e-06 28.2 12.6 4.8e-06 26.1 8.8 2.2 1 0 0 1 1 1 1 PHD-finger DUF4537 PF15057.1 KFO97982.1 - 0.00059 19.6 0.0 0.0023 17.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor-knot PF11717.3 KFO97982.1 - 0.0016 18.0 2.8 0.0058 16.3 0.9 2.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Rad9_Rad53_bind PF08605.5 KFO97982.1 - 0.0017 18.1 0.2 0.14 11.9 0.1 2.8 2 0 0 2 2 2 1 Fungal Rad9-like Rad53-binding zf-C2H2 PF00096.21 KFO97982.1 - 3.3 8.2 11.3 0.58 10.6 4.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type SH2 PF00017.19 KFO97983.1 - 2.5e-22 78.4 0.1 3.5e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 KFO97983.1 - 0.00085 18.8 0.0 0.012 15.2 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFO97983.1 - 0.034 13.5 0.0 0.082 12.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain Ndr PF03096.9 KFO97984.1 - 3.7e-125 416.0 0.0 4.4e-125 415.8 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 KFO97984.1 - 2.1e-15 57.2 0.0 3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO97984.1 - 1.4e-05 24.7 0.0 5e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Rap_GAP PF02145.10 KFO97985.1 - 0.0013 18.1 0.0 1.5 8.1 0.0 2.9 3 0 0 3 3 3 2 Rap/ran-GAP SNF2_N PF00176.18 KFO97986.1 - 2.1e-68 230.3 1.6 3.1e-68 229.7 1.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KFO97986.1 - 3.6e-25 87.3 3.8 4.3e-13 48.7 0.7 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFO97986.1 - 7.8e-13 48.1 0.0 2.3e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRK PF07533.11 KFO97986.1 - 7.4e-09 34.9 0.2 7.2e-08 31.7 0.0 2.3 2 0 0 2 2 2 1 BRK domain ResIII PF04851.10 KFO97986.1 - 1.4e-06 28.2 0.1 7.4e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFO97986.1 - 6.8e-05 22.4 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.6 KFO97986.1 - 0.008 15.9 1.5 17 5.1 0.0 3.6 3 0 0 3 3 3 2 CHDCT2 (NUC038) domain RB_A PF01858.12 KFO97987.1 - 5.3e-81 270.9 0.5 5.3e-81 270.9 0.3 2.5 3 0 0 3 3 3 1 Retinoblastoma-associated protein A domain RB_B PF01857.15 KFO97987.1 - 7.9e-59 197.0 0.2 2.2e-58 195.5 0.1 1.8 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.3 KFO97987.1 - 2.9e-36 123.8 1.7 9.1e-36 122.2 1.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) Rb_C PF08934.5 KFO97987.1 - 1.2e-05 24.9 0.5 2.6e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 Rb C-terminal domain Phage_F PF02305.12 KFO97987.1 - 0.029 12.9 0.1 0.045 12.3 0.1 1.2 1 0 0 1 1 1 0 Capsid protein (F protein) HD PF01966.17 KFO97988.1 - 1.6e-15 57.2 0.0 4.6e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 HD domain TLD PF07534.11 KFO97989.1 - 1.1e-36 125.9 0.0 1.2e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 TLD PIG-U PF06728.8 KFO97990.1 - 3.2e-105 352.1 49.3 3.7e-105 351.9 34.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U RVT_1 PF00078.22 KFO97991.1 - 1.7e-22 79.8 0.0 2.2e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_4 PF13853.1 KFO97992.1 - 4.1e-43 146.6 7.1 4.1e-43 146.6 4.9 2.1 1 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFO97992.1 - 9.1e-17 61.0 6.9 1e-16 60.8 4.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Reticulon PF02453.12 KFO97992.1 - 0.0012 18.5 0.5 0.0012 18.5 0.3 2.4 3 0 0 3 3 3 1 Reticulon TMEM18 PF14770.1 KFO97992.1 - 0.0042 16.5 0.9 0.0079 15.7 0.1 1.9 2 0 0 2 2 2 1 Transmembrane protein 18 DUF4519 PF15012.1 KFO97992.1 - 0.013 15.4 1.4 7.1 6.6 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Patched PF02460.13 KFO97993.1 - 1.4e-97 327.5 21.4 2.5e-97 326.7 14.8 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KFO97993.1 - 1.8e-24 85.9 2.4 1.8e-24 85.9 1.7 2.5 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation AhpC-TSA PF00578.16 KFO97994.1 - 2.8e-35 120.6 0.0 3.6e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFO97994.1 - 1.1e-12 47.7 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFO97994.1 - 1.5e-10 40.5 0.7 2.6e-10 39.7 0.1 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin 4HBT PF03061.17 KFO97995.1 - 1.1e-10 41.4 0.0 0.0001 22.3 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Acetyltransf_1 PF00583.19 KFO97996.1 - 4.4e-16 58.6 0.0 6.6e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFO97996.1 - 2.8e-08 33.7 0.2 7.4e-08 32.4 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFO97996.1 - 6.4e-06 26.2 0.0 8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFO97996.1 - 0.00016 21.6 0.1 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFO97996.1 - 0.0003 20.9 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFO97996.1 - 0.00075 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein ApoO PF09769.4 KFO97997.1 - 3.5e-28 98.3 0.0 3.9e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein O Kelch_1 PF01344.20 KFO97998.1 - 8.4e-47 156.4 8.9 1.4e-12 46.9 0.0 5.7 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 KFO97998.1 - 1.5e-36 123.0 2.7 2.5e-10 40.0 0.0 5.7 3 2 2 5 5 5 5 Kelch motif BTB PF00651.26 KFO97998.1 - 4.4e-24 84.6 1.8 4.4e-24 84.6 1.2 2.2 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFO97998.1 - 5e-22 77.4 3.6 0.00064 19.4 0.0 6.2 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KFO97998.1 - 1.3e-19 69.7 0.4 6.4e-06 26.1 0.0 5.7 5 1 0 5 5 5 4 Galactose oxidase, central domain BACK PF07707.10 KFO97998.1 - 9.5e-17 60.7 0.6 2e-16 59.6 0.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFO97998.1 - 2e-14 52.7 11.4 0.00097 18.8 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KFO97998.1 - 2e-08 33.9 6.6 1.3 9.0 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Rax2 PF12768.2 KFO97998.1 - 0.0003 20.1 0.0 0.011 15.0 0.0 2.7 3 0 0 3 3 3 1 Cortical protein marker for cell polarity GTP_EFTU PF00009.22 KFO97999.1 - 8.3e-40 136.2 0.1 1.3e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KFO97999.1 - 1.2e-37 127.7 0.3 3e-37 126.5 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KFO97999.1 - 9.4e-13 48.0 0.3 2.7e-12 46.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFO97999.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFO97999.1 - 0.079 12.7 0.2 0.54 10.0 0.1 2.1 1 1 0 2 2 2 0 Dynamin family Zfx_Zfy_act PF04704.8 KFO98000.1 - 6.9e-163 541.2 23.0 6.9e-163 541.2 15.9 1.5 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-H2C2_2 PF13465.1 KFO98000.1 - 1e-46 154.9 117.3 2.8e-08 33.6 0.8 13.5 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFO98000.1 - 4.5e-39 130.4 116.7 1.4e-05 25.1 1.3 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO98000.1 - 1.4e-29 100.2 99.0 0.00053 20.1 1.5 13.4 13 0 0 13 13 13 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO98000.1 - 6.8e-17 61.0 71.9 0.0011 18.9 0.0 12.2 12 0 0 12 12 12 7 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFO98000.1 - 7.4e-16 57.3 94.2 0.00044 20.3 1.0 12.3 12 0 0 12 12 12 8 C2H2-type zinc-finger domain ROS_MUCR PF05443.6 KFO98000.1 - 0.013 15.3 0.1 0.013 15.3 0.1 3.4 4 0 0 4 4 4 0 ROS/MUCR transcriptional regulator protein Adhes-Ig_like PF09085.5 KFO98000.1 - 0.14 11.9 1.2 0.37 10.6 0.8 1.7 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like zf-met PF12874.2 KFO98000.1 - 0.26 11.5 0.0 0.26 11.5 0.0 11.5 12 1 0 12 12 12 0 Zinc-finger of C2H2 type Solute_trans_a PF03619.11 KFO98001.1 - 9.8e-25 87.3 16.2 1.2e-24 87.0 11.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha AmiS_UreI PF02293.10 KFO98001.1 - 0.021 14.4 2.4 0.021 14.4 1.6 2.0 2 0 0 2 2 2 0 AmiS/UreI family transporter DUF2427 PF10348.4 KFO98001.1 - 0.92 9.1 11.4 1.2 8.7 0.4 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF2427) BCDHK_Adom3 PF10436.4 KFO98002.1 - 2.2e-58 196.3 0.0 3.4e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFO98002.1 - 3.7e-19 68.4 0.0 5.6e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFO98002.1 - 0.0075 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CTP_transf_2 PF01467.21 KFO98003.1 - 3.5e-23 82.3 0.0 6.2e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase GldM_N PF12081.3 KFO98003.1 - 0.018 14.5 1.5 0.028 13.9 1.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Lipoprotein_6 PF01441.14 KFO98003.1 - 0.03 14.1 2.7 0.051 13.4 1.9 1.3 1 0 0 1 1 1 0 Lipoprotein UPF0158 PF03682.8 KFO98003.1 - 0.21 11.2 6.6 2.5 7.6 4.4 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0158) DNA_pol_B PF00136.16 KFO98004.1 - 9.2e-123 410.4 0.1 1.4e-122 409.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KFO98004.1 - 1.6e-56 190.6 7.0 2.9e-56 189.8 4.9 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KFO98004.1 - 1.2e-54 185.4 0.0 2.5e-54 184.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KFO98004.1 - 7e-16 57.8 13.0 7e-16 57.8 9.0 2.7 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.7 KFO98004.1 - 0.017 13.6 0.6 0.055 12.0 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1744) I-set PF07679.11 KFO98005.1 - 7.9e-06 25.6 0.0 9.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO98005.1 - 3.2e-05 23.9 0.0 3.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO98005.1 - 0.00062 19.6 0.4 0.0012 18.7 0.3 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFO98005.1 - 0.0047 17.0 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO98005.1 - 0.0056 17.1 0.1 0.015 15.8 0.1 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Sp38 PF07354.7 KFO98005.1 - 0.048 12.3 0.0 0.048 12.3 0.0 1.0 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) V-set_CD47 PF08204.6 KFO98005.1 - 0.076 12.7 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Frizzled PF01534.12 KFO98006.1 - 2.1e-136 454.0 16.9 2.8e-136 453.6 11.7 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFO98006.1 - 1.8e-30 105.7 7.5 3.6e-30 104.7 5.2 1.5 1 0 0 1 1 1 1 Fz domain Glyco_transf_64 PF09258.5 KFO98007.1 - 1.6e-97 325.5 0.1 2.8e-97 324.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 KFO98007.1 - 7.5e-53 179.5 0.0 1.1e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Exostosin family ADIP PF11559.3 KFO98007.1 - 0.01 15.7 8.1 0.017 15.0 5.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 KFO98007.1 - 0.058 13.4 5.5 0.12 12.4 3.8 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 KFO98007.1 - 0.061 13.1 2.6 0.12 12.1 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 KFO98007.1 - 0.21 12.0 0.4 0.48 10.8 0.3 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.6 KFO98007.1 - 0.24 10.0 5.1 0.44 9.1 3.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Noelin-1 PF12308.3 KFO98007.1 - 0.41 10.4 1.8 1 9.1 1.3 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein Cortex-I_coil PF09304.5 KFO98007.1 - 1.7 8.7 9.6 0.47 10.5 4.4 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil TPR_MLP1_2 PF07926.7 KFO98007.1 - 5.4 6.7 12.8 0.68 9.6 6.1 1.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Beta-Casp PF10996.3 KFO98008.1 - 2.2e-11 43.8 0.0 3.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain HNF-1_N PF04814.8 KFO98009.1 - 1.4e-11 44.8 6.3 2.2e-11 44.1 1.3 2.7 2 1 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.24 KFO98009.1 - 1.1e-10 41.0 3.6 1.3e-10 40.7 0.4 2.7 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.6 KFO98009.1 - 0.00011 21.7 1.6 0.0029 17.2 0.0 3.0 3 1 0 3 3 3 1 Homeobox KN domain HTH_37 PF13744.1 KFO98009.1 - 0.00072 19.3 0.5 0.00072 19.3 0.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.17 KFO98009.1 - 0.0025 17.6 0.1 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KFO98009.1 - 0.0036 17.3 0.3 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain CUT PF02376.10 KFO98009.1 - 0.011 15.4 0.1 0.035 13.9 0.1 1.8 1 0 0 1 1 1 0 CUT domain HTH_24 PF13412.1 KFO98009.1 - 0.038 13.3 0.0 0.16 11.3 0.0 2.1 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.1 KFO98009.1 - 0.057 13.6 2.1 0.11 12.7 0.1 2.4 3 0 0 3 3 2 0 Helix-turn-helix domain DUF494 PF04361.8 KFO98009.1 - 0.084 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) HTH_26 PF13443.1 KFO98009.1 - 0.12 12.5 0.0 0.38 10.9 0.0 2.0 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.1 KFO98009.1 - 0.26 11.0 0.1 0.26 11.0 0.1 2.6 3 0 0 3 3 2 0 Homeodomain-like domain Pex14_N PF04695.8 KFO98009.1 - 0.36 10.8 5.9 0.19 11.7 1.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_pol_viral_N PF00242.12 KFO98011.1 - 9.1 5.1 13.3 10 5.0 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ras PF00071.17 KFO98012.1 - 1.3e-59 200.2 0.2 1.4e-59 200.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98012.1 - 4.7e-22 78.7 0.0 6.6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO98012.1 - 2.1e-14 53.1 0.0 2.6e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO98012.1 - 9.1e-07 28.4 0.0 1.7e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFO98012.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFO98012.1 - 6.2e-05 22.2 0.0 7.5e-05 21.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFO98012.1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFO98012.1 - 0.0028 17.7 0.1 0.0097 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KFO98012.1 - 0.0031 16.9 0.1 0.013 15.0 0.0 1.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFO98012.1 - 0.01 15.7 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 KFO98012.1 - 0.011 15.2 0.0 2.3 7.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein KaiC PF06745.8 KFO98012.1 - 0.023 13.8 0.1 0.046 12.8 0.1 1.5 1 0 0 1 1 1 0 KaiC Septin PF00735.13 KFO98012.1 - 0.052 12.5 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Septin NACHT PF05729.7 KFO98012.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KFO98012.1 - 0.066 13.1 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFO98012.1 - 0.068 12.8 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 KFO98012.1 - 0.071 12.0 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 KFO98012.1 - 0.077 13.1 0.2 0.55 10.4 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KFO98012.1 - 0.098 11.6 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ras PF00071.17 KFO98013.1 - 7.2e-35 119.7 0.0 8.6e-35 119.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98013.1 - 2.5e-09 37.6 0.0 4.8e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Lipase_GDSL_3 PF14606.1 KFO98013.1 - 0.00054 19.7 0.0 0.00071 19.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GTP_EFTU PF00009.22 KFO98013.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SprT-like PF10263.4 KFO98014.1 - 2.5e-39 134.4 1.2 3.9e-39 133.8 0.8 1.3 1 0 0 1 1 1 1 SprT-like family WLM PF08325.5 KFO98014.1 - 0.35 10.7 7.8 7.5 6.3 5.4 2.3 1 1 0 1 1 1 0 WLM domain 2OG-FeII_Oxy_3 PF13640.1 KFO98015.1 - 4.8e-14 52.6 0.0 5.2e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFO98015.1 - 4.3e-07 29.4 0.1 1.7e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFO98015.1 - 1.3e-05 25.4 0.0 1.4e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Translin PF01997.11 KFO98016.1 - 4.1e-47 160.3 0.0 4.9e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Translin family UVR PF02151.14 KFO98017.1 - 0.0027 17.1 7.9 0.0027 17.1 5.5 3.1 2 0 0 2 2 2 1 UvrB/uvrC motif FlaF PF07309.6 KFO98017.1 - 0.12 12.2 4.8 0.42 10.4 0.0 3.3 2 1 1 3 3 3 0 Flagellar protein FlaF Reo_sigmaC PF04582.7 KFO98017.1 - 0.46 9.5 2.7 0.91 8.6 1.0 2.2 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 KFO98017.1 - 1.3 8.7 12.6 0.64 9.7 0.2 3.9 3 1 1 4 4 4 0 Laminin Domain II Baculo_p24 PF05073.7 KFO98017.1 - 3 7.3 8.2 0.44 10.1 0.3 2.9 2 2 0 2 2 2 0 Baculovirus P24 capsid protein Phlebovirus_NSM PF07246.6 KFO98017.1 - 6.1 5.9 11.2 4 6.5 2.1 3.3 3 0 0 3 3 3 0 Phlebovirus nonstructural protein NS-M DUF3401 PF11881.3 KFO98018.1 - 2.1e-77 259.7 0.3 4.8e-77 258.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3401) Rap_GAP PF02145.10 KFO98018.1 - 1.9e-62 210.0 0.0 5.7e-62 208.4 0.0 1.9 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.19 KFO98018.1 - 1.6e-05 25.0 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) IncA PF04156.9 KFO98018.1 - 0.0077 15.8 3.1 0.017 14.7 2.2 1.5 1 0 0 1 1 1 1 IncA protein DUF2968 PF11180.3 KFO98018.1 - 5.6 6.3 12.0 0.35 10.2 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) AA_permease_2 PF13520.1 KFO98019.1 - 2.1e-53 181.4 42.8 2.6e-53 181.1 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFO98019.1 - 3.5e-25 88.2 39.1 4.3e-25 87.9 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease LRR_4 PF12799.2 KFO98020.1 - 2.4e-18 65.2 19.6 6.9e-09 35.1 3.4 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO98020.1 - 1.2e-10 40.9 24.7 2.8e-07 30.1 5.9 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 KFO98020.1 - 0.00011 21.8 21.8 0.016 15.2 0.1 6.1 3 1 3 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 KFO98020.1 - 0.007 16.2 25.8 0.37 11.0 0.2 5.7 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFO98020.1 - 0.046 13.8 16.2 4 8.0 0.3 5.9 5 0 0 5 5 5 0 Leucine rich repeat Carb_anhydrase PF00194.16 KFO98021.1 - 3.2e-104 347.4 0.0 3.6e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 KFO98022.1 - 1.2e-91 306.2 0.0 1.4e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 KFO98023.1 - 3.1e-94 314.7 0.0 4.1e-94 314.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF3715 PF12509.3 KFO98023.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Carb_anhydrase PF00194.16 KFO98024.1 - 2.4e-120 400.2 0.0 2.7e-120 400.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase vATP-synt_AC39 PF01992.11 KFO98025.1 - 1.2e-106 356.6 0.0 1.4e-106 356.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit HECT PF00632.20 KFO98026.1 - 6.2e-95 317.9 0.5 9.9e-95 317.3 0.4 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFO98026.1 - 1.9e-47 158.6 33.1 4.9e-13 48.6 2.2 4.5 4 0 0 4 4 4 4 WW domain C2 PF00168.25 KFO98026.1 - 1.9e-08 34.0 0.2 4e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 C2 domain TPR_17 PF13431.1 KFO98027.1 - 7.5e-09 35.0 0.2 0.059 13.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFO98027.1 - 1.2e-07 30.9 11.0 0.15 11.7 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFO98027.1 - 6.2e-07 29.9 0.2 0.59 10.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFO98027.1 - 2e-06 27.3 4.4 0.13 11.9 0.0 4.3 2 2 2 4 4 4 3 TPR repeat TPR_19 PF14559.1 KFO98027.1 - 2.6e-05 24.4 1.3 0.13 12.6 0.1 4.3 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFO98027.1 - 6.9e-05 22.4 13.3 0.73 9.8 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO98027.1 - 0.00053 20.4 0.9 24 5.9 0.3 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFO98027.1 - 0.015 15.0 3.4 0.63 9.9 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFO98027.1 - 0.016 15.0 1.8 7.3 6.6 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Copine PF07002.11 KFO98028.1 - 1.1e-61 206.9 0.1 2.1e-61 205.9 0.0 1.5 2 0 0 2 2 2 1 Copine C2 PF00168.25 KFO98028.1 - 8.9e-29 99.1 0.2 3.4e-15 55.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFO98028.1 - 2.5e-09 37.2 0.0 8.7e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.23 KFO98028.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Yos1 PF08571.5 KFO98030.1 - 8.1e-15 54.6 0.1 8.6e-15 54.6 0.1 1.0 1 0 0 1 1 1 1 Yos1-like Hydrolase_6 PF13344.1 KFO98031.1 - 2.4e-16 59.4 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFO98031.1 - 5.1e-15 54.9 0.0 1.4e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KFO98031.1 - 6.2e-06 26.5 0.0 0.00017 21.8 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFO98031.1 - 0.021 15.2 0.2 0.6 10.4 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4032 PF13224.1 KFO98031.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) AAA PF00004.24 KFO98032.1 - 3.6e-37 127.4 0.0 7.2e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFO98032.1 - 3.1e-05 24.0 0.0 0.0023 17.9 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFO98032.1 - 4.3e-05 23.6 0.1 0.00014 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFO98032.1 - 5.7e-05 22.2 0.0 9.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFO98032.1 - 0.00039 21.2 0.0 0.00094 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFO98032.1 - 0.00045 19.0 0.0 0.00074 18.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KFO98032.1 - 0.00053 19.6 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KFO98032.1 - 0.00056 19.6 0.0 0.0012 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KFO98032.1 - 0.0021 17.5 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KFO98032.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KFO98032.1 - 0.0026 17.3 0.0 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFO98032.1 - 0.0056 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFO98032.1 - 0.0061 16.7 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 KFO98032.1 - 0.0068 15.8 0.3 0.098 12.0 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KFO98032.1 - 0.0094 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFO98032.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KFO98032.1 - 0.045 12.6 0.0 0.082 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KFO98032.1 - 0.048 12.8 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 KFO98032.1 - 0.05 12.4 0.1 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KFO98032.1 - 0.053 12.9 0.0 1.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.1 KFO98032.1 - 0.067 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFO98032.1 - 0.1 12.2 0.0 0.66 9.6 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KFO98032.1 - 0.11 12.1 0.0 2.7 7.6 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase PINIT PF14324.1 KFO98033.1 - 1.3e-41 141.9 0.1 2.4e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFO98033.1 - 5.1e-21 73.9 5.3 1.1e-20 72.8 3.7 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFO98033.1 - 0.00026 20.4 1.8 0.00081 18.8 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 KFO98033.1 - 0.14 11.8 2.2 0.3 10.8 1.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 KFO98034.1 - 7.5e-16 57.6 10.3 8.9e-16 57.4 4.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO98034.1 - 3.8e-09 36.0 3.8 3.8e-09 36.0 2.6 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO98034.1 - 2.7e-08 33.6 5.6 2.7e-08 33.6 3.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFO98034.1 - 7.5e-08 32.3 6.3 2.1e-07 30.9 4.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFO98034.1 - 1.2e-07 31.2 8.4 1.9e-07 30.7 2.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFO98034.1 - 1.4e-07 30.9 4.8 1.4e-07 30.9 3.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFO98034.1 - 0.0024 17.6 4.3 0.006 16.3 3.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFO98034.1 - 0.019 14.6 2.5 0.021 14.5 0.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger OrfB_Zn_ribbon PF07282.6 KFO98034.1 - 0.031 13.9 1.0 1.1 8.9 0.1 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-Nse PF11789.3 KFO98034.1 - 0.036 13.5 1.5 0.093 12.2 1.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KFO98034.1 - 0.041 13.4 3.4 0.072 12.6 2.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KFO98034.1 - 0.067 13.2 5.1 0.18 11.8 3.5 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFO98034.1 - 0.18 11.8 5.1 0.83 9.6 3.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KFO98034.1 - 0.56 10.1 4.1 1.3 8.9 2.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KFO98034.1 - 0.97 8.9 4.6 0.48 9.9 0.9 2.1 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_1 PF14446.1 KFO98034.1 - 3.4 7.4 5.6 2.5 7.9 0.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RNF111_N PF15303.1 KFO98035.1 - 2.8e-78 263.1 33.5 4.1e-78 262.6 23.2 1.2 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus DUF3510 PF12022.3 KFO98036.1 - 0.029 14.4 1.8 0.061 13.4 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Peptidase_M16 PF00675.15 KFO98036.1 - 1.4 8.7 5.2 2.1 8.1 0.7 2.2 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) ATP-synt_ab PF00006.20 KFO98037.1 - 1.5e-72 243.6 0.0 2.3e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFO98037.1 - 1.5e-27 96.3 0.4 3e-27 95.3 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFO98037.1 - 1.9e-18 66.4 1.9 5.2e-18 65.0 1.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.1 KFO98037.1 - 0.00029 20.8 1.8 0.00061 19.8 1.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) HAS-barrel PF09378.5 KFO98037.1 - 0.013 15.3 1.7 0.088 12.7 1.2 2.2 1 1 0 1 1 1 0 HAS barrel domain FCH PF00611.18 KFO98038.1 - 8.9e-18 64.2 0.1 8.9e-18 64.2 0.1 2.6 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain COG2 PF06148.6 KFO98038.1 - 0.89 9.4 7.7 0.8 9.5 1.3 2.8 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MitMem_reg PF13012.1 KFO98038.1 - 1 9.4 7.3 0.23 11.5 2.4 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function CENP-H PF05837.7 KFO98038.1 - 2.7 8.2 9.8 1.6 8.9 3.7 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) UCH PF00443.24 KFO98039.1 - 0.05 12.7 0.1 0.15 11.1 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase UT PF03253.9 KFO98040.1 - 1.4e-229 759.7 66.1 2.1e-115 384.7 19.9 2.0 2 0 0 2 2 2 2 Urea transporter CDP-OH_P_tran_2 PF08009.6 KFO98040.1 - 0.056 13.1 0.2 0.056 13.1 0.2 5.6 6 0 0 6 6 6 0 CDP-alcohol phosphatidyltransferase 2 Tim17 PF02466.14 KFO98040.1 - 1.4 9.0 19.4 7.7 6.5 2.7 4.3 4 0 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family DUF204 PF02659.10 KFO98040.1 - 5.2 7.2 18.8 1.1 9.4 0.1 5.6 4 2 2 6 6 6 0 Domain of unknown function DUF AT_hook PF02178.14 KFO98041.1 - 1.1 9.2 38.1 0.087 12.5 1.1 5.1 4 0 0 4 4 4 0 AT hook motif Ion_trans PF00520.26 KFO98042.1 - 3.9e-34 117.6 14.0 6.5e-34 116.9 9.7 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.6 KFO98042.1 - 2.5e-30 104.2 1.7 5.9e-30 102.9 1.2 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 KFO98042.1 - 7.6e-13 48.6 0.8 2.8e-07 30.7 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO98042.1 - 4.9e-11 42.8 0.1 0.00011 22.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFO98042.1 - 3.7e-09 35.9 1.7 0.00052 19.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KFO98042.1 - 1e-06 28.4 3.3 0.054 13.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFO98042.1 - 1.1e-06 28.7 0.1 0.047 13.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.7 KFO98042.1 - 0.002 16.6 16.8 0.03 12.7 11.7 2.4 1 1 0 1 1 1 1 Polycystin cation channel Homeobox PF00046.24 KFO98043.1 - 6.1e-22 76.9 2.5 1.2e-21 76.0 1.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO98043.1 - 0.084 12.5 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Homeobox KN domain PDZ_2 PF13180.1 KFO98045.1 - 1.3e-08 34.5 0.1 3.3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain C1_1 PF00130.17 KFO98045.1 - 8.9e-08 31.7 15.0 1.9e-07 30.7 10.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PDZ PF00595.19 KFO98045.1 - 2.7e-07 30.6 0.1 8.3e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF2404 PF10296.4 KFO98045.1 - 0.00033 20.7 0.0 0.00078 19.5 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) GRASP55_65 PF04495.9 KFO98045.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain MFS_1 PF07690.11 KFO98046.1 - 1.8e-44 151.9 38.7 2.3e-37 128.5 19.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFO98046.1 - 6.2e-12 44.8 23.7 3.6e-09 35.7 1.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.14 KFO98046.1 - 0.0092 14.5 18.3 0.006 15.1 5.0 2.9 2 1 0 2 2 2 2 LacY proton/sugar symporter Ion_trans_2 PF07885.11 KFO98047.1 - 7.7e-31 105.6 21.0 7.2e-19 67.2 2.9 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 KFO98047.1 - 9.4e-05 21.7 21.9 0.00012 21.4 3.4 2.6 2 1 0 2 2 2 2 Ion transport protein UBN2_2 PF14227.1 KFO98047.1 - 0.022 14.3 0.7 0.14 11.6 0.0 2.5 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Homeobox PF00046.24 KFO98048.1 - 1.3e-22 79.1 7.3 1.8e-22 78.6 5.1 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO98048.1 - 0.012 15.2 0.1 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 KFO98048.1 - 0.015 14.3 0.4 0.029 13.4 0.3 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_AsnC-type PF13404.1 KFO98048.1 - 0.08 12.4 0.1 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain CENP-B_N PF04218.8 KFO98048.1 - 0.11 11.8 1.5 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain MFMR PF07777.6 KFO98048.1 - 7 6.5 6.6 6.1 6.7 3.3 1.6 2 0 0 2 2 2 0 G-box binding protein MFMR DUF972 PF06156.8 KFO98049.1 - 0.023 15.0 5.9 0.023 15.0 4.1 6.3 3 2 3 6 6 6 0 Protein of unknown function (DUF972) FUSC PF04632.7 KFO98049.1 - 2.8 6.2 3.5 2.5 6.4 1.0 1.9 3 0 0 3 3 3 0 Fusaric acid resistance protein family Enolase_C PF00113.17 KFO98050.1 - 1.1e-25 90.2 0.0 1.4e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFO98050.1 - 2.1e-14 53.5 0.6 8.1e-08 32.2 0.0 2.7 3 0 0 3 3 3 2 Enolase, N-terminal domain HSP70 PF00012.15 KFO98051.1 - 5.9e-06 24.4 0.0 0.07 11.0 0.0 3.2 3 0 0 3 3 3 3 Hsp70 protein Exonuc_X-T_C PF08411.5 KFO98051.1 - 0.1 11.6 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal FGGY_C PF02782.11 KFO98051.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Lipase PF00151.14 KFO98052.1 - 6.7e-61 206.3 0.0 8.2e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 KFO98052.1 - 2.4e-09 37.5 0.3 3.7e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain Lipase PF00151.14 KFO98053.1 - 5.5e-53 180.3 0.0 6.6e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Lipase Lipase PF00151.14 KFO98054.1 - 1.5e-58 198.6 0.0 1.7e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFO98054.1 - 3.4e-06 27.1 0.1 4.2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFO98054.1 - 0.00071 19.3 0.0 0.00078 19.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CENP-F_leu_zip PF10473.4 KFO98055.1 - 0.0017 18.1 17.4 0.0017 18.1 12.1 2.6 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 KFO98055.1 - 0.014 15.7 6.5 0.014 15.7 4.5 2.5 2 2 1 3 3 3 0 Syntaxin 6, N-terminal PilJ PF13675.1 KFO98055.1 - 0.055 13.7 1.2 0.23 11.7 0.8 1.9 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 KFO98055.1 - 0.057 12.5 1.3 0.055 12.6 0.3 1.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein HALZ PF02183.13 KFO98055.1 - 0.061 13.0 0.8 0.061 13.0 0.6 5.0 5 1 1 6 6 6 0 Homeobox associated leucine zipper Spc24 PF08286.6 KFO98055.1 - 0.27 10.9 22.4 0.063 12.9 2.6 3.2 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Serine_rich PF08824.5 KFO98055.1 - 0.58 9.8 6.8 0.99 9.1 2.6 2.3 1 1 2 3 3 3 0 Serine rich protein interaction domain PRP1_N PF06424.7 KFO98055.1 - 0.89 9.8 14.8 31 4.8 10.3 2.5 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Mnd1 PF03962.10 KFO98055.1 - 0.93 9.1 22.8 0.26 10.9 5.0 2.1 1 1 1 2 2 2 0 Mnd1 family RSD-2 PF07547.8 KFO98055.1 - 1.5 8.9 4.7 6.4 6.9 0.2 2.7 2 1 1 3 3 3 0 RSD-2 N-terminal domain ADIP PF11559.3 KFO98055.1 - 2.8 7.8 22.8 0.28 11.0 8.3 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 KFO98055.1 - 5.6 6.3 10.5 1 8.6 4.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF4140 PF13600.1 KFO98055.1 - 6.7 7.2 12.2 6.3 7.3 1.7 3.4 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.5 KFO98055.1 - 6.7 6.8 18.3 0.33 11.0 2.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.4 KFO98055.1 - 7.1 6.6 19.2 0.1 12.5 2.6 3.4 2 1 1 3 3 3 0 Haemolysin XhlA GDNF PF02351.11 KFO98056.1 - 1.3e-40 137.7 46.1 1.2e-18 67.3 4.4 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain Kelch_4 PF13418.1 KFO98057.1 - 5.7e-28 96.4 8.4 1.5e-05 24.6 0.1 6.2 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO98057.1 - 3.5e-24 84.2 19.6 1.2e-07 31.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KFO98057.1 - 4.3e-23 80.5 11.0 0.00021 20.7 0.1 6.0 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 KFO98057.1 - 1.9e-22 78.4 13.6 4.4e-05 23.4 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KFO98057.1 - 2.3e-19 68.9 7.3 3e-05 24.0 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Lectin_C PF00059.16 KFO98057.1 - 1.1e-16 61.4 0.1 1.1e-16 61.4 0.1 4.1 5 1 0 5 5 2 1 Lectin C-type domain PSI PF01437.20 KFO98057.1 - 1.1e-15 57.4 54.3 6.5e-11 42.2 6.1 7.8 7 1 0 7 7 6 5 Plexin repeat Kelch_2 PF07646.10 KFO98057.1 - 4.9e-12 45.1 7.7 0.015 15.0 0.1 5.5 5 0 0 5 5 5 3 Kelch motif CUB PF00431.15 KFO98057.1 - 1.7e-11 44.1 0.0 4.4e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 CUB domain EGF_2 PF07974.8 KFO98057.1 - 6.5e-05 22.9 10.0 6.5e-05 22.9 7.0 8.6 7 1 0 7 7 3 2 EGF-like domain Laminin_EGF PF00053.19 KFO98057.1 - 8.9e-05 22.3 18.3 8.9e-05 22.3 12.7 8.5 5 3 2 7 7 4 2 Laminin EGF-like (Domains III and V) TruB_N PF01509.13 KFO98058.1 - 8.6e-50 168.7 0.0 1.1e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) RAI16-like PF10257.4 KFO98059.1 - 4.9e-131 436.8 3.5 6.1e-131 436.5 2.4 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein LIM PF00412.17 KFO98060.1 - 1.4e-43 146.7 42.9 1.2e-14 54.1 1.3 5.0 4 1 1 5 5 5 4 LIM domain VHP PF02209.14 KFO98060.1 - 1.9e-17 62.6 0.7 3.1e-17 61.9 0.5 1.3 1 0 0 1 1 1 1 Villin headpiece domain VWA PF00092.23 KFO98061.1 - 3.9e-92 306.8 0.0 3e-38 131.3 0.0 3.0 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.1 KFO98061.1 - 1e-30 107.0 0.1 2.5e-10 40.7 0.2 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain EGF PF00008.22 KFO98061.1 - 3.3e-14 52.4 24.7 2.7e-08 33.6 6.1 2.6 2 0 0 2 2 2 2 EGF-like domain VWA_3 PF13768.1 KFO98061.1 - 9.5e-10 38.3 0.0 0.013 15.2 0.0 3.3 3 0 0 3 3 3 3 von Willebrand factor type A domain Med25_VWA PF11265.3 KFO98061.1 - 0.038 13.0 0.0 13 4.7 0.0 2.9 3 0 0 3 3 3 0 Mediator complex subunit 25 von Willebrand factor type A FXa_inhibition PF14670.1 KFO98061.1 - 0.46 10.6 19.6 3.5 7.8 3.9 2.9 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site EGF_2 PF07974.8 KFO98061.1 - 3.5 7.8 29.6 4.7 7.4 8.1 2.8 2 0 0 2 2 2 0 EGF-like domain TPR_MLP1_2 PF07926.7 KFO98062.1 - 9.5e-06 25.3 22.5 9.5e-06 25.3 15.6 8.7 3 1 6 9 9 9 5 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFO98062.1 - 0.00083 19.0 29.8 0.00083 19.0 20.7 8.8 3 1 4 8 8 8 3 IncA protein DivIVA PF05103.8 KFO98062.1 - 0.008 16.2 16.8 0.008 16.2 11.6 9.5 4 1 6 10 10 10 2 DivIVA protein Reo_sigmaC PF04582.7 KFO98062.1 - 0.32 10.1 26.6 0.12 11.4 0.3 4.4 2 1 2 4 4 4 0 Reovirus sigma C capsid protein NHL PF01436.16 KFO98063.1 - 4.5e-33 111.5 4.9 1.6e-06 27.7 0.0 7.9 10 0 0 10 10 10 4 NHL repeat Thioredoxin_8 PF13905.1 KFO98063.1 - 4.9e-11 42.5 0.0 1.3e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Arylesterase PF01731.15 KFO98063.1 - 5.2e-07 29.5 0.0 0.083 12.8 0.0 4.1 4 0 0 4 4 4 2 Arylesterase SGL PF08450.7 KFO98063.1 - 7.1e-07 28.8 0.1 0.00018 20.9 0.0 4.1 3 2 0 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region AhpC-TSA PF00578.16 KFO98063.1 - 2.6e-05 23.9 0.0 5.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KFO98063.1 - 0.00058 20.0 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFO98063.1 - 0.0015 18.1 0.0 0.0057 16.1 0.0 2.0 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.15 KFO98063.1 - 0.0042 16.7 0.0 0.14 11.8 0.1 2.4 1 1 1 2 2 2 1 Thioredoxin DRMBL PF07522.9 KFO98064.1 - 8.9e-29 99.7 1.1 4.2e-28 97.5 0.0 2.5 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFO98064.1 - 2.7e-08 33.5 0.4 8.3e-08 32.0 0.0 2.0 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KFO98064.1 - 0.005 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KFO98064.1 - 0.25 10.9 1.2 0.93 9.1 0.8 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PH PF00169.24 KFO98065.1 - 1.5e-07 31.5 0.2 3.1e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFO98065.1 - 2.1e-06 27.9 0.1 5.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFO98065.1 - 0.001 19.0 0.2 0.078 13.0 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 KFO98065.1 - 0.09 12.7 0.4 0.39 10.6 0.3 2.0 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Trypsin PF00089.21 KFO98066.1 - 1.5e-67 227.3 0.1 2e-67 226.9 0.1 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFO98066.1 - 3.7e-20 71.7 4.7 1.4e-19 69.9 3.2 2.1 1 0 0 1 1 1 1 Kringle domain EGF PF00008.22 KFO98066.1 - 4.1e-14 52.2 42.2 2.1e-07 30.7 4.4 4.8 4 0 0 4 4 4 3 EGF-like domain Trypsin_2 PF13365.1 KFO98066.1 - 0.00011 22.2 0.0 0.00023 21.1 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain EGF_2 PF07974.8 KFO98066.1 - 0.002 18.2 44.2 0.01 15.9 7.5 4.7 4 0 0 4 4 4 2 EGF-like domain DUF316 PF03761.10 KFO98066.1 - 0.0082 15.5 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF316) stn_TNFRSF12A PF12191.3 KFO98066.1 - 0.014 15.4 0.4 0.051 13.6 0.3 1.9 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Plasmod_Pvs28 PF06247.6 KFO98066.1 - 7 6.1 26.7 3 7.3 15.1 2.4 2 0 0 2 2 2 0 Plasmodium ookinete surface protein Pvs28 RVT_1 PF00078.22 KFO98067.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CTNNB1_binding PF08347.6 KFO98068.1 - 2.7e-36 125.7 9.9 2.7e-36 125.7 6.9 3.2 3 1 0 3 3 3 1 N-terminal CTNNB1 binding HMG_box PF00505.14 KFO98068.1 - 4.1e-22 78.2 1.0 8e-22 77.2 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO98068.1 - 8.1e-08 32.5 1.5 1.7e-07 31.5 1.1 1.5 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KFO98068.1 - 0.086 12.1 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 V-SNARE_C PF12352.3 KFO98069.1 - 2.6e-22 78.6 6.0 8.7e-21 73.7 3.9 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 KFO98069.1 - 1.1e-18 67.1 4.6 1.1e-18 67.1 3.2 2.7 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Laminin_II PF06009.7 KFO98069.1 - 0.0092 15.7 0.6 0.62 9.8 0.0 2.2 2 0 0 2 2 2 1 Laminin Domain II Sec8_exocyst PF04048.9 KFO98069.1 - 0.045 13.3 1.4 2.4 7.7 0.1 2.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.6 KFO98069.1 - 0.047 13.7 6.2 1.2 9.1 0.4 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Peptidase_S46 PF10459.4 KFO98069.1 - 0.062 11.7 6.1 0.069 11.5 4.2 1.0 1 0 0 1 1 1 0 Peptidase S46 Sec20 PF03908.8 KFO98069.1 - 0.25 11.0 1.8 1.4 8.7 0.1 2.4 2 1 0 2 2 2 0 Sec20 TBCA PF02970.11 KFO98069.1 - 1.1 9.4 10.4 3.6 7.7 1.1 2.6 2 1 1 3 3 3 0 Tubulin binding cofactor A Metal_resist PF13801.1 KFO98069.1 - 1.4 8.8 9.2 3.7 7.5 0.3 2.8 2 2 0 2 2 2 0 Heavy-metal resistance TMPIT PF07851.8 KFO98069.1 - 4.3 6.3 7.2 7.1 5.5 0.7 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF501 PF04417.7 KFO98069.1 - 7.4 6.4 9.4 1.5 8.6 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF501) zf-DHHC PF01529.15 KFO98070.1 - 1.5e-36 125.3 9.0 3.6e-36 124.1 6.2 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase SH3_2 PF07653.12 KFO98070.1 - 3.4e-08 32.8 0.2 1.2e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFO98070.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain GSAP-16 PF14959.1 KFO98070.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 gamma-Secretase-activating protein C-term Rax2 PF12768.2 KFO98070.1 - 2.7 7.1 4.8 4.5 6.4 1.1 2.1 1 1 1 2 2 2 0 Cortical protein marker for cell polarity AMP-binding PF00501.23 KFO98071.1 - 1.3e-104 349.9 0.0 1.8e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO98071.1 - 0.0081 17.0 0.1 0.11 13.5 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zona_pellucida PF00100.18 KFO98072.1 - 7.2e-40 137.0 6.6 8.9e-40 136.7 4.6 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Acyltransferase PF01553.16 KFO98073.1 - 2.5e-22 78.7 0.0 6.6e-22 77.3 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase PTN_MK_C PF01091.13 KFO98073.1 - 0.096 12.6 1.2 0.23 11.4 0.8 1.6 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, C-terminal domain 7tm_1 PF00001.16 KFO98074.1 - 4.5e-83 278.3 0.1 6.3e-83 277.8 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO98074.1 - 8.2e-11 41.5 13.3 1.6e-06 27.4 3.8 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO98074.1 - 3.2e-06 26.4 15.9 9.5e-06 24.9 5.6 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx T2SM PF04612.7 KFO98074.1 - 0.037 13.8 0.1 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M LRR_4 PF12799.2 KFO98075.1 - 5.9e-64 210.8 83.7 1.4e-09 37.3 2.3 11.5 5 3 8 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO98075.1 - 1.8e-52 174.8 68.6 4.2e-11 42.4 4.1 9.7 3 2 8 11 11 11 11 Leucine rich repeat LRR_1 PF00560.28 KFO98075.1 - 3.4e-41 132.8 62.9 0.17 12.0 0.0 19.6 20 0 0 20 20 20 16 Leucine Rich Repeat LRR_7 PF13504.1 KFO98075.1 - 5.2e-21 71.0 71.5 0.62 10.4 0.1 18.8 19 0 0 19 19 19 8 Leucine rich repeat LRR_9 PF14580.1 KFO98075.1 - 0.0016 18.0 27.3 0.25 10.9 1.8 5.1 1 1 6 7 7 7 5 Leucine-rich repeat LRR_6 PF13516.1 KFO98075.1 - 0.045 13.8 69.1 13 6.2 0.1 16.6 14 5 4 18 18 18 0 Leucine Rich repeat MA3 PF02847.12 KFO98076.1 - 6.3e-54 180.4 0.4 7.3e-28 96.5 0.2 2.1 2 0 0 2 2 2 2 MA3 domain HABP4_PAI-RBP1 PF04774.10 KFO98076.1 - 0.0053 17.2 0.1 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family zf-C2H2_jaz PF12171.3 KFO98077.1 - 0.0021 18.1 1.3 0.0038 17.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KFO98077.1 - 0.0096 15.4 2.6 0.016 14.7 1.8 1.3 1 0 0 1 1 1 1 U1 zinc finger AKAP95 PF04988.7 KFO98077.1 - 0.03 14.1 0.1 0.042 13.6 0.1 1.3 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.2 KFO98077.1 - 1 9.6 3.5 2.9 8.2 2.4 1.8 1 1 0 1 1 1 0 Zinc-finger of C2H2 type RRM_5 PF13893.1 KFO98078.1 - 1.3e-09 37.7 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98078.1 - 1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KFO98078.1 - 0.0012 18.9 0.1 0.0029 17.6 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.17 KFO98078.1 - 0.087 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.14 KFO98079.1 - 2.6e-65 219.7 15.7 5.1e-65 218.7 10.9 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFO98079.1 - 7.5e-24 84.0 0.0 2e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFO98079.1 - 2.3e-11 44.1 0.1 5.4e-07 29.8 0.1 4.7 2 2 1 5 5 5 2 AAA domain AAA_23 PF13476.1 KFO98079.1 - 1.2e-07 32.2 48.7 1.2e-07 32.2 33.8 7.5 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 KFO98079.1 - 0.00054 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KFO98079.1 - 0.12 11.5 24.1 0.21 10.7 2.3 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein FtsK_SpoIIIE PF01580.13 KFO98079.1 - 0.22 10.9 0.0 0.22 10.9 0.0 3.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_13 PF13166.1 KFO98079.1 - 0.32 9.4 0.0 0.32 9.4 0.0 6.3 3 2 3 6 6 6 0 AAA domain DSPc PF00782.15 KFO98080.1 - 4.7e-44 149.1 0.0 4.7e-44 149.1 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO98080.1 - 1.9e-06 27.3 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KFO98080.1 - 1.7e-05 25.1 0.0 0.00027 21.2 0.0 2.7 2 1 0 2 2 2 1 Rhodanese-like domain Kelch_3 PF13415.1 KFO98080.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain CDKN3 PF05706.7 KFO98080.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KFO98080.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate SMN PF06003.7 KFO98081.1 - 6.1e-17 61.5 3.9 1.1e-16 60.7 2.7 1.7 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 KFO98081.1 - 3.9e-05 23.4 0.4 0.00022 21.0 0.0 2.4 2 1 1 3 3 3 1 Tudor domain HLH PF00010.21 KFO98082.1 - 1.8e-12 46.7 1.3 1.1e-10 41.0 1.0 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APG6 PF04111.7 KFO98082.1 - 0.0027 16.8 3.0 0.0032 16.5 2.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.9 KFO98082.1 - 0.036 13.6 2.4 0.044 13.3 1.6 1.3 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 KFO98082.1 - 0.047 12.9 0.1 0.057 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uds1 PF15456.1 KFO98082.1 - 0.37 10.7 7.9 0.056 13.4 1.3 2.2 2 1 0 2 2 2 0 Up-regulated During Septation EMP24_GP25L PF01105.19 KFO98082.1 - 4.2 7.0 5.6 0.62 9.7 0.8 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.10 KFO98082.1 - 4.7 6.7 7.3 0.7 9.4 2.3 1.7 2 0 0 2 2 2 0 Septum formation initiator Aldolase_II PF00596.16 KFO98083.1 - 1.4e-37 129.0 0.1 2.4e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Lge1 PF11488.3 KFO98083.1 - 0.23 11.6 4.4 2.3 8.4 0.3 3.0 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 Peptidase_M24 PF00557.19 KFO98084.1 - 1.2e-42 145.8 0.0 1.7e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KFO98084.1 - 1.4e-19 70.8 0.0 3.8e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain RVT_1 PF00078.22 KFO98085.1 - 4.2e-10 39.3 0.0 7.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PKD PF00801.15 KFO98086.1 - 4.1e-11 42.4 4.4 1.1e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 PKD domain BNR PF02012.15 KFO98086.1 - 0.0033 16.9 12.9 3.9 7.7 0.1 5.7 5 0 0 5 5 5 3 BNR/Asp-box repeat ASC PF00858.19 KFO98089.1 - 7.4e-124 413.7 0.3 8.5e-124 413.5 0.2 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.19 KFO98093.1 - 5.3e-33 114.3 0.0 5.8e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TNFR_c6 PF00020.13 KFO98094.1 - 1.6e-28 98.4 50.2 1.2e-09 38.0 3.9 4.1 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFO98094.1 - 0.016 14.8 9.8 0.016 14.8 6.8 4.7 3 1 0 3 3 3 0 GCC2 and GCC3 DUF3762 PF12591.3 KFO98094.1 - 0.029 14.4 0.1 0.062 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Neurexophilin PF06312.7 KFO98095.1 - 8.6e-99 329.1 3.7 9.6e-99 329.0 2.5 1.0 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.14 KFO98095.1 - 0.0064 17.0 0.5 0.46 11.0 0.0 2.2 1 1 1 2 2 2 1 Filamin/ABP280 repeat NigD PF12667.2 KFO98095.1 - 0.023 14.5 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 NigD-like protein CHORD PF04968.7 KFO98095.1 - 2.8 8.2 8.1 0.22 11.7 2.4 1.7 2 0 0 2 2 2 0 CHORD fn3 PF00041.16 KFO98096.1 - 9.2e-30 102.6 17.7 2.3e-10 40.4 0.0 5.2 5 0 0 5 5 5 3 Fibronectin type III domain Sod_Fe_C PF02777.13 KFO98097.1 - 1.8e-44 149.8 0.1 3.3e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFO98097.1 - 5e-33 113.2 3.1 7.7e-33 112.6 2.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Fmp27_WPPW PF10359.4 KFO98098.1 - 0.0013 17.2 9.0 0.0013 17.2 6.2 2.2 1 1 2 3 3 3 1 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.1 KFO98098.1 - 0.011 14.1 17.4 0.018 13.5 12.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1978 PF09321.5 KFO98098.1 - 0.07 12.5 14.6 0.02 14.3 3.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1978) Atg14 PF10186.4 KFO98098.1 - 0.89 8.4 25.7 1.9 7.3 6.5 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 KFO98098.1 - 1.2 9.0 34.9 0.47 10.3 5.2 3.7 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Lipoprotein_7 PF01540.11 KFO98098.1 - 1.4 7.8 8.1 5.7 5.8 5.6 1.9 1 1 0 1 1 1 0 Adhesin lipoprotein DUF1515 PF07439.6 KFO98098.1 - 2.3 8.0 5.2 0.66 9.8 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) APG6 PF04111.7 KFO98098.1 - 2.7 6.9 27.8 1.3 7.9 4.2 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 DICT PF10069.4 KFO98098.1 - 3.4 7.2 10.7 0.27 10.7 3.3 2.2 2 1 0 2 2 2 0 Sensory domain found in DIguanylate Cyclases & Two-component systems DUF1664 PF07889.7 KFO98098.1 - 5.6 6.7 12.4 0.11 12.2 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 KFO98098.1 - 8.8 6.0 27.7 0.26 11.0 7.2 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Thiolase_N PF00108.18 KFO98099.1 - 1.9e-80 269.6 1.3 2.6e-80 269.2 0.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFO98099.1 - 6.2e-52 174.1 1.1 1.2e-51 173.3 0.8 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFO98099.1 - 0.00021 20.8 4.1 0.00031 20.2 0.6 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.7 KFO98099.1 - 0.00058 19.8 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 Dodecin ACP_syn_III_C PF08541.5 KFO98099.1 - 0.0081 16.1 0.2 0.031 14.2 0.1 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KFO98099.1 - 0.45 10.2 3.2 14 5.4 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cpn60_TCP1 PF00118.19 KFO98100.1 - 4.1e-143 477.5 13.7 4.6e-143 477.3 9.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CAF1 PF04857.15 KFO98101.1 - 1.6e-42 145.6 0.0 3e-42 144.7 0.0 1.4 1 1 0 1 1 1 1 CAF1 family ribonuclease 7tm_1 PF00001.16 KFO98102.1 - 1.6e-26 92.9 25.7 2.7e-26 92.2 17.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFO98102.1 - 6.1e-08 32.0 20.2 6.1e-08 32.0 14.0 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.10 KFO98102.1 - 0.0036 17.0 12.3 0.0036 17.0 8.5 2.7 2 1 0 3 3 3 1 Caenorhabditis serpentine receptor-like protein, class xa ISK_Channel PF02060.10 KFO98102.1 - 0.17 11.4 1.1 3.3 7.2 0.0 2.6 2 1 1 3 3 3 0 Slow voltage-gated potassium channel 7TM_GPCR_Srbc PF10316.4 KFO98102.1 - 4.2 6.5 32.2 53 2.9 0.1 3.0 1 1 2 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srbc CIMR PF00878.13 KFO98103.1 - 0 1264.0 84.5 5.6e-54 181.8 1.7 16.2 16 0 0 16 16 16 16 Cation-independent mannose-6-phosphate receptor repeat fn2 PF00040.14 KFO98103.1 - 1.4e-18 66.5 5.7 8.8e-18 64.0 4.0 2.6 1 0 0 1 1 1 1 Fibronectin type II domain PRKCSH_1 PF13015.1 KFO98103.1 - 1.9e-09 37.1 41.4 0.037 13.5 0.1 10.2 10 2 2 12 12 12 6 Glucosidase II beta subunit-like protein MFS_1 PF07690.11 KFO98104.1 - 1.2e-26 93.2 40.2 3e-26 91.9 16.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFO98104.1 - 1.6e-24 86.3 19.2 1.6e-24 86.3 13.3 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter P5-ATPase PF12409.3 KFO98104.1 - 2.4 8.0 5.2 2.5 7.9 0.9 2.6 2 0 0 2 2 2 0 P5-type ATPase cation transporter Kringle PF00051.13 KFO98105.1 - 1.7e-145 473.4 69.6 7.2e-31 106.1 5.5 5.3 5 0 0 5 5 5 5 Kringle domain Trypsin PF00089.21 KFO98105.1 - 2.9e-48 164.3 0.1 7.6e-48 162.9 0.0 1.7 1 1 1 2 2 2 1 Trypsin DUF1986 PF09342.6 KFO98105.1 - 6.2e-12 45.3 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Helicase_C PF00271.26 KFO98106.1 - 1.9e-18 66.1 0.1 1.1e-17 63.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFO98106.1 - 2.9e-18 65.9 0.1 1.2e-17 63.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFO98106.1 - 0.0016 18.3 0.0 0.0054 16.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit KOW PF00467.24 KFO98106.1 - 0.056 13.1 0.2 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 KOW motif ANF_receptor PF01094.23 KFO98106.1 - 0.06 12.1 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Osmo_CC PF08946.5 KFO98106.1 - 0.49 10.4 3.4 1.5 8.8 2.3 1.9 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Got1 PF04178.7 KFO98107.1 - 1.4e-21 76.7 15.2 1.6e-21 76.6 10.6 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 KFO98107.1 - 0.014 15.4 11.3 0.014 15.4 7.9 2.4 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Fzo_mitofusin PF04799.8 KFO98107.1 - 0.065 12.6 0.4 0.09 12.1 0.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region Aminotran_4 PF01063.14 KFO98108.1 - 5.5e-23 81.6 0.0 7.1e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV HMG_box PF00505.14 KFO98109.1 - 4.2e-22 78.1 3.6 4.2e-22 78.1 2.5 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO98109.1 - 1.2e-08 35.1 1.0 1.2e-08 35.1 0.7 3.3 4 0 0 4 4 4 1 HMG-box domain HemX PF04375.9 KFO98109.1 - 0.47 8.9 17.8 0.048 12.2 7.2 2.3 2 0 0 2 2 2 0 HemX Choline_kinase PF01633.15 KFO98110.1 - 6.8e-60 202.2 0.1 9.4e-60 201.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFO98110.1 - 2.6e-13 50.2 0.0 3.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFO98110.1 - 1.5e-05 24.3 2.7 0.00017 20.8 1.9 2.2 1 1 0 1 1 1 1 Ecdysteroid kinase Caps_assemb_Wzi PF14052.1 KFO98110.1 - 0.035 12.9 1.0 0.048 12.5 0.7 1.1 1 0 0 1 1 1 0 Capsule assembly protein Wzi Njmu-R1 PF15053.1 KFO98110.1 - 0.052 12.2 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family C2 PF00168.25 KFO98111.1 - 1.4e-11 44.0 0.3 3e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.12 KFO98111.1 - 1.3e-07 31.9 2.0 0.011 16.1 0.0 4.6 4 1 0 4 4 4 2 Putative heavy-metal-binding Glyco_transf_29 PF00777.13 KFO98112.1 - 2.6e-75 253.0 0.0 2.9e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Sulfotransfer_1 PF00685.22 KFO98113.1 - 9.4e-67 225.0 6.2 3.1e-64 216.7 4.3 2.0 1 1 0 1 1 1 1 Sulfotransferase domain DUF2167 PF09935.4 KFO98113.1 - 0.15 10.8 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) CTP_transf_3 PF02348.14 KFO98114.1 - 8.8e-51 172.5 0.0 1.3e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.2 KFO98114.1 - 3.4e-06 27.2 0.0 4.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hydrolase_3 PF08282.7 KFO98114.1 - 5.6e-06 26.1 0.5 0.00031 20.3 0.0 3.0 2 2 1 3 3 3 1 haloacid dehalogenase-like hydrolase ABC_membrane PF00664.18 KFO98115.1 - 5.6e-63 212.9 25.3 5.8e-32 111.1 3.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFO98115.1 - 2.9e-52 176.6 0.0 1e-24 87.3 0.0 3.4 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 KFO98115.1 - 1.1e-08 35.4 0.9 0.018 14.9 0.1 4.4 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 KFO98115.1 - 5.3e-07 29.0 7.3 0.015 14.5 0.1 4.3 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KFO98115.1 - 1.4e-06 27.8 0.0 0.0051 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFO98115.1 - 3e-05 23.4 0.7 0.046 13.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFO98115.1 - 7.7e-05 21.9 0.3 0.028 13.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KFO98115.1 - 0.00018 21.9 0.0 0.7 10.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KFO98115.1 - 0.0017 18.2 0.1 1.1 9.1 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KFO98115.1 - 0.0036 16.4 0.1 0.33 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.4 KFO98115.1 - 0.0042 15.7 0.7 1 7.8 0.0 3.2 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 KFO98115.1 - 0.0048 16.3 0.5 1.2 8.5 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 KFO98115.1 - 0.0064 16.6 0.1 5.5 7.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 KFO98115.1 - 0.0085 15.0 0.0 3.7 6.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KFO98115.1 - 0.0089 16.0 0.3 0.23 11.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KFO98115.1 - 0.022 13.6 0.0 2.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KFO98115.1 - 0.029 14.0 0.7 0.3 10.7 0.0 2.9 4 0 0 4 4 4 0 Archaeal ATPase ATP-synt_ab PF00006.20 KFO98115.1 - 0.032 13.7 0.5 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 KFO98115.1 - 0.079 12.4 0.1 2.3 7.6 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 KFO98115.1 - 0.23 12.2 1.0 7.7 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain FAM177 PF14774.1 KFO98115.1 - 0.33 10.8 4.7 1.4 8.8 3.3 2.1 1 0 0 1 1 1 0 FAM177 family Dynamin_N PF00350.18 KFO98115.1 - 0.34 10.7 2.2 1.1 9.0 0.0 2.8 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 KFO98115.1 - 1.8 8.8 13.5 26 5.0 0.0 3.5 2 1 0 2 2 2 0 AAA domain IRK PF01007.15 KFO98116.1 - 5.6e-161 534.9 2.8 6.8e-161 534.6 1.9 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ldh_1_N PF00056.18 KFO98117.1 - 1.2e-50 170.9 0.8 1.9e-50 170.3 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFO98117.1 - 4.9e-32 111.0 0.0 7.7e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 KFO98117.1 - 0.00011 21.6 0.0 0.00025 20.4 0.0 1.6 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glycogen_syn PF05693.8 KFO98118.1 - 0 1177.0 0.0 0 1176.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KFO98118.1 - 7.2e-07 28.7 0.0 3e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 MRVI1 PF05781.7 KFO98120.1 - 8.8e-141 469.9 9.6 9.7e-141 469.7 6.6 1.0 1 0 0 1 1 1 1 MRVI1 protein MAD PF05557.8 KFO98120.1 - 0.0018 16.4 9.7 0.0026 15.9 6.8 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein SSFA2_C PF14723.1 KFO98120.1 - 0.0027 17.4 1.0 0.0053 16.5 0.7 1.4 1 0 0 1 1 1 1 Sperm-specific antigen 2 C-terminus DUF919 PF06034.6 KFO98120.1 - 0.37 10.4 4.3 0.37 10.4 1.6 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Casc1 PF12366.3 KFO98121.1 - 7e-08 32.2 1.3 0.12 11.8 0.0 4.0 3 1 0 3 3 3 3 Cancer susceptibility candidate 1 DUF2963 PF11178.3 KFO98121.1 - 2.8 7.4 6.7 24 4.4 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) Complex1_LYR PF05347.10 KFO98122.1 - 7.9e-14 51.1 0.0 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFO98122.1 - 4.2e-12 46.0 0.2 6.3e-12 45.5 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFO98122.1 - 5e-07 30.1 0.7 6.1e-07 29.8 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like SAS4 PF15460.1 KFO98122.1 - 0.067 13.0 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Nbl1_Borealin_N PF10444.4 KFO98122.1 - 0.11 11.9 0.2 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Ras PF00071.17 KFO98123.1 - 2.5e-58 196.0 0.0 3e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98123.1 - 2.7e-20 73.0 0.0 4.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO98123.1 - 7.8e-10 38.2 0.0 9.8e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO98123.1 - 2e-08 33.8 0.2 1.5e-07 31.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFO98123.1 - 9e-06 25.6 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 KFO98123.1 - 0.00028 19.7 0.1 0.0053 15.5 0.0 2.1 2 0 0 2 2 2 1 ArgK protein Gtr1_RagA PF04670.7 KFO98123.1 - 0.0017 17.5 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFO98123.1 - 0.002 17.4 0.0 0.017 14.4 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.4 KFO98123.1 - 0.011 14.7 0.1 1.4 7.7 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KFO98123.1 - 0.013 14.9 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KFO98123.1 - 0.016 14.7 0.4 0.46 9.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KFO98123.1 - 0.026 14.6 0.1 0.73 9.9 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 KFO98123.1 - 0.026 13.9 0.0 0.075 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KFO98123.1 - 0.035 13.1 0.4 0.073 12.0 0.0 1.9 2 1 0 2 2 2 0 Septin DUF258 PF03193.11 KFO98123.1 - 0.052 12.7 0.7 0.11 11.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFO98123.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFO98123.1 - 0.1 12.5 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ThiF PF00899.16 KFO98123.1 - 0.16 11.7 0.5 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 ThiF family RA PF00788.18 KFO98124.1 - 0.00039 20.8 0.2 0.0034 17.8 0.1 2.5 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TBPIP PF07106.8 KFO98124.1 - 0.0059 16.1 15.5 0.0059 16.1 10.8 3.1 1 1 2 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 KFO98124.1 - 0.018 14.2 5.3 0.52 9.4 1.5 3.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Herpes_IE68 PF02479.11 KFO98124.1 - 0.042 13.0 4.4 0.32 10.2 0.5 2.5 2 0 0 2 2 2 0 Herpesvirus immediate early protein Tropomyosin PF00261.15 KFO98124.1 - 0.25 10.4 41.8 0.4 9.7 19.2 2.3 1 1 1 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.2 KFO98124.1 - 0.52 10.1 44.9 6.4 6.6 18.5 2.5 2 1 1 3 3 3 0 Tropomyosin like DUF3584 PF12128.3 KFO98124.1 - 1.1 6.5 33.7 1.6 5.9 23.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 KFO98124.1 - 3.5 7.5 44.4 1.7 8.6 4.5 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Sterile PF03015.14 KFO98124.1 - 5.8 7.2 8.6 0.79 10.0 1.0 2.5 2 1 1 3 3 3 0 Male sterility protein HLH PF00010.21 KFO98125.1 - 1.3e-12 47.2 1.1 2e-12 46.5 0.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFO98125.1 - 1.6e-11 43.7 1.8 2.1e-11 43.3 0.2 2.1 2 0 0 2 2 2 1 Hairy Orange Oscp1 PF10188.4 KFO98125.1 - 0.0092 15.8 0.2 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Organic solute transport protein 1 RNA_pol_Rpb4 PF03874.11 KFO98125.1 - 0.071 13.1 0.2 0.26 11.2 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb4 HTH_Mga PF08280.6 KFO98125.1 - 0.088 12.5 1.2 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain CD20 PF04103.10 KFO98126.1 - 1.4e-16 60.8 11.5 1.7e-16 60.4 7.9 1.1 1 0 0 1 1 1 1 CD20-like family DUF4064 PF13273.1 KFO98126.1 - 0.0036 17.3 0.8 0.21 11.6 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4064) DUF1686 PF07937.6 KFO98126.1 - 0.048 13.2 2.1 0.088 12.4 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) Mito_morph_reg PF14972.1 KFO98126.1 - 0.32 10.3 2.9 0.27 10.6 0.8 1.7 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator TcpE PF12648.2 KFO98126.1 - 3.9 7.6 5.7 0.4 10.8 0.6 1.9 2 0 0 2 2 2 0 TcpE family DUF3366 PF11846.3 KFO98126.1 - 5.6 6.7 7.6 9.5 6.0 0.9 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3366) zf-DHHC PF01529.15 KFO98126.1 - 6 6.2 9.0 5.7 6.2 2.8 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase RYDR_ITPR PF01365.16 KFO98127.1 - 2.3e-124 412.4 27.1 6.9e-72 241.0 1.1 3.9 3 1 0 3 3 3 2 RIH domain MIR PF02815.14 KFO98127.1 - 2.6e-70 235.8 0.2 1.5e-68 230.0 0.0 2.8 3 0 0 3 3 3 1 MIR domain Ins145_P3_rec PF08709.6 KFO98127.1 - 1.8e-69 233.0 0.1 4.4e-67 225.2 0.1 2.8 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.6 KFO98127.1 - 2e-32 111.1 4.7 2e-32 111.1 3.3 5.0 4 1 0 4 4 4 1 RyR and IP3R Homology associated Ion_trans PF00520.26 KFO98127.1 - 9.7e-10 38.0 8.7 9.7e-10 38.0 6.0 1.9 2 0 0 2 2 2 1 Ion transport protein DUF2151 PF10221.4 KFO98129.1 - 0 1033.5 3.5 0 1033.3 2.4 1.0 1 0 0 1 1 1 1 Cell cycle and development regulator DUF837 PF05769.6 KFO98130.1 - 8.2e-76 253.5 26.5 9.6e-76 253.3 18.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF837) Tho2 PF11262.3 KFO98130.1 - 0.0019 17.3 4.4 0.0019 17.3 3.1 2.0 1 1 1 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Hemerythrin PF01814.18 KFO98130.1 - 0.15 12.2 10.9 0.088 12.9 1.8 2.3 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain ZYG-11_interact PF05884.7 KFO98130.1 - 0.26 10.3 2.0 0.41 9.6 1.4 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 CotJB PF12652.2 KFO98130.1 - 0.27 11.3 2.1 0.83 9.7 0.1 2.3 2 0 0 2 2 2 0 CotJB protein FUSC PF04632.7 KFO98130.1 - 0.32 9.3 5.5 0.38 9.1 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3452 PF11934.3 KFO98130.1 - 2 7.7 4.7 2.7 7.3 2.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) bZIP_1 PF00170.16 KFO98130.1 - 2.4 8.1 22.6 1.1 9.2 0.7 4.5 3 2 1 4 4 4 0 bZIP transcription factor Mto2_bdg PF12808.2 KFO98130.1 - 4.4 7.4 17.8 2.8 8.1 3.1 3.5 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NYD-SP28_assoc PF14775.1 KFO98130.1 - 5.7 6.7 14.3 1.9 8.2 1.6 3.3 3 1 0 3 3 3 0 Sperm tail C-terminal domain DOG1 PF14144.1 KFO98130.1 - 7.6 6.6 6.8 12 6.0 0.3 3.1 2 1 1 3 3 3 0 Seed dormancy control ArsA_ATPase PF02374.10 KFO98130.1 - 7.7 5.4 12.0 0.48 9.4 1.8 2.1 1 1 1 2 2 2 0 Anion-transporting ATPase Sec20 PF03908.8 KFO98130.1 - 8.7 6.1 14.4 7.1 6.4 0.2 3.4 1 1 1 3 3 3 0 Sec20 DUF4203 PF13886.1 KFO98131.1 - 1.4e-52 178.1 30.2 1.9e-52 177.8 20.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Med21 PF11221.3 KFO98132.1 - 3.1e-24 85.5 1.6 7.4e-24 84.3 1.1 1.5 1 1 0 1 1 1 1 Subunit 21 of Mediator complex TelA PF05816.6 KFO98132.1 - 0.00011 21.0 0.8 0.00014 20.7 0.6 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Leu_zip PF15294.1 KFO98132.1 - 0.019 14.0 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 Leucine zipper Pkinase PF00069.20 KFO98133.1 - 1.2e-60 204.8 0.1 5.7e-60 202.6 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98133.1 - 2.3e-27 95.6 2.4 3.2e-19 69.0 0.1 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KFO98133.1 - 2.2e-05 24.8 0.9 4.4e-05 23.9 0.6 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFO98133.1 - 0.0007 18.6 3.3 0.0025 16.8 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 KFO98133.1 - 0.0015 17.6 0.6 0.0028 16.7 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO98133.1 - 0.0069 16.1 0.1 0.14 11.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFO98133.1 - 0.097 11.4 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PAS_11 PF14598.1 KFO98134.1 - 2.8e-28 98.0 0.1 7.2e-24 83.8 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFO98134.1 - 9.9e-24 83.3 0.0 7e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 KFO98134.1 - 1.6e-22 79.3 0.0 3.3e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFO98134.1 - 2.4e-15 55.9 3.3 3.9e-15 55.2 1.5 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFO98134.1 - 4.2e-14 52.7 0.0 9.2e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFO98134.1 - 5.4e-07 29.6 0.0 0.0047 16.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 KFO98134.1 - 0.00012 21.8 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_2 PF08446.6 KFO98134.1 - 0.024 15.0 0.0 0.07 13.5 0.0 1.7 2 0 0 2 2 2 0 PAS fold SAM_1 PF00536.25 KFO98135.1 - 2.9e-38 129.8 10.1 8.7e-17 61.0 0.5 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFO98135.1 - 1.5e-33 114.4 9.0 1.8e-14 53.3 0.0 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) ERM PF00769.14 KFO98135.1 - 0.0029 17.1 12.4 0.0029 17.1 8.6 2.7 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Integrase_DNA PF02920.10 KFO98135.1 - 0.0052 16.1 4.7 0.0052 16.1 3.3 2.3 2 0 0 2 2 2 1 DNA binding domain of tn916 integrase DUF4407 PF14362.1 KFO98135.1 - 0.0056 15.6 15.4 0.027 13.4 5.5 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4407) SAM_PNT PF02198.11 KFO98135.1 - 0.012 15.3 5.4 0.37 10.5 0.6 3.4 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain Fib_alpha PF08702.5 KFO98135.1 - 0.096 12.8 20.0 1.5 8.9 5.6 3.8 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 KFO98135.1 - 0.68 9.2 13.7 0.38 10.1 6.1 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 KFO98135.1 - 0.92 8.6 7.9 6.5 5.8 1.3 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF16 PF01519.11 KFO98135.1 - 4.5 7.5 22.4 0.063 13.5 2.0 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 Rab15_effector PF15208.1 KFO98136.1 - 4.9e-83 278.2 0.4 5.5e-83 278.0 0.2 1.0 1 0 0 1 1 1 1 Rab15 effector FAD_binding_6 PF00970.19 KFO98137.1 - 2.7e-34 117.2 0.0 4.1e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFO98137.1 - 1.5e-32 112.3 0.0 3e-32 111.4 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFO98137.1 - 7.9e-07 29.0 0.0 3.5e-05 23.7 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFO98137.1 - 0.011 15.6 0.0 0.053 13.4 0.0 2.0 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF1641 PF07849.6 KFO98137.1 - 0.087 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) XendoU PF09412.5 KFO98138.1 - 1.1e-98 329.4 0.2 1.3e-98 329.3 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.1 KFO98138.1 - 0.019 14.7 0.0 0.046 13.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial EndoU nuclease Gb3_synth PF04572.7 KFO98139.1 - 9.7e-47 158.0 1.9 1.4e-46 157.5 1.3 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 KFO98139.1 - 4.5e-22 78.3 0.0 1.3e-21 76.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFO98139.1 - 0.053 11.9 0.0 0.072 11.5 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.7 KFO98140.1 - 1.8e-46 157.1 1.3 2.5e-46 156.6 0.9 1.2 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 KFO98140.1 - 9.9e-24 83.7 0.0 2.4e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFO98140.1 - 0.064 11.7 0.0 0.082 11.3 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain ArfGap PF01412.13 KFO98141.1 - 1.4e-28 99.0 1.1 1.4e-28 99.0 0.8 2.3 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf FCH PF00611.18 KFO98142.1 - 4.4e-21 74.8 0.1 4.4e-21 74.8 0.1 3.7 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFO98142.1 - 3.1e-16 58.6 0.9 5.2e-16 57.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFO98142.1 - 3.7e-15 55.0 0.1 8.2e-15 53.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFO98142.1 - 1e-07 31.3 0.0 2.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DegS PF05384.6 KFO98142.1 - 0.28 10.3 11.2 0.071 12.3 4.7 2.2 2 1 0 2 2 2 0 Sensor protein DegS Tweety PF04906.8 KFO98142.1 - 0.41 9.0 1.3 0.68 8.2 0.9 1.3 1 0 0 1 1 1 0 Tweety TTL PF03133.10 KFO98143.1 - 2e-110 368.3 0.8 2.6e-110 367.9 0.6 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFO98143.1 - 9.6e-07 27.8 0.1 0.0018 17.1 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.1 KFO98143.1 - 0.0092 15.1 0.0 3.8 6.5 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp BRI3BP PF14965.1 KFO98144.1 - 0.051 12.9 0.4 0.067 12.5 0.0 1.5 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Acyl_transf_1 PF00698.16 KFO98145.1 - 4.8e-16 58.9 0.1 7.3e-16 58.3 0.0 1.3 1 1 0 1 1 1 1 Acyl transferase domain TspO_MBR PF03073.10 KFO98146.1 - 2.6e-51 173.0 11.8 3e-51 172.8 8.2 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF1358 PF07096.6 KFO98146.1 - 8.1 6.1 7.7 0.38 10.4 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1358) TTL PF03133.10 KFO98147.1 - 3.6e-70 236.2 0.1 5.2e-70 235.6 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family FXa_inhibition PF14670.1 KFO98148.1 - 9.5e-66 217.6 176.5 7.2e-13 48.4 6.3 12.0 12 1 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFO98148.1 - 3e-39 132.2 85.7 4.3e-09 35.8 0.6 12.0 11 0 0 11 11 11 8 Complement Clr-like EGF-like GCC2_GCC3 PF07699.8 KFO98148.1 - 1.1e-30 104.9 33.7 6e-14 51.3 6.3 6.8 7 1 1 8 8 8 3 GCC2 and GCC3 EGF_CA PF07645.10 KFO98148.1 - 2.4e-29 101.0 171.5 2.2e-09 37.1 5.9 11.8 12 0 0 12 12 12 7 Calcium-binding EGF domain EGF_3 PF12947.2 KFO98148.1 - 4.2e-23 81.0 136.8 2.7e-10 40.0 6.6 11.2 9 0 0 9 9 9 8 EGF domain EGF PF00008.22 KFO98148.1 - 7e-21 73.8 134.4 1.6e-06 27.9 3.9 11.9 11 1 0 11 11 11 9 EGF-like domain CUB PF00431.15 KFO98148.1 - 5.4e-17 61.8 0.0 5.4e-17 61.8 0.0 2.6 3 0 0 3 3 3 1 CUB domain Orbi_NS3 PF01616.11 KFO98148.1 - 0.098 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Orbivirus NS3 hEGF PF12661.2 KFO98148.1 - 6.8 7.0 52.7 0.11 12.6 0.3 10.3 9 0 0 9 9 9 0 Human growth factor-like EGF Metallophos PF00149.23 KFO98149.1 - 2.9e-12 46.4 1.5 5.1e-12 45.6 1.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFO98149.1 - 1.9e-07 31.0 0.0 3.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfotransfer_1 PF00685.22 KFO98150.1 - 3.3e-50 170.8 0.2 4.8e-50 170.2 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain FdsD PF11390.3 KFO98150.1 - 0.072 13.1 2.0 0.75 9.9 1.2 2.2 1 1 1 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD Patatin PF01734.17 KFO98151.1 - 1.4e-06 28.4 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase CDC37_C PF08564.5 KFO98151.1 - 0.028 14.2 0.1 0.18 11.6 0.0 2.1 1 1 1 2 2 2 0 Cdc37 C terminal domain Bac_surface_Ag PF01103.18 KFO98152.1 - 1e-59 202.6 4.4 1.2e-59 202.3 3.0 1.0 1 0 0 1 1 1 1 Surface antigen Surf_Ag_VNR PF07244.10 KFO98152.1 - 0.0065 16.8 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat CH PF00307.26 KFO98153.1 - 7e-22 77.5 3.7 5.6e-12 45.6 1.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFO98153.1 - 7.2e-06 25.5 0.2 0.0028 17.2 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain DUF4264 PF14084.1 KFO98153.1 - 0.029 13.7 0.1 0.08 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Shisa PF13908.1 KFO98154.1 - 0.057 13.5 22.7 0.66 10.1 15.8 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator HbrB PF08539.6 KFO98155.1 - 2.7e-36 124.8 0.3 1.4e-34 119.2 0.2 2.2 1 1 0 1 1 1 1 HbrB-like IBN_N PF03810.14 KFO98155.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain RhoGAP PF00620.22 KFO98156.1 - 4.3e-42 143.3 0.0 1.1e-41 141.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 KFO98156.1 - 6.2e-37 126.7 3.6 6.2e-37 126.7 2.5 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFO98156.1 - 1.6e-13 50.4 0.6 4e-13 49.1 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain PHD PF00628.24 KFO98157.1 - 1e-07 31.5 6.7 2.3e-07 30.4 4.7 1.6 1 0 0 1 1 1 1 PHD-finger RAI1 PF08652.6 KFO98157.1 - 0.16 11.8 2.4 0.83 9.4 1.7 2.3 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Prok-RING_1 PF14446.1 KFO98157.1 - 0.16 11.7 8.0 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Lamprin PF06403.6 KFO98158.1 - 0.024 14.3 0.1 0.075 12.7 0.0 1.6 1 1 1 2 2 2 0 Lamprin NUP50 PF08911.6 KFO98159.1 - 1.4e-26 92.6 1.1 1.4e-26 92.6 0.7 2.9 4 0 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 KFO98159.1 - 4.7e-11 42.7 0.0 8.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF2045 PF09741.4 KFO98160.1 - 2e-118 393.7 2.7 2.5e-118 393.4 1.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) SIR2_2 PF13289.1 KFO98161.1 - 2.3e-17 63.2 0.0 3.9e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 SIR2-like domain RIB43A PF05914.7 KFO98162.1 - 1.4e-110 369.5 52.7 1.5e-110 369.4 36.5 1.0 1 0 0 1 1 1 1 RIB43A EGF_CA PF07645.10 KFO98163.1 - 1.2e-69 230.0 136.6 1.3e-11 44.2 3.1 11.3 11 1 0 12 12 12 9 Calcium-binding EGF domain cEGF PF12662.2 KFO98163.1 - 3.3e-53 176.8 82.9 8.8e-09 34.8 1.5 10.6 11 0 0 11 11 11 8 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFO98163.1 - 3.2e-30 103.9 128.0 3.4e-07 30.2 4.4 11.0 10 0 0 10 10 10 8 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFO98163.1 - 5.4e-16 58.2 107.6 0.00042 20.2 4.4 11.0 10 0 0 10 10 10 9 EGF domain EGF PF00008.22 KFO98163.1 - 2.3e-10 40.2 101.0 0.00058 19.7 1.9 11.4 10 1 0 10 10 10 7 EGF-like domain ANATO PF01821.13 KFO98163.1 - 1.2e-05 25.2 5.1 1.2e-05 25.2 3.6 8.8 9 1 0 9 9 9 2 Anaphylotoxin-like domain GBP_PSP PF02425.10 KFO98163.1 - 8 6.0 14.3 1.8 8.1 0.4 4.6 5 0 0 5 5 5 0 Paralytic/GBP/PSP peptide Atx10homo_assoc PF09759.4 KFO98164.1 - 2.1e-08 33.7 4.2 0.00019 21.1 0.0 3.7 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain WAPL PF07814.8 KFO98164.1 - 0.28 9.8 7.8 1 8.0 5.4 2.3 1 1 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin 7tm_1 PF00001.16 KFO98165.1 - 2.1e-35 122.1 23.9 2.6e-35 121.8 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO98165.1 - 2.7e-11 43.1 22.5 3.4e-11 42.8 15.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PBC PF03792.8 KFO98166.1 - 1.4e-97 325.0 0.0 1.9e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.24 KFO98166.1 - 2e-18 65.7 0.5 4.4e-18 64.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO98166.1 - 2.8e-15 55.7 0.1 2.1e-14 52.9 0.0 2.4 3 0 0 3 3 3 1 Homeobox KN domain DUF1319 PF07028.6 KFO98166.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) HTH_3 PF01381.17 KFO98166.1 - 0.019 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.3 KFO98166.1 - 0.02 13.9 0.0 0.05 12.6 0.0 1.7 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sec15 PF04091.7 KFO98166.1 - 0.024 13.9 0.1 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like HTH_19 PF12844.2 KFO98166.1 - 0.032 14.3 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.8 KFO98166.1 - 0.055 12.8 0.2 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF2464 PF10240.4 KFO98167.1 - 4.7e-41 140.7 0.0 2.4e-26 92.6 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2464) E1-E2_ATPase PF00122.15 KFO98168.1 - 0.001 18.1 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase CHCH PF06747.8 KFO98169.1 - 6.6e-07 29.0 7.0 5.2e-06 26.2 0.6 2.7 2 1 1 3 3 3 1 CHCH domain Cmc1 PF08583.5 KFO98169.1 - 2.7e-05 23.8 6.3 0.0034 17.1 0.2 2.6 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 KFO98169.1 - 0.01 15.7 0.7 0.012 15.5 0.5 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa GCK PF07802.6 KFO98169.1 - 0.02 15.0 3.1 0.5 10.5 0.1 2.5 1 1 1 2 2 2 0 GCK domain Colipase-like PF15083.1 KFO98169.1 - 0.045 13.6 8.7 0.58 10.1 0.6 2.1 1 1 1 2 2 2 0 Colipase-like UPF0203 PF05254.7 KFO98169.1 - 0.046 13.5 3.1 1.6 8.6 0.4 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 KFO98169.1 - 0.047 13.7 3.1 1.7 8.6 0.1 3.0 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.4 KFO98169.1 - 0.075 13.0 8.1 0.26 11.3 2.7 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KFO98169.1 - 1.3 9.0 6.9 1.2 9.1 1.8 2.5 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb ubiquitin PF00240.18 KFO98170.1 - 1.4e-06 27.6 0.3 4.5e-06 25.9 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KFO98170.1 - 0.00032 20.8 0.2 0.0018 18.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF3589 PF12141.3 KFO98170.1 - 0.066 11.4 0.0 0.073 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3589) Rad60-SLD PF11976.3 KFO98170.1 - 0.16 11.7 0.2 0.62 9.7 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ELMO_CED12 PF04727.8 KFO98171.1 - 1.9e-49 167.4 0.2 2.8e-49 166.9 0.1 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Glyco_transf_54 PF04666.8 KFO98172.1 - 2.7e-118 394.0 0.7 3.3e-118 393.8 0.5 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Astro_capsid_p PF12226.3 KFO98172.1 - 0.13 11.5 0.1 0.84 8.8 0.0 2.2 3 0 0 3 3 3 0 Turkey astrovirus capsid protein Calreticulin PF00262.13 KFO98173.1 - 2.3e-155 516.7 17.3 2.6e-155 516.5 12.0 1.0 1 0 0 1 1 1 1 Calreticulin family DUF2205 PF10224.4 KFO98174.1 - 1.2e-33 114.5 6.5 1.4e-33 114.2 4.5 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 KFO98174.1 - 0.0024 17.5 3.0 0.0024 17.5 2.1 1.1 1 0 0 1 1 1 1 IncA protein Nse5 PF08691.5 KFO98174.1 - 0.0034 15.9 0.2 0.0034 15.9 0.1 1.1 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 DUF972 PF06156.8 KFO98174.1 - 0.0034 17.7 3.7 0.0041 17.4 2.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF972) HALZ PF02183.13 KFO98174.1 - 0.0051 16.5 6.3 0.064 12.9 0.3 2.2 1 1 1 2 2 2 2 Homeobox associated leucine zipper bZIP_1 PF00170.16 KFO98174.1 - 0.0088 15.9 1.0 0.0088 15.9 0.7 1.9 1 1 1 2 2 2 1 bZIP transcription factor DUF2683 PF10884.3 KFO98174.1 - 0.013 15.4 0.4 0.016 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) ASD2 PF08687.6 KFO98174.1 - 0.022 14.0 2.3 0.025 13.8 1.6 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Spectrin PF00435.16 KFO98174.1 - 0.037 14.3 2.8 0.046 14.0 1.9 1.1 1 0 0 1 1 1 0 Spectrin repeat DUF904 PF06005.7 KFO98174.1 - 0.061 13.6 4.8 0.089 13.0 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Syntaxin-6_N PF09177.6 KFO98174.1 - 0.066 13.6 2.1 0.088 13.2 1.4 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal APG6 PF04111.7 KFO98174.1 - 0.072 12.1 4.4 0.082 11.9 3.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3355 PF11835.3 KFO98174.1 - 0.081 12.7 0.9 0.094 12.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) DUF3450 PF11932.3 KFO98174.1 - 0.083 12.1 2.7 0.091 12.0 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.10 KFO98174.1 - 0.095 12.1 4.7 0.07 12.6 0.9 2.0 1 1 1 2 2 2 0 Septum formation initiator Seadorna_VP6 PF07407.6 KFO98174.1 - 0.11 11.2 0.5 0.11 11.2 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein V_ATPase_I PF01496.14 KFO98174.1 - 0.25 9.1 3.0 0.26 9.1 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.7 KFO98174.1 - 0.76 9.9 5.6 0.31 11.2 1.2 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.10 KFO98174.1 - 3.3 7.5 6.1 1.1 9.1 0.4 2.4 1 1 1 2 2 2 0 Basic region leucine zipper MAPEG PF01124.13 KFO98176.1 - 3.8e-08 32.9 6.6 4.4e-08 32.8 4.6 1.1 1 0 0 1 1 1 1 MAPEG family MORN PF02493.15 KFO98177.1 - 8.9e-14 50.3 18.8 0.0012 18.3 0.6 6.3 6 0 0 6 6 6 4 MORN repeat SET PF00856.23 KFO98177.1 - 7.7e-08 32.8 0.1 3.5e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 SET domain MORN_2 PF07661.8 KFO98177.1 - 0.0011 18.7 6.9 0.1 12.6 0.0 4.7 6 0 0 6 6 6 2 MORN repeat variant NARP1 PF12569.3 KFO98178.1 - 9.4e-199 661.4 19.8 9.4e-199 661.4 13.7 2.0 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 KFO98178.1 - 2.8e-16 58.5 5.3 0.009 16.5 0.0 8.6 6 3 3 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFO98178.1 - 1.7e-15 55.6 23.2 0.0005 19.7 0.1 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFO98178.1 - 2.7e-14 53.2 19.5 0.0045 17.3 0.2 6.5 5 2 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFO98178.1 - 1.4e-11 43.8 28.9 1.1e-05 24.9 0.3 7.5 5 1 2 8 8 7 3 TPR repeat TPR_16 PF13432.1 KFO98178.1 - 4.6e-11 43.0 16.8 0.0027 18.3 0.2 6.0 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFO98178.1 - 1.3e-09 37.1 24.1 0.002 17.6 0.1 8.9 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFO98178.1 - 1.6e-09 37.5 17.1 0.026 14.4 0.4 6.9 5 2 2 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KFO98178.1 - 2.6e-08 33.8 30.9 0.00048 20.1 0.5 6.9 4 2 4 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFO98178.1 - 7.1e-07 28.5 29.2 0.0037 16.9 0.1 8.3 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFO98178.1 - 5.2e-05 23.0 6.4 0.18 11.6 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFO98178.1 - 8.3e-05 22.6 0.1 4.3 8.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFO98178.1 - 0.00027 20.4 15.2 0.21 11.4 0.1 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO98178.1 - 0.002 18.4 13.2 6.6 7.4 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 KFO98178.1 - 0.0032 16.5 15.0 0.0043 16.1 2.4 4.5 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFO98178.1 - 0.022 14.5 2.1 11 5.9 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFO98178.1 - 0.063 13.1 7.3 19 5.1 0.1 5.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 KFO98178.1 - 0.11 12.3 0.0 0.11 12.3 0.0 5.4 6 1 0 6 6 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 KFO98178.1 - 0.12 12.5 14.1 15 6.0 0.0 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF1510 PF07423.6 KFO98178.1 - 0.17 11.1 10.2 0.3 10.4 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1674 PF07896.7 KFO98178.1 - 2.3 8.5 5.0 6.2 7.1 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) DUF3464 PF11947.3 KFO98178.1 - 6.3 6.2 7.8 11 5.4 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) U79_P34 PF03064.11 KFO98178.1 - 9.5 5.6 13.6 16 4.9 9.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ets PF00178.17 KFO98180.1 - 4.2e-35 119.7 2.6 6.7e-35 119.0 1.8 1.3 1 0 0 1 1 1 1 Ets-domain Elf-1_N PF12310.3 KFO98180.1 - 1.1e-33 115.4 3.5 1.1e-33 115.4 2.4 2.6 2 0 0 2 2 2 1 Transcription factor protein N terminal Exo_endo_phos PF03372.18 KFO98181.1 - 1.3e-25 90.8 0.0 1.6e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFO98181.1 - 0.00014 21.4 0.0 0.00066 19.2 0.0 2.2 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase AA_permease_2 PF13520.1 KFO98182.1 - 6.1e-62 209.5 42.7 7.5e-62 209.2 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFO98182.1 - 8.9e-32 110.0 40.6 1.4e-31 109.3 28.1 1.2 1 1 0 1 1 1 1 Amino acid permease Cadherin PF00028.12 KFO98183.1 - 3.9e-85 280.2 2.8 1.8e-18 66.5 0.0 6.4 5 1 1 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 KFO98183.1 - 3.9e-14 51.9 0.2 1.5e-12 46.9 0.1 3.5 4 0 0 4 4 4 1 Cadherin-like VEGF_C PF14554.1 KFO98183.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 VEGF heparin-binding domain FAM176 PF14851.1 KFO98183.1 - 0.067 12.8 2.5 0.088 12.4 0.7 1.9 2 0 0 2 2 2 0 FAM176 family Syndecan PF01034.15 KFO98183.1 - 0.098 12.3 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Syndecan domain Glypican PF01153.14 KFO98185.1 - 8.8e-201 668.3 0.0 1e-200 668.1 0.0 1.0 1 0 0 1 1 1 1 Glypican TGF_beta_GS PF08515.7 KFO98185.1 - 0.75 9.1 3.8 1.7 8.0 2.6 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Connexin_CCC PF10582.4 KFO98186.1 - 2.1 8.2 3.9 3.4 7.5 1.5 2.1 1 1 1 2 2 2 0 Gap junction channel protein cysteine-rich domain Tyrosinase PF00264.15 KFO98187.1 - 1.4e-32 113.6 0.0 1.9e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Epimerase PF01370.16 KFO98188.1 - 6e-58 196.0 0.1 7.2e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFO98188.1 - 2.3e-26 92.3 0.0 2.7e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KFO98188.1 - 2.3e-23 82.5 0.0 9.4e-23 80.5 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KFO98188.1 - 8.4e-21 73.9 0.0 1.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFO98188.1 - 4.2e-18 65.1 0.0 5.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFO98188.1 - 7.4e-08 32.6 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding GpcrRhopsn4 PF10192.4 KFO98189.1 - 1.5e-79 266.8 6.0 1.8e-79 266.5 4.1 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 KFO98189.1 - 2.4e-08 33.3 3.6 3.7e-08 32.6 2.4 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor PLAC8 PF04749.12 KFO98189.1 - 0.0033 17.9 9.1 0.0042 17.6 2.3 3.1 2 1 1 3 3 3 1 PLAC8 family DUF2567 PF10821.3 KFO98189.1 - 0.017 14.6 0.1 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) DUF2231 PF09990.4 KFO98189.1 - 1.1 9.5 7.9 0.71 10.2 0.4 3.1 2 1 0 3 3 3 0 Predicted membrane protein (DUF2231) ABC_membrane PF00664.18 KFO98190.1 - 9.7e-56 189.1 38.2 5.9e-32 111.1 12.7 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFO98190.1 - 1.2e-55 187.5 0.1 8.6e-30 103.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFO98190.1 - 5.2e-12 45.4 1.8 0.013 14.7 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFO98190.1 - 5.1e-08 33.2 0.0 0.065 13.1 0.0 4.5 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 KFO98190.1 - 8.8e-08 31.5 0.0 0.0073 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFO98190.1 - 1.2e-07 31.8 0.6 0.0029 17.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 KFO98190.1 - 1.7e-07 31.2 0.0 0.0034 17.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KFO98190.1 - 2.8e-07 31.0 0.1 0.0072 16.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KFO98190.1 - 4.2e-06 26.0 0.0 0.038 13.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFO98190.1 - 7.5e-06 25.8 0.0 0.011 15.5 0.0 2.7 2 0 0 2 2 2 2 Dynamin family AAA_23 PF13476.1 KFO98190.1 - 0.00016 22.0 0.0 0.63 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFO98190.1 - 0.0002 21.5 4.7 0.71 10.0 0.1 4.0 4 1 0 4 4 3 2 AAA domain Arch_ATPase PF01637.13 KFO98190.1 - 0.00078 19.2 0.2 0.1 12.3 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 KFO98190.1 - 0.00081 18.3 0.0 0.043 12.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KFO98190.1 - 0.0013 18.2 0.0 0.81 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFO98190.1 - 0.0016 18.0 0.2 6.1 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KFO98190.1 - 0.002 17.9 0.5 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 KFO98190.1 - 0.0037 16.4 0.3 1.7 7.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 KFO98190.1 - 0.0055 16.4 0.1 2 8.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KFO98190.1 - 0.0061 17.3 1.8 1.8 9.4 0.2 3.2 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KFO98190.1 - 0.0073 15.7 0.4 3 7.2 0.0 3.4 4 0 0 4 4 3 1 IstB-like ATP binding protein ArgK PF03308.11 KFO98190.1 - 0.011 14.4 0.3 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 ArgK protein DUF815 PF05673.8 KFO98190.1 - 0.022 13.6 0.2 1.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 KFO98190.1 - 0.028 13.8 0.8 3.5 7.0 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KFO98190.1 - 0.047 13.1 3.1 8.7 5.6 0.1 3.3 2 1 1 3 3 3 0 AAA-like domain AAA_33 PF13671.1 KFO98190.1 - 0.071 12.9 0.1 7 6.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 KFO98190.1 - 0.072 12.5 0.1 1 8.7 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase AAA_15 PF13175.1 KFO98190.1 - 0.076 12.0 0.0 6.3 5.7 0.0 3.3 3 1 1 4 4 4 0 AAA ATPase domain AAA_18 PF13238.1 KFO98190.1 - 0.11 12.8 0.2 8.8 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 KFO98190.1 - 0.13 11.6 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dzip-like_N PF13815.1 KFO98191.1 - 2.1e-34 117.8 0.3 2.1e-34 117.8 0.2 5.7 3 1 4 7 7 7 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-met2 PF12907.2 KFO98191.1 - 0.13 12.2 1.8 0.41 10.6 1.3 1.8 1 0 0 1 1 1 0 Zinc-binding DUF970 PF06153.6 KFO98191.1 - 0.18 11.7 0.9 2.3 8.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF970) zf-C2H2_4 PF13894.1 KFO98191.1 - 0.26 11.7 6.1 0.41 11.1 2.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KFO98191.1 - 0.46 10.7 2.8 1.3 9.2 2.0 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SlyX PF04102.7 KFO98191.1 - 9.7 6.6 32.1 5.1 7.5 3.1 5.6 4 1 0 4 4 4 0 SlyX TPR_11 PF13414.1 KFO98192.1 - 2.4e-40 135.9 23.9 5.1e-11 42.0 0.7 6.3 4 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 KFO98192.1 - 2.6e-30 101.8 24.6 0.0002 20.9 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFO98192.1 - 3.2e-30 104.1 13.4 8.6e-07 29.4 0.4 6.7 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFO98192.1 - 1.8e-29 100.0 26.0 6.2e-07 28.7 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFO98192.1 - 1.7e-25 89.0 20.6 3.8e-06 27.1 0.7 6.9 3 3 4 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.26 KFO98192.1 - 2.7e-22 78.2 5.3 3.3e-21 74.7 1.6 3.1 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.1 KFO98192.1 - 1.4e-20 71.8 11.3 0.022 15.3 0.0 9.9 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFO98192.1 - 7.8e-19 65.9 23.4 0.00012 21.5 0.1 8.7 7 3 2 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFO98192.1 - 1.3e-17 63.3 9.3 5.3e-05 23.0 0.4 6.0 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFO98192.1 - 5.9e-15 54.1 8.9 0.0045 17.0 0.0 7.3 8 0 0 8 8 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KFO98192.1 - 3.1e-14 52.8 26.9 3.9e-05 23.7 0.2 5.4 2 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFO98192.1 - 1.9e-13 50.1 25.1 0.0031 17.4 0.1 7.6 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.1 KFO98192.1 - 1.6e-11 43.8 19.0 0.077 13.4 0.0 9.6 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_21 PF09976.4 KFO98192.1 - 1.1e-09 38.4 22.4 8e-06 25.8 2.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFO98192.1 - 3.6e-09 36.5 25.1 0.064 13.3 0.1 7.6 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFO98192.1 - 7.7e-08 31.5 15.3 3.6 7.6 0.0 8.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 KFO98192.1 - 2.2e-05 23.6 16.8 0.085 11.9 0.8 5.5 1 1 4 5 5 5 2 Tetratricopeptide repeat COPI_C PF06957.6 KFO98192.1 - 0.00053 18.6 0.7 0.35 9.3 0.0 2.7 3 0 0 3 3 3 2 Coatomer (COPI) alpha subunit C-terminus Fis1_TPR_C PF14853.1 KFO98192.1 - 0.0011 18.8 13.1 0.26 11.2 0.3 6.0 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 KFO98192.1 - 0.0033 16.2 2.5 0.0033 16.2 1.8 3.6 1 1 2 4 4 3 2 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.1 KFO98192.1 - 0.062 13.5 11.7 0.12 12.6 0.3 4.5 1 1 1 4 4 4 0 Alkyl sulfatase dimerisation DUF4363 PF14276.1 KFO98192.1 - 0.098 12.3 0.1 0.098 12.3 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) MAS20 PF02064.10 KFO98192.1 - 0.14 12.0 13.7 3.9 7.3 0.0 5.0 3 2 2 5 5 5 0 MAS20 protein import receptor TPR_4 PF07721.9 KFO98192.1 - 0.3 11.6 12.5 1.1 9.8 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat UDP-g_GGTase PF06427.6 KFO98193.1 - 5.7e-78 261.0 0.4 7.1e-77 257.4 0.1 2.9 4 0 0 4 4 4 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KFO98193.1 - 4.6e-08 32.6 0.7 4.6e-08 32.6 0.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Sulfotransfer_2 PF03567.9 KFO98194.1 - 2.7e-50 171.4 1.3 2.7e-50 171.4 0.9 1.6 2 0 0 2 2 2 1 Sulfotransferase family 7tm_1 PF00001.16 KFO98195.1 - 3.9e-36 124.4 26.5 4.8e-36 124.2 18.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-CCCH PF00642.19 KFO98196.1 - 3.1e-09 36.2 28.6 0.00021 20.8 0.5 5.5 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_16 PF10294.4 KFO98197.1 - 5.3e-22 78.0 1.1 6e-20 71.4 0.8 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFO98197.1 - 0.024 15.1 0.1 0.11 13.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 KFO98197.1 - 0.028 13.4 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 KFO98197.1 - 0.035 13.4 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 KFO98197.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFO98197.1 - 0.12 11.9 0.2 0.38 10.3 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 KFO98197.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_3 PF00202.16 KFO98198.1 - 1.5e-109 365.9 0.0 1.7e-109 365.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFO98198.1 - 0.071 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II TMEM223 PF14640.1 KFO98199.1 - 2.6e-05 24.2 0.2 2.9e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 PMM PF03332.8 KFO98200.1 - 1.2e-68 230.9 0.8 1.4e-68 230.8 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DUF600 PF04634.7 KFO98200.1 - 0.09 12.7 0.1 0.26 11.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF600 CSD PF00313.17 KFO98201.1 - 6.2e-13 48.3 0.0 8.5e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KFO98201.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain USP7_ICP0_bdg PF12436.3 KFO98202.1 - 2.4e-79 266.0 0.0 2.1e-78 263.0 0.0 2.3 1 1 1 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KFO98202.1 - 4.6e-70 235.3 5.3 1.3e-66 224.0 2.4 3.4 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KFO98202.1 - 8.7e-58 195.5 0.6 1.6e-57 194.6 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO98202.1 - 7.5e-27 94.5 0.0 1.5e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KFO98202.1 - 3.7e-17 62.6 1.5 1.7e-16 60.5 0.2 2.8 3 1 0 3 3 3 1 MATH domain DUF4588 PF15251.1 KFO98203.1 - 1.5e-46 159.2 0.0 1.8e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) DUF3678 PF12435.3 KFO98203.1 - 0.1 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) NMDAR2_C PF10565.4 KFO98204.1 - 1.4e-206 688.3 36.9 1.6e-206 688.0 25.6 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus Lig_chan PF00060.21 KFO98204.1 - 3.1e-35 121.0 0.1 3.1e-35 121.0 0.1 2.2 2 0 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFO98204.1 - 3.1e-24 85.4 0.0 2.6e-23 82.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFO98204.1 - 7.9e-20 70.6 0.6 1.7e-19 69.5 0.4 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ANF_receptor PF01094.23 KFO98204.1 - 7.2e-06 25.0 0.1 1.2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region PMP22_Claudin PF00822.15 KFO98205.1 - 1.9e-48 164.2 16.0 2.2e-48 164.0 11.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO98205.1 - 3.3e-13 49.7 17.7 3.3e-13 49.6 10.9 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KFO98205.1 - 0.00052 19.6 12.3 0.001 18.6 8.5 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein Claudin_3 PF06653.6 KFO98205.1 - 0.0007 19.3 17.8 0.0015 18.2 12.3 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like L_HGMIC_fpl PF10242.4 KFO98205.1 - 0.00092 19.2 12.0 0.0013 18.7 8.3 1.2 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein SUR7 PF06687.7 KFO98205.1 - 0.0038 16.8 10.8 0.0038 16.8 7.5 3.0 1 1 1 2 2 2 1 SUR7/PalI family DUF3290 PF11694.3 KFO98205.1 - 0.063 13.0 1.0 0.14 11.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF4401 PF14351.1 KFO98205.1 - 0.27 10.1 16.0 1.6 7.6 11.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) Fig1 PF12351.3 KFO98205.1 - 0.57 10.0 9.0 0.071 12.9 3.3 1.6 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Frag1 PF10277.4 KFO98205.1 - 0.6 9.5 16.6 0.024 14.0 6.4 1.8 1 1 0 2 2 2 0 Frag1/DRAM/Sfk1 family 7TMR-DISM_7TM PF07695.6 KFO98205.1 - 1.2 8.8 18.4 0.087 12.4 7.6 2.2 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF202 PF02656.10 KFO98205.1 - 4.6 7.5 14.2 0.55 10.4 1.9 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4064 PF13273.1 KFO98205.1 - 6.2 6.9 13.4 5.8 7.0 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF4117 PF13491.1 KFO98205.1 - 8.2 5.8 8.4 0.84 9.0 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4117) ParA PF10609.4 KFO98206.1 - 5.6e-38 128.6 0.4 1.5e-37 127.3 0.2 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KFO98206.1 - 1.3e-07 31.2 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 KFO98206.1 - 0.031 13.4 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 KFO98206.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF846 PF05832.7 KFO98207.1 - 2.3e-52 176.4 14.8 2.7e-52 176.2 10.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) NACHT PF05729.7 KFO98209.1 - 1.9e-30 105.7 0.0 4.3e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.1 KFO98209.1 - 1.2e-20 71.2 8.8 0.0002 21.0 0.0 6.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.2 KFO98209.1 - 3.4e-15 55.2 7.5 8.3e-09 34.8 2.6 5.2 3 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO98209.1 - 2.2e-07 30.5 3.8 3.4e-05 23.5 0.9 4.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KFO98209.1 - 6e-06 25.5 5.1 0.33 11.1 0.0 5.5 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KFO98209.1 - 4.4e-05 23.0 2.5 15 6.3 0.0 5.6 5 0 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 KFO98209.1 - 0.00011 21.8 0.1 0.012 15.1 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat Dexa_ind PF15198.1 KFO98210.1 - 3e-43 145.6 10.2 3.3e-43 145.5 7.1 1.0 1 0 0 1 1 1 1 Dexamethasone-induced FPL PF09758.4 KFO98211.1 - 9.4e-58 194.2 12.5 2e-57 193.1 8.7 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein SOCS_box PF07525.11 KFO98212.1 - 1.8e-10 40.5 0.0 3.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 KFO98212.1 - 8.1e-10 38.3 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 SH2 domain zf-LITAF-like PF10601.4 KFO98215.1 - 1.4e-29 101.7 10.2 1.9e-29 101.3 7.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.1 KFO98215.1 - 0.0083 15.2 4.1 0.035 13.3 0.1 2.7 2 0 0 2 2 2 1 zinc-ribbon domain zf-C4_Topoisom PF01396.14 KFO98215.1 - 0.011 15.1 3.1 0.54 9.8 0.4 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.5 KFO98215.1 - 0.018 14.9 1.0 4.2 7.4 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF1610 PF07754.6 KFO98215.1 - 0.062 13.4 0.2 0.062 13.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-ISL3 PF14690.1 KFO98215.1 - 0.17 11.9 2.9 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.1 KFO98215.1 - 0.18 11.3 4.6 0.36 10.3 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 KFO98215.1 - 0.26 10.8 3.2 3.4 7.2 0.7 2.4 2 0 0 2 2 2 0 InsA N-terminal domain UPF0547 PF10571.4 KFO98215.1 - 0.37 10.5 4.4 0.63 9.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ogr_Delta PF04606.7 KFO98215.1 - 0.45 10.2 3.6 6.4 6.5 0.2 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger SNN_transmemb PF09049.5 KFO98216.1 - 2e-24 84.9 9.7 2.6e-24 84.5 6.7 1.2 1 0 0 1 1 1 1 Stannin transmembrane SNN_linker PF09050.5 KFO98216.1 - 4.7e-21 74.0 3.3 6.4e-21 73.5 2.3 1.2 1 0 0 1 1 1 1 Stannin unstructured linker SNN_cytoplasm PF09051.5 KFO98216.1 - 7.9e-21 73.4 0.6 1e-20 73.0 0.4 1.2 1 0 0 1 1 1 1 Stannin cytoplasmic CD34_antigen PF06365.7 KFO98216.1 - 0.085 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family MLANA PF14991.1 KFO98216.1 - 0.15 12.1 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A Thioredoxin PF00085.15 KFO98217.1 - 1.1e-23 82.8 0.0 1.7e-12 46.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 KFO98217.1 - 1.1e-07 31.8 1.1 0.0086 16.0 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 KFO98217.1 - 3.7e-07 30.1 0.0 0.047 13.4 0.0 4.0 3 1 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFO98217.1 - 5.3e-07 29.8 0.0 0.0099 16.0 0.0 3.1 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFO98217.1 - 3.3e-06 27.1 3.0 0.0024 17.9 0.1 3.5 3 0 0 3 3 2 2 Thioredoxin-like DUF3450 PF11932.3 KFO98217.1 - 0.027 13.7 13.4 0.06 12.5 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 KFO98217.1 - 0.027 12.3 12.8 0.041 11.7 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Redoxin PF08534.5 KFO98217.1 - 0.053 13.0 0.0 3.7 7.0 0.0 2.7 3 0 0 3 3 3 0 Redoxin OmpH PF03938.9 KFO98217.1 - 0.26 11.2 19.2 0.54 10.1 13.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF641 PF04859.7 KFO98217.1 - 0.34 10.6 15.9 0.46 10.2 4.8 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) APG6 PF04111.7 KFO98217.1 - 0.36 9.8 29.1 0.02 13.9 16.1 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 KFO98217.1 - 0.65 9.4 29.2 1 8.8 20.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FUSC PF04632.7 KFO98217.1 - 0.74 8.1 8.9 1.1 7.5 6.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3573 PF12097.3 KFO98217.1 - 3.5 6.1 5.6 5.2 5.5 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Macoilin PF09726.4 KFO98217.1 - 5.4 5.1 25.8 0.22 9.7 12.4 1.8 1 1 1 2 2 2 0 Transmembrane protein DUF342 PF03961.8 KFO98217.1 - 7.9 4.7 14.4 14 3.9 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 KFO98217.1 - 9.2 5.9 23.6 0.11 12.2 2.9 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TPR_11 PF13414.1 KFO98218.1 - 1.3e-11 43.9 4.9 3.9e-10 39.2 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFO98218.1 - 3.5e-08 32.7 3.1 0.0032 17.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFO98218.1 - 5.6e-06 25.8 1.3 0.37 10.8 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH PF00642.19 KFO98218.1 - 9.1e-05 22.0 2.0 9.1e-05 22.0 1.4 4.2 4 0 0 4 4 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.3 KFO98218.1 - 0.00016 21.6 5.3 0.00053 20.0 3.7 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding TPR_17 PF13431.1 KFO98218.1 - 0.0012 18.8 0.6 0.0036 17.3 0.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KFO98218.1 - 0.02 15.0 1.5 0.085 13.0 0.5 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-met PF12874.2 KFO98218.1 - 0.02 15.0 5.8 0.064 13.4 4.0 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type TPR_12 PF13424.1 KFO98218.1 - 0.021 14.7 2.2 3.8 7.5 0.4 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFO98218.1 - 0.11 12.3 1.5 0.51 10.2 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFO98218.1 - 0.14 12.5 0.4 0.37 11.1 0.2 1.7 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFO98218.1 - 0.2 12.4 0.4 0.51 11.0 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.14 KFO98219.1 - 3.1e-38 130.5 14.9 3.4e-38 130.4 10.3 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFO98219.1 - 0.0026 17.4 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Parvovirus coat protein VP1 SAM_1 PF00536.25 KFO98220.1 - 1.4e-11 44.3 0.1 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_4 PF15227.1 KFO98220.1 - 1.4e-08 34.4 12.4 1.4e-08 34.4 8.6 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFO98220.1 - 6e-08 32.2 13.8 1.2e-07 31.2 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.12 KFO98220.1 - 1.4e-07 31.2 0.1 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_2 PF13923.1 KFO98220.1 - 4.5e-06 26.5 14.3 9.6e-06 25.5 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO98220.1 - 5.4e-06 26.1 14.3 1.3e-05 24.8 9.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO98220.1 - 2.2e-05 24.0 8.0 3.8e-05 23.2 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFO98220.1 - 0.0037 16.8 4.6 0.0037 16.8 3.2 2.6 2 1 2 4 4 4 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KFO98220.1 - 0.0053 16.4 11.9 0.01 15.5 8.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF1435 PF07256.7 KFO98220.1 - 0.023 14.6 1.2 0.14 12.1 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1435) zf-Apc11 PF12861.2 KFO98220.1 - 0.024 14.4 4.9 0.061 13.1 3.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFO98220.1 - 0.027 14.1 8.6 0.035 13.8 4.9 2.0 2 0 0 2 2 2 0 RING-type zinc-finger SAM_PNT PF02198.11 KFO98220.1 - 0.028 14.1 0.2 0.089 12.5 0.2 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-rbx1 PF12678.2 KFO98220.1 - 0.31 11.1 9.4 0.71 10.0 6.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1244 PF06844.6 KFO98220.1 - 2.2 8.1 5.4 6.7 6.6 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) CAF1 PF04857.15 KFO98221.1 - 6.1e-69 232.2 1.4 1.2e-68 231.2 1.0 1.5 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.6 KFO98221.1 - 3.1e-46 155.2 0.4 5.8e-46 154.3 0.3 1.5 1 0 0 1 1 1 1 RNA binding domain R3H PF01424.17 KFO98221.1 - 7.5e-05 22.3 0.0 0.00034 20.2 0.0 2.2 2 0 0 2 2 2 1 R3H domain RRM_1 PF00076.17 KFO98221.1 - 0.032 13.8 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO98221.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Shisa PF13908.1 KFO98222.1 - 6e-44 150.3 2.0 7.6e-44 150.0 1.4 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Chordopox_A13L PF05961.6 KFO98222.1 - 0.013 15.4 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Metallophos PF00149.23 KFO98223.1 - 8.4e-11 41.6 2.1 1.3e-10 41.0 1.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFO98223.1 - 2.4e-08 33.9 0.0 3.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PX PF00787.19 KFO98224.1 - 1.5e-18 66.6 3.4 2e-18 66.2 0.7 2.3 3 0 0 3 3 3 1 PX domain Rootletin PF15035.1 KFO98224.1 - 0.0043 17.0 4.4 0.0043 17.0 3.0 2.7 3 1 0 3 3 3 1 Ciliary rootlet component, centrosome cohesion NYD-SP28_assoc PF14775.1 KFO98224.1 - 0.014 15.1 5.6 1.2 8.8 0.7 3.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF2968 PF11180.3 KFO98224.1 - 0.58 9.5 10.8 0.65 9.3 5.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) TSC22 PF01166.13 KFO98224.1 - 1.4 8.9 9.2 2.7 8.0 1.2 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family RUN PF02759.14 KFO98225.1 - 5.7e-24 84.3 0.1 1.1e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 RUN domain GTP_EFTU PF00009.22 KFO98226.1 - 7e-49 165.8 0.0 1.5e-48 164.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFO98226.1 - 3.1e-22 78.5 0.2 3.1e-22 78.5 0.2 2.7 4 0 0 4 4 4 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFO98226.1 - 2.6e-07 30.6 0.1 8.9e-07 28.9 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFO98226.1 - 6.8e-05 22.7 0.1 0.00018 21.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFO98226.1 - 0.021 13.5 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Arf PF00025.16 KFO98226.1 - 0.05 12.8 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 KFO98226.1 - 0.11 13.0 0.0 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KFO98226.1 - 0.14 11.6 0.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_L1 PF00687.16 KFO98227.1 - 3.9e-52 176.7 1.2 4.5e-52 176.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RRN3 PF05327.6 KFO98228.1 - 1.6e-165 551.4 0.2 2e-165 551.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 N_Asn_amidohyd PF14736.1 KFO98229.1 - 8.7e-115 382.3 0.0 9.8e-115 382.1 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Pyridoxal_deC PF00282.14 KFO98230.1 - 8.5e-15 54.0 0.0 5.6e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain DUF3585 PF12130.3 KFO98231.1 - 5.6e-31 107.3 19.0 6.7e-31 107.0 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) TRF PF08558.5 KFO98231.1 - 0.17 11.1 4.1 0.24 10.7 2.8 1.3 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) DUF1151 PF06625.6 KFO98231.1 - 0.35 10.5 12.4 0.33 10.6 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) Histone_HNS PF00816.16 KFO98231.1 - 5.9 7.4 10.2 1.3 9.6 4.7 1.7 2 1 0 2 2 2 0 H-NS histone family OST-HTH PF12872.2 KFO98232.1 - 2.4e-54 181.0 2.3 4.2e-11 42.5 0.0 8.1 8 0 0 8 8 8 6 OST-HTH/LOTUS domain Limkain-b1 PF11608.3 KFO98232.1 - 4.9e-43 144.8 0.3 1.4e-42 143.3 0.2 1.8 1 0 0 1 1 1 1 Limkain b1 NYN PF01936.13 KFO98232.1 - 7.2e-19 68.5 0.0 1.8e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 NYN domain RRM_5 PF13893.1 KFO98232.1 - 5.5e-11 42.1 0.0 1.2e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO98232.1 - 2.2e-07 30.4 0.0 0.00015 21.3 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98232.1 - 3.3e-05 23.7 0.0 0.0012 18.7 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Jnk-SapK_ap_N PF09744.4 KFO98232.1 - 0.03 14.3 0.1 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PAH PF02671.16 KFO98232.1 - 0.1 12.2 0.5 1.8 8.2 0.1 3.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat FlbD PF06289.6 KFO98232.1 - 0.16 11.3 1.9 1.7 8.0 0.2 2.7 2 0 0 2 2 2 0 Flagellar protein (FlbD) NUDE_C PF04880.8 KFO98233.1 - 3.7e-39 134.7 1.3 3.7e-39 134.7 0.9 2.2 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region DMPK_coil PF08826.5 KFO98233.1 - 0.0022 17.8 8.0 0.0022 17.8 5.5 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like WEMBL PF05701.6 KFO98233.1 - 0.076 11.4 28.9 0.099 11.0 20.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF904 PF06005.7 KFO98233.1 - 0.16 12.2 35.3 0.56 10.5 6.2 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 KFO98233.1 - 0.32 10.7 34.4 0.34 10.6 7.1 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Pepsin-I3 PF06394.8 KFO98233.1 - 0.34 10.6 7.5 0.11 12.2 2.4 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF2009 PF09418.5 KFO98233.1 - 0.36 9.5 6.0 0.34 9.6 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) DUF148 PF02520.12 KFO98233.1 - 0.52 10.1 12.5 0.085 12.6 2.2 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF1136 PF06582.7 KFO98233.1 - 0.76 9.5 4.1 1.7 8.3 0.0 3.3 3 0 0 3 3 3 0 Repeat of unknown function (DUF1136) Flagellin_N PF00669.15 KFO98233.1 - 0.81 9.4 8.2 0.45 10.3 1.5 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF972 PF06156.8 KFO98233.1 - 0.86 9.9 25.8 5.8 7.3 5.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 KFO98233.1 - 1.3 8.1 32.6 0.61 9.2 12.2 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.7 KFO98233.1 - 4.4 6.6 30.1 1.1 8.5 4.4 3.0 1 1 2 3 3 3 0 PspA/IM30 family bZIP_1 PF00170.16 KFO98233.1 - 6.4 6.8 21.7 0.52 10.3 3.0 3.9 2 1 1 3 3 3 0 bZIP transcription factor ATG16 PF08614.6 KFO98233.1 - 9.9 5.9 31.6 1.3 8.7 12.1 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FOP_dimer PF09398.5 KFO98234.1 - 1.2e-21 76.5 0.1 1.9e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Fe_hyd_SSU PF02256.12 KFO98234.1 - 0.065 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Iron hydrogenase small subunit ABC_membrane PF00664.18 KFO98235.1 - 9.1e-90 300.7 32.5 3.4e-47 161.1 11.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFO98235.1 - 1.6e-54 183.9 0.0 3.9e-29 101.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFO98235.1 - 6.4e-10 38.6 0.0 0.00011 21.5 0.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFO98235.1 - 2.6e-06 27.5 0.5 0.00016 21.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KFO98235.1 - 6.6e-06 26.6 0.5 0.0067 16.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 KFO98235.1 - 6.6e-06 25.6 0.1 0.0079 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KFO98235.1 - 1e-05 25.4 0.5 0.071 13.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 KFO98235.1 - 2.5e-05 24.4 0.4 6.6 6.5 0.3 4.4 3 1 0 3 3 3 0 AAA domain DUF258 PF03193.11 KFO98235.1 - 3.3e-05 23.1 0.7 0.0078 15.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KFO98235.1 - 0.00028 19.5 0.0 0.058 11.9 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 KFO98235.1 - 0.00036 19.6 0.9 0.0097 15.0 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 KFO98235.1 - 0.0082 15.6 3.2 0.97 9.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 KFO98235.1 - 0.016 14.7 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 KFO98235.1 - 0.018 15.8 2.9 2.9 8.7 0.0 3.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KFO98235.1 - 0.022 14.5 5.4 0.024 14.4 0.2 2.8 3 0 0 3 3 2 0 Dynamin family DUF2370 PF10176.4 KFO98235.1 - 0.037 13.3 0.1 0.3 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) T2SE PF00437.15 KFO98235.1 - 0.04 12.8 0.0 0.54 9.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KFO98235.1 - 0.043 13.4 0.7 0.27 10.9 0.0 2.4 3 0 0 3 3 2 0 Archaeal ATPase DUF87 PF01935.12 KFO98235.1 - 0.046 13.5 2.7 3.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF815 PF05673.8 KFO98235.1 - 0.068 12.0 0.5 2.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 KFO98235.1 - 0.11 12.2 1.5 2.2 8.0 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KFO98235.1 - 0.12 12.6 0.0 22 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KFO98235.1 - 0.12 11.0 0.0 8 5.1 0.0 2.5 3 0 0 3 3 3 0 ArgK protein AAA_23 PF13476.1 KFO98235.1 - 0.13 12.5 4.7 2.4 8.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KFO98235.1 - 0.14 11.5 1.3 6.8 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KFO98235.1 - 0.14 12.2 3.1 5.8 7.0 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFO98235.1 - 0.43 10.1 1.1 31 4.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain ABC_membrane PF00664.18 KFO98236.1 - 3.3e-55 187.4 26.6 3.6e-38 131.5 12.5 3.4 3 1 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFO98236.1 - 2.7e-53 179.9 0.2 3.9e-30 104.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFO98236.1 - 5.2e-11 42.1 0.0 2.6e-05 23.5 0.0 3.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFO98236.1 - 4.5e-06 26.8 0.1 1.8 8.4 0.0 4.3 3 1 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KFO98236.1 - 1.5e-05 24.4 0.6 0.15 11.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KFO98236.1 - 1.6e-05 24.4 0.9 0.0062 15.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFO98236.1 - 2.2e-05 24.5 3.1 0.014 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KFO98236.1 - 2.7e-05 23.1 0.0 0.11 11.3 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KFO98236.1 - 2.9e-05 23.9 0.0 0.069 13.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KFO98236.1 - 5.9e-05 22.2 1.6 0.022 13.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 KFO98236.1 - 6.9e-05 22.9 1.8 0.12 12.5 0.5 3.0 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFO98236.1 - 8.7e-05 23.3 0.0 0.083 13.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KFO98236.1 - 0.0001 21.4 0.1 0.037 13.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFO98236.1 - 0.0002 21.2 1.2 0.0047 16.7 0.0 3.2 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 KFO98236.1 - 0.00038 20.9 0.4 0.15 12.6 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein AAA_23 PF13476.1 KFO98236.1 - 0.0047 17.2 0.1 3.1 8.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFO98236.1 - 0.0067 16.7 0.3 0.28 11.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KFO98236.1 - 0.0076 15.0 0.3 0.98 8.1 0.1 2.4 2 0 0 2 2 2 1 ArgK protein ABC_ATPase PF09818.4 KFO98236.1 - 0.009 14.6 2.2 0.42 9.1 0.1 3.2 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 KFO98236.1 - 0.056 12.8 0.8 9.1 5.6 0.1 2.9 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 KFO98236.1 - 0.059 13.0 1.8 5.3 6.7 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KFO98236.1 - 0.065 12.7 1.3 11 5.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KFO98236.1 - 0.11 12.1 1.4 1.6 8.4 0.1 2.5 2 0 0 2 2 2 0 NTPase DUF87 PF01935.12 KFO98236.1 - 0.13 12.0 8.8 0.35 10.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 cobW PF02492.14 KFO98236.1 - 0.15 11.5 2.6 3 7.2 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 KFO98236.1 - 0.16 11.4 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2075 PF09848.4 KFO98236.1 - 0.32 9.9 2.3 14 4.5 0.0 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 KFO98236.1 - 0.36 10.4 2.3 0.76 9.4 0.1 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.7 KFO98236.1 - 0.66 9.6 9.1 9 5.9 0.2 3.8 4 0 0 4 4 4 0 NACHT domain AAA_19 PF13245.1 KFO98236.1 - 0.76 9.5 6.5 3.1 7.6 0.2 3.2 3 0 0 3 3 2 0 Part of AAA domain CarboxypepD_reg PF13620.1 KFO98237.1 - 1.1e-45 153.5 10.2 2.4e-09 37.1 0.5 9.5 9 1 0 9 9 9 7 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 KFO98237.1 - 2.3e-23 81.7 8.6 0.00092 18.9 0.0 8.8 9 0 0 9 9 9 6 Cna protein B-type domain DUF2012 PF09430.5 KFO98237.1 - 7.3e-23 80.7 0.6 1.2e-07 31.6 0.0 7.3 7 1 1 8 8 8 4 Protein of unknown function (DUF2012) DUF4480 PF13715.1 KFO98237.1 - 2.2e-22 78.9 8.5 9e-06 25.6 0.6 8.9 6 1 3 9 9 9 5 Domain of unknown function (DUF4480) fn3_3 PF14686.1 KFO98237.1 - 1.8e-15 56.7 0.0 0.016 15.3 0.0 8.1 8 0 0 8 8 8 3 Polysaccharide lyase family 4, domain II Y_Y_Y PF07495.8 KFO98237.1 - 0.00041 20.0 2.3 1.2 8.9 0.0 4.5 5 0 0 5 5 5 1 Y_Y_Y domain phage_tail_N PF08400.5 KFO98237.1 - 0.0032 17.1 1.3 4.4 7.0 0.0 5.2 6 2 0 6 6 6 1 Prophage tail fibre N-terminal DUF4198 PF10670.4 KFO98237.1 - 0.0073 16.3 3.3 21 5.0 0.1 6.0 7 0 0 7 7 7 0 Domain of unknown function (DUF4198) DUF2141 PF09912.4 KFO98237.1 - 0.011 15.3 0.0 32 4.2 0.0 4.7 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF3823 PF12866.2 KFO98237.1 - 0.02 14.4 0.1 2.1 7.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3823) Cupredoxin_1 PF13473.1 KFO98237.1 - 0.073 12.9 0.1 2.4 8.0 0.0 3.4 2 1 1 3 3 3 0 Cupredoxin-like domain KH_1 PF00013.24 KFO98238.1 - 2.8e-19 68.4 2.1 1.4e-13 50.2 0.1 2.3 2 0 0 2 2 2 2 KH domain zf-C3HC4_3 PF13920.1 KFO98238.1 - 7.8e-12 44.6 11.7 1.2e-11 44.1 8.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KH_3 PF13014.1 KFO98238.1 - 5e-10 38.7 0.1 1e-06 28.2 0.0 2.8 2 0 0 2 2 2 2 KH domain zf-C3HC4_2 PF13923.1 KFO98238.1 - 7.4e-08 32.2 13.3 1.2e-07 31.6 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO98238.1 - 4.8e-05 22.9 13.1 7.8e-05 22.2 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO98238.1 - 0.0033 17.1 11.3 0.0056 16.3 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C2HC5 PF06221.8 KFO98238.1 - 0.023 14.4 6.9 0.049 13.3 4.8 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type KH_2 PF07650.12 KFO98238.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 KH domain zf-C3HC4_4 PF15227.1 KFO98238.1 - 0.4 10.5 11.7 0.92 9.4 8.2 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFO98238.1 - 0.46 10.1 8.6 0.91 9.1 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 KFO98239.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Yae1_N PF09811.4 KFO98240.1 - 6.1e-12 44.8 32.7 5.6 6.5 22.7 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal PKD PF00801.15 KFO98241.1 - 2.2e-11 43.3 0.6 1.1e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 PKD domain BNR PF02012.15 KFO98241.1 - 0.00081 18.8 16.2 0.9 9.6 0.5 6.3 6 0 0 6 6 6 3 BNR/Asp-box repeat DUF904 PF06005.7 KFO98242.1 - 0.014 15.6 8.8 0.014 15.6 6.1 14.3 5 2 2 8 8 8 0 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 KFO98242.1 - 0.15 11.2 35.2 0.12 11.4 0.7 5.2 2 1 2 5 5 5 0 Reovirus sigma C capsid protein GP40 PF11025.3 KFO98242.1 - 1.1 8.7 5.4 0.42 10.1 1.5 1.9 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium Mab-21 PF03281.9 KFO98243.1 - 1.6e-22 80.0 3.7 2.2e-20 72.9 2.6 2.3 1 1 0 1 1 1 1 Mab-21 protein CemA PF03040.9 KFO98243.1 - 0.11 12.0 0.7 0.22 11.1 0.5 1.4 1 0 0 1 1 1 0 CemA family GST_N_3 PF13417.1 KFO98244.1 - 2.7e-23 81.9 0.0 5.9e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFO98244.1 - 3.5e-16 58.9 0.0 6.5e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFO98244.1 - 1.5e-09 37.7 0.1 2.3e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFO98244.1 - 1.2e-06 28.5 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFO98244.1 - 4.1e-06 26.5 0.0 6.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFO98244.1 - 0.00019 21.8 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KFO98244.1 - 0.00034 20.5 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Mei5 PF10376.4 KFO98247.1 - 4.4e-39 134.2 11.6 3.3e-38 131.4 8.0 1.9 1 1 0 1 1 1 1 Double-strand recombination repair protein T2SN PF01203.14 KFO98247.1 - 0.043 13.3 0.2 0.1 12.1 0.1 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein N DUF4150 PF13665.1 KFO98247.1 - 0.17 11.7 0.8 0.31 10.9 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4150) Collagen PF01391.13 KFO98248.1 - 3.1e-63 209.1 375.3 1.6e-09 37.1 23.2 17.3 10 4 5 15 15 15 15 Collagen triple helix repeat (20 copies) PKK PF12474.3 KFO98249.1 - 1.3e-69 232.4 97.6 3.5e-44 149.9 29.1 7.0 6 2 2 8 8 8 2 Polo kinase kinase Pkinase PF00069.20 KFO98249.1 - 1.3e-69 234.2 0.0 1.3e-69 234.2 0.0 4.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98249.1 - 4.3e-48 163.6 0.0 4.3e-48 163.6 0.0 3.3 4 0 0 4 4 4 1 Protein tyrosine kinase STN1_2 PF09170.5 KFO98250.1 - 1.2e-54 184.6 4.6 6.4e-54 182.3 3.2 2.0 1 1 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 tRNA_anti-codon PF01336.20 KFO98250.1 - 1.4e-08 34.5 0.1 2.9e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.4 KFO98250.1 - 1.7e-07 30.3 0.2 1.3e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 Telomere regulation protein Stn1 PX PF00787.19 KFO98251.1 - 3.6e-17 62.1 0.1 4.1e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 KFO98252.1 - 1.3e-39 133.3 20.3 3.9e-11 42.1 0.2 5.4 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.12 KFO98252.1 - 1.3e-36 123.8 10.1 5.6e-11 41.7 0.1 5.3 5 0 0 5 5 5 5 Variant SH3 domain SH3_9 PF14604.1 KFO98252.1 - 5.7e-33 112.2 17.7 5.3e-10 38.7 0.1 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_3 PF08239.6 KFO98252.1 - 3.9e-17 62.1 24.0 0.00091 19.3 0.1 5.6 5 0 0 5 5 5 5 Bacterial SH3 domain FeoA PF04023.9 KFO98252.1 - 0.14 12.0 0.0 14 5.7 0.0 3.6 4 0 0 4 4 4 0 FeoA domain SH3_6 PF12913.2 KFO98252.1 - 0.28 10.4 3.1 0.74 9.0 0.1 2.7 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type KGK PF08872.5 KFO98252.1 - 0.85 9.7 8.3 25 5.0 0.0 4.6 5 0 0 5 5 5 0 KGK domain SH3_4 PF06347.8 KFO98252.1 - 0.89 9.1 22.3 0.16 11.5 0.4 4.5 5 0 0 5 5 5 0 Bacterial SH3 domain Neuralized PF07177.7 KFO98253.1 - 8.9e-47 156.8 0.1 1.6e-30 104.7 0.0 2.6 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.1 KFO98253.1 - 7.6e-13 47.9 12.6 7.6e-13 47.9 8.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO98253.1 - 3.4e-06 26.9 16.5 3.4e-06 26.9 11.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO98253.1 - 0.37 10.5 21.9 0.026 14.2 10.3 2.8 3 0 0 3 3 3 0 zinc-RING finger domain Ca_hom_mod PF14798.1 KFO98254.1 - 6.9e-88 293.8 9.1 7.9e-88 293.6 6.3 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Ca_hom_mod PF14798.1 KFO98255.1 - 2e-91 305.4 5.3 2.3e-91 305.2 3.7 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Ca_hom_mod PF14798.1 KFO98256.1 - 4.4e-91 304.3 0.9 5.3e-91 304.0 0.6 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF996 PF06195.8 KFO98256.1 - 0.019 14.9 0.2 0.17 11.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF1218 PF06749.7 KFO98256.1 - 0.13 12.7 2.2 0.27 11.7 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Suf PF05843.9 KFO98257.1 - 1.4e-13 51.2 14.9 3.1e-08 33.6 0.6 4.5 2 2 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KFO98257.1 - 3.4e-10 40.0 0.0 0.00069 19.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFO98257.1 - 3.1e-09 36.6 3.2 0.12 13.1 0.3 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFO98257.1 - 2.3e-08 34.4 0.1 0.0057 17.2 0.3 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFO98257.1 - 1e-07 31.3 7.2 0.0011 18.0 0.6 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFO98257.1 - 1.3e-05 24.6 0.2 0.093 12.3 0.3 3.5 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 KFO98257.1 - 0.0025 17.6 5.8 0.48 10.3 0.0 3.7 1 1 3 4 4 4 2 Tetratricopeptide repeat DUF3366 PF11846.3 KFO98257.1 - 0.031 14.1 2.3 0.055 13.3 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) ATP_synth_reg PF14960.1 KFO98258.1 - 1.3e-25 88.2 0.2 1.5e-25 88.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase regulation DUF4345 PF14248.1 KFO98258.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) WD40 PF00400.27 KFO98259.1 - 2e-70 230.3 7.9 4.4e-13 48.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KFO98259.1 - 3.3e-42 143.9 6.2 5.4e-42 143.2 4.3 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 KFO98259.1 - 6.4e-09 34.4 0.9 0.016 13.3 0.0 3.8 3 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KFO98259.1 - 0.017 14.8 0.0 0.086 12.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFO98259.1 - 0.03 12.6 0.0 1.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain zf-C3HC4 PF00097.20 KFO98260.1 - 1.1e-08 34.5 11.0 1.9e-08 33.7 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO98260.1 - 4.8e-08 32.9 11.5 9.4e-08 31.9 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO98260.1 - 8.3e-06 25.5 9.4 8.3e-06 25.5 6.5 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO98260.1 - 4.8e-05 22.9 7.8 8.2e-05 22.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO98260.1 - 0.00041 19.9 10.6 0.00041 19.9 7.4 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFO98260.1 - 0.0029 17.3 2.6 0.005 16.5 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFO98260.1 - 0.017 14.9 10.1 0.037 13.9 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFO98260.1 - 0.042 13.5 6.1 0.083 12.6 4.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger C1_3 PF07649.7 KFO98260.1 - 0.2 11.6 8.7 0.3 11.1 3.0 2.6 2 0 0 2 2 2 0 C1-like domain zf-Nse PF11789.3 KFO98260.1 - 0.28 10.7 6.3 0.55 9.7 4.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.6 KFO98260.1 - 0.39 10.5 5.7 1 9.2 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.2 KFO98260.1 - 1.5 8.9 7.8 3.5 7.8 5.4 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger 5_nucleotid PF05761.9 KFO98261.1 - 1.4e-182 607.2 0.2 1.7e-182 606.9 0.1 1.1 1 0 0 1 1 1 1 5' nucleotidase family Methyltransf_31 PF13847.1 KFO98262.1 - 1.5e-35 122.0 0.0 2.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO98262.1 - 1.6e-19 70.1 0.0 3.5e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFO98262.1 - 1.8e-15 56.6 0.0 2.9e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KFO98262.1 - 7e-15 55.1 0.0 1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO98262.1 - 3.7e-14 53.2 0.0 1.1e-13 51.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO98262.1 - 1.6e-13 50.9 0.0 3.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO98262.1 - 1.8e-13 50.7 0.0 2.3e-12 47.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFO98262.1 - 2e-08 34.2 0.0 4.9e-08 33.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 KFO98262.1 - 3.4e-06 26.7 0.0 5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 KFO98262.1 - 4.8e-05 23.1 0.0 8.3e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase PrmA PF06325.8 KFO98262.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFO98262.1 - 0.0002 20.7 0.0 0.00046 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 KFO98262.1 - 0.00075 18.7 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 KFO98262.1 - 0.051 12.9 0.5 0.5 9.7 0.3 2.1 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW p450 PF00067.17 KFO98264.1 - 1.3e-141 472.2 0.0 1.5e-141 472.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WBP-1 PF11669.3 KFO98265.1 - 4.4e-50 168.0 13.8 7e-50 167.3 9.6 1.3 1 0 0 1 1 1 1 WW domain-binding protein 1 Mtc PF03820.12 KFO98266.1 - 9.6e-107 356.1 0.2 1.1e-106 355.9 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Arf PF00025.16 KFO98267.1 - 4e-72 241.1 0.0 4.5e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFO98267.1 - 1.5e-14 53.6 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFO98267.1 - 4.9e-14 51.8 0.8 2.2e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFO98267.1 - 1.5e-13 50.4 0.0 1.7e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFO98267.1 - 2.4e-13 49.8 0.0 2.9e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFO98267.1 - 5.7e-12 46.1 0.0 7.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFO98267.1 - 9.9e-10 38.4 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFO98267.1 - 4e-07 29.6 0.0 7.9e-05 22.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.24 KFO98267.1 - 0.00011 22.3 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KFO98267.1 - 0.00094 18.6 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KFO98267.1 - 0.0047 17.7 0.2 0.043 14.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KFO98267.1 - 0.01 15.7 0.1 0.024 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFO98267.1 - 0.016 15.3 0.1 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KFO98267.1 - 0.025 14.2 0.0 6.1 6.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KFO98267.1 - 0.028 14.7 0.1 0.049 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KFO98267.1 - 0.03 14.1 0.0 0.52 10.1 0.0 2.1 1 1 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 KFO98267.1 - 0.036 13.7 0.1 0.044 13.4 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase FeoB_N PF02421.13 KFO98267.1 - 0.062 12.5 0.1 0.18 11.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ArgK PF03308.11 KFO98267.1 - 0.064 12.0 0.1 6.6 5.4 0.0 2.7 2 1 0 2 2 2 0 ArgK protein cobW PF02492.14 KFO98267.1 - 0.075 12.4 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KFO98267.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.1 KFO98267.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFO98267.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter zf-C3HC4_4 PF15227.1 KFO98268.1 - 3.6e-11 42.7 8.3 3.6e-11 42.7 5.7 3.3 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFO98268.1 - 1.2e-09 37.6 6.5 1.2e-09 37.6 4.5 2.8 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO98268.1 - 1.4e-07 31.4 8.9 1.4e-07 31.4 6.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO98268.1 - 9.4e-07 28.5 8.1 9.4e-07 28.5 5.6 3.3 3 0 0 3 3 2 1 Ring finger domain CASP_C PF08172.7 KFO98268.1 - 1.7e-05 24.0 2.6 3.1e-05 23.1 1.8 1.5 1 0 0 1 1 1 1 CASP C terminal zf-RING_UBOX PF13445.1 KFO98268.1 - 2.7e-05 23.7 4.6 2.7e-05 23.7 3.2 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-B_box PF00643.19 KFO98268.1 - 0.00026 20.7 7.7 0.00026 20.7 5.3 5.2 5 1 0 5 5 4 1 B-box zinc finger zf-RING_5 PF14634.1 KFO98268.1 - 0.00086 18.9 6.6 0.00086 18.9 4.6 3.9 3 2 1 4 4 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFO98268.1 - 0.018 14.8 3.5 0.067 12.9 2.4 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.10 KFO98268.1 - 0.095 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain IncA PF04156.9 KFO98268.1 - 0.57 9.7 11.6 1.1 8.8 8.0 1.4 1 0 0 1 1 1 0 IncA protein Phasin PF05597.6 KFO98268.1 - 0.61 9.8 8.4 1.1 9.0 5.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) APG6 PF04111.7 KFO98268.1 - 1.5 7.8 12.6 2.3 7.1 8.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 KFO98268.1 - 4.1 5.7 9.8 5.9 5.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SUFU_C PF12470.3 KFO98269.1 - 1.5e-95 318.6 0.0 1.9e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Suppressor of Fused Gli/Ci N terminal binding domain SUFU PF05076.8 KFO98269.1 - 7.9e-36 123.1 0.0 1.2e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) Actin PF00022.14 KFO98270.1 - 3.7e-131 437.1 0.0 4.1e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Actin MFS_2 PF13347.1 KFO98271.1 - 3.1e-25 88.4 10.4 7.1e-25 87.2 7.2 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein FAM178 PF14816.1 KFO98274.1 - 5e-163 542.2 9.6 7.1e-163 541.6 6.6 1.1 1 0 0 1 1 1 1 Family of unknown function, FAM178 hNIFK_binding PF12196.3 KFO98274.1 - 0.44 9.9 4.9 2.6 7.5 1.6 2.5 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Sema PF01403.14 KFO98275.1 - 5.1e-117 391.0 0.0 6.7e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 Sema domain Ig_2 PF13895.1 KFO98275.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain PSI PF01437.20 KFO98275.1 - 1.2e-05 25.3 9.0 4.2e-05 23.6 6.2 2.0 1 0 0 1 1 1 1 Plexin repeat L51_S25_CI-B8 PF05047.11 KFO98276.1 - 7.9e-09 35.1 0.0 2.2e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AAA_25 PF13481.1 KFO98277.1 - 2.5e-10 40.0 0.0 6.4e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFO98277.1 - 0.00011 21.6 0.0 0.00032 20.1 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFO98277.1 - 0.00012 22.1 0.0 0.00029 20.8 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 KFO98277.1 - 0.00019 21.8 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFO98277.1 - 0.00023 20.1 0.0 0.00031 19.7 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KFO98277.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFO98277.1 - 0.0025 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 KFO98277.1 - 0.0041 16.8 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KFO98277.1 - 0.0044 16.8 0.0 0.0089 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 KFO98277.1 - 0.005 15.7 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_17 PF13207.1 KFO98277.1 - 0.012 16.4 0.4 0.067 14.0 0.2 2.2 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFO98277.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase UPF0079 PF02367.12 KFO98277.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KFO98277.1 - 0.034 14.4 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 KFO98277.1 - 0.034 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KFO98277.1 - 0.047 13.1 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 KFO98277.1 - 0.059 12.5 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.14 KFO98277.1 - 0.07 12.5 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KFO98277.1 - 0.082 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KFO98277.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 KFO98277.1 - 0.09 12.6 0.0 0.25 11.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain MutS_V PF00488.16 KFO98277.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 MutS domain V PDZ PF00595.19 KFO98278.1 - 5.7e-12 45.6 0.1 5.9e-12 45.6 0.1 1.0 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO98278.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.19 KFO98279.1 - 3.9e-37 126.2 1.0 6.9e-18 64.6 0.2 2.4 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO98279.1 - 4.6e-13 48.8 0.1 3.3e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 KFO98279.1 - 0.016 14.9 0.4 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Tricorn protease PDZ domain Mtc PF03820.12 KFO98280.1 - 5.4e-145 481.8 0.0 6e-145 481.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier I-set PF07679.11 KFO98281.1 - 1.8e-13 50.1 0.0 2.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain Kazal_1 PF00050.16 KFO98281.1 - 1.4e-06 28.2 0.2 1.4e-06 28.2 0.2 2.6 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Ig_2 PF13895.1 KFO98281.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.10 KFO98281.1 - 3.6e-05 23.6 7.8 7.2e-05 22.6 0.6 2.6 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain IGFBP PF00219.13 KFO98281.1 - 0.00012 22.4 19.7 0.00012 22.4 13.6 2.7 3 0 0 3 3 3 1 Insulin-like growth factor binding protein ig PF00047.20 KFO98281.1 - 0.00024 21.1 0.0 0.001 19.1 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO98281.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Homeobox PF00046.24 KFO98282.1 - 2.8e-23 81.3 2.9 4.1e-23 80.7 2.0 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO98282.1 - 0.00044 19.9 0.1 0.00085 18.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFO98282.1 - 0.0016 17.4 0.1 0.0022 17.0 0.1 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Remorin_C PF03763.8 KFO98282.1 - 0.054 13.0 0.8 0.054 13.0 0.5 1.6 1 1 1 2 2 2 0 Remorin, C-terminal region Terminase_5 PF06056.7 KFO98282.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) WD40 PF00400.27 KFO98283.1 - 1e-59 196.3 16.0 4e-10 39.1 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.3 KFO98283.1 - 2.7e-27 94.0 3.9 4.7e-27 93.3 2.7 1.4 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.2 KFO98283.1 - 1.1e-10 41.0 0.5 3.3e-10 39.5 0.1 2.0 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 KFO98283.1 - 5.8e-08 32.1 0.0 1.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 KFO98283.1 - 1.4e-06 27.3 1.8 0.047 12.4 0.0 3.8 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KFO98283.1 - 0.00073 17.7 9.2 0.92 7.5 0.1 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 DUF4508 PF14969.1 KFO98283.1 - 0.021 14.8 0.1 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Cellulase-like PF12876.2 KFO98283.1 - 0.092 13.2 0.0 0.79 10.2 0.0 2.6 3 0 0 3 3 3 0 Sugar-binding cellulase-like Sugar_tr PF00083.19 KFO98284.1 - 1.1e-101 340.6 24.0 1.3e-101 340.4 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFO98284.1 - 8.3e-17 60.9 35.9 7.8e-13 47.8 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol_B_palm PF14792.1 KFO98285.1 - 7.1e-34 116.2 0.0 1.9e-33 114.8 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KFO98285.1 - 1.9e-22 78.5 0.1 1e-21 76.2 0.1 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KFO98285.1 - 6e-22 77.1 0.1 2e-21 75.4 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 KFO98285.1 - 2.3e-19 69.3 0.1 5.1e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KFO98285.1 - 4.4e-06 26.7 0.0 0.087 13.0 0.0 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix domain HHH PF00633.18 KFO98285.1 - 6.5e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.18 KFO98285.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain IMS_HHH PF11798.3 KFO98285.1 - 0.14 12.2 0.2 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 IMS family HHH motif DPCD PF14913.1 KFO98286.1 - 4e-93 309.9 0.2 4.7e-93 309.6 0.1 1.0 1 0 0 1 1 1 1 DPCD protein family MucBP PF06458.7 KFO98286.1 - 0.0092 16.5 0.1 0.097 13.2 0.0 2.1 2 0 0 2 2 2 1 MucBP domain CBM_21 PF03370.8 KFO98286.1 - 0.12 12.4 0.1 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase regulatory subunit FGF PF00167.13 KFO98287.1 - 9.2e-39 131.9 1.0 1.4e-38 131.3 0.7 1.2 1 0 0 1 1 1 1 Fibroblast growth factor BPL_C PF02237.12 KFO98287.1 - 0.043 13.5 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Nucleoplasmin PF03066.10 KFO98288.1 - 1e-46 158.1 0.0 1.1e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoplasmin Nitrophorin PF02087.10 KFO98288.1 - 0.0028 17.4 0.1 0.0036 17.1 0.1 1.1 1 0 0 1 1 1 1 Nitrophorin DUF1741 PF08427.5 KFO98289.1 - 1.1e-86 290.1 5.6 1.1e-86 290.1 3.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Prominin PF05478.6 KFO98291.1 - 1.4e-108 363.5 0.2 1.6e-108 363.3 0.1 1.0 1 0 0 1 1 1 1 Prominin GrpE PF01025.14 KFO98291.1 - 0.0086 15.6 2.8 0.018 14.5 0.9 1.9 1 1 1 2 2 2 1 GrpE LIM_bind PF01803.11 KFO98292.1 - 1.9e-72 243.2 2.9 6e-72 241.6 2.0 1.8 1 1 0 1 1 1 1 LIM-domain binding protein DUF3426 PF11906.3 KFO98293.1 - 0.097 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) RRM_1 PF00076.17 KFO98294.1 - 3.8e-09 36.0 0.0 7.7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98294.1 - 1.4e-06 28.1 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO98294.1 - 4.1e-05 23.3 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Endonuc-MspI PF09208.5 KFO98294.1 - 0.042 12.9 0.1 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease MspI HTH_psq PF05225.11 KFO98295.1 - 2.3e-15 55.8 0.3 1.3e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DUF4553 PF15090.1 KFO98296.1 - 5.4e-162 539.9 47.0 5.4e-162 539.9 32.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4553) Trp_halogenase PF04820.9 KFO98296.1 - 0.23 10.0 0.1 0.4 9.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase LRR_8 PF13855.1 KFO98297.1 - 1.8e-87 287.0 77.9 1.1e-13 50.6 1.8 9.7 4 4 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 KFO98297.1 - 2.2e-56 186.7 46.2 1.2e-07 31.2 1.0 10.9 7 2 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFO98297.1 - 8.7e-36 122.4 6.0 5.1e-10 39.1 0.0 5.1 4 1 0 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFO98297.1 - 6.3e-30 98.6 46.1 0.0096 15.8 0.0 18.6 20 0 0 20 20 19 9 Leucine Rich Repeat EGF PF00008.22 KFO98297.1 - 3.6e-22 77.9 89.5 1.3e-07 31.4 4.3 8.1 8 1 0 8 8 6 5 EGF-like domain Laminin_G_2 PF02210.19 KFO98297.1 - 4.7e-22 78.3 0.1 8.2e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain LRRNT PF01462.13 KFO98297.1 - 5.9e-22 76.5 30.3 1.3e-08 34.1 1.1 5.6 4 0 0 4 4 4 3 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.18 KFO98297.1 - 3e-21 75.8 0.0 4.8e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain LRRCT PF01463.19 KFO98297.1 - 2.7e-16 58.0 11.2 0.003 17.7 0.3 7.4 5 0 0 5 5 5 4 Leucine rich repeat C-terminal domain LRR_9 PF14580.1 KFO98297.1 - 1.4e-13 50.8 12.7 0.0027 17.3 0.1 5.4 4 1 1 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.1 KFO98297.1 - 3.3e-08 32.7 52.2 2.1 8.6 0.0 16.6 15 3 1 16 16 16 3 Leucine Rich repeat LRR_7 PF13504.1 KFO98297.1 - 2.1e-06 26.9 56.5 2.1 8.9 0.1 16.2 16 0 0 16 16 16 3 Leucine rich repeat hEGF PF12661.2 KFO98297.1 - 0.00024 20.9 66.6 0.024 14.6 2.0 9.1 9 0 0 9 9 8 5 Human growth factor-like EGF Laminin_G_3 PF13385.1 KFO98297.1 - 0.00066 19.9 0.4 0.0013 18.9 0.3 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.10 KFO98297.1 - 0.0012 18.7 7.4 0.0012 18.7 5.1 8.7 7 1 2 9 9 7 2 Calcium-binding EGF domain RhoGAP PF00620.22 KFO98298.1 - 1.1e-35 122.5 0.5 1.1e-35 122.5 0.3 1.7 2 0 0 2 2 2 1 RhoGAP domain NUC173 PF08161.7 KFO98299.1 - 2.7e-79 265.1 0.1 1.1e-75 253.3 0.0 3.4 4 0 0 4 4 4 2 NUC173 domain HEAT PF02985.17 KFO98299.1 - 0.0022 17.9 0.4 6.7 7.0 0.1 4.0 3 0 0 3 3 3 2 HEAT repeat DUF3136 PF11334.3 KFO98299.1 - 0.0057 16.0 0.1 2.6 7.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3136) F-protein PF00469.15 KFO98299.1 - 0.93 8.8 5.3 1.8 7.8 3.7 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef His_Phos_1 PF00300.17 KFO98300.1 - 3.7e-41 140.8 0.0 4.7e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EXOSC1 PF10447.4 KFO98301.1 - 5.3e-27 93.5 0.1 9.3e-27 92.8 0.1 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 KFO98301.1 - 0.025 14.6 0.1 0.23 11.5 0.1 2.1 1 1 0 1 1 1 0 S1 RNA binding domain zf-DHHC PF01529.15 KFO98302.1 - 3.7e-31 107.8 15.8 3.7e-31 107.8 10.9 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase Cytochrom_B_N PF00033.14 KFO98302.1 - 0.0012 18.2 10.7 0.15 11.3 4.2 2.3 2 0 0 2 2 2 2 Cytochrome b(N-terminal)/b6/petB MMS19_C PF12460.3 KFO98303.1 - 4.1e-116 388.1 14.5 2.2e-115 385.7 0.2 3.8 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 KFO98303.1 - 1.9e-96 322.3 0.1 1.9e-96 322.3 0.1 3.0 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 KFO98303.1 - 4.7e-07 29.9 13.7 0.00018 21.7 0.3 5.6 5 1 0 5 5 5 2 HEAT repeats Anticodon_1 PF08264.8 KFO98303.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA HEAT PF02985.17 KFO98303.1 - 1.5 9.0 7.6 1.3 9.2 0.1 4.9 4 0 0 4 4 4 0 HEAT repeat ubiquitin PF00240.18 KFO98304.1 - 1.7e-12 46.5 0.1 2.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFO98304.1 - 2.1e-05 24.1 0.1 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ank PF00023.25 KFO98305.1 - 7e-07 28.7 0.0 0.00037 20.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFO98305.1 - 2.9e-06 27.5 0.0 4.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO98305.1 - 7.3e-06 26.3 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO98305.1 - 0.00013 21.9 0.1 0.028 14.6 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KFO98305.1 - 0.0004 20.5 0.0 0.041 14.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DHDPS PF00701.17 KFO98306.1 - 2.4e-55 187.2 0.0 2.6e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MORN PF02493.15 KFO98307.1 - 7.8e-27 91.3 21.2 1.2e-08 34.1 0.3 5.5 6 0 0 6 6 6 4 MORN repeat HCBP_related PF06594.6 KFO98307.1 - 0.00011 21.7 0.2 0.064 12.8 0.0 3.1 3 0 0 3 3 3 2 Haemolysin-type calcium binding protein related domain PI3_PI4_kinase PF00454.22 KFO98308.1 - 1.5e-54 184.9 0.0 1.9e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MARVEL PF01284.18 KFO98309.1 - 2.5e-10 40.3 9.1 2.9e-10 40.1 6.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Herpes_LMP1 PF05297.6 KFO98309.1 - 4.3 6.1 5.7 5.1 5.9 4.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FYVE PF01363.16 KFO98310.1 - 2.3e-08 33.8 11.4 2.3e-08 33.8 7.9 2.2 3 0 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.11 KFO98310.1 - 9.6e-05 22.2 11.9 0.00011 22.1 5.3 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger Pex24p PF06398.6 KFO98310.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin IBR PF01485.16 KFO98310.1 - 0.73 9.7 12.8 0.11 12.3 4.0 2.9 3 0 0 3 3 3 0 IBR domain Erf4 PF10256.4 KFO98311.1 - 5.3e-33 113.3 0.0 6.2e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3920 PF13058.1 KFO98311.1 - 0.079 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) VCBS PF13517.1 KFO98312.1 - 1.4e-30 105.4 11.1 3.8e-11 43.1 0.9 5.0 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFO98312.1 - 2.4e-17 62.0 19.8 0.0001 21.8 0.2 5.7 5 0 0 5 5 5 4 FG-GAP repeat UnbV_ASPIC PF07593.7 KFO98312.1 - 1.4e-13 50.3 0.6 3.8e-13 48.9 0.1 2.0 2 0 0 2 2 2 1 ASPIC and UnbV EGF_CA PF07645.10 KFO98312.1 - 3.7e-11 42.8 6.9 3.7e-11 42.8 4.8 1.8 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 KFO98312.1 - 0.0014 18.2 9.5 0.18 11.4 1.8 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like TcdB_toxin_midN PF12256.3 KFO98312.1 - 0.14 11.5 3.9 5.1 6.5 0.0 3.8 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region DUF2414 PF10309.4 KFO98313.1 - 0.00093 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KFO98313.1 - 0.0011 18.9 0.1 0.0018 18.1 0.1 1.4 1 1 0 1 1 1 1 RNA binding domain SRCR PF00530.13 KFO98314.1 - 3.8e-86 283.7 26.0 9.6e-29 99.6 1.4 4.3 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFO98314.1 - 5.2e-18 65.0 11.8 4.9e-05 23.4 0.1 4.3 4 0 0 4 4 4 3 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.5 KFO98314.1 - 3.9e-07 30.2 0.9 0.0043 17.2 0.1 3.4 3 0 0 3 3 3 2 Hepsin, SRCR YecR PF13992.1 KFO98314.1 - 0.037 14.1 7.5 1.9 8.6 0.0 4.2 5 0 0 5 5 5 0 YecR-like lipoprotein CFEM PF05730.6 KFO98314.1 - 0.079 12.8 1.5 0.33 10.7 0.2 2.3 2 0 0 2 2 2 0 CFEM domain Mon1 PF03164.9 KFO98315.1 - 0.0042 15.7 0.0 2.1 6.8 0.0 2.5 2 0 0 2 2 2 2 Trafficking protein Mon1 Glyco_hydro_79n PF03662.9 KFO98316.1 - 3.8e-20 71.7 0.9 1.5e-19 69.8 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Aminotran_1_2 PF00155.16 KFO98318.1 - 2.6e-87 293.1 0.0 2.9e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Mito_carr PF00153.22 KFO98319.1 - 1.2e-42 143.5 1.6 1.8e-20 72.4 0.5 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein NDUF_B6 PF09782.4 KFO98319.1 - 0.051 13.4 0.5 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit UcrQ PF02939.11 KFO98319.1 - 0.1 12.3 1.1 0.23 11.2 0.2 2.0 2 0 0 2 2 2 0 UcrQ family GDA1_CD39 PF01150.12 KFO98320.1 - 3.7e-87 292.6 0.0 4.8e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ATP_synt_H PF05493.8 KFO98321.1 - 8.8e-29 99.3 2.4 1.1e-28 99.0 1.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit H ABC2_membrane_5 PF13346.1 KFO98321.1 - 0.063 12.5 1.5 0.061 12.6 1.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Far-17a_AIG1 PF04750.9 KFO98321.1 - 0.25 10.4 4.0 1.6 7.8 0.1 2.0 1 1 1 2 2 2 0 FAR-17a/AIG1-like protein SdpI PF13630.1 KFO98321.1 - 3.3 7.4 7.7 2.1 8.0 3.2 2.0 1 1 1 2 2 2 0 SdpI/YhfL protein family DUF1145 PF06611.7 KFO98321.1 - 5.3 6.7 7.0 4.3 7.0 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1145) COX15-CtaA PF02628.10 KFO98322.1 - 8.8e-84 280.9 5.6 9.9e-84 280.7 3.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein CutC PF03932.9 KFO98323.1 - 7.2e-59 198.4 0.0 1.4e-58 197.5 0.0 1.4 2 0 0 2 2 2 1 CutC family ABC_membrane PF00664.18 KFO98324.1 - 7.7e-75 251.8 36.0 2.1e-39 135.6 9.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFO98324.1 - 1.2e-50 171.3 2.8 3.3e-27 95.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 KFO98324.1 - 2e-08 33.7 7.2 0.0052 16.0 0.7 4.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFO98324.1 - 2.5e-08 34.1 0.5 0.011 15.6 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 KFO98324.1 - 2.5e-06 27.4 0.3 0.032 14.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KFO98324.1 - 6e-06 26.7 0.5 0.014 15.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 KFO98324.1 - 2.2e-05 24.6 1.9 6.9 6.5 0.1 4.8 3 2 1 4 4 3 0 AAA domain AAA_29 PF13555.1 KFO98324.1 - 3.2e-05 23.3 2.2 0.037 13.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ArgK PF03308.11 KFO98324.1 - 5.1e-05 22.1 1.7 0.0018 17.0 0.0 2.9 4 0 0 4 4 4 1 ArgK protein DUF258 PF03193.11 KFO98324.1 - 0.00022 20.4 1.1 0.46 9.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KFO98324.1 - 0.00037 20.0 5.1 0.028 13.8 0.1 3.4 3 1 1 4 4 4 1 AAA-like domain Zeta_toxin PF06414.7 KFO98324.1 - 0.0023 17.0 1.4 0.71 8.9 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.8 KFO98324.1 - 0.0028 16.6 0.4 1.3 7.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MobB PF03205.9 KFO98324.1 - 0.0031 17.2 1.5 2.5 7.7 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KFO98324.1 - 0.0034 16.8 0.0 0.13 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFO98324.1 - 0.0054 15.6 0.1 2.3 7.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KFO98324.1 - 0.0072 15.8 0.1 0.8 9.1 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 KFO98324.1 - 0.0074 16.1 9.1 0.093 12.5 0.2 3.1 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_17 PF13207.1 KFO98324.1 - 0.0075 17.0 0.0 12 6.7 0.0 3.3 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.4 KFO98324.1 - 0.0078 14.8 0.1 0.39 9.2 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_30 PF13604.1 KFO98324.1 - 0.014 15.0 1.4 2.6 7.6 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KFO98324.1 - 0.015 15.4 1.5 9.9 6.3 0.0 3.5 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KFO98324.1 - 0.027 14.2 9.2 0.088 12.6 0.4 2.8 3 0 0 3 3 2 0 Dynamin family ATP_bind_1 PF03029.12 KFO98324.1 - 0.033 13.7 1.2 1.4 8.3 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KFO98324.1 - 0.054 12.9 0.1 9.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KFO98324.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain BAR PF03114.13 KFO98325.1 - 2.3e-43 148.3 1.9 3.4e-43 147.8 1.3 1.2 1 0 0 1 1 1 1 BAR domain RhoGEF PF00621.15 KFO98325.1 - 1.2e-14 54.6 2.6 1.6e-14 54.2 0.0 2.3 2 1 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.12 KFO98325.1 - 2.5e-12 46.1 0.0 4e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 KFO98325.1 - 3.3e-12 45.7 0.1 1.9e-09 36.9 0.0 2.7 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFO98325.1 - 7.6e-12 44.4 0.0 8.2e-08 31.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.6 KFO98325.1 - 0.041 14.0 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial SH3 domain RhoGEF PF00621.15 KFO98326.1 - 2.5e-22 79.6 0.5 2.9e-22 79.4 0.4 1.0 1 0 0 1 1 1 1 RhoGEF domain GDA1_CD39 PF01150.12 KFO98327.1 - 4.4e-127 424.1 0.0 5.4e-127 423.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Neur_chan_LBD PF02931.18 KFO98328.1 - 1.9e-51 174.2 0.1 2.8e-51 173.7 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFO98328.1 - 3.4e-31 108.9 6.4 1.1e-28 100.7 1.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region UQ_con PF00179.21 KFO98329.1 - 3.1e-46 156.2 0.0 4.8e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFO98329.1 - 0.00057 19.6 0.0 0.00087 19.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFO98329.1 - 0.0019 18.1 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFO98329.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain Herpes_LMP2 PF07415.6 KFO98329.1 - 3.2 6.2 5.3 4.7 5.6 3.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Integrin_alpha2 PF08441.7 KFO98330.1 - 3e-81 273.6 5.4 1.1e-80 271.7 1.3 2.0 1 1 1 2 2 2 1 Integrin alpha FG-GAP PF01839.18 KFO98330.1 - 3.2e-18 64.8 6.4 1.7e-07 30.6 0.0 3.8 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.1 KFO98330.1 - 1.6e-11 44.3 6.7 3.5e-08 33.6 0.2 2.8 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 KFO98330.1 - 0.00088 18.8 0.5 0.0019 17.8 0.4 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region Rax2 PF12768.2 KFO98330.1 - 0.0096 15.1 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DAGK_cat PF00781.19 KFO98331.1 - 2.4e-18 65.8 0.0 5.1e-18 64.7 0.0 1.5 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain HLH PF00010.21 KFO98332.1 - 5.1e-16 58.1 1.1 5.1e-16 58.1 0.8 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Neuro_bHLH PF12533.3 KFO98332.1 - 4.4e-08 33.9 0.7 1e-07 32.7 0.1 1.9 2 0 0 2 2 2 1 Neuronal helix-loop-helix transcription factor YL1 PF05764.8 KFO98332.1 - 0.00068 19.3 19.1 0.00083 19.0 13.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.7 KFO98332.1 - 0.024 13.9 17.6 0.033 13.4 12.2 1.1 1 0 0 1 1 1 0 SDA1 DUF2890 PF11081.3 KFO98332.1 - 0.038 14.0 12.2 0.052 13.6 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop53 PF07767.6 KFO98332.1 - 0.081 11.8 19.7 0.1 11.5 13.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Vfa1 PF08432.5 KFO98332.1 - 0.17 11.8 12.6 0.22 11.5 8.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 KFO98332.1 - 0.3 9.5 17.4 0.33 9.3 12.0 1.1 1 0 0 1 1 1 0 Daxx Family Merozoite_SPAM PF07133.6 KFO98332.1 - 0.37 10.6 25.6 0.52 10.1 17.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Drc1-Sld2 PF11719.3 KFO98332.1 - 0.5 9.4 13.2 0.67 8.9 9.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein RRN3 PF05327.6 KFO98332.1 - 0.53 8.3 8.0 0.61 8.1 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 APG6 PF04111.7 KFO98332.1 - 0.58 9.1 10.7 0.71 8.8 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC45 PF02724.9 KFO98332.1 - 2 6.3 20.7 2.5 6.0 14.4 1.0 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.6 KFO98332.1 - 2.8 7.0 15.1 3.5 6.6 10.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RNase_H2-Ydr279 PF09468.5 KFO98332.1 - 2.8 7.0 7.7 3.5 6.7 5.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ycf1 PF05758.7 KFO98332.1 - 3.8 5.1 7.9 4 5.0 5.5 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 KFO98332.1 - 4.5 6.6 13.6 6 6.2 9.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO HSP90 PF00183.13 KFO98332.1 - 5.2 5.3 19.2 6.9 4.9 13.3 1.2 1 0 0 1 1 1 0 Hsp90 protein SSFA2_C PF14723.1 KFO98333.1 - 2.8e-79 265.0 8.4 2.8e-79 265.0 5.8 2.1 2 0 0 2 2 2 1 Sperm-specific antigen 2 C-terminus KRAP_IP3R_bind PF14722.1 KFO98333.1 - 1.5e-68 229.4 1.0 1.5e-68 229.4 0.7 2.6 2 0 0 2 2 2 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain DARPP-32 PF05395.7 KFO98334.1 - 3e-24 86.1 3.2 5.5e-24 85.2 2.2 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 PDEase_I PF00233.14 KFO98335.1 - 1.4e-98 329.3 11.1 2.4e-98 328.5 7.0 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 KFO98335.1 - 4.8e-27 93.6 0.0 1.2e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal FAA_hydrolase_N PF09298.6 KFO98335.1 - 0.014 15.4 0.5 0.049 13.6 0.2 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal Thioredoxin PF00085.15 KFO98336.1 - 1.3e-94 310.7 0.0 7.2e-25 86.6 0.0 6.0 6 0 0 6 6 6 4 Thioredoxin DnaJ PF00226.26 KFO98336.1 - 1.3e-22 79.3 2.8 2.4e-22 78.4 2.0 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_8 PF13905.1 KFO98336.1 - 5.1e-19 68.1 1.1 0.0023 18.0 0.0 5.9 4 1 1 5 5 5 4 Thioredoxin-like Thioredoxin_2 PF13098.1 KFO98336.1 - 7.4e-17 61.5 3.5 0.0029 17.7 0.0 6.5 4 3 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_6 PF13848.1 KFO98336.1 - 9.2e-16 58.1 0.0 1.3e-05 25.0 0.0 3.9 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFO98336.1 - 2.3e-12 46.7 3.5 0.032 14.2 0.1 4.6 4 0 0 4 4 4 3 Thioredoxin-like Redoxin PF08534.5 KFO98336.1 - 2e-08 33.8 3.7 0.055 13.0 0.0 4.2 4 0 0 4 4 4 3 Redoxin AhpC-TSA PF00578.16 KFO98336.1 - 9.1e-08 31.8 1.9 0.62 9.7 0.0 4.7 4 0 0 4 4 4 3 AhpC/TSA family Thioredoxin_9 PF14595.1 KFO98336.1 - 2.2e-05 24.0 0.3 2.8 7.5 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_3 PF13192.1 KFO98336.1 - 0.0076 16.0 0.0 2.3 8.0 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Calsequestrin PF01216.12 KFO98336.1 - 0.014 14.1 0.0 3.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Calsequestrin RMMBL PF07521.7 KFO98336.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase DUF3228 PF11539.3 KFO98336.1 - 0.068 12.2 0.0 1.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3228) Thioredoxin_4 PF13462.1 KFO98336.1 - 0.12 12.3 0.9 8 6.4 0.0 3.6 3 1 1 4 4 4 0 Thioredoxin TraF PF13728.1 KFO98336.1 - 0.13 11.6 0.1 1.8 8.0 0.0 2.7 3 0 0 3 3 3 0 F plasmid transfer operon protein PIP5K PF01504.13 KFO98337.1 - 3.6e-66 222.8 0.2 8.5e-66 221.6 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KFO98337.1 - 1.6e-33 116.1 0.2 3e-33 115.2 0.2 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KFO98337.1 - 2.7e-16 59.2 14.1 2.7e-16 59.2 9.8 2.2 2 0 0 2 2 2 1 FYVE zinc finger DEP PF00610.16 KFO98337.1 - 0.00043 19.9 0.0 0.0015 18.1 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Iso_dh PF00180.15 KFO98338.1 - 2.2e-60 204.4 0.0 5.7e-51 173.4 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.3 KFO98338.1 - 0.081 12.9 0.4 2.1 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) DUF4521 PF15021.1 KFO98339.1 - 0.084 12.4 1.0 0.1 12.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Shugoshin_C PF07557.6 KFO98339.1 - 0.67 9.4 5.2 0.19 11.2 1.3 1.9 2 0 0 2 2 2 0 Shugoshin C terminus CDC14 PF08045.6 KFO98341.1 - 0.02 13.9 6.4 0.77 8.8 0.1 3.1 3 0 0 3 3 3 0 Cell division control protein 14, SIN component p450 PF00067.17 KFO98343.1 - 2.4e-44 151.6 0.1 3.4e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UPF0139 PF03669.8 KFO98343.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) RA PF00788.18 KFO98344.1 - 1.3e-13 51.2 2.5 3.6e-13 49.8 0.1 2.7 2 1 1 3 3 3 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFO98344.1 - 7e-09 35.8 0.1 2.1e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 PH domain FERM_N PF09379.5 KFO98344.1 - 0.0032 17.4 0.2 0.0095 15.9 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain V-set PF07686.12 KFO98345.1 - 0.00027 20.8 0.3 0.00041 20.2 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFO98345.1 - 0.065 13.3 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Immunoglobulin domain PsbJ PF01788.12 KFO98345.1 - 0.11 12.0 0.6 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 PsbJ V-set PF07686.12 KFO98346.1 - 3.8e-09 36.4 0.1 5.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gE PF02480.11 KFO98346.1 - 0.0042 15.4 0.1 0.023 12.9 0.0 1.8 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Ig_3 PF13927.1 KFO98346.1 - 0.0067 16.9 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain stn_TNFRSF12A PF12191.3 KFO98346.1 - 0.0085 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain I-set PF07679.11 KFO98346.1 - 0.081 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain PAS_3 PF08447.6 KFO98348.1 - 8.4e-20 70.6 0.1 7.6e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KFO98348.1 - 2.9e-15 56.1 0.0 1.4e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFO98348.1 - 5.1e-10 39.1 0.0 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold HLH PF00010.21 KFO98348.1 - 3.2e-07 29.9 0.0 1.6e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFO98348.1 - 1.2e-05 25.5 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFO98348.1 - 0.0081 16.1 0.0 0.047 13.7 0.0 2.2 2 1 0 2 2 2 1 PAS fold Lipase_GDSL_2 PF13472.1 KFO98349.1 - 9.7e-06 25.8 0.0 2.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cadherin PF00028.12 KFO98350.1 - 3.4e-83 274.0 5.0 3.3e-19 68.9 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFO98350.1 - 1.2e-55 187.6 2.2 2.4e-55 186.6 1.6 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFO98350.1 - 2.9e-05 23.5 0.0 0.13 11.8 0.0 3.8 4 0 0 4 4 4 2 Cadherin-like ASFV_J13L PF05568.6 KFO98350.1 - 0.041 13.4 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Sigma_1s PF02454.11 KFO98350.1 - 0.051 13.3 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Sigma 1s protein DUF443 PF04276.7 KFO98350.1 - 0.055 12.9 0.3 0.085 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF912 PF06024.7 KFO98350.1 - 0.07 13.1 0.5 0.16 12.0 0.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Y_Y_Y PF07495.8 KFO98350.1 - 0.089 12.5 0.0 23 4.8 0.0 3.8 4 0 0 4 4 4 0 Y_Y_Y domain TMEM154 PF15102.1 KFO98350.1 - 0.091 12.4 0.2 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 KFO98350.1 - 0.17 11.4 0.3 0.28 10.7 0.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family IncA PF04156.9 KFO98350.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 IncA protein Cadherin PF00028.12 KFO98351.1 - 4.7e-79 260.7 5.2 3.1e-19 69.0 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFO98351.1 - 3.6e-56 189.3 0.8 1.1e-55 187.7 0.5 1.8 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFO98351.1 - 0.005 16.3 0.0 1.5 8.3 0.0 3.8 4 1 0 4 4 4 1 Cadherin-like Cadherin_pro PF08758.6 KFO98351.1 - 0.023 14.4 0.0 23 4.8 0.0 3.6 3 0 0 3 3 3 0 Cadherin prodomain like ASFV_J13L PF05568.6 KFO98351.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Yae1_N PF09811.4 KFO98353.1 - 4.5e-21 74.0 73.8 1.5e+04 -22.1 51.1 5.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Cadherin PF00028.12 KFO98354.1 - 1.6e-80 265.4 7.0 3.1e-19 69.0 0.1 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFO98354.1 - 3.7e-54 182.8 0.4 8.6e-54 181.6 0.3 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFO98354.1 - 0.00011 21.6 0.0 0.73 9.4 0.0 3.7 4 1 0 4 4 4 2 Cadherin-like ASFV_J13L PF05568.6 KFO98354.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein HCO3_cotransp PF00955.16 KFO98355.1 - 4.9e-133 444.4 7.7 5.4e-133 444.3 5.3 1.0 1 0 0 1 1 1 1 HCO3- transporter family ArfGap PF01412.13 KFO98356.1 - 2.9e-38 130.2 0.0 5.6e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Miro PF08477.8 KFO98356.1 - 6.3e-22 78.3 0.0 1.2e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFO98356.1 - 4e-17 62.0 0.0 1.3e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 Ras family Ank_2 PF12796.2 KFO98356.1 - 4.4e-12 46.1 0.0 8.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PH PF00169.24 KFO98356.1 - 1.9e-09 37.6 0.1 1.7e-08 34.6 0.0 2.5 2 1 0 2 2 2 1 PH domain Ank_4 PF13637.1 KFO98356.1 - 1.5e-07 31.7 0.0 6.2e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KFO98356.1 - 2.2e-07 30.3 0.2 0.0025 17.5 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFO98356.1 - 0.00061 19.9 0.6 0.034 14.3 0.1 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) PH_6 PF15406.1 KFO98356.1 - 0.004 17.1 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFO98356.1 - 0.026 14.7 0.0 0.7 10.1 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Ank_3 PF13606.1 KFO98356.1 - 0.036 14.2 0.0 1 9.8 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat DUF1830 PF08865.6 KFO98356.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Ank_2 PF12796.2 KFO98357.1 - 7.2e-47 157.6 6.3 6.2e-15 55.3 0.3 3.7 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFO98357.1 - 2.8e-42 140.4 18.0 2.9e-07 29.9 0.2 8.6 8 1 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KFO98357.1 - 8.4e-34 115.3 5.2 9.3e-08 32.3 0.0 8.0 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO98357.1 - 1.1e-29 101.7 12.6 1.8e-10 40.7 0.3 5.6 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO98357.1 - 1e-28 96.5 11.3 6e-05 22.9 0.1 8.6 9 0 0 9 9 9 7 Ankyrin repeat SOCS_box PF07525.11 KFO98357.1 - 4.9e-10 39.0 6.5 1.1e-09 37.9 4.5 1.6 1 0 0 1 1 1 1 SOCS box ScdA_N PF04405.9 KFO98357.1 - 0.11 11.9 1.8 3.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) ABC_tran PF00005.22 KFO98358.1 - 3.5e-47 160.1 0.0 1.4e-24 86.9 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KFO98358.1 - 1.7e-20 72.6 3.7 1.7e-20 72.6 2.6 3.2 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 KFO98358.1 - 1.2e-17 64.8 0.4 4.9e-06 26.7 0.0 4.2 3 1 0 4 4 4 3 AAA domain AAA_29 PF13555.1 KFO98358.1 - 1.1e-06 28.0 0.4 0.00091 18.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KFO98358.1 - 3.2e-06 27.9 0.4 0.014 16.2 0.0 3.1 3 1 0 3 3 2 2 AAA domain SMC_N PF02463.14 KFO98358.1 - 3.5e-06 26.4 0.6 0.99 8.5 0.0 3.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 KFO98358.1 - 3.4e-05 24.3 0.0 0.47 10.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KFO98358.1 - 4.6e-05 23.4 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KFO98358.1 - 5.5e-05 22.3 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFO98358.1 - 0.00021 21.2 0.0 0.07 13.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KFO98358.1 - 0.00024 21.0 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.1 KFO98358.1 - 0.00055 19.1 3.1 0.31 10.0 0.0 3.4 3 2 2 5 5 5 2 AAA ATPase domain AAA_23 PF13476.1 KFO98358.1 - 0.0009 19.6 9.0 0.025 14.9 0.0 3.5 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 KFO98358.1 - 0.0013 18.4 0.3 0.35 10.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KFO98358.1 - 0.0028 17.7 0.1 0.68 10.0 0.1 3.0 2 1 0 2 2 2 1 AAA domain Rop PF01815.11 KFO98358.1 - 0.0034 16.7 3.1 0.44 10.0 0.1 2.9 2 0 0 2 2 2 1 Rop protein AAA_14 PF13173.1 KFO98358.1 - 0.0039 17.0 0.0 0.88 9.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 KFO98358.1 - 0.0067 16.3 0.1 0.17 11.7 0.0 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KFO98358.1 - 0.0092 15.9 0.0 0.46 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFO98358.1 - 0.01 16.1 0.9 0.17 12.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KFO98358.1 - 0.015 15.5 0.1 1.5 9.0 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KFO98358.1 - 0.018 14.4 0.3 1.9 7.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFO98358.1 - 0.029 13.8 3.5 0.091 12.1 0.0 3.0 4 0 0 4 4 4 0 AAA-like domain NB-ARC PF00931.17 KFO98358.1 - 0.033 13.0 0.0 4.6 6.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KFO98358.1 - 0.051 13.7 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 KFO98358.1 - 0.051 12.3 3.0 3.3 6.4 0.0 2.8 3 0 0 3 3 3 0 ArgK protein AAA_5 PF07728.9 KFO98358.1 - 0.054 13.2 0.2 4.9 6.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 KFO98358.1 - 0.058 13.2 0.0 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 Dynamin family MobB PF03205.9 KFO98358.1 - 0.059 13.0 0.3 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KFO98358.1 - 0.071 12.1 0.0 0.22 10.6 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin CHGN PF05679.11 KFO98359.1 - 1.4e-145 485.8 0.0 1.7e-145 485.5 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 KFO98359.1 - 3.3e-10 39.6 0.1 6.2e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 Fringe-like DUF2387 PF09526.5 KFO98360.1 - 0.064 13.1 0.1 0.064 13.1 0.1 1.1 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) SWIB PF02201.13 KFO98361.1 - 2.4e-25 87.9 0.1 6.4e-25 86.6 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain CSD PF00313.17 KFO98362.1 - 5.6e-28 96.5 0.6 8.2e-28 95.9 0.4 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KFO98362.1 - 0.0036 16.7 0.0 0.0091 15.4 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease B OB domain Synaptonemal_3 PF15191.1 KFO98363.1 - 8.1e-33 112.0 6.4 8.8e-33 111.9 4.4 1.0 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 CENP-F_leu_zip PF10473.4 KFO98363.1 - 0.021 14.6 3.5 0.028 14.2 2.4 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BAR PF03114.13 KFO98363.1 - 0.033 13.7 0.8 0.037 13.5 0.6 1.1 1 0 0 1 1 1 0 BAR domain CbiA PF01656.18 KFO98363.1 - 0.068 12.5 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Lyase_8_N PF08124.6 KFO98363.1 - 0.1 11.4 0.5 0.12 11.2 0.4 1.0 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Med9 PF07544.8 KFO98363.1 - 0.12 12.1 1.4 7.7 6.3 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF972 PF06156.8 KFO98363.1 - 0.16 12.3 1.3 0.24 11.7 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Pkinase_Tyr PF07714.12 KFO98364.1 - 3.8e-63 212.9 0.0 5.8e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO98364.1 - 8.1e-31 107.1 0.0 1.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KFO98364.1 - 0.00099 18.1 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TMEM154 PF15102.1 KFO98364.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family 7tm_1 PF00001.16 KFO98364.1 - 0.083 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Atg8 PF02991.11 KFO98365.1 - 9.8e-40 134.7 0.0 1.1e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFO98365.1 - 1.4e-08 34.7 0.0 1.5e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 TMEM52 PF14979.1 KFO98366.1 - 5.3e-60 201.7 1.1 6.2e-60 201.5 0.7 1.0 1 0 0 1 1 1 1 Transmembrane 52 DUF4131 PF13567.1 KFO98366.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Corona_S2 PF01601.11 KFO98366.1 - 0.053 11.6 4.4 0.065 11.3 3.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PIRT PF15099.1 KFO98366.1 - 0.15 11.2 0.2 0.31 10.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family WBP-1 PF11669.3 KFO98366.1 - 0.16 12.0 6.5 0.28 11.2 4.5 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 Herpes_LMP2 PF07415.6 KFO98366.1 - 0.28 9.7 3.0 0.24 9.9 0.9 1.6 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Prominin PF05478.6 KFO98366.1 - 0.54 7.7 3.2 0.68 7.3 2.3 1.1 1 0 0 1 1 1 0 Prominin DUF3481 PF11980.3 KFO98366.1 - 4.6 7.1 6.0 6.2 6.7 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3481) Lectin_C PF00059.16 KFO98367.1 - 6e-14 52.5 2.2 6e-14 52.5 1.5 2.2 3 0 0 3 3 3 1 Lectin C-type domain VirB8 PF04335.8 KFO98367.1 - 0.3 10.6 1.2 0.45 10.0 0.8 1.2 1 0 0 1 1 1 0 VirB8 protein Herpes_UL45 PF05473.7 KFO98367.1 - 3.8 6.8 7.4 35 3.7 5.2 2.2 1 1 0 1 1 1 0 UL45 protein Cys_knot PF00007.17 KFO98368.1 - 1.9e-31 108.2 14.6 2.1e-31 108.0 10.1 1.0 1 0 0 1 1 1 1 Cystine-knot domain SCP-1 PF05483.7 KFO98369.1 - 3.7e-208 693.0 157.1 1.1e-206 688.1 108.9 2.4 1 1 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) Fzo_mitofusin PF04799.8 KFO98369.1 - 0.0037 16.6 6.6 0.0037 16.6 4.6 7.6 3 2 6 9 9 9 1 fzo-like conserved region Hormone_recep PF00104.25 KFO98370.1 - 3.8e-30 104.5 0.4 6.7e-30 103.7 0.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO98370.1 - 3.9e-29 100.6 13.3 3.9e-29 100.6 9.2 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) CSD PF00313.17 KFO98371.1 - 4.3e-79 260.2 15.8 1.8e-16 59.6 0.1 8.2 8 0 0 8 8 8 5 'Cold-shock' DNA-binding domain SUZ-C PF12901.2 KFO98371.1 - 4.7e-14 51.6 0.2 9.9e-14 50.5 0.1 1.6 1 0 0 1 1 1 1 SUZ-C motif S1-like PF14444.1 KFO98371.1 - 4.5e-13 48.6 10.0 0.024 14.3 0.0 6.8 7 0 0 7 7 7 4 S1-like CusF_Ec PF11604.3 KFO98371.1 - 6.8e-07 29.0 7.5 0.38 10.6 0.0 6.6 8 0 0 8 8 8 2 Copper binding periplasmic protein CusF Antitoxin-MazE PF04014.13 KFO98371.1 - 0.024 14.3 6.6 9.9 6.0 0.0 5.3 5 0 0 5 5 5 0 Antidote-toxin recognition MazE LMWSLP_N PF12211.3 KFO98371.1 - 0.068 13.0 5.9 12 5.6 0.0 4.7 5 1 1 6 6 6 0 Low molecular weight S layer protein N terminal Herpes_Helicase PF02689.9 KFO98371.1 - 0.12 10.0 0.0 0.25 9.0 0.0 1.4 1 0 0 1 1 1 0 Helicase OB_RNB PF08206.6 KFO98371.1 - 0.31 10.5 10.2 18 4.9 0.0 5.1 4 0 0 4 4 4 0 Ribonuclease B OB domain Ras PF00071.17 KFO98372.1 - 6.5e-58 194.6 0.1 7.5e-58 194.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98372.1 - 1.3e-19 70.8 0.0 1.8e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO98372.1 - 6.7e-09 35.2 0.0 8.1e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO98372.1 - 4.7e-08 32.6 0.1 2.9e-07 30.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFO98372.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFO98372.1 - 0.00076 18.7 0.1 0.0054 16.0 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.4 KFO98372.1 - 0.027 13.4 0.0 1.2 8.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Gtr1_RagA PF04670.7 KFO98372.1 - 0.029 13.5 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 KFO98372.1 - 0.029 13.7 0.0 0.066 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFO98372.1 - 0.04 14.7 0.8 13 6.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFO98372.1 - 0.051 13.7 0.1 1.1 9.4 0.1 2.5 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 KFO98372.1 - 0.064 12.4 0.2 0.082 12.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 KFO98372.1 - 0.079 11.9 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Septin Ldh_1_N PF00056.18 KFO98372.1 - 0.11 12.3 0.1 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain AAA_14 PF13173.1 KFO98372.1 - 0.13 12.1 0.2 0.28 11.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KFO98372.1 - 0.16 11.5 0.7 3.8 6.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein A_deaminase PF00962.17 KFO98373.1 - 4.1e-119 397.3 0.6 6.4e-119 396.7 0.4 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DENN PF02141.16 KFO98374.1 - 1.7e-59 200.6 1.1 1.7e-59 200.6 0.8 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 KFO98374.1 - 2.6e-21 75.3 1.1 5.1e-21 74.4 0.8 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFO98374.1 - 1.5e-18 66.5 2.8 4.3e-18 65.1 1.9 1.8 1 0 0 1 1 1 1 dDENN domain BCAS2 PF05700.6 KFO98375.1 - 4.1e-53 180.1 17.8 4.7e-53 179.9 12.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) THOC7 PF05615.8 KFO98375.1 - 9.2e-06 25.9 11.2 1.5e-05 25.2 2.8 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 EzrA PF06160.7 KFO98375.1 - 0.00061 18.0 7.5 0.0036 15.5 5.2 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Filament PF00038.16 KFO98375.1 - 0.0016 17.9 11.0 0.0019 17.7 7.4 1.3 1 1 0 1 1 1 1 Intermediate filament protein DUF4201 PF13870.1 KFO98375.1 - 0.012 15.0 9.1 0.12 11.7 4.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DivIC PF04977.10 KFO98375.1 - 0.027 13.9 7.3 0.79 9.2 0.8 2.6 2 0 0 2 2 2 0 Septum formation initiator GAS PF13851.1 KFO98375.1 - 0.037 13.2 11.8 0.03 13.5 7.1 1.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phlebovirus_NSM PF07246.6 KFO98375.1 - 0.084 12.0 5.8 0.11 11.6 4.0 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CENP-F_leu_zip PF10473.4 KFO98375.1 - 0.097 12.5 10.2 0.16 11.8 6.8 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GvpK PF05121.7 KFO98375.1 - 0.2 11.4 7.0 1 9.2 0.3 2.9 1 1 1 2 2 2 0 Gas vesicle protein K Ribosomal_L29 PF00831.18 KFO98375.1 - 0.22 11.2 6.3 0.55 9.9 1.4 2.3 2 0 0 2 2 2 0 Ribosomal L29 protein DUF2508 PF10704.4 KFO98375.1 - 0.25 11.5 3.8 0.13 12.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) TPR_MLP1_2 PF07926.7 KFO98375.1 - 0.26 11.0 14.3 2.2 8.0 9.9 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 KFO98375.1 - 0.36 10.7 8.1 0.48 10.3 0.3 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) XkdW PF09636.5 KFO98375.1 - 0.38 10.6 5.9 0.32 10.9 1.3 2.3 1 1 0 2 2 2 0 XkdW protein Seryl_tRNA_N PF02403.17 KFO98375.1 - 0.52 10.3 6.3 0.35 10.9 2.7 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.9 KFO98375.1 - 0.52 9.9 10.1 3.3 7.2 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Syntaxin PF00804.20 KFO98375.1 - 0.63 10.2 6.3 1.5 9.0 4.4 1.6 1 0 0 1 1 1 0 Syntaxin TMF_DNA_bd PF12329.3 KFO98375.1 - 0.73 9.6 10.2 0.25 11.1 4.6 2.0 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.8 KFO98375.1 - 0.88 9.5 6.7 35 4.4 0.1 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Spc24 PF08286.6 KFO98375.1 - 0.88 9.2 10.3 1.8 8.3 0.6 2.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF3450 PF11932.3 KFO98375.1 - 1 8.6 13.1 0.074 12.3 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Med9 PF07544.8 KFO98375.1 - 1.4 8.7 9.1 1.4 8.7 0.6 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FliJ PF02050.11 KFO98375.1 - 1.5 8.8 16.3 12 5.9 0.1 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein CENP-H PF05837.7 KFO98375.1 - 1.5 9.0 12.8 0.48 10.6 5.7 2.3 2 2 0 2 2 2 0 Centromere protein H (CENP-H) DUF2203 PF09969.4 KFO98375.1 - 1.6 8.9 5.6 1.8 8.8 2.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Tup_N PF08581.5 KFO98375.1 - 1.6 8.9 12.6 0.87 9.8 2.1 3.2 1 1 2 3 3 3 0 Tup N-terminal DUF4140 PF13600.1 KFO98375.1 - 1.6 9.2 5.9 2.8 8.4 0.5 2.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.1 KFO98375.1 - 1.8 8.5 10.7 7.7 6.4 1.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Pox_A_type_inc PF04508.7 KFO98375.1 - 2.3 8.2 6.5 2 8.4 0.1 3.2 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat Syntaxin-6_N PF09177.6 KFO98375.1 - 2.5 8.5 7.3 7.2 7.0 3.2 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HR1 PF02185.11 KFO98375.1 - 3.7 7.3 8.9 1.3 8.7 2.2 2.5 2 1 0 2 2 2 0 Hr1 repeat DUF2443 PF10398.4 KFO98375.1 - 4.7 7.0 5.9 4.5 7.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) FlxA PF14282.1 KFO98375.1 - 4.7 7.2 16.4 5 7.1 9.6 2.3 1 1 0 1 1 1 0 FlxA-like protein MerR-DNA-bind PF09278.6 KFO98375.1 - 5.5 7.4 6.3 3.3 8.1 0.3 2.9 2 1 1 3 3 3 0 MerR, DNA binding bZIP_1 PF00170.16 KFO98375.1 - 5.7 6.9 7.3 10 6.1 0.1 2.9 3 0 0 3 3 2 0 bZIP transcription factor TMF_TATA_bd PF12325.3 KFO98375.1 - 8.9 6.0 13.3 18 5.0 5.5 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Bromodomain PF00439.20 KFO98376.1 - 4e-23 81.1 0.4 2.8e-22 78.4 0.2 2.4 2 0 0 2 2 2 1 Bromodomain zf-B_box PF00643.19 KFO98376.1 - 7e-12 45.0 20.5 7.4e-09 35.3 5.1 5.0 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.24 KFO98376.1 - 1.7e-08 33.9 9.6 1.7e-08 33.9 6.7 4.5 4 0 0 4 4 4 1 PHD-finger SpoIISB_antitox PF14185.1 KFO98376.1 - 0.024 14.3 1.5 0.065 12.9 0.6 2.1 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system C2 PF00168.25 KFO98377.1 - 6.6e-57 189.3 0.0 8.9e-27 92.7 0.0 3.2 3 0 0 3 3 3 3 C2 domain CEP76-C2 PF15627.1 KFO98377.1 - 0.00027 20.4 0.1 0.036 13.5 0.0 2.9 3 0 0 3 3 3 1 CEP76 C2 domain T2SM PF04612.7 KFO98377.1 - 0.1 12.3 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF1049 PF06305.6 KFO98377.1 - 0.32 10.5 2.4 0.7 9.4 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 KFO98378.1 - 8.5e-53 179.1 0.0 1.4e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98378.1 - 2.7e-24 85.6 0.0 4.4e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO98378.1 - 7.8e-06 25.0 0.0 6.7e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO98378.1 - 0.0053 16.5 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFO98378.1 - 0.0095 14.7 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KFO98378.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DRMBL PF07522.9 KFO98379.1 - 3.3e-15 56.0 0.0 6.9e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFO98379.1 - 5.6e-12 45.6 0.2 3.2e-11 43.1 0.2 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFO98379.1 - 6.2e-05 22.7 1.1 0.00016 21.4 0.8 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KFO98379.1 - 0.0087 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Adaptin_N PF01602.15 KFO98380.1 - 8.6e-35 120.0 0.0 9.5e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KFO98380.1 - 0.0058 16.8 0.1 0.24 11.6 0.0 3.1 3 2 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KFO98380.1 - 0.0077 16.2 3.1 2.9 8.2 0.0 4.6 4 1 1 5 5 5 1 HEAT repeat Phtf-FEM1B_bdg PF12129.3 KFO98382.1 - 2.8e-62 208.7 2.8 6.5e-62 207.5 2.0 1.7 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor PDZ PF00595.19 KFO98383.1 - 9.2e-64 211.6 7.4 2.2e-15 56.6 0.3 5.4 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO98383.1 - 1.3e-26 92.2 0.1 8.9e-05 22.3 0.1 5.4 5 0 0 5 5 5 5 PDZ domain WW PF00397.21 KFO98383.1 - 2.7e-16 59.0 4.7 3.1e-09 36.5 0.1 2.5 2 0 0 2 2 2 2 WW domain Guanylate_kin PF00625.16 KFO98383.1 - 1.3e-10 41.0 0.0 2.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.1 KFO98383.1 - 2.7e-05 23.8 5.1 0.66 9.7 0.1 4.8 5 0 0 5 5 5 2 Tricorn protease PDZ domain MFS_1 PF07690.11 KFO98384.1 - 1.1e-29 103.2 32.8 1.4e-22 79.8 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFO98384.1 - 0.00083 18.0 9.5 0.00083 18.0 6.6 3.5 2 1 3 5 5 5 1 Sugar (and other) transporter MFS_1_like PF12832.2 KFO98384.1 - 0.0029 17.3 7.0 0.038 13.7 2.1 3.5 3 1 1 4 4 4 1 MFS_1 like family DUF1077 PF06417.7 KFO98384.1 - 4.3 6.6 5.5 12 5.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1077) TAFA PF12020.3 KFO98385.1 - 2.4e-40 136.5 7.5 2.9e-40 136.2 5.2 1.1 1 0 0 1 1 1 1 TAFA family PP2C PF00481.16 KFO98386.1 - 7.6e-28 97.5 0.0 6e-13 48.7 0.0 3.0 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.7 KFO98386.1 - 9e-06 25.5 0.0 0.006 16.2 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Ras PF00071.17 KFO98387.1 - 3.6e-58 195.5 0.0 4.2e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98387.1 - 1.3e-16 61.1 0.0 1.8e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO98387.1 - 2.1e-10 40.1 0.0 3.6e-10 39.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO98387.1 - 3.1e-05 23.4 0.0 8.2e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFO98387.1 - 0.013 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFO98387.1 - 0.035 13.3 0.0 0.058 12.6 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_12 PF13087.1 KFO98388.1 - 6.6e-47 159.4 0.0 1.1e-46 158.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFO98388.1 - 5.9e-29 101.3 0.0 2.5e-13 50.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KFO98388.1 - 5.8e-09 35.8 0.0 8.5e-08 32.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFO98388.1 - 5e-08 32.5 0.0 7.4e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KFO98388.1 - 0.0003 20.6 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 KFO98388.1 - 0.0052 16.9 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 KFO98388.1 - 0.012 14.6 0.0 0.71 8.7 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.1 KFO98388.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD_C PF13361.1 KFO98388.1 - 0.018 14.5 0.2 6.2 6.1 0.0 2.8 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain HOOK PF05622.7 KFO98388.1 - 0.063 11.0 0.0 0.09 10.5 0.0 1.1 1 0 0 1 1 1 0 HOOK protein AAA_24 PF13479.1 KFO98388.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 KFO98388.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain F-actin_cap_A PF01267.12 KFO98389.1 - 2.1e-102 341.7 0.4 2.4e-102 341.6 0.3 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ST7 PF04184.7 KFO98390.1 - 2.6e-301 999.5 2.2 2.9e-301 999.4 1.6 1.0 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.1 KFO98390.1 - 0.00056 20.1 0.5 0.0025 18.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFO98390.1 - 0.033 14.1 4.0 1.5 8.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Clathrin PF00637.15 KFO98390.1 - 0.034 13.7 0.2 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_1 PF00515.23 KFO98390.1 - 0.057 13.0 3.6 8.9 6.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFO98390.1 - 0.17 12.6 5.9 0.89 10.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFO98390.1 - 1 9.0 8.5 19 4.9 0.0 4.0 3 1 2 5 5 5 0 TPR repeat TPR_19 PF14559.1 KFO98390.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat wnt PF00110.14 KFO98391.1 - 8.2e-124 412.8 28.7 9.3e-124 412.6 19.9 1.0 1 0 0 1 1 1 1 wnt family CortBP2 PF09727.4 KFO98392.1 - 1.3e-57 194.4 18.2 1.3e-57 194.4 12.6 2.2 1 1 1 2 2 2 1 Cortactin-binding protein-2 DUF4200 PF13863.1 KFO98392.1 - 0.073 13.0 42.1 0.061 13.2 10.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 KFO98392.1 - 1.1 7.5 21.6 1.9 6.8 15.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4164 PF13747.1 KFO98392.1 - 2.6 8.2 29.1 0.45 10.6 7.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) BTB_2 PF02214.17 KFO98393.1 - 3.1e-29 101.0 0.1 6.8e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 KFO98393.1 - 2.3e-22 79.2 14.3 3.7e-22 78.5 8.7 2.0 2 0 0 2 2 2 1 Ion transport protein Shal-type PF11601.3 KFO98393.1 - 4.3e-16 58.0 13.9 7e-16 57.4 9.6 1.3 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels PKD_channel PF08016.7 KFO98393.1 - 0.13 10.7 11.5 0.25 9.6 8.0 1.6 1 1 0 1 1 1 0 Polycystin cation channel Ion_trans_2 PF07885.11 KFO98393.1 - 2.7 7.7 15.7 0.045 13.4 3.0 2.7 3 0 0 3 3 3 0 Ion channel DUF3399 PF11879.3 KFO98394.1 - 5.9e-47 158.1 12.4 5.9e-47 158.1 8.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans_2 PF07885.11 KFO98394.1 - 0.0013 18.4 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 Ion channel DEAD PF00270.24 KFO98395.1 - 1.9e-28 99.0 0.0 3.8e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO98395.1 - 6e-21 74.1 0.0 1.5e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFO98395.1 - 7.9e-05 22.3 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KFO98395.1 - 0.00023 21.0 0.0 0.00066 19.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFO98395.1 - 0.045 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFO98395.1 - 0.054 13.6 0.0 0.2 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFO98395.1 - 0.062 13.5 0.1 0.53 10.4 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CMS1 PF14617.1 KFO98395.1 - 0.2 10.6 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FAM212 PF15342.1 KFO98396.1 - 1.4e-29 101.4 0.5 5.8e-29 99.4 0.4 2.1 1 0 0 1 1 1 1 FAM212 family DUF1639 PF07797.9 KFO98396.1 - 0.016 14.5 0.4 0.23 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) Ras PF00071.17 KFO98397.1 - 3.4e-53 179.3 0.3 3.7e-53 179.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98397.1 - 4.5e-21 75.5 0.1 5.7e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO98397.1 - 3.9e-09 35.9 0.1 4.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO98397.1 - 1.3e-05 24.7 0.2 3.2e-05 23.4 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFO98397.1 - 6.3e-05 22.9 0.0 8.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFO98397.1 - 0.00094 17.9 0.0 0.17 10.5 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit AAA_22 PF13401.1 KFO98397.1 - 0.036 14.2 0.2 1.1 9.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain 7tm_1 PF00001.16 KFO98398.1 - 1.1e-47 162.3 16.3 1.3e-47 162.1 11.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO98398.1 - 3e-11 42.9 16.8 3.5e-11 42.7 11.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Pmp3 PF01679.12 KFO98398.1 - 0.85 9.3 9.8 0.33 10.7 3.1 2.5 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Mt_ATP-synt_B PF05405.9 KFO98399.1 - 2.6e-50 170.0 11.3 2.9e-50 169.8 7.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) EF-hand_7 PF13499.1 KFO98401.1 - 6.3e-24 83.8 10.9 7.5e-13 48.4 0.2 3.4 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KFO98401.1 - 1.2e-20 71.1 14.6 7e-06 24.9 0.2 5.0 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.1 KFO98401.1 - 1.9e-18 64.6 7.5 4.6e-05 22.9 0.0 5.0 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 KFO98401.1 - 7.7e-17 60.6 3.2 2.6e-09 36.5 0.3 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFO98401.1 - 5.3e-13 47.6 8.4 3.9e-05 22.7 0.8 4.4 4 1 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 KFO98401.1 - 4.9e-08 32.9 0.4 6.9e-05 22.8 0.0 2.8 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFO98401.1 - 1.2e-05 24.9 3.0 0.31 10.8 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand VCBS PF13517.1 KFO98401.1 - 0.01 16.1 0.1 3.5 8.0 0.0 3.0 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFO98401.1 - 1.7 8.4 7.8 5.8 6.7 0.1 3.2 3 0 0 3 3 3 0 FG-GAP repeat EF-hand_7 PF13499.1 KFO98402.1 - 2.7e-31 107.5 8.1 2e-14 53.4 0.0 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFO98402.1 - 9.9e-23 77.6 10.7 7e-07 28.1 0.2 4.3 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KFO98402.1 - 6e-19 66.1 5.4 8.6e-05 22.1 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFO98402.1 - 1.9e-16 59.4 2.1 9.2e-09 34.7 0.0 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFO98402.1 - 8.1e-16 56.5 9.6 1.3e-05 24.3 0.1 4.0 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 KFO98402.1 - 2.9e-07 30.4 0.2 0.019 15.0 0.0 3.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFO98402.1 - 0.0025 17.5 1.8 1.8 8.3 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF3408 PF11888.3 KFO98402.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Rab5-bind PF09311.6 KFO98403.1 - 0.00017 21.5 31.6 0.00017 21.5 21.9 2.8 1 1 1 2 2 1 1 Rabaptin-like protein RNA_pol_Rpc4 PF05132.9 KFO98403.1 - 0.0059 16.5 0.8 0.0059 16.5 0.5 2.9 4 0 0 4 4 4 1 RNA polymerase III RPC4 DUF948 PF06103.6 KFO98403.1 - 0.063 13.1 5.7 0.049 13.4 1.0 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) rve_3 PF13683.1 KFO98403.1 - 0.22 11.0 0.1 0.22 11.0 0.1 3.4 4 1 0 4 4 4 0 Integrase core domain Reo_sigmaC PF04582.7 KFO98403.1 - 0.58 9.2 8.8 0.55 9.3 4.4 1.9 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Phage_int_SAM_2 PF12834.2 KFO98403.1 - 1.2 9.6 12.2 3.2 8.1 3.0 3.4 3 0 0 3 3 3 0 Phage integrase, N-terminal DUF3416 PF11896.3 KFO98403.1 - 3.6 7.4 13.7 0.2 11.6 3.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3416) PEARLI-4 PF05278.7 KFO98403.1 - 4.7 6.5 30.0 0.45 9.8 5.6 3.2 3 0 0 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) DDE_Tnp_IS66 PF03050.9 KFO98403.1 - 5.8 6.0 21.7 0.31 10.2 5.4 2.5 1 1 1 2 2 2 0 Transposase IS66 family ATG16 PF08614.6 KFO98403.1 - 5.9 6.6 54.1 4.5 7.0 24.9 3.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 KFO98403.1 - 6.6 6.4 18.3 1.5 8.5 7.3 3.0 1 1 1 2 2 2 0 Laminin Domain II adh_short PF00106.20 KFO98404.1 - 1e-25 90.6 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFO98404.1 - 1.1e-09 38.1 0.1 2.9e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFO98404.1 - 1e-08 35.2 0.0 1.4e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFO98404.1 - 5.3e-06 25.7 0.0 7.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KFO98404.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SE PF08491.5 KFO98404.1 - 0.071 11.9 0.1 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_10 PF13460.1 KFO98404.1 - 0.098 12.6 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KFO98405.1 - 3.6e-28 98.5 0.1 4.9e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFO98405.1 - 8.9e-11 42.0 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFO98405.1 - 3.6e-09 36.5 1.4 1.8e-08 34.2 1.0 1.9 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFO98405.1 - 2.7e-05 23.4 0.0 4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 KFO98405.1 - 6.3e-05 23.0 0.2 0.00012 22.1 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KFO98405.1 - 0.0072 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KFO98405.1 - 0.0096 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FMO-like PF00743.14 KFO98405.1 - 0.029 12.5 0.0 0.051 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_10 PF13460.1 KFO98405.1 - 0.06 13.3 0.1 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 KFO98405.1 - 0.062 13.1 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFO98405.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFO98405.1 - 0.077 12.6 0.4 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain G0-G1_switch_2 PF15103.1 KFO98406.1 - 1e-35 122.0 0.1 1.1e-35 121.8 0.1 1.0 1 0 0 1 1 1 1 G0/G1 switch protein 2 HILPDA PF15220.1 KFO98406.1 - 0.087 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated DUF3955 PF13127.1 KFO98406.1 - 0.11 12.0 0.2 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) Laminin_N PF00055.12 KFO98407.1 - 3.4e-41 140.7 0.0 3.4e-41 140.7 0.0 2.6 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFO98407.1 - 3.6e-33 113.2 112.9 3.4e-11 42.8 9.3 7.1 6 2 1 7 7 7 5 Laminin EGF-like (Domains III and V) DUF948 PF06103.6 KFO98407.1 - 0.0039 17.0 10.4 1 9.2 0.2 5.1 4 1 0 4 4 4 2 Bacterial protein of unknown function (DUF948) F5_F8_type_C PF00754.20 KFO98407.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain DUF1664 PF07889.7 KFO98407.1 - 0.073 12.8 14.1 4 7.2 0.4 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 KFO98407.1 - 0.88 7.3 16.9 0.58 7.9 4.8 3.1 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 KFO98407.1 - 1.1 7.6 17.3 0.91 7.9 5.2 2.6 2 1 1 3 3 3 0 AAA domain Laminin_II PF06009.7 KFO98407.1 - 8.2 6.1 27.0 0.43 10.3 0.2 5.4 3 2 3 6 6 6 0 Laminin Domain II Tropomyosin_1 PF12718.2 KFO98407.1 - 9.9 6.0 32.8 0.52 10.1 4.1 5.5 3 2 3 6 6 6 0 Tropomyosin like Pkinase PF00069.20 KFO98408.1 - 5e-78 261.8 0.0 6.3e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98408.1 - 7.4e-36 123.5 0.0 9.4e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO98408.1 - 1.3e-09 37.4 0.0 2.4e-07 30.0 0.0 2.1 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KFO98408.1 - 2.3e-05 24.2 0.0 0.11 12.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFO98408.1 - 0.0002 20.5 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFO98408.1 - 0.00061 19.1 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 KFO98408.1 - 0.0046 16.3 0.1 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Sema PF01403.14 KFO98409.1 - 2.6e-81 273.3 0.0 3e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Sema domain Plexin_cytopl PF08337.7 KFO98410.1 - 3.7e-255 847.3 0.3 4.5e-255 847.0 0.2 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 KFO98410.1 - 5.4e-38 128.8 10.6 3.2e-10 39.8 0.0 5.6 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.20 KFO98410.1 - 3.5e-22 78.3 59.0 9.1e-11 41.7 9.7 3.5 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.14 KFO98410.1 - 6.4e-06 25.9 0.2 0.0033 17.0 0.2 2.3 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase IncA PF04156.9 KFO98410.1 - 0.0016 18.0 0.4 0.0016 18.0 0.3 1.8 2 0 0 2 2 2 1 IncA protein EphA2_TM PF14575.1 KFO98410.1 - 0.034 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF948 PF06103.6 KFO98410.1 - 0.17 11.7 0.4 0.46 10.3 0.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RhoGEF PF00621.15 KFO98411.1 - 4.5e-39 134.1 5.6 4.5e-39 134.1 3.9 3.4 2 1 0 2 2 2 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 KFO98411.1 - 2.3e-14 53.5 0.0 1e-13 51.4 0.0 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Spectrin PF00435.16 KFO98411.1 - 3.6e-09 36.8 14.1 3.3e-05 24.0 0.0 4.7 3 1 1 4 4 4 2 Spectrin repeat PH PF00169.24 KFO98411.1 - 5.9e-07 29.6 0.1 1.5e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 PH domain ARL2_Bind_BART PF11527.3 KFO98411.1 - 0.94 9.2 9.4 5.3 6.8 0.6 3.2 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART HAD PF12710.2 KFO98412.1 - 4.8e-19 69.2 0.0 1.3e-18 67.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFO98412.1 - 7.4e-19 67.6 0.9 5.6e-18 64.8 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KFO98412.1 - 3.1e-14 53.8 0.8 2.9e-10 40.9 0.4 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFO98412.1 - 1.1e-11 44.5 0.2 8.2e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFO98412.1 - 0.0005 19.7 0.1 0.075 12.6 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Spc97_Spc98 PF04130.8 KFO98413.1 - 2.1e-126 422.4 7.3 3.3e-126 421.7 5.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3519 PF12033.3 KFO98413.1 - 0.099 12.8 0.3 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) AAA_33 PF13671.1 KFO98414.1 - 2.7e-20 72.6 0.0 4.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFO98414.1 - 1.6e-06 27.3 0.0 4.5e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin SPRY PF00622.23 KFO98414.1 - 2.8e-06 27.4 0.0 0.00013 22.0 0.0 2.9 3 0 0 3 3 3 1 SPRY domain AAA_18 PF13238.1 KFO98414.1 - 0.0056 16.9 0.0 0.043 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KFO98414.1 - 0.19 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 7tm_4 PF13853.1 KFO98415.1 - 7.7e-58 194.3 11.2 8.7e-58 194.2 7.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFO98415.1 - 0.0001 21.5 6.3 0.00012 21.3 4.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.1 KFO98415.1 - 0.099 12.5 0.6 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Dymeclin PF09742.4 KFO98416.1 - 4.1e-10 38.4 0.1 4.2e-10 38.3 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein COesterase PF00135.23 KFO98417.1 - 5.1e-52 177.2 0.0 5.6e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Clat_adaptor_s PF01217.15 KFO98418.1 - 9.6e-38 129.1 0.3 1e-37 128.9 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CortBP2 PF09727.4 KFO98419.1 - 6.7e-70 234.5 22.6 6.7e-70 234.5 15.7 7.0 3 2 4 7 7 7 2 Cortactin-binding protein-2 DUF3596 PF12167.3 KFO98419.1 - 0.058 12.9 0.2 0.29 10.6 0.2 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Reo_sigmaC PF04582.7 KFO98419.1 - 1.2 8.2 27.9 0.11 11.6 2.0 4.3 2 2 2 4 4 4 0 Reovirus sigma C capsid protein CDC50 PF03381.10 KFO98420.1 - 1.6e-98 329.2 0.3 1.8e-98 329.1 0.2 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family fn3 PF00041.16 KFO98421.1 - 1.7e-253 819.6 87.1 7.3e-17 61.2 0.8 18.4 18 0 0 18 18 18 18 Fibronectin type III domain VWA PF00092.23 KFO98421.1 - 3.4e-197 649.0 15.4 2.7e-50 170.5 0.3 4.3 4 0 0 4 4 4 4 von Willebrand factor type A domain VWA_2 PF13519.1 KFO98421.1 - 2.4e-51 174.2 1.6 1.3e-12 48.1 0.1 4.4 4 0 0 4 4 4 4 von Willebrand factor type A domain Collagen PF01391.13 KFO98421.1 - 7.1e-34 115.1 174.4 2.9e-08 33.1 21.6 5.5 2 2 3 5 5 5 5 Collagen triple helix repeat (20 copies) Interfer-bind PF09294.5 KFO98421.1 - 1.8e-24 85.8 0.9 0.2 11.7 0.0 15.5 16 1 1 17 17 17 3 Interferon-alpha/beta receptor, fibronectin type III vWA-TerF-like PF10138.4 KFO98421.1 - 1.5e-08 34.7 4.6 0.024 14.4 0.4 3.9 5 0 0 5 5 5 3 vWA found in TerF C terminus DUF2369 PF10179.4 KFO98421.1 - 0.00011 21.4 1.4 14 4.6 0.0 8.2 12 0 0 12 12 12 0 Uncharacterised conserved protein (DUF2369) SusE PF14292.1 KFO98421.1 - 0.00013 21.7 5.9 15 5.4 0.0 8.1 12 0 0 12 12 12 0 SusE outer membrane protein CBM_4_9 PF02018.12 KFO98421.1 - 0.0045 16.9 4.4 1.7 8.6 0.1 4.6 5 0 0 5 5 4 2 Carbohydrate binding domain Toxin_R_bind_N PF07953.7 KFO98421.1 - 0.01 15.3 0.2 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding ThiI PF02568.9 KFO98421.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) A2M_comp PF07678.9 KFO98422.1 - 2.7e-70 236.4 0.2 5.6e-70 235.3 0.0 1.6 2 0 0 2 2 2 1 A-macroglobulin complement component A2M PF00207.17 KFO98422.1 - 6.8e-28 96.0 0.8 4.7e-27 93.3 0.5 2.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 KFO98422.1 - 5.4e-25 87.7 11.4 1.6e-23 82.9 0.2 4.9 6 0 0 6 6 6 2 Alpha-2-macroglobulin family N-terminal region A2M_N PF01835.14 KFO98422.1 - 3e-20 72.2 0.0 7.3e-18 64.6 0.0 3.7 3 0 0 3 3 3 1 MG2 domain A2M_recep PF07677.9 KFO98422.1 - 9.2e-20 70.6 0.6 2.7e-19 69.1 0.1 2.2 2 0 0 2 2 2 1 A-macroglobulin receptor Thiol-ester_cl PF10569.4 KFO98422.1 - 2.7e-19 68.0 0.7 6.1e-19 66.9 0.5 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 KFO98422.1 - 5.6e-07 29.9 1.0 0.15 12.4 0.1 4.8 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFO98422.1 - 0.018 15.0 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 Prenyltransferase-like MFS_1 PF07690.11 KFO98423.1 - 2.2e-58 197.6 32.0 3.6e-57 193.6 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFO98423.1 - 1.9e-07 30.0 23.8 2.5e-06 26.3 16.5 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter GTP_EFTU PF00009.22 KFO98424.1 - 1.1e-56 191.2 0.0 1.6e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFO98424.1 - 2.6e-36 123.7 0.0 7.6e-36 122.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFO98424.1 - 1.6e-17 63.4 1.0 1.6e-17 63.4 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KFO98424.1 - 3e-05 23.5 0.2 9.3e-05 21.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KFO98424.1 - 0.00068 19.5 0.4 0.002 18.0 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFO98424.1 - 0.048 13.4 0.1 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family Pkinase PF00069.20 KFO98425.1 - 5.6e-50 169.9 0.0 6.4e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98425.1 - 3.3e-21 75.5 0.0 4e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO98425.1 - 0.00093 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFO98425.1 - 0.0088 15.7 0.3 0.026 14.2 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFO98425.1 - 0.2 10.4 0.2 0.26 10.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase 6PF2K PF01591.13 KFO98426.1 - 4.2e-30 104.4 0.1 4.7e-30 104.3 0.1 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFO98426.1 - 0.00018 21.6 0.1 0.00045 20.3 0.1 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Baculo_PEP_N PF04512.7 KFO98426.1 - 0.093 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus RVT_1 PF00078.22 KFO98427.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KFO98428.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.12 KFO98430.1 - 9.6e-103 336.6 1.5 1.7e-22 79.4 0.0 7.3 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 KFO98430.1 - 9.8e-81 270.6 1.2 1.6e-80 269.9 0.9 1.4 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 KFO98430.1 - 7.7e-14 51.0 0.0 6.6e-06 25.6 0.0 4.6 4 0 0 4 4 4 2 Cadherin-like BACON PF13004.2 KFO98430.1 - 0.00058 20.0 5.9 1.9 8.8 0.3 5.3 4 1 1 5 5 5 2 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Mid2 PF04478.7 KFO98430.1 - 0.0027 17.1 0.1 0.007 15.7 0.1 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3827 PF12877.2 KFO98430.1 - 0.0078 14.3 0.0 0.012 13.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) TMEM154 PF15102.1 KFO98430.1 - 0.033 13.9 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.13 KFO98430.1 - 0.033 13.9 0.2 0.099 12.4 0.0 1.9 2 0 0 2 2 2 0 Glycophorin A Adeno_E3_CR2 PF02439.10 KFO98430.1 - 0.13 11.7 1.6 0.33 10.5 1.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SAM_2 PF07647.12 KFO98431.1 - 5.8e-12 45.2 0.1 1.5e-11 43.9 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFO98431.1 - 2.4e-06 27.6 0.1 7.4e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4446 PF14584.1 KFO98431.1 - 0.37 10.6 6.3 0.054 13.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.14 KFO98431.1 - 7.1 4.3 11.7 12 3.5 8.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RabGAP-TBC PF00566.13 KFO98432.1 - 1.2e-14 54.2 8.2 7.2e-12 45.2 2.2 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain 7tm_1 PF00001.16 KFO98433.1 - 2.7e-68 229.9 14.9 3.8e-68 229.4 10.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CholecysA-Rec_N PF09193.5 KFO98433.1 - 2.5e-24 84.8 0.2 5.3e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 Cholecystokinin A receptor, N-terminal 7TM_GPCR_Srsx PF10320.4 KFO98433.1 - 4.8e-08 32.4 23.6 3.2e-07 29.7 16.4 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Brr6_like_C_C PF10104.4 KFO98433.1 - 1.6 8.2 9.7 0.16 11.4 1.5 3.0 2 2 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain BTD PF09270.5 KFO98434.1 - 2.8e-65 218.8 0.0 4.2e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 KFO98434.1 - 3.4e-56 189.6 0.8 6.3e-56 188.7 0.5 1.5 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.19 KFO98434.1 - 1.9e-08 34.1 0.9 1.4e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ig_2 PF13895.1 KFO98434.1 - 0.055 13.6 0.1 0.47 10.6 0.0 2.5 3 0 0 3 3 3 0 Immunoglobulin domain Sel1 PF08238.7 KFO98436.1 - 4.9e-15 55.5 38.2 0.001 19.6 0.4 9.7 10 0 0 10 10 10 6 Sel1 repeat TPR_16 PF13432.1 KFO98436.1 - 0.0081 16.8 4.9 0.36 11.5 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat Na_Pi_cotrans PF02690.10 KFO98437.1 - 4.4e-56 188.5 28.5 3.5e-30 104.5 6.0 2.6 2 1 1 3 3 3 2 Na+/Pi-cotransporter DUF2244 PF10003.4 KFO98437.1 - 1.7 8.0 5.5 8 5.8 3.8 2.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) PI3_PI4_kinase PF00454.22 KFO98438.1 - 1.4e-58 198.1 0.0 1.8e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SLA_LP_auto_ag PF05889.8 KFO98439.1 - 4e-179 595.0 0.0 4.7e-179 594.8 0.0 1.0 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 KFO98439.1 - 3.2e-05 23.2 0.0 4.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 KFO98439.1 - 0.0031 16.0 0.1 0.085 11.2 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain EPTP PF03736.12 KFO98440.1 - 1.1e-93 306.7 23.0 7e-15 54.5 0.1 7.3 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 KFO98440.1 - 1.8e-23 82.0 7.8 2.2e-13 49.7 1.0 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFO98440.1 - 1.3e-11 43.8 2.5 1.4e-05 24.5 0.1 2.8 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO98440.1 - 5.7e-10 37.8 5.0 0.23 11.6 0.1 5.1 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_5 PF13306.1 KFO98440.1 - 4.1e-08 32.9 0.0 2.1e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO98440.1 - 0.0012 18.6 4.3 1.7 9.1 0.1 4.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_9 PF14580.1 KFO98440.1 - 0.076 12.5 0.1 0.23 10.9 0.0 1.7 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.1 KFO98440.1 - 4.6 7.6 7.5 94 3.5 0.0 4.3 3 1 1 4 4 4 0 Leucine Rich repeat DUF2353 PF09789.4 KFO98441.1 - 7.6e-90 301.3 19.2 1.1e-89 300.8 13.3 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF869 PF05911.6 KFO98441.1 - 0.0011 17.3 3.6 0.0011 17.3 2.5 3.4 2 1 2 4 4 4 2 Plant protein of unknown function (DUF869) KLRAQ PF10205.4 KFO98441.1 - 0.0023 17.9 11.0 0.075 13.0 2.9 3.8 2 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein THP2 PF09432.5 KFO98441.1 - 0.0063 16.3 3.7 0.016 15.0 2.6 1.6 1 0 0 1 1 1 1 Tho complex subunit THP2 IncA PF04156.9 KFO98441.1 - 0.012 15.1 12.3 0.012 15.1 8.5 3.8 2 1 2 4 4 4 0 IncA protein DivIVA PF05103.8 KFO98441.1 - 0.031 14.3 14.7 0.25 11.3 2.4 3.5 3 0 0 3 3 3 0 DivIVA protein TSC22 PF01166.13 KFO98441.1 - 0.04 13.8 19.0 0.18 11.7 0.1 5.0 5 0 0 5 5 5 0 TSC-22/dip/bun family DUF3972 PF13118.1 KFO98441.1 - 0.17 11.9 6.4 9.3 6.3 0.2 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) Ufd2P_core PF10408.4 KFO98441.1 - 0.2 9.8 4.2 0.078 11.2 0.8 1.7 1 1 1 2 2 2 0 Ubiquitin elongating factor core DUF4140 PF13600.1 KFO98441.1 - 0.26 11.7 21.3 2.4 8.6 0.6 5.1 5 0 0 5 5 5 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 KFO98441.1 - 0.27 10.8 19.3 0.1 12.2 1.9 3.1 2 2 0 3 3 3 0 Mnd1 family CorA PF01544.13 KFO98441.1 - 0.5 9.3 13.7 0.04 12.9 4.6 2.2 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein COG2 PF06148.6 KFO98441.1 - 1.2 8.9 10.6 0.92 9.3 0.4 3.3 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 KFO98441.1 - 1.7 8.6 20.7 1.3 9.0 2.1 4.3 3 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 KFO98441.1 - 1.9 6.8 17.2 0.1 11.0 0.9 2.9 1 1 2 4 4 4 0 Protein of unknown function (DUF342) Cep57_MT_bd PF06657.8 KFO98441.1 - 1.9 8.4 16.3 4.1 7.4 0.1 4.8 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 GAS PF13851.1 KFO98441.1 - 2.1 7.5 27.0 0.13 11.4 2.8 3.6 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 KFO98441.1 - 2.1 8.1 30.2 0.04 13.7 4.3 3.5 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 KFO98441.1 - 2.3 7.9 15.5 3.7 7.3 0.7 4.2 1 1 3 5 5 5 0 Laminin Domain II HAP1_N PF04849.8 KFO98441.1 - 2.9 6.7 27.9 0.16 10.9 7.7 3.6 3 1 1 4 4 4 0 HAP1 N-terminal conserved region DUF3461 PF11944.3 KFO98441.1 - 3.5 7.4 7.5 8.6 6.2 0.1 2.8 3 1 0 3 3 2 0 Protein of unknown function (DUF3461) DUF4164 PF13747.1 KFO98441.1 - 4.3 7.5 17.2 4.5 7.4 0.4 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.4 KFO98441.1 - 4.9 7.0 31.7 0.34 10.7 2.6 4.5 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phlebovirus_NSM PF07246.6 KFO98441.1 - 5.4 6.0 9.2 7.8 5.5 0.6 2.8 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Lebercilin PF15619.1 KFO98441.1 - 5.6 6.3 29.0 4.3 6.7 15.3 3.3 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4482 PF14818.1 KFO98441.1 - 6 7.5 23.1 1.2 9.7 1.4 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4482) Myb_DNA-bind_5 PF13873.1 KFO98441.1 - 8 6.4 7.6 34 4.4 0.1 3.5 4 0 0 4 4 3 0 Myb/SANT-like DNA-binding domain DUF4463 PF14703.1 KFO98441.1 - 10 6.7 9.8 35 4.9 0.1 3.3 3 1 0 3 3 2 0 Domain of unknown function (DUF4463) Sod_Cu PF00080.15 KFO98442.1 - 8.8e-33 113.4 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HA2 PF04408.18 KFO98443.1 - 8.8e-27 93.1 0.3 2.3e-26 91.7 0.2 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFO98443.1 - 2.9e-25 88.3 0.1 5.2e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFO98443.1 - 4.1e-12 45.7 0.0 1.9e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFO98443.1 - 7.4e-07 28.8 0.2 2.6e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFO98443.1 - 7.3e-05 22.9 0.0 0.00035 20.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFO98443.1 - 0.0017 18.2 0.0 0.87 9.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SRP54 PF00448.17 KFO98443.1 - 0.0031 16.9 0.0 0.0099 15.3 0.0 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KFO98443.1 - 0.0034 16.8 0.0 0.0073 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFO98443.1 - 0.009 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KFO98443.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 KFO98443.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.1 KFO98443.1 - 0.026 14.1 0.0 0.054 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KFO98443.1 - 0.064 12.1 0.0 0.18 10.7 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein HTH_IclR PF09339.5 KFO98443.1 - 0.068 12.7 0.1 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain RRM_1 PF00076.17 KFO98444.1 - 1.3e-07 31.1 0.0 2.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98444.1 - 1.7e-05 24.6 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO98444.1 - 0.0099 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tox-ODYAM1 PF15642.1 KFO98444.1 - 0.19 10.3 1.6 0.43 9.2 1.1 1.5 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Yae1_N PF09811.4 KFO98445.1 - 8e-12 44.4 35.4 0.011 15.2 2.7 3.6 2 1 0 2 2 2 2 Essential protein Yae1, N terminal GDI PF00996.13 KFO98446.1 - 0.21 9.8 0.0 0.35 9.1 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Cofilin_ADF PF00241.15 KFO98447.1 - 5.8e-12 45.5 0.0 7.9e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.1 KFO98447.1 - 6.6e-09 35.2 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFO98447.1 - 1.9e-07 30.3 0.7 3.8e-07 29.3 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFO98447.1 - 0.0002 20.7 0.0 0.00045 19.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M14 PF00246.19 KFO98448.1 - 2e-69 234.3 0.0 2.7e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.20 KFO98448.1 - 4.2e-25 88.0 0.1 6.6e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain CarboxypepD_reg PF13620.1 KFO98448.1 - 3.3e-12 46.2 0.0 5.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFO98448.1 - 0.00057 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) phage_tail_N PF08400.5 KFO98448.1 - 0.032 13.9 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 Prophage tail fibre N-terminal DNA_pol_E_B PF04042.11 KFO98449.1 - 1.6e-45 154.9 0.0 2.5e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CS PF04969.11 KFO98451.1 - 6.9e-17 61.7 1.9 2.2e-16 60.1 0.1 2.5 3 0 0 3 3 3 1 CS domain zf-C4H2 PF10146.4 KFO98451.1 - 0.039 13.9 0.4 0.039 13.9 0.3 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein PHO4 PF01384.15 KFO98452.1 - 1.1e-131 438.3 0.9 1.4e-131 438.0 0.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family AIF-MLS PF14962.1 KFO98452.1 - 0.04 13.5 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondria Localisation Sequence 5_nucleotid PF05761.9 KFO98453.1 - 7.3e-175 581.7 0.2 8.2e-175 581.6 0.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family NIF PF03031.13 KFO98453.1 - 0.036 13.7 0.1 0.72 9.4 0.0 2.5 3 0 0 3 3 3 0 NLI interacting factor-like phosphatase E1_dh PF00676.15 KFO98454.1 - 2.2e-92 308.9 0.0 3e-92 308.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 KFO98454.1 - 1.2e-67 226.8 0.0 1.9e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF4343 PF14243.1 KFO98454.1 - 0.091 12.6 0.1 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) zf-MIZ PF02891.15 KFO98455.1 - 1.4e-22 78.9 4.7 1.4e-22 78.9 3.3 2.2 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFO98455.1 - 4.6e-05 22.8 1.1 4.6e-05 22.8 0.7 2.2 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit Pro_isomerase PF00160.16 KFO98456.1 - 5.8e-38 130.5 0.4 6.4e-38 130.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Laminin_EGF PF00053.19 KFO98459.1 - 9.6e-21 73.4 149.5 0.00026 20.8 5.9 10.0 3 2 7 10 10 10 9 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFO98459.1 - 0.00044 20.3 6.6 0.00044 20.3 4.6 15.5 11 5 2 13 13 13 6 EGF-like domain hEGF PF12661.2 KFO98459.1 - 0.012 15.6 1.2 0.012 15.6 0.8 16.2 17 0 0 17 17 17 0 Human growth factor-like EGF IP_trans PF02121.13 KFO98460.1 - 8.1e-137 454.3 2.7 9.9e-137 454.1 1.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Exo_endo_phos PF03372.18 KFO98461.1 - 9.7e-24 84.6 0.1 1.5e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CALCOCO1 PF07888.6 KFO98461.1 - 5.6e-10 38.1 0.5 8.6e-10 37.5 0.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Myosin_head PF00063.16 KFO98462.1 - 6.2e-238 791.3 4.6 1.2e-237 790.4 3.2 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFO98462.1 - 1.1e-37 129.3 2.3 1.8e-37 128.5 1.6 1.4 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 KFO98462.1 - 7.3e-05 22.0 14.5 0.0032 16.9 0.7 3.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KFO98462.1 - 0.0023 18.0 0.1 0.015 15.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KFO98462.1 - 0.0086 15.1 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KFO98462.1 - 0.042 14.6 0.0 0.19 12.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain 14-3-3 PF00244.15 KFO98463.1 - 5.2e-108 359.5 0.4 5.8e-108 359.4 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein SH3_2 PF07653.12 KFO98464.1 - 2.9e-24 84.2 3.6 5.4e-12 45.0 0.0 3.1 3 1 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 KFO98464.1 - 1.7e-17 62.5 4.8 4e-15 54.9 0.2 2.6 3 0 0 3 3 3 2 SH3 domain SH2 PF00017.19 KFO98464.1 - 5.1e-17 61.4 0.0 1.2e-16 60.3 0.0 1.6 1 1 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 KFO98464.1 - 7.3e-15 54.2 0.6 1e-10 41.0 0.1 3.2 4 0 0 4 4 4 2 Variant SH3 domain DUF2414 PF10309.4 KFO98465.1 - 4e-23 80.8 0.0 9.1e-23 79.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KFO98465.1 - 2.5e-05 24.1 0.0 6.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain T2SK PF03934.8 KFO98466.1 - 0.00016 20.9 0.3 0.00082 18.6 0.0 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K LRR_4 PF12799.2 KFO98466.1 - 0.0017 17.9 0.6 0.0088 15.6 0.2 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFO98466.1 - 0.0034 17.3 0.6 0.19 11.8 0.1 3.3 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 KFO98466.1 - 0.012 15.5 0.9 1.4 9.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 KFO98466.1 - 0.036 14.2 0.3 0.27 11.5 0.2 2.6 1 0 0 1 1 1 0 Leucine rich repeat UCH PF00443.24 KFO98466.1 - 0.054 12.6 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TMEM219 PF14940.1 KFO98467.1 - 1.9e-96 321.4 1.2 2.3e-96 321.1 0.8 1.1 1 0 0 1 1 1 1 Transmembrane 219 VPS9 PF02204.13 KFO98468.1 - 2.3e-30 104.6 0.0 7.2e-30 103.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-A20 PF01754.11 KFO98468.1 - 4.7e-12 45.2 5.3 9.6e-12 44.2 3.7 1.6 1 0 0 1 1 1 1 A20-like zinc finger DUF501 PF04417.7 KFO98468.1 - 0.041 13.7 3.8 2.7 7.8 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF501) BTB_2 PF02214.17 KFO98469.1 - 8.7e-20 70.7 0.0 5.3e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Sulfotransfer_3 PF13469.1 KFO98470.1 - 2.4e-14 54.5 0.1 3.6e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 KFO98470.1 - 1.8e-08 34.0 0.1 1.6e-07 30.8 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain RNA_pol_Rpb4 PF03874.11 KFO98471.1 - 1.1e-09 38.3 0.4 1.2e-09 38.2 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Lyase_1 PF00206.15 KFO98472.1 - 1.7e-103 346.1 0.0 4e-103 344.8 0.0 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.1 KFO98472.1 - 5.7e-22 77.5 0.0 1.8e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Glyco_hydro_2_C PF02836.12 KFO98473.1 - 9.6e-102 339.8 0.0 1.2e-101 339.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KFO98473.1 - 8.4e-32 110.0 0.1 1.4e-31 109.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFO98473.1 - 4.3e-06 27.1 0.3 1.6e-05 25.3 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Cellulase-like PF12876.2 KFO98473.1 - 0.0025 18.2 0.0 0.0062 16.9 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like D-aminoacyl_C PF07908.7 KFO98473.1 - 0.28 10.5 1.1 1.3 8.4 0.2 2.4 2 1 0 2 2 2 0 D-aminoacylase, C-terminal region VKOR PF07884.9 KFO98474.1 - 5.5e-21 74.8 10.2 6.1e-21 74.7 7.1 1.0 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Claudin_2 PF13903.1 KFO98474.1 - 0.049 13.3 4.9 0.056 13.1 3.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Yip1 PF04893.12 KFO98474.1 - 4.2 6.8 13.9 7.2 6.0 9.7 1.4 1 1 0 1 1 1 0 Yip1 domain SPC25 PF06703.6 KFO98474.1 - 5.1 6.6 9.9 10 5.6 6.8 1.5 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2207 PF09972.4 KFO98474.1 - 5.6 5.4 7.0 6.3 5.2 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CHCH PF06747.8 KFO98475.1 - 5.1e-07 29.4 7.9 7.5e-07 28.9 5.5 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 KFO98475.1 - 0.0043 17.1 15.1 0.0082 16.2 10.5 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Keratin PF02422.11 KFO98475.1 - 0.23 11.4 2.7 0.41 10.6 1.9 1.4 1 0 0 1 1 1 0 Keratin Med3 PF11593.3 KFO98475.1 - 1.2 8.2 10.6 1.5 7.9 7.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 KFO98476.1 - 5.2e-77 258.4 0.0 6.4e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98476.1 - 1.1e-32 113.2 0.0 1.3e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO98476.1 - 3.3e-10 39.4 0.0 2.9e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 KFO98476.1 - 5.1e-07 28.9 0.2 2.8e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFO98476.1 - 2.4e-05 23.7 0.2 4.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFO98476.1 - 0.00016 21.4 0.1 0.17 11.5 0.2 2.8 2 2 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFO98476.1 - 0.0037 16.8 0.1 0.0058 16.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KFO98476.1 - 0.011 15.0 0.1 0.021 14.1 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Bac_DNA_binding PF00216.16 KFO98476.1 - 0.18 11.8 1.0 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Bacterial DNA-binding protein FGE-sulfatase PF03781.11 KFO98477.1 - 2.4e-79 266.3 4.3 2.8e-79 266.1 3.0 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Cpn60_TCP1 PF00118.19 KFO98478.1 - 3.2e-96 322.8 2.6 1.1e-63 215.5 0.0 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family HAD PF12710.2 KFO98479.1 - 2.8e-18 66.7 0.0 6e-18 65.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFO98479.1 - 4e-13 50.2 0.3 6e-12 46.4 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFO98479.1 - 4.6e-06 26.9 0.0 8.8e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFO98479.1 - 8.9e-06 25.2 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 KFO98479.1 - 1.5e-05 24.3 0.0 3.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Putative Phosphatase Acid_phosphat_B PF03767.9 KFO98479.1 - 0.0013 18.1 0.0 0.088 12.1 0.0 2.1 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.7 KFO98479.1 - 0.0039 16.8 0.1 0.18 11.3 0.0 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFO98479.1 - 0.008 15.8 0.0 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like StbA PF06406.6 KFO98479.1 - 0.026 13.4 0.0 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 StbA protein PFK PF00365.15 KFO98479.1 - 0.041 12.8 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase NIPSNAP PF07978.8 KFO98480.1 - 7.1e-38 128.6 0.8 1.4e-31 108.5 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP Ribosomal_S17 PF00366.15 KFO98481.1 - 1.1e-09 38.1 0.2 4.1e-09 36.3 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S17 FERM_C PF09380.5 KFO98482.1 - 1.7e-34 117.9 0.6 1.7e-34 117.9 0.4 2.4 3 0 0 3 3 3 1 FERM C-terminal PH-like domain ERM PF00769.14 KFO98482.1 - 5.4e-32 111.2 40.0 5.4e-32 111.2 27.7 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.13 KFO98482.1 - 3e-24 85.5 1.7 3e-24 85.5 1.2 2.8 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFO98482.1 - 4e-14 52.4 1.2 4.2e-13 49.1 0.1 3.2 3 0 0 3 3 3 1 FERM N-terminal domain IL8 PF00048.15 KFO98483.1 - 1.9e-07 30.9 0.2 2e-07 30.8 0.1 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 KFO98484.1 - 8.4e-17 60.8 2.6 9.1e-17 60.7 1.8 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Alpha_adaptinC2 PF02883.15 KFO98485.1 - 0.08 13.2 0.2 0.56 10.5 0.0 2.4 2 0 0 2 2 2 0 Adaptin C-terminal domain Rad51 PF08423.6 KFO98486.1 - 1e-19 70.4 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFO98486.1 - 2.3e-15 56.5 0.0 3.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFO98486.1 - 1.5e-10 40.6 0.0 2.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 KFO98486.1 - 1.4e-08 33.9 1.8 1e-06 27.8 1.3 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.24 KFO98486.1 - 0.00043 20.4 0.1 0.0018 18.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.16 KFO98486.1 - 0.00076 18.6 0.1 0.043 12.8 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KFO98486.1 - 0.0012 18.9 0.0 0.034 14.3 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_19 PF13245.1 KFO98486.1 - 0.0013 18.4 0.0 0.0037 16.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFO98486.1 - 0.0052 16.9 0.1 0.0099 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFO98486.1 - 0.031 13.6 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CobU PF02283.11 KFO98486.1 - 0.047 13.1 0.4 0.17 11.3 0.1 2.0 2 1 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase UPF0079 PF02367.12 KFO98486.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CbiA PF01656.18 KFO98486.1 - 0.12 11.8 0.1 0.33 10.3 0.1 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TrwB_AAD_bind PF10412.4 KFO98486.1 - 0.12 10.9 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 KFO98486.1 - 0.14 11.7 0.2 0.69 9.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain Isochorismatase PF00857.15 KFO98486.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 Isochorismatase family PAXNEB PF05625.6 KFO98486.1 - 0.23 10.2 1.1 2.7 6.7 0.1 2.1 2 0 0 2 2 2 0 PAXNEB protein UNC45-central PF11701.3 KFO98487.1 - 7.9e-51 171.8 9.6 4.9e-48 162.7 0.3 3.8 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central TPR_11 PF13414.1 KFO98487.1 - 1.7e-22 78.8 21.3 2.5e-15 55.8 5.6 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFO98487.1 - 4.3e-13 48.2 12.4 0.00014 21.2 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFO98487.1 - 7.9e-13 47.2 11.0 0.00077 19.2 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat HEAT_2 PF13646.1 KFO98487.1 - 7.2e-09 35.8 2.1 0.014 15.6 0.0 5.6 4 1 2 6 6 6 3 HEAT repeats Arm PF00514.18 KFO98487.1 - 2.2e-07 30.4 10.7 0.014 15.2 0.0 7.2 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat TPR_8 PF13181.1 KFO98487.1 - 2.3e-06 26.9 12.2 0.017 14.8 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFO98487.1 - 6.4e-06 26.0 8.6 0.00021 21.1 3.3 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFO98487.1 - 8.8e-06 25.4 2.3 0.00014 21.5 0.6 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO98487.1 - 0.00029 21.4 8.9 0.0024 18.5 2.9 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO98487.1 - 0.0003 20.8 7.8 0.0014 18.6 5.4 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFO98487.1 - 0.002 18.2 7.7 0.5 10.7 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO98487.1 - 0.014 15.9 2.4 4.8 8.1 0.0 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFO98487.1 - 0.027 14.2 2.3 0.1 12.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 KFO98487.1 - 0.041 13.7 2.4 3.9 7.2 0.0 3.2 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.1 KFO98487.1 - 0.33 11.3 9.5 1.3 9.4 2.9 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 KFO98487.1 - 1.4 9.5 6.5 88 3.7 0.1 4.8 5 0 0 5 5 5 0 HEAT-like repeat TPR_6 PF13174.1 KFO98487.1 - 1.9 9.1 8.1 7.5 7.2 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex2_Pex12 PF04757.9 KFO98488.1 - 5.3e-51 173.2 6.5 6.9e-51 172.8 4.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KFO98488.1 - 0.00082 19.3 5.1 0.0013 18.6 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO98488.1 - 0.0056 16.3 3.0 0.01 15.5 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO98488.1 - 0.12 12.1 8.8 0.78 9.6 6.1 2.1 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 KFO98488.1 - 0.78 9.4 4.0 1.4 8.6 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Adaptin_N PF01602.15 KFO98489.1 - 7.1e-165 549.2 13.5 9.1e-165 548.9 9.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 KFO98489.1 - 9.5e-38 128.5 0.2 2.5e-37 127.2 0.1 1.8 2 0 0 2 2 1 1 Beta2-adaptin appendage, C-terminal sub-domain Cnd1 PF12717.2 KFO98489.1 - 3.7e-37 127.8 7.1 1.9e-35 122.3 0.4 4.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFO98489.1 - 5.5e-23 81.0 5.2 1.4e-08 34.8 0.1 5.8 2 1 5 7 7 7 5 HEAT repeats HEAT PF02985.17 KFO98489.1 - 6.1e-13 47.6 7.7 0.0038 17.1 0.0 6.9 7 0 0 7 7 7 4 HEAT repeat Alpha_adaptinC2 PF02883.15 KFO98489.1 - 2.3e-11 44.0 0.3 5.1e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Arm PF00514.18 KFO98489.1 - 4.8e-08 32.5 3.0 0.0045 16.7 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KFO98489.1 - 3.5e-05 24.1 5.4 1.3 9.6 0.0 6.5 6 2 1 7 7 7 2 HEAT-like repeat Cnd3 PF12719.2 KFO98489.1 - 0.00024 20.1 3.6 0.0014 17.7 0.2 2.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 KFO98489.1 - 0.00027 20.3 2.7 0.86 8.9 0.1 4.1 2 2 0 2 2 2 2 CLASP N terminal MOR2-PAG1_C PF14225.1 KFO98489.1 - 0.033 13.9 1.2 0.52 10.0 0.0 2.6 2 1 1 3 3 3 0 Cell morphogenesis C-terminal Vitellogenin_N PF01347.17 KFO98489.1 - 0.045 11.9 0.1 1.9 6.5 0.0 2.4 1 1 0 2 2 2 0 Lipoprotein amino terminal region Ras PF00071.17 KFO98490.1 - 4.3e-25 87.9 0.0 8.4e-25 87.0 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFO98490.1 - 1e-14 55.0 0.0 2.3e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO98490.1 - 0.00054 19.2 0.0 0.0087 15.3 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFO98490.1 - 0.0051 16.7 0.0 0.0072 16.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KFO98490.1 - 0.0054 16.6 0.0 0.0096 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFO98490.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFO98490.1 - 0.093 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 KFO98490.1 - 0.13 12.0 0.1 0.27 11.0 0.0 1.9 1 1 0 1 1 1 0 Dynamin family TAS2R PF05296.8 KFO98491.1 - 2e-57 194.3 36.5 2.3e-57 194.1 25.3 1.0 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) WBP-1 PF11669.3 KFO98491.1 - 0.073 13.1 0.0 0.073 13.1 0.0 3.5 3 2 1 4 4 4 0 WW domain-binding protein 1 TAS2R PF05296.8 KFO98492.1 - 2.5e-53 180.9 36.5 2.9e-53 180.7 25.3 1.0 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) TAS2R PF05296.8 KFO98493.1 - 1.2e-55 188.5 33.3 1.4e-55 188.3 23.1 1.0 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) Astacin PF01400.19 KFO98494.1 - 1.4e-66 223.5 0.1 2.2e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.18 KFO98494.1 - 9.9e-39 132.6 0.1 1.6e-38 132.0 0.1 1.3 1 0 0 1 1 1 1 MAM domain MATH PF00917.21 KFO98494.1 - 5.3e-25 87.9 0.8 8.8e-25 87.2 0.1 1.8 2 0 0 2 2 2 1 MATH domain EGF PF00008.22 KFO98494.1 - 1.1e-08 34.8 4.8 3.4e-08 33.2 3.3 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.10 KFO98494.1 - 0.21 11.6 6.1 0.57 10.2 4.3 1.7 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF_2 PF07974.8 KFO98494.1 - 8.1 6.7 14.8 0.4 10.8 5.6 2.4 2 0 0 2 2 2 0 EGF-like domain 7tm_2 PF00002.19 KFO98495.1 - 3.7e-34 117.8 20.0 3.7e-34 117.8 13.9 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) I-set PF07679.11 KFO98495.1 - 1.5e-14 53.5 2.4 2.7e-09 36.7 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain GPS PF01825.16 KFO98495.1 - 4.4e-14 52.3 2.2 4.4e-14 52.3 1.5 2.2 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain SEA PF01390.15 KFO98495.1 - 7.6e-14 51.3 0.2 2.6e-13 49.5 0.2 1.9 1 0 0 1 1 1 1 SEA domain Ig_2 PF13895.1 KFO98495.1 - 9.5e-13 48.0 17.4 3.1e-07 30.4 0.2 4.5 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.20 KFO98495.1 - 1.2e-09 38.0 7.0 3.2e-06 27.1 0.3 3.3 2 0 0 2 2 2 2 Immunoglobulin domain DUF3497 PF12003.3 KFO98495.1 - 1.6e-09 37.4 2.7 2.9e-09 36.5 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) V-set PF07686.12 KFO98495.1 - 1.3e-07 31.4 12.8 1.9e-06 27.7 0.7 3.8 3 1 0 3 3 3 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO98495.1 - 2.3e-06 27.9 20.1 0.0015 19.0 1.0 4.2 3 1 0 3 3 3 2 Immunoglobulin domain SFTA2 PF15210.1 KFO98495.1 - 0.38 10.3 4.7 3.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Surfactant-associated protein 2 SH3_9 PF14604.1 KFO98498.1 - 5.8e-45 150.6 4.9 5e-16 58.0 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFO98498.1 - 1.6e-39 133.0 8.0 4.2e-13 48.4 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 KFO98498.1 - 2.7e-35 119.6 5.3 5.3e-12 45.0 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain DUF1664 PF07889.7 KFO98498.1 - 0.97 9.2 2.8 1.8 8.3 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Patched PF02460.13 KFO98499.1 - 9.2e-78 261.9 25.0 3.4e-71 240.2 11.4 3.1 1 1 2 3 3 3 3 Patched family Sterol-sensing PF12349.3 KFO98499.1 - 7.8e-17 61.1 4.8 7.8e-17 61.1 3.4 3.1 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Ycf54 PF10674.4 KFO98499.1 - 0.0054 16.8 0.2 6.4 6.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2488) Calici_coat_C PF08435.6 KFO98499.1 - 0.011 15.0 0.2 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal DUF1133 PF06576.6 KFO98499.1 - 0.13 11.4 0.0 19 4.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) FAM176 PF14851.1 KFO98501.1 - 1.6e-64 216.2 0.1 1.9e-64 215.9 0.1 1.0 1 0 0 1 1 1 1 FAM176 family PDGLE PF13190.1 KFO98501.1 - 0.043 13.4 0.1 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 PDGLE domain DUF755 PF05501.6 KFO98501.1 - 1.2 9.2 6.3 1.7 8.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_L19 PF01245.15 KFO98502.1 - 8.4e-18 64.2 0.0 1.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 GCFC PF07842.7 KFO98503.1 - 2.7e-26 92.5 8.1 2.8e-26 92.5 3.4 2.4 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein NTR2 PF15458.1 KFO98503.1 - 9.4e-05 21.7 3.2 9.4e-05 21.7 2.2 2.6 3 0 0 3 3 3 1 Nineteen complex-related protein 2 Terminase_2 PF03592.11 KFO98503.1 - 0.031 14.5 2.0 0.093 13.0 1.4 1.8 1 0 0 1 1 1 0 Terminase small subunit Senescence_reg PF04520.8 KFO98504.1 - 0.12 12.9 5.1 0.15 12.5 3.5 1.2 1 0 0 1 1 1 0 Senescence regulator Dehydrin PF00257.14 KFO98504.1 - 7.5 6.8 8.5 0.46 10.7 2.4 1.6 2 0 0 2 2 2 0 Dehydrin SOCS PF12610.3 KFO98504.1 - 8.2 6.8 9.5 1 9.7 1.5 2.9 2 1 0 2 2 2 0 Suppressor of cytokine signalling SH3_9 PF14604.1 KFO98505.1 - 1.1e-68 226.5 7.7 3.3e-16 58.6 0.0 5.4 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.23 KFO98505.1 - 3.4e-66 218.4 9.6 2.4e-16 58.8 0.1 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.12 KFO98505.1 - 2.2e-57 190.3 1.3 2.2e-13 49.4 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.15 KFO98505.1 - 9.6e-44 149.3 0.1 9.6e-44 149.3 0.1 3.2 2 1 0 2 2 1 1 RhoGEF domain EF-hand_4 PF12763.2 KFO98505.1 - 1.2e-29 102.0 0.0 1.6e-13 50.2 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 KFO98505.1 - 3e-20 71.8 0.0 6.8e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KFO98505.1 - 1.2e-09 38.2 0.0 3.2e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFO98505.1 - 1.8e-09 36.2 0.3 0.0046 16.1 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFO98505.1 - 1.4e-06 27.6 0.4 2.2 8.3 0.0 4.1 3 0 0 3 3 3 3 EF-hand domain PH PF00169.24 KFO98505.1 - 3.4e-05 24.0 0.1 0.00018 21.6 0.1 2.4 1 0 0 1 1 1 1 PH domain EF-hand_8 PF13833.1 KFO98505.1 - 0.0016 18.0 0.2 0.16 11.5 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair DUF3104 PF11302.3 KFO98505.1 - 0.026 13.8 6.3 2.8 7.3 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3104) EF-hand_5 PF13202.1 KFO98505.1 - 0.041 13.2 1.1 7.2 6.1 0.1 3.1 3 0 0 3 3 3 0 EF hand Profilin PF00235.14 KFO98507.1 - 2.9e-18 66.1 0.0 3.6e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Profilin ADH_zinc_N PF00107.21 KFO98508.1 - 5.6e-23 80.9 0.1 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFO98508.1 - 6.1e-18 65.9 0.0 4.3e-17 63.1 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFO98508.1 - 4.8e-11 42.3 0.1 1.7e-08 34.1 0.0 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain DUF4147 PF13660.1 KFO98508.1 - 0.023 13.8 0.5 0.57 9.2 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4147) RRM_1 PF00076.17 KFO98509.1 - 2.5e-16 59.0 0.2 1.9e-15 56.2 0.0 2.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98509.1 - 2.3e-11 43.5 0.0 4.9e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO98509.1 - 6.8e-09 35.4 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3791 PF12668.2 KFO98509.1 - 0.038 13.5 0.2 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) FKBP_C PF00254.23 KFO98510.1 - 1.7e-26 92.0 0.0 1.8e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4613 PF15390.1 KFO98511.1 - 0 1060.6 0.1 0 1060.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) DUF4613 PF15390.1 KFO98512.1 - 0 1027.2 0.2 0 1027.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) SEP PF08059.8 KFO98513.1 - 7.8e-26 90.1 0.8 1.4e-25 89.3 0.1 1.7 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KFO98513.1 - 3.5e-13 49.4 0.2 1.1e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 UBX domain Spt20 PF12090.3 KFO98513.1 - 0.0004 19.7 0.0 0.00046 19.5 0.0 1.4 1 1 0 1 1 1 1 Spt20 family AAA PF00004.24 KFO98514.1 - 6.5e-48 162.2 0.0 7.7e-41 139.3 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 KFO98514.1 - 1.2e-18 66.8 0.1 2.9e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_16 PF13191.1 KFO98514.1 - 3.1e-08 33.8 0.5 1.9e-05 24.7 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KFO98514.1 - 5.2e-06 26.6 0.1 0.0033 17.5 0.1 3.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFO98514.1 - 6.6e-06 25.6 0.0 6.4e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KFO98514.1 - 7.8e-05 22.6 0.0 0.00026 20.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KFO98514.1 - 0.00024 20.7 0.0 0.032 13.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KFO98514.1 - 0.00053 20.0 0.0 0.57 10.2 0.0 3.3 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_5 PF07728.9 KFO98514.1 - 0.0022 17.7 0.1 0.046 13.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KFO98514.1 - 0.0026 18.0 0.7 0.036 14.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFO98514.1 - 0.0088 16.8 2.9 0.014 16.1 0.0 2.8 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KFO98514.1 - 0.01 16.0 0.0 0.048 13.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 KFO98514.1 - 0.013 14.6 0.0 0.2 10.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KFO98514.1 - 0.015 14.2 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KFO98514.1 - 0.019 14.3 0.0 0.055 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFO98514.1 - 0.027 13.5 0.0 0.091 11.7 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFO98514.1 - 0.037 13.9 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KFO98514.1 - 0.037 12.7 0.0 0.14 10.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus NACHT PF05729.7 KFO98514.1 - 0.051 13.2 0.0 0.38 10.3 0.0 2.5 2 1 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 KFO98514.1 - 0.074 12.5 0.0 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 KFO98514.1 - 0.099 11.5 0.0 0.5 9.2 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 KFO98514.1 - 0.15 11.6 0.0 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rnk_N PF14760.1 KFO98515.1 - 0.25 11.4 1.9 16 5.6 0.3 2.5 1 1 1 2 2 2 0 Rnk N-terminus Kelch_1 PF01344.20 KFO98516.1 - 3.3e-48 160.9 11.8 1.7e-13 49.8 0.0 7.1 7 1 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 KFO98516.1 - 1.8e-46 154.4 9.3 4.8e-11 42.3 0.0 6.3 1 1 5 6 6 6 6 Kelch motif BACK PF07707.10 KFO98516.1 - 3.9e-31 106.9 0.3 8.7e-31 105.8 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFO98516.1 - 4e-29 100.1 3.4 1e-09 37.9 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFO98516.1 - 3.1e-24 85.0 0.9 7.4e-24 83.8 0.6 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFO98516.1 - 3.1e-23 80.5 2.9 7.7e-06 25.4 0.0 6.9 6 1 1 7 7 7 4 Kelch motif Kelch_5 PF13854.1 KFO98516.1 - 1.5e-18 66.3 11.9 0.00062 19.6 0.1 7.0 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 KFO98516.1 - 1.7e-18 66.2 4.6 1.7e-05 24.8 0.0 6.4 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF1668 PF07893.8 KFO98516.1 - 0.0029 16.7 0.0 0.067 12.3 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1668) DUF3342 PF11822.3 KFO98516.1 - 0.016 14.4 0.5 0.029 13.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) IGPS PF00218.16 KFO98516.1 - 0.13 11.2 0.7 0.3 10.0 0.1 1.8 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase PQQ_3 PF13570.1 KFO98516.1 - 0.2 12.0 3.9 38 4.7 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Yae1_N PF09811.4 KFO98517.1 - 1.1e-17 63.2 49.7 1.5e+04 -9.2 34.4 4.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF2305 PF10230.4 KFO98518.1 - 8.2e-85 284.4 0.0 1e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KFO98518.1 - 5.9e-09 36.1 0.0 9.8e-09 35.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFO98518.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KFO98518.1 - 0.0015 18.1 0.0 0.0063 16.1 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.7 KFO98518.1 - 0.062 12.6 0.2 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 KFO98518.1 - 0.13 11.2 0.1 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase TGF_beta PF00019.15 KFO98519.1 - 5.8e-38 129.3 0.3 8.2e-38 128.8 0.2 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFO98519.1 - 2e-17 63.3 0.0 2.9e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide PX PF00787.19 KFO98520.1 - 1.4e-12 47.3 0.7 2.6e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 PX domain Cas_CT1975 PF09344.5 KFO98520.1 - 0.21 10.8 1.0 0.3 10.4 0.7 1.2 1 0 0 1 1 1 0 CT1975-like protein RVT_1 PF00078.22 KFO98522.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.17 KFO98523.1 - 1.2e-57 193.8 0.0 1.4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98523.1 - 2.6e-17 63.4 0.0 3.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO98523.1 - 5.4e-11 42.0 0.0 1e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO98523.1 - 7e-05 22.3 0.1 0.00018 21.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFO98523.1 - 0.0061 15.7 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFO98523.1 - 0.042 13.0 0.0 0.065 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AA_permease_2 PF13520.1 KFO98524.1 - 3.8e-62 210.2 47.3 4.8e-62 209.8 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFO98524.1 - 2.7e-24 85.3 43.0 4.6e-24 84.5 29.8 1.3 1 1 0 1 1 1 1 Amino acid permease Fork_head PF00250.13 KFO98525.1 - 2.3e-43 146.1 0.0 2.5e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 Fork head domain ADK PF00406.17 KFO98526.1 - 1.2e-33 116.1 0.0 1.5e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KFO98526.1 - 6.1e-05 23.3 0.1 0.00011 22.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFO98526.1 - 0.00064 19.1 0.0 0.0039 16.6 0.0 1.9 2 0 0 2 2 2 1 Thymidylate kinase FeoC PF09012.5 KFO98526.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator STIL_N PF15253.1 KFO98527.1 - 7.7e-186 617.7 0.0 2e-185 616.3 0.0 1.7 2 0 0 2 2 2 1 SCL-interrupting locus protein N-terminus HLH PF00010.21 KFO98528.1 - 2.6e-18 65.4 0.2 2.8e-18 65.3 0.2 1.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PMBR PF09373.5 KFO98528.1 - 0.055 13.4 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein-binding repeat CopD PF05425.8 KFO98529.1 - 0.015 15.5 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Copper resistance protein D NfeD PF01957.13 KFO98529.1 - 0.027 14.6 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4307 PF14155.1 KFO98529.1 - 0.028 14.1 0.3 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) EI24 PF07264.6 KFO98529.1 - 0.033 13.6 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PrgH PF09480.5 KFO98529.1 - 0.052 12.4 0.0 0.06 12.2 0.0 1.0 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Epiglycanin_C PF14654.1 KFO98529.1 - 0.076 13.0 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region p450 PF00067.17 KFO98530.1 - 9.7e-124 413.3 0.0 1.1e-123 413.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EPO_TPO PF00758.13 KFO98530.1 - 0.011 15.4 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin p450 PF00067.17 KFO98531.1 - 2.9e-128 428.3 0.0 3.4e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP11 PF06644.6 KFO98532.1 - 8.8e-70 235.2 0.8 9.9e-70 235.0 0.6 1.0 1 0 0 1 1 1 1 ATP11 protein UPF0128 PF03673.8 KFO98532.1 - 0.084 12.1 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) Mob1_phocein PF03637.12 KFO98533.1 - 5.9e-76 254.0 0.6 6.7e-76 253.8 0.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family Homeobox PF00046.24 KFO98534.1 - 2e-22 78.5 3.7 7.1e-22 76.7 2.5 2.0 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFO98534.1 - 2.2e-06 26.9 1.5 6.2e-06 25.5 1.0 1.8 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFO98534.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Selenoprotein_S PF06936.6 KFO98534.1 - 0.061 12.8 3.3 0.14 11.7 2.3 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) LigA PF07746.6 KFO98534.1 - 0.075 13.0 0.2 0.26 11.3 0.1 2.0 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit HA PF03457.9 KFO98534.1 - 7.5 6.7 7.6 3.3 7.8 2.8 2.1 1 1 1 2 2 2 0 Helicase associated domain Amidase PF01425.16 KFO98535.1 - 3e-102 342.7 0.0 3.4e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 Amidase Nol1_Nop2_Fmu PF01189.12 KFO98536.1 - 2.3e-26 92.8 0.0 3.5e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KFO98536.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase UCR_hinge PF02320.11 KFO98537.1 - 7.3e-21 73.8 8.6 7.8e-21 73.7 6.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein GDNF PF02351.11 KFO98537.1 - 0.023 15.2 6.2 0.027 14.9 4.3 1.1 1 0 0 1 1 1 0 GDNF/GAS1 domain Toxin_44 PF15523.1 KFO98537.1 - 0.036 13.9 1.0 0.042 13.7 0.7 1.1 1 0 0 1 1 1 0 Putative toxin 44 HrpB7 PF09486.5 KFO98537.1 - 0.068 13.0 1.9 0.068 13.0 1.3 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) LRR_6 PF13516.1 KFO98538.1 - 0.00043 20.0 6.3 9.7 6.6 0.1 6.2 6 0 0 6 6 6 3 Leucine Rich repeat SNF2_N PF00176.18 KFO98539.1 - 5.6e-39 133.7 0.0 1.1e-38 132.7 0.0 1.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFO98539.1 - 3.5e-13 49.2 0.0 7.3e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFO98539.1 - 1.1e-08 34.2 0.0 2.6e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.5 KFO98539.1 - 1.1e-05 25.3 0.1 0.00016 21.5 0.1 2.3 2 0 0 2 2 2 1 Rad54 N terminal DEAD PF00270.24 KFO98539.1 - 0.054 12.9 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF3529 PF12046.3 KFO98539.1 - 0.055 12.4 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) ResIII PF04851.10 KFO98539.1 - 0.078 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFO98539.1 - 0.17 10.8 0.0 0.5 9.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GNT-I PF03071.10 KFO98540.1 - 6.2e-51 173.3 0.2 1.3e-50 172.2 0.2 1.4 1 1 0 1 1 1 1 GNT-I family Tetraspannin PF00335.15 KFO98541.1 - 1.1e-43 149.0 15.3 1.3e-43 148.8 10.6 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF872 PF05915.7 KFO98541.1 - 7 6.5 13.4 0.26 11.1 4.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SH2 PF00017.19 KFO98542.1 - 2.9e-41 139.1 0.0 2.1e-19 69.0 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.22 KFO98542.1 - 1.7e-18 66.6 0.1 1.3e-17 63.7 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.23 KFO98542.1 - 1.1e-06 27.9 0.3 0.00027 20.2 0.0 2.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFO98542.1 - 3.9e-06 26.3 0.1 1.3e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO98542.1 - 0.00017 20.9 0.0 0.00042 19.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1338 PF07063.8 KFO98542.1 - 0.019 14.0 1.4 0.031 13.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) ATG11 PF10377.4 KFO98542.1 - 0.03 14.1 0.1 0.03 14.1 0.0 1.9 2 0 0 2 2 2 0 Autophagy-related protein 11 IncA PF04156.9 KFO98542.1 - 0.074 12.6 11.8 0.14 11.7 8.2 1.4 1 0 0 1 1 1 0 IncA protein Zeta_toxin PF06414.7 KFO98542.1 - 0.17 10.9 4.1 0.28 10.2 2.9 1.3 1 0 0 1 1 1 0 Zeta toxin CENP-Q PF13094.1 KFO98542.1 - 0.53 10.2 11.9 1.1 9.2 8.2 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1908 PF08926.6 KFO98543.1 - 8.3e-149 493.9 0.4 8.3e-149 493.9 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.20 KFO98543.1 - 8.9e-65 218.4 0.0 1.7e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98543.1 - 5.1e-27 94.5 0.0 9.7e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.19 KFO98543.1 - 5.4e-09 36.1 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO98543.1 - 4.1e-07 29.8 0.0 9.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.1 KFO98543.1 - 3.6e-05 22.8 0.2 0.00036 19.5 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 KFO98543.1 - 0.0005 19.8 0.0 0.053 13.2 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 KFO98543.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain RIO1 PF01163.17 KFO98543.1 - 0.026 13.8 0.1 0.026 13.8 0.0 2.0 3 0 0 3 3 3 0 RIO1 family Folate_rec PF03024.9 KFO98545.1 - 2.2e-51 173.7 26.1 2.2e-51 173.7 18.1 1.6 2 0 0 2 2 2 1 Folate receptor family Kelch_1 PF01344.20 KFO98546.1 - 9.7e-80 261.9 15.5 2.9e-15 55.5 0.3 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFO98546.1 - 1.2e-51 170.8 3.8 6.3e-10 38.8 0.0 6.3 1 1 5 6 6 6 6 Kelch motif BACK PF07707.10 KFO98546.1 - 1.5e-30 105.0 0.8 3.8e-30 103.7 0.3 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFO98546.1 - 8e-30 102.3 6.2 1.9e-06 27.8 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFO98546.1 - 2.1e-29 101.7 0.0 4.1e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 KFO98546.1 - 3.9e-28 96.9 4.5 0.00014 21.5 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFO98546.1 - 7.4e-26 88.9 6.8 2.9e-06 26.8 0.0 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KFO98546.1 - 4.4e-14 52.0 6.6 0.03 14.3 0.0 6.3 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.3 KFO98546.1 - 0.00036 19.7 0.0 0.0056 15.8 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) She2p PF11435.3 KFO98546.1 - 0.059 12.7 0.9 0.52 9.6 0.2 2.1 1 1 1 2 2 2 0 RNA binding protein She2p DUF3429 PF11911.3 KFO98547.1 - 1.4e-31 109.3 6.9 1.8e-31 109.0 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Vasculin PF15337.1 KFO98548.1 - 2.6e-44 149.6 4.8 8.2e-44 148.0 3.3 1.9 1 0 0 1 1 1 1 Vascular protein family Vasculin-like 1 SHNi-TPR PF10516.4 KFO98550.1 - 2.6e-15 55.3 5.7 1.1e-14 53.4 0.9 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_2 PF07719.12 KFO98550.1 - 2.8e-09 36.1 7.7 0.016 15.0 0.2 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFO98550.1 - 9.4e-09 34.8 11.9 8.4e-06 25.3 3.1 3.4 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 KFO98550.1 - 1.8e-08 34.1 15.9 1e-06 28.6 4.2 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFO98550.1 - 9e-08 31.4 6.0 0.014 14.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFO98550.1 - 0.0012 18.5 6.7 3.7 7.5 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO98550.1 - 0.0043 17.5 9.1 0.022 15.3 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFO98550.1 - 0.015 15.9 17.8 0.2 12.3 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFO98550.1 - 0.13 12.8 6.9 5.7 7.6 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFO98550.1 - 0.75 9.7 4.2 14 5.8 0.3 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 KFO98551.1 - 6.6e-60 202.3 0.0 7.6e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AhpC-TSA PF00578.16 KFO98552.1 - 6.3e-43 145.4 0.1 1.2e-42 144.4 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KFO98552.1 - 1.6e-17 63.4 0.0 2.1e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFO98552.1 - 6.1e-15 54.5 0.1 1.1e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Pkinase PF00069.20 KFO98556.1 - 1.4e-34 119.4 0.0 1.7e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98556.1 - 1.9e-34 118.9 0.0 2.3e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO98556.1 - 0.016 14.2 0.1 0.035 13.1 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.20 KFO98557.1 - 7.8e-21 74.3 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KFO98557.1 - 1.2e-17 63.3 0.0 2.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.18 KFO98557.1 - 1.2e-05 24.7 0.1 4.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 KFO98557.1 - 0.017 15.3 5.4 0.017 15.3 3.7 2.4 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III SelP_N PF04592.9 KFO98558.1 - 8.1e-26 90.8 1.0 8.7e-26 90.7 0.7 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Ribosomal_L37e PF01907.14 KFO98558.1 - 0.12 12.1 0.1 0.81 9.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L37e SWIM PF04434.12 KFO98559.1 - 0.027 13.9 1.9 0.075 12.5 1.3 1.8 1 0 0 1 1 1 0 SWIM zinc finger URO-D PF01208.12 KFO98560.1 - 5.1e-128 426.7 0.0 5.8e-128 426.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) HECT PF00632.20 KFO98562.1 - 7e-53 179.8 0.1 9.3e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MTH865 PF07747.6 KFO98562.1 - 0.052 13.1 0.0 0.23 11.1 0.0 2.0 3 0 0 3 3 3 0 MTH865-like family NTP_transferase PF00483.18 KFO98563.1 - 2.6e-17 62.9 0.0 4.9e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KFO98563.1 - 1.1e-15 58.0 0.0 1.6e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 KFO98563.1 - 0.00096 18.5 12.1 0.046 13.2 1.8 3.6 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) IspD PF01128.14 KFO98563.1 - 0.0037 16.8 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase BTB PF00651.26 KFO98564.1 - 1.5e-19 70.0 0.1 6e-18 64.8 0.0 2.2 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 KFO98564.1 - 7.6e-12 44.9 0.3 8.8e-11 41.5 0.1 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch Tctex-1 PF03645.8 KFO98565.1 - 2.2e-20 72.3 0.0 2.5e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Pkinase PF00069.20 KFO98566.1 - 1.1e-70 237.7 0.0 2e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 KFO98566.1 - 5.3e-38 128.8 3.0 5e-18 64.8 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 KFO98566.1 - 1.5e-35 122.5 0.0 2.3e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO98566.1 - 1.6e-09 37.2 0.0 7.7e-08 31.6 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KFO98566.1 - 0.031 14.0 0.1 5.7 6.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S8e PF01201.17 KFO98567.1 - 8.9e-49 165.0 1.3 1e-48 164.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Kinesin PF00225.18 KFO98568.1 - 2.3e-94 315.8 1.9 2.5e-94 315.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF2390 PF09523.5 KFO98568.1 - 0.022 14.9 1.2 0.038 14.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Drf_GBD PF06371.8 KFO98569.1 - 0.0026 17.1 0.1 0.0049 16.2 0.1 1.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain OST-HTH PF12872.2 KFO98569.1 - 0.072 12.9 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 OST-HTH/LOTUS domain DUF829 PF05705.9 KFO98570.1 - 1.6e-61 208.0 0.0 1.8e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KFO98570.1 - 0.00044 20.1 0.1 0.00051 19.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-C3HC4_2 PF13923.1 KFO98571.1 - 8.6e-09 35.2 10.5 8.6e-09 35.2 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO98571.1 - 5.2e-05 22.9 10.4 5.2e-05 22.9 7.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO98571.1 - 0.00029 20.4 7.1 0.00029 20.4 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO98571.1 - 0.001 18.6 10.0 0.001 18.6 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO98571.1 - 0.0014 18.3 8.0 0.0014 18.3 5.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Endonuclease_7 PF02945.10 KFO98571.1 - 0.0053 16.4 5.0 0.034 13.8 1.2 2.5 2 0 0 2 2 2 1 Recombination endonuclease VII DZR PF12773.2 KFO98571.1 - 0.23 11.3 4.9 3.4 7.5 1.4 2.9 2 0 0 2 2 2 0 Double zinc ribbon zf-Apc11 PF12861.2 KFO98571.1 - 0.43 10.4 5.4 0.17 11.7 1.8 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_A_type_inc PF04508.7 KFO98571.1 - 0.64 9.9 4.8 0.34 10.7 0.6 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RNase_T PF00929.19 KFO98572.1 - 5.5e-38 130.8 0.0 6.6e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DMAP1 PF05499.7 KFO98573.1 - 5e-81 270.4 6.8 8.3e-81 269.7 4.7 1.3 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF498 PF04430.9 KFO98573.1 - 0.078 12.5 0.0 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Atg14 PF10186.4 KFO98573.1 - 0.24 10.3 10.7 0.43 9.4 6.5 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C2H2 PF00096.21 KFO98574.1 - 2.2e-17 62.2 21.0 7.2e-06 26.0 3.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO98574.1 - 2.5e-13 49.6 13.3 2.4e-07 30.7 3.4 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO98574.1 - 5.4e-13 48.2 19.4 0.00016 21.7 2.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFO98574.1 - 0.023 14.8 11.2 0.43 10.8 0.7 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO98574.1 - 0.024 14.7 10.5 0.14 12.3 0.8 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFO98574.1 - 0.043 13.5 14.0 0.61 9.8 2.0 3.1 2 1 0 2 2 2 0 BED zinc finger CTP-dep_RFKase PF01982.11 KFO98574.1 - 0.077 12.6 0.0 2.2 7.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF120 HTH_18 PF12833.2 KFO98574.1 - 0.11 12.5 0.6 6.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain zf-C2H2_2 PF12756.2 KFO98574.1 - 0.14 12.3 8.6 8.5 6.5 5.9 2.3 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ogr_Delta PF04606.7 KFO98574.1 - 0.24 11.1 1.6 0.35 10.5 0.1 2.1 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger zf-C2HC_2 PF13913.1 KFO98574.1 - 0.45 10.2 4.4 2.2 8.0 0.3 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 KFO98574.1 - 0.46 10.9 7.0 0.54 10.6 0.5 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger Zn_Tnp_IS1 PF03811.8 KFO98574.1 - 0.62 9.6 6.8 0.074 12.5 1.5 1.8 2 0 0 2 2 2 0 InsA N-terminal domain zf-H2C2_5 PF13909.1 KFO98574.1 - 0.94 9.8 0.1 0.94 9.8 0.1 3.6 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.1 KFO98574.1 - 5.7 6.8 6.1 8.2 6.3 0.3 2.4 2 1 0 2 2 2 0 Zinc-finger SNF PF00209.13 KFO98575.1 - 4.1e-144 480.9 23.8 4.6e-144 480.7 16.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.12 KFO98575.1 - 0.24 10.9 4.9 0.49 9.9 3.4 1.5 1 0 0 1 1 1 0 Caveolin Glyco_transf_7N PF13733.1 KFO98576.1 - 9.2e-47 157.8 0.1 1.4e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFO98576.1 - 6.9e-31 105.5 1.0 1.6e-30 104.3 0.7 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFO98576.1 - 1.3e-07 31.0 0.2 0.00021 20.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Sigma_reg_N PF13800.1 KFO98576.1 - 0.1 12.6 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal ATP-synt_C PF00137.16 KFO98577.1 - 2.4e-29 101.0 29.3 6.8e-16 57.9 5.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Diphthamide_syn PF01866.12 KFO98578.1 - 1.7e-74 250.8 0.0 2.2e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Xpo1 PF08389.7 KFO98579.1 - 4.5e-28 98.0 9.6 2.4e-24 85.9 0.3 4.4 4 1 0 4 4 4 3 Exportin 1-like protein IBN_N PF03810.14 KFO98579.1 - 6.4e-07 29.1 2.9 9.1e-07 28.7 0.3 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Glyco_transf_29 PF00777.13 KFO98580.1 - 8e-72 241.5 0.0 1e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Y_phosphatase PF00102.22 KFO98581.1 - 4.4e-172 569.5 1.6 1.8e-88 295.8 0.1 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFO98581.1 - 4.2e-111 363.2 29.1 6.6e-17 61.4 0.4 8.9 8 0 0 8 8 8 8 Fibronectin type III domain I-set PF07679.11 KFO98581.1 - 5e-44 148.0 0.0 4.1e-16 58.6 0.0 4.1 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO98581.1 - 6.3e-24 83.9 0.0 7e-08 32.4 0.0 4.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFO98581.1 - 1.5e-19 70.1 3.7 0.00048 20.5 0.0 7.0 7 0 0 7 7 7 3 Immunoglobulin domain Interfer-bind PF09294.5 KFO98581.1 - 6.5e-16 58.2 0.1 0.023 14.7 0.0 7.5 8 0 0 8 8 8 3 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.20 KFO98581.1 - 1.9e-11 43.9 0.0 0.016 15.3 0.0 4.7 3 1 0 3 3 3 3 Immunoglobulin domain DSPc PF00782.15 KFO98581.1 - 1.3e-08 34.5 0.0 0.0026 17.3 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain V-set PF07686.12 KFO98581.1 - 1.5e-08 34.5 0.0 0.025 14.4 0.0 4.6 3 1 0 3 3 3 2 Immunoglobulin V-set domain Y_phosphatase3 PF13350.1 KFO98581.1 - 1.8e-07 31.5 0.0 0.071 13.3 0.0 3.4 3 0 0 3 3 3 2 Tyrosine phosphatase family C2-set_2 PF08205.7 KFO98581.1 - 8.9e-07 28.7 3.8 0.22 11.4 0.0 4.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Y_Y_Y PF07495.8 KFO98581.1 - 1.5e-06 27.8 0.8 0.017 14.8 0.0 3.5 3 0 0 3 3 3 2 Y_Y_Y domain PTPlike_phytase PF14566.1 KFO98581.1 - 1.1e-05 25.4 0.2 0.028 14.4 0.0 2.9 2 0 0 2 2 2 2 Inositol hexakisphosphate TMEM154 PF15102.1 KFO98581.1 - 0.00076 19.2 0.0 0.00076 19.2 0.0 1.9 2 0 0 2 2 1 1 TMEM154 protein family DUF2369 PF10179.4 KFO98581.1 - 0.021 13.9 0.2 27 3.7 0.0 4.3 4 1 1 5 5 5 0 Uncharacterised conserved protein (DUF2369) ICAM_N PF03921.9 KFO98581.1 - 0.088 12.2 0.0 0.38 10.2 0.0 2.1 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain YhjQ PF06564.7 KFO98581.1 - 0.29 10.4 0.0 0.61 9.4 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein DUF1410 PF07198.6 KFO98581.1 - 0.45 10.8 2.5 5.7 7.3 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) AP_endonuc_2 PF01261.19 KFO98582.1 - 1.2e-22 80.3 0.1 1.8e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Med8 PF10232.4 KFO98586.1 - 6.7e-81 271.1 0.6 8.1e-81 270.8 0.4 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Baculo_PEP_C PF04513.7 KFO98586.1 - 0.069 12.9 0.3 13 5.6 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ELO PF01151.13 KFO98587.1 - 1.4e-63 214.5 22.6 1.7e-63 214.2 15.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 KFO98588.1 - 2.3e-38 128.6 16.3 6.5e-11 41.6 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KFO98588.1 - 4e-08 33.1 0.9 0.0044 16.7 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 KFO98588.1 - 0.033 13.8 2.9 0.61 9.7 0.2 3.5 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Nup160 PF11715.3 KFO98588.1 - 0.11 10.5 5.6 11 4.0 0.1 3.7 2 2 1 3 3 3 0 Nucleoporin Nup120/160 EpoR_lig-bind PF09067.5 KFO98589.1 - 1.5e-30 105.2 1.5 3.4e-28 97.6 0.2 2.7 3 0 0 3 3 3 2 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFO98589.1 - 6.2e-16 58.3 2.8 3.7e-09 36.5 0.3 3.8 4 0 0 4 4 4 3 Fibronectin type III domain IL6Ra-bind PF09240.5 KFO98589.1 - 6.3e-08 32.6 3.0 0.0023 18.0 0.3 2.5 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFO98589.1 - 0.0002 21.0 2.8 0.00029 20.5 0.0 2.6 3 0 0 3 3 3 1 Tissue factor Interfer-bind PF09294.5 KFO98589.1 - 0.044 13.8 0.0 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Pkinase_Tyr PF07714.12 KFO98590.1 - 2e-84 282.6 0.0 2.9e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO98590.1 - 1.4e-42 145.6 0.0 3.6e-42 144.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFO98590.1 - 2.6e-29 101.1 0.6 3.2e-14 52.8 0.5 3.7 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.11 KFO98590.1 - 1.5e-08 34.3 0.0 0.0076 16.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO98590.1 - 1.7e-06 28.0 0.0 0.0045 17.0 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain hEGF PF12661.2 KFO98590.1 - 5.4e-06 26.1 41.9 0.0023 17.8 2.2 5.5 5 0 0 5 5 5 4 Human growth factor-like EGF ig PF00047.20 KFO98590.1 - 0.00072 19.6 0.2 0.027 14.6 0.1 2.8 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFO98590.1 - 0.11 12.3 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain APH PF01636.18 KFO98590.1 - 0.24 11.0 0.0 0.7 9.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family EGF_2 PF07974.8 KFO98590.1 - 4.2 7.6 62.0 0.028 14.6 11.1 5.0 4 1 0 4 4 3 0 EGF-like domain Laminin_EGF PF00053.19 KFO98590.1 - 7.4 6.5 42.8 1.9 8.4 13.1 4.0 1 1 2 3 3 2 0 Laminin EGF-like (Domains III and V) LRR19-TM PF15176.1 KFO98591.1 - 3e-34 116.7 0.0 5.2e-34 116.0 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.1 KFO98591.1 - 1.2e-17 63.3 20.2 2.9e-10 39.7 4.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFO98591.1 - 3e-11 42.6 17.5 5.8e-06 25.7 0.2 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO98591.1 - 6.3e-08 31.6 16.7 0.34 11.0 0.0 5.9 5 0 0 5 5 5 4 Leucine Rich Repeat LRRCT PF01463.19 KFO98591.1 - 0.00055 19.9 0.4 0.0026 17.8 0.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat C-terminal domain LRR_9 PF14580.1 KFO98591.1 - 0.0078 15.7 0.2 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KFO98591.1 - 0.64 10.2 24.5 2.7 8.3 0.1 5.8 3 1 2 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 KFO98591.1 - 3 8.4 21.3 28 5.5 0.2 5.9 5 0 0 5 5 5 0 Leucine rich repeat TMEM125 PF15109.1 KFO98592.1 - 1.2e-56 189.5 8.1 1.2e-56 189.5 5.6 2.0 2 0 0 2 2 2 1 TMEM125 protein family NfeD PF01957.13 KFO98592.1 - 0.17 12.0 10.0 1 9.4 1.8 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding UPF0182 PF03699.8 KFO98592.1 - 0.24 9.3 2.3 0.28 9.0 1.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4234 PF14018.1 KFO98592.1 - 0.45 10.2 0.0 0.45 10.2 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) IncA PF04156.9 KFO98592.1 - 0.93 9.0 21.9 1.9 8.0 2.8 2.4 2 0 0 2 2 2 0 IncA protein Serpentine_r_xa PF03383.10 KFO98592.1 - 1 9.0 4.8 1.1 8.9 1.2 2.3 1 1 2 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa Claudin_2 PF13903.1 KFO98592.1 - 1.2 8.8 17.8 1.1 8.9 6.4 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CopD PF05425.8 KFO98592.1 - 3.5 7.8 11.6 0.5 10.5 1.5 2.2 2 0 0 2 2 2 0 Copper resistance protein D DUF3185 PF11381.3 KFO98592.1 - 8.1 6.2 8.6 19 5.1 2.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3185) DUF2678 PF10856.3 KFO98592.1 - 8.9 6.0 8.2 6.9 6.4 1.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) WD40 PF00400.27 KFO98593.1 - 9.8e-13 47.4 10.2 0.00036 20.2 0.2 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Reo_sigmaC PF04582.7 KFO98593.1 - 0.0015 17.8 10.7 0.021 14.0 0.1 3.8 2 2 2 5 5 5 2 Reovirus sigma C capsid protein ADIP PF11559.3 KFO98593.1 - 0.0046 16.8 14.7 0.0046 16.8 10.2 6.0 2 1 4 6 6 6 3 Afadin- and alpha -actinin-Binding DUF3639 PF12341.3 KFO98593.1 - 0.18 11.8 0.2 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) Ebp2 PF05890.7 KFO98594.1 - 1.8e-84 283.2 27.5 2e-84 283.0 19.1 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Exonuc_VII_L PF02601.10 KFO98594.1 - 0.034 13.3 8.5 0.046 12.9 5.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 KFO98594.1 - 0.17 9.6 8.3 0.21 9.3 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4208 PF13907.1 KFO98594.1 - 0.83 9.9 9.4 4.7 7.4 6.5 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) GvpL_GvpF PF06386.6 KFO98594.1 - 0.99 8.9 10.4 0.099 12.2 3.5 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Cytochrom_B562 PF07361.6 KFO98594.1 - 1.2 9.5 14.8 3.4 8.1 10.3 1.8 1 0 0 1 1 1 0 Cytochrome b562 PEP-utilisers_N PF05524.8 KFO98594.1 - 3 7.6 8.1 19 5.0 0.9 3.1 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal AAA_11 PF13086.1 KFO98594.1 - 5.2 6.5 10.0 0.24 10.9 3.1 1.5 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.1 KFO98594.1 - 9.6 5.0 12.0 13 4.6 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM183 PF14886.1 KFO98595.1 - 6.1e-28 97.5 1.7 7e-28 97.3 1.2 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related LLC1 PF14945.1 KFO98595.1 - 0.16 12.2 0.8 0.23 11.7 0.6 1.3 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein PIF1 PF05970.9 KFO98596.1 - 1.7e-50 172.0 1.4 4.1e-48 164.1 1.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 KFO98596.1 - 3.6e-05 23.8 0.0 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 KFO98596.1 - 0.00015 21.3 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 KFO98596.1 - 0.00016 19.6 0.0 0.00023 19.0 0.0 1.1 1 0 0 1 1 1 1 Helicase Glyco_transf_29 PF00777.13 KFO98597.1 - 6e-40 137.0 0.1 6.8e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) YcfA PF07927.7 KFO98597.1 - 3.8 7.4 4.9 21 5.0 3.4 2.1 1 1 0 1 1 1 0 YcfA-like protein Peptidase_C13 PF01650.13 KFO98598.1 - 1.4e-40 139.2 0.0 1.9e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family ADK PF00406.17 KFO98599.1 - 1e-69 233.2 0.0 4.5e-34 117.5 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KFO98599.1 - 4.1e-14 53.4 0.0 9.4e-10 39.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFO98599.1 - 8.9e-11 42.1 0.2 6.5e-08 32.9 0.0 3.4 1 1 2 3 3 3 1 AAA domain AAA_33 PF13671.1 KFO98599.1 - 9.3e-06 25.5 0.0 0.00027 20.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KFO98599.1 - 0.00033 20.1 2.9 0.061 12.6 0.0 3.6 4 0 0 4 4 4 1 Thymidylate kinase Zeta_toxin PF06414.7 KFO98599.1 - 0.005 15.9 0.1 0.012 14.6 0.1 1.8 1 1 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KFO98599.1 - 0.02 14.6 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Myb_DNA-binding PF00249.26 KFO98600.1 - 5.2e-10 39.2 0.2 1.1e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFO98600.1 - 5.6e-07 29.5 0.1 1.9e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KFO98600.1 - 3.9e-05 23.1 7.4 3.9e-05 23.1 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type UCH PF00443.24 KFO98601.1 - 2.4e-69 233.4 0.0 8.2e-68 228.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO98601.1 - 3e-29 102.3 0.0 1.1e-27 97.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFO98601.1 - 7e-22 77.6 0.0 1.3e-12 47.9 0.0 3.2 2 0 0 2 2 2 2 DUSP domain zf-UBP PF02148.14 KFO98601.1 - 7.3e-12 45.2 4.8 7.3e-12 45.2 3.3 3.6 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2217 PF10265.4 KFO98602.1 - 1.9e-225 749.4 5.0 2.2e-225 749.3 3.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) I-set PF07679.11 KFO98603.1 - 5.2e-18 64.6 0.0 1.4e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO98603.1 - 8.5e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO98603.1 - 0.00039 20.4 0.1 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain KH_1 PF00013.24 KFO98604.1 - 8.3e-62 204.7 13.0 9.6e-18 63.5 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 KFO98604.1 - 2.8e-36 122.5 22.6 2.4e-11 43.0 0.5 4.9 4 1 0 4 4 4 4 KH domain KH_2 PF07650.12 KFO98604.1 - 5.1e-20 70.8 9.3 1.2e-05 24.7 0.2 4.3 4 0 0 4 4 4 4 KH domain DUF1897 PF09005.5 KFO98604.1 - 4.2e-16 58.1 26.1 6.2e-10 38.3 7.1 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.1 KFO98604.1 - 7.5e-07 28.6 7.1 0.057 13.0 0.1 4.3 4 0 0 4 4 4 2 KH domain Secretin_N PF03958.12 KFO98604.1 - 0.00056 20.0 0.6 0.06 13.5 0.2 3.3 3 1 1 4 4 4 1 Bacterial type II/III secretion system short domain KH_5 PF13184.1 KFO98604.1 - 0.0045 16.7 4.3 1.7 8.5 0.0 3.6 3 0 0 3 3 3 2 NusA-like KH domain DnaJ PF00226.26 KFO98605.1 - 1.7e-29 101.3 3.4 2.7e-29 100.7 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFO98605.1 - 2.2e-24 85.1 1.0 2.5e-21 75.3 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain PDZ PF00595.19 KFO98606.1 - 3.3e-08 33.5 0.2 6.6e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO98606.1 - 0.012 15.5 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 PDZ domain 7tm_1 PF00001.16 KFO98607.1 - 6.1e-12 45.2 9.6 7.2e-12 44.9 6.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sri PF10327.4 KFO98607.1 - 0.0016 17.4 1.0 0.0016 17.4 0.7 1.7 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Sri TPT PF03151.11 KFO98607.1 - 0.08 12.5 4.0 0.053 13.1 1.1 1.8 1 1 1 2 2 2 0 Triose-phosphate Transporter family DUF4405 PF14358.1 KFO98607.1 - 0.13 12.4 1.9 1 9.5 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) DUF898 PF05987.8 KFO98607.1 - 0.29 9.9 5.9 0.57 9.0 4.1 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) BatA PF07584.6 KFO98607.1 - 1.4 9.1 8.5 13 6.0 1.4 3.0 3 1 1 4 4 4 0 Aerotolerance regulator N-terminal YesK PF14150.1 KFO98607.1 - 4.7 7.3 9.1 1.8 8.7 0.7 2.9 2 1 1 3 3 3 0 YesK-like protein 7tm_2 PF00002.19 KFO98608.1 - 1.8e-56 190.9 27.6 2.8e-56 190.3 19.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3497 PF12003.3 KFO98608.1 - 4e-40 137.5 2.8 5.3e-40 137.1 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) EGF_CA PF07645.10 KFO98608.1 - 1.7e-16 59.9 42.0 1e-08 35.0 8.1 3.8 3 0 0 3 3 3 3 Calcium-binding EGF domain GPS PF01825.16 KFO98608.1 - 6.1e-16 58.2 6.3 1.6e-15 56.8 4.4 1.8 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain EGF_3 PF12947.2 KFO98608.1 - 1e-10 41.3 53.2 2.4e-05 24.1 4.9 5.1 5 0 0 5 5 5 3 EGF domain cEGF PF12662.2 KFO98608.1 - 8.1e-10 38.1 22.5 2e-07 30.5 0.4 3.8 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF PF00008.22 KFO98608.1 - 0.0071 16.2 46.4 0.009 15.9 5.4 5.4 4 2 0 4 4 4 2 EGF-like domain FXa_inhibition PF14670.1 KFO98608.1 - 0.1 12.7 42.3 0.022 14.9 7.0 4.7 3 2 1 4 4 4 0 Coagulation Factor Xa inhibitory site Latrophilin PF02354.11 KFO98610.1 - 1e-181 603.5 12.9 1.4e-181 603.0 8.9 1.2 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region OLF PF02191.11 KFO98610.1 - 2e-95 318.8 3.4 3.4e-95 318.0 2.3 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain 7tm_2 PF00002.19 KFO98610.1 - 7.5e-67 224.9 17.9 1.2e-66 224.2 12.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3497 PF12003.3 KFO98610.1 - 5.5e-65 218.7 0.4 8.1e-65 218.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) Gal_Lectin PF02140.13 KFO98610.1 - 1.3e-23 83.0 0.9 3.5e-23 81.7 0.6 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain GPS PF01825.16 KFO98610.1 - 3.4e-16 59.0 7.0 8.5e-16 57.7 4.8 1.7 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 KFO98610.1 - 8.8e-09 35.2 1.3 2.6e-08 33.7 0.9 1.9 1 0 0 1 1 1 1 Hormone receptor domain DUF2602 PF10782.4 KFO98610.1 - 0.4 10.5 6.1 0.9 9.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2602) TTL PF03133.10 KFO98611.1 - 1.6e-79 266.8 0.4 1.6e-79 266.8 0.3 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFO98611.1 - 9.5e-07 27.8 0.1 0.0041 15.9 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KFO98611.1 - 0.0002 21.1 0.0 0.00046 19.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFO98611.1 - 0.00081 19.2 0.0 0.0038 17.1 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFO98611.1 - 0.0031 16.3 0.0 0.027 13.1 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 KFO98611.1 - 0.041 13.3 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Pkinase PF00069.20 KFO98612.1 - 4.3e-70 235.8 0.0 5.7e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98612.1 - 9.3e-35 119.9 0.0 1.3e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO98612.1 - 6e-09 35.2 0.0 1.9e-08 33.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KFO98612.1 - 0.054 13.2 0.1 0.71 9.5 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family SAM_1 PF00536.25 KFO98613.1 - 1.4e-09 37.9 0.0 1.7e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFO98613.1 - 5e-05 23.0 0.0 6.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFO98613.1 - 6.8e-05 22.5 0.0 7.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Uricase PF01014.13 KFO98614.1 - 4.3e-50 169.3 0.0 4.9e-27 94.7 0.0 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.13 KFO98614.1 - 0.048 13.8 0.0 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 Dihydroneopterin aldolase Brix PF04427.13 KFO98615.1 - 1.6e-43 148.5 1.8 2e-43 148.2 1.3 1.1 1 0 0 1 1 1 1 Brix domain G-gamma PF00631.17 KFO98616.1 - 3.8e-16 58.5 0.0 4e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 GGL domain DUF3338 PF11819.3 KFO98616.1 - 0.011 15.2 0.0 0.012 15.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) TINF2_N PF14973.1 KFO98617.1 - 0.3 11.2 11.4 0.038 14.1 3.6 2.3 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Glyco_hydro_18 PF00704.23 KFO98618.1 - 2.8e-42 145.3 0.4 3.8e-42 144.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vitellogenin_N PF01347.17 KFO98619.1 - 1.1e-155 519.4 0.1 1.1e-155 519.4 0.1 2.2 2 0 0 2 2 2 1 Lipoprotein amino terminal region DUF1944 PF09175.5 KFO98619.1 - 6.1e-56 188.5 0.0 1.2e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) DUF1943 PF09172.6 KFO98619.1 - 4e-54 183.5 0.0 4e-54 183.5 0.0 3.3 2 2 0 2 2 2 1 Domain of unknown function (DUF1943) VWD PF00094.20 KFO98619.1 - 1.4e-28 100.0 0.0 1.4e-28 100.0 0.0 2.6 3 0 0 3 3 3 1 von Willebrand factor type D domain HEAT_2 PF13646.1 KFO98619.1 - 4.3e-06 26.9 1.3 0.085 13.1 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats TonB_C PF03544.9 KFO98619.1 - 0.09 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal DUF605 PF04652.11 KFO98619.1 - 1.3 8.3 40.5 2.5 7.3 28.1 1.5 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 KFO98619.1 - 8.7 4.6 40.6 12 4.1 28.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ADIP PF11559.3 KFO98620.1 - 2.6e-45 154.0 21.6 2.6e-45 154.0 14.9 4.1 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding Surfac_D-trimer PF09006.6 KFO98620.1 - 0.034 13.8 0.8 9.2 6.0 0.0 3.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation 7tm_1 PF00001.16 KFO98621.1 - 7.6e-36 123.5 24.6 1.2e-35 122.8 17.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3671 PF12420.3 KFO98621.1 - 5.7 6.9 12.8 0.55 10.2 3.2 2.8 2 1 1 3 3 3 0 Protein of unknown function PKD_channel PF08016.7 KFO98622.1 - 1.2e-10 40.3 9.4 2.1e-10 39.6 6.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel ATG27 PF09451.5 KFO98622.1 - 0.031 13.5 0.2 0.073 12.2 0.2 1.6 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF4522 PF15022.1 KFO98622.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) Claudin_3 PF06653.6 KFO98622.1 - 3.1 7.4 17.3 2.9 7.6 0.1 3.4 3 0 0 3 3 3 0 Tight junction protein, Claudin-like Ion_trans PF00520.26 KFO98622.1 - 8.9 5.4 23.6 39 3.3 16.3 2.1 1 1 0 1 1 1 0 Ion transport protein PKD_channel PF08016.7 KFO98623.1 - 2.7e-12 45.8 13.3 5.1e-12 44.9 9.2 1.4 1 0 0 1 1 1 1 Polycystin cation channel RhoGAP PF00620.22 KFO98624.1 - 1.6e-47 160.9 0.1 3.1e-47 159.9 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain CARD PF00619.16 KFO98625.1 - 8.3e-16 57.5 0.4 1.3e-15 57.0 0.2 1.2 1 0 0 1 1 1 1 Caspase recruitment domain Amidinotransf PF02274.12 KFO98626.1 - 9.8e-20 70.7 0.0 1.2e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase DUF4319 PF14203.1 KFO98626.1 - 1.9 8.0 3.8 11 5.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) Cys_knot PF00007.17 KFO98627.1 - 1.2e-16 60.6 13.5 1.2e-16 60.6 9.3 3.2 4 0 0 4 4 4 1 Cystine-knot domain VWC PF00093.13 KFO98627.1 - 2e-10 40.5 12.4 2e-10 40.5 8.6 4.9 3 1 2 5 5 5 1 von Willebrand factor type C domain TSP_1 PF00090.14 KFO98627.1 - 1.7e-09 37.6 8.6 1.7e-09 37.6 5.9 3.4 4 0 0 4 4 4 1 Thrombospondin type 1 domain Sclerostin PF05463.6 KFO98627.1 - 0.00028 20.4 5.8 0.0005 19.6 4.0 1.6 1 0 0 1 1 1 1 Sclerostin (SOST) zf-HIT PF04438.11 KFO98628.1 - 5.1e-05 22.8 13.5 5.1e-05 22.8 9.4 1.9 2 0 0 2 2 2 1 HIT zinc finger zf-B_box PF00643.19 KFO98628.1 - 0.7 9.8 8.7 1.5 8.7 6.0 1.6 1 0 0 1 1 1 0 B-box zinc finger Collagen PF01391.13 KFO98629.1 - 4.1e-146 474.6 567.5 2.4e-10 39.7 17.7 19.9 2 2 16 18 18 18 16 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFO98629.1 - 2.6e-47 161.0 0.3 1.4e-22 80.1 0.0 2.2 1 1 1 2 2 2 2 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.19 KFO98629.1 - 0.00087 19.3 0.2 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 Laminin G domain ADIP PF11559.3 KFO98630.1 - 0.00044 20.1 16.4 0.00044 20.1 11.4 6.1 1 1 6 7 7 7 1 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 KFO98630.1 - 0.016 15.0 13.8 0.016 15.0 9.6 6.1 2 2 3 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 KFO98630.1 - 4.5 6.3 20.8 1.3 8.0 3.8 4.2 2 2 2 4 4 4 0 Reovirus sigma C capsid protein BAR PF03114.13 KFO98631.1 - 7.8e-65 218.5 6.3 1e-64 218.2 4.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFO98631.1 - 9.3e-11 41.1 0.0 2.9e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.4 KFO98631.1 - 3.8e-09 35.8 1.0 4.5e-09 35.6 0.7 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SH3_1 PF00018.23 KFO98631.1 - 6.8e-08 31.7 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFO98631.1 - 7e-08 31.8 0.0 1.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Sep15_SelM PF08806.6 KFO98632.1 - 1.9e-14 53.1 0.0 2e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain Sulfotransfer_2 PF03567.9 KFO98634.1 - 4.8e-40 137.8 0.6 6.2e-40 137.4 0.4 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 KFO98634.1 - 0.00018 20.2 0.0 0.00026 19.7 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.22 KFO98634.1 - 0.0042 16.3 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain DUF2129 PF09902.4 KFO98634.1 - 0.13 12.0 1.3 0.36 10.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) RVT_1 PF00078.22 KFO98635.1 - 0.014 14.7 0.0 0.031 13.6 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 KFO98636.1 - 3.7e-61 206.5 0.0 7.6e-61 205.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98636.1 - 8.3e-39 133.2 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KFO98636.1 - 8e-33 112.0 14.4 1.8e-17 62.8 4.7 2.3 2 0 0 2 2 2 2 Hr1 repeat Uds1 PF15456.1 KFO98636.1 - 9.1e-07 28.9 5.6 0.00097 19.1 1.0 2.4 2 0 0 2 2 2 2 Up-regulated During Septation Kinase-like PF14531.1 KFO98636.1 - 4.9e-06 25.7 0.0 3.1e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF3416 PF11896.3 KFO98636.1 - 0.022 14.7 3.6 0.76 9.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) TFIIB PF00382.14 KFO98637.1 - 4.2e-53 177.0 2.2 6.3e-26 89.9 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KFO98637.1 - 1.3e-14 53.2 0.4 2e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 KFO98637.1 - 1.1e-08 34.6 0.0 4.8e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFO98637.1 - 0.00027 20.8 0.3 0.058 13.3 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 KFO98637.1 - 0.0034 16.6 0.1 0.094 12.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 DUF3733 PF12534.3 KFO98638.1 - 9.7e-44 146.5 12.0 4e-25 86.8 1.9 2.7 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 KFO98638.1 - 8.6e-36 121.4 48.9 7.8e-12 44.7 4.6 7.3 6 1 1 7 7 7 5 Leucine rich repeat LRR_4 PF12799.2 KFO98638.1 - 2.4e-28 97.2 58.9 2.7e-09 36.4 0.3 9.8 5 2 6 11 11 11 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFO98638.1 - 8.9e-07 28.6 8.4 0.00033 20.3 1.2 3.8 1 1 3 4 4 4 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFO98638.1 - 3e-06 26.5 47.3 0.0069 16.2 0.0 11.9 11 3 2 13 13 13 4 Leucine Rich Repeat LRR_6 PF13516.1 KFO98638.1 - 0.067 13.2 0.0 0.067 13.2 0.0 9.5 11 1 1 12 12 12 0 Leucine Rich repeat LRR_9 PF14580.1 KFO98638.1 - 0.11 11.9 14.4 0.099 12.1 0.4 3.4 1 1 2 3 3 3 0 Leucine-rich repeat LRR_7 PF13504.1 KFO98638.1 - 0.18 12.1 0.0 0.18 12.1 0.0 11.7 14 0 0 14 14 14 0 Leucine rich repeat DUF3733 PF12534.3 KFO98639.1 - 1.4e-54 181.2 8.5 7.4e-31 105.2 0.4 2.7 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 KFO98639.1 - 3.5e-36 122.7 49.2 2.9e-12 46.1 2.6 7.7 2 1 9 11 11 11 10 Leucine rich repeat LRR_4 PF12799.2 KFO98639.1 - 8.5e-31 105.0 37.0 2.5e-08 33.3 0.3 10.2 5 4 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO98639.1 - 1.4e-12 45.7 36.8 0.32 11.1 0.0 12.0 13 1 0 13 13 13 5 Leucine Rich Repeat LRR_5 PF13306.1 KFO98639.1 - 1.4e-08 34.4 8.8 0.00015 21.4 0.4 4.1 2 1 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO98639.1 - 5.8e-06 25.6 30.9 12 6.6 0.0 12.4 14 0 0 14 14 14 1 Leucine rich repeat VHL PF01847.11 KFO98639.1 - 0.074 12.6 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 von Hippel-Lindau disease tumour suppressor protein DUF3733 PF12534.3 KFO98640.1 - 7.2e-51 169.3 11.6 3.6e-28 96.6 0.7 2.8 2 0 0 2 2 2 2 Leucine-rich repeat containing protein 8 LRR_8 PF13855.1 KFO98640.1 - 3.2e-40 135.6 32.5 8.8e-14 51.0 2.5 6.8 5 2 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.2 KFO98640.1 - 1.6e-33 113.7 36.6 1e-09 37.7 0.6 9.0 6 1 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO98640.1 - 5e-19 65.3 27.0 0.0075 16.1 0.2 11.7 10 1 0 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 KFO98640.1 - 1.8e-11 42.2 32.6 0.1 12.8 0.4 12.3 12 1 0 12 12 12 4 Leucine rich repeat LRR_6 PF13516.1 KFO98640.1 - 3.4e-05 23.4 25.5 1.3 9.3 0.0 9.2 8 1 1 9 9 9 1 Leucine Rich repeat LRR_9 PF14580.1 KFO98640.1 - 0.0013 18.2 7.8 0.15 11.6 0.2 3.4 1 1 2 3 3 3 2 Leucine-rich repeat AKAP95 PF04988.7 KFO98641.1 - 3.3e-63 212.3 13.6 5.1e-63 211.7 9.4 1.3 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 KFO98641.1 - 0.043 13.9 10.3 0.64 10.1 1.1 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFO98641.1 - 0.057 13.5 8.5 0.14 12.2 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFO98641.1 - 0.21 11.8 8.0 0.32 11.3 0.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Eapp_C PF10238.4 KFO98641.1 - 2.9 7.7 9.1 1 9.2 1.8 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Homeobox PF00046.24 KFO98642.1 - 8e-20 70.2 2.1 1.1e-19 69.7 1.4 1.2 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFO98642.1 - 0.083 11.9 0.4 0.13 11.3 0.3 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-C2H2_4 PF13894.1 KFO98644.1 - 1.1e-13 50.4 48.7 0.0042 17.3 0.2 9.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO98644.1 - 1.3e-05 25.2 57.8 0.00044 20.4 0.3 9.0 8 1 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFO98644.1 - 0.0012 18.8 21.1 0.29 11.3 0.0 6.5 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFO98644.1 - 0.0032 17.5 9.4 0.0054 16.8 1.5 8.4 11 0 0 11 11 11 3 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.1 KFO98644.1 - 0.022 14.6 23.5 0.097 12.5 0.3 5.3 4 1 1 5 5 5 0 Zinc-finger zf-C2H2_6 PF13912.1 KFO98644.1 - 0.047 13.6 0.1 0.047 13.6 0.1 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO98644.1 - 3.6 8.0 51.5 1 9.7 3.1 10.1 9 1 1 10 10 10 0 Zinc-finger double domain RVT_1 PF00078.22 KFO98645.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Sec63 PF02889.11 KFO98646.1 - 7.4e-61 206.0 2.5 1.1e-60 205.4 1.8 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KFO98646.1 - 1.1e-27 96.5 0.0 4.3e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO98646.1 - 1.5e-11 43.9 0.0 5.3e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFO98646.1 - 2.5e-10 40.4 0.0 5.4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFO98646.1 - 0.013 15.6 0.0 0.069 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFO98646.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFO98646.1 - 2.9 8.1 6.6 3.5 7.8 0.0 3.2 4 0 0 4 4 4 0 AAA domain Pkinase PF00069.20 KFO98647.1 - 2.8e-46 157.7 0.0 3.5e-25 88.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98647.1 - 1.6e-16 60.2 0.0 2.9e-13 49.5 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase O-FucT PF10250.4 KFO98647.1 - 0.0058 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase APH PF01636.18 KFO98647.1 - 0.0076 16.0 0.0 0.03 14.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFO98647.1 - 0.11 11.4 0.5 5.4 5.8 0.0 2.7 3 0 0 3 3 3 0 Kinase-like Zona_pellucida PF00100.18 KFO98648.1 - 1.3e-43 149.3 0.3 2.5e-43 148.4 0.2 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Abhydrolase_6 PF12697.2 KFO98649.1 - 1.6e-35 123.0 0.0 2.1e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO98649.1 - 3.1e-23 82.5 0.0 3.8e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFO98649.1 - 2.3e-14 53.3 0.0 3.5e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KFO98649.1 - 5.6e-05 21.7 0.0 0.0061 15.0 0.0 2.0 2 0 0 2 2 2 2 Ndr family Hydrolase_4 PF12146.3 KFO98649.1 - 0.00061 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 KFO98649.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KFO98649.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) BTB PF00651.26 KFO98650.1 - 8.8e-23 80.4 0.0 2.6e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain DUF4596 PF15363.1 KFO98651.1 - 5.6e-27 93.3 6.2 5.6e-27 93.3 4.3 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4596) DUF4580 PF15162.1 KFO98652.1 - 1.5e-56 190.2 0.7 1.7e-56 190.0 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4580) Kinetochor_Ybp2 PF08568.5 KFO98653.1 - 4.8e-86 289.4 19.9 5.9e-86 289.1 13.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-AD PF07776.10 KFO98653.1 - 0.0036 17.2 0.1 0.0036 17.2 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger associated domain (zf-AD) RPAP2_Rtr1 PF04181.8 KFO98654.1 - 1.3e-25 89.2 5.8 2.1e-25 88.6 2.2 2.3 2 0 0 2 2 2 1 Rtr1/RPAP2 family L31 PF09784.4 KFO98654.1 - 0.044 13.8 0.1 0.64 10.1 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 zf-H2C2_2 PF13465.1 KFO98655.1 - 2.3e-31 106.5 41.7 1.7e-06 27.9 1.4 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFO98655.1 - 2.5e-28 96.6 48.3 8.3e-06 25.8 0.7 6.7 7 0 0 7 7 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO98655.1 - 1.8e-24 84.2 32.9 0.00042 20.4 0.1 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO98655.1 - 1.2e-17 63.4 16.7 0.012 15.7 0.0 6.5 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO98655.1 - 2.4e-11 43.1 31.3 0.00021 21.0 1.0 6.4 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 KFO98655.1 - 2.2e-08 33.9 26.7 0.0073 16.4 0.3 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type C1_1 PF00130.17 KFO98655.1 - 0.00011 21.8 21.9 0.045 13.4 2.9 3.6 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.10 KFO98655.1 - 0.00045 19.9 29.1 0.012 15.4 0.4 5.9 5 1 1 6 6 6 2 BED zinc finger Prok-RING_1 PF14446.1 KFO98655.1 - 0.0015 18.1 14.0 7.1 6.4 0.0 6.2 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 Ta0938 PF11494.3 KFO98655.1 - 0.0026 17.8 0.7 0.4 10.8 0.0 2.6 2 1 0 2 2 2 1 Ta0938 zf-Di19 PF05605.7 KFO98655.1 - 0.0054 16.8 22.5 0.41 10.8 2.5 4.6 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFO98655.1 - 0.019 14.6 20.8 2.1 8.0 0.6 5.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type GAGA PF09237.6 KFO98655.1 - 0.071 12.7 6.8 5.5 6.6 0.0 4.2 2 2 2 4 4 4 0 GAGA factor zf-CHCC PF10276.4 KFO98655.1 - 0.083 12.7 0.2 0.083 12.7 0.1 4.5 5 0 0 5 5 4 0 Zinc-finger domain FYVE PF01363.16 KFO98655.1 - 0.26 11.2 27.1 7 6.6 6.3 4.1 1 1 2 3 3 3 0 FYVE zinc finger BolA PF01722.13 KFO98655.1 - 0.52 10.2 6.0 3.7 7.5 0.3 3.4 2 2 1 3 3 3 0 BolA-like protein Ribosomal_S27e PF01667.12 KFO98655.1 - 1.1 8.8 10.7 0.55 9.8 0.1 4.5 4 1 1 5 5 5 0 Ribosomal protein S27 zf-C2H2_2 PF12756.2 KFO98655.1 - 2.1 8.4 24.1 6.4 6.9 0.1 5.6 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 KFO98655.1 - 2.8 7.4 14.0 2.6 7.5 0.2 5.1 3 1 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 KFO98655.1 - 3.5 7.6 31.2 11 6.0 4.1 6.2 4 2 2 6 6 5 0 Zinc ribbon domain Arc_trans_TRASH PF08394.5 KFO98655.1 - 3.8 7.7 10.0 19 5.5 0.1 4.6 4 1 0 4 4 4 0 Archaeal TRASH domain Elf1 PF05129.8 KFO98655.1 - 4.2 7.1 18.8 0.38 10.4 1.2 3.7 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like HypA PF01155.14 KFO98655.1 - 5.2 6.7 11.7 6.5 6.4 0.4 3.3 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family HNH PF01844.18 KFO98655.1 - 8.2 6.3 20.3 3.2 7.7 0.4 5.4 6 0 0 6 6 5 0 HNH endonuclease RabGAP-TBC PF00566.13 KFO98656.1 - 3.3e-53 180.3 3.2 3.3e-53 180.3 2.2 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1129 PF06570.6 KFO98656.1 - 0.013 14.7 0.2 0.051 12.8 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4224 PF13986.1 KFO98656.1 - 0.046 13.2 0.2 0.15 11.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) DUF2730 PF10805.3 KFO98656.1 - 1.7 8.3 27.9 0.05 13.3 1.1 4.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2730) Ribosomal_L18p PF00861.17 KFO98657.1 - 6.8e-46 155.3 0.1 1.3e-45 154.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KFO98657.1 - 5.1e-36 123.1 8.7 1.1e-35 122.0 6.0 1.5 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DUF1476 PF07345.6 KFO98657.1 - 0.003 17.7 0.4 0.0062 16.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1476) PIP49_C PF12260.3 KFO98658.1 - 3.2e-67 225.5 0.1 5.5e-67 224.8 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 PIP49_N PF14875.1 KFO98658.1 - 4.8e-51 172.5 3.0 2e-50 170.5 0.1 2.2 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 EF-hand_7 PF13499.1 KFO98658.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair Mtf2_C PF14061.1 KFO98659.1 - 1.2e-29 101.9 0.1 2.5e-29 100.9 0.1 1.6 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD PF00628.24 KFO98659.1 - 8.3e-17 60.6 28.2 9.2e-12 44.4 5.6 2.4 2 0 0 2 2 2 2 PHD-finger DUF4537 PF15057.1 KFO98659.1 - 0.00063 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF3682 PF12446.3 KFO98659.1 - 0.00097 19.4 3.2 0.0017 18.6 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) DUF1325 PF07039.6 KFO98659.1 - 0.0046 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Prok-RING_1 PF14446.1 KFO98659.1 - 0.012 15.2 4.4 0.012 15.2 3.0 3.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 Chromo PF00385.19 KFO98659.1 - 0.061 13.0 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.1 KFO98659.1 - 3.4 7.0 22.8 0.16 11.3 4.7 3.3 2 1 0 2 2 2 0 PHD-finger EMP24_GP25L PF01105.19 KFO98660.1 - 2e-33 115.6 0.3 2.3e-33 115.4 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3110 PF11360.3 KFO98660.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Reo_sigmaC PF04582.7 KFO98661.1 - 0.00016 20.9 2.5 0.00016 20.9 1.7 7.0 2 2 4 7 7 7 5 Reovirus sigma C capsid protein DUF2968 PF11180.3 KFO98661.1 - 0.0026 17.1 6.7 0.0026 17.1 4.6 10.8 3 2 9 12 12 12 2 Protein of unknown function (DUF2968) TSC22 PF01166.13 KFO98661.1 - 0.0036 17.2 1.2 0.0036 17.2 0.8 13.2 11 3 4 16 16 16 2 TSC-22/dip/bun family bZIP_1 PF00170.16 KFO98661.1 - 0.0049 16.7 2.9 0.0049 16.7 2.0 14.7 12 5 4 16 16 16 2 bZIP transcription factor adh_short PF00106.20 KFO98662.1 - 4.5e-25 88.4 0.0 4.9e-24 85.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFO98662.1 - 3.8e-09 36.4 0.0 5.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFO98662.1 - 3.6e-05 23.6 0.0 0.00019 21.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KFO98662.1 - 0.00024 20.8 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KFO98662.1 - 0.012 15.5 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding CBFD_NFYB_HMF PF00808.18 KFO98663.1 - 8.5e-24 83.4 1.9 1.6e-23 82.5 0.5 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFO98663.1 - 6.3e-05 23.0 0.0 8.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KFO98663.1 - 0.056 13.1 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated AAA_32 PF13654.1 KFO98663.1 - 0.13 10.8 0.1 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain FCH PF00611.18 KFO98664.1 - 2.9e-19 69.0 0.2 2.9e-19 69.0 0.1 3.6 4 1 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KFO98664.1 - 4.2e-13 48.4 0.1 9.3e-13 47.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFO98664.1 - 4.8e-12 45.2 0.0 1.3e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO98664.1 - 7.2e-07 28.6 0.1 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFO98664.1 - 4.6e-05 23.5 0.1 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Lzipper-MIP1 PF14389.1 KFO98664.1 - 0.0005 20.1 2.2 0.0005 20.1 1.6 2.0 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 HR1 PF02185.11 KFO98664.1 - 0.006 16.3 1.6 0.006 16.3 1.1 3.8 4 0 0 4 4 4 1 Hr1 repeat COG5 PF10392.4 KFO98664.1 - 0.022 14.7 0.5 0.022 14.7 0.3 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.14 KFO98664.1 - 5.5 4.7 11.4 4.6 4.9 3.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Uds1 PF15456.1 KFO98664.1 - 8 6.4 19.4 0.027 14.4 1.3 3.4 2 1 0 2 2 2 0 Up-regulated During Septation SH2 PF00017.19 KFO98665.1 - 9.9e-15 54.1 0.0 2.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.14 KFO98665.1 - 1.2e-13 51.2 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain Fcf2 PF08698.6 KFO98666.1 - 2.1e-34 117.4 1.6 9.8e-34 115.3 0.1 2.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing MH1 PF03165.11 KFO98666.1 - 0.64 10.0 4.6 0.28 11.1 0.1 2.6 3 0 0 3 3 3 0 MH1 domain Aldo_ket_red PF00248.16 KFO98667.1 - 1.8e-07 30.3 0.0 2.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family YpjP PF14005.1 KFO98667.1 - 0.08 12.7 0.1 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 YpjP-like protein SHS2_FTSA PF02491.15 KFO98667.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA Steroid_dh PF02544.11 KFO98668.1 - 2.1e-25 89.2 5.6 3.9e-25 88.3 3.9 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ABC_tran PF00005.22 KFO98669.1 - 1.3e-55 187.4 0.0 3.6e-30 105.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFO98669.1 - 9.4e-52 176.1 29.2 2.6e-38 131.9 9.8 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFO98669.1 - 3.1e-20 73.3 0.1 1.2e-07 32.0 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_23 PF13476.1 KFO98669.1 - 0.00021 21.6 3.8 0.011 16.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KFO98669.1 - 0.0012 18.7 0.0 2.4 8.1 0.0 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KFO98669.1 - 0.0018 17.7 2.4 0.056 12.9 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KFO98669.1 - 0.033 13.2 0.0 18 4.2 0.0 3.2 2 1 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.14 KFO98669.1 - 0.078 12.1 0.0 40 3.3 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 KFO98669.1 - 0.1 12.0 4.9 2 7.8 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KFO98669.1 - 0.14 11.5 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFO98669.1 - 0.27 10.8 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 KFO98669.1 - 4.5 4.4 2.1 19 2.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_membrane_2 PF06472.10 KFO98670.1 - 9.7e-101 336.6 6.4 1.3e-100 336.2 4.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFO98670.1 - 4.4e-18 65.9 0.0 1e-17 64.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFO98670.1 - 0.00018 21.5 2.9 0.0044 17.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KFO98670.1 - 0.00059 20.2 0.0 0.0026 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFO98670.1 - 0.0015 17.7 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFO98670.1 - 0.0072 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFO98670.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 KFO98670.1 - 0.097 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 KFO98670.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KFO98670.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Interfer-bind PF09294.5 KFO98671.1 - 2.2e-21 75.8 0.3 2.2e-21 75.8 0.2 1.5 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFO98671.1 - 5.8e-19 67.8 0.2 1.4e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Tissue factor DUF912 PF06024.7 KFO98671.1 - 0.084 12.9 1.5 0.17 11.9 1.0 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 KFO98671.1 - 0.13 12.7 0.5 0.34 11.3 0.4 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF869 PF05911.6 KFO98671.1 - 0.16 10.2 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) TMEM154 PF15102.1 KFO98671.1 - 0.5 10.0 2.0 1.2 8.8 1.4 1.7 1 1 0 1 1 1 0 TMEM154 protein family Choline_transpo PF04515.7 KFO98673.1 - 1.5e-87 293.4 29.9 1.5e-87 293.4 20.7 2.2 3 0 0 3 3 3 1 Plasma-membrane choline transporter Calponin PF00402.13 KFO98674.1 - 2.5e-39 132.2 13.0 3.8e-14 51.6 0.8 3.6 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.26 KFO98674.1 - 9.2e-17 61.0 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFO98674.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.6 KFO98674.1 - 0.11 12.5 0.1 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin Alg14 PF08660.6 KFO98675.1 - 4.3e-62 209.0 0.0 4.8e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TRAM_LAG1_CLN8 PF03798.11 KFO98676.1 - 1.2e-40 139.1 14.0 1.8e-40 138.6 9.7 1.2 1 0 0 1 1 1 1 TLC domain DUF3007 PF11460.3 KFO98676.1 - 0.056 13.5 1.8 0.2 11.7 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3007) Cyto_heme_lyase PF01265.12 KFO98677.1 - 1.9e-90 302.9 5.1 2.7e-90 302.4 3.5 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase RWD PF05773.17 KFO98678.1 - 1.3e-12 47.6 0.1 2.9e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.7 KFO98678.1 - 6.8e-09 35.4 0.6 1.3e-08 34.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RRM_5 PF13893.1 KFO98679.1 - 1.5e-46 156.0 3.0 2.7e-13 49.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98679.1 - 2.4e-35 120.3 0.1 5e-09 36.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO98679.1 - 2.4e-30 103.9 0.2 4.3e-08 32.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DHO_dh PF01180.16 KFO98680.1 - 3.1e-34 118.2 0.0 1.3e-33 116.2 0.0 2.0 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.1 KFO98680.1 - 2.3e-27 94.7 1.2 2.3e-27 94.7 0.8 2.3 2 1 1 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.1 KFO98680.1 - 4.7e-23 80.7 12.3 4.7e-23 80.7 8.5 3.8 3 1 0 3 3 2 1 4Fe-4S dicluster domain NAD_binding_8 PF13450.1 KFO98680.1 - 5.4e-08 32.7 0.0 1.6e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFO98680.1 - 3e-07 30.5 0.0 0.27 11.1 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.12 KFO98680.1 - 1.1e-06 27.7 0.1 2.2e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Fer4_10 PF13237.1 KFO98680.1 - 1.8e-06 27.6 9.8 1.8e-06 27.6 6.8 3.4 3 2 0 3 3 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 KFO98680.1 - 2.1e-06 28.0 10.1 2.1e-06 28.0 7.0 3.6 4 0 0 4 4 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFO98680.1 - 0.0002 21.5 30.1 0.00063 19.9 9.0 3.1 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 KFO98680.1 - 0.00046 19.9 1.8 0.00046 19.9 1.2 4.3 4 1 0 4 4 3 2 4Fe-4S binding domain Pyr_redox PF00070.22 KFO98680.1 - 0.00057 20.2 1.4 1.8 9.0 0.0 3.4 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFO98680.1 - 0.0048 16.9 0.0 4.7 7.2 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.22 KFO98680.1 - 0.005 16.3 4.6 0.005 16.3 3.2 5.5 6 0 0 6 6 6 2 4Fe-4S binding domain Fer4_2 PF12797.2 KFO98680.1 - 0.0087 15.9 13.0 0.014 15.2 1.6 4.5 4 0 0 4 4 3 2 4Fe-4S binding domain DAO PF01266.19 KFO98680.1 - 0.011 14.6 0.0 0.033 13.0 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KFO98680.1 - 0.012 14.7 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 KFO98680.1 - 0.028 14.5 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PcrB PF01884.12 KFO98680.1 - 0.044 13.0 0.0 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 PcrB family Fer4_15 PF13459.1 KFO98680.1 - 0.054 14.0 9.3 0.95 10.0 0.4 3.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain FAD_binding_2 PF00890.19 KFO98680.1 - 0.13 11.1 0.8 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Fer4_8 PF13183.1 KFO98680.1 - 0.49 10.4 29.6 0.036 14.1 2.8 3.9 2 2 1 3 3 3 0 4Fe-4S dicluster domain PX PF00787.19 KFO98681.1 - 2.8e-25 88.3 1.4 7e-25 87.0 0.4 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KFO98681.1 - 7.1e-05 22.1 6.8 0.0082 15.4 0.1 2.5 2 1 1 3 3 3 2 Vps5 C terminal like KIF1B PF12423.3 KFO98681.1 - 2.4 8.2 4.8 13 5.9 0.3 3.0 4 0 0 4 4 4 0 Kinesin protein 1B PAP2 PF01569.16 KFO98682.1 - 1.8e-16 60.0 2.5 2.5e-16 59.5 1.7 1.1 1 0 0 1 1 1 1 PAP2 superfamily Cyto_ox_2 PF02322.10 KFO98682.1 - 0.0018 17.4 1.0 0.0028 16.9 0.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase subunit II SLAC1 PF03595.12 KFO98682.1 - 0.0044 15.7 0.6 0.0068 15.0 0.4 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel Syndecan PF01034.15 KFO98682.1 - 0.059 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain YjgP_YjgQ PF03739.9 KFO98682.1 - 0.078 11.6 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF998 PF06197.8 KFO98682.1 - 0.11 11.8 4.3 0.086 12.1 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF998) DUF1191 PF06697.7 KFO98682.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PAP2 PF01569.16 KFO98683.1 - 2.2e-14 53.2 1.2 3.5e-14 52.5 0.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PTH2 PF01981.11 KFO98683.1 - 0.18 11.4 0.8 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Peptidyl-tRNA hydrolase PTH2 Paralemmin PF03285.10 KFO98684.1 - 7e-24 84.7 21.7 5.8e-12 45.6 0.3 3.2 2 2 0 2 2 2 2 Paralemmin PilJ PF13675.1 KFO98684.1 - 0.016 15.5 1.2 0.051 13.8 0.8 1.8 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3573 PF12097.3 KFO98684.1 - 0.72 8.3 1.8 1.2 7.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Nup54 PF13874.1 KFO98684.1 - 0.89 9.2 16.2 1.9 8.1 9.0 2.8 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.14 KFO98684.1 - 2.1 6.1 8.8 3.2 5.5 6.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reeler PF02014.11 KFO98685.1 - 3.4e-32 111.4 0.0 5.3e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Reeler domain DOMON PF03351.12 KFO98685.1 - 4.1e-19 68.7 0.0 8.8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 KFO98685.1 - 0.0028 17.5 8.3 0.0067 16.2 5.8 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 KFO98685.1 - 0.096 12.4 6.1 0.13 11.9 2.4 2.2 1 1 1 2 2 2 0 Tight junction protein, Claudin-like hDGE_amylase PF14701.1 KFO98686.1 - 2.8e-168 560.2 0.1 3.8e-168 559.7 0.1 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KFO98686.1 - 3.1e-127 424.3 0.0 5.2e-127 423.6 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KFO98686.1 - 4e-87 291.6 0.0 5.8e-87 291.1 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KFO98686.1 - 8.2e-25 86.4 0.0 1.6e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KFO98686.1 - 1.6e-05 24.4 0.1 6.9e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Nuc_sug_transp PF04142.10 KFO98687.1 - 5.5e-103 343.2 13.3 9.8e-103 342.4 9.2 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KFO98687.1 - 1.3e-08 34.0 13.3 1.8e-08 33.6 9.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFO98687.1 - 7.3e-07 29.2 1.8 7.3e-07 29.2 1.3 3.2 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 KFO98687.1 - 1.5e-06 27.8 19.7 1.3e-05 24.8 1.2 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KFO98687.1 - 0.00016 21.8 3.5 0.00016 21.8 2.4 3.5 1 1 2 3 3 3 1 Multidrug resistance efflux transporter DUF165 PF02592.10 KFO98687.1 - 0.023 14.9 2.3 0.023 14.9 1.6 2.8 3 0 0 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 Ubiq-Cytc-red_N PF09165.5 KFO98687.1 - 0.17 12.2 0.2 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal DUF4131 PF13567.1 KFO98687.1 - 7.4 5.9 13.6 5.2 6.4 1.9 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 KFO98688.1 - 1.3e-33 116.1 38.2 3.2e-32 111.6 26.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Tropomyosin_1 PF12718.2 KFO98689.1 - 0.0029 17.4 16.3 0.0029 17.4 11.3 4.9 1 1 4 5 5 5 2 Tropomyosin like Spc42p PF11544.3 KFO98689.1 - 0.011 15.6 6.1 0.011 15.6 4.2 5.6 2 2 4 6 6 6 0 Spindle pole body component Spc42p DUF641 PF04859.7 KFO98689.1 - 0.012 15.4 6.6 0.012 15.4 4.5 5.6 1 1 4 5 5 5 0 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 KFO98689.1 - 0.13 11.4 21.6 0.063 12.4 4.2 3.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 KFO98689.1 - 1.6 8.2 80.1 0.16 11.5 19.9 4.3 1 1 3 4 4 4 0 IncA protein IFT57 PF10498.4 KFO98689.1 - 2.2 6.9 62.9 0.38 9.4 17.5 3.2 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 TRM13 PF05206.9 KFO98690.1 - 1.1e-91 306.6 3.6 1.6e-91 306.1 2.5 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 KFO98690.1 - 3.1e-13 48.8 2.5 3.1e-13 48.8 1.8 2.8 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 KFO98690.1 - 6.5e-11 41.6 2.0 1.5e-10 40.5 1.4 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 KFO98690.1 - 0.00061 19.4 4.6 0.00082 19.0 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.12 KFO98690.1 - 0.016 14.6 0.0 0.062 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase LRR_4 PF12799.2 KFO98691.1 - 2.8e-37 125.7 38.5 4.5e-13 48.5 1.4 6.9 3 1 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO98691.1 - 1.8e-34 117.2 25.8 7.4e-13 48.0 1.1 4.3 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KFO98691.1 - 4.2e-22 74.7 21.2 0.034 14.1 0.0 8.9 9 0 0 9 9 9 6 Leucine Rich Repeat LRR_6 PF13516.1 KFO98691.1 - 2.2e-12 45.6 16.1 0.053 13.6 0.3 7.4 7 1 1 8 8 8 5 Leucine Rich repeat LRR_7 PF13504.1 KFO98691.1 - 2.5e-12 44.8 17.1 0.41 11.0 0.0 8.4 9 0 0 9 9 9 4 Leucine rich repeat LRR_9 PF14580.1 KFO98691.1 - 0.00026 20.5 4.2 0.15 11.5 0.1 2.6 1 1 2 3 3 3 2 Leucine-rich repeat SPATA19 PF15212.1 KFO98691.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial LRR_3 PF07725.7 KFO98691.1 - 0.2 11.4 4.2 19 5.2 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat 2-oxoacid_dh PF00198.18 KFO98692.1 - 1.7e-79 266.3 0.0 2.3e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFO98692.1 - 1.1e-17 63.3 0.0 2e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KFO98692.1 - 5.2e-14 51.5 0.0 1.2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KFO98692.1 - 0.051 13.2 0.0 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like HTH_17 PF12728.2 KFO98692.1 - 0.15 12.2 0.0 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain RTC PF01137.16 KFO98693.1 - 8e-75 250.5 0.2 1e-74 250.1 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KFO98693.1 - 2.8e-24 85.1 0.1 5.1e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain 7tm_1 PF00001.16 KFO98694.1 - 4.1e-16 58.9 0.9 5.1e-16 58.5 0.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFO98694.1 - 2.4e-08 33.4 1.0 3.2e-08 33.0 0.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 KFO98694.1 - 0.0028 16.8 1.1 0.0039 16.3 0.8 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DSPn PF14671.1 KFO98695.1 - 7.1e-60 201.0 3.5 1.6e-59 199.9 1.2 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KFO98695.1 - 4.8e-15 55.3 0.0 2e-14 53.3 0.0 2.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFO98695.1 - 4e-06 26.9 0.0 8.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFO98695.1 - 1.6e-05 24.3 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFO98695.1 - 0.00055 20.2 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Glyco_transf_64 PF09258.5 KFO98696.1 - 2.4e-84 282.3 0.0 2.9e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.21 KFO98696.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 TP_methylase PF00590.15 KFO98697.1 - 1.4e-20 73.8 0.0 2.9e-20 72.9 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TLV_coat PF00429.14 KFO98698.1 - 0.11 10.8 0.2 0.11 10.8 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) rve PF00665.21 KFO98699.1 - 1.1e-28 99.7 0.1 1.9e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.19 KFO98699.1 - 6e-13 49.2 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 RNase H Integrase_Zn PF02022.14 KFO98699.1 - 3.1e-10 39.3 0.4 6.4e-10 38.3 0.3 1.6 1 0 0 1 1 1 1 Integrase Zinc binding domain DDE_Tnp_IS240 PF13610.1 KFO98699.1 - 2.9e-05 24.0 0.0 5.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.1 KFO98699.1 - 0.0048 16.3 0.0 0.015 14.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain UCR_UQCRX_QCR9 PF05365.7 KFO98699.1 - 0.025 14.1 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like dUTPase PF00692.14 KFO98700.1 - 2e-19 69.3 0.0 2.8e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFO98700.1 - 4.2e-05 23.4 0.1 0.00019 21.2 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KFO98700.1 - 0.00028 20.6 0.5 0.0084 15.9 0.1 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ArgJ PF01960.13 KFO98700.1 - 0.12 10.7 0.2 1.1 7.6 0.1 1.9 1 1 1 2 2 2 0 ArgJ family OLF PF02191.11 KFO98701.1 - 8.7e-92 306.9 8.4 1.3e-91 306.3 5.8 1.3 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 KFO98701.1 - 1.3e-50 169.3 2.7 1.3e-50 169.3 1.9 1.9 3 0 0 3 3 3 1 Neurogenesis glycoprotein CBM_5_12_2 PF14600.1 KFO98701.1 - 0.05 13.2 1.1 0.98 9.1 0.0 2.7 2 0 0 2 2 2 0 Cellulose-binding domain Pox_A_type_inc PF04508.7 KFO98701.1 - 0.14 11.9 0.9 0.67 9.8 0.6 2.2 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Phage_head_chap PF11113.3 KFO98701.1 - 2.6 7.9 5.4 25 4.8 0.0 3.7 4 0 0 4 4 4 0 Head assembly gene product DUF1664 PF07889.7 KFO98701.1 - 3.7 7.3 6.4 4.3 7.1 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Collagen PF01391.13 KFO98702.1 - 2.6e-156 507.2 668.5 5.3e-10 38.7 16.0 22.0 5 3 11 16 16 16 14 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFO98702.1 - 5.7e-85 284.0 0.1 1e-84 283.2 0.1 1.4 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.19 KFO98702.1 - 8.7e-12 45.1 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFO98702.1 - 3.4e-07 30.6 0.0 6.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 KFO98702.1 - 0.0058 16.6 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Sp100 PF03172.8 KFO98703.1 - 3e-24 84.9 0.0 4.6e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Sp100 domain PHD PF00628.24 KFO98703.1 - 3.9e-09 36.0 9.5 3.9e-09 36.0 6.6 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 KFO98703.1 - 0.03 14.4 4.1 0.081 13.0 2.8 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Aminotran_5 PF00266.14 KFO98704.1 - 2.5e-37 128.4 0.0 3.9e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V EamA PF00892.15 KFO98705.1 - 6.1e-17 61.8 26.1 2.4e-09 37.3 9.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KFO98705.1 - 0.0055 15.6 18.0 0.011 14.6 12.2 1.6 1 1 0 1 1 1 1 UAA transporter family IRK PF01007.15 KFO98706.1 - 1.8e-88 296.5 0.0 2.1e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFO98706.1 - 0.00027 20.6 3.5 0.00054 19.6 2.4 1.5 1 1 0 1 1 1 1 Ion channel DUF3324 PF11797.3 KFO98706.1 - 0.12 12.1 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) HpaP PF09483.5 KFO98707.1 - 0.023 14.6 0.2 0.025 14.5 0.1 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) RhoGEF PF00621.15 KFO98708.1 - 1.1e-37 129.5 9.1 2.3e-37 128.6 6.3 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 KFO98708.1 - 1.9e-12 46.3 0.0 5.7e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFO98708.1 - 1.5e-11 43.6 0.1 3.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO98708.1 - 2.1e-07 30.3 0.0 4.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFO98708.1 - 0.00057 20.0 0.8 0.0023 18.1 0.0 2.3 2 1 0 2 2 2 1 PH domain BNR_2 PF13088.1 KFO98709.1 - 6.1e-30 104.4 0.0 7.7e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KFO98709.1 - 0.0043 16.6 5.4 0.22 11.4 0.2 3.5 4 0 0 4 4 4 2 BNR/Asp-box repeat ATG16 PF08614.6 KFO98710.1 - 2e-56 190.9 25.5 2e-56 190.9 17.7 1.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.27 KFO98710.1 - 3.4e-42 140.8 16.1 1.3e-09 37.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFO98710.1 - 1.3e-05 24.9 0.0 0.89 9.2 0.0 3.5 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFO98710.1 - 0.00037 18.7 6.9 1.2 7.2 0.0 4.3 2 1 2 5 5 5 3 Nucleoporin Nup120/160 DUF4200 PF13863.1 KFO98710.1 - 0.011 15.7 22.9 0.011 15.7 15.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 KFO98710.1 - 0.014 15.6 8.2 0.014 15.6 5.7 3.7 2 1 2 4 4 3 0 Protein of unknown function (DUF904) ERM PF00769.14 KFO98710.1 - 0.049 13.1 33.0 0.011 15.2 20.3 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HTH_6 PF01418.12 KFO98710.1 - 0.07 12.8 0.9 0.19 11.4 0.6 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family V_ATPase_I PF01496.14 KFO98710.1 - 0.13 10.0 14.4 0.18 9.5 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CALCOCO1 PF07888.6 KFO98710.1 - 0.14 10.4 18.2 0.25 9.5 12.6 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 KFO98710.1 - 0.3 10.2 2.3 0.53 9.4 1.6 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Synaptobrevin PF00957.16 KFO98710.1 - 0.63 9.6 5.6 2.1 7.9 3.4 2.2 2 0 0 2 2 2 0 Synaptobrevin DUF641 PF04859.7 KFO98710.1 - 0.94 9.2 14.0 0.1 12.3 3.7 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TBPIP PF07106.8 KFO98710.1 - 1.2 8.6 24.8 0.015 14.8 9.7 2.3 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 KFO98710.1 - 1.2 9.4 5.1 0.61 10.3 0.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 KFO98710.1 - 1.5 9.2 22.7 0.17 12.2 5.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 KFO98710.1 - 1.6 8.5 7.2 4.4 7.1 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 KFO98710.1 - 2.3 7.4 8.4 3.3 6.9 5.0 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein IncA PF04156.9 KFO98710.1 - 3.2 7.3 35.8 0.17 11.4 13.5 2.3 1 1 1 2 2 2 0 IncA protein BLOC1_2 PF10046.4 KFO98710.1 - 4.1 7.6 17.8 0.2 11.8 3.0 3.1 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 KFO98710.1 - 8.9 6.2 8.2 0.28 11.1 0.8 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 KFO98710.1 - 9.3 6.7 18.0 0.24 11.8 3.1 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Arrestin_N PF00339.24 KFO98711.1 - 2.2e-37 128.1 0.0 2.1e-33 115.2 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFO98711.1 - 5.9e-25 87.9 0.5 8.8e-25 87.3 0.4 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Gryzun PF07919.7 KFO98711.1 - 0.016 13.5 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi Transglut_C PF00927.17 KFO98711.1 - 0.048 13.6 0.5 0.16 11.9 0.4 1.8 1 1 1 2 2 2 0 Transglutaminase family, C-terminal ig like domain LDB19 PF13002.2 KFO98711.1 - 0.069 12.6 0.0 8.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Arrestin_N terminal like DUF2079 PF09852.4 KFO98711.1 - 0.076 11.7 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DAGK_acc PF00609.14 KFO98712.1 - 1e-52 178.5 0.0 2.1e-52 177.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFO98712.1 - 1.1e-29 102.4 0.0 2.4e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFO98712.1 - 3.7e-20 71.4 25.0 1.5e-11 43.8 3.8 2.8 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFO98712.1 - 3.6e-16 59.2 0.2 9.3e-16 57.9 0.2 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KFO98712.1 - 5.6e-12 45.3 0.6 2.9e-11 43.0 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFO98712.1 - 2.3e-11 43.6 1.4 3e-10 40.1 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KFO98712.1 - 3e-07 30.6 4.8 2e-06 28.0 1.1 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFO98712.1 - 0.00013 21.9 0.2 0.0003 20.7 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain C1_3 PF07649.7 KFO98712.1 - 0.0062 16.5 2.8 0.0062 16.5 2.0 3.1 2 1 0 2 2 2 1 C1-like domain Mcp5_PH PF12814.2 KFO98712.1 - 0.023 14.6 0.1 0.065 13.1 0.1 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Trypsin PF00089.21 KFO98713.1 - 3.9e-63 212.9 0.0 4.3e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFO98713.1 - 1.3e-07 31.1 0.0 2.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFO98713.1 - 6.1e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Carboxyl_trans PF01039.17 KFO98714.1 - 5.8e-141 470.2 0.0 6.4e-141 470.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain EF-hand_7 PF13499.1 KFO98716.1 - 2e-20 72.7 1.2 1.1e-16 60.6 0.7 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFO98716.1 - 7.8e-06 25.3 0.1 0.16 11.9 0.0 4.8 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.27 KFO98716.1 - 1.7e-05 23.8 0.1 0.036 13.3 0.0 4.3 5 0 0 5 5 5 1 EF hand EF-hand_5 PF13202.1 KFO98716.1 - 3.8e-05 22.8 0.0 0.0013 17.9 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFO98716.1 - 0.00048 19.6 0.2 2.5 7.7 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO98716.1 - 0.018 15.0 1.0 7.1 6.6 0.0 2.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4187 PF13821.1 KFO98716.1 - 0.048 13.2 0.7 0.12 11.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DBR1 PF05011.8 KFO98717.1 - 5.6e-39 133.3 0.5 1e-38 132.4 0.3 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KFO98717.1 - 4.8e-18 65.2 0.5 7.7e-18 64.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFO98717.1 - 1.2e-05 25.1 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arm PF00514.18 KFO98718.1 - 3e-21 74.4 23.8 6.5e-05 22.6 0.1 11.1 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFO98718.1 - 1.3e-18 67.0 2.1 0.0054 16.9 0.0 7.8 3 2 5 9 9 9 7 HEAT repeats HEAT PF02985.17 KFO98718.1 - 8.3e-13 47.2 12.8 0.018 15.0 0.0 8.7 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 KFO98718.1 - 9.9e-07 29.0 1.8 8.8 6.9 0.0 7.0 5 2 2 7 7 7 2 HEAT-like repeat V-ATPase_H_C PF11698.3 KFO98718.1 - 6.3e-05 22.8 7.6 3.2 7.6 0.5 5.3 3 1 1 5 5 5 2 V-ATPase subunit H ParcG PF10274.4 KFO98718.1 - 0.0058 16.5 2.7 0.8 9.5 0.2 3.7 2 1 0 3 3 3 1 Parkin co-regulated protein Thioredoxin PF00085.15 KFO98719.1 - 1.1e-06 28.2 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin 3HCDH_N PF02737.13 KFO98721.1 - 7.9e-52 175.5 0.7 1.1e-51 175.0 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFO98721.1 - 7.9e-29 99.9 0.0 2e-25 89.0 0.0 3.0 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFO98721.1 - 0.00067 19.5 0.1 0.0019 18.0 0.1 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFO98721.1 - 0.0025 18.1 0.0 0.0059 17.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KFO98721.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ECH PF00378.15 KFO98722.1 - 3.7e-56 189.9 0.4 4e-56 189.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFO98722.1 - 4.9e-06 26.4 0.0 0.052 13.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Pkinase_Tyr PF07714.12 KFO98723.1 - 1.8e-64 217.3 0.0 2.7e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO98723.1 - 4.7e-60 202.9 0.0 9.1e-60 201.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HAUS-augmin3 PF14932.1 KFO98723.1 - 0.01 15.0 2.0 0.029 13.5 1.4 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Kinase-like PF14531.1 KFO98723.1 - 0.02 13.8 0.0 0.044 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFO98723.1 - 0.04 13.6 0.0 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family IFT57 PF10498.4 KFO98723.1 - 0.18 10.5 5.5 0.066 11.9 1.8 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 SNARE_assoc PF09335.6 KFO98725.1 - 6.4e-20 71.5 4.0 6.4e-20 71.5 2.8 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein Lipase PF00151.14 KFO98726.1 - 4.1e-78 262.8 0.0 5.9e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFO98726.1 - 5.3e-05 23.2 0.0 7.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Apc13p PF05839.6 KFO98727.1 - 3e-20 71.9 0.3 4.1e-20 71.5 0.2 1.2 1 0 0 1 1 1 1 Apc13p protein Tup_N PF08581.5 KFO98728.1 - 0.012 15.7 8.5 0.012 15.7 5.9 6.5 5 3 0 6 6 6 0 Tup N-terminal Reo_sigmaC PF04582.7 KFO98728.1 - 8.1 5.5 26.2 0.42 9.7 3.4 3.9 1 1 3 5 5 5 0 Reovirus sigma C capsid protein Transglut_core PF01841.14 KFO98729.1 - 3.9e-13 49.5 0.0 7.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KFO98729.1 - 0.0013 18.0 0.2 0.0066 15.7 0.2 2.1 1 1 0 1 1 1 1 Transglutaminase-like domain Pkinase_Tyr PF07714.12 KFO98730.1 - 5.2e-99 330.5 0.0 6e-99 330.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO98730.1 - 2.4e-50 171.1 0.0 2.9e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFO98730.1 - 3.2e-14 53.0 1.1 5.6e-14 52.3 0.8 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain ABC1 PF03109.11 KFO98730.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Gb3_synth PF04572.7 KFO98731.1 - 5.9e-45 152.2 1.6 9e-45 151.6 1.1 1.3 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.10 KFO98731.1 - 5.8e-20 71.6 0.0 1.5e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFO98731.1 - 0.046 12.1 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PMP22_Claudin PF00822.15 KFO98732.1 - 2e-30 105.6 14.0 2.7e-30 105.2 9.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO98732.1 - 2.2e-16 60.0 11.3 3.3e-16 59.4 7.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF308 PF03729.8 KFO98732.1 - 0.0016 18.3 15.6 0.053 13.5 5.9 3.0 3 0 0 3 3 3 2 Short repeat of unknown function (DUF308) Amastin PF07344.6 KFO98732.1 - 0.053 13.1 11.6 0.045 13.3 6.7 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF2530 PF10745.4 KFO98732.1 - 0.078 12.9 1.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4064 PF13273.1 KFO98732.1 - 0.18 11.9 12.5 0.18 11.9 3.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DoxX PF07681.7 KFO98732.1 - 0.19 12.1 6.4 0.4 11.1 1.3 2.3 2 0 0 2 2 2 0 DoxX DUF1218 PF06749.7 KFO98732.1 - 0.61 10.5 6.6 0.87 10.0 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Trp_oprn_chp PF09534.5 KFO98732.1 - 0.63 9.6 4.7 6.8 6.2 3.3 2.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1469 PF07332.6 KFO98732.1 - 1.3 8.7 20.4 0.22 11.2 5.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) TMEM171 PF15471.1 KFO98732.1 - 5.9 5.5 8.1 15 4.2 5.5 1.7 1 1 0 1 1 1 0 Transmembrane protein family 171 HMG_box PF00505.14 KFO98733.1 - 6.8e-28 96.7 4.8 6.8e-28 96.7 3.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO98733.1 - 3.9e-12 46.3 2.8 7.1e-12 45.5 1.9 1.4 1 0 0 1 1 1 1 HMG-box domain SOXp PF12336.3 KFO98733.1 - 4.6e-05 23.9 4.1 7.8e-05 23.2 0.2 2.7 3 1 0 3 3 3 1 SOX transcription factor Crystall PF00030.14 KFO98734.1 - 1.8e-59 197.6 1.0 1.4e-28 98.5 0.0 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFO98734.1 - 1.9e-06 27.4 0.1 0.37 10.5 0.0 3.6 3 1 1 4 4 4 3 Beta/Gamma crystallin TBCC PF07986.7 KFO98735.1 - 3.9e-33 113.3 0.1 7.4e-33 112.4 0.1 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 KFO98735.1 - 2.1e-05 23.9 0.4 3.9e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CTDII PF01556.13 KFO98736.1 - 4.4e-30 103.4 3.1 2.1e-25 88.4 0.1 3.5 4 0 0 4 4 4 2 DnaJ C terminal domain DnaJ PF00226.26 KFO98736.1 - 4.8e-29 99.8 1.3 7.3e-29 99.2 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain MHC_I PF00129.13 KFO98737.1 - 8.9e-07 28.4 0.1 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 PFK PF00365.15 KFO98738.1 - 1.9e-186 617.6 7.6 1.2e-124 414.9 1.4 2.0 2 0 0 2 2 2 2 Phosphofructokinase LRR_4 PF12799.2 KFO98739.1 - 5e-17 61.0 11.3 4.5e-10 38.9 2.5 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO98739.1 - 1.9e-08 33.9 4.2 4.4e-07 29.5 1.5 2.5 2 0 0 2 2 2 1 Leucine rich repeat SART-1 PF03343.8 KFO98739.1 - 1.4e-05 23.6 0.3 1.8e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 SART-1 family LRR_9 PF14580.1 KFO98739.1 - 2.2e-05 24.0 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KFO98739.1 - 0.00076 19.2 5.8 0.13 12.3 1.0 4.2 4 0 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 KFO98739.1 - 0.0023 17.8 3.5 0.36 11.2 0.5 3.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KFO98739.1 - 0.0041 16.9 6.8 0.33 11.1 1.1 3.7 3 0 0 3 3 3 2 Leucine Rich Repeat KH_1 PF00013.24 KFO98740.1 - 1.4e-56 187.9 12.6 8.1e-15 54.2 0.1 4.5 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 KFO98740.1 - 4e-38 128.4 14.6 1.3e-09 37.5 0.2 5.1 5 0 0 5 5 5 4 KH domain KH_2 PF07650.12 KFO98740.1 - 1.7e-16 59.5 10.9 0.00031 20.2 0.1 4.8 5 0 0 5 5 5 4 KH domain KH_4 PF13083.1 KFO98740.1 - 7.4e-15 54.3 3.2 0.0013 18.3 0.0 4.9 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.17 KFO98740.1 - 1.3e-07 31.1 0.0 2.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.1 KFO98740.1 - 5.4e-07 29.3 4.3 0.29 10.9 0.0 4.6 4 0 0 4 4 4 3 NusA-like KH domain RRM_5 PF13893.1 KFO98740.1 - 1.2e-05 25.0 0.1 4.6e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98740.1 - 3.5e-05 23.6 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_C48 PF02902.14 KFO98741.1 - 8.3e-42 143.2 1.6 1.1e-41 142.7 1.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 KFO98741.1 - 2.2e-05 23.1 0.4 0.00066 18.3 0.0 2.1 2 0 0 2 2 2 2 Vaccinia virus I7 processing peptidase Angiomotin_C PF12240.3 KFO98742.1 - 9.8e-94 312.6 9.1 9.8e-94 312.6 6.3 3.1 2 1 0 2 2 2 1 Angiomotin C terminal HALZ PF02183.13 KFO98742.1 - 0.0038 16.9 1.2 0.0038 16.9 0.8 5.3 6 0 0 6 6 6 1 Homeobox associated leucine zipper SBP_bac_7 PF03480.8 KFO98742.1 - 0.0061 15.7 4.2 0.53 9.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein, family 7 Tht1 PF04163.7 KFO98742.1 - 0.056 11.8 5.3 0.09 11.1 3.7 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Pkinase_Tyr PF07714.12 KFO98743.1 - 1.2e-80 270.3 0.0 1.6e-80 269.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO98743.1 - 1.2e-31 109.8 0.2 2e-31 109.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain WIF PF02019.13 KFO98743.1 - 3e-16 59.0 0.1 6.3e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 WIF domain Shisa PF13908.1 KFO98743.1 - 0.0012 19.1 0.5 0.0021 18.2 0.3 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LIM PF00412.17 KFO98744.1 - 2.4e-61 203.6 59.7 2.5e-14 53.0 2.3 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.16 KFO98745.1 - 5.5e-54 182.9 17.6 7.7e-54 182.5 12.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO98745.1 - 6.2e-07 28.8 17.1 7.5e-07 28.5 11.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFO98745.1 - 0.00012 21.2 14.6 0.00012 21.2 10.1 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.16 KFO98745.1 - 0.05 13.0 19.6 0.05 13.0 12.9 1.5 1 1 0 1 1 1 0 Srg family chemoreceptor 7TM_GPCR_Srx PF10328.4 KFO98745.1 - 0.12 11.4 20.4 0.01 14.9 6.7 2.8 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx SdpI PF13630.1 KFO98745.1 - 0.8 9.4 9.2 2.7e+02 1.3 0.0 3.9 2 1 0 2 2 2 0 SdpI/YhfL protein family Sigma_reg_N PF13800.1 KFO98745.1 - 1.7 8.7 4.4 1.3 9.1 1.2 2.3 1 1 0 1 1 1 0 Sigma factor regulator N-terminal WD40 PF00400.27 KFO98746.1 - 2.1e-49 163.7 10.6 5.2e-09 35.6 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Collagen PF01391.13 KFO98746.1 - 5e-06 25.9 88.1 9.4e-05 21.8 21.2 9.9 6 1 3 9 9 9 3 Collagen triple helix repeat (20 copies) eIF2A PF08662.6 KFO98746.1 - 1.6e-05 24.7 3.0 0.088 12.5 0.5 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpb4 PF03874.11 KFO98747.1 - 7.1e-29 100.1 5.4 8e-29 100.0 3.8 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rop PF01815.11 KFO98747.1 - 0.00038 19.8 0.8 0.00097 18.5 0.6 1.6 1 0 0 1 1 1 1 Rop protein Maelstrom PF13017.1 KFO98747.1 - 0.045 13.2 0.3 0.048 13.1 0.2 1.0 1 0 0 1 1 1 0 piRNA pathway germ-plasm component Birna_VP5 PF03042.9 KFO98747.1 - 0.052 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP5 protein AMMECR1 PF01871.12 KFO98748.1 - 4.6e-45 152.8 0.0 6.2e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 UDP-g_GGTase PF06427.6 KFO98750.1 - 1.4e-78 263.0 0.4 7.5e-77 257.3 0.0 2.9 3 0 0 3 3 3 2 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KFO98750.1 - 6.6e-07 28.9 0.6 6.6e-07 28.9 0.4 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 8 Lipase_GDSL_2 PF13472.1 KFO98751.1 - 0.0012 19.0 0.0 0.0042 17.2 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Stn1 PF10451.4 KFO98751.1 - 0.074 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 PID_2 PF14719.1 KFO98752.1 - 2.2e-18 66.5 0.5 3.8e-18 65.7 0.4 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.18 KFO98752.1 - 1.3e-06 28.4 1.5 1.9e-06 27.8 1.0 1.5 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) HECT PF00632.20 KFO98753.1 - 1.1e-93 313.8 0.7 2.5e-93 312.7 0.0 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) WWE PF02825.15 KFO98753.1 - 0.00028 20.2 0.1 0.00077 18.8 0.1 1.8 1 0 0 1 1 1 1 WWE domain MFS_1 PF07690.11 KFO98754.1 - 1.9e-50 171.5 34.8 5.7e-40 137.1 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 KFO98754.1 - 2.7 8.1 0.0 2.7 8.1 0.0 4.0 3 2 0 4 4 4 0 NfeD-like C-terminal, partner-binding zf-H2C2_2 PF13465.1 KFO98755.1 - 5.4e-26 89.5 78.6 3.8e-06 26.9 4.2 12.3 11 1 1 12 12 12 7 Zinc-finger double domain BTB PF00651.26 KFO98755.1 - 7.3e-22 77.4 0.1 1.8e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFO98755.1 - 4.7e-21 73.7 83.5 2.9e-05 24.1 1.2 11.8 11 0 0 11 11 11 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFO98755.1 - 8.9e-12 44.7 47.9 0.00016 21.7 0.0 9.8 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFO98755.1 - 1.2e-11 44.0 81.9 0.038 14.3 1.6 11.9 11 0 0 11 11 11 8 C2H2-type zinc finger zf-met PF12874.2 KFO98755.1 - 8e-06 25.8 0.3 8e-06 25.8 0.2 8.7 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFO98755.1 - 0.84 9.6 55.9 0.071 13.0 0.6 9.7 10 0 0 10 10 10 0 C2H2-type zinc finger zf-CHY PF05495.7 KFO98755.1 - 1.7 8.8 57.9 0.2 11.8 7.8 5.8 3 1 1 5 5 5 0 CHY zinc finger RasGAP PF00616.14 KFO98756.1 - 2.6e-41 141.4 0.2 1.4e-40 139.1 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KFO98756.1 - 8.3e-31 105.6 3.3 4.9e-16 58.3 0.8 3.3 2 1 0 2 2 2 2 C2 domain PH PF00169.24 KFO98756.1 - 2.7e-14 53.2 6.0 3.5e-14 52.8 0.4 2.6 2 0 0 2 2 2 1 PH domain BTK PF00779.14 KFO98756.1 - 2.4e-13 49.4 1.5 4.6e-13 48.5 1.0 1.5 1 0 0 1 1 1 1 BTK motif CEP76-C2 PF15627.1 KFO98756.1 - 0.00036 20.0 0.4 0.96 8.9 0.0 2.5 2 0 0 2 2 2 2 CEP76 C2 domain PH_8 PF15409.1 KFO98756.1 - 0.0044 17.0 0.6 0.013 15.5 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KFO98756.1 - 0.053 13.7 3.2 0.24 11.6 1.1 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain DNA_pol3_beta_2 PF02767.11 KFO98756.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain zf-rbx1 PF12678.2 KFO98757.1 - 5.1e-14 52.1 15.9 5.8e-14 51.9 11.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFO98757.1 - 1.3e-08 34.5 10.9 1.4e-08 34.4 7.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFO98757.1 - 2.2e-08 33.7 12.5 3.1e-08 33.2 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO98757.1 - 1.5e-05 24.5 9.7 2.2e-05 24.0 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO98757.1 - 0.0014 18.2 13.6 0.0028 17.2 9.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO98757.1 - 0.0016 18.4 12.3 0.0018 18.2 8.1 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO98757.1 - 0.0026 17.4 12.2 0.0043 16.7 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFO98757.1 - 0.028 14.2 4.8 0.035 13.8 3.3 1.1 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.9 KFO98757.1 - 0.046 13.2 0.2 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Zn_Tnp_IS1 PF03811.8 KFO98757.1 - 0.15 11.5 0.2 0.15 11.5 0.1 2.3 2 1 0 2 2 2 0 InsA N-terminal domain PHD PF00628.24 KFO98757.1 - 1.2 8.8 14.5 2.3 7.9 10.0 1.5 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 KFO98757.1 - 1.6 8.5 13.3 3.4 7.4 5.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KFO98757.1 - 2.9 7.5 13.3 1.5 8.4 7.9 1.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 KFO98758.1 - 9.4e-61 205.2 0.3 1.5e-60 204.5 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98758.1 - 3e-33 115.0 0.1 5.9e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFO98758.1 - 8.2e-15 54.9 2.8 8.2e-15 54.9 1.9 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.1 KFO98758.1 - 0.0025 16.8 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Na_K-ATPase PF00287.13 KFO98759.1 - 4.6e-86 288.1 1.4 2.5e-85 285.7 1.0 1.8 1 1 0 1 1 1 1 Sodium / potassium ATPase beta chain DP PF08781.5 KFO98760.1 - 3e-57 192.3 1.2 6.6e-57 191.2 0.9 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.15 KFO98760.1 - 4.1e-27 93.5 0.4 1e-26 92.2 0.3 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain AAA_23 PF13476.1 KFO98760.1 - 0.025 14.9 4.1 0.037 14.3 2.8 1.3 1 0 0 1 1 1 0 AAA domain FGGY_N PF00370.16 KFO98761.1 - 3.1e-39 134.7 0.0 1e-37 129.7 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KFO98761.1 - 1.6e-27 96.4 0.0 2.9e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain XRN_N PF03159.13 KFO98762.1 - 1.1e-103 345.7 0.1 2.4e-103 344.6 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PI3_PI4_kinase PF00454.22 KFO98763.1 - 5.7e-60 202.7 0.1 1.9e-59 200.9 0.1 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KFO98763.1 - 3.8e-46 157.6 3.3 3.8e-46 157.6 2.3 2.4 3 0 0 3 3 3 1 FAT domain UME PF08064.8 KFO98763.1 - 2.9e-27 94.7 0.2 2.9e-27 94.7 0.1 4.6 5 0 0 5 5 5 1 UME (NUC010) domain FATC PF02260.15 KFO98763.1 - 1.5e-12 46.7 0.1 3.4e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KFO98763.1 - 1.6e-08 33.9 5.8 0.1 12.6 0.0 8.3 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 KFO98763.1 - 1.1e-06 28.8 0.1 1.6 9.0 0.0 5.2 4 0 0 4 4 4 2 HEAT repeats Mad3_BUB1_I PF08311.7 KFO98763.1 - 0.033 13.9 3.0 0.13 12.0 0.1 3.4 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 HEAT_EZ PF13513.1 KFO98763.1 - 0.43 11.1 3.9 31 5.2 0.0 5.1 5 0 0 5 5 5 0 HEAT-like repeat CH PF00307.26 KFO98764.1 - 4.2e-79 261.5 1.0 9.4e-23 80.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFO98764.1 - 1.3e-11 44.4 0.0 4.2e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFO98764.1 - 1.9e-09 36.1 1.5 7.5e-06 24.8 0.1 3.0 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 KFO98764.1 - 1.3e-07 31.1 0.0 0.00011 21.7 0.0 3.6 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_8 PF13833.1 KFO98764.1 - 7.9e-05 22.1 0.7 0.0065 16.0 0.1 2.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFO98764.1 - 0.00022 20.8 0.2 0.16 11.9 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KFO98764.1 - 0.00052 19.2 2.5 0.0068 15.7 0.0 3.2 3 0 0 3 3 3 1 EF hand TRP_2 PF08344.6 KFO98765.1 - 2.7e-27 94.4 2.6 6.2e-27 93.3 1.8 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.26 KFO98765.1 - 1.8e-20 73.0 15.2 6e-20 71.3 10.2 2.1 3 0 0 3 3 3 1 Ion transport protein Ank_2 PF12796.2 KFO98765.1 - 7.1e-08 32.6 1.0 2.8e-05 24.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO98765.1 - 2.4e-06 27.9 0.3 0.021 15.3 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFO98765.1 - 0.0011 18.7 0.2 0.48 10.3 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KFO98765.1 - 0.004 17.3 0.1 2 8.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF2407_C PF13373.1 KFO98765.1 - 0.0096 15.8 0.1 0.089 12.7 0.0 2.6 2 0 0 2 2 2 1 DUF2407 C-terminal domain CUB PF00431.15 KFO98766.1 - 3.9e-61 203.9 0.0 4.2e-30 104.0 0.0 2.3 2 0 0 2 2 2 2 CUB domain NTR PF01759.16 KFO98766.1 - 1.9e-15 56.3 0.8 2.8e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 UNC-6/NTR/C345C module CUB_2 PF02408.15 KFO98766.1 - 1.6e-08 34.1 0.1 0.0016 17.9 0.0 2.6 2 0 0 2 2 2 2 CUB-like domain TIMP PF00965.12 KFO98766.1 - 0.0015 18.2 0.3 0.0028 17.3 0.2 1.4 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase HlyIII PF03006.15 KFO98767.1 - 2.5e-21 76.1 8.7 2.5e-21 76.1 6.0 1.4 2 0 0 2 2 2 1 Haemolysin-III related Surp PF01805.15 KFO98768.1 - 2e-20 72.1 0.1 6.6e-20 70.5 0.1 2.0 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 KFO98768.1 - 7.6e-15 54.3 0.0 1.7e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98768.1 - 3.1e-10 39.8 0.0 7.7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.7 KFO98768.1 - 5e-09 35.8 4.1 5e-09 35.8 2.8 3.3 3 0 0 3 3 3 1 cwf21 domain CTK3 PF12243.3 KFO98768.1 - 4.3e-05 23.1 0.2 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 RRM_5 PF13893.1 KFO98768.1 - 0.00022 20.9 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KFO98768.1 - 0.0066 16.6 0.5 0.05 13.8 0.1 2.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Sulfotransfer_1 PF00685.22 KFO98769.1 - 1.3e-13 50.8 0.0 1.5e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Na_H_Exchanger PF00999.16 KFO98770.1 - 1.9e-78 263.6 31.4 1.9e-77 260.3 21.8 2.1 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Cpn60_TCP1 PF00118.19 KFO98771.1 - 3.1e-21 75.5 0.0 3.2e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-H2C2_2 PF13465.1 KFO98772.1 - 2.5e-14 52.7 9.0 2.3e-08 33.8 0.9 4.9 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO98772.1 - 1.8e-13 49.9 17.4 3.3e-05 23.9 2.2 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO98772.1 - 2.2e-05 24.4 28.6 0.00057 20.0 1.9 4.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO98772.1 - 0.0024 17.7 5.5 0.15 11.9 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3446 PF11928.3 KFO98772.1 - 0.006 16.7 1.8 0.0086 16.2 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3446) zf-C2HC_2 PF13913.1 KFO98772.1 - 0.02 14.5 11.6 1.1 8.9 0.6 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RRN7 PF11781.3 KFO98772.1 - 0.039 13.4 5.2 0.05 13.1 0.2 2.9 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 KFO98772.1 - 0.25 11.5 3.2 2.4 8.4 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFO98772.1 - 0.31 10.8 10.8 9.5 6.0 7.5 2.9 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.2 KFO98772.1 - 0.71 10.1 8.9 0.51 10.6 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Reprolysin PF01421.14 KFO98777.1 - 7.1e-58 195.4 0.0 2e-57 194.0 0.0 1.8 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFO98777.1 - 1.2e-30 105.9 10.2 1.2e-30 105.9 7.1 3.6 3 1 0 3 3 1 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 KFO98777.1 - 4.2e-30 104.2 0.7 6.9e-30 103.5 0.5 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFO98777.1 - 3e-25 88.2 26.8 3e-25 88.2 18.6 4.7 3 1 0 3 3 1 1 Disintegrin Reprolysin_5 PF13688.1 KFO98777.1 - 2.1e-19 70.2 0.1 2.1e-19 70.2 0.0 2.0 2 0 0 2 2 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFO98777.1 - 1.9e-13 50.8 0.0 4.6e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFO98777.1 - 3.6e-12 46.8 0.0 1.3e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFO98777.1 - 7.6e-10 38.6 0.1 2.2e-09 37.1 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFO98777.1 - 0.00036 20.6 12.4 0.00036 20.6 8.6 5.5 6 1 1 7 7 2 1 EGF-like domain Peptidase_M43 PF05572.8 KFO98777.1 - 0.0073 15.9 2.4 0.54 9.8 0.1 2.9 3 0 0 3 3 3 1 Pregnancy-associated plasma protein-A Peptidase_M54 PF07998.6 KFO98777.1 - 0.034 13.8 0.3 0.094 12.4 0.2 1.7 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M10 PF00413.19 KFO98777.1 - 0.061 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 KFO98777.1 - 0.079 11.8 0.2 0.16 10.7 0.1 1.5 1 0 0 1 1 1 0 Peptidase M66 GDNF PF02351.11 KFO98779.1 - 1.8e-43 146.9 42.4 2.3e-20 72.8 5.0 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain Kelch_1 PF01344.20 KFO98780.1 - 1e-24 85.7 2.4 1.2e-06 27.9 0.0 6.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFO98780.1 - 6.9e-23 79.8 12.0 2.2e-07 30.7 0.0 6.8 7 0 0 7 7 6 5 Kelch motif Kelch_4 PF13418.1 KFO98780.1 - 8.4e-23 79.8 6.5 0.00039 20.1 0.0 6.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO98780.1 - 1.4e-19 69.6 14.3 1.2e-06 28.3 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 KFO98780.1 - 2.5e-19 68.8 2.4 5.1e-05 23.3 0.0 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Lectin_C PF00059.16 KFO98780.1 - 1.5e-18 67.3 0.5 1.5e-18 67.3 0.4 3.7 3 0 0 3 3 2 1 Lectin C-type domain PSI PF01437.20 KFO98780.1 - 2.9e-16 59.3 109.2 6.7e-11 42.1 6.3 7.8 8 0 0 8 8 7 5 Plexin repeat Kelch_2 PF07646.10 KFO98780.1 - 1.4e-13 49.9 3.0 0.03 14.0 0.0 6.4 6 0 0 6 6 6 4 Kelch motif CUB PF00431.15 KFO98780.1 - 8.8e-13 48.2 0.0 3.4e-12 46.4 0.0 2.1 1 0 0 1 1 1 1 CUB domain Laminin_EGF PF00053.19 KFO98780.1 - 0.0015 18.3 16.6 0.0015 18.3 11.5 7.8 8 2 1 9 9 5 2 Laminin EGF-like (Domains III and V) Rax2 PF12768.2 KFO98780.1 - 0.0057 15.9 0.3 2.2 7.4 0.1 2.3 1 1 0 2 2 2 2 Cortical protein marker for cell polarity HCO3_cotransp PF00955.16 KFO98782.1 - 3e-98 329.7 9.9 4e-98 329.2 6.8 1.1 1 0 0 1 1 1 1 HCO3- transporter family PTS_EIIA_2 PF00359.17 KFO98782.1 - 1.6e-07 31.1 0.0 2.2e-06 27.4 0.0 2.6 2 1 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Band_3_cyto PF07565.8 KFO98782.1 - 4.7e-06 26.3 0.0 1.4e-05 24.7 0.0 1.6 1 1 0 2 2 2 1 Band 3 cytoplasmic domain 7tm_1 PF00001.16 KFO98783.1 - 2.4e-78 262.8 11.4 3.2e-78 262.4 7.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO98783.1 - 5.9e-09 35.4 10.8 1.2e-08 34.4 7.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFO98783.1 - 0.0029 16.7 6.3 0.0029 16.7 4.4 1.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Haemadin PF09065.5 KFO98783.1 - 0.16 11.5 0.4 0.42 10.2 0.1 1.8 2 0 0 2 2 2 0 Haemadin NADH-u_ox-rdase PF10785.4 KFO98783.1 - 1 9.6 4.0 1.1 9.5 0.1 2.9 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DDRGK PF09756.4 KFO98784.1 - 2.9e-67 225.7 31.2 2.9e-67 225.7 21.6 1.5 2 0 0 2 2 2 1 DDRGK domain PCI PF01399.22 KFO98784.1 - 0.0001 22.5 0.1 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 PCI domain FeoC PF09012.5 KFO98784.1 - 0.00017 21.2 0.1 0.47 10.1 0.0 2.6 2 0 0 2 2 2 2 FeoC like transcriptional regulator UPF0181 PF03701.9 KFO98784.1 - 0.0049 16.1 0.0 0.023 13.9 0.0 2.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) HTH_DeoR PF08220.7 KFO98784.1 - 0.0065 15.9 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 2 DeoR-like helix-turn-helix domain MIP-T3 PF10243.4 KFO98784.1 - 2.9 6.2 33.3 4.7 5.5 23.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pox_G5 PF04599.7 KFO98784.1 - 3 6.4 9.2 4.1 5.9 6.4 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein GAGA_bind PF06217.7 KFO98784.1 - 9.3 6.1 11.1 13 5.6 7.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Fez1 PF06818.10 KFO98786.1 - 4.2e-75 252.2 23.9 4.2e-75 252.2 16.5 2.3 2 0 0 2 2 2 1 Fez1 MAD PF05557.8 KFO98786.1 - 1.8 6.5 49.9 0.0085 14.2 19.2 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein GAS PF13851.1 KFO98786.1 - 2.9 7.0 60.3 0.53 9.4 18.8 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding U-box PF04564.10 KFO98787.1 - 2.5e-26 91.4 0.1 5.4e-26 90.3 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.1 KFO98787.1 - 4e-05 23.2 5.6 4e-05 23.2 3.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFO98787.1 - 0.00059 19.5 4.4 0.0043 16.7 0.2 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFO98787.1 - 0.00064 19.6 6.6 0.00064 19.6 4.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO98787.1 - 0.0013 18.5 5.7 0.0013 18.5 3.9 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO98787.1 - 0.0041 16.7 4.5 0.0041 16.7 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO98787.1 - 0.0059 16.2 4.4 0.0059 16.2 3.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFO98787.1 - 0.11 12.3 5.2 0.39 10.6 3.6 2.0 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 KFO98787.1 - 0.18 11.7 11.6 0.047 13.5 4.9 2.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Hormone_5 PF00184.12 KFO98788.1 - 3.1e-30 104.5 24.2 3.5e-30 104.3 16.8 1.0 1 0 0 1 1 1 1 Neurohypophysial hormones, C-terminal Domain MRP-S26 PF14943.1 KFO98789.1 - 9.3e-34 116.4 15.9 1e-33 116.2 11.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 Tom37_C PF11801.3 KFO98789.1 - 0.22 11.3 5.2 0.26 11.1 3.6 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain APG6 PF04111.7 KFO98789.1 - 2.6 7.0 13.5 3 6.8 9.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3451 PF11933.3 KFO98789.1 - 2.8 7.6 10.2 3.4 7.3 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) DUF3987 PF13148.1 KFO98789.1 - 6.1 5.3 8.2 6 5.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) I-set PF07679.11 KFO98790.1 - 1.2e-35 121.2 0.8 6.1e-14 51.6 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO98790.1 - 1e-29 102.4 0.4 7.1e-13 48.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFO98790.1 - 9.8e-25 86.8 2.9 4e-11 43.2 0.1 3.5 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.20 KFO98790.1 - 2.3e-22 78.8 3.9 6.5e-12 45.4 0.0 4.2 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFO98790.1 - 1.2e-16 60.6 2.4 0.00016 21.5 0.1 4.8 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO98790.1 - 3.5e-06 26.8 0.1 0.11 12.3 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 KFO98790.1 - 0.0026 17.5 0.1 1.1 9.0 0.0 3.0 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.11 KFO98790.1 - 0.0034 15.7 0.1 0.22 9.7 0.0 2.8 2 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E C2-set PF05790.10 KFO98790.1 - 0.052 13.5 0.1 73 3.4 0.0 4.1 4 1 0 4 4 4 0 Immunoglobulin C2-set domain Phage_XkdX PF09693.5 KFO98790.1 - 0.15 11.6 0.3 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) I-set PF07679.11 KFO98791.1 - 8.2e-37 124.9 2.8 3.2e-15 55.7 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO98791.1 - 6.2e-28 96.7 2.1 2.8e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFO98791.1 - 1.4e-23 83.1 5.6 1.7e-10 41.2 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFO98791.1 - 2e-20 72.6 2.7 4.5e-10 39.4 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFO98791.1 - 1.3e-14 54.0 7.7 0.00015 21.5 0.1 4.7 3 2 0 3 3 3 3 Immunoglobulin V-set domain V-set_CD47 PF08204.6 KFO98791.1 - 0.001 18.7 2.1 0.32 10.7 0.1 3.1 3 1 0 3 3 3 2 CD47 immunoglobulin-like domain C2-set_2 PF08205.7 KFO98791.1 - 0.0016 18.3 0.1 0.53 10.2 0.0 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFO98791.1 - 0.01 14.1 0.5 0.056 11.7 0.2 2.2 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E I-set PF07679.11 KFO98792.1 - 2.7e-54 180.9 0.0 1.4e-15 56.9 0.0 5.6 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO98792.1 - 1.1e-41 140.8 0.0 3.8e-11 42.9 0.0 5.3 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFO98792.1 - 6.9e-33 112.9 2.3 6.9e-10 39.2 0.0 6.6 6 1 0 6 6 6 5 Immunoglobulin domain ig PF00047.20 KFO98792.1 - 6.8e-28 96.5 0.0 7e-10 38.8 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFO98792.1 - 1.6e-24 86.0 0.0 1.6e-07 31.1 0.0 6.3 5 1 0 5 5 5 3 Immunoglobulin V-set domain fn3 PF00041.16 KFO98792.1 - 1.8e-14 53.5 0.0 1e-05 25.5 0.0 3.2 3 0 0 3 3 3 2 Fibronectin type III domain C2-set_2 PF08205.7 KFO98792.1 - 0.00018 21.3 1.8 0.081 12.8 0.0 4.4 5 0 0 5 5 5 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFO98792.1 - 0.0034 15.7 0.0 14 3.7 0.0 4.0 3 2 0 4 4 4 0 Alphaherpesvirus glycoprotein E Tissue_fac PF01108.12 KFO98792.1 - 0.0061 16.2 0.1 0.12 12.0 0.1 2.5 2 0 0 2 2 2 1 Tissue factor Ldr_toxin PF13940.1 KFO98792.1 - 0.052 13.3 0.7 6.1 6.7 0.3 3.0 1 1 1 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system SLAM PF06214.6 KFO98792.1 - 0.089 12.7 0.1 5 7.0 0.0 2.6 3 0 0 3 3 3 0 Signaling lymphocytic activation molecule (SLAM) protein V-set_CD47 PF08204.6 KFO98792.1 - 0.12 12.1 0.0 29 4.4 0.0 3.7 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain I-set PF07679.11 KFO98793.1 - 2e-20 72.4 0.1 1.5e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFO98793.1 - 1.2e-17 63.8 1.5 1.3e-08 34.7 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFO98793.1 - 2.1e-16 59.7 1.2 6.9e-09 35.7 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFO98793.1 - 1.9e-12 47.0 4.3 2.1e-05 24.5 0.4 3.4 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFO98793.1 - 1.7e-09 38.0 6.8 1.2e-06 28.8 1.3 3.1 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFO98793.1 - 2e-05 24.3 0.6 0.0044 16.8 0.1 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFO98793.1 - 5e-05 23.2 0.2 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin C1-set domain Adeno_E3_CR2 PF02439.10 KFO98793.1 - 0.051 13.1 3.4 0.099 12.2 2.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 KFO98793.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cnd1 PF12717.2 KFO98794.1 - 1.8e-63 213.6 22.4 6.3e-57 192.2 3.6 6.5 4 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KFO98794.1 - 1.2e-10 40.5 11.8 1.5 9.0 0.0 9.0 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 KFO98794.1 - 1.1e-06 28.8 2.9 0.29 11.4 0.0 5.9 5 2 1 6 6 6 3 HEAT repeats Cohesin_HEAT PF12765.2 KFO98794.1 - 2.8e-06 27.1 0.7 0.0061 16.4 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 KFO98794.1 - 0.002 17.9 1.0 2.7 7.9 0.1 4.8 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) DUF3013 PF11217.3 KFO98794.1 - 0.0033 17.1 0.5 0.0069 16.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3013) OSCP PF00213.13 KFO98794.1 - 0.036 13.9 2.0 0.23 11.3 1.0 2.5 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit Vps26 PF03643.10 KFO98795.1 - 1.4e-130 434.0 6.5 1.6e-130 433.8 4.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFO98795.1 - 6.8e-05 22.7 2.0 0.022 14.5 0.1 3.7 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain EVE PF01878.13 KFO98796.1 - 1.1e-51 174.6 0.1 1.8e-51 173.8 0.1 1.3 1 0 0 1 1 1 1 EVE domain Acyl-CoA_dh_1 PF00441.19 KFO98797.1 - 1.8e-46 157.9 5.0 2.2e-46 157.6 3.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFO98797.1 - 1.3e-27 96.6 0.3 3.2e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFO98797.1 - 2.3e-22 79.6 2.1 3.7e-22 79.0 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFO98797.1 - 3.3e-20 71.3 0.1 8.2e-20 70.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glyco_transf_43 PF03360.11 KFO98798.1 - 3.4e-82 275.0 0.0 3.9e-82 274.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 MRP-S32 PF10210.4 KFO98799.1 - 4e-40 136.0 1.1 4.8e-40 135.7 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 SH2 PF00017.19 KFO98800.1 - 1.8e-13 50.1 0.1 2.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 KFO98800.1 - 1.9e-13 50.0 0.2 3.6e-13 49.1 0.2 1.5 1 0 0 1 1 1 1 SOCS box CARD PF00619.16 KFO98801.1 - 1.4e-16 60.0 0.1 2.4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Death PF00531.17 KFO98801.1 - 9.3e-14 50.9 0.4 1.4e-11 43.9 0.1 2.4 2 0 0 2 2 2 2 Death domain GAS PF13851.1 KFO98803.1 - 0.004 16.3 22.6 0.004 16.3 15.7 6.7 2 1 5 7 7 7 6 Growth-arrest specific micro-tubule binding Tmemb_cc2 PF10267.4 KFO98804.1 - 7.1e-171 568.1 15.0 8.1e-171 567.9 10.4 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Rootletin PF15035.1 KFO98804.1 - 0.0017 18.3 1.7 0.0017 18.3 1.2 3.7 2 1 1 3 3 3 1 Ciliary rootlet component, centrosome cohesion DUF2407_C PF13373.1 KFO98804.1 - 0.021 14.7 0.2 0.021 14.7 0.1 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain Orbi_NS3 PF01616.11 KFO98804.1 - 0.035 13.0 2.7 0.089 11.7 1.8 1.6 1 0 0 1 1 1 0 Orbivirus NS3 TMCO5 PF14992.1 KFO98804.1 - 0.26 10.3 21.5 0.66 9.0 5.2 2.3 2 0 0 2 2 2 0 TMCO5 family CorA PF01544.13 KFO98804.1 - 0.58 9.1 13.0 1.1 8.1 0.5 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4618 PF15397.1 KFO98804.1 - 0.68 9.2 21.6 0.12 11.6 4.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) COG2 PF06148.6 KFO98804.1 - 0.72 9.7 18.9 0.2 11.5 4.2 3.3 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Effector_1 PF04518.7 KFO98804.1 - 1.1 8.1 17.1 0.14 11.1 3.8 2.3 2 0 0 2 2 2 0 Effector from type III secretion system Phage_GPO PF05929.6 KFO98804.1 - 5.8 6.0 21.6 0.086 12.0 2.2 2.9 3 1 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Lipoprotein_20 PF13942.1 KFO98804.1 - 5.9 6.3 20.3 2.1 7.8 4.7 2.4 2 0 0 2 2 2 0 YfhG lipoprotein Baculo_PEP_C PF04513.7 KFO98804.1 - 8.7 6.1 11.7 4.3 7.1 2.7 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus G10 PF01125.12 KFO98804.1 - 9.3 5.7 10.8 0.38 10.3 2.1 2.3 2 1 0 2 2 2 0 G10 protein NDUFA12 PF05071.11 KFO98805.1 - 9.3e-31 106.4 3.4 1.2e-30 106.0 2.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hormone_recep PF00104.25 KFO98806.1 - 4.7e-33 114.0 0.6 8.8e-33 113.1 0.4 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO98806.1 - 1.7e-31 108.2 15.5 3.8e-31 107.1 10.8 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF2318 PF10080.4 KFO98806.1 - 0.013 15.2 0.7 0.013 15.2 0.5 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) RhoGEF PF00621.15 KFO98807.1 - 1.7e-39 135.5 2.1 1.7e-39 135.5 1.5 2.4 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 KFO98807.1 - 3.2e-20 71.7 10.2 3.2e-20 71.7 7.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 KFO98807.1 - 3.5e-17 62.4 1.2 5.6e-09 36.1 0.0 3.0 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFO98807.1 - 6.7e-07 29.5 1.1 0.052 13.7 0.0 3.2 3 0 0 3 3 3 2 Pleckstrin homology domain FYVE_2 PF02318.11 KFO98807.1 - 0.00097 19.0 10.5 0.0039 17.0 7.3 2.0 1 0 0 1 1 1 1 FYVE-type zinc finger Vezatin PF12632.2 KFO98808.1 - 1.6e-56 191.2 0.6 3.3e-56 190.1 0.4 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Peptidase_M24 PF00557.19 KFO98810.1 - 1.8e-49 168.1 0.0 2.3e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 UCH PF00443.24 KFO98811.1 - 9.1e-62 208.6 1.2 9.1e-62 208.6 0.8 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFO98811.1 - 2.8e-20 72.2 8.0 2.8e-20 72.2 5.5 3.4 4 1 1 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFO98811.1 - 7.9e-18 64.9 3.8 4.3e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Laminin_N PF00055.12 KFO98813.1 - 1.6e-33 115.6 0.0 3e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFO98813.1 - 4.9e-31 106.4 53.2 5.6e-12 45.4 4.1 5.4 4 1 1 5 5 5 4 Laminin EGF-like (Domains III and V) NTR PF01759.16 KFO98813.1 - 2.1e-22 78.7 0.3 6.3e-22 77.2 0.2 1.9 1 0 0 1 1 1 1 UNC-6/NTR/C345C module F5_F8_type_C PF00754.20 KFO98813.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain LSM PF01423.17 KFO98814.1 - 2.5e-15 55.7 0.0 2.7e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFO98814.1 - 0.037 13.9 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF669 PF05037.8 KFO98814.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Amidohydro_4 PF13147.1 KFO98815.1 - 3e-22 79.9 2.1 4.3e-21 76.1 1.5 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFO98815.1 - 3.5e-14 53.1 1.0 3.2e-09 36.8 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KFO98815.1 - 2.1e-12 47.0 4.5 6.1e-10 38.8 0.1 2.6 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFO98815.1 - 9.6e-11 41.3 0.1 2.8e-10 39.8 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Lyase_aromatic PF00221.14 KFO98816.1 - 2e-188 626.6 0.0 2.4e-188 626.4 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase DUF3534 PF12053.3 KFO98816.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) Peptidase_M1 PF01433.15 KFO98817.1 - 2e-66 224.7 0.0 2.5e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFO98817.1 - 1.5e-45 154.3 0.3 2.5e-45 153.5 0.2 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFO98817.1 - 1.4e-16 60.7 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KFO98817.1 - 0.25 11.3 1.8 1.2 9.0 1.2 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase FH2 PF02181.18 KFO98818.1 - 1.3e-78 264.5 14.6 2.1e-78 263.7 10.1 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 KFO98818.1 - 1.9e-31 108.9 4.7 1.9e-31 108.9 3.2 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 KFO98818.1 - 3.1e-17 62.5 0.4 3.1e-17 62.5 0.3 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH1 PF06346.7 KFO98818.1 - 3.5e-06 26.6 62.1 3.5e-06 26.6 43.1 2.6 1 1 1 2 2 2 2 Formin Homology Region 1 WH2 PF02205.15 KFO98818.1 - 0.00056 19.4 0.1 0.0017 17.8 0.1 1.9 1 0 0 1 1 1 1 WH2 motif DUF1212 PF06738.7 KFO98818.1 - 0.099 12.0 0.6 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Adenylsucc_synt PF00709.16 KFO98819.1 - 1.3e-148 495.1 0.0 1.5e-148 494.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Siva PF05458.7 KFO98820.1 - 2.5e-16 59.7 21.0 2.6e-16 59.6 14.6 1.0 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Pkinase PF00069.20 KFO98821.1 - 1.2e-75 254.0 0.0 1.7e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98821.1 - 6.5e-36 123.7 0.0 9.9e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KFO98821.1 - 1.1e-08 35.1 0.3 3.6e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 KFO98821.1 - 3.9e-08 32.6 0.0 1.7e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 KFO98821.1 - 2.4e-07 31.1 3.0 6.2e-07 29.8 2.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.1 KFO98821.1 - 0.032 14.4 0.7 0.24 11.6 0.5 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Seadorna_VP7 PF07387.6 KFO98821.1 - 0.036 12.8 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KFO98821.1 - 0.071 12.8 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family BTB PF00651.26 KFO98822.1 - 2.8e-26 91.6 0.6 4.7e-26 90.9 0.4 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFO98822.1 - 2.3e-13 49.7 27.3 4.2e-08 33.0 1.0 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFO98822.1 - 2.1e-12 46.6 32.5 0.0012 19.0 1.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO98822.1 - 2.1e-11 43.3 29.8 0.006 16.8 2.0 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO98822.1 - 0.00016 21.7 13.9 0.07 13.2 0.0 4.7 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO98822.1 - 0.00077 19.5 14.0 0.07 13.3 0.1 4.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFO98822.1 - 0.018 14.9 1.0 0.018 14.9 0.7 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger GAGA PF09237.6 KFO98822.1 - 0.075 12.6 6.6 0.44 10.1 0.1 3.3 2 1 1 3 3 3 0 GAGA factor PLDc_3 PF13918.1 KFO98823.1 - 3.6e-38 130.7 0.0 6.2e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc_2 PF13091.1 KFO98823.1 - 4.5e-24 84.5 0.7 9e-13 48.0 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFO98823.1 - 1e-13 50.5 4.2 1.8e-08 33.9 0.4 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif DOR PF14839.1 KFO98824.1 - 2.6e-50 171.1 3.2 1.2e-49 168.9 2.2 1.8 1 1 0 1 1 1 1 DOR family G_glu_transpept PF01019.16 KFO98825.1 - 7e-125 417.4 0.0 8.1e-125 417.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3000 PF11452.3 KFO98825.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Rab5ip PF07019.7 KFO98826.1 - 3.3e-28 97.6 9.1 3.8e-28 97.4 6.3 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Clc-like PF07062.7 KFO98826.1 - 0.07 12.3 3.5 0.083 12.1 2.4 1.0 1 0 0 1 1 1 0 Clc-like DUF441 PF04284.8 KFO98826.1 - 0.099 12.5 1.9 0.16 11.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF441) DUF2244 PF10003.4 KFO98826.1 - 0.28 10.5 4.5 0.21 10.9 0.5 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Yip1 PF04893.12 KFO98826.1 - 0.57 9.6 10.3 3.8 6.9 6.5 1.9 1 1 1 2 2 2 0 Yip1 domain EF-hand_1 PF00036.27 KFO98827.1 - 1.7e-16 58.1 9.7 5.2e-08 31.6 1.1 4.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 KFO98827.1 - 4.5e-13 49.1 6.8 1.3e-08 34.8 0.6 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFO98827.1 - 1.1e-12 46.6 7.4 6.6e-08 31.8 0.6 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFO98827.1 - 1.3e-10 40.7 8.5 1.4e-05 24.6 0.1 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFO98827.1 - 4.8e-06 25.6 3.0 1.4e-05 24.1 0.9 2.5 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.8 KFO98827.1 - 0.00037 20.0 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 KFO98827.1 - 0.0046 16.8 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFO98827.1 - 0.066 13.2 0.5 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1880 PF08976.6 KFO98827.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) Homeobox_KN PF05920.6 KFO98828.1 - 0.0018 17.9 2.7 0.0029 17.2 1.9 1.3 1 0 0 1 1 1 1 Homeobox KN domain AdoHcyase PF05221.12 KFO98829.1 - 1.3e-144 480.0 0.1 1.6e-144 479.7 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KFO98829.1 - 3.8e-87 290.2 3.5 6.1e-87 289.5 2.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFO98829.1 - 6.1e-10 38.5 0.1 1.1e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KFO98829.1 - 9.6e-06 25.0 0.2 1.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KFO98829.1 - 0.0014 18.5 0.1 0.0033 17.4 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KFO98829.1 - 0.033 13.7 0.1 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 KFO98829.1 - 0.036 14.1 0.2 0.067 13.3 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KFO98829.1 - 0.068 12.8 0.8 0.21 11.1 0.6 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Agouti PF05039.7 KFO98830.1 - 1.3e-17 63.9 11.8 1.8e-17 63.4 8.2 1.2 1 0 0 1 1 1 1 Agouti protein STIL_N PF15253.1 KFO98830.1 - 0.037 12.7 0.4 0.041 12.6 0.3 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Toxin_9 PF02819.10 KFO98830.1 - 4.4 7.4 18.2 3.4 7.8 11.4 1.7 2 0 0 2 2 2 0 Spider toxin Yae1_N PF09811.4 KFO98831.1 - 7.2e-17 60.6 46.5 1.5e+04 -8.2 32.2 4.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Trypsin PF00089.21 KFO98832.1 - 1.9e-20 73.3 0.1 2e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFO98832.1 - 0.051 12.8 0.9 1.2 8.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1986) Ras PF00071.17 KFO98833.1 - 5e-32 110.5 0.0 6.1e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98833.1 - 2.7e-14 53.6 0.0 4.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO98833.1 - 4.1e-08 32.6 0.0 6.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO98833.1 - 1.1e-06 28.2 0.1 2e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFO98833.1 - 4e-06 26.1 0.1 7.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFO98833.1 - 0.016 14.7 0.1 0.023 14.2 0.1 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein NDK PF00334.14 KFO98834.1 - 2.7e-17 62.8 0.0 3.2e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ank PF00023.25 KFO98836.1 - 4.1e-30 102.0 9.0 3.1e-10 39.3 0.4 4.5 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KFO98836.1 - 1.6e-28 98.8 3.4 2.7e-15 56.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO98836.1 - 2.2e-26 91.7 3.3 1.8e-12 47.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO98836.1 - 4.5e-25 87.1 8.5 2.8e-10 40.0 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO98836.1 - 1.9e-18 64.6 3.4 4.2e-07 29.5 0.1 4.0 4 1 0 4 4 4 3 Ankyrin repeat rve PF00665.21 KFO98837.1 - 1.3e-28 99.4 0.1 2.3e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 KFO98837.1 - 1.8e-11 43.2 0.4 4.5e-11 42.0 0.3 1.7 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.19 KFO98837.1 - 4.9e-10 39.8 0.0 8.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RNase H DDE_Tnp_IS240 PF13610.1 KFO98837.1 - 0.00035 20.5 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.1 KFO98837.1 - 0.0043 16.5 0.1 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain GDE_C PF06202.9 KFO98837.1 - 0.071 11.8 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Keratin PF02422.11 KFO98839.1 - 2.5e-31 107.5 6.1 2.7e-31 107.4 4.2 1.0 1 0 0 1 1 1 1 Keratin IncA PF04156.9 KFO98840.1 - 0.11 12.0 93.6 0.44 10.1 23.6 3.1 2 1 1 3 3 3 0 IncA protein Tropomyosin_1 PF12718.2 KFO98840.1 - 5 6.9 85.3 0.14 12.0 6.9 3.9 1 1 1 3 3 3 0 Tropomyosin like Beta-lactamase PF00144.19 KFO98841.1 - 4.9e-37 127.6 0.0 7.1e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Pkinase_Tyr PF07714.12 KFO98842.1 - 4.1e-98 327.5 0.0 4.7e-98 327.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO98842.1 - 2.7e-49 167.6 0.0 3.2e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFO98842.1 - 3.6e-14 52.8 1.2 6.4e-14 52.1 0.8 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.9 KFO98842.1 - 0.075 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Collagen PF01391.13 KFO98844.1 - 9.1e-18 63.5 54.0 2e-10 40.0 18.5 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) C1q PF00386.16 KFO98844.1 - 6.8e-14 51.9 0.0 8.1e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 C1q domain C1q PF00386.16 KFO98845.1 - 7.4e-33 113.2 0.0 8.9e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFO98845.1 - 3.8e-12 45.5 36.9 6.9e-08 31.9 15.1 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNF PF00229.13 KFO98845.1 - 0.1 12.1 0.3 1.9 8.0 0.2 2.1 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Pkinase_Tyr PF07714.12 KFO98846.1 - 3.5e-91 304.8 0.0 4.9e-91 304.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFO98846.1 - 8.6e-73 243.9 0.0 1.3e-72 243.2 0.0 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFO98846.1 - 3.2e-45 154.3 0.0 4.7e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFO98846.1 - 2.8e-33 113.8 0.0 1.2e-16 60.6 0.1 2.9 3 0 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.1 KFO98846.1 - 1.1e-22 80.1 0.0 2.1e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 KFO98846.1 - 1.2e-20 73.3 0.1 2.2e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFO98846.1 - 2.2e-16 59.4 0.1 4.9e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SusE PF14292.1 KFO98846.1 - 0.00018 21.3 0.0 0.17 11.6 0.2 2.4 2 0 0 2 2 2 2 SusE outer membrane protein GCC2_GCC3 PF07699.8 KFO98846.1 - 0.0017 17.8 4.9 0.0017 17.8 3.4 2.3 2 0 0 2 2 2 1 GCC2 and GCC3 Interfer-bind PF09294.5 KFO98846.1 - 0.0025 17.8 0.0 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Kdo PF06293.9 KFO98846.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3300 PF11737.3 KFO98846.1 - 0.31 10.2 4.1 3.2 6.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3300) wnt PF00110.14 KFO98848.1 - 1.9e-127 424.7 25.0 2.1e-127 424.6 17.4 1.0 1 0 0 1 1 1 1 wnt family Ras PF00071.17 KFO98849.1 - 3.7e-50 169.4 0.0 4.1e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO98849.1 - 5.6e-16 59.1 0.0 1.2e-15 58.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFO98849.1 - 1.8e-06 27.3 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFO98849.1 - 0.03 14.2 0.0 0.22 11.4 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ORC3_N PF07034.6 KFO98849.1 - 0.11 11.3 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF2452 PF10504.4 KFO98850.1 - 8.9e-60 200.6 0.3 1e-59 200.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) PMP22_Claudin PF00822.15 KFO98851.1 - 4.6e-25 88.2 3.8 5.8e-25 87.8 2.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO98851.1 - 7.7e-09 35.4 6.5 1e-08 35.0 4.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 KFO98851.1 - 0.02 15.0 2.7 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Amastin PF07344.6 KFO98851.1 - 0.052 13.1 4.7 0.025 14.1 2.0 1.4 1 1 1 2 2 2 0 Amastin surface glycoprotein H_PPase PF03030.11 KFO98851.1 - 0.07 11.3 0.7 0.076 11.2 0.5 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF204 PF02659.10 KFO98851.1 - 0.083 13.0 3.7 0.1 12.7 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF DUF3429 PF11911.3 KFO98851.1 - 0.17 11.8 2.3 0.15 12.0 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3429) DUF4131 PF13567.1 KFO98851.1 - 0.2 11.0 1.5 0.38 10.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1218 PF06749.7 KFO98851.1 - 0.3 11.5 3.2 2.3 8.7 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) CD20 PF04103.10 KFO98851.1 - 8.8 6.2 11.1 16 5.4 1.3 2.4 1 1 1 2 2 2 0 CD20-like family PMP22_Claudin PF00822.15 KFO98852.1 - 9.6e-17 61.1 7.0 1.2e-16 60.8 4.8 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO98852.1 - 1.2e-11 44.6 4.0 2.1e-11 43.8 2.8 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KFO98852.1 - 0.0086 16.0 4.7 0.014 15.3 3.2 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PIRT PF15099.1 KFO98852.1 - 0.054 12.7 0.1 0.13 11.4 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family CSD PF00313.17 KFO98853.1 - 7.3e-28 96.1 0.6 1.3e-27 95.3 0.4 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KFO98853.1 - 0.0048 16.3 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain DNA_pol_A_exo1 PF01612.15 KFO98854.1 - 3.5e-48 163.4 1.1 3.5e-48 163.4 0.8 1.6 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 KFO98854.1 - 9.3e-26 89.9 0.0 2.1e-24 85.6 0.0 2.6 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 KFO98854.1 - 1.7e-14 53.2 0.6 3.1e-13 49.2 0.0 2.5 2 0 0 2 2 2 1 HRDC domain AATF-Che1 PF13339.1 KFO98854.1 - 2.1 8.5 17.7 87 3.2 8.5 3.9 3 1 1 4 4 4 0 Apoptosis antagonizing transcription factor DUF3359 PF11839.3 KFO98854.1 - 7.5 6.9 10.5 9 6.7 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) UbiA PF01040.13 KFO98855.1 - 3.8e-38 131.1 15.4 4.9e-38 130.8 10.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Tom22 PF04281.8 KFO98855.1 - 0.17 11.3 0.4 2.2 7.8 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Patched PF02460.13 KFO98857.1 - 5.1e-24 84.2 24.0 9.6e-20 70.1 1.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KFO98857.1 - 6.6e-14 51.6 12.0 6.6e-14 51.6 8.3 3.4 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KFO98857.1 - 1.5e-13 50.2 30.6 2e-09 36.6 4.1 2.3 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.14 KFO98857.1 - 0.0024 15.3 5.8 0.0046 14.4 4.0 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Repressor_Mnt PF11423.3 KFO98857.1 - 0.16 11.3 0.2 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 Regulatory protein Mnt FBA PF04300.8 KFO98858.1 - 2.5e-84 281.8 1.2 2.9e-84 281.5 0.8 1.1 1 0 0 1 1 1 1 F-box associated region F-box PF00646.28 KFO98858.1 - 8.1e-10 38.1 0.8 1.4e-09 37.3 0.5 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFO98858.1 - 5.1e-07 29.3 1.6 1.3e-06 28.0 1.1 1.7 1 0 0 1 1 1 1 F-box-like FBA PF04300.8 KFO98859.1 - 2.5e-79 265.5 0.3 3e-79 265.2 0.2 1.1 1 0 0 1 1 1 1 F-box associated region F-box-like PF12937.2 KFO98859.1 - 3.4e-12 45.9 2.8 8.2e-12 44.6 2.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFO98859.1 - 1.5e-07 30.8 1.9 2.8e-07 30.0 1.3 1.5 1 0 0 1 1 1 1 F-box domain HORMA PF02301.13 KFO98860.1 - 4.3e-25 88.4 0.1 5.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 HORMA domain Draxin PF15550.1 KFO98861.1 - 3.9e-141 470.4 10.0 4.3e-141 470.2 6.9 1.0 1 0 0 1 1 1 1 Draxin AGTRAP PF06396.6 KFO98862.1 - 4.5e-53 179.2 2.2 5e-53 179.1 1.5 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) FxsA PF04186.8 KFO98862.1 - 0.099 12.2 0.3 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein MTHFR PF02219.12 KFO98863.1 - 5e-119 396.6 0.0 6.5e-119 396.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Voltage_CLC PF00654.15 KFO98864.1 - 7.3e-95 317.9 25.4 7.6e-95 317.9 12.4 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 KFO98864.1 - 4.6e-15 55.1 0.2 3.2e-09 36.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain ANP PF00212.13 KFO98865.1 - 1.5e-13 50.5 9.7 2.4e-13 49.9 6.7 1.3 1 0 0 1 1 1 1 Atrial natriuretic peptide Guanylate_cyc PF00211.15 KFO98866.1 - 6.7e-68 227.6 0.0 8e-68 227.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFO98866.1 - 0.00058 19.1 1.1 0.001 18.2 0.7 1.4 1 0 0 1 1 1 1 Heme NO binding associated Trypsin PF00089.21 KFO98867.1 - 3.9e-68 229.3 0.6 4.4e-68 229.1 0.4 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFO98867.1 - 0.00057 19.2 0.1 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFO98867.1 - 0.0015 18.5 0.0 0.004 17.1 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF2152 PF10222.4 KFO98868.1 - 1.2e-174 581.8 0.7 1.4e-174 581.7 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) 2OG-FeII_Oxy PF03171.15 KFO98869.1 - 4.8e-09 36.4 0.0 9.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.9 KFO98869.1 - 4.7e-06 25.9 0.1 0.074 12.1 0.0 2.4 2 0 0 2 2 2 2 Anp1 Fzo_mitofusin PF04799.8 KFO98870.1 - 2.9e-83 277.4 6.3 4.3e-83 276.8 0.5 2.7 3 0 0 3 3 3 1 fzo-like conserved region Dynamin_N PF00350.18 KFO98870.1 - 2.9e-24 85.7 0.5 1.6e-23 83.3 0.0 2.5 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KFO98870.1 - 1.1e-06 28.6 0.0 5.3e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Apolipoprotein PF01442.13 KFO98870.1 - 0.0039 16.7 7.7 0.028 13.9 1.8 2.6 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain AAA_29 PF13555.1 KFO98870.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KFO98870.1 - 7.3 6.8 7.9 43 4.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain TNFR_c6 PF00020.13 KFO98872.1 - 9.1e-08 32.0 43.6 0.0015 18.5 3.9 4.6 4 0 0 4 4 4 4 TNFR/NGFR cysteine-rich region Yae1_N PF09811.4 KFO98873.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ricin_B_lectin PF00652.17 KFO98874.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Hus1 PF04005.7 KFO98875.1 - 0.00093 18.2 0.0 0.00095 18.2 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein adh_short PF00106.20 KFO98876.1 - 3.5e-26 92.0 0.2 2.6e-25 89.2 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFO98876.1 - 4.1e-13 49.3 0.2 1.4e-12 47.6 0.1 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFO98876.1 - 1.3e-08 34.9 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KFO98876.1 - 7.2e-07 28.3 0.0 1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KFO98876.1 - 0.00082 19.4 0.2 0.0016 18.5 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KFO98876.1 - 0.0063 15.9 0.1 0.0094 15.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 KFO98877.1 - 7.7e-55 185.7 0.0 4.1e-42 144.1 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 KFO98877.1 - 1.3e-06 27.4 0.2 8.8e-06 24.7 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFO98877.1 - 1.4e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFO98877.1 - 0.00033 19.4 0.0 0.00048 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF2920 PF11144.3 KFO98877.1 - 0.0055 15.7 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) Thioesterase PF00975.15 KFO98877.1 - 0.0091 16.2 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 KFO98877.1 - 0.019 14.2 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFO98878.1 - 1.1e-46 159.0 0.0 6.9e-34 117.2 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFO98878.1 - 0.0019 17.4 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KFO98878.1 - 0.0078 14.9 0.5 0.043 12.5 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFO98878.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.7 KFO98878.1 - 0.096 11.1 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) LRR_8 PF13855.1 KFO98880.1 - 4.5e-33 112.7 22.8 4.2e-13 48.8 2.2 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFO98880.1 - 1.9e-18 65.6 12.1 1.2e-07 31.1 0.4 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO98880.1 - 4.3e-14 50.3 14.7 0.023 14.6 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_5 PF13306.1 KFO98880.1 - 4.2e-09 36.1 1.3 1.2e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO98880.1 - 5.3e-06 25.7 13.3 0.34 11.2 0.2 6.2 6 0 0 6 6 6 2 Leucine rich repeat LRR_9 PF14580.1 KFO98880.1 - 0.011 15.3 2.1 0.18 11.3 0.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeat LRRNT PF01462.13 KFO98880.1 - 0.05 13.1 3.6 0.19 11.2 2.5 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFO98880.1 - 0.095 12.8 20.6 0.17 12.0 0.0 5.8 6 1 1 7 7 7 0 Leucine Rich repeat DUF3557 PF12078.3 KFO98880.1 - 0.11 12.2 0.1 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3557) LRR_3 PF07725.7 KFO98880.1 - 1.9 8.3 8.9 18 5.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat Podoplanin PF05808.6 KFO98881.1 - 2.1e-18 66.3 0.4 2.1e-16 59.9 0.3 2.0 1 1 0 1 1 1 1 Podoplanin VSP PF03302.8 KFO98881.1 - 0.043 12.4 0.4 0.05 12.2 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-C2H2_4 PF13894.1 KFO98882.1 - 2.1e-18 65.2 56.3 0.003 17.7 3.5 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO98882.1 - 3.1e-17 61.8 66.4 0.0065 16.7 1.3 8.7 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFO98882.1 - 2.9e-06 27.2 27.1 0.012 15.7 0.5 6.8 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFO98882.1 - 0.0014 18.7 62.2 0.022 15.0 0.6 10.4 11 0 0 11 11 11 5 Zinc-finger double domain PhnA_Zn_Ribbon PF08274.7 KFO98882.1 - 0.041 13.6 1.5 8.2 6.3 0.4 3.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon PyrI_C PF02748.10 KFO98882.1 - 1.1 8.7 19.5 2.5 7.6 0.1 5.9 6 1 1 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.4 KFO98882.1 - 4.4 7.2 13.2 7.8 6.4 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger domain zf-C2H2_6 PF13912.1 KFO98882.1 - 8.1 6.5 51.0 0.031 14.1 1.5 7.5 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFO98882.1 - 9.5 6.0 30.0 1.4 8.7 0.3 6.3 6 0 0 6 6 6 0 zinc-finger of a C2HC-type Cas6 PF09559.5 KFO98883.1 - 0.008 15.9 0.2 0.0098 15.6 0.2 1.0 1 0 0 1 1 1 1 Cas6 Crispr DUF148 PF02520.12 KFO98883.1 - 0.12 12.1 0.2 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF148 PF02520.12 KFO98884.1 - 0.0056 16.4 7.3 0.02 14.6 5.1 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF148 AAA_27 PF13514.1 KFO98884.1 - 0.032 11.9 26.3 0.043 11.5 18.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 KFO98884.1 - 0.034 12.6 18.6 0.047 12.1 12.9 1.2 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 KFO98884.1 - 1.1 8.3 3.2 2.1 7.4 1.9 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 KFO98884.1 - 1.9 8.0 34.4 1.1 8.7 0.1 4.7 3 1 2 5 5 5 0 Septum formation initiator DUF4279 PF14106.1 KFO98884.1 - 2 8.3 8.7 4.2 7.2 0.1 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4279) CENP-F_leu_zip PF10473.4 KFO98884.1 - 3.1 7.6 42.0 1 9.2 7.1 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PA26 PF04636.8 KFO98884.1 - 7.9 5.0 10.8 2.3 6.8 5.2 1.5 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) HALZ PF02183.13 KFO98884.1 - 9.8 5.9 20.3 3.6 7.3 1.0 4.0 3 1 0 3 3 3 0 Homeobox associated leucine zipper TMEM51 PF15345.1 KFO98885.1 - 1.6e-89 299.6 0.2 1.9e-89 299.4 0.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM61 PF15105.1 KFO98885.1 - 0.0062 16.0 3.0 0.062 12.8 0.3 3.0 2 1 1 3 3 3 1 TMEM61 protein family WBP-1 PF11669.3 KFO98885.1 - 0.034 14.2 0.1 0.59 10.2 0.0 2.6 3 0 0 3 3 3 0 WW domain-binding protein 1 RCR PF12273.3 KFO98885.1 - 0.042 14.3 0.2 0.078 13.5 0.2 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 KFO98885.1 - 0.069 11.4 0.0 0.089 11.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4131 PF13567.1 KFO98885.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PIRT PF15099.1 KFO98885.1 - 3.2 6.9 7.3 19 4.4 3.0 2.9 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family YqgF PF14639.1 KFO98886.1 - 0.0086 15.6 0.1 0.0098 15.4 0.1 1.3 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DUF342 PF03961.8 KFO98886.1 - 0.0092 14.4 1.7 0.01 14.3 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) VPS11_C PF12451.3 KFO98886.1 - 4 7.3 5.2 24 4.8 1.5 2.3 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal IncA PF04156.9 KFO98886.1 - 7.4 6.1 14.3 12 5.4 9.9 1.5 1 1 0 1 1 1 0 IncA protein EF-hand_7 PF13499.1 KFO98888.1 - 4.1e-08 33.2 0.6 9.5e-08 32.0 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFO98888.1 - 1.9e-07 29.8 7.2 0.0013 17.8 0.5 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFO98888.1 - 0.0004 20.0 2.1 0.041 13.7 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFO98888.1 - 0.00043 19.8 1.3 0.00083 18.9 0.9 1.5 1 0 0 1 1 1 1 EF-hand domain pair Decorin_bind PF02352.10 KFO98888.1 - 0.013 15.4 5.0 0.17 11.9 1.1 2.1 2 0 0 2 2 2 0 Decorin binding protein PcfJ PF14284.1 KFO98888.1 - 0.049 13.1 2.2 0.068 12.6 1.5 1.2 1 0 0 1 1 1 0 PcfJ-like protein EF-hand_5 PF13202.1 KFO98888.1 - 0.59 9.5 0.1 0.59 9.5 0.0 2.9 4 0 0 4 4 4 0 EF hand FAM165 PF14981.1 KFO98888.1 - 0.83 9.1 4.4 1.6 8.3 3.0 1.5 1 0 0 1 1 1 0 FAM165 family AAA_23 PF13476.1 KFO98888.1 - 0.9 9.8 7.2 1.1 9.5 5.0 1.1 1 0 0 1 1 1 0 AAA domain Trypsin PF00089.21 KFO98889.1 - 8.1e-69 231.5 0.5 9.2e-69 231.3 0.3 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFO98889.1 - 0.0089 16.0 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 KFO98889.1 - 0.011 15.0 0.2 0.02 14.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Peptidase_C14 PF00656.17 KFO98890.1 - 5.8e-39 134.2 0.0 7.5e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CARD PF00619.16 KFO98890.1 - 2.6e-14 52.8 0.1 4.6e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Caspase recruitment domain Pkinase PF00069.20 KFO98891.1 - 2.1e-27 95.9 0.0 4.7e-27 94.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98891.1 - 1.2e-14 54.0 0.0 3.6e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO98891.1 - 0.00054 19.0 0.0 0.0013 17.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFO98891.1 - 0.02 14.6 0.1 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFO98891.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL dCMP_cyt_deam_1 PF00383.17 KFO98892.1 - 2.4e-17 62.4 0.2 2.9e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KFO98892.1 - 1.4e-11 44.4 0.5 5.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.1 KFO98892.1 - 0.034 13.7 0.6 0.09 12.4 0.0 1.8 1 1 1 2 2 2 0 MafB19-like deaminase LmjF365940-deam PF14421.1 KFO98892.1 - 0.067 12.5 2.1 1.3 8.4 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PID_2 PF14719.1 KFO98893.1 - 2e-54 184.0 0.4 2.3e-54 183.7 0.3 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.18 KFO98893.1 - 2.9e-05 24.0 0.0 3.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) GIDE PF12483.3 KFO98894.1 - 1.3e-24 86.3 0.5 1.9e-24 85.8 0.0 1.4 2 0 0 2 2 2 1 E3 Ubiquitin ligase zf-C3HC4_3 PF13920.1 KFO98894.1 - 9.4e-13 47.6 14.0 1.4e-12 47.0 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO98894.1 - 0.00018 21.4 17.2 0.00031 20.7 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO98894.1 - 0.0019 17.8 14.9 0.0032 17.1 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain MyTH4 PF00784.12 KFO98894.1 - 0.015 15.2 0.3 0.036 13.9 0.1 1.6 2 0 0 2 2 2 0 MyTH4 domain zf-RING_2 PF13639.1 KFO98894.1 - 0.02 14.7 15.4 0.036 13.9 10.7 1.5 1 0 0 1 1 1 0 Ring finger domain UPF0104 PF03706.8 KFO98894.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF1049 PF06305.6 KFO98894.1 - 0.37 10.2 2.1 0.65 9.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Prok-RING_4 PF14447.1 KFO98894.1 - 3.2 7.3 12.7 8.7 5.9 8.8 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 VWA_3 PF13768.1 KFO98895.1 - 6.6e-30 103.8 0.0 1.2e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 KFO98895.1 - 8.9e-23 79.5 0.0 2.3e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KFO98895.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFO98895.1 - 2.7e-05 24.3 0.0 4.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Pox_LP_H2 PF03356.10 KFO98895.1 - 0.05 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Viral late protein H2 DEAD PF00270.24 KFO98896.1 - 2.8e-29 101.7 0.0 1.4e-28 99.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO98896.1 - 9.5e-26 89.4 2.2 2.9e-25 87.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UBX PF00789.15 KFO98897.1 - 7e-08 32.4 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Gag_p30 PF02093.11 KFO98898.1 - 8.5e-18 64.3 0.4 1.1e-17 63.9 0.3 1.1 1 0 0 1 1 1 1 Gag P30 core shell protein Gag_p24 PF00607.15 KFO98898.1 - 0.00072 19.1 0.0 0.0016 18.0 0.0 1.7 1 1 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) DUF577 PF04510.7 KFO98899.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF577) TUDOR PF00567.19 KFO98900.1 - 8.7e-22 77.2 0.0 2.3e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Tudor domain KH_1 PF00013.24 KFO98900.1 - 1.9e-08 33.8 0.0 3.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFO98900.1 - 2.8e-05 23.6 0.0 6.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 KH domain Agenet PF05641.7 KFO98900.1 - 0.0048 17.0 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Agenet domain KH_4 PF13083.1 KFO98900.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 KH domain RRM_6 PF14259.1 KFO98901.1 - 0.0063 16.4 0.1 0.015 15.3 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO98901.1 - 0.0073 15.9 0.5 0.015 14.8 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 KFO98901.1 - 0.036 14.1 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) MRP-S23 PF10484.4 KFO98902.1 - 4.9e-09 36.1 0.0 5.2e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 Ribosomal_S27 PF01599.14 KFO98902.1 - 0.075 12.8 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S27a CUE PF02845.11 KFO98903.1 - 2.5e-15 55.6 0.2 4.7e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 CUE domain zf-C2H2 PF00096.21 KFO98904.1 - 5.3e-18 64.2 49.9 0.00022 21.3 1.5 7.0 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO98904.1 - 1e-14 53.6 50.9 0.0034 17.6 1.1 6.9 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO98904.1 - 1.2e-13 50.6 62.0 0.00021 21.3 2.6 8.5 9 0 0 9 9 9 5 Zinc-finger double domain zf-Di19 PF05605.7 KFO98904.1 - 0.0012 18.9 33.7 0.27 11.3 4.6 4.5 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFO98904.1 - 0.16 12.0 31.8 1 9.5 0.0 6.2 2 1 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFO98904.1 - 0.17 12.1 0.2 0.17 12.1 0.1 6.7 7 0 0 7 7 7 0 Zinc-finger of C2H2 type DZR PF12773.2 KFO98904.1 - 0.21 11.4 21.9 0.56 10.0 0.6 4.7 3 1 1 4 4 4 0 Double zinc ribbon Elf1 PF05129.8 KFO98904.1 - 0.63 9.7 27.5 1 9.1 1.9 5.5 2 1 3 5 5 5 0 Transcription elongation factor Elf1 like DUF4407 PF14362.1 KFO98904.1 - 0.65 8.9 3.6 0.97 8.3 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XPA_N PF01286.13 KFO98904.1 - 5.2 6.8 22.9 0.72 9.5 0.1 5.3 7 0 0 7 7 7 0 XPA protein N-terminal Dynein_light PF01221.13 KFO98905.1 - 4.3e-46 154.8 1.7 4.7e-46 154.7 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TraH PF06122.6 KFO98905.1 - 0.034 12.9 0.1 0.038 12.7 0.0 1.0 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein HEXIM PF15313.1 KFO98905.1 - 0.05 13.7 0.5 0.06 13.5 0.3 1.1 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein WIYLD PF10440.4 KFO98905.1 - 0.054 13.4 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain HTH_33 PF13592.1 KFO98905.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Ground-like PF04155.13 KFO98905.1 - 0.079 13.2 0.1 0.098 12.9 0.1 1.3 1 1 0 1 1 1 0 Ground-like domain UCH PF00443.24 KFO98905.1 - 0.084 11.9 0.1 0.09 11.8 0.1 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ectatomin PF06457.6 KFO98905.1 - 0.13 12.0 0.2 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Ectatomin SpoIIIAH PF12685.2 KFO98905.1 - 0.26 10.7 2.2 0.32 10.4 1.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4042 PF13251.1 KFO98906.1 - 3.9e-68 228.5 0.1 3.9e-68 228.5 0.1 4.5 6 0 0 6 6 6 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.1 KFO98906.1 - 2.1e-27 95.2 6.3 1.7e-08 34.6 0.2 7.7 4 2 4 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 KFO98906.1 - 3.3e-17 62.4 17.5 0.008 16.6 0.4 8.9 9 0 0 9 9 9 4 HEAT-like repeat HEAT PF02985.17 KFO98906.1 - 1.9e-15 55.5 19.2 0.00016 21.4 0.0 10.0 11 0 0 11 11 11 4 HEAT repeat Adaptin_N PF01602.15 KFO98906.1 - 6.2e-06 24.8 8.6 0.048 11.9 0.1 4.4 4 1 0 4 4 4 3 Adaptin N terminal region HEAT_PBS PF03130.11 KFO98906.1 - 0.0009 19.4 8.0 0.81 10.3 0.0 6.9 6 1 0 6 6 6 1 PBS lyase HEAT-like repeat FANCI_S2 PF14676.1 KFO98906.1 - 0.0037 17.1 3.2 0.42 10.4 0.0 3.3 3 0 0 3 3 3 2 FANCI solenoid 2 Arm PF00514.18 KFO98906.1 - 0.024 14.4 26.6 0.037 13.8 0.1 7.8 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 KFO98906.1 - 0.029 13.5 0.8 0.77 8.8 0.0 3.1 3 0 0 3 3 3 0 Armadillo-like HNF-1B_C PF04812.8 KFO98907.1 - 1.7e-104 348.4 39.4 2.6e-104 347.8 27.3 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus HNF-1_N PF04814.8 KFO98907.1 - 6.3e-46 156.7 2.6 6.3e-46 156.7 1.8 2.0 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox PF00046.24 KFO98907.1 - 5.2e-06 25.9 0.9 5.2e-06 25.9 0.6 2.4 2 1 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFO98907.1 - 0.071 12.8 0.0 0.41 10.3 0.0 2.3 2 1 0 2 2 2 0 Homeobox KN domain DEAD PF00270.24 KFO98908.1 - 2.9e-38 131.0 0.0 7e-38 129.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO98908.1 - 8.1e-16 57.6 0.8 3.6e-15 55.5 0.1 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFO98908.1 - 1.1e-05 25.3 0.0 1.1e-05 25.3 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFO98908.1 - 1.2e-05 24.2 0.0 2.8e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 KFO98908.1 - 0.0031 17.2 0.0 0.012 15.3 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain EF-hand_4 PF12763.2 KFO98909.1 - 0.019 14.6 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand zf-rbx1 PF12678.2 KFO98909.1 - 0.054 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger SWIRM PF04433.12 KFO98910.1 - 4.3e-15 55.5 0.0 1.3e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KFO98910.1 - 9.4e-10 38.4 0.4 2e-09 37.3 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFO98910.1 - 4e-05 23.6 0.4 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 KFO98910.1 - 0.022 14.2 2.3 0.044 13.3 1.6 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type RPA_C PF08784.6 KFO98910.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal LIM PF00412.17 KFO98911.1 - 1.5e-32 111.4 25.0 1.5e-17 63.3 1.4 2.4 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFO98911.1 - 2.8e-10 39.6 0.2 5e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain SpoIIIAH PF12685.2 KFO98911.1 - 0.16 11.4 5.0 0.23 10.9 3.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TLV_coat PF00429.14 KFO98912.1 - 0.0034 15.9 1.7 0.0041 15.6 1.2 1.1 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) SecE PF00584.15 KFO98913.1 - 1.7e-15 56.3 0.1 2.1e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Pkinase_Tyr PF07714.12 KFO98914.1 - 6.9e-89 297.3 0.0 1e-88 296.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Recep_L_domain PF01030.19 KFO98914.1 - 3.7e-51 171.7 0.6 1e-26 93.1 0.0 2.5 2 0 0 2 2 2 2 Receptor L domain Pkinase PF00069.20 KFO98914.1 - 4.6e-43 147.2 0.0 6.9e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GF_recep_IV PF14843.1 KFO98914.1 - 6.7e-42 142.2 80.8 3e-32 111.0 17.8 5.0 2 2 0 3 3 3 2 Growth factor receptor domain IV Furin-like PF00757.15 KFO98914.1 - 6.5e-33 113.5 84.3 3.1e-30 104.8 29.4 4.2 2 1 2 4 4 4 3 Furin-like cysteine rich region APH PF01636.18 KFO98914.1 - 0.0092 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFO98914.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LANC_like PF05147.8 KFO98915.1 - 1.5e-97 326.3 0.3 1.7e-97 326.1 0.2 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.8 KFO98915.1 - 0.00039 19.7 0.1 0.74 9.0 0.0 3.1 3 0 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 KFO98915.1 - 0.00074 18.6 0.2 0.027 13.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KFO98915.1 - 0.004 15.4 0.7 0.086 11.0 0.1 2.5 2 2 1 3 3 3 1 Putative glycosyl hydrolase of unknown function (DUF1680) TPR_12 PF13424.1 KFO98915.1 - 0.01 15.7 0.7 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Prenyltrans_1 PF13243.1 KFO98915.1 - 0.15 12.0 0.3 6.6 6.7 0.0 2.7 3 0 0 3 3 3 0 Prenyltransferase-like WBP-1 PF11669.3 KFO98916.1 - 0.00021 21.3 3.6 0.00021 21.3 2.5 2.4 2 0 0 2 2 2 1 WW domain-binding protein 1 TMEM52 PF14979.1 KFO98916.1 - 0.062 13.2 10.6 0.061 13.2 1.2 2.1 2 0 0 2 2 2 0 Transmembrane 52 DUF3483 PF11982.3 KFO98916.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) CX PF01705.14 KFO98916.1 - 0.16 11.9 5.9 0.36 10.8 4.1 1.6 1 0 0 1 1 1 0 CX module Bax1-I PF01027.15 KFO98917.1 - 2.4e-39 135.0 14.4 2.4e-39 135.0 10.0 1.3 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.2 KFO98917.1 - 7.3e-13 48.2 10.8 1e-10 41.2 1.1 3.1 2 1 1 3 3 3 2 Bax inhibitor 1 like Neuregulin PF02158.10 KFO98918.1 - 3.5e-09 35.9 3.0 2.4e-08 33.1 1.2 2.5 2 1 0 2 2 2 1 Neuregulin family DUF1049 PF06305.6 KFO98918.1 - 0.0002 20.7 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) DUF2681 PF10883.3 KFO98918.1 - 0.039 14.1 0.9 0.09 12.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4366 PF14283.1 KFO98918.1 - 0.054 12.9 0.1 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) HSF_DNA-bind PF00447.12 KFO98919.1 - 2.2e-28 98.4 1.4 3.3e-28 97.9 1.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2365 PF10157.4 KFO98919.1 - 0.024 14.5 0.1 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) BOP1NT PF08145.7 KFO98920.1 - 3.5e-110 367.8 8.5 4.7e-110 367.3 5.9 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KFO98920.1 - 1.2e-28 97.9 10.0 5.4e-12 45.0 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat HEAT_2 PF13646.1 KFO98921.1 - 1e-15 57.7 2.7 0.54 10.5 0.0 8.0 5 3 1 7 7 7 5 HEAT repeats HEAT PF02985.17 KFO98921.1 - 7.3e-10 38.0 2.7 3.8 7.8 0.0 10.6 11 0 0 11 11 11 1 HEAT repeat HEAT_EZ PF13513.1 KFO98921.1 - 6e-07 29.7 12.3 0.99 9.9 0.0 9.6 12 1 1 13 13 13 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFO98921.1 - 0.003 17.9 0.0 3.8 7.9 0.0 4.3 2 2 1 3 3 3 1 Vacuolar 14 Fab1-binding region ParcG PF10274.4 KFO98921.1 - 0.019 14.8 2.1 0.89 9.4 0.0 4.3 4 0 0 4 4 4 0 Parkin co-regulated protein UME PF08064.8 KFO98921.1 - 0.042 13.8 9.0 0.23 11.4 0.0 5.2 5 0 0 5 5 5 0 UME (NUC010) domain DUF2411 PF10304.4 KFO98921.1 - 0.08 12.5 1.8 0.27 10.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2411) B12-binding PF02310.14 KFO98921.1 - 0.12 12.2 0.1 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain DUF4515 PF14988.1 KFO98922.1 - 2.3e-15 56.8 25.7 2.3e-15 56.8 17.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) Tropomyosin_1 PF12718.2 KFO98922.1 - 0.0044 16.8 33.0 0.035 13.9 15.7 2.2 1 1 1 2 2 2 2 Tropomyosin like ISG65-75 PF11727.3 KFO98922.1 - 0.083 11.9 18.8 0.028 13.4 3.9 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein COP23 PF14218.1 KFO98922.1 - 0.12 11.9 4.9 0.091 12.3 2.1 1.8 1 1 1 2 2 2 0 Circadian oscillating protein COP23 Baculo_PEP_C PF04513.7 KFO98922.1 - 0.33 10.7 9.6 0.35 10.7 3.5 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Adenylsucc_synt PF00709.16 KFO98922.1 - 0.5 8.9 8.2 0.27 9.8 0.9 2.2 1 1 1 2 2 2 0 Adenylosuccinate synthetase Cytochrom_C_2 PF01322.15 KFO98922.1 - 0.57 10.7 9.3 0.24 11.9 3.8 2.2 2 1 0 2 2 2 0 Cytochrome C' DUF2205 PF10224.4 KFO98922.1 - 0.64 9.6 17.2 0.031 13.8 1.6 3.0 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) GAS PF13851.1 KFO98922.1 - 1.1 8.4 34.3 1.2 8.3 21.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KFO98922.1 - 1.2 8.6 36.1 4.2 6.9 15.8 2.1 1 1 1 2 2 2 0 IncA protein Apolipoprotein PF01442.13 KFO98922.1 - 2.5 7.5 29.1 0.046 13.2 6.8 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF848 PF05852.6 KFO98922.1 - 4.8 7.0 20.3 0.25 11.2 8.8 2.2 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF342 PF03961.8 KFO98922.1 - 5.2 5.3 22.7 4.5 5.5 8.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 KFO98922.1 - 7.4 7.0 14.2 0.34 11.3 4.6 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 KFO98922.1 - 8.7 6.1 16.3 0.97 9.2 1.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DASH_Dad2 PF08654.5 KFO98922.1 - 8.7 6.4 13.1 0.086 12.8 2.5 2.7 3 2 1 4 4 4 0 DASH complex subunit Dad2 Pkinase PF00069.20 KFO98923.1 - 1.5e-62 211.1 0.0 2e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98923.1 - 1.1e-27 96.7 0.0 1.5e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO98923.1 - 0.0014 17.6 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO98923.1 - 0.055 12.5 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1669 PF07894.7 KFO98924.1 - 3.4e-105 351.3 0.8 3e-104 348.2 0.0 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFO98924.1 - 0.0037 17.0 0.2 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain LRR_4 PF12799.2 KFO98925.1 - 1.1e-47 158.9 55.8 2.1e-10 39.9 1.3 9.2 5 2 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO98925.1 - 1.3e-35 120.9 42.8 1.3e-08 34.4 3.2 6.7 3 2 4 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KFO98925.1 - 2.9e-24 81.3 52.1 0.02 14.8 0.2 14.4 15 0 0 15 15 15 12 Leucine Rich Repeat LRR_7 PF13504.1 KFO98925.1 - 1.5e-11 42.5 52.5 0.21 11.9 0.2 14.5 15 0 0 15 15 15 5 Leucine rich repeat LRR_9 PF14580.1 KFO98925.1 - 4.8e-06 26.2 11.9 0.0011 18.5 2.3 3.8 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 KFO98925.1 - 0.91 9.7 39.7 23 5.4 0.0 12.1 11 3 3 14 14 14 0 Leucine Rich repeat RRM_1 PF00076.17 KFO98926.1 - 3.7e-44 148.2 0.1 8.3e-19 66.9 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO98926.1 - 2.8e-31 107.3 0.0 5.1e-12 45.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO98926.1 - 1.6e-25 88.7 0.3 7.5e-10 38.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO98926.1 - 0.0048 16.7 0.0 1.6 8.5 0.0 2.9 2 0 0 2 2 2 2 RNA binding motif OB_RNB PF08206.6 KFO98926.1 - 0.018 14.5 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RseA_C PF03873.8 KFO98926.1 - 0.022 14.6 0.3 0.083 12.7 0.2 2.0 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Pkinase PF00069.20 KFO98927.1 - 7.8e-22 77.6 0.5 3.9e-21 75.3 0.3 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98927.1 - 6.4e-20 71.3 0.1 1.1e-19 70.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Plectin PF00681.15 KFO98928.1 - 8.5e-48 159.6 0.0 4.2e-19 67.8 0.0 5.1 3 2 2 5 5 5 4 Plectin repeat Homeobox_KN PF05920.6 KFO98932.1 - 4.5e-16 58.2 0.3 7.5e-16 57.5 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFO98932.1 - 6.5e-09 35.2 0.4 7.8e-09 35.0 0.3 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFO98932.1 - 0.004 16.1 0.1 0.008 15.2 0.0 1.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 KFO98932.1 - 0.021 14.9 0.1 0.035 14.2 0.0 1.4 1 1 0 1 1 1 0 Helicase associated domain MRP-S32 PF10210.4 KFO98932.1 - 0.068 13.4 0.8 0.085 13.1 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Homeobox_KN PF05920.6 KFO98934.1 - 1.3e-14 53.6 0.2 3.6e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFO98934.1 - 7.5e-08 31.8 0.6 1.6e-07 30.8 0.4 1.6 1 0 0 1 1 1 1 Homeobox domain MRP-S32 PF10210.4 KFO98934.1 - 0.00018 21.7 0.6 0.00038 20.7 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Homez PF11569.3 KFO98934.1 - 0.073 12.1 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez BSP_II PF05432.6 KFO98934.1 - 8.7 5.5 23.6 18 4.4 16.4 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Homeobox_KN PF05920.6 KFO98935.1 - 6.8e-16 57.6 0.2 1.2e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFO98935.1 - 4.8e-09 35.6 2.3 5.8e-09 35.4 1.6 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFO98935.1 - 0.0049 15.9 0.0 0.0092 15.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 KFO98935.1 - 0.021 14.9 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Helicase associated domain MRP-S32 PF10210.4 KFO98935.1 - 0.072 13.4 2.1 0.08 13.2 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Phage_P2_GpE PF06528.7 KFO98935.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Phage P2 GpE NUFIP1 PF10453.4 KFO98935.1 - 0.62 9.6 3.9 0.12 11.9 0.3 1.7 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CHCC PF10276.4 KFO98937.1 - 2.1e-19 69.0 0.7 2.5e-19 68.8 0.5 1.1 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KFO98937.1 - 0.036 13.7 0.1 0.04 13.5 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Acyltransferase PF01553.16 KFO98939.1 - 1.4e-16 60.1 0.0 2.4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_6 PF13405.1 KFO98939.1 - 4.3e-07 29.2 1.9 0.39 10.7 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFO98939.1 - 7.1e-07 28.7 5.3 0.00026 20.5 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 KFO98939.1 - 7e-06 26.0 3.7 0.0031 17.5 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFO98939.1 - 0.00024 20.1 6.6 0.27 10.6 0.3 4.1 4 0 0 4 4 4 2 EF hand TerB PF05099.8 KFO98939.1 - 0.17 11.6 2.1 43 3.8 0.0 3.4 2 1 1 3 3 3 0 Tellurite resistance protein TerB SNF PF00209.13 KFO98940.1 - 5.2e-178 592.7 28.8 6.7e-178 592.3 20.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.13 KFO98941.1 - 2.6e-177 590.4 28.1 3.3e-177 590.1 19.5 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2614 PF11023.3 KFO98941.1 - 0.072 12.8 0.6 0.53 10.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) PIN_3 PF13470.1 KFO98942.1 - 0.42 11.2 4.0 2 9.1 2.8 2.2 1 1 0 1 1 1 0 PIN domain AAA_23 PF13476.1 KFO98942.1 - 0.96 9.7 8.9 1.7 8.9 6.2 1.4 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 KFO98942.1 - 1.2 8.2 6.3 1.5 7.9 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAD_binding_2 PF00890.19 KFO98943.1 - 5e-127 424.1 2.4 6.2e-127 423.8 1.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KFO98943.1 - 9.9e-44 148.3 0.0 1.7e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KFO98943.1 - 1.8e-07 31.2 0.0 0.0055 16.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFO98943.1 - 3.3e-06 26.3 0.4 0.029 13.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFO98943.1 - 0.00016 20.7 0.1 0.0038 16.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KFO98943.1 - 0.00016 20.7 3.5 0.055 12.3 1.5 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFO98943.1 - 0.0048 15.9 0.2 0.0077 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFO98943.1 - 0.17 10.2 1.6 0.73 8.2 0.2 2.5 3 0 0 3 3 3 0 HI0933-like protein Lyase_1 PF00206.15 KFO98944.1 - 1.2e-122 408.9 0.2 1.6e-122 408.6 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KFO98944.1 - 2.7e-28 97.8 0.1 2.1e-27 94.9 0.0 2.3 2 0 0 2 2 2 1 Fumarase C C-terminus Snf7 PF03357.16 KFO98945.1 - 1.5e-50 170.9 20.3 1.7e-50 170.7 14.1 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 KFO98945.1 - 0.0021 18.2 3.4 0.0021 18.2 2.3 2.8 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein BCDHK_Adom3 PF10436.4 KFO98945.1 - 0.057 12.9 2.3 0.078 12.4 1.6 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Phage_lysozyme PF00959.14 KFO98945.1 - 0.067 13.4 0.8 0.1 12.9 0.6 1.4 1 0 0 1 1 1 0 Phage lysozyme Prefoldin_2 PF01920.15 KFO98945.1 - 0.081 12.6 22.0 0.52 10.0 0.6 3.4 2 1 1 3 3 3 0 Prefoldin subunit BTV_NS2 PF04514.7 KFO98945.1 - 0.14 10.9 11.1 0.18 10.6 7.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF45 PF01863.12 KFO98945.1 - 0.87 9.3 6.4 0.9 9.2 3.8 1.4 1 1 1 2 2 2 0 Protein of unknown function DUF45 DUF848 PF05852.6 KFO98945.1 - 0.88 9.4 10.4 0.37 10.6 4.7 2.1 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) GvpK PF05121.7 KFO98945.1 - 0.92 9.3 11.5 0.85 9.4 1.7 3.1 2 1 0 3 3 3 0 Gas vesicle protein K His_binding PF02098.11 KFO98945.1 - 0.99 9.2 4.6 1.8 8.3 3.2 1.5 1 1 0 1 1 1 0 Tick histamine binding protein PRA-PH PF01503.12 KFO98945.1 - 1.3 9.3 4.4 3.1 8.1 3.0 1.8 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF948 PF06103.6 KFO98945.1 - 1.9 8.3 5.9 1.7 8.5 2.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 KFO98945.1 - 4.9 6.6 11.9 31 4.0 8.3 2.0 1 1 0 1 1 1 0 IncA protein CorA PF01544.13 KFO98945.1 - 5.6 5.8 15.7 6.1 5.7 6.1 2.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF972 PF06156.8 KFO98945.1 - 6.6 7.1 13.9 24 5.3 2.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PEP-utilisers_N PF05524.8 KFO98945.1 - 7.8 6.3 10.1 1.2 8.9 0.8 2.4 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal BAG PF02179.11 KFO98946.1 - 1.2e-11 44.5 1.2 1.2e-11 44.5 0.8 2.0 1 1 1 2 2 2 1 BAG domain ubiquitin PF00240.18 KFO98946.1 - 4.9e-08 32.2 0.4 1.1e-07 31.1 0.0 1.8 2 0 0 2 2 1 1 Ubiquitin family PHTB1_C PF14728.1 KFO98946.1 - 3.2e-06 26.2 1.1 3.5e-06 26.0 0.8 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus V_ATPase_I PF01496.14 KFO98946.1 - 0.0049 14.8 1.3 0.0053 14.6 0.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family YPEB PF14620.1 KFO98946.1 - 0.0051 15.8 3.2 0.0051 15.8 2.2 1.5 1 1 1 2 2 2 1 YpeB sporulation HSBP1 PF06825.7 KFO98946.1 - 0.031 13.8 1.6 6.9 6.3 0.1 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Nup54 PF13874.1 KFO98946.1 - 0.041 13.5 4.0 1.1 8.9 0.1 2.5 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Sigma54_DBD PF04552.8 KFO98946.1 - 0.071 12.6 0.8 0.12 11.8 0.4 1.5 1 1 0 1 1 1 0 Sigma-54, DNA binding domain Uds1 PF15456.1 KFO98946.1 - 0.072 13.0 2.1 0.21 11.5 0.3 2.2 1 1 1 2 2 2 0 Up-regulated During Septation DUF4041 PF13250.1 KFO98946.1 - 0.077 12.5 0.5 3.7 7.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4041) Ubiquitin_2 PF14560.1 KFO98946.1 - 0.11 12.7 0.4 1.5 9.1 0.0 2.6 2 1 0 2 2 2 0 Ubiquitin-like domain Occludin_ELL PF07303.8 KFO98946.1 - 0.15 12.7 2.9 0.44 11.3 1.6 2.1 1 1 0 1 1 1 0 Occludin homology domain DUF2408 PF10303.4 KFO98946.1 - 0.17 12.0 4.3 0.32 11.1 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Spectrin PF00435.16 KFO98946.1 - 0.17 12.1 7.3 0.59 10.4 2.7 2.6 3 0 0 3 3 3 0 Spectrin repeat Baculo_PEP_C PF04513.7 KFO98946.1 - 0.24 11.2 1.4 0.63 9.8 0.6 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 KFO98946.1 - 0.24 10.6 7.5 0.091 12.0 3.3 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Fib_alpha PF08702.5 KFO98946.1 - 0.25 11.4 2.5 0.43 10.7 1.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MitMem_reg PF13012.1 KFO98946.1 - 0.28 11.2 2.5 2 8.5 1.2 2.5 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DASH_Duo1 PF08651.5 KFO98946.1 - 0.29 10.7 1.8 14 5.2 0.5 2.5 1 1 1 2 2 2 0 DASH complex subunit Duo1 NYD-SP28 PF14772.1 KFO98946.1 - 0.38 10.8 7.5 1.3 9.1 4.1 2.4 1 1 1 2 2 2 0 Sperm tail DUF342 PF03961.8 KFO98946.1 - 0.38 9.0 8.9 0.69 8.2 6.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) AATF-Che1 PF13339.1 KFO98946.1 - 0.44 10.6 4.3 0.73 9.9 2.3 1.8 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF1664 PF07889.7 KFO98946.1 - 0.48 10.2 3.8 1.5 8.6 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1319 PF07028.6 KFO98946.1 - 0.51 10.5 5.3 0.62 10.2 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Prefoldin PF02996.12 KFO98946.1 - 0.64 9.6 8.8 0.78 9.4 0.9 2.8 1 1 2 3 3 3 0 Prefoldin subunit WXG100 PF06013.7 KFO98946.1 - 0.65 10.0 5.9 8.6 6.4 0.0 2.9 3 1 1 4 4 2 0 Proteins of 100 residues with WXG IncA PF04156.9 KFO98946.1 - 0.83 9.2 8.4 1.2 8.6 5.8 1.6 1 1 0 1 1 1 0 IncA protein SPAM PF02090.10 KFO98946.1 - 0.95 9.4 5.4 16 5.4 0.0 2.8 3 0 0 3 3 3 0 Salmonella surface presentation of antigen gene type M protein Seryl_tRNA_N PF02403.17 KFO98946.1 - 0.98 9.4 11.4 1.2 9.2 5.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.14 KFO98946.1 - 1.1 8.8 8.0 2.1 7.8 5.5 1.6 1 1 0 1 1 1 0 GrpE Sec34 PF04136.10 KFO98946.1 - 1.1 8.8 5.5 3.6 7.2 1.9 2.2 1 1 0 2 2 2 0 Sec34-like family Laminin_II PF06009.7 KFO98946.1 - 2 8.1 6.8 1.2 8.8 0.7 2.7 2 1 1 3 3 3 0 Laminin Domain II KH_1 PF00013.24 KFO98948.1 - 1.1e-52 175.4 13.9 1.3e-17 63.1 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFO98948.1 - 3.8e-40 134.8 20.0 1.1e-13 50.4 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFO98948.1 - 5.5e-17 61.0 6.1 1.7e-05 24.3 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFO98948.1 - 5e-08 32.4 2.4 0.015 14.9 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFO98948.1 - 1.1e-05 25.1 5.7 0.32 10.8 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain DUF370 PF04025.7 KFO98948.1 - 0.017 15.1 0.9 3.6 7.7 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF370) Y_phosphatase PF00102.22 KFO98949.1 - 3.3e-79 265.5 1.5 6.9e-79 264.4 1.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_C PF09380.5 KFO98949.1 - 8.9e-23 80.3 1.6 2.3e-22 78.9 1.1 1.8 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFO98949.1 - 6.4e-21 74.8 0.1 1.6e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 FERM central domain PDZ PF00595.19 KFO98949.1 - 2.7e-20 72.3 0.1 7.4e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) FERM_N PF09379.5 KFO98949.1 - 2.4e-19 69.1 0.0 5.4e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain DSPc PF00782.15 KFO98949.1 - 1e-05 25.0 0.1 2.6e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFO98949.1 - 0.00052 20.0 0.3 0.0013 18.8 0.2 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFO98949.1 - 0.0016 18.7 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Trm112p PF03966.11 KFO98949.1 - 0.015 15.6 0.0 1.9 8.8 0.0 3.2 1 1 0 1 1 1 0 Trm112p-like protein PDZ_2 PF13180.1 KFO98949.1 - 0.052 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 PDZ domain DOMON PF03351.12 KFO98951.1 - 1.2e-23 83.3 0.0 1.5e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 DOMON domain UPF0118 PF01594.11 KFO98952.1 - 1.2e-10 40.9 29.9 6.4e-10 38.5 13.0 3.8 4 1 0 4 4 4 2 Domain of unknown function DUF20 YL1_C PF08265.6 KFO98953.1 - 8.6e-13 47.6 0.1 8.6e-13 47.6 0.0 2.1 3 0 0 3 3 3 1 YL1 nuclear protein C-terminal domain Glycos_transf_2 PF00535.21 KFO98954.1 - 1.6e-34 119.0 0.0 2.7e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFO98954.1 - 1.5e-28 99.2 3.4 2.5e-28 98.5 2.0 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFO98954.1 - 4.4e-11 43.0 0.0 6.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFO98954.1 - 7.6e-07 28.5 0.1 1.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.1 KFO98954.1 - 6.6e-06 26.4 0.1 0.0036 17.6 0.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_tranf_2_2 PF10111.4 KFO98954.1 - 6.5e-05 22.1 0.0 0.00056 19.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KFO98954.1 - 0.026 14.2 0.1 0.064 12.9 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Rpr2 PF04032.11 KFO98955.1 - 0.053 13.3 0.9 0.053 13.3 0.7 2.0 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-U1 PF06220.7 KFO98955.1 - 0.56 9.8 3.1 1.4 8.5 0.1 2.8 3 0 0 3 3 3 0 U1 zinc finger CTD_bind PF04818.8 KFO98956.1 - 1.1e-25 89.6 0.4 4e-25 87.8 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase II-binding domain. PhoU PF01895.14 KFO98956.1 - 0.051 14.0 1.1 1.2 9.6 0.5 2.4 2 0 0 2 2 2 0 PhoU domain DUF4140 PF13600.1 KFO98956.1 - 5.9 7.3 6.6 40 4.7 2.6 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FH2 PF02181.18 KFO98957.1 - 3.3e-87 292.7 8.1 3.3e-87 292.7 5.6 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain V-set PF07686.12 KFO98958.1 - 4.5e-11 42.6 0.2 1e-10 41.4 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFO98958.1 - 9e-09 35.0 1.2 1e-07 31.7 0.8 2.2 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFO98958.1 - 1.6e-05 24.9 0.4 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 KFO98958.1 - 0.00012 22.0 0.4 0.00033 20.7 0.3 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.11 KFO98958.1 - 0.056 11.7 0.1 0.07 11.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Cobl PF09469.5 KFO98959.1 - 5.3e-29 100.0 0.6 5.3e-29 100.0 0.4 2.2 3 0 0 3 3 3 1 Cordon-bleu ubiquitin-like domain RBD PF02196.10 KFO98959.1 - 0.00077 19.1 0.3 0.014 15.1 0.0 2.5 2 1 0 2 2 2 1 Raf-like Ras-binding domain Rad60-SLD PF11976.3 KFO98959.1 - 0.0009 18.8 0.0 0.0026 17.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 KFO98959.1 - 0.0021 17.9 0.2 0.041 13.8 0.0 2.5 2 0 0 2 2 2 1 GLUT4 regulating protein TUG WH2 PF02205.15 KFO98960.1 - 3.2e-15 55.1 3.9 0.00012 21.5 0.0 3.6 3 0 0 3 3 3 3 WH2 motif BPS PF08947.5 KFO98961.1 - 4.9e-30 102.8 0.6 9.1e-30 102.0 0.4 1.5 1 0 0 1 1 1 1 BPS (Between PH and SH2) SH2 PF00017.19 KFO98961.1 - 1e-15 57.3 0.0 2.2e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain RA PF00788.18 KFO98961.1 - 7.4e-12 45.6 0.2 3.3e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFO98961.1 - 3.6e-09 36.7 0.1 8.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFO98961.1 - 0.044 13.9 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Pyridoxal_deC PF00282.14 KFO98962.1 - 5.5e-166 551.5 0.0 6.7e-166 551.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFO98962.1 - 0.00042 19.5 0.0 0.00075 18.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFO98962.1 - 0.0047 15.9 0.1 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II AAA PF00004.24 KFO98963.1 - 6.4e-38 129.9 0.0 1.1e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFO98963.1 - 1.5e-06 27.9 0.0 6.9e-06 25.8 0.0 2.2 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 KFO98963.1 - 2.6e-06 26.6 0.0 4.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFO98963.1 - 0.0018 18.4 0.5 0.15 12.2 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFO98963.1 - 0.0022 17.7 0.1 0.011 15.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFO98963.1 - 0.0026 17.6 0.0 0.0066 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFO98963.1 - 0.0081 16.1 1.1 0.38 10.7 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 KFO98963.1 - 0.011 15.2 0.2 0.039 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KFO98963.1 - 0.024 13.3 0.1 0.062 12.0 0.0 1.5 1 1 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 KFO98963.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KFO98963.1 - 0.08 12.3 0.5 4.2 6.7 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 KFO98963.1 - 0.082 12.6 1.2 0.24 11.1 0.3 2.1 2 0 0 2 2 2 0 Part of AAA domain zf-H2C2_2 PF13465.1 KFO98964.1 - 1.8e-22 78.4 33.0 3.5e-07 30.1 0.1 6.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFO98964.1 - 1.2e-15 56.8 45.3 2.2e-05 24.5 0.3 6.7 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO98964.1 - 1e-07 31.7 43.6 0.00047 20.2 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO98964.1 - 0.0022 18.1 27.2 0.24 11.5 0.0 5.9 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO98964.1 - 0.065 13.1 34.9 0.064 13.1 2.6 6.6 6 1 0 6 6 6 0 C2H2-type zinc finger GAGA PF09237.6 KFO98964.1 - 0.093 12.3 0.1 0.093 12.3 0.1 2.5 2 1 1 3 3 3 0 GAGA factor zf-met PF12874.2 KFO98964.1 - 0.15 12.2 0.1 0.15 12.2 0.1 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFO98964.1 - 8 6.9 33.2 0.3 11.3 1.6 5.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain AKAP95 PF04988.7 KFO98964.1 - 8.2 6.1 11.0 4 7.1 1.4 3.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Sp38 PF07354.7 KFO98966.1 - 5.2e-88 294.2 4.0 6.3e-88 293.9 2.8 1.1 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) DUF2701 PF10857.3 KFO98966.1 - 0.0042 16.8 0.2 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2701) VWC PF00093.13 KFO98967.1 - 4.7e-12 45.8 50.6 1.3e-09 37.9 11.3 3.1 3 0 0 3 3 3 3 von Willebrand factor type C domain Pacifastin_I PF05375.8 KFO98967.1 - 4.8e-05 22.7 4.3 4.8e-05 22.7 3.0 4.3 4 1 0 4 4 4 2 Pacifastin inhibitor (LCMII) TILa PF12714.2 KFO98967.1 - 0.019 14.7 8.4 0.019 14.7 5.8 3.9 3 3 0 3 3 3 0 TILa domain Yae1_N PF09811.4 KFO98968.1 - 2.8e-20 71.5 64.3 1.5e+04 -25.0 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal PNP_UDP_1 PF01048.15 KFO98972.1 - 2.4e-23 82.3 0.0 2.8e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4483 PF14825.1 KFO98973.1 - 0.028 14.0 2.0 0.065 12.9 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4483) Med10 PF09748.4 KFO98974.1 - 7.7e-42 142.1 0.6 8.7e-42 141.9 0.4 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex IL12 PF03039.9 KFO98974.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Synaptonemal_3 PF15191.1 KFO98974.1 - 0.22 11.2 1.2 31 4.3 0.1 2.9 1 1 1 3 3 3 0 Synaptonemal complex central element protein 3 UQ_con PF00179.21 KFO98975.1 - 4.5e-06 26.1 0.0 6.5e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFO98975.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Nol1_Nop2_Fmu PF01189.12 KFO98976.1 - 1.3e-36 126.4 0.1 8.3e-20 71.3 0.0 3.3 2 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 KFO98976.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Steroid_dh PF02544.11 KFO98977.1 - 7.1e-43 145.9 0.5 8.1e-43 145.7 0.3 1.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KFO98977.1 - 4.8e-06 26.0 0.1 5.2e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KFO98977.1 - 0.18 11.9 2.0 0.73 9.9 0.4 2.2 1 1 1 2 2 2 0 Phospholipid methyltransferase Guanylate_cyc PF00211.15 KFO98978.1 - 2.8e-121 401.6 0.6 2.8e-65 219.1 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 KFO98978.1 - 9.2e-27 93.3 0.4 1.8e-26 92.3 0.3 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.9 KFO98978.1 - 0.0005 19.3 1.1 0.031 13.4 0.3 2.4 2 0 0 2 2 2 2 Heme NO binding associated FAST_1 PF06743.10 KFO98979.1 - 5.1e-22 77.3 2.4 5.1e-22 77.3 1.6 3.7 2 1 1 3 3 3 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.7 KFO98979.1 - 4.7e-17 62.1 0.1 2e-16 60.1 0.0 2.2 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 2 RAP PF08373.5 KFO98979.1 - 1.5e-14 53.4 0.0 3.3e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 RAP domain FANCI_S2 PF14676.1 KFO98979.1 - 0.19 11.5 5.2 2 8.2 0.6 3.6 2 1 1 3 3 3 0 FANCI solenoid 2 FAD_binding_1 PF00667.15 KFO98980.1 - 3e-45 154.3 0.0 4.7e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFO98980.1 - 9e-30 103.5 0.0 1.7e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFO98980.1 - 5.9e-13 49.3 0.0 1.4e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFO98980.1 - 2.9e-06 27.3 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 KFO98980.1 - 0.052 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Lamprin PF06403.6 KFO98981.1 - 0.093 12.4 0.0 0.38 10.4 0.0 1.8 1 1 0 1 1 1 0 Lamprin Sema PF01403.14 KFO98982.1 - 4.2e-110 368.2 0.6 6e-110 367.7 0.4 1.1 1 0 0 1 1 1 1 Sema domain TSP_1 PF00090.14 KFO98982.1 - 5.1e-42 141.7 96.1 1.1e-11 44.6 5.7 7.8 7 1 0 7 7 7 5 Thrombospondin type 1 domain Methyltransf_26 PF13659.1 KFO98984.1 - 2.7e-06 27.4 0.0 4.8e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO98984.1 - 2.7e-06 27.2 0.0 3.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO98984.1 - 2.7e-06 27.9 0.0 4.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFO98984.1 - 0.00075 18.9 0.0 0.00098 18.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KFO98984.1 - 0.0015 18.1 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 KFO98984.1 - 0.019 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PrmA PF06325.8 KFO98984.1 - 0.03 13.4 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFO98984.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 KFO98984.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.13 KFO98984.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Cpn60_TCP1 PF00118.19 KFO98985.1 - 5.4e-147 490.3 1.8 6.7e-147 490.0 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 KFO98986.1 - 4.1e-44 150.6 0.0 5.1e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO98986.1 - 1.8e-22 79.6 0.0 2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO98986.1 - 9.6e-07 28.0 0.0 8e-06 25.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DLH PF01738.13 KFO98987.1 - 2.1e-42 144.8 0.0 2.4e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFO98987.1 - 1.5e-12 47.4 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFO98987.1 - 2.5e-09 36.9 0.0 3.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFO98987.1 - 5.8e-08 32.8 0.0 0.00088 19.2 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFO98987.1 - 3.1e-06 26.5 0.3 5.3e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 KFO98987.1 - 0.0005 19.5 0.1 0.0016 17.8 0.1 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 KFO98987.1 - 0.0022 17.5 0.3 0.084 12.4 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1935 PF09149.5 KFO98987.1 - 0.039 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Abhydrolase_3 PF07859.8 KFO98987.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KFO98988.1 - 1.8e-33 115.6 0.0 2.1e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFO98988.1 - 1e-12 47.9 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFO98988.1 - 4.9e-10 39.6 0.0 5.7e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFO98988.1 - 7.6e-10 38.5 0.0 9.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KFO98988.1 - 9.8e-08 31.4 0.1 0.004 16.3 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFO98988.1 - 1.3e-07 31.4 0.2 0.00013 21.5 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFO98988.1 - 2.1e-05 24.1 0.0 0.027 14.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KFO98988.1 - 0.00024 20.0 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF915 PF06028.6 KFO98988.1 - 0.0025 16.9 0.0 0.0049 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.8 KFO98988.1 - 0.0027 17.1 0.1 0.018 14.5 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Chlorophyllase PF07224.6 KFO98988.1 - 0.0055 15.5 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase BAAT_C PF08840.6 KFO98988.1 - 0.1 12.2 0.3 1.3 8.6 0.1 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal RINGv PF12906.2 KFO98989.1 - 1.3e-14 53.9 9.0 2.8e-14 52.8 6.3 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KFO98989.1 - 0.16 11.8 8.7 0.48 10.2 6.1 1.9 1 0 0 1 1 1 0 Ring finger domain Ank_5 PF13857.1 KFO98992.1 - 4.6e-16 58.4 2.3 5.3e-06 26.5 0.2 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFO98992.1 - 2.2e-15 56.7 0.1 7.1e-15 55.1 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO98992.1 - 5e-14 52.3 0.4 1.4e-06 28.6 0.5 3.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFO98992.1 - 3.3e-13 48.7 0.2 3.2e-06 26.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KFO98992.1 - 1.9e-11 43.0 0.5 0.0023 17.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat DAP PF15228.1 KFO98993.1 - 1.7e-25 89.5 8.1 1.9e-25 89.4 5.6 1.0 1 0 0 1 1 1 1 Death-associated protein Arm PF00514.18 KFO98994.1 - 2.2e-46 154.1 9.6 4e-09 35.9 0.0 9.0 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFO98994.1 - 9.4e-11 41.8 0.8 8.4e-05 22.7 0.0 3.4 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KFO98994.1 - 4e-05 23.3 3.2 0.91 9.7 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.15 KFO98994.1 - 0.0065 14.8 0.0 0.37 9.0 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 KFO98994.1 - 0.017 15.5 4.0 37 4.9 0.1 5.0 4 1 0 4 4 4 0 HEAT-like repeat Mak16 PF04874.9 KFO98996.1 - 5.5e-30 103.4 18.3 5.5e-30 103.4 12.7 2.6 2 1 1 3 3 3 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 KFO98996.1 - 1.2e-26 93.4 0.1 2.1e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Na_trans_assoc PF06512.8 KFO98996.1 - 0.035 14.0 11.9 0.043 13.7 8.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.7 KFO98996.1 - 0.064 11.1 23.0 0.08 10.8 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.6 KFO98996.1 - 0.42 9.8 17.4 0.66 9.2 12.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2201_N PF13203.1 KFO98996.1 - 0.58 9.2 7.9 0.88 8.6 5.4 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.2 KFO98996.1 - 1.1 6.8 8.9 1.3 6.6 6.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.5 KFO98996.1 - 1.2 8.2 21.7 1.6 7.8 15.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1510 PF07423.6 KFO98996.1 - 3.1 7.1 16.6 5.1 6.3 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KFO98996.1 - 8.9 4.2 17.4 13 3.7 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2454 PF10521.4 KFO98997.1 - 0.082 11.8 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) zf-RING_2 PF13639.1 KFO98998.1 - 3.9e-06 26.5 0.6 3.9e-06 26.5 0.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFO98998.1 - 0.011 15.3 0.3 0.011 15.3 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO98998.1 - 0.016 14.8 0.4 0.032 13.9 0.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFO98998.1 - 0.035 14.1 0.3 0.089 12.8 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO98998.1 - 0.048 13.3 0.5 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4199 PF13858.1 KFO98998.1 - 0.085 12.7 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DSPc PF00782.15 KFO98999.1 - 3.1e-30 104.4 0.0 3.8e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO98999.1 - 0.00017 21.0 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ZU5 PF00791.15 KFO99000.1 - 2.4e-30 104.2 0.0 4.5e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain I-set PF07679.11 KFO99000.1 - 1.6e-12 47.0 0.0 1.5e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99000.1 - 6.2e-12 45.4 0.0 5.7e-10 39.1 0.0 2.8 2 0 0 2 2 2 1 Immunoglobulin domain Death PF00531.17 KFO99000.1 - 3.1e-11 42.8 0.0 6.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Death domain TSP_1 PF00090.14 KFO99000.1 - 2.5e-10 40.2 24.0 6.2e-07 29.4 6.6 2.9 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_3 PF13927.1 KFO99000.1 - 1.2e-05 25.7 0.0 6.1e-05 23.4 0.0 2.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO99000.1 - 3.9e-05 23.7 0.0 0.00015 21.7 0.0 2.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO99000.1 - 0.0074 16.1 0.0 0.021 14.6 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin V-set domain DUF3040 PF11239.3 KFO99000.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Band_7 PF01145.20 KFO99002.1 - 1.4e-05 25.1 1.1 1.4e-05 25.1 0.8 2.1 1 1 0 2 2 2 1 SPFH domain / Band 7 family DUF4346 PF14251.1 KFO99002.1 - 0.032 13.9 1.4 0.067 12.9 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) Ala_racemase_N PF01168.15 KFO99003.1 - 3.5e-41 141.1 0.0 4.4e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TFIIB PF00382.14 KFO99004.1 - 0.00011 21.9 0.0 0.37 10.6 0.0 2.7 2 1 0 2 2 2 2 Transcription factor TFIIB repeat Ycf1 PF05758.7 KFO99004.1 - 0.00088 17.1 1.0 0.001 16.9 0.7 1.1 1 0 0 1 1 1 1 Ycf1 Atrophin-1 PF03154.10 KFO99004.1 - 0.0092 14.1 15.0 0.013 13.7 10.4 1.2 1 0 0 1 1 1 1 Atrophin-1 family U79_P34 PF03064.11 KFO99004.1 - 0.03 13.8 12.4 0.049 13.1 8.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NESP55 PF06390.7 KFO99004.1 - 0.093 12.0 11.1 0.16 11.3 7.7 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RNase_H2-Ydr279 PF09468.5 KFO99004.1 - 0.13 11.4 10.0 0.21 10.7 6.9 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 KFO99004.1 - 0.2 9.6 8.2 0.28 9.1 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 KFO99004.1 - 0.39 10.4 5.3 0.65 9.7 3.7 1.3 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 KFO99004.1 - 0.58 9.1 3.2 1.1 8.2 2.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S49_N PF08496.5 KFO99004.1 - 0.65 9.7 14.2 1.2 8.9 9.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Vfa1 PF08432.5 KFO99004.1 - 1.4 8.9 20.5 2.4 8.1 14.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YqfQ PF14181.1 KFO99004.1 - 1.5 8.7 14.9 2.8 7.9 10.3 1.3 1 0 0 1 1 1 0 YqfQ-like protein MIP-T3 PF10243.4 KFO99004.1 - 2.5 6.4 28.8 0.045 12.2 15.2 1.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 AAA_11 PF13086.1 KFO99004.1 - 2.5 7.5 7.4 5.3 6.5 5.1 1.5 1 0 0 1 1 1 0 AAA domain Sec62 PF03839.11 KFO99004.1 - 3.2 7.1 16.8 5 6.4 11.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Rtf2 PF04641.7 KFO99004.1 - 3.6 6.7 20.5 17 4.5 11.8 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger Trypan_PARP PF05887.6 KFO99004.1 - 3.9 7.2 12.4 7.1 6.4 8.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NARP1 PF12569.3 KFO99004.1 - 4 6.0 15.8 7.2 5.2 11.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1682 PF07946.9 KFO99004.1 - 4.7 5.9 20.1 8 5.2 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1510 PF07423.6 KFO99004.1 - 6.1 6.1 19.4 9.2 5.5 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nucleoplasmin PF03066.10 KFO99005.1 - 4e-13 49.1 0.2 4.3e-13 49.0 0.2 1.0 1 0 0 1 1 1 1 Nucleoplasmin eIF_4EBP PF05456.6 KFO99006.1 - 2.5e-17 62.6 0.0 2.6e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TGF_beta PF00019.15 KFO99007.1 - 8.7e-29 99.8 0.8 1.5e-28 99.1 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFO99007.1 - 1.7e-13 50.4 0.0 3.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 TGF-beta propeptide SPRY PF00622.23 KFO99008.1 - 4.8e-14 52.5 0.6 2.9e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 SPRY domain EPTP PF03736.12 KFO99009.1 - 4.4e-84 276.0 12.6 1.6e-12 46.9 0.0 7.4 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 KFO99009.1 - 1.7e-21 75.6 10.4 1.3e-12 47.2 3.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_5 PF13306.1 KFO99009.1 - 8.1e-09 35.2 0.1 1.8e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFO99009.1 - 8.8e-09 34.7 9.2 0.00083 18.9 2.4 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO99009.1 - 1.4e-07 30.5 10.0 0.016 15.1 0.4 4.9 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_9 PF14580.1 KFO99009.1 - 0.00042 19.9 0.1 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KFO99009.1 - 0.031 14.4 11.6 0.49 10.8 0.6 4.8 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KFO99009.1 - 8.2 6.8 16.7 12 6.3 1.2 4.5 3 1 1 4 4 4 0 Leucine Rich repeat 7tm_1 PF00001.16 KFO99010.1 - 9.1e-84 280.5 6.2 1.1e-83 280.3 4.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO99010.1 - 9.8e-19 67.5 4.5 1.3e-18 67.1 3.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFO99010.1 - 2e-07 30.4 0.4 3.6e-07 29.6 0.3 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFO99010.1 - 1.6e-06 27.4 7.9 3.1e-06 26.5 5.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Piwi PF02171.12 KFO99011.1 - 5e-54 183.3 0.4 1.4e-32 112.9 0.0 2.2 1 1 1 2 2 2 2 Piwi domain Zip PF02535.17 KFO99012.1 - 1.3e-70 237.9 4.7 2.7e-70 236.8 2.7 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter TauE PF01925.14 KFO99012.1 - 0.015 14.7 5.5 0.59 9.5 1.9 2.4 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE SH3_2 PF07653.12 KFO99013.1 - 1.6e-15 56.2 0.0 1.8e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFO99013.1 - 1.4e-14 53.3 0.0 1.6e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFO99013.1 - 4.1e-14 51.7 0.0 5e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 SH3 domain MSV199 PF10553.4 KFO99014.1 - 0.0074 16.1 0.5 0.0093 15.8 0.3 1.1 1 0 0 1 1 1 1 MSV199 domain Ran-binding PF05508.6 KFO99014.1 - 0.022 13.6 0.5 0.025 13.4 0.4 1.1 1 0 0 1 1 1 0 RanGTP-binding protein DUF1336 PF07059.7 KFO99014.1 - 0.063 12.6 0.1 0.069 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) UPF0158 PF03682.8 KFO99014.1 - 0.064 12.8 0.1 0.069 12.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF3446 PF11928.3 KFO99015.1 - 3.2e-08 33.6 0.4 6.1e-08 32.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) MACPF PF01823.14 KFO99016.1 - 1.4e-06 28.1 1.7 1.7e-06 27.8 0.0 2.1 3 0 0 3 3 3 1 MAC/Perforin domain Microtub_assoc PF07989.6 KFO99017.1 - 1.3e-25 89.0 10.3 1.3e-25 89.0 7.2 10.6 10 2 0 10 10 10 2 Microtubule associated Reo_sigmaC PF04582.7 KFO99017.1 - 0.00025 20.3 4.8 0.00025 20.3 3.3 6.6 5 1 1 7 7 7 1 Reovirus sigma C capsid protein Laminin_EGF PF00053.19 KFO99019.1 - 9.9e-39 131.0 103.6 2.9e-09 36.7 12.6 5.3 5 0 0 5 5 5 5 Laminin EGF-like (Domains III and V) cEGF PF12662.2 KFO99019.1 - 0.0018 17.8 2.7 0.0018 17.8 1.9 9.0 7 2 1 8 8 8 1 Complement Clr-like EGF-like hEGF PF12661.2 KFO99019.1 - 0.035 14.2 2.4 0.035 14.2 1.7 10.1 12 0 0 12 12 12 0 Human growth factor-like EGF TMEM154 PF15102.1 KFO99019.1 - 0.044 13.4 0.3 0.078 12.6 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family SCF PF02404.10 KFO99019.1 - 0.056 12.6 0.2 0.082 12.0 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor ApoM PF11032.3 KFO99020.1 - 3.7e-11 42.9 0.0 4.3e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Apolipoprotein M (ApoM) Lipocalin PF00061.18 KFO99020.1 - 2.5e-07 30.7 0.1 4e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Flagellar_rod PF05149.7 KFO99020.1 - 0.057 12.6 0.1 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Paraflagellar rod protein Mito_carr PF00153.22 KFO99021.1 - 4.2e-75 247.5 2.8 1.5e-25 88.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KFO99021.1 - 1.6e-14 53.8 1.7 4.5e-10 39.5 0.1 2.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFO99021.1 - 8e-14 49.8 2.3 0.0012 18.0 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFO99021.1 - 1.4e-11 43.2 2.2 0.00035 20.1 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFO99021.1 - 1.6e-10 40.3 0.5 0.00037 20.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFO99021.1 - 6.8e-06 25.1 0.5 0.42 10.0 0.1 3.4 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 KFO99021.1 - 0.00041 20.3 1.3 0.001 19.0 0.9 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KFO99021.1 - 0.0013 18.3 0.8 1.4 8.6 0.0 3.5 2 1 1 3 3 3 2 EF hand EF-hand_4 PF12763.2 KFO99021.1 - 0.076 12.7 2.7 0.76 9.5 0.1 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand UBN2 PF14223.1 KFO99021.1 - 0.079 12.7 0.6 0.86 9.4 0.1 2.2 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type CDC37_C PF08564.5 KFO99021.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Cdc37 C terminal domain NT-C2 PF10358.4 KFO99022.1 - 4.3e-31 107.3 0.3 1.3e-30 105.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DPM2 PF07297.7 KFO99023.1 - 1.6e-22 79.5 0.8 1.7e-22 79.4 0.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TMEM154 PF15102.1 KFO99023.1 - 0.027 14.1 0.2 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family S1FA PF04689.8 KFO99023.1 - 0.034 14.0 0.2 0.041 13.7 0.2 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA FixQ PF05545.6 KFO99023.1 - 0.051 13.2 0.8 0.074 12.7 0.5 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PepSY_TM_2 PF13703.1 KFO99023.1 - 0.086 13.0 0.2 0.092 12.9 0.2 1.0 1 0 0 1 1 1 0 PepSY-associated TM helix DUF3377 PF11857.3 KFO99023.1 - 0.097 12.3 0.6 0.1 12.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3278 PF11683.3 KFO99023.1 - 0.11 12.5 0.2 0.12 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Glyco_transf_29 PF00777.13 KFO99024.1 - 3.1e-29 101.9 0.0 3.8e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Pkinase PF00069.20 KFO99025.1 - 1.3e-71 240.7 0.0 1.6e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99025.1 - 6e-34 117.2 0.0 7.8e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO99025.1 - 0.00024 20.1 0.1 0.26 10.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KFO99025.1 - 0.5 9.6 4.6 0.22 10.8 0.8 2.0 2 1 0 2 2 2 0 RIO1 family SH2 PF00017.19 KFO99026.1 - 3e-15 55.7 0.1 6.2e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 SH2 domain RasGEF PF00617.14 KFO99026.1 - 1.4e-13 51.0 0.0 3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Torsin PF06309.6 KFO99027.1 - 7.8e-39 132.4 0.0 1.5e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_2 PF07724.9 KFO99027.1 - 0.00026 20.9 0.0 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KFO99027.1 - 0.0083 16.3 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KFO99027.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KFO99027.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KFO99027.1 - 0.14 12.3 0.1 4 7.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFO99027.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Pept_tRNA_hydro PF01195.14 KFO99028.1 - 1.7e-36 125.4 0.0 2e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Glyco_transf_25 PF01755.12 KFO99029.1 - 1.2e-28 100.1 0.0 7.3e-27 94.3 0.0 2.6 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.1 KFO99029.1 - 1.7e-08 34.6 0.1 3.9e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.9 KFO99029.1 - 0.0029 16.8 0.0 0.0059 15.7 0.0 1.5 1 1 0 1 1 1 1 Anp1 MT-A70 PF05063.9 KFO99029.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 MT-A70 Urm1 PF09138.6 KFO99030.1 - 4.4e-38 129.3 0.0 4.8e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KFO99030.1 - 0.00082 19.7 0.0 0.00097 19.5 0.0 1.1 1 0 0 1 1 1 1 ThiS family AMP-binding PF00501.23 KFO99031.1 - 8e-73 245.2 0.0 9.5e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO99031.1 - 5.3e-05 24.0 0.0 0.0001 23.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Coq4 PF05019.8 KFO99032.1 - 1.4e-96 321.7 0.0 1.6e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rnk_N PF14760.1 KFO99032.1 - 0.044 13.8 0.1 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Rnk N-terminus TruB_N PF01509.13 KFO99033.1 - 2.3e-19 70.0 0.0 3.1e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Swi5 PF07061.6 KFO99034.1 - 4.6e-23 80.8 0.8 5e-23 80.6 0.6 1.0 1 0 0 1 1 1 1 Swi5 DUF904 PF06005.7 KFO99034.1 - 0.0058 16.9 1.7 0.0082 16.4 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 KFO99034.1 - 0.006 16.6 0.2 0.0083 16.2 0.1 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 KFO99034.1 - 0.033 13.2 0.1 0.038 13.0 0.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 KFO99034.1 - 0.078 12.9 0.1 0.086 12.8 0.1 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1192 PF06698.6 KFO99034.1 - 0.44 10.3 4.3 3.1 7.6 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) GOLGA2L5 PF15070.1 KFO99035.1 - 5e-241 801.5 86.4 5e-241 801.5 59.9 2.4 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 ADP_ribosyl_GH PF03747.9 KFO99035.1 - 1.5 8.4 0.0 1.5 8.4 0.0 2.7 3 2 0 3 3 3 0 ADP-ribosylglycohydrolase Dynamin_M PF01031.15 KFO99036.1 - 1.5e-101 339.0 5.9 1.5e-101 339.0 4.1 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFO99036.1 - 1.4e-41 142.1 0.0 4.5e-41 140.4 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFO99036.1 - 9e-27 92.8 2.5 2.3e-26 91.4 1.7 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 KFO99036.1 - 1.9e-10 40.8 0.9 3.9e-10 39.8 0.7 1.5 1 0 0 1 1 1 1 PH domain Ldh_1_N PF00056.18 KFO99036.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF605 PF04652.11 KFO99036.1 - 7.4 5.8 7.3 11 5.2 5.0 1.2 1 0 0 1 1 1 0 Vta1 like zf-C2H2_jaz PF12171.3 KFO99037.1 - 1.3e-05 25.2 29.9 0.00014 21.8 0.3 4.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO99037.1 - 2e-05 24.6 28.5 0.0014 18.7 4.7 4.5 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFO99037.1 - 0.032 14.3 1.0 0.032 14.3 0.7 4.1 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 KFO99037.1 - 0.12 12.1 15.6 0.37 10.5 8.1 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Myc_N PF01056.13 KFO99037.1 - 0.26 10.3 6.3 0.56 9.3 4.3 1.5 1 0 0 1 1 1 0 Myc amino-terminal region zf-C2H2 PF00096.21 KFO99037.1 - 2.3 8.7 30.3 0.053 13.8 1.8 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type UPF0184 PF03670.8 KFO99038.1 - 2.2e-24 85.3 3.3 2.5e-24 85.2 2.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) EzrA PF06160.7 KFO99038.1 - 0.026 12.7 1.4 0.026 12.7 0.9 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA RasGAP_C PF03836.10 KFO99038.1 - 0.029 14.0 0.9 0.031 13.9 0.6 1.1 1 0 0 1 1 1 0 RasGAP C-terminus DUF948 PF06103.6 KFO99038.1 - 0.047 13.5 0.3 0.055 13.3 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 KFO99038.1 - 0.083 12.4 4.6 0.09 12.3 3.2 1.1 1 0 0 1 1 1 0 IncA protein GST_C_3 PF14497.1 KFO99039.1 - 5.5e-17 62.0 0.3 9.4e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFO99039.1 - 2.6e-14 53.1 0.5 2.4e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KFO99039.1 - 4.3e-11 42.6 0.1 9.8e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.1 KFO99039.1 - 6.9e-09 35.5 0.0 2.2e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFO99039.1 - 7.6e-06 25.7 0.0 7.6e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFO99039.1 - 1.1e-05 25.3 0.2 2.2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF825 PF05695.7 KFO99039.1 - 0.0021 15.5 0.1 0.0027 15.2 0.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF825) GST_N PF02798.15 KFO99039.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 KFO99039.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 ArsC family AAA_13 PF13166.1 KFO99040.1 - 0.00068 18.2 26.1 0.00068 18.2 18.1 4.9 1 1 4 5 5 5 2 AAA domain ADIP PF11559.3 KFO99040.1 - 0.004 17.0 8.9 0.004 17.0 6.2 10.0 2 2 7 10 10 10 4 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 KFO99040.1 - 0.0061 16.3 9.2 0.0061 16.3 6.4 9.0 1 1 7 9 9 9 2 Plant protein of unknown function (DUF641) DUF619 PF04768.8 KFO99040.1 - 0.62 9.4 12.5 2.1 7.7 0.5 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF619) ACT_5 PF13710.1 KFO99040.1 - 3.4 7.5 15.3 4.2 7.2 0.2 5.5 5 1 1 6 6 6 0 ACT domain EFG_II PF14492.1 KFO99040.1 - 6.5 6.6 12.0 15 5.5 0.6 4.4 3 0 0 3 3 3 0 Elongation Factor G, domain II GLE1 PF07817.8 KFO99041.1 - 7.7e-88 293.7 0.0 7.7e-88 293.7 0.0 3.2 3 0 0 3 3 3 1 GLE1-like protein NAP PF00956.13 KFO99042.1 - 2.4e-59 200.4 7.7 2.4e-59 200.4 5.4 2.2 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.7 KFO99042.1 - 0.00077 19.0 1.4 0.0016 17.9 1.0 1.6 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF904 PF06005.7 KFO99042.1 - 0.0064 16.7 2.1 0.014 15.6 1.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Mst1_SARAH PF11629.3 KFO99042.1 - 0.016 15.0 0.8 0.042 13.6 0.5 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 ACCA PF03255.9 KFO99042.1 - 0.12 11.9 0.7 0.22 11.0 0.5 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pkinase PF00069.20 KFO99043.1 - 2.1e-64 217.2 0.0 4.5e-64 216.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain HR1 PF02185.11 KFO99043.1 - 1.5e-45 152.7 28.4 1.7e-17 62.9 2.7 3.4 3 0 0 3 3 3 3 Hr1 repeat Pkinase_Tyr PF07714.12 KFO99043.1 - 5.8e-35 120.6 0.0 1e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFO99043.1 - 2.2e-08 34.4 0.5 5.2e-08 33.2 0.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Uds1 PF15456.1 KFO99043.1 - 1.3e-06 28.3 18.5 0.00096 19.1 0.5 3.3 3 0 0 3 3 3 3 Up-regulated During Septation Kinase-like PF14531.1 KFO99043.1 - 5.7e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF3416 PF11896.3 KFO99043.1 - 0.53 10.2 9.9 0.18 11.7 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3416) zf-DHHC PF01529.15 KFO99044.1 - 3.2e-38 130.8 4.8 4e-38 130.5 3.3 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Baculo_11_kDa PF06143.6 KFO99044.1 - 0.033 13.5 1.6 0.27 10.5 0.7 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family Pico_P2B PF01552.12 KFO99044.1 - 0.088 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Picornavirus 2B protein Arm PF00514.18 KFO99045.1 - 9e-09 34.8 4.7 0.084 12.7 0.0 7.0 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat LRR_4 PF12799.2 KFO99045.1 - 0.00016 21.2 6.2 0.04 13.5 0.1 5.3 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO99045.1 - 0.0025 17.5 10.6 0.34 10.7 0.1 4.4 3 1 0 3 3 3 2 Leucine rich repeat HEAT_EZ PF13513.1 KFO99045.1 - 0.051 14.0 0.4 0.83 10.2 0.0 3.3 5 1 0 5 5 5 0 HEAT-like repeat RabGAP-TBC PF00566.13 KFO99046.1 - 6.2e-38 130.4 7.5 5.5e-35 120.7 1.4 2.7 2 1 0 2 2 2 2 Rab-GTPase-TBC domain TFIID_20kDa PF03847.8 KFO99046.1 - 0.027 14.7 0.6 0.069 13.4 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A PhyH PF05721.8 KFO99047.1 - 3.3e-63 213.5 0.0 4.1e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) BAR PF03114.13 KFO99049.1 - 4.9e-61 206.1 2.3 6.3e-61 205.8 1.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFO99049.1 - 1.5e-10 40.4 0.0 3.2e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFO99049.1 - 1.5e-06 27.4 0.0 2.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFO99049.1 - 6.2e-06 25.6 0.0 1.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 KFO99049.1 - 7.1e-06 25.1 0.4 1.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Kinesin-relat_1 PF12711.2 KFO99049.1 - 0.12 12.8 1.0 0.23 11.8 0.3 1.8 2 0 0 2 2 2 0 Kinesin motor DUF2217 PF10265.4 KFO99050.1 - 5.3e-179 596.2 1.7 2.5e-133 445.6 0.1 2.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2217) 7TM_GPCR_Sri PF10327.4 KFO99050.1 - 0.11 11.4 0.1 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri PAP2 PF01569.16 KFO99051.1 - 5.8e-19 68.0 5.6 1.1e-18 67.1 3.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF3816 PF12822.2 KFO99051.1 - 3.4 7.5 9.4 36 4.1 6.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Carn_acyltransf PF00755.15 KFO99052.1 - 2.8e-232 772.0 0.0 3.2e-232 771.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PTPA PF03095.10 KFO99053.1 - 1.7e-115 385.3 0.0 1.9e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltransf_PK PF05891.7 KFO99054.1 - 1.1e-92 309.3 0.0 1.2e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 KFO99054.1 - 9.9e-10 38.7 0.0 1.8e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO99054.1 - 6.1e-09 36.2 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO99054.1 - 1.9e-08 34.8 0.0 2.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO99054.1 - 1.5e-06 28.4 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFO99054.1 - 4.5e-05 22.7 0.1 6.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KFO99054.1 - 6e-05 22.6 0.0 8.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO99054.1 - 9e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFO99054.1 - 9.3e-05 21.6 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFO99054.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFO99054.1 - 0.028 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Dioxygenase_N PF04444.9 KFO99054.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus DREV PF05219.7 KFO99054.1 - 0.077 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Ank_2 PF12796.2 KFO99055.1 - 1.6e-26 92.4 0.0 3.4e-11 43.3 0.0 3.8 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFO99055.1 - 1.3e-23 81.5 0.6 2.8e-10 39.4 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 KFO99055.1 - 2.4e-23 82.0 0.6 1.1e-05 25.7 0.0 6.4 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO99055.1 - 1.3e-17 63.3 1.9 4.1e-09 36.3 0.0 5.1 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO99055.1 - 5.2e-15 54.0 1.1 1.9e-06 27.5 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat SOCS_box PF07525.11 KFO99055.1 - 2.7e-13 49.5 0.9 9.4e-13 47.7 0.6 2.0 1 0 0 1 1 1 1 SOCS box Homeobox PF00046.24 KFO99056.1 - 1.7e-23 81.9 6.6 3.5e-23 80.9 4.6 1.5 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFO99056.1 - 8.7e-09 34.5 0.0 2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFO99056.1 - 0.00043 19.9 0.3 0.001 18.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain MAPEG PF01124.13 KFO99057.1 - 1.6e-22 79.4 0.4 1.9e-22 79.2 0.3 1.0 1 0 0 1 1 1 1 MAPEG family Acyl_transf_3 PF01757.17 KFO99057.1 - 0.014 14.2 2.3 0.015 14.1 1.6 1.2 1 1 0 1 1 1 0 Acyltransferase family Torsin PF06309.6 KFO99058.1 - 2.4e-43 147.0 0.1 4.6e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA PF00004.24 KFO99058.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KFO99058.1 - 0.0024 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KFO99058.1 - 0.0026 17.9 0.0 0.036 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KFO99058.1 - 0.0035 16.9 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KFO99059.1 - 4.2e-53 178.5 0.5 7.4e-53 177.7 0.4 1.4 1 0 0 1 1 1 1 Torsin AAA PF00004.24 KFO99059.1 - 0.0053 16.9 0.0 0.0091 16.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KFO99059.1 - 0.018 14.4 0.2 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 KFO99059.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFO99059.1 - 0.07 13.2 0.1 14 5.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.9 KFO99059.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Hep_59 PF07052.6 KFO99060.1 - 4.2e-30 104.1 4.7 1.3e-29 102.6 3.3 1.8 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 UCH PF00443.24 KFO99061.1 - 5.8e-65 219.0 0.0 5.7e-64 215.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO99061.1 - 5e-25 88.5 0.0 5.1e-24 85.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFO99061.1 - 1.7e-24 86.0 1.0 9e-15 54.8 0.0 2.7 2 0 0 2 2 2 2 DUSP domain zf-UBP PF02148.14 KFO99061.1 - 4.3e-16 58.7 4.9 4.3e-16 58.7 3.4 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein FCH PF00611.18 KFO99062.1 - 4.6e-21 74.8 3.5 4.6e-21 74.8 2.4 3.6 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFO99062.1 - 1.2e-10 40.7 0.1 2.5e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFO99062.1 - 2.6e-10 39.4 0.1 5.9e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFO99062.1 - 1.8e-06 27.3 0.1 4.1e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.11 KFO99062.1 - 1.4e-05 24.7 1.8 1.4e-05 24.7 1.2 3.6 4 1 0 4 4 4 1 Hr1 repeat SH3_3 PF08239.6 KFO99062.1 - 3.1e-05 24.0 0.3 7.2e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Lzipper-MIP1 PF14389.1 KFO99062.1 - 0.0008 19.4 1.2 0.0028 17.7 0.8 1.9 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Uds1 PF15456.1 KFO99062.1 - 0.0015 18.5 0.2 0.0015 18.5 0.2 3.9 2 1 1 3 3 2 1 Up-regulated During Septation PG_binding_4 PF12229.3 KFO99062.1 - 0.01 16.0 0.2 0.037 14.2 0.1 2.0 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Laminin_II PF06009.7 KFO99062.1 - 0.015 15.0 7.3 0.22 11.2 0.3 3.0 2 1 0 2 2 2 0 Laminin Domain II Spectrin PF00435.16 KFO99062.1 - 0.33 11.2 21.9 0.16 12.2 1.8 4.1 2 1 1 3 3 3 0 Spectrin repeat zf-C4H2 PF10146.4 KFO99062.1 - 7.2 6.5 17.5 1 9.3 2.9 3.1 1 1 1 2 2 2 0 Zinc finger-containing protein Lung_7-TM_R PF06814.8 KFO99063.1 - 1.1e-94 316.7 8.0 1.3e-94 316.4 5.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor EF-hand_7 PF13499.1 KFO99064.1 - 6.7e-24 83.8 0.8 1.1e-15 57.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFO99064.1 - 6.7e-23 78.2 5.9 4.1e-07 28.8 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFO99064.1 - 7.4e-22 75.2 2.9 1.5e-05 24.4 0.0 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KFO99064.1 - 4.7e-16 57.3 4.7 6.1e-05 22.1 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KFO99064.1 - 1.7e-15 56.3 4.3 9.6e-05 21.9 0.2 3.7 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFO99064.1 - 3.3e-05 23.8 0.4 0.0078 16.2 0.1 2.9 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFO99064.1 - 0.00058 19.5 1.8 0.49 10.1 0.0 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand S10_plectin PF03501.10 KFO99064.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_9 PF14658.1 KFO99064.1 - 0.014 15.2 0.0 0.44 10.5 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain EF-hand_3 PF09069.6 KFO99064.1 - 0.015 15.3 0.0 0.058 13.4 0.0 1.8 2 0 0 2 2 2 0 EF-hand G2F PF07474.7 KFO99065.1 - 3.7e-29 101.4 0.0 5.2e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 G2F domain I-set PF07679.11 KFO99065.1 - 3.2e-16 58.9 0.0 1.1e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99065.1 - 1.4e-12 47.5 0.0 4.4e-10 39.5 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFO99065.1 - 1.6e-08 34.9 0.0 1.2e-06 28.8 0.0 2.9 2 0 0 2 2 2 1 Immunoglobulin domain EGF_CA PF07645.10 KFO99065.1 - 3.3e-08 33.3 2.9 3.3e-08 33.3 2.0 2.2 3 0 0 3 3 2 1 Calcium-binding EGF domain cEGF PF12662.2 KFO99065.1 - 2.2e-07 30.3 1.7 0.0015 18.1 0.6 2.6 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF PF00008.22 KFO99065.1 - 9.7e-05 22.2 9.6 9.7e-05 22.2 6.7 2.3 2 0 0 2 2 2 1 EGF-like domain V-set PF07686.12 KFO99065.1 - 0.001 18.9 0.0 0.065 13.1 0.0 3.1 2 1 0 2 2 2 1 Immunoglobulin V-set domain FXa_inhibition PF14670.1 KFO99065.1 - 0.0015 18.6 7.9 0.0015 18.6 5.5 2.3 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site ig PF00047.20 KFO99065.1 - 0.0016 18.5 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain EGF_3 PF12947.2 KFO99065.1 - 0.057 13.3 3.8 0.15 12.0 2.6 1.8 1 0 0 1 1 1 0 EGF domain hEGF PF12661.2 KFO99065.1 - 0.2 11.8 5.1 0.58 10.3 1.5 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF Arginosuc_synth PF00764.14 KFO99066.1 - 2e-152 507.7 0.0 4.3e-152 506.6 0.0 1.5 1 1 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KFO99066.1 - 0.0001 21.6 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KFO99066.1 - 0.00086 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KFO99066.1 - 0.0028 16.2 0.0 0.0048 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase KH_1 PF00013.24 KFO99067.1 - 5.4e-67 221.3 15.7 3e-19 68.3 0.1 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 KFO99067.1 - 7.6e-42 140.3 24.7 1.8e-11 43.4 0.5 4.8 5 0 0 5 5 5 4 KH domain KH_2 PF07650.12 KFO99067.1 - 3.6e-22 77.7 9.5 2.1e-05 24.0 0.2 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 KFO99067.1 - 4.7e-12 45.3 7.0 0.02 14.5 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_5 PF13184.1 KFO99067.1 - 7.2e-05 22.5 6.6 4.3 7.2 0.0 4.4 4 0 0 4 4 4 3 NusA-like KH domain DUF1897 PF09005.5 KFO99067.1 - 0.00039 19.8 11.6 0.00085 18.7 8.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) SET PF00856.23 KFO99068.1 - 0.017 15.3 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 SET domain Tissue_fac PF01108.12 KFO99068.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Tissue factor zf-H2C2_2 PF13465.1 KFO99069.1 - 3.4e-13 49.1 6.4 7.9e-07 29.0 0.5 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO99069.1 - 3.6e-06 26.9 3.0 3.6e-06 26.9 2.1 2.2 3 0 0 3 3 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFO99069.1 - 0.00044 20.2 0.1 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFO99069.1 - 0.00045 20.3 2.8 0.00045 20.3 1.9 1.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 KFO99069.1 - 0.0024 18.0 0.7 0.0024 18.0 0.5 1.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFO99069.1 - 0.017 15.2 0.1 0.017 15.1 0.1 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFO99069.1 - 0.04 13.8 0.6 0.066 13.1 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.10 KFO99069.1 - 0.047 13.4 0.8 0.059 13.1 0.6 1.3 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 KFO99069.1 - 0.052 13.8 0.8 0.052 13.8 0.5 2.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 KFO99069.1 - 0.1 12.3 2.9 0.18 11.5 2.0 1.5 1 1 0 1 1 1 0 zinc-finger of a C2HC-type Elf1 PF05129.8 KFO99069.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.7 KFO99069.1 - 0.12 12.5 0.4 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Pkinase_Tyr PF07714.12 KFO99070.1 - 2.4e-99 331.6 0.0 3.4e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO99070.1 - 3.3e-51 173.9 0.0 6e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain F_actin_bind PF08919.5 KFO99070.1 - 4.2e-30 103.7 0.1 8.9e-30 102.6 0.1 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.19 KFO99070.1 - 1e-23 82.8 0.2 2.6e-23 81.6 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFO99070.1 - 1.6e-12 46.6 0.0 2.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFO99070.1 - 1.4e-10 40.5 0.0 2.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO99070.1 - 4.1e-08 32.6 0.0 8.1e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFO99070.1 - 3.2e-05 24.0 0.2 8.6e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Kinase-like PF14531.1 KFO99070.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SH3_6 PF12913.2 KFO99070.1 - 0.076 12.2 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type SH3_4 PF06347.8 KFO99070.1 - 0.12 11.9 0.2 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Fibrinogen_C PF00147.13 KFO99071.1 - 4.9e-74 248.8 4.4 6.7e-74 248.4 3.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Transposase_22 PF02994.9 KFO99071.1 - 0.025 13.0 0.1 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 L1 transposable element CENP-F_leu_zip PF10473.4 KFO99071.1 - 0.078 12.8 0.7 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 KFO99071.1 - 0.34 11.2 4.0 0.4 11.0 0.3 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Laminin_N PF00055.12 KFO99072.1 - 5.8e-81 270.9 0.9 9.9e-81 270.1 0.0 2.0 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFO99072.1 - 8.8e-81 265.6 221.3 7.6e-12 44.9 11.0 12.1 12 0 0 12 12 12 11 Laminin EGF-like (Domains III and V) Laminin_B PF00052.13 KFO99072.1 - 1.8e-12 47.0 0.0 4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Laminin B (Domain IV) F5_F8_type_C PF00754.20 KFO99072.1 - 0.032 14.0 0.1 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 F5/8 type C domain EF-hand_1 PF00036.27 KFO99073.1 - 0.0023 17.0 3.3 0.091 12.1 0.4 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFO99073.1 - 0.0046 17.0 0.1 0.0074 16.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFO99073.1 - 0.0051 16.5 0.0 0.068 13.0 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFO99073.1 - 0.043 13.4 0.6 0.95 9.1 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain pair WD40 PF00400.27 KFO99074.1 - 1.4e-05 24.7 0.1 0.017 14.9 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF4613 PF15390.1 KFO99074.1 - 0.0032 15.7 0.1 0.0043 15.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) RFC1 PF08519.7 KFO99076.1 - 0.15 11.8 0.5 0.25 11.1 0.3 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain PAP2 PF01569.16 KFO99077.1 - 1.1e-15 57.4 3.3 1.8e-15 56.7 2.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KFO99077.1 - 0.043 14.0 0.5 0.097 12.9 0.3 1.5 1 0 0 1 1 1 0 PAP2 superfamily C-terminal YscJ_FliF_C PF08345.6 KFO99077.1 - 0.17 11.8 1.0 0.24 11.3 0.7 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Myosin_tail_1 PF01576.14 KFO99078.1 - 0 1092.4 287.1 0 1077.2 151.7 3.1 2 1 0 2 2 2 2 Myosin tail Myosin_head PF00063.16 KFO99078.1 - 1.1e-273 909.5 2.9 1.1e-273 909.5 2.0 3.2 4 1 1 5 5 5 1 Myosin head (motor domain) Filament PF00038.16 KFO99078.1 - 9.1e-05 22.0 235.8 0.00034 20.1 10.2 9.1 1 1 5 6 6 6 3 Intermediate filament protein DUF1664 PF07889.7 KFO99078.1 - 0.006 16.3 4.6 0.006 16.3 3.2 12.8 1 1 10 14 14 14 5 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KFO99078.1 - 0.013 14.7 79.0 0.023 13.8 2.8 9.4 1 1 7 10 10 10 0 Reovirus sigma C capsid protein IQ PF00612.22 KFO99078.1 - 0.032 13.8 3.8 0.098 12.3 0.8 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_19 PF13245.1 KFO99078.1 - 0.12 12.1 0.0 0.46 10.2 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Pentapeptide PF00805.17 KFO99079.1 - 0.042 13.0 0.5 0.071 12.3 0.4 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) DUF1072 PF06380.6 KFO99079.1 - 0.45 10.2 3.4 0.78 9.4 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) MORN PF02493.15 KFO99081.1 - 5.1e-11 41.6 12.7 5.8e-06 25.7 1.8 3.7 4 0 0 4 4 4 3 MORN repeat Fibrinogen_C PF00147.13 KFO99082.1 - 3.3e-71 239.6 9.5 3.9e-71 239.3 6.6 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Collagen PF01391.13 KFO99082.1 - 1.5e-09 37.2 24.1 2.8e-09 36.3 16.7 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_S28 PF05577.7 KFO99083.1 - 8.1e-81 271.7 0.0 9.4e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.15 KFO99083.1 - 4.3e-07 29.7 1.6 1.1e-06 28.4 1.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFO99083.1 - 1.4e-06 28.4 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFO99083.1 - 3.5e-06 26.8 0.0 6.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.6 KFO99083.1 - 0.0018 16.7 0.0 0.0029 16.1 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.16 KFO99083.1 - 0.0029 16.8 0.1 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.3 KFO99083.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Glyco_hydro_47 PF01532.15 KFO99084.1 - 4.4e-175 582.6 0.0 5.2e-175 582.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UDPGP PF01704.13 KFO99085.1 - 7.3e-76 255.3 0.0 9.9e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KFO99085.1 - 0.00062 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain GDA1_CD39 PF01150.12 KFO99086.1 - 3.4e-66 223.5 0.0 3.8e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TMEM141 PF15110.1 KFO99087.1 - 2.8e-18 65.9 0.0 3.7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 TMEM141 protein family GST_C_2 PF13410.1 KFO99088.1 - 3.5e-07 30.0 0.0 5.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFO99088.1 - 0.00068 20.0 0.0 0.00091 19.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFO99088.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC2_membrane_3 PF12698.2 KFO99089.1 - 5e-59 200.0 36.2 1.5e-38 132.7 10.7 3.5 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 KFO99089.1 - 8.2e-58 194.5 0.0 1.3e-29 103.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFO99089.1 - 1.6e-21 77.5 0.4 3.9e-08 33.6 0.1 4.4 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KFO99089.1 - 0.00051 19.1 0.0 1.5 7.7 0.1 3.2 4 0 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.1 KFO99089.1 - 0.00055 20.3 1.2 0.21 11.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KFO99089.1 - 0.0033 17.3 0.0 2.6 8.0 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 KFO99089.1 - 0.031 13.7 3.3 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 KFO99089.1 - 0.066 12.7 3.9 0.71 9.4 0.2 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain DUF258 PF03193.11 KFO99089.1 - 0.12 11.6 0.3 1.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KFO99089.1 - 0.12 11.5 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Glyco_transf_10 PF00852.14 KFO99090.1 - 8.6e-112 373.1 2.9 1e-111 372.9 2.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Pou PF00157.12 KFO99091.1 - 1.2e-32 111.4 0.1 2.7e-32 110.2 0.1 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFO99091.1 - 9.2e-19 66.8 0.3 1.7e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO99091.1 - 0.0035 16.9 0.1 0.0083 15.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_19 PF12844.2 KFO99091.1 - 0.05 13.6 0.0 4.4 7.4 0.0 2.5 1 1 0 1 1 1 0 Helix-turn-helix domain NPDC1 PF06809.6 KFO99092.1 - 5.8e-81 271.9 7.3 1.2e-80 270.9 5.1 1.5 1 1 0 1 1 1 1 Neural proliferation differentiation control-1 protein (NPDC1) Lipocalin PF00061.18 KFO99093.1 - 0.0029 17.6 0.0 0.0031 17.5 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFO99094.1 - 7.3e-27 94.1 0.0 8.8e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFO99095.1 - 3.4e-22 78.9 0.0 4.1e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family WD40 PF00400.27 KFO99096.1 - 9.8e-11 41.1 2.8 1e-10 41.0 0.4 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat MATH PF00917.21 KFO99097.1 - 1.7e-25 89.5 0.0 2.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 MATH domain zf-TRAF PF02176.13 KFO99097.1 - 6.9e-07 29.5 0.5 6.9e-07 29.5 0.3 2.5 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4 PF00097.20 KFO99097.1 - 1.1e-05 24.9 9.0 4.3e-05 23.0 6.2 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO99097.1 - 0.00015 21.7 9.4 0.00057 19.8 6.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFO99097.1 - 0.00017 21.3 5.0 0.001 18.9 3.5 2.4 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFO99097.1 - 0.00062 19.4 3.1 0.00062 19.4 2.2 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KFO99097.1 - 0.0084 15.8 8.8 0.024 14.3 6.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFO99097.1 - 0.031 13.9 6.5 0.088 12.4 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Reo_sigmaC PF04582.7 KFO99097.1 - 0.048 12.8 0.1 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein zf-RING_2 PF13639.1 KFO99097.1 - 0.066 13.0 6.5 0.27 11.0 4.5 2.2 1 0 0 1 1 1 0 Ring finger domain SlyX PF04102.7 KFO99097.1 - 0.26 11.6 1.2 1.9 8.8 0.3 2.2 1 1 1 2 2 2 0 SlyX zf-RING_4 PF14570.1 KFO99097.1 - 5.1 6.7 11.4 5.1 6.7 5.9 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain LIM PF00412.17 KFO99098.1 - 1.6e-33 114.5 28.1 1.3e-16 60.4 6.1 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFO99098.1 - 6.9e-18 64.0 2.3 1.5e-17 62.9 1.6 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO99098.1 - 0.00012 21.6 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF2464 PF10240.4 KFO99099.1 - 3.1e-89 298.6 0.0 3.6e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2464) SIN1 PF05422.7 KFO99100.1 - 3.9e-172 573.4 1.9 4.8e-172 573.1 1.3 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) RasGAP PF00616.14 KFO99101.1 - 1.1e-35 123.0 0.1 3.1e-35 121.6 0.1 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.13 KFO99101.1 - 6.4e-29 100.0 0.0 1.8e-28 98.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HSP70 PF00012.15 KFO99102.1 - 4.7e-267 886.7 10.3 5.3e-267 886.6 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFO99102.1 - 2.7e-17 62.3 0.1 6.6e-17 61.0 0.1 1.6 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 KFO99102.1 - 3.2e-05 23.1 1.2 0.0013 17.8 0.1 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 KFO99102.1 - 0.0096 14.7 1.1 0.12 11.1 0.5 2.3 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 KFO99102.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Kelch_3 PF13415.1 KFO99103.1 - 1.5e-28 98.2 7.9 3.6e-09 36.5 0.0 5.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KFO99103.1 - 5.5e-24 83.2 1.4 8.7e-08 32.0 0.0 3.6 2 1 2 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KFO99103.1 - 7.7e-24 82.9 0.0 2.7e-09 36.3 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 KFO99103.1 - 1.5e-22 79.0 3.0 9.5e-06 25.4 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 KFO99103.1 - 8e-20 70.3 12.6 1.7e-07 30.8 0.1 5.4 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFO99103.1 - 2e-14 52.7 2.8 4.7e-06 26.1 0.0 4.4 4 1 0 4 4 4 3 Kelch motif Metallophos PF00149.23 KFO99104.1 - 1.6e-42 145.2 0.3 1.9e-42 144.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase P16-Arc PF04699.9 KFO99105.1 - 1.7e-38 132.0 0.0 1.8e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 KFO99105.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family TPX2_importin PF12214.3 KFO99105.1 - 0.035 14.1 0.0 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein GRIP PF01465.15 KFO99106.1 - 7.7e-15 54.1 0.9 2.7e-14 52.4 0.6 2.1 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 KFO99106.1 - 0.0064 15.7 7.3 0.0064 15.7 5.0 5.1 2 1 3 5 5 5 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KFO99106.1 - 0.35 8.5 149.3 3 5.4 21.7 3.4 1 1 0 2 2 2 0 Myosin tail DUF869 PF05911.6 KFO99106.1 - 2.5 6.2 118.5 0.01 14.1 39.3 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF3550 PF12070.3 KFO99107.1 - 2.9e-241 801.6 4.6 4.7e-241 800.9 3.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3550/UPF0682) Ribosomal_L29 PF00831.18 KFO99108.1 - 0.00036 20.1 0.9 0.00036 20.1 0.6 2.5 2 1 0 2 2 2 1 Ribosomal L29 protein XFP_N PF09364.5 KFO99108.1 - 0.033 12.7 0.0 0.033 12.7 0.0 1.0 1 0 0 1 1 1 0 XFP N-terminal domain OmpH PF03938.9 KFO99108.1 - 0.087 12.7 2.7 0.092 12.6 1.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HTH_12 PF08461.5 KFO99108.1 - 0.37 10.5 2.8 0.3 10.8 1.1 1.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Hormone_recep PF00104.25 KFO99109.1 - 6.3e-29 100.5 4.6 1.2e-28 99.5 3.2 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO99109.1 - 3.6e-28 97.6 17.9 7.6e-28 96.5 12.4 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) 7tm_2 PF00002.19 KFO99110.1 - 8.2e-47 159.3 24.5 1.4e-46 158.5 17.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Pentaxin PF00354.12 KFO99110.1 - 3.6e-28 98.3 0.1 7.2e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFO99110.1 - 2.8e-15 56.8 0.1 4.8e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GPS PF01825.16 KFO99110.1 - 3.3e-11 43.1 7.3 8e-11 41.8 0.7 3.1 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain Dicty_CAR PF05462.6 KFO99110.1 - 2.2e-06 26.8 10.4 3.7e-06 26.0 7.2 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor DUF3497 PF12003.3 KFO99110.1 - 0.0014 18.0 0.5 0.0023 17.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) Lectin_C PF00059.16 KFO99110.1 - 0.0029 18.1 1.4 0.58 10.8 0.0 3.1 3 0 0 3 3 3 1 Lectin C-type domain Laminin_G_2 PF02210.19 KFO99110.1 - 0.018 15.1 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain Tex_N PF09371.5 KFO99110.1 - 0.042 13.1 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Pox_P21 PF05313.7 KFO99110.1 - 9.1 5.4 11.1 0.1 11.8 2.0 1.9 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Proteasome PF00227.21 KFO99111.1 - 1.6e-50 171.0 0.2 2e-50 170.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KFO99111.1 - 4.1e-15 54.7 0.9 1.2e-14 53.2 0.1 2.2 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Pkinase PF00069.20 KFO99112.1 - 3.5e-48 164.0 0.4 1.5e-47 161.9 0.3 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99112.1 - 1.4e-34 119.3 0.1 2.2e-34 118.7 0.1 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase DENN PF02141.16 KFO99113.1 - 9.5e-48 162.3 2.1 1.9e-47 161.3 1.4 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KFO99113.1 - 1.7e-17 63.1 0.3 3.3e-17 62.2 0.2 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KFO99113.1 - 7.6e-16 57.8 1.5 2.1e-15 56.4 1.0 1.7 1 0 0 1 1 1 1 uDENN domain EGF PF00008.22 KFO99114.1 - 2.7e-82 270.0 195.6 4.6e-10 39.2 5.6 15.2 14 1 0 14 14 14 14 EGF-like domain EGF_CA PF07645.10 KFO99114.1 - 5.5e-29 99.8 204.0 4.9e-05 23.2 5.6 15.4 11 4 4 15 15 15 12 Calcium-binding EGF domain hEGF PF12661.2 KFO99114.1 - 6.1e-11 41.6 144.0 0.00068 19.5 2.4 16.5 15 1 0 15 15 15 8 Human growth factor-like EGF EGF_2 PF07974.8 KFO99114.1 - 2.9e-10 40.1 237.4 0.0035 17.4 6.2 15.4 14 1 1 15 15 15 10 EGF-like domain EGF_3 PF12947.2 KFO99114.1 - 1.9e-09 37.2 177.0 0.082 12.8 3.0 15.1 13 3 1 14 14 14 10 EGF domain FXa_inhibition PF14670.1 KFO99114.1 - 0.00059 19.9 179.2 0.11 12.6 4.9 14.9 5 4 9 14 14 14 8 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFO99114.1 - 0.013 15.1 2.1 0.013 15.1 1.4 17.2 16 2 0 16 16 16 0 Complement Clr-like EGF-like DUF190 PF02641.10 KFO99114.1 - 0.098 12.5 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 DZF PF07528.9 KFO99115.1 - 3.4e-79 265.7 0.0 5.4e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 DZF domain dsrm PF00035.20 KFO99115.1 - 1e-27 96.5 0.0 2.4e-14 53.6 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFO99115.1 - 1.1e-06 28.8 0.3 0.11 12.8 0.0 3.2 3 0 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 RabGAP-TBC PF00566.13 KFO99116.1 - 5.4e-57 192.7 2.2 5.4e-57 192.7 1.5 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF3694 PF12473.3 KFO99116.1 - 2.2e-35 121.3 0.0 6.7e-35 119.7 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein PID PF00640.18 KFO99116.1 - 1.1e-06 28.6 2.3 5.7e-06 26.3 0.0 3.0 3 1 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFO99116.1 - 0.0019 18.1 0.0 0.0066 16.3 0.0 2.0 1 0 0 1 1 1 1 Phosphotyrosine-binding domain BTB PF00651.26 KFO99117.1 - 2.5e-19 69.3 1.1 4.9e-19 68.3 0.2 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.21 KFO99117.1 - 6.4e-18 63.9 39.2 9.5e-06 25.6 1.8 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO99117.1 - 5.3e-17 61.1 23.1 1e-06 28.7 0.3 5.8 4 1 1 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO99117.1 - 1.1e-14 53.5 32.4 0.00027 21.0 0.5 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO99117.1 - 0.0012 18.7 23.6 0.67 9.9 2.5 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO99117.1 - 0.0025 17.8 19.2 0.35 11.0 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO99117.1 - 0.0039 17.3 25.1 0.055 13.6 1.9 4.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type DUF899 PF05988.7 KFO99117.1 - 0.0078 15.6 0.1 0.0078 15.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF899) zf-C2H2_2 PF12756.2 KFO99117.1 - 0.1 12.7 30.4 0.32 11.1 0.7 5.3 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 KFO99117.1 - 0.14 11.5 4.1 1.1 8.7 0.0 3.4 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.6 KFO99117.1 - 0.15 11.6 7.9 13 5.4 0.0 4.3 1 1 3 4 4 4 0 GAGA factor zf-CHCC PF10276.4 KFO99117.1 - 0.16 11.8 0.1 0.16 11.8 0.0 2.9 4 0 0 4 4 4 0 Zinc-finger domain zf-BED PF02892.10 KFO99117.1 - 4.5 7.1 26.9 5 6.9 1.7 4.3 2 2 2 4 4 4 0 BED zinc finger zf-LYAR PF08790.6 KFO99117.1 - 6.9 6.4 9.1 28 4.5 0.1 3.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-CCCH PF00642.19 KFO99118.1 - 1.6e-07 30.8 2.0 1.6e-07 30.8 1.4 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 KFO99118.1 - 4.8e-06 26.1 8.0 1.2e-05 24.8 5.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFO99118.1 - 1.2e-05 25.0 6.8 4e-05 23.3 4.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFO99118.1 - 3.6e-05 23.6 7.6 3.6e-05 23.6 5.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO99118.1 - 7.9e-05 22.2 4.4 7.9e-05 22.2 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFO99118.1 - 0.00035 20.2 6.4 0.00035 20.2 4.4 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFO99118.1 - 0.00065 19.5 6.2 0.00065 19.5 4.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFO99118.1 - 0.0022 17.5 8.4 0.0058 16.2 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Citrate_synt PF00285.16 KFO99118.1 - 0.0041 15.8 0.0 0.0069 15.1 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase Xin PF08043.7 KFO99118.1 - 0.0082 15.7 0.0 0.023 14.3 0.0 1.8 1 0 0 1 1 1 1 Xin repeat Prok-RING_4 PF14447.1 KFO99118.1 - 0.2 11.1 8.7 0.07 12.6 0.9 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFO99118.1 - 1.1 8.8 5.6 2.4 7.8 3.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Phosducin PF02114.11 KFO99119.1 - 5e-32 110.6 3.2 5.3e-32 110.5 2.2 1.0 1 0 0 1 1 1 1 Phosducin Ded_cyto PF06920.8 KFO99119.1 - 0.011 15.0 0.2 0.013 14.7 0.2 1.1 1 0 0 1 1 1 0 Dedicator of cytokinesis CCDC66 PF15236.1 KFO99119.1 - 0.018 14.6 10.3 0.021 14.4 7.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF148 PF02520.12 KFO99119.1 - 0.038 13.7 0.4 0.052 13.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 TMEM247 PF15444.1 KFO99119.1 - 0.12 12.1 0.8 0.13 12.0 0.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 247 OmpH PF03938.9 KFO99119.1 - 0.37 10.7 5.8 0.46 10.4 4.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PBP_sp32 PF07222.7 KFO99119.1 - 4.4 6.4 6.3 5.4 6.1 4.3 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 An_peroxidase PF03098.10 KFO99120.1 - 1.6e-94 317.1 0.0 6.5e-92 308.5 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase EGF PF00008.22 KFO99120.1 - 0.0062 16.4 11.3 0.014 15.3 7.8 1.6 1 0 0 1 1 1 1 EGF-like domain RRF PF01765.14 KFO99121.1 - 1.7e-42 144.7 4.0 2.7e-42 144.0 2.7 1.3 1 0 0 1 1 1 1 Ribosome recycling factor DUF883 PF05957.8 KFO99121.1 - 0.65 10.4 8.7 0.17 12.3 2.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RRM_5 PF13893.1 KFO99122.1 - 6.7e-13 48.2 0.1 9.5e-13 47.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFO99122.1 - 7.3e-12 44.7 0.1 1.2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO99122.1 - 8.4e-09 35.2 0.1 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3446 PF11928.3 KFO99122.1 - 0.17 12.0 1.2 0.26 11.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) LIM PF00412.17 KFO99123.1 - 3.1e-29 100.8 18.2 1.8e-15 56.7 2.1 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFO99123.1 - 5.7e-17 61.0 0.7 9.5e-17 60.3 0.5 1.4 1 0 0 1 1 1 1 Homeobox domain MRP-L20 PF12824.2 KFO99123.1 - 0.015 15.3 0.2 0.015 15.3 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 TF_Zn_Ribbon PF08271.7 KFO99123.1 - 0.32 10.3 0.1 0.32 10.3 0.0 2.6 3 0 0 3 3 3 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.5 KFO99123.1 - 1.2 9.3 11.9 3.2 7.9 0.5 3.4 3 0 0 3 3 3 0 Archaeal TRASH domain zinc_ribbon_2 PF13240.1 KFO99123.1 - 1.6 8.3 8.1 19 4.9 0.1 4.0 3 1 1 4 4 4 0 zinc-ribbon domain YhfH PF14149.1 KFO99123.1 - 5.5 6.8 11.6 7.5 6.4 0.2 3.6 4 0 0 4 4 4 0 YhfH-like protein HypA PF01155.14 KFO99123.1 - 5.6 6.6 9.0 2.1 8.0 0.4 2.8 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family MORN PF02493.15 KFO99124.1 - 0.0089 15.7 2.0 0.027 14.1 0.0 2.4 2 0 0 2 2 2 1 MORN repeat CHCH PF06747.8 KFO99125.1 - 1.3e-08 34.5 1.1 2.2e-08 33.7 0.8 1.4 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.12 KFO99125.1 - 0.052 13.5 1.0 0.077 13.0 0.7 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 KFO99125.1 - 0.12 12.1 2.3 0.19 11.5 1.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 KFO99125.1 - 0.15 12.0 1.1 0.84 9.6 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein TTL PF03133.10 KFO99127.1 - 2.2e-67 227.0 0.0 3.4e-67 226.4 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFO99127.1 - 0.00073 18.4 0.0 0.034 12.9 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 KFO99127.1 - 0.0069 16.2 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KFO99127.1 - 0.008 15.6 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Band_7 PF01145.20 KFO99128.1 - 5.1e-37 127.5 0.5 6.2e-37 127.2 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFO99128.1 - 0.0044 16.5 0.1 0.0071 15.8 0.1 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Gelsolin PF00626.17 KFO99129.1 - 1.3e-109 357.9 0.4 7.1e-21 73.6 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat chaperone_DMP PF10448.4 KFO99129.1 - 0.066 13.1 0.0 0.24 11.3 0.0 1.9 1 1 1 2 2 2 0 20S proteasome chaperone CutA1 PF03091.10 KFO99129.1 - 0.2 11.3 0.5 3.4 7.3 0.0 2.8 4 0 0 4 4 4 0 CutA1 divalent ion tolerance protein Ras PF00071.17 KFO99130.1 - 6.7e-61 204.4 0.1 7.8e-61 204.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO99130.1 - 2.1e-19 70.1 0.0 3.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO99130.1 - 1.4e-12 47.2 0.0 1.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFO99130.1 - 5.2e-06 26.0 0.0 0.00012 21.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFO99130.1 - 6.6e-06 26.0 0.0 8.4e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFO99130.1 - 0.00015 21.0 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFO99130.1 - 0.0029 17.1 0.0 0.093 12.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KFO99130.1 - 0.024 14.7 0.1 0.056 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFO99130.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.5 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.5 KFO99130.1 - 0.046 12.9 0.0 0.066 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 KFO99130.1 - 0.071 13.3 0.0 0.38 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 KFO99130.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1863 PF08937.6 KFO99130.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) LRR_4 PF12799.2 KFO99131.1 - 1.5e-20 72.3 26.7 1.3e-08 34.2 0.3 6.7 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO99131.1 - 6e-18 64.3 29.7 4e-11 42.5 2.9 4.8 3 1 2 5 5 5 3 Leucine rich repeat LRR_9 PF14580.1 KFO99131.1 - 6.3e-15 55.1 2.5 6.3e-15 55.1 1.7 2.8 2 1 1 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.28 KFO99131.1 - 1.2e-08 33.8 16.5 0.051 13.6 0.0 6.6 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 KFO99131.1 - 5.5e-05 22.8 15.6 0.031 14.3 0.2 6.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 KFO99131.1 - 0.001 18.8 15.8 0.88 10.0 0.0 7.3 7 0 0 7 7 7 3 Leucine rich repeat A2M_comp PF07678.9 KFO99132.1 - 6.1e-67 225.4 0.8 9.1e-67 224.8 0.5 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 KFO99132.1 - 3.7e-26 90.5 1.3 1.1e-25 88.9 0.1 2.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 KFO99132.1 - 3.8e-24 85.0 0.1 3.2e-23 82.0 0.0 2.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin family N-terminal region A2M_recep PF07677.9 KFO99132.1 - 7.1e-24 83.8 0.0 2.6e-23 82.0 0.0 2.1 1 0 0 1 1 1 1 A-macroglobulin receptor NTR PF01759.16 KFO99132.1 - 2.4e-22 78.5 0.1 9.7e-22 76.6 0.0 2.1 1 0 0 1 1 1 1 UNC-6/NTR/C345C module A2M_N PF01835.14 KFO99132.1 - 1.5e-16 60.4 0.1 1.1e-15 57.7 0.0 2.5 3 0 0 3 3 3 1 MG2 domain Prenyltrans_2 PF13249.1 KFO99132.1 - 1.8e-08 34.7 0.5 0.00068 20.0 0.0 2.6 2 0 0 2 2 2 2 Prenyltransferase-like ANATO PF01821.13 KFO99132.1 - 8.6e-08 32.1 8.0 2.4e-07 30.7 5.5 1.8 1 0 0 1 1 1 1 Anaphylotoxin-like domain Prenyltrans PF00432.16 KFO99132.1 - 0.0042 16.6 0.2 0.57 9.8 0.0 2.8 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat Thiol-ester_cl PF10569.4 KFO99132.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region BAT2_N PF07001.6 KFO99133.1 - 1.9e-79 266.4 9.8 1.9e-79 266.4 6.8 5.3 4 2 2 6 6 6 1 BAT2 N-terminus PMT PF02366.13 KFO99134.1 - 1.1e-86 290.1 25.2 1.1e-86 290.1 17.4 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFO99134.1 - 9.6e-13 48.0 0.3 1.9e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 MIR domain PRK PF00485.13 KFO99135.1 - 4.9e-50 169.8 0.1 5.6e-50 169.5 0.1 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KFO99135.1 - 2.8e-08 34.1 0.2 6.4e-08 32.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFO99135.1 - 5.1e-07 30.5 0.0 8.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 KFO99135.1 - 2.8e-05 23.5 1.2 0.00013 21.4 0.8 1.9 1 1 0 1 1 1 1 Dephospho-CoA kinase MobB PF03205.9 KFO99135.1 - 0.0048 16.5 0.5 0.059 13.0 0.3 2.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KFO99135.1 - 0.04 13.8 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFO99135.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KFO99135.1 - 0.081 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KFO99135.1 - 0.082 11.9 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 KFO99135.1 - 0.11 12.1 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NTPase LTXXQ PF07813.7 KFO99135.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein Dispanin PF04505.7 KFO99137.1 - 2.7e-18 65.2 0.4 3.4e-18 64.9 0.3 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF3278 PF11683.3 KFO99137.1 - 0.043 13.8 0.1 0.048 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF4184 PF13803.1 KFO99137.1 - 0.049 12.9 0.1 0.059 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) GNVR PF13807.1 KFO99137.1 - 0.16 11.7 0.5 0.89 9.3 0.0 1.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF4190 PF13828.1 KFO99137.1 - 4.5 6.8 7.3 37 3.9 4.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) RasGEF PF00617.14 KFO99138.1 - 7.1e-54 182.3 0.4 1.5e-53 181.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFO99138.1 - 5.6e-12 45.6 0.3 2.8e-11 43.4 0.2 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif Med27 PF11571.3 KFO99139.1 - 3.6e-26 91.1 0.1 7.8e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 NaeI PF09126.5 KFO99139.1 - 0.084 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI Laminin_N PF00055.12 KFO99140.1 - 1.7e-29 102.5 0.0 3.4e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFO99140.1 - 1.6e-21 75.9 66.8 3.6e-09 36.4 9.5 4.6 3 1 1 4 4 4 3 Laminin EGF-like (Domains III and V) EGF PF00008.22 KFO99140.1 - 0.001 18.9 7.9 0.001 18.9 5.5 5.0 3 1 0 3 3 3 1 EGF-like domain EGF_2 PF07974.8 KFO99140.1 - 0.0072 16.4 9.6 0.0072 16.4 6.7 6.0 5 0 0 5 5 5 1 EGF-like domain BNR PF02012.15 KFO99140.1 - 0.012 15.3 1.1 0.93 9.5 0.0 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat hEGF PF12661.2 KFO99140.1 - 0.065 13.3 0.5 0.065 13.3 0.4 5.8 8 0 0 8 8 8 0 Human growth factor-like EGF AAA_11 PF13086.1 KFO99141.1 - 3.7e-57 193.6 2.0 1.3e-56 191.8 0.5 2.8 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 KFO99141.1 - 2.5e-54 183.7 0.4 7.8e-54 182.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFO99141.1 - 3.3e-09 36.3 0.0 2e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KFO99141.1 - 4.4e-06 26.3 3.7 0.3 10.5 0.0 4.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KFO99141.1 - 7.6e-05 22.3 0.0 0.085 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFO99141.1 - 0.00036 20.6 1.0 0.0025 17.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFO99141.1 - 0.005 16.8 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF4164 PF13747.1 KFO99141.1 - 0.039 14.0 7.7 0.13 12.4 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) UvrD_C_2 PF13538.1 KFO99141.1 - 0.069 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Myb_DNA-bind_6 PF13921.1 KFO99142.1 - 3.1e-17 62.4 6.0 9.5e-14 51.2 0.2 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFO99142.1 - 3.4e-13 49.4 4.2 3e-07 30.3 0.0 4.1 4 1 0 4 4 4 2 Myb-like DNA-binding domain Poxvirus_B22R_N PF13169.1 KFO99142.1 - 0.0012 18.9 2.8 0.0019 18.3 0.1 2.6 3 0 0 3 3 3 1 Poxvirus B22R protein N-terminal WbqC PF08889.6 KFO99142.1 - 0.027 13.9 0.0 0.068 12.6 0.0 1.7 1 0 0 1 1 1 0 WbqC-like protein family Fib_alpha PF08702.5 KFO99142.1 - 0.12 12.5 0.4 0.49 10.5 0.0 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Myb_DNA-bind_4 PF13837.1 KFO99142.1 - 0.48 10.5 12.2 0.24 11.5 4.0 3.2 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Homeobox PF00046.24 KFO99143.1 - 1e-22 79.5 5.7 1.6e-22 78.8 4.0 1.3 1 0 0 1 1 1 1 Homeobox domain SAGA-Tad1 PF12767.2 KFO99143.1 - 4.1e-05 23.3 0.2 4.8e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Homez PF11569.3 KFO99143.1 - 0.15 11.1 1.2 0.28 10.2 0.8 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Helicase_C PF00271.26 KFO99144.1 - 7.6e-24 83.3 0.0 1.8e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFO99144.1 - 3.5e-22 78.6 0.0 1.2e-21 76.9 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFO99144.1 - 4.3e-17 61.3 0.1 8.9e-17 60.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFO99144.1 - 0.0027 17.5 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KFO99144.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain SecA_DEAD PF07517.9 KFO99144.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain zf-TFIIIC PF12660.2 KFO99145.1 - 1.4e-09 37.7 0.1 4.8e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ANATO PF01821.13 KFO99146.1 - 1.7 8.8 11.3 3.3 7.9 0.7 3.4 1 1 2 3 3 3 0 Anaphylotoxin-like domain Ubiq-Cytc-red_N PF09165.5 KFO99147.1 - 1.1e-29 102.4 4.8 1.1e-29 102.4 3.3 2.0 2 0 0 2 2 2 1 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal UCR_TM PF02921.9 KFO99147.1 - 4.8e-24 84.3 5.1 8.1e-24 83.6 3.5 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KFO99147.1 - 3.7e-17 61.6 0.1 8.3e-17 60.5 0.1 1.7 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Oxidored_q6 PF01058.17 KFO99147.1 - 0.081 12.5 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Isochorismatase PF00857.15 KFO99147.1 - 0.13 12.1 0.4 3.5 7.5 0.3 2.1 1 1 0 1 1 1 0 Isochorismatase family I-set PF07679.11 KFO99148.1 - 0.0083 15.9 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin I-set domain V-set PF07686.12 KFO99148.1 - 0.018 14.9 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain UPF0086 PF01868.11 KFO99149.1 - 2.4e-18 65.5 2.2 4.3e-18 64.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function UPF0086 FYVE PF01363.16 KFO99150.1 - 1.4e-18 66.4 7.3 2.7e-18 65.6 5.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 KFO99150.1 - 9.7e-13 48.2 0.2 1.6e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 KFO99150.1 - 0.001 18.9 8.1 0.0016 18.2 5.5 1.4 1 1 0 1 1 1 1 FYVE-type zinc finger PAP_RNA-bind PF04926.10 KFO99150.1 - 0.023 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain PH_11 PF15413.1 KFO99150.1 - 0.095 12.9 0.1 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.1 KFO99150.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain RdgC PF04381.7 KFO99150.1 - 0.16 10.9 1.0 0.17 10.7 0.1 1.4 2 0 0 2 2 2 0 Putative exonuclease, RdgC IBR PF01485.16 KFO99150.1 - 0.94 9.4 8.7 3.4 7.6 6.0 1.9 1 1 0 1 1 1 0 IBR domain OrfB_Zn_ribbon PF07282.6 KFO99150.1 - 1.5 8.5 7.0 3.2 7.4 4.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_4 PF14570.1 KFO99150.1 - 5.5 6.6 10.2 42 3.8 0.0 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF456 PF04306.8 KFO99151.1 - 0.0095 15.9 2.6 0.0095 15.9 1.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.1 KFO99151.1 - 0.14 11.6 12.4 0.22 11.0 8.6 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 KFO99151.1 - 2.2 7.9 6.8 0.8 9.3 3.1 1.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Cyclin_N PF00134.18 KFO99152.1 - 5.3e-44 148.8 1.4 9.9e-44 147.9 1.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFO99152.1 - 7.5e-11 42.0 0.3 2.9e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Prefoldin PF02996.12 KFO99153.1 - 2.7e-16 59.2 0.0 2.7e-16 59.2 0.0 2.2 3 0 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.1 KFO99153.1 - 4.4e-10 39.2 0.9 1.3e-09 37.7 0.0 2.3 2 1 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 KFO99153.1 - 0.1 13.5 0.3 0.1 13.5 0.2 4.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3835) Birna_RdRp PF04197.7 KFO99153.1 - 0.14 10.1 3.0 0.19 9.7 2.1 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) zf-C2H2 PF00096.21 KFO99154.1 - 8e-30 101.3 74.2 2.4e-05 24.4 2.4 10.7 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO99154.1 - 1e-26 91.2 70.7 0.00084 19.5 1.6 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFO99154.1 - 3.4e-24 83.8 82.0 1.9e-08 34.1 1.7 12.7 13 0 0 13 13 12 7 Zinc-finger double domain zf-Di19 PF05605.7 KFO99154.1 - 7.8e-07 29.1 49.9 0.015 15.3 0.7 8.1 6 3 1 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFO99154.1 - 0.00012 22.0 7.2 0.0016 18.5 1.8 10.0 10 0 0 10 10 10 4 C2H2-type zinc-finger domain GAGA PF09237.6 KFO99154.1 - 0.00032 20.2 10.0 0.58 9.7 0.1 5.9 5 2 2 7 7 7 2 GAGA factor zf-C2H2_2 PF12756.2 KFO99154.1 - 0.0031 17.5 42.1 3.5 7.7 0.1 9.9 5 3 3 9 9 9 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFO99154.1 - 0.061 13.4 0.3 0.061 13.4 0.2 9.2 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding C1_3 PF07649.7 KFO99154.1 - 1.5 8.8 15.8 3.9 7.6 0.1 5.3 5 0 0 5 5 5 0 C1-like domain Rad50_zn_hook PF04423.9 KFO99154.1 - 1.6 8.2 13.4 1.5 8.3 0.1 5.5 5 0 0 5 5 5 0 Rad50 zinc hook motif TerY-C PF15616.1 KFO99154.1 - 1.8 8.5 11.6 4.7 7.1 0.1 3.8 4 0 0 4 4 4 0 TerY-C metal binding domain zf-CHCC PF10276.4 KFO99154.1 - 1.8 8.4 27.1 0.7 9.7 0.1 6.4 6 0 0 6 6 6 0 Zinc-finger domain zf-C2H2_2 PF12756.2 KFO99155.1 - 1.4e-10 41.1 20.7 0.0048 16.9 0.8 5.2 3 2 0 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KFO99155.1 - 1.6e-08 34.3 27.4 0.07 13.5 1.0 5.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO99155.1 - 5.8e-07 29.4 17.3 0.052 13.8 1.6 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO99155.1 - 1e-05 25.2 16.5 0.14 12.1 0.4 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger DUF678 PF05077.7 KFO99155.1 - 0.0011 18.8 1.3 3.5 7.6 0.0 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF678) zf-met PF12874.2 KFO99155.1 - 0.0034 17.5 10.1 0.021 14.9 1.5 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF3222 PF11519.3 KFO99155.1 - 0.063 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) Homeobox PF00046.24 KFO99155.1 - 0.095 12.3 0.4 0.38 10.4 0.1 2.3 2 0 0 2 2 2 0 Homeobox domain PyrI_C PF02748.10 KFO99155.1 - 0.2 11.1 2.2 2.3 7.7 0.1 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.11 KFO99155.1 - 0.43 10.5 5.4 0.53 10.1 0.1 3.3 3 0 0 3 3 3 0 AN1-like Zinc finger zf-H2C2_2 PF13465.1 KFO99155.1 - 1.1 9.7 14.0 1.2 9.6 0.1 5.0 5 0 0 5 5 4 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 KFO99155.1 - 1.1 9.2 12.1 4.8 7.2 0.0 4.9 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KFO99155.1 - 1.4 9.1 20.5 0.21 11.7 0.7 5.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.1 KFO99155.1 - 8.8 6.1 7.4 33 4.2 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 KFO99156.1 - 7.1e-15 54.1 74.1 0.00058 20.0 1.4 9.8 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO99156.1 - 9.2e-10 38.2 80.4 0.045 14.1 2.7 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KFO99156.1 - 9.7e-09 34.9 76.8 0.011 15.8 0.1 9.9 9 0 0 9 9 9 6 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KFO99156.1 - 7.1e-08 32.3 78.7 0.00032 20.8 1.3 11.9 12 1 0 12 12 12 5 Zinc-finger double domain AKAP95 PF04988.7 KFO99156.1 - 0.71 9.6 34.9 0.19 11.4 0.3 7.0 6 1 1 7 7 7 0 A-kinase anchoring protein 95 (AKAP95) GAGA PF09237.6 KFO99156.1 - 9.1 5.9 9.4 0.56 9.8 0.3 3.2 3 0 0 3 3 3 0 GAGA factor Dpy19 PF10034.4 KFO99157.1 - 2.2e-225 749.6 28.4 2.6e-225 749.4 19.7 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Cadherin PF00028.12 KFO99158.1 - 1e-218 708.4 15.0 3.3e-19 68.9 0.0 15.3 15 0 0 15 15 15 15 Cadherin domain Laminin_G_2 PF02210.19 KFO99158.1 - 5.9e-33 113.6 0.2 3e-15 56.3 0.0 2.7 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFO99158.1 - 4.7e-22 78.3 0.0 5.8e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 Laminin G domain Cadherin_C PF01049.12 KFO99158.1 - 2.2e-10 40.7 0.6 4.7e-10 39.6 0.4 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFO99158.1 - 5.9e-08 32.1 0.0 0.069 12.7 0.0 6.6 7 0 0 7 7 7 1 Cadherin-like EGF PF00008.22 KFO99158.1 - 1.6e-05 24.7 37.1 0.0054 16.6 6.9 3.7 3 0 0 3 3 3 3 EGF-like domain cEGF PF12662.2 KFO99158.1 - 0.0027 17.3 23.3 0.013 15.0 0.5 3.7 3 0 0 3 3 3 2 Complement Clr-like EGF-like hEGF PF12661.2 KFO99158.1 - 0.0057 16.6 5.6 0.0057 16.6 3.9 3.8 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.8 KFO99158.1 - 0.13 12.4 46.2 0.085 13.0 8.1 3.6 3 0 0 3 3 3 0 EGF-like domain dsDNA_bind PF01984.15 KFO99159.1 - 2.7e-30 104.5 3.5 3e-30 104.3 2.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI PF01399.22 KFO99159.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.3 1 1 0 1 1 1 0 PCI domain Ank_2 PF12796.2 KFO99160.1 - 2.2e-76 252.2 14.9 2.8e-21 75.6 1.2 6.7 3 2 4 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFO99160.1 - 1.5e-75 245.4 25.3 3.2e-12 45.5 0.1 10.2 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KFO99160.1 - 2e-53 177.1 18.3 7.1e-11 41.9 0.7 10.0 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO99160.1 - 7.9e-53 175.9 13.8 1.5e-11 44.5 0.1 9.1 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO99160.1 - 1.3e-47 155.0 14.3 1.4e-06 27.9 0.0 11.2 11 0 0 11 11 11 9 Ankyrin repeat VPS9 PF02204.13 KFO99160.1 - 2e-23 82.3 0.4 6.9e-23 80.6 0.3 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Syntaxin_2 PF14523.1 KFO99161.1 - 3.9e-07 30.0 0.2 1.4e-06 28.2 0.2 1.8 2 0 0 2 2 2 1 Syntaxin-like protein DUF2493 PF10686.4 KFO99161.1 - 0.035 13.6 0.0 0.28 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2493) DUF1539 PF07560.6 KFO99161.1 - 0.038 13.8 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF2155 PF09923.4 KFO99161.1 - 0.04 14.0 0.4 6.2 6.9 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) Syndecan PF01034.15 KFO99161.1 - 0.093 12.3 1.9 0.17 11.5 1.3 1.5 1 0 0 1 1 1 0 Syndecan domain CRF PF00473.12 KFO99161.1 - 0.18 11.9 2.7 0.16 12.1 0.7 1.9 2 0 0 2 2 2 0 Corticotropin-releasing factor family TUDOR PF00567.19 KFO99163.1 - 1.2e-12 47.7 2.1 1.5e-12 47.4 1.4 1.1 1 0 0 1 1 1 1 Tudor domain TUDOR PF00567.19 KFO99164.1 - 3.4e-07 30.1 0.0 9e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Tudor domain DEAD PF00270.24 KFO99164.1 - 5.4e-06 26.0 0.0 1.5e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFO99164.1 - 0.056 13.3 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain AA_permease_2 PF13520.1 KFO99165.1 - 7.3e-65 219.1 39.7 9.1e-65 218.8 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFO99165.1 - 9.6e-27 93.4 38.9 1.6e-26 92.6 27.0 1.3 1 1 0 1 1 1 1 Amino acid permease BRO1 PF03097.13 KFO99167.1 - 4.4e-111 371.2 0.1 5.8e-111 370.8 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.11 KFO99167.1 - 6.4e-12 45.0 3.4 2.1e-11 43.3 2.3 1.9 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.19 KFO99167.1 - 0.00019 21.5 0.0 0.00078 19.5 0.0 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO99167.1 - 0.041 13.7 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF372 PF04036.7 KFO99167.1 - 0.066 12.6 0.0 7.4 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF372) TniQ PF06527.6 KFO99167.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 TniQ DUF1604 PF07713.8 KFO99168.1 - 1.6e-35 120.7 0.6 1.6e-35 120.7 0.4 4.4 5 1 0 5 5 5 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KFO99168.1 - 6.5e-07 29.0 0.2 6.5e-07 29.0 0.2 2.3 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 KFO99168.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 4.8 6 1 0 6 6 6 1 DExH-box splicing factor binding site WD40 PF00400.27 KFO99169.1 - 2.9e-53 175.9 33.8 9.2e-11 41.1 3.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 KFO99169.1 - 4.2e-09 36.2 0.0 7.4e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 KFO99169.1 - 4.6e-09 34.9 6.5 0.002 16.3 0.0 3.9 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFO99169.1 - 4.1e-07 28.6 0.2 7.5e-06 24.4 0.2 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 KFO99169.1 - 3.1e-05 23.7 0.7 0.064 12.9 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ PF01011.16 KFO99169.1 - 3.3e-05 23.1 0.3 0.0012 18.2 0.1 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.1 KFO99169.1 - 0.00013 22.1 0.1 1.1 9.6 0.0 3.6 4 0 0 4 4 4 2 PQQ-like domain Hira PF07569.6 KFO99169.1 - 0.16 11.1 1.4 2 7.6 0.0 3.0 2 2 1 3 3 3 0 TUP1-like enhancer of split Ldl_recept_a PF00057.13 KFO99170.1 - 8.9e-39 131.1 84.6 8.7e-12 44.7 8.4 5.5 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A CUB PF00431.15 KFO99170.1 - 2.9e-33 114.2 0.4 5.1e-22 78.0 0.0 2.4 2 0 0 2 2 2 2 CUB domain AA_permease_2 PF13520.1 KFO99171.1 - 1.7e-61 208.0 43.9 2.1e-61 207.7 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFO99171.1 - 4.7e-37 127.4 36.6 5.9e-37 127.1 25.4 1.1 1 0 0 1 1 1 1 Amino acid permease bZIP_2 PF07716.10 KFO99172.1 - 4.5e-16 58.4 17.0 6.2e-16 57.9 11.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFO99172.1 - 5.6e-06 26.2 12.6 9.4e-06 25.4 8.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF572 PF04502.8 KFO99172.1 - 0.001 18.4 1.1 0.001 18.4 0.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) IncA PF04156.9 KFO99172.1 - 0.011 15.3 0.3 0.012 15.1 0.2 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KFO99172.1 - 0.02 12.7 5.6 0.024 12.5 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL6 PF01763.11 KFO99172.1 - 0.022 12.9 1.2 0.024 12.8 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Seryl_tRNA_N PF02403.17 KFO99172.1 - 0.032 14.2 7.8 0.051 13.6 5.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_Maf PF03131.12 KFO99172.1 - 0.041 14.1 7.6 0.073 13.3 5.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Atg14 PF10186.4 KFO99172.1 - 0.1 11.5 5.6 0.14 11.0 3.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KFO99172.1 - 0.2 11.1 7.4 0.23 10.9 4.3 1.6 1 1 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 KFO99172.1 - 0.3 10.0 5.9 0.35 9.8 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4094 PF13334.1 KFO99172.1 - 0.75 10.2 6.0 0.26 11.6 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) LAM_C PF12544.3 KFO99172.1 - 2.1 8.3 6.7 19 5.2 4.6 2.2 1 1 0 1 1 1 0 Lysine-2,3-aminomutase XhlA PF10779.4 KFO99172.1 - 4.2 7.3 5.9 7.6 6.5 4.1 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Peptidase_M24 PF00557.19 KFO99173.1 - 1.6e-60 204.2 0.0 2.7e-58 196.9 0.0 2.9 3 0 0 3 3 3 1 Metallopeptidase family M24 AMP_N PF05195.11 KFO99173.1 - 1.3e-41 141.1 0.0 2.3e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF870 PF05912.6 KFO99173.1 - 0.12 12.2 0.3 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) Sulfotransfer_2 PF03567.9 KFO99174.1 - 7.5e-57 192.9 3.8 9.1e-57 192.6 2.6 1.1 1 0 0 1 1 1 1 Sulfotransferase family BTB_2 PF02214.17 KFO99175.1 - 7.8e-17 61.2 0.1 1.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF4 PF05236.9 KFO99176.1 - 5.5e-83 278.2 6.7 6.3e-83 278.0 4.6 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.12 KFO99176.1 - 6.4e-05 22.8 0.3 0.2 11.6 0.0 2.5 2 0 0 2 2 2 2 TATA box binding protein associated factor (TAF) SAGA-Tad1 PF12767.2 KFO99176.1 - 0.00044 19.9 3.6 0.0079 15.8 0.0 2.2 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit SprA-related PF12118.3 KFO99176.1 - 0.079 12.2 7.8 0.093 12.0 5.4 1.2 1 0 0 1 1 1 0 SprA-related family LSM14 PF12701.2 KFO99177.1 - 2.8e-42 142.4 0.0 6.9e-42 141.1 0.0 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KFO99177.1 - 6.6e-32 110.1 8.3 6.6e-32 110.1 5.7 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KFO99177.1 - 3.8e-06 26.7 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.6 KFO99177.1 - 5.1 7.6 18.6 17 5.9 8.3 2.6 2 0 0 2 2 2 0 Glycine rich protein family TINF2_N PF14973.1 KFO99178.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus PGI PF00342.14 KFO99179.1 - 1.9e-240 798.3 0.0 2.2e-240 798.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.1 KFO99179.1 - 0.036 14.2 0.2 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) LIM PF00412.17 KFO99180.1 - 1.2e-36 124.6 38.0 3.9e-14 52.4 6.3 3.1 3 0 0 3 3 3 3 LIM domain UBACT PF02134.16 KFO99181.1 - 4.8e-27 93.3 0.1 8.2e-27 92.5 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein ThiF PF00899.16 KFO99181.1 - 3.8e-24 85.0 0.1 7.8e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.1 KFO99181.1 - 3.8e-24 84.5 1.3 3.8e-24 84.5 0.9 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KFO99181.1 - 1.2e-22 79.0 2.4 1.2e-22 79.0 1.7 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site PDCD2_C PF04194.8 KFO99182.1 - 2.1e-53 180.2 0.1 2.8e-53 179.8 0.1 1.1 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain COesterase PF00135.23 KFO99183.1 - 5.7e-164 546.7 0.0 6.4e-164 546.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFO99183.1 - 1.2e-10 41.3 1.2 3.3e-10 39.8 0.8 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFO99183.1 - 0.00029 20.1 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFO99183.1 - 0.00088 19.0 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFO99183.1 - 0.13 10.8 0.0 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF59 PF01883.14 KFO99184.1 - 1.3e-11 44.3 0.1 2.9e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function DUF59 Ras PF00071.17 KFO99185.1 - 5.9e-32 110.2 0.0 8.2e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO99185.1 - 8.4e-20 71.4 0.0 1.6e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KFO99185.1 - 0.00062 19.0 0.1 0.0073 15.5 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 KFO99185.1 - 0.0013 17.9 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 KFO99185.1 - 0.002 18.2 0.1 1 9.4 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 KFO99185.1 - 0.0076 16.5 2.4 0.044 14.0 1.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFO99185.1 - 0.011 15.7 0.1 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KFO99185.1 - 0.015 15.6 0.7 0.043 14.1 0.5 1.8 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 KFO99185.1 - 0.019 14.4 0.1 0.047 13.1 0.0 1.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DNA_ligase_A_M PF01068.16 KFO99185.1 - 0.025 13.9 0.1 4.2 6.6 0.0 2.2 1 1 1 2 2 2 0 ATP dependent DNA ligase domain AAA PF00004.24 KFO99185.1 - 0.026 14.7 1.1 0.14 12.3 0.2 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KFO99185.1 - 0.038 13.5 1.3 0.15 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFO99185.1 - 0.074 12.7 0.2 0.21 11.2 0.2 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PP2C PF00481.16 KFO99186.1 - 2.2e-39 135.4 0.0 2.2e-36 125.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Carb_anhydrase PF00194.16 KFO99187.1 - 8.7e-115 382.0 0.0 9.8e-115 381.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase ThiF PF00899.16 KFO99188.1 - 5.1e-12 45.7 0.1 3.9e-11 42.9 0.0 2.4 3 0 0 3 3 3 1 ThiF family Transket_pyr PF02779.19 KFO99188.1 - 0.018 14.5 0.3 0.039 13.4 0.2 1.5 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Atx10homo_assoc PF09759.4 KFO99189.1 - 0.0016 18.1 5.0 0.12 12.0 0.6 3.2 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.1 KFO99189.1 - 0.025 14.4 0.6 1.3 9.0 0.1 2.7 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 DLIC PF05783.6 KFO99191.1 - 1.5e-244 811.9 0.0 1.7e-244 811.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.22 KFO99191.1 - 0.0011 18.4 0.0 0.8 9.1 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KFO99191.1 - 0.0016 18.7 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 KFO99191.1 - 0.0023 18.4 0.1 0.028 14.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KFO99191.1 - 0.0042 16.5 0.2 0.009 15.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KFO99191.1 - 0.0088 16.3 0.1 0.03 14.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KFO99191.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Arf PF00025.16 KFO99191.1 - 0.029 13.6 0.2 0.38 9.9 0.0 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_16 PF13191.1 KFO99191.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KFO99191.1 - 0.041 13.3 0.2 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KFO99191.1 - 0.041 13.3 0.3 0.16 11.4 0.1 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KFO99191.1 - 0.044 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 KFO99191.1 - 0.056 12.8 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFO99191.1 - 0.059 13.5 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Kinesin PF00225.18 KFO99191.1 - 0.075 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain KaiC PF06745.8 KFO99191.1 - 0.077 12.0 0.1 0.15 11.1 0.1 1.5 1 1 0 1 1 1 0 KaiC AAA_17 PF13207.1 KFO99191.1 - 0.085 13.6 0.5 0.68 10.7 0.4 2.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFO99191.1 - 0.09 12.3 0.2 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KFO99191.1 - 0.22 10.9 1.1 0.53 9.7 0.3 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MARVEL PF01284.18 KFO99192.1 - 1.1e-13 51.2 14.8 1.6e-13 50.6 10.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain YfhO PF09586.5 KFO99192.1 - 0.00093 17.3 0.5 0.0011 17.1 0.4 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Ni_hydr_CYTB PF01292.15 KFO99192.1 - 0.014 14.8 0.2 0.019 14.3 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 NicO PF03824.11 KFO99192.1 - 0.031 13.6 0.4 0.031 13.6 0.3 1.8 1 1 1 2 2 2 0 High-affinity nickel-transport protein YbhQ PF11076.3 KFO99192.1 - 0.035 13.7 0.6 0.04 13.5 0.4 1.1 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ ABC2_membrane_5 PF13346.1 KFO99192.1 - 0.041 13.1 3.0 0.058 12.6 2.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein RseC_MucC PF04246.7 KFO99192.1 - 0.076 12.5 0.4 0.076 12.5 0.3 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NfeD PF01957.13 KFO99192.1 - 2 8.5 7.2 1.6 8.9 2.0 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding MARVEL PF01284.18 KFO99193.1 - 3.2e-09 36.7 18.4 5.8e-09 35.9 12.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain PHO4 PF01384.15 KFO99193.1 - 0.096 11.3 3.3 0.12 11.0 2.3 1.0 1 0 0 1 1 1 0 Phosphate transporter family O-antigen_lig PF13425.1 KFO99193.1 - 0.42 10.5 11.0 0.92 9.4 7.7 1.6 1 1 0 1 1 1 0 O-antigen ligase like membrane protein MARVEL PF01284.18 KFO99194.1 - 1.7e-06 27.9 17.4 4.8e-06 26.4 12.0 1.7 1 1 0 1 1 1 1 Membrane-associating domain DUF543 PF04418.7 KFO99194.1 - 0.39 10.6 1.6 0.74 9.8 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF543) Herpes_LMP1 PF05297.6 KFO99194.1 - 7.8 5.3 12.6 8.4 5.1 8.7 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) dNK PF01712.14 KFO99195.1 - 6.3e-26 91.0 0.6 6.9e-26 90.9 0.4 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 KFO99195.1 - 0.00011 22.5 0.3 0.00013 22.2 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFO99195.1 - 0.0014 18.4 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFO99195.1 - 0.004 16.5 0.1 0.0047 16.3 0.0 1.3 1 1 0 1 1 1 1 Thymidylate kinase PUB PF09409.5 KFO99196.1 - 8.7e-05 22.2 0.9 0.00016 21.3 0.1 1.8 2 0 0 2 2 2 1 PUB domain P2 PF07194.6 KFO99196.1 - 0.009 15.8 0.3 0.04 13.7 0.0 2.0 2 0 0 2 2 2 1 P2 response regulator binding domain Herpes_UL56 PF04534.7 KFO99197.1 - 0.081 12.6 0.3 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein Cadherin PF00028.12 KFO99198.1 - 2e-67 223.4 9.6 1.3e-19 70.2 0.5 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFO99198.1 - 7.4e-46 155.8 0.3 1.3e-45 155.0 0.2 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 KFO99198.1 - 0.0019 17.9 0.3 3.6 7.4 0.1 3.0 2 0 0 2 2 2 2 Cadherin prodomain like Rifin_STEVOR PF02009.11 KFO99198.1 - 0.074 12.6 0.3 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Rifin/stevor family HATPase_c PF02518.21 KFO99198.1 - 0.098 12.3 0.5 5.7 6.6 0.1 3.2 2 1 1 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Big_3_4 PF13754.1 KFO99198.1 - 8.6 6.7 14.9 0.086 13.1 1.8 4.0 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) Cadherin PF00028.12 KFO99199.1 - 8e-82 269.6 5.2 6.4e-19 68.0 0.0 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFO99199.1 - 5.5e-58 195.2 0.3 1.4e-57 193.8 0.2 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFO99199.1 - 4.4e-05 22.9 0.0 0.049 13.1 0.0 3.5 4 1 0 4 4 4 2 Cadherin-like ASFV_J13L PF05568.6 KFO99199.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Cadherin PF00028.12 KFO99200.1 - 1.3e-84 278.5 1.0 9.2e-18 64.2 0.0 5.2 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFO99200.1 - 2.9e-16 59.8 0.1 5.7e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFO99200.1 - 2.3e-05 23.8 0.0 0.4 10.2 0.0 3.7 3 0 0 3 3 3 3 Cadherin-like Cadherin_pro PF08758.6 KFO99200.1 - 0.099 12.4 0.0 2.2 8.0 0.0 2.8 2 0 0 2 2 2 0 Cadherin prodomain like ADAM_spacer1 PF05986.9 KFO99203.1 - 5.4e-34 116.4 0.0 1.1e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.14 KFO99203.1 - 1.1e-30 106.1 1.0 1.9e-30 105.3 0.7 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.14 KFO99203.1 - 1.5e-30 105.0 83.0 2.2e-10 40.4 5.9 8.0 6 1 0 6 6 6 6 Thrombospondin type 1 domain Reprolysin PF01421.14 KFO99203.1 - 4.3e-30 104.8 0.1 8.4e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease PLAC PF08686.6 KFO99203.1 - 5e-11 42.6 8.1 5e-11 42.6 5.6 4.6 5 0 0 5 5 5 1 PLAC (protease and lacunin) domain Reprolysin_2 PF13574.1 KFO99203.1 - 6.9e-11 42.5 0.2 1.6e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFO99203.1 - 8e-11 42.2 1.0 1.5e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFO99203.1 - 4.6e-08 33.6 0.1 4.5e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFO99203.1 - 6.9e-08 32.2 0.1 3.4e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like HAD PF12710.2 KFO99204.1 - 0.0075 16.4 0.0 0.0084 16.2 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NUDIX PF00293.23 KFO99205.1 - 8.4e-15 54.6 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ADH_zinc_N_2 PF13602.1 KFO99206.1 - 1.2e-12 48.8 0.0 3e-12 47.5 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFO99206.1 - 9.1e-10 38.2 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFO99206.1 - 1.8e-09 37.2 0.0 5.5e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Lectin_C PF00059.16 KFO99207.1 - 2.7e-18 66.5 0.1 4.3e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Lectin C-type domain Chordopox_A33R PF05966.7 KFO99207.1 - 0.0012 17.6 0.1 0.0017 17.1 0.1 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein GPS PF01825.16 KFO99207.1 - 0.093 12.8 0.2 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain bZIP_Maf PF03131.12 KFO99207.1 - 0.18 12.0 1.5 0.28 11.5 1.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.20 KFO99208.1 - 1.7e-19 70.3 0.1 2.5e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase WW PF00397.21 KFO99208.1 - 9.9e-18 63.6 11.6 2.2e-09 36.9 3.6 2.5 2 0 0 2 2 2 2 WW domain KR PF08659.5 KFO99208.1 - 9.8e-09 35.1 0.1 1.5e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFO99208.1 - 3.8e-07 30.1 0.0 6.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFO99208.1 - 5.9e-05 23.1 0.1 0.00027 20.9 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFO99208.1 - 0.0016 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFO99208.1 - 0.028 13.3 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PerB PF06590.6 KFO99208.1 - 0.1 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 PerB protein DUF356 PF04009.7 KFO99208.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF356) bZIP_Maf PF03131.12 KFO99209.1 - 1.9e-23 82.5 10.7 3.5e-23 81.7 7.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Maf_N PF08383.6 KFO99209.1 - 1.5e-19 69.2 1.3 2.4e-19 68.5 0.9 1.3 1 0 0 1 1 1 1 Maf N-terminal region CCDC155 PF14662.1 KFO99209.1 - 0.0081 15.7 5.2 0.014 14.9 3.6 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Mnd1 PF03962.10 KFO99209.1 - 0.015 14.9 3.1 0.02 14.5 2.1 1.2 1 0 0 1 1 1 0 Mnd1 family STAT_alpha PF01017.15 KFO99209.1 - 0.022 14.4 4.6 0.031 13.9 3.2 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain bZIP_1 PF00170.16 KFO99209.1 - 0.024 14.5 10.9 0.036 14.0 7.1 1.6 1 1 0 1 1 1 0 bZIP transcription factor DUF1192 PF06698.6 KFO99209.1 - 0.038 13.8 4.2 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF904 PF06005.7 KFO99209.1 - 0.049 13.9 10.8 1.3 9.3 7.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KFO99209.1 - 0.051 13.4 10.1 0.067 13.0 5.5 2.1 1 1 1 2 2 2 0 Basic region leucine zipper Seryl_tRNA_N PF02403.17 KFO99209.1 - 0.054 13.5 5.7 0.084 12.9 3.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 KFO99209.1 - 0.099 12.1 6.5 0.29 10.6 1.4 2.2 2 0 0 2 2 2 0 Septum formation initiator Imm38 PF15599.1 KFO99209.1 - 0.1 12.1 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Immunity protein 38 DUF1843 PF08898.5 KFO99209.1 - 0.11 12.5 6.3 0.48 10.5 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) GAS PF13851.1 KFO99209.1 - 0.11 11.6 10.0 0.21 10.7 6.9 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding vATP-synt_E PF01991.13 KFO99209.1 - 0.13 11.4 4.7 0.19 10.9 3.2 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit AKNA PF12443.3 KFO99209.1 - 0.13 12.2 4.5 0.53 10.3 3.2 1.8 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF342 PF03961.8 KFO99209.1 - 0.18 10.1 2.0 0.25 9.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 KFO99209.1 - 0.18 11.4 1.9 0.16 11.6 0.3 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 MbeD_MobD PF04899.7 KFO99209.1 - 0.6 10.0 5.0 2.6 7.9 3.5 2.0 1 1 1 2 2 2 0 MbeD/MobD like DUF2353 PF09789.4 KFO99209.1 - 0.75 8.9 8.6 1.6 7.9 6.0 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DASH_Spc19 PF08287.6 KFO99209.1 - 0.98 9.0 8.4 15 5.1 5.8 2.0 1 1 1 2 2 2 0 Spc19 DUF972 PF06156.8 KFO99209.1 - 1.3 9.3 5.3 0.8 10.0 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 KFO99209.1 - 2.3 7.8 8.0 0.29 10.7 1.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4140 PF13600.1 KFO99209.1 - 2.6 8.5 7.3 42 4.6 5.2 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.13 KFO99209.1 - 3.3 7.4 8.0 28 4.5 2.9 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper Robl_LC7 PF03259.12 KFO99210.1 - 6.2e-17 60.9 0.0 6.7e-17 60.8 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain ECH PF00378.15 KFO99211.1 - 2.8e-31 108.4 0.0 3.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Chromo PF00385.19 KFO99211.1 - 1.9e-17 62.6 1.9 4e-17 61.6 1.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cmc1 PF08583.5 KFO99212.1 - 3.4e-16 58.7 3.8 3.7e-16 58.6 2.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3452 PF11934.3 KFO99212.1 - 0.012 14.9 0.0 0.013 14.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF755 PF05501.6 KFO99212.1 - 0.027 14.5 0.5 0.031 14.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF217 PF02697.9 KFO99212.1 - 0.051 13.8 0.3 0.062 13.5 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1753 DUF1903 PF08991.5 KFO99212.1 - 0.15 12.2 3.5 0.68 10.1 2.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1903) GCK PF07802.6 KFO99212.1 - 0.81 9.8 3.8 8.6 6.5 0.2 2.1 1 1 1 2 2 2 0 GCK domain PTN_MK_C PF01091.13 KFO99212.1 - 1 9.3 3.3 1.2 9.1 0.1 2.2 1 1 2 3 3 3 0 PTN/MK heparin-binding protein family, C-terminal domain CENP-N PF05238.8 KFO99213.1 - 1.7e-69 234.8 2.8 4.2e-69 233.5 1.9 1.6 1 1 0 1 1 1 1 Kinetochore protein CHL4 like zf-C2H2_4 PF13894.1 KFO99214.1 - 1.8e-06 27.8 17.4 0.094 13.0 0.2 5.6 4 1 1 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO99214.1 - 0.0026 18.0 20.1 0.43 11.0 0.5 5.6 4 1 1 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO99214.1 - 1.9 8.9 18.6 0.32 11.3 2.5 4.1 3 0 0 3 3 3 0 Zinc-finger double domain GCV_H PF01597.14 KFO99215.1 - 8e-43 145.0 0.0 8.7e-43 144.8 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RPE65 PF03055.10 KFO99216.1 - 1.3e-125 419.7 2.0 1.5e-125 419.5 1.4 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Kelch_1 PF01344.20 KFO99217.1 - 3.5e-39 132.0 3.1 7.6e-11 41.3 0.0 6.3 6 0 0 6 6 6 4 Kelch motif BACK PF07707.10 KFO99217.1 - 4.7e-29 100.2 0.7 1.3e-28 98.8 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 KFO99217.1 - 2.3e-23 81.3 7.0 1.4e-07 31.3 0.0 6.7 3 2 3 6 6 6 3 Kelch motif Kelch_4 PF13418.1 KFO99217.1 - 4.7e-20 71.0 2.6 4.5e-08 32.7 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFO99217.1 - 7.5e-14 50.8 0.8 0.03 14.0 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 KFO99217.1 - 1.2e-13 50.7 0.4 0.00018 21.5 0.0 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain BTB PF00651.26 KFO99217.1 - 5.3e-10 39.2 0.2 1.1e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.1 KFO99217.1 - 4.3e-09 36.1 1.1 0.12 12.3 0.0 5.3 6 0 0 6 6 6 3 Kelch motif DUF1668 PF07893.8 KFO99217.1 - 0.0052 15.9 0.0 0.58 9.2 0.0 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF1668) LRR_4 PF12799.2 KFO99218.1 - 5.5e-10 38.6 6.9 0.00012 21.6 0.4 4.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFO99218.1 - 1.1e-05 25.0 10.2 0.46 10.7 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.1 KFO99218.1 - 0.00011 21.8 8.8 0.01 15.5 0.9 3.5 2 1 0 2 2 2 2 Leucine rich repeat PH PF00169.24 KFO99218.1 - 0.06 13.5 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 PH domain PI-PLC-X PF00388.14 KFO99220.1 - 2.7e-66 221.4 0.1 5.9e-66 220.3 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH2 PF00017.19 KFO99220.1 - 2.5e-47 158.5 0.4 6.8e-26 89.8 0.1 2.9 2 0 0 2 2 2 2 SH2 domain PI-PLC-Y PF00387.14 KFO99220.1 - 9.5e-42 141.7 0.0 3.1e-41 140.0 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KFO99220.1 - 2.1e-14 53.1 0.1 1.7e-13 50.1 0.0 2.5 2 0 0 2 2 2 1 C2 domain SH3_1 PF00018.23 KFO99220.1 - 3.8e-13 48.5 0.1 1.2e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFO99220.1 - 3.7e-12 45.6 0.1 1.4e-11 43.7 0.1 2.1 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFO99220.1 - 1.1e-06 28.7 2.1 0.34 11.1 0.1 4.0 3 0 0 3 3 3 3 PH domain SH3_2 PF07653.12 KFO99220.1 - 1.9e-06 27.2 0.0 5.3e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_like PF09279.6 KFO99220.1 - 2.1e-06 27.6 2.0 2.4e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like 3Beta_HSD PF01073.14 KFO99221.1 - 6.1e-71 238.3 0.0 7.9e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFO99221.1 - 3.9e-25 88.6 0.0 5.2e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFO99221.1 - 1.7e-12 46.8 0.0 2.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFO99221.1 - 2.3e-10 39.8 0.1 6.6e-10 38.3 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KFO99221.1 - 1.2e-08 35.2 0.0 1.8e-08 34.6 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFO99221.1 - 6.9e-07 28.4 0.5 2.4e-06 26.6 0.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFO99221.1 - 0.2 11.5 0.9 1.3 8.8 0.6 2.1 1 1 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.20 KFO99222.1 - 2.1e-25 89.5 0.0 2.7e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFO99222.1 - 3.3e-12 46.7 0.0 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFO99222.1 - 6.7e-05 22.1 0.0 0.00011 21.5 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KFO99222.1 - 7e-05 22.5 0.0 9.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Acetyltransf_2 PF00797.12 KFO99223.1 - 8.8e-90 300.4 0.1 1e-89 300.2 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase Ribosomal_L40e PF01020.12 KFO99223.1 - 0.13 11.8 0.3 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L40e family Acetyltransf_2 PF00797.12 KFO99224.1 - 1.1e-87 293.5 0.1 1.3e-87 293.3 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.12 KFO99225.1 - 1.5e-90 302.9 0.8 1.8e-90 302.7 0.5 1.0 1 0 0 1 1 1 1 N-acetyltransferase MPP6 PF10175.4 KFO99226.1 - 4e-33 113.9 7.4 4e-33 113.9 5.1 1.6 2 0 0 2 2 2 1 M-phase phosphoprotein 6 Cadherin PF00028.12 KFO99227.1 - 2.1e-70 233.0 4.8 5.9e-20 71.3 0.0 4.6 5 0 0 5 5 5 4 Cadherin domain MCD PF05292.6 KFO99228.1 - 7.7e-24 84.0 0.2 9.7e-24 83.7 0.1 1.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) Viral_P18 PF04521.8 KFO99228.1 - 0.066 12.6 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein zf-CCCH_2 PF14608.1 KFO99229.1 - 0.35 10.9 4.0 2.1 8.4 0.1 4.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type HSBP1 PF06825.7 KFO99231.1 - 3.3e-15 55.3 3.7 5.1e-15 54.7 2.6 1.3 1 1 0 1 1 1 1 Heat shock factor binding protein 1 UPF0184 PF03670.8 KFO99231.1 - 0.037 14.2 0.3 0.04 14.0 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF3969 PF13108.1 KFO99231.1 - 0.048 13.3 0.3 0.048 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) FlaC_arch PF05377.6 KFO99231.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 KFO99231.1 - 0.14 11.6 0.2 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Septum formation initiator Ion_trans PF00520.26 KFO99232.1 - 8.6e-29 100.2 2.0 1.9e-28 99.1 1.4 1.5 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.17 KFO99232.1 - 3.7e-25 87.9 0.0 8.7e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFO99232.1 - 3.1e-12 46.0 4.9 4e-12 45.6 1.9 2.2 2 0 0 2 2 2 1 Ion channel CECR6_TMEM121 PF14997.1 KFO99232.1 - 0.02 14.5 0.9 0.035 13.6 0.5 1.6 1 1 0 1 1 1 0 CECR6/TMEM121 family Latarcin PF10279.4 KFO99232.1 - 0.038 14.1 0.2 18 5.6 0.7 2.6 2 0 0 2 2 2 0 Latarcin precursor WAP PF00095.16 KFO99233.1 - 1.7e-06 27.8 15.2 1.7e-06 27.8 10.5 2.2 2 0 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' E1-E2_ATPase PF00122.15 KFO99234.1 - 4.5e-75 251.6 1.0 4.5e-75 251.6 0.7 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFO99234.1 - 1.7e-43 148.2 5.9 1.7e-43 148.2 4.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFO99234.1 - 2.3e-27 96.8 0.0 7.8e-27 95.0 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFO99234.1 - 3.7e-19 67.9 0.0 9.1e-19 66.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFO99234.1 - 1.5e-16 60.0 0.1 4.3e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFO99234.1 - 1.3e-11 45.0 0.0 4.1e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFO99234.1 - 0.00011 21.8 5.0 0.00041 20.0 2.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3329 PF11808.3 KFO99234.1 - 0.17 11.9 0.9 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) TLD PF07534.11 KFO99235.1 - 4.6e-39 133.5 0.3 6.8e-39 133.0 0.2 1.3 1 0 0 1 1 1 1 TLD Cofilin_ADF PF00241.15 KFO99236.1 - 8.4e-11 41.8 0.1 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Kelch_1 PF01344.20 KFO99237.1 - 2.2e-44 148.7 12.8 6.7e-11 41.5 0.0 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFO99237.1 - 1e-31 107.7 4.6 5.8e-05 23.0 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BTB PF00651.26 KFO99237.1 - 1.7e-27 95.5 0.5 8.6e-27 93.3 0.0 2.3 2 1 1 3 3 3 1 BTB/POZ domain Kelch_4 PF13418.1 KFO99237.1 - 9.1e-23 79.7 8.1 0.00031 20.4 0.0 5.8 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFO99237.1 - 5.1e-22 76.7 5.4 0.00029 20.4 0.2 6.6 6 0 0 6 6 6 4 Kelch motif BACK PF07707.10 KFO99237.1 - 3.5e-21 74.9 0.3 6.7e-21 74.0 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFO99237.1 - 4.8e-19 67.9 1.3 0.0064 16.6 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFO99237.1 - 8.9e-17 60.6 3.9 5.9e-06 26.1 0.1 5.6 6 0 0 6 6 6 3 Kelch motif UCH PF00443.24 KFO99238.1 - 7.6e-42 143.2 0.0 1.3e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO99238.1 - 8.4e-17 61.5 0.0 2.3e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PAM2 PF07145.10 KFO99238.1 - 5e-05 22.5 0.0 0.00013 21.1 0.0 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region LCCL PF03815.14 KFO99239.1 - 1.1e-50 169.5 10.7 6.2e-27 93.4 0.1 2.9 3 0 0 3 3 3 2 LCCL domain CAP PF00188.21 KFO99239.1 - 1.5e-19 70.7 4.4 3.2e-19 69.6 3.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rxt3 PF08642.5 KFO99239.1 - 3.1e-05 24.1 0.0 0.034 14.4 0.0 3.1 2 1 0 2 2 2 2 Histone deacetylation protein Rxt3 zf-C4 PF00105.13 KFO99240.1 - 7.9e-32 109.3 18.1 8.8e-32 109.1 12.5 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Foamy_virus_ENV PF03408.9 KFO99240.1 - 0.089 10.3 5.3 0.094 10.2 3.7 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein DM PF00751.13 KFO99240.1 - 5.5 6.5 14.6 1.7e+02 1.8 10.2 2.4 1 1 0 1 1 1 0 DM DNA binding domain Ank_2 PF12796.2 KFO99241.1 - 2.2e-58 194.5 16.3 4.1e-21 75.1 2.3 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFO99241.1 - 1.5e-54 179.1 21.7 2.7e-12 45.8 0.2 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KFO99241.1 - 1.3e-46 156.1 14.9 2.9e-10 40.3 0.1 5.8 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO99241.1 - 1.3e-43 146.0 30.0 1.8e-10 40.7 0.1 8.5 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO99241.1 - 1.1e-37 124.2 18.5 1.5e-05 24.8 0.1 9.3 9 0 0 9 9 9 9 Ankyrin repeat Death PF00531.17 KFO99241.1 - 1.6e-12 47.0 0.1 3.1e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Death domain PH PF00169.24 KFO99242.1 - 5.5e-11 42.5 0.5 9.5e-11 41.8 0.4 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFO99242.1 - 0.0011 19.0 0.3 0.062 13.4 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFO99242.1 - 0.02 15.1 1.1 0.11 12.6 0.8 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.2 KFO99242.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Peptidase_S8 PF00082.17 KFO99243.1 - 4.9e-56 189.9 0.3 6.5e-56 189.5 0.2 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFO99243.1 - 2.2e-32 110.6 0.1 3.6e-32 109.9 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain PLAC PF08686.6 KFO99243.1 - 2.4e-09 37.2 10.1 1.9e-08 34.4 7.0 2.7 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain GF_recep_IV PF14843.1 KFO99243.1 - 1.1e-08 34.7 75.8 1.4e-06 27.9 7.5 3.9 1 1 2 3 3 3 2 Growth factor receptor domain IV LRR_9 PF14580.1 KFO99244.1 - 1.4e-93 311.3 0.8 1.7e-93 311.0 0.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KFO99244.1 - 6.8e-12 44.7 4.1 7.2e-06 25.4 0.7 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO99244.1 - 2.4e-08 33.5 12.7 7.1e-06 25.6 2.1 2.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KFO99244.1 - 0.0012 18.5 4.3 5.3 7.4 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KFO99244.1 - 0.034 14.2 4.8 6.4 7.4 0.1 3.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KFO99244.1 - 0.076 13.1 5.8 3.4 8.0 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Selenoprotein_S PF06936.6 KFO99245.1 - 2.3e-57 193.5 8.4 2.6e-57 193.4 5.8 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) DREPP PF05558.7 KFO99245.1 - 0.47 10.2 4.9 0.57 9.9 3.4 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide CHGN PF05679.11 KFO99246.1 - 1e-187 624.8 0.5 1.2e-187 624.5 0.3 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.11 KFO99246.1 - 7.4e-14 51.5 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.9 KFO99246.1 - 1e-11 44.1 0.1 2.5e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFO99246.1 - 1.7e-08 33.9 0.0 3.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.16 KFO99246.1 - 0.0002 21.0 0.1 0.0041 16.7 0.0 2.9 2 1 0 2 2 2 1 Galactosyltransferase Glyco_transf_21 PF13506.1 KFO99246.1 - 0.0064 15.7 0.0 0.04 13.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFO99246.1 - 0.047 13.3 0.0 2.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 2 Pkinase PF00069.20 KFO99247.1 - 4.1e-43 147.4 0.0 7.4e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99247.1 - 4.4e-37 127.5 0.0 7.5e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.2 KFO99247.1 - 2.5e-27 93.9 32.5 5.7e-06 25.8 0.7 8.4 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO99247.1 - 4.2e-26 90.4 23.8 3.6e-09 36.2 1.2 6.7 6 0 0 6 6 6 5 Leucine rich repeat Ank_2 PF12796.2 KFO99247.1 - 7.3e-18 64.7 0.4 3.4e-09 36.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) LRR_1 PF00560.28 KFO99247.1 - 3.4e-16 56.8 23.8 2.3 8.5 0.0 11.4 13 0 0 13 13 10 5 Leucine Rich Repeat Miro PF08477.8 KFO99247.1 - 6.5e-10 39.5 0.0 1.7e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Ank PF00023.25 KFO99247.1 - 2.4e-09 36.5 2.1 0.063 13.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFO99247.1 - 5.7e-09 35.3 1.3 0.76 10.1 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat LRR_7 PF13504.1 KFO99247.1 - 1.1e-08 33.8 26.5 0.19 12.0 0.1 11.1 12 0 0 12 12 10 1 Leucine rich repeat Ank_5 PF13857.1 KFO99247.1 - 4.3e-07 29.9 3.7 1.5 9.1 0.0 4.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO99247.1 - 2.5e-06 27.8 0.4 0.042 14.3 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ras PF00071.17 KFO99247.1 - 3.6e-06 26.4 0.0 7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFO99247.1 - 1.4e-05 24.4 0.0 3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_6 PF13516.1 KFO99247.1 - 0.00042 20.0 23.1 0.028 14.4 0.1 9.4 11 0 0 11 11 9 1 Leucine Rich repeat MMR_HSR1 PF01926.18 KFO99247.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase malic PF00390.14 KFO99247.1 - 0.02 14.4 0.3 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain Gtr1_RagA PF04670.7 KFO99247.1 - 0.033 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Aldedh PF00171.17 KFO99248.1 - 1.4e-188 627.0 0.0 1.5e-188 626.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFO99248.1 - 0.00025 19.9 0.0 0.00051 18.8 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KFO99248.1 - 0.0059 15.8 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Ank PF00023.25 KFO99249.1 - 4.7e-41 136.5 1.6 1.5e-07 30.8 0.0 7.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_2 PF12796.2 KFO99249.1 - 2.8e-40 136.5 0.0 2.8e-13 50.0 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO99249.1 - 6e-31 106.2 1.0 8.1e-11 42.1 0.0 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO99249.1 - 2.7e-30 103.6 4.2 9e-08 32.1 0.1 6.0 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO99249.1 - 3.1e-22 76.4 1.4 1.1e-05 25.2 0.0 6.8 8 0 0 8 8 8 4 Ankyrin repeat SOCS_box PF07525.11 KFO99249.1 - 1.3e-13 50.4 1.6 4.2e-13 48.9 1.1 1.9 1 0 0 1 1 1 1 SOCS box LINES_N PF14694.1 KFO99250.1 - 5.5e-102 341.4 3.1 8.5e-102 340.8 2.1 1.3 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.1 KFO99250.1 - 1.3e-18 65.9 0.6 3.4e-18 64.5 0.4 1.8 1 0 0 1 1 1 1 Lines C-terminus ADAM_spacer1 PF05986.9 KFO99251.1 - 2.9e-28 98.0 0.0 4.9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFO99251.1 - 1.5e-23 83.4 0.7 3.7e-18 65.8 0.1 2.7 2 0 0 2 2 2 2 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 KFO99251.1 - 1e-15 57.5 79.1 5.6e-10 39.1 7.0 7.3 6 1 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 KFO99251.1 - 7.2e-13 48.9 1.3 3.2e-12 46.7 0.9 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFO99251.1 - 9.4e-10 39.0 0.0 2.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.6 KFO99251.1 - 4e-09 36.6 15.4 4.8e-09 36.3 8.0 3.3 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Reprolysin_4 PF13583.1 KFO99251.1 - 1.7e-08 34.2 0.2 1.4e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFO99251.1 - 3.1e-07 30.6 1.2 3.1e-07 30.6 0.8 2.8 2 2 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFO99251.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KFO99251.1 - 0.15 10.9 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 SRF-TF PF00319.13 KFO99252.1 - 4.5e-22 77.0 0.2 7.9e-22 76.2 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.3 KFO99252.1 - 7.7e-06 25.3 0.0 2.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat LRR_8 PF13855.1 KFO99253.1 - 7.9e-23 79.9 19.7 1.9e-12 46.7 0.7 4.7 2 2 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 KFO99253.1 - 5.4e-21 73.7 25.8 7.4e-08 31.8 0.2 5.1 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO99253.1 - 4.8e-14 50.2 22.3 0.16 12.0 0.0 9.4 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 KFO99253.1 - 2e-09 36.0 24.2 0.34 11.2 0.2 9.1 9 1 1 10 10 10 5 Leucine rich repeat LRR_9 PF14580.1 KFO99253.1 - 0.0024 17.4 5.9 0.0092 15.5 0.4 2.8 2 1 2 4 4 4 1 Leucine-rich repeat LRR_6 PF13516.1 KFO99253.1 - 0.089 12.9 18.8 5.8 7.3 0.0 7.3 8 2 0 8 8 8 0 Leucine Rich repeat Filament PF00038.16 KFO99254.1 - 8.9e-27 94.3 33.6 8.9e-27 94.3 23.3 3.1 2 1 0 2 2 2 1 Intermediate filament protein Pkinase_Tyr PF07714.12 KFO99255.1 - 4.6e-97 324.1 0.0 6.7e-97 323.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO99255.1 - 1.3e-42 145.7 0.0 2e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Furin-like PF00757.15 KFO99255.1 - 7.5e-33 113.2 33.6 7.5e-33 113.2 23.3 2.1 2 0 0 2 2 2 1 Furin-like cysteine rich region Recep_L_domain PF01030.19 KFO99255.1 - 1.3e-29 102.4 0.8 2.5e-29 101.4 0.5 1.5 1 0 0 1 1 1 1 Receptor L domain fn3 PF00041.16 KFO99255.1 - 5.6e-19 68.0 8.0 1.2e-06 28.5 0.0 4.7 4 1 0 4 4 4 4 Fibronectin type III domain Kinase-like PF14531.1 KFO99255.1 - 0.00019 20.4 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Peptidase_C15 PF01470.12 KFO99256.1 - 1.8e-20 73.6 0.0 2.3e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase DUF976 PF06162.7 KFO99256.1 - 0.00018 21.0 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Caenorhabditis elegans protein of unknown function (DUF976) Acetyltransf_7 PF13508.1 KFO99257.1 - 0.0011 19.0 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFO99257.1 - 0.023 14.8 0.0 0.082 13.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glutaredoxin PF00462.19 KFO99258.1 - 1.3e-39 133.9 0.1 1.8e-17 63.0 0.0 3.6 4 0 0 4 4 4 2 Glutaredoxin Thioredoxin PF00085.15 KFO99258.1 - 9e-19 67.0 0.1 3.3e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 KFO99258.1 - 2.8e-07 30.7 0.1 2.5e-05 24.4 0.0 3.5 3 2 1 4 4 3 1 Thioredoxin-like domain SH3BGR PF04908.10 KFO99258.1 - 3.1e-05 23.8 0.0 0.079 12.9 0.0 2.6 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein DIM1 PF02966.11 KFO99258.1 - 7.7e-05 22.2 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Mitosis protein DIM1 ArsC PF03960.10 KFO99258.1 - 0.00018 21.5 0.0 2 8.5 0.0 3.4 3 0 0 3 3 3 1 ArsC family Thioredoxin_8 PF13905.1 KFO99258.1 - 0.00041 20.4 0.1 0.048 13.7 0.0 3.2 2 1 1 3 3 3 1 Thioredoxin-like Phosducin PF02114.11 KFO99258.1 - 0.0045 15.7 0.0 0.0084 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosducin DNA_processg_A PF02481.10 KFO99258.1 - 0.0091 14.9 0.0 2.6 6.8 0.0 3.6 5 0 0 5 5 5 1 DNA recombination-mediator protein A Thioredoxin_3 PF13192.1 KFO99258.1 - 0.017 14.8 0.1 0.081 12.7 0.0 2.1 2 1 0 2 2 2 0 Thioredoxin domain TrbC_Ftype PF09673.5 KFO99258.1 - 0.04 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Fe-ADH PF00465.14 KFO99258.1 - 0.11 11.1 0.0 2.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase YodA PF09223.6 KFO99258.1 - 0.15 11.7 0.0 15 5.1 0.0 2.3 2 0 0 2 2 2 0 YodA lipocalin-like domain TIG PF01833.19 KFO99259.1 - 9.3e-13 47.9 0.1 9.3e-13 47.9 0.1 2.5 2 0 0 2 2 2 1 IPT/TIG domain DNA_binding_1 PF01035.15 KFO99260.1 - 3.7e-26 90.6 0.0 4.8e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.10 KFO99260.1 - 2.8e-08 34.2 0.0 4.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain MAGP PF05507.6 KFO99263.1 - 0.052 13.3 1.4 0.37 10.6 0.1 2.1 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) K167R PF08065.7 KFO99265.1 - 3.1e-19 69.1 7.0 1e-08 35.2 0.2 2.7 1 1 2 3 3 3 3 K167R (NUC007) repeat BaffR-Tall_bind PF09256.5 KFO99265.1 - 0.0014 18.1 8.9 6.6 6.3 0.1 4.9 5 0 0 5 5 5 3 BAFF-R, TALL-1 binding cIII PF08134.6 KFO99265.1 - 0.0084 15.6 7.8 4.2 7.0 0.0 4.7 1 1 4 5 5 5 2 cIII protein family Sybindin PF04099.7 KFO99265.1 - 0.065 12.9 0.0 0.49 10.0 0.0 1.9 1 1 1 2 2 2 0 Sybindin-like family Complex1_LYR PF05347.10 KFO99265.1 - 0.11 12.3 0.2 3 7.7 0.0 3.1 2 2 1 3 3 3 0 Complex 1 protein (LYR family) Prim_Zn_Ribbon PF08273.7 KFO99266.1 - 0.081 13.0 4.4 21 5.2 0.3 3.4 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase DAN PF03045.10 KFO99266.1 - 0.11 11.9 5.5 3.3 7.1 0.1 2.3 1 1 1 2 2 2 0 DAN domain TGF_beta_GS PF08515.7 KFO99266.1 - 9.1 5.7 7.2 69 2.8 0.1 3.6 4 0 0 4 4 4 0 Transforming growth factor beta type I GS-motif PP1_bind PF15276.1 KFO99268.1 - 4.9e-25 87.3 0.7 4.9e-25 87.3 0.5 1.5 2 0 0 2 2 2 1 Protein phosphatase 1 binding FHA PF00498.21 KFO99269.1 - 9.7e-15 54.4 0.0 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 FHA domain Claudin_2 PF13903.1 KFO99270.1 - 9e-11 41.7 9.4 1.3e-10 41.2 6.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Ni_hydr_CYTB PF01292.15 KFO99270.1 - 0.16 11.3 1.1 0.72 9.2 1.0 1.8 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 YoqO PF14037.1 KFO99270.1 - 0.88 9.6 6.7 1.9 8.5 0.3 2.9 3 0 0 3 3 3 0 YoqO-like protein DUF4006 PF13179.1 KFO99270.1 - 2.7 7.6 4.5 33 4.1 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Baculo_11_kDa PF06143.6 KFO99270.1 - 3.4 7.0 5.7 7.8 5.9 0.1 3.4 4 0 0 4 4 4 0 Baculovirus 11 kDa family Yip1 PF04893.12 KFO99270.1 - 9.4 5.6 14.2 61 3.0 7.6 2.8 2 1 0 2 2 2 0 Yip1 domain Fork_head PF00250.13 KFO99271.1 - 2.3e-42 142.9 0.1 2.7e-42 142.7 0.1 1.0 1 0 0 1 1 1 1 Fork head domain FAM196 PF15265.1 KFO99273.1 - 4.4e-161 537.6 16.6 7.5e-96 322.3 3.2 2.0 1 1 1 2 2 2 2 FAM196 family DUF964 PF06133.6 KFO99273.1 - 6.1 6.9 8.3 0.7 9.9 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF964) Herpes_BBRF1 PF04793.7 KFO99274.1 - 0.038 12.7 0.3 0.039 12.7 0.2 1.1 1 0 0 1 1 1 0 BRRF1-like protein RTTN_N PF14726.1 KFO99274.1 - 0.059 13.9 0.1 0.059 13.9 0.1 1.1 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning Glu_syn_central PF04898.9 KFO99274.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Rota_NS6 PF04866.7 KFO99274.1 - 0.13 12.2 0.4 3.3 7.7 0.1 2.0 1 1 1 2 2 2 0 Rotavirus non-structural protein 6 Flu_C_NS2 PF03555.9 KFO99274.1 - 0.14 12.0 0.3 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) DOCK-C2 PF14429.1 KFO99275.1 - 4.4e-32 111.2 0.0 6.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins ALMS_motif PF15309.1 KFO99276.1 - 7.4e-33 113.3 13.1 1.5e-32 112.3 9.1 1.5 1 0 0 1 1 1 1 ALMS motif Reprolysin PF01421.14 KFO99277.1 - 2.7e-71 239.2 0.0 2.7e-71 239.2 0.0 1.6 2 0 0 2 2 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFO99277.1 - 6.1e-35 119.8 3.0 6.1e-35 119.8 2.0 3.2 3 1 0 3 3 2 1 ADAM cysteine-rich Pep_M12B_propep PF01562.14 KFO99277.1 - 6.8e-34 116.4 0.1 1.1e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFO99277.1 - 7.7e-24 83.7 21.8 7.7e-24 83.7 15.1 3.6 4 0 0 4 4 3 1 Disintegrin Reprolysin_5 PF13688.1 KFO99277.1 - 7.6e-21 74.9 0.0 1.5e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFO99277.1 - 1.7e-15 57.4 0.0 2.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFO99277.1 - 2.2e-15 57.2 0.0 4.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFO99277.1 - 2.6e-15 56.5 0.0 4.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 KFO99277.1 - 0.0069 16.0 0.1 0.018 14.6 0.1 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.4 KFO99277.1 - 0.084 11.7 0.3 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF1025 PF06262.6 KFO99277.1 - 0.21 11.3 0.2 0.41 10.4 0.1 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase HA2 PF04408.18 KFO99278.1 - 2.1e-21 75.8 0.3 6.4e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFO99278.1 - 1.2e-14 54.1 0.0 3.4e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KFO99278.1 - 0.034 14.2 0.0 0.15 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain BCIP PF13862.1 KFO99279.1 - 1.1e-57 194.7 3.6 1.3e-57 194.4 2.5 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DPRP PF04244.8 KFO99279.1 - 0.01 15.3 0.1 0.34 10.4 0.0 2.2 1 1 1 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein Orthopox_B11R PF07033.6 KFO99279.1 - 0.06 12.8 0.3 0.14 11.6 0.2 1.6 1 0 0 1 1 1 0 Orthopoxvirus B11R protein HEM4 PF02602.10 KFO99280.1 - 1.2e-46 158.8 0.0 1.4e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD 2-Hacid_dh_C PF02826.14 KFO99281.1 - 2.8e-55 186.2 0.0 4.7e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFO99281.1 - 6.5e-29 100.0 0.1 8.1e-29 99.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFO99281.1 - 0.03 14.1 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase OTU PF02338.14 KFO99282.1 - 1.7e-33 115.8 0.0 4.7e-33 114.3 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease zf-RanBP PF00641.13 KFO99282.1 - 8.6e-09 34.3 37.7 6.1e-06 25.2 4.3 4.0 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others DZR PF12773.2 KFO99282.1 - 2.1 8.2 20.8 3.2 7.6 4.8 3.2 2 1 1 3 3 3 0 Double zinc ribbon Methyltransf_31 PF13847.1 KFO99283.1 - 6.7e-19 67.9 0.0 9.2e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO99283.1 - 6.1e-15 55.7 0.0 8.5e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO99283.1 - 1.2e-09 38.0 0.0 2.9e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO99283.1 - 1.2e-08 35.3 0.0 1.8e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFO99283.1 - 1.3e-07 31.9 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFO99283.1 - 3.8e-06 26.9 0.0 6.7e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFO99283.1 - 1.4e-05 24.4 0.0 2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KFO99283.1 - 2.9e-05 23.3 0.0 3.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KFO99283.1 - 0.00017 21.8 0.0 0.00027 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFO99283.1 - 0.0017 17.4 0.0 0.0034 16.4 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.9 KFO99283.1 - 0.0052 15.9 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 KFO99283.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 KFO99283.1 - 0.022 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MetW PF07021.7 KFO99283.1 - 0.073 12.4 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 KFO99283.1 - 0.075 12.5 0.0 0.097 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAM53 PF15242.1 KFO99284.1 - 4e-99 332.1 19.7 3.4e-98 329.0 13.7 2.0 1 1 0 1 1 1 1 Family of FAM53 Hydrolase_like PF13242.1 KFO99285.1 - 2e-19 69.0 0.0 6.1e-19 67.5 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KFO99285.1 - 8.8e-16 57.6 0.0 1.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFO99285.1 - 2.4e-12 47.4 0.0 2.1e-08 34.5 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFO99285.1 - 2.8e-09 37.6 0.2 5.8e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Aminotran_3 PF00202.16 KFO99286.1 - 6.4e-115 383.6 0.0 7.7e-115 383.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFO99286.1 - 0.0078 15.1 0.0 0.035 13.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Sulfotransfer_1 PF00685.22 KFO99287.1 - 2.2e-15 56.6 0.0 3e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFO99287.1 - 5.7e-10 40.3 0.2 9.9e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 KFO99287.1 - 0.021 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family PVL_ORF50 PF07768.6 KFO99287.1 - 0.044 13.7 0.0 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family Peptidase_M14 PF00246.19 KFO99288.1 - 1.1e-73 248.3 0.1 1.9e-73 247.4 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.20 KFO99288.1 - 6.9e-29 100.2 0.1 1.6e-28 99.0 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain CarboxypepD_reg PF13620.1 KFO99288.1 - 1e-11 44.7 0.1 2.5e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFO99288.1 - 8.1e-05 22.5 0.3 0.00021 21.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) phage_tail_N PF08400.5 KFO99288.1 - 0.079 12.6 0.3 0.24 11.0 0.2 1.8 1 1 0 1 1 1 0 Prophage tail fibre N-terminal 7tm_1 PF00001.16 KFO99289.1 - 2.9e-37 128.2 12.0 4.2e-37 127.6 8.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFO99289.1 - 5.8e-06 25.6 14.1 7.5e-06 25.2 9.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 KFO99289.1 - 2.1e-05 23.8 11.9 5e-05 22.5 8.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.4 KFO99289.1 - 4.4e-05 22.8 6.8 4.4e-05 22.8 4.7 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Git3 PF11710.3 KFO99289.1 - 0.00011 21.8 11.2 0.00011 21.7 7.1 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF2243 PF10002.4 KFO99289.1 - 0.0084 15.8 0.3 0.024 14.3 0.2 1.8 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) ABC2_membrane_4 PF12730.2 KFO99289.1 - 0.13 11.4 15.4 0.1 11.7 8.0 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF2516 PF10724.4 KFO99289.1 - 1.9 8.5 10.8 1.3 9.0 1.7 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2516) WD40 PF00400.27 KFO99290.1 - 1.6e-28 97.5 7.4 2.7e-08 33.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Homeobox PF00046.24 KFO99291.1 - 8.9e-20 70.0 1.5 1.5e-19 69.3 1.0 1.3 1 0 0 1 1 1 1 Homeobox domain AHS1 PF02682.11 KFO99291.1 - 0.029 13.8 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Homez PF11569.3 KFO99291.1 - 0.13 11.3 0.3 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-H2C2_2 PF13465.1 KFO99292.1 - 4.1e-13 48.9 42.9 6.3e-07 29.3 2.6 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFO99292.1 - 2.4e-07 30.5 44.7 0.0024 17.9 4.2 5.3 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFO99292.1 - 2e-05 24.6 49.5 0.12 12.7 5.8 5.5 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO99292.1 - 4 7.9 50.2 0.21 11.9 3.4 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger KTI12 PF08433.5 KFO99293.1 - 4.1e-16 58.9 4.3 6.7e-16 58.2 2.7 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KFO99293.1 - 1.7e-05 24.7 0.0 6.8e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain Selenoprotein_S PF06936.6 KFO99293.1 - 0.028 13.9 1.5 0.04 13.4 1.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) AAA_18 PF13238.1 KFO99293.1 - 0.032 14.5 0.2 0.15 12.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain DUF4506 PF14958.1 KFO99294.1 - 7.4e-33 113.0 0.0 1.4e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) Death PF00531.17 KFO99296.1 - 6.4e-05 22.6 1.6 0.00014 21.6 1.1 1.6 1 0 0 1 1 1 1 Death domain AAA_22 PF13401.1 KFO99297.1 - 3.1e-06 27.3 0.0 1.3e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFO99297.1 - 8.7e-06 25.4 0.1 5.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KFO99297.1 - 0.00073 19.5 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFO99297.1 - 0.0033 17.6 0.0 0.013 15.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PQQ_2 PF13360.1 KFO99297.1 - 0.0048 16.3 0.1 0.23 10.8 0.0 2.7 2 0 0 2 2 2 1 PQQ-like domain AAA_25 PF13481.1 KFO99297.1 - 0.026 13.9 0.0 0.068 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFO99297.1 - 0.054 13.4 0.3 0.81 9.6 0.2 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KFO99297.1 - 0.32 10.7 0.0 0.85 9.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RELT PF12606.3 KFO99299.1 - 4.3e-22 76.9 0.8 7.7e-22 76.1 0.5 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 TMEM171 PF15471.1 KFO99299.1 - 0.095 11.4 0.2 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein family 171 PGM_PMM_I PF02878.11 KFO99300.1 - 2.1e-36 124.4 0.0 4e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFO99300.1 - 2.8e-23 82.1 0.0 9.1e-23 80.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KFO99300.1 - 9.9e-12 44.9 0.2 6.2e-11 42.3 0.0 2.5 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KFO99300.1 - 1.9e-05 24.6 0.0 5.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RabGAP-TBC PF00566.13 KFO99301.1 - 9.4e-52 175.5 0.9 2.4e-51 174.2 0.6 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3350 PF11830.3 KFO99301.1 - 1.6e-26 92.0 2.9 7.5e-26 89.9 2.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3350) PID PF00640.18 KFO99301.1 - 4.3e-14 52.6 3.9 1.8e-09 37.6 0.2 3.6 3 0 0 3 3 3 2 Phosphotyrosine interaction domain (PTB/PID) FANCI_S1-cap PF14674.1 KFO99301.1 - 6.8 6.8 7.8 7.6 6.6 0.1 3.1 3 0 0 3 3 3 0 FANCI solenoid 1 cap zf-C2H2 PF00096.21 KFO99302.1 - 5.3e-14 51.6 24.9 2.6e-06 27.4 1.9 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO99302.1 - 3.3e-13 49.2 8.2 2e-09 37.2 0.8 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO99302.1 - 2.1e-09 37.0 20.2 0.0014 18.8 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFO99302.1 - 0.012 15.7 3.3 2.2 8.5 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO99302.1 - 0.1 12.7 3.6 3.4 7.9 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFO99302.1 - 1.1 9.2 6.5 0.42 10.6 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger TIR PF01582.15 KFO99303.1 - 2.6e-35 120.8 0.1 4.5e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.1 KFO99303.1 - 1.3e-13 50.4 15.6 2.1e-07 30.5 1.4 4.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KFO99303.1 - 6e-13 48.0 23.2 5.6e-07 29.0 0.2 5.8 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFO99303.1 - 1.2e-11 43.3 7.6 0.077 13.1 0.0 6.7 5 2 2 7 7 7 4 Leucine Rich repeat TIR_2 PF13676.1 KFO99303.1 - 1e-10 41.6 0.0 2.9e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 TIR domain LRR_1 PF00560.28 KFO99303.1 - 7.8e-10 37.4 13.4 0.12 12.4 0.2 7.3 6 1 1 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 KFO99303.1 - 0.00019 21.0 16.1 0.63 10.4 0.1 7.1 7 0 0 7 7 7 2 Leucine rich repeat TIR PF01582.15 KFO99305.1 - 3.4e-35 120.5 0.1 7.3e-35 119.4 0.1 1.6 1 0 0 1 1 1 1 TIR domain LRR_8 PF13855.1 KFO99305.1 - 1.7e-13 50.0 18.1 2.6e-07 30.2 1.5 4.3 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 KFO99305.1 - 2.9e-13 49.0 29.6 5.8e-07 28.9 0.2 7.3 5 2 3 8 8 8 5 Leucine Rich repeats (2 copies) TIR_2 PF13676.1 KFO99305.1 - 1.7e-10 40.9 0.0 4.5e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 TIR domain LRR_6 PF13516.1 KFO99305.1 - 3e-09 35.9 17.5 0.11 12.6 0.0 8.6 8 1 1 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.28 KFO99305.1 - 1.3e-08 33.7 19.4 0.13 12.3 0.6 8.8 8 1 0 8 8 8 3 Leucine Rich Repeat LRRCT PF01463.19 KFO99305.1 - 0.0014 18.7 0.1 0.0067 16.6 0.0 2.3 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain LRR_7 PF13504.1 KFO99305.1 - 0.007 16.3 22.9 0.87 10.0 0.1 8.1 9 0 0 9 9 9 2 Leucine rich repeat TMEM156 PF15106.1 KFO99307.1 - 8.6e-79 263.9 15.3 9.8e-79 263.7 10.6 1.0 1 0 0 1 1 1 1 TMEM156 protein family Renin_r PF07850.9 KFO99307.1 - 0.038 14.3 0.4 0.095 13.0 0.3 1.7 1 0 0 1 1 1 0 Renin receptor-like protein Clathrin PF00637.15 KFO99308.1 - 3e-11 43.0 4.6 0.00016 21.2 0.1 5.2 3 1 1 5 5 5 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 KFO99308.1 - 1.7e-07 30.3 11.3 0.0074 15.1 0.2 4.4 5 0 0 5 5 5 3 Coatomer WD associated region WD40 PF00400.27 KFO99308.1 - 5.3e-07 29.2 7.1 0.083 12.8 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat TPR_11 PF13414.1 KFO99308.1 - 3.4e-06 26.6 13.4 0.02 14.5 0.0 5.3 5 1 1 6 6 6 2 TPR repeat Apc3 PF12895.2 KFO99308.1 - 3.8e-06 26.9 4.1 4.5 7.4 0.0 5.7 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFO99308.1 - 4.8e-06 26.4 5.8 0.03 14.2 0.2 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat IKI3 PF04762.7 KFO99308.1 - 0.0001 20.2 3.4 0.023 12.5 0.1 3.1 2 1 0 3 3 3 2 IKI3 family Apc4_WD40 PF12894.2 KFO99308.1 - 0.00043 19.7 0.0 0.24 10.9 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.1 KFO99308.1 - 0.0006 20.2 4.8 43 5.1 0.1 7.7 8 2 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFO99308.1 - 0.00095 19.4 3.5 24 5.3 0.1 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat eIF2A PF08662.6 KFO99308.1 - 0.0072 16.0 0.4 0.052 13.2 0.1 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.12 KFO99308.1 - 0.0083 15.9 13.9 12 6.1 0.2 7.1 7 1 0 7 7 6 0 Tetratricopeptide repeat DZR PF12773.2 KFO99308.1 - 0.012 15.3 11.2 0.088 12.6 7.4 2.3 1 1 0 1 1 1 0 Double zinc ribbon TPR_8 PF13181.1 KFO99308.1 - 0.05 13.3 10.5 13 5.8 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat SdiA-regulated PF06977.6 KFO99308.1 - 0.051 12.5 0.0 10 4.9 0.0 3.0 3 0 0 3 3 3 0 SdiA-regulated TPR_7 PF13176.1 KFO99308.1 - 1.6 8.7 13.0 26 4.9 0.1 6.4 6 1 1 7 7 6 0 Tetratricopeptide repeat RFC1 PF08519.7 KFO99309.1 - 8.2e-59 197.8 0.0 2.5e-58 196.2 0.0 1.9 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KFO99309.1 - 4e-16 58.9 0.0 9.5e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KFO99309.1 - 2.8e-15 56.6 0.0 6.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFO99309.1 - 1.9e-07 31.9 0.0 9.7e-07 29.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain PTCB-BRCT PF12738.2 KFO99309.1 - 9.3e-06 25.4 0.1 2.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain AAA_14 PF13173.1 KFO99309.1 - 8.2e-05 22.5 0.1 0.00036 20.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFO99309.1 - 0.00019 21.6 0.0 0.00071 19.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFO99309.1 - 0.00053 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KFO99309.1 - 0.00054 20.1 0.0 0.0027 17.8 0.0 2.3 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KFO99309.1 - 0.00056 20.2 0.1 0.0024 18.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFO99309.1 - 0.00091 19.1 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFO99309.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFO99309.1 - 0.018 15.0 0.1 0.061 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain SRCR PF00530.13 KFO99309.1 - 0.055 13.8 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain AAA_19 PF13245.1 KFO99309.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Glyco_hydro_1 PF00232.13 KFO99310.1 - 7.4e-166 551.8 15.4 1.6e-83 280.4 0.5 3.1 2 1 1 3 3 3 3 Glycosyl hydrolase family 1 Y_phosphatase3C PF13348.1 KFO99310.1 - 0.00041 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region DUF3511 PF12023.3 KFO99310.1 - 0.074 12.3 0.1 3.7 6.9 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) Ribosomal_L6 PF00347.18 KFO99311.1 - 4.5e-35 119.9 2.1 1e-16 61.1 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Radical_SAM PF04055.16 KFO99312.1 - 6.9e-18 65.3 0.0 1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UDPG_MGDP_dh_N PF03721.9 KFO99313.1 - 1.8e-44 151.3 0.1 3e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KFO99313.1 - 4e-37 126.5 0.0 2.9e-35 120.6 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KFO99313.1 - 6.8e-22 77.5 0.0 5.5e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Ldh_1_N PF00056.18 KFO99313.1 - 0.0082 15.9 0.1 4.6 7.0 0.0 3.7 2 2 2 4 4 4 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFO99313.1 - 0.025 14.8 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KFO99313.1 - 0.047 13.4 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KFO99313.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KFO99313.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2615 PF11027.3 KFO99314.1 - 4.1e-43 145.5 0.0 4.5e-43 145.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) UQ_con PF00179.21 KFO99315.1 - 1e-41 141.6 0.0 1.3e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 KFO99315.1 - 6.8e-09 35.3 0.0 1.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.1 KFO99315.1 - 1.6e-07 31.1 0.0 3.2e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFO99315.1 - 0.0016 18.2 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFO99315.1 - 0.026 14.2 0.1 0.056 13.1 0.0 1.5 1 1 0 1 1 1 0 UEV domain UBA_3 PF09288.5 KFO99315.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain HEAT_2 PF13646.1 KFO99316.1 - 4e-05 23.7 2.8 1.3 9.3 0.0 6.0 6 1 0 6 6 6 2 HEAT repeats HEAT PF02985.17 KFO99316.1 - 0.00049 19.9 4.0 42 4.5 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 KFO99316.1 - 0.34 11.4 4.6 73 4.0 0.0 5.5 6 0 0 6 6 6 0 HEAT-like repeat Ras PF00071.17 KFO99317.1 - 7.7e-45 152.1 0.0 9e-45 151.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO99317.1 - 7.9e-20 71.5 0.0 1.1e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO99317.1 - 5.7e-06 25.6 0.0 7.6e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFO99317.1 - 0.0031 17.4 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 KFO99317.1 - 0.02 14.5 0.1 0.049 13.3 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFO99317.1 - 0.057 12.8 0.0 0.61 9.5 0.0 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KFO99317.1 - 0.089 11.9 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Neur_chan_LBD PF02931.18 KFO99320.1 - 8.8e-67 224.4 2.4 1.2e-66 224.0 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFO99320.1 - 9e-43 146.8 0.2 1.2e-42 146.4 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region L1R_F9L PF02442.12 KFO99320.1 - 0.073 12.5 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses RRM_1 PF00076.17 KFO99321.1 - 6.2e-39 131.4 0.6 2e-15 56.1 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO99321.1 - 7e-28 96.4 0.5 5.7e-09 35.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO99321.1 - 1.6e-15 56.6 0.3 9.3e-06 25.4 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFO99321.1 - 0.0076 15.9 0.1 0.21 11.3 0.0 2.8 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 KFO99321.1 - 0.061 13.1 0.5 2 8.2 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Spo7_2_N PF15407.1 KFO99321.1 - 0.18 11.2 0.0 25 4.4 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 Nol1_Nop2_Fmu PF01189.12 KFO99322.1 - 0.0069 15.7 0.1 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family Peptidase_C12 PF01088.16 KFO99323.1 - 3.5e-63 212.6 0.4 3.9e-63 212.4 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 LIM PF00412.17 KFO99324.1 - 2.5e-07 30.6 0.4 6.2e-07 29.3 0.3 1.7 1 0 0 1 1 1 1 LIM domain Homeobox PF00046.24 KFO99325.1 - 4.5e-14 51.7 0.5 6.9e-14 51.2 0.3 1.3 1 0 0 1 1 1 1 Homeobox domain UPF0121 PF03661.8 KFO99326.1 - 2.1e-116 387.4 17.0 2.4e-116 387.2 11.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Cation_efflux PF01545.16 KFO99327.1 - 5.4e-42 143.8 1.4 5.4e-42 143.8 1.0 1.4 2 0 0 2 2 2 1 Cation efflux family RapA_C PF12137.3 KFO99327.1 - 0.00022 20.1 0.6 0.00031 19.7 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal DUF1319 PF07028.6 KFO99327.1 - 0.025 14.7 0.4 0.051 13.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Ion_trans_N PF08412.5 KFO99327.1 - 0.069 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal IF3_C PF00707.17 KFO99327.1 - 0.16 11.7 1.5 2.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain BEN PF10523.4 KFO99328.1 - 1.9e-10 40.6 0.0 4.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 BEN domain Leu_zip PF15294.1 KFO99328.1 - 0.0028 16.8 2.7 0.011 14.8 0.1 2.1 2 0 0 2 2 2 1 Leucine zipper bZIP_1 PF00170.16 KFO99328.1 - 0.0054 16.6 0.1 0.014 15.3 0.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor Cep57_CLD_2 PF14197.1 KFO99328.1 - 0.015 15.1 0.3 0.089 12.7 0.1 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Uds1 PF15456.1 KFO99328.1 - 0.03 14.3 0.6 0.11 12.4 0.4 1.9 1 1 0 1 1 1 0 Up-regulated During Septation NYD-SP28_assoc PF14775.1 KFO99328.1 - 0.031 13.9 1.6 0.075 12.7 1.1 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 KFO99328.1 - 0.043 13.6 3.8 0.1 12.4 2.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Thioredoxin_2 PF13098.1 KFO99328.1 - 0.05 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Shugoshin_N PF07558.6 KFO99328.1 - 0.097 12.3 1.5 0.2 11.3 1.0 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region zf-C4pol PF14260.1 KFO99328.1 - 2.3 8.2 6.6 0.43 10.6 0.8 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Shisa PF13908.1 KFO99329.1 - 6.1e-14 52.5 1.2 8.5e-14 52.1 0.8 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3446 PF11928.3 KFO99329.1 - 0.26 11.4 5.8 0.49 10.6 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) E1-E2_ATPase PF00122.15 KFO99330.1 - 3.6e-19 68.7 0.0 6.8e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFO99330.1 - 5.3e-17 62.6 0.0 1.1e-16 61.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFO99330.1 - 4.5e-12 46.8 0.0 7.5e-11 42.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFO99330.1 - 6.3e-09 35.6 0.0 2.3e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFO99330.1 - 0.00025 20.7 0.3 0.009 15.6 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glutaredoxin PF00462.19 KFO99331.1 - 6.8e-10 38.7 0.1 6.1e-09 35.7 0.1 2.3 2 0 0 2 2 2 1 Glutaredoxin SH3BGR PF04908.10 KFO99331.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Zn-ribbon_8 PF09723.5 KFO99331.1 - 0.14 12.1 8.4 0.68 9.9 0.1 2.8 2 1 0 2 2 2 0 Zinc ribbon domain DnaJ_CXXCXGXG PF00684.14 KFO99331.1 - 0.9 9.6 14.5 17 5.5 0.1 2.6 1 1 1 2 2 2 0 DnaJ central domain Yip1 PF04893.12 KFO99332.1 - 9e-06 25.2 12.5 1.5e-05 24.5 8.7 1.5 1 0 0 1 1 1 1 Yip1 domain FMN_dh PF01070.13 KFO99332.1 - 0.17 10.6 0.1 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase GTP_EFTU PF00009.22 KFO99333.1 - 5.7e-52 175.8 0.2 8.2e-52 175.3 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KFO99333.1 - 3e-46 155.7 0.7 3e-46 155.7 0.5 2.2 3 0 0 3 3 3 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KFO99333.1 - 2e-19 69.2 0.0 8.3e-19 67.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KFO99333.1 - 7.5e-07 29.1 0.1 1.5e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KFO99333.1 - 1.4e-06 27.7 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 KFO99333.1 - 2.7e-06 27.1 0.0 9.5e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KFO99333.1 - 2.9e-06 27.3 0.2 7.3e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 KFO99333.1 - 0.0021 17.2 0.1 0.0061 15.7 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFO99333.1 - 0.033 14.6 0.0 0.07 13.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 KFO99333.1 - 0.05 12.6 0.8 0.16 10.9 0.0 2.0 2 0 0 2 2 2 0 Septin Glucosamine_iso PF01182.15 KFO99334.1 - 1.5e-23 83.6 0.0 2.1e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF4130 PF13566.1 KFO99334.1 - 0.12 11.9 0.5 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4130 Neur_chan_memb PF02932.11 KFO99335.1 - 9.5e-48 163.1 3.8 2.5e-41 142.1 0.5 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFO99335.1 - 1.6e-38 132.0 1.7 2.1e-38 131.6 1.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 KFO99336.1 - 5.5e-52 176.0 0.0 7.8e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFO99336.1 - 3.7e-45 154.6 9.4 2.7e-36 125.6 4.6 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 KFO99337.1 - 1e-52 179.4 2.8 2e-52 178.4 1.9 1.5 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFO99337.1 - 1.5e-44 151.7 0.0 2.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF4396 PF14342.1 KFO99337.1 - 0.7 9.9 8.6 0.88 9.6 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) HCaRG PF07258.9 KFO99338.1 - 1.8e-30 105.8 0.5 2e-30 105.6 0.3 1.0 1 0 0 1 1 1 1 HCaRG protein MgtE_N PF03448.12 KFO99338.1 - 0.0052 17.0 0.3 0.067 13.5 0.0 2.2 2 0 0 2 2 2 1 MgtE intracellular N domain DUF3117 PF11314.3 KFO99338.1 - 2.3 7.7 4.1 1.1 8.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3117) DUF1542 PF07564.6 KFO99338.1 - 3 7.9 8.3 0.48 10.4 2.1 2.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) E1-E2_ATPase PF00122.15 KFO99339.1 - 2.1e-17 62.9 0.0 5.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFO99339.1 - 1e-15 58.7 0.0 3.3e-11 44.0 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFO99339.1 - 5.7e-15 55.9 0.0 3.8e-14 53.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFO99339.1 - 1.1e-09 38.1 0.0 3.3e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFO99339.1 - 0.0041 16.7 0.1 0.0041 16.7 0.1 2.5 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFO99339.1 - 0.016 15.4 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Trypsin PF00089.21 KFO99340.1 - 1e-62 211.5 0.1 2.2e-62 210.5 0.0 1.6 1 0 0 1 1 1 1 Trypsin Ldl_recept_a PF00057.13 KFO99340.1 - 1.6e-60 200.6 141.3 1e-10 41.3 5.3 10.0 9 0 0 9 9 9 7 Low-density lipoprotein receptor domain class A Fz PF01392.17 KFO99340.1 - 4.2e-51 172.1 18.6 4.5e-31 107.6 4.7 5.8 4 2 1 5 5 5 2 Fz domain STE3 PF02076.10 KFO99340.1 - 0.033 13.2 3.4 0.99 8.4 0.1 2.5 3 0 0 3 3 3 0 Pheromone A receptor zf-NF-X1 PF01422.12 KFO99341.1 - 1.8e-11 43.7 125.6 1.2e-05 25.0 10.7 18.6 19 0 0 19 19 19 12 NF-X1 type zinc finger Ion_trans PF00520.26 KFO99342.1 - 1.2e-18 67.1 3.6 1.9e-18 66.4 2.5 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 KFO99342.1 - 3.4e-17 62.0 0.0 6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HrpB7 PF09486.5 KFO99342.1 - 0.041 13.7 0.3 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Ion_trans_2 PF07885.11 KFO99342.1 - 0.098 12.3 6.6 0.39 10.4 4.6 2.1 1 1 0 1 1 1 0 Ion channel Mg_trans_NIPA PF05653.9 KFO99343.1 - 5.6e-130 432.6 13.3 6.7e-130 432.4 9.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFO99343.1 - 8.7e-09 35.5 1.6 8.7e-09 35.5 1.1 3.3 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFO99343.1 - 5.1e-08 32.9 5.0 5.1e-08 32.9 3.5 4.3 3 1 1 4 4 4 1 EamA-like transporter family DUF1774 PF08611.5 KFO99343.1 - 0.67 10.1 4.4 1.2 9.3 0.0 3.1 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) Pkinase_Tyr PF07714.12 KFO99344.1 - 3e-94 314.9 0.2 3.6e-94 314.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO99344.1 - 5.1e-51 173.3 0.0 6.2e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFO99344.1 - 8.6e-05 22.2 1.0 0.00021 21.0 0.7 1.7 1 0 0 1 1 1 1 SH2 domain APH PF01636.18 KFO99344.1 - 0.039 13.6 0.0 0.095 12.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFO99344.1 - 0.072 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 KFO99345.1 - 6.4e-96 320.3 0.1 9e-96 319.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO99345.1 - 3e-49 167.5 0.0 4.7e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFO99345.1 - 7.5e-19 67.3 0.1 2e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFO99345.1 - 2.3e-16 58.9 0.3 9.2e-16 56.9 0.1 2.1 2 0 0 2 2 2 1 SH3 domain PH PF00169.24 KFO99345.1 - 2.4e-15 56.6 1.6 4.3e-12 46.1 0.2 2.4 2 0 0 2 2 2 2 PH domain BTK PF00779.14 KFO99345.1 - 2.5e-13 49.3 1.3 5.1e-13 48.3 0.9 1.5 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.1 KFO99345.1 - 2.2e-11 43.1 0.1 5.3e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO99345.1 - 9.3e-09 34.6 0.1 2.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFO99345.1 - 0.00017 21.7 1.0 0.0024 18.0 0.3 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Kinase-like PF14531.1 KFO99345.1 - 0.00071 18.6 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SLAIN PF15301.1 KFO99346.1 - 9.2e-136 452.8 37.9 1.1e-135 452.6 26.3 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family SBF PF01758.11 KFO99347.1 - 2e-22 79.5 14.7 2e-22 79.5 10.2 1.8 2 1 0 2 2 2 1 Sodium Bile acid symporter family DUF3392 PF11872.3 KFO99347.1 - 0.09 12.7 8.6 1.8 8.5 3.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) zf-3CxxC PF13695.1 KFO99348.1 - 4.1e-07 30.1 11.6 4.8e-07 29.9 8.1 1.1 1 0 0 1 1 1 1 Zinc-binding domain FYVE_2 PF02318.11 KFO99348.1 - 0.3 10.9 10.6 0.31 10.9 7.4 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.2 KFO99348.1 - 2.2 8.1 14.9 1.2e+02 2.6 10.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-TFIIB PF13453.1 KFO99348.1 - 2.8 7.2 10.4 3.6 6.8 1.2 2.2 1 1 1 2 2 2 0 Transcription factor zinc-finger Zn_clus PF00172.13 KFO99348.1 - 3.5 7.6 20.0 1.6 8.7 9.5 2.6 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ADK_lid PF05191.9 KFO99348.1 - 4.7 6.9 14.5 9.7 5.9 8.5 3.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid MOR2-PAG1_N PF14222.1 KFO99349.1 - 6.9e-169 563.0 3.9 1.2e-168 562.2 2.7 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KFO99349.1 - 6.7e-73 245.6 7.2 6.7e-73 245.6 5.0 3.2 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KFO99349.1 - 4.9e-40 137.0 12.8 5.6e-15 54.0 0.1 6.2 6 0 0 6 6 6 6 Cell morphogenesis central region OCIA PF07051.6 KFO99350.1 - 5.1e-30 103.1 0.0 9.4e-30 102.2 0.0 1.5 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) DUF566 PF04484.7 KFO99350.1 - 0.66 9.4 5.5 0.84 9.0 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) OCIA PF07051.6 KFO99351.1 - 1.1e-32 111.7 0.2 1.1e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) GLTT PF01744.15 KFO99351.1 - 0.033 13.5 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 GLTT repeat (6 copies) DUF3248 PF11609.3 KFO99351.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Cullin_binding PF03556.10 KFO99352.1 - 2.8e-33 114.5 1.3 4.6e-33 113.8 0.9 1.3 1 0 0 1 1 1 1 Cullin binding LRR_8 PF13855.1 KFO99353.1 - 2.8e-25 87.8 17.1 3e-15 55.7 1.0 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFO99353.1 - 1e-17 63.2 23.5 3.3e-06 26.5 0.4 4.4 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO99353.1 - 1.4e-12 45.7 25.7 0.1 12.6 0.5 8.3 8 1 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.1 KFO99353.1 - 2.8e-11 42.2 16.2 0.09 12.8 0.0 7.6 7 1 0 7 7 7 4 Leucine Rich repeat LRR_5 PF13306.1 KFO99353.1 - 4.7e-09 36.0 3.7 1.7e-08 34.2 0.3 2.3 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO99353.1 - 0.00031 20.4 18.7 6.7 7.3 0.2 7.3 8 0 0 8 8 8 2 Leucine rich repeat LRR_9 PF14580.1 KFO99353.1 - 0.0013 18.2 4.2 0.21 11.1 0.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat Orthopox_B11R PF07033.6 KFO99353.1 - 0.13 11.7 0.3 3.9 7.0 0.1 2.3 2 0 0 2 2 2 0 Orthopoxvirus B11R protein Sarcoglycan_1 PF04790.8 KFO99354.1 - 7.3e-75 251.5 0.4 8.6e-75 251.3 0.2 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein UCH PF00443.24 KFO99356.1 - 9.1e-69 231.5 9.3 1.1e-68 231.3 6.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO99356.1 - 4.1e-37 128.2 9.4 5e-37 127.9 6.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3510 PF12022.3 KFO99356.1 - 0.047 13.7 1.2 0.095 12.8 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Ras PF00071.17 KFO99357.1 - 8.6e-18 64.2 0.0 1.2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO99357.1 - 4.3e-10 40.1 0.0 8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF2819 PF10995.3 KFO99357.1 - 0.0096 14.7 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2819) MMR_HSR1 PF01926.18 KFO99357.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fip1 PF05182.8 KFO99359.1 - 4e-26 90.0 1.0 7.8e-26 89.0 0.7 1.5 1 0 0 1 1 1 1 Fip1 motif PRP38_assoc PF12871.2 KFO99359.1 - 9.5e-06 26.0 27.2 9.5e-06 26.0 18.8 4.5 3 1 1 4 4 4 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PDZ PF00595.19 KFO99360.1 - 7.1e-63 208.7 3.9 1.6e-17 63.4 0.0 4.2 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO99360.1 - 9.5e-19 67.0 0.1 0.001 18.8 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.20 KFO99360.1 - 1.5e-06 27.7 6.9 4.6e-06 26.1 4.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tricorn_PDZ PF14685.1 KFO99360.1 - 5.3e-06 26.1 0.1 3 7.6 0.0 4.3 4 0 0 4 4 4 2 Tricorn protease PDZ domain zf-RING_2 PF13639.1 KFO99360.1 - 7.3e-06 25.7 6.9 2.9e-05 23.7 4.8 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFO99360.1 - 8.4e-05 22.3 7.4 0.00029 20.6 5.1 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFO99360.1 - 0.00011 22.0 5.8 0.00044 20.2 4.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO99360.1 - 0.00012 21.7 5.2 0.00012 21.7 3.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFO99360.1 - 0.0022 17.6 2.6 0.0022 17.6 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFO99360.1 - 0.0059 16.6 3.5 0.03 14.4 2.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFO99360.1 - 0.031 13.9 5.3 0.094 12.4 3.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Yae1_N PF09811.4 KFO99361.1 - 2.2e-20 71.8 61.9 1.5e+04 -22.6 42.9 5.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Pkinase_Tyr PF07714.12 KFO99362.1 - 1.4e-104 348.7 0.0 2.1e-104 348.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO99362.1 - 5.6e-44 150.2 0.0 1.6e-30 106.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFO99362.1 - 1.2e-23 82.7 3.2 5.7e-09 35.7 0.0 5.8 5 1 1 6 6 6 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99362.1 - 4.4e-20 71.6 4.7 2.5e-05 24.3 0.0 5.3 4 1 1 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 KFO99362.1 - 8.1e-13 48.6 13.7 8.9e-06 26.1 0.1 5.3 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 KFO99362.1 - 6e-06 26.1 12.2 0.12 12.3 0.1 6.1 6 2 0 6 6 6 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO99362.1 - 0.0081 16.0 0.2 7 6.6 0.0 2.9 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFO99362.1 - 0.021 14.9 9.9 0.12 12.5 0.1 4.7 5 0 0 5 5 5 0 Immunoglobulin domain APH PF01636.18 KFO99362.1 - 0.23 11.1 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KFO99363.1 - 7.8e-103 343.0 0.0 1e-102 342.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO99363.1 - 4.5e-46 157.1 0.0 4.5e-33 114.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFO99363.1 - 1.1e-23 82.9 0.1 4.4e-15 55.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99363.1 - 3.7e-22 78.2 0.9 8.9e-09 35.3 0.0 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFO99363.1 - 1.6e-16 60.5 0.5 1.4e-08 35.0 0.0 3.6 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFO99363.1 - 2.1e-12 46.9 0.0 9.3e-09 35.2 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFO99363.1 - 1.4e-06 28.1 0.1 0.099 12.5 0.0 3.5 2 2 1 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO99363.1 - 9.6e-05 22.2 0.1 0.0005 19.9 0.0 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.1 KFO99363.1 - 0.096 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Steroid_dh PF02544.11 KFO99364.1 - 3.1e-22 78.9 6.8 4e-22 78.5 4.0 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase FB_lectin PF07367.6 KFO99364.1 - 0.0035 16.9 0.1 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal fruit body lectin HXXEE PF13787.1 KFO99364.1 - 0.35 11.2 0.1 0.35 11.2 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function with HXXEE motif UPF0016 PF01169.14 KFO99365.1 - 3.9e-43 145.4 20.3 3.7e-24 84.6 2.8 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Med9 PF07544.8 KFO99365.1 - 0.25 11.1 1.9 0.41 10.4 1.3 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 KFO99365.1 - 0.42 10.1 0.0 0.42 10.1 0.0 2.5 3 0 0 3 3 3 0 IncA protein NMU PF02070.10 KFO99366.1 - 2.7e-09 36.3 1.4 2.7e-09 36.3 1.0 2.1 2 0 0 2 2 2 1 Neuromedin U Sec3_C PF09763.4 KFO99367.1 - 6.9e-214 711.9 27.0 8.8e-214 711.6 18.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KFO99367.1 - 5.5e-29 99.8 2.1 1.8e-28 98.2 1.4 1.9 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH FlaC_arch PF05377.6 KFO99367.1 - 0.18 11.7 3.8 2.9 7.8 1.0 3.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GATase_2 PF00310.16 KFO99368.1 - 5.1e-25 87.9 0.0 2.9e-24 85.4 0.0 2.0 1 1 1 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFO99368.1 - 5.8e-17 61.9 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFO99368.1 - 1.9e-15 56.6 0.0 3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KFO99368.1 - 1.1e-12 47.7 0.0 2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KFO99368.1 - 1.4e-07 30.4 0.0 2.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Myb_DNA-bind_4 PF13837.1 KFO99369.1 - 2e-20 72.6 1.4 2.7e-20 72.2 1.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 KFO99369.1 - 0.00049 19.9 2.9 0.0011 18.7 2.0 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 KFO99369.1 - 0.0034 17.9 1.4 0.0048 17.5 1.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFO99369.1 - 0.012 15.7 1.8 0.023 14.8 1.2 1.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain SAICAR_synt PF01259.13 KFO99370.1 - 3.7e-83 278.4 0.1 4.7e-83 278.1 0.1 1.1 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.15 KFO99370.1 - 8.6e-36 122.4 0.0 1.6e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 AIR carboxylase LON PF02190.11 KFO99371.1 - 5e-27 94.9 0.0 9.5e-27 94.0 0.0 1.5 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KFO99371.1 - 2.9e-09 36.8 13.4 8e-09 35.3 9.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO99371.1 - 1.8e-08 33.9 9.5 3.5e-08 33.0 6.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO99371.1 - 2.3e-08 33.7 13.5 5.6e-08 32.4 9.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFO99371.1 - 1.9e-07 30.6 12.4 5.5e-07 29.1 8.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO99371.1 - 3e-06 26.8 12.4 7.6e-06 25.5 8.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFO99371.1 - 1.8e-05 24.4 10.1 7.3e-05 22.5 7.1 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING TPR_2 PF07719.12 KFO99371.1 - 2.8e-05 23.7 0.0 0.038 13.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFO99371.1 - 9.1e-05 22.0 0.0 0.00024 20.6 0.0 1.7 2 0 0 2 2 1 1 TPR repeat zf-RING_UBOX PF13445.1 KFO99371.1 - 0.0003 20.4 6.7 0.00042 19.9 2.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger U-box PF04564.10 KFO99371.1 - 0.001 18.9 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.23 KFO99371.1 - 0.0063 16.0 0.1 7 6.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.3 KFO99371.1 - 0.0065 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 zf-RING_6 PF14835.1 KFO99371.1 - 0.011 15.5 6.0 0.025 14.3 4.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KFO99371.1 - 0.015 15.4 4.5 0.039 14.0 3.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KFO99371.1 - 0.056 13.0 9.3 0.15 11.6 6.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_14 PF13428.1 KFO99371.1 - 0.1 13.2 0.0 5.9 7.8 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Baculo_IE-1 PF05290.6 KFO99371.1 - 1.4 8.6 5.7 1.5 8.5 2.9 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Methyltransf_11 PF08241.7 KFO99372.1 - 4.7e-15 55.8 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO99372.1 - 1.1e-07 31.6 0.0 3e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO99372.1 - 8e-07 28.7 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO99372.1 - 2.3e-06 27.9 0.0 8.6e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFO99372.1 - 2.3e-05 24.6 0.0 7.3e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFO99372.1 - 3.8e-05 22.9 0.0 0.00014 21.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KFO99372.1 - 4.4e-05 23.2 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.15 KFO99372.1 - 0.00028 20.0 0.1 0.0066 15.5 0.1 2.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KFO99372.1 - 0.0068 16.9 0.0 0.03 14.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFO99372.1 - 0.027 13.1 0.0 0.28 9.8 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.14 KFO99372.1 - 0.17 11.3 0.1 0.86 9.0 0.0 1.9 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) START PF01852.14 KFO99373.1 - 1.7e-46 158.1 0.0 3.5e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 START domain RhoGAP PF00620.22 KFO99373.1 - 2e-41 141.1 0.6 7.4e-41 139.2 0.6 1.9 2 0 0 2 2 2 1 RhoGAP domain Pox_A28 PF04584.9 KFO99374.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A28 family Sarcoglycan_1 PF04790.8 KFO99375.1 - 1.5e-104 348.8 0.0 1.8e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 KFO99375.1 - 0.0001 21.9 0.1 0.025 14.1 0.0 2.6 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) DUF2208 PF09973.4 KFO99375.1 - 0.025 13.8 0.1 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) OST3_OST6 PF04756.8 KFO99376.1 - 8.8e-53 178.1 0.1 1.3e-52 177.5 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KFO99376.1 - 7.1e-06 25.6 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4131 PF13567.1 KFO99376.1 - 0.0039 16.6 3.3 0.072 12.4 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4131) YhhN PF07947.9 KFO99376.1 - 0.047 13.0 3.0 0.16 11.2 2.0 1.8 1 1 0 1 1 1 0 YhhN-like protein FGF PF00167.13 KFO99377.1 - 2.8e-31 107.8 0.0 3.2e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor EF-hand_8 PF13833.1 KFO99378.1 - 2.9e-19 68.4 12.6 2.3e-11 43.1 0.0 6.2 5 2 1 6 6 6 2 EF-hand domain pair EF-hand_6 PF13405.1 KFO99378.1 - 6.5e-10 38.0 12.9 0.00038 20.0 0.3 6.7 8 0 0 8 8 8 2 EF-hand domain EF-hand_7 PF13499.1 KFO99378.1 - 8.5e-10 38.6 9.2 9.7e-05 22.4 0.2 5.3 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 KFO99378.1 - 9.6e-10 37.0 19.8 6.5e-05 21.9 0.4 6.9 8 0 0 8 8 8 2 EF hand EF-hand_4 PF12763.2 KFO99378.1 - 0.0086 15.7 1.1 0.12 12.0 0.1 3.1 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand HGD-D PF06050.8 KFO99378.1 - 0.1 11.3 0.2 0.88 8.3 0.0 2.2 2 1 0 3 3 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component EF-hand_5 PF13202.1 KFO99378.1 - 1.3 8.4 14.8 2.6 7.5 0.1 5.7 8 0 0 8 8 8 0 EF hand zf-DHHC PF01529.15 KFO99379.1 - 1.5e-41 141.7 8.0 2.5e-41 140.9 5.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Spt4 PF06093.8 KFO99379.1 - 1.1 9.1 6.8 2.1 8.2 4.7 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger CAF1 PF04857.15 KFO99380.1 - 1.4e-70 237.6 0.1 2.2e-70 237.0 0.1 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease Mod_r PF07200.8 KFO99381.1 - 1.1e-47 161.6 16.1 1.4e-47 161.3 11.2 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.8 KFO99381.1 - 0.0029 17.2 0.8 0.0029 17.2 0.5 2.9 4 0 0 4 4 4 1 UEV domain SWI-SNF_Ssr4 PF08549.5 KFO99381.1 - 0.023 13.0 1.7 0.91 7.7 0.0 2.2 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) Phage_Gp23 PF10669.4 KFO99381.1 - 0.16 12.1 1.5 5.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DivIVA PF05103.8 KFO99381.1 - 3.2 7.8 9.2 5.2 7.1 5.5 2.0 1 1 0 1 1 1 0 DivIVA protein Myotub-related PF06602.9 KFO99382.1 - 5.1e-144 479.4 0.1 6.7e-144 479.0 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 KFO99382.1 - 0.00091 18.8 0.0 0.0031 17.0 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO99382.1 - 0.0015 17.9 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFO99382.1 - 0.0046 17.2 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family GRAM PF02893.15 KFO99382.1 - 0.075 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Vps36_ESCRT-II PF11605.3 KFO99382.1 - 0.094 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AA_permease_2 PF13520.1 KFO99383.1 - 3.4e-54 184.0 26.9 3.4e-54 184.0 18.7 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFO99383.1 - 2.8e-36 124.8 25.2 2.8e-36 124.8 17.5 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 KFO99383.1 - 1.4e-24 85.6 6.5 1.4e-24 85.6 4.5 3.9 4 0 0 4 4 4 1 C-terminus of AA_permease I-set PF07679.11 KFO99384.1 - 1.7e-14 53.4 0.2 1.3e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99384.1 - 9.3e-12 44.9 2.2 6.8e-05 22.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFO99384.1 - 3.2e-09 37.1 1.0 0.0039 17.6 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFO99384.1 - 3.6e-08 33.4 1.0 0.0023 18.0 0.0 4.6 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFO99384.1 - 0.0016 18.3 3.2 1.5 8.7 0.5 3.7 2 2 0 2 2 2 2 Immunoglobulin V-set domain Tetraspannin PF00335.15 KFO99386.1 - 0.0084 15.3 1.1 0.0084 15.3 0.8 1.1 1 0 0 1 1 1 1 Tetraspanin family Fibrinogen_C PF00147.13 KFO99387.1 - 4.9e-80 268.5 14.3 6.1e-80 268.2 9.9 1.1 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain TFIIE_alpha PF02002.12 KFO99389.1 - 3.3e-27 94.0 1.0 7.4e-27 92.9 0.7 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 KFO99389.1 - 1.4e-16 60.2 0.8 1.4e-16 60.2 0.5 2.0 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 KFO99389.1 - 1.1e-06 27.8 0.6 2.4e-06 26.7 0.4 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 KFO99389.1 - 0.034 13.8 0.7 0.072 12.7 0.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Elf1 PF05129.8 KFO99389.1 - 0.12 12.1 2.1 0.41 10.3 1.4 1.9 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like PyrI_C PF02748.10 KFO99389.1 - 0.13 11.6 3.7 0.17 11.3 1.5 2.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 KFO99389.1 - 0.17 12.0 1.5 17 5.6 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KFO99389.1 - 0.32 10.9 2.5 12 5.9 0.3 2.5 2 0 0 2 2 2 0 Zinc ribbon domain CBAH PF02275.13 KFO99390.1 - 2.8e-38 132.1 0.1 2.7e-34 119.0 0.0 2.1 1 1 1 2 2 2 2 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.1 KFO99390.1 - 1.6e-34 118.1 0.0 3.4e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase FRG1 PF06229.7 KFO99391.1 - 1.1e-81 272.9 1.0 1.1e-81 272.9 0.7 1.5 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 KFO99391.1 - 1.8e-08 34.4 0.0 8.7e-08 32.2 0.0 2.0 1 1 0 2 2 2 1 Fascin domain DUF569 PF04601.8 KFO99391.1 - 0.00025 20.4 0.1 0.0021 17.4 0.0 2.7 1 1 0 2 2 2 1 Protein of unknown function (DUF569) Cadherin PF00028.12 KFO99394.1 - 0 1665.7 101.0 7e-24 83.8 0.2 34.3 34 0 0 34 34 34 34 Cadherin domain Laminin_G_2 PF02210.19 KFO99394.1 - 6.6e-25 87.6 0.4 2.6e-24 85.6 0.3 2.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFO99394.1 - 5.8e-19 68.3 0.0 2.5e-18 66.3 0.0 2.2 1 0 0 1 1 1 1 Laminin G domain Cadherin_2 PF08266.7 KFO99394.1 - 6.7e-15 54.4 0.1 5.8 6.5 0.0 15.4 19 0 0 19 19 19 2 Cadherin-like EGF PF00008.22 KFO99394.1 - 2.3e-09 37.0 56.7 5.1e-05 23.1 4.4 4.8 5 0 0 5 5 5 3 EGF-like domain EGF_CA PF07645.10 KFO99394.1 - 4.9e-06 26.4 10.1 4.9e-06 26.4 7.0 4.5 4 0 0 4 4 4 1 Calcium-binding EGF domain Laminin_G_3 PF13385.1 KFO99394.1 - 4.5e-05 23.7 0.1 0.00017 21.9 0.1 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily NfeD PF01957.13 KFO99394.1 - 0.13 12.3 0.1 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding 7tm_1 PF00001.16 KFO99395.1 - 4.9e-51 173.3 23.9 6.8e-51 172.8 16.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFO99395.1 - 2.2e-08 33.5 22.7 3.3e-08 32.9 15.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 KFO99395.1 - 6e-08 32.1 20.1 8.1e-08 31.7 13.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4233 PF14017.1 KFO99395.1 - 3.3 7.6 24.9 2.4 8.1 0.8 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4233) Trypsin PF00089.21 KFO99396.1 - 6.9e-67 225.2 0.1 1e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.21 KFO99396.1 - 1.5e-30 104.7 31.9 9.6e-09 34.8 0.4 5.0 5 0 0 5 5 5 4 PAN domain PAN_4 PF14295.1 KFO99396.1 - 6.3e-19 67.4 21.1 2.3e-05 23.9 1.3 5.3 4 1 0 4 4 4 4 PAN domain DUF1986 PF09342.6 KFO99396.1 - 5.3e-05 22.6 0.0 5.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFO99396.1 - 0.018 14.9 0.0 0.058 13.3 0.0 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF3719 PF12516.3 KFO99397.1 - 3.9e-20 71.1 0.5 1.4e-19 69.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) SH3_1 PF00018.23 KFO99398.1 - 2e-43 145.5 0.4 1.6e-14 53.0 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.1 KFO99398.1 - 2.7e-42 142.0 1.4 2.1e-14 52.8 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KFO99398.1 - 3.4e-32 109.6 0.7 4.4e-15 54.8 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.11 KFO99398.1 - 1.4e-28 98.0 8.5 1.5e-28 97.9 1.5 2.6 2 0 0 2 2 2 1 Sorbin homologous domain PDZ PF00595.19 KFO99399.1 - 1.5e-16 60.3 0.0 3.7e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 KFO99399.1 - 1.7e-13 50.4 3.9 3.1e-13 49.5 2.7 1.4 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 KFO99399.1 - 0.00011 22.0 0.0 0.0003 20.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain DUF4586 PF15239.1 KFO99400.1 - 2.8e-111 371.8 8.8 3.3e-111 371.6 6.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Peptidase_C78 PF07910.8 KFO99401.1 - 1.3e-53 181.3 0.1 1.9e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Ank_2 PF12796.2 KFO99402.1 - 5.6e-10 39.4 0.1 7.2e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFO99402.1 - 1.8e-09 37.5 2.1 5.7e-07 29.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFO99402.1 - 7e-08 31.9 1.7 0.017 14.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFO99402.1 - 2.8e-06 27.6 0.2 0.012 16.0 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO99402.1 - 0.16 12.2 0.5 24 5.5 0.0 3.0 3 1 0 3 3 3 0 Ankyrin repeat Nexin_C PF08628.7 KFO99403.1 - 8e-33 112.9 1.7 1.7e-32 111.8 0.2 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PXA PF02194.10 KFO99403.1 - 1.4e-29 103.0 2.1 1.4e-29 103.0 1.5 3.8 3 1 0 3 3 3 1 PXA domain RGS PF00615.14 KFO99403.1 - 1.8e-20 73.2 0.9 1.8e-20 73.2 0.6 3.3 4 0 0 4 4 4 1 Regulator of G protein signaling domain PX PF00787.19 KFO99403.1 - 6.3e-19 67.8 0.1 4.3e-18 65.1 0.1 2.5 1 0 0 1 1 1 1 PX domain Isy1 PF06246.7 KFO99403.1 - 0.076 12.4 0.1 0.076 12.4 0.1 3.1 3 1 0 3 3 3 0 Isy1-like splicing family Mito_carr PF00153.22 KFO99404.1 - 1.2e-58 194.7 3.0 7.6e-23 80.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein HLH PF00010.21 KFO99405.1 - 1.2e-17 63.3 0.2 2e-17 62.5 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFO99405.1 - 1.3e-09 37.5 0.5 3.1e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 Hairy Orange RNA_pol_Rpb4 PF03874.11 KFO99405.1 - 0.019 14.9 0.4 0.87 9.6 0.3 2.1 1 1 0 1 1 1 0 RNA polymerase Rpb4 CENP-U PF13097.1 KFO99406.1 - 6.7e-38 130.3 13.1 6.7e-38 130.3 9.1 2.1 3 0 0 3 3 3 1 CENP-A nucleosome associated complex (NAC) subunit HisG PF01634.13 KFO99406.1 - 0.0044 16.6 0.7 0.0097 15.4 0.5 1.6 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Mt_ATP-synt_B PF05405.9 KFO99406.1 - 0.088 12.2 11.8 0.073 12.5 5.1 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Tup_N PF08581.5 KFO99406.1 - 0.52 10.5 11.0 1.3 9.2 5.6 2.6 1 1 1 2 2 2 0 Tup N-terminal Syntaxin-6_N PF09177.6 KFO99406.1 - 3.7 8.0 8.7 2 8.8 1.6 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 KFO99406.1 - 4.1 5.1 12.8 0.68 7.7 6.1 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL52 PF03121.10 KFO99407.1 - 8.1e-15 54.3 0.9 2.2e-14 52.9 0.0 2.1 3 0 0 3 3 3 1 Herpesviridae UL52/UL70 DNA primase DNA_primase_S PF01896.14 KFO99407.1 - 2.9e-07 30.4 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit IRF PF00605.12 KFO99408.1 - 6.7e-47 157.8 1.3 1.2e-46 157.0 0.9 1.4 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Heme_oxygenase PF01126.15 KFO99408.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Heme oxygenase Phosphodiest PF01663.17 KFO99409.1 - 9.5e-69 232.4 0.3 1.1e-68 232.2 0.2 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFO99409.1 - 0.012 14.8 0.1 0.019 14.1 0.0 1.5 1 1 0 1 1 1 0 Sulfatase PglZ PF08665.7 KFO99409.1 - 0.02 14.5 0.1 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 PglZ domain Metalloenzyme PF01676.13 KFO99409.1 - 0.12 11.7 0.1 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.12 KFO99409.1 - 0.16 10.3 0.0 0.24 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Stork_head PF10264.4 KFO99410.1 - 1.5e-38 130.8 0.1 4e-38 129.4 0.1 1.8 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain Gryzun PF07919.7 KFO99411.1 - 1.4e-113 380.1 0.5 1.8e-113 379.8 0.3 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KFO99411.1 - 3.9e-76 255.7 0.3 8.3e-76 254.7 0.2 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 KFO99411.1 - 2.6e-24 84.7 0.1 1.3e-23 82.5 0.0 2.1 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Prefoldin PF02996.12 KFO99411.1 - 0.048 13.3 0.1 0.22 11.1 0.1 2.2 1 0 0 1 1 1 0 Prefoldin subunit TRAPPC10 PF12584.3 KFO99411.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_11 PF13414.1 KFO99411.1 - 4.1 7.1 6.7 3.9 7.1 0.1 3.2 3 0 0 3 3 3 0 TPR repeat RWD PF05773.17 KFO99412.1 - 2.8e-14 52.9 0.1 6.8e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 RWD domain Inhibitor_I71 PF12628.2 KFO99412.1 - 0.004 16.8 0.5 0.005 16.5 0.3 1.1 1 0 0 1 1 1 1 Falstatin, cysteine peptidase inhibitor ING PF12998.2 KFO99413.1 - 4.8e-13 49.2 4.5 4.8e-13 49.2 3.1 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFO99413.1 - 2.9e-10 39.6 7.9 2.9e-10 39.6 5.5 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KFO99413.1 - 0.0086 15.3 3.4 0.023 14.0 2.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 KFO99413.1 - 0.011 15.6 6.7 0.31 11.0 3.9 2.6 2 0 0 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.1 KFO99413.1 - 0.22 11.6 6.6 0.049 13.7 1.7 2.1 2 1 0 2 2 2 0 PHD-like zinc-binding domain DDHD PF02862.12 KFO99413.1 - 2.6 7.7 6.3 3.6 7.3 4.4 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KFO99413.1 - 2.8 7.7 8.9 3.6 7.3 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3469 PF11952.3 KFO99414.1 - 2.5e-13 49.5 0.2 1e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3469) Ish1 PF10281.4 KFO99414.1 - 0.11 12.5 0.0 0.41 10.7 0.0 2.0 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Red1 PF07964.6 KFO99414.1 - 2 6.4 16.6 2.9 5.9 11.5 1.1 1 0 0 1 1 1 0 Rec10 / Red1 PMP22_Claudin PF00822.15 KFO99415.1 - 4.3e-24 85.0 0.8 5.1e-24 84.7 0.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO99415.1 - 1.2e-07 31.6 0.7 2e-07 30.8 0.3 1.5 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane PF01061.19 KFO99415.1 - 0.13 11.3 5.0 2.4 7.2 0.0 2.9 2 1 1 3 3 3 0 ABC-2 type transporter DUF4131 PF13567.1 KFO99415.1 - 2.7 7.3 5.5 15 4.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PMP22_Claudin PF00822.15 KFO99416.1 - 2.9e-12 46.5 0.1 3.3e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFO99416.1 - 3e-05 23.7 0.2 3.1e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction C2 PF00168.25 KFO99417.1 - 0.014 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 C2 domain dCMP_cyt_deam_1 PF00383.17 KFO99418.1 - 1.3e-28 98.6 0.1 1.8e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1293 PF06950.6 KFO99418.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) Ten_N PF06484.7 KFO99419.1 - 1.5e-47 162.4 13.5 2.4e-47 161.8 9.3 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.1 KFO99419.1 - 4.4e-32 109.5 2.0 6.2e-32 109.0 0.7 1.9 2 0 0 2 2 2 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin NHL PF01436.16 KFO99419.1 - 4.8e-13 48.3 3.1 0.0077 16.1 0.0 6.7 6 0 0 6 6 6 5 NHL repeat RHS_repeat PF05593.9 KFO99419.1 - 8.8e-11 41.6 37.0 0.0031 17.6 0.4 11.1 8 2 0 8 8 8 3 RHS Repeat EGF_2 PF07974.8 KFO99419.1 - 9.9e-10 38.4 181.2 0.0029 17.7 8.6 9.8 10 0 0 10 10 10 8 EGF-like domain hEGF PF12661.2 KFO99419.1 - 2e-06 27.5 88.0 0.094 12.8 1.8 9.4 8 0 0 8 8 8 6 Human growth factor-like EGF CarboxypepD_reg PF13620.1 KFO99419.1 - 0.0019 18.1 0.2 0.016 15.2 0.0 2.7 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Ten_N PF06484.7 KFO99420.1 - 3.1e-28 98.9 4.1 3.4e-28 98.8 2.9 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region Yae1_N PF09811.4 KFO99422.1 - 7.4e-08 31.7 20.1 0.0067 15.9 13.9 2.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Asparaginase_2 PF01112.13 KFO99423.1 - 1.4e-103 345.9 0.3 1.7e-103 345.7 0.2 1.0 1 0 0 1 1 1 1 Asparaginase zf-GRF PF06839.7 KFO99424.1 - 2.2e-35 120.3 27.9 6.8e-19 67.5 1.7 4.2 4 0 0 4 4 4 2 GRF zinc finger H2TH PF06831.9 KFO99424.1 - 3.2e-12 46.0 0.0 6.3e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 KFO99424.1 - 3.7e-06 27.2 0.0 8.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-RanBP PF00641.13 KFO99424.1 - 0.0019 17.2 3.1 0.0019 17.2 2.1 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others PDGF PF00341.12 KFO99426.1 - 5e-23 81.0 7.2 5e-23 81.0 5.0 3.2 3 0 0 3 3 3 1 PDGF/VEGF domain CXCXC PF03128.9 KFO99426.1 - 1.2e-09 37.6 48.6 0.007 16.4 2.6 8.8 8 0 0 8 8 8 5 CXCXC repeat RhoGEF PF00621.15 KFO99427.1 - 3.2e-34 118.3 7.3 3.2e-34 118.3 5.1 2.6 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.24 KFO99427.1 - 5.8e-07 29.6 0.0 3.6e-06 27.1 0.0 2.4 1 0 0 1 1 1 1 PH domain C1_1 PF00130.17 KFO99427.1 - 0.00015 21.4 7.1 0.00029 20.5 4.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFO99427.1 - 0.00037 20.1 6.0 0.00075 19.1 4.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PH_7 PF15408.1 KFO99427.1 - 0.006 16.4 0.1 0.016 15.0 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Kelch_1 PF01344.20 KFO99428.1 - 1e-55 185.0 0.9 6e-12 44.9 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFO99428.1 - 3.4e-35 118.7 2.4 7.4e-07 29.0 0.0 6.2 2 2 4 6 6 6 5 Kelch motif BACK PF07707.10 KFO99428.1 - 6.6e-33 112.6 3.1 8.4e-33 112.2 1.2 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFO99428.1 - 2.5e-29 100.7 0.4 1.7e-07 31.1 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KFO99428.1 - 1.3e-26 92.0 1.8 4.1e-09 36.0 0.0 5.9 4 2 1 5 5 5 5 Galactose oxidase, central domain BTB PF00651.26 KFO99428.1 - 4.8e-26 90.9 0.1 1.1e-25 89.7 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFO99428.1 - 1.7e-25 87.7 5.7 0.00016 21.3 0.0 6.3 5 1 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 KFO99428.1 - 4e-17 61.7 0.5 1.1e-08 34.8 0.0 5.8 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 KFO99428.1 - 0.0037 16.4 0.0 0.0091 15.1 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) DUF1668 PF07893.8 KFO99428.1 - 0.006 15.7 0.2 0.029 13.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) Root_cap PF06830.6 KFO99428.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Root cap Rax2 PF12768.2 KFO99428.1 - 0.061 12.5 0.2 3 6.9 0.0 2.6 2 1 0 3 3 3 0 Cortical protein marker for cell polarity Peptidase_M14 PF00246.19 KFO99429.1 - 1.2e-22 80.8 0.0 2.3e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Neurochondrin PF05536.6 KFO99429.1 - 0.0021 16.4 0.0 0.0047 15.3 0.0 1.5 2 0 0 2 2 2 1 Neurochondrin AstE_AspA PF04952.9 KFO99429.1 - 0.2 10.4 0.0 0.37 9.6 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Pkinase_Tyr PF07714.12 KFO99431.1 - 2.7e-91 305.2 0.1 5.6e-54 182.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFO99431.1 - 6.2e-47 159.9 0.0 2.6e-46 157.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFO99431.1 - 3.7e-13 49.1 0.0 9.9e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99431.1 - 8.1e-09 35.4 0.1 0.0037 17.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFO99431.1 - 0.00013 22.0 0.1 0.021 14.9 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFO99431.1 - 0.00052 20.4 0.4 0.5 10.9 0.1 2.7 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFO99431.1 - 0.0022 17.8 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain LRR_8 PF13855.1 KFO99431.1 - 0.032 13.9 0.5 0.093 12.4 0.4 1.8 1 0 0 1 1 1 0 Leucine rich repeat SKG6 PF08693.5 KFO99431.1 - 0.17 11.1 0.4 0.36 10.1 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MRP-L46 PF11788.3 KFO99432.1 - 7.5e-15 55.5 0.6 1.3e-14 54.7 0.4 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Ribosomal_S11 PF00411.14 KFO99433.1 - 1.9e-28 98.8 2.2 2.7e-28 98.3 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Malic_M PF03949.10 KFO99433.1 - 0.26 10.7 3.9 0.36 10.3 2.7 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Det1 PF09737.4 KFO99434.1 - 2.7e-178 592.8 0.7 3.3e-178 592.5 0.5 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 RNase_T PF00929.19 KFO99435.1 - 2.9e-30 105.7 0.0 4.5e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KFO99435.1 - 1.4e-05 24.6 0.0 3.5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease Xlink PF00193.12 KFO99436.1 - 1.4e-142 464.1 18.2 7.5e-38 128.5 0.7 5.1 5 0 0 5 5 5 4 Extracellular link domain Lectin_C PF00059.16 KFO99436.1 - 7.5e-22 77.9 17.7 2.1e-19 70.1 2.4 5.2 5 0 0 5 5 5 1 Lectin C-type domain Sushi PF00084.15 KFO99436.1 - 1.3e-09 38.2 1.6 3.7e-09 36.7 1.1 1.9 1 0 0 1 1 1 1 Sushi domain (SCR repeat) V-set PF07686.12 KFO99436.1 - 3.8e-09 36.4 0.0 1.2e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain EGF PF00008.22 KFO99436.1 - 4.2e-06 26.5 5.4 1.5e-05 24.8 3.7 2.1 1 0 0 1 1 1 1 EGF-like domain Toxin_42 PF15522.1 KFO99436.1 - 0.013 14.6 0.1 9 5.4 0.0 3.5 3 1 0 3 3 3 0 Putative toxin 42 Chordopox_A33R PF05966.7 KFO99436.1 - 0.02 13.6 5.4 0.84 8.3 0.2 4.1 4 0 0 4 4 4 0 Chordopoxvirus A33R protein EGF_CA PF07645.10 KFO99436.1 - 0.16 11.9 8.5 0.39 10.7 4.8 2.6 2 1 0 2 2 2 0 Calcium-binding EGF domain EGF_2 PF07974.8 KFO99436.1 - 4.6 7.5 6.3 17 5.6 4.3 2.1 1 0 0 1 1 1 0 EGF-like domain Xlink PF00193.12 KFO99437.1 - 3.6e-39 132.7 0.0 5.5e-31 106.4 0.0 2.3 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 KFO99437.1 - 2.6e-13 49.8 0.0 4.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFO99437.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99437.1 - 0.00018 21.5 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO99437.1 - 0.00046 20.2 0.0 0.0028 17.7 0.0 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.16 KFO99437.1 - 0.0069 17.0 0.3 1.3 9.6 0.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain Ig_3 PF13927.1 KFO99437.1 - 0.013 16.0 0.0 0.11 12.9 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin domain V-set_CD47 PF08204.6 KFO99437.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Abhydrolase_1 PF00561.15 KFO99438.1 - 1.4e-22 80.3 0.0 2.1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFO99438.1 - 3.7e-09 36.8 0.0 5.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFO99438.1 - 7.4e-07 29.0 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KFO99438.1 - 0.00094 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Cutinase DUF915 PF06028.6 KFO99438.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 KFO99438.1 - 0.029 13.9 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 KFO99438.1 - 0.067 12.4 0.1 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family VirJ PF06057.6 KFO99438.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) CRAL_TRIO PF00650.15 KFO99439.1 - 6e-38 129.8 0.1 9.7e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFO99439.1 - 4.6e-12 46.0 0.0 7.4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFO99439.1 - 2.7e-07 30.6 0.5 1.2e-06 28.5 0.3 2.3 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain FANCI_S4 PF14678.1 KFO99440.1 - 1.7e-101 338.6 5.3 1.7e-101 338.6 3.7 2.4 2 0 0 2 2 2 1 FANCI solenoid 4 FANCI_HD2 PF14680.1 KFO99440.1 - 2e-101 337.9 4.2 3e-101 337.4 1.6 2.3 2 0 0 2 2 2 1 FANCI helical domain 2 FANCI_S3 PF14677.1 KFO99440.1 - 9.8e-86 286.6 3.0 9.8e-86 286.6 2.1 2.8 4 0 0 4 4 4 1 FANCI solenoid 3 FANCI_S1 PF14675.1 KFO99440.1 - 2.6e-77 259.1 0.6 1.1e-76 257.0 0.4 2.2 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_S2 PF14676.1 KFO99440.1 - 6.7e-52 175.5 0.2 6.7e-52 175.5 0.1 3.9 4 0 0 4 4 4 1 FANCI solenoid 2 FANCI_HD1 PF14679.1 KFO99440.1 - 6.1e-32 109.2 0.3 2.6e-31 107.1 0.2 2.2 1 0 0 1 1 1 1 FANCI helical domain 1 FANCI_S1-cap PF14674.1 KFO99440.1 - 1.8e-25 88.7 0.9 9.2e-25 86.4 0.6 2.4 1 0 0 1 1 1 1 FANCI solenoid 1 cap DNA_pol_A PF00476.15 KFO99441.1 - 1.5e-122 408.9 0.0 2e-122 408.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 KFO99441.1 - 0.067 12.6 0.1 0.47 9.9 0.1 2.1 1 1 0 1 1 1 0 3'-5' exonuclease Ammonium_transp PF00909.16 KFO99442.1 - 1.4e-75 254.3 20.1 1.7e-75 254.0 13.9 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2985 PF11204.3 KFO99442.1 - 0.12 12.1 2.8 0.25 11.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) Treslin_N PF15292.1 KFO99443.1 - 2.3e-262 872.5 6.4 2.7e-262 872.3 4.4 1.0 1 0 0 1 1 1 1 Treslin N-terminus Kinesin PF00225.18 KFO99445.1 - 1.6e-78 263.7 0.0 1.6e-78 263.7 0.0 2.9 3 1 0 3 3 3 1 Kinesin motor domain Ras PF00071.17 KFO99446.1 - 1.5e-18 66.6 0.0 1.7e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO99446.1 - 4.7e-12 46.4 0.0 5.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFO99446.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family Perilipin PF03036.11 KFO99447.1 - 1.8e-54 185.0 0.5 2.1e-54 184.9 0.4 1.0 1 0 0 1 1 1 1 Perilipin family NPV_P10 PF05531.7 KFO99447.1 - 0.048 13.9 0.3 0.14 12.4 0.0 1.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PEX11 PF05648.9 KFO99448.1 - 8.8e-60 201.7 0.4 9.9e-60 201.5 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) UPF0258 PF06789.7 KFO99449.1 - 2.9e-78 261.4 2.2 6.7e-78 260.2 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0258) 5-FTHF_cyc-lig PF01812.15 KFO99450.1 - 3.5e-50 170.3 0.0 3.9e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Bcl-2 PF00452.14 KFO99451.1 - 4.6e-26 90.8 0.1 6.5e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family zf-A20 PF01754.11 KFO99452.1 - 8e-13 47.7 7.7 2.1e-12 46.3 5.3 1.8 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.11 KFO99452.1 - 1.6e-11 43.8 6.0 1.6e-11 43.8 4.2 2.2 3 0 0 3 3 3 1 AN1-like Zinc finger FAA_hydrolase PF01557.13 KFO99453.1 - 1.5e-51 174.9 0.0 2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KFO99453.1 - 5.2e-34 116.4 0.0 1.2e-33 115.2 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal PAS_11 PF14598.1 KFO99454.1 - 1.4e-24 86.1 0.2 8.8e-20 70.7 0.1 3.0 2 1 1 3 3 3 2 PAS domain PAS_3 PF08447.6 KFO99454.1 - 1.2e-23 83.0 0.0 2.3e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KFO99454.1 - 1.6e-23 82.6 0.0 8e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFO99454.1 - 7e-15 54.4 1.1 1.6e-14 53.2 0.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFO99454.1 - 2e-10 40.9 0.0 6e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KFO99454.1 - 3.5e-05 23.8 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_6 PF08348.6 KFO99454.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 YheO-like PAS domain Abhydrolase_5 PF12695.2 KFO99455.1 - 1.3e-29 102.7 0.0 2.1e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFO99455.1 - 9.2e-15 55.1 0.1 4.1e-12 46.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO99455.1 - 1.5e-07 31.2 0.0 0.014 14.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFO99455.1 - 4.3e-07 29.3 0.0 1.5e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KFO99455.1 - 9e-05 21.8 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.7 KFO99455.1 - 0.00057 19.6 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DUF818 PF05677.7 KFO99455.1 - 0.00099 17.9 0.1 0.0015 17.3 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 KFO99455.1 - 0.0061 16.0 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KFO99455.1 - 0.0071 15.8 0.0 0.031 13.7 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase RNA_ligase PF09414.5 KFO99455.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA ligase Abhydrolase_4 PF08386.5 KFO99455.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein G8 PF10162.4 KFO99456.1 - 6.9e-29 100.1 0.0 1.5e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 G8 domain Mucin2_WxxW PF13330.1 KFO99456.1 - 1.7e-12 47.6 1.3 2.9e-11 43.6 0.1 2.5 2 0 0 2 2 2 1 Mucin-2 protein WxxW repeating region Beta_helix PF13229.1 KFO99456.1 - 0.016 14.9 7.4 1.2 8.9 0.0 4.1 4 2 0 4 4 4 0 Right handed beta helix region DNA_pol3_delta PF06144.8 KFO99456.1 - 0.27 10.7 0.0 0.55 9.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Mesd PF10185.4 KFO99457.1 - 8.2e-69 230.3 0.6 1.1e-68 229.8 0.5 1.2 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor PSII_BNR PF14870.1 KFO99457.1 - 0.057 12.3 0.0 0.17 10.8 0.0 1.6 1 1 1 2 2 2 0 Photosynthesis system II assembly factor YCF48 U79_P34 PF03064.11 KFO99457.1 - 0.14 11.6 5.8 1.4 8.3 4.1 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF4448 PF14610.1 KFO99457.1 - 0.15 11.5 1.5 0.21 11.0 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) PDZ PF00595.19 KFO99460.1 - 5.7e-30 103.3 0.1 2.9e-18 65.7 0.1 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO99460.1 - 7.5e-08 32.1 0.0 0.0019 18.0 0.0 2.5 2 1 0 2 2 2 2 PDZ domain START PF01852.14 KFO99461.1 - 2.2e-17 63.0 0.0 2.5e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 START domain STOP PF05217.7 KFO99462.1 - 3.4e-41 141.3 24.5 1e-24 87.4 4.6 4.0 1 1 3 4 4 4 4 STOP protein TSP_1 PF00090.14 KFO99463.1 - 1.9e-53 178.3 160.7 2.7e-06 27.3 2.9 14.9 14 1 0 14 14 14 12 Thrombospondin type 1 domain I-set PF07679.11 KFO99463.1 - 4e-33 113.1 0.0 1.8e-14 53.3 0.0 4.0 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99463.1 - 1.1e-27 95.9 0.3 2.7e-11 43.4 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 KFO99463.1 - 5.3e-21 74.8 4.6 1.4e-08 35.1 0.1 4.9 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 KFO99463.1 - 4.8e-14 52.2 0.3 1.9e-05 24.7 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFO99463.1 - 3.2e-12 46.3 0.6 0.00067 19.5 0.0 4.7 4 1 0 4 4 4 2 Immunoglobulin V-set domain ADAM_spacer1 PF05986.9 KFO99463.1 - 0.0038 17.0 0.0 0.0084 15.9 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Filament PF00038.16 KFO99464.1 - 9.7e-73 245.3 60.3 1.6e-72 244.6 41.8 1.5 1 1 0 1 1 1 1 Intermediate filament protein LTD PF00932.14 KFO99464.1 - 4.2e-16 59.0 0.0 7.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Lamin Tail Domain DUF2937 PF11157.3 KFO99464.1 - 0.0056 16.0 2.5 0.0056 16.0 1.7 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF2937) Reo_sigmaC PF04582.7 KFO99464.1 - 8.8 5.3 12.0 0.7 9.0 3.3 2.3 1 1 2 4 4 4 0 Reovirus sigma C capsid protein BAR PF03114.13 KFO99465.1 - 2.8e-75 252.7 8.5 3.3e-75 252.5 5.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFO99465.1 - 8.7e-15 53.8 0.1 2.5e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFO99465.1 - 1.3e-14 53.4 0.1 2.3e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFO99465.1 - 1.2e-13 50.3 0.0 2.8e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 KFO99465.1 - 9.2e-08 31.3 4.9 4.2e-06 25.8 1.2 2.1 2 0 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking zf-C2H2_4 PF13894.1 KFO99466.1 - 1e-10 41.1 33.5 0.0085 16.3 1.0 7.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.2 KFO99466.1 - 4.5e-09 36.1 20.8 0.0023 18.0 0.1 5.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO99466.1 - 7.6e-06 25.9 16.3 0.061 13.4 1.0 4.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFO99466.1 - 4.7e-05 23.4 40.1 0.0039 17.4 1.3 7.4 6 1 0 6 6 6 4 Zinc finger, C2H2 type PWWP PF00855.12 KFO99467.1 - 8.2e-08 32.3 0.0 8.2e-08 32.3 0.0 2.1 2 1 0 2 2 2 1 PWWP domain Pox_Ag35 PF03286.9 KFO99467.1 - 0.61 9.5 12.6 0.93 8.9 8.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 KFO99467.1 - 1.8 7.3 12.8 2.2 7.0 8.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 KFO99467.1 - 5.2 5.4 9.2 6.6 5.1 6.4 1.1 1 0 0 1 1 1 0 Raftlin DUF2781 PF10914.3 KFO99468.1 - 7.9e-37 126.3 2.8 7.9e-37 126.3 1.9 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2781) DUF4131 PF13567.1 KFO99468.1 - 5.1 6.4 6.3 2.9 7.2 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PHR PF08005.7 KFO99469.1 - 2e-49 167.6 0.4 3e-49 167.0 0.3 1.3 1 0 0 1 1 1 1 PHR domain BACK PF07707.10 KFO99469.1 - 1.7e-09 37.4 0.2 3.2e-08 33.3 0.0 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFO99469.1 - 8.9e-07 28.8 0.3 2.1e-05 24.4 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain DUF167 PF02594.11 KFO99470.1 - 8.3e-19 67.2 0.5 9.8e-19 67.0 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 ALS_ss_C PF10369.4 KFO99470.1 - 0.037 13.7 0.1 0.088 12.5 0.0 1.6 1 1 0 1 1 1 0 Small subunit of acetolactate synthase RAM PF15320.1 KFO99471.1 - 4.8e-22 78.0 1.4 5.2e-22 77.8 0.9 1.0 1 0 0 1 1 1 1 mRNA cap methylation, RNMT-activating mini protein WH1 PF00568.18 KFO99472.1 - 3e-36 123.4 0.4 6.5e-36 122.4 0.3 1.5 1 0 0 1 1 1 1 WH1 domain DMPK_coil PF08826.5 KFO99472.1 - 1.1e-05 25.2 4.0 1.1e-05 25.2 2.8 3.8 2 1 1 3 3 3 1 DMPK coiled coil domain like Macoilin PF09726.4 KFO99472.1 - 1.4e-05 23.6 23.8 1.7e-05 23.3 16.5 1.1 1 0 0 1 1 1 1 Transmembrane protein CALCOCO1 PF07888.6 KFO99472.1 - 1.8e-05 23.2 27.6 1.8e-05 23.2 19.2 1.6 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.1 KFO99472.1 - 0.0011 18.2 42.5 0.01 15.0 14.2 3.5 1 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KFO99472.1 - 0.0014 17.8 11.7 0.0025 17.0 0.8 2.5 2 1 1 3 3 2 2 Reovirus sigma C capsid protein IncA PF04156.9 KFO99472.1 - 0.0018 17.8 49.5 0.0039 16.7 15.2 3.0 1 1 2 3 3 3 2 IncA protein DUF4201 PF13870.1 KFO99472.1 - 0.0025 17.2 7.1 0.0025 17.2 4.9 3.3 2 1 2 4 4 4 2 Domain of unknown function (DUF4201) MscS_porin PF12795.2 KFO99472.1 - 0.0037 16.6 20.3 0.0037 16.6 14.1 2.4 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Phage_GP20 PF06810.6 KFO99472.1 - 0.0098 15.3 11.4 0.0098 15.3 7.9 3.6 2 1 2 4 4 3 1 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 KFO99472.1 - 0.014 15.1 10.0 0.014 15.1 7.0 3.9 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 KFO99472.1 - 0.015 15.2 3.6 0.015 15.2 2.5 5.8 2 1 4 6 6 5 0 bZIP transcription factor Laminin_II PF06009.7 KFO99472.1 - 0.023 14.4 23.9 0.12 12.1 5.1 3.0 2 1 1 3 3 3 0 Laminin Domain II ADIP PF11559.3 KFO99472.1 - 0.035 14.0 44.8 0.15 11.9 2.9 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 KFO99472.1 - 0.087 11.2 3.9 0.14 10.5 2.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.6 KFO99472.1 - 0.11 12.3 11.6 0.93 9.3 1.4 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.6 KFO99472.1 - 0.12 10.8 37.9 0.35 9.3 26.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Myosin_tail_1 PF01576.14 KFO99472.1 - 0.13 10.0 42.7 0.0085 13.8 25.5 1.4 1 1 0 1 1 1 0 Myosin tail Mod_r PF07200.8 KFO99472.1 - 0.14 12.0 36.0 0.73 9.7 5.4 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein WEMBL PF05701.6 KFO99472.1 - 0.17 10.2 39.7 0.38 9.1 24.9 2.6 2 1 0 2 2 2 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 KFO99472.1 - 0.18 9.1 37.6 0.34 8.1 26.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 KFO99472.1 - 0.29 10.5 36.4 0.23 10.8 14.3 2.8 1 1 1 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.4 KFO99472.1 - 0.37 10.9 25.9 0.056 13.5 1.3 3.6 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 KFO99472.1 - 0.38 8.8 33.2 0.039 12.1 18.9 2.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Lipoprotein_7 PF01540.11 KFO99472.1 - 0.39 9.7 21.5 2.5 7.1 7.2 2.5 1 1 1 2 2 2 0 Adhesin lipoprotein Hemerythrin PF01814.18 KFO99472.1 - 0.47 10.6 8.1 0.42 10.7 3.5 2.4 2 1 1 3 3 2 0 Hemerythrin HHE cation binding domain NPV_P10 PF05531.7 KFO99472.1 - 0.56 10.5 11.9 12 6.2 0.3 3.8 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 KFO99472.1 - 0.57 10.1 47.8 0.21 11.5 13.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Prominin PF05478.6 KFO99472.1 - 0.64 7.4 17.4 0.11 10.0 9.6 1.5 2 0 0 2 2 2 0 Prominin COG2 PF06148.6 KFO99472.1 - 0.72 9.7 18.6 2.7 7.8 3.5 3.7 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Cluap1 PF10234.4 KFO99472.1 - 0.86 8.7 32.4 2 7.5 10.4 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF972 PF06156.8 KFO99472.1 - 0.89 9.9 36.1 0.62 10.4 7.3 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KFO99472.1 - 1 7.7 33.9 7.1 4.9 23.9 1.9 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 KFO99472.1 - 1.1 9.1 49.7 1.2 8.9 2.7 3.9 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 KFO99472.1 - 1.2 8.6 38.9 2.4 7.6 8.5 3.8 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF869 PF05911.6 KFO99472.1 - 1.4 7.0 40.0 9.2 4.3 28.0 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Seryl_tRNA_N PF02403.17 KFO99472.1 - 1.4 8.9 37.2 0.63 10.0 9.7 3.9 2 1 3 5 5 4 0 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.1 KFO99472.1 - 2 8.6 31.8 0.1 12.8 8.6 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4600) ING PF12998.2 KFO99472.1 - 2.4 8.4 26.7 0.48 10.7 4.2 3.3 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Dor1 PF04124.7 KFO99472.1 - 2.5 6.4 24.8 0.16 10.4 12.9 1.9 2 1 1 3 3 2 0 Dor1-like family FlaC_arch PF05377.6 KFO99472.1 - 2.8 7.9 23.3 4.5 7.2 0.6 4.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) TMEM192 PF14802.1 KFO99472.1 - 2.9 6.6 5.9 2.3 7.0 1.8 2.4 1 1 1 2 2 2 0 TMEM192 family TPR_MLP1_2 PF07926.7 KFO99472.1 - 3.2 7.5 48.6 0.21 11.3 4.0 4.1 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DASH_Dad2 PF08654.5 KFO99472.1 - 3.6 7.6 18.9 0.71 9.9 3.3 3.8 2 1 2 4 4 3 0 DASH complex subunit Dad2 TMF_TATA_bd PF12325.3 KFO99472.1 - 3.7 7.2 40.6 0.52 10.0 7.1 3.6 2 1 2 4 4 3 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 KFO99472.1 - 4.3 7.1 46.3 5.6 6.7 5.1 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) COG6 PF06419.6 KFO99472.1 - 4.3 5.3 26.0 0.018 13.2 3.1 2.6 2 1 1 3 3 2 0 Conserved oligomeric complex COG6 DUF3450 PF11932.3 KFO99472.1 - 4.5 6.4 27.3 25 4.0 8.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF3461 PF11944.3 KFO99472.1 - 4.9 7.0 17.4 0.33 10.8 4.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) MerR-DNA-bind PF09278.6 KFO99472.1 - 5.1 7.5 18.0 0.69 10.3 0.8 4.5 1 1 3 4 4 3 0 MerR, DNA binding Lebercilin PF15619.1 KFO99472.1 - 5.3 6.4 42.9 0.34 10.2 11.3 3.4 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Leu_zip PF15294.1 KFO99472.1 - 6.8 5.7 41.9 7.6 5.5 23.9 2.4 1 1 1 2 2 2 0 Leucine zipper Fez1 PF06818.10 KFO99472.1 - 7.5 6.5 35.7 3.7 7.5 18.4 2.2 1 1 1 2 2 2 0 Fez1 Tnp_P_element PF12017.3 KFO99472.1 - 8.3 5.5 16.4 1.7 7.8 3.2 2.7 1 1 2 3 3 3 0 Transposase protein MAD PF05557.8 KFO99472.1 - 10 4.1 42.7 30 2.5 29.6 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein WH2 PF02205.15 KFO99473.1 - 2.8e-05 23.5 0.3 0.00027 20.4 0.1 2.3 2 0 0 2 2 2 1 WH2 motif Robl_LC7 PF03259.12 KFO99473.1 - 0.0093 15.5 0.0 0.028 13.9 0.0 1.8 1 0 0 1 1 1 1 Roadblock/LC7 domain PSI_PsaF PF02507.10 KFO99473.1 - 4.1 6.9 6.8 0.33 10.4 0.1 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III fn3 PF00041.16 KFO99474.1 - 2.8e-16 59.3 0.1 6.1e-10 39.1 0.0 2.9 3 0 0 3 3 3 2 Fibronectin type III domain SPRY PF00622.23 KFO99474.1 - 1.3e-14 54.3 0.0 3.4e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 SPRY domain Interfer-bind PF09294.5 KFO99474.1 - 4.5e-05 23.4 0.2 0.069 13.1 0.0 2.6 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III PRY PF13765.1 KFO99474.1 - 0.0039 16.6 0.1 0.069 12.6 0.0 2.5 2 0 0 2 2 2 1 SPRY-associated domain Tissue_fac PF01108.12 KFO99474.1 - 0.053 13.2 2.9 7 6.4 0.3 3.0 4 0 0 4 4 4 0 Tissue factor PDEase_I PF00233.14 KFO99475.1 - 4.6e-64 216.4 0.7 8.7e-64 215.5 0.5 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.19 KFO99475.1 - 6e-15 55.2 0.0 1.2e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KFO99475.1 - 1.1e-13 51.4 0.0 3.6e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KFO99475.1 - 2.8e-12 46.4 0.0 8.2e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KFO99475.1 - 1.4e-05 25.0 0.0 4.5e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 KFO99475.1 - 0.00023 20.8 0.0 0.00078 19.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 KFO99475.1 - 0.00087 19.3 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold CBS PF00571.23 KFO99475.1 - 0.13 12.0 0.0 0.46 10.3 0.0 1.9 1 0 0 1 1 1 0 CBS domain Amidinotransf PF02274.12 KFO99476.1 - 2.4e-14 53.0 0.0 1.1e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Amidinotransferase DNA_primase_S PF01896.14 KFO99476.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit AMP-binding PF00501.23 KFO99477.1 - 1.1e-47 162.4 0.0 1.4e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFO99477.1 - 8.7e-06 26.6 0.0 1.8e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.14 KFO99478.1 - 7.7e-164 544.5 0.0 9.5e-164 544.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFO99478.1 - 9.1e-05 21.7 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFO99478.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Ank_2 PF12796.2 KFO99479.1 - 1.2e-53 179.3 12.6 2.1e-22 79.2 0.4 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFO99479.1 - 3.3e-37 124.4 0.8 1.2e-11 43.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFO99479.1 - 1.3e-27 95.2 0.4 4.4e-09 36.3 0.0 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO99479.1 - 1.3e-27 93.0 0.5 4.1e-08 32.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFO99479.1 - 3.7e-24 84.6 0.3 2.3e-10 40.7 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) GrpE PF01025.14 KFO99479.1 - 1.6 8.2 9.9 4.4 6.8 6.9 1.7 1 0 0 1 1 1 0 GrpE MRP-S26 PF14943.1 KFO99479.1 - 2.7 7.4 15.4 0.76 9.3 8.2 1.9 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S26 UCH PF00443.24 KFO99480.1 - 4.8e-87 291.4 6.4 4.8e-87 291.4 4.4 3.1 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 KFO99480.1 - 2e-30 105.1 5.4 2e-30 105.1 3.7 2.9 2 1 0 2 2 2 1 USP8 dimerisation domain UCH_1 PF13423.1 KFO99480.1 - 7.5e-28 97.8 3.5 7.5e-28 97.8 2.4 2.5 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KFO99480.1 - 7.2e-09 35.9 0.0 7.8e-08 32.6 0.0 2.9 2 0 0 2 2 2 1 Rhodanese-like domain SAPS PF04499.10 KFO99480.1 - 0.00042 19.0 5.2 0.00042 19.0 3.6 2.3 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein Metallothio_Pro PF02069.11 KFO99480.1 - 0.1 12.4 0.6 0.41 10.5 0.4 2.0 2 0 0 2 2 2 0 Prokaryotic metallothionein UCH PF00443.24 KFO99481.1 - 8.1e-47 159.5 0.1 9.4e-47 159.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFO99481.1 - 4.7e-21 75.5 0.2 5.9e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ion_trans PF00520.26 KFO99482.1 - 7.5e-09 35.1 14.6 1.3e-08 34.3 9.9 1.6 1 1 0 1 1 1 1 Ion transport protein Peptidase_A22B PF04258.8 KFO99483.1 - 6.1e-86 288.5 19.1 1.1e-85 287.7 13.2 1.4 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.17 KFO99483.1 - 9.1e-13 47.7 0.0 1.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 PA domain Presenilin PF01080.12 KFO99483.1 - 0.00062 18.6 2.3 0.00062 18.6 1.6 2.2 2 0 0 2 2 2 2 Presenilin Tic20 PF09685.5 KFO99483.1 - 0.17 11.9 0.1 0.17 11.9 0.1 4.1 4 1 0 4 4 4 0 Tic20-like protein PKD_channel PF08016.7 KFO99483.1 - 0.19 10.0 11.8 0.36 9.2 8.2 1.4 1 0 0 1 1 1 0 Polycystin cation channel MMPL PF03176.10 KFO99483.1 - 1.7 7.3 4.2 3.3 6.3 0.1 2.3 2 0 0 2 2 2 0 MMPL family PBD PF00786.23 KFO99484.1 - 1.4e-05 25.4 0.2 1.8e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain AAA_18 PF13238.1 KFO99485.1 - 2.8e-09 37.3 0.2 7.6e-09 35.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain Pyr_redox_2 PF07992.9 KFO99486.1 - 3.7e-09 36.7 0.0 1.8e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Snapin_Pallidin PF14712.1 KFO99487.1 - 1.4e-21 76.5 2.9 1.7e-21 76.2 2.0 1.0 1 0 0 1 1 1 1 Snapin/Pallidin DUF2353 PF09789.4 KFO99487.1 - 0.0011 18.2 1.5 0.0016 17.7 0.3 1.6 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) ALS2CR8 PF15299.1 KFO99487.1 - 0.058 12.9 0.2 0.068 12.7 0.1 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 PIN_4 PF13638.1 KFO99487.1 - 0.067 13.3 0.2 0.078 13.0 0.2 1.1 1 0 0 1 1 1 0 PIN domain Tup_N PF08581.5 KFO99487.1 - 0.95 9.7 4.3 3.3 7.9 0.2 2.1 1 1 1 2 2 2 0 Tup N-terminal Cation_efflux PF01545.16 KFO99488.1 - 2.8e-67 226.8 13.0 3.2e-67 226.6 9.0 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1282 PF06930.7 KFO99488.1 - 0.28 10.8 10.2 1.9 8.1 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) DUF3112 PF11309.3 KFO99488.1 - 1.2 8.9 6.6 3.8 7.2 4.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Polysacc_synt_C PF14667.1 KFO99488.1 - 1.4 8.6 12.2 0.19 11.5 4.9 2.2 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain B12D PF06522.6 KFO99489.1 - 2.4e-19 68.8 0.0 2.5e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DTW PF03942.10 KFO99490.1 - 2.4e-52 177.1 0.0 3.3e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 DTW domain FGF PF00167.13 KFO99491.1 - 2.2e-45 153.3 2.0 3.1e-45 152.8 1.4 1.1 1 0 0 1 1 1 1 Fibroblast growth factor GalKase_gal_bdg PF10509.4 KFO99492.1 - 7.1e-24 82.8 0.0 1.6e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KFO99492.1 - 3.2e-14 52.7 0.4 8.9e-14 51.3 0.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFO99492.1 - 4.8e-13 49.1 0.0 2.3e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Fer2_BFD PF04324.10 KFO99492.1 - 0.06 13.4 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain PCI PF01399.22 KFO99493.1 - 9e-26 90.2 1.7 9e-26 90.2 1.2 2.6 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 KFO99493.1 - 1.6e-22 79.8 0.1 3.9e-22 78.5 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 KFO99493.1 - 0.02 14.6 1.1 53 3.9 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFO99493.1 - 0.073 13.0 1.4 20 5.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFO99493.1 - 0.12 12.0 1.9 13 5.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PID PF00640.18 KFO99494.1 - 1.4e-44 151.4 0.1 2.5e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 KFO99494.1 - 3.2e-16 58.8 0.0 1e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 SH2 domain EGF_CA PF07645.10 KFO99495.1 - 0 1068.6 718.6 1.5e-11 44.0 4.7 48.6 48 1 1 49 49 49 44 Calcium-binding EGF domain cEGF PF12662.2 KFO99495.1 - 1.7e-198 641.3 425.4 2.9e-09 36.3 0.6 50.0 50 0 0 50 50 50 44 Complement Clr-like EGF-like EGF PF00008.22 KFO99495.1 - 2.4e-133 433.2 656.6 1.1e-05 25.2 3.9 50.1 50 0 0 50 50 50 45 EGF-like domain TB PF00683.12 KFO99495.1 - 7.8e-122 396.6 137.0 6.2e-15 54.4 3.4 11.8 10 0 0 10 10 10 9 TB domain FXa_inhibition PF14670.1 KFO99495.1 - 1.4e-113 370.7 734.0 3.7e-10 39.7 6.3 49.9 45 4 6 51 51 51 44 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFO99495.1 - 1.8e-61 203.7 615.5 1.4e-10 40.8 7.9 49.3 49 1 1 50 50 50 40 EGF domain Plasmod_Pvs28 PF06247.6 KFO99495.1 - 0.0017 17.9 25.5 0.0017 17.9 17.6 24.9 8 6 16 26 26 26 12 Plasmodium ookinete surface protein Pvs28 dUTPase PF00692.14 KFO99496.1 - 2.9e-24 84.9 0.0 3.1e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 dUTPase AA_permease PF00324.16 KFO99497.1 - 6.9e-149 496.2 38.6 8.3e-149 495.9 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.5 KFO99497.1 - 1.6e-24 85.0 0.1 4.4e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 Amino acid permease N-terminal AA_permease_2 PF13520.1 KFO99497.1 - 9.4e-22 77.1 43.2 1.4e-21 76.5 30.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1682 PF07946.9 KFO99497.1 - 0.011 14.5 0.3 0.022 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Cortexin PF11057.3 KFO99498.1 - 5.1e-34 115.7 0.0 5.5e-34 115.6 0.0 1.0 1 0 0 1 1 1 1 Cortexin of kidney RRM_1 PF00076.17 KFO99499.1 - 5.9e-57 189.2 1.0 1.9e-19 69.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFO99499.1 - 1.4e-36 124.2 0.5 6.2e-12 45.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFO99499.1 - 6.3e-22 77.1 0.6 1.7e-06 27.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFO99499.1 - 7.3e-08 32.2 0.7 0.002 17.9 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 KFO99499.1 - 4.6e-07 29.4 0.0 0.0048 16.6 0.0 2.8 2 1 0 2 2 2 2 Limkain b1 DUF3932 PF13068.1 KFO99499.1 - 0.019 15.0 0.0 2.6 8.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Na_Ca_ex PF01699.19 KFO99500.1 - 2e-48 163.5 31.1 7.2e-25 87.2 8.3 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Sema PF01403.14 KFO99501.1 - 1.9e-121 405.6 0.1 3.3e-121 404.8 0.1 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFO99501.1 - 4.5e-08 33.1 2.3 1.1e-07 31.8 1.6 1.6 1 0 0 1 1 1 1 Plexin repeat Rav1p_C PF12234.3 KFO99502.1 - 8.2e-74 248.9 0.0 2.9e-71 240.4 0.0 3.1 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KFO99502.1 - 4.8e-25 86.4 26.7 4.5e-05 23.1 0.0 12.4 13 1 0 13 13 13 8 WD domain, G-beta repeat OLF PF02191.11 KFO99503.1 - 4.5e-64 216.1 0.5 5.3e-64 215.8 0.4 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Collagen PF01391.13 KFO99503.1 - 1.1e-16 60.0 64.8 5.8e-10 38.5 19.2 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) p450 PF00067.17 KFO99504.1 - 2.1e-105 352.9 0.2 2.5e-105 352.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2149 PF09919.4 KFO99504.1 - 0.25 11.4 2.3 0.76 9.8 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) DUF758 PF05527.6 KFO99505.1 - 1.2e-97 324.8 6.4 1.4e-97 324.7 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Seadorna_VP6 PF07407.6 KFO99505.1 - 0.017 13.9 0.7 0.017 13.9 0.5 1.5 1 1 1 2 2 2 0 Seadornavirus VP6 protein DUF2408 PF10303.4 KFO99505.1 - 0.031 14.3 2.0 0.077 13.1 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) PFO_beta_C PF12367.3 KFO99505.1 - 0.064 13.1 0.2 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Rsd_AlgQ PF04353.8 KFO99505.1 - 0.089 12.5 4.1 0.59 9.8 2.5 2.1 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DALR_1 PF05746.10 KFO99505.1 - 0.13 12.2 2.4 0.18 11.7 1.1 1.6 1 1 0 1 1 1 0 DALR anticodon binding domain SGIII PF15467.1 KFO99506.1 - 1.7e-224 745.9 33.0 2e-224 745.7 22.9 1.0 1 0 0 1 1 1 1 Secretogranin-3 DUF2680 PF10925.3 KFO99506.1 - 1.8e-07 30.9 4.8 0.24 11.2 0.1 4.6 3 1 0 3 3 3 3 Protein of unknown function (DUF2680) Phage_XkdX PF09693.5 KFO99506.1 - 0.08 12.4 0.1 27 4.3 0.0 3.5 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) DUF1227 PF06777.6 KFO99506.1 - 0.17 11.6 4.7 1.7 8.3 0.1 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1227) Plasmid_stabil PF05016.9 KFO99506.1 - 0.17 12.3 3.2 0.66 10.3 0.3 3.1 2 2 1 3 3 3 0 Plasmid stabilisation system protein DUF2201_N PF13203.1 KFO99506.1 - 0.59 9.2 7.9 0.13 11.4 1.7 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Hormone_2 PF00123.15 KFO99507.1 - 0.81 9.5 0.1 0.81 9.5 0.1 2.4 3 0 0 3 3 3 0 Peptide hormone Tropomodulin PF03250.9 KFO99508.1 - 2.3e-66 221.8 4.6 5.1e-66 220.7 3.2 1.6 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.1 KFO99508.1 - 0.028 14.4 1.1 0.29 11.3 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat PARP_reg PF02877.9 KFO99508.1 - 0.031 13.9 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain HTH_6 PF01418.12 KFO99508.1 - 0.18 11.5 0.6 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family LRR_4 PF12799.2 KFO99508.1 - 0.54 9.9 5.3 1.5 8.5 1.5 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Leo1 PF04004.8 KFO99509.1 - 6.2e-56 188.7 0.0 6.2e-56 188.7 0.0 3.5 2 1 0 2 2 2 1 Leo1-like protein Pkinase PF00069.20 KFO99510.1 - 1.7e-65 220.7 0.0 2.6e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99510.1 - 4.8e-26 91.3 0.0 1e-25 90.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFO99510.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family HPIP PF15226.1 KFO99510.1 - 0.0094 15.9 0.1 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 HCF-1 beta-propeller-interacting protein family Kinase-like PF14531.1 KFO99510.1 - 0.053 12.4 0.0 0.25 10.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like DIL PF01843.14 KFO99512.1 - 6.1e-35 119.2 1.8 6.1e-35 119.2 1.3 2.9 3 0 0 3 3 3 1 DIL domain IQ PF00612.22 KFO99512.1 - 0.00056 19.3 2.6 0.00056 19.3 1.8 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_13 PF13166.1 KFO99512.1 - 4.9 5.4 77.9 0.52 8.6 25.8 3.3 2 1 0 3 3 3 0 AAA domain Myosin_head PF00063.16 KFO99513.1 - 4.9e-253 841.2 13.3 5.7e-253 841.0 9.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFO99513.1 - 1.3e-17 61.6 26.6 8.2e-06 25.0 0.8 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KFO99513.1 - 0.0015 18.6 0.0 0.0057 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 KFO99513.1 - 0.021 14.3 0.5 0.086 12.3 0.3 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KFO99513.1 - 0.036 14.0 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Myosin_N PF02736.14 KFO99513.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain T2SE PF00437.15 KFO99513.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Myosin_head PF00063.16 KFO99514.1 - 3.4e-266 884.7 1.8 4e-266 884.4 1.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFO99514.1 - 4.1e-17 60.1 33.6 4.4e-05 22.7 2.5 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KFO99514.1 - 0.0016 18.5 0.1 0.0085 16.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFO99514.1 - 0.035 14.0 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KFO99514.1 - 0.085 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KFO99514.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Endosulfine PF04667.12 KFO99515.1 - 5e-15 55.2 0.9 5.8e-15 55.0 0.6 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4210 PF13915.1 KFO99516.1 - 3.9e-20 71.8 0.1 1.1e-19 70.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KFO99516.1 - 1.1e-19 70.0 0.4 2.9e-19 68.6 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis CUT PF02376.10 KFO99517.1 - 8.4e-32 108.8 0.4 1.5e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 CUT domain Homeobox PF00046.24 KFO99517.1 - 2.3e-10 39.9 0.6 4.4e-10 39.0 0.4 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFO99517.1 - 0.0011 18.6 0.0 0.0032 17.1 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain C2 PF00168.25 KFO99519.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 KFO99520.1 - 1.8e-54 183.2 1.5 8.5e-54 181.0 1.1 2.4 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.12 KFO99520.1 - 5.7e-41 138.9 0.2 5.7e-41 138.9 0.2 3.7 4 0 0 4 4 4 1 Domain of Unknown Function (DUF1041) C2 PF00168.25 KFO99520.1 - 5.9e-39 131.8 6.7 2.5e-25 88.1 0.3 3.2 3 0 0 3 3 3 2 C2 domain C1_1 PF00130.17 KFO99520.1 - 1.7e-10 40.4 6.4 3.7e-10 39.3 4.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.16 KFO99521.1 - 8.8e-21 73.5 37.9 1.3e-14 53.8 6.9 2.9 3 0 0 3 3 3 2 IBR domain DUF3287 PF11690.3 KFO99521.1 - 0.046 13.8 4.6 0.34 11.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) CwfJ_C_2 PF04676.9 KFO99521.1 - 0.072 13.5 0.8 21 5.6 0.0 2.4 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 2 POTRA_2 PF08479.6 KFO99521.1 - 0.09 12.4 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 POTRA domain, ShlB-type Guanylate_kin PF00625.16 KFO99522.1 - 3.2e-40 137.5 0.0 3.6e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase DUF258 PF03193.11 KFO99522.1 - 0.012 14.8 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PAP2 PF01569.16 KFO99524.1 - 6e-24 84.1 1.3 1e-23 83.4 0.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily zf-H2C2_2 PF13465.1 KFO99525.1 - 1.7e-13 50.1 16.7 1.5e-05 25.0 2.6 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO99525.1 - 1.8e-10 40.3 14.5 0.00024 21.2 1.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFO99525.1 - 2.6e-10 39.9 18.6 0.00024 21.2 1.7 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 KFO99525.1 - 7.2e-06 26.0 11.8 0.025 14.7 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFO99525.1 - 7.5e-05 22.7 10.9 0.3 11.2 1.5 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFO99525.1 - 0.0012 18.9 1.7 0.0012 18.9 1.2 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.1 KFO99525.1 - 0.0012 18.5 3.1 2.1 8.1 0.0 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-C2H2_6 PF13912.1 KFO99525.1 - 0.0016 18.2 12.5 0.086 12.7 0.2 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger XPA_N PF01286.13 KFO99525.1 - 0.0017 18.0 5.0 0.057 13.0 0.1 3.1 3 0 0 3 3 3 1 XPA protein N-terminal DZR PF12773.2 KFO99525.1 - 0.0085 15.8 3.8 0.018 14.8 0.6 2.1 2 0 0 2 2 2 1 Double zinc ribbon zf-C3HC4_3 PF13920.1 KFO99525.1 - 0.025 14.2 5.1 0.34 10.6 1.9 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_4 PF07975.7 KFO99525.1 - 0.025 14.5 5.7 0.89 9.6 1.9 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2H2_2 PF12756.2 KFO99525.1 - 0.026 14.6 10.0 0.53 10.4 0.4 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-RING_5 PF14634.1 KFO99525.1 - 0.034 13.8 5.9 1.2 8.9 2.3 2.8 2 1 1 3 3 3 0 zinc-RING finger domain zf-CHY PF05495.7 KFO99525.1 - 0.037 14.1 5.6 0.074 13.2 3.9 1.6 1 1 0 1 1 1 0 CHY zinc finger zinc-ribbons_6 PF07191.7 KFO99525.1 - 0.037 13.8 2.8 0.4 10.5 0.1 2.2 1 1 0 2 2 2 0 zinc-ribbons zf-HIT PF04438.11 KFO99525.1 - 0.044 13.4 5.9 5.7 6.6 0.2 3.1 3 0 0 3 3 3 0 HIT zinc finger Elf1 PF05129.8 KFO99525.1 - 0.047 13.3 8.0 0.34 10.6 1.4 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like FYVE PF01363.16 KFO99525.1 - 0.053 13.4 8.2 1.5 8.7 0.3 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-AN1 PF01428.11 KFO99525.1 - 0.056 13.3 5.4 1.7 8.5 0.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C2HC_2 PF13913.1 KFO99525.1 - 0.071 12.7 0.5 0.071 12.7 0.3 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type LIM PF00412.17 KFO99525.1 - 0.099 12.7 4.4 0.098 12.7 1.1 2.1 2 1 0 2 2 2 0 LIM domain Zn-ribbon_8 PF09723.5 KFO99525.1 - 0.15 12.0 9.2 2.5 8.1 2.6 3.1 2 1 0 2 2 2 0 Zinc ribbon domain Rtf2 PF04641.7 KFO99525.1 - 0.18 10.9 3.8 0.55 9.3 0.2 2.3 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_2 PF13639.1 KFO99525.1 - 0.2 11.5 4.1 22 4.9 3.8 2.9 1 1 1 2 2 2 0 Ring finger domain C1_2 PF03107.11 KFO99525.1 - 0.23 11.6 5.5 25 5.1 0.1 3.1 3 0 0 3 3 3 0 C1 domain Rad50_zn_hook PF04423.9 KFO99525.1 - 0.3 10.5 4.9 1.1 8.7 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif TFIIS_C PF01096.13 KFO99525.1 - 0.3 10.7 5.7 3.3 7.4 1.0 3.0 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-FCS PF06467.9 KFO99525.1 - 0.31 10.7 6.6 2.1 8.0 0.1 3.0 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Endonuclease_7 PF02945.10 KFO99525.1 - 0.32 10.7 6.9 0.11 12.1 1.2 1.9 1 1 1 2 2 2 0 Recombination endonuclease VII zf-RING_3 PF14369.1 KFO99525.1 - 0.33 10.9 4.4 5 7.2 0.3 2.9 3 0 0 3 3 3 0 zinc-finger YyzF PF14116.1 KFO99525.1 - 0.38 10.7 4.1 24 5.0 0.1 3.0 3 0 0 3 3 3 0 YyzF-like protein DUF2256 PF10013.4 KFO99525.1 - 0.39 10.5 7.1 26 4.6 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.17 KFO99525.1 - 0.4 10.4 6.2 2.9 7.6 1.0 2.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH PF01844.18 KFO99525.1 - 0.41 10.5 10.5 2.3 8.1 0.2 3.1 3 0 0 3 3 3 0 HNH endonuclease DUF2321 PF10083.4 KFO99525.1 - 0.44 10.0 6.1 0.35 10.3 1.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Cript PF10235.4 KFO99525.1 - 0.45 10.9 0.2 0.45 10.9 0.1 2.5 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT zf-CHCC PF10276.4 KFO99525.1 - 0.58 10.0 4.6 32 4.4 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-Sec23_Sec24 PF04810.10 KFO99525.1 - 0.58 9.7 2.9 2.1 7.9 0.0 2.7 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger GAGA PF09237.6 KFO99525.1 - 0.97 9.0 4.1 1.4 8.5 0.2 2.4 1 1 0 2 2 2 0 GAGA factor DUF2225 PF09986.4 KFO99525.1 - 1.2 8.5 5.3 0.4 10.1 0.2 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Rubredoxin PF00301.15 KFO99525.1 - 1.6 8.6 6.5 27 4.7 0.3 3.0 2 1 1 3 3 3 0 Rubredoxin DUF3449 PF11931.3 KFO99525.1 - 1.7 8.0 9.9 4.2 6.8 0.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3449) Evr1_Alr PF04777.8 KFO99525.1 - 1.9 8.4 6.1 7.1 6.6 0.1 2.7 1 1 2 3 3 3 0 Erv1 / Alr family zf-ISL3 PF14690.1 KFO99525.1 - 2.6 8.1 10.1 7.1 6.7 0.3 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 CpXC PF14353.1 KFO99525.1 - 2.6 8.0 7.3 6.3 6.7 1.6 2.7 1 1 1 2 2 2 0 CpXC protein Baculo_ME53 PF06061.6 KFO99525.1 - 3 6.7 7.0 5 6.0 0.3 2.4 1 1 2 3 3 3 0 Baculoviridae ME53 C1_3 PF07649.7 KFO99525.1 - 3 7.9 6.1 50 4.0 0.1 3.2 3 0 0 3 3 3 0 C1-like domain zinc_ribbon_4 PF13717.1 KFO99525.1 - 3.6 7.3 5.7 25 4.6 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KFO99525.1 - 4 7.3 8.4 4.7 7.0 1.6 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain WD40 PF00400.27 KFO99527.1 - 5.8e-08 32.3 6.7 0.9 9.5 0.0 7.2 8 1 0 8 8 8 3 WD domain, G-beta repeat PQQ PF01011.16 KFO99527.1 - 0.019 14.4 0.2 6 6.5 0.0 3.8 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.1 KFO99527.1 - 0.05 13.0 0.9 3.7 6.9 0.0 3.4 4 1 0 4 4 4 0 PQQ-like domain Pkinase_Tyr PF07714.12 KFO99529.1 - 4.2e-104 347.2 0.0 5.6e-104 346.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFO99529.1 - 3e-48 164.2 0.0 4.4e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFO99529.1 - 3e-33 113.5 0.0 2.5e-11 43.2 0.0 3.7 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99529.1 - 8.2e-29 99.5 0.0 5.3e-10 39.2 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFO99529.1 - 7.9e-19 67.9 0.3 4.9e-05 23.7 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFO99529.1 - 7.9e-17 61.1 1.4 9.5e-05 22.4 0.1 5.1 6 1 0 6 6 6 3 Immunoglobulin domain V-set PF07686.12 KFO99529.1 - 5e-16 58.6 0.5 0.0017 18.2 0.0 5.3 3 2 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO99529.1 - 0.03 14.2 3.5 3.1 7.7 0.1 4.3 3 1 2 5 5 5 0 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.1 KFO99529.1 - 0.071 12.0 0.1 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF1083 PF06452.6 KFO99529.1 - 0.089 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1083) ATE_C PF04377.10 KFO99530.1 - 9.4e-45 151.7 1.1 3e-44 150.1 0.3 2.1 2 1 1 3 3 3 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KFO99530.1 - 2.4e-10 40.0 2.0 6.4e-10 38.6 1.4 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Podoplanin PF05808.6 KFO99530.1 - 0.058 12.9 1.4 0.089 12.3 0.9 1.2 1 0 0 1 1 1 0 Podoplanin Nse4_C PF08743.5 KFO99531.1 - 2e-25 88.6 0.0 4.5e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KFO99531.1 - 1.3e-16 60.2 1.1 3.1e-16 58.9 0.7 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Plant_tran PF04827.9 KFO99531.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein TACC PF05010.9 KFO99532.1 - 9.1e-82 273.8 33.0 9.1e-82 273.8 22.9 1.8 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) GSH-S_N PF02951.9 KFO99532.1 - 0.055 13.2 0.3 0.2 11.4 0.2 2.0 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain IncA PF04156.9 KFO99532.1 - 4.3 6.8 35.9 2.4 7.6 14.4 3.2 1 1 2 3 3 3 0 IncA protein DUF3584 PF12128.3 KFO99532.1 - 5.9 4.0 30.4 2.7 5.2 8.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Methyltrn_RNA_4 PF09936.4 KFO99532.1 - 6.2 6.2 8.4 7.6 5.9 1.8 2.3 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase PH PF00169.24 KFO99533.1 - 2.2e-31 108.1 0.1 1.1e-18 67.2 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFO99533.1 - 6.5e-13 48.9 1.2 5.4e-07 29.8 0.3 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFO99533.1 - 2.3e-12 46.8 0.1 1.6e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 KFO99533.1 - 1.1e-07 31.7 0.0 0.0089 15.9 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 KFO99533.1 - 1.9e-07 31.2 0.3 0.031 14.4 0.1 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 KFO99533.1 - 4e-05 23.4 1.0 0.0066 16.3 0.1 2.8 2 2 0 2 2 2 1 PH domain Trypsin_2 PF13365.1 KFO99534.1 - 1.4e-22 79.8 0.3 2.3e-22 79.2 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KFO99534.1 - 1.2e-16 60.9 0.0 1.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ PF00595.19 KFO99534.1 - 7.4e-10 38.8 0.2 2.2e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO99534.1 - 1.1e-09 38.0 0.9 1.1e-09 38.0 0.6 2.1 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.4 KFO99534.1 - 1e-06 27.5 0.8 0.015 13.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.8 KFO99534.1 - 1.4e-05 24.2 0.2 0.0086 15.0 0.1 2.1 1 1 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 LSM PF01423.17 KFO99534.1 - 0.0047 16.4 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 LSM domain GRASP55_65 PF04495.9 KFO99534.1 - 0.015 15.3 0.1 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Zona_pellucida PF00100.18 KFO99535.1 - 3.5e-09 36.5 0.0 3.7e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 KFO99536.1 - 1.1e-22 80.7 2.4 1.2e-22 80.6 1.6 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR PF00530.13 KFO99537.1 - 4.7e-37 126.3 5.0 5.2e-37 126.1 3.5 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFO99537.1 - 8.6e-05 22.7 2.7 0.00015 21.9 1.9 1.6 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain TIG PF01833.19 KFO99538.1 - 0.39 10.7 10.8 7 6.7 1.0 3.2 1 1 1 2 2 2 0 IPT/TIG domain Adeno_E1A PF02703.9 KFO99538.1 - 1.7 8.0 9.9 16 4.8 0.4 3.0 1 1 1 2 2 2 0 Early E1A protein DUF281 PF03436.8 KFO99538.1 - 3.1 7.9 12.8 9.4 6.3 1.8 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF281) Zona_pellucida PF00100.18 KFO99539.1 - 4.2e-09 36.2 0.0 4.4e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 KFO99540.1 - 7e-24 84.6 3.9 7.6e-24 84.5 2.7 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain SRCR PF00530.13 KFO99541.1 - 7.1e-34 116.1 4.3 7.9e-34 115.9 3.0 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFO99541.1 - 0.0044 17.2 0.2 0.008 16.3 0.1 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.13 KFO99542.1 - 4.2e-130 424.7 56.4 5e-34 116.5 6.5 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFO99542.1 - 9.5e-18 64.2 22.6 0.00025 21.2 0.6 4.9 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain Phage_30_3 PF08010.6 KFO99542.1 - 0.0024 17.3 0.2 27 4.2 0.0 3.7 4 0 0 4 4 4 0 Bacteriophage protein GP30.3 XylR_N PF06505.6 KFO99542.1 - 0.14 11.6 0.0 1.1e+02 2.2 0.0 3.5 3 0 0 3 3 3 0 Activator of aromatic catabolism DFP PF04127.10 KFO99542.1 - 0.26 10.9 0.0 1.2e+02 2.1 0.0 3.1 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein SapB_2 PF03489.12 KFO99542.1 - 7.4 6.7 13.3 1.6e+02 2.4 0.0 6.6 7 0 0 7 7 7 0 Saposin-like type B, region 2 Zona_pellucida PF00100.18 KFO99543.1 - 4.2e-11 42.7 0.2 4.4e-11 42.7 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 KFO99544.1 - 7.3e-24 84.6 4.0 7.9e-24 84.5 2.8 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain RVT_1 PF00078.22 KFO99545.1 - 0.045 13.0 0.0 0.083 12.2 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ELL PF10390.4 KFO99546.1 - 2.9e-84 282.6 1.4 2.9e-84 282.6 1.0 2.3 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.8 KFO99546.1 - 3.3e-32 111.2 6.2 3.3e-32 111.2 4.3 2.4 3 0 0 3 3 3 1 Occludin homology domain Imm3 PF14425.1 KFO99546.1 - 0.62 10.0 4.3 0.54 10.2 0.2 2.5 3 0 0 3 3 3 0 Immunity protein Imm3 BTB PF00651.26 KFO99547.1 - 1e-25 89.8 1.5 1.2e-18 67.0 0.2 3.4 3 1 0 3 3 3 2 BTB/POZ domain Ras PF00071.17 KFO99547.1 - 4.5e-05 22.9 0.0 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Ras family CH PF00307.26 KFO99547.1 - 0.084 12.9 0.1 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain Rieske_2 PF13806.1 KFO99548.1 - 2.5e-08 33.5 0.0 1.6e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 KFO99548.1 - 0.0018 17.7 0.1 0.0073 15.8 0.0 1.9 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain DUF1347 PF07079.6 KFO99548.1 - 0.045 11.9 0.0 0.055 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) Sulfatase PF00884.18 KFO99549.1 - 1.2e-42 146.2 0.3 2e-42 145.4 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KFO99549.1 - 2.4e-06 27.1 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.12 KFO99549.1 - 4.6e-06 25.3 0.1 4.2e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 KFO99549.1 - 6.8e-05 22.3 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 KFO99549.1 - 0.0074 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF4572 PF15139.1 KFO99549.1 - 0.11 12.2 1.0 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4572) RVT_1 PF00078.22 KFO99550.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) COG5 PF10392.4 KFO99551.1 - 0.00019 21.4 15.8 0.0011 18.8 0.2 3.3 1 1 2 3 3 3 2 Golgi transport complex subunit 5 Peptidase_C16 PF01831.12 KFO99551.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase C16 family Bacillus_HBL PF05791.6 KFO99551.1 - 0.11 11.8 18.6 0.9 8.8 0.7 3.6 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.7 KFO99551.1 - 0.44 10.3 8.2 13 5.5 0.3 3.4 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KFO99551.1 - 0.48 10.5 19.5 0.38 10.8 0.3 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ALMT PF11744.3 KFO99551.1 - 1.6 7.2 10.2 1.5 7.3 0.7 2.1 1 1 1 2 2 2 0 Aluminium activated malate transporter DUF1515 PF07439.6 KFO99551.1 - 2.4 8.0 5.9 0.37 10.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) FlaC_arch PF05377.6 KFO99551.1 - 4.4 7.2 9.3 4.5 7.2 0.0 4.1 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF4172 PF13776.1 KFO99551.1 - 5.3 7.1 11.3 11 6.2 0.6 4.2 3 2 1 5 5 5 0 Domain of unknown function (DUF4172) PspB PF06667.7 KFO99551.1 - 7.2 6.6 9.8 1 9.3 0.4 3.4 2 1 0 3 3 3 0 Phage shock protein B DivIC PF04977.10 KFO99551.1 - 9 5.8 17.8 0.69 9.4 0.2 4.2 4 0 0 4 4 4 0 Septum formation initiator C2 PF00168.25 KFO99553.1 - 9.5e-66 217.6 0.1 8.3e-23 80.0 0.0 3.4 3 0 0 3 3 3 3 C2 domain PRT_C PF08372.5 KFO99553.1 - 1.1e-07 31.4 8.5 3e-07 30.0 0.1 3.2 2 1 1 3 3 3 1 Plant phosphoribosyltransferase C-terminal CEP76-C2 PF15627.1 KFO99553.1 - 0.001 18.6 0.0 0.52 9.8 0.0 3.1 3 0 0 3 3 3 2 CEP76 C2 domain DUF639 PF04842.7 KFO99553.1 - 0.0016 16.7 0.1 0.0023 16.1 0.1 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) Pex24p PF06398.6 KFO99553.1 - 0.0019 17.0 0.7 0.0036 16.1 0.5 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Dsh_C PF12316.3 KFO99555.1 - 9.7 6.2 12.3 9.4 6.2 8.6 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Ank PF00023.25 KFO99556.1 - 1.5e-21 75.0 1.0 6.4e-06 25.7 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFO99556.1 - 1.9e-20 72.9 0.2 2.7e-13 50.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFO99556.1 - 2e-17 61.5 0.1 7e-05 22.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KFO99556.1 - 4.5e-17 61.6 0.4 4.9e-08 32.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO99556.1 - 8.1e-16 58.0 0.2 1.9e-09 37.7 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF4110 PF13422.1 KFO99556.1 - 0.041 13.7 0.6 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Dpy-30 PF05186.8 KFO99557.1 - 0.092 12.2 0.2 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 Dpy-30 motif Arb2 PF09757.4 KFO99558.1 - 8.8e-35 119.7 0.3 1e-33 116.2 0.0 2.3 2 0 0 2 2 2 1 Arb2 domain Abhydrolase_6 PF12697.2 KFO99558.1 - 0.00025 21.0 0.0 0.00093 19.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFO99558.1 - 0.0044 16.7 0.0 0.0086 15.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO99558.1 - 0.062 12.8 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2674 PF10879.3 KFO99558.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) Synaphin PF05835.7 KFO99558.1 - 0.36 10.9 7.9 0.75 9.9 5.5 1.5 1 0 0 1 1 1 0 Synaphin protein Arrestin_N PF00339.24 KFO99560.1 - 1.3e-35 122.4 0.1 8.7e-35 119.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFO99560.1 - 6.4e-24 84.6 0.0 1.1e-19 70.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 KFO99560.1 - 0.0013 17.5 0.1 0.011 14.5 0.1 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Calx-beta PF03160.9 KFO99561.1 - 8.2e-246 795.8 100.7 8.2e-15 54.5 0.2 38.7 40 1 0 40 40 40 33 Calx-beta domain Laminin_G_3 PF13385.1 KFO99561.1 - 8.5e-16 58.5 0.3 4.1e-15 56.3 0.1 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily 7tm_2 PF00002.19 KFO99561.1 - 2.8e-15 56.0 25.2 4.6e-15 55.3 17.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) EPTP PF03736.12 KFO99561.1 - 4.2e-08 32.7 9.2 0.001 18.7 0.5 5.9 5 0 0 5 5 5 3 EPTP domain GPS PF01825.16 KFO99561.1 - 6.9e-08 32.4 2.1 1.4e-07 31.4 1.4 1.6 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain PAN_4 PF14295.1 KFO99561.1 - 0.33 10.6 0.6 0.7 9.6 0.4 1.5 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.6 KFO99561.1 - 0.7 9.7 0.4 2.1 8.2 0.0 1.9 2 0 0 2 2 2 0 PAN-like domain LysM PF01476.15 KFO99562.1 - 3.4e-05 23.6 0.2 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 LysM domain YqhR PF11085.3 KFO99562.1 - 0.018 14.5 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR RNA_pol_3_Rpc31 PF11705.3 KFO99563.1 - 1.6e-30 106.7 22.2 1.9e-30 106.5 15.4 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 KFO99563.1 - 0.0021 16.6 25.2 0.0026 16.3 17.5 1.0 1 0 0 1 1 1 1 Daxx Family VID27 PF08553.5 KFO99563.1 - 1.9 6.5 17.8 2.5 6.2 12.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2413 PF10310.4 KFO99563.1 - 2.7 6.6 15.6 3.5 6.3 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) BTV_NS2 PF04514.7 KFO99563.1 - 3.2 6.5 18.3 4.1 6.1 12.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GET2 PF08690.5 KFO99563.1 - 4.5 6.4 6.1 5.7 6.1 4.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 EF-hand_1 PF00036.27 KFO99564.1 - 2.8e-22 76.2 14.2 2.4e-07 29.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFO99564.1 - 4.4e-20 71.5 10.7 8.3e-10 38.6 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFO99564.1 - 4.7e-19 66.5 11.7 2.2e-06 27.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KFO99564.1 - 3.6e-12 45.7 15.1 3.8e-07 29.6 0.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KFO99564.1 - 1.5e-11 43.0 15.5 7.8e-05 21.8 0.3 4.7 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFO99564.1 - 9.4e-06 25.4 0.2 0.081 12.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0231 PF06062.6 KFO99564.1 - 0.022 14.6 1.3 0.1 12.4 0.4 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) MgtE_N PF03448.12 KFO99564.1 - 0.037 14.3 4.3 0.054 13.8 1.0 2.5 1 1 1 2 2 2 0 MgtE intracellular N domain Cas_Csn2 PF09711.5 KFO99564.1 - 0.042 13.5 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) EF-hand_4 PF12763.2 KFO99564.1 - 0.055 13.2 3.8 0.058 13.1 0.2 2.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 KFO99564.1 - 0.11 12.0 0.1 0.87 9.1 0.0 2.3 1 1 2 3 3 3 0 Caleosin related protein SRF-TF PF00319.13 KFO99565.1 - 7.1e-19 66.7 0.3 1.2e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.3 KFO99565.1 - 8.5e-14 50.8 0.0 2.5e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat Tmemb_161AB PF10268.4 KFO99566.1 - 6.9e-238 789.9 14.2 7.7e-238 789.8 9.8 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB RasGAP PF00616.14 KFO99567.1 - 1.2e-41 142.5 1.8 1.7e-41 142.0 0.6 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase SH2 PF00017.19 KFO99567.1 - 1.7e-23 82.1 0.1 3.3e-21 74.8 0.0 2.8 2 0 0 2 2 2 1 SH2 domain PH PF00169.24 KFO99567.1 - 1.9e-16 60.1 0.1 6.4e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 KFO99567.1 - 4.1e-10 38.8 0.0 8.7e-10 37.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain C2 PF00168.25 KFO99567.1 - 1.4e-08 34.4 0.1 3.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.1 KFO99567.1 - 1.1e-06 28.1 0.0 2.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 KFO99567.1 - 5.1e-05 23.4 0.4 0.00067 19.8 0.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain COX7C PF02935.11 KFO99568.1 - 4.1e-19 68.1 0.2 4.3e-19 68.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Yae1_N PF09811.4 KFO99569.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Lipase_GDSL_2 PF13472.1 KFO99570.1 - 1.7e-05 25.0 0.0 3.5e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family F5_F8_type_C PF00754.20 KFO99571.1 - 1.3e-63 212.5 6.3 8.1e-34 116.2 0.7 2.1 2 0 0 2 2 2 2 F5/8 type C domain EGF PF00008.22 KFO99571.1 - 5e-23 80.6 38.8 2e-08 34.0 5.3 3.6 3 0 0 3 3 3 3 EGF-like domain EGF_2 PF07974.8 KFO99571.1 - 6.1e-06 26.3 40.1 0.013 15.6 5.1 3.8 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.2 KFO99571.1 - 7.3e-05 22.5 20.6 0.02 14.9 1.1 4.0 3 0 0 3 3 3 3 Human growth factor-like EGF DUF1438 PF07270.6 KFO99571.1 - 0.088 12.6 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) cEGF PF12662.2 KFO99571.1 - 0.82 9.3 24.3 0.17 11.5 2.2 4.0 3 1 0 3 3 3 0 Complement Clr-like EGF-like Xlink PF00193.12 KFO99573.1 - 9.4e-63 208.3 0.3 1.1e-36 124.7 0.0 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 KFO99573.1 - 1.2e-12 47.7 0.0 2.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFO99573.1 - 4.1e-05 23.3 0.0 0.0001 22.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Foamy_BEL PF03274.9 KFO99573.1 - 0.0002 20.6 0.1 0.00033 19.9 0.1 1.3 1 0 0 1 1 1 1 Foamy virus BEL 1/2 protein Ig_2 PF13895.1 KFO99573.1 - 0.00074 19.5 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO99573.1 - 0.09 12.9 0.1 0.24 11.5 0.1 1.7 1 1 0 1 1 1 0 Immunoglobulin domain RVT_1 PF00078.22 KFO99574.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) XRCC4 PF06632.7 KFO99575.1 - 8e-106 353.7 7.5 8.8e-106 353.6 5.2 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 RHH_2 PF03693.9 KFO99575.1 - 0.0037 17.3 1.2 1.5 9.0 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0156) DUF927 PF06048.6 KFO99575.1 - 0.033 13.4 0.1 0.049 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) DUF2408 PF10303.4 KFO99575.1 - 0.22 11.6 3.9 0.13 12.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Prefoldin_2 PF01920.15 KFO99575.1 - 1.1 9.0 11.4 0.17 11.6 0.5 2.9 3 0 0 3 3 3 0 Prefoldin subunit DUF1242 PF06842.7 KFO99576.1 - 3.5e-16 58.4 1.9 4e-16 58.2 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) ATP-synt_8 PF00895.15 KFO99576.1 - 0.039 14.1 0.1 0.039 14.1 0.1 1.0 1 0 0 1 1 1 0 ATP synthase protein 8 LST1 PF05083.8 KFO99576.1 - 0.14 12.1 0.3 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 LST-1 protein ATP-synt_S1 PF05827.7 KFO99577.1 - 2.7e-09 36.7 0.2 3.7e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.12 KFO99577.1 - 9.7e-07 28.2 0.2 1.3e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Ribosom_S12_S23 PF00164.20 KFO99578.1 - 2.8e-42 142.9 1.1 3.5e-42 142.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Autophagy_act_C PF03987.10 KFO99579.1 - 9.8e-21 73.7 0.3 1.7e-20 72.9 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain SSDP PF04503.8 KFO99580.1 - 1.2e-113 379.6 57.6 5.6e-111 370.9 40.0 2.0 1 1 0 1 1 1 1 Single-stranded DNA binding protein, SSDP 4HBT PF03061.17 KFO99581.1 - 1.2e-19 70.1 0.8 7.5e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily PTSIIB_sorb PF03830.10 KFO99581.1 - 0.0088 15.9 1.4 7.3 6.4 0.0 3.1 3 0 0 3 3 3 2 PTS system sorbose subfamily IIB component Mer2 PF09074.5 KFO99581.1 - 0.053 13.4 0.2 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Mer2 START PF01852.14 KFO99582.1 - 2.7e-19 69.3 0.2 3.3e-19 69.0 0.2 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc2 PF10604.4 KFO99582.1 - 0.041 14.0 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport zf-CCHC PF00098.18 KFO99583.1 - 2.3e-16 58.8 25.0 2.9e-06 26.9 0.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 KFO99583.1 - 1.7e-05 24.3 23.5 0.032 13.9 0.4 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 KFO99583.1 - 0.00055 19.3 15.7 0.21 11.1 0.4 4.2 3 1 1 4 4 4 3 Zinc knuckle eIF3g PF12353.3 KFO99583.1 - 0.022 14.6 23.5 0.18 11.6 0.2 4.1 1 1 3 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G DUF4200 PF13863.1 KFO99583.1 - 0.022 14.6 11.9 0.022 14.6 8.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-CCHC_5 PF14787.1 KFO99583.1 - 0.032 13.6 0.2 0.032 13.6 0.1 2.7 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Inhibitor_I9 PF05922.11 KFO99583.1 - 0.11 13.0 0.1 0.18 12.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 Prim_Zn_Ribbon PF08273.7 KFO99583.1 - 4.7 7.3 12.1 3.9 7.6 0.1 3.7 4 0 0 4 4 4 0 Zinc-binding domain of primase-helicase DUF2058 PF09831.4 KFO99583.1 - 7.2 6.4 10.2 11 5.8 7.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) zf-CCHC_3 PF13917.1 KFO99583.1 - 8.3 6.2 14.3 9.9 5.9 0.5 4.1 2 1 2 4 4 4 0 Zinc knuckle ATP-gua_Ptrans PF00217.14 KFO99584.1 - 1.6e-102 342.0 0.0 1.9e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 KFO99584.1 - 2.5e-34 117.2 0.0 4e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain MutS_V PF00488.16 KFO99586.1 - 5.1e-87 291.1 0.0 9e-87 290.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFO99586.1 - 4.6e-39 134.3 0.6 8e-39 133.5 0.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KFO99586.1 - 1.5e-10 41.2 0.2 5.8e-10 39.3 0.0 2.2 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 KFO99586.1 - 1.8e-06 28.0 0.1 6.1e-06 26.3 0.1 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_22 PF13401.1 KFO99586.1 - 0.068 13.3 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain DHFR_1 PF00186.14 KFO99587.1 - 7.8e-28 97.0 0.0 8.6e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase DUF2181 PF10223.4 KFO99588.1 - 3.4e-85 285.3 0.2 3.8e-85 285.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) GAGA PF09237.6 KFO99588.1 - 0.18 11.4 0.3 0.36 10.4 0.2 1.4 1 0 0 1 1 1 0 GAGA factor DUF3480 PF11979.3 KFO99589.1 - 3.2e-93 312.1 0.0 3.6e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) DUF3480 PF11979.3 KFO99590.1 - 7.5e-27 93.8 0.2 1.7e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) FYVE PF01363.16 KFO99590.1 - 5e-20 71.1 15.0 1.5e-19 69.6 10.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger LPP20 PF02169.11 KFO99591.1 - 0.14 12.2 0.8 0.51 10.4 0.6 2.0 1 0 0 1 1 1 0 LPP20 lipoprotein EHN PF06441.7 KFO99591.1 - 2.9 7.8 9.2 0.053 13.4 0.6 2.4 3 0 0 3 3 3 0 Epoxide hydrolase N terminus AAA_18 PF13238.1 KFO99592.1 - 7.6e-26 90.9 0.2 1.5e-25 89.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFO99592.1 - 1.6e-13 51.5 0.1 3.8e-13 50.3 0.0 1.5 1 1 1 2 2 2 1 AAA domain SKI PF01202.17 KFO99592.1 - 2.4e-05 24.2 1.4 0.005 16.7 0.0 2.7 2 1 1 3 3 3 1 Shikimate kinase AAA_28 PF13521.1 KFO99592.1 - 4e-05 23.6 0.0 7.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFO99592.1 - 0.00013 22.1 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFO99592.1 - 0.001 18.9 0.1 0.0029 17.5 0.1 1.8 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFO99592.1 - 0.0015 18.6 0.0 0.0067 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 KFO99592.1 - 0.0081 16.0 0.4 0.035 13.9 0.1 1.9 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.5 KFO99592.1 - 0.023 13.8 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF258 PF03193.11 KFO99592.1 - 0.03 13.5 0.1 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KFO99592.1 - 0.034 13.7 0.2 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFO99592.1 - 0.043 13.5 0.0 0.093 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 KFO99592.1 - 0.049 13.5 0.1 0.16 11.9 0.1 2.0 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_14 PF13173.1 KFO99592.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFO99592.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 KFO99592.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.10 KFO99593.1 - 1.2e-171 571.9 0.1 1.5e-171 571.6 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KFO99593.1 - 2.6e-06 27.5 0.0 6.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFO99593.1 - 2.7e-06 26.6 0.0 4.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KFO99593.1 - 7.2e-06 26.2 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFO99593.1 - 7.8e-06 26.0 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFO99593.1 - 4.4e-05 23.1 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KFO99593.1 - 0.0005 20.3 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFO99593.1 - 0.00072 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 KFO99593.1 - 0.00086 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFO99593.1 - 0.0015 19.3 0.0 0.0039 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFO99593.1 - 0.0024 17.6 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFO99593.1 - 0.003 17.4 0.0 0.0078 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFO99593.1 - 0.005 17.0 0.0 0.021 15.0 0.0 2.2 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.7 KFO99593.1 - 0.074 12.7 0.2 0.48 10.0 0.1 2.4 2 1 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 KFO99593.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DMA PF03474.9 KFO99593.1 - 0.084 12.7 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 DMRTA motif AAA_11 PF13086.1 KFO99593.1 - 0.1 12.1 2.4 0.17 11.3 0.6 2.2 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KFO99593.1 - 0.11 12.0 0.1 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KFO99593.1 - 0.13 11.9 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 His_Phos_2 PF00328.17 KFO99594.1 - 1.7e-41 142.7 0.2 2e-41 142.4 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Kinesin PF00225.18 KFO99595.1 - 4e-94 315.0 0.1 4e-94 315.0 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain HECT PF00632.20 KFO99596.1 - 3.2e-47 161.2 0.1 3.4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SNARE PF05739.14 KFO99598.1 - 1.3e-08 34.4 7.0 1.7e-08 34.0 1.8 2.3 2 0 0 2 2 2 1 SNARE domain GRAM PF02893.15 KFO99598.1 - 0.0018 17.7 0.0 0.0037 16.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain V-SNARE_C PF12352.3 KFO99598.1 - 0.1 12.7 2.1 6.3 6.9 0.0 2.7 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Cupin_8 PF13621.1 KFO99599.1 - 4.7e-23 81.9 1.9 7.5e-23 81.3 1.3 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KFO99599.1 - 4.2e-20 72.1 0.2 1.2e-19 70.5 0.2 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KFO99599.1 - 0.0061 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Shisa PF13908.1 KFO99600.1 - 0.0041 17.3 0.0 0.0045 17.1 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KFO99600.1 - 0.04 12.2 0.0 0.044 12.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E WBP-1 PF11669.3 KFO99600.1 - 0.05 13.6 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 UPF0239 PF06783.6 KFO99600.1 - 0.2 11.6 2.2 11 6.0 1.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0239) EF-hand_6 PF13405.1 KFO99602.1 - 8.5e-09 34.5 0.1 0.012 15.4 0.0 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KFO99602.1 - 1.7e-06 28.0 0.4 3.4e-05 23.9 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFO99602.1 - 7.7e-06 24.8 2.5 0.026 13.8 0.0 4.7 5 1 1 6 6 6 2 EF hand EF-hand_8 PF13833.1 KFO99602.1 - 0.0052 16.3 1.8 0.93 9.1 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair DUF3734 PF12536.3 KFO99602.1 - 0.022 14.8 0.0 0.85 9.7 0.0 2.7 2 1 1 3 3 3 0 Patatin phospholipase 7tm_2 PF00002.19 KFO99604.1 - 2.9e-84 281.9 14.2 3.5e-84 281.7 9.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFO99604.1 - 1e-18 67.0 2.4 2e-18 66.1 1.7 1.5 1 0 0 1 1 1 1 Hormone receptor domain Inositol_P PF00459.20 KFO99605.1 - 4.3e-34 118.0 0.5 5.3e-34 117.7 0.3 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RuvA_N PF01330.16 KFO99605.1 - 0.1 12.3 0.1 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 RuvA N terminal domain Yae1_N PF09811.4 KFO99606.1 - 1.2e-13 50.3 42.5 0.13 11.8 1.9 4.3 2 1 0 2 2 2 2 Essential protein Yae1, N terminal FAM110_N PF14161.1 KFO99607.1 - 1.3e-52 176.5 5.4 1.3e-52 176.5 3.7 2.1 2 0 0 2 2 2 1 Centrosome-associated N terminus FAM110_C PF14160.1 KFO99607.1 - 2.4e-47 160.5 1.5 2.4e-47 160.5 1.1 2.2 3 0 0 3 3 3 1 Centrosome-associated C terminus SEP PF08059.8 KFO99608.1 - 7.4e-30 103.0 0.5 1.7e-29 101.9 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KFO99608.1 - 3.1e-18 65.6 0.2 4.9e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 KFO99608.1 - 0.0026 17.1 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Spt20 family p450 PF00067.17 KFO99609.1 - 1.1e-77 261.5 0.5 1.4e-77 261.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 PDZ PF00595.19 KFO99611.1 - 4.3e-21 74.8 2.3 4.9e-13 49.0 0.1 2.8 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFO99611.1 - 1.3e-11 44.1 0.3 5e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Beach PF02138.13 KFO99612.1 - 4.5e-103 344.3 0.0 7.4e-103 343.6 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 KFO99612.1 - 5.1e-25 86.3 16.7 2.1e-06 27.4 0.6 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat GRAM PF02893.15 KFO99612.1 - 3.7e-10 39.1 0.2 3.9e-09 35.8 0.0 2.8 3 0 0 3 3 3 1 GRAM domain PH_BEACH PF14844.1 KFO99612.1 - 9.2e-10 38.3 0.0 3.4e-06 26.8 0.0 3.5 2 1 0 2 2 2 2 PH domain associated with Beige/BEACH HMG_box PF00505.14 KFO99613.1 - 5.9e-18 64.8 0.5 1.3e-17 63.8 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFO99613.1 - 3.7e-12 46.4 0.8 6.7e-12 45.6 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 KFO99613.1 - 1.9 8.7 7.6 0.24 11.6 0.5 2.6 2 1 1 3 3 3 0 YABBY protein Carb_anhydrase PF00194.16 KFO99614.1 - 9.6e-97 322.9 0.0 1.1e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ras PF00071.17 KFO99616.1 - 1.8e-57 193.2 0.0 2.1e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFO99616.1 - 9.9e-17 61.5 0.0 1.9e-16 60.6 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFO99616.1 - 4.9e-12 45.4 0.0 5.5e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFO99616.1 - 0.0002 20.5 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFO99616.1 - 0.00058 19.3 0.0 0.00075 18.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CRAL_TRIO PF00650.15 KFO99617.1 - 1.5e-34 118.8 0.0 2.3e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFO99617.1 - 1.7e-09 37.6 0.1 4.7e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFO99617.1 - 1.4e-07 31.5 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Asp_Arg_Hydrox PF05118.10 KFO99618.1 - 3.1e-61 205.9 0.2 5.2e-61 205.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Asp-B-Hydro_N PF05279.6 KFO99618.1 - 3.3e-48 164.6 0.0 3.3e-48 164.6 0.0 2.2 1 1 1 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region TPR_11 PF13414.1 KFO99618.1 - 2.9e-14 52.4 0.0 0.0033 17.0 0.0 3.9 3 0 0 3 3 3 3 TPR repeat TPR_16 PF13432.1 KFO99618.1 - 3.6e-10 40.2 0.3 1.7e-05 25.3 0.6 4.1 2 1 4 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO99618.1 - 5.9e-09 35.8 3.9 0.0085 16.4 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFO99618.1 - 3.4e-07 29.6 4.0 0.33 10.9 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO99618.1 - 3.4e-07 30.3 0.0 0.0053 17.2 0.2 4.8 3 1 3 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO99618.1 - 8.4e-06 26.0 0.0 0.025 14.8 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFO99618.1 - 3e-05 23.4 2.2 0.6 10.0 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFO99618.1 - 7.1e-05 22.2 0.5 1 9.1 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFO99618.1 - 0.00017 21.4 2.2 2.9 7.9 0.1 4.4 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFO99618.1 - 0.0016 18.5 3.4 8 6.9 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat YfiO PF13525.1 KFO99618.1 - 0.016 14.7 0.3 0.1 12.0 0.1 2.3 3 0 0 3 3 3 0 Outer membrane lipoprotein LUC7 PF03194.10 KFO99618.1 - 0.02 14.4 0.5 0.035 13.6 0.3 1.3 1 0 0 1 1 1 0 LUC7 N_terminus UFC1 PF08694.6 KFO99618.1 - 0.038 13.4 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 TPR_9 PF13371.1 KFO99618.1 - 0.095 12.5 0.0 23 4.9 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat NKAIN PF05640.9 KFO99621.1 - 1.2e-73 246.4 5.5 1.3e-73 246.2 3.8 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.6 KFO99621.1 - 0.023 14.5 0.3 0.031 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Peptidase_C26 PF07722.8 KFO99622.1 - 4.5e-42 143.9 0.0 6e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 KFO99622.1 - 2e-09 37.2 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CRAL_TRIO PF00650.15 KFO99623.1 - 1.5e-33 115.5 0.0 2e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain NARG2_C PF10505.4 KFO99623.1 - 0.0084 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus YTH PF04146.10 KFO99624.1 - 1.1e-47 161.1 0.1 1.6e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain PAT1 PF09770.4 KFO99624.1 - 9 4.3 26.8 13 3.8 18.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 p450 PF00067.17 KFO99625.1 - 3.2e-52 177.6 0.4 4e-52 177.2 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arm PF00514.18 KFO99627.1 - 2.3e-05 24.0 0.0 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HMA PF00403.21 KFO99627.1 - 0.0023 18.0 0.3 0.0048 17.0 0.2 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain HEAT_2 PF13646.1 KFO99627.1 - 0.062 13.5 0.1 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats Mito_fiss_reg PF05308.6 KFO99628.1 - 4.1e-79 265.5 8.3 6.9e-79 264.7 5.8 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator FlxA PF14282.1 KFO99628.1 - 0.0068 16.3 1.7 0.0068 16.3 1.2 1.8 2 0 0 2 2 2 1 FlxA-like protein DnaJ PF00226.26 KFO99629.1 - 3.7e-26 90.6 2.9 5.8e-26 90.0 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain Corona_S2 PF01601.11 KFO99629.1 - 0.022 12.8 2.0 0.026 12.6 1.4 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein GP41 PF00517.12 KFO99629.1 - 0.035 13.6 0.0 0.062 12.8 0.0 1.4 2 0 0 2 2 2 0 Retroviral envelope protein CCER1 PF15482.1 KFO99629.1 - 0.12 11.9 0.8 0.13 11.8 0.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 zf-C3HC4_2 PF13923.1 KFO99630.1 - 7e-10 38.7 5.2 7e-10 38.7 3.6 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFO99630.1 - 5.9e-09 35.5 4.4 8.1e-09 35.0 1.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFO99630.1 - 2e-08 33.9 4.7 2e-08 33.9 3.3 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO99630.1 - 5e-08 32.4 4.2 5e-08 32.4 2.9 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO99630.1 - 5.4e-08 32.3 3.5 5.4e-08 32.3 2.4 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO99630.1 - 7.7e-07 28.7 4.7 7.7e-07 28.7 3.3 2.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFO99630.1 - 1.3e-05 24.9 7.3 1.3e-05 24.9 5.0 3.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFO99630.1 - 2.3e-05 24.0 0.4 2.3e-05 24.0 0.3 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-B_box PF00643.19 KFO99630.1 - 3.2e-05 23.7 9.5 3.2e-05 23.7 6.6 3.8 4 0 0 4 4 4 1 B-box zinc finger Flagellin_C PF00700.16 KFO99630.1 - 0.028 14.5 0.2 0.14 12.3 0.1 2.2 1 1 0 1 1 1 0 Bacterial flagellin C-terminal helical region bZIP_1 PF00170.16 KFO99630.1 - 0.28 11.1 3.3 7.9 6.5 0.0 2.8 1 1 1 2 2 2 0 bZIP transcription factor CRF PF00473.12 KFO99631.1 - 2.1e-17 62.9 1.1 4.5e-17 61.8 0.7 1.6 1 0 0 1 1 1 1 Corticotropin-releasing factor family UCN2 PF11613.3 KFO99631.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 Elongin_A PF06881.6 KFO99631.1 - 0.022 15.1 0.1 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Collagen PF01391.13 KFO99632.1 - 6e-11 41.7 22.7 6e-11 41.7 15.7 2.2 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFO99633.1 - 1.8e-52 177.8 0.0 2e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Sarcoglycan_2 PF05510.8 KFO99634.1 - 2.4e-33 115.0 0.0 3.6e-24 84.7 0.0 2.0 1 1 1 2 2 2 2 Sarcoglycan alpha/epsilon BCDHK_Adom3 PF10436.4 KFO99635.1 - 5.4e-27 94.3 0.0 7.9e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFO99635.1 - 6.7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DLL_N PF12413.3 KFO99636.1 - 1e-22 80.9 16.8 1e-22 80.9 11.7 1.6 2 0 0 2 2 2 1 Homeobox protein distal-less-like N terminal Homeobox PF00046.24 KFO99636.1 - 3.3e-18 65.0 2.8 5.3e-18 64.3 1.9 1.3 1 0 0 1 1 1 1 Homeobox domain MOZ_SAS PF01853.13 KFO99638.1 - 2e-89 297.8 2.4 2.9e-89 297.3 1.7 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-C2HC PF01530.13 KFO99638.1 - 1.9e-06 27.4 1.1 1.9e-06 27.4 0.7 1.8 2 0 0 2 2 2 1 Zinc finger, C2HC type HTH_Tnp_IS630 PF01710.11 KFO99638.1 - 0.013 15.1 0.5 0.33 10.6 0.1 2.4 2 0 0 2 2 2 0 Transposase zf-met PF12874.2 KFO99638.1 - 0.04 14.1 0.4 0.11 12.6 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type FAM117 PF15388.1 KFO99639.1 - 2.6e-109 365.3 7.1 3.2e-109 365.0 4.9 1.0 1 0 0 1 1 1 1 Protein Family FAM117 CSTF_C PF14304.1 KFO99639.1 - 0.09 12.0 0.5 0.2 10.9 0.4 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal UAA PF08449.6 KFO99640.1 - 1.4e-78 263.8 8.9 1.8e-78 263.5 6.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFO99640.1 - 1e-15 57.8 20.7 4.7e-09 36.3 7.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KFO99640.1 - 2.9e-13 49.7 16.5 2.5e-11 43.4 6.5 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KFO99640.1 - 6.6e-10 39.1 20.3 3.9e-06 27.0 1.3 2.1 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 KFO99640.1 - 0.023 13.7 3.1 2 7.4 0.0 2.6 3 0 0 3 3 3 0 Nucleotide-sugar transporter BTB PF00651.26 KFO99641.1 - 1.9e-26 92.1 0.0 2.9e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.21 KFO99641.1 - 2.7e-10 40.5 0.0 3.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 MATH domain OATP PF03137.15 KFO99642.1 - 5.2e-173 575.9 2.6 1.8e-170 567.6 1.8 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFO99642.1 - 3e-19 68.9 33.1 5.5e-14 51.6 10.8 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily zf-RING_2 PF13639.1 KFO99644.1 - 0.0049 16.6 1.1 0.28 11.0 0.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-Di19 PF05605.7 KFO99644.1 - 0.028 14.5 0.3 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cys_rich_CPXG PF14255.1 KFO99644.1 - 0.21 11.4 2.4 4.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG DZR PF12773.2 KFO99644.1 - 0.6 9.9 2.3 4 7.3 1.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon YlaH PF14036.1 KFO99644.1 - 1.4 9.0 9.5 0.16 12.0 2.7 2.2 1 1 1 2 2 2 0 YlaH-like protein CI-B14_5a PF07347.7 KFO99645.1 - 0.056 13.2 1.1 0.1 12.3 0.7 1.6 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Cadherin PF00028.12 KFO99646.1 - 1.1e-14 54.4 0.0 3.5e-13 49.6 0.0 2.0 2 0 0 2 2 2 2 Cadherin domain MAM PF00629.18 KFO99649.1 - 1.8e-52 177.3 0.0 3.3e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 MAM domain I-set PF07679.11 KFO99649.1 - 4.7e-43 144.9 0.0 1.2e-11 44.3 0.0 5.4 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99649.1 - 9.3e-38 128.2 2.5 4.4e-09 36.3 0.0 5.7 6 0 0 6 6 6 4 Immunoglobulin domain Ig_3 PF13927.1 KFO99649.1 - 3.7e-35 120.2 0.9 5.5e-08 33.1 0.0 5.0 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.20 KFO99649.1 - 1.7e-25 88.9 0.4 8.5e-06 25.8 0.0 5.6 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 KFO99649.1 - 9.5e-21 73.8 7.7 6.2e-05 22.8 0.0 7.8 5 3 0 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO99649.1 - 5.8e-12 45.3 0.2 0.0013 18.5 0.0 4.6 4 0 0 4 4 4 4 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFO99649.1 - 0.016 15.1 2.0 0.32 11.0 0.0 3.6 5 0 0 5 5 5 0 Immunoglobulin C1-set domain BiPBP_C PF06832.7 KFO99649.1 - 0.11 12.4 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family SANTA PF09133.5 KFO99650.1 - 6.4e-23 80.5 0.0 7.1e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 SANTA (SANT Associated) Myb_DNA-bind_6 PF13921.1 KFO99651.1 - 0.02 14.9 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFO99651.1 - 0.028 14.4 0.0 0.077 13.0 0.0 1.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain Helicase_C PF00271.26 KFO99652.1 - 3.8e-18 65.1 0.2 1.3e-17 63.3 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC4 PF02732.10 KFO99652.1 - 1.2e-09 38.0 0.2 3e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 ERCC4 domain DEAD PF00270.24 KFO99652.1 - 3.2e-06 26.7 0.0 1.2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFO99652.1 - 0.0004 20.2 0.1 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_2 PF12826.2 KFO99652.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif SOUL PF04832.7 KFO99653.1 - 1.5e-41 141.8 0.0 1.7e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein FKBP_C PF00254.23 KFO99654.1 - 1.1e-12 47.7 0.1 1.3e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase CLASP_N PF12348.3 KFO99655.1 - 3.3e-09 36.4 1.5 1.2e-05 24.7 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT_2 PF13646.1 KFO99655.1 - 0.00054 20.1 3.0 0.35 11.1 0.5 3.9 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KFO99655.1 - 0.0073 16.3 5.7 4 7.7 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat ParcG PF10274.4 KFO99655.1 - 0.018 14.9 0.9 0.24 11.3 0.3 2.4 2 1 0 2 2 2 0 Parkin co-regulated protein Adaptin_N PF01602.15 KFO99655.1 - 0.11 10.8 3.6 0.09 11.0 0.3 2.3 3 0 0 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.1 KFO99655.1 - 0.19 12.2 2.3 0.97 10.0 1.6 2.4 1 0 0 1 1 1 0 HEAT-like repeat C2 PF00168.25 KFO99656.1 - 5.9e-09 35.6 0.1 8.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain PH PF00169.24 KFO99656.1 - 0.022 14.9 0.6 2.6 8.3 0.0 2.7 2 1 0 2 2 2 0 PH domain PH_6 PF15406.1 KFO99656.1 - 0.057 13.4 0.1 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Anillin PF08174.6 KFO99656.1 - 0.1 12.6 0.1 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Cell division protein anillin TSP_3 PF02412.13 KFO99657.1 - 5.8e-58 192.0 138.2 5.4e-12 44.9 10.7 10.4 8 2 2 10 10 10 8 Thrombospondin type 3 repeat TSP_1 PF00090.14 KFO99657.1 - 1.3e-44 150.0 56.6 2.6e-16 59.4 6.3 5.0 4 0 0 4 4 4 3 Thrombospondin type 1 domain VWC PF00093.13 KFO99657.1 - 1.5e-13 50.6 17.9 1.5e-13 50.6 12.4 6.2 5 1 0 5 5 5 1 von Willebrand factor type C domain TSP_C PF05735.7 KFO99657.1 - 1.3e-07 31.3 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Thrombospondin C-terminal region EGF_3 PF12947.2 KFO99657.1 - 1.7e-07 31.0 7.1 1.7e-07 31.0 4.9 6.1 5 0 0 5 5 5 2 EGF domain EGF_CA PF07645.10 KFO99657.1 - 3.2e-06 27.0 1.7 3.2e-06 27.0 1.2 5.7 5 1 0 5 5 5 3 Calcium-binding EGF domain EGF PF00008.22 KFO99657.1 - 0.00077 19.3 5.6 0.00077 19.3 3.9 4.7 3 0 0 3 3 3 1 EGF-like domain DUF1387 PF07139.6 KFO99661.1 - 9.3e-119 396.5 8.8 1e-118 396.3 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) CENP-K PF11802.3 KFO99661.1 - 0.29 10.3 5.0 0.83 8.8 3.5 1.7 1 1 0 1 1 1 0 Centromere-associated protein K YbjQ_1 PF01906.12 KFO99661.1 - 0.57 10.6 2.9 9.6 6.6 2.0 2.2 1 1 0 1 1 1 0 Putative heavy-metal-binding Syntaxin-6_N PF09177.6 KFO99661.1 - 0.6 10.5 5.2 0.3 11.5 0.9 2.6 3 1 0 3 3 3 0 Syntaxin 6, N-terminal ALMT PF11744.3 KFO99661.1 - 0.8 8.2 4.7 1.1 7.8 3.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Toxin_4 PF00706.12 KFO99662.1 - 0.052 13.7 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Anenome neurotoxin Tubulin PF00091.20 KFO99663.1 - 2.8e-44 151.5 0.0 3.5e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFO99663.1 - 7.1e-14 51.9 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFO99663.1 - 0.00073 19.0 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Hormone_recep PF00104.25 KFO99664.1 - 8.6e-16 57.6 0.0 9.2e-16 57.5 0.0 1.0 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor CBS PF00571.23 KFO99665.1 - 1.5e-26 91.8 0.1 6.9e-10 38.5 0.0 3.7 4 0 0 4 4 4 3 CBS domain GARS_C PF02843.11 KFO99665.1 - 0.045 13.9 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Arf PF00025.16 KFO99666.1 - 1e-30 106.2 0.5 1.2e-30 106.0 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFO99666.1 - 6.1e-06 25.5 0.1 6.7e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFO99666.1 - 1.3e-05 24.5 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KFO99666.1 - 3.9e-05 23.1 0.2 4.6e-05 22.8 0.2 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFO99666.1 - 0.0001 21.1 0.8 0.073 11.7 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KFO99666.1 - 0.0021 18.5 0.1 0.0027 18.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein 6PF2K PF01591.13 KFO99666.1 - 0.0024 16.9 0.2 0.0026 16.8 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 KFO99666.1 - 0.053 13.3 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KFO99666.1 - 0.078 12.9 0.2 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 KFO99666.1 - 0.096 12.1 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FKBP_C PF00254.23 KFO99667.1 - 7.4e-13 48.3 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TMEMspv1-c74-12 PF11044.3 KFO99667.1 - 0.032 13.7 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cyclin_N PF00134.18 KFO99668.1 - 1.6e-16 59.9 1.4 1.9e-13 50.0 0.2 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain UPF0253 PF06786.7 KFO99668.1 - 0.082 13.0 0.2 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) zf-C3Hc3H PF13891.1 KFO99669.1 - 9.7e-17 60.8 4.9 2e-16 59.7 3.4 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.3 KFO99669.1 - 0.027 13.8 12.3 0.25 10.7 0.1 3.5 3 1 0 3 3 3 0 CCCH zinc finger in TRM13 protein zf-C3Hc3H PF13891.1 KFO99670.1 - 2.2e-17 62.8 7.7 3.2e-17 62.3 5.3 1.2 1 0 0 1 1 1 1 Potential DNA-binding domain DUF1649 PF07855.7 KFO99671.1 - 1.6e-52 177.4 0.1 2.1e-52 177.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) tRNA_lig_CPD PF08302.6 KFO99671.1 - 0.037 13.2 0.8 0.84 8.7 0.0 2.4 3 0 0 3 3 3 0 Fungal tRNA ligase phosphodiesterase domain Pro_3_hydrox_C PF05373.6 KFO99671.1 - 0.07 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Pkinase PF00069.20 KFO99672.1 - 5.3e-53 179.8 0.0 9.2e-53 179.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99672.1 - 5.3e-37 127.2 0.0 4.2e-36 124.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFO99672.1 - 5.9e-15 54.2 0.1 1.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif APH PF01636.18 KFO99672.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 KFO99673.1 - 1.4e-17 63.7 0.1 1.3e-09 38.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFO99673.1 - 2e-16 58.8 0.3 1.8e-05 24.3 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFO99673.1 - 5e-15 55.1 2.1 3.9e-07 30.1 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFO99673.1 - 2.4e-13 50.2 0.1 1.6e-06 28.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFO99673.1 - 1.1e-11 43.7 0.1 4.1e-05 23.4 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat CENP-F_C_Rb_bdg PF10490.4 KFO99673.1 - 0.0071 15.6 0.0 1.8 7.9 0.0 2.6 2 0 0 2 2 2 2 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Plasmid_RAQPRD PF09686.5 KFO99674.1 - 0.07 13.2 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Methyltransf_11 PF08241.7 KFO99675.1 - 9.8e-16 58.0 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFO99675.1 - 2.9e-13 49.8 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFO99675.1 - 2.7e-12 47.0 0.0 5.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFO99675.1 - 1.5e-10 40.9 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO99675.1 - 1e-07 32.5 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFO99675.1 - 1.2e-07 31.0 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFO99675.1 - 1.2e-06 28.7 0.0 2.9e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFO99675.1 - 4.9e-06 26.5 0.0 9.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFO99675.1 - 5.7e-05 22.6 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_8 PF05148.10 KFO99675.1 - 0.00015 21.4 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Reovirus_L2 PF06016.6 KFO99675.1 - 0.055 10.4 0.0 0.067 10.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) MTS PF05175.9 KFO99675.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 KFO99675.1 - 0.14 13.0 0.0 0.38 11.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Trypsin PF00089.21 KFO99677.1 - 4.4e-69 232.4 0.0 4.9e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFO99677.1 - 0.00045 19.6 0.0 0.00066 19.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFO99677.1 - 0.0027 17.6 0.0 0.0049 16.8 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S6 PF02395.11 KFO99677.1 - 0.059 11.5 0.0 0.071 11.2 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease bZIP_1 PF00170.16 KFO99678.1 - 2.9e-22 78.3 8.7 4.7e-22 77.7 6.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor pKID PF02173.12 KFO99678.1 - 3e-17 61.5 5.7 3e-17 61.5 3.9 2.2 2 0 0 2 2 2 1 pKID domain bZIP_2 PF07716.10 KFO99678.1 - 5.4e-09 35.7 8.1 9.5e-09 34.9 5.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFO99678.1 - 0.00024 21.3 4.8 0.00052 20.2 3.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.6 KFO99678.1 - 0.021 14.1 1.0 0.035 13.4 0.7 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Acatn PF13000.2 KFO99678.1 - 0.047 12.2 0.8 0.062 11.8 0.6 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 tRNA-synt_1g PF09334.6 KFO99679.1 - 3.3e-142 473.7 0.0 4.2e-142 473.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 KFO99679.1 - 1.7e-17 62.8 6.0 3.1e-17 61.9 4.1 1.4 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 KFO99679.1 - 1.8e-08 32.8 0.0 0.00083 17.4 0.0 2.8 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFO99679.1 - 0.0062 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA GST_C_3 PF14497.1 KFO99679.1 - 0.012 16.0 0.3 0.12 12.8 0.0 2.9 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFO99679.1 - 0.12 12.2 0.9 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain bZIP_2 PF07716.10 KFO99680.1 - 0.0083 15.9 3.5 0.017 14.9 2.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFO99680.1 - 0.018 14.9 1.3 0.04 13.8 0.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF1192 PF06698.6 KFO99680.1 - 0.055 13.2 1.6 0.15 11.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DivIC PF04977.10 KFO99680.1 - 0.097 12.1 1.4 0.21 11.1 1.0 1.6 1 0 0 1 1 1 0 Septum formation initiator CP2 PF04516.10 KFO99681.1 - 1.9e-72 243.1 0.0 3.1e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor DAZAP2 PF11029.3 KFO99682.1 - 1.1e-27 97.1 5.8 1.3e-27 96.8 4.0 1.1 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) zf-H2C2_2 PF13465.1 KFO99683.1 - 2.8e-14 52.5 30.9 4.8e-08 32.9 2.4 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFO99683.1 - 3.5e-13 49.0 26.4 2e-05 24.6 0.5 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO99683.1 - 8.7e-10 38.2 25.0 0.00011 22.2 0.9 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO99683.1 - 0.0056 16.7 5.1 1.2 9.3 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 KFO99683.1 - 0.018 14.5 1.0 0.57 9.7 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_6 PF13912.1 KFO99683.1 - 0.044 13.7 8.8 0.43 10.5 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFO99683.1 - 8.6 6.5 13.4 2.2 8.4 1.6 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFO99684.1 - 8.7e-18 63.5 15.0 1.7e-06 27.9 3.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO99684.1 - 2.8e-15 55.7 19.2 2.4e-08 33.8 2.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO99684.1 - 1.8e-13 49.7 13.2 1.7e-05 24.8 1.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO99684.1 - 1.4e-07 31.4 6.6 0.012 15.7 1.3 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO99684.1 - 8.8e-05 22.5 5.2 0.1 12.8 0.8 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KFO99684.1 - 0.0014 18.2 3.0 0.83 9.3 0.2 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-BED PF02892.10 KFO99684.1 - 0.0078 15.9 13.8 0.044 13.5 3.3 3.2 2 1 1 3 3 3 1 BED zinc finger RRN7 PF11781.3 KFO99684.1 - 0.0095 15.4 0.9 1.1 8.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_6 PF13912.1 KFO99684.1 - 0.014 15.3 10.2 0.27 11.2 3.2 2.9 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFO99684.1 - 0.016 15.3 3.7 0.71 10.0 1.1 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 KFO99684.1 - 0.044 13.5 4.3 0.38 10.4 0.2 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-Di19 PF05605.7 KFO99684.1 - 0.2 11.8 5.6 0.28 11.3 2.0 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.7 KFO99684.1 - 0.29 11.3 2.1 0.33 11.1 1.5 1.4 1 1 0 1 1 1 0 CHY zinc finger zf-Sec23_Sec24 PF04810.10 KFO99684.1 - 0.3 10.6 2.1 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.5 KFO99684.1 - 2.3 8.2 4.0 3.3 7.7 0.1 2.5 3 0 0 3 3 3 0 Zinc ribbon domain ROS_MUCR PF05443.6 KFO99684.1 - 4.1 7.1 5.3 4.9 6.9 0.9 2.4 2 1 1 3 3 3 0 ROS/MUCR transcriptional regulator protein WD40 PF00400.27 KFO99685.1 - 2.6e-11 42.9 12.2 0.00011 21.9 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 KFO99685.1 - 3.5e-07 30.1 0.0 0.0093 15.6 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF4613 PF15390.1 KFO99685.1 - 0.00044 18.5 6.4 0.11 10.6 2.7 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4613) PD40 PF07676.7 KFO99685.1 - 0.0019 17.8 2.0 0.71 9.6 0.1 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Hormone_recep PF00104.25 KFO99686.1 - 8e-29 100.2 1.1 1.3e-28 99.5 0.7 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFO99686.1 - 1.7e-28 98.6 15.7 2.8e-28 97.9 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Bromodomain PF00439.20 KFO99687.1 - 7.9e-47 157.1 1.2 9.5e-24 83.1 0.1 2.4 2 0 0 2 2 2 2 Bromodomain Sigma70_ner PF04546.8 KFO99687.1 - 0.0016 18.0 15.2 0.0057 16.2 10.5 2.0 1 0 0 1 1 1 1 Sigma-70, non-essential region Astro_capsid PF03115.9 KFO99687.1 - 0.0091 14.3 3.0 0.014 13.7 2.1 1.2 1 0 0 1 1 1 1 Astrovirus capsid protein precursor Nop14 PF04147.7 KFO99687.1 - 0.55 8.0 27.2 0.03 12.2 14.5 1.9 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 KFO99687.1 - 1.2 7.1 23.0 2.1 6.3 16.0 1.3 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 KFO99687.1 - 1.5 6.9 10.4 2.2 6.3 7.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Allexi_40kDa PF05549.6 KFO99687.1 - 2.6 7.2 6.6 7.2 5.8 4.6 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein PTRF_SDPR PF15237.1 KFO99687.1 - 5.5 6.3 19.4 0.51 9.7 9.9 1.8 2 0 0 2 2 2 0 PTRF/SDPR family Pox_RNA_Pol_19 PF05320.7 KFO99687.1 - 6.5 6.4 12.7 18 5.0 8.8 1.7 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nucleoplasmin PF03066.10 KFO99687.1 - 7.5 6.0 18.5 12 5.3 11.5 2.2 2 0 0 2 2 2 0 Nucleoplasmin Rep_4 PF05797.6 KFO99687.1 - 8.8 4.9 9.6 18 3.8 6.6 1.5 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Hid1 PF12722.2 KFO99687.1 - 9.7 3.7 8.1 14 3.2 5.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein C1-set PF07654.10 KFO99688.1 - 3.1e-19 68.7 0.0 4.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFO99688.1 - 8.1e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFO99688.1 - 4.4e-05 23.5 0.0 7.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Ribosomal_S7 PF00177.16 KFO99689.1 - 1.1e-07 31.4 0.1 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.16 KFO99690.1 - 1e-17 64.0 0.4 1.1e-17 63.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e 7tm_3 PF00003.17 KFO99691.1 - 3.7e-21 75.5 0.1 1.3e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 KFO99691.1 - 1.7e-20 73.1 0.1 5.6e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region TctB PF07331.6 KFO99691.1 - 0.85 9.2 7.0 0.11 12.1 0.2 2.7 2 2 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Orbi_VP5 PF00901.12 KFO99691.1 - 1.1 7.3 5.8 1.6 6.8 4.1 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Tnp_P_element PF12017.3 KFO99691.1 - 1.9 7.6 4.3 3.2 6.9 2.9 1.3 1 0 0 1 1 1 0 Transposase protein SH3BP5 PF05276.9 KFO99692.1 - 1.3e-88 296.3 22.9 1.7e-88 295.9 15.9 1.1 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Tropomyosin_1 PF12718.2 KFO99692.1 - 0.0071 16.1 10.7 0.0071 16.1 7.4 2.5 2 1 0 2 2 2 1 Tropomyosin like FadA PF09403.5 KFO99692.1 - 0.011 15.6 6.2 0.011 15.6 4.3 2.2 1 1 1 2 2 2 0 Adhesion protein FadA LemA PF04011.7 KFO99692.1 - 0.054 12.5 7.9 0.014 14.4 2.3 2.1 2 1 0 2 2 2 0 LemA family OMS28_porin PF03532.8 KFO99692.1 - 0.064 12.3 2.3 0.11 11.6 1.6 1.4 1 0 0 1 1 1 0 OMS28 porin Hydrolase_3 PF08282.7 KFO99692.1 - 0.1 12.1 0.7 0.17 11.4 0.5 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3772 PF12607.3 KFO99692.1 - 0.83 9.3 7.4 0.067 12.8 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) TMF_TATA_bd PF12325.3 KFO99692.1 - 5 6.8 20.3 24 4.6 0.3 3.5 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HEAT_PBS PF03130.11 KFO99693.1 - 8 7.2 9.3 5 7.8 2.3 3.6 3 1 0 3 3 3 0 PBS lyase HEAT-like repeat HCV_core PF01542.13 KFO99693.1 - 8.2 6.8 9.1 19 5.6 0.2 3.5 1 1 3 4 4 4 0 Hepatitis C virus core protein zf-H2C2_2 PF13465.1 KFO99694.1 - 4.3e-74 241.4 79.6 2.7e-09 36.8 0.5 13.6 14 0 0 14 14 14 10 Zinc-finger double domain zf-C2H2 PF00096.21 KFO99694.1 - 1.2e-68 223.4 82.7 2.3e-07 30.7 2.8 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO99694.1 - 8.4e-37 122.8 67.6 9.1e-05 22.5 1.2 12.2 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFO99694.1 - 9.2e-30 101.6 71.1 8.7e-06 25.4 0.1 12.6 12 1 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO99694.1 - 1.9e-12 46.9 36.9 0.055 13.6 0.0 11.3 12 0 0 12 12 11 2 Zinc-finger double-stranded RNA-binding DNA_RNApol_7kD PF03604.8 KFO99694.1 - 7.8e-06 25.2 53.8 0.46 10.0 0.1 12.0 12 0 0 12 12 12 6 DNA directed RNA polymerase, 7 kDa subunit XPA_N PF01286.13 KFO99694.1 - 8.2e-06 25.4 59.6 2.7 7.7 0.1 12.0 13 0 0 13 13 12 8 XPA protein N-terminal C1_4 PF07975.7 KFO99694.1 - 7.8e-05 22.5 40.9 0.27 11.2 0.3 8.5 2 2 6 9 9 9 4 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 KFO99694.1 - 0.00057 19.7 70.2 1.2 9.1 3.4 11.3 7 5 4 11 11 11 5 Zinc ribbon domain zf-trcl PF13451.1 KFO99694.1 - 0.026 14.1 51.7 3.7 7.2 0.0 11.5 11 2 0 11 11 11 0 Probable zinc-binding domain BolA PF01722.13 KFO99694.1 - 0.17 11.8 11.3 10 6.1 1.0 4.8 4 1 0 4 4 4 0 BolA-like protein zf-Di19 PF05605.7 KFO99694.1 - 0.2 11.8 0.2 0.2 11.8 0.2 5.9 6 1 0 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.1 KFO99694.1 - 0.75 10.1 70.4 2.8 8.2 2.7 10.0 4 2 5 9 9 8 0 Recombinase zinc beta ribbon domain DUF1163 PF06651.6 KFO99694.1 - 9.4 5.8 7.7 9.2 5.8 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1163) zf-H2C2_2 PF13465.1 KFO99695.1 - 2.2e-11 43.4 6.3 3.3e-08 33.4 0.5 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFO99695.1 - 7.1e-09 35.4 5.7 1e-07 31.8 1.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFO99695.1 - 0.00052 20.1 1.2 0.00052 20.1 0.9 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger DUF2256 PF10013.4 KFO99695.1 - 0.012 15.3 0.2 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.5 KFO99695.1 - 0.091 12.7 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc ribbon domain zf-trcl PF13451.1 KFO99695.1 - 0.093 12.3 0.1 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Probable zinc-binding domain zf-C2H2_6 PF13912.1 KFO99695.1 - 0.21 11.5 0.3 0.21 11.5 0.2 2.3 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFO99695.1 - 3.8 7.9 8.0 14 6.1 2.1 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFO99696.1 - 1.4e-52 172.9 64.5 2.8e-07 30.4 0.9 9.1 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO99696.1 - 1.6e-50 167.0 65.6 8.7e-08 32.0 0.2 10.6 10 1 0 10 10 10 8 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFO99696.1 - 3e-31 106.3 52.0 2.1e-05 24.2 0.2 9.2 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFO99696.1 - 3.3e-31 105.2 62.2 0.0001 22.3 1.2 9.1 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO99696.1 - 2.3e-11 43.4 28.4 0.51 10.5 0.0 9.4 9 1 0 9 9 9 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFO99696.1 - 4.3e-06 26.5 44.3 0.75 9.7 0.1 8.8 7 1 1 8 8 8 4 Zinc ribbon domain XPA_N PF01286.13 KFO99696.1 - 2.5e-05 23.8 30.7 0.39 10.4 0.0 8.5 9 0 0 9 9 9 1 XPA protein N-terminal C1_4 PF07975.7 KFO99696.1 - 6.7e-05 22.8 23.3 0.37 10.8 0.9 7.0 1 1 7 8 8 8 1 TFIIH C1-like domain FYDLN_acid PF09538.5 KFO99696.1 - 0.0016 18.9 6.9 1.5 9.4 0.0 5.9 4 2 3 7 7 6 1 Protein of unknown function (FYDLN_acid) zf-LYAR PF08790.6 KFO99696.1 - 0.002 17.7 27.0 6.2 6.6 0.0 8.8 9 1 0 9 9 9 0 LYAR-type C2HC zinc finger zf-CHY PF05495.7 KFO99696.1 - 0.0048 17.0 22.3 0.54 10.4 1.8 4.7 1 1 3 4 4 4 2 CHY zinc finger LIM PF00412.17 KFO99696.1 - 0.0078 16.2 24.7 1.7 8.7 0.4 7.2 5 4 0 5 5 5 2 LIM domain zf-trcl PF13451.1 KFO99696.1 - 0.0087 15.6 35.5 1.6 8.4 0.0 8.0 8 1 0 8 8 8 2 Probable zinc-binding domain zf-met PF12874.2 KFO99696.1 - 0.015 15.4 37.1 1.9 8.7 0.0 8.3 9 0 0 9 9 8 0 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.8 KFO99696.1 - 0.062 12.7 36.1 2.7 7.5 0.2 8.3 9 0 0 9 9 9 0 DNA directed RNA polymerase, 7 kDa subunit DUF2256 PF10013.4 KFO99696.1 - 0.067 12.9 0.5 0.067 12.9 0.4 7.8 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-AN1 PF01428.11 KFO99696.1 - 0.078 12.8 46.3 3.2 7.6 0.3 9.2 6 3 3 9 9 9 0 AN1-like Zinc finger RRN7 PF11781.3 KFO99696.1 - 0.091 12.2 0.1 0.091 12.2 0.1 6.2 8 0 0 8 8 7 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Di19 PF05605.7 KFO99696.1 - 0.16 12.1 0.2 0.16 12.1 0.1 5.3 6 1 1 7 7 5 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.14 KFO99696.1 - 0.21 11.3 21.5 3.1 7.5 0.2 5.0 1 1 4 5 5 5 0 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 KFO99696.1 - 0.23 11.0 28.5 5.9 6.6 0.0 8.6 9 0 0 9 9 9 0 Transcription factor S-II (TFIIS) GAGA PF09237.6 KFO99696.1 - 0.27 10.8 3.1 4.5 6.9 0.1 2.7 2 0 0 2 2 2 0 GAGA factor BolA PF01722.13 KFO99696.1 - 0.36 10.8 5.5 7.3 6.6 0.0 3.8 3 2 1 4 4 4 0 BolA-like protein Yippee-Mis18 PF03226.9 KFO99696.1 - 1.5 8.9 19.4 18 5.4 0.1 6.1 4 3 1 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.1 KFO99696.1 - 3.8 7.2 30.0 23 4.8 0.0 8.5 9 0 0 9 9 9 0 zinc-ribbon domain Tmemb_55A PF09788.4 KFO99696.1 - 5.5 6.0 12.2 1.8 7.6 0.5 3.5 2 1 1 3 3 3 0 Transmembrane protein 55A RVT_1 PF00078.22 KFO99698.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.2 KFO99699.1 - 4.9e-92 302.4 17.0 8.2e-16 58.1 0.0 8.1 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFO99699.1 - 4.3e-85 275.5 20.7 1.9e-09 36.8 0.0 15.0 15 0 0 15 15 15 14 Ankyrin repeat Ank_3 PF13606.1 KFO99699.1 - 2e-69 222.5 19.4 6.8e-06 25.8 0.0 16.3 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 KFO99699.1 - 3.8e-65 215.2 14.2 7.6e-10 39.0 0.1 10.2 6 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO99699.1 - 2.2e-63 208.8 13.5 4.6e-08 33.0 0.0 13.4 3 3 10 13 13 13 13 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFO99699.1 - 1.3e-08 34.3 24.5 2.5e-08 33.3 17.0 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 KFO99699.1 - 3.3e-05 22.4 18.4 0.0057 15.1 8.3 2.2 1 1 1 2 2 2 2 Polycystin cation channel DUF1843 PF08898.5 KFO99699.1 - 0.13 12.3 0.4 10 6.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) TRF PF08558.5 KFO99700.1 - 9.3e-28 97.1 3.5 1.6e-27 96.4 2.4 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KFO99700.1 - 8.2e-10 38.5 0.5 2e-09 37.3 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFO99700.1 - 5.2e-05 23.2 0.9 0.00034 20.6 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain TPR_7 PF13176.1 KFO99700.1 - 0.033 13.9 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFO99700.1 - 0.034 14.7 0.0 0.11 13.2 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TSP_1 PF00090.14 KFO99701.1 - 0.00022 21.2 2.5 0.00022 21.2 1.7 2.7 2 1 0 2 2 2 1 Thrombospondin type 1 domain Ribosomal_L30_N PF08079.7 KFO99703.1 - 1.3e-24 86.0 18.0 2.3e-24 85.2 12.5 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KFO99703.1 - 6.1e-22 76.9 0.9 1.6e-21 75.5 0.6 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e dsrm PF00035.20 KFO99704.1 - 1e-51 173.3 2.0 3.3e-13 50.0 0.0 4.8 4 0 0 4 4 4 4 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFO99704.1 - 3.2e-10 40.1 4.0 0.0016 18.6 0.0 5.0 4 2 0 4 4 4 3 double strand RNA binding domain from DEAD END PROTEIN 1 UQ_con PF00179.21 KFO99705.1 - 3.7e-34 117.1 0.2 4e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFO99705.1 - 2.8e-05 23.8 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFO99705.1 - 0.0078 15.8 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KFO99705.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain Skp1_POZ PF03931.10 KFO99706.1 - 1.7e-23 82.5 0.0 2.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF1301 PF06979.7 KFO99707.1 - 1.3e-65 219.5 8.5 1.6e-65 219.2 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1301) E1_DerP2_DerF2 PF02221.10 KFO99708.1 - 6.8e-09 36.0 0.0 7.9e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 ML domain GST_N_3 PF13417.1 KFO99709.1 - 3e-12 46.5 0.0 5.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFO99709.1 - 4.1e-10 39.7 0.0 8.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFO99709.1 - 1.1e-09 38.0 0.0 2.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFO99709.1 - 3.4e-08 33.3 0.0 6.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFO99709.1 - 8.8e-08 32.0 0.0 2.1e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFO99709.1 - 0.00013 22.4 0.1 0.00026 21.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1617 PF07761.7 KFO99709.1 - 0.028 14.4 1.2 0.053 13.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Med30 PF11315.3 KFO99709.1 - 0.035 14.2 2.4 0.15 12.2 1.5 1.9 1 1 0 1 1 1 0 Mediator complex subunit 30 DUF2096 PF09869.4 KFO99709.1 - 0.036 13.9 1.9 0.29 10.9 0.3 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) DUF3206 PF11472.3 KFO99709.1 - 0.037 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) MtrG PF04210.8 KFO99709.1 - 0.11 12.1 0.6 0.26 10.9 0.4 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G MCR_C PF04609.7 KFO99709.1 - 0.12 11.1 0.2 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Prefoldin PF02996.12 KFO99709.1 - 3.3 7.3 6.5 5.2 6.7 0.8 2.4 1 1 1 2 2 2 0 Prefoldin subunit CCDC-167 PF15188.1 KFO99709.1 - 9.6 6.2 8.1 18 5.3 0.1 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 UNC119_bdg PF15435.1 KFO99710.1 - 4e-94 313.4 1.0 4.5e-94 313.3 0.7 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue SpoU_methylase PF00588.14 KFO99711.1 - 1.2e-30 106.2 0.0 1.7e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KFO99711.1 - 1.7e-12 47.3 0.0 2.7e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF4177 PF13783.1 KFO99711.1 - 0.026 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) adh_short PF00106.20 KFO99712.1 - 1.5e-27 96.5 0.1 2e-27 96.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFO99712.1 - 5.3e-14 52.5 0.0 6.8e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFO99712.1 - 3e-10 40.0 0.2 7.6e-10 38.7 0.1 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KFO99712.1 - 4.4e-05 23.5 0.1 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFO99712.1 - 0.00045 19.7 0.2 0.0015 17.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KFO99712.1 - 0.0012 19.2 0.0 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 KFO99712.1 - 0.0017 18.0 0.4 0.0036 17.0 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KFO99712.1 - 0.0038 17.3 0.3 0.012 15.7 0.1 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KFO99712.1 - 0.0068 15.6 0.1 0.048 12.9 0.0 2.1 2 1 1 3 3 3 1 NmrA-like family Saccharop_dh PF03435.13 KFO99712.1 - 0.013 14.5 0.1 0.025 13.5 0.1 1.4 1 1 1 2 2 2 0 Saccharopine dehydrogenase DUF1168 PF06658.7 KFO99713.1 - 8.5 5.8 24.9 0.21 11.1 3.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1168) GWT1 PF06423.7 KFO99714.1 - 4.7e-34 117.3 1.6 4.7e-34 117.3 1.1 2.1 2 0 0 2 2 2 1 GWT1 Myosin_head PF00063.16 KFO99715.1 - 6.5e-189 629.3 0.0 7.9e-189 629.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFO99715.1 - 5.4e-05 22.4 10.7 0.0012 18.2 0.7 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KFO99715.1 - 0.00056 20.0 0.5 0.006 16.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFO99715.1 - 0.0009 19.2 0.0 0.17 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain ParcG PF10274.4 KFO99716.1 - 0.01 15.7 0.0 0.011 15.6 0.0 1.0 1 0 0 1 1 1 0 Parkin co-regulated protein 7tm_1 PF00001.16 KFO99717.1 - 6.2e-32 110.7 20.1 7e-32 110.5 14.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2418 PF10332.4 KFO99717.1 - 6.3 7.1 6.9 1.6 9.1 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) Carb_anhydrase PF00194.16 KFO99718.1 - 2.2e-71 239.8 0.1 2.6e-71 239.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase GSG-1 PF07803.6 KFO99718.1 - 0.079 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 GSG1-like protein UCH PF00443.24 KFO99719.1 - 5.4e-73 245.4 0.0 1e-72 244.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFO99719.1 - 1.4e-36 124.8 0.1 4.7e-36 123.1 0.0 2.0 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 KFO99719.1 - 2.3e-18 66.6 0.7 7.7e-10 38.6 0.3 3.3 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_5 PF13202.1 KFO99719.1 - 5.5e-09 34.9 2.5 0.00014 21.0 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 KFO99719.1 - 1.1e-08 33.7 1.2 0.00078 18.5 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFO99719.1 - 2.1e-08 33.3 1.1 0.029 14.2 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KFO99719.1 - 1.8e-07 31.1 5.6 4.9e-05 23.3 0.6 3.1 2 1 0 3 3 3 2 EF-hand domain pair Ubiquitin_3 PF14836.1 KFO99719.1 - 4.1e-06 26.3 0.1 9.8e-06 25.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.1 KFO99719.1 - 6.2e-05 23.1 3.2 0.001 19.2 0.2 3.0 3 0 0 3 3 3 1 Ubiquitin-like domain EF-hand_8 PF13833.1 KFO99719.1 - 0.00011 21.7 4.1 0.23 11.1 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair PP2C PF00481.16 KFO99720.1 - 1.5e-59 201.4 0.0 2.1e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFO99720.1 - 0.0012 18.2 0.0 0.046 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Pneumo_att_G PF05539.6 KFO99720.1 - 3.6 6.8 9.3 5.4 6.2 6.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G BCAS3 PF12490.3 KFO99721.1 - 3.7e-31 108.3 0.0 9e-31 107.0 0.0 1.5 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.27 KFO99721.1 - 9.3e-06 25.3 0.5 0.00096 18.9 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat T-box PF00907.17 KFO99722.1 - 5.4e-39 133.5 2.0 6.2e-36 123.6 0.1 2.2 1 1 1 2 2 2 2 T-box T-box PF00907.17 KFO99723.1 - 2.6e-72 242.2 0.3 2.9e-72 242.0 0.2 1.0 1 0 0 1 1 1 1 T-box Helicase_C_2 PF13307.1 KFO99724.1 - 1.5e-53 181.1 0.0 3.3e-53 180.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KFO99724.1 - 2.9e-47 160.2 0.0 2.9e-47 160.2 0.0 2.5 3 0 0 3 3 3 1 DEAD_2 DEAD PF00270.24 KFO99724.1 - 1e-05 25.1 0.0 4.3e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFO99724.1 - 0.0039 17.0 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit INTS2 PF14750.1 KFO99725.1 - 0 1559.8 22.3 0 1559.6 15.5 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 Med13_N PF11597.3 KFO99726.1 - 9.6e-132 439.4 5.8 1.4e-131 438.9 0.7 2.7 2 0 0 2 2 2 2 Mediator complex subunit 13 N-terminal Med13_C PF06333.7 KFO99726.1 - 7.3e-129 430.0 0.0 7.3e-129 430.0 0.0 2.9 3 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal zf-RING_2 PF13639.1 KFO99727.1 - 1.9e-11 43.5 9.7 5e-11 42.2 6.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFO99727.1 - 1.4e-10 40.6 6.9 2.4e-10 39.8 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO99727.1 - 7.9e-10 38.6 11.5 1.7e-09 37.5 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFO99727.1 - 2.2e-08 33.6 9.1 5e-08 32.5 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFO99727.1 - 7.8e-08 31.8 11.7 1.7e-07 30.7 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFO99727.1 - 1.9e-06 27.8 10.8 5.8e-06 26.3 7.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFO99727.1 - 7e-06 25.6 5.9 8.7e-06 25.3 3.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFO99727.1 - 2.8e-05 23.8 11.5 6e-05 22.8 8.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFO99727.1 - 0.00013 21.7 3.2 0.00031 20.4 2.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFO99727.1 - 0.014 15.1 7.4 0.43 10.4 5.1 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KFO99727.1 - 0.014 14.8 6.1 0.026 14.0 4.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GAGA PF09237.6 KFO99727.1 - 0.14 11.7 1.6 6.8 6.3 0.0 2.5 2 0 0 2 2 2 0 GAGA factor UPF0547 PF10571.4 KFO99727.1 - 0.64 9.7 0.1 0.64 9.7 0.0 3.1 3 0 0 3 3 2 0 Uncharacterised protein family UPF0547 zf-Nse PF11789.3 KFO99727.1 - 0.88 9.1 8.1 1.6 8.2 5.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KFO99727.1 - 2.7 7.5 9.0 7.1 6.1 5.7 2.1 1 1 1 2 2 2 0 P-11 zinc finger Macoilin PF09726.4 KFO99727.1 - 2.8 6.1 7.1 3.8 5.6 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DZR PF12773.2 KFO99727.1 - 6.1 6.7 7.9 23 4.8 5.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.20 KFO99728.1 - 9.5e-72 241.2 0.0 1.4e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99728.1 - 7.5e-37 126.7 0.0 9.8e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFO99728.1 - 9.2e-09 35.6 2.9 2.2e-08 34.4 2.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFO99728.1 - 5.1e-08 32.2 0.0 1.2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FliT PF05400.8 KFO99728.1 - 0.068 13.5 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Kdo PF06293.9 KFO99728.1 - 0.076 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO99728.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Tubulin PF00091.20 KFO99729.1 - 4.4e-62 209.7 0.1 5.9e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain PTH2 PF01981.11 KFO99730.1 - 5.7e-40 135.6 0.0 7.1e-40 135.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DAO PF01266.19 KFO99730.1 - 0.031 13.1 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Clathrin PF00637.15 KFO99731.1 - 5.5e-211 690.6 40.2 2.3e-33 114.7 1.0 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KFO99731.1 - 6e-47 154.7 2.0 3.7e-06 26.8 0.0 7.7 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KFO99731.1 - 3.3e-33 113.3 0.4 1.5e-32 111.2 0.3 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 KFO99731.1 - 1.1e-14 53.1 0.7 3.4e-14 51.4 0.5 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 KFO99731.1 - 4.8e-08 32.2 4.9 1.4e-05 24.1 0.2 4.3 4 0 0 4 4 4 1 Coatomer WD associated region TPR_7 PF13176.1 KFO99731.1 - 1.2e-05 24.6 11.8 0.57 10.1 0.1 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFO99731.1 - 4.9e-05 23.5 16.9 9.3 7.2 0.0 10.0 10 2 2 12 12 12 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFO99731.1 - 0.00078 18.9 7.2 0.19 11.4 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFO99731.1 - 0.0045 16.8 8.8 3.9 7.6 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO99731.1 - 0.0064 16.8 10.5 5.9 7.3 0.1 6.5 6 2 1 7 7 7 1 Tetratricopeptide repeat OB_NTP_bind PF07717.11 KFO99732.1 - 1.1e-18 67.1 0.0 2.2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFO99732.1 - 4.1e-16 58.8 0.0 1.1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFO99732.1 - 2.2e-13 49.8 0.0 4.5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFO99732.1 - 0.002 17.6 0.0 0.006 16.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Yippee-Mis18 PF03226.9 KFO99733.1 - 5.4e-15 55.2 0.0 7.8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.7 KFO99733.1 - 0.014 15.5 5.6 0.067 13.3 3.9 1.9 1 1 0 1 1 1 0 CHY zinc finger Evr1_Alr PF04777.8 KFO99733.1 - 0.046 13.6 0.6 0.65 9.9 0.1 2.1 2 0 0 2 2 2 0 Erv1 / Alr family NinE PF05322.6 KFO99733.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 NINE Protein GDPD PF03009.12 KFO99734.1 - 5.2e-31 108.0 0.1 2e-23 83.1 0.0 2.0 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KFO99734.1 - 9.4e-06 25.6 0.1 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2146 PF10220.4 KFO99735.1 - 3.1e-301 1001.6 0.0 3.5e-301 1001.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2146) zf-B_box PF00643.19 KFO99737.1 - 8.8e-10 38.3 8.9 8.8e-10 38.3 6.2 2.9 3 0 0 3 3 3 1 B-box zinc finger MATH PF00917.21 KFO99737.1 - 1.7e-07 31.4 0.0 5.5e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 MATH domain zf-C3HC4_2 PF13923.1 KFO99737.1 - 4.4e-05 23.4 18.0 4.4e-05 23.4 12.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO99737.1 - 0.00061 19.4 14.8 0.00061 19.4 10.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF148 PF02520.12 KFO99737.1 - 0.017 14.8 4.8 0.38 10.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.7 KFO99737.1 - 0.046 13.5 4.9 0.91 9.3 1.4 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 KFO99737.1 - 0.082 11.3 1.3 0.16 10.4 0.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.20 KFO99737.1 - 0.94 9.6 14.9 1.4 9.1 3.0 3.6 3 0 0 3 3 3 0 Syntaxin MitMem_reg PF13012.1 KFO99737.1 - 8.8 6.4 12.4 3.8 7.6 1.6 3.8 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function PP2C PF00481.16 KFO99738.1 - 9.4e-65 218.5 0.2 1.3e-64 218.0 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFO99738.1 - 0.00025 20.5 0.1 0.00079 18.8 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFO99738.1 - 0.0057 16.3 0.8 0.63 9.7 0.1 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Mito_fiss_reg PF05308.6 KFO99738.1 - 0.58 9.4 4.5 1.4 8.1 3.1 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KFO99738.1 - 5.4 6.2 5.4 8.9 5.4 3.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Rad51 PF08423.6 KFO99739.1 - 3e-33 114.8 0.1 6e-31 107.2 0.1 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFO99739.1 - 2.6e-09 36.7 0.1 5.8e-09 35.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KFO99739.1 - 5.3e-05 22.4 0.2 0.0001 21.5 0.1 1.5 2 0 0 2 2 2 1 KaiC RecA PF00154.16 KFO99739.1 - 0.00046 19.3 0.2 0.0046 16.0 0.1 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_17 PF13207.1 KFO99739.1 - 0.00079 20.2 0.1 0.24 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFO99739.1 - 0.0066 16.5 0.4 0.063 13.4 0.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KFO99739.1 - 0.024 14.9 0.1 0.095 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 KFO99739.1 - 0.033 13.0 0.0 0.058 12.2 0.0 1.4 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain cobW PF02492.14 KFO99739.1 - 0.091 12.2 0.5 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFO99739.1 - 0.11 12.3 0.1 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFO99739.1 - 0.11 12.0 0.1 0.37 10.4 0.1 2.0 1 1 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 KFO99739.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain 7tm_1 PF00001.16 KFO99740.1 - 1.2e-50 172.0 12.7 1.5e-50 171.7 8.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFO99740.1 - 4.5e-07 29.2 10.1 6.5e-07 28.7 7.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFO99740.1 - 3.5e-05 23.0 5.0 3.5e-05 23.0 3.5 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 KFO99740.1 - 6.4e-05 22.2 13.0 0.00076 18.7 9.0 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cytochrom_B_N_2 PF13631.1 KFO99740.1 - 0.0087 15.8 1.2 0.02 14.7 0.6 1.8 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB 7TM_GPCR_Srh PF10318.4 KFO99740.1 - 0.032 13.0 9.4 0.064 12.0 6.5 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh FAM101 PF15068.1 KFO99741.1 - 1.3e-69 233.7 2.4 1.4e-69 233.6 1.6 1.0 1 0 0 1 1 1 1 FAM101 family Levi_coat PF01819.12 KFO99741.1 - 0.069 12.7 0.2 0.16 11.5 0.0 1.6 1 1 1 2 2 2 0 Levivirus coat protein Vps53_N PF04100.7 KFO99742.1 - 8.5e-171 567.9 0.7 1.4e-170 567.2 0.5 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 KFO99742.1 - 2.1e-07 30.1 1.2 2.1e-07 30.1 0.8 2.0 2 1 1 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 KFO99742.1 - 0.00034 19.3 4.5 0.00065 18.4 3.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4413 PF14372.1 KFO99742.1 - 0.0046 16.9 0.5 0.046 13.6 0.0 3.0 3 1 1 4 4 3 1 Domain of unknown function (DUF4413) Laminin_II PF06009.7 KFO99742.1 - 0.0094 15.7 5.9 0.015 15.0 2.9 2.1 2 0 0 2 2 2 1 Laminin Domain II AAA_13 PF13166.1 KFO99742.1 - 0.015 13.8 6.1 0.016 13.6 3.6 1.5 1 1 0 1 1 1 0 AAA domain TBPIP PF07106.8 KFO99742.1 - 0.018 14.6 3.2 0.042 13.3 2.2 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 KFO99742.1 - 0.018 14.8 3.4 0.022 14.5 1.1 2.0 2 0 0 2 2 2 0 Tropomyosin like Nairo_nucleo PF02477.10 KFO99742.1 - 0.027 13.2 0.6 0.046 12.4 0.4 1.3 1 0 0 1 1 1 0 Nucleocapsid N protein MCPsignal PF00015.16 KFO99742.1 - 0.069 12.6 2.7 0.073 12.5 0.4 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GrpE PF01025.14 KFO99742.1 - 0.075 12.5 2.0 0.22 11.0 1.4 1.9 1 0 0 1 1 1 0 GrpE IncA PF04156.9 KFO99742.1 - 0.079 12.5 4.1 0.088 12.3 1.4 2.2 2 0 0 2 2 1 0 IncA protein ING PF12998.2 KFO99742.1 - 0.098 12.9 8.9 0.051 13.8 3.0 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Vps51 PF08700.6 KFO99742.1 - 0.18 11.6 7.9 0.12 12.2 1.2 3.5 3 1 0 3 3 2 0 Vps51/Vps67 COG5 PF10392.4 KFO99742.1 - 0.19 11.6 2.9 0.19 11.6 0.6 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Tropomyosin PF00261.15 KFO99742.1 - 0.29 10.2 7.3 0.022 13.8 1.0 2.1 3 0 0 3 3 3 0 Tropomyosin DUF1664 PF07889.7 KFO99742.1 - 0.29 10.9 9.5 0.63 9.8 2.3 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) FUSC PF04632.7 KFO99742.1 - 0.37 9.1 0.2 0.54 8.6 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 KFO99742.1 - 0.39 9.8 2.5 3.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Snf7 PF03357.16 KFO99742.1 - 0.47 9.8 10.8 0.17 11.2 4.3 2.5 2 0 0 2 2 2 0 Snf7 DUF948 PF06103.6 KFO99742.1 - 1.2 9.0 5.1 1.9 8.4 0.9 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 KFO99742.1 - 1.9 8.5 10.2 0.17 11.8 2.1 2.8 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin_2 PF14523.1 KFO99742.1 - 2.9 7.9 8.1 3.5 7.7 3.1 3.1 2 1 1 3 3 3 0 Syntaxin-like protein COG2 PF06148.6 KFO99742.1 - 5.6 6.8 10.1 0.62 9.9 2.1 3.0 3 1 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TRAM_LAG1_CLN8 PF03798.11 KFO99743.1 - 9.4e-46 155.8 15.8 1.1e-45 155.6 10.9 1.0 1 0 0 1 1 1 1 TLC domain Glyoxalase_2 PF12681.2 KFO99745.1 - 0.0036 17.9 0.0 0.011 16.3 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFO99745.1 - 0.007 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SpoU_methylase PF00588.14 KFO99746.1 - 1.1e-24 86.9 0.0 2.6e-22 79.2 0.0 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KFO99746.1 - 3.2e-05 24.0 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Thioredoxin_8 PF13905.1 KFO99747.1 - 1.8e-22 79.2 0.0 4.1e-18 65.2 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFO99747.1 - 8.2e-12 45.3 0.0 2e-09 37.6 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 KFO99747.1 - 2.1e-08 34.2 0.0 1.4e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.15 KFO99747.1 - 2e-07 30.6 0.2 0.00013 21.5 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin Thioredoxin_7 PF13899.1 KFO99747.1 - 1.4e-06 28.2 0.0 1.7e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 KFO99747.1 - 1.8e-06 27.5 0.0 3.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFO99747.1 - 4e-06 26.5 0.0 1.7e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.19 KFO99747.1 - 0.0034 17.3 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin NADH_4Fe-4S PF10589.4 KFO99747.1 - 0.011 14.8 0.3 0.044 12.9 0.0 2.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF953 PF06110.6 KFO99747.1 - 0.12 11.7 0.1 1.7 8.0 0.1 2.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) MatE PF01554.13 KFO99748.1 - 5e-55 185.5 26.4 7.7e-29 100.3 6.7 2.4 2 0 0 2 2 2 2 MatE Dispanin PF04505.7 KFO99748.1 - 0.47 10.0 5.6 0.72 9.4 0.9 2.9 2 0 0 2 2 2 0 Interferon-induced transmembrane protein MatE PF01554.13 KFO99749.1 - 5.7e-55 185.3 36.2 3e-31 108.2 6.8 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KFO99749.1 - 0.00017 21.4 13.0 0.00017 21.4 9.0 4.4 1 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 KFO99749.1 - 0.0014 18.1 0.6 0.0014 18.1 0.4 3.7 3 0 0 3 3 3 1 Interferon-induced transmembrane protein Aldedh PF00171.17 KFO99750.1 - 1.1e-86 290.9 0.0 1.3e-86 290.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1196 PF06709.6 KFO99750.1 - 0.0054 16.6 0.1 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1196) Aldedh PF00171.17 KFO99751.1 - 4.3e-90 302.2 0.0 5e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 KFO99752.1 - 3.1e-70 236.2 0.0 4.6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 KFO99752.1 - 1.2e-52 178.4 5.6 1.9e-52 177.8 3.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 KFO99752.1 - 6.2e-49 166.4 0.0 1.1e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFO99752.1 - 1.4e-06 27.5 0.2 3.9e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFO99752.1 - 7.1e-06 25.5 0.1 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFO99752.1 - 0.0018 17.3 0.0 0.0068 15.4 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFO99752.1 - 0.0087 15.8 0.0 0.036 13.7 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family GATA PF00320.22 KFO99753.1 - 9.1e-32 108.1 16.3 2.9e-16 58.5 3.5 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFO99753.1 - 3.8e-06 26.1 6.2 0.013 14.8 0.7 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 KFO99753.1 - 0.0005 19.8 0.6 0.11 12.2 0.1 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 KFO99753.1 - 0.0054 16.6 3.9 0.22 11.4 0.2 3.4 4 0 0 4 4 3 1 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 KFO99753.1 - 0.015 14.9 3.4 2.3 7.8 0.5 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.2 KFO99753.1 - 0.015 15.1 6.9 1.7 8.5 5.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon BaffR-Tall_bind PF09256.5 KFO99753.1 - 0.032 13.8 3.1 1.2 8.8 0.0 3.4 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding OrfB_Zn_ribbon PF07282.6 KFO99753.1 - 0.038 13.6 5.7 0.6 9.8 0.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 KFO99753.1 - 0.063 13.0 1.0 0.063 13.0 0.7 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.5 KFO99753.1 - 0.1 12.5 4.8 8.9 6.3 0.1 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) C1_3 PF07649.7 KFO99753.1 - 0.11 12.5 1.0 17 5.5 0.1 2.7 2 0 0 2 2 2 0 C1-like domain TFIIA PF03153.8 KFO99753.1 - 0.2 11.5 1.8 0.23 11.3 1.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cytochrome_C7 PF14522.1 KFO99753.1 - 0.28 10.8 7.4 0.15 11.6 2.4 2.2 1 1 1 2 2 2 0 Cytochrome c7 Cytochrome_C554 PF13435.1 KFO99753.1 - 0.55 10.2 4.0 0.98 9.4 2.3 1.9 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 KFO99753.1 - 1.1 9.5 6.0 0.41 11.0 0.5 2.3 1 1 1 2 2 2 0 Cytochrome c3 Elf1 PF05129.8 KFO99753.1 - 2 8.1 8.4 3 7.5 0.0 2.7 2 1 1 3 3 2 0 Transcription elongation factor Elf1 like Prim_Zn_Ribbon PF08273.7 KFO99753.1 - 2 8.5 15.8 0.18 11.8 2.2 3.3 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-ribbon_3 PF13248.1 KFO99753.1 - 5.8 6.2 12.5 5.9 6.2 1.7 3.3 3 1 0 3 3 3 0 zinc-ribbon domain Prok-RING_2 PF14445.1 KFO99753.1 - 8.3 6.4 6.9 1.5 8.8 0.4 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 H2TH PF06831.9 KFO99754.1 - 5.7e-14 51.6 0.0 9.7e-14 50.8 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 KFO99754.1 - 3.6e-09 36.9 0.0 6.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain SQS_PSY PF00494.14 KFO99755.1 - 3.8e-43 147.6 0.0 6.2e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase HAUS4 PF14735.1 KFO99755.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Peptidase_C1 PF00112.18 KFO99756.1 - 5.1e-67 225.9 2.2 6e-67 225.7 1.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 KFO99756.1 - 2.7e-18 65.2 0.2 5.8e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.10 KFO99756.1 - 0.092 11.2 1.5 2.4 6.6 0.2 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Defensin_beta PF00711.14 KFO99757.1 - 1.5e-09 37.5 11.6 1.8e-09 37.3 8.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_big PF14862.1 KFO99757.1 - 1.7e-07 31.2 0.8 1.7e-07 31.2 0.5 1.1 1 0 0 1 1 1 1 Big defensin Gamma-thionin PF00304.15 KFO99757.1 - 0.055 13.4 10.0 0.069 13.1 6.9 1.1 1 0 0 1 1 1 0 Gamma-thionin family Defensin_beta_2 PF13841.1 KFO99757.1 - 0.63 10.4 11.3 1 9.7 7.8 1.4 1 1 0 1 1 1 0 Beta defensin Defensin_beta PF00711.14 KFO99758.1 - 4.1e-05 23.3 6.2 5e-05 23.1 4.3 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta_2 PF13841.1 KFO99758.1 - 0.00016 21.9 6.4 0.0002 21.6 4.4 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.14 KFO99759.1 - 1.8e-09 37.3 8.6 2.1e-09 37.1 6.0 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.13 KFO99759.1 - 0.095 12.6 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Defensin propeptide Defensin_beta PF00711.14 KFO99760.1 - 1.6e-11 43.9 6.1 1.7e-11 43.8 4.2 1.0 1 0 0 1 1 1 1 Beta defensin Defensin_big PF14862.1 KFO99760.1 - 0.28 11.2 2.1 0.31 11.1 1.4 1.2 1 0 0 1 1 1 0 Big defensin Defensin_beta PF00711.14 KFO99761.1 - 8.6e-09 35.1 10.6 1e-08 34.9 7.4 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_beta PF00711.14 KFO99762.1 - 5.3e-07 29.4 11.5 6.4e-07 29.1 7.9 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.13 KFO99762.1 - 0.021 14.7 0.1 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Defensin propeptide NDK PF00334.14 KFO99763.1 - 3e-37 127.4 0.0 3.3e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 KFO99763.1 - 0.022 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Metallophos PF00149.23 KFO99764.1 - 5.1e-27 94.5 0.6 6e-27 94.3 0.4 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_8 PF13855.1 KFO99765.1 - 1.1e-27 95.5 14.1 7.6e-11 41.6 0.7 3.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFO99765.1 - 8.8e-19 66.7 13.2 1.2e-05 24.7 1.1 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.11 KFO99765.1 - 3.4e-15 55.6 0.0 5.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.1 KFO99765.1 - 1.4e-13 50.6 0.8 6.1e-07 29.2 0.0 2.3 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFO99765.1 - 3.1e-12 44.7 16.2 0.11 12.6 0.3 7.7 8 0 0 8 8 8 5 Leucine Rich Repeat Ig_2 PF13895.1 KFO99765.1 - 6e-10 39.1 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO99765.1 - 1.2e-07 32.1 0.1 4.5e-07 30.2 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 KFO99765.1 - 2.9e-06 27.3 0.0 7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.20 KFO99765.1 - 7.6e-05 22.7 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 KFO99765.1 - 0.0034 16.9 3.0 0.071 12.6 1.0 2.4 1 1 1 2 2 2 1 Leucine-rich repeat LRR_7 PF13504.1 KFO99765.1 - 0.011 15.7 17.2 8.9 7.0 0.4 7.1 7 0 0 7 7 7 0 Leucine rich repeat V-set PF07686.12 KFO99765.1 - 0.068 13.0 0.0 0.29 11.0 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain LRR_6 PF13516.1 KFO99765.1 - 0.59 10.3 21.8 1.2 9.4 0.3 5.9 7 0 0 7 7 7 0 Leucine Rich repeat LRR_3 PF07725.7 KFO99765.1 - 8.1 6.4 7.7 29 4.6 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat Acyl-CoA_dh_1 PF00441.19 KFO99766.1 - 6e-37 127.0 1.8 8.5e-37 126.5 1.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 KFO99766.1 - 2.3e-20 73.1 2.5 3.2e-20 72.7 1.7 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFO99766.1 - 1.8e-19 68.9 0.0 3.9e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain 7tm_1 PF00001.16 KFO99768.1 - 1.5e-07 30.8 0.7 1.9e-07 30.4 0.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) I-set PF07679.11 KFO99769.1 - 4.5e-108 353.3 0.0 1.1e-15 57.1 0.0 11.6 12 0 0 12 12 12 9 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99769.1 - 9.8e-84 275.5 7.4 3.4e-11 43.1 0.0 11.5 11 0 0 11 11 11 10 Immunoglobulin domain fn3 PF00041.16 KFO99769.1 - 9.5e-81 266.0 10.6 9.2e-14 51.3 0.0 7.1 6 0 0 6 6 6 6 Fibronectin type III domain Ig_3 PF13927.1 KFO99769.1 - 3.6e-68 225.9 19.4 4.8e-10 39.7 0.1 11.7 11 0 0 11 11 11 10 Immunoglobulin domain ig PF00047.20 KFO99769.1 - 4.5e-51 170.8 2.1 1.5e-08 34.6 0.0 11.7 10 0 0 10 10 10 7 Immunoglobulin domain V-set PF07686.12 KFO99769.1 - 1.6e-36 124.6 9.8 1.9e-05 24.5 0.0 12.3 9 3 1 10 10 10 7 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO99769.1 - 6.5e-16 58.0 2.5 0.15 12.0 0.0 8.9 9 1 1 10 10 9 4 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFO99769.1 - 6.8e-09 35.6 0.0 0.059 13.3 0.0 7.0 6 0 0 6 6 6 1 Immunoglobulin C1-set domain V-set_CD47 PF08204.6 KFO99769.1 - 8.2e-07 28.8 0.1 0.0097 15.6 0.0 4.9 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Receptor_2B4 PF11465.3 KFO99769.1 - 2.7e-06 27.2 2.2 0.37 10.7 0.0 5.7 7 0 0 7 7 7 2 Natural killer cell receptor 2B4 Interfer-bind PF09294.5 KFO99769.1 - 1.1e-05 25.3 0.1 0.43 10.6 0.0 4.2 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III BiPBP_C PF06832.7 KFO99769.1 - 0.027 14.4 0.0 0.61 10.0 0.0 3.0 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family ATP1G1_PLM_MAT8 PF02038.11 KFO99770.1 - 2.4e-29 100.1 0.0 2.8e-29 99.8 0.0 1.1 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family OAD_gamma PF04277.8 KFO99770.1 - 0.016 15.5 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain IncA PF04156.9 KFO99770.1 - 0.029 13.9 0.1 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 IncA protein Glycophorin_A PF01102.13 KFO99770.1 - 0.032 13.9 0.1 0.051 13.3 0.0 1.4 1 1 0 1 1 1 0 Glycophorin A OSTbeta PF15048.1 KFO99770.1 - 0.055 13.5 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2367 PF10164.4 KFO99770.1 - 0.16 11.8 0.3 0.23 11.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Trypsin PF00089.21 KFO99771.1 - 4.6e-41 140.8 0.5 5e-41 140.6 0.4 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.10 KFO99771.1 - 0.025 13.9 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Tissue_fac PF01108.12 KFO99772.1 - 2e-26 91.7 0.7 8.1e-26 89.8 0.0 2.5 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.5 KFO99772.1 - 1.5e-08 34.6 1.4 1.7e-08 34.4 0.1 1.7 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFO99772.1 - 0.00018 21.5 4.1 0.041 14.0 0.2 2.8 2 1 0 2 2 2 2 Fibronectin type III domain Trypsin PF00089.21 KFO99773.1 - 1.3e-69 234.1 0.1 1.6e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 KFO99773.1 - 1.2e-18 67.1 0.5 2.2e-18 66.2 0.3 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.1 KFO99773.1 - 1.4e-06 28.2 0.0 2.9e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 KFO99773.1 - 3.3e-06 26.6 0.0 5.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) SRCR PF00530.13 KFO99773.1 - 0.00011 22.5 0.2 0.0003 21.0 0.2 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.5 KFO99773.1 - 0.0091 16.2 0.9 0.036 14.2 0.7 1.9 1 1 0 1 1 1 1 Hepsin, SRCR YecR PF13992.1 KFO99773.1 - 0.053 13.6 0.1 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 YecR-like lipoprotein Ig_2 PF13895.1 KFO99774.1 - 1.3e-07 31.6 0.1 2.3e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFO99774.1 - 1.7e-07 31.0 0.1 3.1e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFO99774.1 - 2.2e-06 27.4 0.1 1.4e-05 24.8 0.0 2.3 1 1 1 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 KFO99774.1 - 0.00038 20.5 0.8 0.002 18.1 0.6 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFO99774.1 - 0.0031 18.0 0.9 0.012 16.1 0.7 2.1 1 1 0 1 1 1 1 Immunoglobulin domain Tmemb_9 PF05434.6 KFO99774.1 - 0.037 13.7 0.1 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 TMEM9 Glycophorin_A PF01102.13 KFO99774.1 - 0.5 10.1 4.5 0.91 9.3 2.9 1.6 1 1 0 1 1 1 0 Glycophorin A V-set PF07686.12 KFO99775.1 - 7.4e-19 67.7 0.3 1.1e-18 67.1 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFO99775.1 - 8e-07 28.8 0.0 2.6e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99775.1 - 4.6e-06 26.6 0.3 7.1e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 Immunoglobulin domain DUF1191 PF06697.7 KFO99775.1 - 4e-05 22.5 0.0 5.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) PALP PF00291.20 KFO99775.1 - 7.1e-05 22.1 0.0 9.8e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ig PF00047.20 KFO99775.1 - 8.4e-05 22.6 4.3 0.0011 19.0 3.0 2.3 1 1 0 1 1 1 1 Immunoglobulin domain Syndecan PF01034.15 KFO99775.1 - 0.0013 18.3 0.1 0.0066 16.0 0.0 2.2 3 0 0 3 3 3 1 Syndecan domain EphA2_TM PF14575.1 KFO99775.1 - 0.0019 18.5 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KFO99775.1 - 0.0023 17.4 0.4 0.0044 16.5 0.3 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 KFO99775.1 - 0.0044 15.3 0.7 0.17 10.0 0.2 2.2 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 KFO99775.1 - 0.0083 15.7 0.1 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protocadherin Ig_3 PF13927.1 KFO99775.1 - 0.015 15.7 4.1 0.052 14.0 2.8 2.0 1 1 0 1 1 1 0 Immunoglobulin domain Vpu PF00558.14 KFO99775.1 - 0.036 13.6 0.0 0.095 12.2 0.0 1.6 2 0 0 2 2 2 0 Vpu protein Mid2 PF04478.7 KFO99775.1 - 0.042 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Shisa PF13908.1 KFO99775.1 - 0.051 13.7 0.0 0.051 13.7 0.0 1.5 2 0 0 2 2 1 0 Wnt and FGF inhibitory regulator WBP-1 PF11669.3 KFO99775.1 - 0.056 13.5 0.0 0.32 11.1 0.0 2.1 2 1 1 3 3 3 0 WW domain-binding protein 1 SKG6 PF08693.5 KFO99775.1 - 0.066 12.5 1.6 0.12 11.6 1.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAM176 PF14851.1 KFO99775.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 FAM176 family TMEM154 PF15102.1 KFO99775.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family V-set PF07686.12 KFO99776.1 - 4.1e-10 39.5 0.0 8.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gE PF02480.11 KFO99776.1 - 0.00027 19.3 0.1 0.23 9.7 0.0 2.0 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E ig PF00047.20 KFO99776.1 - 0.009 16.1 0.1 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin domain DUF4381 PF14316.1 KFO99776.1 - 0.023 14.7 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) V-set PF07686.12 KFO99778.1 - 3.5e-13 49.4 0.0 5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFO99778.1 - 0.0052 17.2 0.2 0.22 12.0 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin domain CitMHS PF03600.11 KFO99778.1 - 0.072 11.6 0.0 0.087 11.3 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter V-set PF07686.12 KFO99779.1 - 3.6e-20 71.9 0.0 5.4e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFO99779.1 - 3.9e-06 26.6 0.0 8e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99779.1 - 7.9e-06 25.9 0.0 1.7e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFO99779.1 - 4e-05 23.6 0.5 0.00042 20.3 0.3 2.3 1 1 0 1 1 1 1 Immunoglobulin domain DUF3481 PF11980.3 KFO99779.1 - 0.00076 19.2 0.2 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) Ig_3 PF13927.1 KFO99779.1 - 0.0047 17.4 2.4 0.088 13.3 1.7 2.2 1 1 0 1 1 1 1 Immunoglobulin domain EphA2_TM PF14575.1 KFO99779.1 - 0.0054 17.1 0.6 0.0092 16.3 0.4 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KFO99779.1 - 0.0084 15.8 0.2 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 KFO99779.1 - 0.031 12.5 1.2 1.1 7.3 1.3 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 KFO99779.1 - 0.031 13.9 0.4 0.043 13.4 0.3 1.1 1 0 0 1 1 1 0 Rifin/stevor family Protocadherin PF08374.6 KFO99779.1 - 0.044 13.4 1.9 0.068 12.7 1.0 1.4 2 0 0 2 2 2 0 Protocadherin DUF3169 PF11368.3 KFO99779.1 - 0.056 12.6 0.1 0.082 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Rax2 PF12768.2 KFO99779.1 - 0.15 11.2 0.1 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Shisa PF13908.1 KFO99779.1 - 0.18 11.9 0.5 0.25 11.4 0.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ITAM PF02189.10 KFO99780.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif IL12p40_C PF10420.4 KFO99780.1 - 0.094 12.8 1.2 0.23 11.6 0.5 1.7 1 1 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus Ig_2 PF13895.1 KFO99781.1 - 0.00024 21.1 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ITAM PF02189.10 KFO99781.1 - 0.00068 19.7 0.6 0.0014 18.7 0.4 1.5 1 0 0 1 1 1 1 Immunoreceptor tyrosine-based activation motif DAP10 PF07213.6 KFO99781.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 DAP10 membrane protein Zw10 PF06248.8 KFO99782.1 - 2.6e-228 759.0 14.4 3.2e-228 758.7 10.0 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Flagellin_C PF00700.16 KFO99782.1 - 0.012 15.7 1.4 0.043 13.9 0.2 2.5 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region 7tm_1 PF00001.16 KFO99783.1 - 6.4e-87 290.9 9.0 9.6e-87 290.3 6.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFO99783.1 - 2e-11 43.5 19.1 7.4e-07 28.5 7.4 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Rifin_STEVOR PF02009.11 KFO99783.1 - 0.0059 16.2 0.4 0.014 15.0 0.3 1.6 1 0 0 1 1 1 1 Rifin/stevor family 7TM_GPCR_Srv PF10323.4 KFO99783.1 - 0.015 14.4 20.9 0.15 11.1 0.5 3.0 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv TMEM154 PF15102.1 KFO99783.1 - 0.037 13.7 1.9 0.19 11.4 0.3 2.7 3 1 0 3 3 3 0 TMEM154 protein family PemK PF02452.12 KFO99783.1 - 0.095 12.9 0.1 0.25 11.5 0.1 1.8 1 1 0 1 1 1 0 PemK-like protein DUF912 PF06024.7 KFO99783.1 - 1.9 8.5 9.3 3.5 7.7 0.5 3.8 4 1 1 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TPR_11 PF13414.1 KFO99784.1 - 2e-19 69.0 7.7 4.8e-15 54.9 2.6 2.9 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFO99784.1 - 5.4e-13 47.7 8.5 1.8e-05 24.2 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFO99784.1 - 2.6e-11 42.6 11.3 2e-05 23.9 1.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFO99784.1 - 2.8e-07 29.8 4.6 0.0098 15.6 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFO99784.1 - 1.1e-06 28.4 8.0 1.9e-06 27.6 1.5 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_EZ PF13513.1 KFO99784.1 - 2.8e-05 24.4 3.5 11 6.6 0.0 5.9 5 0 0 5 5 5 0 HEAT-like repeat TPR_16 PF13432.1 KFO99784.1 - 5.1e-05 23.8 0.0 0.00041 20.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT_2 PF13646.1 KFO99784.1 - 7.9e-05 22.8 6.1 0.011 15.9 0.1 4.9 4 2 1 5 5 5 2 HEAT repeats TPR_19 PF14559.1 KFO99784.1 - 0.00022 21.5 2.3 0.14 12.5 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO99784.1 - 0.00028 21.2 0.0 0.16 12.6 0.0 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat HEAT PF02985.17 KFO99784.1 - 0.00036 20.3 0.5 7.9 6.8 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat Apc3 PF12895.2 KFO99784.1 - 0.0005 20.1 9.4 0.003 17.6 6.5 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Arm PF00514.18 KFO99784.1 - 0.001 18.7 9.9 10 6.1 0.1 6.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TPR_7 PF13176.1 KFO99784.1 - 0.0043 16.7 4.1 0.23 11.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO99784.1 - 0.01 16.2 1.2 0.14 12.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFO99784.1 - 0.011 15.6 0.1 0.049 13.4 0.0 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFO99784.1 - 0.013 15.3 8.0 0.11 12.4 0.1 3.6 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 KFO99784.1 - 0.022 14.9 3.9 0.17 12.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KFO99784.1 - 0.31 10.9 5.4 2.5 8.0 0.2 3.8 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain I-set PF07679.11 KFO99785.1 - 8e-78 256.3 5.7 6.3e-19 67.6 0.1 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99785.1 - 7e-51 170.2 0.7 5.5e-11 42.4 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFO99785.1 - 4.2e-38 129.6 7.4 2e-07 31.3 0.1 5.9 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFO99785.1 - 7.1e-36 122.1 2.8 3.4e-07 30.2 0.1 6.2 6 0 0 6 6 6 5 Immunoglobulin domain fn3 PF00041.16 KFO99785.1 - 2.9e-26 91.4 0.2 4.4e-14 52.3 0.0 3.1 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.12 KFO99785.1 - 2e-23 82.4 2.8 0.00076 19.3 0.0 6.2 5 0 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO99785.1 - 2e-12 46.8 4.2 0.0032 17.3 0.0 5.4 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFO99785.1 - 1.4e-08 34.5 2.8 0.00079 19.3 0.0 4.8 5 0 0 5 5 5 2 Immunoglobulin C1-set domain PTPS PF01242.14 KFO99787.1 - 7.1e-33 112.9 0.1 8.7e-33 112.6 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase RPE65 PF03055.10 KFO99788.1 - 1.3e-127 426.3 0.0 1.6e-127 426.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PepSY PF03413.14 KFO99788.1 - 0.17 12.5 0.3 13 6.5 0.1 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain IL1 PF00340.14 KFO99789.1 - 7.3e-30 102.9 0.6 1e-29 102.4 0.4 1.1 1 0 0 1 1 1 1 Interleukin-1 / 18 CybS PF05328.7 KFO99790.1 - 2.2e-37 127.6 0.2 2.6e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 CybS ASFV_J13L PF05568.6 KFO99790.1 - 0.012 15.1 0.3 0.016 14.7 0.2 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein CDC27 PF09507.5 KFO99791.1 - 0.89 8.6 52.1 1.2 8.3 36.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PIH1 PF08190.7 KFO99792.1 - 4.4e-42 144.6 0.0 9.6e-42 143.5 0.0 1.5 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 KFO99792.1 - 0.0017 18.8 0.0 0.0039 17.7 0.0 1.6 1 0 0 1 1 1 1 CS domain HSP20 PF00011.16 KFO99792.1 - 0.0023 17.7 0.1 0.0038 17.0 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family 2-oxoacid_dh PF00198.18 KFO99793.1 - 8.6e-82 273.8 0.1 1.1e-81 273.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFO99793.1 - 3.4e-32 109.9 0.6 1.6e-15 56.4 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.12 KFO99793.1 - 5.7e-19 67.4 0.6 1.4e-18 66.2 0.4 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KFO99793.1 - 0.007 16.0 0.0 4.4 7.0 0.0 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_2 PF12700.2 KFO99793.1 - 0.13 11.4 0.1 3.6 6.6 0.0 2.5 2 1 1 3 3 3 0 HlyD family secretion protein HSP20 PF00011.16 KFO99794.1 - 2.6e-19 68.9 0.0 3.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 KFO99794.1 - 3.6e-06 27.0 0.1 9e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Alpha crystallin A chain, N terminal HSP20 PF00011.16 KFO99795.1 - 3.8e-29 100.5 0.2 4.6e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 KFO99795.1 - 6.1e-24 84.0 1.2 1e-23 83.2 0.9 1.4 1 0 0 1 1 1 1 Alpha crystallin A chain, N terminal DUF2431 PF10354.4 KFO99796.1 - 2.5e-42 144.6 0.0 5.2e-42 143.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.9 KFO99796.1 - 4.4e-17 62.0 0.0 1.1e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Methyltransf_26 PF13659.1 KFO99796.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA-synt_2d PF01409.15 KFO99796.1 - 0.0016 17.7 0.0 0.0051 16.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Glyco_transf_22 PF03901.12 KFO99797.1 - 6.7e-119 397.6 32.4 7.8e-119 397.3 22.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Sigma_reg_N PF13800.1 KFO99797.1 - 0.6 10.1 2.9 2.2 8.3 0.2 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Pkinase PF00069.20 KFO99798.1 - 6.3e-70 235.2 0.0 1.2e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99798.1 - 3.4e-36 124.6 0.0 5.8e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO99798.1 - 2e-08 33.5 0.0 4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFO99798.1 - 0.016 14.3 0.1 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTG PF07742.7 KFO99799.1 - 5.1e-45 151.8 0.1 6.9e-45 151.4 0.1 1.2 1 0 0 1 1 1 1 BTG family PD-C2-AF1 PF09310.5 KFO99801.1 - 7.1e-134 444.7 19.3 7.9e-134 444.6 13.4 1.0 1 0 0 1 1 1 1 POU domain, class 2, associating factor 1 zf-C2H2 PF00096.21 KFO99803.1 - 7.2e-16 57.4 78.7 5.2e-05 23.3 3.9 8.6 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO99803.1 - 7.9e-13 48.0 17.6 1.9e-06 27.8 2.3 9.9 12 0 0 12 12 12 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO99803.1 - 3.1e-09 36.5 77.1 0.00039 20.5 2.7 9.0 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO99803.1 - 6.9e-06 26.0 40.8 0.0025 17.9 0.6 6.4 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO99803.1 - 2e-05 24.6 35.8 0.18 12.0 0.0 6.4 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFO99803.1 - 0.00076 19.2 1.4 0.00076 19.2 1.0 6.6 6 0 0 6 6 6 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFO99803.1 - 0.0019 18.2 6.9 0.0019 18.2 4.8 5.2 4 1 1 5 5 5 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFO99803.1 - 0.006 16.7 62.5 0.08 13.2 1.2 8.0 7 1 0 7 7 7 3 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 KFO99803.1 - 0.025 14.2 0.8 0.025 14.2 0.6 5.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KFO99803.1 - 2.8 8.1 40.2 0.47 10.5 4.3 5.8 2 1 5 7 7 7 0 C2H2 type zinc-finger (2 copies) LRR_6 PF13516.1 KFO99804.1 - 1.6e-10 39.8 7.2 0.091 12.8 0.0 7.0 6 0 0 6 6 6 3 Leucine Rich repeat NACHT PF05729.7 KFO99804.1 - 4.6e-08 32.8 0.0 1.5e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain LRR_4 PF12799.2 KFO99804.1 - 0.002 17.7 3.1 0.22 11.2 0.0 4.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) STAS PF01740.16 KFO99804.1 - 0.0079 15.6 0.1 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 STAS domain FdtA PF05523.6 KFO99804.1 - 0.054 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 WxcM-like, C-terminal LRR_7 PF13504.1 KFO99804.1 - 1.4 9.4 7.4 7.3 7.2 0.1 5.2 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 KFO99804.1 - 1.5 8.6 10.8 0.36 10.6 1.0 4.2 3 2 1 4 4 4 0 Leucine rich repeat Lamprin PF06403.6 KFO99805.1 - 0.2 11.4 4.9 0.2 11.3 3.4 1.0 1 0 0 1 1 1 0 Lamprin Lamprin PF06403.6 KFO99806.1 - 0.12 12.1 3.0 0.12 12.1 2.1 1.0 1 0 0 1 1 1 0 Lamprin TNF PF00229.13 KFO99807.1 - 4.2e-30 103.9 1.0 6.7e-30 103.2 0.7 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family RII_binding_1 PF10522.4 KFO99808.1 - 0.16 12.1 2.9 19 5.8 0.0 4.4 4 0 0 4 4 4 0 RII binding domain DAGK_acc PF00609.14 KFO99809.1 - 5.8e-54 182.5 0.0 1.1e-53 181.6 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFO99809.1 - 1.3e-29 102.2 0.0 3.5e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFO99809.1 - 1.6e-19 69.3 25.7 1e-10 41.1 3.9 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFO99809.1 - 3e-18 65.9 1.1 7.6e-18 64.6 0.8 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KFO99809.1 - 1.9e-17 62.8 0.2 6.2e-17 61.2 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFO99809.1 - 4.2e-16 58.8 0.5 9.4e-16 57.7 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KFO99809.1 - 6.2e-06 26.4 6.7 2e-05 24.8 1.0 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFO99809.1 - 0.00015 21.7 0.3 0.00032 20.7 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain C1_3 PF07649.7 KFO99809.1 - 0.001 19.0 2.7 0.001 19.0 1.8 2.8 2 0 0 2 2 2 1 C1-like domain C1_2 PF03107.11 KFO99809.1 - 0.015 15.4 4.5 0.015 15.4 3.1 2.7 3 0 0 3 3 3 0 C1 domain Mcp5_PH PF12814.2 KFO99809.1 - 0.036 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology AAA_5 PF07728.9 KFO99812.1 - 2.1e-100 332.0 0.0 2.8e-39 134.0 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 KFO99812.1 - 6.7e-10 39.3 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_16 PF13191.1 KFO99812.1 - 1.1e-08 35.3 1.1 0.21 11.5 0.0 5.6 4 1 0 5 5 5 2 AAA ATPase domain AAA_14 PF13173.1 KFO99812.1 - 7.8e-06 25.8 0.0 0.036 13.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 KFO99812.1 - 1.2e-05 25.5 0.2 0.019 15.1 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 KFO99812.1 - 4.1e-05 23.1 0.0 0.0076 15.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFO99812.1 - 0.00014 22.0 0.3 0.81 9.8 0.0 4.5 2 2 1 3 3 3 1 AAA domain VWA PF00092.23 KFO99812.1 - 0.00069 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.16 KFO99812.1 - 0.0014 17.8 0.3 2.9 6.9 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KFO99812.1 - 0.0027 17.6 0.0 0.64 9.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) CbbQ_C PF08406.5 KFO99812.1 - 0.005 16.8 0.0 3.3 7.7 0.0 2.7 2 0 0 2 2 2 1 CbbQ/NirQ/NorQ C-terminal AAA_17 PF13207.1 KFO99812.1 - 0.0066 17.2 0.0 0.07 13.9 0.0 2.9 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KFO99812.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFO99812.1 - 0.14 12.3 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 KFO99812.1 - 0.14 12.6 0.0 3.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein SMI1_KNR4 PF09346.5 KFO99812.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) ATP-synt_ab PF00006.20 KFO99812.1 - 0.15 11.5 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NARP1 PF12569.3 KFO99813.1 - 5.3e-214 711.7 20.6 5.3e-214 711.7 14.3 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KFO99813.1 - 1.2e-16 60.0 24.0 4.4e-07 29.4 0.3 8.0 5 2 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 KFO99813.1 - 2.4e-15 55.1 23.4 4.2e-05 23.1 0.1 8.4 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFO99813.1 - 5.3e-14 51.4 1.8 0.15 12.7 0.0 8.8 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO99813.1 - 2.2e-13 50.2 11.0 0.01 16.1 0.1 6.2 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFO99813.1 - 4.4e-11 43.1 14.0 0.0017 18.9 0.1 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFO99813.1 - 2.8e-10 39.9 14.8 0.039 13.9 0.1 7.4 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFO99813.1 - 1.2e-09 37.3 32.1 1.6e-05 24.3 0.4 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFO99813.1 - 8.2e-08 31.4 21.6 0.0012 18.4 0.1 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KFO99813.1 - 1.3e-07 31.6 23.8 0.00055 20.0 0.6 6.9 4 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFO99813.1 - 4.4e-06 25.9 0.2 4.4e-06 25.9 0.1 3.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFO99813.1 - 0.00042 19.9 13.4 0.011 15.5 0.1 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat MIT PF04212.13 KFO99813.1 - 0.00078 19.2 4.6 0.02 14.7 0.0 4.1 3 2 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 KFO99813.1 - 0.0033 17.2 9.2 0.28 11.0 0.3 5.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFO99813.1 - 0.0042 17.1 19.7 2.4 8.5 0.0 8.4 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO99813.1 - 0.02 15.3 10.7 19 5.9 0.1 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFO99813.1 - 0.025 14.5 5.4 26 4.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFO99813.1 - 0.03 14.7 0.0 1.2e+02 3.5 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFO99813.1 - 0.062 13.1 19.6 8 6.4 0.1 6.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat RF-1 PF00472.15 KFO99814.1 - 7.2e-40 135.3 2.2 1.9e-39 133.9 1.5 1.8 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KFO99814.1 - 1e-29 102.5 0.1 1e-29 102.5 0.1 2.6 3 1 0 3 3 3 1 PCRF domain CDI PF02234.14 KFO99814.1 - 0.024 14.4 0.0 0.14 11.9 0.0 2.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor SPOB_a PF14689.1 KFO99814.1 - 0.03 13.8 0.5 0.83 9.2 0.0 2.8 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain HisKA PF00512.20 KFO99814.1 - 0.24 11.4 8.8 0.84 9.6 1.0 3.6 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain WW PF00397.21 KFO99815.1 - 1.7e-18 66.1 22.9 1.3e-09 37.7 3.9 3.1 3 0 0 3 3 3 2 WW domain zf-U1 PF06220.7 KFO99815.1 - 2.6e-14 52.4 0.9 4.4e-14 51.7 0.6 1.4 1 0 0 1 1 1 1 U1 zinc finger PQQ PF01011.16 KFO99815.1 - 0.013 15.0 0.2 0.42 10.2 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat AKAP95 PF04988.7 KFO99815.1 - 0.28 10.9 5.6 0.3 10.8 0.1 2.3 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Elf-1_N PF12310.3 KFO99816.1 - 7.1e-36 122.4 1.3 2.2e-35 120.8 0.9 1.9 1 0 0 1 1 1 1 Transcription factor protein N terminal Ets PF00178.17 KFO99816.1 - 2.5e-35 120.4 2.4 3.8e-35 119.8 1.6 1.3 1 0 0 1 1 1 1 Ets-domain SGS PF05002.10 KFO99817.1 - 6.1e-29 99.6 2.5 6.1e-29 99.6 1.7 2.0 3 0 0 3 3 3 1 SGS domain CS PF04969.11 KFO99817.1 - 3.8e-19 69.0 2.9 4.7e-19 68.7 1.0 2.0 2 0 0 2 2 1 1 CS domain TPR_11 PF13414.1 KFO99817.1 - 1.9e-12 46.6 7.4 3e-09 36.3 1.8 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFO99817.1 - 2.7e-09 36.2 10.7 4.5e-06 26.1 2.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFO99817.1 - 3.6e-09 35.8 11.5 2.2e-06 27.0 3.4 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFO99817.1 - 2.1e-08 33.7 5.7 0.00012 21.9 0.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFO99817.1 - 0.00029 21.1 1.9 0.02 15.5 0.5 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFO99817.1 - 0.0049 17.4 6.3 0.032 14.9 2.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFO99817.1 - 0.0063 16.2 7.5 0.12 12.2 2.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFO99817.1 - 0.0068 16.4 2.3 0.021 14.9 0.4 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFO99817.1 - 0.0086 16.4 4.7 0.061 13.6 0.8 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFO99817.1 - 0.0096 15.7 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KFO99817.1 - 0.25 11.4 4.7 0.67 10.1 2.8 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFO99817.1 - 0.31 11.0 4.7 0.68 9.9 3.3 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat BRICHOS PF04089.9 KFO99818.1 - 1.6e-28 98.3 0.0 3.5e-28 97.3 0.0 1.6 2 0 0 2 2 2 1 BRICHOS domain Cadherin PF00028.12 KFO99819.1 - 6.8e-63 208.9 0.5 3.9e-15 55.8 0.0 5.3 4 1 1 5 5 5 5 Cadherin domain TMEM154 PF15102.1 KFO99819.1 - 0.0022 17.7 0.1 0.0045 16.7 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF1191 PF06697.7 KFO99819.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CD34_antigen PF06365.7 KFO99819.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.1 KFO99819.1 - 0.04 14.3 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OLF PF02191.11 KFO99820.1 - 1.2e-82 276.9 7.9 1.6e-82 276.5 5.5 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Tubulin-binding PF00418.14 KFO99821.1 - 1.7e-28 97.9 16.1 2e-15 56.1 2.3 2.0 2 0 0 2 2 2 2 Tau and MAP protein, tubulin-binding repeat Yae1_N PF09811.4 KFO99822.1 - 1.4e-15 56.5 56.5 1.5e+04 -22.6 39.2 5.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Cadherin PF00028.12 KFO99824.1 - 1.6e-92 303.9 0.0 5.9e-18 64.9 0.0 6.5 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.7 KFO99824.1 - 1.5e-16 59.7 0.1 4.6e-09 35.7 0.0 4.6 5 0 0 5 5 5 2 Cadherin-like DUF1767 PF08585.7 KFO99826.1 - 1.6e-20 73.1 0.0 3.9e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) SMN PF06003.7 KFO99826.1 - 6.4e-11 41.8 0.0 6.4e-11 41.8 0.0 2.6 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 KFO99826.1 - 7.2e-10 38.7 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Tudor domain UBA PF00627.26 KFO99826.1 - 6.5e-09 35.3 0.1 1.7e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Cadherin PF00028.12 KFO99827.1 - 5.4e-89 292.6 0.0 1.4e-19 70.0 0.0 7.2 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.7 KFO99827.1 - 6.7e-12 44.8 0.0 0.00028 20.3 0.0 5.8 5 1 0 5 5 5 2 Cadherin-like GRAM PF02893.15 KFO99829.1 - 1.4e-19 69.3 0.1 2.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain V-set PF07686.12 KFO99830.1 - 4.5e-17 61.9 0.2 5.6e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFO99830.1 - 7.2e-05 22.8 1.2 0.00022 21.2 0.8 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Herpes_gE PF02480.11 KFO99830.1 - 0.00045 18.6 1.2 0.089 11.0 0.1 2.1 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E I-set PF07679.11 KFO99830.1 - 0.00055 19.7 0.2 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99830.1 - 0.002 18.1 0.2 0.0047 17.0 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin domain EII-GUT PF03608.8 KFO99830.1 - 0.0061 16.4 0.2 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 PTS system enzyme II sorbitol-specific factor Ig_3 PF13927.1 KFO99830.1 - 0.025 15.0 1.1 0.24 11.9 0.8 2.2 1 1 0 1 1 1 0 Immunoglobulin domain OAD_gamma PF04277.8 KFO99830.1 - 0.04 14.2 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF843 PF05814.6 KFO99830.1 - 0.05 13.4 0.2 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) E1-E2_ATPase PF00122.15 KFO99831.1 - 5.6e-60 202.2 3.2 1.6e-59 200.7 2.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFO99831.1 - 3.3e-42 144.0 1.3 3.3e-42 144.0 0.9 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFO99831.1 - 3.3e-30 106.1 0.0 7.4e-30 104.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFO99831.1 - 1.1e-26 92.5 0.0 3e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFO99831.1 - 1.2e-16 59.8 0.0 2.6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFO99831.1 - 1.5e-16 61.1 0.0 3.4e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFO99831.1 - 6.9e-07 29.0 1.9 0.00041 20.0 0.8 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cytidylate_kin2 PF13189.1 KFO99831.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family Sigma70_r4 PF04545.11 KFO99831.1 - 0.17 11.1 0.0 0.45 9.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 AKAP_110 PF05716.8 KFO99833.1 - 9.2e-10 37.1 0.0 9.2e-10 37.1 0.0 2.0 2 0 0 2 2 2 1 A-kinase anchor protein 110 kDa (AKAP 110) WD40 PF00400.27 KFO99834.1 - 1.4e-84 275.2 20.9 1e-10 41.0 0.2 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 KFO99834.1 - 6.5e-08 31.1 0.3 0.11 10.5 0.0 5.1 3 2 2 5 5 5 2 Nucleoporin Nup120/160 DUF1258 PF06869.7 KFO99834.1 - 0.011 14.8 3.1 0.62 9.1 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 KFO99834.1 - 0.038 13.4 0.1 0.29 10.5 0.0 2.2 2 2 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 KFO99834.1 - 0.057 12.1 0.9 11 4.6 0.3 3.0 1 1 2 3 3 3 0 Nup133 N terminal like IL8 PF00048.15 KFO99835.1 - 2.3e-18 65.9 0.1 2.7e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Folate_carrier PF01770.13 KFO99836.1 - 9.2e-150 498.7 17.2 1.8e-93 313.3 0.2 2.0 1 1 1 2 2 2 2 Reduced folate carrier MFS_1 PF07690.11 KFO99836.1 - 1.5e-05 23.8 3.7 1.5e-05 23.8 2.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ArfGap PF01412.13 KFO99837.1 - 8.2e-12 44.9 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf dsrm PF00035.20 KFO99838.1 - 0.0014 19.1 0.0 0.0026 18.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KFO99838.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease-III-like Miff PF05644.6 KFO99839.1 - 4e-38 131.4 0.6 6.8e-38 130.6 0.4 1.5 1 1 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff KTI12 PF08433.5 KFO99839.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SPATA19 PF15212.1 KFO99839.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 19, mitochondrial Collagen PF01391.13 KFO99840.1 - 1.9e-186 603.8 690.2 4.5e-10 38.9 13.2 27.0 9 7 16 25 25 25 25 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFO99840.1 - 3.2e-91 300.9 4.5 1.6e-47 160.0 0.5 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Collagen PF01391.13 KFO99841.1 - 2.5e-180 584.2 695.0 3.7e-10 39.1 15.3 28.1 7 6 18 25 25 25 24 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFO99841.1 - 9.5e-85 280.0 4.0 2.8e-44 149.6 0.6 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Rhomboid PF01694.17 KFO99842.1 - 1.3e-14 54.4 5.9 1.3e-14 54.4 4.1 1.6 2 0 0 2 2 2 1 Rhomboid family COPI_assoc PF08507.5 KFO99842.1 - 6.8 6.3 8.5 0.13 11.9 0.8 2.0 3 0 0 3 3 3 0 COPI associated protein IRS PF02174.12 KFO99843.1 - 1.7e-29 101.3 0.0 2.7e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 KFO99843.1 - 2.3e-14 53.4 0.1 5.5e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFO99843.1 - 0.0004 20.6 0.1 0.00076 19.7 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 KFO99843.1 - 0.085 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology NYAP_N PF15439.1 KFO99844.1 - 2.7e-93 313.1 37.3 1.5e-84 284.3 15.9 4.6 4 1 1 5 5 5 3 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter NYAP_C PF15452.1 KFO99844.1 - 6.3e-13 48.4 7.0 1e-12 47.7 4.9 1.3 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Guanylate_cyc PF00211.15 KFO99845.1 - 1.1e-67 226.9 0.1 1.7e-67 226.3 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.10 KFO99845.1 - 5.6e-41 139.9 0.2 1.1e-40 138.9 0.1 1.5 1 0 0 1 1 1 1 Heme NO binding HNOBA PF07701.9 KFO99845.1 - 8.3e-41 139.6 14.3 2e-22 79.5 4.0 2.7 3 0 0 3 3 3 2 Heme NO binding associated DIRP PF06584.8 KFO99845.1 - 0.26 11.1 2.1 0.45 10.4 0.4 2.1 2 0 0 2 2 2 0 DIRP Cullin PF00888.17 KFO99846.1 - 2.1e-202 673.8 10.7 2.5e-202 673.5 7.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFO99846.1 - 5.9e-30 102.8 2.0 2.5e-29 100.8 1.4 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain FAM124 PF15067.1 KFO99847.1 - 2.3e-101 338.1 0.2 2.5e-101 338.0 0.2 1.0 1 0 0 1 1 1 1 FAM124 family Serpin PF00079.15 KFO99848.1 - 9.9e-105 350.7 0.1 1.1e-104 350.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) WD40 PF00400.27 KFO99849.1 - 3.7e-29 99.5 15.5 5.5e-09 35.5 0.4 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat FYVE PF01363.16 KFO99849.1 - 2.1e-15 56.3 7.9 5.4e-15 55.0 5.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.19 KFO99849.1 - 1.3 8.9 12.6 0.12 12.3 0.7 4.0 4 0 0 4 4 4 0 B-box zinc finger FYVE_2 PF02318.11 KFO99849.1 - 1.8 8.4 8.2 5.2 7.0 5.7 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger Yae1_N PF09811.4 KFO99851.1 - 1.1e-19 69.6 49.6 1.5e+04 -12.5 34.4 5.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Vinculin PF01044.14 KFO99852.1 - 0 1062.3 41.0 8.7e-220 732.3 16.9 2.1 1 1 1 2 2 2 2 Vinculin family CorA PF01544.13 KFO99852.1 - 0.46 9.4 3.4 1.3 7.9 0.0 2.9 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF948 PF06103.6 KFO99852.1 - 1.6 8.6 9.3 1.9 8.3 0.1 4.3 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) LRR_8 PF13855.1 KFO99853.1 - 3.6e-53 177.1 27.2 8.7e-16 57.4 0.5 5.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFO99853.1 - 5.4e-30 102.4 18.3 4.3e-07 29.3 0.1 7.0 3 3 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFO99853.1 - 6.5e-21 71.1 23.6 0.067 13.2 0.2 11.3 12 0 0 12 12 12 6 Leucine Rich Repeat LRR_5 PF13306.1 KFO99853.1 - 5.3e-20 71.4 0.0 9.8e-10 38.2 0.0 2.7 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFO99853.1 - 3.5e-12 44.4 17.4 0.55 10.6 0.0 10.6 11 0 0 11 11 10 3 Leucine rich repeat LRR_9 PF14580.1 KFO99853.1 - 5e-09 35.9 0.7 0.014 14.9 0.0 3.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 KFO99853.1 - 1.2e-07 31.0 24.9 1.8 8.9 0.0 10.2 10 1 1 11 11 10 2 Leucine Rich repeat LRRNT PF01462.13 KFO99853.1 - 4.5e-05 22.7 1.5 4.5e-05 22.7 1.1 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain UL97 PF06734.7 KFO99853.1 - 0.047 13.0 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 UL97 Pyrid_oxidase_2 PF13883.1 KFO99853.1 - 0.063 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase HemY_N PF07219.8 KFO99853.1 - 0.073 12.6 0.2 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Yae1_N PF09811.4 KFO99854.1 - 2.3e-21 75.0 59.0 1.5e+04 -21.0 40.9 5.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MmgE_PrpD PF03972.9 KFO99855.1 - 8.9e-65 218.5 0.0 1.1e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DJ-1_PfpI PF01965.19 KFO99856.1 - 1.1e-11 44.3 0.7 1.7e-11 43.8 0.5 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.1 KFO99856.1 - 0.056 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CLN5 PF15014.1 KFO99857.1 - 1.9e-175 582.4 3.4 2.1e-175 582.2 2.4 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Lipase3_N PF03893.11 KFO99857.1 - 0.037 13.8 0.3 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 Lipase 3 N-terminal region EIIA-man PF03610.11 KFO99857.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component F-box-like PF12937.2 KFO99858.1 - 1.4e-08 34.2 3.0 2.6e-08 33.4 0.5 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KFO99858.1 - 2.2e-08 33.5 2.6 2.6e-08 33.2 0.1 2.5 3 0 0 3 3 3 1 F-box domain DUF4116 PF13475.1 KFO99858.1 - 0.0084 15.5 0.4 0.024 14.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) SPRY PF00622.23 KFO99859.1 - 1.2e-18 67.3 0.0 1.8e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.11 KFO99859.1 - 1.7e-13 50.1 3.9 3.4e-13 49.2 2.7 1.5 1 0 0 1 1 1 1 SOCS box Cadherin PF00028.12 KFO99860.1 - 1.4e-15 57.3 0.2 5.2e-10 39.4 0.3 2.7 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.1 KFO99860.1 - 6.3e-09 36.2 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1510 PF07423.6 KFO99860.1 - 0.0002 20.7 10.8 0.00033 20.1 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Glyco_hydro_16 PF00722.16 KFO99860.1 - 0.0089 15.3 0.6 0.032 13.5 0.4 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Protocadherin PF08374.6 KFO99860.1 - 0.014 15.0 0.4 0.023 14.3 0.3 1.3 1 0 0 1 1 1 0 Protocadherin DUF2207 PF09972.4 KFO99860.1 - 0.02 13.5 0.1 0.55 8.7 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Chordopox_A13L PF05961.6 KFO99860.1 - 0.065 13.1 0.7 0.19 11.7 0.1 2.0 1 1 1 2 2 2 0 Chordopoxvirus A13L protein Ycf1 PF05758.7 KFO99860.1 - 0.084 10.5 3.2 0.13 9.9 2.2 1.1 1 0 0 1 1 1 0 Ycf1 EphA2_TM PF14575.1 KFO99860.1 - 0.17 12.3 1.3 1.7 9.0 0.1 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Myc_N PF01056.13 KFO99860.1 - 6.9 5.7 15.3 11 5.0 10.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CTP_transf_2 PF01467.21 KFO99861.1 - 5.8e-40 136.9 0.0 1.6e-39 135.5 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase DUF1126 PF06565.7 KFO99861.1 - 0.046 13.2 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1126) Lipocalin PF00061.18 KFO99862.1 - 5.9e-18 65.2 0.3 6.4e-18 65.1 0.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFO99862.1 - 1.9e-05 24.3 0.2 2.4e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFO99863.1 - 1.2e-17 64.2 6.0 1.3e-17 64.1 4.2 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFO99863.1 - 2.1e-06 27.4 0.5 2.5e-06 27.2 0.3 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Coatomer_WDAD PF04053.9 KFO99864.1 - 6.5e-169 562.4 0.0 1.1e-168 561.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KFO99864.1 - 4.5e-56 184.8 6.1 4.3e-13 48.5 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat MRP-S22 PF10245.4 KFO99865.1 - 2.8e-96 321.6 3.9 3.9e-96 321.1 2.7 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 FAD_binding_9 PF08021.6 KFO99865.1 - 0.084 12.8 0.1 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Fork_head PF00250.13 KFO99866.1 - 2.3e-41 139.7 0.1 3.7e-41 139.0 0.1 1.3 1 0 0 1 1 1 1 Fork head domain PI3Ka PF00613.15 KFO99867.1 - 3.7e-62 208.8 1.3 8.1e-62 207.6 0.9 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFO99867.1 - 6.8e-58 195.9 0.0 1.2e-57 195.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_p85B PF02192.11 KFO99867.1 - 5.8e-37 124.9 0.1 3.4e-36 122.4 0.0 2.3 2 0 0 2 2 2 1 PI3-kinase family, p85-binding domain PI3K_rbd PF00794.13 KFO99867.1 - 3e-31 107.5 0.1 7.1e-31 106.3 0.1 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 KFO99867.1 - 5.1e-25 87.9 0.0 9.5e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 RWD PF05773.17 KFO99867.1 - 0.05 13.5 0.0 1.5 8.7 0.0 2.9 2 0 0 2 2 2 0 RWD domain Synaptobrevin PF00957.16 KFO99869.1 - 3.2e-22 77.9 1.0 3.4e-22 77.8 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin Seryl_tRNA_N PF02403.17 KFO99869.1 - 0.031 14.2 0.2 0.035 14.1 0.1 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Period_C PF12114.3 KFO99870.1 - 4.7e-80 267.7 5.0 4.7e-80 267.7 3.4 4.5 4 1 0 4 4 4 1 Period protein 2/3C-terminal region PAS_11 PF14598.1 KFO99870.1 - 4.6e-12 45.8 0.0 2.5e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 KFO99870.1 - 1.4e-09 37.8 0.0 6.6e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KFO99870.1 - 1.8e-07 30.9 0.0 0.00017 21.3 0.0 3.0 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFO99871.1 - 2.1e-14 52.9 1.6 4.2e-14 51.9 1.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFO99871.1 - 5.5e-14 51.6 0.1 1.2e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Hairy Orange Mo25 PF08569.6 KFO99872.1 - 4.6e-145 482.8 14.7 5.2e-145 482.6 10.2 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 KFO99872.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats BRICHOS PF04089.9 KFO99873.1 - 3e-29 100.7 0.0 4.3e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 BRICHOS domain 7tm_1 PF00001.16 KFO99874.1 - 2.6e-37 128.3 17.9 3e-37 128.1 12.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-C2HC_2 PF13913.1 KFO99875.1 - 1.4e-18 66.0 10.1 4.4e-11 42.1 0.6 2.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KFO99875.1 - 0.0004 20.5 5.3 0.013 15.8 0.1 2.7 3 0 0 3 3 2 2 Zinc finger, C2H2 type Sgf11 PF08209.6 KFO99875.1 - 0.0067 15.7 0.4 0.25 10.6 0.0 2.4 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) c-SKI_SMAD_bind PF08782.5 KFO99875.1 - 0.015 15.3 0.5 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 c-SKI Smad4 binding domain zinc_ribbon_4 PF13717.1 KFO99875.1 - 0.035 13.7 1.4 3.4 7.4 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFO99875.1 - 0.049 13.2 1.2 4.5 6.9 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFO99875.1 - 0.11 11.7 1.3 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rad50_zn_hook PF04423.9 KFO99875.1 - 0.15 11.5 0.1 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.3 KFO99875.1 - 0.16 12.1 0.4 9.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCHC PF00098.18 KFO99875.1 - 0.28 11.1 3.9 4.5 7.3 0.3 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2_2 PF13465.1 KFO99875.1 - 0.29 11.5 2.5 3.7 8.0 0.2 2.8 2 1 0 2 2 2 0 Zinc-finger double domain Prok-RING_1 PF14446.1 KFO99875.1 - 0.37 10.5 2.0 5.9 6.7 0.0 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_6 PF13912.1 KFO99875.1 - 0.58 10.1 5.7 11 6.1 0.6 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger DZR PF12773.2 KFO99875.1 - 0.59 10.0 3.8 3.8 7.3 2.6 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HC_2 PF13913.1 KFO99876.1 - 2.4e-22 78.0 4.9 9.2e-12 44.3 0.3 2.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KFO99876.1 - 0.00087 19.5 3.8 0.016 15.5 0.1 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type Sgf11 PF08209.6 KFO99876.1 - 0.0047 16.1 0.5 0.7 9.2 0.0 2.3 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) Lar_restr_allev PF14354.1 KFO99876.1 - 0.012 15.9 1.0 5.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-H2C2_2 PF13465.1 KFO99876.1 - 0.21 11.9 1.0 2.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Prok-RING_1 PF14446.1 KFO99876.1 - 0.52 10.0 3.4 1.9 8.2 0.1 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4428 PF14471.1 KFO99876.1 - 1.7 8.4 5.7 3.6 7.4 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2H2_4 PF13894.1 KFO99876.1 - 4 7.9 6.7 9.6 6.8 0.5 3.0 2 2 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.2 KFO99877.1 - 5.1e-20 71.6 3.3 6.5e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFO99877.1 - 6.1e-17 61.6 0.2 3e-07 30.7 0.0 3.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFO99877.1 - 1.7e-14 53.4 2.1 0.00011 22.3 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFO99877.1 - 1.5e-13 49.7 3.1 4.7e-07 29.2 0.2 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KFO99877.1 - 7.6e-08 31.8 0.8 0.029 14.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Vps5 PF09325.5 KFO99878.1 - 2.5e-85 285.4 19.2 2.5e-85 285.4 13.3 1.4 2 0 0 2 2 2 1 Vps5 C terminal like Sorting_nexin PF03700.8 KFO99878.1 - 1.2e-32 112.6 4.4 2.5e-32 111.6 3.1 1.6 1 0 0 1 1 1 1 Sorting nexin, N-terminal domain PX PF00787.19 KFO99878.1 - 6.7e-30 103.1 0.4 1.9e-28 98.5 0.1 2.4 2 0 0 2 2 2 1 PX domain FAM92 PF06730.6 KFO99878.1 - 0.0011 18.3 7.1 0.0023 17.3 4.9 1.5 1 0 0 1 1 1 1 FAM92 protein SH3BP5 PF05276.9 KFO99878.1 - 0.009 15.3 8.0 0.27 10.5 0.2 2.7 3 0 0 3 3 3 2 SH3 domain-binding protein 5 (SH3BP5) Spc7 PF08317.6 KFO99878.1 - 0.17 10.5 15.8 0.12 11.0 2.8 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KFO99878.1 - 0.18 10.9 3.2 0.14 11.2 0.7 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 KFO99878.1 - 0.27 10.3 16.8 0.019 14.0 2.8 2.3 2 0 0 2 2 2 0 Tropomyosin GAS PF13851.1 KFO99878.1 - 0.42 9.7 18.4 0.24 10.5 3.0 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3138 PF11336.3 KFO99878.1 - 0.49 8.5 3.6 0.76 7.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HR1 PF02185.11 KFO99878.1 - 0.94 9.2 11.1 2.3 8.0 0.2 3.5 3 0 0 3 3 3 0 Hr1 repeat SpaB_C PF14028.1 KFO99878.1 - 1.2 8.6 6.5 2.4 7.6 4.4 1.6 1 1 0 1 1 1 0 SpaB C-terminal domain Seryl_tRNA_N PF02403.17 KFO99878.1 - 1.3 9.0 14.9 3.4 7.7 2.7 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF848 PF05852.6 KFO99878.1 - 2.5 7.9 14.4 0.52 10.1 3.5 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Allexi_40kDa PF05549.6 KFO99878.1 - 5.3 6.2 8.4 0.7 9.1 0.5 2.6 2 1 1 3 3 3 0 Allexivirus 40kDa protein 4HB_MCP_1 PF12729.2 KFO99878.1 - 6.1 6.1 11.9 0.84 8.9 1.7 2.8 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction FliD_N PF02465.13 KFO99878.1 - 6.8 7.1 12.7 0.25 11.7 1.9 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DivIC PF04977.10 KFO99878.1 - 6.9 6.2 14.9 31 4.1 0.1 3.6 3 0 0 3 3 3 0 Septum formation initiator GrpE PF01025.14 KFO99878.1 - 7.9 5.9 18.0 0.11 11.9 4.0 2.6 2 1 0 2 2 2 0 GrpE PX PF00787.19 KFO99879.1 - 9.4e-14 51.1 3.4 2.9e-13 49.6 1.8 1.9 1 1 1 2 2 2 2 PX domain Pro_isomerase PF00160.16 KFO99880.1 - 1.7e-45 155.0 0.2 1.9e-45 154.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.21 KFO99881.1 - 5.8e-13 48.3 19.3 3.8e-05 23.7 1.0 4.5 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO99881.1 - 1.6e-12 47.0 19.1 4e-05 23.6 0.1 5.0 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO99881.1 - 8e-10 38.3 18.1 0.0011 19.1 1.0 4.5 4 0 0 4 4 3 3 C2H2-type zinc finger SET PF00856.23 KFO99881.1 - 2.4e-07 31.2 0.2 3.8e-06 27.3 0.1 2.4 1 1 0 1 1 1 1 SET domain zf-H2C2_5 PF13909.1 KFO99881.1 - 0.0016 18.5 3.7 0.0085 16.2 1.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KFO99881.1 - 0.0046 16.8 9.3 0.47 10.4 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO99881.1 - 0.0096 16.0 4.4 0.027 14.5 0.0 3.1 3 0 0 3 3 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFO99881.1 - 0.065 13.0 5.0 0.51 10.1 0.1 3.3 3 0 0 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.1 KFO99881.1 - 0.23 11.1 0.0 0.23 11.1 0.0 4.0 5 0 0 5 5 4 0 zinc-finger of a C2HC-type SprT-like PF10263.4 KFO99881.1 - 0.29 10.7 5.6 1.1 8.8 2.3 2.6 2 1 0 2 2 2 0 SprT-like family zf-CHCC PF10276.4 KFO99881.1 - 0.54 10.1 4.9 0.52 10.2 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.7 KFO99881.1 - 1.4 9.0 0.0 1.4 9.0 0.0 4.0 3 1 1 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFO99881.1 - 2.3 8.3 7.9 18 5.5 0.0 3.7 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 KFO99881.1 - 9.9 4.5 10.3 5.3 5.4 2.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF629) DUF3668 PF12416.3 KFO99882.1 - 9.3e-120 399.8 0.0 9.3e-120 399.8 0.0 2.7 3 1 0 3 3 3 1 Cep120 protein Pkinase PF00069.20 KFO99883.1 - 4.6e-35 121.0 0.0 6.4e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.3 KFO99883.1 - 4.5e-21 75.2 5.4 8.2e-21 74.3 3.7 1.4 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.12 KFO99883.1 - 1.5e-14 53.7 0.0 1.9e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.22 KFO99888.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GRAM PF02893.15 KFO99889.1 - 7.6e-14 50.9 0.2 1.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 GRAM domain DUF1724 PF08350.5 KFO99889.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) Aldedh PF00171.17 KFO99890.1 - 9.8e-124 413.1 0.0 1.1e-123 413.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 KFO99890.1 - 0.1 12.2 0.4 0.22 11.1 0.1 1.7 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF1211 PF06736.6 KFO99891.1 - 8.3e-48 160.4 12.7 6.1e-32 109.6 0.0 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF1211) Chordopox_A13L PF05961.6 KFO99891.1 - 0.0075 16.1 0.2 0.021 14.7 0.1 1.8 1 0 0 1 1 1 1 Chordopoxvirus A13L protein PDEase_I PF00233.14 KFO99892.1 - 3.7e-94 314.9 4.4 8.2e-94 313.7 3.0 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFO99892.1 - 1.4e-40 138.9 0.0 6.8e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFO99892.1 - 2e-13 50.5 0.0 4.9e-06 26.6 0.0 2.7 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.1 KFO99892.1 - 9.4e-09 35.9 0.0 0.00032 21.2 0.0 2.3 2 0 0 2 2 2 2 GAF domain DUF4316 PF14195.1 KFO99892.1 - 0.047 13.7 0.3 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Cut12 PF11500.3 KFO99892.1 - 0.051 13.2 2.3 0.053 13.2 0.2 2.0 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Lipocalin PF00061.18 KFO99893.1 - 1e-17 64.4 0.0 1.3e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.7 KFO99893.1 - 1e-09 38.3 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.8 KFO99893.1 - 8.2e-06 25.5 0.1 0.00084 19.0 0.0 2.2 2 0 0 2 2 2 2 Triabin Glyco_hydro_39 PF01229.12 KFO99894.1 - 2.5e-149 497.8 0.1 3e-149 497.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Sulfate_transp PF00916.15 KFO99895.1 - 1.7e-70 237.1 14.8 1.7e-70 237.1 10.2 2.1 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFO99895.1 - 8.1e-29 99.1 3.0 8.1e-29 99.1 2.1 3.6 4 1 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFO99895.1 - 4e-26 90.7 0.0 7.6e-26 89.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain Neur_chan_LBD PF02931.18 KFO99896.1 - 2.1e-75 252.6 2.7 2.6e-75 252.2 1.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFO99896.1 - 3.1e-57 194.1 9.1 4.1e-57 193.7 6.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1286 PF06939.6 KFO99896.1 - 0.018 15.1 1.0 0.018 15.1 0.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1286) DUF2417 PF10329.4 KFO99896.1 - 0.021 14.2 4.5 0.035 13.5 3.1 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Neur_chan_LBD PF02931.18 KFO99897.1 - 2.1e-72 242.8 0.1 3.4e-72 242.1 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFO99897.1 - 8.4e-59 199.3 12.1 5.9e-56 190.0 8.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM_3 PF13706.1 KFO99897.1 - 5.1 6.6 10.9 0.14 11.5 1.4 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix THAP PF05485.7 KFO99898.1 - 1.5e-16 60.2 0.9 4.4e-16 58.8 0.6 1.7 1 0 0 1 1 1 1 THAP domain Cep57_CLD PF14073.1 KFO99898.1 - 8.7e-05 22.4 3.7 0.00013 21.8 2.5 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 DUF4391 PF14335.1 KFO99898.1 - 0.0035 16.7 2.4 0.0051 16.2 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) RTBV_P46 PF06216.6 KFO99898.1 - 0.0036 16.2 0.4 0.0046 15.8 0.3 1.1 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein 7TMR-HDED PF07697.6 KFO99898.1 - 0.0042 16.8 1.2 0.0061 16.3 0.8 1.2 1 0 0 1 1 1 1 7TM-HD extracellular ADIP PF11559.3 KFO99898.1 - 0.0046 16.8 9.6 0.0068 16.3 6.7 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Macoilin PF09726.4 KFO99898.1 - 0.006 14.9 3.8 0.0081 14.5 2.7 1.1 1 0 0 1 1 1 1 Transmembrane protein Mitofilin PF09731.4 KFO99898.1 - 0.009 14.7 0.2 0.012 14.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Tropomyosin_1 PF12718.2 KFO99898.1 - 0.012 15.4 4.8 0.022 14.6 3.3 1.3 1 0 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.15 KFO99898.1 - 0.012 14.6 6.5 0.018 14.1 4.5 1.1 1 0 0 1 1 1 0 Tropomyosin GrpE PF01025.14 KFO99898.1 - 0.015 14.8 3.4 0.023 14.2 2.4 1.2 1 0 0 1 1 1 0 GrpE L31 PF09784.4 KFO99898.1 - 0.017 15.1 1.9 0.03 14.3 1.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF4140 PF13600.1 KFO99898.1 - 0.029 14.7 0.7 0.042 14.2 0.5 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3373 PF11853.3 KFO99898.1 - 0.053 12.0 1.3 0.068 11.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) FemAB PF02388.11 KFO99898.1 - 0.054 12.1 1.0 0.072 11.7 0.7 1.1 1 0 0 1 1 1 0 FemAB family YPEB PF14620.1 KFO99898.1 - 0.063 12.2 2.3 0.088 11.8 1.6 1.1 1 0 0 1 1 1 0 YpeB sporulation AAA_27 PF13514.1 KFO99898.1 - 0.065 10.9 3.2 0.08 10.6 2.2 1.0 1 0 0 1 1 1 0 AAA domain DUF607 PF04678.8 KFO99898.1 - 0.073 12.9 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 IncA PF04156.9 KFO99898.1 - 0.12 11.9 5.5 0.17 11.4 3.8 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KFO99898.1 - 0.13 11.8 7.1 0.22 11.0 4.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Vac_Fusion PF02346.11 KFO99898.1 - 0.16 11.3 3.7 0.3 10.5 2.5 1.4 1 0 0 1 1 1 0 Chordopoxvirus fusion protein FliD_C PF07195.7 KFO99898.1 - 0.17 11.1 1.4 0.23 10.7 0.9 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Atg14 PF10186.4 KFO99898.1 - 0.25 10.2 10.8 0.37 9.6 7.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EAP30 PF04157.11 KFO99898.1 - 0.26 10.4 3.3 0.35 10.0 2.3 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family CCDC-167 PF15188.1 KFO99898.1 - 0.32 10.9 4.0 0.56 10.1 2.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 APG6 PF04111.7 KFO99898.1 - 0.32 9.9 4.0 0.45 9.5 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2951 PF11166.3 KFO99898.1 - 0.33 10.8 6.6 0.58 10.0 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) ABC_tran_2 PF12848.2 KFO99898.1 - 0.46 10.3 9.3 0.84 9.5 6.5 1.4 1 0 0 1 1 1 0 ABC transporter TMF_DNA_bd PF12329.3 KFO99898.1 - 0.53 10.1 7.0 0.94 9.3 4.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 KFO99898.1 - 0.56 10.1 3.4 0.94 9.4 2.3 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) 4HBT_3 PF13622.1 KFO99898.1 - 0.92 9.1 9.6 1.3 8.6 6.7 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily XhlA PF10779.4 KFO99898.1 - 1.8 8.5 4.4 2.7 7.9 3.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA AKNA PF12443.3 KFO99898.1 - 1.9 8.5 7.8 5.4 7.0 5.4 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF3391 PF11871.3 KFO99898.1 - 4.5 7.4 8.2 5.4e+02 0.7 5.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF605 PF04652.11 KFO99898.1 - 4.9 6.4 13.1 5.5 6.2 9.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF1232 PF06803.7 KFO99899.1 - 5.8e-10 38.4 8.6 5.8e-10 38.4 5.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) zf-C3HC4_3 PF13920.1 KFO99899.1 - 4.5e-09 35.8 2.6 6.5e-09 35.3 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO99899.1 - 7.2e-09 35.1 3.8 1.2e-08 34.4 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO99899.1 - 9.1e-09 35.2 6.9 1.4e-08 34.5 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFO99899.1 - 1.8e-08 34.1 4.6 4.2e-08 32.9 3.2 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFO99899.1 - 1.9e-08 34.0 6.7 3e-08 33.3 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFO99899.1 - 1.8e-06 27.5 4.4 3.5e-06 26.6 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFO99899.1 - 5.5e-06 26.0 1.2 5.5e-06 26.0 0.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 KFO99899.1 - 0.011 15.1 1.4 0.02 14.3 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KFO99899.1 - 0.034 13.9 2.2 0.062 13.1 1.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFO99899.1 - 0.082 13.0 2.3 0.15 12.2 1.6 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger Cys_rich_CPXG PF14255.1 KFO99899.1 - 0.09 12.6 0.9 8.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-MIZ PF02891.15 KFO99899.1 - 1.3 8.5 8.4 2.7 7.5 5.9 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DRP PF06044.7 KFO99899.1 - 1.4 7.8 3.3 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Dam-replacing family Baculo_IE-1 PF05290.6 KFO99899.1 - 1.6 8.4 4.0 3.3 7.4 2.8 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-met2 PF12907.2 KFO99899.1 - 9.7 6.2 7.9 9.4 6.3 0.6 3.0 3 0 0 3 3 3 0 Zinc-binding HOOK PF05622.7 KFO99900.1 - 0 1079.8 80.1 0 1079.6 55.5 1.0 1 0 0 1 1 1 1 HOOK protein HALZ PF02183.13 KFO99900.1 - 0.0003 20.4 3.2 0.0003 20.4 2.2 9.6 9 2 2 11 11 11 2 Homeobox associated leucine zipper Filament PF00038.16 KFO99900.1 - 0.006 16.0 35.6 0.006 16.0 24.7 4.7 3 1 1 4 4 4 1 Intermediate filament protein Reo_sigmaC PF04582.7 KFO99900.1 - 0.036 13.2 24.8 0.045 12.9 1.0 3.9 3 1 1 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFO99900.1 - 3.4 6.0 67.0 0.11 10.8 16.8 3.3 3 0 0 3 3 3 0 AAA domain GAS PF13851.1 KFO99900.1 - 3.4 6.7 103.9 0.33 10.1 12.9 6.6 3 2 4 7 7 7 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 KFO99900.1 - 3.6 7.0 102.0 5.5 6.4 17.0 4.9 2 1 2 5 5 5 0 Ezrin/radixin/moesin family NPV_P10 PF05531.7 KFO99900.1 - 6.6 7.0 42.4 2.1 8.6 0.1 8.5 5 3 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Myosin_tail_1 PF01576.14 KFO99900.1 - 9.9 3.7 106.8 0.12 10.0 27.1 3.9 1 1 2 3 3 3 0 Myosin tail zf-Di19 PF05605.7 KFO99901.1 - 1.3e-22 79.6 1.7 1.3e-22 79.6 1.2 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.12 KFO99901.1 - 1.4e-10 40.5 7.1 1.4e-10 40.5 4.9 2.5 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-C2H2_4 PF13894.1 KFO99901.1 - 0.0081 16.4 0.1 0.0081 16.4 0.1 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger Di19_C PF14571.1 KFO99901.1 - 0.0089 16.3 3.4 0.0089 16.3 2.3 2.4 1 1 1 2 2 2 1 Stress-induced protein Di19, C-terminal zf-C2H2 PF00096.21 KFO99901.1 - 0.014 15.7 0.3 0.014 15.7 0.2 3.3 3 1 0 3 3 3 0 Zinc finger, C2H2 type Dicty_REP PF05086.7 KFO99901.1 - 0.028 12.2 4.0 0.036 11.8 2.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-ribbon_3 PF13248.1 KFO99901.1 - 0.17 11.1 2.3 2.5 7.4 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 KFO99901.1 - 0.35 11.0 0.1 0.35 11.0 0.1 2.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-LITAF-like PF10601.4 KFO99901.1 - 2.7 7.9 11.2 0.37 10.6 0.2 3.4 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain PPTA PF01239.17 KFO99902.1 - 7.3e-52 170.6 14.5 3.9e-12 44.9 0.2 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 KFO99902.1 - 1.5 8.3 11.8 14 5.2 0.1 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4219) Glyco_transf_10 PF00852.14 KFO99903.1 - 1e-90 303.8 3.8 1.3e-90 303.5 2.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Neuregulin PF02158.10 KFO99904.1 - 1.1e-235 781.8 27.5 1.5e-235 781.3 19.1 1.2 1 0 0 1 1 1 1 Neuregulin family I-set PF07679.11 KFO99904.1 - 6.7e-15 54.7 0.7 3.1e-14 52.5 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFO99904.1 - 7.9e-11 41.9 0.4 3.5e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.10 KFO99904.1 - 5e-06 26.4 1.8 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Ig_3 PF13927.1 KFO99904.1 - 1.1e-05 25.7 7.7 7.4e-05 23.1 0.0 3.4 3 1 1 4 4 3 1 Immunoglobulin domain ig PF00047.20 KFO99904.1 - 1.4e-05 25.1 0.2 6.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFO99904.1 - 2.6e-05 24.0 0.1 2.6e-05 24.0 0.1 2.7 3 0 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFO99904.1 - 9.3e-05 22.2 2.3 0.00058 19.7 0.0 2.8 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain hEGF PF12661.2 KFO99904.1 - 0.0087 16.0 1.6 0.017 15.1 1.1 1.5 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 KFO99904.1 - 0.22 11.7 3.6 0.56 10.4 2.5 1.7 1 1 0 1 1 1 0 EGF-like domain EGF PF00008.22 KFO99904.1 - 0.25 11.3 3.3 0.68 9.9 2.3 1.8 1 1 0 1 1 1 0 EGF-like domain DUF3650 PF12368.3 KFO99904.1 - 3.9 7.0 6.3 4.2 6.9 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) Thioredoxin PF00085.15 KFO99905.1 - 1.3e-83 275.3 0.2 8.4e-31 105.7 0.0 3.0 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.1 KFO99905.1 - 2.1e-15 56.8 5.5 0.0013 18.8 0.0 5.4 3 3 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFO99905.1 - 2.9e-12 46.5 2.0 0.017 15.2 0.0 5.0 3 3 3 6 6 6 3 Thioredoxin-like Thioredoxin_6 PF13848.1 KFO99905.1 - 8.7e-10 38.7 0.0 0.009 15.8 0.0 3.2 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFO99905.1 - 6.4e-07 29.3 1.8 0.49 10.4 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin-like HyaE PF07449.6 KFO99905.1 - 1.1e-05 25.2 0.0 0.031 14.1 0.0 3.0 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KFO99905.1 - 6.4e-05 22.6 0.1 4.3 7.2 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin domain TraF PF13728.1 KFO99905.1 - 0.00012 21.6 0.3 1.5 8.2 0.0 3.7 3 2 1 4 4 4 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KFO99905.1 - 0.0004 19.9 0.1 0.84 9.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.1 KFO99905.1 - 0.0016 18.4 0.3 21 5.0 0.0 4.5 3 2 2 5 5 5 0 Thioredoxin AhpC-TSA PF00578.16 KFO99905.1 - 0.0016 18.0 1.6 1.5 8.5 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KFO99905.1 - 0.0038 16.7 2.6 1.5 8.3 0.1 2.8 3 0 0 3 3 3 2 Redoxin Mu-like_Com PF10122.4 KFO99905.1 - 0.43 9.6 8.2 2.9 7.0 0.9 3.4 3 0 0 3 3 3 0 Mu-like prophage protein Com TGF_beta PF00019.15 KFO99906.1 - 1.6e-44 150.4 1.7 3.5e-44 149.3 1.2 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFO99906.1 - 2.6e-40 138.2 0.6 3.1e-40 137.9 0.0 1.5 2 0 0 2 2 2 1 TGF-beta propeptide YafO_toxin PF13957.1 KFO99906.1 - 0.045 13.5 0.4 0.31 10.8 0.0 2.3 3 0 0 3 3 3 0 Toxin YafO, type II toxin-antitoxin system Plectin PF00681.15 KFO99907.1 - 3.6e-137 445.7 17.2 1.6e-18 65.9 0.2 16.4 14 3 3 17 17 17 13 Plectin repeat RIO1 PF01163.17 KFO99908.1 - 3.5e-76 254.7 0.5 3.5e-76 254.7 0.3 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KFO99908.1 - 0.00034 20.4 0.0 0.0056 16.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFO99908.1 - 0.0053 15.8 0.2 0.6 9.1 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family TRAP_alpha PF03896.11 KFO99909.1 - 4.7e-125 416.2 2.0 5.1e-125 416.1 1.4 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 KFO99909.1 - 0.38 8.6 3.5 0.42 8.4 2.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 KFO99909.1 - 3.9 7.4 8.0 6.3 6.8 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) E1_DerP2_DerF2 PF02221.10 KFO99911.1 - 3.1e-14 53.3 0.6 3.9e-14 53.0 0.4 1.2 1 0 0 1 1 1 1 ML domain Transglut_C PF00927.17 KFO99912.1 - 1.2e-41 141.0 0.3 3.1e-20 72.2 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 KFO99912.1 - 2.2e-36 124.4 0.0 1.9e-35 121.4 0.0 2.3 2 0 0 2 2 2 1 Transglutaminase family Transglut_core PF01841.14 KFO99912.1 - 1.4e-16 60.7 0.2 3.2e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF11 PF01345.13 KFO99912.1 - 0.1 12.6 0.7 17 5.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF11 NRN1 PF15056.1 KFO99914.1 - 6.5e-26 90.1 0.4 7.7e-26 89.8 0.3 1.1 1 0 0 1 1 1 1 Neuritin protein family tRNA-synt_2d PF01409.15 KFO99915.1 - 1.5e-49 168.4 1.9 7.4e-31 107.2 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KFO99915.1 - 1.9e-22 79.2 0.0 7.9e-22 77.2 0.0 2.1 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 KFO99915.1 - 0.0093 14.7 0.6 2.3 6.8 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) Complex1_LYR_1 PF13232.1 KFO99916.1 - 1.8e-11 44.0 1.5 2e-11 43.9 1.1 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFO99916.1 - 1.9e-11 43.5 1.8 2e-11 43.4 1.3 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) EntA_Immun PF08951.5 KFO99916.1 - 0.0063 16.6 0.7 0.007 16.4 0.5 1.0 1 0 0 1 1 1 1 Enterocin A Immunity cwf21 PF08312.7 KFO99916.1 - 0.039 13.8 0.5 0.046 13.5 0.3 1.1 1 0 0 1 1 1 0 cwf21 domain Ribonuc_P_40 PF08584.6 KFO99917.1 - 1.6e-96 322.6 0.0 1.9e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit ECH PF00378.15 KFO99918.1 - 1.6e-35 122.3 0.9 1.6e-35 122.3 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Chromo PF00385.19 KFO99918.1 - 1.1e-18 66.6 3.3 2.2e-18 65.6 2.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KFO99918.1 - 0.021 14.5 0.9 0.021 14.5 0.6 2.5 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain PWWP PF00855.12 KFO99918.1 - 0.11 12.7 1.0 0.47 10.6 0.5 2.2 2 0 0 2 2 2 0 PWWP domain ECH PF00378.15 KFO99919.1 - 3.2e-43 147.6 0.0 5.2e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ACBP PF00887.14 KFO99919.1 - 4.8e-31 106.2 0.4 1e-30 105.2 0.3 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein LamB_YcsF PF03746.11 KFO99919.1 - 0.0053 15.8 0.0 0.009 15.1 0.0 1.2 1 0 0 1 1 1 1 LamB/YcsF family TPR_21 PF09976.4 KFO99919.1 - 0.037 13.9 1.2 0.14 12.0 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KFO99920.1 - 5.4e-49 166.6 0.6 5.4e-49 166.6 0.4 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99920.1 - 1.1e-22 80.3 0.1 3.7e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFO99920.1 - 0.0022 16.8 0.5 0.0044 15.8 0.2 1.5 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase Sugar_tr PF00083.19 KFO99921.1 - 2e-22 79.4 18.8 3.1e-22 78.7 13.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFO99921.1 - 3e-17 62.3 22.0 3.6e-14 52.2 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KFO99921.1 - 0.027 12.5 2.7 0.062 11.4 1.8 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector Rieske PF00355.21 KFO99921.1 - 0.089 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain RepB-RCR_reg PF10723.4 KFO99922.1 - 0.062 13.0 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Replication regulatory protein RepB Tubulin PF00091.20 KFO99923.1 - 2.3e-32 112.5 0.0 2.7e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 KFO99923.1 - 3.7e-07 30.1 0.0 5.4e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KFO99925.1 - 3.2e-60 203.6 0.0 5e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFO99925.1 - 7.6e-51 171.4 0.1 1.2e-50 170.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFO99925.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Abhydrolase_6 PF12697.2 KFO99927.1 - 3.8e-34 118.5 0.0 4.5e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO99927.1 - 8.1e-23 81.1 0.0 6.1e-13 48.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFO99927.1 - 1.3e-18 67.1 0.0 3.8e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFO99927.1 - 9.2e-05 21.8 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KFO99927.1 - 0.00026 20.2 0.2 0.0034 16.6 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KFO99927.1 - 0.00059 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 KFO99927.1 - 0.00093 18.6 0.2 0.005 16.3 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KFO99927.1 - 0.0013 18.2 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 KFO99927.1 - 0.0048 16.7 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 KFO99927.1 - 0.0055 16.4 0.0 0.0093 15.6 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PhoPQ_related PF10142.4 KFO99927.1 - 0.035 12.6 0.0 0.056 11.9 0.0 1.3 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Esterase PF00756.15 KFO99927.1 - 0.043 13.2 0.3 0.22 10.9 0.1 2.1 2 1 1 3 3 3 0 Putative esterase LIP PF03583.9 KFO99927.1 - 0.085 12.0 0.0 3 6.9 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase KH_dom-like PF14714.1 KFO99927.1 - 0.1 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Pkinase PF00069.20 KFO99928.1 - 1.7e-53 181.4 0.0 2.8e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99928.1 - 1.1e-52 178.6 0.0 1.5e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.17 KFO99928.1 - 3.9e-19 68.2 2.0 1e-18 66.8 0.2 2.6 3 0 0 3 3 3 1 Death domain RHIM PF12721.2 KFO99928.1 - 5.9e-12 45.8 1.4 5.9e-12 45.8 1.0 2.7 3 0 0 3 3 3 1 RIP homotypic interaction motif Kinase-like PF14531.1 KFO99928.1 - 0.00037 19.5 0.0 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFO99928.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 KFO99928.1 - 0.09 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KFO99928.1 - 0.097 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFO99928.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Flavodoxin_2 PF02525.12 KFO99929.1 - 1.3e-51 174.9 0.0 1.5e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 KFO99929.1 - 8.5e-13 48.0 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 KFO99929.1 - 0.0056 16.0 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin DSPc PF00782.15 KFO99930.1 - 3e-27 94.8 0.5 8.2e-26 90.1 0.1 2.2 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFO99930.1 - 0.00041 19.7 0.4 0.00041 19.7 0.3 1.9 1 1 1 2 2 2 1 Protein-tyrosine phosphatase IRF-3 PF10401.4 KFO99931.1 - 6.8e-60 201.7 0.4 9.1e-60 201.2 0.3 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 KFO99931.1 - 4.4e-46 155.2 0.2 6.9e-46 154.5 0.1 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Sec5 PF15469.1 KFO99932.1 - 1.5e-56 190.9 1.2 5.2e-56 189.2 0.1 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 TIG PF01833.19 KFO99932.1 - 4.3e-08 33.0 0.4 9.3e-08 31.9 0.3 1.6 1 0 0 1 1 1 1 IPT/TIG domain SAM_2 PF07647.12 KFO99932.1 - 0.012 15.4 0.0 0.058 13.2 0.0 2.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4618 PF15397.1 KFO99932.1 - 0.15 11.3 5.9 1.2 8.4 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Epimerase PF01370.16 KFO99933.1 - 5.6e-64 215.8 0.0 7.8e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFO99933.1 - 6.8e-06 25.1 0.0 9.6e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase_Csub PF13950.1 KFO99933.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit MgsA_C PF12002.3 KFO99934.1 - 1.3e-59 200.6 0.0 7.1e-59 198.2 0.0 2.0 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KFO99934.1 - 2.2e-09 37.5 0.4 4.2e-09 36.6 0.3 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFO99934.1 - 1.4e-06 27.5 0.5 0.00039 19.5 0.1 2.2 1 1 1 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KFO99934.1 - 0.004 16.6 0.1 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 KFO99934.1 - 0.015 14.9 0.3 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.1 KFO99934.1 - 0.033 14.1 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Serpin PF00079.15 KFO99935.1 - 1.4e-133 445.6 3.7 1.6e-133 445.4 2.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFO99936.1 - 2.8e-41 141.8 1.6 3.1e-41 141.7 1.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Flu_B_NS1 PF02942.9 KFO99936.1 - 0.071 12.0 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) DUF677 PF05055.7 KFO99936.1 - 0.097 11.3 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Serpin PF00079.15 KFO99937.1 - 3.8e-116 388.2 3.5 4.3e-116 388.0 2.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFO99938.1 - 3.5e-132 441.0 9.8 3.9e-132 440.8 6.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) FbpA PF05833.6 KFO99938.1 - 0.015 13.8 0.4 0.025 13.1 0.3 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Serpin PF00079.15 KFO99939.1 - 2e-129 431.9 9.8 2.2e-129 431.8 6.8 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFO99940.1 - 5.1e-130 433.9 2.7 5.7e-130 433.7 1.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFO99941.1 - 1.8e-75 254.3 0.0 2e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) ThylakoidFormat PF11264.3 KFO99941.1 - 0.023 14.3 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Thylakoid formation protein N36 PF11438.3 KFO99941.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) Serpin PF00079.15 KFO99942.1 - 3.6e-77 260.0 0.2 4e-77 259.8 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFO99943.1 - 2.5e-127 425.0 2.1 2.8e-127 424.8 1.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFO99944.1 - 2.7e-100 336.1 8.0 3e-100 335.9 5.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AAA PF00004.24 KFO99945.1 - 1.1e-31 109.7 0.0 1.4e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFO99945.1 - 3.8e-07 30.3 0.1 8.6e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFO99945.1 - 1.1e-06 28.1 0.2 0.024 14.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFO99945.1 - 2e-06 27.3 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFO99945.1 - 2.4e-06 26.5 0.0 3.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KFO99945.1 - 4.9e-06 27.3 0.0 7.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFO99945.1 - 6.2e-06 26.1 0.0 8.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFO99945.1 - 1.2e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFO99945.1 - 1.2e-05 24.5 0.0 1.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFO99945.1 - 1.9e-05 24.7 0.0 0.00035 20.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KFO99945.1 - 0.00013 20.9 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KFO99945.1 - 0.00019 21.3 0.0 0.00026 20.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFO99945.1 - 0.00019 21.3 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KFO99945.1 - 0.00055 20.2 0.0 0.00087 19.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KFO99945.1 - 0.00097 18.8 0.0 0.037 13.7 0.0 2.1 1 1 0 1 1 1 1 NACHT domain KaiC PF06745.8 KFO99945.1 - 0.0011 18.1 0.1 0.47 9.5 0.0 2.1 1 1 1 2 2 2 2 KaiC RNA_helicase PF00910.17 KFO99945.1 - 0.002 18.2 0.0 0.003 17.7 0.0 1.3 1 1 0 1 1 1 1 RNA helicase ResIII PF04851.10 KFO99945.1 - 0.0026 17.6 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 KFO99945.1 - 0.0027 16.8 0.1 0.035 13.2 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin PhoH PF02562.11 KFO99945.1 - 0.0037 16.5 0.0 0.0085 15.3 0.0 1.6 2 0 0 2 2 1 1 PhoH-like protein Arch_ATPase PF01637.13 KFO99945.1 - 0.0038 16.9 0.0 0.23 11.1 0.0 2.0 1 1 1 2 2 2 1 Archaeal ATPase Mg_chelatase PF01078.16 KFO99945.1 - 0.0049 16.0 0.1 0.011 14.9 0.0 1.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KFO99945.1 - 0.0085 15.5 0.0 0.042 13.3 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFO99945.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KFO99945.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 KFO99945.1 - 0.014 14.4 0.1 0.96 8.3 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_21 PF13304.1 KFO99945.1 - 0.015 15.2 1.0 1.8 8.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 KFO99945.1 - 0.018 13.8 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Guanylate_kin PF00625.16 KFO99945.1 - 0.019 14.4 0.0 0.054 12.9 0.0 1.7 1 1 0 2 2 2 0 Guanylate kinase MCM PF00493.18 KFO99945.1 - 0.022 13.5 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_28 PF13521.1 KFO99945.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFO99945.1 - 0.037 13.7 0.0 3.2 7.4 0.0 2.1 2 0 0 2 2 2 0 NTPase Torsin PF06309.6 KFO99945.1 - 0.04 13.7 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_24 PF13479.1 KFO99945.1 - 0.048 13.2 0.1 0.071 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFO99945.1 - 0.049 13.1 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 KFO99945.1 - 0.056 12.2 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KFO99945.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 KFO99945.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 KFO99945.1 - 0.1 11.7 0.1 0.24 10.5 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 KFO99945.1 - 0.11 11.9 0.1 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 KFO99945.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 KFO99946.1 - 1.3e-29 101.8 0.3 2.4e-29 101.0 0.2 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA PF00004.24 KFO99946.1 - 0.00014 22.0 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.20 KFO99947.1 - 5e-30 104.6 0.0 6.6e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFO99947.1 - 2.4e-13 50.1 0.0 3.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFO99947.1 - 2.6e-11 43.7 0.0 4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFO99947.1 - 0.0038 17.2 0.1 0.075 13.0 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFO99947.1 - 0.084 12.2 0.2 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Bcl-2 PF00452.14 KFO99948.1 - 5.5e-30 103.4 0.1 7.4e-30 103.0 0.1 1.2 1 0 0 1 1 1 1 Apoptosis regulator proteins, Bcl-2 family BH4 PF02180.12 KFO99948.1 - 3.5e-13 48.7 0.2 7.7e-13 47.6 0.1 1.6 1 0 0 1 1 1 1 Bcl-2 homology region 4 Bcl-2_3 PF15286.1 KFO99948.1 - 0.0029 18.0 0.0 0.0043 17.4 0.0 1.3 1 0 0 1 1 1 1 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like MARVEL PF01284.18 KFO99949.1 - 0.043 13.6 3.0 0.066 13.0 2.1 1.4 1 0 0 1 1 1 0 Membrane-associating domain LRR_4 PF12799.2 KFO99950.1 - 2.6e-36 122.6 44.7 6.8e-06 25.5 0.9 12.1 4 3 11 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFO99950.1 - 5.5e-36 122.1 54.0 3.5e-07 29.8 0.5 10.2 3 2 12 15 15 15 15 Leucine rich repeat PP2C PF00481.16 KFO99950.1 - 2.2e-33 115.7 0.0 3.9e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 KFO99950.1 - 4.6e-25 83.7 57.3 0.051 13.6 0.4 19.9 18 1 2 20 20 20 10 Leucine Rich Repeat LRR_7 PF13504.1 KFO99950.1 - 9.3e-06 25.0 60.8 1.4 9.4 0.3 17.5 20 0 0 20 20 20 3 Leucine rich repeat LRR_6 PF13516.1 KFO99950.1 - 0.00032 20.4 43.1 0.075 13.1 0.9 13.9 15 2 2 17 17 17 1 Leucine Rich repeat JmjC PF02373.17 KFO99950.1 - 0.32 11.2 3.1 0.88 9.8 2.1 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF775 PF05603.7 KFO99950.1 - 0.7 9.3 6.0 29 4.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) IncA PF04156.9 KFO99950.1 - 2.7 7.5 11.2 12 5.4 5.3 2.5 2 0 0 2 2 2 0 IncA protein zf-CCHC PF00098.18 KFO99951.1 - 1.6e-05 24.5 1.6 4.1e-05 23.2 1.1 1.8 1 0 0 1 1 1 1 Zinc knuckle TNFR_c6 PF00020.13 KFO99952.1 - 8.1e-09 35.4 37.5 3.2e-05 23.9 7.0 5.1 3 1 2 5 5 5 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFO99952.1 - 0.00066 19.2 1.9 0.00066 19.2 1.3 4.3 3 1 0 3 3 3 1 GCC2 and GCC3 HEAT PF02985.17 KFO99953.1 - 4e-15 54.4 2.7 0.0081 16.1 0.0 7.2 6 1 1 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KFO99953.1 - 6e-09 36.0 0.1 0.00096 19.3 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 KFO99953.1 - 0.00087 19.7 7.5 0.87 10.1 0.0 5.1 5 1 1 6 6 6 2 HEAT-like repeat DUF4140 PF13600.1 KFO99953.1 - 0.067 13.6 1.7 5.4 7.5 0.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nuc_H_symport PF03825.11 KFO99953.1 - 0.11 11.2 0.1 4.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Nucleoside H+ symporter DivIC PF04977.10 KFO99953.1 - 3.9 7.0 7.3 1.5 8.3 0.4 2.5 2 0 0 2 2 2 0 Septum formation initiator PigN PF04987.9 KFO99954.1 - 5.1e-130 434.0 45.3 7e-130 433.6 31.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KFO99954.1 - 1.5e-15 57.3 0.1 1.8e-14 53.8 0.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFO99954.1 - 1.3e-06 28.0 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KFO99954.1 - 0.00024 20.3 0.0 0.0004 19.6 0.0 1.4 1 0 0 1 1 1 1 Sulfatase TPR_7 PF13176.1 KFO99954.1 - 0.053 13.3 0.4 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KFO99954.1 - 0.055 13.6 0.1 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_5 PF14634.1 KFO99955.1 - 1e-07 31.5 11.3 1e-07 31.5 7.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFO99955.1 - 3.9e-07 29.6 12.7 7.4e-07 28.7 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFO99955.1 - 7.2e-06 25.5 10.3 1.8e-05 24.2 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFO99955.1 - 8.1e-06 25.5 13.1 8.1e-06 25.5 9.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFO99955.1 - 0.00022 21.1 13.2 0.00022 21.1 9.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFO99955.1 - 0.0006 19.6 11.8 0.0006 19.6 8.2 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFO99955.1 - 0.0014 18.2 9.3 0.0027 17.3 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFO99955.1 - 1.9 8.1 13.7 7.2 6.2 9.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TNF PF00229.13 KFO99956.1 - 7.8e-17 61.0 0.0 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Abhydrolase_5 PF12695.2 KFO99957.1 - 5.7e-23 81.2 0.0 7.7e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFO99957.1 - 1.4e-14 54.5 0.0 1.1e-13 51.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFO99957.1 - 3.1e-11 43.2 0.0 3e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 KFO99957.1 - 1.3e-08 33.7 0.0 7.9e-05 21.3 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KFO99957.1 - 1.9e-06 27.5 0.0 0.0023 17.3 0.0 2.8 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KFO99957.1 - 8.5e-05 22.2 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFO99957.1 - 0.0003 20.0 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KFO99957.1 - 0.00099 18.8 0.0 0.0067 16.1 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KFO99957.1 - 0.0017 17.8 0.0 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 KFO99957.1 - 0.0048 16.3 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 KFO99957.1 - 0.0064 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KFO99957.1 - 0.035 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.7 KFO99957.1 - 0.044 12.5 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.20 KFO99957.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 KFO99957.1 - 0.12 11.6 0.0 0.8 8.9 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family DNA_ligase_A_M PF01068.16 KFO99958.1 - 2.9e-52 176.9 0.1 5.1e-52 176.1 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFO99958.1 - 3.3e-44 150.7 0.1 7.4e-44 149.6 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_IV PF11411.3 KFO99958.1 - 4.3e-20 71.1 1.8 9.2e-20 70.0 1.3 1.6 1 0 0 1 1 1 1 DNA ligase IV DNA_ligase_A_C PF04679.10 KFO99958.1 - 2e-16 60.1 0.0 7.2e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KFO99958.1 - 1e-13 51.2 0.9 9.8e-09 35.2 0.0 3.2 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 KFO99958.1 - 0.00015 21.5 0.8 0.0014 18.3 0.6 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain Tox-REase-9 PF15650.1 KFO99958.1 - 0.009 16.1 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 9 DUF1395 PF07160.7 KFO99958.1 - 0.35 10.3 3.8 0.12 11.8 0.2 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1395) SEO_C PF14577.1 KFO99959.1 - 0.058 12.7 0.1 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Sieve element occlusion C-terminus ARGLU PF15346.1 KFO99962.1 - 4.7e-49 165.9 59.1 4.7e-49 165.9 41.0 2.8 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 Ephrin PF00812.12 KFO99963.1 - 1.2e-56 190.3 0.2 1.5e-55 186.6 0.0 2.0 2 0 0 2 2 2 1 Ephrin Shisa PF13908.1 KFO99963.1 - 0.00012 22.3 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 KFO99963.1 - 0.0041 16.8 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Profilin PF00235.14 KFO99963.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Profilin Podoplanin PF05808.6 KFO99963.1 - 0.017 14.6 0.4 0.026 14.0 0.1 1.4 1 1 0 1 1 1 0 Podoplanin EphA2_TM PF14575.1 KFO99963.1 - 0.055 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0560 PF10577.4 KFO99963.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Yae1_N PF09811.4 KFO99964.1 - 2.6e-20 71.6 64.2 1.5e+04 -24.9 44.5 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal mTERF PF02536.9 KFO99966.1 - 0.019 13.5 0.1 0.022 13.3 0.1 1.1 1 0 0 1 1 1 0 mTERF DUF4496 PF14908.1 KFO99966.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) SBF PF01758.11 KFO99968.1 - 1.2e-48 165.0 19.0 1.2e-48 165.0 13.2 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family Toxin_16 PF07945.6 KFO99968.1 - 1.1 8.9 6.2 0.8 9.4 0.9 2.3 2 0 0 2 2 2 0 Janus-atracotoxin DUF2208 PF09973.4 KFO99968.1 - 1.2 8.2 4.3 0.73 9.0 1.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Mem_trans PF03547.13 KFO99968.1 - 2.2 6.4 15.6 0.063 11.5 5.2 2.2 2 1 0 2 2 2 0 Membrane transport protein IncA PF04156.9 KFO99968.1 - 3.3 7.2 6.4 14 5.1 0.0 3.5 3 0 0 3 3 3 0 IncA protein Methyltransf_16 PF10294.4 KFO99969.1 - 7e-34 116.7 0.0 8.7e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFO99969.1 - 1.8e-07 31.0 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO99969.1 - 0.00021 21.8 0.0 0.00033 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFO99969.1 - 0.0015 17.6 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 KFO99969.1 - 0.065 13.7 0.1 0.15 12.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain XPG_N PF00752.12 KFO99970.1 - 8.5e-32 109.4 0.0 2.6e-31 107.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KFO99970.1 - 8e-24 83.5 0.0 3.5e-23 81.4 0.0 2.3 1 0 0 1 1 1 1 XPG I-region PRANC PF09372.5 KFO99970.1 - 0.018 14.9 1.6 0.031 14.2 0.2 2.0 2 0 0 2 2 2 0 PRANC domain Glyco_transf_90 PF05686.7 KFO99972.1 - 1.7e-112 375.9 1.2 2.3e-112 375.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.14 KFO99972.1 - 3.5e-07 30.7 0.0 6.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.1 KFO99972.1 - 1.4e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Abhydrolase_5 PF12695.2 KFO99973.1 - 3e-21 75.6 0.0 3.7e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFO99973.1 - 7.1e-08 32.6 0.5 0.00091 19.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 KFO99973.1 - 0.00028 20.2 0.0 0.0011 18.2 0.0 1.9 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.8 KFO99973.1 - 0.00084 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KFO99973.1 - 0.045 13.3 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.7 KFO99973.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_16 PF10294.4 KFO99974.1 - 1.9e-30 105.6 0.0 2.2e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFO99974.1 - 1.7e-07 31.0 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFO99974.1 - 4.4e-05 24.0 0.0 6.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFO99974.1 - 6.4e-05 22.2 0.0 8.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFO99974.1 - 0.026 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.7 KFO99974.1 - 0.054 12.3 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_12 PF08242.7 KFO99974.1 - 0.095 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KFO99974.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.7 KFO99974.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPPII PF12580.3 KFO99975.1 - 7.6e-92 305.9 0.0 2.3e-91 304.3 0.0 1.8 2 0 0 2 2 2 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.17 KFO99975.1 - 1.1e-73 247.8 1.3 1.6e-73 247.3 0.9 1.2 1 0 0 1 1 1 1 Subtilase family TPPII_N PF12583.3 KFO99975.1 - 6.7e-05 23.0 0.2 0.00014 22.0 0.1 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal DUF4399 PF14347.1 KFO99975.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) FGF PF00167.13 KFO99977.1 - 8.5e-43 145.0 0.0 1.1e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFO99977.1 - 0.017 15.2 0.0 0.045 13.8 0.0 1.6 2 0 0 2 2 2 0 Fascin domain CDtoxinA PF03498.9 KFO99977.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family EGF_2 PF07974.8 KFO99978.1 - 3.6e-40 135.7 210.4 5.8e-07 29.5 12.3 10.3 8 3 1 10 10 10 9 EGF-like domain hEGF PF12661.2 KFO99978.1 - 0.012 15.6 2.4 0.012 15.6 1.6 14.7 21 0 0 21 21 21 0 Human growth factor-like EGF EGF PF00008.22 KFO99978.1 - 0.022 14.6 9.6 0.022 14.6 6.7 11.8 9 2 1 11 11 11 0 EGF-like domain G8 PF10162.4 KFO99978.1 - 0.17 11.6 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 G8 domain Ion_trans PF00520.26 KFO99979.1 - 1e-105 351.3 79.5 5.9e-35 120.3 6.9 5.5 4 1 1 5 5 5 5 Ion transport protein PKD_channel PF08016.7 KFO99979.1 - 0.01 14.3 67.6 0.0026 16.2 4.9 8.2 7 2 1 8 8 8 4 Polycystin cation channel TPR_11 PF13414.1 KFO99980.1 - 1.2e-43 146.5 40.3 3.5e-12 45.8 0.5 5.6 1 1 6 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFO99980.1 - 5.4e-35 117.5 20.3 4.6e-05 22.8 0.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat DUF1736 PF08409.6 KFO99980.1 - 6.1e-33 112.2 2.4 1.3e-32 111.2 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.1 KFO99980.1 - 1.8e-29 99.4 21.5 6.8e-06 25.8 0.2 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFO99980.1 - 2.4e-29 98.8 17.7 6.6e-06 25.6 0.3 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFO99980.1 - 1.4e-27 95.4 15.6 5.4e-09 35.8 0.5 4.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFO99980.1 - 3.7e-26 91.1 20.4 2.4e-08 34.4 0.3 5.1 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFO99980.1 - 6.6e-22 75.6 13.2 8.4e-05 22.0 0.4 7.5 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 KFO99980.1 - 1.6e-19 68.5 10.6 0.001 19.5 0.1 8.3 2 1 7 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 KFO99980.1 - 6e-15 55.3 10.1 1.5e-05 25.1 1.0 5.2 2 1 4 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFO99980.1 - 6.7e-11 41.7 20.9 0.00095 19.0 0.3 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFO99980.1 - 2.1e-10 39.6 5.5 0.46 10.4 0.1 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.9 KFO99980.1 - 2.5e-05 24.2 0.2 1.1 9.8 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFO99980.1 - 5e-05 23.4 5.3 3.1 8.4 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KFO99980.1 - 0.0036 17.4 10.6 0.08 13.0 0.3 3.9 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFO99980.1 - 0.006 16.4 1.7 0.24 11.2 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 KFO99980.1 - 0.014 14.1 2.5 0.84 8.3 0.1 2.6 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 KFO99980.1 - 0.047 13.8 4.2 0.93 9.6 0.1 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat AIG2 PF06094.7 KFO99981.1 - 1.3e-19 70.6 0.1 1.6e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KFO99981.1 - 0.052 13.6 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family zf-C2H2 PF00096.21 KFO99983.1 - 9.1e-22 76.0 30.0 7.5e-06 25.9 0.1 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFO99983.1 - 1.8e-21 75.3 35.4 7.4e-09 35.4 0.2 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFO99983.1 - 7e-19 66.7 19.6 0.00079 19.5 0.1 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFO99983.1 - 1.6e-09 37.6 15.4 0.001 19.1 0.2 4.7 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFO99983.1 - 5.1e-05 23.3 14.4 0.0014 18.7 0.5 4.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFO99983.1 - 0.0036 17.1 7.5 0.8 9.7 0.0 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger HpcH_HpaI PF03328.9 KFO99984.1 - 1.7e-46 157.9 0.0 2.1e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KFO99984.1 - 8.7e-11 41.2 0.1 6.5e-07 28.4 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold 7tm_1 PF00001.16 KFO99985.1 - 1e-52 178.8 13.9 1.2e-52 178.6 9.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFO99985.1 - 9e-05 22.2 2.8 9e-05 22.2 1.9 2.9 2 1 1 3 3 3 1 Olfactory receptor DUF1049 PF06305.6 KFO99985.1 - 0.057 12.9 1.4 4.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF3357 PF11837.3 KFO99985.1 - 0.14 12.0 0.5 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) OapA_N PF08525.6 KFO99985.1 - 0.34 10.7 2.6 1 9.2 1.8 1.9 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif 7TM_GPCR_Srd PF10317.4 KFO99985.1 - 2.3 7.1 16.1 0.46 9.4 0.7 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd UBA PF00627.26 KFO99986.1 - 1.3e-12 47.1 0.4 1.3e-12 47.1 0.3 1.6 2 0 0 2 2 2 1 UBA/TS-N domain FeoA PF04023.9 KFO99986.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 FeoA domain 7tm_1 PF00001.16 KFO99987.1 - 1.1e-57 195.1 15.8 1.3e-57 194.8 10.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFO99987.1 - 0.0012 18.6 9.8 0.0012 18.6 6.8 3.0 2 1 2 4 4 4 1 Olfactory receptor 7tm_1 PF00001.16 KFO99988.1 - 2.9e-35 121.6 24.4 3.7e-35 121.3 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ded_cyto PF06920.8 KFO99989.1 - 1.2e-66 223.3 1.5 5.6e-66 221.2 1.0 2.3 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFO99989.1 - 3.4e-57 193.0 1.0 9.8e-57 191.5 0.4 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 KFO99989.1 - 2.1e-30 104.4 0.3 5.8e-30 103.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.24 KFO99989.1 - 1.3e-12 47.8 0.2 7.4e-12 45.3 0.1 2.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFO99989.1 - 2.8e-05 24.2 0.0 0.00016 21.8 0.0 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFO99989.1 - 0.022 14.8 0.1 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.1 KFO99989.1 - 0.46 10.7 4.1 0.47 10.7 0.1 3.1 3 1 0 3 3 3 0 Pleckstrin homology domain PTR2 PF00854.16 KFO99990.1 - 1.4e-122 409.1 11.9 7.4e-117 390.2 5.1 2.2 2 0 0 2 2 2 2 POT family DUF843 PF05814.6 KFO99990.1 - 0.0028 17.4 0.2 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 Baculovirus protein of unknown function (DUF843) Neurensin PF14927.1 KFO99990.1 - 0.036 13.4 0.0 0.6 9.4 0.0 2.6 2 0 0 2 2 2 0 Neurensin Pkinase PF00069.20 KFO99991.1 - 1.4e-72 244.0 0.0 1.8e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFO99991.1 - 4.4e-54 183.2 0.0 5.8e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFO99991.1 - 0.00048 19.1 0.0 0.0018 17.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 KFO99991.1 - 0.00057 19.1 0.0 0.0017 17.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) APH PF01636.18 KFO99991.1 - 0.021 14.5 0.0 3.4 7.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KFO99991.1 - 0.069 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4288 PF14119.1 KFO99991.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) RhoGEF PF00621.15 KFO99992.1 - 7.7e-31 107.3 1.7 7.7e-31 107.3 1.2 1.9 2 0 0 2 2 2 1 RhoGEF domain FERM_C PF09380.5 KFO99992.1 - 2.4e-25 88.5 0.4 5.7e-25 87.3 0.3 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain PH PF00169.24 KFO99992.1 - 4.7e-24 84.5 0.5 4.9e-15 55.6 0.6 2.8 2 0 0 2 2 2 2 PH domain FA PF08736.6 KFO99992.1 - 3.2e-16 58.8 2.6 1.2e-15 56.9 1.8 2.1 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.13 KFO99992.1 - 1.4e-13 51.1 1.1 1.4e-13 51.1 0.8 2.9 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.5 KFO99992.1 - 1.4e-13 50.6 0.1 4.7e-13 49.0 0.1 2.0 1 0 0 1 1 1 1 FERM N-terminal domain PH_2 PF08458.5 KFO99992.1 - 0.075 12.9 0.0 14 5.6 0.0 2.8 2 0 0 2 2 2 0 Plant pleckstrin homology-like region HEAT_2 PF13646.1 KFO99993.1 - 4.1e-21 75.0 1.1 1.2e-11 44.6 0.0 6.7 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KFO99993.1 - 3.5e-19 67.1 13.4 9.2e-06 25.3 0.0 9.3 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 KFO99993.1 - 3.6e-18 65.4 1.0 9e-07 29.2 0.0 8.0 8 0 0 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFO99993.1 - 5.6e-13 49.0 7.7 1.6e-06 28.4 0.0 8.4 6 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KFO99993.1 - 0.0003 20.6 0.1 0.0057 16.5 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 KFO99993.1 - 0.00064 19.4 1.4 12 5.8 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KFO99993.1 - 1.4 9.6 5.3 28 5.5 0.0 4.5 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat TRADD_N PF09034.5 KFO99994.1 - 1.4e-40 137.7 2.6 2.4e-40 136.9 1.8 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain Death PF00531.17 KFO99994.1 - 2.4e-09 36.8 0.9 5.5e-09 35.6 0.1 1.9 2 0 0 2 2 2 1 Death domain UPF0183 PF03676.9 KFO99995.1 - 6.1e-180 597.9 0.6 7.1e-180 597.7 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) CBF_beta PF02312.12 KFO99996.1 - 1.2e-46 158.4 0.1 1.3e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Core binding factor beta subunit G-alpha PF00503.15 KFO99997.1 - 4.5e-116 387.7 4.0 5e-116 387.5 2.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFO99997.1 - 2.9e-13 49.4 0.0 6.9e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFO99998.1 - 2.9e-39 134.8 4.9 3.2e-39 134.7 3.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit zf-TRM13_CCCH PF11722.3 KFO99998.1 - 0.067 12.5 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein zf-RING_2 PF13639.1 KFO99999.1 - 5.3e-15 54.9 8.8 7.6e-15 54.4 4.4 2.3 2 0 0 2 2 2 1 Ring finger domain CUE PF02845.11 KFO99999.1 - 1.3e-10 40.5 0.1 2.7e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 CUE domain zf-C3HC4_3 PF13920.1 KFO99999.1 - 1.3e-09 37.5 3.3 3.1e-09 36.3 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFO99999.1 - 5.1e-09 36.0 5.7 1.5e-08 34.5 4.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFO99999.1 - 3.7e-08 32.9 5.2 7.3e-08 31.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFO99999.1 - 4.3e-08 33.1 8.2 3e-07 30.4 5.0 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFO99999.1 - 2.9e-06 26.9 3.8 6.1e-06 25.8 2.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFO99999.1 - 9.3e-05 22.1 2.3 0.00032 20.4 1.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFO99999.1 - 0.0011 18.8 4.4 0.0021 17.8 3.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFO99999.1 - 0.0019 17.8 4.5 0.0059 16.2 3.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger MRAP PF15183.1 KFO99999.1 - 0.03 13.9 0.4 0.095 12.3 0.3 1.8 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family RINGv PF12906.2 KFO99999.1 - 0.24 11.4 7.7 0.56 10.2 5.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 KFO99999.1 - 0.33 10.5 2.4 1 9.0 1.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFO99999.1 - 0.4 10.6 5.6 1.2 9.1 3.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain NUDIX_2 PF13869.1 KFP00001.1 - 1.1e-74 249.9 0.1 2.4e-74 248.7 0.0 1.5 1 1 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 KFP00001.1 - 0.0086 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ofd1_CTDD PF10637.4 KFP00002.1 - 2.2e-51 174.5 0.1 4.7e-45 153.8 0.1 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KFP00002.1 - 2.3e-14 53.7 0.3 1.2e-12 48.2 0.0 2.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BBS2_C PF14782.1 KFP00003.1 - 4e-171 569.3 0.0 3.1e-169 563.1 0.0 2.2 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.1 KFP00003.1 - 4.5e-48 161.6 0.0 4.2e-46 155.2 0.0 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.1 KFP00003.1 - 7.2e-43 145.4 0.1 2e-42 144.0 0.0 1.8 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.18 KFP00003.1 - 2.3e-06 27.0 0.0 0.0003 20.3 0.0 2.6 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.1 KFP00003.1 - 1.5e-05 25.2 2.0 0.024 15.0 0.4 3.4 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Metallothio PF00131.15 KFP00004.1 - 8.6e-12 44.7 59.2 9.4e-12 44.6 41.0 1.0 1 0 0 1 1 1 1 Metallothionein Metallothio PF00131.15 KFP00005.1 - 7.1e-12 45.0 63.7 7.6e-12 44.9 44.2 1.0 1 0 0 1 1 1 1 Metallothionein Nic96 PF04097.9 KFP00006.1 - 1.9e-197 657.1 0.3 2.3e-197 656.9 0.2 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Apc3 PF12895.2 KFP00006.1 - 0.74 9.9 6.2 0.56 10.3 0.4 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AA_permease PF00324.16 KFP00007.1 - 2.6e-134 448.1 35.4 3.1e-134 447.9 24.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.5 KFP00007.1 - 1.7e-15 56.0 0.0 3.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid permease N-terminal Tmemb_170 PF10190.4 KFP00008.1 - 3.8e-45 152.2 5.2 4.2e-45 152.1 3.6 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF2516 PF10724.4 KFP00008.1 - 0.08 12.9 1.7 0.085 12.8 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) CytB6-F_Fe-S PF08802.5 KFP00008.1 - 5.8 6.9 8.6 24 5.0 1.3 3.1 2 1 1 3 3 3 0 Cytochrome B6-F complex Fe-S subunit BCNT PF07572.7 KFP00009.1 - 1e-28 99.0 0.7 1e-28 99.0 0.5 2.3 2 0 0 2 2 2 1 Bucentaur or craniofacial development ALS2CR8 PF15299.1 KFP00009.1 - 0.015 14.8 2.1 0.022 14.3 1.4 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Trypsin PF00089.21 KFP00010.1 - 3.5e-50 170.6 0.1 3.8e-50 170.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP00010.1 - 0.0029 16.9 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 KFP00010.1 - 0.052 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Trypsin PF00089.21 KFP00011.1 - 0.014 14.9 0.1 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 Trypsin C1q PF00386.16 KFP00012.1 - 6.5e-18 64.9 0.0 7.1e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 KFP00012.1 - 0.039 13.5 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family LRR_4 PF12799.2 KFP00013.1 - 3.9e-28 96.5 35.3 1.7e-09 37.0 1.6 4.5 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP00013.1 - 1.4e-20 72.7 26.2 3.2e-09 36.3 1.7 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KFP00013.1 - 3.8e-19 65.7 18.0 0.0073 16.1 0.1 6.4 6 0 0 6 6 6 6 Leucine Rich Repeat LRR_7 PF13504.1 KFP00013.1 - 5.4e-11 40.8 16.4 1 9.8 0.0 6.9 7 0 0 7 7 7 5 Leucine rich repeat LRR_6 PF13516.1 KFP00013.1 - 1e-07 31.2 16.4 1.3 9.3 0.1 6.4 6 0 0 6 6 6 4 Leucine Rich repeat CheY-binding PF09078.6 KFP00013.1 - 0.15 12.1 0.3 0.75 9.8 0.1 2.1 1 1 1 2 2 2 0 CheY binding DNA_methylase PF00145.12 KFP00014.1 - 2.5e-29 102.4 0.0 3.6e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Filament PF00038.16 KFP00015.1 - 2.7e-116 388.4 50.7 3.2e-116 388.1 35.1 1.1 1 0 0 1 1 1 1 Intermediate filament protein Filament_head PF04732.9 KFP00015.1 - 2.7e-11 44.0 0.2 7.4e-11 42.6 0.1 1.8 2 0 0 2 2 1 1 Intermediate filament head (DNA binding) region Reo_sigmaC PF04582.7 KFP00015.1 - 6.5e-05 22.2 6.1 0.0053 15.9 0.3 2.5 1 1 0 2 2 2 2 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KFP00015.1 - 0.00016 19.5 20.8 0.00016 19.5 14.4 2.8 1 1 2 3 3 3 2 Myosin tail TPR_MLP1_2 PF07926.7 KFP00015.1 - 0.00025 20.7 49.9 0.0059 16.3 1.3 4.6 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 KFP00015.1 - 0.00078 19.2 1.2 0.00078 19.2 0.8 4.0 2 1 1 4 4 4 1 Protein of unknown function (DUF1664) DUF4515 PF14988.1 KFP00015.1 - 0.0045 16.6 44.3 0.021 14.5 21.6 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4515) HR1 PF02185.11 KFP00015.1 - 0.011 15.4 13.2 0.011 15.4 9.1 5.0 4 3 1 5 5 5 0 Hr1 repeat HALZ PF02183.13 KFP00015.1 - 0.016 14.9 2.8 0.016 14.9 1.9 6.8 6 3 1 7 7 6 0 Homeobox associated leucine zipper DUF573 PF04504.9 KFP00015.1 - 0.13 12.5 6.5 3.4 7.9 0.1 3.5 2 2 0 3 3 2 0 Protein of unknown function, DUF573 Laminin_II PF06009.7 KFP00015.1 - 0.14 11.8 27.0 1.6 8.4 1.1 3.6 1 1 1 3 3 3 0 Laminin Domain II IncA PF04156.9 KFP00015.1 - 0.14 11.6 52.8 1.4 8.4 11.1 3.7 1 1 2 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 KFP00015.1 - 0.15 11.9 19.2 0.41 10.4 1.3 4.5 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4266 PF14086.1 KFP00015.1 - 0.23 11.9 0.6 0.94 10.0 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Exotox-A_target PF09102.5 KFP00015.1 - 0.24 10.8 2.4 0.24 10.8 0.3 1.9 2 0 0 2 2 2 0 Exotoxin A, targeting DUF3584 PF12128.3 KFP00015.1 - 0.46 7.7 41.0 1.8 5.7 28.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF869 PF05911.6 KFP00015.1 - 0.55 8.3 35.3 0.14 10.3 12.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF948 PF06103.6 KFP00015.1 - 0.56 10.1 12.5 3 7.7 0.5 4.7 2 2 4 6 6 6 0 Bacterial protein of unknown function (DUF948) WEMBL PF05701.6 KFP00015.1 - 0.73 8.2 40.3 0.31 9.4 12.8 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Atg14 PF10186.4 KFP00015.1 - 0.96 8.3 35.9 0.61 8.9 12.3 2.2 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 KFP00015.1 - 1.3 8.8 44.8 0.036 13.9 6.1 3.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 KFP00015.1 - 1.4 9.0 27.9 1.6 8.8 6.2 3.9 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family WXG100 PF06013.7 KFP00015.1 - 1.6 8.8 19.4 3.8 7.5 0.1 4.9 2 2 0 4 4 4 0 Proteins of 100 residues with WXG GAS PF13851.1 KFP00015.1 - 1.7 7.8 46.1 0.0076 15.4 9.1 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.4 KFP00015.1 - 1.7 8.6 43.8 0.034 14.1 6.3 3.9 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.16 KFP00015.1 - 2.7 8.0 30.6 2 8.4 0.3 6.0 4 1 1 5 5 5 0 bZIP transcription factor CCDC92 PF14916.1 KFP00015.1 - 2.7 7.6 20.5 0.12 11.9 4.0 4.8 4 2 1 5 5 5 0 Coiled-coil domain of unknown function ERM PF00769.14 KFP00015.1 - 2.9 7.3 49.0 0.13 11.7 11.4 3.2 1 1 1 2 2 1 0 Ezrin/radixin/moesin family DUF4140 PF13600.1 KFP00015.1 - 3.5 8.1 32.0 2 8.8 0.7 5.5 2 1 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.7 KFP00015.1 - 4.1 7.6 34.6 0.46 10.6 3.4 4.3 2 1 2 4 4 4 0 Centromere protein H (CENP-H) HGTP_anticodon PF03129.15 KFP00015.1 - 4.8 7.1 10.7 3.9 7.4 0.1 3.7 4 0 0 4 4 3 0 Anticodon binding domain ATG16 PF08614.6 KFP00015.1 - 6 6.6 41.6 30 4.3 13.4 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Glyco_transf_29 PF00777.13 KFP00016.1 - 1.6e-76 257.0 0.0 2.4e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF2636 PF11120.3 KFP00016.1 - 0.033 13.6 0.2 0.069 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) PTPLA PF04387.9 KFP00017.1 - 2.4e-59 199.4 14.1 2.8e-59 199.2 9.8 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA VHS PF00790.14 KFP00018.1 - 3.6e-44 149.8 1.7 4.7e-44 149.4 0.1 1.9 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 KFP00018.1 - 3e-16 58.5 0.1 5.7e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP00018.1 - 2.6e-13 49.3 0.0 4.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP00018.1 - 2.4e-12 46.1 0.0 4.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KFP00018.1 - 0.00021 20.6 0.6 0.00063 19.1 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif HEAT_2 PF13646.1 KFP00018.1 - 0.066 13.4 0.1 0.59 10.4 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.17 KFP00018.1 - 0.21 11.7 1.1 0.76 10.0 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat Lectin_C PF00059.16 KFP00019.1 - 5.6e-73 242.2 12.4 5.8e-24 84.7 0.2 5.3 5 0 0 5 5 5 4 Lectin C-type domain fn2 PF00040.14 KFP00019.1 - 2.3e-14 53.1 8.4 2.3e-14 53.1 5.8 2.7 2 1 1 3 3 3 1 Fibronectin type II domain Herpes_UL45 PF05473.7 KFP00019.1 - 3.1e-10 39.8 0.2 2.5e-06 27.0 0.0 3.5 3 0 0 3 3 3 2 UL45 protein Ricin_B_lectin PF00652.17 KFP00019.1 - 1.7e-08 34.5 0.3 4.7e-08 33.1 0.2 1.8 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Chordopox_A33R PF05966.7 KFP00019.1 - 1.1e-05 24.3 3.3 0.00093 18.0 0.0 3.6 4 0 0 4 4 4 1 Chordopoxvirus A33R protein Xlink PF00193.12 KFP00019.1 - 0.00043 20.3 0.3 6.8 6.8 0.1 4.4 4 1 0 4 4 4 2 Extracellular link domain RicinB_lectin_2 PF14200.1 KFP00019.1 - 0.019 15.3 0.1 0.067 13.5 0.0 2.0 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Lectin_C PF00059.16 KFP00020.1 - 8.1e-152 495.6 53.1 1.8e-21 76.7 0.5 9.3 9 0 0 9 9 9 8 Lectin C-type domain Herpes_UL45 PF05473.7 KFP00020.1 - 3.6e-15 55.9 8.0 0.0013 18.2 0.1 6.2 5 1 1 6 6 6 4 UL45 protein fn2 PF00040.14 KFP00020.1 - 1.5e-12 47.2 3.0 1.5e-12 47.2 2.1 2.6 2 0 0 2 2 2 1 Fibronectin type II domain Xlink PF00193.12 KFP00020.1 - 1.5e-10 40.9 6.8 0.94 9.6 0.0 7.7 8 1 0 8 8 8 4 Extracellular link domain Ricin_B_lectin PF00652.17 KFP00020.1 - 2.6e-07 30.7 2.6 8.6e-07 29.0 1.8 2.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Chordopox_A33R PF05966.7 KFP00020.1 - 4.5e-05 22.3 21.0 0.053 12.3 0.1 6.8 7 1 0 7 7 7 4 Chordopoxvirus A33R protein Lectin_C PF00059.16 KFP00021.1 - 4.8e-72 239.3 8.4 8.6e-24 84.1 0.8 4.9 4 0 0 4 4 4 4 Lectin C-type domain fn2 PF00040.14 KFP00021.1 - 1.4e-17 63.3 8.7 1.4e-17 63.3 6.0 2.4 2 0 0 2 2 2 1 Fibronectin type II domain Ricin_B_lectin PF00652.17 KFP00021.1 - 8.3e-10 38.7 0.5 8.3e-10 38.7 0.3 2.3 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain Herpes_UL45 PF05473.7 KFP00021.1 - 8.4e-08 31.8 3.7 2e-05 24.1 0.0 3.9 4 1 1 5 5 5 1 UL45 protein Chordopox_A33R PF05966.7 KFP00021.1 - 1.3e-05 24.0 3.5 0.036 12.8 0.0 3.5 3 0 0 3 3 3 2 Chordopoxvirus A33R protein Xlink PF00193.12 KFP00021.1 - 0.0067 16.4 7.7 1.1 9.3 0.1 5.2 4 2 2 6 6 6 1 Extracellular link domain RicinB_lectin_2 PF14200.1 KFP00021.1 - 0.054 13.8 2.8 0.086 13.2 0.0 2.7 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Lectin_C PF00059.16 KFP00022.1 - 1.9e-72 240.5 10.3 2e-19 70.1 0.4 4.3 4 0 0 4 4 4 4 Lectin C-type domain fn2 PF00040.14 KFP00022.1 - 1.5e-18 66.5 5.9 4.9e-18 64.8 4.1 2.0 1 0 0 1 1 1 1 Fibronectin type II domain Herpes_UL45 PF05473.7 KFP00022.1 - 1.3e-08 34.4 0.4 0.0028 17.0 0.0 3.5 2 1 1 3 3 3 3 UL45 protein Chordopox_A33R PF05966.7 KFP00022.1 - 6.4e-07 28.3 5.5 0.0032 16.2 0.2 3.9 4 0 0 4 4 4 2 Chordopoxvirus A33R protein Xlink PF00193.12 KFP00022.1 - 1.5e-05 24.9 5.6 3.2 7.9 0.0 5.6 5 0 0 5 5 5 2 Extracellular link domain MBT PF02820.13 KFP00022.1 - 0.0039 17.0 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 mbt repeat Lectin_C PF00059.16 KFP00023.1 - 1.8e-17 63.8 0.2 3.4e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Lectin C-type domain MFS_Mycoplasma PF07672.8 KFP00023.1 - 0.0051 16.0 0.7 0.0074 15.4 0.5 1.2 1 0 0 1 1 1 1 Mycoplasma MFS transporter DUF4366 PF14283.1 KFP00023.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PLDc_N PF13396.1 KFP00023.1 - 0.031 13.9 1.5 0.056 13.1 1.0 1.5 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF2621 PF11084.3 KFP00023.1 - 0.07 12.8 0.4 0.16 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) DUF3139 PF11337.3 KFP00023.1 - 0.11 12.7 7.1 0.83 9.9 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) Spore_YhaL PF14147.1 KFP00023.1 - 0.3 10.5 1.3 0.89 9.0 0.6 2.0 2 0 0 2 2 2 0 Sporulation protein YhaL Zip PF02535.17 KFP00024.1 - 5.3e-59 199.8 9.9 1e-58 198.8 6.9 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Guanylate_kin PF00625.16 KFP00025.1 - 1.7e-49 167.7 1.1 2.1e-49 167.4 0.1 1.7 2 0 0 2 2 2 1 Guanylate kinase VGCC_beta4Aa_N PF12052.3 KFP00025.1 - 6e-24 83.6 7.8 6e-24 83.6 5.4 2.6 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal SH3_1 PF00018.23 KFP00025.1 - 9.7e-05 21.6 0.1 0.00034 19.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain ImpA-rel_N PF06812.7 KFP00025.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 ImpA-related N-terminal SH3_9 PF14604.1 KFP00025.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Nol1_Nop2_Fmu PF01189.12 KFP00026.1 - 1.4e-39 136.1 0.0 3.1e-39 135.0 0.0 1.5 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KFP00026.1 - 1e-08 34.8 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFP00026.1 - 5.4e-08 33.0 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KFP00026.1 - 1.9e-07 31.1 0.0 3.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP00026.1 - 2.8e-07 31.0 0.0 5.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PUA PF01472.15 KFP00026.1 - 0.00018 21.1 0.0 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 PUA domain PCMT PF01135.14 KFP00026.1 - 0.0019 17.8 0.0 0.0044 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 KFP00026.1 - 0.0033 17.0 0.0 0.0069 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.7 KFP00026.1 - 0.012 16.1 0.0 0.11 12.9 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFP00026.1 - 0.034 13.5 0.1 0.32 10.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 KFP00026.1 - 0.045 12.8 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Arf PF00025.16 KFP00027.1 - 6.5e-65 217.6 0.1 7.1e-65 217.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP00027.1 - 3.1e-14 52.6 0.0 3.5e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP00027.1 - 6.2e-13 48.3 0.0 7.4e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFP00027.1 - 4e-11 43.4 0.0 5.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KFP00027.1 - 1e-08 34.2 0.4 3.1e-06 26.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFP00027.1 - 4.3e-08 32.5 0.1 5e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP00027.1 - 9e-08 32.0 0.1 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP00027.1 - 0.00033 20.1 0.0 0.0059 16.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFP00027.1 - 0.0036 17.1 0.1 0.014 15.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 KFP00027.1 - 0.085 11.9 0.3 0.26 10.3 0.1 1.8 1 1 1 2 2 2 0 KaiC FeoB_N PF02421.13 KFP00027.1 - 0.11 11.8 0.5 0.38 10.0 0.2 1.8 1 1 1 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KFP00027.1 - 0.15 11.9 0.1 1.5 8.6 0.0 1.9 1 1 1 2 2 2 0 Dynamin family Yae1_N PF09811.4 KFP00028.1 - 1e-19 69.7 61.7 1.5e+04 -22.3 42.8 5.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Yae1_N PF09811.4 KFP00029.1 - 5.2e-19 67.4 60.1 1.5e+04 -20.9 41.7 5.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MAM PF00629.18 KFP00030.1 - 5.2e-18 65.3 1.3 5.8e-18 65.1 0.9 1.0 1 0 0 1 1 1 1 MAM domain MAM PF00629.18 KFP00031.1 - 3.3e-41 140.7 0.0 3.7e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 MAM domain MAM PF00629.18 KFP00032.1 - 7.9e-24 84.2 2.0 8.9e-24 84.0 1.4 1.0 1 0 0 1 1 1 1 MAM domain Aconitase PF00330.15 KFP00033.1 - 0.061 11.7 0.0 0.076 11.4 0.0 1.0 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) PSI PF01437.20 KFP00034.1 - 2.4e-07 30.7 11.0 4.1e-07 30.0 7.6 1.3 1 0 0 1 1 1 1 Plexin repeat Nebulin PF00880.13 KFP00035.1 - 1.1e-28 97.4 2.8 2.5e-10 39.4 0.1 3.6 3 0 0 3 3 3 3 Nebulin repeat SH3_9 PF14604.1 KFP00035.1 - 2.4e-16 59.0 0.0 3.8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP00035.1 - 1.3e-13 50.1 0.0 2.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LIM PF00412.17 KFP00035.1 - 2.5e-07 30.6 6.6 5.2e-07 29.6 4.6 1.6 1 0 0 1 1 1 1 LIM domain SH3_2 PF07653.12 KFP00035.1 - 4.4e-06 26.1 0.0 9.8e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4584 PF15223.1 KFP00036.1 - 5.8e-93 312.2 11.4 9.3e-93 311.6 7.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4584) Ski_Sno PF02437.12 KFP00036.1 - 6.8e-17 61.0 0.1 1.4e-16 60.0 0.1 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family zf-HC5HC2H_2 PF13832.1 KFP00037.1 - 3.3e-31 107.5 20.6 3.9e-31 107.2 7.9 2.5 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFP00037.1 - 1.8e-20 72.8 10.5 1.8e-20 72.8 7.3 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KFP00037.1 - 6.4e-13 47.7 4.4 6.4e-13 47.7 3.0 2.8 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 KFP00037.1 - 4.7e-07 29.3 9.9 4.7e-07 29.3 6.9 2.9 2 0 0 2 2 2 2 PHD-finger HCaRG PF07258.9 KFP00038.1 - 7.8e-15 54.8 0.0 9e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 HCaRG protein Lip_prot_lig_C PF10437.4 KFP00038.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus DUF3789 PF12664.2 KFP00038.1 - 0.12 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Cys_rich_FGFR PF00839.12 KFP00038.1 - 0.41 10.6 3.3 2.7 7.9 0.7 2.2 1 1 1 2 2 2 0 Cysteine rich repeat zf-RING_2 PF13639.1 KFP00039.1 - 0.034 13.9 2.1 0.067 13.0 1.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KFP00039.1 - 0.04 13.9 4.8 0.088 12.8 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4467 PF14729.1 KFP00039.1 - 0.04 14.2 0.1 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) zf-C3HC4_3 PF13920.1 KFP00039.1 - 0.078 12.6 2.7 0.14 11.8 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP00039.1 - 0.58 9.8 4.9 1.3 8.7 3.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arm PF00514.18 KFP00040.1 - 4.1e-42 140.6 19.5 7.2e-09 35.1 0.0 9.1 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP00040.1 - 4e-20 71.8 11.2 8.8e-06 25.9 0.6 5.2 2 2 4 6 6 6 6 HEAT repeats HEAT PF02985.17 KFP00040.1 - 1.1e-19 68.7 10.7 0.012 15.6 0.1 8.5 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 KFP00040.1 - 1.6e-17 63.3 11.3 1.4e-05 25.3 0.0 6.6 3 1 4 7 7 7 5 HEAT-like repeat Adaptin_N PF01602.15 KFP00040.1 - 7.5e-09 34.4 4.3 0.023 13.0 1.1 3.7 2 1 1 3 3 3 3 Adaptin N terminal region DNA_alkylation PF08713.6 KFP00040.1 - 1.2e-08 34.7 0.0 0.47 9.9 0.0 4.3 2 1 2 4 4 4 3 DNA alkylation repair enzyme Proteasom_PSMB PF10508.4 KFP00040.1 - 2.8e-08 32.4 2.3 0.00014 20.2 0.2 3.5 1 1 2 4 4 4 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KFP00040.1 - 1.4e-07 31.5 0.5 0.22 11.3 0.1 4.6 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFP00040.1 - 7e-05 22.2 0.1 0.13 11.5 0.0 3.7 3 1 0 3 3 3 1 CLASP N terminal HEAT_PBS PF03130.11 KFP00040.1 - 8.8e-05 22.6 9.3 0.18 12.3 0.2 5.9 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 KFP00040.1 - 0.0012 18.5 0.1 4.5 7.0 0.0 3.7 4 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain XPC-binding PF09280.6 KFP00040.1 - 0.006 16.0 0.4 19 4.8 0.0 4.5 5 0 0 5 5 5 0 XPC-binding domain DUF3731 PF12531.3 KFP00040.1 - 0.01 15.4 0.9 4 6.8 0.3 3.0 2 1 1 3 3 3 0 DNA-K related protein V-ATPase_H_C PF11698.3 KFP00040.1 - 0.061 13.2 0.3 4.7 7.1 0.0 3.5 4 0 0 4 4 4 0 V-ATPase subunit H DUF2336 PF10098.4 KFP00040.1 - 0.13 11.4 6.0 0.11 11.7 0.3 3.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2336) PIP5K PF01504.13 KFP00041.1 - 1.1e-72 244.2 0.1 1.3e-72 243.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Arm PF00514.18 KFP00042.1 - 5.4e-44 146.5 23.1 1.2e-06 28.0 0.0 12.1 13 0 0 13 13 13 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP00042.1 - 1.4e-31 108.5 13.6 4.9e-07 29.9 1.3 7.0 1 1 4 7 7 7 7 HEAT repeats EDR1 PF14381.1 KFP00042.1 - 3.6e-29 101.8 0.0 6e-25 88.0 0.0 2.8 2 0 0 2 2 2 2 Ethylene-responsive protein kinase Le-CTR1 HEAT PF02985.17 KFP00042.1 - 8.3e-20 69.0 15.5 0.02 14.9 0.1 10.1 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KFP00042.1 - 3.1e-14 52.9 15.9 0.017 15.6 0.2 8.5 8 1 1 9 9 8 4 HEAT-like repeat Adaptin_N PF01602.15 KFP00042.1 - 2.3e-12 46.0 2.0 4.1e-09 35.3 1.0 3.2 1 1 1 3 3 3 3 Adaptin N terminal region V-ATPase_H_C PF11698.3 KFP00042.1 - 8.2e-09 35.4 1.4 0.18 11.7 0.0 5.7 3 2 3 7 7 7 2 V-ATPase subunit H Arm_2 PF04826.8 KFP00042.1 - 5.1e-08 32.3 4.6 0.00062 18.9 0.5 5.1 1 1 5 6 6 6 4 Armadillo-like V-ATPase_H_N PF03224.9 KFP00042.1 - 1.4e-07 31.0 0.4 0.0028 16.8 0.0 3.3 1 1 1 3 3 3 2 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFP00042.1 - 1.3e-06 27.0 7.8 9.6e-05 20.8 1.1 3.0 1 1 2 3 3 3 2 Proteasome non-ATPase 26S subunit Aconitase_B_N PF11791.3 KFP00042.1 - 0.00023 20.9 2.6 0.13 12.0 0.1 4.2 3 2 1 4 4 4 1 Aconitate B N-terminal domain Cnd1 PF12717.2 KFP00042.1 - 0.0031 17.3 0.4 2 8.2 0.0 4.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.7 KFP00042.1 - 0.033 13.5 2.0 4.5 6.6 0.0 4.7 5 1 1 6 6 6 0 Down-regulated in metastasis SelR PF01641.13 KFP00043.1 - 1.8e-28 98.7 0.1 2.3e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 SelR domain HNH_5 PF14279.1 KFP00043.1 - 0.024 14.6 0.2 0.033 14.1 0.1 1.4 1 1 0 1 1 1 0 HNH endonuclease DUF281 PF03436.8 KFP00043.1 - 0.047 13.7 0.2 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF281) DUF4182 PF13790.1 KFP00043.1 - 0.077 12.8 0.5 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) DUF2296 PF10058.4 KFP00043.1 - 0.093 12.4 0.1 0.1 12.3 0.1 1.4 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) HECT_2 PF09814.4 KFP00043.1 - 0.095 11.3 0.0 0.095 11.3 0.0 1.0 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 KFP00043.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 KFP00043.1 - 0.13 12.0 0.6 0.43 10.4 0.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon GPW_gp25 PF04965.9 KFP00044.1 - 0.0068 15.9 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Gene 25-like lysozyme SPR1 PF15356.1 KFP00044.1 - 0.082 13.2 2.4 0.11 12.8 1.6 1.3 1 1 0 1 1 1 0 Psoriasis susceptibility locus 2 OTU PF02338.14 KFP00045.1 - 2.6e-21 76.4 0.0 4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFP00045.1 - 0.0045 16.3 0.1 0.12 11.6 0.1 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain RhoGAP PF00620.22 KFP00047.1 - 2.1e-50 170.2 0.0 4.4e-50 169.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.1 KFP00047.1 - 3.7e-14 52.8 0.0 1.2e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFP00047.1 - 2.8e-13 49.9 0.2 2.8e-13 49.9 0.1 2.9 3 0 0 3 3 3 1 PH domain PDZ PF00595.19 KFP00047.1 - 1.4e-10 41.1 0.1 4.7e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP00047.1 - 7.9e-07 28.8 0.1 2.7e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PH_11 PF15413.1 KFP00047.1 - 0.0088 16.2 1.3 0.025 14.8 0.1 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Pribosyltran PF00156.22 KFP00048.1 - 8e-07 28.8 0.0 0.023 14.4 0.0 2.1 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Enkurin PF13864.1 KFP00049.1 - 1e-26 93.0 10.8 1e-26 93.0 7.5 2.7 3 1 0 3 3 3 1 Calmodulin-binding SBP_bac_7 PF03480.8 KFP00049.1 - 0.0059 15.7 1.7 0.01 14.9 1.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 RasGAP PF00616.14 KFP00049.1 - 0.16 11.6 3.0 0.29 10.7 2.0 1.4 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase SKI PF01202.17 KFP00050.1 - 1.8e-32 112.3 0.0 4e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Thr_synth_N PF14821.1 KFP00050.1 - 3.3e-14 52.6 0.0 9e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KFP00050.1 - 1.1e-11 44.6 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_17 PF13207.1 KFP00050.1 - 3.4e-10 40.8 0.0 1.1e-09 39.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFP00050.1 - 1.6e-05 25.1 0.0 0.0002 21.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KFP00050.1 - 7.1e-05 22.0 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KFP00050.1 - 0.00015 21.6 0.0 0.0013 18.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFP00050.1 - 0.00019 21.7 0.0 0.00075 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFP00050.1 - 0.0038 16.3 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 KFP00050.1 - 0.0045 16.0 0.0 0.0089 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KFP00050.1 - 0.04 13.3 0.1 0.099 12.0 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFP00050.1 - 0.044 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Acid_PPase PF12689.2 KFP00050.1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase ADK PF00406.17 KFP00050.1 - 0.05 13.4 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase AAA_22 PF13401.1 KFP00050.1 - 0.067 13.3 0.2 0.3 11.2 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 KFP00050.1 - 0.17 11.6 1.9 0.24 11.1 0.2 2.0 2 0 0 2 2 2 0 Part of AAA domain 7tm_3 PF00003.17 KFP00051.1 - 2.1e-20 73.0 20.7 3.5e-20 72.3 14.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Myosin_head PF00063.16 KFP00052.1 - 2.9e-201 670.1 3.1 2.9e-201 670.1 2.2 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Pkinase PF00069.20 KFP00052.1 - 1.2e-62 211.4 0.0 2.3e-62 210.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00052.1 - 6e-44 150.0 0.0 1.2e-43 149.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.22 KFP00052.1 - 1.6e-24 83.0 19.0 4.1e-05 22.8 0.1 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif Kinase-like PF14531.1 KFP00052.1 - 4.7e-05 22.4 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP00052.1 - 0.00076 19.2 0.0 0.63 9.7 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family AAA_22 PF13401.1 KFP00052.1 - 0.0049 16.9 0.1 0.035 14.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain Pyridoxal_deC PF00282.14 KFP00053.1 - 2.2e-131 437.7 0.0 2.6e-131 437.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFP00053.1 - 0.00012 20.9 0.0 0.0023 16.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFP00053.1 - 0.00034 19.8 0.0 0.0007 18.8 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase TNFR_c6 PF00020.13 KFP00054.1 - 1.5e-05 24.9 11.7 3.6e-05 23.7 8.1 1.7 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region EGF_CA PF07645.10 KFP00054.1 - 0.0098 15.8 0.6 0.0098 15.8 0.4 2.7 2 1 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 KFP00054.1 - 0.06 12.9 3.1 0.14 11.8 2.1 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like Laminin_N PF00055.12 KFP00054.1 - 2.8 6.8 5.5 3.5 6.5 3.6 1.5 1 1 0 1 1 1 0 Laminin N-terminal (Domain VI) EGF_2 PF07974.8 KFP00054.1 - 3.8 7.7 16.4 4.6 7.5 3.8 2.8 2 1 0 2 2 2 0 EGF-like domain RA PF00788.18 KFP00055.1 - 6.6e-14 52.1 1.8 5.1e-13 49.3 0.5 2.5 1 1 1 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KFP00055.1 - 2.2e-11 43.8 0.2 7.7e-11 42.1 0.1 2.0 1 0 0 1 1 1 1 PH domain 4HBT_3 PF13622.1 KFP00055.1 - 0.12 12.0 0.1 0.12 12.0 0.1 3.2 2 1 0 2 2 2 0 Thioesterase-like superfamily PH_11 PF15413.1 KFP00055.1 - 0.49 10.6 3.2 0.66 10.2 0.9 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain UPF0061 PF02696.9 KFP00056.1 - 6.8e-82 275.3 0.0 8e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family dTDP_sugar_isom PF00908.12 KFP00056.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase polyprenyl_synt PF00348.12 KFP00057.1 - 3e-54 183.6 0.1 3.7e-54 183.2 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KFP00057.1 - 0.00085 18.8 0.3 0.0015 17.9 0.2 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Abi_HHR PF07815.9 KFP00058.1 - 3e-34 116.9 0.4 5.8e-34 116.0 0.3 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.23 KFP00058.1 - 1.5e-09 37.0 0.7 2.5e-09 36.3 0.5 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP00058.1 - 1.8e-06 27.4 0.2 3.8e-06 26.3 0.1 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFP00058.1 - 0.084 12.3 0.1 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain ACBP PF00887.14 KFP00059.1 - 5.9e-27 93.1 0.1 1.1e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Podoplanin PF05808.6 KFP00059.1 - 0.13 11.8 0.2 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 Podoplanin Pkinase PF00069.20 KFP00060.1 - 1.3e-50 171.9 0.1 8e-30 103.8 0.7 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00060.1 - 1.7e-25 89.5 0.1 1.7e-18 66.6 0.9 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFP00060.1 - 0.00091 18.2 0.0 0.0079 15.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP00060.1 - 0.0021 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFP00060.1 - 0.023 13.7 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M41 PF01434.13 KFP00061.1 - 5.7e-75 251.4 2.7 9.9e-75 250.6 1.9 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFP00061.1 - 1.9e-41 141.3 0.0 6e-41 139.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP00061.1 - 3.5e-05 23.9 0.0 0.0029 17.7 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFP00061.1 - 9.8e-05 22.4 0.1 0.0043 17.0 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KFP00061.1 - 0.00012 21.8 0.0 0.00052 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFP00061.1 - 0.00022 22.0 0.0 0.0016 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFP00061.1 - 0.00028 19.7 0.2 0.00072 18.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 KFP00061.1 - 0.00029 19.9 0.0 0.00076 18.5 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KFP00061.1 - 0.0013 18.1 0.0 0.0044 16.4 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFP00061.1 - 0.002 17.8 0.2 0.0057 16.3 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KFP00061.1 - 0.0026 17.2 0.3 0.048 13.0 0.2 2.3 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFP00061.1 - 0.0054 15.8 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KFP00061.1 - 0.0063 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFP00061.1 - 0.0089 15.2 0.3 0.031 13.4 0.2 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFP00061.1 - 0.015 15.6 0.0 0.052 13.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.9 KFP00061.1 - 0.015 15.2 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFP00061.1 - 0.019 13.9 0.0 0.047 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFP00061.1 - 0.029 14.2 0.0 0.09 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFP00061.1 - 0.041 13.8 0.2 0.11 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain FumaraseC_C PF10415.4 KFP00061.1 - 0.39 10.8 3.9 1.9 8.6 1.0 3.1 3 0 0 3 3 3 0 Fumarase C C-terminus Patched PF02460.13 KFP00062.1 - 6e-173 576.8 7.9 7.1e-173 576.5 5.5 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KFP00062.1 - 2e-42 144.2 6.1 2e-42 144.2 4.2 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 KFP00062.1 - 1.6 6.0 10.4 2.9 5.1 7.2 1.5 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMPL PF03176.10 KFP00062.1 - 4.4 5.9 16.8 0.0067 15.1 2.1 2.3 2 0 0 2 2 2 0 MMPL family Acyl_transf_1 PF00698.16 KFP00063.1 - 7e-53 180.0 0.1 1.2e-52 179.2 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KFP00063.1 - 8.1e-51 172.2 0.0 2.3e-50 170.7 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KFP00063.1 - 6.3e-40 136.8 0.0 1.3e-39 135.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFP00063.1 - 1.2e-33 115.4 0.4 3.4e-33 113.9 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KFP00063.1 - 5.7e-31 107.7 0.0 9.5e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase 3Beta_HSD PF01073.14 KFP00063.1 - 0.014 14.1 0.1 0.052 12.2 0.1 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.1 KFP00063.1 - 0.037 13.7 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Homeobox_KN PF05920.6 KFP00064.1 - 9.1e-15 54.0 0.2 2e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFP00064.1 - 2.9e-05 23.6 0.5 7.1e-05 22.3 0.3 1.7 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP00064.1 - 0.073 12.1 0.2 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 KFP00064.1 - 0.074 13.1 0.8 0.15 12.1 0.5 1.6 1 0 0 1 1 1 0 Helicase associated domain Period_C PF12114.3 KFP00064.1 - 0.17 11.4 3.3 0.34 10.4 2.3 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DMAP_binding PF06464.6 KFP00064.1 - 0.85 10.2 3.8 9.5 6.8 1.4 3.0 2 1 0 2 2 2 0 DMAP1-binding Domain Arm PF00514.18 KFP00065.1 - 5.6e-61 200.4 17.8 6.2e-05 22.6 0.0 13.5 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP00065.1 - 5.8e-26 90.6 2.3 1.4e-07 31.7 0.0 6.8 3 3 3 6 6 6 6 HEAT repeats HEAT PF02985.17 KFP00065.1 - 7.5e-13 47.3 10.1 0.022 14.7 0.1 8.2 8 0 0 8 8 8 4 HEAT repeat Adaptin_N PF01602.15 KFP00065.1 - 1.1e-09 37.2 1.4 7.8e-07 27.7 0.1 3.1 1 1 2 3 3 3 3 Adaptin N terminal region Arm_2 PF04826.8 KFP00065.1 - 1.7e-07 30.6 1.9 0.34 9.9 0.0 6.7 3 2 4 8 8 8 1 Armadillo-like HEAT_EZ PF13513.1 KFP00065.1 - 2e-06 28.1 7.8 0.2 12.1 0.0 8.0 8 1 1 9 9 9 2 HEAT-like repeat KAP PF05804.7 KFP00065.1 - 1.6e-05 23.1 0.0 0.08 10.8 0.0 3.4 3 1 0 3 3 3 3 Kinesin-associated protein (KAP) Proteasom_PSMB PF10508.4 KFP00065.1 - 2.5e-05 22.7 4.2 0.0013 17.1 0.0 3.3 3 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit UNC45-central PF11701.3 KFP00065.1 - 0.00016 21.3 13.1 0.023 14.3 0.0 4.8 4 1 1 5 5 5 2 Myosin-binding striated muscle assembly central V-ATPase_H_N PF03224.9 KFP00065.1 - 0.0015 17.6 0.8 7 5.6 0.3 4.2 3 1 0 3 3 3 2 V-ATPase subunit H Guanylate_kin PF00625.16 KFP00066.1 - 3.3e-49 166.8 0.3 9.6e-48 162.0 0.2 2.2 1 1 0 1 1 1 1 Guanylate kinase L27 PF02828.11 KFP00066.1 - 1.2e-21 76.0 6.4 2.3e-10 40.0 0.2 2.6 2 0 0 2 2 2 2 L27 domain PDZ PF00595.19 KFP00066.1 - 2.2e-13 50.1 0.8 5e-13 49.0 0.6 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.12 KFP00066.1 - 4.7e-08 32.3 0.0 1.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP00066.1 - 8.9e-08 31.3 0.3 8.8e-07 28.2 0.1 2.6 2 1 0 2 2 2 1 SH3 domain PDZ_2 PF13180.1 KFP00066.1 - 3.1e-05 23.7 0.1 0.00011 21.9 0.1 2.0 1 0 0 1 1 1 1 PDZ domain SH3_9 PF14604.1 KFP00066.1 - 0.00032 20.2 0.0 0.00072 19.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Tricorn_PDZ PF14685.1 KFP00066.1 - 0.062 13.0 0.0 0.42 10.4 0.0 2.3 2 1 0 2 2 2 0 Tricorn protease PDZ domain DUF2968 PF11180.3 KFP00067.1 - 6e-05 22.5 4.3 6.7e-05 22.3 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Filament PF00038.16 KFP00067.1 - 0.00041 19.9 6.3 0.00048 19.7 4.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFP00067.1 - 0.00062 17.6 5.9 0.00064 17.5 4.1 1.0 1 0 0 1 1 1 1 Myosin tail ADIP PF11559.3 KFP00067.1 - 0.0012 18.7 7.0 0.0014 18.5 4.8 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 KFP00067.1 - 0.0021 18.1 6.8 0.0025 17.8 4.7 1.1 1 0 0 1 1 1 1 DivIVA protein Tropomyosin PF00261.15 KFP00067.1 - 0.0026 16.8 6.8 0.003 16.6 4.7 1.1 1 0 0 1 1 1 1 Tropomyosin Bacillus_HBL PF05791.6 KFP00067.1 - 0.0029 17.0 3.8 0.0044 16.4 2.6 1.4 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) YlqD PF11068.3 KFP00067.1 - 0.003 17.6 5.4 0.0035 17.3 3.7 1.2 1 0 0 1 1 1 1 YlqD protein APG6 PF04111.7 KFP00067.1 - 0.0039 16.2 7.2 0.0043 16.1 5.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 ERM PF00769.14 KFP00067.1 - 0.0042 16.6 4.7 0.0047 16.4 3.3 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF4047 PF13256.1 KFP00067.1 - 0.0069 16.3 4.7 0.0084 16.0 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4047) DUF3086 PF11285.3 KFP00067.1 - 0.0096 14.7 1.1 0.01 14.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) Apolipoprotein PF01442.13 KFP00067.1 - 0.01 15.3 3.2 0.012 15.1 2.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Laminin_I PF06008.9 KFP00067.1 - 0.01 15.1 5.0 0.012 14.8 3.5 1.2 1 0 0 1 1 1 0 Laminin Domain I Lipoprotein_16 PF03923.8 KFP00067.1 - 0.012 15.0 0.6 0.017 14.4 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized lipoprotein Tropomyosin_1 PF12718.2 KFP00067.1 - 0.013 15.3 7.4 0.017 14.9 5.1 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 KFP00067.1 - 0.014 15.6 7.5 0.024 14.9 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF3393 PF11873.3 KFP00067.1 - 0.018 14.5 0.8 0.021 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) RmuC PF02646.11 KFP00067.1 - 0.018 13.8 2.3 0.022 13.6 1.6 1.1 1 0 0 1 1 1 0 RmuC family GAS PF13851.1 KFP00067.1 - 0.019 14.1 11.6 0.058 12.5 6.5 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 KFP00067.1 - 0.019 13.4 3.3 0.02 13.4 2.3 1.1 1 0 0 1 1 1 0 AAA domain Herpes_UL6 PF01763.11 KFP00067.1 - 0.026 12.7 3.1 0.028 12.6 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Prefoldin_3 PF13758.1 KFP00067.1 - 0.04 13.6 1.9 0.063 13.0 1.3 1.5 1 1 0 1 1 1 0 Prefoldin subunit Atg14 PF10186.4 KFP00067.1 - 0.042 12.7 4.4 0.044 12.7 3.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PEP-utilisers_N PF05524.8 KFP00067.1 - 0.043 13.6 0.7 0.054 13.3 0.5 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Rootletin PF15035.1 KFP00067.1 - 0.046 13.6 9.0 0.058 13.3 6.2 1.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ArsC PF03960.10 KFP00067.1 - 0.047 13.7 1.2 0.14 12.2 0.1 2.0 1 1 1 2 2 2 0 ArsC family DUF4140 PF13600.1 KFP00067.1 - 0.048 14.0 0.5 0.048 14.0 0.3 1.6 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) ApoLp-III PF07464.6 KFP00067.1 - 0.054 13.5 4.4 0.059 13.3 3.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) V_ATPase_I PF01496.14 KFP00067.1 - 0.061 11.1 2.6 0.064 11.1 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 KFP00067.1 - 0.063 13.2 6.0 0.073 13.0 4.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.3 KFP00067.1 - 0.069 12.4 4.6 0.082 12.1 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FliJ PF02050.11 KFP00067.1 - 0.087 12.8 9.3 0.11 12.5 6.5 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein Kinetocho_Slk19 PF12709.2 KFP00067.1 - 0.093 12.8 7.3 1 9.4 3.5 2.6 1 1 1 2 2 2 0 Central kinetochore-associated Mnd1 PF03962.10 KFP00067.1 - 0.095 12.3 6.3 0.1 12.2 4.3 1.1 1 0 0 1 1 1 0 Mnd1 family CCDC155 PF14662.1 KFP00067.1 - 0.1 12.2 11.9 0.2 11.2 8.3 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Nup88 PF10168.4 KFP00067.1 - 0.11 10.3 6.0 0.12 10.1 4.2 1.0 1 0 0 1 1 1 0 Nuclear pore component Seryl_tRNA_N PF02403.17 KFP00067.1 - 0.11 12.5 8.0 0.39 10.7 5.1 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Striatin PF08232.7 KFP00067.1 - 0.11 12.7 6.0 0.15 12.4 4.1 1.1 1 0 0 1 1 1 0 Striatin family Sec2p PF06428.6 KFP00067.1 - 0.13 12.1 8.8 0.23 11.3 6.0 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p CENP-F_leu_zip PF10473.4 KFP00067.1 - 0.13 12.1 13.4 0.22 11.3 9.3 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KFP00067.1 - 0.14 10.8 11.1 0.17 10.5 2.9 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein HR1 PF02185.11 KFP00067.1 - 0.17 11.6 9.1 0.093 12.4 4.6 1.9 1 1 1 2 2 2 0 Hr1 repeat IncA PF04156.9 KFP00067.1 - 0.17 11.4 13.0 0.29 10.7 9.0 1.5 1 1 0 1 1 1 0 IncA protein DUF16 PF01519.11 KFP00067.1 - 0.19 11.9 3.6 0.25 11.5 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.7 KFP00067.1 - 0.19 12.0 7.7 0.3 11.4 4.5 1.9 1 1 1 2 2 2 0 SlyX Cortex-I_coil PF09304.5 KFP00067.1 - 0.2 11.6 10.3 0.18 11.8 6.5 1.4 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF4200 PF13863.1 KFP00067.1 - 0.24 11.3 9.8 0.42 10.5 6.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 KFP00067.1 - 0.24 11.2 4.0 0.39 10.5 2.8 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.3 KFP00067.1 - 0.25 9.9 2.0 0.27 9.8 1.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0242 PF06785.6 KFP00067.1 - 0.27 9.8 8.1 0.31 9.6 5.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF4600 PF15372.1 KFP00067.1 - 0.3 11.3 8.4 0.74 10.0 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) FAA_hydrolase_N PF09298.6 KFP00067.1 - 0.3 11.0 2.3 0.41 10.6 1.5 1.3 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal TMF_DNA_bd PF12329.3 KFP00067.1 - 0.31 10.8 10.7 0.064 13.0 1.4 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 KFP00067.1 - 0.32 10.5 9.9 0.49 9.9 6.8 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) H-kinase_dim PF02895.9 KFP00067.1 - 0.38 11.1 3.4 1 9.7 2.3 1.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Ax_dynein_light PF10211.4 KFP00067.1 - 0.44 10.3 9.0 0.69 9.7 6.1 1.4 1 1 0 1 1 1 0 Axonemal dynein light chain Cob_adeno_trans PF01923.13 KFP00067.1 - 0.49 10.1 2.8 0.63 9.8 1.5 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Val_tRNA-synt_C PF10458.4 KFP00067.1 - 0.5 10.4 4.7 0.51 10.4 0.4 2.8 1 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF342 PF03961.8 KFP00067.1 - 0.51 8.7 6.5 0.54 8.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF948 PF06103.6 KFP00067.1 - 0.58 10.0 3.7 2.2 8.1 1.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2630 PF10944.3 KFP00067.1 - 0.62 10.2 4.6 0.89 9.7 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Kinesin-relat_1 PF12711.2 KFP00067.1 - 0.65 10.4 8.7 0.88 10.0 5.3 1.9 1 1 1 2 2 1 0 Kinesin motor Med9 PF07544.8 KFP00067.1 - 1.1 8.9 8.7 0.68 9.7 4.1 1.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 KFP00067.1 - 1.2 8.9 4.1 2.2 8.0 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Rho_Binding PF08912.6 KFP00067.1 - 1.3 9.3 9.4 1.5 9.1 4.1 2.2 1 1 1 2 2 2 0 Rho Binding Prefoldin_2 PF01920.15 KFP00067.1 - 1.5 8.6 11.9 1.1 9.0 6.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF904 PF06005.7 KFP00067.1 - 1.8 8.9 13.6 2.5 8.4 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF2762 PF10960.3 KFP00067.1 - 2.1 8.0 5.7 3.3 7.4 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) TPX2 PF06886.6 KFP00067.1 - 2.2 8.4 7.1 40 4.3 3.5 2.3 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) AATF-Che1 PF13339.1 KFP00067.1 - 2.6 8.2 7.7 7.7 6.6 5.3 1.8 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor NTR2 PF15458.1 KFP00067.1 - 2.8 7.0 9.5 1.3 8.1 4.9 1.6 1 1 0 1 1 1 0 Nineteen complex-related protein 2 XhlA PF10779.4 KFP00067.1 - 3.2 7.7 5.5 1.1 9.2 2.1 1.6 2 0 0 2 2 1 0 Haemolysin XhlA Spc24 PF08286.6 KFP00067.1 - 4.1 7.1 8.2 7.4 6.3 5.7 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 KFP00067.1 - 4.8 6.7 11.0 4.5 6.8 5.6 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF2681 PF10883.3 KFP00067.1 - 5.1 7.3 7.9 8.3 6.6 4.8 1.7 1 1 1 2 2 1 0 Protein of unknown function (DUF2681) WW PF00397.21 KFP00068.1 - 8.7e-10 38.2 0.9 1.6e-09 37.4 0.6 1.5 1 0 0 1 1 1 1 WW domain BAMBI PF06211.7 KFP00069.1 - 5.8e-46 154.9 11.7 5.8e-46 154.9 8.1 1.7 2 0 0 2 2 2 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Activin_recp PF01064.18 KFP00069.1 - 0.0003 21.3 11.8 0.0003 21.3 8.2 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain DUF1049 PF06305.6 KFP00069.1 - 0.13 11.7 1.0 0.24 10.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) YajC PF02699.10 KFP00069.1 - 0.16 11.6 0.2 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit BatD PF13584.1 KFP00069.1 - 0.17 10.4 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance KASH PF10541.4 KFP00069.1 - 0.56 10.0 6.9 5.8 6.8 0.5 2.5 2 0 0 2 2 2 0 Nuclear envelope localisation domain NUFIP1 PF10453.4 KFP00070.1 - 6.2e-23 80.0 6.0 2.1e-22 78.3 4.1 2.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.3 KFP00070.1 - 0.0007 19.6 2.9 0.0016 18.5 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1644 PF07800.7 KFP00070.1 - 1.5 8.6 9.3 0.085 12.7 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) DUF3752 PF12572.3 KFP00071.1 - 1.2e-31 109.9 17.5 1.2e-31 109.9 12.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3752) TFIIF_beta PF02270.10 KFP00072.1 - 3.2e-77 260.0 5.7 9.3e-76 255.2 3.9 2.0 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit BTB_2 PF02214.17 KFP00073.1 - 7.5e-18 64.5 0.0 1.8e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TCTP PF00838.12 KFP00075.1 - 5.8e-57 192.2 0.1 6.6e-57 192.0 0.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein URO-D PF01208.12 KFP00075.1 - 0.09 11.6 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Phage_int_SAM_4 PF13495.1 KFP00075.1 - 0.1 12.9 0.3 0.15 12.4 0.2 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Mito_carr PF00153.22 KFP00076.1 - 6.5e-49 163.6 0.1 3.8e-25 87.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.10 KFP00077.1 - 1.9e-74 248.5 6.9 1.9e-74 248.5 4.8 3.8 5 0 0 5 5 5 1 Sec34-like family CLTH PF10607.4 KFP00077.1 - 0.0056 16.3 6.0 0.024 14.3 0.8 3.3 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Laminin_I PF06008.9 KFP00077.1 - 0.018 14.3 0.5 0.018 14.3 0.3 3.1 4 0 0 4 4 4 0 Laminin Domain I PP2C_C PF07830.8 KFP00077.1 - 0.026 14.6 0.7 0.27 11.3 0.1 2.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Aha1_N PF09229.6 KFP00077.1 - 0.15 11.8 2.3 0.42 10.4 0.2 2.7 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal CHASE3 PF05227.8 KFP00077.1 - 0.65 9.6 9.2 5.2 6.7 0.0 4.2 5 1 0 5 5 5 0 CHASE3 domain NPV_P10 PF05531.7 KFP00077.1 - 0.76 10.0 4.4 8.8 6.6 0.1 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 KFP00077.1 - 1.9 8.6 8.7 4.8 7.3 0.5 4.4 4 2 0 4 4 4 0 Syntaxin Chibby PF14645.1 KFP00079.1 - 0.0004 20.2 1.0 0.0004 20.2 0.7 3.1 3 1 0 3 3 3 1 Chibby family DegS PF05384.6 KFP00079.1 - 0.016 14.4 0.2 0.047 12.8 0.1 1.7 1 0 0 1 1 1 0 Sensor protein DegS Stomoxyn PF11585.3 KFP00079.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn TSC22 PF01166.13 KFP00079.1 - 0.56 10.2 5.2 2.6 8.0 0.1 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Med28 PF11594.3 KFP00079.1 - 3.8 7.8 7.8 13 6.1 0.7 2.7 2 1 0 2 2 2 0 Mediator complex subunit 28 Peptidase_M14 PF00246.19 KFP00080.1 - 2.7e-84 283.0 0.0 3.3e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFP00080.1 - 3e-08 33.2 0.7 6.3e-08 32.1 0.5 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide CH PF00307.26 KFP00081.1 - 1.5e-82 272.7 0.6 9.8e-23 80.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFP00081.1 - 1.2e-11 44.5 0.0 3.6e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP00081.1 - 7.3e-10 37.4 0.5 3.5e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP00081.1 - 1.2e-09 37.1 0.3 2.5e-05 23.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain CAMSAP_CH PF11971.3 KFP00081.1 - 1.2e-07 31.2 0.1 1.4e-06 27.8 0.0 2.8 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_5 PF13202.1 KFP00081.1 - 0.00038 19.6 0.9 0.18 11.2 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFP00081.1 - 0.0012 18.3 0.1 0.0049 16.4 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain pair LRR_8 PF13855.1 KFP00083.1 - 1.9e-23 81.9 12.8 4e-09 36.0 1.4 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP00083.1 - 8.6e-23 79.4 16.0 1.2e-07 31.1 0.2 5.6 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP00083.1 - 1.6e-16 57.7 16.0 0.02 14.8 0.4 9.1 8 0 0 8 8 8 5 Leucine Rich Repeat CH PF00307.26 KFP00083.1 - 1.4e-10 41.1 0.0 4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_7 PF13504.1 KFP00083.1 - 1.7e-10 39.3 12.8 0.47 10.8 0.2 7.9 7 0 0 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 KFP00083.1 - 7.2e-07 28.6 10.6 0.95 9.7 0.2 7.5 9 0 0 9 9 9 2 Leucine Rich repeat CAMSAP_CH PF11971.3 KFP00083.1 - 9.8e-05 21.9 0.0 0.00032 20.3 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 KFP00083.1 - 0.00018 21.4 0.0 0.0043 17.0 0.0 2.5 2 0 0 2 2 2 1 CDC24 Calponin 7tm_1 PF00001.16 KFP00085.1 - 3.3e-72 242.7 13.6 4.6e-72 242.2 9.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00085.1 - 4e-15 55.6 17.8 6.1e-15 55.0 12.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP00085.1 - 0.00071 18.7 17.1 0.00071 18.7 11.9 2.8 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1385 PF07136.6 KFP00085.1 - 0.0028 16.7 3.9 0.0081 15.2 0.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1385) ATP-grasp_2 PF08442.5 KFP00086.1 - 2.3e-76 255.6 0.9 3.9e-76 254.9 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KFP00086.1 - 1.6e-27 96.0 2.4 3.5e-27 94.8 1.7 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KFP00086.1 - 1.4e-09 37.5 0.2 2.7e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KFP00086.1 - 0.031 13.8 0.9 0.084 12.4 0.6 1.7 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KFP00086.1 - 0.044 13.2 0.2 0.26 10.7 0.0 2.4 3 0 0 3 3 3 0 RimK-like ATP-grasp domain HipA_N PF07805.7 KFP00086.1 - 0.073 13.3 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 HipA-like N-terminal domain nsp7 PF08716.5 KFP00086.1 - 0.11 12.8 1.1 1.8 8.9 0.1 2.5 2 0 0 2 2 2 0 nsp7 replicase NUDIX PF00293.23 KFP00087.1 - 0.0037 16.9 0.1 0.005 16.4 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Med4 PF10018.4 KFP00088.1 - 4.4e-38 130.5 0.2 6.9e-38 129.9 0.1 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin PF00261.15 KFP00088.1 - 0.0014 17.7 4.1 0.0019 17.3 2.8 1.1 1 0 0 1 1 1 1 Tropomyosin DUF2019 PF09450.5 KFP00088.1 - 0.044 13.6 0.1 3.1 7.7 0.3 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF2019) Trans_reg_C PF00486.23 KFP00088.1 - 0.048 13.5 1.1 2.9 7.8 0.1 2.8 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Stathmin PF00836.14 KFP00088.1 - 0.14 11.7 6.5 0.25 10.9 4.5 1.4 1 0 0 1 1 1 0 Stathmin family Atg14 PF10186.4 KFP00088.1 - 0.34 9.8 4.7 0.42 9.4 3.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1682 PF07946.9 KFP00088.1 - 0.37 9.6 6.1 0.47 9.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF724 PF05266.9 KFP00088.1 - 0.53 9.8 5.9 0.75 9.3 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BRICHOS PF04089.9 KFP00089.1 - 4.3e-28 97.0 0.0 7.1e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 BRICHOS domain RB_A PF01858.12 KFP00090.1 - 3.3e-81 271.5 0.7 3.3e-81 271.5 0.5 2.0 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain Rb_C PF08934.5 KFP00090.1 - 8e-81 269.1 8.0 9.5e-81 268.9 2.5 2.4 2 0 0 2 2 2 1 Rb C-terminal domain RB_B PF01857.15 KFP00090.1 - 3.8e-37 126.8 10.9 1.1e-36 125.2 4.4 2.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.3 KFP00090.1 - 4.8e-33 113.4 7.3 2.3e-30 104.7 3.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3452) 7tm_1 PF00001.16 KFP00091.1 - 1.7e-59 201.0 31.2 1.7e-59 201.0 21.6 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP00091.1 - 0.032 13.3 39.0 0.23 10.5 26.8 2.0 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx RCC1 PF00415.13 KFP00092.1 - 9.8e-65 214.5 21.8 7.4e-16 58.1 0.9 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFP00092.1 - 1.8e-31 107.0 25.0 2.8e-11 42.6 0.8 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KFP00092.1 - 3.6e-20 72.0 0.9 2.5e-17 62.8 0.0 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 KFP00092.1 - 4.5e-06 26.4 1.8 0.00077 19.2 0.2 3.2 2 1 1 3 3 3 1 BTB And C-terminal Kelch DUF4213 PF13938.1 KFP00092.1 - 0.034 14.2 0.1 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) CBM_X PF06204.6 KFP00092.1 - 3.4 7.2 12.1 13 5.3 0.1 4.6 5 0 0 5 5 5 0 Putative carbohydrate binding domain Kelch_2 PF07646.10 KFP00092.1 - 4.1 7.3 8.1 13 5.7 0.1 4.6 5 0 0 5 5 5 0 Kelch motif fn3 PF00041.16 KFP00094.1 - 7.5e-38 128.5 5.0 7e-12 45.3 0.0 5.0 4 1 0 4 4 4 4 Fibronectin type III domain SusE PF14292.1 KFP00094.1 - 6.9e-07 29.1 0.5 0.25 11.1 0.0 4.3 4 0 0 4 4 4 2 SusE outer membrane protein Interfer-bind PF09294.5 KFP00094.1 - 0.00032 20.6 1.3 0.035 14.1 0.1 3.0 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III 7tm_1 PF00001.16 KFP00095.1 - 1.4e-45 155.4 22.0 1.8e-45 155.1 15.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00095.1 - 0.00064 18.9 22.6 0.0013 17.9 15.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Srg PF02118.16 KFP00095.1 - 5.1 6.4 26.9 0.12 11.7 13.3 1.9 1 1 0 2 2 2 0 Srg family chemoreceptor I-set PF07679.11 KFP00096.1 - 1e-72 240.0 0.0 2e-13 49.9 0.0 6.9 7 0 0 7 7 6 6 Immunoglobulin I-set domain fn3 PF00041.16 KFP00096.1 - 1.1e-61 204.9 15.8 7.6e-14 51.6 0.2 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_2 PF13895.1 KFP00096.1 - 7.8e-56 186.1 0.1 2.5e-09 37.1 0.0 6.5 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFP00096.1 - 2.5e-51 171.9 1.1 6.2e-08 33.0 0.0 7.5 6 0 0 6 6 6 6 Immunoglobulin domain ig PF00047.20 KFP00096.1 - 3.6e-33 113.5 0.0 1.5e-06 28.2 0.0 8.1 7 0 0 7 7 7 5 Immunoglobulin domain Bravo_FIGEY PF13882.1 KFP00096.1 - 1.8e-32 112.0 9.3 3.8e-32 111.0 6.4 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.12 KFP00096.1 - 1e-16 60.8 6.0 0.012 15.5 0.2 8.2 6 5 0 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP00096.1 - 1.2e-14 53.9 0.2 0.068 13.0 0.0 6.6 6 0 0 6 6 6 3 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.5 KFP00096.1 - 0.0008 19.4 0.7 2.5 8.1 0.0 4.5 5 0 0 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III BiPBP_C PF06832.7 KFP00096.1 - 0.00088 19.1 0.0 3.8 7.4 0.0 3.4 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family Herpes_gE PF02480.11 KFP00096.1 - 0.0013 17.0 0.0 2.9 6.0 0.0 3.9 3 1 0 4 4 4 1 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 KFP00096.1 - 0.0049 16.6 3.0 8 6.2 0.0 3.8 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain LST1 PF05083.8 KFP00096.1 - 0.012 15.5 0.4 5.8 6.9 0.0 3.9 4 0 0 4 4 4 0 LST-1 protein I-set PF07679.11 KFP00097.1 - 2.7e-56 187.3 6.0 7.3e-12 44.9 0.0 8.3 6 3 1 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP00097.1 - 2.3e-45 152.5 0.0 1.6e-09 37.7 0.0 6.6 4 2 2 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 KFP00097.1 - 5.8e-38 128.8 11.8 5.3e-17 61.7 1.3 4.8 4 0 0 4 4 4 4 Fibronectin type III domain Ig_3 PF13927.1 KFP00097.1 - 2.2e-34 117.7 0.0 7e-07 29.6 0.0 7.4 7 0 0 7 7 6 5 Immunoglobulin domain V-set PF07686.12 KFP00097.1 - 6e-31 106.7 6.9 1.2e-06 28.4 0.0 8.6 6 4 3 9 9 9 5 Immunoglobulin V-set domain ig PF00047.20 KFP00097.1 - 7.4e-27 93.2 0.0 0.00011 22.3 0.0 6.9 6 0 0 6 6 6 6 Immunoglobulin domain C2-set_2 PF08205.7 KFP00097.1 - 4.4e-05 23.2 0.0 0.96 9.3 0.0 4.1 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.12 KFP00097.1 - 4.8e-05 23.0 2.6 0.077 12.7 0.0 4.7 4 2 0 4 4 4 1 Tissue factor Interfer-bind PF09294.5 KFP00097.1 - 0.00011 22.1 0.1 0.0016 18.4 0.1 2.7 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Sp38 PF07354.7 KFP00097.1 - 0.0024 16.5 0.0 2.4 6.7 0.0 3.1 3 0 0 3 3 3 2 Zona-pellucida-binding protein (Sp38) Big_3_4 PF13754.1 KFP00097.1 - 0.037 14.3 2.1 0.95 9.8 0.0 3.8 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Ndufs5 PF10200.4 KFP00098.1 - 1.2e-05 25.2 0.1 1.3e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Orn_Arg_deC_N PF02784.11 KFP00099.1 - 2e-60 204.1 0.0 2.5e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFP00099.1 - 3.2e-10 39.7 0.0 5.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ADK PF00406.17 KFP00100.1 - 2.1e-51 173.7 0.0 2.5e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFP00100.1 - 9.4e-14 50.7 0.0 3e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid IBR PF01485.16 KFP00101.1 - 2.1e-21 75.5 48.7 2.6e-14 52.8 11.3 3.4 3 1 0 3 3 3 2 IBR domain zf-RING_5 PF14634.1 KFP00101.1 - 0.0053 16.4 3.8 0.0053 16.4 2.6 4.5 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFP00101.1 - 0.0066 16.0 4.9 0.0066 16.0 3.4 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) EF-hand_1 PF00036.27 KFP00102.1 - 2.8e-27 91.8 6.3 2.1e-07 29.7 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFP00102.1 - 9e-26 89.8 1.2 1.2e-16 60.5 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP00102.1 - 5e-24 82.5 3.1 1.7e-07 30.2 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFP00102.1 - 7.4e-23 78.3 0.2 2.5e-06 26.8 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFP00102.1 - 1.6e-18 66.0 4.2 5.9e-09 35.4 0.1 3.7 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP00102.1 - 7.2e-08 32.4 0.1 0.00016 21.6 0.0 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFP00102.1 - 6.6e-07 29.0 0.8 0.22 11.2 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 KFP00102.1 - 0.00076 19.1 0.3 2.8 7.6 0.0 3.2 3 0 0 3 3 3 2 EF hand fn3 PF00041.16 KFP00103.1 - 1e-10 41.5 0.6 2.9e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain DUF4366 PF14283.1 KFP00103.1 - 0.089 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) tRNA-synt_1b PF00579.20 KFP00104.1 - 2.1e-74 250.2 0.0 2.7e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.15 KFP00104.1 - 7e-33 112.3 0.1 1.6e-32 111.1 0.1 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain Filament PF00038.16 KFP00108.1 - 1.7e-22 80.3 33.1 2.9e-22 79.5 23.0 1.4 1 1 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFP00108.1 - 0.00064 19.4 31.3 0.0078 15.9 3.4 4.0 2 2 1 3 3 3 2 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 KFP00108.1 - 0.0015 18.1 8.2 0.0015 18.1 5.7 3.4 2 1 2 4 4 4 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 KFP00108.1 - 0.0021 16.8 30.6 0.0051 15.5 7.5 2.6 2 1 1 3 3 3 2 Spc7 kinetochore protein Laminin_II PF06009.7 KFP00108.1 - 0.0069 16.1 17.5 0.18 11.5 3.2 3.2 2 1 1 3 3 3 2 Laminin Domain II Prp19 PF08606.6 KFP00108.1 - 0.0093 15.6 2.8 0.0093 15.6 1.9 2.7 3 0 0 3 3 2 1 Prp19/Pso4-like WEMBL PF05701.6 KFP00108.1 - 0.014 13.9 28.5 15 3.8 20.3 2.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light APG6 PF04111.7 KFP00108.1 - 0.016 14.2 30.8 0.01 14.9 8.2 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KFP00108.1 - 0.033 13.3 0.2 8.5 5.4 0.1 2.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KFP00108.1 - 0.059 13.2 43.0 0.19 11.5 7.5 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 KFP00108.1 - 0.1 12.6 30.4 0.79 9.7 0.1 6.2 4 1 1 5 5 5 0 bZIP transcription factor DUF4618 PF15397.1 KFP00108.1 - 0.13 11.5 25.6 0.032 13.5 1.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Cauli_AT PF03233.8 KFP00108.1 - 0.33 10.6 9.8 0.55 9.9 0.7 2.6 3 0 0 3 3 2 0 Aphid transmission protein DUF1664 PF07889.7 KFP00108.1 - 0.36 10.6 15.4 0.63 9.8 1.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 KFP00108.1 - 0.53 10.3 27.6 0.8 9.7 5.8 3.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Bacillus_HBL PF05791.6 KFP00108.1 - 0.63 9.3 12.4 2.8 7.2 0.9 3.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) TMCO5 PF14992.1 KFP00108.1 - 0.63 9.1 26.8 0.57 9.2 7.7 2.2 2 0 0 2 2 2 0 TMCO5 family Cob_adeno_trans PF01923.13 KFP00108.1 - 0.73 9.6 10.1 0.42 10.3 0.5 2.7 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Mnd1 PF03962.10 KFP00108.1 - 0.92 9.1 30.0 0.57 9.8 3.5 3.5 1 1 1 3 3 3 0 Mnd1 family DivIVA PF05103.8 KFP00108.1 - 1.2 9.1 25.0 16 5.5 5.6 4.0 2 2 0 2 2 2 0 DivIVA protein DUF972 PF06156.8 KFP00108.1 - 1.3 9.4 29.1 1.1 9.6 1.7 4.9 2 2 1 3 3 3 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 KFP00108.1 - 2.2 8.0 38.5 6.6 6.4 1.7 4.4 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.6 KFP00108.1 - 2.3 8.1 19.0 0.34 10.7 0.5 3.9 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2937 PF11157.3 KFP00108.1 - 2.9 7.1 7.4 1.4 8.1 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Prominin PF05478.6 KFP00108.1 - 3.9 4.8 14.7 1.5 6.3 1.2 2.7 1 1 0 2 2 2 0 Prominin FlaC_arch PF05377.6 KFP00108.1 - 4.6 7.2 20.1 4.7 7.1 1.1 5.5 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) Toxin_52 PF15605.1 KFP00108.1 - 6.3 6.7 9.8 8.6 6.3 0.4 3.7 3 2 2 5 5 5 0 Putative toxin 52 ATG16 PF08614.6 KFP00108.1 - 9.1 6.0 35.6 8.2 6.2 9.0 3.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) WD40 PF00400.27 KFP00109.1 - 8.3e-38 126.9 10.7 1.4e-08 34.2 0.0 6.2 5 1 1 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFP00109.1 - 2.3e-30 104.3 0.2 6.2e-30 102.9 0.1 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 KFP00109.1 - 0.0001 22.1 0.2 0.046 13.4 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Capsid_NCLDV PF04451.7 KFP00109.1 - 0.025 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Archease PF01951.11 KFP00110.1 - 3.4e-47 159.8 0.1 4.2e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) BTB PF00651.26 KFP00111.1 - 4.2e-26 91.1 0.6 7.9e-26 90.2 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP00111.1 - 2.5e-09 36.9 2.3 2.5e-09 36.9 1.6 4.0 3 0 0 3 3 3 1 Zinc-finger double domain DUF3342 PF11822.3 KFP00111.1 - 2.1e-06 27.1 0.2 2.1e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2_4 PF13894.1 KFP00111.1 - 3.3e-05 23.9 14.4 0.00013 22.0 1.1 4.1 4 1 0 4 4 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP00111.1 - 0.00026 21.1 1.4 0.00026 21.1 1.0 4.3 5 0 0 5 5 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFP00111.1 - 0.0015 18.5 2.2 0.02 15.0 0.1 3.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP00111.1 - 0.0021 18.2 2.3 0.046 13.9 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type BTB_2 PF02214.17 KFP00111.1 - 0.0081 16.3 0.6 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF1722 PF08349.6 KFP00111.1 - 0.015 15.1 0.1 0.27 11.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) Trm112p PF03966.11 KFP00111.1 - 0.061 13.6 1.6 0.19 12.1 1.1 1.8 1 0 0 1 1 1 0 Trm112p-like protein DUF3212 PF11486.3 KFP00111.1 - 0.079 12.7 0.2 0.18 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3212) zf-Di19 PF05605.7 KFP00111.1 - 0.12 12.5 11.3 0.8 9.8 4.9 3.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 KFP00111.1 - 0.12 12.3 7.2 0.92 9.5 0.8 3.8 2 1 0 2 2 2 0 Zinc ribbon domain DUF2296 PF10058.4 KFP00111.1 - 0.87 9.3 7.0 15 5.4 0.0 3.3 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Elf1 PF05129.8 KFP00111.1 - 3.8 7.2 10.9 0.37 10.5 0.7 3.3 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-H2C2_5 PF13909.1 KFP00111.1 - 6.6 7.1 15.7 0.059 13.6 1.7 3.5 3 0 0 3 3 2 0 C2H2-type zinc-finger domain BTB PF00651.26 KFP00112.1 - 4.7e-27 94.1 0.4 7.4e-27 93.5 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP00112.1 - 6e-09 35.7 2.4 6e-09 35.7 1.7 3.8 3 1 0 3 3 3 1 Zinc-finger double domain DUF3342 PF11822.3 KFP00112.1 - 1.9e-06 27.2 0.1 1.9e-06 27.2 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2 PF00096.21 KFP00112.1 - 1.5e-05 25.0 22.7 6.3e-05 23.0 1.1 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP00112.1 - 2.4e-05 24.3 21.7 0.00031 20.8 0.9 3.6 4 0 0 4 4 3 2 C2H2-type zinc finger BTB_2 PF02214.17 KFP00112.1 - 0.00064 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.2 KFP00112.1 - 0.014 15.5 2.7 0.11 12.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFP00112.1 - 0.02 15.0 2.2 0.02 15.0 1.5 2.9 3 0 0 3 3 2 0 C2H2-type zinc-finger domain Glyoxal_oxid_N PF07250.6 KFP00112.1 - 0.05 12.6 0.0 0.84 8.6 0.0 2.2 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus DUF1722 PF08349.6 KFP00112.1 - 0.053 13.3 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) zf-C2H2_jaz PF12171.3 KFP00112.1 - 0.18 11.9 2.4 0.54 10.4 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFP00112.1 - 0.61 10.0 8.2 5.7 6.9 2.8 3.6 2 1 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 KFP00112.1 - 0.87 9.3 5.7 0.17 11.5 0.8 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 KFP00112.1 - 2.4 8.0 16.9 4.6 7.1 3.7 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain BTB PF00651.26 KFP00113.1 - 9.8e-26 89.9 0.3 1.6e-25 89.2 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP00113.1 - 6.7e-07 29.3 8.2 7.1e-06 26.0 1.2 4.2 3 1 1 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP00113.1 - 8.2e-06 25.8 1.3 8.2e-06 25.8 0.9 4.5 5 0 0 5 5 5 1 Zinc finger, C2H2 type DUF3342 PF11822.3 KFP00113.1 - 1.7e-05 24.1 0.1 1.7e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2_4 PF13894.1 KFP00113.1 - 0.00011 22.2 1.7 0.00011 22.2 1.2 4.3 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP00113.1 - 0.0068 16.5 0.3 0.12 12.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP00113.1 - 0.0072 16.4 0.1 0.0072 16.4 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type SRC-1 PF08832.5 KFP00113.1 - 0.042 14.5 0.3 0.13 13.0 0.2 1.8 1 0 0 1 1 1 0 Steroid receptor coactivator RRN7 PF11781.3 KFP00113.1 - 5.7 6.5 9.4 12 5.4 0.2 3.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 BSD PF03909.12 KFP00114.1 - 1.4e-17 63.1 3.2 4.9e-17 61.4 0.1 2.3 2 0 0 2 2 2 1 BSD domain Arm PF00514.18 KFP00115.1 - 5.4e-89 289.3 18.3 4e-14 51.8 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP00115.1 - 5.3e-27 93.9 0.0 6.8e-09 35.8 0.0 5.6 2 1 3 6 6 6 4 HEAT repeats IBB PF01749.15 KFP00115.1 - 5.4e-26 90.5 2.3 9.8e-26 89.7 1.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFP00115.1 - 4.5e-22 77.8 5.1 1.1e-06 28.8 0.0 5.9 4 2 2 6 6 6 5 HEAT-like repeat HEAT PF02985.17 KFP00115.1 - 1.3e-12 46.6 14.9 0.0005 19.9 0.0 8.0 10 0 0 10 10 10 2 HEAT repeat Arm_2 PF04826.8 KFP00115.1 - 2.8e-08 33.1 0.0 0.0064 15.6 0.0 2.8 1 1 2 3 3 3 2 Armadillo-like RICTOR_V PF14668.1 KFP00115.1 - 1.8e-06 27.7 3.8 0.99 9.3 0.0 5.4 4 2 2 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 KFP00115.1 - 1.5e-05 24.9 0.0 0.25 11.2 0.0 4.4 2 1 3 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 KFP00115.1 - 0.00049 20.3 0.4 7.2 7.3 0.0 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 KFP00115.1 - 0.0042 15.4 0.1 0.12 10.6 0.0 2.6 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit Taxilin PF09728.4 KFP00116.1 - 4.3e-117 390.6 73.4 4.8e-117 390.4 50.9 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF869 PF05911.6 KFP00116.1 - 0.00076 17.8 10.1 0.00076 17.8 7.0 2.4 1 1 1 2 2 2 1 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 KFP00116.1 - 0.95 7.8 48.8 0.041 12.3 8.1 2.1 1 1 1 2 2 2 0 AAA domain SpoVAD PF07451.6 KFP00116.1 - 5.2 5.4 7.8 5.5 5.3 0.6 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) GAS PF13851.1 KFP00116.1 - 8.2 5.5 71.5 4.8 6.3 5.9 3.9 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4061 PF13270.1 KFP00117.1 - 2.2e-38 130.2 2.3 2.9e-38 129.8 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) IQ PF00612.22 KFP00118.1 - 0.02 14.4 0.5 0.02 14.4 0.3 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif DCX PF03607.12 KFP00119.1 - 1.5e-19 69.3 0.0 1.8e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Doublecortin DCX PF03607.12 KFP00120.1 - 1.8e-13 49.8 0.0 2.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Doublecortin UPF0546 PF10639.4 KFP00121.1 - 3.3e-23 81.6 1.3 3.6e-23 81.5 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 WD40 PF00400.27 KFP00122.1 - 2.2e-34 116.0 1.3 2.4e-09 36.6 1.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KFP00122.1 - 0.054 11.6 0.1 0.26 9.3 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF4159 PF13709.1 KFP00122.1 - 0.076 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Ins_P5_2-kin PF06090.7 KFP00122.1 - 0.12 11.3 0.1 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase DUF3259 PF11652.3 KFP00123.1 - 1.2e-40 137.4 1.1 1.9e-40 136.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3259) DUF2388 PF09498.5 KFP00123.1 - 0.00035 20.1 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) DUF4164 PF13747.1 KFP00123.1 - 0.0025 17.9 1.3 0.0025 17.9 0.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) LURAP PF14854.1 KFP00123.1 - 0.016 14.8 0.1 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF4618 PF15397.1 KFP00123.1 - 0.048 13.0 0.1 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4404 PF14357.1 KFP00123.1 - 0.049 14.0 0.9 0.049 14.0 0.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Pkinase_Tyr PF07714.12 KFP00124.1 - 2.2e-97 325.2 0.0 2.7e-97 324.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP00124.1 - 2.5e-51 174.3 0.0 3.3e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP00124.1 - 1.3e-27 95.4 0.6 2.5e-27 94.4 0.4 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFP00124.1 - 7.1e-15 54.1 0.1 1.7e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP00124.1 - 1.5e-10 40.4 0.0 3.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP00124.1 - 2e-08 33.5 0.0 4.2e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Hist_deacetyl PF00850.14 KFP00125.1 - 6.5e-82 275.2 0.1 9.3e-82 274.7 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MARCKS PF02063.12 KFP00126.1 - 3.6e-12 46.7 43.6 1.1e-09 38.6 31.0 2.7 1 1 1 2 2 2 2 MARCKS family Tmp39 PF10271.4 KFP00127.1 - 1.9e-198 659.3 17.2 2.2e-198 659.1 12.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein KH_1 PF00013.24 KFP00128.1 - 6.2e-09 35.3 0.1 1.2e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFP00128.1 - 2.2e-08 33.5 0.1 4.2e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_5 PF13184.1 KFP00128.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 NusA-like KH domain KH_2 PF07650.12 KFP00128.1 - 0.092 12.3 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 KH domain Y_phosphatase PF00102.22 KFP00129.1 - 2.5e-12 46.6 0.0 7.1e-09 35.3 0.0 2.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFP00129.1 - 3.5e-09 36.3 0.0 4.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HPIP PF15226.1 KFP00130.1 - 0.1 12.6 0.5 0.2 11.7 0.2 1.6 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family 7tm_2 PF00002.19 KFP00131.1 - 1e-59 201.6 11.5 1.2e-59 201.3 7.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 KFP00131.1 - 0.031 13.4 11.8 0.046 12.8 8.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) NDUF_B12 PF08122.7 KFP00131.1 - 0.031 14.0 0.2 0.094 12.4 0.1 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF1129 PF06570.6 KFP00131.1 - 0.14 11.4 4.6 0.064 12.5 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) EF-hand_1 PF00036.27 KFP00132.1 - 1.5e-20 70.8 0.0 1e-06 27.6 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFP00132.1 - 5e-18 63.3 0.1 1.4e-06 27.6 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 KFP00132.1 - 2.7e-17 62.6 0.4 3.5e-07 30.2 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP00132.1 - 1e-16 59.3 0.7 1.3e-06 27.4 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFP00132.1 - 1.1e-08 34.5 0.1 0.0051 16.4 0.0 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_2 PF09068.6 KFP00132.1 - 0.00078 19.5 0.0 6 6.9 0.0 3.3 3 1 1 4 4 4 2 EF hand GUN4 PF05419.7 KFP00132.1 - 0.026 14.3 0.1 0.041 13.6 0.1 1.5 1 1 0 1 1 1 0 GUN4-like OST-HTH PF12872.2 KFP00132.1 - 0.065 13.0 0.0 0.23 11.3 0.0 2.0 1 1 0 1 1 1 0 OST-HTH/LOTUS domain Peptidase_C1 PF00112.18 KFP00133.1 - 5.7e-24 85.2 0.1 9.1e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Pacifastin_I PF05375.8 KFP00133.1 - 2.3e-06 27.0 2.8 1e-05 24.9 1.9 2.2 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Somatomedin_B PF01033.12 KFP00133.1 - 3.3e-05 23.7 13.6 3.3e-05 23.7 9.4 2.3 2 0 0 2 2 2 1 Somatomedin B domain KCNQ_channel PF03520.9 KFP00134.1 - 9.2e-85 283.0 0.2 1.1e-84 282.7 0.1 1.1 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel TMEM95 PF15203.1 KFP00134.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 TMEM95 family Ion_trans_2 PF07885.11 KFP00135.1 - 6.5e-15 54.6 3.3 7.4e-15 54.4 2.3 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KFP00135.1 - 6.1e-08 32.1 2.7 7.1e-08 31.9 1.8 1.1 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.21 KFP00135.1 - 0.0076 15.9 0.9 0.012 15.2 0.6 1.4 1 1 0 1 1 1 1 Ligand-gated ion channel DUF2798 PF11391.3 KFP00135.1 - 0.14 11.9 3.3 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) FAD-SLDH PF12318.3 KFP00135.1 - 1.2 8.7 4.4 7.3 6.2 3.1 1.9 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase CBFD_NFYB_HMF PF00808.18 KFP00136.1 - 4.4e-22 77.9 2.7 1.9e-21 75.8 1.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFP00136.1 - 2.2e-12 46.9 0.3 7.1e-12 45.2 0.2 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KFP00136.1 - 0.098 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X YfhO PF09586.5 KFP00136.1 - 4.8 5.0 13.4 5.8 4.7 9.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO C2 PF00168.25 KFP00137.1 - 1.3e-13 50.5 0.0 2.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.13 KFP00138.1 - 2.7e-32 111.0 0.6 4.5e-32 110.2 0.1 1.6 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf CUB PF00431.15 KFP00139.1 - 3.1e-276 896.3 0.0 1.7e-25 89.2 0.0 12.3 12 0 0 12 12 12 12 CUB domain Sushi PF00084.15 KFP00139.1 - 1.8e-259 838.3 176.7 6.2e-12 45.6 0.8 27.5 27 0 0 27 27 27 27 Sushi domain (SCR repeat) CUB_2 PF02408.15 KFP00139.1 - 5.2e-22 77.6 19.9 0.00011 21.7 0.4 11.2 12 0 0 12 12 12 7 CUB-like domain HRM PF02793.17 KFP00139.1 - 0.026 14.5 74.9 0.21 11.6 0.1 16.2 14 2 1 15 15 15 0 Hormone receptor domain CUB PF00431.15 KFP00140.1 - 1.7e-22 79.5 0.0 2.2e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 CUB domain SAG PF04092.8 KFP00141.1 - 0.19 12.1 1.8 0.24 11.7 1.2 1.3 1 1 0 1 1 1 0 SRS domain Connexin PF00029.14 KFP00143.1 - 1.3e-47 160.2 0.3 1.3e-47 160.2 0.2 1.8 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFP00143.1 - 6.5e-27 93.1 6.4 1.6e-26 91.8 4.4 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain CcmB PF03379.8 KFP00143.1 - 0.043 13.0 0.7 0.07 12.3 0.0 1.7 2 0 0 2 2 2 0 CcmB protein Oxidored_q2 PF00420.19 KFP00143.1 - 0.15 11.6 3.5 2.1 7.9 0.0 3.1 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Connexin PF00029.14 KFP00144.1 - 5.6e-51 171.1 0.4 5.6e-51 171.1 0.3 1.7 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFP00144.1 - 1.1e-25 89.2 4.3 2.7e-25 87.9 3.0 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain UCR_TM PF02921.9 KFP00144.1 - 0.04 14.1 0.7 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region PRA1 PF03208.14 KFP00144.1 - 0.18 11.1 2.2 0.96 8.7 0.0 2.8 3 1 0 3 3 3 0 PRA1 family protein Ninjurin PF04923.7 KFP00144.1 - 0.19 11.4 0.9 1.2 8.9 0.0 2.4 3 0 0 3 3 3 0 Ninjurin DUF912 PF06024.7 KFP00144.1 - 0.22 11.6 1.3 6.7 6.8 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Connexin PF00029.14 KFP00145.1 - 4.5e-53 177.8 0.1 8.3e-53 176.9 0.1 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFP00145.1 - 6.9e-33 112.2 0.9 1.9e-32 110.8 0.7 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin43 PF03508.8 KFP00145.1 - 0.00055 19.1 4.2 0.00097 18.3 2.9 1.4 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) AA_permease_2 PF13520.1 KFP00145.1 - 0.015 13.8 1.1 0.16 10.4 0.1 2.2 2 1 0 2 2 2 0 Amino acid permease DoxX_2 PF13564.1 KFP00147.1 - 0.02 14.8 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 DoxX-like family DoxX PF07681.7 KFP00147.1 - 0.039 14.3 0.2 0.041 14.3 0.1 1.1 1 0 0 1 1 1 0 DoxX RRM_1 PF00076.17 KFP00148.1 - 1.8e-30 104.3 0.1 6.1e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 KFP00148.1 - 3.1e-30 104.3 1.3 9.9e-30 102.7 0.9 2.0 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_6 PF14259.1 KFP00148.1 - 1.1e-22 79.7 0.4 2e-10 40.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00148.1 - 3.3e-14 52.4 0.0 2.7e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3256 PF11644.3 KFP00148.1 - 0.16 11.4 1.3 0.25 10.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Exonuc_VII_L PF02601.10 KFP00148.1 - 6.1 5.9 9.6 8.3 5.4 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tox-PL PF15644.1 KFP00148.1 - 7.5 7.3 6.4 83 3.9 0.0 3.0 2 1 1 3 3 3 0 Papain fold toxin 1 DUF3504 PF12012.3 KFP00149.1 - 1.1e-66 223.8 0.3 3.6e-66 222.1 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) zf-FCS PF06467.9 KFP00149.1 - 6.3e-54 179.3 98.2 1.6e-09 37.2 1.7 10.8 10 1 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif Ifi-6-16 PF06140.8 KFP00150.1 - 8.6e-27 92.7 21.5 9.5e-27 92.6 14.9 1.0 1 0 0 1 1 1 1 Interferon-induced 6-16 family Y_Y_Y PF07495.8 KFP00151.1 - 2.2e-12 46.5 1.1 0.0078 15.9 0.0 5.1 5 0 0 5 5 5 3 Y_Y_Y domain Big_3_4 PF13754.1 KFP00151.1 - 3.4e-12 46.4 10.5 0.00045 20.4 0.0 5.2 4 0 0 4 4 4 3 Bacterial Ig-like domain (group 3) DUF4625 PF15418.1 KFP00151.1 - 5.6e-12 45.9 0.0 0.024 14.7 0.0 4.5 4 0 0 4 4 4 4 Domain of unknown function (DUF4625) He_PIG PF05345.7 KFP00151.1 - 1.4e-07 31.3 2.5 0.21 11.6 0.0 5.2 5 0 0 5 5 5 2 Putative Ig domain PKD PF00801.15 KFP00151.1 - 4.7e-07 29.4 21.0 0.0096 15.6 0.1 5.7 6 0 0 6 6 6 4 PKD domain Cadherin PF00028.12 KFP00151.1 - 0.00094 19.3 4.6 2.7 8.2 0.1 4.6 4 0 0 4 4 4 1 Cadherin domain fn3 PF00041.16 KFP00151.1 - 0.0018 18.3 0.6 0.14 12.2 0.0 3.5 3 0 0 3 3 3 1 Fibronectin type III domain EGF_2 PF07974.8 KFP00151.1 - 0.0035 17.4 4.4 0.0035 17.4 3.1 2.5 3 0 0 3 3 3 1 EGF-like domain Neurochondrin PF05536.6 KFP00152.1 - 7.5e-181 602.1 0.0 8.8e-181 601.9 0.0 1.0 1 0 0 1 1 1 1 Neurochondrin TF_AP-2 PF03299.9 KFP00153.1 - 1.5e-95 318.7 0.0 1.7e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 Proteasome PF00227.21 KFP00154.1 - 4.1e-35 120.7 0.0 4.5e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4653 PF15546.1 KFP00155.1 - 2.8e-81 272.3 0.0 3.2e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) Piwi PF02171.12 KFP00157.1 - 2.3e-106 355.1 0.0 3.4e-106 354.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFP00157.1 - 9.2e-40 135.0 2.8 1.7e-39 134.2 2.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFP00157.1 - 1.7e-21 75.3 0.0 3.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ATP_bind_4 PF01902.12 KFP00157.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-binding region Piwi PF02171.12 KFP00158.1 - 4.8e-110 367.2 0.0 6.7e-110 366.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFP00158.1 - 2.2e-39 133.8 1.3 3.5e-39 133.1 0.9 1.3 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFP00158.1 - 9.7e-22 76.0 0.0 1.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) DUF3465 PF11948.3 KFP00158.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) DUF2678 PF10856.3 KFP00158.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Tektin PF03148.9 KFP00159.1 - 4e-128 427.2 39.4 4.6e-128 427.0 27.3 1.0 1 0 0 1 1 1 1 Tektin family DUF1664 PF07889.7 KFP00159.1 - 0.0034 17.1 14.9 0.052 13.3 0.5 4.1 3 1 2 5 5 5 2 Protein of unknown function (DUF1664) DUF948 PF06103.6 KFP00159.1 - 0.18 11.6 9.1 4.3 7.2 0.3 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.4 KFP00159.1 - 0.19 11.6 14.8 7.3 6.5 0.4 4.2 2 2 2 4 4 4 0 Golgi transport complex subunit 5 ADP_ribosyl_GH PF03747.9 KFP00160.1 - 3.9e-52 177.8 0.0 4.9e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase C1q PF00386.16 KFP00161.1 - 1e-15 57.8 0.4 1.2e-15 57.5 0.3 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP00161.1 - 8.9e-10 37.9 31.0 2.3e-08 33.4 21.5 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) TRAPP PF04051.11 KFP00162.1 - 5e-40 136.4 0.0 5.7e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_hydro_3_C PF01915.17 KFP00163.1 - 5.8e-15 55.4 0.0 7.3e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 KFP00163.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 KFP00164.1 - 9.3e-17 60.7 0.6 1.6e-16 59.9 0.4 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.17 KFP00164.1 - 0.03 13.8 0.8 0.053 13.0 0.5 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain THRAP3_BCLAF1 PF15440.1 KFP00165.1 - 2.7e-195 650.8 115.1 2.7e-195 650.8 79.8 2.5 3 0 0 3 3 3 1 THRAP3/BCLAF1 family FAM176 PF14851.1 KFP00166.1 - 1.3e-53 180.8 0.0 1.4e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 FAM176 family Nucleoplasmin PF03066.10 KFP00166.1 - 0.019 14.4 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KFP00166.1 - 0.49 10.6 5.2 0.82 9.9 3.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NUP50 PF08911.6 KFP00166.1 - 2.6 8.4 5.6 4.5 7.7 3.9 1.3 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Pkinase PF00069.20 KFP00167.1 - 5.1e-39 133.9 0.0 7.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00167.1 - 1.4e-20 73.4 0.1 2.3e-20 72.7 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP00167.1 - 1.8e-05 23.8 0.1 4.6e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP00167.1 - 0.062 12.3 0.1 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LSM PF01423.17 KFP00168.1 - 4.6e-11 42.0 0.3 6.7e-11 41.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain Oscp1 PF10188.4 KFP00169.1 - 2.1e-58 196.9 2.6 2.9e-58 196.5 1.8 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 fn3 PF00041.16 KFP00170.1 - 4.4e-10 39.5 0.2 1.7e-08 34.4 0.1 3.0 3 0 0 3 3 3 1 Fibronectin type III domain Lep_receptor_Ig PF06328.6 KFP00170.1 - 1.1e-09 37.9 0.1 5.4e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Ig-like C2-type domain ANF_receptor PF01094.23 KFP00171.1 - 7.8e-63 212.3 0.0 1.1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 KFP00171.1 - 2.1e-54 183.2 0.7 7.2e-54 181.5 0.1 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 KFP00171.1 - 3.4e-28 97.4 1.3 2.9e-27 94.4 0.1 2.9 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFP00171.1 - 8e-21 74.3 0.0 1.4e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFP00171.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein DUF2569 PF10754.4 KFP00171.1 - 0.0043 17.2 0.6 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) RNase_Zc3h12a PF11977.3 KFP00172.1 - 7.3e-53 178.5 0.0 1.1e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH PF00642.19 KFP00172.1 - 0.014 15.0 5.0 0.03 14.0 1.9 2.3 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFP00172.1 - 0.23 11.5 7.0 0.56 10.2 4.8 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type SURF2 PF05477.6 KFP00173.1 - 0.02 14.0 2.0 0.024 13.7 1.4 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NuA4 PF09340.5 KFP00173.1 - 0.054 13.1 0.2 0.054 13.1 0.2 2.1 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Podoplanin PF05808.6 KFP00173.1 - 0.36 10.3 2.3 0.43 10.1 1.6 1.1 1 0 0 1 1 1 0 Podoplanin FHA PF00498.21 KFP00174.1 - 5.2e-14 52.1 0.1 9.4e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ax_dynein_light PF10211.4 KFP00175.1 - 2.6e-60 203.5 16.9 2.8e-60 203.4 11.7 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain IncA PF04156.9 KFP00175.1 - 0.0035 16.9 8.1 0.0042 16.7 5.6 1.2 1 0 0 1 1 1 1 IncA protein Syntaxin-6_N PF09177.6 KFP00175.1 - 0.014 15.8 7.7 0.02 15.2 5.3 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal GrpE PF01025.14 KFP00175.1 - 0.045 13.2 11.5 0.076 12.5 8.0 1.3 1 0 0 1 1 1 0 GrpE APG6 PF04111.7 KFP00175.1 - 0.045 12.7 10.0 0.046 12.7 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 KFP00175.1 - 0.046 13.4 9.8 0.065 12.9 6.8 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Packaging_FI PF14000.1 KFP00175.1 - 0.053 13.7 8.2 0.096 12.8 5.7 1.4 1 0 0 1 1 1 0 DNA packaging protein FI DUF3373 PF11853.3 KFP00175.1 - 0.11 11.0 3.0 0.11 10.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4164 PF13747.1 KFP00175.1 - 0.16 12.0 13.0 0.13 12.3 7.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Jnk-SapK_ap_N PF09744.4 KFP00175.1 - 0.44 10.5 13.9 0.69 9.8 9.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.14 KFP00175.1 - 2.8 5.6 5.5 2.7 5.7 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4337 PF14235.1 KFP00175.1 - 3.1 7.6 6.4 4 7.2 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DivIC PF04977.10 KFP00175.1 - 4.4 6.8 11.3 0.42 10.1 4.0 2.0 1 1 1 2 2 2 0 Septum formation initiator WD40_alt PF14077.1 KFP00175.1 - 4.6 6.9 7.2 2.7 7.7 0.6 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif M PF02370.11 KFP00175.1 - 5.7 7.6 10.8 0.4 11.1 2.7 2.7 2 1 0 2 2 2 0 M protein repeat NGP1NT PF08153.7 KFP00176.1 - 7.3e-49 165.0 1.2 2.1e-48 163.5 0.8 1.9 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KFP00176.1 - 4.5e-17 62.0 0.2 1.7e-13 50.5 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP00176.1 - 0.00033 19.9 0.0 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KFP00176.1 - 0.00056 19.1 0.0 0.0014 17.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFP00176.1 - 0.0031 16.9 0.0 0.75 9.2 0.0 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFP00176.1 - 0.0071 15.5 0.2 0.24 10.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 KFP00176.1 - 3 7.6 10.3 3.2 7.5 0.9 4.7 2 1 0 3 3 3 0 Dynamin family TSP_1 PF00090.14 KFP00177.1 - 0.0017 18.4 5.1 0.0017 18.4 3.5 4.1 3 1 1 4 4 4 1 Thrombospondin type 1 domain Fer4_3 PF12798.2 KFP00177.1 - 0.055 14.0 10.8 1.8 9.3 0.2 5.2 5 2 0 5 5 5 0 4Fe-4S binding domain CK2S PF15011.1 KFP00178.1 - 3.3e-22 79.0 0.0 4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Casein Kinase 2 substrate Borealin PF10512.4 KFP00179.1 - 1.3e-29 102.4 0.0 1.5e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Axin_b-cat_bind PF08833.5 KFP00179.1 - 0.19 11.4 0.5 0.52 10.0 0.0 2.0 2 1 0 2 2 2 0 Axin beta-catenin binding domain ASXH PF13919.1 KFP00180.1 - 3e-49 166.3 0.6 3e-49 166.3 0.4 2.3 2 0 0 2 2 2 1 Asx homology domain PHD_3 PF13922.1 KFP00180.1 - 1.4e-24 86.1 7.6 1.4e-24 86.1 5.3 4.0 3 0 0 3 3 3 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.8 KFP00180.1 - 3.7e-15 56.0 0.0 8.5e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain PWWP PF00855.12 KFP00182.1 - 4.5e-17 62.0 0.6 4.5e-17 62.0 0.4 1.6 2 0 0 2 2 2 1 PWWP domain DNA_methylase PF00145.12 KFP00182.1 - 4.8e-11 42.3 0.0 8.1e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase DUF2359 PF10151.4 KFP00183.1 - 3.9e-05 22.3 0.0 5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2359) SSF PF00474.12 KFP00185.1 - 5.5e-27 94.4 16.5 7e-27 94.0 11.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family FixQ PF05545.6 KFP00185.1 - 0.34 10.5 3.2 8.4 6.1 0.0 3.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ NdhL PF10716.4 KFP00185.1 - 0.61 9.8 5.8 6.5 6.6 3.8 2.6 1 1 0 1 1 1 0 NADH dehydrogenase transmembrane subunit DUF4022 PF13214.1 KFP00185.1 - 9.2 6.4 11.9 0.25 11.4 0.2 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF4022) LRR_8 PF13855.1 KFP00186.1 - 3.5e-05 23.4 0.1 7.1e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KFP00186.1 - 7e-05 22.3 0.8 0.36 11.0 0.2 2.9 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_4 PF12799.2 KFP00186.1 - 0.0051 16.3 0.7 0.22 11.1 0.6 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFP00186.1 - 0.11 12.7 2.3 1.2 9.5 0.5 3.1 3 0 0 3 3 3 0 Leucine rich repeat EGF_3 PF12947.2 KFP00186.1 - 0.21 11.5 4.5 0.4 10.6 3.1 1.5 1 0 0 1 1 1 0 EGF domain Cation_efflux PF01545.16 KFP00187.1 - 1.6e-39 135.6 2.1 1.8e-39 135.5 1.5 1.0 1 0 0 1 1 1 1 Cation efflux family Chromate_transp PF02417.10 KFP00187.1 - 0.095 12.2 5.9 0.084 12.4 0.8 2.1 2 0 0 2 2 2 0 Chromate transporter PRK PF00485.13 KFP00188.1 - 9.4e-55 185.1 0.0 1.1e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KFP00188.1 - 1.3e-07 32.4 0.1 2.3e-07 31.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFP00188.1 - 7.7e-07 29.4 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KFP00188.1 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KFP00188.1 - 9.5e-05 22.3 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 KFP00188.1 - 0.0016 17.8 0.1 0.28 10.5 0.0 2.1 2 0 0 2 2 2 2 Dephospho-CoA kinase Zeta_toxin PF06414.7 KFP00188.1 - 0.069 12.2 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DnaJ PF00226.26 KFP00189.1 - 4e-28 96.9 1.4 5.5e-28 96.4 1.0 1.2 1 0 0 1 1 1 1 DnaJ domain Mpv17_PMP22 PF04117.7 KFP00190.1 - 1.9e-26 91.5 2.0 2.7e-26 90.9 1.4 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family CPSase_L_D2 PF02786.12 KFP00191.1 - 3.4e-67 225.8 0.3 1.4e-29 102.9 0.0 3.5 2 1 1 3 3 3 3 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 KFP00191.1 - 1.1e-43 148.9 0.0 2.5e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 KFP00191.1 - 8.8e-39 132.0 0.0 6.1e-18 64.9 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KFP00191.1 - 7.9e-36 122.5 0.0 2.1e-35 121.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 KFP00191.1 - 5.4e-28 97.4 0.0 1.3e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KFP00191.1 - 1.1e-25 90.3 0.0 3.8e-25 88.5 0.0 2.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KFP00191.1 - 2.5e-17 62.6 0.1 2e-06 26.8 0.0 3.5 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_4 PF13147.1 KFP00191.1 - 8.1e-17 62.1 4.5 1.2e-15 58.3 3.1 2.5 1 1 0 1 1 1 1 Amidohydrolase ATP-grasp_4 PF13535.1 KFP00191.1 - 7.3e-14 51.9 0.5 0.0026 17.5 0.0 4.1 2 2 2 4 4 4 3 ATP-grasp domain Amidohydro_1 PF01979.15 KFP00191.1 - 1.1e-10 41.7 0.1 2.2e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Amidohydrolase family Dala_Dala_lig_C PF07478.8 KFP00191.1 - 3.2e-08 33.2 0.4 2.1e-05 24.0 0.0 3.4 3 1 1 4 4 4 2 D-ala D-ala ligase C-terminus MGS PF02142.17 KFP00191.1 - 2.5e-07 30.5 0.0 2.3e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Peptidase_C26 PF07722.8 KFP00191.1 - 3.4e-07 29.9 0.3 2.8e-05 23.6 0.2 2.6 1 1 0 1 1 1 1 Peptidase C26 Amidohydro_5 PF13594.1 KFP00191.1 - 1.6e-05 24.6 0.2 7.6e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase ATP-grasp_3 PF02655.9 KFP00191.1 - 0.00089 19.1 0.1 0.07 12.9 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 KFP00191.1 - 0.0035 16.7 0.0 0.18 11.1 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain CPSase_sm_chain PF00988.17 KFP00192.1 - 3.7e-27 94.3 0.0 4.3e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain PX PF00787.19 KFP00193.1 - 2.1e-14 53.2 0.3 6.8e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 PX domain FERM_N PF09379.5 KFP00193.1 - 0.011 15.8 0.5 0.035 14.1 0.4 2.0 1 1 0 1 1 1 0 FERM N-terminal domain FERM_M PF00373.13 KFP00193.1 - 0.013 15.6 1.3 0.058 13.5 0.2 2.5 2 1 1 3 3 3 0 FERM central domain RA PF00788.18 KFP00193.1 - 0.039 14.4 0.1 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain zf-Mss51 PF13824.1 KFP00194.1 - 0.12 12.2 0.5 0.16 11.8 0.3 1.2 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PP2C PF00481.16 KFP00195.1 - 5.7e-62 209.4 1.0 2.3e-57 194.3 0.2 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KFP00195.1 - 0.00013 21.4 0.4 0.00027 20.3 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C Pkinase PF00069.20 KFP00196.1 - 2.7e-26 92.2 1.2 4.7e-26 91.4 0.8 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00196.1 - 1.7e-25 89.5 0.7 3.2e-25 88.6 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PRESAN PF09687.5 KFP00196.1 - 0.083 12.9 8.5 0.45 10.5 5.9 2.2 1 1 0 1 1 1 0 Plasmodium RESA N-terminal BCLP PF12304.3 KFP00197.1 - 3.4e-34 117.9 1.9 3.7e-34 117.7 1.3 1.0 1 0 0 1 1 1 1 Beta-casein like protein DUF1158 PF06643.6 KFP00197.1 - 0.47 10.8 4.9 0.16 12.3 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) Clathrin PF00637.15 KFP00198.1 - 4.3e-12 45.8 32.5 0.0054 16.3 0.2 10.5 6 3 6 12 12 12 4 Region in Clathrin and VPS WD40 PF00400.27 KFP00198.1 - 3.8e-08 32.9 8.7 0.17 11.8 0.1 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFP00198.1 - 0.00034 19.5 18.5 0.0016 17.3 0.1 5.6 2 2 4 6 6 6 2 Coatomer WD associated region TPR_12 PF13424.1 KFP00198.1 - 0.032 14.1 45.7 1.5 8.8 1.1 12.2 11 3 3 14 14 14 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFP00198.1 - 0.04 13.5 31.3 18 5.0 0.0 10.9 8 3 1 9 9 9 0 TPR repeat TPR_2 PF07719.12 KFP00198.1 - 0.046 13.6 52.4 2 8.5 0.4 12.4 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFP00198.1 - 0.065 13.0 29.9 4.9 7.1 0.1 10.6 10 2 1 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP00198.1 - 0.12 12.2 29.1 2 8.4 0.0 10.6 10 2 1 11 11 11 0 Tetratricopeptide repeat fn1 PF00039.13 KFP00198.1 - 0.16 11.7 6.0 17 5.3 0.0 4.8 5 0 0 5 5 5 0 Fibronectin type I domain Mad3_BUB1_I PF08311.7 KFP00198.1 - 0.97 9.2 18.8 4 7.2 0.2 5.8 6 0 0 6 6 6 0 Mad3/BUB1 homology region 1 PID PF00640.18 KFP00199.1 - 2.9e-21 75.9 0.3 3.3e-21 75.7 0.2 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.1 KFP00199.1 - 1.3e-13 50.9 0.1 1.6e-13 50.6 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFP00199.1 - 7.5e-11 42.0 0.1 9.7e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosine-binding domain fn3 PF00041.16 KFP00200.1 - 4.8e-11 42.6 0.7 1.1e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain DUF3357 PF11837.3 KFP00200.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) zf-C2H2_jaz PF12171.3 KFP00201.1 - 5.4e-08 32.7 15.3 0.0011 19.0 0.6 4.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFP00201.1 - 5.1e-07 29.5 24.4 0.11 12.8 1.1 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP00201.1 - 5.6e-06 26.3 36.6 0.0023 18.1 2.5 6.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type CpXC PF14353.1 KFP00201.1 - 7.6e-06 25.9 11.1 0.0098 15.8 0.0 3.9 3 1 0 3 3 3 2 CpXC protein zf-BED PF02892.10 KFP00201.1 - 1.8e-05 24.4 32.0 0.24 11.2 4.0 5.6 4 1 1 5 5 5 4 BED zinc finger zf-FCS PF06467.9 KFP00201.1 - 2.3e-05 23.9 4.9 0.022 14.3 0.3 3.4 3 0 0 3 3 3 2 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 KFP00201.1 - 8.3e-05 22.6 14.1 0.42 10.7 0.3 4.4 4 0 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFP00201.1 - 0.0014 18.7 21.8 0.2 11.7 0.3 4.6 3 2 1 4 4 4 3 C2H2 type zinc-finger (2 copies) IBR PF01485.16 KFP00201.1 - 0.012 15.4 19.2 0.27 11.1 0.9 3.9 3 1 0 3 3 3 0 IBR domain GAGA PF09237.6 KFP00201.1 - 0.021 14.4 1.6 0.095 12.3 0.0 2.7 2 0 0 2 2 2 0 GAGA factor DZR PF12773.2 KFP00201.1 - 0.083 12.7 8.1 4.9 7.0 2.0 3.2 2 1 1 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KFP00201.1 - 0.1 11.8 12.5 0.62 9.3 1.1 3.5 3 1 0 3 3 3 0 zinc-ribbon domain DUF629 PF04780.7 KFP00201.1 - 4.8 5.5 11.6 0.76 8.2 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF629) zinc_ribbon_2 PF13240.1 KFP00201.1 - 5.4 6.6 14.2 7.2 6.2 0.4 4.0 4 0 0 4 4 4 0 zinc-ribbon domain ATP_bind_1 PF03029.12 KFP00202.1 - 8e-73 244.8 0.2 1.1e-72 244.3 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KFP00202.1 - 6.9e-07 28.8 0.1 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFP00202.1 - 1.6e-05 24.2 0.1 3.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KFP00202.1 - 0.0021 17.9 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.18 KFP00202.1 - 0.0024 17.2 0.1 0.0048 16.3 0.0 1.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 KFP00202.1 - 0.039 13.3 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain LSM PF01423.17 KFP00203.1 - 9.7e-15 53.8 0.4 1.3e-14 53.5 0.3 1.1 1 0 0 1 1 1 1 LSM domain Ank PF00023.25 KFP00204.1 - 8.2e-42 138.9 3.4 3.1e-09 36.1 0.2 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KFP00204.1 - 2.4e-36 123.9 1.4 2.1e-17 63.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP00204.1 - 7.7e-30 102.7 1.0 2.3e-09 37.4 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP00204.1 - 6.1e-29 99.4 4.1 3.4e-10 39.8 0.0 3.1 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP00204.1 - 1.5e-28 95.9 1.3 3.6e-08 32.8 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Mic1 PF07035.7 KFP00204.1 - 0.047 13.0 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Yae1_N PF09811.4 KFP00205.1 - 8.9e-14 50.7 38.5 3.1e+02 0.9 26.7 3.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal BTB_2 PF02214.17 KFP00206.1 - 4.7e-28 97.2 0.1 1.4e-27 95.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.26 KFP00206.1 - 1.8e-22 79.6 10.5 1.8e-22 79.6 7.3 1.8 2 0 0 2 2 2 1 Ion transport protein Shal-type PF11601.3 KFP00206.1 - 5e-14 51.5 16.5 8.5e-14 50.7 11.4 1.4 1 0 0 1 1 1 1 Shal-type voltage-gated potassium channels Ion_trans_2 PF07885.11 KFP00206.1 - 0.013 15.1 4.0 0.013 15.1 2.8 2.8 3 0 0 3 3 3 0 Ion channel PKD_channel PF08016.7 KFP00206.1 - 0.05 12.0 10.1 0.088 11.2 7.0 1.5 1 1 0 1 1 1 0 Polycystin cation channel RVT_1 PF00078.22 KFP00207.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3399 PF11879.3 KFP00208.1 - 3.5e-45 152.4 8.4 3.5e-45 152.4 5.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3399) Ion_trans_2 PF07885.11 KFP00208.1 - 0.0012 18.4 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Ion channel Tetraspannin PF00335.15 KFP00209.1 - 2.2e-32 112.1 8.7 3e-32 111.7 6.0 1.1 1 0 0 1 1 1 1 Tetraspanin family ING PF12998.2 KFP00210.1 - 2e-15 56.9 3.6 2e-15 56.9 2.5 2.1 3 0 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFP00210.1 - 9.1e-11 41.2 7.6 1.7e-10 40.3 5.3 1.5 1 0 0 1 1 1 1 PHD-finger Myosin_tail_1 PF01576.14 KFP00210.1 - 0.049 11.3 5.7 0.073 10.7 4.0 1.3 1 0 0 1 1 1 0 Myosin tail zf-RING-like PF08746.6 KFP00210.1 - 0.22 11.5 6.1 0.43 10.6 4.2 1.5 1 0 0 1 1 1 0 RING-like domain Gemini_AL3 PF01407.12 KFP00211.1 - 0.022 14.2 0.0 0.024 14.0 0.0 1.0 1 0 0 1 1 1 0 Geminivirus AL3 protein Y_phosphatase PF00102.22 KFP00213.1 - 5.4e-149 493.9 5.5 5e-89 297.6 0.7 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Carb_anhydrase PF00194.16 KFP00213.1 - 1.2e-55 188.3 0.1 2.1e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase fn3 PF00041.16 KFP00213.1 - 7.2e-13 48.4 0.1 2.7e-12 46.6 0.1 2.1 1 0 0 1 1 1 1 Fibronectin type III domain DSPc PF00782.15 KFP00213.1 - 0.00049 19.6 0.1 0.019 14.5 0.0 3.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP00213.1 - 0.0044 17.2 0.1 0.03 14.5 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Saccharop_dh PF03435.13 KFP00214.1 - 9.4e-104 347.4 0.0 1.6e-103 346.6 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 KFP00214.1 - 4.7e-48 162.9 0.0 3.2e-47 160.2 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KFP00214.1 - 1.2e-26 93.3 0.6 1.4e-25 89.9 0.0 2.7 2 1 1 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain Semialdhyde_dh PF01118.19 KFP00214.1 - 0.0005 20.3 0.4 0.0015 18.8 0.1 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFP00214.1 - 0.031 14.3 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KFP00214.1 - 0.12 12.1 0.7 1.4 8.7 0.1 2.2 1 1 1 2 2 2 0 ThiF family DUF1041 PF06292.12 KFP00215.1 - 1.7e-29 102.1 1.3 5e-29 100.5 0.9 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) PH PF00169.24 KFP00215.1 - 3.1e-06 27.3 0.0 7.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP00215.1 - 0.017 15.3 1.1 0.066 13.4 0.4 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain ATP-synt_S1 PF05827.7 KFP00216.1 - 6.5e-41 140.4 1.3 7.4e-41 140.3 0.9 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Lamp PF01299.12 KFP00216.1 - 8e-07 28.4 0.2 1.4e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) IQ PF00612.22 KFP00217.1 - 0.027 14.0 0.3 0.085 12.5 0.2 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif ETC_C1_NDUFA5 PF04716.9 KFP00218.1 - 1e-23 82.5 0.1 1.8e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Complex1_LYR PF05347.10 KFP00218.1 - 0.033 13.9 0.2 0.055 13.2 0.1 1.4 1 1 0 1 1 1 0 Complex 1 protein (LYR family) PB1-F2 PF11986.3 KFP00218.1 - 0.06 13.3 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Influenza A Proapoptotic protein Epimerase_Csub PF13950.1 KFP00218.1 - 0.085 12.8 0.3 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Complex1_LYR_1 PF13232.1 KFP00218.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Tropomodulin PF03250.9 KFP00219.1 - 4.1e-21 75.0 4.2 4.1e-21 75.0 2.9 2.2 2 0 0 2 2 2 1 Tropomodulin LRR_6 PF13516.1 KFP00219.1 - 0.023 14.7 0.0 0.11 12.6 0.0 2.2 1 0 0 1 1 1 0 Leucine Rich repeat Nop14 PF04147.7 KFP00219.1 - 0.22 9.4 34.5 0.0043 15.0 16.8 2.2 2 1 0 2 2 2 0 Nop14-like family Daxx PF03344.10 KFP00219.1 - 1.5 7.2 38.1 0.0028 16.2 14.7 2.2 2 0 0 2 2 2 0 Daxx Family WH1 PF00568.18 KFP00220.1 - 2.3e-36 123.8 0.1 3.4e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KFP00220.1 - 5.4e-17 60.8 1.7 1e-07 31.3 0.1 2.7 2 0 0 2 2 2 2 WH2 motif PBD PF00786.23 KFP00220.1 - 9e-17 61.2 0.0 2.4e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PQQ PF01011.16 KFP00220.1 - 0.058 12.9 0.0 0.3 10.6 0.0 2.2 1 0 0 1 1 1 0 PQQ enzyme repeat Glyco_hydro_56 PF01630.13 KFP00221.1 - 3.8e-135 449.9 0.5 4.5e-135 449.6 0.3 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.22 KFP00221.1 - 0.0016 18.4 1.7 0.096 12.6 0.0 2.5 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.2 KFP00221.1 - 0.036 14.1 3.6 0.036 14.1 2.5 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF TerD PF02342.13 KFP00221.1 - 0.054 12.8 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 TerD domain EGF_2 PF07974.8 KFP00221.1 - 3 8.1 10.0 1 9.6 1.5 2.5 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_56 PF01630.13 KFP00222.1 - 1.6e-141 470.8 0.3 1.9e-141 470.6 0.2 1.0 1 0 0 1 1 1 1 Hyaluronidase Arf PF00025.16 KFP00223.1 - 1.1e-38 132.2 0.0 1.3e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP00223.1 - 6.2e-13 48.4 0.0 7e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFP00223.1 - 5.7e-06 25.2 0.0 6.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 KFP00223.1 - 1.6e-05 25.3 0.0 3.5e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KFP00223.1 - 8.4e-05 21.8 0.0 9.3e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP00223.1 - 0.0003 20.2 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain 7tm_1 PF00001.16 KFP00224.1 - 7.7e-31 107.1 17.6 1.1e-30 106.6 12.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) POT1 PF02765.12 KFP00225.1 - 3.7e-32 111.2 0.0 1.5e-29 102.8 0.0 2.5 2 0 0 2 2 2 2 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 KFP00225.1 - 0.00011 22.0 1.2 7 6.5 0.0 5.0 4 1 1 5 5 5 3 OB-fold nucleic acid binding domain ANF_receptor PF01094.23 KFP00226.1 - 7.4e-100 334.1 0.0 9.4e-100 333.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFP00226.1 - 1.3e-85 286.5 15.7 2.6e-85 285.5 10.9 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFP00226.1 - 4.1e-14 52.0 10.9 8.3e-14 51.0 7.6 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFP00226.1 - 5.7e-09 35.7 0.0 1.3e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein zf-C2H2_4 PF13894.1 KFP00227.1 - 1.5e-17 62.5 53.1 0.00058 20.0 0.4 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP00227.1 - 2.1e-15 56.0 60.1 0.0022 18.2 3.3 7.7 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFP00227.1 - 1.2e-09 37.7 5.6 1.3e-08 34.4 0.1 7.0 7 1 0 7 7 7 2 C2H2-type zinc finger zf-met PF12874.2 KFP00227.1 - 2.9e-05 24.0 32.5 0.001 19.1 0.4 6.8 7 0 0 7 7 6 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP00227.1 - 3.4e-05 23.8 27.6 0.0013 18.8 0.9 5.3 5 0 0 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFP00227.1 - 6.4e-05 23.0 39.0 0.14 12.2 3.4 7.1 5 2 1 7 7 7 3 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KFP00227.1 - 8.3e-05 22.5 0.2 8.3e-05 22.5 0.2 7.1 7 0 0 7 7 7 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFP00227.1 - 0.00045 20.2 1.0 0.00045 20.2 0.7 7.4 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFP00227.1 - 0.022 15.0 0.5 0.022 15.0 0.3 10.7 12 1 0 12 12 10 0 Zinc-finger double domain CpXC PF14353.1 KFP00227.1 - 0.32 10.9 0.1 0.32 10.9 0.0 4.4 5 1 1 6 6 5 0 CpXC protein Cytochrome-c551 PF10643.4 KFP00227.1 - 5.3 6.2 9.1 1.5 8.0 0.5 2.8 3 0 0 3 3 3 0 Photosystem P840 reaction-centre cytochrome c-551 Vps39_2 PF10367.4 KFP00227.1 - 5.5 7.2 21.1 0.071 13.2 3.3 4.2 4 1 0 4 4 4 0 Vacuolar sorting protein 39 domain 2 Plexin_cytopl PF08337.7 KFP00228.1 - 2.8e-246 818.0 9.1 4.1e-246 817.4 6.3 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Sema PF01403.14 KFP00228.1 - 1e-36 126.4 11.8 1.2e-36 126.1 4.5 2.2 1 1 1 2 2 2 2 Sema domain TIG PF01833.19 KFP00228.1 - 3.9e-31 106.8 16.8 1.1e-10 41.3 0.1 5.6 6 0 0 6 6 6 4 IPT/TIG domain PSI PF01437.20 KFP00228.1 - 2.7e-13 49.8 54.1 2.4e-10 40.4 11.3 3.6 3 0 0 3 3 3 3 Plexin repeat RasGAP PF00616.14 KFP00228.1 - 4.8e-06 26.3 0.0 0.00028 20.6 0.0 3.0 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Pkinase PF00069.20 KFP00229.1 - 6e-64 215.6 0.1 7e-64 215.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00229.1 - 1.2e-26 93.3 0.1 1.5e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFP00229.1 - 9.5e-06 24.8 0.1 1.4e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP00229.1 - 0.0017 18.1 0.0 0.01 15.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFP00229.1 - 0.0022 17.3 0.0 0.0044 16.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFP00229.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3890 PF13029.1 KFP00229.1 - 0.14 12.2 1.6 0.19 11.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) Pkinase PF00069.20 KFP00230.1 - 3.2e-67 226.4 0.2 3.9e-67 226.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00230.1 - 1.2e-27 96.6 0.1 1.6e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFP00230.1 - 0.00012 21.4 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFP00230.1 - 0.00021 20.3 0.1 0.00079 18.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KFP00230.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFP00230.1 - 0.0021 17.1 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fz PF01392.17 KFP00231.1 - 2.8e-29 101.8 8.6 2.8e-29 101.8 6.0 1.9 3 0 0 3 3 3 1 Fz domain DUF1182 PF06681.8 KFP00231.1 - 0.052 12.7 0.5 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) Hist_deacetyl PF00850.14 KFP00232.1 - 2.4e-87 293.1 0.0 3.1e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Spc97_Spc98 PF04130.8 KFP00233.1 - 5.1e-122 407.9 9.7 1.6e-121 406.2 6.7 1.8 1 1 0 1 1 1 1 Spc97 / Spc98 family DUF4573 PF15140.1 KFP00233.1 - 0.00012 21.7 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) UPF0061 PF02696.9 KFP00234.1 - 2.2e-98 329.7 0.2 4.7e-89 298.9 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family TraB PF01963.12 KFP00235.1 - 4.4e-46 157.4 0.0 8.2e-46 156.5 0.0 1.4 1 1 1 2 2 2 1 TraB family Glyco_tran_WecB PF03808.8 KFP00235.1 - 0.1 12.0 0.1 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family RRM_3 PF08777.6 KFP00235.1 - 0.11 12.3 0.1 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Tetraspannin PF00335.15 KFP00236.1 - 0.0042 16.3 4.1 0.0042 16.3 2.9 1.0 1 0 0 1 1 1 1 Tetraspanin family TMEM238 PF15125.1 KFP00236.1 - 0.12 12.3 3.0 0.13 12.1 2.1 1.1 1 0 0 1 1 1 0 TMEM238 protein family Innexin PF00876.13 KFP00237.1 - 7.7e-09 35.1 1.9 1.6e-08 34.0 0.6 2.0 1 1 1 2 2 2 1 Innexin AAA_12 PF13087.1 KFP00238.1 - 1.5e-43 148.5 0.0 3.2e-43 147.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFP00238.1 - 1.8e-38 132.4 0.0 2.5e-19 69.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KFP00238.1 - 4.6e-13 49.2 0.0 1.2e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain S1-like PF14444.1 KFP00238.1 - 1.2e-10 40.9 1.2 0.0016 18.0 0.0 3.9 3 0 0 3 3 3 2 S1-like AAA_19 PF13245.1 KFP00238.1 - 5.2e-09 35.7 0.0 1.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFP00238.1 - 0.00027 21.0 0.0 0.00094 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KFP00238.1 - 0.00031 20.3 0.1 0.42 10.0 0.0 3.1 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KFP00238.1 - 0.0027 17.5 0.0 0.0073 16.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFP00238.1 - 0.0045 16.4 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C PF13361.1 KFP00238.1 - 0.0067 15.9 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KFP00238.1 - 0.013 14.8 0.0 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KFP00238.1 - 0.014 14.6 0.0 0.17 11.0 0.0 2.2 1 1 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 KFP00238.1 - 0.036 14.2 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 KFP00238.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 KFP00238.1 - 0.14 11.1 0.0 12 4.6 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase IL17_R_N PF15037.1 KFP00240.1 - 2.4e-47 161.8 10.2 3.3e-47 161.4 7.1 1.3 1 0 0 1 1 1 1 Interleukin-17 receptor extracellular region KSHV_K1 PF11049.3 KFP00240.1 - 1.2 9.1 4.4 4 7.4 0.1 3.0 4 0 0 4 4 4 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus DUF3049 PF11250.3 KFP00241.1 - 0.17 11.6 0.8 2.3 8.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) EGF_CA PF07645.10 KFP00242.1 - 8.9e-15 54.4 27.0 1.8e-10 40.6 8.2 7.2 4 2 2 6 6 6 2 Calcium-binding EGF domain DUF3456 PF11938.3 KFP00242.1 - 6.8e-11 42.3 5.8 1.8e-06 28.0 2.0 3.1 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP VSP PF03302.8 KFP00242.1 - 0.0028 16.3 63.1 0.22 10.1 21.0 3.2 1 1 1 2 2 2 2 Giardia variant-specific surface protein EGF PF00008.22 KFP00242.1 - 0.0038 17.1 2.3 0.0038 17.1 1.6 6.3 7 2 2 9 9 9 3 EGF-like domain PmrD PF11183.3 KFP00242.1 - 0.022 14.5 0.3 0.056 13.2 0.2 1.7 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD EGF_MSP1_1 PF12946.2 KFP00242.1 - 0.029 14.1 4.2 0.029 14.1 2.9 5.1 4 1 1 5 5 5 0 MSP1 EGF domain 1 hEGF PF12661.2 KFP00242.1 - 3.6 7.8 19.5 0.4 10.8 0.9 5.9 6 1 0 6 6 6 0 Human growth factor-like EGF Glyco_transf_22 PF03901.12 KFP00243.1 - 2.5e-44 151.9 30.5 3.1e-44 151.6 21.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-BED PF02892.10 KFP00244.1 - 2.8e-59 196.6 27.3 1.6e-15 56.5 0.2 4.6 4 0 0 4 4 4 4 BED zinc finger Dimer_Tnp_hAT PF05699.9 KFP00244.1 - 1.2e-10 40.8 3.8 4.2e-10 39.0 0.4 3.3 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region PyrI_C PF02748.10 KFP00244.1 - 0.013 14.8 5.3 6 6.3 0.0 4.1 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4413 PF14372.1 KFP00244.1 - 0.058 13.3 1.2 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) zf-HC5HC2H_2 PF13832.1 KFP00245.1 - 2e-39 133.9 4.5 2e-39 133.9 3.1 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 KFP00245.1 - 7.4e-36 123.8 2.6 7.4e-36 123.8 1.8 2.9 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 KFP00245.1 - 2.4e-27 94.9 3.2 2.4e-27 94.9 2.2 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 KFP00245.1 - 9.5e-25 86.3 0.4 2.6e-24 84.9 0.3 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.12 KFP00245.1 - 1.3e-14 54.1 0.0 5.6e-14 52.0 0.0 2.2 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.1 KFP00245.1 - 1.8e-13 49.5 4.3 1.8e-13 49.5 3.0 2.8 2 1 0 2 2 2 1 PHD-finger PHD PF00628.24 KFP00245.1 - 7.6e-07 28.7 28.2 1.1e-05 25.0 9.5 2.9 2 0 0 2 2 2 2 PHD-finger DNA_topoisoIV PF00521.15 KFP00245.1 - 0.043 12.6 4.6 0.086 11.6 3.2 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF3439 PF11921.3 KFP00245.1 - 0.061 13.0 1.4 0.21 11.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) AAA_23 PF13476.1 KFP00245.1 - 2.4 8.4 8.6 0.49 10.6 0.3 2.9 3 0 0 3 3 3 0 AAA domain TAFA PF12020.3 KFP00246.1 - 1.5e-28 98.7 6.7 1.7e-28 98.5 4.6 1.0 1 0 0 1 1 1 1 TAFA family zf-CGNR PF11706.3 KFP00246.1 - 0.1 12.1 3.7 1.3 8.6 0.2 2.6 2 1 0 2 2 2 0 CGNR zinc finger Yae1_N PF09811.4 KFP00247.1 - 4.4e-15 54.9 50.0 4e-05 23.0 8.3 4.3 1 1 1 2 2 2 1 Essential protein Yae1, N terminal RabGAP-TBC PF00566.13 KFP00248.1 - 4.3e-49 166.9 2.0 6.9e-49 166.2 1.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DAGK_cat PF00781.19 KFP00249.1 - 5.4e-17 61.4 0.0 9.8e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RVT_1 PF00078.22 KFP00250.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.19 KFP00251.1 - 4.8e-26 90.6 0.1 6.8e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFP00251.1 - 1.1e-06 28.5 0.7 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFP00251.1 - 0.0028 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A GTSE1_N PF15259.1 KFP00252.1 - 1.1e-48 164.7 0.5 1.1e-48 164.7 0.3 3.3 3 0 0 3 3 3 1 G-2 and S-phase expressed 1 CGI-121 PF08617.5 KFP00253.1 - 1.4e-43 148.3 1.5 1.6e-43 148.1 1.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Exonuc_VII_S PF02609.11 KFP00253.1 - 0.11 12.2 0.4 0.22 11.3 0.3 1.5 1 0 0 1 1 1 0 Exonuclease VII small subunit DUF4284 PF14112.1 KFP00253.1 - 0.13 12.7 0.1 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) DIE2_ALG10 PF04922.7 KFP00254.1 - 5.2e-138 460.2 32.5 7.2e-138 459.7 22.5 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Copine PF07002.11 KFP00255.1 - 4.3e-60 201.6 0.1 6.8e-60 201.0 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 KFP00255.1 - 8.6e-28 96.0 0.8 2.3e-15 56.1 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFP00255.1 - 9.7e-10 38.6 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Glyco_hydro_31 PF01055.21 KFP00256.1 - 2.5e-160 534.1 1.2 3.1e-160 533.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFP00256.1 - 6.4e-06 25.9 0.1 2.7e-05 23.9 0.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like ABC_membrane_2 PF06472.10 KFP00257.1 - 2.7e-106 354.7 5.1 3.6e-106 354.4 3.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFP00257.1 - 1.6e-18 67.3 0.0 3.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFP00257.1 - 0.00029 20.9 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFP00257.1 - 0.0029 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KFP00257.1 - 0.0051 17.1 1.8 0.0085 16.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 KFP00257.1 - 0.02 14.1 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFP00257.1 - 0.034 14.1 0.1 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 KFP00257.1 - 0.04 12.5 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Adeno_IVa2 PF02456.10 KFP00257.1 - 0.05 12.2 0.0 0.079 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein MutS_V PF00488.16 KFP00257.1 - 0.076 12.4 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 MutS domain V Sugar_tr PF00083.19 KFP00258.1 - 6.9e-91 305.0 15.0 5.4e-68 229.6 1.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFP00258.1 - 3.1e-15 55.7 24.1 4e-12 45.5 9.2 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFP00258.1 - 0.00026 19.5 1.6 0.00026 19.5 1.1 2.1 2 1 0 2 2 2 1 MFS/sugar transport protein Ral PF11058.3 KFP00258.1 - 0.048 13.0 0.9 0.089 12.1 0.6 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral Pkinase PF00069.20 KFP00259.1 - 1.2e-43 149.1 0.0 2.9e-43 147.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00259.1 - 5.7e-40 137.0 0.0 1.8e-39 135.4 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.1 KFP00259.1 - 9.8e-30 102.1 38.3 5.2e-09 35.7 4.9 6.1 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFP00259.1 - 6.4e-27 92.6 45.4 7.8e-09 34.9 0.4 8.8 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) Miro PF08477.8 KFP00259.1 - 1.5e-26 93.2 0.0 4.3e-26 91.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFP00259.1 - 8.1e-16 57.8 0.0 2e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Ras family LRR_1 PF00560.28 KFP00259.1 - 6.8e-10 37.5 47.0 0.2 11.8 0.0 13.2 13 0 0 13 13 12 4 Leucine Rich Repeat Arf PF00025.16 KFP00259.1 - 1.4e-07 30.9 1.1 2.4e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family LRR_7 PF13504.1 KFP00259.1 - 7.2e-06 25.3 35.0 1.6 9.2 0.1 12.0 12 0 0 12 12 10 2 Leucine rich repeat Ank_2 PF12796.2 KFP00259.1 - 0.00015 22.0 0.9 0.0017 18.6 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Gtr1_RagA PF04670.7 KFP00259.1 - 0.00031 19.9 0.0 0.00068 18.8 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 KFP00259.1 - 0.0028 17.9 0.2 0.0092 16.2 0.1 1.9 1 0 0 1 1 1 1 ABC transporter PduV-EutP PF10662.4 KFP00259.1 - 0.0032 16.9 0.7 0.0092 15.4 0.5 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 KFP00259.1 - 0.0037 16.2 0.0 0.0077 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 KFP00259.1 - 0.0047 17.7 0.8 0.022 15.5 0.0 2.7 3 0 0 3 3 1 1 AAA domain Ank PF00023.25 KFP00259.1 - 0.0059 16.3 1.2 19 5.2 0.0 4.3 4 0 0 4 4 3 0 Ankyrin repeat AAA_22 PF13401.1 KFP00259.1 - 0.0067 16.5 0.0 0.036 14.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KFP00259.1 - 0.007 16.3 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 1 1 50S ribosome-binding GTPase Arm PF00514.18 KFP00259.1 - 0.011 15.5 3.1 0.063 13.1 0.1 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TrwB_AAD_bind PF10412.4 KFP00259.1 - 0.014 14.0 0.1 0.032 12.8 0.1 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain LRR_6 PF13516.1 KFP00259.1 - 0.017 15.1 45.6 3 8.1 0.4 12.1 8 2 4 12 12 11 0 Leucine Rich repeat MobB PF03205.9 KFP00259.1 - 0.018 14.7 0.3 0.05 13.2 0.2 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KFP00259.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 KFP00259.1 - 0.022 14.4 1.9 0.05 13.2 0.3 2.3 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 KFP00259.1 - 0.026 13.9 0.3 0.052 12.9 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KFP00259.1 - 0.036 14.3 0.0 0.16 12.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain Kdo PF06293.9 KFP00259.1 - 0.065 12.2 0.1 0.17 10.9 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_29 PF13555.1 KFP00259.1 - 0.079 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KFP00259.1 - 0.096 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFP00259.1 - 0.2 11.0 0.2 0.51 9.7 0.1 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 KFP00259.1 - 0.3 10.4 0.1 1.1 8.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain PQQ_2 PF13360.1 KFP00259.1 - 0.98 8.8 0.0 1.7 8.0 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain AAA_23 PF13476.1 KFP00259.1 - 7.5 6.8 9.7 0.64 10.3 0.0 3.5 4 0 0 4 4 3 0 AAA domain COPIIcoated_ERV PF07970.7 KFP00260.1 - 5.9e-47 160.1 0.3 8.5e-47 159.6 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFP00260.1 - 2.8e-20 72.0 0.3 7.4e-20 70.7 0.2 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pyr_redox_dim PF02852.17 KFP00261.1 - 1.7e-41 140.7 0.7 4.9e-41 139.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFP00261.1 - 9.6e-40 136.6 9.8 3.5e-39 134.7 6.8 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFP00261.1 - 1.2e-18 67.2 6.8 5.7e-17 61.8 0.7 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFP00261.1 - 5.4e-10 39.6 1.1 3.8e-05 23.8 0.8 2.6 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFP00261.1 - 1.1e-09 37.6 2.9 6.1e-07 28.6 0.3 3.1 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 KFP00261.1 - 6.9e-09 35.2 0.5 6.9e-09 35.2 0.3 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFP00261.1 - 2.1e-07 30.8 2.5 0.00014 21.7 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFP00261.1 - 4.2e-06 25.8 10.1 8.3e-06 24.9 2.7 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KFP00261.1 - 2.3e-05 23.6 0.2 2.3e-05 23.6 0.1 2.1 1 1 1 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KFP00261.1 - 4.8e-05 22.5 3.9 0.01 14.9 0.1 3.3 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 KFP00261.1 - 9.8e-05 21.4 1.8 0.15 10.9 0.2 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KFP00261.1 - 0.0001 20.9 11.2 0.0014 17.1 0.3 3.7 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 KFP00261.1 - 0.00056 19.5 3.9 0.074 12.6 0.1 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KFP00261.1 - 0.0097 15.2 5.2 1.3 8.3 0.1 3.4 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KFP00261.1 - 0.02 14.5 4.7 0.48 10.0 0.5 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KFP00261.1 - 0.038 12.9 13.2 0.11 11.4 0.4 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase UPF0227 PF05728.7 KFP00261.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GFO_IDH_MocA PF01408.17 KFP00261.1 - 0.54 10.7 3.1 74 3.8 0.1 3.7 4 0 0 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold Sulfate_transp PF00916.15 KFP00262.1 - 2.2e-70 236.8 12.7 2.2e-70 236.8 8.8 1.6 2 0 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 KFP00262.1 - 2.9e-34 116.9 0.1 5.2e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain Sulfate_tra_GLY PF13792.1 KFP00262.1 - 1.9e-28 97.9 3.4 1.9e-28 97.9 2.4 2.8 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif zf-C3HC4_3 PF13920.1 KFP00263.1 - 0.00024 20.6 7.5 0.00055 19.5 5.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP00263.1 - 0.00067 19.6 9.3 0.0017 18.3 6.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP00263.1 - 0.001 18.6 8.7 0.0022 17.6 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP00263.1 - 0.0018 17.9 7.8 0.0038 16.9 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP00263.1 - 0.03 14.1 7.9 0.069 12.9 5.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 KFP00263.1 - 0.047 13.1 6.6 0.1 12.1 4.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 KFP00263.1 - 0.052 13.3 7.5 0.2 11.5 5.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 KFP00263.1 - 1.4 8.5 8.2 3.9 7.1 5.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_4 PF07975.7 KFP00263.1 - 5.8 6.9 11.6 5.2 7.1 6.4 2.3 2 1 0 2 2 2 0 TFIIH C1-like domain Bap31 PF05529.7 KFP00264.1 - 7.5e-43 146.2 22.8 1.7e-40 138.5 15.8 2.5 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like Presenilin PF01080.12 KFP00264.1 - 0.0012 17.7 0.8 0.0015 17.4 0.6 1.1 1 0 0 1 1 1 1 Presenilin DUF1664 PF07889.7 KFP00264.1 - 0.0017 18.1 2.9 0.0017 18.1 2.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) AATF-Che1 PF13339.1 KFP00264.1 - 0.0024 18.0 8.3 0.0041 17.2 5.7 1.4 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor HALZ PF02183.13 KFP00264.1 - 0.0029 17.2 12.4 0.029 14.0 2.3 3.3 3 0 0 3 3 3 1 Homeobox associated leucine zipper AAA_13 PF13166.1 KFP00264.1 - 0.0056 15.2 7.7 0.0072 14.8 5.3 1.0 1 0 0 1 1 1 1 AAA domain WEMBL PF05701.6 KFP00264.1 - 0.0064 15.0 14.4 0.0079 14.7 10.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light MscS_porin PF12795.2 KFP00264.1 - 0.0079 15.5 11.8 0.01 15.2 8.2 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF2317 PF10079.4 KFP00264.1 - 0.014 14.0 4.9 0.017 13.7 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF948 PF06103.6 KFP00264.1 - 0.016 15.0 10.6 0.31 10.9 0.3 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.3 KFP00264.1 - 0.028 14.3 13.4 0.041 13.7 9.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KFP00264.1 - 0.039 13.0 14.6 0.056 12.4 10.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Laminin_II PF06009.7 KFP00264.1 - 0.039 13.6 2.1 0.039 13.6 1.5 2.1 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.1 KFP00264.1 - 0.043 13.0 15.5 0.067 12.3 10.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Apolipoprotein PF01442.13 KFP00264.1 - 0.047 13.1 12.3 0.066 12.7 8.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CCDC155 PF14662.1 KFP00264.1 - 0.065 12.8 14.4 0.089 12.3 10.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 KFP00264.1 - 0.077 13.3 16.0 0.041 14.2 5.0 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF972) PilJ PF13675.1 KFP00264.1 - 0.082 13.2 0.6 0.082 13.2 0.4 2.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Tropomyosin_1 PF12718.2 KFP00264.1 - 0.086 12.6 17.7 0.12 12.1 12.2 1.1 1 0 0 1 1 1 0 Tropomyosin like CENP-K PF11802.3 KFP00264.1 - 0.14 11.3 6.9 0.2 10.8 4.8 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Syntaxin_2 PF14523.1 KFP00264.1 - 0.16 12.0 8.4 0.33 10.9 5.8 1.6 1 1 0 1 1 1 0 Syntaxin-like protein Microtub_assoc PF07989.6 KFP00264.1 - 0.17 11.7 7.7 0.33 10.8 5.1 1.7 1 1 0 1 1 1 0 Microtubule associated DUF3450 PF11932.3 KFP00264.1 - 0.19 10.9 7.6 0.31 10.2 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 KFP00264.1 - 0.2 10.8 0.7 0.33 10.1 0.5 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Uds1 PF15456.1 KFP00264.1 - 0.23 11.4 11.9 0.3 11.0 7.7 1.6 1 1 0 1 1 1 0 Up-regulated During Septation Bul1_C PF04426.7 KFP00264.1 - 0.23 10.5 4.3 0.3 10.2 3.0 1.1 1 0 0 1 1 1 0 Bul1 C terminus IncA PF04156.9 KFP00264.1 - 0.27 10.8 15.1 0.49 9.9 10.5 1.5 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 KFP00264.1 - 0.27 9.5 9.1 0.34 9.2 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cep57_CLD_2 PF14197.1 KFP00264.1 - 0.29 11.0 11.7 0.15 11.9 5.9 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Cluap1 PF10234.4 KFP00264.1 - 0.42 9.7 10.6 0.6 9.2 7.3 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF3810 PF12725.2 KFP00264.1 - 0.43 9.4 6.1 0.71 8.7 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DivIVA PF05103.8 KFP00264.1 - 0.5 10.4 12.5 0.91 9.5 8.7 1.5 1 0 0 1 1 1 0 DivIVA protein Transposase_22 PF02994.9 KFP00264.1 - 0.57 8.6 9.7 0.74 8.2 6.7 1.1 1 0 0 1 1 1 0 L1 transposable element DUF724 PF05266.9 KFP00264.1 - 0.64 9.6 10.4 0.98 9.0 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.4 KFP00264.1 - 0.77 8.6 8.3 0.85 8.4 5.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KFP00264.1 - 0.79 9.3 11.7 1.3 8.6 8.1 1.3 1 0 0 1 1 1 0 Mnd1 family IFP_35_N PF07334.8 KFP00264.1 - 1.2 9.1 6.6 0.6 10.1 2.6 1.9 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4140 PF13600.1 KFP00264.1 - 1.3 9.5 9.2 0.73 10.3 2.6 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tho2 PF11262.3 KFP00264.1 - 1.5 7.7 6.7 2.2 7.2 4.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Sec2p PF06428.6 KFP00264.1 - 2.1 8.2 17.1 4.4 7.2 1.4 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Seryl_tRNA_N PF02403.17 KFP00264.1 - 2.8 7.9 14.7 6.4 6.8 10.1 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain WXG100 PF06013.7 KFP00264.1 - 3.6 7.6 7.0 8.9 6.3 3.3 2.5 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Vfa1 PF08432.5 KFP00264.1 - 4.5 7.2 12.0 6.7 6.6 8.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 KFP00264.1 - 6.1 5.7 16.0 0.017 14.1 4.5 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 KFP00264.1 - 8.4 6.3 8.6 13 5.7 1.2 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Dus PF01207.12 KFP00265.1 - 2.1e-72 243.6 0.1 2.5e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 KFP00265.1 - 0.00011 21.3 0.0 0.00021 20.4 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 KFP00265.1 - 0.0007 18.9 0.0 0.0026 17.0 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 KFP00265.1 - 0.0056 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI ThiG PF05690.9 KFP00265.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 KFP00265.1 - 0.091 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) COG5 PF10392.4 KFP00266.1 - 1.2e-30 106.1 4.5 1.2e-30 106.1 3.1 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 KFP00266.1 - 4.2e-09 36.1 0.8 4.2e-09 36.1 0.5 3.2 5 0 0 5 5 5 1 Vps51/Vps67 COG2 PF06148.6 KFP00266.1 - 0.00014 21.7 1.2 0.00014 21.7 0.8 3.3 5 0 0 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 HrpB7 PF09486.5 KFP00266.1 - 0.027 14.4 3.7 0.089 12.7 1.1 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Gp58 PF07902.6 KFP00266.1 - 0.042 12.0 1.5 0.067 11.4 1.0 1.2 1 0 0 1 1 1 0 gp58-like protein DUF2450 PF10475.4 KFP00266.1 - 0.051 12.4 8.3 0.023 13.5 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DUF4461 PF14688.1 KFP00266.1 - 0.077 12.3 3.0 0.19 11.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4461) 7tm_1 PF00001.16 KFP00267.1 - 1.4e-25 89.9 21.0 2.2e-25 89.2 14.6 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.6 KFP00267.1 - 0.78 8.4 15.5 0.11 11.3 7.4 2.0 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin AXH PF08517.7 KFP00268.1 - 4e-43 146.2 0.0 8.7e-43 145.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) HMG_box PF00505.14 KFP00268.1 - 9.5e-15 54.6 0.8 1.8e-14 53.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP00268.1 - 4.5e-09 36.5 2.0 9.3e-09 35.5 1.4 1.5 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KFP00268.1 - 0.015 14.6 0.3 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 CAF-1_p150 PF11600.3 KFP00268.1 - 0.71 9.2 4.0 1.4 8.2 2.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal cNMP_binding PF00027.24 KFP00269.1 - 1e-40 137.4 0.1 6.9e-22 77.0 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PI3Ka PF00613.15 KFP00270.1 - 5e-63 211.6 1.4 5e-63 211.6 1.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFP00270.1 - 5.4e-54 183.1 0.3 1.1e-53 182.1 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.13 KFP00270.1 - 3.9e-29 100.7 1.3 8.5e-27 93.2 0.0 3.1 3 0 0 3 3 3 2 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 KFP00270.1 - 2.4e-28 98.7 0.5 7e-28 97.1 0.1 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 COX5A PF02284.11 KFP00270.1 - 0.089 12.7 0.2 0.67 9.9 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va NAPRTase PF04095.11 KFP00271.1 - 8.6e-80 267.5 0.0 1.2e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family MARVEL PF01284.18 KFP00272.1 - 8.2e-34 116.4 15.2 1e-33 116.1 10.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4418 PF14387.1 KFP00272.1 - 0.016 14.9 3.8 0.032 13.9 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) SCA7 PF08313.7 KFP00273.1 - 5.6e-28 96.3 4.9 6.4e-28 96.1 2.4 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF3505 PF12013.3 KFP00273.1 - 0.063 13.5 2.1 0.37 11.0 1.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) EF-hand_6 PF13405.1 KFP00274.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain RINT1_TIP1 PF04437.8 KFP00275.1 - 8.3e-159 529.2 13.1 8.3e-159 529.2 9.1 2.1 2 0 0 2 2 2 2 RINT-1 / TIP-1 family TruD PF01142.13 KFP00276.1 - 6.9e-68 229.0 0.0 1.2e-65 221.6 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) R3H PF01424.17 KFP00276.1 - 0.039 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 R3H domain XPG_I_2 PF12813.2 KFP00276.1 - 0.067 12.6 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Pkinase PF00069.20 KFP00277.1 - 2.8e-34 118.4 6.9 1.4e-22 80.1 0.3 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00277.1 - 3.7e-13 49.1 0.1 1.2e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase SET PF00856.23 KFP00278.1 - 5.4e-11 43.0 0.1 5.4e-11 43.0 0.1 4.0 3 2 0 3 3 3 1 SET domain PHD PF00628.24 KFP00278.1 - 1.5e-09 37.3 12.0 3.6e-09 36.1 8.3 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFP00278.1 - 0.005 16.1 8.2 0.011 15.0 5.7 1.6 1 0 0 1 1 1 1 PHD-finger ORC5_C PF14630.1 KFP00279.1 - 3e-78 263.0 0.0 4.5e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KFP00279.1 - 1.7e-09 37.8 0.0 3.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFP00279.1 - 8.2e-09 35.7 0.2 1.6e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFP00279.1 - 0.00047 19.9 0.1 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase Kinesin PF00225.18 KFP00279.1 - 0.0013 17.5 0.3 0.0028 16.3 0.2 1.5 1 1 0 1 1 1 1 Kinesin motor domain AAA_14 PF13173.1 KFP00279.1 - 0.0016 18.3 0.8 0.05 13.5 0.5 2.4 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.9 KFP00279.1 - 0.022 13.7 0.0 0.065 12.1 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.24 KFP00279.1 - 0.062 13.4 0.0 0.22 11.6 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFP00279.1 - 0.089 13.6 0.0 0.26 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KFP00279.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sulfate_transp PF00916.15 KFP00280.1 - 6.8e-71 238.5 16.7 1.9e-70 237.0 11.4 1.9 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFP00280.1 - 2.8e-30 103.8 4.0 2.8e-30 103.8 2.7 3.5 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFP00280.1 - 2e-27 94.8 0.0 3.6e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain AAA PF00004.24 KFP00281.1 - 5.5e-41 139.8 0.0 2.8e-40 137.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP00281.1 - 7.4e-06 26.1 0.0 0.00077 19.6 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KFP00281.1 - 0.00016 21.3 0.1 0.0013 18.5 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFP00281.1 - 0.0018 18.3 0.0 0.007 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KFP00281.1 - 0.0018 19.0 0.1 0.0059 17.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFP00281.1 - 0.0029 17.5 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFP00281.1 - 0.0046 15.9 0.0 0.015 14.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KFP00281.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFP00281.1 - 0.0059 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KFP00281.1 - 0.0099 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFP00281.1 - 0.01 14.8 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KFP00281.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KFP00281.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KFP00281.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 KFP00281.1 - 0.027 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFP00281.1 - 0.036 14.3 0.1 0.093 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mistic PF11458.3 KFP00281.1 - 0.044 14.1 1.3 0.16 12.4 0.6 2.0 2 0 0 2 2 2 0 Membrane-integrating protein Mistic Mg_chelatase PF01078.16 KFP00281.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KFP00281.1 - 0.069 11.8 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KFP00281.1 - 0.081 13.1 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.1 KFP00281.1 - 0.084 12.2 0.0 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KFP00281.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Myb_DNA-binding PF00249.26 KFP00282.1 - 1.4e-17 63.5 0.2 4.3e-10 39.4 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DnaJ PF00226.26 KFP00282.1 - 8.7e-17 60.6 0.1 8.7e-17 60.6 0.1 2.8 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.1 KFP00282.1 - 1.8e-08 34.3 10.0 6.6e-06 26.1 0.1 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain Peptidase_M16 PF00675.15 KFP00283.1 - 1e-57 194.0 0.2 1.5e-57 193.5 0.1 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFP00283.1 - 3.6e-42 144.1 0.0 2.6e-41 141.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Lactamase_B_2 PF12706.2 KFP00284.1 - 1.3e-40 139.0 0.1 1.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFP00284.1 - 1.6e-14 53.9 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFP00284.1 - 0.003 17.2 0.3 0.15 11.6 0.2 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Arm_2 PF04826.8 KFP00285.1 - 1.4e-69 233.9 7.6 1.6e-69 233.8 5.2 1.0 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.18 KFP00285.1 - 2.6e-08 33.3 3.1 0.0042 16.8 0.0 3.6 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP00285.1 - 4.5e-06 26.8 0.0 0.012 15.9 0.0 2.3 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 KFP00285.1 - 0.0014 18.5 0.1 1.4 9.1 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat PUL PF08324.6 KFP00285.1 - 0.0015 17.3 3.1 0.0039 16.0 1.4 1.9 1 1 1 2 2 2 1 PUL domain V-ATPase_H_N PF03224.9 KFP00285.1 - 0.053 12.6 1.3 0.084 11.9 0.9 1.4 1 1 0 1 1 1 0 V-ATPase subunit H Atx10homo_assoc PF09759.4 KFP00285.1 - 0.15 11.8 1.0 1 9.1 0.6 2.2 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain LRR_6 PF13516.1 KFP00286.1 - 1e-31 105.3 27.3 0.023 14.7 0.3 14.8 15 0 0 15 15 15 9 Leucine Rich repeat LRR_4 PF12799.2 KFP00286.1 - 4.9e-19 67.5 9.1 0.002 17.7 0.2 8.6 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP00286.1 - 5.5e-14 51.6 15.9 0.0017 18.0 0.5 7.4 5 3 3 8 8 8 4 Leucine rich repeat LRR_1 PF00560.28 KFP00286.1 - 7.8e-14 49.5 22.3 2.6 8.4 0.0 14.1 10 5 3 13 13 13 4 Leucine Rich Repeat LRR_7 PF13504.1 KFP00286.1 - 2.3e-08 32.9 27.4 2.5 8.7 0.1 12.5 14 1 0 14 14 14 3 Leucine rich repeat F-box-like PF12937.2 KFP00286.1 - 3.1e-06 26.8 1.1 9.7e-06 25.2 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFP00286.1 - 0.00012 21.6 0.0 0.00048 19.6 0.0 2.2 1 0 0 1 1 1 1 F-box domain Ste50p-SAM PF09235.5 KFP00286.1 - 0.022 14.7 11.4 8.7 6.4 0.0 5.7 6 0 0 6 6 6 0 Ste50p, sterile alpha motif LRR_8 PF13855.1 KFP00287.1 - 7.1e-34 115.3 33.5 4e-13 48.9 1.6 4.6 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KFP00287.1 - 7.5e-17 60.5 24.5 1.1e-06 28.1 3.7 5.4 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP00287.1 - 3.4e-13 49.4 0.2 7.4e-07 28.9 0.1 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFP00287.1 - 1.1e-09 38.0 4.1 8.3e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 KFP00287.1 - 1.9e-09 36.2 23.0 0.16 12.0 0.8 8.3 9 0 0 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.1 KFP00287.1 - 4.7e-07 29.2 14.0 1.7 8.9 0.8 6.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 KFP00287.1 - 0.013 15.5 21.8 1.4 9.4 0.7 7.4 8 0 0 8 8 8 0 Leucine rich repeat DUF4098 PF13345.1 KFP00288.1 - 1.4e-15 56.9 15.1 1.7e-05 24.6 1.2 4.2 3 2 0 4 4 4 3 Domain of unknown function (DUF4098) DUF4097 PF13349.1 KFP00288.1 - 0.0043 16.6 12.6 0.53 9.8 0.4 3.7 2 2 0 2 2 2 2 Domain of unknown function (DUF4097) DUF2807 PF10988.3 KFP00288.1 - 0.0053 16.3 6.6 0.0098 15.4 1.2 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2807) BON PF04972.12 KFP00288.1 - 0.0092 15.7 0.7 54 3.6 0.0 4.5 4 1 1 5 5 5 0 BON domain HMA PF00403.21 KFP00288.1 - 0.047 13.8 0.5 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 Heavy-metal-associated domain Fibrinogen_C PF00147.13 KFP00289.1 - 2.1e-82 276.2 9.1 2.8e-82 275.8 6.3 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain FlaC_arch PF05377.6 KFP00289.1 - 0.00049 19.9 2.5 0.0056 16.5 0.4 2.6 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 KFP00289.1 - 0.3 10.8 6.8 0.15 11.8 2.4 1.9 2 0 0 2 2 2 0 Laminin Domain II Uds1 PF15456.1 KFP00289.1 - 0.57 10.1 5.1 1.2 9.1 3.5 1.5 1 0 0 1 1 1 0 Up-regulated During Septation Prefoldin PF02996.12 KFP00289.1 - 0.78 9.3 6.5 8 6.1 0.7 2.5 2 0 0 2 2 2 0 Prefoldin subunit IncA PF04156.9 KFP00289.1 - 1.3 8.5 7.6 0.86 9.1 0.6 2.2 1 1 1 2 2 2 0 IncA protein DUF16 PF01519.11 KFP00289.1 - 7.3 6.8 8.9 17 5.7 6.1 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 GSAP-16 PF14959.1 KFP00290.1 - 7e-42 141.7 0.0 2.8e-41 139.8 0.0 2.1 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term Y_phosphatase PF00102.22 KFP00291.1 - 1.5e-82 276.5 0.2 2e-82 276.0 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFP00291.1 - 0.0034 17.6 0.0 0.0088 16.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 KFP00291.1 - 0.0036 16.9 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFP00291.1 - 0.015 15.3 0.9 0.072 13.1 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate JmjC PF02373.17 KFP00292.1 - 0.46 10.7 0.0 0.46 10.7 0.0 2.3 2 1 0 2 2 2 0 JmjC domain, hydroxylase Tmemb_185A PF10269.4 KFP00293.1 - 3.5e-09 36.6 19.9 5.8e-06 26.0 7.3 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein DUF3522 PF12036.3 KFP00293.1 - 0.11 12.2 5.7 0.21 11.3 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) CoA_binding_3 PF13727.1 KFP00293.1 - 0.89 9.3 14.4 0.039 13.7 3.2 2.0 1 1 1 2 2 2 0 CoA-binding domain DUF1275 PF06912.6 KFP00293.1 - 1.3 8.2 7.4 0.43 9.7 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) DUF1430 PF07242.6 KFP00293.1 - 3.3 7.8 8.4 8.4 6.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Phtf-FEM1B_bdg PF12129.3 KFP00294.1 - 3e-79 263.9 0.3 3e-79 263.9 0.2 2.1 2 0 0 2 2 2 1 Male germ-cell putative homeodomain transcription factor PDZ PF00595.19 KFP00295.1 - 7.6e-61 202.2 10.3 3.1e-15 56.0 0.0 5.5 5 0 0 5 5 5 5 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP00295.1 - 4.5e-30 103.3 0.2 2.9e-05 23.8 0.0 5.3 5 0 0 5 5 5 5 PDZ domain WW PF00397.21 KFP00295.1 - 7.6e-16 57.6 6.7 4.7e-09 35.9 0.2 3.0 3 0 0 3 3 3 2 WW domain Guanylate_kin PF00625.16 KFP00295.1 - 6.8e-09 35.4 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase Tricorn_PDZ PF14685.1 KFP00295.1 - 7.7e-07 28.8 2.4 1.4 8.7 0.0 5.1 5 0 0 5 5 5 3 Tricorn protease PDZ domain YodL PF14191.1 KFP00295.1 - 0.083 13.3 0.0 0.3 11.5 0.0 2.0 1 0 0 1 1 1 0 YodL-like G-alpha PF00503.15 KFP00297.1 - 3.5e-132 440.7 3.7 4.1e-132 440.5 2.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP00297.1 - 7.6e-16 57.8 0.8 1.2e-11 44.1 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP00297.1 - 0.011 14.8 3.2 1.2 8.2 0.4 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 KFP00297.1 - 0.042 14.3 0.1 1 9.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KFP00297.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2951 PF11166.3 KFP00297.1 - 0.083 12.7 0.2 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) CD36 PF01130.16 KFP00298.1 - 2.2e-139 464.8 0.0 2.5e-139 464.6 0.0 1.0 1 0 0 1 1 1 1 CD36 family Sema PF01403.14 KFP00299.1 - 1.2e-166 554.5 0.0 1.6e-166 554.1 0.0 1.2 1 0 0 1 1 1 1 Sema domain I-set PF07679.11 KFP00299.1 - 9.2e-06 25.4 0.3 2.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain V-set PF07686.12 KFP00299.1 - 0.00016 21.5 0.3 0.00074 19.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin V-set domain PSI PF01437.20 KFP00299.1 - 0.0003 20.8 8.2 0.0003 20.8 5.7 2.4 2 0 0 2 2 2 1 Plexin repeat Ig_2 PF13895.1 KFP00299.1 - 0.0018 18.3 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP00299.1 - 0.0094 16.4 0.0 0.039 14.4 0.0 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Kringle PF00051.13 KFP00300.1 - 2.2e-109 357.7 41.5 4.2e-29 100.4 4.3 4.5 4 0 0 4 4 4 4 Kringle domain Trypsin PF00089.21 KFP00300.1 - 1.5e-47 162.0 0.1 2.8e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin PAN_1 PF00024.21 KFP00300.1 - 1.8e-10 40.3 1.0 6.1e-10 38.7 0.7 1.9 1 0 0 1 1 1 1 PAN domain DUF1986 PF09342.6 KFP00300.1 - 0.00053 19.3 0.0 0.00094 18.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) VGCC_alpha2 PF08473.6 KFP00301.1 - 2.8e-47 158.3 0.4 5.7e-47 157.4 0.3 1.5 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd VWA_N PF08399.6 KFP00301.1 - 1.1e-41 142.2 0.4 3.9e-41 140.5 0.2 2.0 1 0 0 1 1 1 1 VWA N-terminal Cache_1 PF02743.13 KFP00301.1 - 4.8e-28 96.5 0.2 2.5e-27 94.2 0.0 2.2 2 0 0 2 2 2 1 Cache domain VWA PF00092.23 KFP00301.1 - 2.4e-20 73.0 0.3 4.5e-20 72.1 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFP00301.1 - 6.8e-13 49.0 0.0 1.4e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFP00301.1 - 7.8e-13 48.3 0.0 1.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFP00301.1 - 0.0016 18.3 0.3 0.0038 17.0 0.2 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus Cache_2 PF08269.6 KFP00301.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Cache domain Sema PF01403.14 KFP00304.1 - 5.5e-169 562.2 0.0 7.8e-169 561.7 0.0 1.2 1 0 0 1 1 1 1 Sema domain V-set PF07686.12 KFP00304.1 - 5.4e-05 23.0 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain PSI PF01437.20 KFP00304.1 - 0.00051 20.1 6.9 0.00051 20.1 4.8 1.9 2 0 0 2 2 2 1 Plexin repeat ig PF00047.20 KFP00304.1 - 0.0069 16.4 0.1 0.053 13.6 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin domain Sema PF01403.14 KFP00305.1 - 1.2e-176 587.5 0.0 4.6e-176 585.5 0.0 1.8 2 0 0 2 2 2 1 Sema domain V-set PF07686.12 KFP00305.1 - 3.4e-06 26.9 0.0 9.4e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain PSI PF01437.20 KFP00305.1 - 0.00018 21.6 7.2 0.00018 21.6 5.0 2.1 2 0 0 2 2 2 1 Plexin repeat ig PF00047.20 KFP00305.1 - 0.00053 20.0 0.0 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFP00305.1 - 0.0012 18.8 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP00305.1 - 0.021 15.3 0.0 1.3 9.5 0.0 3.2 3 0 0 3 3 3 0 Immunoglobulin domain I-set PF07679.11 KFP00305.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Sema PF01403.14 KFP00306.1 - 1.1e-171 571.1 0.0 4.9e-171 569.0 0.0 1.8 1 1 1 2 2 2 2 Sema domain V-set PF07686.12 KFP00306.1 - 3.8e-05 23.5 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin V-set domain PSI PF01437.20 KFP00306.1 - 0.00014 21.9 9.4 0.00033 20.7 6.5 1.6 1 0 0 1 1 1 1 Plexin repeat I-set PF07679.11 KFP00306.1 - 0.00069 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP00306.1 - 0.0031 17.5 0.1 0.017 15.2 0.0 2.3 3 0 0 3 3 3 1 Immunoglobulin domain WD40 PF00400.27 KFP00306.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat ANF_receptor PF01094.23 KFP00307.1 - 1.6e-93 313.2 0.2 2e-93 312.9 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFP00307.1 - 1.3e-79 266.9 22.2 2.2e-79 266.1 15.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFP00307.1 - 2.9e-15 55.7 9.9 7.3e-15 54.4 6.9 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFP00307.1 - 2.4e-09 37.0 0.1 4.9e-09 35.9 0.1 1.6 2 1 0 2 2 2 1 Periplasmic binding protein GCC2_GCC3 PF07699.8 KFP00308.1 - 2.2e-10 39.9 71.3 1.1e-05 24.8 4.5 8.6 5 3 3 8 8 8 7 GCC2 and GCC3 Myb_DNA-binding PF00249.26 KFP00310.1 - 1.8e-22 79.1 9.6 6.2e-14 51.7 0.3 4.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFP00310.1 - 7.9e-22 77.1 8.3 2e-14 53.4 0.1 4.6 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFP00310.1 - 0.031 14.3 0.5 0.031 14.3 0.3 3.7 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF2678 PF10856.3 KFP00311.1 - 1.8e-47 159.8 6.3 2e-47 159.7 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) Polysacc_synt_C PF14667.1 KFP00311.1 - 5.9e-05 22.9 1.8 7.5e-05 22.5 1.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain ABC2_membrane_3 PF12698.2 KFP00311.1 - 0.09 11.7 4.8 0.11 11.5 3.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF95 PF01944.12 KFP00311.1 - 0.11 12.0 1.7 0.14 11.7 1.2 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF95 Peptidase_M50 PF02163.17 KFP00311.1 - 0.31 9.9 3.5 5.2 5.9 0.0 2.0 1 1 1 2 2 2 0 Peptidase family M50 7TMR-DISM_7TM PF07695.6 KFP00311.1 - 1.2 8.8 12.5 4.5 6.8 8.6 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling YesK PF14150.1 KFP00311.1 - 4.8 7.3 10.0 0.32 11.1 1.8 2.1 1 1 1 2 2 2 0 YesK-like protein DUF2417 PF10329.4 KFP00311.1 - 4.9 6.4 6.7 6.9 5.9 4.7 1.3 1 1 0 1 1 1 0 Region of unknown function (DUF2417) DUF4131 PF13567.1 KFP00311.1 - 6 6.2 8.6 0.51 9.7 1.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Meiosis_expr PF15163.1 KFP00312.1 - 3.5e-37 126.6 10.9 4.1e-37 126.3 7.6 1.1 1 0 0 1 1 1 1 Meiosis-expressed DRMBL PF07522.9 KFP00313.1 - 2.5e-17 62.8 0.0 5.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFP00313.1 - 1.9e-05 24.3 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFP00313.1 - 0.0095 15.6 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SET PF00856.23 KFP00314.1 - 2.6e-27 96.0 0.1 9.9e-27 94.2 0.1 1.9 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 KFP00314.1 - 8.3e-22 77.4 2.7 8.3e-22 77.4 1.9 2.4 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 KFP00314.1 - 7.5e-14 51.1 2.0 1.7e-13 50.0 1.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HSP70 PF00012.15 KFP00315.1 - 6.5e-107 357.9 0.1 7.3e-107 357.7 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFP00315.1 - 1.9e-11 43.1 0.0 3.2e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein B5 PF03484.10 KFP00315.1 - 0.011 15.5 0.1 0.45 10.3 0.0 2.7 2 1 0 2 2 2 0 tRNA synthetase B5 domain DUF1151 PF06625.6 KFP00316.1 - 1.2e-51 173.6 22.0 1.3e-51 173.3 15.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) DUF4045 PF13254.1 KFP00316.1 - 0.37 10.0 12.3 0.17 11.1 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4045) AICARFT_IMPCHas PF01808.13 KFP00316.1 - 1.5 7.7 4.8 1.9 7.5 3.4 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme DUF3338 PF11819.3 KFP00317.1 - 1.4e-60 202.6 5.0 1.4e-60 202.6 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_M PF00373.13 KFP00317.1 - 5.6e-20 71.7 0.0 5.6e-20 71.7 0.0 3.1 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFP00317.1 - 1e-12 47.8 0.2 4.3e-12 45.9 0.1 2.2 2 0 0 2 2 2 1 FERM N-terminal domain FERM_C PF09380.5 KFP00317.1 - 5.8e-06 26.4 0.0 2.9e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 FERM C-terminal PH-like domain Prp18 PF02840.10 KFP00318.1 - 1e-58 197.2 0.1 1.9e-58 196.3 0.1 1.4 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 KFP00318.1 - 2.4e-13 49.0 3.6 2.4e-13 49.0 2.5 2.2 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Phage_int_SAM_4 PF13495.1 KFP00318.1 - 0.072 13.4 0.1 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain BEN PF10523.4 KFP00319.1 - 1.8e-12 47.1 0.1 5.7e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 BEN domain AIRS_C PF02769.17 KFP00321.1 - 1e-26 93.7 0.0 1.6e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KFP00321.1 - 2.7e-11 43.5 0.1 6.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PhyH PF05721.8 KFP00322.1 - 2.7e-44 151.7 0.0 3.4e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mcm10 PF09332.6 KFP00323.1 - 5.1e-135 450.2 9.4 5.1e-135 450.2 6.5 2.6 2 0 0 2 2 2 1 Mcm10 replication factor zf-primase PF09329.6 KFP00323.1 - 1e-17 63.4 2.2 2.7e-17 62.0 1.5 1.8 1 0 0 1 1 1 1 Primase zinc finger DUF3138 PF11336.3 KFP00323.1 - 0.16 10.1 1.3 0.31 9.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NEMO PF11577.3 KFP00324.1 - 2.2e-29 100.9 13.2 2.2e-29 100.9 9.1 5.5 5 1 1 6 6 6 2 NF-kappa-B essential modulator NEMO HALZ PF02183.13 KFP00324.1 - 0.022 14.4 0.8 0.022 14.4 0.5 7.2 8 1 1 9 9 9 0 Homeobox associated leucine zipper IL17 PF06083.6 KFP00324.1 - 0.06 13.4 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Interleukin-17 PMT_C PF11647.3 KFP00324.1 - 0.14 11.8 0.1 0.14 11.8 0.1 3.4 2 1 2 4 4 4 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Reo_sigmaC PF04582.7 KFP00324.1 - 1.4 8.0 10.2 0.71 8.9 2.5 2.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein YscO PF07321.7 KFP00325.1 - 7.2e-07 29.1 10.9 9.7e-07 28.7 7.6 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO Myosin_tail_1 PF01576.14 KFP00325.1 - 0.00013 19.8 5.7 0.00015 19.6 3.9 1.0 1 0 0 1 1 1 1 Myosin tail bZIP_1 PF00170.16 KFP00325.1 - 0.00086 19.2 3.7 0.00086 19.2 2.5 1.8 1 1 1 2 2 1 1 bZIP transcription factor Fib_alpha PF08702.5 KFP00325.1 - 0.0017 18.4 2.2 0.0029 17.7 1.5 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 KFP00325.1 - 0.0021 17.8 8.7 0.0029 17.4 6.0 1.1 1 0 0 1 1 1 1 Tropomyosin like AAA_13 PF13166.1 KFP00325.1 - 0.003 16.1 2.0 0.0038 15.7 1.4 1.1 1 0 0 1 1 1 1 AAA domain KLRAQ PF10205.4 KFP00325.1 - 0.003 17.5 8.8 0.0047 16.9 6.1 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein DUF489 PF04356.7 KFP00325.1 - 0.0031 17.1 1.7 0.0039 16.7 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) Herpes_UL6 PF01763.11 KFP00325.1 - 0.0044 15.2 3.2 0.0047 15.1 2.2 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF1664 PF07889.7 KFP00325.1 - 0.0045 16.7 2.7 0.0059 16.3 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) FH2 PF02181.18 KFP00325.1 - 0.0051 15.7 2.3 0.0056 15.6 1.6 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Cluap1 PF10234.4 KFP00325.1 - 0.0062 15.7 5.9 0.0069 15.6 4.1 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Atg14 PF10186.4 KFP00325.1 - 0.0062 15.5 7.0 0.0069 15.3 4.8 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 PspA_IM30 PF04012.7 KFP00325.1 - 0.0062 15.9 5.4 0.0073 15.6 3.8 1.2 1 0 0 1 1 1 1 PspA/IM30 family Laminin_I PF06008.9 KFP00325.1 - 0.0076 15.6 7.0 0.0091 15.3 4.9 1.1 1 0 0 1 1 1 1 Laminin Domain I Mnd1 PF03962.10 KFP00325.1 - 0.0079 15.8 3.4 0.0081 15.8 2.4 1.2 1 0 0 1 1 1 1 Mnd1 family IncA PF04156.9 KFP00325.1 - 0.0079 15.8 6.7 0.0098 15.5 4.6 1.1 1 0 0 1 1 1 1 IncA protein TMF_DNA_bd PF12329.3 KFP00325.1 - 0.0098 15.6 9.9 0.014 15.2 6.8 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding RRF_GI PF12614.3 KFP00325.1 - 0.01 15.6 2.8 0.018 14.8 1.8 1.5 1 1 0 1 1 1 0 Ribosome recycling factor Snapin_Pallidin PF14712.1 KFP00325.1 - 0.013 15.8 4.2 0.021 15.1 2.9 1.4 1 0 0 1 1 1 0 Snapin/Pallidin EzrA PF06160.7 KFP00325.1 - 0.013 13.6 2.8 0.014 13.5 1.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FlaC_arch PF05377.6 KFP00325.1 - 0.014 15.3 0.7 0.028 14.2 0.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Rabaptin PF03528.10 KFP00325.1 - 0.015 15.1 4.0 0.018 14.9 2.8 1.3 1 0 0 1 1 1 0 Rabaptin P4Ha_N PF08336.6 KFP00325.1 - 0.016 15.0 3.4 0.025 14.4 2.3 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spc7 PF08317.6 KFP00325.1 - 0.017 13.7 5.2 0.019 13.6 3.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein EMP24_GP25L PF01105.19 KFP00325.1 - 0.02 14.6 3.6 0.026 14.2 2.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Rootletin PF15035.1 KFP00325.1 - 0.021 14.8 8.1 0.025 14.5 5.6 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Laminin_II PF06009.7 KFP00325.1 - 0.021 14.5 3.7 0.029 14.1 2.6 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF3450 PF11932.3 KFP00325.1 - 0.022 14.0 3.4 0.022 14.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pox_I3 PF04661.7 KFP00325.1 - 0.028 13.2 0.2 0.035 12.9 0.2 1.2 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein DUF972 PF06156.8 KFP00325.1 - 0.028 14.7 4.7 0.042 14.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 KFP00325.1 - 0.03 14.4 4.0 0.056 13.5 2.7 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 KFP00325.1 - 0.031 13.3 4.2 0.035 13.1 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Striatin PF08232.7 KFP00325.1 - 0.042 14.1 5.3 0.055 13.7 3.6 1.3 1 0 0 1 1 1 0 Striatin family HemX PF04375.9 KFP00325.1 - 0.043 12.4 4.8 0.05 12.1 3.3 1.2 1 0 0 1 1 1 0 HemX DUF4570 PF15134.1 KFP00325.1 - 0.043 13.6 4.4 0.06 13.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) SpoVIF PF14069.1 KFP00325.1 - 0.044 13.5 3.1 0.091 12.5 2.2 1.6 1 1 0 1 1 1 0 Stage VI sporulation protein F NPV_P10 PF05531.7 KFP00325.1 - 0.044 14.0 2.2 0.72 10.1 1.4 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.3 KFP00325.1 - 0.048 13.5 10.7 0.066 13.1 7.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cauli_AT PF03233.8 KFP00325.1 - 0.052 13.2 1.9 0.067 12.8 1.3 1.3 1 0 0 1 1 1 0 Aphid transmission protein DUF724 PF05266.9 KFP00325.1 - 0.064 12.8 5.9 0.086 12.4 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 KFP00325.1 - 0.069 11.0 5.3 0.08 10.7 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KFP00325.1 - 0.071 12.6 8.4 0.12 11.8 5.7 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 KFP00325.1 - 0.079 13.2 9.0 0.12 12.6 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Ax_dynein_light PF10211.4 KFP00325.1 - 0.093 12.5 9.2 0.13 12.1 6.4 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain PRKCSH-like PF12999.2 KFP00325.1 - 0.099 12.2 2.0 0.13 11.8 1.4 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like GrpE PF01025.14 KFP00325.1 - 0.11 12.0 5.9 0.15 11.6 4.1 1.2 1 0 0 1 1 1 0 GrpE Prominin PF05478.6 KFP00325.1 - 0.12 9.8 3.3 0.15 9.5 2.3 1.1 1 0 0 1 1 1 0 Prominin DegS PF05384.6 KFP00325.1 - 0.12 11.5 7.1 0.12 11.5 3.9 1.4 1 1 0 1 1 1 0 Sensor protein DegS TMPIT PF07851.8 KFP00325.1 - 0.13 11.2 4.0 0.18 10.8 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Med4 PF10018.4 KFP00325.1 - 0.17 11.2 4.2 0.24 10.7 2.9 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Fzo_mitofusin PF04799.8 KFP00325.1 - 0.18 11.2 3.3 0.22 10.8 2.3 1.4 1 0 0 1 1 1 0 fzo-like conserved region SlyX PF04102.7 KFP00325.1 - 0.18 12.1 6.1 0.67 10.3 4.2 1.9 1 1 0 1 1 1 0 SlyX DUF3552 PF12072.3 KFP00325.1 - 0.19 10.9 8.7 0.24 10.5 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) AIG1 PF04548.11 KFP00325.1 - 0.2 10.7 3.1 0.26 10.3 2.2 1.2 1 0 0 1 1 1 0 AIG1 family DUF2951 PF11166.3 KFP00325.1 - 0.24 11.2 7.3 0.5 10.2 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) UPF0242 PF06785.6 KFP00325.1 - 0.29 9.7 4.9 0.35 9.4 3.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF342 PF03961.8 KFP00325.1 - 0.31 9.3 3.6 0.34 9.2 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) COG2 PF06148.6 KFP00325.1 - 0.39 10.5 5.7 0.61 9.9 3.9 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF334 PF03904.8 KFP00325.1 - 0.42 9.8 4.4 0.48 9.6 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Adeno_PIX PF03955.9 KFP00325.1 - 0.47 10.9 2.0 0.67 10.5 0.6 1.7 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Cep57_CLD_2 PF14197.1 KFP00325.1 - 0.49 10.3 10.2 0.85 9.6 7.1 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.17 KFP00325.1 - 0.53 10.3 8.3 0.76 9.8 5.8 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.4 KFP00325.1 - 0.58 10.1 5.0 0.59 10.0 2.8 1.5 1 1 1 2 2 2 0 Haemolysin XhlA DUF3373 PF11853.3 KFP00325.1 - 0.79 8.1 3.2 0.97 7.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Synaptobrevin PF00957.16 KFP00325.1 - 1.5 8.5 5.1 2.6 7.7 3.5 1.5 1 1 0 1 1 1 0 Synaptobrevin FUSC-like PF12805.2 KFP00325.1 - 1.6 7.6 5.3 2.3 7.0 3.7 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF4446 PF14584.1 KFP00325.1 - 1.9 8.3 6.1 4.1 7.2 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2681 PF10883.3 KFP00325.1 - 3.4 7.9 9.4 5.5 7.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) NYD-SP28_assoc PF14775.1 KFP00325.1 - 3.6 7.3 6.5 1.8 8.3 0.6 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain Pkinase PF00069.20 KFP00327.1 - 3.7e-76 255.7 0.0 4.4e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00327.1 - 2.8e-35 121.6 0.0 3.5e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP00327.1 - 5.4e-08 32.1 0.0 6.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP00327.1 - 0.00035 19.6 0.0 0.0006 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP00327.1 - 0.00036 19.9 0.1 0.00036 19.9 0.1 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KFP00327.1 - 0.002 17.9 0.0 0.19 11.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP00327.1 - 0.0079 15.5 0.1 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 KFP00327.1 - 0.056 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase D123 PF07065.9 KFP00328.1 - 6.9e-102 340.5 0.2 7.8e-102 340.3 0.1 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 KFP00328.1 - 3e-05 23.8 0.0 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) DUF466 PF04328.8 KFP00328.1 - 0.067 13.0 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF466) ATPgrasp_YheCD PF14398.1 KFP00328.1 - 0.083 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp NUDIX PF00293.23 KFP00329.1 - 3.2e-18 65.6 0.1 6.3e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain SecY PF00344.15 KFP00330.1 - 3e-93 312.4 16.0 4.1e-93 312.0 11.1 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KFP00330.1 - 1.5e-19 69.2 0.3 4.4e-19 67.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p YlaH PF14036.1 KFP00330.1 - 0.16 12.0 5.5 1.3 9.1 0.1 3.3 3 0 0 3 3 3 0 YlaH-like protein Transket_pyr PF02779.19 KFP00331.1 - 4.4e-63 211.9 0.0 7.2e-63 211.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFP00331.1 - 3.6e-43 147.3 0.0 7.6e-43 146.3 0.0 1.4 1 1 0 1 1 1 1 Dehydrogenase E1 component Fmp27 PF10344.4 KFP00332.1 - 7.7 4.0 15.9 7.8 4.0 11.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 MIF4G PF02854.14 KFP00333.1 - 1.1e-39 136.0 0.0 1.7e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain Upf2 PF04050.9 KFP00333.1 - 2.4e-29 102.2 12.3 2.4e-29 102.2 8.5 2.1 1 1 1 2 2 1 1 Up-frameshift suppressor 2 DUF1981 PF09324.5 KFP00333.1 - 0.067 12.7 0.1 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) PqqA PF08042.6 KFP00333.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 PqqA family Nop14 PF04147.7 KFP00333.1 - 0.34 8.7 24.8 0.45 8.3 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family DARPP-32 PF05395.7 KFP00333.1 - 1.1 9.3 12.4 1.9 8.6 8.6 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF1510 PF07423.6 KFP00333.1 - 2.3 7.5 19.2 3.3 7.0 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 KFP00333.1 - 3.5 5.9 23.2 4.5 5.6 16.1 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 KFP00333.1 - 6.9 4.2 7.0 8.7 3.8 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-T PF15511.1 KFP00333.1 - 8.8 5.4 14.3 12 5.0 9.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SDA1 PF05285.7 KFP00333.1 - 9.3 5.4 22.8 12 5.0 15.8 1.1 1 0 0 1 1 1 0 SDA1 SARG PF15385.1 KFP00334.1 - 1.5e-85 288.4 39.5 3.3e-84 284.0 27.4 2.4 1 1 0 1 1 1 1 Specifically androgen-regulated gene protein ECH PF00378.15 KFP00335.1 - 2.9e-51 173.9 0.2 3.2e-51 173.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFP00335.1 - 0.1 12.3 0.9 1 9.1 0.0 2.5 2 1 1 3 3 3 0 Peptidase family S49 RRM_1 PF00076.17 KFP00337.1 - 1.3e-51 172.0 0.0 1.2e-17 63.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00337.1 - 2.9e-38 129.6 0.0 2.7e-12 46.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00337.1 - 2.1e-29 101.0 1.8 1.3e-09 37.7 0.1 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFP00337.1 - 4.4e-07 29.7 0.0 0.31 11.0 0.0 3.6 3 0 0 3 3 3 3 RNA binding domain RRM_3 PF08777.6 KFP00337.1 - 0.022 14.5 0.0 3.7 7.4 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif Limkain-b1 PF11608.3 KFP00337.1 - 0.054 13.2 0.1 2.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 GATA PF00320.22 KFP00339.1 - 4.4e-31 105.9 19.7 1.2e-15 56.4 3.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFP00339.1 - 2e-05 23.7 7.1 0.029 13.6 0.8 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF2387 PF09526.5 KFP00339.1 - 0.043 13.7 6.3 3.7 7.5 0.7 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Prim_Zn_Ribbon PF08273.7 KFP00339.1 - 0.18 11.9 11.0 0.1 12.7 1.5 2.8 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase eIF-5_eIF-2B PF01873.12 KFP00339.1 - 0.18 11.4 5.2 4.2 7.0 0.6 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.2 KFP00339.1 - 0.88 9.4 12.4 12 5.8 6.4 2.9 1 1 2 3 3 3 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KFP00339.1 - 1.8 8.4 13.5 0.74 9.6 2.6 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KFP00339.1 - 3.4 7.3 11.7 2 8.1 0.8 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Cytochrom_c3_2 PF14537.1 KFP00339.1 - 7.5 6.9 12.2 16 5.9 0.3 3.0 2 1 0 3 3 2 0 Cytochrome c3 Elf1 PF05129.8 KFP00339.1 - 7.5 6.3 8.2 9.1 6.0 0.2 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 KFP00339.1 - 9.9 6.2 8.9 2.1 8.3 0.1 3.3 3 1 0 4 4 3 0 Zinc ribbon domain Bromo_TP PF07524.8 KFP00340.1 - 5.3e-17 61.3 0.0 8e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.24 KFP00340.1 - 1e-11 44.3 7.4 2.8e-11 42.9 5.1 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFP00340.1 - 0.0055 15.9 1.7 0.0055 15.9 1.2 2.0 2 0 0 2 2 2 1 PHD-finger ATP-synt PF00231.14 KFP00341.1 - 1.8e-76 257.2 2.3 2.1e-76 257.0 1.6 1.0 1 0 0 1 1 1 1 ATP synthase ACT_4 PF13291.1 KFP00341.1 - 0.09 13.1 1.5 0.24 11.7 0.2 2.1 2 0 0 2 2 2 0 ACT domain Viral_P18 PF04521.8 KFP00341.1 - 0.23 10.8 1.6 6.3 6.2 0.4 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Gp-FAR-1 PF05823.7 KFP00341.1 - 0.48 10.3 3.2 1.9 8.4 0.2 2.5 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Kin17_mid PF10357.4 KFP00342.1 - 6.1e-51 171.3 2.5 6.1e-51 171.3 1.7 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KOW PF00467.24 KFP00342.1 - 0.0005 19.6 0.1 0.0005 19.6 0.0 3.3 2 2 1 3 3 3 1 KOW motif zf-met PF12874.2 KFP00342.1 - 0.025 14.7 8.8 0.055 13.6 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SecM PF06558.7 KFP00342.1 - 0.029 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) zf-C2H2_jaz PF12171.3 KFP00342.1 - 0.19 11.9 8.7 0.41 10.8 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DDHD PF02862.12 KFP00342.1 - 0.55 9.9 5.0 0.9 9.2 3.5 1.4 1 0 0 1 1 1 0 DDHD domain RyR PF02026.11 KFP00342.1 - 0.8 9.7 5.3 4.3 7.4 0.0 3.1 2 1 1 3 3 3 0 RyR domain zf-C2H2_2 PF12756.2 KFP00342.1 - 3.5 7.8 9.9 0.1 12.7 1.6 2.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) RNA_binding PF01877.12 KFP00342.1 - 5.7 6.9 10.1 4.7 7.2 0.7 3.2 2 1 0 3 3 3 0 RNA binding ITI_HC_C PF06668.7 KFP00343.1 - 1e-71 240.2 0.6 2.1e-71 239.2 0.4 1.6 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VWA PF00092.23 KFP00343.1 - 2.1e-21 76.4 0.2 4.2e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFP00343.1 - 1.5e-18 66.9 0.0 2.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KFP00343.1 - 7.4e-17 61.1 0.2 3.2e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KFP00343.1 - 6.5e-16 58.9 0.1 1.2e-15 58.0 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFP00343.1 - 0.00011 21.4 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KFP00343.1 - 0.00018 21.3 0.4 0.00036 20.4 0.3 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2828 PF11443.3 KFP00343.1 - 0.0067 14.6 0.1 0.01 14.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF2201 PF09967.4 KFP00343.1 - 0.012 15.5 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 VWA-like domain (DUF2201) DUF3661 PF12400.3 KFP00344.1 - 1.2e-36 125.6 10.3 1.7e-36 125.1 7.1 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein TB2_DP1_HVA22 PF03134.14 KFP00344.1 - 0.038 13.7 0.5 0.038 13.7 0.4 2.1 1 1 1 2 2 2 0 TB2/DP1, HVA22 family TMEM154 PF15102.1 KFP00344.1 - 0.088 12.5 0.2 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Vpu PF00558.14 KFP00344.1 - 0.17 11.4 3.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 Vpu protein MBT PF02820.13 KFP00345.1 - 4.5e-71 234.7 1.1 1.2e-22 79.5 0.1 4.5 4 0 0 4 4 4 4 mbt repeat DUF3588 PF12140.3 KFP00345.1 - 4.7e-43 146.0 0.2 8.2e-43 145.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_PNT PF02198.11 KFP00345.1 - 0.00022 20.9 0.0 0.00055 19.6 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.25 KFP00345.1 - 0.00045 20.3 0.0 0.00092 19.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP00345.1 - 0.043 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) 6PF2K PF01591.13 KFP00346.1 - 1e-104 348.5 0.0 1.7e-104 347.7 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFP00346.1 - 1.7e-36 125.7 0.1 3.5e-36 124.6 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFP00346.1 - 4.9e-08 32.9 0.0 9.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFP00346.1 - 5.7e-05 23.9 0.1 0.00025 21.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KFP00346.1 - 0.00028 20.2 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KFP00346.1 - 0.00049 19.2 0.0 0.0014 17.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin His_Phos_2 PF00328.17 KFP00346.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) G-patch PF01585.18 KFP00347.1 - 1.5e-12 47.0 1.3 3.8e-12 45.7 0.9 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 KFP00347.1 - 7.3e-08 32.1 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP00347.1 - 0.00015 21.3 0.1 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.6 KFP00347.1 - 5 5.6 5.7 7 5.2 4.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sushi PF00084.15 KFP00348.1 - 3e-10 40.2 1.6 4.1e-10 39.8 1.1 1.2 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Endonuclease_NS PF01223.18 KFP00349.1 - 3.1e-24 85.7 0.5 3.6e-24 85.5 0.3 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 KFP00349.1 - 0.00015 21.8 0.6 0.00039 20.4 0.4 1.8 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Muskelin_N PF06588.6 KFP00351.1 - 3.6e-90 300.9 0.5 5.6e-90 300.3 0.4 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 KFP00351.1 - 6.8e-24 83.4 9.1 2.9e-11 43.1 0.0 5.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP00351.1 - 2.1e-21 75.4 11.8 1.6e-05 24.5 0.2 7.3 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KFP00351.1 - 8.9e-18 63.5 11.8 2.6e-05 23.6 0.2 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFP00351.1 - 6e-15 54.6 4.7 0.0068 16.5 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KFP00351.1 - 5.6e-13 48.5 10.1 0.0045 16.9 0.0 6.1 6 1 0 6 6 6 4 Kelch motif F5_F8_type_C PF00754.20 KFP00351.1 - 1.1e-06 28.5 0.0 3.2e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.10 KFP00351.1 - 1.2e-05 24.8 12.3 0.087 12.6 0.1 6.1 6 1 1 7 7 7 2 Kelch motif Sad1_UNC PF07738.8 KFP00351.1 - 0.037 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal CD34_antigen PF06365.7 KFP00352.1 - 3.6e-53 180.2 1.1 3.9e-53 180.1 0.8 1.0 1 0 0 1 1 1 1 CD34/Podocalyxin family IncA PF04156.9 KFP00352.1 - 0.0034 16.9 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 IncA protein EphA2_TM PF14575.1 KFP00352.1 - 0.026 14.9 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Plexin_cytopl PF08337.7 KFP00353.1 - 2e-253 841.6 0.6 2.5e-253 841.3 0.4 1.1 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.19 KFP00353.1 - 6.2e-43 144.7 4.2 2.4e-13 49.8 0.1 6.4 7 0 0 7 7 7 4 IPT/TIG domain PSI PF01437.20 KFP00353.1 - 4.1e-23 81.2 57.9 1.4e-10 41.1 9.9 3.6 3 0 0 3 3 3 3 Plexin repeat DUF948 PF06103.6 KFP00353.1 - 0.011 15.5 0.3 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MTS PF05175.9 KFP00353.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain IncA PF04156.9 KFP00353.1 - 0.031 13.8 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 IncA protein Sema PF01403.14 KFP00354.1 - 8.3e-52 176.1 0.0 9.8e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Sema domain Imm31 PF15595.1 KFP00354.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 31 DUF737 PF05300.6 KFP00355.1 - 1.9e-38 132.3 24.9 2.6e-38 131.8 17.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) CHCH PF06747.8 KFP00355.1 - 0.00034 20.4 1.1 0.00062 19.6 0.8 1.5 1 0 0 1 1 1 1 CHCH domain DUF3287 PF11690.3 KFP00355.1 - 0.0073 16.3 0.3 0.0073 16.3 0.2 2.1 1 1 2 3 3 3 1 Protein of unknown function (DUF3287) DUF3110 PF11360.3 KFP00355.1 - 0.11 12.2 0.5 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Sec20 PF03908.8 KFP00355.1 - 0.15 11.7 0.9 0.31 10.7 0.6 1.6 1 0 0 1 1 1 0 Sec20 DUF1690 PF07956.6 KFP00355.1 - 0.25 11.3 10.7 0.094 12.6 5.3 1.8 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) C_GCAxxG_C_C PF09719.5 KFP00355.1 - 0.38 10.5 1.9 0.89 9.3 1.3 1.8 1 1 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Peptidase_S46 PF10459.4 KFP00355.1 - 1.7 6.9 9.7 2 6.6 6.7 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF2361 PF10153.4 KFP00355.1 - 4.7 7.4 18.2 1.8 8.7 2.9 2.4 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) SPX PF03105.14 KFP00355.1 - 5.2 6.7 9.9 6.6 6.4 6.9 1.1 1 0 0 1 1 1 0 SPX domain DUF2570 PF10828.3 KFP00355.1 - 6.1 6.4 7.9 1.1 8.9 2.1 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) DUF2451 PF10474.4 KFP00356.1 - 0.0026 17.5 0.7 0.012 15.4 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Guanylate_kin PF00625.16 KFP00358.1 - 5e-28 97.7 0.0 9.3e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase LRR_4 PF12799.2 KFP00358.1 - 1.9e-22 78.3 35.2 5.2e-08 32.3 5.4 5.3 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP00358.1 - 2.1e-14 53.0 34.3 2.3e-06 27.2 2.8 4.7 1 1 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 KFP00358.1 - 2.1e-10 39.1 28.7 0.046 13.7 0.5 8.5 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.1 KFP00358.1 - 1.8e-07 30.5 33.0 0.054 13.5 0.5 7.9 4 3 4 8 8 8 5 Leucine Rich repeat LRR_7 PF13504.1 KFP00358.1 - 5.3e-05 22.7 25.7 0.93 9.9 0.3 7.8 7 1 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 KFP00358.1 - 0.00055 19.5 5.2 0.23 11.0 0.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat UAA PF08449.6 KFP00359.1 - 3.9e-98 328.1 22.2 4.8e-98 327.8 15.4 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KFP00359.1 - 1.6e-07 31.0 11.7 1.6e-07 31.0 8.1 2.7 1 1 2 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KFP00359.1 - 0.0025 16.9 3.9 0.0025 16.9 2.7 1.8 1 1 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 KFP00359.1 - 0.0035 17.3 9.1 0.0035 17.3 6.3 3.1 3 1 0 3 3 3 1 EamA-like transporter family Orbi_NS3 PF01616.11 KFP00359.1 - 0.21 10.5 4.5 0.51 9.2 0.2 2.3 2 1 0 2 2 2 0 Orbivirus NS3 Collagen PF01391.13 KFP00360.1 - 5.7e-88 288.4 397.8 1.1e-08 34.4 20.6 17.1 5 3 9 14 14 14 13 Collagen triple helix repeat (20 copies) VWA PF00092.23 KFP00360.1 - 5e-38 130.5 0.0 3.6e-35 121.2 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain fn3 PF00041.16 KFP00360.1 - 5e-37 125.9 2.0 2.7e-12 46.6 0.0 5.4 5 0 0 5 5 5 5 Fibronectin type III domain VWA_2 PF13519.1 KFP00360.1 - 5.2e-09 36.4 0.0 8.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Big_5 PF13205.1 KFP00360.1 - 0.23 12.0 0.2 8.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain UCN2 PF11613.3 KFP00362.1 - 1.1e-22 79.6 4.8 1.1e-22 79.6 3.3 1.8 2 0 0 2 2 2 1 Agonist of corticotropin releasing factor R2, Urocortin-2 Tad_C PF09977.4 KFP00362.1 - 0.06 14.3 0.0 0.08 13.9 0.0 1.4 1 1 0 1 1 1 0 Putative Tad-like Flp pilus-assembly Nop53 PF07767.6 KFP00362.1 - 0.064 12.2 4.7 0.075 12.0 3.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ExbD PF02472.11 KFP00362.1 - 0.16 11.9 3.4 1.4 8.9 2.4 2.1 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Tubulin PF00091.20 KFP00363.1 - 2.3e-51 174.6 0.0 3.2e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFP00363.1 - 1.9e-43 147.4 0.0 2.8e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain RhoGEF PF00621.15 KFP00364.1 - 5.2e-26 91.6 0.0 4.4e-16 59.2 0.0 2.5 1 1 1 2 2 2 2 RhoGEF domain PH PF00169.24 KFP00364.1 - 7.2e-09 35.8 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_5 PF15405.1 KFP00364.1 - 1.8e-08 34.3 0.3 3.2e-07 30.3 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain EF-hand_1 PF00036.27 KFP00365.1 - 3e-40 132.4 6.1 3.2e-10 38.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFP00365.1 - 2.2e-36 123.7 1.0 2.2e-20 72.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP00365.1 - 3.3e-33 113.0 8.1 1.9e-15 56.2 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFP00365.1 - 3.9e-31 104.0 3.7 1.1e-09 37.3 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFP00365.1 - 8.9e-25 84.8 1.7 6.2e-07 28.4 0.0 4.6 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFP00365.1 - 1.3e-14 53.7 0.0 4.5e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFP00365.1 - 4.1e-08 32.8 0.1 0.0023 17.6 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFP00365.1 - 2.2e-07 30.8 0.0 0.00019 21.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 KFP00365.1 - 8.2e-07 28.9 0.8 1.8e-06 27.7 0.2 1.8 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 KFP00365.1 - 4.8e-06 26.0 1.3 0.044 13.4 0.0 3.5 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 KFP00365.1 - 0.0002 20.9 0.2 0.0048 16.4 0.1 2.8 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 KFP00365.1 - 0.00078 19.4 0.4 0.38 10.7 0.1 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb4 EF-hand_like PF09279.6 KFP00365.1 - 0.0067 16.4 0.7 0.024 14.6 0.2 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 KFP00365.1 - 0.0075 16.0 0.3 2 8.1 0.1 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.3 KFP00365.1 - 0.021 15.2 0.1 5.5 7.4 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Poly_export PF02563.11 KFP00365.1 - 0.06 13.1 0.0 0.56 10.0 0.0 2.4 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein Toprim_2 PF13155.1 KFP00365.1 - 0.11 12.8 0.2 5 7.5 0.1 2.4 1 1 2 3 3 3 0 Toprim-like Fe_hyd_lg_C PF02906.9 KFP00365.1 - 0.11 11.6 0.8 0.37 10.0 0.5 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.1 KFP00365.1 - 0.13 11.8 0.8 1.3 8.6 0.1 2.2 1 1 0 2 2 2 0 RloB-like protein Ank_2 PF12796.2 KFP00366.1 - 8.2e-56 186.3 14.5 1.2e-21 76.8 0.1 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFP00366.1 - 5.3e-55 180.6 12.4 1.1e-09 37.6 0.4 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFP00366.1 - 5.8e-35 119.0 6.0 1.1e-09 38.5 0.6 4.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP00366.1 - 2.3e-33 110.8 5.0 1.9e-05 24.4 0.1 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFP00366.1 - 1.6e-29 101.2 8.4 6.8e-07 29.3 0.1 5.8 3 1 4 7 7 7 5 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFP00366.1 - 2.1e-12 46.6 0.7 3.8e-12 45.8 0.5 1.4 1 0 0 1 1 1 1 SOCS box SeleniumBinding PF11524.3 KFP00367.1 - 0.14 12.2 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Selenium binding protein GDI PF00996.13 KFP00369.1 - 1.5e-214 712.2 0.1 1.8e-214 712.0 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.19 KFP00369.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase EGF PF00008.22 KFP00371.1 - 3.7e-38 129.0 142.1 9.7e-09 35.0 4.0 10.1 10 1 0 10 10 9 6 EGF-like domain DSL PF01414.14 KFP00371.1 - 5.2e-28 96.8 8.4 5.2e-28 96.8 5.9 6.7 4 2 2 6 6 4 1 Delta serrate ligand hEGF PF12661.2 KFP00371.1 - 3.1e-15 55.1 92.0 0.00066 19.5 1.6 10.5 10 0 0 10 10 10 7 Human growth factor-like EGF EGF_CA PF07645.10 KFP00371.1 - 6.9e-06 25.9 27.0 4.2e-05 23.4 6.6 9.6 5 2 3 9 9 7 5 Calcium-binding EGF domain EGF_3 PF12947.2 KFP00371.1 - 6.7e-05 22.7 22.3 0.00063 19.6 7.1 10.0 8 2 1 9 9 8 4 EGF domain EGF_2 PF07974.8 KFP00371.1 - 0.012 15.8 30.7 0.016 15.3 7.8 11.2 11 0 0 11 11 11 0 EGF-like domain DUF899 PF05988.7 KFP00371.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Neur_chan_memb PF02932.11 KFP00371.1 - 0.068 13.0 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.1 KFP00371.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 FAM176 family FXa_inhibition PF14670.1 KFP00371.1 - 0.34 11.0 114.3 0.064 13.3 7.4 10.0 2 1 7 9 9 8 0 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP00371.1 - 0.44 10.2 103.6 0.11 12.1 9.1 9.9 8 3 0 8 8 8 0 Complement Clr-like EGF-like DUF4209 PF13910.1 KFP00372.1 - 3.5e-26 91.0 0.1 1.3e-23 82.8 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) Tctex-1 PF03645.8 KFP00373.1 - 1.6e-21 76.0 1.2 1.9e-21 75.8 0.9 1.1 1 0 0 1 1 1 1 Tctex-1 family PHD PF00628.24 KFP00374.1 - 6.2e-17 61.0 25.5 2.6e-09 36.6 7.5 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.1 KFP00374.1 - 0.00025 20.2 5.1 0.00025 20.2 3.6 2.7 2 1 0 2 2 2 1 PHD-finger Requiem_N PF14051.1 KFP00374.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. zf-PHD-like PF15446.1 KFP00374.1 - 0.056 12.7 17.5 0.026 13.8 1.8 3.0 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain TPR_11 PF13414.1 KFP00376.1 - 1.8e-07 30.6 0.0 3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KFP00376.1 - 3.9e-05 23.2 0.0 0.026 14.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP00376.1 - 0.0012 18.7 0.0 0.0031 17.4 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP00376.1 - 0.0046 16.4 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFP00376.1 - 0.08 13.1 0.0 19 5.7 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP00376.1 - 0.092 12.5 0.0 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat UvrD-helicase PF00580.16 KFP00377.1 - 2.8e-08 33.4 0.3 2.8e-08 33.4 0.2 4.1 4 2 0 4 4 4 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 KFP00377.1 - 1.8e-07 30.9 9.6 8.3e-06 25.4 0.0 5.2 4 1 0 4 4 4 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 KFP00377.1 - 1.2e-06 28.5 0.0 0.044 13.9 0.0 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Clathrin PF00637.15 KFP00377.1 - 2.3e-05 23.9 12.8 0.029 13.9 0.1 4.1 3 1 1 4 4 4 2 Region in Clathrin and VPS Pkinase PF00069.20 KFP00378.1 - 4.5e-79 265.2 0.0 5.1e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00378.1 - 5.8e-37 127.1 0.0 7.1e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP00378.1 - 0.001 18.0 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFP00378.1 - 0.002 17.4 0.3 0.0045 16.3 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 KFP00378.1 - 0.019 14.7 0.0 0.76 9.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KFP00378.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_9 PF14604.1 KFP00379.1 - 2.9e-20 71.5 0.1 1.1e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KFP00379.1 - 2.4e-17 62.1 0.1 2.4e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFP00379.1 - 8e-17 60.3 0.7 5.6e-15 54.4 0.1 2.4 2 0 0 2 2 2 1 SH3 domain C1_1 PF00130.17 KFP00379.1 - 3.1e-09 36.4 11.0 3.1e-09 36.4 7.6 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4206 PF13901.1 KFP00379.1 - 0.0012 18.4 2.3 0.0019 17.7 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) zf-DHHC PF01529.15 KFP00379.1 - 0.0057 16.0 4.4 0.011 15.1 3.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase RNA_POL_M_15KD PF02150.11 KFP00379.1 - 0.11 12.1 1.3 0.24 11.1 0.9 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit C1_3 PF07649.7 KFP00379.1 - 0.46 10.5 4.7 1.9 8.5 3.3 2.2 1 0 0 1 1 1 0 C1-like domain PHD PF00628.24 KFP00379.1 - 0.49 10.1 8.1 1.1 8.9 5.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KFP00379.1 - 8.9 6.4 9.7 23 5.1 6.7 1.7 1 0 0 1 1 1 0 RING-like domain C1_2 PF03107.11 KFP00379.1 - 9.6 6.4 7.6 6.9 6.8 2.7 2.7 3 0 0 3 3 3 0 C1 domain R3H PF01424.17 KFP00380.1 - 2.6e-13 49.4 0.2 8.1e-13 47.8 0.0 1.9 2 0 0 2 2 2 1 R3H domain CLASP_N PF12348.3 KFP00381.1 - 1.5e-54 184.7 8.0 1.4e-38 132.5 0.0 4.2 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.17 KFP00381.1 - 1.7e-15 55.6 12.9 0.0068 16.3 0.0 11.1 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.1 KFP00381.1 - 3.5e-11 43.2 6.0 0.03 14.5 0.2 8.0 5 3 2 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 KFP00381.1 - 4.1e-08 33.4 1.3 0.38 11.3 0.0 6.3 6 0 0 6 6 6 2 HEAT-like repeat Ipi1_N PF12333.3 KFP00381.1 - 4.1e-06 26.6 2.6 0.0083 16.0 0.0 3.8 4 0 0 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation DUF2435 PF10363.4 KFP00381.1 - 4.2e-06 26.5 2.1 0.13 12.2 0.0 3.8 2 1 1 3 3 3 3 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KFP00381.1 - 2e-05 24.5 6.7 0.0013 18.5 0.3 5.3 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.2 KFP00381.1 - 2.4e-05 23.8 2.6 5.4 6.4 0.0 4.9 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.2 KFP00381.1 - 2.6e-05 24.5 4.0 19 5.7 0.0 6.2 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KFP00381.1 - 0.00016 20.1 6.7 0.29 9.4 0.1 5.8 5 1 0 6 6 6 1 Adaptin N terminal region ParcG PF10274.4 KFP00381.1 - 0.00021 21.2 2.2 0.0022 17.9 0.1 3.0 2 1 1 3 3 3 1 Parkin co-regulated protein MMS19_C PF12460.3 KFP00381.1 - 0.0099 14.6 3.1 0.062 12.0 0.2 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal TAN PF11640.3 KFP00381.1 - 0.011 15.5 3.2 0.053 13.2 0.1 3.3 2 1 1 3 3 3 0 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.1 KFP00381.1 - 0.046 12.9 1.8 8.4 5.5 0.0 3.6 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II CP2 PF04516.10 KFP00382.1 - 8e-72 241.1 0.1 1.2e-71 240.5 0.1 1.1 1 0 0 1 1 1 1 CP2 transcription factor SAM_2 PF07647.12 KFP00382.1 - 0.0067 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFP00382.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.25 KFP00382.1 - 0.013 15.7 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LRR_6 PF13516.1 KFP00383.1 - 2.9e-19 66.9 36.5 0.00028 20.6 0.0 10.9 11 0 0 11 11 11 6 Leucine Rich repeat F-box-like PF12937.2 KFP00383.1 - 1.4e-13 50.2 0.6 7.2e-13 48.0 0.4 2.3 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KFP00383.1 - 5.5e-13 48.2 22.9 0.0037 16.8 0.9 6.9 4 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP00383.1 - 3.6e-11 42.6 28.9 0.00032 20.4 1.3 6.2 2 1 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 KFP00383.1 - 1.4e-10 39.6 31.8 0.45 10.7 0.0 11.4 11 1 0 11 11 11 5 Leucine Rich Repeat F-box PF00646.28 KFP00383.1 - 4.6e-08 32.5 2.3 1.1e-07 31.3 0.5 2.6 2 0 0 2 2 2 1 F-box domain LRR_7 PF13504.1 KFP00383.1 - 0.01 15.8 35.4 5.6 7.6 0.1 10.8 9 2 0 9 9 9 0 Leucine rich repeat Mating_N PF12731.2 KFP00383.1 - 0.042 13.7 0.1 1.4 8.8 0.0 2.6 1 1 0 2 2 2 0 Mating-type protein beta 1 Xlink PF00193.12 KFP00384.1 - 5.6e-09 35.9 0.1 1.2e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Extracellular link domain Sushi PF00084.15 KFP00384.1 - 5.5e-07 29.8 0.8 5.5e-07 29.8 0.5 2.2 2 0 0 2 2 2 1 Sushi domain (SCR repeat) SIT PF15330.1 KFP00384.1 - 0.0028 17.7 0.1 0.0097 16.0 0.1 1.9 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.1 KFP00384.1 - 0.013 15.2 1.5 0.068 12.8 1.0 2.3 1 1 0 1 1 1 0 TMEM154 protein family MHC2-interact PF09307.5 KFP00384.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting Ly49 PF08391.5 KFP00384.1 - 0.045 13.8 0.3 0.092 12.8 0.2 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region MLANA PF14991.1 KFP00384.1 - 0.054 13.5 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein melan-A ERGIC_N PF13850.1 KFP00384.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) GAPT PF11770.3 KFP00384.1 - 0.093 12.4 0.2 0.21 11.2 0.2 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) P12 PF12669.2 KFP00384.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Virus attachment protein p12 family TPR_14 PF13428.1 KFP00385.1 - 0.33 11.7 0.1 0.33 11.7 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Whi5 PF08528.6 KFP00385.1 - 0.46 10.1 7.8 2.4 7.8 0.5 2.7 2 0 0 2 2 2 0 Whi5 like TPR_6 PF13174.1 KFP00385.1 - 0.51 10.9 3.2 19 6.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFP00385.1 - 1.4 9.0 6.5 23 5.2 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.23 KFP00386.1 - 2e-13 50.1 0.1 4e-13 49.2 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFP00386.1 - 5.2e-08 32.8 0.0 8.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_35 PF01301.14 KFP00387.1 - 3.9e-106 355.0 0.1 1.5e-105 353.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 KFP00387.1 - 2.6e-13 49.8 0.0 8.8e-09 34.9 0.0 2.2 1 1 1 2 2 2 2 Beta-galactosidase BetaGal_dom4_5 PF13364.1 KFP00387.1 - 6.3e-06 26.4 0.3 8.6e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain 7tm_1 PF00001.16 KFP00388.1 - 2.1e-56 190.9 24.3 2.8e-56 190.5 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00388.1 - 1e-09 37.9 25.9 1.5e-09 37.3 18.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFP00388.1 - 1.1e-05 24.7 21.7 0.0036 16.4 15.0 2.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 60KD_IMP PF02096.15 KFP00388.1 - 0.11 12.0 9.9 0.32 10.6 6.9 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein 7tm_1 PF00001.16 KFP00390.1 - 2.8e-56 190.4 20.6 3.4e-56 190.2 14.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00390.1 - 3.3e-09 36.2 20.6 4.7e-09 35.7 14.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UL2 PF08196.6 KFP00390.1 - 5.3 6.8 9.3 3.1 7.6 0.1 2.9 3 0 0 3 3 3 0 UL2 protein Mito_carr PF00153.22 KFP00391.1 - 1.2e-62 207.6 8.6 2.7e-20 71.8 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Ribosomal_S2 PF00318.15 KFP00392.1 - 3.7e-43 147.1 0.0 1.1e-39 135.8 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 TAT_signal PF10518.4 KFP00392.1 - 1.3 9.2 6.7 0.71 10.0 1.6 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence TMC PF07810.8 KFP00393.1 - 2.3e-38 131.0 1.3 6.9e-38 129.4 0.5 2.2 2 0 0 2 2 2 1 TMC domain SpoIIIAH PF12685.2 KFP00393.1 - 0.052 13.0 0.2 0.052 13.0 0.2 2.5 2 0 0 2 2 2 0 SpoIIIAH-like protein FYVE_2 PF02318.11 KFP00394.1 - 4.1e-24 84.7 22.3 4.4e-24 84.6 15.5 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.7 KFP00394.1 - 0.14 11.6 12.8 0.16 11.5 8.9 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-UDP PF14569.1 KFP00394.1 - 0.76 9.5 13.2 1.1 9.0 9.1 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger Rab_eff_C PF04698.7 KFP00395.1 - 0 1265.8 23.3 0 1265.7 16.1 1.0 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus 53-BP1_Tudor PF09038.5 KFP00395.1 - 0.1 12.4 0.0 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor SUI1 PF01253.17 KFP00396.1 - 2.3e-30 104.2 2.0 2.6e-30 104.0 1.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mitoc_L55 PF09776.4 KFP00396.1 - 0.11 12.0 0.1 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Gastrin PF00918.12 KFP00397.1 - 5.4e-35 120.6 0.0 6.5e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Gastrin/cholecystokinin family HAP1_N PF04849.8 KFP00398.1 - 1.8e-144 480.3 36.5 2.7e-144 479.7 25.3 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Milton PF12448.3 KFP00398.1 - 1.9e-69 233.0 15.7 6.5e-45 153.2 4.5 3.3 4 1 0 4 4 4 2 Kinesin associated protein MCPsignal PF00015.16 KFP00398.1 - 0.22 11.0 9.1 4 6.9 3.8 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mod_r PF07200.8 KFP00398.1 - 1 9.2 32.5 0.13 12.1 6.9 3.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4226 PF10774.4 KFP00398.1 - 2.3 8.2 9.0 0.23 11.4 1.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) IncA PF04156.9 KFP00398.1 - 3 7.4 44.7 47 3.4 11.4 3.4 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 KFP00398.1 - 4.5 6.1 31.2 4.4 6.1 3.1 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 KFP00398.1 - 4.8 7.0 19.1 0.047 13.4 1.1 3.9 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KFP00398.1 - 6.8 7.0 32.8 2 8.7 2.6 4.6 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Arm PF00514.18 KFP00400.1 - 6e-56 184.4 21.1 2.2e-08 33.5 0.1 12.4 13 0 0 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP00400.1 - 2.5e-15 56.5 8.4 7.8e-06 26.0 0.3 5.6 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.17 KFP00400.1 - 5.5e-09 35.3 3.3 3.2 8.0 0.0 6.1 5 0 0 5 5 5 3 HEAT repeat Adaptin_N PF01602.15 KFP00400.1 - 4.1e-07 28.7 2.2 0.00024 19.5 0.6 3.1 3 0 0 3 3 3 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 KFP00400.1 - 6.3e-05 21.4 4.8 0.011 14.0 0.3 3.6 2 1 0 3 3 3 2 Proteasome non-ATPase 26S subunit KAP PF05804.7 KFP00400.1 - 0.00011 20.3 1.4 0.028 12.3 0.0 3.4 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 KFP00400.1 - 0.00079 18.6 3.2 0.19 10.8 0.0 3.9 2 1 1 4 4 4 1 Armadillo-like RIX1 PF08167.7 KFP00400.1 - 0.004 16.8 0.1 0.37 10.4 0.1 2.6 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis RasGEF_N_2 PF14663.1 KFP00400.1 - 0.0067 16.3 6.7 6.1 6.8 0.1 4.6 6 0 0 6 6 6 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd1 PF12717.2 KFP00400.1 - 0.0093 15.8 0.4 0.34 10.7 0.1 3.1 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFP00400.1 - 0.018 15.4 12.5 1.9 9.0 0.1 6.4 7 2 2 9 9 8 0 HEAT-like repeat Yae1_N PF09811.4 KFP00401.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF4604 PF15377.1 KFP00402.1 - 2.2e-24 86.4 18.3 2.4e-24 86.3 12.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Asp-B-Hydro_N PF05279.6 KFP00402.1 - 0.051 13.4 8.4 0.053 13.3 5.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ChlamPMP_M PF07548.6 KFP00402.1 - 0.15 11.8 1.6 0.21 11.3 0.8 1.4 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Transglut_N PF00868.15 KFP00403.1 - 1.5e-32 112.0 0.0 3.6e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.17 KFP00403.1 - 5.9e-15 55.2 0.1 1.7e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 KFP00403.1 - 2.2e-13 50.3 0.0 5.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily zf-DHHC PF01529.15 KFP00404.1 - 7.5e-40 136.1 10.0 7.5e-40 136.1 6.9 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase DC_STAMP PF07782.8 KFP00404.1 - 0.19 11.3 2.7 2.9 7.4 0.0 2.7 3 0 0 3 3 3 0 DC-STAMP-like protein RNase_PH PF01138.16 KFP00405.1 - 1.7e-23 83.3 0.0 2.9e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFP00405.1 - 3.1e-10 39.8 0.1 9.1e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Lectin_C PF00059.16 KFP00406.1 - 9.3e-18 64.8 0.1 1.2e-17 64.4 0.1 1.1 1 0 0 1 1 1 1 Lectin C-type domain DUF333 PF03891.10 KFP00406.1 - 0.0016 18.2 0.8 0.35 10.7 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF333) Chordopox_A33R PF05966.7 KFP00406.1 - 0.0074 15.0 0.1 0.0095 14.7 0.0 1.2 1 0 0 1 1 1 1 Chordopoxvirus A33R protein CUB PF00431.15 KFP00407.1 - 4.7e-05 23.4 0.0 3 7.9 0.0 4.3 4 0 0 4 4 4 2 CUB domain Flavi_propep PF01570.12 KFP00407.1 - 0.053 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide tRNA-synt_1 PF00133.17 KFP00408.1 - 6.6e-51 173.0 2.7 1e-22 79.9 0.3 5.9 2 1 3 5 5 5 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFP00408.1 - 1.1e-31 109.8 0.0 2.7e-21 75.7 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFP00408.1 - 5.9e-13 48.8 0.3 1.3e-12 47.7 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 KFP00408.1 - 2.4e-09 36.7 0.0 3.6e-07 29.6 0.0 2.4 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KFP00408.1 - 0.0013 17.8 0.0 0.89 8.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KFP00408.1 - 0.0014 17.5 0.0 0.0064 15.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 KFP00408.1 - 0.0045 15.7 0.0 0.31 9.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) LIM PF00412.17 KFP00409.1 - 1.2e-32 111.7 34.5 2.5e-12 46.6 4.2 3.2 3 0 0 3 3 3 3 LIM domain Mut7-C PF01927.11 KFP00409.1 - 8.2 6.3 14.1 50 3.8 0.3 3.4 2 1 0 2 2 2 0 Mut7-C RNAse domain Syja_N PF02383.13 KFP00410.1 - 3.6e-93 311.8 0.8 4.6e-93 311.4 0.5 1.1 1 0 0 1 1 1 1 SacI homology domain LSM PF01423.17 KFP00411.1 - 1.1e-18 66.4 0.7 1.8e-18 65.8 0.5 1.3 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 KFP00411.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) LRR_1 PF00560.28 KFP00411.1 - 0.08 13.0 0.1 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 Leucine Rich Repeat SM-ATX PF14438.1 KFP00411.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 KFP00411.1 - 1.1 7.6 10.1 0.18 10.2 4.4 1.5 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) SNF PF00209.13 KFP00412.1 - 6.1e-176 585.9 30.4 7.8e-176 585.5 21.1 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Leu_zip PF15294.1 KFP00413.1 - 6e-118 392.9 34.7 6.7e-118 392.8 24.0 1.0 1 0 0 1 1 1 1 Leucine zipper DNA_photolyase PF00875.13 KFP00413.1 - 0.18 11.5 3.3 3.5 7.3 0.3 2.6 1 1 0 2 2 2 0 DNA photolyase Avidin PF01382.12 KFP00414.1 - 3.6e-11 43.3 0.8 3.7e-11 43.3 0.6 1.0 1 0 0 1 1 1 1 Avidin family ELM2 PF01448.19 KFP00415.1 - 1.9e-15 57.2 0.1 7.1e-15 55.3 0.1 2.0 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.26 KFP00415.1 - 6.8e-05 22.8 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain NEMO PF11577.3 KFP00415.1 - 0.021 14.5 0.5 0.064 13.0 0.2 1.9 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO PKI PF02827.11 KFP00415.1 - 0.026 14.6 1.0 0.19 11.8 0.9 2.3 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor 7tm_4 PF13853.1 KFP00416.1 - 8.7e-62 207.1 11.1 1e-61 206.9 7.7 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFP00416.1 - 3.6e-09 36.1 6.2 4.5e-09 35.8 4.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) dUTPase PF00692.14 KFP00418.1 - 1.3e-17 63.4 0.0 1.8e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP00418.1 - 0.0013 18.6 0.1 0.0026 17.6 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KFP00418.1 - 0.056 13.9 0.4 0.13 12.8 0.1 1.8 2 0 0 2 2 2 0 Aspartyl protease Ribosomal_L22 PF00237.14 KFP00419.1 - 4e-38 129.5 0.1 6.3e-38 128.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4512 PF14975.1 KFP00420.1 - 1.7e-17 63.9 2.7 1.9e-17 63.8 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) EF-hand_1 PF00036.27 KFP00421.1 - 9.2e-07 27.7 4.2 3.1e-06 26.0 0.5 3.0 3 1 1 4 4 4 1 EF hand EF-hand_6 PF13405.1 KFP00421.1 - 3.8e-06 26.3 1.9 1.8e-05 24.2 0.5 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KFP00421.1 - 1.2e-05 24.8 4.7 0.00037 20.0 0.4 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP00421.1 - 3.2e-05 23.0 1.2 3.2e-05 23.0 0.8 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFP00421.1 - 5e-05 23.3 0.6 0.0001 22.3 0.4 1.7 1 1 0 1 1 1 1 EF-hand domain pair AAA PF00004.24 KFP00422.1 - 4.8e-97 321.2 0.0 3.3e-47 160.0 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFP00422.1 - 7.5e-15 55.3 0.4 6.4e-07 29.5 0.1 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KFP00422.1 - 1.5e-13 51.6 0.1 2.2e-05 25.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KFP00422.1 - 2e-13 49.9 0.0 1.5e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFP00422.1 - 1.2e-12 48.0 0.2 0.0002 21.5 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFP00422.1 - 6.6e-12 45.5 0.0 1.6e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 KFP00422.1 - 7.7e-12 44.6 0.0 1.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.9 KFP00422.1 - 6.2e-11 42.1 0.4 3.4e-05 23.5 0.0 3.7 4 2 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFP00422.1 - 1e-10 41.8 0.0 2.9e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KFP00422.1 - 6.7e-09 34.9 0.0 0.00072 18.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 KFP00422.1 - 7e-09 35.6 0.0 0.0032 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFP00422.1 - 1.4e-08 34.4 2.7 0.016 14.6 0.0 4.1 2 2 1 4 4 4 3 AAA domain IstB_IS21 PF01695.12 KFP00422.1 - 1.8e-08 34.0 0.1 0.0076 15.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 KFP00422.1 - 2.8e-08 33.1 0.0 0.0039 16.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Arch_ATPase PF01637.13 KFP00422.1 - 6.9e-08 32.4 0.1 0.23 11.1 0.0 3.9 2 2 1 3 3 3 2 Archaeal ATPase AAA_18 PF13238.1 KFP00422.1 - 7.6e-08 32.7 0.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 KFP00422.1 - 8.9e-08 31.9 0.6 5.4e-05 22.9 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 KFP00422.1 - 1.1e-07 31.9 0.0 0.0047 17.0 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_19 PF13245.1 KFP00422.1 - 2e-07 30.6 1.8 0.0062 16.2 0.3 2.7 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 KFP00422.1 - 2.6e-07 30.0 0.2 0.015 14.4 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KFP00422.1 - 6.9e-07 29.3 0.2 0.061 13.2 0.0 3.1 3 1 1 4 4 2 2 AAA domain Parvo_NS1 PF01057.12 KFP00422.1 - 2.2e-06 26.7 0.1 0.025 13.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NACHT PF05729.7 KFP00422.1 - 2.8e-06 27.1 0.0 0.12 11.9 0.0 4.1 3 1 1 4 4 4 1 NACHT domain KaiC PF06745.8 KFP00422.1 - 3e-06 26.5 0.3 0.34 10.0 0.0 3.4 2 1 1 3 3 3 2 KaiC Sigma54_activ_2 PF14532.1 KFP00422.1 - 5e-06 26.6 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KFP00422.1 - 5.2e-06 26.7 0.1 0.0072 16.6 0.0 3.5 3 1 0 3 3 2 1 ABC transporter DUF815 PF05673.8 KFP00422.1 - 6e-06 25.3 0.0 0.0071 15.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 KFP00422.1 - 6.8e-06 25.8 0.0 0.099 12.2 0.0 3.0 3 1 0 3 3 2 2 Bacterial dnaA protein ResIII PF04851.10 KFP00422.1 - 2.1e-05 24.4 0.0 0.0054 16.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KFP00422.1 - 2.8e-05 23.7 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KFP00422.1 - 5.7e-05 22.1 0.0 0.076 11.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 KFP00422.1 - 6e-05 22.5 0.0 0.31 10.4 0.0 3.0 2 2 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.13 KFP00422.1 - 9.3e-05 22.0 0.0 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 KFP00422.1 - 0.00036 20.1 0.0 0.87 9.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KFP00422.1 - 0.0004 19.6 0.5 0.82 8.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.4 KFP00422.1 - 0.00063 18.8 0.0 0.27 10.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KFP00422.1 - 0.0022 17.5 0.0 0.7 9.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 KFP00422.1 - 0.0044 16.9 1.6 1.1 9.0 0.0 3.0 3 0 0 3 3 2 1 Shikimate kinase NTPase_1 PF03266.10 KFP00422.1 - 0.0049 16.5 0.2 1.2 8.7 0.0 3.3 3 0 0 3 3 3 1 NTPase ATP-synt_ab PF00006.20 KFP00422.1 - 0.007 15.8 0.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 KFP00422.1 - 0.008 16.5 0.0 3.7 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KFP00422.1 - 0.0085 15.0 0.0 2 7.2 0.0 2.8 2 1 0 3 3 3 1 Type II/IV secretion system protein Cytidylate_kin2 PF13189.1 KFP00422.1 - 0.011 15.6 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family UPF0079 PF02367.12 KFP00422.1 - 0.012 15.2 0.1 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KFP00422.1 - 0.015 14.8 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFP00422.1 - 0.019 14.4 0.2 2.1 7.7 0.0 3.6 4 0 0 4 4 4 0 AAA-like domain DNA_ligase_A_C PF04679.10 KFP00422.1 - 0.053 13.9 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region KAP_NTPase PF07693.9 KFP00422.1 - 0.054 12.4 0.0 4.4 6.2 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain Zot PF05707.7 KFP00422.1 - 0.1 12.0 0.3 12 5.2 0.2 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PduV-EutP PF10662.4 KFP00422.1 - 0.16 11.4 0.0 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KFP00422.1 - 0.21 11.5 0.5 21 4.9 0.0 2.9 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.10 KFP00422.1 - 0.21 10.2 0.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Adap_comp_sub PF00928.16 KFP00423.1 - 6.6e-79 264.7 0.0 8e-79 264.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Choline_transpo PF04515.7 KFP00424.1 - 3.1e-125 417.3 47.8 1.2e-124 415.3 20.9 3.0 3 0 0 3 3 3 3 Plasma-membrane choline transporter DZF PF07528.9 KFP00425.1 - 5.2e-103 343.7 0.0 9.5e-103 342.9 0.0 1.4 1 0 0 1 1 1 1 DZF domain dsrm PF00035.20 KFP00425.1 - 3.5e-28 97.9 0.2 7.8e-14 52.0 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFP00425.1 - 1.3e-07 31.7 0.1 0.032 14.5 0.0 2.9 2 0 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 RNA_polI_A14 PF08203.6 KFP00425.1 - 0.024 14.8 0.2 0.067 13.4 0.2 1.8 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 U1snRNP70_N PF12220.3 KFP00425.1 - 1.1 9.6 11.9 3.6 7.9 2.9 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Dynamin_M PF01031.15 KFP00426.1 - 1.3e-100 336.0 3.6 4.6e-100 334.2 1.2 2.4 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.18 KFP00426.1 - 4.2e-42 143.8 0.0 9.9e-42 142.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFP00426.1 - 3.4e-24 84.5 1.5 8.7e-24 83.2 1.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain zf-H2C2_2 PF13465.1 KFP00427.1 - 5.9e-44 146.2 38.1 2e-09 37.2 0.1 6.1 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFP00427.1 - 2.1e-30 103.1 40.9 5.7e-06 26.3 0.2 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFP00427.1 - 8.7e-19 67.1 12.5 0.024 14.7 1.3 6.2 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFP00427.1 - 1.1e-18 66.0 37.5 0.0015 18.7 0.2 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP00427.1 - 2.1e-17 62.3 27.2 0.00055 19.7 0.4 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-RING_3 PF14369.1 KFP00427.1 - 1.7e-10 40.7 21.3 0.055 13.4 0.0 6.1 6 0 0 6 6 6 3 zinc-finger Zn-ribbon_8 PF09723.5 KFP00427.1 - 2.5e-09 36.9 27.0 0.037 13.9 2.6 5.9 4 2 1 5 5 5 4 Zinc ribbon domain XPA_N PF01286.13 KFP00427.1 - 5.5e-09 35.5 15.0 0.13 11.9 0.1 6.1 6 0 0 6 6 6 2 XPA protein N-terminal zf-ribbon_3 PF13248.1 KFP00427.1 - 8.6e-07 27.9 26.4 0.54 9.5 0.4 6.2 6 0 0 6 6 6 3 zinc-ribbon domain zf-Di19 PF05605.7 KFP00427.1 - 4.9e-06 26.5 24.8 0.0015 18.6 1.2 4.7 2 1 3 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding TFIIS_C PF01096.13 KFP00427.1 - 1.2e-05 24.8 20.6 3.3 7.4 0.1 6.3 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KFP00427.1 - 0.00017 21.2 33.6 0.0069 16.1 1.2 4.7 3 2 0 3 3 3 1 Transposase zinc-ribbon domain zf-HIT PF04438.11 KFP00427.1 - 0.0002 20.9 26.7 0.57 9.8 0.2 6.1 6 0 0 6 6 6 2 HIT zinc finger zinc_ribbon_2 PF13240.1 KFP00427.1 - 0.00026 20.3 33.0 0.52 9.8 0.2 6.2 6 0 0 6 6 6 2 zinc-ribbon domain zf-met PF12874.2 KFP00427.1 - 0.00037 20.5 28.0 0.37 11.0 0.0 5.9 6 0 0 6 6 6 1 Zinc-finger of C2H2 type C1_3 PF07649.7 KFP00427.1 - 0.00038 20.4 23.1 3.1 7.8 2.2 6.1 6 0 0 6 6 6 0 C1-like domain zf-LYAR PF08790.6 KFP00427.1 - 0.002 17.7 22.2 0.68 9.6 0.1 6.0 6 0 0 6 6 6 1 LYAR-type C2HC zinc finger DZR PF12773.2 KFP00427.1 - 0.0022 17.7 26.0 16 5.4 5.1 4.2 1 1 1 2 2 2 0 Double zinc ribbon GAGA PF09237.6 KFP00427.1 - 0.0036 16.8 0.0 0.0036 16.8 0.0 3.9 2 2 2 4 4 4 1 GAGA factor zf-trcl PF13451.1 KFP00427.1 - 0.0036 16.8 16.8 4.4 7.0 0.0 5.8 5 1 1 6 6 6 0 Probable zinc-binding domain DNA_RNApol_7kD PF03604.8 KFP00427.1 - 0.0041 16.5 19.1 8.8 5.8 0.1 6.2 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 KFP00427.1 - 0.0088 15.6 20.8 2.9 7.5 1.7 5.8 5 1 0 5 5 5 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFP00427.1 - 0.011 15.4 19.7 2.9 7.6 1.4 5.8 5 1 0 5 5 5 0 zinc-ribbon domain FYDLN_acid PF09538.5 KFP00427.1 - 0.011 16.2 12.8 24 5.5 0.2 5.5 2 1 2 4 4 4 0 Protein of unknown function (FYDLN_acid) DUF1610 PF07754.6 KFP00427.1 - 0.013 15.5 38.4 0.22 11.6 1.1 6.1 6 0 0 6 6 6 0 Domain of unknown function (DUF1610) UPF0547 PF10571.4 KFP00427.1 - 0.02 14.5 29.7 4.5 7.0 0.5 6.2 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 CpXC PF14353.1 KFP00427.1 - 0.035 14.0 20.1 9.3 6.2 0.1 5.9 4 2 2 6 6 6 0 CpXC protein RRN7 PF11781.3 KFP00427.1 - 0.075 12.5 14.6 3.4 7.2 0.0 5.3 6 0 0 6 6 6 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 KFP00427.1 - 0.12 12.1 0.2 0.12 12.1 0.1 5.8 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-CSL PF05207.8 KFP00427.1 - 0.16 11.5 20.0 0.84 9.1 0.8 4.4 2 2 3 5 5 5 0 CSL zinc finger YhfH PF14149.1 KFP00427.1 - 0.17 11.7 30.0 12 5.7 0.1 6.4 6 1 0 6 6 6 0 YhfH-like protein DUF329 PF03884.9 KFP00427.1 - 0.18 11.3 18.9 11 5.7 0.1 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF329) HypA PF01155.14 KFP00427.1 - 0.19 11.4 18.3 1.1 8.9 0.6 3.9 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family LIM PF00412.17 KFP00427.1 - 0.28 11.2 19.6 0.92 9.6 1.2 4.6 1 1 2 4 4 4 0 LIM domain Rubredoxin PF00301.15 KFP00427.1 - 0.3 10.9 15.4 7 6.6 2.0 4.9 5 1 0 5 5 5 0 Rubredoxin C1_4 PF07975.7 KFP00427.1 - 0.32 11.0 22.9 1.2 9.1 1.6 5.1 1 1 3 5 5 5 0 TFIIH C1-like domain DUF164 PF02591.10 KFP00427.1 - 0.33 10.8 19.5 12 5.8 0.1 5.7 6 0 0 6 6 6 0 Putative zinc ribbon domain DUF1272 PF06906.6 KFP00427.1 - 0.4 10.5 0.1 0.4 10.5 0.1 5.1 4 1 0 4 4 3 0 Protein of unknown function (DUF1272) zf-IS66 PF13005.2 KFP00427.1 - 0.69 9.9 22.7 1.9 8.5 0.4 5.8 5 1 1 6 6 6 0 zinc-finger binding domain of transposase IS66 zf-AN1 PF01428.11 KFP00427.1 - 0.71 9.8 30.4 9.4 6.2 0.1 6.2 5 1 1 6 6 6 0 AN1-like Zinc finger zf-BED PF02892.10 KFP00427.1 - 1.1 9.1 30.6 2.6 7.8 2.0 5.3 1 1 5 6 6 6 0 BED zinc finger zf-ISL3 PF14690.1 KFP00427.1 - 1.2 9.1 36.4 2.9 8.0 0.1 6.1 4 2 2 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C4_Topoisom PF01396.14 KFP00427.1 - 1.9 8.0 18.6 6.5 6.3 0.2 5.3 6 0 0 6 6 5 0 Topoisomerase DNA binding C4 zinc finger Sgf11 PF08209.6 KFP00427.1 - 2.3 7.5 20.3 18 4.7 0.0 6.3 6 1 0 6 6 6 0 Sgf11 (transcriptional regulation protein) Ribosomal_L44 PF00935.14 KFP00427.1 - 3.1 7.8 22.9 8.7 6.4 0.2 5.8 3 3 3 6 6 6 0 Ribosomal protein L44 TF_Zn_Ribbon PF08271.7 KFP00427.1 - 3.2 7.1 28.2 2 7.7 0.3 5.8 5 1 0 5 5 5 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 KFP00427.1 - 3.9 7.0 24.5 11 5.6 0.1 6.0 6 0 0 6 6 6 0 A2L zinc ribbon domain ADK_lid PF05191.9 KFP00427.1 - 6.5 6.5 28.7 13 5.5 0.3 5.9 4 1 1 5 5 5 0 Adenylate kinase, active site lid PhnA_Zn_Ribbon PF08274.7 KFP00427.1 - 7.9 6.3 16.6 28 4.6 0.1 5.6 6 0 0 6 6 6 0 PhnA Zinc-Ribbon TerY-C PF15616.1 KFP00427.1 - 8.6 6.3 25.1 0.053 13.4 1.0 3.8 1 1 3 4 4 4 0 TerY-C metal binding domain WD-3 PF09765.4 KFP00429.1 - 5.5e-109 363.9 0.6 6.3e-109 363.7 0.4 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.3 KFP00429.1 - 1.2e-30 105.2 4.3 2.5e-30 104.2 3.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KFP00429.1 - 6.4e-06 25.8 3.7 1.8e-05 24.4 2.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP00429.1 - 0.00079 19.4 2.2 0.0023 18.0 1.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFP00429.1 - 0.042 13.6 3.6 0.16 11.8 2.5 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KFP00429.1 - 0.27 11.3 2.1 0.55 10.3 1.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 KFP00429.1 - 1 9.4 4.3 0.54 10.3 1.0 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Yae1_N PF09811.4 KFP00431.1 - 1.6e-16 59.5 47.2 1.5e+04 -7.9 32.7 4.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF2216 PF10226.4 KFP00432.1 - 1.3e-99 331.6 13.5 2.7e-99 330.4 8.8 1.9 2 0 0 2 2 2 1 Uncharacterized conserved proteins (DUF2216) DUF605 PF04652.11 KFP00432.1 - 0.023 14.0 8.9 0.028 13.8 6.1 1.2 1 0 0 1 1 1 0 Vta1 like bZIP_1 PF00170.16 KFP00432.1 - 0.078 12.9 12.6 0.53 10.2 0.1 3.4 3 0 0 3 3 3 0 bZIP transcription factor TSC22 PF01166.13 KFP00432.1 - 0.15 12.0 11.3 7.9 6.5 0.1 4.0 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF972 PF06156.8 KFP00432.1 - 5.1 7.4 9.9 26 5.2 0.3 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 KFP00432.1 - 7.4 6.3 9.6 15 5.3 0.3 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain EGF_CA PF07645.10 KFP00433.1 - 1.9e-48 162.1 90.8 3.5e-14 52.5 5.0 8.0 8 0 0 8 8 8 6 Calcium-binding EGF domain cEGF PF12662.2 KFP00433.1 - 3.8e-35 119.1 58.4 1.5e-10 40.4 0.3 7.6 8 0 0 8 8 8 6 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFP00433.1 - 1.5e-10 41.0 53.7 3.2e-07 30.3 4.9 7.8 8 1 0 8 8 8 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFP00433.1 - 2.1e-07 30.7 21.5 6.9e-05 22.7 5.7 8.5 9 1 0 9 9 9 5 EGF-like domain EGF_3 PF12947.2 KFP00433.1 - 9.2e-06 25.5 17.8 3.1e-05 23.8 6.2 7.9 6 3 1 7 7 7 4 EGF domain EGF_MSP1_1 PF12946.2 KFP00433.1 - 0.0032 17.1 41.1 0.11 12.3 0.7 6.5 5 1 1 6 6 6 3 MSP1 EGF domain 1 hEGF PF12661.2 KFP00433.1 - 0.01 15.8 39.3 0.32 11.1 2.1 7.8 7 0 0 7 7 7 0 Human growth factor-like EGF ARL2_Bind_BART PF11527.3 KFP00434.1 - 6.7e-28 96.9 5.4 6.7e-28 96.9 3.7 1.4 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Motilin_assoc PF04643.7 KFP00434.1 - 0.089 12.3 2.1 0.19 11.2 0.3 2.4 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide DSBA PF01323.15 KFP00434.1 - 0.16 11.4 1.0 0.74 9.3 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3347 PF11827.3 KFP00434.1 - 3.9 7.4 5.3 19 5.2 3.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) HOOK PF05622.7 KFP00435.1 - 1.1e-30 106.1 65.9 1.1e-30 106.1 45.7 4.8 1 1 3 4 4 4 2 HOOK protein GAS PF13851.1 KFP00435.1 - 0.00089 18.5 62.7 0.0018 17.4 23.6 12.7 2 1 11 13 13 13 5 Growth-arrest specific micro-tubule binding tRNA_edit PF04073.10 KFP00436.1 - 4.6e-25 87.8 0.0 5.1e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain GTP_EFTU PF00009.22 KFP00437.1 - 4.5e-39 133.8 2.0 4.5e-38 130.5 1.4 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFP00437.1 - 8.7e-30 102.8 1.3 2.7e-29 101.2 0.9 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFP00437.1 - 3.2e-10 39.9 0.1 4.1e-07 30.0 0.0 3.1 3 0 0 3 3 2 2 Elongation factor Tu domain 2 Miro PF08477.8 KFP00437.1 - 1e-07 32.4 1.1 3e-07 30.9 0.0 2.4 2 1 1 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 KFP00437.1 - 4.2e-07 29.9 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KFP00437.1 - 4.9e-05 22.6 0.0 0.00018 20.7 0.0 1.9 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.1 KFP00437.1 - 7.7e-05 22.2 1.2 0.2 11.2 0.2 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 4 Ras PF00071.17 KFP00437.1 - 0.00049 19.5 0.0 0.0016 17.8 0.0 1.9 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP00437.1 - 0.0011 18.1 0.2 0.011 14.9 0.1 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFP00437.1 - 0.0024 17.1 0.1 0.0092 15.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KFP00437.1 - 0.012 15.4 2.9 0.83 9.4 0.0 3.3 2 1 1 3 3 3 0 Dynamin family AAA_26 PF13500.1 KFP00437.1 - 0.18 11.4 1.9 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain IF2_N PF04760.10 KFP00437.1 - 0.18 11.4 4.2 0.17 11.5 0.3 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region ubiquitin PF00240.18 KFP00438.1 - 2e-35 120.0 0.5 3.7e-35 119.1 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KFP00438.1 - 1.6e-28 98.2 4.0 2.9e-28 97.4 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KFP00438.1 - 1.6e-20 72.5 0.4 3.2e-20 71.6 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFP00438.1 - 2e-06 27.9 0.3 9.5e-06 25.7 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KFP00438.1 - 0.00015 21.6 0.7 0.00031 20.6 0.5 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 KFP00438.1 - 0.00029 20.5 0.2 0.00053 19.7 0.0 1.5 1 1 1 2 2 2 1 Telomere stability and silencing DUF2407 PF10302.4 KFP00438.1 - 0.0033 17.5 0.5 0.0046 17.1 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 KFP00438.1 - 0.016 13.5 2.5 0.27 9.5 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2207 PF09972.4 KFP00438.1 - 0.042 12.4 0.5 0.048 12.2 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TUG-UBL1 PF11470.3 KFP00438.1 - 0.043 13.7 0.2 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 GLUT4 regulating protein TUG DUF2870 PF11069.3 KFP00438.1 - 0.064 13.2 0.4 0.13 12.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF4023 PF13215.1 KFP00439.1 - 0.7 9.7 32.5 8.5 6.2 6.1 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4023) WD40 PF00400.27 KFP00440.1 - 1.9e-82 268.4 78.1 3.1e-05 23.6 0.2 29.7 33 0 0 33 33 33 20 WD domain, G-beta repeat HELP PF03451.9 KFP00440.1 - 3.1e-46 154.7 3.0 3.5e-17 61.6 0.0 3.6 3 0 0 3 3 3 3 HELP motif Nucleoporin_N PF08801.6 KFP00440.1 - 1.9e-07 30.1 0.0 0.0051 15.6 0.0 4.4 4 0 0 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KFP00440.1 - 8.1e-05 21.0 9.1 1.8 6.7 0.0 6.3 6 1 1 7 7 7 2 Cytochrome D1 heme domain DUF3312 PF11768.3 KFP00440.1 - 0.00025 19.4 0.0 0.096 10.8 0.0 3.9 4 1 0 4 4 4 1 Protein of unknown function (DUF3312) Apc4_WD40 PF12894.2 KFP00440.1 - 0.00028 20.3 0.0 0.75 9.3 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 KFP00440.1 - 0.00056 19.5 0.1 38 4.1 0.0 5.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KFP00440.1 - 0.00077 17.7 0.0 4.2 5.4 0.0 4.5 4 0 0 4 4 4 1 Nucleoporin Nup120/160 ATP-grasp PF02222.17 KFP00440.1 - 0.072 12.4 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain TruB_C PF09142.6 KFP00440.1 - 0.073 12.7 0.0 19 5.0 0.0 3.7 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Spectrin PF00435.16 KFP00441.1 - 0 1072.8 202.3 5.1e-28 97.4 3.6 18.7 19 0 0 19 19 19 17 Spectrin repeat CH PF00307.26 KFP00441.1 - 1e-42 144.5 7.5 2.5e-23 82.1 0.1 4.3 5 0 0 5 5 5 2 Calponin homology (CH) domain PH_9 PF15410.1 KFP00441.1 - 2.7e-22 79.1 0.7 2e-21 76.3 0.5 2.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFP00441.1 - 2.9e-15 56.3 0.4 2.9e-15 56.3 0.3 2.9 3 0 0 3 3 3 1 PH domain CAMSAP_CH PF11971.3 KFP00441.1 - 5e-11 42.0 0.2 3.5e-08 32.9 0.1 2.9 2 0 0 2 2 2 2 CAMSAP CH domain Acylphosphatase PF00708.13 KFP00442.1 - 6.9e-16 58.1 0.0 7.8e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase DUF3437 PF11919.3 KFP00443.1 - 1e-35 121.3 0.0 4.2e-35 119.3 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KFP00443.1 - 1.5e-05 24.7 0.9 0.51 10.5 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KFP00443.1 - 0.0016 18.7 0.0 2.1 8.6 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats 7tm_1 PF00001.16 KFP00444.1 - 2.7e-21 75.8 8.3 2.7e-21 75.8 5.8 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP00444.1 - 0.62 9.1 18.9 0.011 14.8 8.1 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx LRR_8 PF13855.1 KFP00445.1 - 5.8e-37 125.2 50.5 7.5e-10 38.4 0.6 9.4 5 2 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.2 KFP00445.1 - 9.9e-33 111.2 55.5 6.4e-08 32.0 0.1 11.2 7 3 6 13 13 13 10 Leucine Rich repeats (2 copies) TIR PF01582.15 KFP00445.1 - 3.8e-31 107.4 0.3 7e-31 106.5 0.2 1.4 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.28 KFP00445.1 - 2.9e-22 75.2 48.7 0.16 12.0 0.0 17.2 18 0 0 18 18 18 9 Leucine Rich Repeat TIR_2 PF13676.1 KFP00445.1 - 3.9e-12 46.2 0.0 8.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 KFP00445.1 - 9.1e-06 25.2 48.8 1.5 9.1 0.1 13.6 13 3 3 16 16 16 3 Leucine Rich repeat LRR_7 PF13504.1 KFP00445.1 - 0.00017 21.2 33.8 19 6.0 0.2 13.0 14 0 0 14 14 14 0 Leucine rich repeat LRR_9 PF14580.1 KFP00445.1 - 1.3 8.5 8.1 5.3 6.5 0.1 3.8 3 1 2 5 5 5 0 Leucine-rich repeat ChaC PF04752.7 KFP00446.1 - 2.8e-38 131.6 0.0 3.2e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein Ank_2 PF12796.2 KFP00447.1 - 1.7e-80 265.4 6.8 3.3e-22 78.6 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFP00447.1 - 6.2e-59 193.0 4.0 1.3e-07 31.0 0.0 9.3 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KFP00447.1 - 1.1e-44 149.9 0.2 1.9e-11 44.1 0.0 6.2 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP00447.1 - 2.3e-40 132.5 0.6 3.5e-05 23.6 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 KFP00447.1 - 2.3e-40 135.6 1.5 6.7e-06 26.1 0.0 8.8 1 1 8 9 9 9 9 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFP00447.1 - 3.1e-14 52.5 6.0 6.2e-14 51.5 4.1 1.5 1 0 0 1 1 1 1 SOCS box DUF1394 PF07159.7 KFP00447.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) MARVEL PF01284.18 KFP00448.1 - 7e-12 45.3 10.7 8e-12 45.1 7.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain Col_cuticle_N PF01484.12 KFP00448.1 - 1.5 8.5 7.4 0.3 10.7 0.9 2.4 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Ion_trans PF00520.26 KFP00449.1 - 1.1e-14 54.1 23.4 1.9e-14 53.3 16.2 1.4 1 0 0 1 1 1 1 Ion transport protein Per1 PF04080.8 KFP00449.1 - 2.1 7.6 12.4 0.11 11.9 3.2 2.0 1 1 1 2 2 2 0 Per1-like Ion_trans PF00520.26 KFP00450.1 - 4.5e-12 45.6 4.4 5.9e-12 45.2 3.1 1.2 1 0 0 1 1 1 1 Ion transport protein DUF3139 PF11337.3 KFP00450.1 - 0.0082 16.3 0.8 0.02 15.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3139) PKD_channel PF08016.7 KFP00450.1 - 0.013 13.9 1.4 0.022 13.1 1.0 1.3 1 0 0 1 1 1 0 Polycystin cation channel Med17 PF10156.4 KFP00450.1 - 0.022 13.0 0.5 0.028 12.6 0.4 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Cofilin_ADF PF00241.15 KFP00451.1 - 9.7e-38 128.9 0.3 1.2e-37 128.6 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rib_recp_KP_reg PF05104.7 KFP00452.1 - 5.5e-33 114.6 39.7 5.5e-33 114.6 27.5 4.2 2 2 2 4 4 4 1 Ribosome receptor lysine/proline rich region DUF3899 PF13038.1 KFP00452.1 - 0.39 10.8 7.1 0.086 13.0 0.3 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) MS_channel PF00924.13 KFP00452.1 - 7.9 5.7 6.8 6.2 6.0 0.6 3.1 2 0 0 2 2 2 0 Mechanosensitive ion channel PX PF00787.19 KFP00453.1 - 6e-19 67.9 0.3 6e-19 67.9 0.2 2.6 3 1 0 3 3 3 1 PX domain Vps5 PF09325.5 KFP00453.1 - 3.1e-18 65.8 18.3 1.3e-11 44.1 3.0 2.4 2 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.13 KFP00453.1 - 8.8e-06 25.3 12.7 0.015 14.8 6.8 2.2 2 0 0 2 2 2 2 BAR domain DUF896 PF05979.7 KFP00453.1 - 0.078 12.5 2.8 1.1 8.9 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) NusB PF01029.13 KFP00453.1 - 0.18 11.7 3.8 0.24 11.3 1.4 2.0 2 0 0 2 2 2 0 NusB family PDDEXK_1 PF12705.2 KFP00454.1 - 3.1e-08 33.3 0.0 1.4e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily zf-C2H2 PF00096.21 KFP00455.1 - 1.7e-18 65.7 26.3 6.3e-05 23.0 1.9 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP00455.1 - 3.8e-18 64.8 23.8 1.9e-09 37.3 0.5 5.1 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP00455.1 - 3.7e-16 58.1 22.6 5.6e-05 23.1 1.6 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFP00455.1 - 6.7e-05 22.9 16.2 0.001 19.2 1.7 4.6 3 1 2 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP00455.1 - 0.00015 21.8 18.5 0.1 12.7 0.4 4.0 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFP00455.1 - 0.0082 16.2 12.9 0.068 13.2 2.8 3.7 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFP00455.1 - 0.0099 15.5 1.4 0.0099 15.5 1.0 3.7 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 KFP00455.1 - 0.017 15.0 20.0 12 5.8 13.8 2.6 1 1 0 1 1 1 0 FYVE zinc finger XPA_N PF01286.13 KFP00455.1 - 0.12 12.1 10.7 2.8 7.6 0.0 4.3 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_2 PF12756.2 KFP00455.1 - 0.26 11.4 16.1 1.2 9.2 0.3 3.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) A2L_zn_ribbon PF08792.5 KFP00455.1 - 0.52 9.8 0.1 0.52 9.8 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain ADK_lid PF05191.9 KFP00455.1 - 0.88 9.2 10.8 2.2 8.0 1.7 4.1 3 1 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 KFP00455.1 - 1.1 9.2 17.0 3.5 7.6 0.5 4.6 3 1 1 4 4 4 0 Zinc ribbon domain C1_3 PF07649.7 KFP00455.1 - 1.2 9.2 11.1 9.5 6.3 0.1 4.1 4 0 0 4 4 4 0 C1-like domain zf-H2C2_5 PF13909.1 KFP00455.1 - 3 8.2 24.0 2 8.8 1.6 4.9 4 2 0 4 4 4 0 C2H2-type zinc-finger domain Rubredoxin PF00301.15 KFP00455.1 - 3.2 7.7 7.7 3.9 7.4 0.0 3.6 4 0 0 4 4 4 0 Rubredoxin DUF2225 PF09986.4 KFP00455.1 - 4.1 6.8 8.1 0.44 9.9 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) C1_2 PF03107.11 KFP00455.1 - 6.2 7.0 15.0 30 4.8 0.7 4.5 4 0 0 4 4 4 0 C1 domain DUF3735 PF12537.3 KFP00456.1 - 0.13 12.3 0.3 0.14 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) Acetyltransf_1 PF00583.19 KFP00457.1 - 2.1e-10 40.5 0.1 5.5e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFP00457.1 - 1.1e-09 38.2 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFP00457.1 - 1.6e-09 37.8 0.0 4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFP00457.1 - 5.7e-05 22.8 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFP00457.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNA_pol_Rpc34 PF05158.7 KFP00458.1 - 2.5e-105 352.2 1.1 2.8e-105 352.1 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 KFP00458.1 - 0.00012 21.7 0.8 0.0044 16.7 0.1 3.0 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.6 KFP00458.1 - 0.0032 17.8 2.7 0.4 11.1 0.0 3.4 4 0 0 4 4 4 1 Replication protein A C terminal HTH_24 PF13412.1 KFP00458.1 - 0.019 14.3 0.4 0.064 12.6 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TFIIE_alpha PF02002.12 KFP00458.1 - 0.03 13.8 0.4 0.075 12.5 0.2 1.8 1 0 0 1 1 1 0 TFIIE alpha subunit B-block_TFIIIC PF04182.7 KFP00458.1 - 0.037 13.8 0.2 0.074 12.9 0.2 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_45 PF14947.1 KFP00458.1 - 0.1 12.4 2.4 0.13 12.0 0.5 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix SCPU PF05229.10 KFP00458.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 1 0 1 1 1 0 Spore Coat Protein U domain IPK PF03770.11 KFP00459.1 - 4e-44 150.6 0.0 9.4e-44 149.4 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase ATP-synt_F PF01990.12 KFP00459.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Retrotrans_gag PF03732.12 KFP00459.1 - 0.25 11.4 2.0 1.5 8.9 0.0 2.7 3 1 0 3 3 3 0 Retrotransposon gag protein Presenilin PF01080.12 KFP00460.1 - 1.8e-164 547.3 20.4 1.9e-118 395.8 8.4 2.1 1 1 1 2 2 2 2 Presenilin ABC1 PF03109.11 KFP00461.1 - 5.9e-34 116.5 0.1 2.6e-33 114.5 0.0 2.1 2 0 0 2 2 2 1 ABC1 family DUF2959 PF11172.3 KFP00461.1 - 0.034 13.9 1.2 0.077 12.7 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2959) CNH PF00780.17 KFP00462.1 - 4.3e-70 236.2 0.2 8.1e-70 235.3 0.1 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFP00462.1 - 9.8e-55 185.4 0.0 3.2e-54 183.8 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00462.1 - 1.1e-28 100.0 0.0 3.3e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase DMPK_coil PF08826.5 KFP00462.1 - 2.8e-24 84.7 11.7 2.8e-24 84.7 8.1 9.5 7 4 2 10 10 10 1 DMPK coiled coil domain like C1_1 PF00130.17 KFP00462.1 - 3.1e-11 42.8 7.5 9.4e-11 41.2 5.2 1.9 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFP00462.1 - 1.2e-05 25.7 3.1 3.6e-05 24.1 2.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain PBD PF00786.23 KFP00462.1 - 0.013 15.8 0.4 0.073 13.5 0.3 2.4 1 0 0 1 1 1 0 P21-Rho-binding domain Reo_sigmaC PF04582.7 KFP00462.1 - 1.1 8.4 18.9 1.7 7.7 0.1 3.8 2 2 2 4 4 4 0 Reovirus sigma C capsid protein RVT_1 PF00078.22 KFP00463.1 - 7.6e-23 80.9 0.0 8.8e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3884 PF13024.1 KFP00463.1 - 0.11 11.8 0.1 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) RRM_1 PF00076.17 KFP00464.1 - 1e-24 85.9 0.0 3.4e-15 55.4 0.0 2.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00464.1 - 8.2e-18 64.1 0.0 4.9e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00464.1 - 1.2e-10 41.0 0.0 2e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFP00464.1 - 2.1e-05 24.1 0.0 3.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 DbpA PF03880.10 KFP00464.1 - 0.0073 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 DbpA RNA binding domain KH_1 PF00013.24 KFP00465.1 - 7.2e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFP00465.1 - 2.8e-05 23.6 0.0 6.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 KH domain Scramblase PF03803.10 KFP00466.1 - 7.8e-82 273.6 0.1 8.6e-82 273.4 0.1 1.0 1 0 0 1 1 1 1 Scramblase Scramblase PF03803.10 KFP00467.1 - 2.1e-73 246.0 0.1 2.3e-73 245.9 0.1 1.0 1 0 0 1 1 1 1 Scramblase zf-C2H2 PF00096.21 KFP00468.1 - 3e-13 49.2 9.6 6.5e-06 26.1 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP00468.1 - 1.1e-11 44.2 5.2 0.00068 19.7 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP00468.1 - 6.9e-11 41.8 10.0 6.5e-09 35.6 0.2 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP00468.1 - 0.0009 19.3 1.4 0.28 11.3 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFP00468.1 - 1.2 9.2 8.6 0.78 9.9 1.4 2.8 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KFP00469.1 - 5.4e-23 80.1 30.4 1.5e-08 34.4 0.2 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFP00469.1 - 3.6e-20 71.0 32.0 1.5e-05 25.0 0.1 5.8 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP00469.1 - 1e-17 63.0 21.9 0.0016 18.6 0.1 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP00469.1 - 2.1e-08 34.0 15.2 0.002 18.1 0.2 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP00469.1 - 0.0003 20.8 13.5 0.0033 17.5 0.9 4.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP00469.1 - 0.016 15.0 9.5 0.2 11.5 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger 7tm_1 PF00001.16 KFP00470.1 - 1.2e-61 208.1 23.7 1.5e-61 207.7 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00470.1 - 1.1e-08 34.6 26.5 1.6e-08 34.0 18.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 60KD_IMP PF02096.15 KFP00470.1 - 0.11 12.0 4.3 0.092 12.3 1.8 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein 7TM_GPCR_Srx PF10328.4 KFP00470.1 - 0.32 10.0 34.0 0.48 9.4 21.5 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Peptidase_M14 PF00246.19 KFP00471.1 - 2.1e-84 283.4 0.0 2.7e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFP00471.1 - 2.5e-20 71.9 0.4 5.8e-20 70.7 0.3 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide RRM_1 PF00076.17 KFP00472.1 - 9.2e-17 60.4 0.0 1.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00472.1 - 3e-11 43.1 0.0 4.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00472.1 - 6e-11 42.0 0.0 9.7e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_22 PF03901.12 KFP00473.1 - 1.6e-52 178.9 25.5 2.1e-52 178.5 17.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family GATase_3 PF07685.9 KFP00473.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Transferrin PF00405.12 KFP00474.1 - 2e-228 756.6 8.1 7.6e-120 399.7 0.2 2.0 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.2 KFP00474.1 - 4.3e-17 62.3 0.0 6.4e-08 32.2 0.0 2.7 2 2 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 KFP00474.1 - 0.019 14.2 0.2 7.1 5.8 0.0 3.0 2 1 1 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 Guanylate_kin PF00625.16 KFP00475.1 - 1.1e-64 217.3 1.6 1.7e-64 216.6 1.1 1.3 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.19 KFP00475.1 - 1.7e-63 210.7 8.2 1.6e-20 73.0 0.1 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_assoc PF10600.4 KFP00475.1 - 1.5e-31 108.4 5.4 3.5e-31 107.2 3.7 1.7 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors PDZ_2 PF13180.1 KFP00475.1 - 1.2e-18 66.8 3.4 1.7e-05 24.6 0.1 4.1 4 0 0 4 4 4 3 PDZ domain MAGUK_N_PEST PF10608.4 KFP00475.1 - 9.3e-18 64.4 8.1 3.6e-11 43.3 0.7 2.9 1 1 1 2 2 2 2 Polyubiquitination (PEST) N-terminal domain of MAGUK SH3_1 PF00018.23 KFP00475.1 - 2e-08 33.5 0.1 5.7e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP00475.1 - 2.5e-08 33.2 0.0 6.4e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFP00475.1 - 0.00047 19.6 0.6 0.0023 17.4 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain adh_short PF00106.20 KFP00476.1 - 2.8e-25 89.1 0.0 3.6e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP00476.1 - 2.1e-07 30.7 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFP00476.1 - 1e-06 28.7 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFP00476.1 - 7.9e-06 25.2 0.0 4.6e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KFP00476.1 - 0.021 14.5 0.1 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lipocalin_2 PF08212.7 KFP00477.1 - 3e-22 78.9 0.0 4.1e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 KFP00477.1 - 8.5e-22 77.6 0.1 9.8e-22 77.4 0.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.8 KFP00477.1 - 4.9e-05 23.0 0.3 0.00019 21.0 0.2 1.9 1 1 0 1 1 1 1 Triabin VDE PF07137.6 KFP00477.1 - 0.015 15.1 0.1 0.03 14.1 0.1 1.5 1 1 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) IPP-2 PF04979.9 KFP00478.1 - 1.2e-51 174.4 11.6 1.5e-51 174.0 8.0 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Rrp15p PF07890.7 KFP00478.1 - 0.49 10.4 4.8 0.69 9.9 3.3 1.3 1 0 0 1 1 1 0 Rrp15p Cwf_Cwc_15 PF04889.7 KFP00478.1 - 4.5 6.9 18.0 5.8 6.5 12.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BTV_NS2 PF04514.7 KFP00478.1 - 7 5.4 11.8 11 4.8 8.2 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 ArfGap PF01412.13 KFP00479.1 - 6.2e-40 135.6 0.3 6.2e-40 135.6 0.2 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFP00479.1 - 1.6e-25 89.2 3.7 6.8e-13 48.7 0.1 3.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP00479.1 - 7.8e-14 50.6 0.7 1.6e-05 24.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 KFP00479.1 - 2.9e-13 49.8 0.6 7e-13 48.6 0.4 1.7 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.1 KFP00479.1 - 7.7e-11 41.8 0.3 8.1e-07 29.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP00479.1 - 1.4e-10 41.3 0.2 0.0003 21.2 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP00479.1 - 1.2e-05 25.1 0.8 0.094 13.0 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat PH_11 PF15413.1 KFP00479.1 - 3.2e-05 24.1 8.1 6.4e-05 23.1 1.6 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain Glyco_transf_8 PF01501.15 KFP00480.1 - 6.6e-11 42.0 0.1 7.3e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 PID_2 PF14719.1 KFP00481.1 - 2.4e-54 183.7 6.3 1.2e-35 122.8 1.1 2.1 1 1 1 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) PID PF00640.18 KFP00481.1 - 0.0029 17.5 0.1 0.009 15.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) MMR_HSR1 PF01926.18 KFP00482.1 - 7.9e-16 58.0 0.2 5.1e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP00482.1 - 3.6e-06 26.3 0.1 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KFP00482.1 - 0.00063 18.9 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFP00482.1 - 0.00078 18.6 0.0 0.0019 17.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family cobW PF02492.14 KFP00482.1 - 0.051 13.0 0.3 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KFP00482.1 - 0.065 13.7 0.1 0.42 11.1 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KFP00482.1 - 2.2 8.0 8.0 3 7.6 0.2 3.6 3 1 1 4 4 4 0 Dynamin family E1-E2_ATPase PF00122.15 KFP00483.1 - 5.3e-32 110.7 0.6 5.3e-32 110.7 0.4 2.3 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KFP00483.1 - 1.7e-25 90.2 0.0 4.6e-25 88.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KFP00483.1 - 5.6e-24 84.2 0.3 2e-23 82.4 0.1 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.21 KFP00483.1 - 2.3e-19 70.6 1.2 2.5e-11 44.3 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFP00483.1 - 1.4e-06 27.6 0.0 3.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFP00483.1 - 1.5e-06 28.0 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF342 PF03961.8 KFP00483.1 - 0.057 11.8 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Dynamin_N PF00350.18 KFP00484.1 - 1.2e-36 126.1 0.2 1.2e-36 126.1 0.1 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KFP00484.1 - 2.5e-05 24.2 0.0 0.00014 21.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP00484.1 - 9.2e-05 21.7 0.0 0.0051 16.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 KFP00484.1 - 0.001 19.5 0.1 0.028 14.9 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein DUF1593 PF07632.6 KFP00484.1 - 0.0051 16.1 0.0 0.016 14.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Ras PF00071.17 KFP00484.1 - 0.023 14.1 0.0 7 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.1 KFP00484.1 - 0.067 13.1 1.7 3.5 7.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain GCC2_GCC3 PF07699.8 KFP00484.1 - 0.32 10.5 0.6 0.67 9.5 0.4 1.5 1 0 0 1 1 1 0 GCC2 and GCC3 E1-E2_ATPase PF00122.15 KFP00485.1 - 1.1e-35 122.7 0.1 1.1e-35 122.7 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.3 KFP00485.1 - 1.6e-24 86.0 0.6 4.1e-24 84.7 0.4 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KFP00485.1 - 1.1e-22 81.0 0.0 2.2e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFP00485.1 - 6.7e-17 62.6 0.0 1.3e-15 58.3 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFP00485.1 - 3.1e-06 26.5 0.0 9.7e-06 24.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFP00485.1 - 6.8e-06 25.9 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2620 PF10941.3 KFP00485.1 - 0.018 15.0 0.1 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Endonuc-BglII PF09195.6 KFP00485.1 - 0.086 12.3 0.1 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease BglII E1-E2_ATPase PF00122.15 KFP00486.1 - 3.6e-31 107.9 0.0 8.1e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFP00486.1 - 9.4e-26 91.1 0.0 1.6e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KFP00486.1 - 9.2e-24 83.5 0.8 2.4e-23 82.2 0.6 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.21 KFP00486.1 - 7.7e-18 65.6 0.0 1.2e-12 48.6 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFP00486.1 - 1.8e-07 30.5 0.1 1.6e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KFP00486.1 - 1.5e-06 28.0 0.0 4.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2620 PF10941.3 KFP00486.1 - 0.00045 20.2 0.4 0.0055 16.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function DUF2620 FtsL PF04999.8 KFP00486.1 - 0.098 12.3 0.6 0.32 10.7 0.4 1.8 1 0 0 1 1 1 0 Cell division protein FtsL LRAT PF04970.8 KFP00487.1 - 3.4e-37 127.2 0.0 4e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Calici_PP_N PF08405.6 KFP00487.1 - 0.014 14.2 0.1 0.023 13.5 0.1 1.6 1 1 0 1 1 1 0 Viral polyprotein N-terminal Peptidase_C97 PF05903.9 KFP00487.1 - 0.065 13.0 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Mab-21 PF03281.9 KFP00488.1 - 9.5e-71 238.2 0.5 1.3e-70 237.8 0.3 1.2 1 0 0 1 1 1 1 Mab-21 protein FGF PF00167.13 KFP00489.1 - 6.4e-42 142.1 0.0 8.8e-42 141.7 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFP00489.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Fascin domain CDtoxinA PF03498.9 KFP00489.1 - 0.14 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family CCDC50_N PF15295.1 KFP00491.1 - 5.5e-54 181.6 47.1 1.1e-50 170.9 19.3 2.3 2 1 0 2 2 2 2 Coiled-coil domain-containing protein 50 N-terminus Urotensin_II PF02083.10 KFP00492.1 - 6.6e-05 22.0 4.4 0.00012 21.2 3.1 1.4 1 0 0 1 1 1 1 Urotensin II Musclin PF11037.3 KFP00493.1 - 1.1e-47 160.9 0.4 1.2e-47 160.8 0.2 1.0 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle ANP PF00212.13 KFP00493.1 - 0.00064 19.7 0.1 1.6 8.9 0.0 2.4 2 0 0 2 2 2 2 Atrial natriuretic peptide RBD-FIP PF09457.5 KFP00494.1 - 0.00071 19.3 4.5 0.0013 18.4 3.1 1.4 1 0 0 1 1 1 1 FIP domain DUF3209 PF11483.3 KFP00494.1 - 0.068 13.5 0.3 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DUF1690 PF07956.6 KFP00494.1 - 0.078 12.9 4.2 0.13 12.2 2.9 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) TIR PF01582.15 KFP00495.1 - 5.1e-25 87.5 0.0 9.3e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFP00495.1 - 3.6e-14 52.6 0.3 0.00099 19.1 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP00495.1 - 3.4e-12 46.6 0.9 0.00016 22.1 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFP00495.1 - 1.4e-09 37.7 0.1 0.00071 19.3 0.1 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain TIR_2 PF13676.1 KFP00495.1 - 8.3e-05 22.6 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 TIR domain ig PF00047.20 KFP00495.1 - 9.1e-05 22.5 7.5 0.012 15.7 0.0 4.3 4 1 0 4 4 4 2 Immunoglobulin domain BiPBP_C PF06832.7 KFP00495.1 - 0.041 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family TMEM52 PF14979.1 KFP00496.1 - 4.9e-06 26.5 13.9 0.00021 21.2 9.7 2.1 1 1 0 1 1 1 1 Transmembrane 52 Hum_adeno_E3A PF05393.6 KFP00496.1 - 0.0017 17.9 1.1 0.0027 17.3 0.8 1.3 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein Corona_S2 PF01601.11 KFP00496.1 - 0.71 7.9 6.9 0.86 7.6 4.8 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein WBP-1 PF11669.3 KFP00496.1 - 5.9 7.0 12.0 22 5.2 8.3 1.9 1 1 0 1 1 1 0 WW domain-binding protein 1 PMP22_Claudin PF00822.15 KFP00497.1 - 1.3e-18 67.1 10.0 1.6e-18 66.8 6.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP00497.1 - 7.6e-09 35.4 9.1 1.1e-08 34.9 6.3 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP00498.1 - 6.3e-49 165.8 10.0 7.3e-49 165.6 6.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP00498.1 - 7.2e-11 42.0 9.6 1e-10 41.5 6.7 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 KFP00498.1 - 3.1e-05 23.9 2.3 0.008 16.1 0.4 2.6 2 1 1 3 3 3 2 CD20-like family DUF4134 PF13572.1 KFP00498.1 - 0.026 14.6 2.0 0.058 13.5 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) DUF872 PF05915.7 KFP00498.1 - 0.092 12.6 7.4 0.088 12.6 1.7 2.2 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4282 PF14110.1 KFP00498.1 - 0.12 12.5 7.1 0.25 11.5 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) OppC_N PF12911.2 KFP00498.1 - 0.13 11.6 0.1 0.13 11.6 0.1 2.5 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF981 PF06168.6 KFP00498.1 - 0.17 11.6 6.9 1.4 8.6 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF981) DUF898 PF05987.8 KFP00498.1 - 0.2 10.5 8.6 0.55 9.0 5.9 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) SUR7 PF06687.7 KFP00498.1 - 0.26 10.8 5.5 0.12 11.9 1.7 1.8 1 1 1 2 2 2 0 SUR7/PalI family Cytochrom_B_C PF00032.12 KFP00498.1 - 0.28 11.4 2.8 0.19 11.9 0.4 1.9 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF4131 PF13567.1 KFP00498.1 - 0.32 10.3 0.0 0.32 10.3 0.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4131) HlyIII PF03006.15 KFP00498.1 - 0.46 9.8 4.8 1.2 8.5 3.3 1.8 1 1 0 1 1 1 0 Haemolysin-III related DUF998 PF06197.8 KFP00498.1 - 0.55 9.5 10.7 0.059 12.6 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF373 PF04123.8 KFP00498.1 - 1.3 7.9 4.7 0.57 9.1 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF4064 PF13273.1 KFP00498.1 - 3.4 7.8 13.0 0.32 11.1 0.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) 2OG-FeII_Oxy_3 PF13640.1 KFP00499.1 - 5.3e-15 55.7 0.0 4.1e-14 52.8 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFP00499.1 - 4.9e-05 23.5 0.0 0.00015 22.0 0.0 1.9 2 0 0 2 2 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFP00499.1 - 5.4e-05 22.7 0.1 0.00018 21.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_11 PF13414.1 KFP00499.1 - 0.0018 17.9 3.5 0.22 11.1 0.1 2.9 2 1 1 3 3 3 2 TPR repeat Fis1_TPR_C PF14853.1 KFP00499.1 - 0.0021 17.8 1.2 0.0091 15.8 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 KFP00499.1 - 0.0034 17.8 0.6 0.32 11.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFP00499.1 - 0.009 15.8 7.1 1.3 9.0 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFP00499.1 - 0.0096 15.5 8.0 0.21 11.2 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat YfiO PF13525.1 KFP00499.1 - 0.01 15.3 5.9 0.27 10.6 0.1 3.1 3 0 0 3 3 3 0 Outer membrane lipoprotein Oxygenase-NA PF09859.4 KFP00499.1 - 0.01 15.1 0.0 0.23 10.7 0.0 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA TPR_7 PF13176.1 KFP00499.1 - 0.016 14.9 3.4 3.5 7.6 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFP00499.1 - 0.018 14.8 0.5 0.31 10.9 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFP00499.1 - 0.048 13.6 1.7 2.3 8.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat P53 PF00870.13 KFP00500.1 - 4.9e-108 359.1 2.2 1.5e-107 357.5 0.5 2.1 2 0 0 2 2 2 1 P53 DNA-binding domain P53_tetramer PF07710.6 KFP00500.1 - 2.6e-18 64.8 0.3 6.1e-18 63.6 0.2 1.7 1 0 0 1 1 1 1 P53 tetramerisation motif SAM_2 PF07647.12 KFP00500.1 - 7.4e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LIM PF00412.17 KFP00501.1 - 3.3e-36 123.1 28.2 8e-14 51.4 4.6 3.1 3 0 0 3 3 3 3 LIM domain BTB PF00651.26 KFP00502.1 - 5.8e-27 93.8 0.3 9.8e-27 93.1 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP00502.1 - 1.4e-25 88.2 54.4 1.4e-07 31.4 0.4 7.0 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFP00502.1 - 1.1e-17 63.2 57.8 4.1e-05 23.6 0.2 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-met PF12874.2 KFP00502.1 - 2.4e-11 43.4 32.2 0.0076 16.4 0.1 7.1 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFP00502.1 - 7.2e-11 41.6 59.9 0.011 15.9 0.4 8.0 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP00502.1 - 1e-09 38.2 20.1 0.047 13.8 1.4 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding DUF3342 PF11822.3 KFP00502.1 - 0.0013 17.9 0.3 0.0013 17.9 0.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2_6 PF13912.1 KFP00502.1 - 0.0074 16.1 34.9 0.056 13.3 0.2 6.9 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP00502.1 - 0.18 12.1 0.1 0.18 12.1 0.1 6.5 7 1 0 7 7 7 0 C2H2-type zinc-finger domain GAGA PF09237.6 KFP00502.1 - 0.96 9.0 17.2 5.9 6.5 0.0 5.2 1 1 4 5 5 5 0 GAGA factor Somatostatin PF03002.10 KFP00503.1 - 2e-12 46.3 8.1 2.8e-12 45.9 5.6 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family Trypsin PF00089.21 KFP00504.1 - 3.9e-56 190.0 0.0 5.8e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 KFP00504.1 - 3e-49 165.6 0.8 2.8e-28 98.1 0.1 2.5 2 0 0 2 2 2 2 CUB domain Sushi PF00084.15 KFP00504.1 - 9.8e-14 51.4 18.0 1.4e-07 31.7 0.2 4.3 4 0 0 4 4 4 2 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 KFP00504.1 - 1.4e-08 34.7 11.1 8.4e-08 32.2 5.8 3.0 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site CUB_2 PF02408.15 KFP00504.1 - 6.4e-06 25.7 0.2 0.013 15.0 0.0 2.8 3 0 0 3 3 3 2 CUB-like domain EGF_CA PF07645.10 KFP00504.1 - 2.3e-05 24.2 7.9 2.3e-05 24.2 5.5 2.5 3 0 0 3 3 3 1 Calcium-binding EGF domain Trypsin_2 PF13365.1 KFP00504.1 - 0.00014 21.8 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain cEGF PF12662.2 KFP00504.1 - 0.0041 16.7 3.6 0.0041 16.7 2.5 3.2 3 0 0 3 3 3 1 Complement Clr-like EGF-like V-set PF07686.12 KFP00505.1 - 1.5e-13 50.6 0.1 2.2e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP00505.1 - 0.0003 20.8 0.1 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP00505.1 - 0.00038 20.5 1.6 0.066 13.3 1.1 2.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP00505.1 - 0.00047 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP00505.1 - 1.4 9.5 5.0 5.2 7.6 1.1 3.0 2 1 0 2 2 2 0 Immunoglobulin domain Tctex-1 PF03645.8 KFP00506.1 - 1.7e-13 50.2 0.1 1.9e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family CTP_transf_2 PF01467.21 KFP00507.1 - 5.7e-23 81.6 0.5 9.2e-23 81.0 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase GldM_N PF12081.3 KFP00507.1 - 0.025 14.1 0.4 0.04 13.4 0.3 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Lipoprotein_6 PF01441.14 KFP00507.1 - 0.11 12.3 3.2 0.18 11.6 2.2 1.3 1 0 0 1 1 1 0 Lipoprotein KH_5 PF13184.1 KFP00507.1 - 0.33 10.7 3.2 0.44 10.3 1.3 1.8 2 0 0 2 2 2 0 NusA-like KH domain TFR_dimer PF04253.10 KFP00508.1 - 1.6e-27 95.5 0.0 2.9e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFP00508.1 - 1.3e-12 47.7 0.0 3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFP00508.1 - 7e-06 25.6 0.1 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 PA domain NIDO PF06119.9 KFP00509.1 - 4.8e-10 40.0 0.1 8.8e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Nidogen-like AMOP PF03782.12 KFP00510.1 - 0.011 15.7 3.8 0.059 13.3 2.6 1.9 1 1 0 1 1 1 0 AMOP domain NIDO PF06119.9 KFP00511.1 - 8.9e-10 39.1 0.2 1.7e-09 38.2 0.2 1.5 1 0 0 1 1 1 1 Nidogen-like FAD_binding_7 PF03441.9 KFP00512.1 - 6.7e-39 133.7 2.5 1.1e-37 129.7 1.7 2.1 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFP00512.1 - 1.7e-22 79.8 0.0 3.3e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase DUF4206 PF13901.1 KFP00513.1 - 2.6e-70 236.1 15.6 2.6e-70 236.1 10.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4206) RUN PF02759.14 KFP00513.1 - 5.2e-10 39.1 0.2 1.2e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 RUN domain FYTT PF07078.6 KFP00514.1 - 3.8e-124 414.1 16.4 4.8e-124 413.7 11.4 1.1 1 0 0 1 1 1 1 Forty-two-three protein LRR_4 PF12799.2 KFP00516.1 - 8.3e-25 85.9 17.1 5.7e-07 29.0 0.2 5.8 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP00516.1 - 4.9e-23 80.6 12.8 1e-08 34.7 0.4 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFP00516.1 - 3.3e-17 59.8 24.6 0.044 13.8 0.0 9.2 8 1 0 8 8 8 6 Leucine Rich Repeat CH PF00307.26 KFP00516.1 - 2.5e-10 40.3 0.0 5.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_7 PF13504.1 KFP00516.1 - 1.2e-09 36.8 19.8 0.25 11.7 0.2 8.6 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 KFP00516.1 - 3.6e-06 26.4 14.0 1 9.6 0.3 8.0 8 1 1 9 9 9 1 Leucine Rich repeat CAMSAP_CH PF11971.3 KFP00516.1 - 0.00044 19.8 0.1 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 CAMSAP CH domain LRR_9 PF14580.1 KFP00516.1 - 0.32 10.5 3.7 0.42 10.1 0.5 2.4 2 1 1 3 3 3 0 Leucine-rich repeat Paramyxo_C PF01692.13 KFP00516.1 - 0.77 9.3 7.1 0.44 10.1 0.6 2.4 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c LRR_3 PF07725.7 KFP00516.1 - 8.5 6.3 5.7 4.5 7.2 0.1 3.3 4 0 0 4 4 4 0 Leucine Rich Repeat IQ PF00612.22 KFP00517.1 - 8e-05 21.9 0.3 0.00021 20.6 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ribosomal_L35Ae PF01247.13 KFP00518.1 - 6.4e-43 144.4 0.9 7.1e-43 144.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KFP00518.1 - 0.069 13.0 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain PC_rep PF01851.17 KFP00519.1 - 2.4e-48 159.7 15.9 8.8e-09 35.1 0.0 9.0 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFP00519.1 - 2e-20 72.8 0.6 7.6e-13 48.5 0.0 5.4 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KFP00519.1 - 2.3e-08 33.4 0.3 0.63 10.2 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KFP00519.1 - 2.2e-07 31.1 0.1 0.011 16.1 0.0 4.6 4 1 0 4 4 4 2 HEAT-like repeat HEAT_PBS PF03130.11 KFP00519.1 - 0.0015 18.8 1.6 5.5 7.7 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Tom37_C PF11801.3 KFP00519.1 - 0.14 12.0 4.6 0.33 10.8 3.2 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain Tim54 PF11711.3 KFP00519.1 - 0.15 10.6 7.0 0.24 9.9 4.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PcfK PF14058.1 KFP00519.1 - 2.6 8.1 15.2 6.1 6.9 10.5 1.6 1 0 0 1 1 1 0 PcfK-like protein NARP1 PF12569.3 KFP00519.1 - 3.4 6.3 11.1 7.1 5.2 7.7 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TBX PF12598.3 KFP00519.1 - 3.6 8.0 15.2 0.11 12.9 0.3 2.4 2 0 0 2 2 2 0 T-box transcription factor 7tm_1 PF00001.16 KFP00520.1 - 1.2e-68 231.0 14.1 1.6e-68 230.6 9.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00520.1 - 3.3e-11 42.8 16.2 1e-10 41.2 11.2 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP00520.1 - 7.2e-05 22.0 8.4 7.2e-05 22.0 5.8 2.7 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3930 PF13067.1 KFP00520.1 - 1.5 8.7 5.5 0.3 10.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) HEAT_2 PF13646.1 KFP00521.1 - 0.0051 17.0 0.3 0.038 14.2 0.1 2.4 2 1 0 2 2 2 1 HEAT repeats CENP-B_dimeris PF09026.5 KFP00521.1 - 0.041 14.1 4.4 0.039 14.2 1.3 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1818 PF08848.6 KFP00521.1 - 0.074 13.1 0.6 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) RRM_1 PF00076.17 KFP00522.1 - 1.3e-69 229.7 8.0 2.2e-17 62.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00522.1 - 5.4e-56 186.4 0.8 7.1e-15 54.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00522.1 - 3.4e-30 103.6 0.0 3.7e-08 33.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFP00522.1 - 1.5e-05 24.6 3.6 0.62 9.8 0.0 4.6 3 1 1 4 4 4 2 Limkain b1 DUF4283 PF14111.1 KFP00522.1 - 0.0014 17.7 0.1 0.52 9.3 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4283) DbpA PF03880.10 KFP00522.1 - 0.0034 17.0 0.3 0.71 9.5 0.0 3.7 4 0 0 4 4 4 1 DbpA RNA binding domain Nup35_RRM_2 PF14605.1 KFP00522.1 - 0.0077 15.9 0.0 5.5 6.8 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RSD-2 PF07547.8 KFP00522.1 - 0.079 13.1 0.0 80 3.4 0.0 3.5 3 0 0 3 3 3 0 RSD-2 N-terminal domain SPT16 PF08644.6 KFP00522.1 - 0.58 9.9 6.1 2 8.2 1.2 3.4 2 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) GMP_PDE_delta PF05351.6 KFP00523.1 - 3.2e-44 150.4 0.0 3.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit PQQ PF01011.16 KFP00523.1 - 0.065 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat PCI PF01399.22 KFP00524.1 - 3.8e-12 46.4 3.7 6.7e-12 45.6 0.2 2.2 2 0 0 2 2 2 1 PCI domain Band_3_cyto PF07565.8 KFP00524.1 - 0.2 11.1 7.0 0.47 9.9 4.8 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain RNB PF00773.14 KFP00526.1 - 2.2e-16 60.0 0.1 2.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain Alk_phosphatase PF00245.15 KFP00527.1 - 8.8e-157 522.1 0.5 9.9e-157 521.9 0.3 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KFP00527.1 - 0.0009 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.15 KFP00528.1 - 4.2e-165 549.5 0.0 4.8e-165 549.3 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KFP00528.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Peptidase_M13_N PF05649.8 KFP00529.1 - 1.8e-103 346.6 0.0 2.2e-103 346.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFP00529.1 - 1.6e-63 213.5 0.1 2.6e-63 212.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 AA_permease PF00324.16 KFP00530.1 - 8.4e-21 73.8 6.1 1e-20 73.5 4.2 1.1 1 0 0 1 1 1 1 Amino acid permease Trypsin PF00089.21 KFP00531.1 - 3e-43 147.9 0.0 3.3e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin Neur_chan_LBD PF02931.18 KFP00532.1 - 6e-73 244.5 4.1 8.7e-73 244.0 2.9 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP00532.1 - 1.8e-64 217.8 0.2 2.4e-64 217.4 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region IF4E PF01652.13 KFP00533.1 - 1.2e-61 207.0 0.1 1.6e-61 206.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E p450 PF00067.17 KFP00534.1 - 6.7e-120 400.7 0.0 7.6e-120 400.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFP00535.1 - 3.3e-120 401.7 0.0 3.7e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFP00536.1 - 1e-124 416.6 0.6 1.1e-124 416.4 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mlp PF03304.8 KFP00536.1 - 0.034 14.1 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 Mlp lipoprotein family p450 PF00067.17 KFP00537.1 - 6.7e-122 407.3 0.0 7.6e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFP00538.1 - 1.1e-121 406.6 0.8 1.2e-121 406.4 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 NPH3 PF03000.9 KFP00538.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 NPH3 family Peptidase_C2 PF00648.16 KFP00539.1 - 5.1e-77 258.8 0.1 7.3e-77 258.2 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFP00539.1 - 4.1e-60 201.6 0.0 1.7e-31 108.8 0.0 2.3 2 0 0 2 2 2 2 Calpain large subunit, domain III Peptidase_M1 PF01433.15 KFP00540.1 - 3e-52 178.0 0.0 3.8e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFP00540.1 - 3e-39 133.8 0.1 6.5e-39 132.7 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFP00540.1 - 8.9e-16 58.1 0.0 2.2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2268 PF10026.4 KFP00540.1 - 0.0059 16.0 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) DUF1570 PF07607.6 KFP00540.1 - 0.021 14.7 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) W2 PF02020.13 KFP00541.1 - 2.2e-19 69.1 2.1 2.2e-19 69.1 1.4 3.0 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KFP00541.1 - 9.3e-13 47.0 7.7 0.0002 20.7 0.7 4.2 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFP00541.1 - 0.00072 19.0 6.6 0.22 11.1 0.0 3.9 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Dsh_C PF12316.3 KFP00542.1 - 6.7e-83 277.7 33.2 6.7e-83 277.7 23.0 3.0 2 1 1 3 3 3 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.10 KFP00542.1 - 1e-31 108.9 10.1 1e-31 108.9 7.0 3.5 4 1 0 4 4 4 1 Dishevelled specific domain PDZ PF00595.19 KFP00542.1 - 1.5e-20 73.1 0.3 2.5e-20 72.4 0.2 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DEP PF00610.16 KFP00542.1 - 1.1e-17 63.4 0.1 3e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DIX PF00778.12 KFP00542.1 - 2.3e-07 30.4 0.0 4.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 DIX domain PDZ_2 PF13180.1 KFP00542.1 - 0.0016 18.3 0.1 0.0028 17.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.7 KFP00542.1 - 0.026 13.6 0.1 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region NST1 PF13945.1 KFP00542.1 - 8.5 6.4 13.3 16 5.4 4.9 2.5 3 0 0 3 3 3 0 Salt tolerance down-regulator Adap_comp_sub PF00928.16 KFP00543.1 - 1.3e-84 283.4 0.1 1.6e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFP00543.1 - 5.9e-06 26.0 0.5 9.9e-06 25.3 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KFP00543.1 - 0.043 12.9 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain ABC_tran PF00005.22 KFP00544.1 - 2.5e-43 147.6 0.4 1.9e-20 73.5 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KFP00544.1 - 1.1e-22 79.6 4.6 1.1e-22 79.6 3.2 2.8 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 KFP00544.1 - 5.9e-18 65.8 0.6 0.00024 21.1 0.0 5.1 5 1 1 6 6 5 4 AAA domain SMC_N PF02463.14 KFP00544.1 - 2.5e-13 49.7 0.1 5.9e-05 22.4 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KFP00544.1 - 3.4e-07 30.4 1.6 0.039 14.0 0.0 3.8 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KFP00544.1 - 1e-06 29.5 0.4 0.1 13.4 0.0 3.5 4 0 0 4 4 2 2 AAA domain Miro PF08477.8 KFP00544.1 - 1.8e-06 28.4 0.0 0.086 13.3 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 KFP00544.1 - 1.9e-06 27.6 0.6 0.074 12.6 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_15 PF13175.1 KFP00544.1 - 3.6e-06 26.2 0.4 0.13 11.2 0.1 3.7 3 1 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFP00544.1 - 2.6e-05 23.4 0.1 0.089 11.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 KFP00544.1 - 2.9e-05 24.2 0.8 0.33 11.1 0.0 3.5 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KFP00544.1 - 2.9e-05 23.8 0.2 0.045 13.6 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KFP00544.1 - 4e-05 23.3 0.0 0.37 10.5 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFP00544.1 - 4.7e-05 23.4 3.7 0.13 12.1 0.0 3.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 KFP00544.1 - 7.8e-05 22.1 0.1 0.034 13.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KFP00544.1 - 0.0002 20.9 0.1 1.2 8.5 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 KFP00544.1 - 0.0011 19.3 1.1 0.39 11.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KFP00544.1 - 0.0011 18.8 0.0 0.45 10.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFP00544.1 - 0.0016 18.2 3.7 0.033 14.0 0.0 3.5 2 1 1 3 3 3 1 Dynamin family RNA_helicase PF00910.17 KFP00544.1 - 0.0026 17.9 0.3 0.51 10.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.1 KFP00544.1 - 0.0036 16.7 0.0 0.45 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KFP00544.1 - 0.0058 16.9 15.8 0.2 11.9 0.0 4.0 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 KFP00544.1 - 0.006 16.4 0.5 2.5 8.0 0.0 3.6 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.1 KFP00544.1 - 0.0062 16.4 0.1 5.3 6.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain Septin PF00735.13 KFP00544.1 - 0.0097 14.9 0.0 3.7 6.4 0.0 2.4 2 0 0 2 2 2 1 Septin AAA_30 PF13604.1 KFP00544.1 - 0.012 15.1 1.3 3.6 7.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 KFP00544.1 - 0.014 15.1 10.6 0.3 10.8 0.0 3.9 5 0 0 5 5 4 0 Domain of unknown function DUF87 AAA_28 PF13521.1 KFP00544.1 - 0.015 15.2 0.9 17 5.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 KFP00544.1 - 0.017 14.7 0.0 5.3 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KFP00544.1 - 0.025 14.0 0.0 5.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KFP00544.1 - 0.026 13.3 0.0 0.46 9.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 KFP00544.1 - 0.027 14.1 0.0 8.6 6.0 0.0 2.7 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 KFP00544.1 - 0.028 13.3 0.0 2.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein Arf PF00025.16 KFP00544.1 - 0.042 13.0 0.2 1.5 8.0 0.0 2.8 3 0 0 3 3 3 0 ADP-ribosylation factor family ArgK PF03308.11 KFP00544.1 - 0.047 12.4 0.0 1.7 7.3 0.0 2.3 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 KFP00544.1 - 0.05 13.0 0.1 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 KFP00544.1 - 0.067 12.6 0.1 5 6.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 KFP00544.1 - 0.1 12.0 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PHD PF00628.24 KFP00545.1 - 2.4e-08 33.5 5.6 5.3e-08 32.4 3.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFP00545.1 - 2.4e-07 29.9 2.3 4.8e-07 28.9 1.6 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KFP00545.1 - 0.58 9.9 4.6 0.14 11.8 0.6 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFP00545.1 - 1.1 9.1 4.8 0.21 11.3 0.6 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_M13_N PF05649.8 KFP00547.1 - 8.1e-124 413.6 0.7 1e-123 413.3 0.5 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFP00547.1 - 1.1e-30 106.3 0.5 2.5e-30 105.2 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.13 KFP00547.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M48 PC_rep PF01851.17 KFP00548.1 - 3.3e-27 93.1 17.6 2.6e-06 27.3 0.0 9.1 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFP00548.1 - 0.0004 20.6 0.5 0.33 11.2 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats HSA PF07529.8 KFP00548.1 - 0.16 11.8 2.5 0.19 11.5 0.5 2.0 2 0 0 2 2 2 0 HSA DUF2370 PF10176.4 KFP00548.1 - 0.26 10.5 0.9 0.97 8.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) MIF4G PF02854.14 KFP00549.1 - 2.2e-67 226.5 8.9 2.2e-67 226.5 6.1 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KFP00549.1 - 1.7e-26 92.1 0.2 8.1e-26 89.9 0.1 2.3 2 1 0 2 2 2 1 MA3 domain Condensin2nSMC PF12422.3 KFP00549.1 - 1.4 8.6 3.8 5.3 6.7 0.1 3.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit FAM131 PF15010.1 KFP00550.1 - 5.7e-39 134.6 1.8 8e-39 134.1 1.2 1.2 1 0 0 1 1 1 1 Putative cell signalling CHRD PF07452.7 KFP00551.1 - 1e-09 38.9 0.0 1.2e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 CHRD domain CHRD PF07452.7 KFP00552.1 - 2.1e-62 208.9 0.2 5.9e-27 94.6 0.0 3.1 3 0 0 3 3 3 3 CHRD domain VWC PF00093.13 KFP00552.1 - 0.25 11.4 7.9 0.42 10.7 5.5 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain Amnionless PF14828.1 KFP00552.1 - 2.4 6.5 10.3 3.8 5.9 7.2 1.2 1 0 0 1 1 1 0 Amnionless EPO_TPO PF00758.13 KFP00553.1 - 1.4e-26 93.1 0.7 1.6e-26 92.8 0.5 1.1 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin RNA_pol_Rpb8 PF03870.10 KFP00554.1 - 2.3e-65 218.9 0.2 2.6e-65 218.7 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Pkinase_Tyr PF07714.12 KFP00555.1 - 1.3e-93 312.7 0.0 1.5e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP00555.1 - 5.2e-46 156.8 0.0 6.2e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFP00555.1 - 3.3e-14 53.0 1.1 5.4e-14 52.3 0.8 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Peptidase_C48 PF02902.14 KFP00556.1 - 2.1e-43 148.4 2.3 4.5e-43 147.3 1.6 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DEK_C PF08766.6 KFP00556.1 - 0.00061 19.5 0.0 0.0056 16.4 0.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cystatin PF00031.16 KFP00557.1 - 5.3e-20 71.3 0.0 8e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 Cystatin domain Cystatin PF00031.16 KFP00558.1 - 6.1e-28 96.7 0.0 1.9e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.12 KFP00558.1 - 5.2e-05 23.3 0.0 0.00026 21.0 0.0 2.1 2 0 0 2 2 2 1 Cathelicidin DUF4655 PF15548.1 KFP00558.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) Staphopain_pro PF14731.1 KFP00558.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Staphopain proregion Cystatin PF00031.16 KFP00559.1 - 2.5e-41 139.7 2.3 2.2e-22 79.0 0.5 2.2 2 0 0 2 2 2 2 Cystatin domain Cathelicidins PF00666.12 KFP00559.1 - 6.7e-13 48.5 0.3 1.8e-06 28.0 0.1 2.3 2 0 0 2 2 2 2 Cathelicidin Spp-24 PF07448.6 KFP00559.1 - 0.0002 21.3 1.5 0.0029 17.5 0.4 2.3 2 0 0 2 2 2 1 Secreted phosphoprotein 24 (Spp-24) PTN_MK_C PF01091.13 KFP00559.1 - 0.014 15.3 1.4 0.093 12.7 1.3 2.1 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain DUF3606 PF12244.3 KFP00559.1 - 0.067 12.8 0.1 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) TUG-UBL1 PF11470.3 KFP00559.1 - 0.13 12.1 0.1 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 GLUT4 regulating protein TUG DEAD PF00270.24 KFP00560.1 - 5.8e-42 143.0 1.5 9e-42 142.4 0.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP00560.1 - 1.5e-27 95.2 0.7 4.3e-27 93.7 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFP00560.1 - 0.00012 21.7 0.1 0.00026 20.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KFP00560.1 - 0.00014 21.7 0.1 0.00057 19.7 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFP00560.1 - 0.0035 16.9 0.1 0.0074 15.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFP00560.1 - 0.024 14.7 0.3 0.21 11.7 0.2 2.4 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KFP00560.1 - 0.027 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain tRNA-synt_1b PF00579.20 KFP00560.1 - 0.038 13.1 0.1 0.11 11.5 0.0 1.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 KFP00560.1 - 0.064 13.0 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 KFP00560.1 - 0.088 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA PF00004.24 KFP00561.1 - 1.1e-17 64.4 0.1 5.4e-17 62.2 0.0 2.1 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KFP00561.1 - 6.9e-16 57.9 0.1 1.5e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFP00561.1 - 1.8e-12 47.2 0.1 5.4e-11 42.4 0.0 2.6 2 1 0 2 2 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KFP00561.1 - 3.2e-09 36.0 0.1 8.1e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KFP00561.1 - 2.2e-06 27.3 0.0 5.3e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFP00561.1 - 1.5e-05 25.0 0.0 0.0014 18.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFP00561.1 - 1.6e-05 25.0 0.0 0.00031 20.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFP00561.1 - 5.3e-05 22.9 0.2 0.00012 21.7 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFP00561.1 - 6.9e-05 22.5 0.0 0.00021 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFP00561.1 - 0.00016 21.5 0.0 0.00035 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFP00561.1 - 0.00023 20.1 0.0 0.00055 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KFP00561.1 - 0.00085 18.5 0.1 0.05 12.7 0.0 3.1 3 1 1 4 4 4 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 KFP00561.1 - 0.0015 18.1 1.4 0.0025 17.3 0.1 1.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_24 PF13479.1 KFP00561.1 - 0.0024 17.4 0.1 0.0068 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFP00561.1 - 0.0025 16.8 0.0 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 KFP00561.1 - 0.006 15.5 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KFP00561.1 - 0.01 15.2 0.1 0.29 10.5 0.0 2.8 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 KFP00561.1 - 0.013 15.2 0.3 0.92 9.1 0.0 2.4 1 1 2 3 3 3 0 Archaeal ATPase Viral_helicase1 PF01443.13 KFP00561.1 - 0.016 14.7 0.0 0.54 9.7 0.0 2.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 KFP00561.1 - 0.018 14.7 0.0 0.11 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFP00561.1 - 0.018 13.7 0.0 3 6.4 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus IstB_IS21 PF01695.12 KFP00561.1 - 0.04 13.3 0.1 0.7 9.2 0.0 2.4 2 1 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.24 KFP00561.1 - 0.047 13.1 0.1 1.8 7.9 0.0 2.6 2 1 1 3 3 3 0 DEAD/DEAH box helicase PhoH PF02562.11 KFP00561.1 - 0.062 12.5 0.0 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 KFP00561.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFP00561.1 - 0.13 13.1 0.0 0.31 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain RhoGEF PF00621.15 KFP00562.1 - 1.9e-38 132.1 6.0 1.9e-38 132.1 4.1 2.7 3 1 0 3 3 3 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 KFP00562.1 - 3.4e-15 56.2 0.0 1.2e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.24 KFP00562.1 - 3.1e-07 30.5 0.9 8.7e-07 29.1 0.6 1.8 1 0 0 1 1 1 1 PH domain Spectrin PF00435.16 KFP00562.1 - 8.5e-05 22.7 0.8 8.5e-05 22.7 0.6 4.7 3 1 2 5 5 5 2 Spectrin repeat PH_10 PF15411.1 KFP00562.1 - 0.0017 18.5 0.6 0.0083 16.2 0.4 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain CRAL_TRIO PF00650.15 KFP00562.1 - 0.057 12.8 0.0 0.18 11.2 0.0 1.9 1 0 0 1 1 1 0 CRAL/TRIO domain Galactosyl_T PF01762.16 KFP00563.1 - 1.4e-46 158.5 0.0 2.1e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 KFP00563.1 - 0.00064 19.0 0.0 0.0011 18.1 0.0 1.4 1 1 0 1 1 1 1 Fringe-like Lamp PF01299.12 KFP00565.1 - 5.4e-25 88.1 2.9 5.7e-25 88.0 2.0 1.0 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) CPSase_L_D2 PF02786.12 KFP00566.1 - 1.7e-77 259.4 0.1 3.1e-77 258.6 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KFP00566.1 - 1.5e-45 153.7 0.8 1.3e-44 150.7 0.1 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KFP00566.1 - 1e-36 125.1 0.0 6.5e-36 122.5 0.0 2.3 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KFP00566.1 - 4e-18 65.8 0.3 1.2e-17 64.2 0.1 1.9 2 0 0 2 2 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFP00566.1 - 9.3e-17 60.4 0.4 3.3e-16 58.6 0.3 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KFP00566.1 - 1.1e-16 60.5 0.1 3e-16 59.1 0.1 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFP00566.1 - 8.9e-14 51.3 0.0 3.1e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFP00566.1 - 4.1e-10 39.2 0.3 1.2e-09 37.7 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KFP00566.1 - 1.3e-07 31.2 0.0 3.9e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KFP00566.1 - 6.9e-07 28.8 0.2 0.0009 18.8 0.0 2.9 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.1 KFP00566.1 - 1.6e-06 28.3 0.0 0.058 13.7 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KFP00566.1 - 2.5e-05 24.1 0.1 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KFP00566.1 - 0.00039 20.0 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD PF00529.15 KFP00566.1 - 0.00063 19.1 0.0 0.071 12.4 0.0 2.2 2 0 0 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 KFP00566.1 - 0.015 15.0 0.2 0.054 13.2 0.1 1.9 2 0 0 2 2 1 0 RnfC Barrel sandwich hybrid domain Toxin_59 PF15537.1 KFP00566.1 - 0.033 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative toxin 59 ATPgrasp_ST PF14397.1 KFP00566.1 - 0.052 12.6 0.1 0.34 9.9 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp NQRA PF05896.6 KFP00566.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 KFP00566.1 - 0.062 12.4 0.0 0.69 9.0 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein DUF2118 PF09891.4 KFP00566.1 - 0.11 12.2 0.1 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Cullin_binding PF03556.10 KFP00567.1 - 1.4e-40 138.0 4.7 2.4e-40 137.3 0.7 2.2 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 KFP00567.1 - 5.5e-10 38.6 1.9 1.5e-09 37.2 0.0 2.7 3 0 0 3 3 3 1 UBA-like domain Hydrolase PF00702.21 KFP00568.1 - 1.4e-16 61.5 0.0 6.8e-15 56.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFP00568.1 - 1.5e-16 60.1 0.1 1.5e-16 60.1 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KFP00568.1 - 3.2e-16 60.0 0.0 7.5e-16 58.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP00568.1 - 1.5e-11 44.0 0.0 4.7e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFP00568.1 - 0.00023 20.8 0.0 0.0072 15.9 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FIST_C PF10442.4 KFP00568.1 - 0.094 12.6 0.0 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 FIST C domain SOXp PF12336.3 KFP00570.1 - 2e-29 102.0 4.3 2e-29 102.0 3.0 2.5 3 0 0 3 3 3 1 SOX transcription factor HMG_box PF00505.14 KFP00570.1 - 3.1e-27 94.6 3.2 5.1e-27 93.9 2.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP00570.1 - 1e-11 44.9 1.8 1.9e-11 44.1 1.3 1.4 1 0 0 1 1 1 1 HMG-box domain Tetraspannin PF00335.15 KFP00571.1 - 1.4e-32 112.7 2.9 1.6e-32 112.5 2.0 1.0 1 0 0 1 1 1 1 Tetraspanin family NfeD PF01957.13 KFP00571.1 - 0.006 16.7 0.4 0.0081 16.2 0.3 1.1 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding FtsX PF02687.16 KFP00571.1 - 0.016 14.9 1.6 0.016 14.9 1.1 2.1 1 1 1 2 2 2 0 FtsX-like permease family MARVEL PF01284.18 KFP00571.1 - 0.021 14.6 1.6 0.028 14.2 1.1 1.2 1 0 0 1 1 1 0 Membrane-associating domain SUR7 PF06687.7 KFP00571.1 - 0.022 14.3 2.2 0.031 13.8 1.6 1.2 1 0 0 1 1 1 0 SUR7/PalI family OPT PF03169.10 KFP00571.1 - 0.042 12.2 2.3 0.052 11.9 1.6 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF2976 PF11190.3 KFP00571.1 - 0.072 12.6 0.4 0.072 12.6 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) DUF1628 PF07790.6 KFP00571.1 - 0.22 12.2 0.0 0.22 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) DUF4064 PF13273.1 KFP00571.1 - 0.43 10.7 6.2 15 5.7 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Vma12 PF11712.3 KFP00571.1 - 1.8 8.2 5.1 2.9 7.5 3.6 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2839 PF10999.3 KFP00571.1 - 5.1 7.1 6.6 4.5 7.3 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2839) DUF2892 PF11127.3 KFP00571.1 - 5.8 6.8 6.3 0.5 10.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) Ribosom_S12_S23 PF00164.20 KFP00572.1 - 3.1e-36 123.4 0.6 3.3e-36 123.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UreE_N PF02814.10 KFP00572.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Pkinase PF00069.20 KFP00573.1 - 2.8e-64 216.7 0.0 3.2e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00573.1 - 2.3e-40 138.3 0.0 2.7e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP00573.1 - 1.1e-06 27.8 0.0 1.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP00573.1 - 0.00081 19.1 0.2 0.74 9.4 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP00573.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rad1 PF02144.11 KFP00574.1 - 2.6e-66 223.2 1.1 3e-66 223.0 0.8 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Brix PF04427.13 KFP00575.1 - 1.9e-44 151.6 0.6 3.2e-44 150.8 0.4 1.4 1 0 0 1 1 1 1 Brix domain AcylCoA_DH_N PF12418.3 KFP00575.1 - 0.091 12.4 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal zf-C2H2_jaz PF12171.3 KFP00576.1 - 3.4e-11 42.9 6.8 2.9e-10 39.9 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DnaJ PF00226.26 KFP00576.1 - 4.2e-09 35.9 0.4 2e-08 33.8 0.3 2.3 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 KFP00576.1 - 3e-07 30.3 7.2 6.5e-07 29.3 0.8 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFP00576.1 - 1.4e-06 28.3 3.8 0.022 14.8 0.5 3.1 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KFP00576.1 - 0.84 10.1 6.5 1.5 9.3 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP00576.1 - 1.6 9.2 7.7 8.3 6.9 0.8 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Aminotran_3 PF00202.16 KFP00578.1 - 2.3e-86 289.7 0.0 2.9e-86 289.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KFP00578.1 - 0.00028 19.9 0.0 0.094 11.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II EpoR_lig-bind PF09067.5 KFP00579.1 - 1.8e-46 156.3 0.4 2e-25 88.7 0.0 2.5 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 KFP00579.1 - 3.3e-22 78.4 1.5 8.6e-11 41.8 0.1 3.0 2 0 0 2 2 2 2 Interleukin-6 receptor alpha chain, binding fn3 PF00041.16 KFP00579.1 - 6.7e-17 61.4 10.2 1.6e-06 28.1 0.2 4.8 4 1 0 4 4 4 4 Fibronectin type III domain Tissue_fac PF01108.12 KFP00579.1 - 5.6e-06 26.0 7.4 0.03 14.0 0.0 4.6 4 0 0 4 4 4 2 Tissue factor PKD PF00801.15 KFP00579.1 - 0.001 18.7 2.0 0.69 9.7 0.1 3.2 3 0 0 3 3 3 2 PKD domain NUC130_3NT PF08158.7 KFP00580.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 NUC130/3NT domain Glycophorin_A PF01102.13 KFP00580.1 - 0.12 12.1 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Glycophorin A EF-hand_1 PF00036.27 KFP00581.1 - 2.1e-24 82.9 9.9 7.3e-09 34.3 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KFP00581.1 - 2.3e-21 73.7 10.9 1.5e-06 27.5 0.3 4.5 3 2 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KFP00581.1 - 5.1e-20 71.3 8.2 3.7e-10 39.8 2.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP00581.1 - 3.7e-16 57.6 14.8 3.4e-06 26.1 1.9 5.1 4 2 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 KFP00581.1 - 1.6e-14 53.2 11.7 1.1e-06 28.1 1.0 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 KFP00581.1 - 2.1e-05 24.1 1.6 0.011 15.5 0.1 2.9 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand YugN PF08868.5 KFP00581.1 - 0.04 13.5 0.1 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 YugN-like family EFhand_Ca_insen PF08726.5 KFP00581.1 - 0.044 13.7 0.3 7 6.7 0.0 3.3 3 0 0 3 3 3 0 Ca2+ insensitive EF hand EF-hand_10 PF14788.1 KFP00581.1 - 0.054 13.1 2.2 0.33 10.6 0.7 2.7 3 1 1 4 4 4 0 EF hand SPARC_Ca_bdg PF10591.4 KFP00581.1 - 0.069 13.1 0.3 1.7 8.6 0.0 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 KFP00581.1 - 0.13 11.9 0.0 0.85 9.3 0.0 2.2 2 1 1 3 3 3 0 Tellurite resistance protein TerB LMBR1 PF04791.11 KFP00582.1 - 6.2e-102 341.6 19.9 6.2e-102 341.6 13.8 1.5 2 0 0 2 2 2 1 LMBR1-like membrane protein F-box-like PF12937.2 KFP00583.1 - 3.3e-15 55.5 1.5 1e-14 53.9 1.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFP00583.1 - 1.4e-09 37.3 1.3 1.4e-09 37.3 0.9 2.5 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 KFP00583.1 - 8e-06 25.4 10.4 7.9 6.8 0.0 7.5 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.28 KFP00583.1 - 2.9e-05 23.5 9.7 7.2 7.0 0.0 7.3 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.2 KFP00583.1 - 0.031 13.9 6.4 14 5.4 0.1 4.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP00583.1 - 0.11 12.3 16.1 0.91 9.3 0.1 4.4 4 2 1 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 KFP00583.1 - 0.58 10.5 11.8 37 5.1 0.0 7.1 8 1 0 8 8 8 0 Leucine rich repeat NAD_kinase PF01513.16 KFP00584.1 - 5.4e-09 35.2 0.0 8.9e-07 27.9 0.0 2.4 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.19 KFP00584.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Not3 PF04065.10 KFP00584.1 - 0.16 11.2 0.2 0.27 10.4 0.2 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Ran_BP1 PF00638.13 KFP00585.1 - 3.3e-12 46.5 0.0 6.1e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SDF PF00375.13 KFP00586.1 - 5.6e-137 456.6 32.9 6.5e-137 456.4 22.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MT PF12777.2 KFP00586.1 - 0.012 14.4 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor THP2 PF09432.5 KFP00589.1 - 0.0096 15.7 0.2 0.014 15.2 0.2 1.2 1 0 0 1 1 1 1 Tho complex subunit THP2 Peptidase_C65 PF10275.4 KFP00589.1 - 0.041 13.2 0.4 0.084 12.2 0.1 1.5 1 1 0 1 1 1 0 Peptidase C65 Otubain Nipped-B_C PF12830.2 KFP00589.1 - 0.047 13.3 0.2 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KFP00590.1 - 3.6e-15 55.5 0.3 5.9e-15 54.8 0.2 1.4 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KFP00590.1 - 6.7e-06 25.7 0.4 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.1 KFP00590.1 - 9e-06 26.0 0.4 0.0022 18.4 0.1 1.9 1 1 2 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 KFP00590.1 - 0.0059 16.8 0.1 0.01 16.1 0.1 1.5 1 1 0 1 1 1 1 HEAT repeats Cnd3 PF12719.2 KFP00590.1 - 0.0073 15.3 0.1 0.19 10.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain MMS19_N PF14500.1 KFP00590.1 - 0.06 12.6 0.1 3 7.0 0.0 2.0 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II CcmH PF03918.9 KFP00590.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF3385 PF11865.3 KFP00590.1 - 0.13 12.1 0.0 0.14 12.1 0.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) Nipped-B_C PF12830.2 KFP00591.1 - 2.9e-63 212.9 1.0 2.9e-63 212.9 0.7 2.6 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.1 KFP00591.1 - 1e-05 25.7 0.0 0.023 14.9 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats Joubert PF15392.1 KFP00592.1 - 8.4e-16 58.1 3.0 8.6e-16 58.0 2.1 1.1 1 0 0 1 1 1 1 Joubert syndrome-associated HXXSHH PF07586.6 KFP00595.1 - 0.02 13.8 0.9 0.023 13.6 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Nucleoporin_C PF03177.9 KFP00596.1 - 2.9e-108 362.9 15.4 3.8e-108 362.5 10.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KFP00596.1 - 6.1e-94 315.1 0.0 8.8e-94 314.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 KFP00597.1 - 8.4e-21 73.0 15.8 0.00028 20.6 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat TGF_beta PF00019.15 KFP00598.1 - 4.3e-18 65.5 0.9 6.1e-18 65.0 0.7 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain Hamartin PF04388.7 KFP00598.1 - 0.088 11.4 0.0 0.095 11.3 0.0 1.1 1 0 0 1 1 1 0 Hamartin protein Laminin_G_2 PF02210.19 KFP00599.1 - 9.2e-86 284.3 0.3 1.3e-28 99.6 0.1 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 KFP00599.1 - 7.3e-82 271.8 0.0 4.6e-26 91.3 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain fn3 PF00041.16 KFP00599.1 - 4.1e-22 78.1 0.0 1.7e-11 44.0 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain Laminin_G_3 PF13385.1 KFP00599.1 - 2e-13 50.8 0.4 0.0022 18.2 0.1 3.4 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 KFP00599.1 - 2e-09 37.1 34.9 6.5e-07 29.1 4.9 3.6 3 0 0 3 3 3 2 EGF-like domain Stirrup PF09061.1 KFP00599.1 - 2.9e-07 30.3 0.2 0.031 14.1 0.0 3.4 3 0 0 3 3 3 2 Stirrup hEGF PF12661.2 KFP00599.1 - 0.0059 16.6 17.0 0.12 12.4 0.8 3.7 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.8 KFP00599.1 - 3 8.0 42.5 0.31 11.2 6.7 3.9 3 1 0 3 3 3 0 EGF-like domain fn3 PF00041.16 KFP00600.1 - 2.7e-22 78.6 2.4 4.7e-06 26.6 0.0 6.6 5 1 0 5 5 5 4 Fibronectin type III domain IL6Ra-bind PF09240.5 KFP00600.1 - 6.1e-09 35.9 0.5 0.0038 17.3 0.0 4.1 4 0 0 4 4 4 2 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFP00600.1 - 1.2e-05 25.2 0.3 0.074 13.0 0.1 2.9 2 0 0 2 2 2 2 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFP00601.1 - 2.6e-16 59.5 6.7 0.00024 21.1 0.0 6.0 5 1 0 5 5 5 4 Fibronectin type III domain RICTOR_N PF14664.1 KFP00602.1 - 7.8e-118 393.2 1.5 1.2e-117 392.6 1.0 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KFP00602.1 - 2e-64 216.7 9.2 6.6e-64 215.0 2.5 3.4 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_phospho PF14665.1 KFP00602.1 - 1.4e-49 166.8 1.7 6.5e-49 164.7 1.2 2.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site RasGEF_N_2 PF14663.1 KFP00602.1 - 5.8e-41 139.0 0.2 5.8e-41 139.0 0.1 2.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KFP00602.1 - 7.4e-33 112.3 5.5 9.5e-32 108.7 0.3 3.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 KFP00602.1 - 0.00057 20.1 2.9 0.69 10.2 0.0 4.7 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 KFP00602.1 - 0.09 13.2 2.2 7.4 7.2 0.1 4.3 3 0 0 3 3 3 0 HEAT-like repeat 7TM_GPCR_Srbc PF10316.4 KFP00602.1 - 0.13 11.4 3.0 4.3 6.5 0.0 2.7 2 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srbc hSH3 PF14603.1 KFP00603.1 - 6.7e-27 93.3 14.8 6.3e-22 77.3 0.0 4.3 4 1 0 5 5 5 2 Helically-extended SH3 domain SH3_2 PF07653.12 KFP00603.1 - 1.3e-07 31.0 0.3 4.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFP00603.1 - 0.00029 20.1 0.1 0.21 10.9 0.0 2.6 2 0 0 2 2 2 2 SH3 domain DUF4651 PF15513.1 KFP00603.1 - 0.001 18.4 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4651) SH3_9 PF14604.1 KFP00603.1 - 0.037 13.6 0.3 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain 7tm_1 PF00001.16 KFP00604.1 - 4e-44 150.6 10.7 5e-44 150.3 7.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP00604.1 - 5.3e-08 32.2 15.3 7.4e-08 31.8 10.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srb PF02175.11 KFP00604.1 - 0.0013 18.3 2.1 0.004 16.7 1.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb NdhL PF10716.4 KFP00604.1 - 0.0013 18.4 0.8 0.0042 16.8 0.0 2.2 2 0 0 2 2 2 1 NADH dehydrogenase transmembrane subunit EIIC-GAT PF03611.9 KFP00604.1 - 0.0055 15.5 3.6 0.0092 14.8 0.2 2.1 2 0 0 2 2 2 1 PTS system sugar-specific permease component P22_AR_N PF10547.4 KFP00605.1 - 0.054 13.3 0.5 0.061 13.1 0.4 1.1 1 0 0 1 1 1 0 P22_AR N-terminal domain Herpes_pp85 PF04637.7 KFP00605.1 - 0.16 10.2 1.3 0.16 10.2 0.9 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Nbl1_Borealin_N PF10444.4 KFP00605.1 - 0.19 11.0 2.5 0.23 10.8 0.2 2.2 1 1 1 3 3 3 0 Nbl1 / Borealin N terminal TPR_11 PF13414.1 KFP00606.1 - 3.3e-14 52.2 0.4 5.3e-11 41.9 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFP00606.1 - 9e-10 37.7 0.1 0.00029 20.5 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP00606.1 - 1.1e-08 35.4 1.8 0.0053 17.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP00606.1 - 1.7e-06 28.1 0.6 0.1 13.2 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFP00606.1 - 5.5e-05 22.5 0.0 0.28 10.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP00606.1 - 6.7e-05 23.1 0.1 0.024 14.9 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFP00606.1 - 8.2e-05 22.4 1.9 0.018 15.2 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP00606.1 - 9.5e-05 22.1 0.7 0.2 11.5 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat ChAPs PF09295.5 KFP00606.1 - 0.0019 17.0 0.4 0.0025 16.6 0.3 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 KFP00606.1 - 0.011 15.6 0.2 1.4 8.8 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Vasohibin PF14822.1 KFP00606.1 - 0.045 12.8 0.1 0.073 12.1 0.1 1.3 1 0 0 1 1 1 0 Vasohibin Maf_N PF08383.6 KFP00606.1 - 0.084 12.4 3.0 0.33 10.5 0.0 2.7 3 0 0 3 3 3 0 Maf N-terminal region DUF4107 PF13389.1 KFP00606.1 - 0.16 11.6 1.5 0.35 10.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4107) Pkinase PF00069.20 KFP00607.1 - 7.3e-69 231.7 0.0 1e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00607.1 - 1.9e-37 128.7 0.0 3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP00607.1 - 5.4e-05 22.2 0.0 9.9e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFP00607.1 - 0.0007 18.9 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFP00607.1 - 0.0029 16.6 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP00607.1 - 0.064 12.9 0.2 0.24 11.1 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L37e PF01907.14 KFP00608.1 - 7.9e-25 86.4 15.3 1.3e-24 85.7 10.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KFP00608.1 - 0.0023 17.6 2.4 0.0037 17.0 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon FeS PF04060.8 KFP00608.1 - 0.011 15.3 2.1 0.013 15.0 0.1 2.0 2 0 0 2 2 2 0 Putative Fe-S cluster zf-NADH-PPase PF09297.6 KFP00608.1 - 0.032 13.7 2.5 0.62 9.6 0.0 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain FYDLN_acid PF09538.5 KFP00608.1 - 0.16 12.5 1.4 0.16 12.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GFA PF04828.9 KFP00608.1 - 0.34 10.8 4.1 0.88 9.5 0.3 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 KFP00608.1 - 0.79 9.5 5.9 1.8 8.4 4.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S27a zinc_ribbon_2 PF13240.1 KFP00608.1 - 0.8 9.2 4.3 11 5.5 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2688 PF10892.3 KFP00608.1 - 1 9.0 3.5 6.3 6.5 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) MACPF PF01823.14 KFP00609.1 - 1.7e-47 161.8 1.4 1.7e-47 161.8 1.0 1.7 1 1 1 2 2 2 1 MAC/Perforin domain Sushi PF00084.15 KFP00609.1 - 2.6e-13 50.0 0.9 1.3e-09 38.2 0.2 4.2 4 0 0 4 4 4 2 Sushi domain (SCR repeat) Ldl_recept_a PF00057.13 KFP00609.1 - 7.7e-08 32.1 12.9 7.7e-08 32.1 8.9 3.8 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.14 KFP00609.1 - 9.5e-08 32.0 22.2 1.6e-05 24.8 2.1 5.5 6 0 0 6 6 6 2 Thrombospondin type 1 domain MACPF PF01823.14 KFP00610.1 - 2.6e-46 157.9 2.2 2.6e-46 157.9 1.5 1.7 2 0 0 2 2 2 1 MAC/Perforin domain TSP_1 PF00090.14 KFP00610.1 - 2.3e-13 50.0 41.5 1.5e-08 34.6 5.1 5.3 4 0 0 4 4 4 3 Thrombospondin type 1 domain Sushi PF00084.15 KFP00610.1 - 1.5e-12 47.6 3.6 8.6e-07 29.2 0.2 5.2 5 0 0 5 5 5 2 Sushi domain (SCR repeat) Ldl_recept_a PF00057.13 KFP00610.1 - 1.5e-10 40.7 13.5 1.5e-10 40.7 9.4 4.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A PI-PLC-X PF00388.14 KFP00611.1 - 2.1e-07 30.4 0.0 3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CoA_trans PF01144.18 KFP00612.1 - 6.1e-125 414.5 1.5 2.3e-75 252.4 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KFP00612.1 - 0.0013 18.4 0.1 0.0025 17.4 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain C1-set PF07654.10 KFP00614.1 - 4.6e-26 90.6 0.2 5.4e-26 90.4 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain Marek_A PF02124.10 KFP00614.1 - 0.0052 16.2 0.0 0.0072 15.8 0.0 1.1 1 0 0 1 1 1 1 Marek's disease glycoprotein A ig PF00047.20 KFP00614.1 - 0.0094 16.0 0.2 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.7 KFP00614.1 - 0.018 14.9 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFP00614.1 - 0.027 14.3 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF2273 PF10031.4 KFP00614.1 - 0.074 12.6 3.8 0.11 12.1 2.6 1.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF4505 PF14956.1 KFP00615.1 - 4.4e-59 199.2 0.0 4.9e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) DUF983 PF06170.7 KFP00615.1 - 0.029 14.4 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Histone PF00125.19 KFP00616.1 - 2.1e-13 50.1 0.0 2.5e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFP00616.1 - 0.016 15.2 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFP00617.1 - 3.8e-33 113.4 0.4 5.9e-33 112.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFP00617.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFP00617.1 - 0.011 15.7 0.1 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KFP00617.1 - 0.014 14.6 0.5 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T 5_nucleotid PF05761.9 KFP00618.1 - 2.3e-56 191.2 0.2 3.1e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 KFP00618.1 - 0.0049 17.1 0.3 0.14 12.3 0.0 3.1 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Collagen PF01391.13 KFP00619.1 - 1.4e-68 226.2 289.0 1.5e-08 34.0 23.6 10.3 1 1 7 8 8 8 7 Collagen triple helix repeat (20 copies) C1q PF00386.16 KFP00619.1 - 6.1e-39 132.9 0.1 7.9e-39 132.5 0.0 1.1 1 0 0 1 1 1 1 C1q domain CAP PF00188.21 KFP00620.1 - 5.3e-22 78.6 2.1 7.7e-22 78.0 1.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF3733 PF12534.3 KFP00620.1 - 0.22 10.8 1.7 4.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 LCCL PF03815.14 KFP00621.1 - 2.2e-49 165.4 17.6 4.8e-25 87.3 1.9 3.2 3 0 0 3 3 3 2 LCCL domain CAP PF00188.21 KFP00621.1 - 1.2e-19 71.0 1.2 3e-19 69.7 0.8 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rxt3 PF08642.5 KFP00621.1 - 0.012 15.8 0.0 0.17 12.1 0.0 2.7 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Hormone_recep PF00104.25 KFP00622.1 - 1.7e-39 135.1 0.0 2.4e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP00622.1 - 4.2e-29 100.5 17.0 7.3e-29 99.8 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Foamy_virus_ENV PF03408.9 KFP00622.1 - 0.037 11.5 1.3 0.051 11.1 0.9 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein Pex2_Pex12 PF04757.9 KFP00623.1 - 4e-37 127.8 4.7 6.2e-37 127.2 3.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 KFP00623.1 - 1.9e-08 33.8 9.1 1.9e-08 33.8 6.3 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP00623.1 - 0.002 18.1 10.6 0.002 18.1 7.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP00623.1 - 0.0025 17.6 11.2 0.0055 16.5 7.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KFP00623.1 - 0.0035 16.9 9.6 0.0063 16.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP00623.1 - 0.0037 17.0 8.9 0.0037 17.0 6.2 2.0 2 0 0 2 2 2 1 Ring finger domain RDD PF06271.7 KFP00623.1 - 0.17 11.7 3.3 0.53 10.1 1.2 2.0 1 1 1 2 2 2 0 RDD family zf-RING_6 PF14835.1 KFP00623.1 - 0.77 9.5 5.4 1.1 9.1 2.8 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KFP00623.1 - 1.2 8.9 19.6 0.044 13.5 8.4 2.5 3 0 0 3 3 3 0 zinc-RING finger domain HypA PF01155.14 KFP00623.1 - 2.4 7.9 4.8 12 5.6 3.0 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family PKI PF02827.11 KFP00624.1 - 9.1e-35 118.6 0.9 1e-34 118.4 0.6 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor zf-C2HC_2 PF13913.1 KFP00625.1 - 8e-15 54.0 6.9 7.9e-09 34.9 0.5 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 KFP00625.1 - 0.0075 15.4 4.0 0.0075 15.4 2.8 3.0 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.2 KFP00625.1 - 0.0093 15.7 11.3 0.045 13.5 1.5 3.4 3 0 0 3 3 3 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 KFP00625.1 - 0.02 14.3 5.8 0.02 14.3 4.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Nairovirus_M PF07948.6 KFP00625.1 - 0.03 12.4 0.2 0.047 11.8 0.1 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DUF2321 PF10083.4 KFP00625.1 - 0.047 13.1 0.2 0.15 11.5 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) HypA PF01155.14 KFP00625.1 - 0.13 11.9 9.1 1.8 8.3 1.4 3.1 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C2H2 PF00096.21 KFP00625.1 - 0.68 10.4 0.1 0.68 10.4 0.0 4.2 5 0 0 5 5 3 0 Zinc finger, C2H2 type zinc_ribbon_5 PF13719.1 KFP00625.1 - 1.3 8.6 6.3 9.7 5.8 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFP00625.1 - 1.5 8.6 6.9 12 5.7 0.5 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 KFP00625.1 - 3.8 7.5 8.7 5.6 7.0 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger IL7 PF01415.11 KFP00626.1 - 0.022 14.4 7.9 0.028 14.0 5.5 1.1 1 0 0 1 1 1 0 Interleukin 7/9 family Tweety PF04906.8 KFP00626.1 - 0.025 12.9 0.1 0.031 12.7 0.1 1.0 1 0 0 1 1 1 0 Tweety Stathmin PF00836.14 KFP00627.1 - 1.8e-73 244.7 24.1 2.2e-73 244.5 16.7 1.1 1 0 0 1 1 1 1 Stathmin family HTH_8 PF02954.14 KFP00627.1 - 0.049 13.1 0.7 0.049 13.1 0.5 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family CDC37_N PF03234.9 KFP00627.1 - 0.086 13.1 13.1 0.14 12.4 9.0 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding OS-D PF03392.8 KFP00627.1 - 0.32 10.9 4.6 0.53 10.2 1.9 2.3 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D Fib_alpha PF08702.5 KFP00627.1 - 1.1 9.3 9.7 1.6 8.8 6.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RNA_pol_Rpb1_4 PF05000.12 KFP00627.1 - 1.5 8.6 4.2 0.44 10.3 0.6 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 HLH PF00010.21 KFP00628.1 - 2.9e-17 62.1 0.8 4.7e-17 61.4 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFP00628.1 - 7e-13 48.0 0.0 1.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Hairy Orange MRP-S35 PF10246.4 KFP00629.1 - 1.7e-51 172.5 0.0 2e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 S1 PF00575.18 KFP00629.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain TPD52 PF04201.10 KFP00630.1 - 5.7e-70 234.2 7.7 6.5e-70 234.0 5.4 1.0 1 0 0 1 1 1 1 Tumour protein D52 family PEP-utilisers_N PF05524.8 KFP00630.1 - 0.0021 17.8 2.7 0.0039 16.9 1.9 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal HAUS5 PF14817.1 KFP00630.1 - 0.0039 15.8 2.9 0.005 15.4 2.0 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Occludin_ELL PF07303.8 KFP00630.1 - 0.0064 17.2 3.0 0.2 12.3 0.0 2.2 1 1 1 2 2 2 1 Occludin homology domain Wx5_PLAF3D7 PF09688.5 KFP00630.1 - 0.0078 16.1 1.9 0.013 15.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (Wx5_PLAF3D7) ERM PF00769.14 KFP00630.1 - 0.01 15.4 4.6 0.013 15.0 3.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 KFP00630.1 - 0.018 13.5 8.2 0.075 11.4 0.9 1.9 1 1 0 1 1 1 0 AAA domain DUF4164 PF13747.1 KFP00630.1 - 0.019 15.0 3.4 3.8 7.7 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RsbRD_N PF14361.1 KFP00630.1 - 0.03 14.7 3.5 1.1 9.7 0.2 2.8 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain TBPIP PF07106.8 KFP00630.1 - 0.034 13.7 8.4 0.35 10.4 5.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RNA_pol_A_CTD PF03118.10 KFP00630.1 - 0.039 13.3 1.3 0.099 12.0 0.9 1.7 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain WXG100 PF06013.7 KFP00630.1 - 0.048 13.6 4.7 1.1 9.2 0.2 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG APG6 PF04111.7 KFP00630.1 - 0.065 12.2 4.1 0.083 11.9 2.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 KFP00630.1 - 0.073 13.4 5.8 1.5 9.2 3.8 2.7 2 1 1 3 3 2 0 SlyX MitMem_reg PF13012.1 KFP00630.1 - 0.085 12.9 2.1 0.75 9.9 0.8 2.1 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Apolipoprotein PF01442.13 KFP00630.1 - 0.091 12.2 6.3 0.17 11.3 4.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain VASP_tetra PF08776.6 KFP00630.1 - 0.1 11.9 5.0 0.087 12.1 2.1 1.8 2 0 0 2 2 2 0 VASP tetramerisation domain Cob_adeno_trans PF01923.13 KFP00630.1 - 0.12 12.1 2.7 0.17 11.6 1.8 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase GvpK PF05121.7 KFP00630.1 - 0.13 12.1 3.6 0.44 10.3 2.2 2.0 2 1 0 2 2 1 0 Gas vesicle protein K Talin_middle PF09141.5 KFP00630.1 - 0.14 11.8 3.7 0.15 11.7 2.0 1.4 1 1 0 1 1 1 0 Talin, middle domain V_ATPase_I PF01496.14 KFP00630.1 - 0.16 9.7 3.2 0.19 9.5 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Carbpep_Y_N PF05388.6 KFP00630.1 - 0.19 11.9 1.2 0.4 10.8 0.6 1.7 1 1 0 1 1 1 0 Carboxypeptidase Y pro-peptide Atg14 PF10186.4 KFP00630.1 - 0.22 10.4 3.1 0.29 10.0 2.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Siah-Interact_N PF09032.6 KFP00630.1 - 0.22 11.6 6.5 0.085 12.9 2.0 2.0 1 1 1 2 2 2 0 Siah interacting protein, N terminal IncA PF04156.9 KFP00630.1 - 0.22 11.0 11.7 0.11 12.0 6.3 1.8 1 1 1 2 2 2 0 IncA protein Val_tRNA-synt_C PF10458.4 KFP00630.1 - 0.37 10.8 5.0 0.26 11.3 1.4 2.2 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Ada3 PF10198.4 KFP00630.1 - 0.44 10.3 4.9 0.75 9.5 3.4 1.4 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 HsbA PF12296.3 KFP00630.1 - 0.62 9.9 5.3 0.54 10.1 0.7 2.6 1 1 1 2 2 2 0 Hydrophobic surface binding protein A OmpH PF03938.9 KFP00630.1 - 0.76 9.7 8.8 1.2 9.0 5.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Macoilin PF09726.4 KFP00630.1 - 0.89 7.7 10.5 0.25 9.5 5.2 1.4 1 1 0 1 1 1 0 Transmembrane protein Uds1 PF15456.1 KFP00630.1 - 0.94 9.4 9.0 3.2 7.7 6.2 1.9 1 1 0 1 1 1 0 Up-regulated During Septation Med9 PF07544.8 KFP00630.1 - 1.1 9.0 7.9 0.75 9.5 2.1 2.8 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF724 PF05266.9 KFP00630.1 - 1.1 8.8 7.3 1.5 8.3 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.6 KFP00630.1 - 1.2 7.7 8.3 1.5 7.4 5.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1192 PF06698.6 KFP00630.1 - 1.2 9.0 5.9 3.2 7.6 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) End3 PF12761.2 KFP00630.1 - 1.3 8.6 6.7 0.55 9.8 1.5 2.0 1 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Prefoldin_2 PF01920.15 KFP00630.1 - 1.4 8.7 12.3 1.7 8.4 5.4 2.5 1 1 1 2 2 2 0 Prefoldin subunit Phage_GP20 PF06810.6 KFP00630.1 - 1.6 8.1 8.9 4.2 6.7 6.1 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 KFP00630.1 - 6.6 6.6 18.5 0.064 13.0 5.6 2.8 3 1 0 3 3 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 KFP00630.1 - 7.5 6.6 9.1 4.8 7.2 3.2 2.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BTB PF00651.26 KFP00631.1 - 1e-23 83.4 0.2 1.6e-23 82.7 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP00631.1 - 2.1e-10 40.3 16.3 5.6e-05 23.2 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP00631.1 - 9e-07 28.8 13.2 0.00022 21.3 0.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP00631.1 - 3.4e-06 27.0 15.6 0.0014 18.8 1.2 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF3342 PF11822.3 KFP00631.1 - 1.5e-05 24.3 0.2 1.5e-05 24.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-H2C2_5 PF13909.1 KFP00631.1 - 2.9e-05 24.0 0.7 2.9e-05 24.0 0.5 4.2 4 0 0 4 4 4 1 C2H2-type zinc-finger domain BTB_2 PF02214.17 KFP00631.1 - 0.0046 17.1 0.2 0.0096 16.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-met PF12874.2 KFP00631.1 - 0.22 11.7 11.3 0.31 11.2 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.1 KFP00631.1 - 0.85 9.2 6.0 17 5.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-CHY PF05495.7 KFP00631.1 - 3 8.0 9.9 27 4.9 6.9 2.4 1 1 0 1 1 1 0 CHY zinc finger zf-Di19 PF05605.7 KFP00631.1 - 8.3 6.6 10.7 10 6.2 1.7 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFP00632.1 - 0.021 15.1 0.1 0.079 13.3 0.0 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type MRP_L53 PF10780.4 KFP00634.1 - 1.7e-15 56.7 0.0 2.6e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Lipocalin PF00061.18 KFP00636.1 - 9.8e-21 74.2 1.4 1.1e-20 74.0 1.0 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFP00636.1 - 0.013 15.2 1.4 0.041 13.6 1.0 1.7 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PCNA_N PF00705.13 KFP00636.1 - 0.043 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Lipocalin PF00061.18 KFP00637.1 - 3.9e-24 85.2 0.5 4.2e-24 85.1 0.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFP00637.1 - 4.9e-05 23.0 1.2 8.1e-05 22.3 0.8 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFP00638.1 - 4.8e-26 91.4 3.8 5.3e-26 91.3 2.7 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFP00638.1 - 0.0002 21.1 2.3 0.00026 20.6 1.6 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family tRNA_anti-like PF12869.2 KFP00638.1 - 0.15 11.5 1.6 0.28 10.6 0.2 1.8 1 1 1 2 2 2 0 tRNA_anti-like Inositol_P PF00459.20 KFP00639.1 - 2.7e-83 279.3 0.0 3.3e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family zf-AN1 PF01428.11 KFP00640.1 - 9.7e-20 70.1 23.1 9.3e-11 41.4 7.8 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Snf7 PF03357.16 KFP00641.1 - 3.9e-53 179.3 17.3 5.1e-53 178.9 12.0 1.1 1 0 0 1 1 1 1 Snf7 Trns_repr_metal PF02583.12 KFP00641.1 - 0.17 12.0 2.7 0.23 11.6 1.0 1.8 1 1 1 2 2 2 0 Metal-sensitive transcriptional repressor ScpA_ScpB PF02616.9 KFP00641.1 - 4.6 6.7 13.0 8.5 5.8 9.1 1.5 1 1 0 1 1 1 0 ScpA/B protein PX PF00787.19 KFP00642.1 - 4e-19 68.4 1.0 5.6e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 PX domain DUF641 PF04859.7 KFP00642.1 - 0.015 15.0 0.2 0.048 13.4 0.1 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 KFP00642.1 - 0.44 10.1 5.0 0.88 9.1 3.4 1.5 1 0 0 1 1 1 0 IncA protein SR-25 PF10500.4 KFP00644.1 - 0.0038 16.7 4.3 0.0048 16.4 3.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Muted PF14942.1 KFP00644.1 - 0.0041 17.0 2.8 0.006 16.4 2.0 1.2 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Alpha-2-MRAP_C PF06401.6 KFP00644.1 - 0.018 14.9 1.9 0.025 14.4 1.3 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain RP-C_C PF11800.3 KFP00644.1 - 0.023 14.3 2.5 0.03 14.0 1.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Fmp27_WPPW PF10359.4 KFP00644.1 - 0.053 11.9 1.6 0.06 11.7 1.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.1 KFP00644.1 - 0.056 12.3 2.7 0.066 12.1 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.4 KFP00644.1 - 0.061 13.2 7.0 0.1 12.5 4.9 1.4 1 0 0 1 1 1 0 Haemolysin XhlA MCLC PF05934.6 KFP00644.1 - 0.11 10.7 1.8 0.15 10.2 1.3 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) BUD22 PF09073.5 KFP00644.1 - 0.14 11.2 11.3 0.16 10.9 7.8 1.1 1 0 0 1 1 1 0 BUD22 Gon7 PF08738.5 KFP00644.1 - 0.14 12.1 2.0 0.22 11.5 1.4 1.3 1 0 0 1 1 1 0 Gon7 family Mnd1 PF03962.10 KFP00644.1 - 0.42 10.2 7.1 0.6 9.7 4.9 1.1 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 KFP00644.1 - 0.83 8.6 6.6 1.1 8.3 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4611 PF15387.1 KFP00644.1 - 4.3 7.5 15.5 0.071 13.2 4.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) DUF4614 PF15391.1 KFP00645.1 - 1.2e-18 67.4 0.2 1.5e-18 67.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) Surp PF01805.15 KFP00646.1 - 2.4e-19 68.7 0.9 6.8e-19 67.2 0.6 1.8 1 0 0 1 1 1 1 Surp module G-patch PF01585.18 KFP00646.1 - 2.7e-11 43.0 5.1 5.7e-11 42.0 3.6 1.6 1 0 0 1 1 1 1 G-patch domain CTD_bind PF04818.8 KFP00646.1 - 2.5e-10 40.4 0.2 2.5e-10 40.4 0.2 2.6 2 0 0 2 2 2 1 RNA polymerase II-binding domain. TPT PF03151.11 KFP00647.1 - 1.3e-36 125.5 12.3 1.3e-36 125.5 8.5 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFP00647.1 - 3.8e-11 43.1 17.5 1.9e-05 24.6 5.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KFP00647.1 - 3.1e-05 24.1 12.3 0.00075 19.6 0.7 2.4 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 KFP00647.1 - 0.00017 20.6 19.7 0.00042 19.3 13.7 1.5 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KFP00647.1 - 0.028 13.5 10.5 0.32 10.0 1.6 2.7 1 1 1 2 2 2 0 Nucleotide-sugar transporter DUF4131 PF13567.1 KFP00647.1 - 0.054 12.8 6.2 0.59 9.5 4.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) YwiC PF14256.1 KFP00647.1 - 0.096 12.7 0.4 0.096 12.7 0.3 2.4 1 1 1 2 2 2 0 YwiC-like protein UPF0546 PF10639.4 KFP00647.1 - 0.26 11.1 8.0 1.5 8.6 1.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF1777 PF08648.7 KFP00648.1 - 0.66 9.6 130.8 1.5e+04 -28.7 90.6 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 KFP00648.1 - 9.3 4.5 84.5 11 4.4 58.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2505 PF10698.4 KFP00649.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) TRIC PF05197.8 KFP00651.1 - 2.1e-91 304.7 7.3 2.5e-91 304.4 5.1 1.1 1 0 0 1 1 1 1 TRIC channel DUF788 PF05620.6 KFP00651.1 - 7.6 6.3 7.3 0.79 9.5 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF788) BAR PF03114.13 KFP00652.1 - 1.2e-40 139.5 8.3 1.4e-40 139.2 5.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFP00652.1 - 2.9e-14 52.1 0.1 6.5e-14 51.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP00652.1 - 4.8e-13 48.4 0.1 8.3e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP00652.1 - 1.6e-11 43.5 0.0 3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 KFP00652.1 - 2.1e-08 33.4 6.9 2.7e-08 33.1 4.8 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Exonuc_VII_L PF02601.10 KFP00652.1 - 0.0097 15.1 1.8 0.012 14.8 1.2 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit HAUS5 PF14817.1 KFP00652.1 - 0.036 12.6 2.0 0.046 12.2 1.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF2868 PF11067.3 KFP00652.1 - 0.064 12.4 0.6 0.088 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) MscS_porin PF12795.2 KFP00652.1 - 0.11 11.7 5.5 0.16 11.2 3.6 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2365 PF10157.4 KFP00652.1 - 0.13 12.1 0.5 0.32 10.8 0.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Prefoldin_3 PF13758.1 KFP00652.1 - 0.23 11.2 2.4 0.43 10.3 1.7 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF29 PF01724.11 KFP00652.1 - 0.51 10.1 4.1 0.9 9.3 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 SPRY PF00622.23 KFP00653.1 - 4.9e-14 52.4 0.1 1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.16 KFP00653.1 - 2.5e-07 30.7 0.0 1.5e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain DUF572 PF04502.8 KFP00654.1 - 3.2e-92 309.2 18.5 3.6e-92 309.0 12.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 KFP00654.1 - 0.086 12.7 0.2 1.3 8.8 0.0 2.1 1 1 1 2 2 2 0 Benyvirus 14KDa protein FERM_M PF00373.13 KFP00654.1 - 0.5 10.5 3.2 0.74 10.0 2.2 1.2 1 0 0 1 1 1 0 FERM central domain DUF1436 PF07262.6 KFP00654.1 - 4.1 6.8 7.1 0.36 10.2 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) Autophagy_N PF03986.8 KFP00654.1 - 4.4 7.0 9.2 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain RRM_1 PF00076.17 KFP00655.1 - 4.5e-54 179.9 0.1 3.8e-19 68.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00655.1 - 6.5e-34 115.7 1.0 2.4e-11 43.4 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00655.1 - 5e-22 77.5 0.2 1e-06 28.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M PF11532.3 KFP00655.1 - 5.8e-15 55.0 8.9 1.3e-14 53.9 6.1 1.7 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein M Limkain-b1 PF11608.3 KFP00655.1 - 3.2e-06 26.8 0.3 0.00085 19.0 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 KFP00655.1 - 4.3e-05 23.3 0.3 0.057 13.2 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif DUF3932 PF13068.1 KFP00655.1 - 0.11 12.6 0.0 2.4 8.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) Flagellin_C PF00700.16 KFP00655.1 - 0.26 11.4 0.0 22 5.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Tim44 PF04280.10 KFP00656.1 - 5.7e-40 136.6 0.5 2.5e-39 134.6 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain Prominin PF05478.6 KFP00656.1 - 0.032 11.7 0.9 0.048 11.2 0.6 1.2 1 0 0 1 1 1 0 Prominin SseC PF04888.7 KFP00656.1 - 3.4 6.8 13.5 0.079 12.2 2.2 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family EGF_CA PF07645.10 KFP00657.1 - 0 1025.7 739.8 5.1e-11 42.3 3.5 48.5 50 1 0 50 50 50 44 Calcium-binding EGF domain cEGF PF12662.2 KFP00657.1 - 4.2e-191 617.7 410.2 5.6e-08 32.2 0.1 49.3 49 0 0 49 49 49 43 Complement Clr-like EGF-like EGF PF00008.22 KFP00657.1 - 3.8e-124 403.8 632.8 1.8e-05 24.5 3.5 48.6 46 0 0 46 46 46 43 EGF-like domain TB PF00683.12 KFP00657.1 - 2.5e-117 382.2 131.1 1.6e-14 53.1 4.0 11.1 9 0 0 9 9 9 9 TB domain FXa_inhibition PF14670.1 KFP00657.1 - 3e-107 350.4 697.8 5.1e-08 32.9 8.0 48.2 45 3 3 48 48 48 43 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KFP00657.1 - 3.9e-49 164.2 609.4 2.7e-09 36.8 3.8 48.4 47 0 0 47 47 47 39 EGF domain DUF4279 PF14106.1 KFP00657.1 - 1.2 9.0 0.0 2.3 8.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) MTBP_C PF14920.1 KFP00658.1 - 0.021 14.3 0.5 0.021 14.3 0.3 2.4 1 1 1 2 2 2 0 MDM2-binding FlxA PF14282.1 KFP00658.1 - 0.05 13.5 0.1 0.05 13.5 0.1 3.4 1 1 2 3 3 3 0 FlxA-like protein TBPIP PF07106.8 KFP00658.1 - 0.1 12.1 0.2 0.1 12.1 0.2 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 KFP00658.1 - 0.16 10.4 12.3 0.14 10.5 7.8 1.4 1 1 0 1 1 1 0 AAA domain Nucleo_P87 PF07267.6 KFP00658.1 - 0.2 10.2 6.7 0.25 9.9 4.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Syntaxin_2 PF14523.1 KFP00658.1 - 0.3 11.1 4.7 9.1 6.3 0.5 3.3 1 1 2 3 3 3 0 Syntaxin-like protein TMF_DNA_bd PF12329.3 KFP00658.1 - 0.7 9.7 30.7 0.85 9.4 0.3 5.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 KFP00658.1 - 2.4 7.9 6.2 4.4 7.1 0.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Flagellin_N PF00669.15 KFP00658.1 - 2.4 7.9 15.3 0.11 12.2 1.2 3.1 2 2 2 4 4 4 0 Bacterial flagellin N-terminal helical region DUF724 PF05266.9 KFP00658.1 - 2.5 7.6 22.0 1.7 8.1 0.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Microtub_assoc PF07989.6 KFP00658.1 - 3.5 7.5 10.8 0.69 9.7 1.0 3.6 2 2 1 3 3 3 0 Microtubule associated Fmp27_WPPW PF10359.4 KFP00658.1 - 4.2 5.6 17.0 0.25 9.7 4.3 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Tropomyosin PF00261.15 KFP00658.1 - 4.9 6.1 38.3 1.2 8.1 12.1 3.7 1 1 3 4 4 4 0 Tropomyosin TMCO5 PF14992.1 KFP00658.1 - 5.7 5.9 19.4 8.4 5.4 2.7 2.4 1 1 1 2 2 2 0 TMCO5 family SIR2 PF02146.12 KFP00659.1 - 1.3e-25 90.1 0.0 6.8e-18 65.0 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 KFP00659.1 - 0.00046 19.9 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_1 PF00170.16 KFP00660.1 - 1.5e-12 47.2 13.9 2e-12 46.8 9.1 1.6 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KFP00660.1 - 1.9e-10 40.4 10.2 1.9e-10 40.4 7.1 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 KFP00660.1 - 3.4e-05 24.0 11.5 5.9e-05 23.2 7.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ADIP PF11559.3 KFP00660.1 - 0.014 15.3 11.3 0.02 14.8 7.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mit_KHE1 PF10173.4 KFP00660.1 - 0.031 14.1 0.2 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related V_ATPase_I PF01496.14 KFP00660.1 - 0.19 9.5 5.3 0.25 9.1 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 KFP00660.1 - 0.26 11.0 1.6 0.37 10.5 1.1 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD APG6 PF04111.7 KFP00660.1 - 0.5 9.3 6.5 0.7 8.8 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RNA_polI_A14 PF08203.6 KFP00660.1 - 0.53 10.5 2.9 1 9.6 2.0 1.4 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF1664 PF07889.7 KFP00660.1 - 0.65 9.8 3.2 0.98 9.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 KFP00660.1 - 0.77 9.3 14.0 0.43 10.1 8.3 1.6 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 KFP00660.1 - 1.6 7.6 10.1 2.1 7.1 7.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_BLRF2 PF05812.7 KFP00660.1 - 2.4 7.9 10.6 1.1 9.1 4.5 2.2 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Pkinase PF00069.20 KFP00661.1 - 5e-60 202.8 0.0 6.1e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00661.1 - 2.9e-34 118.3 0.0 1.4e-32 112.8 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFP00661.1 - 0.00052 19.0 0.0 0.001 18.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFP00661.1 - 0.014 15.0 0.0 0.029 14.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFP00661.1 - 0.024 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PINIT PF14324.1 KFP00662.1 - 5.5e-39 133.5 0.9 8.8e-39 132.8 0.6 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFP00662.1 - 2.3e-21 75.0 5.7 5.8e-21 73.7 3.9 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 KFP00662.1 - 1.1e-05 24.8 0.1 5.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 KFP00662.1 - 0.00027 20.3 1.9 0.00027 20.3 1.3 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit GTP_EFTU PF00009.22 KFP00663.1 - 9.6e-61 204.4 0.0 1.3e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFP00663.1 - 1.2e-38 131.3 0.1 3.1e-38 130.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KFP00663.1 - 1.9e-22 78.9 0.0 4.5e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KFP00663.1 - 2.3e-13 49.7 0.0 5.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KFP00663.1 - 1.5e-12 47.4 0.3 1e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFP00663.1 - 1.5e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.20 KFP00664.1 - 2.5e-73 246.4 0.0 2.8e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00664.1 - 2.6e-37 128.3 0.0 3e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFP00664.1 - 2.6e-06 26.6 0.1 5.9e-06 25.4 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP00664.1 - 6.9e-06 25.5 0.1 1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KFP00664.1 - 0.017 14.6 0.2 0.039 13.5 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Glycos_trans_3N PF02885.12 KFP00664.1 - 0.029 13.9 0.0 0.091 12.3 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain YrbL-PhoP_reg PF10707.4 KFP00664.1 - 0.052 12.8 0.1 0.086 12.1 0.1 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL AAA_18 PF13238.1 KFP00665.1 - 4.1e-13 49.7 0.0 9.2e-13 48.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KFP00665.1 - 2.1e-05 25.3 0.0 4.8e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KFP00665.1 - 0.0045 16.5 0.8 0.11 12.0 0.5 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 KFP00665.1 - 0.0061 16.4 0.2 0.029 14.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KFP00665.1 - 0.013 15.3 0.0 0.07 12.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KFP00665.1 - 0.039 13.6 0.1 0.6 9.8 0.0 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KFP00665.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein BNIP2 PF12496.3 KFP00666.1 - 1.1e-40 138.7 0.2 1.5e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CRAL_TRIO_2 PF13716.1 KFP00666.1 - 1.6e-30 105.9 0.1 2.2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFP00666.1 - 1.6e-07 30.9 0.2 2.3e-07 30.4 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain TGF_beta PF00019.15 KFP00667.1 - 3.2e-19 69.1 0.8 4.6e-19 68.6 0.5 1.2 1 0 0 1 1 1 1 Transforming growth factor beta like domain Dus PF01207.12 KFP00668.1 - 4.7e-57 193.1 0.0 6.7e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 KFP00668.1 - 0.0047 16.1 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase zf-CCCH PF00642.19 KFP00668.1 - 0.0071 16.0 15.2 0.032 13.8 0.8 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FMN_dh PF01070.13 KFP00668.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase La PF05383.12 KFP00669.1 - 2e-21 75.5 0.6 2.9e-21 75.0 0.4 1.3 1 0 0 1 1 1 1 La domain RRM_5 PF13893.1 KFP00669.1 - 0.0012 18.6 0.0 0.01 15.6 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP00669.1 - 0.0078 15.8 0.0 1.7 8.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNR_N PF08343.5 KFP00669.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal RFX1_trans_act PF04589.8 KFP00670.1 - 1.8e-56 190.2 17.6 1.8e-56 190.2 12.2 2.9 3 0 0 3 3 3 1 RFX1 transcription activation region RFX_DNA_binding PF02257.10 KFP00670.1 - 4.5e-34 116.4 0.1 2.3e-33 114.1 0.1 2.3 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFP00670.1 - 0.062 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like Fibrinogen_C PF00147.13 KFP00671.1 - 5.5e-63 212.6 0.8 1.2e-62 211.6 0.6 1.6 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DivIC PF04977.10 KFP00671.1 - 0.093 12.2 4.9 0.19 11.2 3.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Ras PF00071.17 KFP00672.1 - 3.1e-63 211.9 0.1 3.7e-63 211.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP00672.1 - 1.1e-20 74.3 0.0 1.7e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP00672.1 - 2.1e-12 46.5 0.1 2.7e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP00672.1 - 9e-08 32.0 0.1 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFP00672.1 - 6.8e-07 29.4 0.1 2.5e-06 27.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KFP00672.1 - 1.4e-05 24.6 0.1 2.6e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP00672.1 - 0.0012 17.9 0.1 0.0024 17.0 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 KFP00672.1 - 0.0027 17.6 0.1 0.0069 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KFP00672.1 - 0.0028 16.7 0.1 0.0044 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFP00672.1 - 0.0034 16.5 0.0 0.0098 15.0 0.0 1.8 2 1 1 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFP00672.1 - 0.0074 16.2 0.5 0.04 13.8 0.2 2.2 1 1 1 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 KFP00672.1 - 0.019 14.1 0.0 0.045 12.9 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KFP00672.1 - 0.025 14.8 0.4 0.042 14.1 0.3 1.8 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 KFP00672.1 - 0.031 13.5 0.2 0.15 11.3 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B YtzH PF14165.1 KFP00672.1 - 0.035 14.3 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 YtzH-like protein PduV-EutP PF10662.4 KFP00672.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KFP00672.1 - 0.12 12.6 0.4 0.83 9.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.1 KFP00672.1 - 0.39 10.6 2.6 0.98 9.3 1.8 1.9 1 1 0 1 1 1 0 AAA domain Vpu PF00558.14 KFP00673.1 - 0.011 15.3 0.4 0.02 14.4 0.2 1.3 1 0 0 1 1 1 0 Vpu protein PRY PF13765.1 KFP00674.1 - 1.6e-20 72.3 0.0 2.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFP00674.1 - 7.1e-13 48.7 0.1 9.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Ran_BP1 PF00638.13 KFP00675.1 - 1.6e-14 53.9 0.4 5.9e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 RanBP1 domain Lon_C PF05362.8 KFP00676.1 - 9.6e-26 90.3 0.0 3.3e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KFP00676.1 - 6.8e-25 87.7 0.0 3.2e-24 85.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KFP00676.1 - 1.1e-23 83.9 8.7 1.1e-23 83.9 6.0 2.6 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KFP00676.1 - 5.3e-09 35.9 0.0 1.7e-08 34.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFP00676.1 - 2.4e-08 34.0 0.0 7.7e-08 32.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFP00676.1 - 2.9e-07 29.7 0.0 1.4e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFP00676.1 - 2.4e-06 27.6 0.2 1.6e-05 25.0 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_PrkA PF08298.6 KFP00676.1 - 2.6e-06 26.3 0.0 5.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KFP00676.1 - 5.2e-06 27.2 0.3 5.5e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFP00676.1 - 5.8e-06 26.4 4.8 0.0001 22.4 0.0 4.2 4 2 0 4 4 4 1 AAA domain AAA_14 PF13173.1 KFP00676.1 - 2.2e-05 24.3 0.3 8.6e-05 22.4 0.0 2.2 3 0 0 3 3 1 1 AAA domain RNA_helicase PF00910.17 KFP00676.1 - 0.0012 18.9 0.0 0.0033 17.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 KFP00676.1 - 0.0028 17.0 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 KFP00676.1 - 0.0043 16.6 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFP00676.1 - 0.0084 15.5 0.0 0.034 13.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 KFP00676.1 - 0.01 15.5 0.3 0.24 11.0 0.0 2.8 2 1 1 3 3 2 0 NTPase AAA_18 PF13238.1 KFP00676.1 - 0.016 15.5 0.0 0.016 15.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.6 KFP00676.1 - 0.017 14.7 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KFP00676.1 - 0.024 14.2 0.0 0.12 11.9 0.0 2.3 1 1 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.20 KFP00676.1 - 0.042 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 KFP00676.1 - 0.046 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 KFP00676.1 - 0.047 13.2 0.1 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 KFP00676.1 - 0.049 13.5 0.1 1.1 9.2 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KFP00676.1 - 0.051 13.8 0.7 0.47 10.7 0.0 2.7 2 1 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 KFP00676.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KFP00676.1 - 0.062 12.1 0.0 0.19 10.6 0.0 1.8 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_21 PF13304.1 KFP00676.1 - 0.064 13.2 0.9 1.8 8.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 KFP00676.1 - 0.068 13.0 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFP00676.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 KFP00676.1 - 0.18 12.0 0.0 0.18 12.0 0.0 3.2 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.1 KFP00676.1 - 2.6 7.5 0.0 2.6 7.5 0.0 3.1 2 2 0 2 2 1 0 AAA domain Lon_C PF05362.8 KFP00677.1 - 1.7e-40 138.5 0.0 1.8e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 KFP00677.1 - 5.5e-09 35.5 0.0 7.2e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Ribosomal_L36e PF01158.13 KFP00678.1 - 2.3e-35 120.4 5.2 2.6e-35 120.3 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Filament PF00038.16 KFP00679.1 - 3e-80 270.0 46.7 4e-80 269.6 32.4 1.2 1 0 0 1 1 1 1 Intermediate filament protein LTD PF00932.14 KFP00679.1 - 5e-20 71.7 0.5 9.6e-20 70.7 0.4 1.4 1 0 0 1 1 1 1 Lamin Tail Domain Myosin_tail_1 PF01576.14 KFP00679.1 - 9.6e-05 20.3 58.2 0.044 11.5 40.5 3.3 1 1 0 1 1 1 1 Myosin tail BRE1 PF08647.6 KFP00679.1 - 0.0016 18.3 7.8 0.0016 18.3 5.4 3.8 2 1 0 3 3 3 1 BRE1 E3 ubiquitin ligase IncA PF04156.9 KFP00679.1 - 0.0032 17.0 10.5 0.0032 17.0 7.3 3.4 1 1 2 3 3 3 2 IncA protein CagE_TrbE_VirB PF03135.9 KFP00679.1 - 0.021 14.5 0.5 0.021 14.5 0.4 1.8 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system DUF972 PF06156.8 KFP00679.1 - 0.082 13.2 0.5 0.082 13.2 0.3 5.2 1 1 3 4 4 4 0 Protein of unknown function (DUF972) PspB PF06667.7 KFP00679.1 - 0.28 11.1 3.6 0.25 11.2 0.4 2.7 2 0 0 2 2 2 0 Phage shock protein B M PF02370.11 KFP00679.1 - 3.5 8.2 14.6 1.2 9.6 2.3 4.8 3 0 0 3 3 3 0 M protein repeat zf-Tim10_DDP PF02953.10 KFP00680.1 - 1.8e-19 68.8 0.9 2e-19 68.6 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TIL PF01826.12 KFP00680.1 - 0.21 11.7 1.0 0.27 11.3 0.7 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Trypsin PF00089.21 KFP00681.1 - 3.3e-64 216.4 0.0 3.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP00681.1 - 3.8e-09 36.2 0.0 5.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.21 KFP00682.1 - 2.9e-69 233.0 0.0 3.2e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP00682.1 - 6.7e-05 22.3 0.0 8.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Peptidase_A22B PF04258.8 KFP00683.1 - 5.2e-89 298.6 16.2 7.4e-89 298.1 11.2 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.17 KFP00683.1 - 3.8e-13 48.9 0.0 8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 PA domain Presenilin PF01080.12 KFP00683.1 - 0.043 12.6 16.8 0.039 12.7 2.7 2.8 3 1 0 3 3 3 0 Presenilin DUF4064 PF13273.1 KFP00683.1 - 0.052 13.6 2.6 0.26 11.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4191 PF13829.1 KFP00683.1 - 0.4 9.7 0.0 0.4 9.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) LSM PF01423.17 KFP00684.1 - 1.6e-18 66.0 0.0 1.9e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain Kelch_1 PF01344.20 KFP00685.1 - 7.5e-23 79.8 16.7 2e-05 24.0 0.6 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFP00685.1 - 2.5e-21 74.8 12.2 0.00013 21.9 0.1 6.4 4 2 2 6 6 6 6 Kelch motif BACK PF07707.10 KFP00685.1 - 4.6e-21 74.5 1.5 1.7e-20 72.7 0.3 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.1 KFP00685.1 - 1.6e-08 34.3 6.3 0.26 11.2 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KFP00685.1 - 1.5e-07 30.9 9.6 0.071 12.9 0.1 5.9 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 KFP00685.1 - 1.3e-06 28.4 6.1 0.00057 19.9 0.1 5.2 6 0 0 6 6 6 1 Galactose oxidase, central domain BTB PF00651.26 KFP00685.1 - 2.6e-06 27.4 0.1 4.1e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 KFP00685.1 - 8.7e-06 25.4 17.9 0.021 14.5 0.1 6.8 6 2 1 7 7 7 2 Galactose oxidase, central domain DUF1668 PF07893.8 KFP00685.1 - 0.08 12.0 0.1 0.66 9.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) TRAM_LAG1_CLN8 PF03798.11 KFP00686.1 - 5.4e-34 117.4 29.3 6.9e-34 117.1 20.3 1.1 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 KFP00686.1 - 1e-06 28.2 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP00686.1 - 0.00077 18.4 1.0 0.0011 17.9 0.0 1.7 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFP00686.1 - 0.049 13.3 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Tmemb_9 PF05434.6 KFP00686.1 - 0.45 10.2 2.0 0.4 10.4 0.1 1.8 1 1 1 2 2 2 0 TMEM9 SEA PF01390.15 KFP00687.1 - 3.8e-68 225.9 6.9 1.7e-14 53.3 0.0 5.3 5 0 0 5 5 5 5 SEA domain DUF2205 PF10224.4 KFP00687.1 - 6.4e-05 22.4 0.0 3.1 7.4 0.0 3.6 3 0 0 3 3 3 3 Predicted coiled-coil protein (DUF2205) Peptidase_S64 PF08192.6 KFP00687.1 - 0.026 12.8 6.1 1.1 7.4 0.0 3.4 3 1 0 4 4 4 0 Peptidase family S64 DUF1049 PF06305.6 KFP00687.1 - 0.082 12.3 3.3 0.16 11.4 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) UPF0560 PF10577.4 KFP00687.1 - 0.13 10.4 0.3 0.2 9.8 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RRM_1 PF00076.17 KFP00688.1 - 9.4e-21 73.2 0.0 2.5e-10 39.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00688.1 - 7.3e-15 54.7 0.1 9.9e-09 35.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00688.1 - 1.5e-11 43.9 0.0 0.0014 18.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KFP00688.1 - 0.045 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Nop10p PF04135.7 KFP00689.1 - 1.1e-20 73.0 0.2 1.3e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family zf-RING_2 PF13639.1 KFP00690.1 - 3e-06 26.9 2.0 5.8e-06 26.0 1.4 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 KFP00690.1 - 0.0022 17.6 1.2 0.0034 17.0 0.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.20 KFP00690.1 - 0.0029 17.2 2.8 0.0056 16.3 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Orthoreo_P10 PF07204.6 KFP00690.1 - 0.022 14.4 0.6 0.032 13.9 0.4 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 zf-RING_5 PF14634.1 KFP00690.1 - 0.027 14.2 2.2 0.044 13.5 1.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF1301 PF06979.7 KFP00690.1 - 0.075 13.1 0.2 0.09 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) zf-C3HC4_3 PF13920.1 KFP00690.1 - 0.1 12.2 2.1 0.17 11.5 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP00690.1 - 0.35 11.0 2.7 0.61 10.2 1.8 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFP00690.1 - 0.99 9.4 6.0 0.12 12.4 1.3 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fumble PF03630.9 KFP00691.1 - 2.4e-142 473.7 0.0 2.8e-142 473.6 0.0 1.0 1 0 0 1 1 1 1 Fumble Y_phosphatase PF00102.22 KFP00693.1 - 3.3e-57 193.5 2.6 4.5e-57 193.0 1.8 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rifin_STEVOR PF02009.11 KFP00693.1 - 0.0043 16.7 0.1 0.0095 15.6 0.0 1.5 2 0 0 2 2 2 1 Rifin/stevor family DUF2207 PF09972.4 KFP00693.1 - 0.0054 15.3 0.0 0.0087 14.7 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) EphA2_TM PF14575.1 KFP00693.1 - 0.012 16.0 0.1 0.039 14.3 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.1 KFP00693.1 - 0.015 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.7 KFP00693.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.1 KFP00693.1 - 0.022 14.4 9.5 0.13 11.9 6.6 2.2 1 1 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.7 KFP00693.1 - 0.031 14.3 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3149 PF11346.3 KFP00693.1 - 0.19 11.3 2.5 0.42 10.2 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Herpes_BLLF1 PF05109.8 KFP00693.1 - 1.6 6.5 28.6 2 6.2 19.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RVT_1 PF00078.22 KFP00694.1 - 6.6e-15 55.0 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFP00694.1 - 1.1e-13 50.5 0.6 1.7e-13 49.9 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain ARA70 PF12489.3 KFP00694.1 - 0.079 12.9 0.5 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Nuclear coactivator PGK PF00162.14 KFP00696.1 - 2.3e-141 470.7 0.6 2.7e-141 470.5 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Yae1_N PF09811.4 KFP00697.1 - 2.5e-20 71.7 47.7 1.5e+04 -10.9 33.1 5.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal TRP_2 PF08344.6 KFP00698.1 - 2e-30 104.4 1.0 4.5e-30 103.3 0.7 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ion_trans PF00520.26 KFP00698.1 - 3e-30 104.9 10.3 5.2e-30 104.2 7.1 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.2 KFP00698.1 - 5.8e-13 48.9 1.0 4.6e-06 26.8 0.3 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP00698.1 - 1.3e-09 38.3 0.0 0.00035 20.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP00698.1 - 1.7e-08 33.8 1.4 0.00086 19.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFP00698.1 - 5.8e-06 26.0 5.7 0.058 13.6 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 KFP00698.1 - 1.9e-05 24.7 0.0 0.19 12.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.7 KFP00698.1 - 0.0002 19.9 13.2 0.04 12.3 1.5 2.8 2 1 0 2 2 2 2 Polycystin cation channel Glyco_tran_28_C PF04101.11 KFP00699.1 - 1e-21 77.3 0.0 1.1e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFP00699.1 - 3.9e-05 22.9 0.0 4.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 DCX PF03607.12 KFP00700.1 - 9.3e-47 156.4 0.2 7.2e-24 83.1 0.0 2.3 2 0 0 2 2 2 2 Doublecortin Yae1_N PF09811.4 KFP00701.1 - 0.02 14.4 47.3 2 8.0 2.1 5.3 1 1 2 3 3 3 0 Essential protein Yae1, N terminal Pkinase PF00069.20 KFP00702.1 - 1.8e-72 243.6 0.0 3.1e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00702.1 - 1.9e-45 154.9 0.0 2.9e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFP00702.1 - 1.2e-22 80.0 0.2 3.3e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KFP00702.1 - 2.9e-08 33.0 0.0 9e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFP00702.1 - 0.0012 18.6 0.0 0.012 15.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.7 KFP00702.1 - 0.0032 16.7 0.0 0.0074 15.5 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Kdo PF06293.9 KFP00702.1 - 0.14 11.2 0.0 0.31 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_60s PF00428.14 KFP00702.1 - 9.2 6.7 9.7 1.1 9.7 0.4 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein VWC PF00093.13 KFP00703.1 - 1.4e-26 92.3 61.0 8.8e-10 38.5 7.1 3.8 4 0 0 4 4 4 3 von Willebrand factor type C domain DUF1496 PF07383.7 KFP00703.1 - 0.00026 20.1 0.2 0.33 10.2 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1496) AMMECR1 PF01871.12 KFP00704.1 - 3.8e-44 149.8 0.0 4.5e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 TMEM164 PF14808.1 KFP00705.1 - 3.9e-120 399.6 11.4 4.5e-120 399.4 7.9 1.0 1 0 0 1 1 1 1 TMEM164 family DUF2768 PF10966.3 KFP00705.1 - 0.61 10.2 4.4 27 5.0 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) AMP-binding PF00501.23 KFP00706.1 - 1.2e-98 330.3 0.0 1.4e-98 330.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFP00706.1 - 0.00013 22.8 0.0 0.0013 19.6 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ISK_Channel PF02060.10 KFP00707.1 - 8.4e-12 44.7 0.0 8.7e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel NTF2 PF02136.15 KFP00708.1 - 1.7e-29 102.6 0.4 1.9e-29 102.3 0.3 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KFP00708.1 - 0.00013 21.7 0.1 0.00016 21.5 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SnoaL_2 PF12680.2 KFP00708.1 - 0.04 14.3 0.0 0.053 13.9 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain C4 PF01413.14 KFP00709.1 - 1.5e-75 250.4 7.4 2e-50 169.4 0.5 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Peptidase_C54 PF03416.14 KFP00710.1 - 8e-113 376.2 0.0 9.6e-113 375.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ank_2 PF12796.2 KFP00711.1 - 3.1e-56 187.6 7.6 1.2e-20 73.5 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP00711.1 - 2.3e-53 175.4 6.6 6.2e-11 41.5 0.1 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KFP00711.1 - 3.9e-48 160.3 10.5 7.7e-11 41.8 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP00711.1 - 7.1e-46 153.8 7.0 7.5e-13 48.6 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP00711.1 - 6.7e-41 134.2 2.2 1.5e-07 30.9 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ras PF00071.17 KFP00712.1 - 1.2e-29 102.7 0.1 1.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP00712.1 - 0.0064 16.9 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein CENP-M PF11111.3 KFP00712.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Prefoldin PF02996.12 KFP00713.1 - 6.5e-37 125.8 0.3 9.8e-37 125.2 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KFP00713.1 - 7.4e-05 22.4 5.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 2 Prefoldin subunit MRL1 PF13003.2 KFP00713.1 - 0.05 13.4 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L1 FlgN PF05130.7 KFP00713.1 - 0.064 13.4 3.1 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 FlgN protein CENP-Q PF13094.1 KFP00713.1 - 0.35 10.8 5.7 3.9 7.4 0.2 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HR1 PF02185.11 KFP00713.1 - 4.6 7.0 9.9 0.43 10.3 0.1 2.5 3 0 0 3 3 3 0 Hr1 repeat ANTH PF07651.11 KFP00714.1 - 1.7e-69 233.6 1.5 2.7e-69 233.0 1.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KFP00714.1 - 5.8e-07 29.4 0.1 1.5e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 ENTH domain CHDCT2 PF08074.6 KFP00714.1 - 0.11 12.2 0.6 0.2 11.3 0.5 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain GST_N_3 PF13417.1 KFP00714.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF3824 PF12868.2 KFP00714.1 - 2.2 9.2 4.3 0.4 11.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) T2SM PF04612.7 KFP00714.1 - 2.9 7.6 7.1 3.8 7.2 3.8 1.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M SNF2_N PF00176.18 KFP00715.1 - 4.7e-86 288.2 0.2 7.7e-86 287.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KFP00715.1 - 3.9e-44 149.1 5.5 4.3e-44 149.0 2.2 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 KFP00715.1 - 7e-27 94.0 2.0 7e-27 94.0 1.4 3.4 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 KFP00715.1 - 3.2e-18 65.3 0.0 2.1e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP00715.1 - 2.1e-08 34.2 1.1 1e-06 28.6 0.0 4.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFP00715.1 - 5.3e-08 32.5 0.0 3.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.1 KFP00715.1 - 3.4e-05 23.8 0.1 3.4e-05 23.8 0.1 5.1 6 0 0 6 6 6 1 DNA-binding domain Myb_DNA-binding PF00249.26 KFP00715.1 - 0.00063 19.7 0.0 0.72 9.9 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Tom37_C PF11801.3 KFP00715.1 - 0.1 12.4 2.6 0.15 11.9 0.3 2.4 2 0 0 2 2 2 0 Tom37 C-terminal domain Yae1_N PF09811.4 KFP00716.1 - 1.8e-13 49.7 51.5 6.2e+03 -3.2 0.0 5.3 2 1 0 2 2 2 0 Essential protein Yae1, N terminal Tox-GHH PF15636.1 KFP00717.1 - 2.5e-30 103.9 1.2 5.1e-30 102.9 0.8 1.6 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin Ten_N PF06484.7 KFP00717.1 - 6.2e-22 78.2 7.3 9.2e-22 77.6 5.1 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region EGF_2 PF07974.8 KFP00717.1 - 6.9e-13 48.5 171.1 0.00045 20.3 8.3 9.8 9 1 1 10 10 10 7 EGF-like domain NHL PF01436.16 KFP00717.1 - 3.2e-12 45.7 0.2 0.071 13.1 0.0 7.1 6 0 0 6 6 6 3 NHL repeat hEGF PF12661.2 KFP00717.1 - 1.1e-05 25.1 79.1 0.0047 16.9 2.4 9.3 8 0 0 8 8 8 6 Human growth factor-like EGF RHS_repeat PF05593.9 KFP00717.1 - 3.2e-05 23.9 32.3 0.013 15.6 0.4 7.9 8 2 1 9 9 9 3 RHS Repeat RHS PF03527.9 KFP00717.1 - 0.0002 21.0 0.3 0.0083 15.8 0.0 2.8 2 0 0 2 2 2 1 RHS protein SGL PF08450.7 KFP00717.1 - 0.00033 20.0 0.1 0.67 9.2 0.0 3.7 3 1 1 4 4 4 2 SMP-30/Gluconolaconase/LRE-like region CarboxypepD_reg PF13620.1 KFP00717.1 - 0.00078 19.4 0.1 0.0029 17.6 0.1 2.0 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SH2 PF00017.19 KFP00718.1 - 6.3e-14 51.5 0.0 8e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 SH2 domain STAG PF08514.6 KFP00719.1 - 2e-47 159.7 0.2 9.9e-47 157.5 0.1 2.3 1 0 0 1 1 1 1 STAG domain Phage_DsbA PF11126.3 KFP00719.1 - 0.012 15.6 0.6 9.2 6.4 0.0 3.2 2 0 0 2 2 2 0 Transcriptional regulator DsbA AdoHcyase_NAD PF00670.16 KFP00719.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Tho2 PF11262.3 KFP00720.1 - 2.9e-97 325.3 2.2 2.9e-97 325.3 1.5 3.4 3 1 1 4 4 4 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KFP00720.1 - 2.5e-34 116.9 0.2 1.8e-32 110.9 0.1 3.0 3 0 0 3 3 3 1 Transcription- and export-related complex subunit Lig_chan PF00060.21 KFP00721.1 - 1.1e-59 200.3 0.0 2e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 KFP00721.1 - 9.9e-58 195.5 1.0 2.5e-57 194.2 0.9 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 KFP00721.1 - 2.1e-26 91.6 2.1 2.3e-26 91.5 0.2 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFP00721.1 - 4.9e-26 91.3 0.0 9e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PUA PF01472.15 KFP00723.1 - 7.3e-21 73.6 0.1 1.2e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 PUA domain Cullin PF00888.17 KFP00724.1 - 8.3e-178 592.5 20.2 1.2e-177 592.0 14.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFP00724.1 - 1.2e-27 95.5 1.0 1.2e-27 95.5 0.7 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain TrmB PF01978.14 KFP00724.1 - 0.06 13.0 0.1 9 6.0 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HbrB PF08539.6 KFP00724.1 - 0.11 12.3 7.5 0.018 14.8 1.0 2.7 3 0 0 3 3 3 0 HbrB-like Lamp PF01299.12 KFP00725.1 - 1.8e-100 336.0 11.1 5.6e-96 321.2 4.9 2.0 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) DUF368 PF04018.8 KFP00725.1 - 0.029 13.5 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF368) DUF4620 PF15399.1 KFP00725.1 - 0.038 14.1 0.7 0.074 13.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Na_K-ATPase PF00287.13 KFP00726.1 - 2.5e-89 298.8 0.3 3.1e-89 298.5 0.2 1.0 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain FAM70 PF14967.1 KFP00727.1 - 2.5e-162 539.6 6.1 2.8e-162 539.4 4.2 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.1 KFP00727.1 - 0.0015 18.6 11.3 0.89 9.6 7.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) DUF1097 PF06496.6 KFP00727.1 - 7.6 6.3 11.1 3 7.6 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) BTB PF00651.26 KFP00728.1 - 2.2e-20 72.6 0.1 3.9e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP00728.1 - 1.1e-06 28.5 9.4 0.00014 22.0 0.8 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP00728.1 - 5.5e-05 23.2 16.4 0.12 12.8 1.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP00728.1 - 0.033 14.5 15.9 0.34 11.3 0.8 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.2 KFP00728.1 - 0.07 12.9 4.7 0.16 11.7 3.2 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 KFP00728.1 - 0.083 13.0 7.1 0.19 11.9 4.9 1.6 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_6 PF13912.1 KFP00728.1 - 0.36 10.8 9.9 6.6 6.7 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger PyrI_C PF02748.10 KFP00728.1 - 0.62 9.5 4.9 0.24 10.8 0.7 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_4 PF07975.7 KFP00728.1 - 3 7.9 7.6 14 5.7 2.1 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain zf-BED PF02892.10 KFP00728.1 - 5.2 6.8 15.7 16 5.3 2.1 3.5 1 1 2 3 3 3 0 BED zinc finger SynMuv_product PF06047.6 KFP00729.1 - 3.4e-53 177.7 2.3 3.4e-53 177.7 1.6 3.0 2 1 0 3 3 3 1 Ras-induced vulval development antagonist Macoilin PF09726.4 KFP00729.1 - 1.3 7.2 25.5 1.7 6.8 17.7 1.2 1 0 0 1 1 1 0 Transmembrane protein CDC27 PF09507.5 KFP00729.1 - 1.3 8.1 49.3 0.04 13.1 29.8 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 LMBR1 PF04791.11 KFP00729.1 - 5.9 5.3 9.6 5.9 5.3 6.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AKAP28 PF14469.1 KFP00730.1 - 3.4e-49 165.4 2.3 3.8e-49 165.2 1.6 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor Smg4_UPF3 PF03467.10 KFP00731.1 - 2.6e-36 125.2 3.1 2.6e-36 125.2 2.1 3.2 3 1 1 4 4 4 1 Smg-4/UPF3 family Ribosomal_L39 PF00832.15 KFP00732.1 - 7e-24 83.0 10.1 8e-24 82.8 7.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Septin PF00735.13 KFP00733.1 - 4.9e-96 321.0 0.7 4.9e-96 321.0 0.5 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFP00733.1 - 0.00031 20.6 0.0 0.00073 19.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFP00733.1 - 0.00061 19.8 0.2 0.026 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFP00733.1 - 0.0062 16.6 2.6 0.0091 16.1 0.0 2.6 2 2 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KFP00733.1 - 0.013 14.9 1.3 1.1 8.6 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KFP00733.1 - 0.017 14.6 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KFP00733.1 - 0.026 15.0 2.3 0.036 14.5 0.1 2.5 2 1 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KFP00733.1 - 0.028 13.8 1.0 0.075 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain IMD PF08397.6 KFP00733.1 - 0.039 13.2 14.3 0.08 12.2 9.9 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF4478 PF14793.1 KFP00733.1 - 0.048 13.2 0.5 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4478) FtsK_SpoIIIE PF01580.13 KFP00733.1 - 0.06 12.8 2.3 0.91 8.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Fzo_mitofusin PF04799.8 KFP00733.1 - 0.1 11.9 7.4 0.26 10.6 5.1 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF87 PF01935.12 KFP00733.1 - 0.36 10.6 7.2 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 IncA PF04156.9 KFP00733.1 - 0.39 10.2 11.3 0.67 9.5 7.8 1.3 1 0 0 1 1 1 0 IncA protein ABC_tran PF00005.22 KFP00733.1 - 2.7 8.2 6.2 0.38 11.0 0.1 2.4 2 2 0 2 2 2 0 ABC transporter Atg14 PF10186.4 KFP00733.1 - 8.8 5.1 12.2 13 4.5 8.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_11 PF13086.1 KFP00733.1 - 9.5 5.7 10.5 12 5.4 6.6 1.5 1 1 0 1 1 1 0 AAA domain R3H PF01424.17 KFP00734.1 - 5.4e-15 54.8 0.3 1.6e-14 53.3 0.2 1.9 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KFP00734.1 - 1.4e-14 53.5 3.1 4.6e-14 51.9 2.2 2.0 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.20 KFP00734.1 - 6e-13 49.1 6.3 3.3e-05 24.3 0.1 4.3 4 0 0 4 4 4 3 Double-stranded RNA binding motif G-patch_2 PF12656.2 KFP00734.1 - 4.6e-05 23.1 0.8 0.00016 21.4 0.5 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site UQ_con PF00179.21 KFP00735.1 - 5.1e-40 136.1 0.1 5.7e-40 135.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP00735.1 - 3.8e-06 26.6 0.0 4.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFP00735.1 - 0.00084 19.2 0.2 0.0013 18.6 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KFP00735.1 - 0.0068 16.0 0.1 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Mito_carr PF00153.22 KFP00736.1 - 1e-57 191.8 1.0 1.3e-22 79.2 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 KFP00737.1 - 3.3e-52 174.1 0.2 4.2e-27 93.6 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Cyt-b5 PF00173.23 KFP00738.1 - 3.6e-14 52.3 0.0 4.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LON PF02190.11 KFP00740.1 - 1.1e-21 77.4 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KFP00740.1 - 4.7e-08 32.9 7.8 4.7e-08 32.9 5.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP00740.1 - 1.5e-07 31.1 8.7 1.5e-07 31.1 6.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFP00740.1 - 1.1e-06 28.2 7.7 1.1e-06 28.2 5.3 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP00740.1 - 1.2e-06 28.1 6.6 3.2e-06 26.7 4.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP00740.1 - 2.5e-06 27.0 7.8 6.4e-06 25.7 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP00740.1 - 7.3e-06 25.7 6.1 2.4e-05 24.1 4.2 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFP00740.1 - 0.00035 20.2 3.6 0.00035 20.2 2.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFP00740.1 - 0.0011 18.5 5.4 0.0011 18.5 3.7 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFP00740.1 - 0.0032 17.5 5.0 0.0087 16.1 3.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 KFP00740.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain Vps53_N PF04100.7 KFP00740.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal HCaRG PF07258.9 KFP00741.1 - 8.6e-33 113.3 0.0 9.6e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein PmbA_TldD PF01523.11 KFP00742.1 - 0.04 13.1 3.2 0.063 12.5 2.2 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Hex_IIIa PF02455.11 KFP00742.1 - 0.15 10.7 8.2 0.22 10.1 5.7 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) SOBP PF15279.1 KFP00742.1 - 0.39 11.0 9.8 0.59 10.4 6.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 KFP00742.1 - 0.51 9.6 20.1 0.48 9.7 13.1 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.12 KFP00742.1 - 1.1 8.9 8.5 1.7 8.3 5.9 1.3 1 0 0 1 1 1 0 DDHD domain TIR PF01582.15 KFP00743.1 - 1.8e-29 101.9 0.3 4.2e-29 100.8 0.1 1.7 2 0 0 2 2 2 1 TIR domain I-set PF07679.11 KFP00743.1 - 3.6e-21 74.8 0.1 5.1e-06 26.2 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP00743.1 - 1.1e-17 63.9 0.0 5.1e-06 26.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP00743.1 - 6e-13 49.1 0.0 0.00066 20.1 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP00743.1 - 7.4e-13 48.4 0.1 0.00016 21.6 0.1 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP00743.1 - 3.3e-12 46.2 0.0 0.0058 16.5 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin V-set domain TIR_2 PF13676.1 KFP00743.1 - 8.3e-05 22.6 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 TIR domain V-set_CD47 PF08204.6 KFP00743.1 - 0.00025 20.7 2.3 0.072 12.8 0.0 3.5 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.11 KFP00743.1 - 0.003 15.8 0.0 3 6.0 0.0 2.9 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E Pkinase PF00069.20 KFP00744.1 - 4.2e-57 193.2 0.0 8.8e-57 192.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.17 KFP00744.1 - 2.7e-53 181.1 0.0 4.8e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.12 KFP00744.1 - 1.1e-40 139.3 0.0 1.8e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP00744.1 - 5.6e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP00744.1 - 0.22 11.1 0.1 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family tRNA_anti-codon PF01336.20 KFP00745.1 - 0.0078 16.0 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4460 PF14687.1 KFP00745.1 - 0.065 12.9 0.1 0.77 9.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4460) zf-RING_2 PF13639.1 KFP00746.1 - 2.2e-13 49.7 7.5 3.5e-13 49.1 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFP00746.1 - 6.6e-11 41.7 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFP00746.1 - 9.2e-10 38.4 1.5 1.7e-09 37.6 1.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP00746.1 - 2.9e-07 30.0 7.9 4.6e-07 29.3 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP00746.1 - 5.2e-07 29.2 9.1 8.4e-07 28.6 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFP00746.1 - 6e-07 29.3 8.6 1e-06 28.6 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP00746.1 - 6.1e-06 25.8 6.8 9.2e-06 25.2 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFP00746.1 - 0.0058 16.4 3.4 0.011 15.5 2.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SieB PF14163.1 KFP00746.1 - 0.0088 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Superinfection exclusion protein B PHD PF00628.24 KFP00746.1 - 0.58 9.8 8.2 1 9.1 5.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 KFP00746.1 - 4.3 7.1 8.9 9.4 6.0 6.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 KFP00746.1 - 5.1 7.2 9.7 10 6.2 6.8 1.5 1 0 0 1 1 1 0 RING-variant domain RabGAP-TBC PF00566.13 KFP00747.1 - 1.1e-45 155.7 0.0 1.1e-45 155.7 0.0 2.5 4 0 0 4 4 4 1 Rab-GTPase-TBC domain GRAM PF02893.15 KFP00747.1 - 1.3e-29 101.4 0.7 4.4e-15 54.9 0.1 2.7 2 0 0 2 2 2 2 GRAM domain PAS PF00989.19 KFP00748.1 - 2.6e-10 40.1 0.0 3.8e-08 33.0 0.0 3.4 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.1 KFP00748.1 - 2.7e-10 40.1 1.4 7.7e-06 25.8 0.0 3.5 3 0 0 3 3 3 2 PAS domain HLH PF00010.21 KFP00748.1 - 6.3e-08 32.1 0.6 1.3e-07 31.1 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.6 KFP00748.1 - 7.7e-06 25.9 0.0 0.013 15.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.1 KFP00748.1 - 2.5e-05 24.6 0.0 0.00021 21.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain VMA21 PF09446.5 KFP00749.1 - 6.5e-21 74.0 7.1 7.3e-21 73.8 4.9 1.0 1 0 0 1 1 1 1 VMA21-like domain BCD PF15461.1 KFP00749.1 - 0.0043 16.5 0.2 0.0048 16.3 0.1 1.0 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase 7tm_7 PF08395.7 KFP00749.1 - 0.071 12.1 2.1 0.072 12.1 1.4 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Phage_holin_6 PF10746.4 KFP00749.1 - 0.071 12.8 0.6 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 Phage holin family 6 PAP2_3 PF14378.1 KFP00749.1 - 0.35 10.3 2.9 0.72 9.3 2.0 1.5 1 1 0 1 1 1 0 PAP2 superfamily DUF4448 PF14610.1 KFP00749.1 - 0.74 9.2 2.5 1.1 8.6 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) 7tm_1 PF00001.16 KFP00750.1 - 3e-54 183.8 22.9 3e-54 183.8 15.9 1.4 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00750.1 - 7.1e-08 31.9 26.4 9.9e-08 31.4 18.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Serpentine_r_xa PF03383.10 KFP00750.1 - 0.085 12.6 17.1 0.021 14.5 1.6 2.7 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srx PF10328.4 KFP00750.1 - 0.16 11.0 32.7 0.81 8.7 22.7 2.1 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_1 PF00001.16 KFP00751.1 - 2.8e-40 138.1 20.5 3.8e-40 137.6 14.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NdhL PF10716.4 KFP00751.1 - 2.3 8.0 6.5 1.9 8.3 1.6 2.8 2 1 1 3 3 3 0 NADH dehydrogenase transmembrane subunit 7tm_1 PF00001.16 KFP00752.1 - 4.9e-46 156.9 15.2 7.7e-46 156.3 10.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFP00752.1 - 0.002 17.3 14.0 0.038 13.1 0.3 2.4 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_1 PF00001.16 KFP00753.1 - 8.7e-47 159.4 17.4 1e-46 159.2 12.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFP00753.1 - 4.8e-05 22.6 0.5 4.8e-05 22.6 0.4 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF2975 PF11188.3 KFP00753.1 - 0.0031 17.2 1.9 0.0031 17.2 1.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2975) BRICHOS PF04089.9 KFP00754.1 - 2.7e-28 97.6 0.0 5.3e-28 96.7 0.0 1.5 2 0 0 2 2 2 1 BRICHOS domain T-box PF00907.17 KFP00755.1 - 1.3e-81 272.4 0.2 1.5e-81 272.3 0.1 1.0 1 0 0 1 1 1 1 T-box Snf7 PF03357.16 KFP00756.1 - 4.5e-27 94.5 18.1 5e-27 94.3 12.5 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 KFP00756.1 - 1e-05 25.0 6.3 1.4e-05 24.5 4.4 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Mu-like_Pro PF10123.4 KFP00756.1 - 0.0041 16.6 9.3 0.0054 16.2 6.4 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein GrpE PF01025.14 KFP00756.1 - 0.013 15.0 7.9 0.021 14.3 5.5 1.3 1 0 0 1 1 1 0 GrpE MAP65_ASE1 PF03999.7 KFP00756.1 - 0.014 14.0 4.5 0.019 13.6 3.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HAUS5 PF14817.1 KFP00756.1 - 0.096 11.2 7.3 0.12 10.9 5.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF948 PF06103.6 KFP00756.1 - 0.32 10.8 7.9 0.21 11.4 3.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_D PF05873.7 KFP00756.1 - 0.35 10.5 3.6 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF939_C PF11728.3 KFP00756.1 - 0.52 10.0 10.7 1.7 8.4 2.6 2.2 1 1 1 2 2 2 0 DUF939 C-terminal domain Fib_alpha PF08702.5 KFP00756.1 - 1.6 8.8 8.6 1 9.4 1.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HSCB_C PF07743.8 KFP00756.1 - 3.9 8.0 8.1 22 5.5 1.6 2.6 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain FlxA PF14282.1 KFP00756.1 - 9.3 6.2 12.8 1.2 9.0 2.3 2.3 1 1 1 2 2 2 0 FlxA-like protein DUF1693 PF07984.7 KFP00757.1 - 2e-169 562.8 3.0 2.2e-169 562.6 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) HMG14_17 PF01101.13 KFP00758.1 - 7.9e-22 77.7 40.4 2.8e-21 75.9 28.0 1.7 1 1 0 1 1 1 1 HMG14 and HMG17 Pap_E4 PF02711.9 KFP00758.1 - 4.6 8.1 11.3 11 6.9 7.8 1.7 1 1 0 1 1 1 0 E4 protein Pox_Ag35 PF03286.9 KFP00758.1 - 9.1 5.7 21.1 11 5.5 14.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SH3BGR PF04908.10 KFP00759.1 - 1.8e-36 124.0 0.1 2.1e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KFP00759.1 - 0.00054 19.8 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF4569 PF15133.1 KFP00760.1 - 9.6e-92 307.6 0.2 1.1e-91 307.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) Na_H_Exchanger PF00999.16 KFP00761.1 - 3e-79 266.2 36.3 3.6e-79 266.0 25.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Claudin_2 PF13903.1 KFP00762.1 - 4.4e-24 85.0 3.3 6.2e-24 84.6 2.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP00762.1 - 0.0049 16.5 7.6 0.091 12.4 3.3 2.6 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Pkinase PF00069.20 KFP00763.1 - 1.7e-144 479.6 0.0 1.1e-71 241.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00763.1 - 7.4e-76 254.6 0.0 7.9e-40 136.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFP00763.1 - 2.3e-14 53.0 0.0 1.3e-07 30.8 0.0 3.7 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 KFP00763.1 - 3.7e-10 39.2 0.0 1.6e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP00763.1 - 1.9e-06 27.7 0.3 0.18 11.5 0.0 3.5 2 2 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_C PF00433.19 KFP00763.1 - 3.4e-06 27.4 1.0 7.6e-06 26.3 0.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain YrbL-PhoP_reg PF10707.4 KFP00763.1 - 3.9e-06 26.3 0.0 0.0084 15.4 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFP00763.1 - 0.0055 16.0 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 KFP00763.1 - 0.046 13.2 0.1 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 KFP00763.1 - 0.12 11.1 0.1 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Homeobox PF00046.24 KFP00764.1 - 3.6e-11 42.5 2.0 6.3e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Homeobox domain DUF1170 PF06663.8 KFP00765.1 - 1.3e-60 204.6 1.8 2.4e-60 203.7 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.4 KFP00765.1 - 7.2e-41 138.1 1.6 9.6e-41 137.7 0.1 2.1 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.25 KFP00765.1 - 1.8e-14 53.6 0.3 4.9e-14 52.2 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KFP00765.1 - 3.2e-13 49.7 2.4 9.3e-13 48.2 1.7 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KFP00765.1 - 4.4e-10 39.2 0.9 1.3e-09 37.7 0.3 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PDZ PF00595.19 KFP00765.1 - 6.3e-10 39.1 0.0 1.6e-08 34.6 0.0 2.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP00765.1 - 0.0066 16.3 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.1 KFP00765.1 - 0.012 15.8 6.3 0.037 14.2 4.4 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Peptidase_C98 PF15499.1 KFP00765.1 - 0.046 12.9 0.7 0.12 11.6 0.5 1.6 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ApoO PF09769.4 KFP00766.1 - 5.1e-41 140.0 1.9 1.1e-40 138.9 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein O Zfx_Zfy_act PF04704.8 KFP00767.1 - 2e-137 457.5 17.3 2e-137 457.5 12.0 1.5 2 0 0 2 2 2 1 Zfx / Zfy transcription activation region zf-H2C2_2 PF13465.1 KFP00767.1 - 5.4e-40 133.7 118.8 3.3e-06 27.1 3.4 13.0 13 0 0 13 13 13 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFP00767.1 - 1.5e-37 125.6 116.8 4.8e-06 26.5 1.9 12.3 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP00767.1 - 2.9e-29 99.2 102.4 0.00021 21.3 1.2 12.4 12 0 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP00767.1 - 4.8e-20 70.5 100.5 0.00019 21.4 3.2 12.1 12 0 0 12 12 12 8 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFP00767.1 - 3.7e-14 52.3 76.3 8.2e-05 22.6 0.1 11.6 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP00767.1 - 0.12 12.5 0.1 0.12 12.5 0.1 10.8 11 0 0 11 11 11 0 Zinc-finger of C2H2 type Cast PF10174.4 KFP00768.1 - 0.0054 14.8 7.1 0.0054 14.8 4.9 2.1 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.6 KFP00768.1 - 0.59 8.7 24.3 0.55 8.8 4.6 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.6 KFP00768.1 - 0.75 9.5 30.2 3.4 7.4 8.7 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Sec2p PF06428.6 KFP00768.1 - 0.78 9.6 15.4 0.092 12.5 0.8 3.8 2 2 1 3 3 3 0 GDP/GTP exchange factor Sec2p Reo_sigmaC PF04582.7 KFP00768.1 - 0.84 8.7 5.3 7.7 5.5 0.6 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 KFP00768.1 - 5.9 6.7 27.9 2.5 8.0 5.7 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GDI PF00996.13 KFP00769.1 - 6.5e-87 291.6 0.2 9.9e-69 231.7 0.1 2.3 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_oxidored PF12831.2 KFP00769.1 - 7.3e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFP00769.1 - 0.00011 21.2 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFP00769.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Macoilin PF09726.4 KFP00770.1 - 0.00056 18.3 19.9 0.0011 17.3 13.8 1.5 1 1 0 1 1 1 1 Transmembrane protein Kelch_1 PF01344.20 KFP00771.1 - 7.2e-76 249.5 13.2 1.4e-14 53.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFP00771.1 - 1.7e-51 170.3 7.7 1.1e-09 38.0 0.0 6.3 2 2 4 6 6 6 6 Kelch motif BACK PF07707.10 KFP00771.1 - 5.2e-32 109.7 2.1 6.6e-32 109.4 0.0 2.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFP00771.1 - 9.7e-32 108.5 11.1 5.9e-06 25.9 0.0 6.4 4 2 2 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFP00771.1 - 2.2e-31 108.1 2.0 3e-31 107.6 0.7 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFP00771.1 - 1.6e-26 91.8 13.8 0.00045 20.3 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP00771.1 - 4e-25 86.5 7.7 3.3e-06 26.6 0.0 7.2 7 0 0 7 7 7 5 Kelch motif Kelch_5 PF13854.1 KFP00771.1 - 1.1e-06 28.4 9.1 0.11 12.4 0.0 6.3 7 0 0 7 7 7 2 Kelch motif PQQ_3 PF13570.1 KFP00771.1 - 0.65 10.3 6.0 48 4.4 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain Cadherin PF00028.12 KFP00772.1 - 3.2e-113 370.2 5.7 1.9e-22 79.3 0.1 7.5 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 KFP00772.1 - 3.2e-95 317.9 2.1 6.2e-95 317.0 1.5 1.5 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 KFP00772.1 - 2.7e-17 62.0 0.3 6.2e-09 35.3 0.0 5.0 5 0 0 5 5 5 3 Cadherin-like He_PIG PF05345.7 KFP00772.1 - 0.028 14.4 4.3 3.7 7.6 0.0 5.0 4 1 0 4 4 4 0 Putative Ig domain Y_Y_Y PF07495.8 KFP00772.1 - 0.076 12.7 0.0 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 Y_Y_Y domain BRICHOS PF04089.9 KFP00775.1 - 8.8e-20 70.3 0.0 1.5e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 BRICHOS domain Tetraspannin PF00335.15 KFP00776.1 - 8.3e-29 100.4 6.7 1e-28 100.1 4.6 1.1 1 0 0 1 1 1 1 Tetraspanin family FixQ PF05545.6 KFP00776.1 - 0.018 14.6 0.3 0.041 13.5 0.2 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF4190 PF13828.1 KFP00776.1 - 0.053 13.0 3.1 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Vsr PF03852.10 KFP00776.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr FeoB_C PF07664.7 KFP00776.1 - 0.08 12.3 0.2 0.08 12.3 0.1 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus UPF0016 PF01169.14 KFP00776.1 - 0.15 12.1 1.8 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 ABC2_membrane_4 PF12730.2 KFP00776.1 - 0.38 9.8 3.8 6.1 5.9 0.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF307 PF03733.8 KFP00776.1 - 1.2 9.5 5.9 0.67 10.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF307) P12 PF12669.2 KFP00776.1 - 3.1 8.0 7.1 20 5.4 0.3 3.1 3 0 0 3 3 3 0 Virus attachment protein p12 family DUF4174 PF13778.1 KFP00777.1 - 3e-29 101.4 0.0 4.1e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Sushi PF00084.15 KFP00777.1 - 8.6e-27 93.2 23.6 3e-11 43.5 4.2 3.7 3 0 0 3 3 3 3 Sushi domain (SCR repeat) HYR PF02494.11 KFP00777.1 - 1.3e-24 86.0 0.0 2e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 HYR domain cEGF PF12662.2 KFP00777.1 - 0.43 10.2 16.8 0.28 10.8 1.3 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like Met_10 PF02475.11 KFP00778.1 - 2e-29 102.6 0.0 2.5e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KFP00778.1 - 3.3e-07 30.3 0.1 6.7e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP00778.1 - 6.4e-05 22.3 0.0 9.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KFP00778.1 - 0.00088 19.8 0.1 0.0022 18.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFP00778.1 - 0.049 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 KFP00778.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HAD PF12710.2 KFP00779.1 - 2.2e-18 67.1 0.2 7e-18 65.4 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFP00779.1 - 2.5e-16 59.4 0.0 2.5e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFP00779.1 - 2.3e-12 46.7 0.0 8e-12 44.9 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KFP00779.1 - 3.9e-11 43.7 0.6 5.8e-07 30.1 0.3 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFP00779.1 - 0.0082 15.7 0.0 0.48 9.9 0.0 2.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RhoGEF PF00621.15 KFP00780.1 - 7.1e-22 78.1 10.1 1.7e-21 76.8 0.1 3.4 3 1 0 3 3 3 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 KFP00780.1 - 1.3e-16 60.7 0.0 3.8e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.24 KFP00780.1 - 6.6e-05 23.0 0.1 0.00015 21.9 0.1 1.6 1 0 0 1 1 1 1 PH domain Spectrin PF00435.16 KFP00780.1 - 0.0058 16.8 1.4 0.0058 16.8 0.9 4.1 5 1 0 5 5 5 1 Spectrin repeat DUF948 PF06103.6 KFP00780.1 - 0.093 12.5 0.6 0.92 9.4 0.1 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Crp PF00325.15 KFP00780.1 - 0.1 12.0 0.1 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Trypsin PF00089.21 KFP00781.1 - 4.3e-64 216.1 0.8 5.7e-64 215.6 0.6 1.2 1 0 0 1 1 1 1 Trypsin Gla PF00594.15 KFP00781.1 - 5.4e-18 64.4 6.1 8.8e-18 63.7 4.2 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain FXa_inhibition PF14670.1 KFP00781.1 - 7.5e-14 51.5 22.6 6.4e-12 45.3 5.2 2.8 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFP00781.1 - 2.7e-08 33.6 18.3 1.2e-07 31.4 4.1 2.8 2 0 0 2 2 2 2 EGF-like domain cEGF PF12662.2 KFP00781.1 - 4.4e-07 29.4 10.3 0.00032 20.2 0.8 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like DUF1986 PF09342.6 KFP00781.1 - 4.7e-06 26.0 0.0 7.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFP00781.1 - 3.1e-05 23.9 0.0 7.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain EGF_CA PF07645.10 KFP00781.1 - 0.095 12.7 19.3 0.51 10.3 8.4 3.1 2 1 0 2 2 2 0 Calcium-binding EGF domain Haemagg_act PF05860.8 KFP00781.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 haemagglutination activity domain DUF2470 PF10615.4 KFP00781.1 - 0.13 12.5 0.6 0.22 11.7 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2470) EGF_3 PF12947.2 KFP00781.1 - 0.14 12.1 22.8 0.78 9.7 5.0 2.8 2 0 0 2 2 2 0 EGF domain hEGF PF12661.2 KFP00781.1 - 2.6 8.3 16.3 0.13 12.3 3.7 3.3 3 0 0 3 3 2 0 Human growth factor-like EGF FGF PF00167.13 KFP00782.1 - 9.3e-45 151.3 0.3 1.2e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFP00782.1 - 0.00036 20.6 0.1 0.0036 17.3 0.0 2.1 1 1 1 2 2 2 1 Fascin domain zf-C2H2 PF00096.21 KFP00784.1 - 1.6e-21 75.2 31.5 3.4e-06 27.0 2.0 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP00784.1 - 7.7e-18 63.8 45.9 4.7e-08 32.9 0.2 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP00784.1 - 2.9e-16 58.5 25.4 0.0002 21.4 0.6 5.7 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP00784.1 - 4.4e-09 36.2 17.7 0.00014 21.9 0.1 4.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP00784.1 - 3.4e-05 23.8 11.4 0.00029 20.9 0.7 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP00784.1 - 0.0014 18.4 9.7 0.0028 17.5 0.2 4.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP00784.1 - 4.2 7.7 14.7 0.37 11.1 1.3 4.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain EMP70 PF02990.11 KFP00785.1 - 2.7e-215 715.7 8.2 3.2e-215 715.5 5.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 RRM_1 PF00076.17 KFP00786.1 - 1.3e-23 82.4 0.1 1.9e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM1CTR PF08081.6 KFP00786.1 - 1e-22 79.5 18.9 1e-22 79.5 13.1 10.0 5 3 5 10 10 10 1 RBM1CTR (NUC064) family RRM_6 PF14259.1 KFP00786.1 - 7.8e-17 61.0 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00786.1 - 1.7e-11 43.7 0.0 2.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGEF PF00621.15 KFP00787.1 - 2.5e-33 115.4 1.2 2.5e-33 115.4 0.9 2.9 2 1 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KFP00787.1 - 4e-17 61.5 0.2 9e-17 60.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP00787.1 - 1.6e-16 59.5 0.5 3.1e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP00787.1 - 7.2e-15 54.1 0.3 1.3e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KFP00787.1 - 3.8e-12 46.3 0.0 1.5e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 PH domain CH PF00307.26 KFP00787.1 - 2e-11 43.8 0.0 6.2e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP00787.1 - 1.5e-05 24.5 0.0 5.6e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain FlgN PF05130.7 KFP00787.1 - 0.011 15.9 10.2 2.6 8.3 0.6 3.6 3 0 0 3 3 3 0 FlgN protein Nsp1_C PF05064.8 KFP00787.1 - 0.041 13.5 10.4 0.033 13.8 1.2 3.9 4 1 0 4 4 4 0 Nsp1-like C-terminal region MutS_III PF05192.13 KFP00787.1 - 0.065 13.0 5.2 1.2 8.8 0.2 3.2 2 1 0 2 2 2 0 MutS domain III DUF745 PF05335.8 KFP00787.1 - 4 6.9 7.2 1.7 8.1 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF972 PF06156.8 KFP00787.1 - 4 7.8 14.0 2.2 8.6 2.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KFP00787.1 - 5.6 7.3 17.5 0.025 14.8 2.8 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF904) OmpH PF03938.9 KFP00787.1 - 7.9 6.3 10.6 2.5 8.0 0.3 3.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) TNF PF00229.13 KFP00788.1 - 5.4e-30 103.5 0.6 1.1e-29 102.6 0.1 1.7 2 0 0 2 2 2 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 KFP00788.1 - 0.0014 18.6 0.3 0.0058 16.6 0.2 2.1 1 1 0 1 1 1 1 C1q domain Vg_Tdu PF07545.9 KFP00790.1 - 2e-20 71.8 0.2 3.7e-20 71.0 0.2 1.4 1 0 0 1 1 1 1 Vestigial/Tondu family RRM_1 PF00076.17 KFP00791.1 - 3.7e-17 61.7 0.1 6.8e-07 28.8 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00791.1 - 1.4e-12 47.2 0.0 2.2e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00791.1 - 1.4e-09 37.7 0.1 0.00033 20.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAM104 PF15434.1 KFP00791.1 - 4.3 7.5 8.0 0.29 11.3 1.4 2.1 2 0 0 2 2 2 0 Family 104 7tm_1 PF00001.16 KFP00792.1 - 6.4e-59 199.1 14.1 8.7e-59 198.7 9.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00792.1 - 3.3e-11 42.8 13.8 5.4e-11 42.1 9.6 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP00792.1 - 2.6e-09 36.6 14.4 3.4e-09 36.2 10.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFP00792.1 - 0.00035 19.7 14.3 0.00052 19.2 9.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx TAS2R PF05296.8 KFP00792.1 - 0.0004 19.3 4.4 0.0004 19.3 3.1 2.0 2 0 0 2 2 2 1 Mammalian taste receptor protein (TAS2R) PsbI PF02532.9 KFP00792.1 - 0.15 11.6 1.4 0.79 9.4 0.0 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF912 PF06024.7 KFP00792.1 - 5.4 7.1 6.9 3.7 7.6 1.7 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MAP7 PF05672.6 KFP00793.1 - 2.8e-43 147.2 70.5 2.8e-43 147.2 48.9 3.1 2 1 0 2 2 2 1 MAP7 (E-MAP-115) family LIM PF00412.17 KFP00794.1 - 9.2e-47 156.9 73.7 1.9e-12 47.0 7.2 5.1 5 0 0 5 5 5 5 LIM domain zf-RING_6 PF14835.1 KFP00794.1 - 0.0034 17.1 1.7 0.0034 17.1 1.2 5.3 5 1 0 5 5 5 2 zf-RING of BARD1-type protein Ureidogly_hydro PF04115.7 KFP00794.1 - 0.011 15.0 0.0 1.5 8.1 0.0 2.9 1 1 1 2 2 2 0 Ureidoglycolate hydrolase Sgf11 PF08209.6 KFP00794.1 - 0.063 12.6 0.4 0.063 12.6 0.3 9.4 11 2 1 12 12 12 0 Sgf11 (transcriptional regulation protein) TNFR_c6 PF00020.13 KFP00794.1 - 0.14 12.2 0.4 0.14 12.2 0.3 9.1 9 3 1 10 10 10 0 TNFR/NGFR cysteine-rich region DUF2685 PF10886.3 KFP00794.1 - 7.8 6.5 14.3 17 5.4 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2685) Na_H_Exchanger PF00999.16 KFP00795.1 - 2.2e-72 243.6 37.4 4.3e-72 242.7 25.9 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family MMgT PF10270.4 KFP00796.1 - 3.7e-15 56.2 0.0 5.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Motile_Sperm PF00635.21 KFP00797.1 - 1.5e-16 59.9 0.3 2.4e-16 59.3 0.1 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain FAM101 PF15068.1 KFP00798.1 - 0.13 11.6 3.5 0.13 11.6 0.7 2.1 2 0 0 2 2 2 0 FAM101 family DUF1582 PF07621.6 KFP00798.1 - 0.45 10.5 5.9 9.4 6.4 3.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1582) DUF1582 PF07621.6 KFP00799.1 - 1.3 9.1 6.8 10 6.2 2.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1582) Pribosyltran PF00156.22 KFP00800.1 - 1.1e-06 28.3 0.0 0.00049 19.8 0.0 2.1 2 0 0 2 2 2 2 Phosphoribosyl transferase domain zf-HC5HC2H PF13771.1 KFP00801.1 - 5.2e-35 119.4 31.3 1.2e-18 66.9 6.3 3.5 4 0 0 4 4 4 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFP00801.1 - 1.3e-12 47.6 27.9 2.2e-06 27.6 8.7 2.8 2 1 1 3 3 3 2 PHD-zinc-finger like domain zf-Apc11 PF12861.2 KFP00801.1 - 0.26 11.1 14.4 3.1 7.7 0.3 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2 PF00096.21 KFP00802.1 - 4.6e-12 45.5 8.9 2.5e-06 27.4 1.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP00802.1 - 5.2e-09 35.9 12.7 5e-07 29.6 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP00802.1 - 2.1e-08 33.9 6.0 0.0012 19.0 0.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP00802.1 - 5.6e-06 26.0 7.1 0.00013 21.7 0.8 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger XPA_N PF01286.13 KFP00802.1 - 0.00022 20.8 4.1 0.0034 17.0 0.2 2.2 2 0 0 2 2 2 1 XPA protein N-terminal zf-C2H2_jaz PF12171.3 KFP00802.1 - 0.0016 18.5 5.3 0.021 14.9 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 KFP00802.1 - 0.0034 17.1 4.6 0.043 13.6 3.2 2.1 1 1 0 1 1 1 1 Transposase zinc-ribbon domain LIM PF00412.17 KFP00802.1 - 0.0064 16.5 0.6 0.0086 16.1 0.4 1.3 1 1 0 1 1 1 1 LIM domain zf-met PF12874.2 KFP00802.1 - 0.012 15.7 6.7 0.54 10.5 1.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KFP00802.1 - 0.014 15.3 3.9 0.61 10.0 0.3 2.2 1 1 1 2 2 2 0 Zinc ribbon domain PHD PF00628.24 KFP00802.1 - 0.053 13.2 2.4 0.065 12.9 1.6 1.1 1 0 0 1 1 1 0 PHD-finger zf-Di19 PF05605.7 KFP00802.1 - 0.055 13.5 2.4 0.65 10.1 0.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_2 PF13240.1 KFP00802.1 - 0.066 12.7 6.4 0.51 9.8 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.16 KFP00802.1 - 0.11 12.3 2.5 3.4 7.6 0.0 2.1 1 1 1 2 2 2 0 IBR domain zinc_ribbon_5 PF13719.1 KFP00802.1 - 0.12 11.9 3.0 1.1 8.8 2.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFP00802.1 - 0.16 11.7 2.8 1.5 8.5 1.9 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_3 PF14369.1 KFP00802.1 - 0.17 11.9 8.2 0.91 9.5 0.2 2.3 2 0 0 2 2 2 0 zinc-finger UPF0547 PF10571.4 KFP00802.1 - 0.18 11.5 4.6 5.6 6.7 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ISL3 PF14690.1 KFP00802.1 - 0.19 11.7 5.8 3.4 7.7 1.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.1 KFP00802.1 - 0.27 10.4 7.4 1.2 8.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KFP00802.1 - 0.29 10.9 2.8 0.52 10.1 2.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-trcl PF13451.1 KFP00802.1 - 0.4 10.3 3.6 1.8 8.2 0.1 2.4 2 1 0 2 2 2 0 Probable zinc-binding domain YhfH PF14149.1 KFP00802.1 - 0.42 10.4 4.3 1.9 8.3 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein zf-Mss51 PF13824.1 KFP00802.1 - 0.45 10.4 6.3 0.16 11.8 0.4 2.2 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-BED PF02892.10 KFP00802.1 - 0.47 10.2 3.6 0.67 9.7 1.1 2.0 1 1 1 2 2 2 0 BED zinc finger FYVE PF01363.16 KFP00802.1 - 0.62 10.0 3.7 4.5 7.2 1.0 2.0 1 1 1 2 2 2 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.6 KFP00802.1 - 1.3 8.6 4.2 5.7 6.6 2.9 1.9 1 1 0 1 1 1 0 Putative transposase DNA-binding domain TFIIS_C PF01096.13 KFP00802.1 - 1.5 8.5 3.9 27 4.4 2.7 2.3 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Nudix_N_2 PF14803.1 KFP00802.1 - 1.7 8.3 4.0 19 5.0 0.2 2.5 2 1 0 2 2 2 0 Nudix N-terminal zf-AN1 PF01428.11 KFP00802.1 - 2.3 8.1 6.3 11 6.0 2.9 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-CCHC_5 PF14787.1 KFP00802.1 - 2.9 7.4 9.7 8.4 5.9 1.2 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-LYAR PF08790.6 KFP00802.1 - 4 7.2 6.3 7.1 6.4 0.4 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-dskA_traR PF01258.12 KFP00802.1 - 4.1 7.2 5.2 6.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Prok-RING_1 PF14446.1 KFP00802.1 - 4.8 6.9 6.7 37 4.1 2.7 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 TSP_1 PF00090.14 KFP00802.1 - 6.3 7.0 6.0 2.9 8.0 0.3 2.1 1 1 1 2 2 2 0 Thrombospondin type 1 domain ADK_lid PF05191.9 KFP00802.1 - 6.9 6.4 6.1 13 5.4 1.8 2.5 2 1 1 3 3 3 0 Adenylate kinase, active site lid zf-C2H2 PF00096.21 KFP00803.1 - 4.3e-10 39.3 7.8 4.8e-05 23.4 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP00803.1 - 4.3e-07 29.8 7.3 0.0034 17.5 0.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFP00803.1 - 2.6e-06 27.2 1.5 0.013 15.4 0.1 2.1 2 0 0 2 2 2 2 Zinc ribbon domain XPA_N PF01286.13 KFP00803.1 - 1.8e-05 24.3 0.4 0.091 12.4 0.0 2.1 2 0 0 2 2 2 2 XPA protein N-terminal zf-H2C2_2 PF13465.1 KFP00803.1 - 4.1e-05 23.6 11.4 0.0021 18.2 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 KFP00803.1 - 0.00015 21.4 5.5 0.089 12.5 1.0 2.1 1 1 1 2 2 2 2 BED zinc finger zf-LYAR PF08790.6 KFP00803.1 - 0.0005 19.7 0.9 0.59 9.8 0.1 2.2 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.3 KFP00803.1 - 0.0006 19.8 3.0 0.4 10.8 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP00803.1 - 0.00071 19.3 3.9 0.28 11.1 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger HNH PF01844.18 KFP00803.1 - 0.0024 17.7 2.6 0.99 9.3 0.1 2.1 2 0 0 2 2 2 2 HNH endonuclease GCC2_GCC3 PF07699.8 KFP00803.1 - 0.0098 15.4 1.2 0.79 9.3 0.1 2.1 2 0 0 2 2 2 1 GCC2 and GCC3 FYVE PF01363.16 KFP00803.1 - 0.01 15.7 5.3 0.25 11.2 0.3 2.0 1 1 1 2 2 2 0 FYVE zinc finger TFIIS_C PF01096.13 KFP00803.1 - 0.01 15.4 3.2 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DNA_RNApol_7kD PF03604.8 KFP00803.1 - 0.011 15.2 0.2 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.1 KFP00803.1 - 0.014 15.1 0.7 2 8.2 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 YhfH PF14149.1 KFP00803.1 - 0.019 14.7 2.4 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein zinc_ribbon_2 PF13240.1 KFP00803.1 - 0.031 13.7 4.9 0.97 9.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFP00803.1 - 0.033 13.3 1.2 0.4 9.9 0.9 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.1 KFP00803.1 - 0.066 12.8 2.0 6 6.5 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain ROS_MUCR PF05443.6 KFP00803.1 - 0.076 12.7 0.9 8 6.2 0.1 2.0 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C2H2_2 PF12756.2 KFP00803.1 - 0.08 13.0 3.6 3.2 7.8 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SprT-like PF10263.4 KFP00803.1 - 0.081 12.5 1.4 0.13 11.8 0.6 1.6 1 1 1 2 2 2 0 SprT-like family UPF0547 PF10571.4 KFP00803.1 - 0.086 12.5 0.8 7.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PhnA_Zn_Ribbon PF08274.7 KFP00803.1 - 0.091 12.5 1.5 2.2 8.1 0.0 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DZR PF12773.2 KFP00803.1 - 0.13 12.0 1.2 0.21 11.4 0.9 1.4 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 KFP00803.1 - 0.15 11.5 6.3 1.1 8.8 0.6 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF2256 PF10013.4 KFP00803.1 - 0.17 11.6 0.6 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) TF_Zn_Ribbon PF08271.7 KFP00803.1 - 0.17 11.2 1.2 7.5 5.9 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Ribosomal_L44 PF00935.14 KFP00803.1 - 0.18 11.7 3.6 4.8 7.2 0.2 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 HPIH PF13323.1 KFP00803.1 - 0.23 11.1 0.8 15 5.2 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain with HPIH motif zf-met PF12874.2 KFP00803.1 - 0.25 11.5 1.5 13 6.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpXC PF14353.1 KFP00803.1 - 0.32 10.9 1.5 14 5.6 0.1 2.0 1 1 1 2 2 2 0 CpXC protein Ogr_Delta PF04606.7 KFP00803.1 - 0.33 10.6 3.0 5.9 6.6 0.3 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger LIM PF00412.17 KFP00803.1 - 0.42 10.7 2.4 7.8 6.6 1.6 2.1 1 1 0 1 1 1 0 LIM domain C1_1 PF00130.17 KFP00803.1 - 0.91 9.3 3.6 3.2 7.5 0.6 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC5 PF06221.8 KFP00803.1 - 1.5 8.6 8.7 0.54 10.0 0.3 2.6 1 1 2 3 3 3 0 Putative zinc finger motif, C2HC5-type TMF_DNA_bd PF12329.3 KFP00805.1 - 0.036 13.8 1.0 0.07 12.9 0.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding C1q PF00386.16 KFP00808.1 - 6.8e-24 84.2 0.2 3.9e-23 81.8 0.0 2.5 2 0 0 2 2 2 1 C1q domain EMI PF07546.8 KFP00808.1 - 8.4e-15 54.9 3.3 8.4e-15 54.9 2.3 2.1 2 0 0 2 2 2 1 EMI domain EGF PF00008.22 KFP00808.1 - 3.2e-05 23.7 6.7 3.2e-05 23.7 4.6 1.8 2 0 0 2 2 2 1 EGF-like domain MitMem_reg PF13012.1 KFP00808.1 - 0.0085 16.1 2.9 0.0085 16.1 2.0 5.7 4 1 2 6 6 6 2 Maintenance of mitochondrial structure and function YvrJ PF12841.2 KFP00808.1 - 0.7 9.2 3.5 13 5.1 0.2 4.2 3 0 0 3 3 3 0 YvrJ protein family Synuclein PF01387.12 KFP00810.1 - 2.9e-60 201.8 18.7 3.3e-60 201.7 12.9 1.0 1 0 0 1 1 1 1 Synuclein RhoGAP PF00620.22 KFP00811.1 - 4.2e-45 153.0 0.4 2.5e-44 150.5 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain RCC1 PF00415.13 KFP00812.1 - 7.6e-85 278.9 30.0 1.1e-14 54.3 0.1 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 KFP00812.1 - 4.2e-84 282.3 0.5 6.5e-84 281.7 0.3 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.1 KFP00812.1 - 2.5e-46 154.3 45.2 2.1e-09 36.7 0.1 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 KFP00813.1 - 9.2e-28 97.3 0.0 1e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Trm112p PF03966.11 KFP00814.1 - 7.7e-05 22.9 0.5 0.00026 21.3 0.0 2.0 2 1 0 2 2 2 1 Trm112p-like protein RNA_pol_Rpb2_6 PF00562.23 KFP00815.1 - 7.3e-127 423.2 0.3 1.3e-126 422.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.9 KFP00815.1 - 2.5e-56 190.1 0.0 7.4e-56 188.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.10 KFP00815.1 - 3.1e-56 189.5 0.0 5.3e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KFP00815.1 - 4.2e-31 107.0 0.1 1.3e-30 105.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KFP00815.1 - 9.2e-29 99.0 0.9 1.9e-28 98.0 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KFP00815.1 - 4.9e-22 77.4 0.0 1.1e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KFP00815.1 - 3.7e-20 71.6 0.7 7.4e-20 70.6 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 KFP00815.1 - 0.045 13.5 0.5 0.13 12.1 0.4 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Amidoligase_2 PF12224.3 KFP00815.1 - 0.056 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme zf-H2C2_2 PF13465.1 KFP00816.1 - 2.1e-28 97.1 66.3 7.3e-09 35.4 0.8 11.2 11 1 0 11 11 11 6 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFP00816.1 - 2.4e-19 68.3 76.4 9.9e-05 22.3 1.3 9.4 9 0 0 9 9 9 7 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFP00816.1 - 1e-12 47.5 79.2 0.0015 18.7 3.1 9.4 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP00816.1 - 1.8e-08 34.1 78.3 0.021 15.1 2.0 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger DUF1183 PF06682.7 KFP00817.1 - 5.8e-85 285.6 3.7 6.6e-85 285.5 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Cytochrom_B561 PF03188.11 KFP00817.1 - 0.0024 17.6 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Vps55 PF04133.9 KFP00818.1 - 1.2e-29 102.4 2.4 1.4e-29 102.3 1.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 SRP72 PF08492.7 KFP00819.1 - 2e-20 72.8 7.0 2e-20 72.8 4.9 2.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 KFP00819.1 - 2.3e-16 59.8 16.9 0.0038 17.5 0.1 7.3 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KFP00819.1 - 1.5e-15 55.7 15.3 0.0045 16.7 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFP00819.1 - 8.9e-15 53.8 7.0 0.18 12.5 0.0 8.0 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFP00819.1 - 3.3e-11 42.9 17.7 3e-07 30.2 0.7 6.8 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP00819.1 - 3.6e-11 43.4 6.0 0.35 11.6 0.0 7.0 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFP00819.1 - 7.7e-11 41.1 8.1 0.022 14.3 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFP00819.1 - 2.7e-10 39.7 17.0 0.00063 19.3 0.6 7.6 4 3 5 9 9 9 4 TPR repeat Apc3 PF12895.2 KFP00819.1 - 1.5e-09 37.8 16.5 2e-05 24.6 1.8 5.9 4 3 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFP00819.1 - 1.6e-06 28.1 20.7 0.25 11.8 0.1 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat BTAD PF03704.12 KFP00819.1 - 8.4e-06 26.1 6.7 0.18 12.1 0.1 4.8 4 1 0 4 4 4 2 Bacterial transcriptional activator domain TPR_8 PF13181.1 KFP00819.1 - 3.6e-05 23.2 12.1 0.46 10.3 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP00819.1 - 0.00023 20.9 7.7 0.72 9.7 0.0 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 KFP00819.1 - 0.00069 19.4 0.0 28 4.9 0.0 5.3 5 0 0 5 5 5 0 PPR repeat TPR_7 PF13176.1 KFP00819.1 - 0.00071 19.1 9.8 10 6.1 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFP00819.1 - 0.0081 16.2 2.0 21 5.6 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR_2 PF13041.1 KFP00819.1 - 0.018 14.9 0.1 33 4.5 0.0 4.6 5 0 0 5 5 5 0 PPR repeat family Dishevelled PF02377.10 KFP00819.1 - 0.047 13.9 0.1 0.21 11.8 0.1 2.1 1 0 0 1 1 1 0 Dishevelled specific domain CorA PF01544.13 KFP00819.1 - 0.14 11.2 4.9 0.024 13.6 0.5 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TPR_10 PF13374.1 KFP00819.1 - 0.31 11.0 4.0 19 5.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Arf PF00025.16 KFP00820.1 - 3.9e-39 133.6 0.0 4.4e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFP00820.1 - 1.5e-12 47.0 0.1 1.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFP00820.1 - 1.9e-10 41.2 0.0 3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFP00820.1 - 2e-10 40.2 0.0 2.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFP00820.1 - 1e-07 31.3 0.0 1.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFP00820.1 - 0.00013 20.7 0.2 0.0015 17.2 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.1 KFP00820.1 - 0.00087 19.3 0.2 0.0023 17.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KFP00820.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFP00820.1 - 0.0015 18.6 0.2 0.0032 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFP00820.1 - 0.023 14.8 0.1 0.058 13.5 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KFP00820.1 - 0.029 13.9 0.3 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 KFP00820.1 - 0.072 12.5 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KFP00820.1 - 0.082 12.5 0.6 0.85 9.2 0.4 2.1 1 1 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 KFP00820.1 - 0.097 12.1 0.0 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KFP00820.1 - 0.1 12.3 0.2 0.68 9.7 0.0 2.0 1 1 1 2 2 2 0 Dynamin family DUF2332 PF10094.4 KFP00820.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Homeobox PF00046.24 KFP00821.1 - 4.3e-10 39.0 0.1 5.1e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Homeobox domain Colicin_Pyocin PF01320.13 KFP00821.1 - 0.0047 16.7 0.0 0.0057 16.4 0.0 1.1 1 0 0 1 1 1 1 Colicin immunity protein / pyocin immunity protein Homez PF11569.3 KFP00821.1 - 0.053 12.5 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Kazal_1 PF00050.16 KFP00822.1 - 3.1e-13 49.5 5.8 3.2e-13 49.4 4.0 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFP00822.1 - 1.9e-10 40.4 4.6 2.6e-10 40.0 3.2 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DSPc PF00782.15 KFP00823.1 - 1.6e-44 150.7 0.2 2.1e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFP00823.1 - 2.2e-07 30.4 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KFP00823.1 - 2.8e-06 27.6 0.0 5.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 KFP00823.1 - 0.026 14.5 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 KFP00823.1 - 0.068 12.6 0.2 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF3678 PF12435.3 KFP00823.1 - 1.4 8.5 7.1 0.22 11.1 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Ank_2 PF12796.2 KFP00824.1 - 1.9e-154 502.4 69.2 2.6e-21 75.7 0.1 9.8 3 3 7 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KFP00824.1 - 6.7e-138 442.2 50.1 6.9e-12 44.5 0.1 18.5 18 1 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.1 KFP00824.1 - 2.8e-111 361.0 52.6 1.3e-12 47.4 0.3 15.0 5 5 10 15 15 15 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP00824.1 - 1.8e-110 359.5 31.4 1.6e-14 53.9 0.2 15.2 8 5 8 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP00824.1 - 1.5e-94 300.3 37.2 6.2e-08 32.1 0.1 18.4 19 0 0 19 19 19 15 Ankyrin repeat PARP PF00644.15 KFP00824.1 - 7.6e-28 97.3 3.4 1.7e-25 89.6 2.4 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.12 KFP00824.1 - 6.1e-15 54.8 0.2 1.4e-14 53.7 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP00824.1 - 3.5e-12 46.3 0.5 8.2e-12 45.1 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Shigella_OspC PF06128.6 KFP00824.1 - 0.00022 20.8 0.8 15 4.9 0.0 5.1 6 0 0 6 6 6 1 Shigella flexneri OspC protein Vps39_1 PF10366.4 KFP00824.1 - 0.0033 17.4 1.4 5.4 7.0 0.0 3.9 4 1 1 5 5 5 2 Vacuolar sorting protein 39 domain 1 LRR_4 PF12799.2 KFP00825.1 - 5.1e-35 118.5 14.5 1.9e-08 33.7 1.7 5.6 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP00825.1 - 9.1e-27 92.6 21.2 1.4e-08 34.3 1.4 5.0 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 KFP00825.1 - 1.1e-19 67.4 22.3 0.05 13.6 0.1 9.9 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_7 PF13504.1 KFP00825.1 - 1.9e-10 39.2 23.8 0.67 10.3 0.2 9.8 9 0 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 KFP00825.1 - 0.0015 18.3 20.1 1.4 9.2 0.1 7.7 7 1 1 8 8 8 2 Leucine Rich repeat RNase_T PF00929.19 KFP00826.1 - 4.7e-27 95.2 0.0 1.7e-26 93.4 0.0 1.8 2 0 0 2 2 2 1 Exonuclease SAP PF02037.22 KFP00826.1 - 8.9e-08 31.4 0.7 1.7e-07 30.5 0.5 1.5 1 0 0 1 1 1 1 SAP domain CBM_21 PF03370.8 KFP00827.1 - 8.7e-34 115.9 1.5 1.2e-33 115.3 0.6 1.6 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit Ldl_recept_a PF00057.13 KFP00828.1 - 5.6e-43 144.5 97.6 6.4e-10 38.7 6.4 7.1 7 0 0 7 7 7 6 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 KFP00828.1 - 8.3e-19 67.6 8.2 2.5e-07 30.8 0.0 5.8 5 1 0 5 5 5 4 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFP00828.1 - 8.4e-12 45.0 33.4 8.1e-08 32.2 6.4 7.8 6 4 1 7 7 7 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFP00828.1 - 6.7e-08 32.4 3.7 6.7e-08 32.4 2.6 7.8 5 1 2 7 7 7 1 Calcium-binding EGF domain cEGF PF12662.2 KFP00828.1 - 2.6e-07 30.1 7.6 6.3e-05 22.5 0.5 4.5 4 0 0 4 4 4 2 Complement Clr-like EGF-like PMP22_Claudin PF00822.15 KFP00829.1 - 1.1e-13 51.2 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP00829.1 - 1.8e-06 27.7 0.8 4.8e-06 26.3 0.5 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 KFP00829.1 - 0.019 14.5 0.0 0.47 9.9 0.0 2.1 1 1 1 2 2 2 0 SUR7/PalI family Clc-like PF07062.7 KFP00829.1 - 0.066 12.4 0.0 0.066 12.4 0.0 1.9 3 0 0 3 3 3 0 Clc-like DUF2892 PF11127.3 KFP00829.1 - 1.1 9.1 11.1 0.14 12.0 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) NfeD PF01957.13 KFP00829.1 - 9.2 6.3 6.5 22 5.1 3.4 2.3 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding AHS2 PF02626.10 KFP00830.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 RnaseA PF00074.15 KFP00831.1 - 0.00016 21.9 0.1 0.00017 21.8 0.1 1.0 1 0 0 1 1 1 1 Pancreatic ribonuclease Ribosomal_S3Ae PF01015.13 KFP00832.1 - 1.2e-81 272.7 5.6 1.3e-81 272.5 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 KFP00832.1 - 0.0042 16.4 0.2 0.018 14.3 0.0 2.1 1 1 1 2 2 2 1 Partial alpha/beta-hydrolase lipase region GatB_N PF02934.10 KFP00834.1 - 4.9e-104 347.2 0.0 7e-104 346.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KFP00834.1 - 9.7e-39 132.4 8.9 1.7e-38 131.6 6.2 1.4 1 0 0 1 1 1 1 GatB domain Pox_VLTF3 PF04947.9 KFP00834.1 - 0.05 13.1 2.2 0.039 13.4 0.4 1.6 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like WD40 PF00400.27 KFP00835.1 - 2.4e-58 192.0 30.7 8.8e-11 41.2 0.3 8.7 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KFP00835.1 - 3.6e-17 61.7 16.9 0.0014 16.9 0.3 6.9 1 1 5 6 6 6 6 Nucleoporin Nup120/160 F-box-like PF12937.2 KFP00835.1 - 2.3e-13 49.6 1.6 4e-13 48.8 1.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFP00835.1 - 7e-09 35.1 0.3 1.2e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KFP00835.1 - 3e-06 26.8 5.4 8e-05 22.2 2.8 3.9 2 1 0 2 2 2 1 PQQ-like domain CDtoxinA PF03498.9 KFP00835.1 - 0.0053 16.1 2.5 0.54 9.6 0.2 3.4 2 1 1 3 3 3 1 Cytolethal distending toxin A/C family Nop14 PF04147.7 KFP00835.1 - 0.057 11.3 20.9 0.076 10.9 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 KFP00835.1 - 2.3 8.2 13.5 0.11 12.6 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) TFIIA PF03153.8 KFP00835.1 - 6.9 6.4 27.3 11 5.8 18.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM154 PF15102.1 KFP00836.1 - 3.9e-36 123.9 1.7 5.3e-36 123.5 1.2 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 KFP00836.1 - 1.6e-05 24.8 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 KFP00836.1 - 0.0038 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family CCSMST1 PF15013.1 KFP00836.1 - 0.058 13.3 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 CCSMST1 family BatD PF13584.1 KFP00836.1 - 0.059 11.9 0.0 0.063 11.8 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF4448 PF14610.1 KFP00836.1 - 0.094 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PspB PF06667.7 KFP00836.1 - 0.12 12.2 0.3 0.24 11.3 0.2 1.6 1 1 0 1 1 1 0 Phage shock protein B DDE_1 PF03184.14 KFP00837.1 - 2.6e-49 167.2 0.0 5e-49 166.3 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KFP00837.1 - 1.1e-19 70.0 0.0 1.9e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KFP00837.1 - 4.9e-09 35.4 2.3 1.1e-08 34.3 1.6 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DDE_3 PF13358.1 KFP00837.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 KFP00837.1 - 0.002 17.6 0.0 0.036 13.7 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 KFP00837.1 - 0.014 15.2 0.3 0.054 13.4 0.0 2.1 2 0 0 2 2 2 0 Transposase CENP-B_dimeris PF09026.5 KFP00837.1 - 0.024 14.8 0.2 0.056 13.6 0.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Arfaptin PF06456.8 KFP00838.1 - 1.3e-81 273.3 9.0 1.6e-81 272.9 6.2 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR PF03114.13 KFP00838.1 - 0.0087 15.5 10.9 0.02 14.3 7.5 1.6 1 1 0 1 1 1 1 BAR domain NHL PF01436.16 KFP00839.1 - 2e-48 159.9 17.5 9.1e-10 37.9 0.1 6.5 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.14 KFP00839.1 - 1.3e-18 67.4 0.0 5.2e-18 65.4 0.0 2.1 1 0 0 1 1 1 1 Filamin/ABP280 repeat SGL PF08450.7 KFP00839.1 - 1.3e-11 44.3 3.3 5.8e-05 22.5 0.0 5.4 1 1 4 6 6 6 3 SMP-30/Gluconolaconase/LRE-like region zf-B_box PF00643.19 KFP00839.1 - 1.4e-10 40.8 3.2 1.4e-10 40.8 2.2 3.1 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4_2 PF13923.1 KFP00839.1 - 2.4e-08 33.8 10.8 2.4e-08 33.8 7.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP00839.1 - 4.2e-08 32.6 10.2 4.2e-08 32.6 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP00839.1 - 1.2e-07 31.3 8.7 1.2e-07 31.3 6.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP00839.1 - 1.3e-07 31.3 10.2 1.3e-07 31.3 7.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFP00839.1 - 2.1e-07 30.5 7.3 2.1e-07 30.5 5.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFP00839.1 - 1.5e-06 27.8 6.0 1.9e-06 27.5 2.4 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFP00839.1 - 6.1e-05 22.8 11.2 6.1e-05 22.8 7.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KFP00839.1 - 0.0054 16.5 1.4 0.014 15.2 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SBBP PF06739.6 KFP00839.1 - 0.0089 15.7 2.2 0.48 10.2 0.3 3.4 4 0 0 4 4 4 1 Beta-propeller repeat Big_1 PF02369.11 KFP00839.1 - 0.023 14.5 0.4 0.099 12.5 0.3 2.1 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Ldl_recept_b PF00058.12 KFP00839.1 - 0.039 14.2 0.0 20 5.5 0.0 3.8 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B IBR PF01485.16 KFP00839.1 - 0.76 9.6 13.5 0.052 13.4 0.8 3.0 2 1 1 3 3 3 0 IBR domain VCBS PF13517.1 KFP00839.1 - 2.2 8.7 7.4 29 5.1 0.0 4.4 2 1 3 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-RING_6 PF14835.1 KFP00839.1 - 3.8 7.3 12.0 0.028 14.2 2.3 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Mnd1 PF03962.10 KFP00840.1 - 3.5e-74 248.5 8.8 4e-74 248.3 6.1 1.0 1 0 0 1 1 1 1 Mnd1 family DivIC PF04977.10 KFP00840.1 - 3.3e-06 26.4 12.9 0.00088 18.7 1.0 3.4 1 1 2 3 3 3 3 Septum formation initiator Penicillinase_R PF03965.11 KFP00840.1 - 6.8e-06 26.1 1.6 8.5e-06 25.8 0.4 1.6 1 1 1 2 2 2 1 Penicillinase repressor TBPIP PF07106.8 KFP00840.1 - 0.00032 20.3 7.0 0.00047 19.7 4.8 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) S10_plectin PF03501.10 KFP00840.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain DsrD PF08679.6 KFP00840.1 - 0.04 13.9 0.2 0.04 13.9 0.2 2.3 2 1 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) TrmB PF01978.14 KFP00840.1 - 0.043 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF342 PF03961.8 KFP00840.1 - 0.044 12.1 5.2 0.063 11.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Allexi_40kDa PF05549.6 KFP00840.1 - 0.068 12.4 0.9 0.089 12.0 0.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF904 PF06005.7 KFP00840.1 - 0.11 12.8 14.7 1.2e+02 3.0 10.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 KFP00840.1 - 0.12 11.9 8.4 0.2 11.2 5.8 1.3 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 KFP00840.1 - 0.13 11.4 12.0 0.22 10.7 8.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KFP00840.1 - 0.13 11.2 9.4 0.18 10.8 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_2 PF07724.9 KFP00840.1 - 0.19 11.6 2.7 0.2 11.5 0.4 1.9 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_23 PF13476.1 KFP00840.1 - 0.63 10.3 10.7 1 9.6 7.4 1.3 1 0 0 1 1 1 0 AAA domain FemAB PF02388.11 KFP00840.1 - 1.4 7.5 8.7 1.8 7.1 6.0 1.2 1 0 0 1 1 1 0 FemAB family DivIVA PF05103.8 KFP00840.1 - 1.4 9.0 13.8 3.8 7.5 2.3 2.5 1 1 1 2 2 2 0 DivIVA protein Atg14 PF10186.4 KFP00840.1 - 2.3 7.0 10.7 6.3 5.6 6.8 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 KFP00840.1 - 7.7 6.5 15.6 2.6 8.1 3.1 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 KFP00840.1 - 8.4 6.8 12.3 2.7 8.4 2.4 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3651 PF12371.3 KFP00841.1 - 7.6e-09 35.4 3.5 3.4e-06 26.9 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3651) LRR_8 PF13855.1 KFP00842.1 - 1.2e-34 117.8 43.5 4.1e-13 48.8 5.4 8.0 4 2 4 8 8 8 8 Leucine rich repeat TIR PF01582.15 KFP00842.1 - 2.8e-34 117.5 1.3 5.1e-34 116.7 0.9 1.4 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 KFP00842.1 - 5.3e-22 76.9 53.7 4.9e-05 22.8 0.9 10.0 5 4 6 11 11 11 8 Leucine Rich repeats (2 copies) TIR_2 PF13676.1 KFP00842.1 - 3.5e-13 49.5 0.0 1.3e-12 47.7 0.0 2.1 1 0 0 1 1 1 1 TIR domain LRR_1 PF00560.28 KFP00842.1 - 1.2e-10 39.8 43.7 0.11 12.6 0.2 13.6 10 3 1 11 11 11 4 Leucine Rich Repeat LRR_9 PF14580.1 KFP00842.1 - 0.0052 16.3 7.2 0.2 11.2 0.2 4.1 2 2 1 4 4 4 2 Leucine-rich repeat DUF1863 PF08937.6 KFP00842.1 - 0.0072 16.3 0.2 0.053 13.5 0.1 2.3 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) tRNA_bind_2 PF13725.1 KFP00842.1 - 0.012 15.7 2.2 0.27 11.3 0.3 3.3 2 1 0 2 2 2 0 Possible tRNA binding domain LRR_6 PF13516.1 KFP00842.1 - 0.071 13.2 42.6 3 8.1 0.1 11.3 11 2 1 12 12 12 0 Leucine Rich repeat LRR_7 PF13504.1 KFP00842.1 - 0.093 12.9 40.3 0.51 10.7 0.0 10.8 13 0 0 13 13 13 0 Leucine rich repeat Fz PF01392.17 KFP00843.1 - 5.6e-33 113.7 4.3 1.2e-32 112.6 3.0 1.6 1 0 0 1 1 1 1 Fz domain NTR PF01759.16 KFP00843.1 - 2e-15 56.3 0.2 3.2e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Chlam_OMP6 PF03504.8 KFP00843.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 Cadherin PF00028.12 KFP00844.1 - 1e-127 416.7 14.5 2.1e-22 79.1 0.0 8.3 8 0 0 8 8 8 8 Cadherin domain Cadherin_2 PF08266.7 KFP00844.1 - 3.6e-09 36.0 0.0 3.5 7.2 0.0 7.4 7 1 0 7 7 7 3 Cadherin-like WD40 PF00400.27 KFP00845.1 - 1.2e-54 180.2 20.1 1.9e-11 43.3 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFP00845.1 - 4.8e-06 25.5 0.1 0.34 9.6 0.0 3.4 1 1 2 3 3 3 3 Nup133 N terminal like BBS2_Mid PF14783.1 KFP00845.1 - 0.00037 20.2 0.2 3.4 7.4 0.0 4.4 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KFP00845.1 - 0.00048 18.3 5.9 0.079 11.0 1.0 3.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFP00845.1 - 0.058 12.8 1.3 2.8 7.3 0.9 2.6 1 1 0 1 1 1 0 PQQ-like domain Fibrinogen_C PF00147.13 KFP00846.1 - 1.8e-111 371.3 14.5 2.5e-111 370.9 10.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.5 KFP00846.1 - 3.3e-41 140.8 2.2 4.5e-41 140.3 1.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF1465 PF07323.7 KFP00846.1 - 0.026 14.0 0.2 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Bacillus_HBL PF05791.6 KFP00846.1 - 0.49 9.7 6.0 5.2 6.3 4.1 2.1 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.7 KFP00846.1 - 0.7 9.7 2.5 13 5.6 0.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KFP00847.1 - 1.1e-43 148.8 6.4 1.2e-43 148.7 3.8 1.5 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family TcdB_N PF12918.2 KFP00847.1 - 0.018 15.1 2.4 0.066 13.2 1.6 2.0 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain DUF3610 PF12272.3 KFP00847.1 - 0.022 14.4 0.1 0.049 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) DUF1672 PF07901.6 KFP00847.1 - 0.086 11.8 3.7 0.53 9.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1672) DUF4407 PF14362.1 KFP00847.1 - 0.1 11.5 3.7 1.1 8.1 2.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cor1 PF04803.7 KFP00847.1 - 0.29 10.8 6.6 0.94 9.2 4.6 1.8 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region ING PF12998.2 KFP00847.1 - 0.87 9.8 8.6 2.6 8.3 1.5 2.5 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.7 KFP00847.1 - 1.1 9.0 4.8 3.6 7.3 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1446 PF07287.6 KFP00848.1 - 1.3e-102 343.0 0.0 1.4e-102 342.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) LRAT PF04970.8 KFP00849.1 - 1.1e-24 86.7 0.0 1.5e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase RRM_1 PF00076.17 KFP00850.1 - 1.2e-36 124.1 1.4 3.2e-14 52.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00850.1 - 3e-29 100.7 0.7 7.1e-10 38.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.1 KFP00850.1 - 6.1e-26 90.5 0.1 5.5e-25 87.4 0.1 2.2 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_5 PF13893.1 KFP00850.1 - 6.2e-18 64.3 0.4 3.2e-06 26.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFP00850.1 - 0.0056 16.3 0.0 1.2 8.9 0.0 3.2 1 1 1 3 3 3 1 Limkain b1 7tm_1 PF00001.16 KFP00851.1 - 5.7e-54 182.9 14.5 7.8e-54 182.5 10.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00851.1 - 2.9e-15 56.1 13.5 3.9e-15 55.6 9.4 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP00851.1 - 0.00019 20.6 8.2 0.00019 20.6 5.7 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4131 PF13567.1 KFP00851.1 - 0.055 12.8 0.1 0.055 12.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4207 PF13904.1 KFP00852.1 - 5.8e-05 22.5 87.8 0.013 14.8 33.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4207) HNOBA PF07701.9 KFP00853.1 - 6e-62 208.7 1.8 6e-61 205.4 1.3 2.3 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.15 KFP00853.1 - 3e-61 205.9 0.0 5.3e-61 205.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.10 KFP00853.1 - 1.4e-06 27.9 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Heme NO binding HNOBA PF07701.9 KFP00854.1 - 7.2e-73 244.4 0.0 1.3e-72 243.6 0.0 1.4 1 0 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.15 KFP00854.1 - 2.5e-65 219.2 0.0 3.8e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.10 KFP00854.1 - 3.8e-63 212.0 0.1 5.8e-63 211.4 0.0 1.3 1 0 0 1 1 1 1 Heme NO binding Trp_dioxygenase PF03301.8 KFP00855.1 - 1.7e-164 547.0 6.7 2e-164 546.7 4.7 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Peptidase_C1 PF00112.18 KFP00856.1 - 1.2e-58 198.6 3.6 1.4e-58 198.3 2.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFP00856.1 - 9e-07 27.7 0.2 0.0012 17.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.7 KFP00856.1 - 0.022 15.0 0.1 0.045 14.0 0.1 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Peptidase_C39_2 PF13529.1 KFP00856.1 - 0.058 13.7 0.6 0.2 12.0 0.4 1.8 1 1 0 1 1 1 0 Peptidase_C39 like family rve PF00665.21 KFP00857.1 - 3.8e-25 88.3 0.1 6.1e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 KFP00857.1 - 1.3e-13 50.1 2.2 2.4e-13 49.3 1.5 1.4 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.19 KFP00857.1 - 3.3e-11 43.6 0.0 8.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 RNase H DDE_Tnp_IS240 PF13610.1 KFP00857.1 - 0.00046 20.1 0.0 0.00087 19.2 0.0 1.5 1 0 0 1 1 1 1 DDE domain RVT_1 PF00078.22 KFP00858.1 - 7.5e-29 100.6 0.0 9.8e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFP00858.1 - 0.044 13.3 0.3 0.087 12.4 0.2 1.6 1 0 0 1 1 1 0 Reverse transcriptase thumb domain dUTPase PF00692.14 KFP00859.1 - 4.1e-19 68.3 0.1 8.7e-19 67.2 0.0 1.5 1 1 1 2 2 2 1 dUTPase RVP PF00077.15 KFP00859.1 - 0.016 15.1 0.2 0.052 13.4 0.0 1.9 2 1 0 2 2 2 0 Retroviral aspartyl protease Yae1_N PF09811.4 KFP00860.1 - 9.7e-17 60.2 70.2 0.15 11.6 15.4 6.9 2 2 0 2 2 2 1 Essential protein Yae1, N terminal CUB PF00431.15 KFP00861.1 - 1.6e-17 63.5 0.0 2.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.12 KFP00861.1 - 7.3e-13 48.4 12.0 1.2e-12 47.8 8.3 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain Neur_chan_LBD PF02931.18 KFP00862.1 - 6.5e-55 185.6 0.2 8.3e-55 185.2 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP00862.1 - 4.9e-38 131.3 2.9 1.1e-36 126.8 2.0 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region NfeD PF01957.13 KFP00862.1 - 0.06 13.4 0.1 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding FAM198 PF15051.1 KFP00863.1 - 3.3e-153 509.1 0.5 4e-153 508.8 0.4 1.0 1 0 0 1 1 1 1 FAM198 protein DUF1632 PF07857.7 KFP00864.1 - 1.6e-92 309.3 3.2 1.6e-92 309.3 2.2 1.8 1 1 1 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 KFP00864.1 - 5.1e-12 45.4 11.8 5.3e-11 42.1 2.2 2.4 2 0 0 2 2 2 2 Sugar transport protein LRR_8 PF13855.1 KFP00865.1 - 2.3e-56 187.3 65.1 2e-14 53.0 3.4 5.5 1 1 6 7 7 7 7 Leucine rich repeat 7tm_1 PF00001.16 KFP00865.1 - 5e-28 97.9 16.7 7.6e-28 97.3 11.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.2 KFP00865.1 - 3.1e-26 90.4 32.7 7.7e-08 31.7 1.9 6.7 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP00865.1 - 1.5e-09 36.5 30.0 0.94 9.7 0.0 9.9 10 0 0 10 10 10 4 Leucine Rich Repeat Ldl_recept_a PF00057.13 KFP00865.1 - 5.1e-08 32.6 6.3 5.1e-08 32.6 4.3 1.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRR_9 PF14580.1 KFP00865.1 - 3.5e-06 26.6 10.4 0.22 11.0 0.5 3.7 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 KFP00865.1 - 2.9e-05 23.7 20.8 12 6.3 0.1 8.7 8 1 1 9 9 9 1 Leucine Rich repeat LRR_7 PF13504.1 KFP00865.1 - 3.6e-05 23.2 20.3 2.2 8.8 0.1 9.1 9 0 0 9 9 9 2 Leucine rich repeat LRRNT PF01462.13 KFP00865.1 - 0.00015 21.1 0.1 0.00038 19.8 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain ETF_QO PF05187.8 KFP00866.1 - 1.1e-43 147.7 0.0 1.9e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KFP00866.1 - 9.9e-11 41.1 0.8 2.1e-05 23.6 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFP00866.1 - 2e-08 33.4 0.6 3.2e-05 22.9 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KFP00866.1 - 8.7e-08 31.5 0.0 1.8e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KFP00866.1 - 5.6e-07 29.4 0.1 3.4e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFP00866.1 - 2.4e-05 23.5 0.1 5.4e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFP00866.1 - 2.9e-05 24.0 0.2 5.2e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFP00866.1 - 3.5e-05 23.6 0.0 0.00014 21.6 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFP00866.1 - 8.7e-05 21.6 0.1 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KFP00866.1 - 0.00014 20.5 0.4 0.0002 19.9 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KFP00866.1 - 0.00072 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFP00866.1 - 0.0019 17.3 0.1 0.003 16.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KFP00866.1 - 0.003 16.2 0.0 0.023 13.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 KFP00866.1 - 0.016 15.5 0.1 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KFP00866.1 - 0.021 15.1 0.5 0.061 13.7 0.3 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 KFP00866.1 - 0.034 12.9 0.2 0.055 12.3 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KFP00866.1 - 0.039 12.8 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pro_isomerase PF00160.16 KFP00867.1 - 1.9e-46 158.0 0.7 2.1e-46 157.9 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FNIP_M PF14637.1 KFP00868.1 - 2.2e-89 299.0 0.6 4.1e-89 298.1 0.4 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 KFP00868.1 - 1.4e-70 236.5 0.4 3.6e-70 235.2 0.3 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 KFP00868.1 - 3.7e-38 130.9 0.9 3.7e-38 130.9 0.6 3.0 3 1 0 3 3 3 1 Folliculin-interacting protein N-terminus RasGEF_N PF00618.15 KFP00869.1 - 1.1e-17 63.9 0.1 3.1e-17 62.5 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.18 KFP00869.1 - 5.2e-11 42.8 0.0 1.4e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain cNMP_binding PF00027.24 KFP00869.1 - 7.4e-11 41.7 0.0 7.3e-06 25.7 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain PDZ PF00595.19 KFP00869.1 - 1.1e-10 41.4 0.0 2.6e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP00869.1 - 4.1e-05 23.3 0.0 0.00013 21.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain I-set PF07679.11 KFP00870.1 - 2.2e-26 91.5 0.0 4e-15 55.4 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP00870.1 - 2.1e-22 79.0 0.1 4.5e-10 39.5 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP00870.1 - 4.6e-17 62.2 0.2 2.2e-09 37.6 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP00870.1 - 5.2e-12 45.7 0.0 0.00011 22.2 0.0 3.1 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP00870.1 - 6.6e-09 35.6 0.5 5.5e-05 23.0 0.0 3.5 2 1 1 3 3 3 2 Immunoglobulin V-set domain Kazal_2 PF07648.10 KFP00870.1 - 5.3e-08 32.6 4.8 5.3e-08 32.6 3.3 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP00870.1 - 7.2e-06 25.9 11.1 2.2e-05 24.3 7.7 1.9 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.27 KFP00870.1 - 0.0018 17.4 0.2 0.0066 15.6 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFP00870.1 - 0.004 17.2 4.9 0.0073 16.4 2.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP00870.1 - 0.0044 17.0 1.4 0.011 15.8 0.9 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_6 PF13405.1 KFP00870.1 - 0.0077 16.0 0.7 0.13 12.1 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain DUF3049 PF11250.3 KFP00871.1 - 0.2 11.4 0.9 2.1 8.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3049) Gar1 PF04410.9 KFP00872.1 - 1.8e-39 134.6 0.4 2.7e-39 134.0 0.3 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region 7tm_1 PF00001.16 KFP00873.1 - 2.5e-58 197.2 20.8 3.2e-58 196.8 14.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP00873.1 - 3.5e-10 39.4 20.0 5.4e-10 38.8 13.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.3 KFP00873.1 - 0.031 13.8 10.3 0.086 12.3 7.2 1.7 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 PLAC8 PF04749.12 KFP00873.1 - 1.2 9.7 8.7 3.3 8.3 0.0 3.2 2 1 1 3 3 3 0 PLAC8 family DUF2962 PF11176.3 KFP00874.1 - 2.5e-44 150.5 8.8 3e-44 150.2 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) RINGv PF12906.2 KFP00875.1 - 6.9e-16 58.0 16.1 1.5e-15 56.9 11.1 1.6 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.7 KFP00875.1 - 0.035 13.8 0.3 0.05 13.3 0.2 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component 7tm_7 PF08395.7 KFP00875.1 - 0.34 9.8 3.0 0.35 9.8 1.5 1.4 1 1 1 2 2 2 0 7tm Chemosensory receptor PDEase_I PF00233.14 KFP00876.1 - 3.2e-32 112.1 1.6 3.4e-32 112.0 1.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KFP00876.1 - 0.074 13.0 0.2 0.081 12.9 0.1 1.1 1 0 0 1 1 1 0 HD domain Yae1_N PF09811.4 KFP00878.1 - 1.2e-19 69.5 62.0 1.5e+04 -22.8 43.0 5.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal TMEM192 PF14802.1 KFP00879.1 - 1.5e-79 266.1 2.4 1.7e-79 265.9 1.7 1.0 1 0 0 1 1 1 1 TMEM192 family Fig1 PF12351.3 KFP00879.1 - 0.027 14.3 1.0 0.037 13.9 0.3 1.4 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 zf-DHHC PF01529.15 KFP00879.1 - 0.41 10.0 5.6 0.13 11.6 1.5 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase Kelch_1 PF01344.20 KFP00880.1 - 2.2e-81 267.2 19.3 6.1e-15 54.4 0.6 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFP00880.1 - 2e-42 141.6 4.2 9.2e-08 31.9 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFP00880.1 - 1.3e-33 114.3 13.6 2.2e-06 27.6 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFP00880.1 - 4.4e-32 110.3 0.1 9.5e-32 109.2 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFP00880.1 - 6.1e-32 108.1 10.2 7.5e-06 25.5 0.1 6.4 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 KFP00880.1 - 3.6e-30 103.8 0.8 1.4e-29 101.9 0.5 2.1 1 1 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFP00880.1 - 3.9e-28 96.9 8.6 6.6e-05 22.6 0.1 6.3 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP00880.1 - 1.2e-07 31.5 16.5 0.3 11.0 0.1 5.4 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.1 KFP00880.1 - 0.005 17.0 11.1 1.5 9.1 0.0 5.0 5 0 0 5 5 5 1 PQQ-like domain Ashwin PF15323.1 KFP00880.1 - 0.11 12.4 0.5 0.19 11.7 0.3 1.2 1 0 0 1 1 1 0 Developmental protein FA_hydroxylase PF04116.8 KFP00881.1 - 3.8e-15 56.2 17.2 3.8e-15 56.2 11.9 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M14 PF00246.19 KFP00882.1 - 1.5e-63 215.0 0.0 1.8e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 KFP00882.1 - 1.2e-15 57.3 0.0 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFP00882.1 - 1.5e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 KFP00882.1 - 0.055 12.3 0.0 0.12 11.1 0.0 1.5 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 KFP00882.1 - 0.17 10.9 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) CUB PF00431.15 KFP00883.1 - 1.1e-187 611.2 5.7 2.6e-40 136.8 0.2 5.3 5 0 0 5 5 5 5 CUB domain Astacin PF01400.19 KFP00883.1 - 4.1e-73 244.8 0.1 9.3e-73 243.6 0.0 1.6 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.1 KFP00883.1 - 1.1e-19 70.2 28.3 1.1e-09 38.2 6.7 3.0 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFP00883.1 - 2.3e-12 46.6 30.7 3.6e-07 30.0 5.9 2.9 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.2 KFP00883.1 - 4.9e-09 35.6 6.7 6.2e-05 22.5 0.9 3.3 2 0 0 2 2 2 2 Complement Clr-like EGF-like CUB_2 PF02408.15 KFP00883.1 - 1.8e-05 24.2 4.0 0.46 10.0 0.0 4.4 4 0 0 4 4 4 2 CUB-like domain EGF_3 PF12947.2 KFP00883.1 - 3.8e-05 23.5 24.6 0.0006 19.7 3.5 3.4 2 1 1 3 3 3 2 EGF domain Peptidase_M10 PF00413.19 KFP00883.1 - 0.0028 17.3 0.1 0.55 9.9 0.1 2.6 2 0 0 2 2 2 1 Matrixin Reprolysin_2 PF13574.1 KFP00883.1 - 0.0061 16.6 0.1 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP00883.1 - 0.018 14.5 0.1 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SPARC_Ca_bdg PF10591.4 KFP00884.1 - 3.4e-32 110.8 1.7 6.2e-32 109.9 1.2 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.13 KFP00884.1 - 3.7e-15 55.0 6.9 3.7e-15 55.0 4.8 3.4 4 0 0 4 4 4 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.10 KFP00884.1 - 3.3e-10 39.7 6.7 3.3e-10 39.7 4.7 2.9 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP00884.1 - 2.1e-08 34.0 8.3 2.1e-08 34.0 5.7 3.9 4 1 0 4 4 4 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.1 KFP00884.1 - 0.29 11.1 5.3 2.8 8.0 0.1 3.6 4 0 0 4 4 4 0 EF-hand domain Annexin PF00191.15 KFP00885.1 - 2.5e-80 264.3 7.5 1.4e-20 72.9 0.1 4.0 4 0 0 4 4 4 4 Annexin GETHR PF05671.6 KFP00886.1 - 0.2 10.7 3.9 0.39 9.9 1.5 2.2 1 1 1 2 2 2 0 GETHR pentapeptide repeat (5 copies) Pox_Ag35 PF03286.9 KFP00887.1 - 0.012 15.1 1.1 0.015 14.8 0.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-B_box PF00643.19 KFP00887.1 - 0.034 14.0 0.7 0.034 14.0 0.5 1.9 2 0 0 2 2 2 0 B-box zinc finger zf-A20 PF01754.11 KFP00887.1 - 0.037 13.5 0.2 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 A20-like zinc finger CAP_N PF01213.14 KFP00887.1 - 0.063 12.5 0.4 0.073 12.3 0.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FlbD PF06289.6 KFP00887.1 - 0.093 12.1 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein (FlbD) I-set PF07679.11 KFP00888.1 - 2.5e-109 357.3 0.0 1.3e-21 76.2 0.0 6.4 5 1 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP00888.1 - 1.4e-57 191.7 0.2 8.8e-10 38.5 0.0 6.0 5 0 0 5 5 5 5 Immunoglobulin domain Ig_3 PF13927.1 KFP00888.1 - 2.1e-39 133.7 2.5 2.9e-07 30.8 0.0 6.8 6 0 0 6 6 6 5 Immunoglobulin domain ig PF00047.20 KFP00888.1 - 2.2e-28 98.1 0.3 8e-05 22.6 0.0 6.2 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFP00888.1 - 8.1e-23 80.4 5.0 0.0034 17.2 0.0 7.9 6 2 0 6 6 6 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP00888.1 - 1.2e-15 57.1 1.3 0.0073 16.1 0.0 6.6 6 1 0 6 6 6 5 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 KFP00888.1 - 0.00079 19.3 0.0 0.41 10.5 0.0 3.9 5 0 0 5 5 5 1 Natural killer cell receptor 2B4 BiPBP_C PF06832.7 KFP00888.1 - 0.0039 17.0 0.0 2.9 7.8 0.0 3.8 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family C2-set PF05790.10 KFP00888.1 - 0.004 17.1 0.4 6.6 6.7 0.1 4.2 4 0 0 4 4 4 1 Immunoglobulin C2-set domain adh_short PF00106.20 KFP00889.1 - 5.7e-35 120.6 1.2 8.7e-35 120.1 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFP00889.1 - 3e-30 105.7 0.0 3.6e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFP00889.1 - 6e-17 61.8 0.9 1.1e-16 61.0 0.4 1.5 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KFP00889.1 - 0.00032 20.7 0.1 0.00058 19.9 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFP00889.1 - 0.0011 18.4 0.1 0.0035 16.8 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family SH3_9 PF14604.1 KFP00890.1 - 1.1e-58 194.5 2.5 1.8e-16 59.4 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.23 KFP00890.1 - 6e-50 166.4 2.0 3.6e-12 45.4 0.0 4.3 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.12 KFP00890.1 - 8.4e-36 121.2 1.8 2.6e-09 36.4 0.1 4.4 4 0 0 4 4 4 4 Variant SH3 domain zf-C3HC4 PF00097.20 KFP00890.1 - 3.5e-09 36.1 7.0 6.7e-09 35.2 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP00890.1 - 7.8e-09 35.4 8.2 1.6e-08 34.4 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP00890.1 - 3.3e-08 33.2 8.0 7.2e-08 32.1 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KFP00890.1 - 2.9e-07 30.0 5.7 6.6e-07 28.9 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFP00890.1 - 3.9e-07 29.6 6.8 7.2e-07 28.8 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP00890.1 - 3.6e-06 26.5 8.7 6.5e-06 25.7 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP00890.1 - 7.9e-05 22.4 7.8 0.00015 21.5 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFP00890.1 - 0.00017 21.0 4.8 0.00017 21.0 3.3 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 KFP00890.1 - 0.0024 17.3 5.5 0.005 16.3 3.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFP00890.1 - 0.12 11.8 2.6 0.3 10.6 1.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Trm112p PF03966.11 KFP00890.1 - 1.5 9.2 5.9 4.5 7.7 4.1 1.9 1 0 0 1 1 1 0 Trm112p-like protein Voltage_CLC PF00654.15 KFP00892.1 - 4.3e-100 335.1 21.0 6.3e-100 334.6 14.6 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 KFP00892.1 - 2.3e-15 56.0 0.6 3.6e-09 36.2 0.1 2.4 2 0 0 2 2 2 2 CBS domain DUF2228 PF10228.4 KFP00893.1 - 2.1e-103 345.2 0.2 3e-103 344.7 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) DUF2115 PF09888.4 KFP00893.1 - 0.2 11.7 2.3 4.9 7.2 0.7 2.2 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) I-set PF07679.11 KFP00894.1 - 1.1e-14 54.0 0.0 2.4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP00894.1 - 1.4e-10 41.1 0.1 2.7e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP00894.1 - 2.6e-08 33.8 0.1 8.6e-08 32.2 0.1 2.0 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP00894.1 - 1.6e-07 31.6 1.2 7e-07 29.6 0.9 2.0 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP00894.1 - 2.6e-06 27.3 0.6 6.7e-06 25.9 0.2 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain DUF4446 PF14584.1 KFP00894.1 - 0.044 13.6 0.5 0.075 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TSP_1 PF00090.14 KFP00895.1 - 3.8e-28 97.3 72.9 5e-08 32.9 3.6 7.0 5 1 1 6 6 6 6 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 KFP00895.1 - 4.6e-17 61.9 0.0 6.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 PLAC PF08686.6 KFP00895.1 - 2.7e-11 43.5 14.1 1.5e-10 41.1 9.8 2.4 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Neur_chan_LBD PF02931.18 KFP00896.1 - 1.2e-71 240.3 1.1 1.5e-71 239.9 0.8 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP00896.1 - 1.5e-62 211.6 0.0 1.8e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region AHS1 PF02682.11 KFP00897.1 - 0.89 8.9 6.0 5.1 6.5 1.0 2.6 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 Baculo_PEP_C PF04513.7 KFP00897.1 - 1 9.1 23.3 1.1 9.1 0.7 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cyclin_N PF00134.18 KFP00898.1 - 3.1e-44 149.6 0.3 1.8e-43 147.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP00898.1 - 6e-31 106.8 1.6 1.8e-30 105.2 0.9 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain RNF111_N PF15303.1 KFP00899.1 - 3.7e-108 361.1 25.0 3.7e-108 361.1 17.3 2.5 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus zf-RING_2 PF13639.1 KFP00899.1 - 7.3e-15 54.5 6.2 7.3e-15 54.5 4.3 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFP00899.1 - 5.3e-08 32.4 3.9 5.3e-08 32.4 2.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP00899.1 - 2e-07 30.8 6.7 2e-07 30.8 4.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP00899.1 - 6.8e-07 29.3 5.2 6.8e-07 29.3 3.6 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP00899.1 - 1.5e-06 27.7 5.9 1.5e-06 27.7 4.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP00899.1 - 4.9e-06 26.1 3.9 4.9e-06 26.1 2.7 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFP00899.1 - 0.052 13.3 5.8 0.11 12.2 2.7 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.17 KFP00900.1 - 1.2e-11 44.1 0.0 2.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00900.1 - 3.6e-11 42.8 0.0 1.3e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00900.1 - 1.6e-05 24.6 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Reprolysin_2 PF13574.1 KFP00901.1 - 1.5e-32 113.0 0.4 3.2e-32 111.9 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFP00901.1 - 2.8e-32 112.2 1.9 2.2e-31 109.3 0.1 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFP00901.1 - 1.5e-26 93.2 0.6 2.3e-26 92.6 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFP00901.1 - 7e-22 78.2 0.0 2.1e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KFP00901.1 - 1.6e-16 60.2 0.5 2.9e-16 59.4 0.3 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 KFP00901.1 - 9.3e-16 57.8 31.4 9.3e-16 57.8 21.8 3.3 2 1 0 2 2 2 1 Disintegrin Reprolysin PF01421.14 KFP00901.1 - 2.6e-07 30.4 0.3 2.6e-07 30.4 0.2 2.8 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease UPF0370 PF13980.1 KFP00901.1 - 0.0011 18.7 0.4 0.0025 17.5 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0370) Lipase PF00151.14 KFP00902.1 - 7.3e-108 360.6 0.0 8.8e-108 360.4 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 KFP00902.1 - 5.3e-18 65.4 1.8 9.6e-18 64.6 1.2 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 KFP00902.1 - 1.9e-05 24.6 0.1 2.4e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP00902.1 - 0.021 14.5 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family GSG-1 PF07803.6 KFP00902.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 GSG1-like protein MIP PF00230.15 KFP00903.1 - 4.5e-52 176.7 13.4 5.6e-52 176.4 9.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4401 PF14351.1 KFP00903.1 - 0.021 13.8 10.5 0.062 12.2 7.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) Aldedh PF00171.17 KFP00904.1 - 2.6e-182 606.3 0.0 2.9e-182 606.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFP00904.1 - 0.0073 15.0 0.1 0.096 11.3 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KFP00904.1 - 0.011 14.9 0.1 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ldh_2 PF02615.9 KFP00904.1 - 0.11 11.1 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase GCOM2 PF15328.1 KFP00905.1 - 2.8e-71 239.8 40.9 2.8e-71 239.8 28.3 2.0 2 0 0 2 2 2 1 Putative GRINL1B complex locus protein 2 BLOC1_2 PF10046.4 KFP00905.1 - 0.022 14.9 4.1 0.022 14.9 2.8 5.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HMA PF00403.21 KFP00905.1 - 0.063 13.4 2.4 0.25 11.5 0.0 3.1 3 0 0 3 3 3 0 Heavy-metal-associated domain DUF869 PF05911.6 KFP00905.1 - 0.27 9.4 55.9 0.45 8.6 37.3 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 KFP00905.1 - 0.56 9.3 14.3 0.36 9.9 3.3 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Amino_oxidase PF01593.19 KFP00905.1 - 0.56 9.2 3.0 0.57 9.1 1.2 1.6 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase DUF4195 PF13836.1 KFP00906.1 - 1.1e-22 80.6 12.4 1.1e-22 80.6 8.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4195) zf-H2C2_2 PF13465.1 KFP00906.1 - 0.0037 17.4 0.1 0.0037 17.4 0.1 10.3 11 2 1 12 12 12 3 Zinc-finger double domain zf-Di19 PF05605.7 KFP00906.1 - 0.008 16.2 1.9 0.008 16.2 1.3 7.5 6 2 1 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFP00906.1 - 0.011 15.9 0.7 0.011 15.9 0.5 8.4 9 1 0 9 9 9 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KFP00906.1 - 0.011 15.5 0.1 0.011 15.5 0.0 8.7 9 2 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFP00906.1 - 0.023 14.9 3.5 0.068 13.5 0.5 9.2 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP00906.1 - 0.038 14.1 0.2 0.038 14.1 0.1 7.3 6 1 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP00906.1 - 0.086 13.0 0.2 0.086 13.0 0.1 7.4 7 1 0 7 7 7 0 Zinc-finger of C2H2 type Trichoplein PF13868.1 KFP00907.1 - 2.7e-80 269.4 148.0 2.7e-80 269.4 102.6 2.0 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin RFX_DNA_binding PF02257.10 KFP00908.1 - 2.2e-33 114.2 0.0 1.1e-32 112.0 0.0 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFP00908.1 - 0.0001 22.4 0.1 0.00026 21.1 0.1 1.6 1 0 0 1 1 1 1 Poxvirus D5 protein-like Cdc6_C PF09079.6 KFP00908.1 - 0.037 13.7 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal HECT PF00632.20 KFP00909.1 - 1.8e-95 319.7 0.1 2.6e-95 319.2 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFP00909.1 - 2.8e-44 148.5 25.2 2.9e-13 49.4 0.4 5.4 5 0 0 5 5 5 4 WW domain C2 PF00168.25 KFP00909.1 - 9.4e-21 73.4 0.1 2.1e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 C2 domain fn3 PF00041.16 KFP00910.1 - 2.4e-63 210.2 4.8 2.8e-12 46.5 0.1 5.6 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 KFP00910.1 - 1.1e-56 188.6 0.0 3.2e-15 55.7 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP00910.1 - 1.1e-35 121.5 0.2 6.2e-08 32.6 0.0 5.1 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFP00910.1 - 3.7e-29 101.0 0.5 3.4e-07 30.6 0.0 6.2 6 0 0 6 6 6 4 Immunoglobulin domain ig PF00047.20 KFP00910.1 - 1.7e-24 85.6 0.0 0.00029 20.8 0.0 5.6 5 1 0 5 5 5 4 Immunoglobulin domain V-set PF07686.12 KFP00910.1 - 7.2e-19 67.7 0.1 0.00074 19.3 0.0 6.1 4 3 0 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP00910.1 - 4.2e-11 42.6 0.3 0.0085 15.9 0.0 4.6 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP00910.1 - 3e-07 29.0 0.1 0.044 12.0 0.0 3.5 2 1 1 3 3 3 3 Alphaherpesvirus glycoprotein E C1-set PF07654.10 KFP00910.1 - 0.00077 19.4 0.7 0.5 10.4 0.0 4.7 5 1 0 5 5 5 1 Immunoglobulin C1-set domain SusE PF14292.1 KFP00910.1 - 0.0023 17.7 0.6 1.3 8.8 0.0 4.4 5 0 0 5 5 5 1 SusE outer membrane protein Adeno_E3_CR2 PF02439.10 KFP00910.1 - 0.015 14.8 5.2 0.031 13.8 3.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycoprotein_G PF00802.14 KFP00910.1 - 0.05 12.7 0.7 0.093 11.8 0.5 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Syndecan PF01034.15 KFP00910.1 - 0.069 12.8 0.3 0.5 10.0 0.3 2.2 2 0 0 2 2 2 0 Syndecan domain PHD PF00628.24 KFP00911.1 - 5.8e-07 29.1 5.9 9.8e-07 28.3 4.1 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KFP00911.1 - 0.0069 16.0 2.8 0.0069 16.0 1.9 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 KFP00911.1 - 0.16 11.8 4.5 0.28 11.0 3.1 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 KFP00911.1 - 1.3 9.0 5.1 0.79 9.7 1.9 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain TPR_11 PF13414.1 KFP00912.1 - 3.1e-19 68.3 6.6 1.1e-13 50.5 2.4 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFP00912.1 - 1.6e-13 49.6 6.2 3.1e-06 26.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP00912.1 - 6.5e-12 44.4 5.3 0.00059 19.5 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFP00912.1 - 2e-08 33.9 0.3 0.0016 18.2 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP00912.1 - 2.5e-07 30.5 2.7 1.8e-06 27.7 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP00912.1 - 1.8e-05 24.1 3.6 2 8.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.11 KFP00912.1 - 0.0001 22.7 0.0 0.00033 21.1 0.0 1.9 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.1 KFP00912.1 - 0.0048 17.5 6.9 0.034 14.8 0.5 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFP00912.1 - 0.018 15.6 0.3 5.4 7.9 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFP00912.1 - 0.069 12.4 0.5 23 4.3 0.0 3.4 4 0 0 4 4 4 0 SHNi-TPR TACC PF05010.9 KFP00913.1 - 0.00028 20.7 6.1 0.00028 20.7 4.2 3.9 3 1 0 4 4 4 2 Transforming acidic coiled-coil-containing protein (TACC) Baculo_PEP_C PF04513.7 KFP00913.1 - 0.095 12.5 0.6 2.1 8.1 0.3 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KFP00913.1 - 0.71 9.6 24.2 0.17 11.6 3.4 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) JSRP PF15312.1 KFP00913.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.9 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Glyco_transf_22 PF03901.12 KFP00914.1 - 1e-109 367.3 28.9 1.3e-109 367.0 20.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2368 PF10166.4 KFP00914.1 - 6.9 6.2 6.6 3.2 7.3 0.4 2.7 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Ras PF00071.17 KFP00915.1 - 7.3e-58 194.5 0.0 8.7e-58 194.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP00915.1 - 1.7e-16 60.8 0.0 2.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP00915.1 - 7.1e-12 44.9 0.0 9.7e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP00915.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP00915.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP00915.1 - 0.02 14.0 0.0 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 KFP00915.1 - 0.038 13.6 0.2 4.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase FeoB_N PF02421.13 KFP00915.1 - 0.064 12.5 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 KFP00915.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 KFP00915.1 - 0.12 13.1 0.1 1.5 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain TPP_enzyme_M PF00205.17 KFP00915.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain AAA_24 PF13479.1 KFP00915.1 - 0.12 11.8 0.2 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATP-grasp_5 PF13549.1 KFP00915.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_L24e PF01246.15 KFP00916.1 - 1.1e-12 47.6 5.6 1.1e-12 47.6 3.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DDE_Tnp_1_4 PF13701.1 KFP00916.1 - 0.035 12.3 2.7 0.039 12.1 1.8 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Pkinase PF00069.20 KFP00917.1 - 6.9e-35 120.4 0.0 9.4e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.3 KFP00917.1 - 6.4e-31 106.7 5.0 1.3e-30 105.8 3.5 1.5 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.12 KFP00917.1 - 2.4e-14 53.0 0.0 3.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KFP00917.1 - 0.034 13.4 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PIP49_C PF12260.3 KFP00917.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 ASCH PF04266.9 KFP00918.1 - 5.6e-21 74.9 0.0 1.2e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.8 KFP00918.1 - 2.1e-17 62.6 9.6 2.1e-17 62.6 6.6 1.8 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type TraB PF01963.12 KFP00920.1 - 1.1e-10 41.4 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 TraB family Stap_Strp_tox_C PF02876.12 KFP00920.1 - 0.048 13.8 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain TraB PF01963.12 KFP00921.1 - 4.5e-08 32.8 0.0 3.6e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 TraB family SSF PF00474.12 KFP00922.1 - 8.4e-148 492.3 23.6 1.2e-147 491.8 16.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family SPATA6 PF14909.1 KFP00923.1 - 7.4e-52 175.1 0.0 2e-51 173.7 0.0 1.7 2 0 0 2 2 2 1 Spermatogenesis-assoc protein 6 BEN PF10523.4 KFP00924.1 - 3.8e-12 46.0 0.2 1e-11 44.7 0.1 1.8 1 1 0 1 1 1 1 BEN domain V_ATPase_I PF01496.14 KFP00924.1 - 0.24 9.2 2.5 0.34 8.7 1.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_1 PF00076.17 KFP00926.1 - 4.6e-66 218.3 0.1 5.1e-21 74.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP00926.1 - 9.4e-39 131.2 0.0 5.5e-14 51.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP00926.1 - 3.4e-29 100.4 0.2 3.1e-10 39.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP00926.1 - 0.00069 19.4 0.0 0.093 12.5 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFP00926.1 - 0.023 14.4 0.0 11 5.8 0.0 2.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 KFP00926.1 - 0.083 12.8 0.0 4.4 7.3 0.0 2.8 2 1 0 2 2 2 0 RNA binding domain RRM_2 PF04059.7 KFP00926.1 - 0.11 12.4 0.1 0.99 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif 2 UBX PF00789.15 KFP00927.1 - 4.8e-20 71.4 0.1 1.8e-19 69.5 0.1 2.0 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 KFP00927.1 - 4e-06 26.2 0.2 9.5e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.18 KFP00927.1 - 0.0015 17.9 0.0 0.26 10.6 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin family Ubiquitin_2 PF14560.1 KFP00927.1 - 0.0068 16.6 0.0 0.48 10.7 0.0 3.0 2 0 0 2 2 2 1 Ubiquitin-like domain AAA_11 PF13086.1 KFP00927.1 - 0.017 14.7 0.9 0.029 13.9 0.6 1.3 1 0 0 1 1 1 0 AAA domain BPL_N PF09825.4 KFP00927.1 - 0.19 10.4 1.3 0.29 9.8 0.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Borrelia_P83 PF05262.6 KFP00927.1 - 0.25 9.5 6.1 0.36 9.0 4.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.1 KFP00927.1 - 0.88 9.8 7.0 1.7 8.9 4.9 1.4 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KFP00928.1 - 1.5e-37 127.7 4.7 2.2e-17 63.1 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP00928.1 - 7.9e-26 89.5 5.3 8e-13 48.1 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFP00928.1 - 8.5e-21 72.6 2.1 1.2e-06 27.9 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFP00928.1 - 4.2e-20 71.7 1.9 2.3e-08 34.3 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP00928.1 - 4e-12 45.1 0.4 0.00012 21.9 0.0 4.1 5 0 0 5 5 5 3 Ankyrin repeat DUF1843 PF08898.5 KFP00928.1 - 0.0049 16.8 0.1 0.072 13.1 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1843) zf-RING_2 PF13639.1 KFP00929.1 - 5e-14 51.8 5.7 6.9e-14 51.4 4.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP00929.1 - 7.1e-09 35.5 6.2 1e-08 35.0 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP00929.1 - 1.2e-07 31.2 2.6 1.7e-07 30.7 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP00929.1 - 3e-06 26.7 3.5 4.7e-06 26.1 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP00929.1 - 3.6e-06 26.9 5.8 9.3e-06 25.6 4.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFP00929.1 - 3.7e-06 26.5 1.9 5.3e-06 26.0 1.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFP00929.1 - 0.017 14.8 1.4 0.031 14.0 0.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 KFP00929.1 - 0.027 14.2 1.1 0.041 13.6 0.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFP00929.1 - 0.068 13.0 3.9 0.13 12.1 2.7 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KFP00929.1 - 0.079 13.0 2.9 0.34 10.9 2.0 1.9 1 1 0 1 1 1 0 RING-variant domain BCDHK_Adom3 PF10436.4 KFP00929.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase FANCL_C PF11793.3 KFP00929.1 - 0.16 11.9 8.2 3.7 7.5 5.7 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 KFP00929.1 - 0.3 10.9 6.9 3.4 7.5 5.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KFP00929.1 - 0.39 10.4 3.6 0.43 10.3 0.4 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.3 KFP00929.1 - 0.49 9.9 2.9 0.78 9.3 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 KFP00929.1 - 0.6 9.8 4.1 1.4 8.6 2.8 1.7 1 1 0 1 1 1 0 PHD-finger DUF3808 PF10300.4 KFP00930.1 - 8.5e-144 479.5 13.9 2.1e-143 478.3 6.6 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 KFP00930.1 - 7.3e-10 39.2 4.9 2.3e-05 24.9 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP00930.1 - 1.8e-08 34.1 6.7 9.6e-08 31.8 1.4 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFP00930.1 - 5.8e-07 29.5 0.4 0.011 16.2 0.1 3.9 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP00930.1 - 1.6e-05 25.0 2.4 0.055 13.9 0.8 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFP00930.1 - 0.00035 20.2 13.2 0.015 15.1 1.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP00930.1 - 0.00036 20.7 8.3 0.038 14.3 1.4 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP00930.1 - 0.0017 17.8 9.5 0.27 10.9 1.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFP00930.1 - 0.0043 16.9 2.2 0.015 15.2 0.3 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP00930.1 - 0.0045 16.6 8.7 3.3 7.7 0.7 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFP00930.1 - 0.0076 16.5 0.0 0.45 11.0 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP00930.1 - 0.042 13.6 4.2 0.15 11.9 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFP00930.1 - 0.047 13.3 13.9 0.15 11.7 1.4 4.6 3 1 2 5 5 5 0 TPR repeat EF-hand_4 PF12763.2 KFP00931.1 - 1.7e-41 140.1 0.0 1.5e-23 82.5 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFP00931.1 - 4.3e-11 41.2 4.6 0.0027 16.8 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KFP00931.1 - 5.8e-11 42.3 0.4 0.021 14.9 0.0 4.8 4 1 1 5 5 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFP00931.1 - 6e-07 28.8 1.7 0.89 9.6 0.0 5.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 KFP00931.1 - 7.8e-06 25.4 6.4 0.039 13.5 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP00931.1 - 1.6e-05 24.0 2.9 0.6 9.5 0.1 3.8 3 0 0 3 3 3 2 EF hand IncA PF04156.9 KFP00931.1 - 0.00014 21.5 28.2 0.00014 21.5 19.5 2.9 2 1 1 3 3 3 2 IncA protein TMF_DNA_bd PF12329.3 KFP00931.1 - 0.00022 20.9 19.7 0.00022 20.9 13.7 4.8 3 1 4 7 7 5 3 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KFP00931.1 - 0.0016 17.6 15.6 0.011 14.9 3.4 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein LXG PF04740.7 KFP00931.1 - 0.016 14.9 23.3 0.07 12.9 4.1 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily Peptidase_C98 PF15499.1 KFP00931.1 - 0.18 11.0 6.0 0.29 10.3 4.2 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase AAA_13 PF13166.1 KFP00931.1 - 1.5 7.1 36.3 0.025 13.0 19.0 2.3 2 1 1 3 3 3 0 AAA domain Cluap1 PF10234.4 KFP00931.1 - 2.5 7.2 25.0 8.5 5.4 17.3 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 Atg14 PF10186.4 KFP00931.1 - 2.5 6.9 30.6 4 6.3 11.1 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IMD PF08397.6 KFP00931.1 - 3.2 7.0 21.8 11 5.2 9.5 2.3 1 1 1 2 2 2 0 IRSp53/MIM homology domain Laminin_II PF06009.7 KFP00931.1 - 3.3 7.4 19.5 4.3 7.0 1.2 2.8 1 1 1 2 2 2 0 Laminin Domain II DUF3584 PF12128.3 KFP00931.1 - 4.3 4.5 39.1 0.029 11.7 20.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Tweety PF04906.8 KFP00931.1 - 4.4 5.6 12.1 2.2 6.6 0.3 2.3 1 1 0 2 2 2 0 Tweety Fib_alpha PF08702.5 KFP00931.1 - 8.5 6.4 27.7 0.47 10.5 9.4 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Peptidase_M16 PF00675.15 KFP00932.1 - 2.5e-40 137.6 0.1 2.3e-39 134.4 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFP00932.1 - 7e-34 117.1 1.5 3.1e-19 69.3 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain TFIIF_alpha PF05793.7 KFP00932.1 - 5.2 5.3 19.1 8.8 4.5 13.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ras PF00071.17 KFP00933.1 - 4.3e-43 146.4 1.3 3.8e-38 130.4 0.5 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFP00933.1 - 7.6e-15 55.4 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP00933.1 - 6.3e-10 38.5 0.5 8.9e-10 38.0 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFP00933.1 - 1.5e-05 24.3 0.1 3.5e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFP00933.1 - 0.00021 20.5 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFP00933.1 - 0.018 13.7 0.5 2.1 6.9 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KFP00933.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.13 KFP00933.1 - 0.11 11.4 0.0 0.54 9.2 0.0 1.9 2 0 0 2 2 2 0 Septin Thioredoxin_7 PF13899.1 KFP00934.1 - 1.7e-17 63.1 0.0 2.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 KFP00934.1 - 1.5e-07 31.0 0.0 2.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFP00934.1 - 3e-05 24.1 0.1 0.00016 21.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.10 KFP00934.1 - 0.00068 19.3 0.1 0.0009 18.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.1 KFP00934.1 - 0.0012 18.9 0.0 0.0032 17.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KFP00934.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KFP00934.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family NAC PF01849.13 KFP00935.1 - 1e-22 79.3 0.1 1.8e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain RVT_1 PF00078.22 KFP00936.1 - 5.9e-13 48.6 0.0 1.5e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KFP00937.1 - 2.3e-14 53.2 0.0 3.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFP00937.1 - 0.096 12.2 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RRM_1 PF00076.17 KFP00940.1 - 0.0013 18.3 0.5 0.93 9.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_2 PF00891.13 KFP00941.1 - 6.8e-72 241.5 0.0 8.8e-72 241.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KFP00941.1 - 1.3e-08 35.3 0.0 2.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP00941.1 - 3.2e-07 30.1 0.0 5.1e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP00941.1 - 6e-06 26.5 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP00941.1 - 1.7e-05 25.2 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP00941.1 - 0.00037 20.1 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KFP00941.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_11 PF08241.7 KFP00941.1 - 0.0085 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP00941.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain adh_short PF00106.20 KFP00942.1 - 1.8e-11 44.2 0.0 1.2e-10 41.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFP00942.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Dimer_Tnp_hAT PF05699.9 KFP00943.1 - 2e-14 52.9 0.1 6.1e-14 51.4 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 KFP00943.1 - 4.4e-12 45.5 1.0 1e-11 44.4 0.7 1.6 1 0 0 1 1 1 1 BED zinc finger DUF4413 PF14372.1 KFP00943.1 - 0.00076 19.4 4.4 0.0012 18.7 0.4 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4413) CD99L2 PF12301.3 KFP00944.1 - 1.1e-16 60.9 4.2 1.3e-16 60.7 2.9 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 ENOD93 PF03386.9 KFP00944.1 - 0.035 13.8 0.5 0.038 13.7 0.3 1.1 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein Glycophorin_A PF01102.13 KFP00944.1 - 0.041 13.6 0.1 0.041 13.6 0.1 1.0 1 0 0 1 1 1 0 Glycophorin A DUF4199 PF13858.1 KFP00944.1 - 0.17 11.7 1.4 0.19 11.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2613 PF11021.3 KFP00944.1 - 0.54 10.0 2.8 0.63 9.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) CD99L2 PF12301.3 KFP00945.1 - 8.6e-20 71.0 0.0 1.4e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 CD99 antigen like protein 2 Glyco_transf_8 PF01501.15 KFP00946.1 - 7e-43 146.7 0.0 9.9e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 KFP00946.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 KFP00946.1 - 0.0024 17.2 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative TLV_coat PF00429.14 KFP00947.1 - 0.0076 14.7 0.2 0.0079 14.7 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) TipAS PF07739.8 KFP00947.1 - 0.029 14.6 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF3317 PF11779.3 KFP00948.1 - 4.4e-12 45.2 8.6 5.3e-12 44.9 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) NMD3 PF04981.8 KFP00949.1 - 1.9e-76 256.2 7.1 3.1e-76 255.5 4.9 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 KFP00949.1 - 0.037 13.8 7.7 0.16 11.8 4.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF1289 PF06945.8 KFP00949.1 - 0.07 12.6 1.7 2.8 7.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) TMEM37 PF15108.1 KFP00949.1 - 0.082 12.5 0.3 0.17 11.5 0.2 1.5 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family C1q PF00386.16 KFP00951.1 - 2.3e-34 118.1 0.0 2.7e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP00951.1 - 3e-14 52.3 47.9 1.2e-10 40.7 16.5 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TNF PF00229.13 KFP00951.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family TPR_11 PF13414.1 KFP00952.1 - 6.8e-22 76.9 9.9 4.3e-11 42.2 0.9 6.7 4 1 2 7 7 7 3 TPR repeat TPR_2 PF07719.12 KFP00952.1 - 2.7e-16 58.0 21.0 0.00053 19.6 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFP00952.1 - 2.2e-14 52.6 1.2 0.0032 17.9 0.0 7.9 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFP00952.1 - 2.4e-13 49.0 14.5 0.00082 18.8 0.0 7.7 7 1 2 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFP00952.1 - 4.4e-12 45.7 12.5 2.4e-05 24.1 0.2 7.1 4 1 3 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP00952.1 - 1.7e-10 41.2 0.3 2.9e-05 24.6 0.0 4.9 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP00952.1 - 7e-10 37.9 16.7 0.022 14.5 0.0 8.8 8 3 2 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP00952.1 - 4.1e-09 36.1 2.0 1.1e-05 25.1 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFP00952.1 - 7.2e-08 32.0 4.9 0.00012 21.9 0.0 5.5 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP00952.1 - 8.7e-06 25.9 8.2 0.0018 18.5 0.2 6.1 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP00952.1 - 2e-05 24.0 7.3 6.3 6.8 0.0 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP00952.1 - 0.00016 21.8 2.6 1.6 9.3 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP00952.1 - 0.00083 19.4 15.4 0.15 12.2 0.7 5.4 2 2 4 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 KFP00952.1 - 0.001 18.4 1.8 0.76 9.1 0.0 4.2 4 1 0 4 4 4 1 26S proteasome subunit RPN7 BTAD PF03704.12 KFP00952.1 - 0.0015 18.8 1.3 0.011 16.0 0.1 3.0 2 2 0 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 KFP00952.1 - 0.45 10.5 6.2 22 5.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3643 PF12356.3 KFP00953.1 - 9.7e-61 203.8 2.4 3.2e-60 202.1 1.7 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3643) UQ_con PF00179.21 KFP00953.1 - 3.7e-29 100.9 0.0 8.5e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BIR PF00653.16 KFP00953.1 - 2.4e-21 75.9 2.8 8e-21 74.2 1.9 2.0 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain UEV PF05743.8 KFP00953.1 - 4.9e-05 22.9 0.0 0.00013 21.5 0.0 1.7 1 0 0 1 1 1 1 UEV domain DUF3138 PF11336.3 KFP00953.1 - 1.5 6.9 8.2 2.6 6.1 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Yip1 PF04893.12 KFP00954.1 - 7.3e-10 38.6 21.9 1.8e-09 37.3 14.9 1.8 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KFP00954.1 - 3.6 7.2 14.9 5.3 6.6 10.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) BORG_CEP PF14957.1 KFP00955.1 - 1.3e-36 126.2 2.3 2.1e-36 125.5 1.6 1.3 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.23 KFP00955.1 - 3.8e-08 33.6 0.1 1.1e-07 32.1 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pneumo_phosprot PF02478.11 KFP00955.1 - 0.0031 17.0 0.6 0.004 16.7 0.4 1.1 1 0 0 1 1 1 1 Pneumovirus phosphoprotein TPR_11 PF13414.1 KFP00956.1 - 6.7e-08 32.0 1.0 9.4e-05 21.9 0.1 2.8 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KFP00956.1 - 1.1e-05 24.8 3.1 0.0032 17.0 0.5 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP00956.1 - 7.8e-05 22.1 2.3 0.013 15.2 0.4 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFP00956.1 - 0.00021 20.9 1.9 0.057 13.3 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFP00956.1 - 0.00086 19.3 0.1 2.2 8.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP00956.1 - 0.0011 19.3 0.0 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFP00956.1 - 0.032 14.1 0.0 0.18 11.7 0.0 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 KFP00956.1 - 0.038 14.1 1.9 0.064 13.3 0.2 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec16_C PF12931.2 KFP00956.1 - 0.06 13.0 0.3 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_6 PF13174.1 KFP00956.1 - 0.069 13.6 1.3 1.8 9.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFP00956.1 - 0.093 12.5 0.2 0.35 10.7 0.0 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Uds1 PF15456.1 KFP00956.1 - 0.61 10.0 6.6 3 7.8 4.6 2.0 1 1 0 1 1 1 0 Up-regulated During Septation RVT_1 PF00078.22 KFP00957.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HAD_2 PF13419.1 KFP00958.1 - 1e-23 84.4 0.0 1.3e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFP00958.1 - 1.3e-11 44.0 0.0 4.5e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KFP00958.1 - 1.3e-11 45.3 0.0 1.6e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KFP00958.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF4187 PF13821.1 KFP00959.1 - 1.1e-18 66.5 2.0 6e-18 64.1 1.4 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KFP00959.1 - 1.8e-15 56.4 1.2 4e-15 55.3 0.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFP00959.1 - 1.3e-06 28.1 4.8 1.3e-06 28.1 3.3 2.5 2 1 0 2 2 2 1 DExH-box splicing factor binding site DUF3889 PF13028.1 KFP00959.1 - 0.16 11.6 1.6 0.33 10.6 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) DUF1168 PF06658.7 KFP00959.1 - 8.1 5.9 23.2 0.45 10.0 5.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) HEAT_2 PF13646.1 KFP00960.1 - 1.2e-11 44.7 19.7 0.0012 19.1 0.4 8.0 5 2 1 6 6 6 4 HEAT repeats HEAT PF02985.17 KFP00960.1 - 2.4e-09 36.4 33.9 0.47 10.6 0.8 11.6 11 0 0 11 11 11 3 HEAT repeat HisKA_3 PF07730.8 KFP00960.1 - 0.082 13.2 2.5 0.75 10.1 0.1 3.5 3 0 0 3 3 3 0 Histidine kinase HEAT_EZ PF13513.1 KFP00960.1 - 9.3 6.8 34.1 32 5.1 0.3 9.7 10 1 1 11 11 11 0 HEAT-like repeat WD40 PF00400.27 KFP00961.1 - 1.1e-44 148.7 14.0 1.7e-09 37.2 0.1 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Striatin PF08232.7 KFP00961.1 - 4.3e-25 88.5 1.7 4.3e-25 88.5 1.2 2.2 2 0 0 2 2 2 1 Striatin family Nup160 PF11715.3 KFP00961.1 - 0.0077 14.4 0.1 1 7.4 0.0 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 VWA PF00092.23 KFP00962.1 - 4.6e-80 267.5 2.0 3.1e-43 147.5 0.6 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KFP00962.1 - 1.5e-27 96.7 0.0 7e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.14 KFP00962.1 - 1.3e-24 86.0 0.1 4.5e-24 84.2 0.0 1.9 1 0 0 1 1 1 1 LCCL domain VWA_3 PF13768.1 KFP00962.1 - 7.3e-08 32.2 0.0 0.0028 17.3 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFP00962.1 - 0.00022 21.1 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 vWA found in TerF C terminus VWA_CoxE PF05762.9 KFP00962.1 - 0.00023 20.3 0.0 0.018 14.1 0.0 2.5 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DUF1194 PF06707.6 KFP00962.1 - 0.00095 18.1 0.2 1.1 8.1 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1194) Mucin PF01456.12 KFP00962.1 - 0.013 15.2 15.7 0.022 14.5 10.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Rxt3 PF08642.5 KFP00962.1 - 0.093 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 7tm_1 PF00001.16 KFP00963.1 - 8.3e-30 103.7 11.7 9.3e-30 103.6 8.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FEZ PF07763.8 KFP00965.1 - 7.1e-95 317.3 15.0 9e-95 317.0 10.4 1.1 1 0 0 1 1 1 1 FEZ-like protein SCHIP-1 PF10148.4 KFP00965.1 - 0.0014 18.0 0.7 0.0022 17.4 0.5 1.3 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 EURL PF06937.6 KFP00965.1 - 0.036 13.4 7.1 0.04 13.3 4.2 1.6 1 1 0 1 1 1 0 EURL protein 1-cysPrx_C PF10417.4 KFP00965.1 - 0.07 12.8 0.0 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin PmbA_TldD PF01523.11 KFP00965.1 - 0.22 10.7 2.5 0.21 10.8 0.3 1.8 2 0 0 2 2 2 0 Putative modulator of DNA gyrase Topo-VIb_trans PF09239.6 KFP00965.1 - 1.2 8.6 4.4 0.57 9.6 0.4 2.1 1 1 1 2 2 2 0 Topoisomerase VI B subunit, transducer MRP-L46 PF11788.3 KFP00965.1 - 1.6 9.3 8.0 1 10.0 2.7 2.2 1 1 1 2 2 2 0 39S mitochondrial ribosomal protein L46 Transposase_24 PF03004.9 KFP00965.1 - 2.6 7.9 6.4 8.6 6.2 0.4 2.8 1 1 3 4 4 4 0 Plant transposase (Ptta/En/Spm family) NPV_P10 PF05531.7 KFP00965.1 - 2.9 8.2 9.1 9.5 6.5 0.6 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein VWC PF00093.13 KFP00966.1 - 5e-39 132.2 127.3 2.6e-11 43.4 10.1 16.2 10 2 5 15 15 15 6 von Willebrand factor type C domain Antistasin PF02822.9 KFP00966.1 - 3.9e-16 59.0 59.6 4.8e-07 29.9 6.3 16.6 19 2 0 19 19 19 4 Antistasin family TMEM154 PF15102.1 KFP00966.1 - 0.23 11.1 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family CBF PF03914.12 KFP00967.1 - 1.3e-50 171.0 0.3 1.3e-50 171.0 0.2 3.2 3 1 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.2 KFP00967.1 - 0.0013 18.5 2.1 0.043 13.6 1.3 2.5 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Methyltransf_28 PF02636.12 KFP00968.1 - 1.1e-73 247.7 0.0 1.8e-73 247.0 0.0 1.3 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF523 PF04463.7 KFP00968.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Pkinase PF00069.20 KFP00969.1 - 8.3e-64 215.2 0.0 1.4e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00969.1 - 2.8e-33 115.0 0.0 4.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFP00969.1 - 2.8e-26 90.9 19.1 2.7e-13 49.3 2.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFP00969.1 - 1.4e-09 38.0 0.3 4.3e-08 33.3 0.1 2.5 1 1 1 2 2 2 1 PH domain Kinase-like PF14531.1 KFP00969.1 - 3.1e-07 29.6 0.0 2.4e-05 23.4 0.0 2.8 2 1 0 3 3 3 1 Kinase-like Kdo PF06293.9 KFP00969.1 - 4.3e-05 22.6 0.0 8.6e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP00969.1 - 0.028 14.1 0.0 1.1 8.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFP00969.1 - 0.045 12.5 0.1 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-RING-like PF08746.6 KFP00969.1 - 0.081 12.9 16.6 0.91 9.5 3.6 2.8 2 0 0 2 2 2 0 RING-like domain RIO1 PF01163.17 KFP00969.1 - 0.11 11.8 0.2 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family PHD PF00628.24 KFP00969.1 - 0.11 12.2 16.8 1.1 8.9 3.7 2.6 2 0 0 2 2 2 0 PHD-finger C1_3 PF07649.7 KFP00969.1 - 0.15 12.1 13.3 0.86 9.6 0.9 2.7 2 0 0 2 2 2 0 C1-like domain FYVE_2 PF02318.11 KFP00969.1 - 0.46 10.4 11.1 2.1 8.2 4.0 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 KFP00969.1 - 0.71 9.6 16.3 0.25 11.0 1.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFP00969.1 - 1.6 8.0 8.9 1.1 8.5 0.4 2.8 2 0 0 2 2 2 0 PHD-finger Peptidase_M28 PF04389.12 KFP00970.1 - 1.7e-41 141.9 0.0 2.3e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Cation_efflux PF01545.16 KFP00971.1 - 4.1e-44 150.7 9.5 5.6e-44 150.3 6.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3112 PF11309.3 KFP00971.1 - 0.14 11.9 6.2 0.046 13.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) AAA PF00004.24 KFP00972.1 - 6.5e-40 136.3 0.0 1.9e-39 134.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 KFP00972.1 - 3.1e-11 42.9 1.4 4.4e-11 42.4 0.2 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 KFP00972.1 - 1.5e-06 27.4 0.1 7.2e-06 25.2 0.0 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFP00972.1 - 3e-06 27.4 0.2 0.00092 19.3 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFP00972.1 - 0.00015 21.4 0.2 0.0025 17.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFP00972.1 - 0.00038 19.2 0.1 0.001 17.8 0.0 1.6 1 1 1 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 KFP00972.1 - 0.00095 19.1 0.0 0.0034 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KFP00972.1 - 0.0012 19.6 0.0 0.003 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFP00972.1 - 0.0018 17.4 0.4 0.0063 15.7 0.3 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 KFP00972.1 - 0.0038 17.0 0.0 0.0093 15.8 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.12 KFP00972.1 - 0.0042 16.5 0.0 0.0096 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KFP00972.1 - 0.0057 16.5 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFP00972.1 - 0.0083 15.8 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFP00972.1 - 0.0093 15.9 0.8 0.074 13.0 0.2 2.9 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KFP00972.1 - 0.018 13.9 0.0 0.041 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 KFP00972.1 - 0.026 14.1 0.0 0.062 12.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_33 PF13671.1 KFP00972.1 - 0.026 14.4 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFP00972.1 - 0.073 12.4 0.3 0.67 9.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain DUF3549 PF12069.3 KFP00972.1 - 0.082 11.6 0.7 1.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3549) RNA_helicase PF00910.17 KFP00972.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Dpy-30 PF05186.8 KFP00973.1 - 3e-21 74.6 0.4 3e-21 74.6 0.3 1.5 2 0 0 2 2 2 1 Dpy-30 motif RIIa PF02197.12 KFP00973.1 - 0.0026 17.1 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Memo PF01875.12 KFP00974.1 - 3.3e-76 255.8 0.0 4e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Steroid_dh PF02544.11 KFP00975.1 - 1.1e-59 200.4 3.7 1.3e-59 200.2 2.6 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KFP00975.1 - 3.2e-06 26.6 0.1 3.9e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KFP00975.1 - 4.5e-05 23.4 0.7 9.7e-05 22.4 0.5 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase zf-DHHC PF01529.15 KFP00975.1 - 0.09 12.1 0.1 0.16 11.3 0.1 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase ELYS PF13934.1 KFP00976.1 - 4.6e-52 176.9 0.6 8.7e-52 176.0 0.4 1.5 1 0 0 1 1 1 1 Nuclear pore complex assembly Saccharop_dh PF03435.13 KFP00977.1 - 2.3e-43 148.6 0.0 2.7e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Consortin_C PF15281.1 KFP00978.1 - 3.2e-56 187.8 0.7 6.9e-56 186.7 0.0 2.0 2 0 0 2 2 2 1 Consortin C-terminus TPR_7 PF13176.1 KFP00978.1 - 0.0095 15.6 0.4 0.095 12.5 0.2 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat RrnaAD PF00398.15 KFP00979.1 - 8.5e-15 54.4 0.0 1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase SET PF00856.23 KFP00980.1 - 2.6e-12 47.3 0.5 5.8e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.1 KFP00980.1 - 2.2e-05 24.3 0.1 4.6e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Kinesin PF00225.18 KFP00981.1 - 1.5e-61 207.9 0.0 2.4e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain SPRY PF00622.23 KFP00982.1 - 6.2e-25 87.6 0.3 6.2e-25 87.6 0.2 2.3 3 0 0 3 3 3 1 SPRY domain AAA_33 PF13671.1 KFP00982.1 - 6.7e-23 81.1 0.1 1.5e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFP00982.1 - 4.5e-05 22.6 0.2 8.8e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 KFP00982.1 - 0.013 16.3 0.0 0.047 14.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFP00982.1 - 0.018 14.4 0.3 0.031 13.7 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3767 PF12597.3 KFP00983.1 - 6e-15 54.9 0.1 7.3e-15 54.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Vitelline_membr PF10542.4 KFP00983.1 - 0.019 14.6 0.1 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region Peptidase_C97 PF05903.9 KFP00984.1 - 2.2e-39 134.6 0.0 2.9e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain YxiJ PF14176.1 KFP00984.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 YxiJ-like protein RNase_H2-Ydr279 PF09468.5 KFP00984.1 - 0.048 12.8 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LRAT PF04970.8 KFP00984.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Adenylsucc_synt PF00709.16 KFP00985.1 - 2.8e-145 484.2 0.0 3.1e-145 484.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Spore_YpjB PF09577.5 KFP00985.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) BTB PF00651.26 KFP00986.1 - 2.9e-27 94.8 1.2 5.2e-27 94.0 0.8 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP00986.1 - 8.2e-18 63.7 23.0 3.6e-08 33.2 1.4 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFP00986.1 - 5.5e-13 48.4 35.0 0.0015 18.7 1.6 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP00986.1 - 5.3e-12 45.1 29.4 0.0053 16.9 1.9 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP00986.1 - 0.00013 22.0 17.2 0.011 15.9 0.0 5.0 4 1 1 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP00986.1 - 0.0016 18.5 0.1 0.0016 18.5 0.1 5.1 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP00986.1 - 0.011 15.6 22.8 0.099 12.5 0.8 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger GAGA PF09237.6 KFP00986.1 - 0.018 14.5 6.3 0.45 10.1 0.2 3.5 2 1 1 3 3 3 0 GAGA factor zinc_ribbon_5 PF13719.1 KFP00986.1 - 0.23 11.0 3.5 44 3.7 0.0 3.8 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.1 KFP00986.1 - 0.62 10.0 6.6 2.6 8.0 0.5 2.8 2 0 0 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.1 KFP00986.1 - 0.9 9.2 5.0 36 4.1 0.0 3.8 3 0 0 3 3 3 0 zinc-ribbon domain RRN7 PF11781.3 KFP00986.1 - 3.3 7.3 6.3 5.5 6.5 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Pkinase PF00069.20 KFP00987.1 - 9.6e-76 254.3 0.1 3.1e-75 252.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP00987.1 - 1.2e-36 126.1 0.0 1.6e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP00987.1 - 5.3e-08 32.1 0.0 1.3e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 KFP00987.1 - 6.7e-08 32.6 0.2 2.8e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.19 KFP00987.1 - 3.7e-07 30.5 2.3 7.2e-07 29.6 1.6 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.1 KFP00987.1 - 0.14 12.4 1.0 3.2 8.0 0.7 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain CEP170_C PF15308.1 KFP00988.1 - 1.5e-250 833.2 62.0 1.5e-250 833.2 43.0 4.2 4 1 0 4 4 4 1 CEP170 C-terminus FHA PF00498.21 KFP00988.1 - 1.4e-14 53.9 0.1 6.7e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 FHA domain PLDc_3 PF13918.1 KFP00989.1 - 3.6e-67 225.2 0.2 3.6e-67 225.2 0.1 1.5 2 0 0 2 2 2 1 PLD-like domain PLDc_2 PF13091.1 KFP00989.1 - 1.2e-12 47.7 0.1 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFP00989.1 - 5.6e-09 35.5 0.9 8.9e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF1669 PF07894.7 KFP00989.1 - 0.037 13.2 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Atg8 PF02991.11 KFP00990.1 - 3.2e-39 133.0 0.3 3.6e-39 132.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFP00990.1 - 4.8e-06 26.6 0.1 5.9e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 XPG_I PF00867.13 KFP00991.1 - 8.5e-27 93.0 0.1 2.5e-26 91.5 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFP00991.1 - 1.4e-22 79.8 0.0 3e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KFP00991.1 - 9.2e-05 22.0 0.1 0.00019 21.0 0.1 1.5 1 0 0 1 1 1 1 XPG domain containing WD40 PF00400.27 KFP00992.1 - 6.3e-08 32.2 0.4 0.0016 18.2 0.1 2.8 2 1 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFP00992.1 - 0.0087 14.8 0.0 0.26 9.9 0.0 2.1 1 1 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 KFP00993.1 - 0.28 11.1 2.5 12 5.9 0.2 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat 7tm_1 PF00001.16 KFP00994.1 - 3.1e-27 95.3 13.5 3.6e-27 95.1 9.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Herpes_UL49_5 PF05702.6 KFP00994.1 - 0.039 13.8 0.9 2.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Imm20 PF15568.1 KFP00994.1 - 0.076 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 20 IRK PF01007.15 KFP00994.1 - 0.73 8.5 7.4 4.2 6.0 0.1 2.1 2 0 0 2 2 2 0 Inward rectifier potassium channel Pex24p PF06398.6 KFP00994.1 - 1.5 7.5 7.3 6 5.5 2.2 2.1 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Mannosyl_trans PF05007.8 KFP00995.1 - 3e-98 328.6 21.7 3.7e-98 328.3 15.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KFP00995.1 - 7.6e-10 38.1 16.6 7.6e-10 38.1 11.5 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U RGS PF00615.14 KFP00996.1 - 4.5e-35 120.2 1.6 1.3e-34 118.8 0.0 2.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 KFP00996.1 - 7.4e-17 60.8 0.0 3.4e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 KFP00996.1 - 1.9e-15 56.3 0.1 6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 GGL domain RGS-like PF09128.6 KFP00996.1 - 0.047 13.1 0.3 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain DAN PF03045.10 KFP00997.1 - 1e-40 137.9 11.4 1.3e-40 137.6 7.9 1.1 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 KFP00997.1 - 6.4e-05 22.9 8.0 9.4e-05 22.4 5.5 1.2 1 0 0 1 1 1 1 Cystine-knot domain TIR_2 PF13676.1 KFP00997.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 TIR domain FH2 PF02181.18 KFP00998.1 - 0.0046 15.8 0.3 0.0046 15.8 0.2 1.4 2 0 0 2 2 2 1 Formin Homology 2 Domain CAT PF00302.13 KFP00998.1 - 0.12 12.0 0.2 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase FH2 PF02181.18 KFP00999.1 - 4.9e-84 282.3 8.0 7.7e-84 281.6 5.6 1.3 1 1 0 1 1 1 1 Formin Homology 2 Domain Drf_FH1 PF06346.7 KFP00999.1 - 0.0056 16.2 58.8 0.0056 16.2 40.7 2.0 1 1 1 2 2 2 1 Formin Homology Region 1 Corona_S2 PF01601.11 KFP00999.1 - 0.061 11.4 0.2 0.095 10.7 0.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein tRNA-synt_His PF13393.1 KFP00999.1 - 0.29 10.1 1.5 0.57 9.1 1.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase 7tm_1 PF00001.16 KFP01000.1 - 4.2e-87 291.5 5.4 7.9e-87 290.6 3.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP01000.1 - 2.1e-08 33.6 5.7 2.1e-08 33.6 3.9 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP01000.1 - 3e-07 29.8 6.3 3e-07 29.8 4.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PgaD PF13994.1 KFP01000.1 - 0.47 9.9 7.3 1 8.8 0.2 2.8 2 0 0 2 2 2 0 PgaD-like protein Phosphodiest PF01663.17 KFP01001.1 - 6.1e-79 265.9 0.0 8.8e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Endonuclease_NS PF01223.18 KFP01001.1 - 2.4e-09 37.1 0.1 4.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Sulfatase PF00884.18 KFP01001.1 - 4.5e-05 22.7 0.0 0.0031 16.7 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KFP01001.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Cys_knot PF00007.17 KFP01002.1 - 2e-16 59.9 9.9 2e-16 59.9 6.8 2.9 3 1 0 3 3 3 1 Cystine-knot domain TSP_1 PF00090.14 KFP01002.1 - 7.1e-11 42.0 6.4 7.1e-11 42.0 4.4 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain VWC PF00093.13 KFP01002.1 - 2.6e-10 40.2 9.4 2.6e-10 40.2 6.5 3.8 2 1 0 2 2 2 1 von Willebrand factor type C domain Cu2_monooxygen PF01082.15 KFP01003.1 - 6e-45 152.4 0.9 9e-45 151.8 0.2 1.7 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.10 KFP01003.1 - 9.4e-36 122.5 0.1 6.5e-35 119.8 0.0 2.2 3 0 0 3 3 3 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.12 KFP01003.1 - 8.9e-12 45.0 0.2 1.5e-11 44.2 0.2 1.4 1 0 0 1 1 1 1 DOMON domain Syntaxin_2 PF14523.1 KFP01004.1 - 4.5e-27 94.0 14.4 4.8e-27 93.9 5.9 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KFP01004.1 - 6.4e-20 70.5 6.9 6.4e-20 70.5 4.8 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFP01004.1 - 8e-09 35.5 1.1 8e-09 35.5 0.8 2.4 2 1 0 2 2 2 1 Syntaxin Sec5 PF15469.1 KFP01004.1 - 0.17 11.6 3.2 0.57 9.8 0.1 2.3 2 1 0 2 2 2 0 Exocyst complex component Sec5 MCPsignal PF00015.16 KFP01004.1 - 0.17 11.4 8.3 0.36 10.3 1.4 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain EAP30 PF04157.11 KFP01004.1 - 0.61 9.2 5.6 0.14 11.2 1.0 2.2 2 1 0 2 2 2 0 EAP30/Vps36 family Spectrin PF00435.16 KFP01004.1 - 0.82 9.9 15.0 2.1 8.6 3.7 3.2 2 2 0 2 2 2 0 Spectrin repeat GAS PF13851.1 KFP01004.1 - 0.84 8.7 14.5 4.2 6.5 4.7 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cob_adeno_trans PF01923.13 KFP01004.1 - 0.85 9.3 6.1 0.89 9.3 0.8 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF2383 PF09537.5 KFP01004.1 - 0.86 9.8 6.4 7.3 6.8 0.2 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF2383) 4HB_MCP_1 PF12729.2 KFP01004.1 - 3.1 7.1 10.9 0.42 9.9 2.1 2.6 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF1759 PF03564.10 KFP01004.1 - 4.6 7.0 6.8 4.9 6.9 0.3 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1759) APG6 PF04111.7 KFP01004.1 - 8.5 5.3 14.6 0.24 10.4 3.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 7tm_1 PF00001.16 KFP01005.1 - 1.5e-56 191.3 17.7 2.1e-56 190.9 12.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 KFP01006.1 - 2.3e-62 210.4 17.9 3.4e-62 209.9 12.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP01006.1 - 4.8e-05 22.6 27.8 6.8e-05 22.1 19.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF4231 PF14015.1 KFP01006.1 - 0.039 13.9 3.3 0.6 10.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) NfeD PF01957.13 KFP01006.1 - 5.3 7.1 10.0 1.5 8.9 0.9 3.0 1 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding CN_hydrolase PF00795.17 KFP01007.1 - 5.7e-16 58.4 0.0 8.5e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sec10 PF07393.6 KFP01007.1 - 0.2 9.8 0.0 0.26 9.4 0.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 CN_hydrolase PF00795.17 KFP01008.1 - 0.00032 20.0 0.1 0.099 11.9 0.0 2.3 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase MFS_1 PF07690.11 KFP01009.1 - 1.8e-38 132.1 69.3 7.6e-24 84.0 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFP01009.1 - 1.1e-06 27.4 9.1 1.1e-06 27.4 6.3 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein LacY_symp PF01306.14 KFP01009.1 - 0.026 13.0 19.8 0.042 12.3 0.6 2.5 1 1 1 2 2 2 0 LacY proton/sugar symporter Ribosomal_L7Ae PF01248.21 KFP01010.1 - 8.8e-31 105.2 1.9 1.1e-30 105.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HLH PF00010.21 KFP01012.1 - 1.2e-16 60.0 0.2 1.9e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TBP PF00352.16 KFP01013.1 - 5.9e-47 156.9 0.2 3.1e-23 80.9 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFP01013.1 - 2.5e-05 24.2 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Sugar_tr PF00083.19 KFP01014.1 - 1.7e-98 330.1 29.7 4.5e-75 252.9 11.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFP01014.1 - 4.4e-30 104.6 34.8 4.6e-26 91.3 15.5 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KFP01016.1 - 8.7e-171 568.2 0.0 1e-170 568.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFP01016.1 - 0.11 11.7 0.0 0.85 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GTP_EFTU PF00009.22 KFP01017.1 - 3.6e-49 166.7 0.0 7.5e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KFP01017.1 - 1.5e-23 82.7 4.8 3.3e-23 81.5 3.4 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 KFP01017.1 - 4.2e-21 74.9 1.0 1e-20 73.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFP01017.1 - 6.5e-08 32.5 0.0 2.1e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFP01017.1 - 6.3e-07 29.3 0.1 3e-06 27.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFP01017.1 - 0.00013 22.4 1.1 0.0058 17.1 0.1 3.0 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 KFP01017.1 - 0.00062 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA_22 PF13401.1 KFP01017.1 - 0.027 14.6 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KFP01017.1 - 0.039 13.1 0.4 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFP01017.1 - 0.12 11.9 0.5 0.38 10.3 0.0 2.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain Cmyb_C PF09316.5 KFP01018.1 - 7.4e-70 233.9 4.1 1.6e-69 232.8 2.8 1.6 1 0 0 1 1 1 1 C-myb, C-terminal Myb_DNA-binding PF00249.26 KFP01018.1 - 7.3e-52 173.2 19.0 4.2e-17 61.9 1.3 4.2 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFP01018.1 - 2e-42 143.1 19.6 3.4e-19 68.6 1.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain LMSTEN PF07988.7 KFP01018.1 - 3e-29 100.0 0.6 5.9e-29 99.1 0.4 1.5 1 0 0 1 1 1 1 LMSTEN motif Rap1_C PF11626.3 KFP01018.1 - 0.075 12.9 9.1 15 5.5 3.0 3.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.5 KFP01018.1 - 0.11 12.1 0.0 0.78 9.4 0.0 2.4 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.1 KFP01018.1 - 9 6.5 16.9 3.9 7.6 1.1 3.9 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain PDEase_I PF00233.14 KFP01019.1 - 2.2e-62 210.9 0.5 2.9e-62 210.5 0.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SNARE PF05739.14 KFP01019.1 - 0.11 12.2 0.7 0.23 11.1 0.5 1.6 1 0 0 1 1 1 0 SNARE domain THRAP3_BCLAF1 PF15440.1 KFP01020.1 - 1.4e-179 598.9 108.3 1.4e-179 598.9 75.1 2.5 3 0 0 3 3 3 1 THRAP3/BCLAF1 family GRP PF07172.6 KFP01020.1 - 1.2 9.6 16.7 0.029 14.8 3.6 3.7 2 1 0 2 2 2 0 Glycine rich protein family Mo25 PF08569.6 KFP01021.1 - 0.042 12.8 0.4 0.048 12.6 0.2 1.1 1 0 0 1 1 1 0 Mo25-like MAP7 PF05672.6 KFP01022.1 - 3e-55 186.1 77.7 3e-55 186.1 53.9 3.6 4 0 0 4 4 4 1 MAP7 (E-MAP-115) family WD40 PF00400.27 KFP01023.1 - 4.9e-43 143.5 11.2 7.4e-10 38.3 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KFP01023.1 - 0.00018 21.2 0.1 0.0021 17.7 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFP01023.1 - 0.062 11.4 2.6 9.6 4.2 0.3 3.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Rav1p_C PF12234.3 KFP01023.1 - 0.18 9.9 0.1 0.24 9.5 0.1 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal TPT PF03151.11 KFP01024.1 - 1.6e-07 31.1 13.7 2e-07 30.7 9.5 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family Potyvirid-P3 PF13608.1 KFP01024.1 - 0.026 13.6 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF4199 PF13858.1 KFP01024.1 - 0.026 14.4 0.6 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) VIT1 PF01988.14 KFP01024.1 - 0.22 10.9 4.4 0.06 12.8 0.7 1.8 1 1 1 2 2 2 0 VIT family 7TMR-DISM_7TM PF07695.6 KFP01024.1 - 2.7 7.6 9.8 2.9 7.5 5.2 1.7 1 1 1 2 2 2 0 7TM diverse intracellular signalling Tissue_fac PF01108.12 KFP01025.1 - 1.7e-26 92.0 0.1 4.6e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 KFP01025.1 - 2.5e-21 75.6 0.8 1.1e-20 73.5 0.1 2.3 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFP01026.1 - 8.2e-31 105.9 0.3 1.1e-30 105.4 0.2 1.2 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 KFP01026.1 - 1.5e-17 63.5 0.1 3.9e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFP01027.1 - 3.8e-19 68.4 0.2 4.2e-19 68.2 0.1 1.0 1 0 0 1 1 1 1 Tissue factor HLH PF00010.21 KFP01028.1 - 2.2e-12 46.4 0.2 3.9e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLAIN PF15301.1 KFP01028.1 - 0.14 11.3 3.1 0.15 11.1 2.1 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family zf-A20 PF01754.11 KFP01029.1 - 1.7e-40 136.1 78.2 5.5e-11 41.8 2.7 7.8 7 0 0 7 7 7 7 A20-like zinc finger OTU PF02338.14 KFP01029.1 - 2e-27 96.2 0.0 5.6e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease PMP22_Claudin PF00822.15 KFP01030.1 - 1.3e-07 31.3 9.6 1.7e-07 31.0 6.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 KFP01030.1 - 0.00049 20.1 7.2 0.0012 18.9 5.0 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 KFP01030.1 - 0.00065 19.4 10.7 0.0012 18.6 7.3 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PalH PF08733.5 KFP01030.1 - 0.024 13.4 4.0 0.035 12.9 2.8 1.1 1 0 0 1 1 1 0 PalH/RIM21 zf-LITAF-like PF10601.4 KFP01030.1 - 0.8 9.6 5.7 12 5.8 0.6 2.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Pox_A14 PF05767.7 KFP01030.1 - 4.9 7.1 9.0 0.38 10.7 2.8 1.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 PMP22_Claudin PF00822.15 KFP01031.1 - 7e-11 42.0 3.6 1e-10 41.5 2.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP01031.1 - 9.2e-06 25.4 8.8 1.7e-05 24.5 6.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KFP01031.1 - 0.00073 19.5 5.9 0.0019 18.2 4.1 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PalH PF08733.5 KFP01031.1 - 0.015 14.1 3.5 0.02 13.7 2.4 1.1 1 0 0 1 1 1 0 PalH/RIM21 Pox_A14 PF05767.7 KFP01031.1 - 1.8 8.5 9.4 1.5 8.8 4.0 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF1981 PF09324.5 KFP01032.1 - 4.5e-09 35.6 5.6 4.8e-07 29.2 1.1 4.5 3 1 0 3 3 3 1 Domain of unknown function (DUF1981) DUF4061 PF13270.1 KFP01034.1 - 2.1e-33 114.2 2.4 2.9e-33 113.8 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) Golgin_A5 PF09787.4 KFP01034.1 - 0.014 13.9 1.8 0.019 13.5 1.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Costars PF14705.1 KFP01035.1 - 1.2e-32 111.6 0.4 1.3e-32 111.5 0.3 1.0 1 0 0 1 1 1 1 Costars HECA PF15353.1 KFP01036.1 - 3.6e-39 132.7 8.4 7.5e-39 131.7 5.8 1.6 1 0 0 1 1 1 1 Headcase protein family homologue RecR PF02132.10 KFP01036.1 - 0.045 13.1 3.2 1.7 8.1 0.1 2.9 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.1 KFP01036.1 - 0.31 10.3 5.9 6.3 6.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFP01036.1 - 2.5 7.7 10.8 2.7 7.5 0.5 3.5 3 0 0 3 3 3 0 zinc-ribbon domain CITED PF04487.7 KFP01037.1 - 1.6e-86 289.9 10.8 1.9e-86 289.6 7.5 1.1 1 0 0 1 1 1 1 CITED 7tm_1 PF00001.16 KFP01039.1 - 3.4e-54 183.6 15.0 4.3e-54 183.3 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP01039.1 - 1.5e-10 40.7 9.5 1.9e-10 40.3 6.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFP01039.1 - 4.4e-08 32.5 14.2 6.2e-08 32.1 9.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP01039.1 - 0.0023 17.1 9.5 0.0023 17.1 6.6 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.4 KFP01039.1 - 0.048 12.7 15.3 0.1 11.7 10.6 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Ribosomal_L24e PF01246.15 KFP01039.1 - 0.059 13.2 0.1 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L24e PLAC8 PF04749.12 KFP01039.1 - 0.2 12.2 1.6 0.73 10.4 0.0 2.5 1 1 1 2 2 2 0 PLAC8 family Connexin_CCC PF10582.4 KFP01040.1 - 2.8e-20 71.8 4.6 7.7e-20 70.4 3.2 1.8 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin PF00029.14 KFP01040.1 - 1.4e-10 41.1 0.1 1.4e-10 41.1 0.0 2.5 2 1 1 3 3 3 1 Connexin DUF4051 PF13260.1 KFP01040.1 - 0.3 10.4 0.1 0.3 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF605 PF04652.11 KFP01041.1 - 1.6e-83 281.2 9.9 1.2e-60 205.9 0.1 2.0 1 1 1 2 2 2 2 Vta1 like DAG_kinase_N PF14513.1 KFP01041.1 - 0.097 12.8 0.3 0.38 10.9 0.0 2.1 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus 7tm_2 PF00002.19 KFP01042.1 - 2.6e-49 167.5 16.5 2.6e-49 167.5 11.4 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) CUB PF00431.15 KFP01042.1 - 2.6e-24 85.4 0.0 6.4e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 CUB domain GPS PF01825.16 KFP01042.1 - 3e-17 62.4 1.1 1e-16 60.7 0.7 2.0 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Pentaxin PF00354.12 KFP01042.1 - 1.1e-09 37.9 0.6 3.8e-09 36.2 0.2 2.1 2 0 0 2 2 2 1 Pentaxin family Laminin_G_3 PF13385.1 KFP01042.1 - 0.00044 20.5 0.1 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily zf-C2H2 PF00096.21 KFP01043.1 - 1.6e-17 62.6 28.7 0.00018 21.6 1.1 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP01043.1 - 2.2e-12 46.6 37.4 5.2e-07 29.6 0.7 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP01043.1 - 3.8e-12 45.9 22.6 0.00064 19.7 0.8 5.1 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFP01043.1 - 3.4e-08 33.2 23.9 0.02 15.2 0.3 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFP01043.1 - 4.3e-05 23.5 25.4 0.007 16.5 1.8 5.2 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFP01043.1 - 0.62 10.1 18.9 0.082 13.0 2.1 4.0 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Far-17a_AIG1 PF04750.9 KFP01044.1 - 2e-72 242.5 12.0 2.4e-72 242.3 8.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein dCMP_cyt_deam_1 PF00383.17 KFP01046.1 - 7.2e-17 60.9 0.6 9.9e-17 60.4 0.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KFP01046.1 - 0.00012 21.7 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 KFP01046.1 - 0.00084 19.2 3.8 0.017 15.0 2.6 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase Peroxin-3 PF04882.7 KFP01047.1 - 1.2e-101 340.5 3.6 2.9e-79 266.7 0.1 2.0 1 1 1 2 2 2 2 Peroxin-3 DUF3631 PF12307.3 KFP01047.1 - 0.045 13.6 0.1 0.2 11.5 0.0 2.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3631) Alpha_L_fucos PF01120.12 KFP01048.1 - 1e-121 406.0 3.9 1.2e-121 405.8 2.7 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase RPEL PF02755.10 KFP01049.1 - 2e-28 96.8 29.0 1.1e-09 37.3 0.4 4.7 5 0 0 5 5 5 4 RPEL repeat PBP1_TM PF14812.1 KFP01049.1 - 1.3 9.4 14.4 0.074 13.3 3.1 3.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LTV PF04180.9 KFP01050.1 - 1.9e-102 343.9 18.6 2.5e-102 343.5 12.9 1.2 1 0 0 1 1 1 1 Low temperature viability protein Sec62 PF03839.11 KFP01050.1 - 5.6 6.3 9.8 15 4.9 6.8 1.8 1 0 0 1 1 1 0 Translocation protein Sec62 zf-H2C2_2 PF13465.1 KFP01051.1 - 4.9e-19 67.6 60.5 8.6e-05 22.6 3.0 8.7 8 0 0 8 8 8 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFP01051.1 - 6e-17 60.8 61.3 0.0014 18.8 5.2 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP01051.1 - 5e-15 54.6 50.3 0.0011 19.0 3.2 7.6 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP01051.1 - 1.7e-05 24.5 32.8 0.0042 16.9 0.1 6.7 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP01051.1 - 5.4e-05 23.2 31.2 0.11 12.7 2.4 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP01051.1 - 0.014 15.4 34.5 2.8 8.1 8.9 4.7 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Viral_protease PF08715.5 KFP01051.1 - 0.093 11.7 2.4 0.085 11.9 0.2 1.8 1 1 1 2 2 2 0 Papain like viral protease zf-met PF12874.2 KFP01051.1 - 0.18 12.0 27.3 1.5 9.0 0.1 6.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type PyrI_C PF02748.10 KFP01051.1 - 7.6 6.0 19.6 0.57 9.6 0.4 4.7 3 2 2 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ADK_lid PF05191.9 KFP01051.1 - 9.9 5.9 16.5 0.63 9.7 0.2 3.8 4 1 0 4 4 4 0 Adenylate kinase, active site lid SET PF00856.23 KFP01052.1 - 0.0015 18.8 0.1 1.9 8.7 0.0 2.2 1 1 1 2 2 2 2 SET domain zf-C2H2 PF00096.21 KFP01052.1 - 0.096 13.0 7.9 0.18 12.2 0.4 3.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP01052.1 - 0.59 10.5 7.2 0.18 12.2 1.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP01052.1 - 8.7 6.4 7.1 0.64 10.0 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Radial_spoke_3 PF06098.6 KFP01053.1 - 5.6e-118 393.1 14.5 7e-118 392.8 10.1 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 DUF2866 PF11065.3 KFP01053.1 - 0.14 12.0 1.9 1.6 8.6 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) RhoGAP PF00620.22 KFP01054.1 - 1.5e-40 138.2 0.5 2.9e-40 137.3 0.4 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF2183 PF09949.4 KFP01054.1 - 0.015 15.1 0.2 0.05 13.5 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) HCaRG PF07258.9 KFP01055.1 - 8.2e-41 139.4 0.9 9.1e-41 139.3 0.6 1.0 1 0 0 1 1 1 1 HCaRG protein Neil1-DNA_bind PF09292.5 KFP01056.1 - 6.9e-27 92.9 0.4 1.4e-26 92.0 0.3 1.5 1 0 0 1 1 1 1 Endonuclease VIII-like 1, DNA bind H2TH PF06831.9 KFP01056.1 - 2.7e-11 43.0 0.0 4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Glyco_hydro_38 PF01074.17 KFP01057.1 - 2.3e-89 299.3 0.1 4.1e-89 298.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFP01057.1 - 3.1e-69 233.9 0.0 7.2e-69 232.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFP01057.1 - 2.2e-29 101.4 0.1 1.7e-27 95.3 0.0 2.4 2 0 0 2 2 2 1 Alpha mannosidase, middle domain MHCassoc_trimer PF08831.5 KFP01057.1 - 0.11 12.3 1.6 0.35 10.7 1.1 1.8 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain PAH PF02671.16 KFP01058.1 - 4.8e-55 182.9 2.5 1.5e-20 72.5 0.1 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KFP01058.1 - 2.6e-43 145.9 0.3 7.6e-43 144.3 0.2 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Y_phosphatase PF00102.22 KFP01059.1 - 1.8e-81 272.9 0.0 2.7e-81 272.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CRAL_TRIO PF00650.15 KFP01059.1 - 1.2e-30 106.0 0.1 2.8e-30 104.8 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFP01059.1 - 2.9e-11 43.4 0.3 7.4e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFP01059.1 - 1.7e-05 24.8 0.1 0.00034 20.7 0.0 2.6 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DSPc PF00782.15 KFP01059.1 - 0.0028 17.2 0.5 0.011 15.2 0.1 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP01059.1 - 0.0035 17.5 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP01059.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate BAR_3_WASP_bdg PF10456.4 KFP01061.1 - 5.6e-109 362.9 4.2 7.3e-109 362.5 2.9 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 KFP01061.1 - 3.9e-20 71.7 2.9 8.4e-20 70.6 0.9 2.2 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.1 KFP01061.1 - 1e-11 44.2 0.0 2.6e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP01061.1 - 4e-10 38.9 0.0 1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP01061.1 - 2.7e-09 36.3 0.0 8.7e-09 34.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 KFP01061.1 - 0.00044 19.5 2.2 0.033 13.4 0.5 2.8 1 1 1 2 2 2 2 Vps5 C terminal like XFP PF03894.10 KFP01061.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DUF3295 PF11702.3 KFP01061.1 - 0.22 10.4 2.9 2.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) LRR_8 PF13855.1 KFP01063.1 - 4.3e-51 170.5 54.1 1.4e-12 47.1 2.3 6.3 2 1 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.1 KFP01063.1 - 2.7e-27 95.0 0.5 1e-11 44.6 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFP01063.1 - 1.5e-24 85.0 35.1 8.3e-06 25.3 0.3 7.1 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP01063.1 - 1.1e-16 58.2 38.0 0.35 11.0 0.2 12.5 14 0 0 14 14 12 6 Leucine Rich Repeat I-set PF07679.11 KFP01063.1 - 1.3e-14 53.8 0.0 2.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_7 PF13504.1 KFP01063.1 - 3.3e-08 32.4 38.3 2 8.9 0.3 11.6 12 0 0 12 12 11 4 Leucine rich repeat Ig_2 PF13895.1 KFP01063.1 - 3e-07 30.4 0.0 6.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP01063.1 - 1.6e-06 28.5 0.0 4.9e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP01063.1 - 0.0005 19.9 0.0 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 KFP01063.1 - 0.041 14.0 0.0 0.13 12.3 0.0 2.0 1 0 0 1 1 1 0 Immunoglobulin domain LRR_6 PF13516.1 KFP01063.1 - 0.058 13.4 42.1 1.9 8.8 0.1 10.7 12 0 0 12 12 11 0 Leucine Rich repeat LRRNT PF01462.13 KFP01063.1 - 0.071 12.6 8.1 0.059 12.8 2.0 3.1 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain LRR_9 PF14580.1 KFP01063.1 - 3.1 7.3 13.3 1.7 8.1 2.8 3.3 1 1 3 4 4 4 0 Leucine-rich repeat HMG_box PF00505.14 KFP01064.1 - 7.6e-19 67.7 1.2 2.7e-18 65.9 0.8 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP01064.1 - 3e-13 49.9 3.4 6.7e-13 48.8 0.4 2.6 1 1 1 2 2 2 1 HMG-box domain Trans_reg_C PF00486.23 KFP01064.1 - 0.0032 17.3 0.5 1.8 8.5 0.0 3.3 2 1 1 3 3 3 2 Transcriptional regulatory protein, C terminal COG5 PF10392.4 KFP01064.1 - 0.04 13.8 4.0 0.055 13.4 1.6 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Pkinase PF00069.20 KFP01065.1 - 2.8e-13 49.6 0.0 8.4e-13 48.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01065.1 - 8.7e-07 28.2 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP01065.1 - 0.019 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tetraspannin PF00335.15 KFP01066.1 - 1.5e-45 155.2 14.2 1.7e-45 155.0 9.9 1.0 1 0 0 1 1 1 1 Tetraspanin family Hum_adeno_E3A PF05393.6 KFP01066.1 - 0.024 14.2 4.2 0.09 12.4 0.2 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Claudin_2 PF13903.1 KFP01066.1 - 0.088 12.5 13.2 0.085 12.5 0.8 2.9 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction NfeD PF01957.13 KFP01066.1 - 0.09 12.9 3.3 0.09 12.9 0.7 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF872 PF05915.7 KFP01066.1 - 0.71 9.7 6.1 1.7 8.5 2.8 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SUR7 PF06687.7 KFP01066.1 - 0.92 9.0 13.1 0.24 10.9 2.2 2.7 3 0 0 3 3 3 0 SUR7/PalI family 7tm_4 PF13853.1 KFP01068.1 - 3.5e-26 91.7 10.5 3.5e-26 91.7 7.3 3.1 3 1 1 4 4 4 2 Olfactory receptor 7tm_1 PF00001.16 KFP01068.1 - 4.4e-20 71.8 12.6 4.4e-20 71.8 8.7 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Reticulon PF02453.12 KFP01068.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.6 3 0 0 3 3 3 0 Reticulon Yae1_N PF09811.4 KFP01069.1 - 1.2e-15 56.6 55.2 1.5e+04 -20.9 38.2 5.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF4205 PF13898.1 KFP01070.1 - 8.7e-59 198.9 0.1 1.1e-43 149.2 0.0 3.0 3 0 0 3 3 3 3 Domain of unknown function (DUF4205) UPF0560 PF10577.4 KFP01071.1 - 0 1272.9 5.3 0 1272.8 3.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 MG1 PF11974.3 KFP01071.1 - 0.011 16.2 0.2 0.075 13.5 0.0 2.4 2 0 0 2 2 2 0 Alpha-2-macroglobulin MG1 domain Alpha_E2_glycop PF00943.14 KFP01071.1 - 0.047 12.3 0.3 0.085 11.4 0.2 1.3 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein Orthoreo_P10 PF07204.6 KFP01071.1 - 0.11 12.2 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF4131 PF13567.1 KFP01071.1 - 0.11 11.8 0.2 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) IncA PF04156.9 KFP01071.1 - 0.32 10.5 0.0 0.32 10.5 0.0 2.5 2 1 0 2 2 2 0 IncA protein Adeno_E3_CR2 PF02439.10 KFP01071.1 - 0.36 10.3 1.9 0.66 9.5 1.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 NMT_C PF02799.10 KFP01072.1 - 1.2e-82 275.9 0.3 3.6e-82 274.3 0.1 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KFP01072.1 - 1.4e-81 271.8 0.0 2.2e-81 271.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_7 PF13508.1 KFP01072.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NST1 PF13945.1 KFP01072.1 - 0.015 15.3 2.9 0.024 14.7 2.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Acetyltransf_9 PF13527.1 KFP01072.1 - 0.017 14.9 0.0 0.079 12.8 0.0 2.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFP01072.1 - 0.044 13.8 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TFIIF_alpha PF05793.7 KFP01072.1 - 5.5 5.2 13.5 6.9 4.9 9.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L7Ae PF01248.21 KFP01073.1 - 2.6e-08 33.2 0.0 5.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KFP01073.1 - 2.1e-05 24.4 0.0 0.008 16.0 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 ACBP PF00887.14 KFP01074.1 - 8.8e-32 108.6 0.5 9.5e-32 108.5 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 KFP01074.1 - 0.15 12.2 0.1 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 FERM central domain Carn_acyltransf PF00755.15 KFP01075.1 - 2.2e-186 620.5 0.0 2.4e-186 620.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Vasohibin PF14822.1 KFP01075.1 - 0.058 12.4 1.1 3.8 6.5 0.1 2.7 3 0 0 3 3 3 0 Vasohibin RUN PF02759.14 KFP01076.1 - 6.4e-29 100.3 0.0 1.6e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 RUN domain Drf_FH3 PF06367.11 KFP01076.1 - 0.023 14.1 3.7 0.06 12.7 2.5 1.8 1 1 0 1 1 1 0 Diaphanous FH3 Domain DUF4477 PF14780.1 KFP01076.1 - 0.029 13.7 0.5 0.27 10.5 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Mito_carr PF00153.22 KFP01077.1 - 3.2e-65 215.8 0.4 1.2e-22 79.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Reprolysin PF01421.14 KFP01078.1 - 1.9e-55 187.5 0.0 4.2e-55 186.4 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.7 KFP01078.1 - 3.3e-20 72.2 5.5 3.3e-20 72.2 3.8 3.9 3 2 0 3 3 3 1 ADAM cysteine-rich Disintegrin PF00200.18 KFP01078.1 - 4.8e-18 65.1 29.3 4.8e-18 65.1 20.3 3.5 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 KFP01078.1 - 3.1e-15 56.1 0.7 5.5e-15 55.3 0.5 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_3 PF13582.1 KFP01078.1 - 3.1e-09 37.4 0.0 6.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFP01078.1 - 1.2e-06 28.5 0.0 4.1e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFP01078.1 - 0.00018 21.1 0.1 0.0006 19.3 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP01078.1 - 0.00032 20.8 0.1 0.0053 16.8 0.1 2.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFP01078.1 - 0.0036 17.4 11.4 0.0036 17.4 7.9 6.5 4 2 1 5 5 5 1 EGF-like domain EF-hand_1 PF00036.27 KFP01079.1 - 9e-17 59.0 0.4 0.00011 21.2 0.0 5.2 5 1 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFP01079.1 - 1.9e-15 56.1 0.2 3.2e-13 49.0 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP01079.1 - 7.3e-12 44.1 0.8 0.0058 16.4 0.0 4.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KFP01079.1 - 1.6e-11 44.1 0.1 0.0004 20.4 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP01079.1 - 5.5e-11 41.2 0.2 0.0087 15.3 0.0 3.5 3 0 0 3 3 3 3 EF hand Ferric_reduct PF01794.14 KFP01080.1 - 2e-23 82.8 5.7 2e-23 82.8 4.0 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component F420_oxidored PF03807.12 KFP01080.1 - 7.8e-12 45.4 0.0 1.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KFP01080.1 - 0.00028 20.3 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 KFP01080.1 - 0.00035 19.7 0.0 0.0006 19.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFP01080.1 - 0.00084 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.4 KFP01080.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain NAD_binding_10 PF13460.1 KFP01080.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding zf-C2H2_jaz PF12171.3 KFP01082.1 - 1.1e-05 25.4 10.0 1.1e-05 25.4 6.9 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Ferric_reduct PF01794.14 KFP01083.1 - 3.5e-18 65.8 12.1 2e-16 60.2 5.3 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component DUF999 PF06198.6 KFP01083.1 - 2.7 7.7 5.7 1.9 8.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF999) DUF3671 PF12420.3 KFP01083.1 - 8.2 6.4 10.2 6.3 6.8 1.9 3.0 1 1 1 2 2 2 0 Protein of unknown function Ferric_reduct PF01794.14 KFP01084.1 - 5.2e-20 71.8 7.7 4.3e-19 68.8 3.4 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component F420_oxidored PF03807.12 KFP01084.1 - 6.4e-18 64.9 0.0 1.2e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFP01084.1 - 3.7e-06 26.8 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFP01084.1 - 0.001 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KFP01084.1 - 0.0028 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF202 PF02656.10 KFP01084.1 - 0.0092 16.1 4.4 0.2 11.9 0.3 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF202) IlvN PF07991.7 KFP01084.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Neurensin PF14927.1 KFP01084.1 - 0.11 11.8 0.4 4.6 6.6 0.1 2.4 2 0 0 2 2 2 0 Neurensin PIN PF01850.16 KFP01085.1 - 0.017 15.4 0.1 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 PIN domain DUF2435 PF10363.4 KFP01085.1 - 0.047 13.5 0.8 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) MMR_HSR1 PF01926.18 KFP01087.1 - 6.7e-21 74.4 0.0 1.1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 KFP01087.1 - 1.5e-16 60.4 5.9 2.1e-15 56.6 4.1 2.3 1 1 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.13 KFP01087.1 - 3.7e-11 42.5 0.1 2.4e-10 39.9 0.0 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFP01087.1 - 1.6e-05 24.4 0.1 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KFP01087.1 - 0.00021 20.1 0.1 0.3 9.8 0.0 2.2 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 KFP01087.1 - 0.066 13.0 1.9 5.1 6.8 0.0 2.9 1 1 2 3 3 3 0 Dynamin family Miro PF08477.8 KFP01087.1 - 0.11 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 KFP01087.1 - 0.13 11.6 0.3 6.4 6.1 0.0 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Claudin_2 PF13903.1 KFP01088.1 - 4e-07 29.8 11.4 6.5e-07 29.2 7.9 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP01088.1 - 0.0014 18.2 5.0 0.0021 17.7 3.5 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family IncA PF04156.9 KFP01089.1 - 1e-07 31.7 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 IncA protein CD34_antigen PF06365.7 KFP01089.1 - 1.1e-05 25.1 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family EphA2_TM PF14575.1 KFP01089.1 - 0.00064 20.0 0.0 0.00095 19.5 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KFP01089.1 - 0.00091 19.4 0.5 0.00093 19.4 0.3 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KFP01089.1 - 0.0029 15.9 0.1 0.0034 15.7 0.1 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E FAM163 PF15069.1 KFP01089.1 - 0.0033 17.9 0.2 0.0065 17.0 0.2 1.5 1 0 0 1 1 1 1 FAM163 family DUF3609 PF12259.3 KFP01089.1 - 0.0051 15.5 0.0 0.0068 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) Corona_S2 PF01601.11 KFP01089.1 - 0.0056 14.8 1.4 0.0082 14.2 0.9 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein DUF4500 PF14937.1 KFP01089.1 - 0.0076 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) UPF0560 PF10577.4 KFP01089.1 - 0.013 13.8 0.5 0.013 13.7 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LST1 PF05083.8 KFP01089.1 - 0.021 14.8 1.3 0.041 13.8 0.9 1.6 1 0 0 1 1 1 0 LST-1 protein TMEM154 PF15102.1 KFP01089.1 - 0.024 14.3 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.6 KFP01089.1 - 0.029 14.0 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Protocadherin FAM176 PF14851.1 KFP01089.1 - 0.049 13.3 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 FAM176 family DUF2681 PF10883.3 KFP01089.1 - 0.078 13.1 0.1 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) GP41 PF00517.12 KFP01089.1 - 0.092 12.2 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein BatD PF13584.1 KFP01089.1 - 0.098 11.2 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF3481 PF11980.3 KFP01089.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) DUF1191 PF06697.7 KFP01089.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) YopD PF05844.7 KFP01089.1 - 0.16 11.0 0.0 0.2 10.6 0.0 1.0 1 0 0 1 1 1 0 YopD protein Adeno_E3_CR2 PF02439.10 KFP01089.1 - 0.25 10.9 9.6 0.58 9.7 6.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Orthoreo_P10 PF07204.6 KFP01089.1 - 0.68 9.7 4.6 0.72 9.6 2.3 1.7 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 Prominin PF05478.6 KFP01089.1 - 1.5 6.2 6.0 1.8 5.9 4.2 1.1 1 0 0 1 1 1 0 Prominin EF-1_beta_acid PF10587.4 KFP01089.1 - 1.6 8.9 6.9 2.6 8.2 4.8 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Synaptobrevin PF00957.16 KFP01089.1 - 3.5 7.3 6.5 1.2 8.8 2.5 1.7 2 0 0 2 2 2 0 Synaptobrevin Pkinase PF00069.20 KFP01090.1 - 3.6e-66 222.9 0.0 4.5e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01090.1 - 1.5e-32 112.7 0.0 2.1e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP01090.1 - 0.00072 18.6 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP01090.1 - 0.0018 18.0 0.0 0.078 12.6 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Frizzled PF01534.12 KFP01091.1 - 3.1e-153 509.3 14.8 3.5e-153 509.1 10.2 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 KFP01091.1 - 6.9e-05 21.8 2.8 6.9e-05 21.8 1.9 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor zf-DHHC PF01529.15 KFP01091.1 - 0.6 9.4 9.0 0.21 10.9 0.1 2.9 2 1 1 3 3 3 0 DHHC palmitoyltransferase p450 PF00067.17 KFP01092.1 - 1.7e-77 260.8 0.0 2.1e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FERM_M PF00373.13 KFP01093.1 - 2.5e-20 72.9 0.1 6.9e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 FERM central domain Ank_5 PF13857.1 KFP01093.1 - 9.4e-18 63.8 0.3 1.5e-10 40.9 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFP01093.1 - 6.9e-16 58.3 0.0 1.5e-08 34.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP01093.1 - 2.3e-12 47.0 0.5 5.3e-07 29.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP01093.1 - 2.9e-12 45.7 0.2 0.0026 17.4 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFP01093.1 - 7.2e-10 38.1 0.1 0.011 15.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat IBR PF01485.16 KFP01094.1 - 9.8e-23 79.8 35.6 1.4e-13 50.4 0.9 5.0 4 1 1 5 5 5 2 IBR domain Ank_2 PF12796.2 KFP01094.1 - 9.4e-16 57.9 0.4 3e-10 40.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP01094.1 - 1.2e-12 47.5 0.9 5.2e-08 32.8 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP01094.1 - 5.8e-12 44.7 0.0 1.7e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFP01094.1 - 1.1e-07 32.1 0.6 0.0068 16.9 0.0 3.6 4 1 1 5 5 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01094.1 - 7.6e-07 28.7 1.7 0.005 16.9 0.0 3.5 3 0 0 3 3 2 2 Ankyrin repeat zf-RING_2 PF13639.1 KFP01094.1 - 3.9e-05 23.3 31.5 9.5e-05 22.1 3.7 3.8 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.1 KFP01094.1 - 0.0027 17.5 6.5 0.0027 17.5 4.5 4.2 3 1 1 4 4 4 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFP01094.1 - 0.0046 16.5 6.1 0.0046 16.5 4.2 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP01094.1 - 0.0081 16.1 8.9 0.0081 16.1 6.2 4.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) UIM PF02809.15 KFP01094.1 - 0.018 14.5 1.8 0.036 13.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-RING_UBOX PF13445.1 KFP01094.1 - 3.3 7.5 21.0 0.021 14.5 2.8 4.4 4 0 0 4 4 4 0 RING-type zinc-finger Sipho_Gp37 PF14594.1 KFP01095.1 - 0.14 11.4 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein AAA PF00004.24 KFP01096.1 - 1.8e-58 196.4 0.0 8.2e-43 145.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KFP01096.1 - 5.3e-25 87.2 0.0 1.2e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PEX-2N PF09263.5 KFP01096.1 - 3.7e-18 65.6 0.0 9.5e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_17 PF13207.1 KFP01096.1 - 1.4e-09 38.8 0.0 0.00027 21.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFP01096.1 - 1.5e-09 38.0 2.4 0.00073 19.5 0.0 3.7 3 1 0 3 3 2 2 AAA ATPase domain AAA_19 PF13245.1 KFP01096.1 - 1.3e-07 31.2 0.3 0.016 14.9 0.1 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 KFP01096.1 - 2.7e-07 30.5 0.0 0.0053 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KFP01096.1 - 3.5e-07 30.3 0.0 0.005 17.0 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_5 PF07728.9 KFP01096.1 - 1.3e-06 28.1 0.2 0.074 12.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 KFP01096.1 - 2.5e-06 27.5 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 KFP01096.1 - 2.9e-06 26.4 0.0 0.00025 20.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 KFP01096.1 - 5.7e-06 26.0 7.0 0.0079 15.8 1.0 4.9 4 1 0 4 4 4 1 NACHT domain AAA_33 PF13671.1 KFP01096.1 - 6.1e-06 26.1 0.0 0.12 12.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KFP01096.1 - 6.3e-06 26.1 0.0 0.0019 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFP01096.1 - 7e-06 25.2 0.0 0.00067 18.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KFP01096.1 - 1.5e-05 24.5 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KFP01096.1 - 3e-05 23.5 2.1 0.82 9.0 0.0 3.5 2 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 KFP01096.1 - 3.3e-05 22.7 0.3 0.02 13.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 KFP01096.1 - 5.4e-05 23.5 0.0 0.099 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFP01096.1 - 6.4e-05 22.4 0.1 0.12 11.8 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 KFP01096.1 - 8.7e-05 22.5 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFP01096.1 - 9.5e-05 22.5 3.2 0.28 11.3 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFP01096.1 - 9.9e-05 21.7 1.7 0.0036 16.8 0.6 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 KFP01096.1 - 9.9e-05 21.3 0.0 0.031 13.1 0.0 2.5 3 0 0 3 3 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 KFP01096.1 - 0.00013 21.1 0.1 0.21 10.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KFP01096.1 - 0.0031 16.7 0.3 1.6 7.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KFP01096.1 - 0.0065 16.7 6.2 0.098 12.9 0.6 3.5 3 1 1 4 4 2 1 ABC transporter KaiC PF06745.8 KFP01096.1 - 0.0069 15.5 0.2 0.65 9.0 0.0 2.3 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.17 KFP01096.1 - 0.0091 14.8 0.4 1.2 7.9 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Hpr_kinase_C PF07475.7 KFP01096.1 - 0.045 13.0 0.6 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Molydop_binding PF01568.16 KFP01096.1 - 0.056 13.2 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 1 0 Molydopterin dinucleotide binding domain AAA_24 PF13479.1 KFP01096.1 - 0.057 12.9 0.5 1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KFP01096.1 - 0.064 12.9 0.4 0.22 11.1 0.0 2.1 2 0 0 2 2 1 0 Adenylylsulphate kinase PhoH PF02562.11 KFP01096.1 - 0.092 11.9 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Miro PF08477.8 KFP01096.1 - 0.096 13.1 0.0 0.83 10.1 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein NTPase_1 PF03266.10 KFP01096.1 - 0.11 12.1 0.3 0.74 9.5 0.0 2.2 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 KFP01096.1 - 0.11 11.9 0.1 0.98 8.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KFP01096.1 - 0.12 11.7 1.7 0.2 11.0 0.0 2.2 3 0 0 3 3 2 0 AAA-like domain CoaE PF01121.15 KFP01096.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase MobB PF03205.9 KFP01096.1 - 0.13 11.9 0.2 0.4 10.3 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KFP01096.1 - 0.15 11.7 0.1 4.8 6.7 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 KFP01096.1 - 0.23 11.0 0.7 8.8 5.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 KFP01096.1 - 0.23 11.0 0.5 2.6 7.6 0.1 2.6 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 KFP01096.1 - 1.4 9.2 5.8 0.23 11.7 0.3 2.4 3 0 0 3 3 1 0 AAA domain RRM_5 PF13893.1 KFP01097.1 - 2.1e-07 30.6 0.1 4.3e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFP01097.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 EF-hand_7 PF13499.1 KFP01098.1 - 1.6e-17 63.3 2.0 6.4e-14 51.8 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP01098.1 - 2.1e-16 57.8 3.0 2.4e-06 26.4 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFP01098.1 - 4.3e-14 51.0 1.4 8.6e-06 25.2 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFP01098.1 - 3.5e-12 45.0 0.1 1.4e-05 24.1 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KFP01098.1 - 1.5e-11 43.6 6.6 0.0027 17.2 0.3 4.2 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP01098.1 - 0.0083 16.1 0.1 0.7 9.9 0.0 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.6 KFP01098.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 EF-hand Pkinase PF00069.20 KFP01099.1 - 1.4e-69 234.1 0.0 1.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01099.1 - 3.1e-36 124.7 0.0 6.7e-36 123.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFP01099.1 - 3.4e-07 30.2 0.1 0.0016 18.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP01099.1 - 8.9e-05 21.6 0.0 0.0002 20.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP01099.1 - 0.0006 18.8 0.0 0.0013 17.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KFP01099.1 - 0.035 13.4 0.0 0.088 12.1 0.0 1.7 1 1 0 1 1 1 0 RIO1 family I-set PF07679.11 KFP01100.1 - 4.3e-16 58.5 0.0 2.3e-07 30.5 0.0 3.8 4 1 0 4 4 4 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP01100.1 - 3.5e-14 53.0 5.5 2.5e-10 40.6 0.2 3.4 3 2 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFP01100.1 - 1.5e-13 50.5 0.3 7.3e-06 25.8 0.0 4.3 3 1 1 4 4 4 3 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP01100.1 - 1.3e-11 44.4 0.1 8.5e-08 32.2 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFP01100.1 - 3e-10 40.0 0.3 2.2e-05 24.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.7 KFP01100.1 - 0.042 13.7 0.0 0.93 9.4 0.0 2.3 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain DUF2450 PF10475.4 KFP01101.1 - 1.1e-109 365.9 12.6 3.2e-109 364.3 8.7 1.9 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 KFP01101.1 - 1.1e-100 336.1 2.5 1.1e-100 336.1 1.7 1.8 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF4298 PF14131.1 KFP01101.1 - 0.12 12.2 6.6 0.35 10.7 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) 7tm_2 PF00002.19 KFP01102.1 - 4.1e-78 261.8 17.7 5.2e-78 261.4 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP01102.1 - 1.1e-18 66.9 7.0 1.1e-18 66.9 4.9 2.0 2 0 0 2 2 2 1 Hormone receptor domain Kunitz_BPTI PF00014.18 KFP01103.1 - 2.7e-57 190.7 33.5 4.5e-22 78.0 2.8 3.1 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain Prion PF00377.13 KFP01103.1 - 0.0018 17.9 0.6 0.0018 17.9 0.4 1.8 2 0 0 2 2 2 1 Prion/Doppel alpha-helical domain Toxin_2 PF00451.14 KFP01103.1 - 0.23 11.6 7.0 0.29 11.2 0.1 4.1 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 G-gamma PF00631.17 KFP01104.1 - 2.4e-20 72.0 0.1 2.7e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 GGL domain TBPIP PF07106.8 KFP01104.1 - 0.038 13.5 0.7 0.04 13.4 0.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AMP-binding_C_2 PF14535.1 KFP01104.1 - 0.051 13.6 0.1 0.06 13.4 0.1 1.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain HALZ PF02183.13 KFP01104.1 - 0.086 12.5 1.0 0.12 12.0 0.7 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper COG2 PF06148.6 KFP01104.1 - 0.13 12.1 0.7 0.16 11.8 0.5 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Acyl-CoA_dh_1 PF00441.19 KFP01105.1 - 5.9e-40 136.8 0.2 8.2e-40 136.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFP01105.1 - 1.7e-18 65.8 0.9 4.7e-18 64.4 0.5 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFP01105.1 - 5.6e-13 49.2 0.0 9.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFP01105.1 - 8.2e-09 36.0 0.2 1.9e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 KFP01105.1 - 0.083 12.2 0.0 0.33 10.3 0.0 1.9 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal SNARE PF05739.14 KFP01106.1 - 2.7e-11 43.0 0.2 3.2e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.8 KFP01106.1 - 6.1e-05 22.6 0.1 8.2e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Sec20 Use1 PF09753.4 KFP01106.1 - 0.0017 17.8 0.0 0.002 17.6 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.1 KFP01106.1 - 0.0067 15.4 0.0 0.0072 15.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Polysacc_synt_4 PF04669.8 KFP01106.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis Collagen PF01391.13 KFP01107.1 - 4.5e-166 538.5 678.4 2.6e-10 39.6 24.0 20.8 2 1 15 17 17 17 15 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFP01107.1 - 1.5e-94 315.3 0.0 1.9e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Cas1_AcylT PF07779.7 KFP01109.1 - 4e-211 701.7 33.6 5.4e-211 701.2 23.3 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 KFP01109.1 - 3.3e-29 102.5 0.3 4.5e-29 102.0 0.2 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Sarcoglycan_2 PF05510.8 KFP01110.1 - 1.2e-162 540.6 0.0 1.4e-162 540.4 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon PDZ PF00595.19 KFP01111.1 - 5.2e-14 52.1 3.0 8.5e-14 51.4 1.4 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 KFP01111.1 - 6.1e-10 38.7 0.4 1.4e-09 37.6 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP01111.1 - 1.1e-09 38.3 0.5 2.5e-09 37.1 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_2 PF13180.1 KFP01111.1 - 0.0011 18.8 0.4 0.0037 17.1 0.3 1.9 1 0 0 1 1 1 1 PDZ domain Arylesterase PF01731.15 KFP01112.1 - 7.7e-39 131.5 1.7 1.3e-38 130.8 1.2 1.4 1 0 0 1 1 1 1 Arylesterase SGL PF08450.7 KFP01112.1 - 1.4e-07 31.1 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KFP01112.1 - 0.0019 18.1 0.0 0.005 16.8 0.0 1.6 1 0 0 1 1 1 1 Strictosidine synthase Ank_2 PF12796.2 KFP01113.1 - 8.2e-59 195.9 30.7 1.3e-16 60.6 0.9 4.6 2 2 5 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01113.1 - 2.5e-29 99.5 15.7 0.0001 21.9 0.0 8.0 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KFP01113.1 - 3.3e-23 81.5 9.1 5.1e-08 33.2 0.3 6.7 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP01113.1 - 9.4e-19 67.0 10.0 0.0023 18.1 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01113.1 - 2.5e-15 55.0 18.2 0.018 15.2 0.2 8.4 9 1 0 9 9 9 4 Ankyrin repeat SOCS_box PF07525.11 KFP01113.1 - 4.3e-13 48.8 4.2 8.4e-13 47.9 2.9 1.5 1 0 0 1 1 1 1 SOCS box DUF3631 PF12307.3 KFP01113.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) BCDHK_Adom3 PF10436.4 KFP01114.1 - 9.2e-50 168.3 0.1 1.3e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFP01114.1 - 1.3e-19 69.9 0.0 2.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFP01114.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.27 KFP01115.1 - 2.4e-14 52.5 14.3 2.7e-06 27.0 0.3 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Mito_carr PF00153.22 KFP01116.1 - 8.9e-74 243.2 0.7 4.1e-27 93.7 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KFP01116.1 - 3.2e-10 38.5 1.0 0.047 13.0 0.1 5.5 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 KFP01116.1 - 1e-09 37.4 0.6 0.0048 16.6 0.0 5.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 KFP01116.1 - 7.1e-08 32.4 1.8 0.032 14.3 0.0 4.7 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP01116.1 - 2.7e-06 26.9 2.1 0.15 11.6 0.0 4.4 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP01116.1 - 2.8e-05 23.2 0.3 1.1 8.7 0.0 3.9 3 0 0 3 3 3 2 EF hand DSS1_SEM1 PF05160.8 KFP01117.1 - 1.6e-12 47.0 10.7 1.7e-12 46.9 7.4 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Homeobox PF00046.24 KFP01118.1 - 4.1e-21 74.3 2.4 5.6e-21 73.9 1.7 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP01118.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 KFP01118.1 - 0.04 12.9 0.1 0.073 12.1 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DLL_N PF12413.3 KFP01119.1 - 1.4e-25 90.1 22.2 1.4e-25 90.1 15.4 2.0 2 0 0 2 2 2 1 Homeobox protein distal-less-like N terminal Homeobox PF00046.24 KFP01119.1 - 2.1e-20 72.0 2.4 3.2e-20 71.4 1.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP01119.1 - 0.037 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain Gp-FAR-1 PF05823.7 KFP01120.1 - 0.029 14.3 0.6 0.032 14.1 0.4 1.0 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1825 PF08855.5 KFP01120.1 - 0.039 13.9 1.1 0.048 13.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) CEP19 PF14933.1 KFP01120.1 - 0.058 13.6 0.5 0.063 13.5 0.3 1.1 1 0 0 1 1 1 0 CEP19-like protein Tup_N PF08581.5 KFP01120.1 - 0.071 13.3 2.3 0.084 13.0 1.6 1.1 1 0 0 1 1 1 0 Tup N-terminal FlxA PF14282.1 KFP01120.1 - 4.8 7.1 8.2 0.93 9.4 0.2 2.0 1 1 1 2 2 2 0 FlxA-like protein Tachykinin PF02202.11 KFP01121.1 - 1.8e-10 39.4 1.1 0.00063 19.1 0.6 2.4 2 0 0 2 2 2 2 Tachykinin family Pro-rich PF15240.1 KFP01121.1 - 0.067 13.2 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Proline-rich Beta-TrCP_D PF12125.3 KFP01121.1 - 0.1 12.2 1.0 0.22 11.1 0.7 1.6 1 1 0 1 1 1 0 D domain of beta-TrCP TraW_N PF12477.3 KFP01121.1 - 0.11 12.4 0.9 0.17 11.8 0.6 1.2 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Bombesin PF02044.12 KFP01121.1 - 1.2 8.6 5.1 4.4 6.8 0.4 2.4 2 0 0 2 2 2 0 Bombesin-like peptide Asn_synthase PF00733.16 KFP01122.1 - 5.3e-63 212.8 0.0 7e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFP01122.1 - 5.8e-26 90.6 0.0 1e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFP01122.1 - 5.4e-21 74.9 0.0 1.4e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KFP01122.1 - 9.5e-09 34.4 0.0 0.00014 20.6 0.0 2.4 1 1 0 2 2 2 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 KFP01122.1 - 1.4e-07 31.0 0.0 2.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KFP01122.1 - 0.0073 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 NAD synthase QueC PF06508.8 KFP01122.1 - 0.02 14.1 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KFP01122.1 - 0.033 12.7 0.0 0.049 12.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Fringe PF02434.11 KFP01123.1 - 7.4e-15 54.8 2.2 2.4e-14 53.1 0.9 2.0 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.16 KFP01123.1 - 4.3e-09 36.2 0.8 5.4e-05 22.8 0.4 2.2 1 1 1 2 2 2 2 Galactosyltransferase VWA PF00092.23 KFP01124.1 - 2.9e-62 209.5 7.5 5.3e-37 127.2 0.4 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain Collagen PF01391.13 KFP01124.1 - 2.3e-58 193.5 291.1 9.5e-08 31.4 16.6 11.8 3 1 7 10 10 10 8 Collagen triple helix repeat (20 copies) VWA_2 PF13519.1 KFP01124.1 - 3.2e-28 98.9 0.4 1e-14 55.0 0.1 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 KFP01124.1 - 5.5e-10 39.1 0.5 9.7e-05 22.0 0.1 3.1 3 0 0 3 3 3 2 von Willebrand factor type A domain DUF1194 PF06707.6 KFP01124.1 - 0.00022 20.2 0.4 0.068 12.1 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_CoxE PF05762.9 KFP01124.1 - 0.00076 18.6 0.0 0.007 15.5 0.0 2.0 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Rep_fac-A_3 PF08661.6 KFP01125.1 - 9.1e-33 112.4 0.0 1.1e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF356 PF04009.7 KFP01125.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF356) FAM117 PF15388.1 KFP01128.1 - 2.2e-122 408.3 23.3 2.2e-122 408.3 16.2 1.9 1 1 1 2 2 2 1 Protein Family FAM117 Arfaptin PF06456.8 KFP01129.1 - 4.2e-89 297.8 11.6 7.2e-89 297.0 8.1 1.4 1 0 0 1 1 1 1 Arfaptin-like domain ICA69 PF04629.9 KFP01129.1 - 4.9e-57 193.6 19.7 2.5e-56 191.3 11.1 2.5 2 1 0 2 2 2 1 Islet cell autoantigen ICA69, C-terminal domain BAR_2 PF10455.4 KFP01129.1 - 0.00094 18.1 3.2 0.0012 17.8 1.8 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking MitMem_reg PF13012.1 KFP01129.1 - 1.3 9.1 11.1 5.2 7.1 0.5 3.8 3 2 0 3 3 3 0 Maintenance of mitochondrial structure and function Neurexophilin PF06312.7 KFP01130.1 - 1e-112 374.7 3.2 1.3e-112 374.4 2.2 1.1 1 0 0 1 1 1 1 Neurexophilin NigD PF12667.2 KFP01130.1 - 0.029 14.1 0.3 0.075 12.8 0.0 1.8 1 1 1 2 2 2 0 NigD-like protein Filamin PF00630.14 KFP01130.1 - 0.039 14.5 0.0 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 Filamin/ABP280 repeat Nepo_coat_C PF03688.9 KFP01130.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain B12D PF06522.6 KFP01131.1 - 8.4e-29 99.0 0.0 9.1e-29 98.9 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit TSP_1 PF00090.14 KFP01132.1 - 2.7e-58 193.8 227.6 8.5e-13 48.2 4.8 23.7 26 1 0 26 26 26 18 Thrombospondin type 1 domain DUF1356 PF07092.7 KFP01133.1 - 3.2e-118 393.1 4.7 3.8e-118 392.8 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) DnaJ_CXXCXGXG PF00684.14 KFP01133.1 - 0.096 12.7 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 DnaJ central domain EGF PF00008.22 KFP01134.1 - 1.2e-14 53.9 60.0 4e-05 23.4 5.4 4.5 4 0 0 4 4 4 4 EGF-like domain EGF_2 PF07974.8 KFP01134.1 - 2.3e-12 46.8 67.0 0.0013 18.8 8.0 4.2 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.2 KFP01134.1 - 9.5e-07 28.5 39.8 0.00039 20.3 1.1 6.3 5 1 0 5 5 5 3 Human growth factor-like EGF Laminin_EGF PF00053.19 KFP01134.1 - 1.4 8.8 50.2 25 4.8 10.2 4.2 1 1 3 4 4 4 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFP01135.1 - 4e-19 68.4 80.1 0.00022 21.2 7.7 5.2 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.2 KFP01135.1 - 9.3e-17 59.8 53.3 0.00063 19.6 3.3 7.0 5 0 0 5 5 5 5 Human growth factor-like EGF EGF PF00008.22 KFP01135.1 - 4.3e-16 58.5 68.0 8.4e-05 22.4 7.4 5.6 4 1 1 5 5 5 5 EGF-like domain Laminin_EGF PF00053.19 KFP01135.1 - 1.2 9.0 65.5 4.7 7.2 3.5 5.2 2 1 3 5 5 5 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 KFP01136.1 - 0.001 18.9 18.3 0.0014 18.5 4.8 4.4 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.2 KFP01136.1 - 0.027 14.5 0.1 0.027 14.5 0.1 4.4 4 0 0 4 4 4 0 Human growth factor-like EGF VWD PF00094.20 KFP01137.1 - 0.0029 17.7 0.8 0.0055 16.8 0.6 1.4 1 0 0 1 1 1 1 von Willebrand factor type D domain Gelsolin PF00626.17 KFP01138.1 - 1.1e-88 290.9 0.8 5.8e-19 67.5 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat DUF669 PF05037.8 KFP01138.1 - 0.035 13.9 0.6 0.089 12.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF669) Arf PF00025.16 KFP01139.1 - 3.3e-67 225.0 0.0 3.8e-67 224.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP01139.1 - 1.7e-17 63.3 0.0 1.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01139.1 - 8.4e-15 55.3 0.1 1.2e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFP01139.1 - 4.8e-12 45.4 0.1 4.8e-12 45.4 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFP01139.1 - 1.2e-07 30.7 0.5 1e-06 27.7 0.3 2.0 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFP01139.1 - 3.5e-06 26.6 0.1 1.5e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP01139.1 - 7.9e-06 25.8 0.1 1.1e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP01139.1 - 2.2e-05 23.7 0.0 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KFP01139.1 - 0.0044 16.5 0.0 0.014 14.9 0.0 1.6 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KFP01139.1 - 0.017 15.0 0.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 KFP01139.1 - 0.021 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ACT PF01842.20 KFP01139.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain ETS_PEA3_N PF04621.8 KFP01141.1 - 1.8e-147 491.0 21.1 2.4e-147 490.6 14.6 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.17 KFP01141.1 - 7.5e-38 128.5 0.2 1.2e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Ets-domain DAG_kinase_N PF14513.1 KFP01142.1 - 1.6e-59 200.0 0.0 8.1e-59 197.7 0.0 2.2 2 0 0 2 2 2 1 Diacylglycerol kinase N-terminus DAGK_acc PF00609.14 KFP01142.1 - 1.2e-55 188.0 0.0 2.7e-55 186.9 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFP01142.1 - 2.9e-30 104.3 0.0 5.1e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFP01142.1 - 1.3e-20 72.8 35.0 2.2e-12 46.4 5.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.27 KFP01142.1 - 7.5e-12 43.6 4.3 1.1e-05 24.4 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFP01142.1 - 2.8e-09 36.9 0.3 2.8e-09 36.9 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP01142.1 - 3.4e-09 35.8 0.3 8.7e-05 22.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFP01142.1 - 6.7e-08 32.0 3.0 0.016 14.7 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP01142.1 - 1e-07 30.9 0.1 0.02 14.2 0.0 2.6 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 KFP01142.1 - 4e-05 23.5 0.2 0.00025 21.0 0.1 2.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region FA_hydroxylase PF04116.8 KFP01144.1 - 1.6e-19 70.4 14.8 3.6e-19 69.2 10.3 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Homeobox PF00046.24 KFP01145.1 - 1.1e-14 53.7 7.0 1.1e-14 53.7 4.9 1.8 2 0 0 2 2 2 1 Homeobox domain Trep_dent_lipo PF09710.5 KFP01145.1 - 0.015 13.9 1.0 0.02 13.5 0.7 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) IspD PF01128.14 KFP01146.1 - 2.2e-30 105.8 0.0 3.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FAM180 PF15173.1 KFP01146.1 - 0.015 15.1 0.4 0.8 9.4 0.1 2.3 1 1 1 2 2 2 0 FAM180 family Sclerostin PF05463.6 KFP01147.1 - 4.4e-101 336.4 6.4 4.9e-101 336.2 4.4 1.0 1 0 0 1 1 1 1 Sclerostin (SOST) Cys_knot PF00007.17 KFP01147.1 - 3.5e-05 23.8 7.6 0.00018 21.5 5.3 1.9 1 1 0 1 1 1 1 Cystine-knot domain DAN PF03045.10 KFP01147.1 - 5.3e-05 22.6 1.6 9.6e-05 21.7 1.1 1.4 1 0 0 1 1 1 1 DAN domain DUF977 PF06163.6 KFP01147.1 - 0.053 13.2 0.4 0.095 12.4 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) LRR_4 PF12799.2 KFP01148.1 - 4.1e-18 64.5 8.2 5.1e-08 32.3 0.0 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFP01148.1 - 4.1e-17 62.3 5.3 5.2e-16 58.6 0.8 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 KFP01148.1 - 2.9e-12 46.1 9.6 9.7e-09 34.8 4.6 2.4 1 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFP01148.1 - 2.4e-07 29.8 11.9 0.41 10.8 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFP01148.1 - 1.8e-06 27.2 11.3 0.28 11.5 0.3 5.5 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KFP01148.1 - 0.00016 21.3 9.7 1.2 9.3 0.5 4.5 3 1 1 4 4 4 2 Leucine Rich repeat Ank PF00023.25 KFP01149.1 - 7.8e-17 60.1 1.3 2.4e-09 36.5 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KFP01149.1 - 1.6e-15 57.1 0.7 4e-14 52.7 0.1 2.7 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFP01149.1 - 3.4e-13 48.4 1.4 2.7e-08 33.2 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFP01149.1 - 2.2e-12 46.7 1.3 3.3e-06 27.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.13 KFP01149.1 - 1.6e-09 37.4 12.9 1.6e-09 37.4 8.9 2.5 2 0 0 2 2 2 1 MYND finger Ank_4 PF13637.1 KFP01149.1 - 1.8e-09 37.8 0.1 2.6e-08 34.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TraV PF09676.5 KFP01149.1 - 0.12 13.0 1.9 0.21 12.3 1.3 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) zf-Mss51 PF13824.1 KFP01149.1 - 0.7 9.7 6.1 2.2 8.1 4.2 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 W2 PF02020.13 KFP01150.1 - 2e-23 82.1 4.0 2e-23 82.1 2.7 3.0 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DIL PF01843.14 KFP01150.1 - 0.0066 16.3 6.0 7.3 6.5 0.1 4.5 4 1 1 5 5 5 2 DIL domain Tetraspannin PF00335.15 KFP01151.1 - 1.5e-20 73.4 14.8 2e-20 73.0 10.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF843 PF05814.6 KFP01151.1 - 0.043 13.5 2.1 0.072 12.8 1.5 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) CcoS PF03597.10 KFP01151.1 - 0.049 13.0 1.9 0.049 13.0 1.3 3.4 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type DIE2_ALG10 PF04922.7 KFP01151.1 - 0.081 11.9 3.2 0.14 11.2 2.2 1.3 1 0 0 1 1 1 0 DIE2/ALG10 family DUF3278 PF11683.3 KFP01151.1 - 0.098 12.6 0.9 0.13 12.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) EPV_E5 PF08135.6 KFP01151.1 - 0.35 10.8 10.4 1.1 9.2 7.1 2.0 1 1 0 1 1 1 0 Major transforming protein E5 family ABC2_membrane PF01061.19 KFP01151.1 - 7.9 5.5 15.6 1.9 7.5 8.5 1.6 2 0 0 2 2 2 0 ABC-2 type transporter DUF2207 PF09972.4 KFP01151.1 - 8.9 4.7 6.1 7.9 4.9 3.6 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Thioredoxin_7 PF13899.1 KFP01152.1 - 8e-20 70.6 0.0 1.7e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFP01153.1 - 2.9e-26 91.2 0.2 5.6e-26 90.3 0.1 1.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredox_DsbH PF03190.10 KFP01153.1 - 1.7e-06 27.8 0.1 2.4e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 KFP01153.1 - 4.1e-05 23.7 0.4 0.0001 22.4 0.3 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain PXA PF02194.10 KFP01154.1 - 8.1e-58 195.0 0.2 2.4e-57 193.4 0.1 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KFP01154.1 - 1.3e-27 96.1 0.2 2.6e-25 88.7 0.1 4.0 2 1 1 3 3 3 1 Sorting nexin C terminal PX PF00787.19 KFP01154.1 - 3.4e-23 81.5 0.5 3.4e-23 81.5 0.4 2.4 2 0 0 2 2 2 1 PX domain RGS PF00615.14 KFP01154.1 - 6.8e-21 74.5 4.5 1.6e-19 70.1 0.1 3.6 3 0 0 3 3 3 1 Regulator of G protein signaling domain COX5A PF02284.11 KFP01154.1 - 0.044 13.7 0.2 1.4 8.8 0.0 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va BLOC1_2 PF10046.4 KFP01154.1 - 0.079 13.1 1.7 0.34 11.0 0.2 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Yae1_N PF09811.4 KFP01155.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Hist_deacetyl PF00850.14 KFP01156.1 - 3.2e-82 276.2 0.0 3.2e-82 276.2 0.0 2.2 3 0 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.3 KFP01156.1 - 1.5e-38 130.6 48.7 1.5e-38 130.6 33.8 3.9 5 0 0 5 5 5 1 Glutamine rich N terminal domain of histone deacetylase 4 HLH PF00010.21 KFP01157.1 - 2.2e-18 65.6 0.4 3.4e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Toxin_trans PF07952.7 KFP01157.1 - 0.0037 16.2 0.0 0.0042 16.0 0.0 1.0 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain RNA_pol_I_A49 PF06870.7 KFP01157.1 - 0.037 12.6 0.3 0.038 12.5 0.2 1.0 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor DUF773 PF05600.7 KFP01157.1 - 0.042 12.6 0.4 0.045 12.5 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF773) AAA_27 PF13514.1 KFP01157.1 - 0.074 10.7 0.2 0.081 10.6 0.1 1.0 1 0 0 1 1 1 0 AAA domain HLH PF00010.21 KFP01158.1 - 3.5e-17 61.8 0.7 3.5e-17 61.8 0.5 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Tom37_C PF11801.3 KFP01158.1 - 0.074 12.9 0.0 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Yae1_N PF09811.4 KFP01159.1 - 8.4e-12 44.4 44.2 1.5e+04 -5.8 30.6 5.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal SHS2_Rpb7-N PF03876.12 KFP01160.1 - 3.5e-05 23.8 0.1 6.4e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KFP01160.1 - 0.005 16.8 0.0 0.02 14.9 0.0 2.1 1 1 0 1 1 1 1 S1 RNA binding domain Chs3p PF12271.3 KFP01161.1 - 0.0078 15.2 0.8 0.012 14.6 0.6 1.3 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit ABC_membrane_3 PF13748.1 KFP01161.1 - 0.1 11.6 0.6 0.21 10.6 0.4 1.5 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF4131 PF13567.1 KFP01161.1 - 6.5 6.1 8.0 0.69 9.3 2.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Death PF00531.17 KFP01162.1 - 1.4e-05 24.7 1.0 0.11 12.2 0.1 3.0 1 1 1 2 2 2 2 Death domain SH3_2 PF07653.12 KFP01162.1 - 0.00022 20.6 0.1 0.0004 19.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain ZU5 PF00791.15 KFP01162.1 - 0.00088 18.9 0.1 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 ZU5 domain Pas_Saposin PF09016.5 KFP01162.1 - 0.049 13.6 0.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Pas factor saposin fold Integrin_beta PF00362.13 KFP01163.1 - 2.6e-135 451.6 0.2 2.6e-135 451.6 0.1 2.0 2 0 0 2 2 2 1 Integrin, beta chain EGF_2 PF07974.8 KFP01163.1 - 5.2e-07 29.7 34.7 3.2e-05 23.9 9.3 4.9 5 0 0 5 5 5 3 EGF-like domain zf-H2C2_2 PF13465.1 KFP01167.1 - 2e-16 59.3 8.7 2.6e-09 36.9 2.0 4.8 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP01167.1 - 1.6e-13 50.1 30.4 2.6e-06 27.4 0.7 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP01167.1 - 1.9e-09 37.1 27.5 0.00013 22.0 1.0 3.7 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP01167.1 - 0.00058 19.9 6.3 0.9 9.7 0.9 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 KFP01167.1 - 0.1 12.1 9.3 1.2 8.7 0.1 3.4 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1 PF03811.8 KFP01167.1 - 0.13 11.7 7.6 1.3 8.5 1.5 2.6 2 0 0 2 2 2 0 InsA N-terminal domain zf-RING_3 PF14369.1 KFP01167.1 - 0.58 10.1 4.3 17 5.5 0.6 2.7 2 0 0 2 2 2 0 zinc-finger zf-met PF12874.2 KFP01167.1 - 1.1 9.5 5.5 15 5.9 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.1 KFP01167.1 - 1.8 8.3 5.5 2.6 7.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 KFP01167.1 - 2 8.4 23.6 0.13 12.1 0.6 3.9 5 0 0 5 5 5 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 KFP01167.1 - 3.5 7.2 6.3 2.9 7.5 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.8 KFP01167.1 - 4.2 7.1 7.0 0.72 9.5 1.6 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 KFP01167.1 - 8.2 6.2 17.1 3.1 7.6 1.1 3.2 1 1 2 3 3 3 0 BED zinc finger zf-Di19 PF05605.7 KFP01167.1 - 8.5 6.5 15.0 0.56 10.3 2.8 3.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-4CXXC_R1 PF10497.4 KFP01168.1 - 6.7e-40 135.4 10.4 1.1e-39 134.7 7.2 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Endonuclease_7 PF02945.10 KFP01168.1 - 8.3 6.2 13.7 0.32 10.7 3.1 2.5 1 1 1 2 2 2 0 Recombination endonuclease VII IL6 PF00489.12 KFP01169.1 - 2.4e-35 121.3 1.5 2.7e-35 121.2 1.1 1.0 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family Exonuc_VII_L PF02601.10 KFP01169.1 - 0.09 11.9 0.3 0.1 11.7 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Hyccin PF09790.4 KFP01170.1 - 5.4e-136 452.4 0.7 7.9e-136 451.9 0.5 1.2 1 0 0 1 1 1 1 Hyccin Kelch_1 PF01344.20 KFP01171.1 - 2.7e-44 148.4 12.3 2.6e-13 49.2 0.3 5.7 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 KFP01171.1 - 4.1e-34 116.4 1.0 4.9e-33 113.0 0.1 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 KFP01171.1 - 4.3e-30 102.6 8.8 3.1e-09 36.5 0.0 6.4 1 1 5 6 6 6 4 Kelch motif BTB PF00651.26 KFP01171.1 - 5.2e-29 100.4 1.2 5.2e-29 100.4 0.8 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFP01171.1 - 3.7e-25 87.4 1.0 4.6e-08 32.6 0.0 6.3 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP01171.1 - 2.2e-21 74.7 6.2 2.8e-06 26.8 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KFP01171.1 - 2.3e-16 59.4 0.9 1.4e-05 25.1 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP01171.1 - 4e-10 39.4 3.0 0.0086 16.0 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.6 KFP01171.1 - 0.0012 17.9 2.0 0.0032 16.5 0.1 2.3 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus UvrD-helicase PF00580.16 KFP01171.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PKD PF00801.15 KFP01173.1 - 4.9e-07 29.3 0.2 1.3e-05 24.8 0.1 2.7 2 0 0 2 2 2 1 PKD domain DUF3042 PF11240.3 KFP01173.1 - 0.13 12.0 0.1 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Oligomerisation PF02410.10 KFP01174.1 - 9e-29 99.4 0.1 1.1e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Oligomerisation domain PP2 PF14299.1 KFP01174.1 - 0.041 13.2 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Phloem protein 2 KH_1 PF00013.24 KFP01175.1 - 5.7e-56 186.0 12.7 2.5e-14 52.6 0.1 4.7 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 KFP01175.1 - 5.7e-38 127.9 12.6 4.9e-09 35.6 0.0 4.8 4 0 0 4 4 4 4 KH domain RRM_1 PF00076.17 KFP01175.1 - 8.3e-17 60.5 0.0 9.3e-09 34.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.12 KFP01175.1 - 4.7e-16 58.1 6.4 0.0018 17.8 0.1 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 KFP01175.1 - 1.4e-14 53.5 0.5 0.0012 18.4 0.0 4.7 4 0 0 4 4 4 4 KH domain RRM_6 PF14259.1 KFP01175.1 - 2.9e-14 52.7 0.0 1.1e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP01175.1 - 4.6e-10 39.1 0.1 7.1e-07 28.9 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_5 PF13184.1 KFP01175.1 - 3.4e-08 33.1 2.6 0.24 11.2 0.1 4.5 4 0 0 4 4 4 3 NusA-like KH domain SLS PF14611.1 KFP01175.1 - 0.035 13.5 7.7 2.7 7.3 0.0 3.5 3 1 1 4 4 4 0 Mitochondrial inner-membrane-bound regulator DUF4041 PF13250.1 KFP01175.1 - 0.12 11.9 1.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Evr1_Alr PF04777.8 KFP01175.1 - 0.16 11.8 0.1 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Erv1 / Alr family LcrG PF07216.7 KFP01175.1 - 0.17 11.9 3.0 1.9 8.5 0.8 2.7 2 0 0 2 2 2 0 LcrG protein RRM_1 PF00076.17 KFP01176.1 - 3.8e-20 71.2 0.0 5.2e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP01176.1 - 1.1e-15 57.2 0.0 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP01176.1 - 1.1e-09 38.0 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KFP01176.1 - 0.11 12.1 52.4 0.024 14.3 24.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 KFP01176.1 - 0.79 8.1 8.5 0.87 7.9 5.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Zip PF02535.17 KFP01176.1 - 3.5 6.5 9.6 4.5 6.1 6.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4525 PF15027.1 KFP01177.1 - 1.1e-73 245.3 1.1 1.2e-73 245.1 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) DUF4475 PF14753.1 KFP01178.1 - 7.2e-93 309.5 3.4 8.7e-93 309.3 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) TUDOR PF00567.19 KFP01179.1 - 2.6e-23 82.1 0.4 6.8e-23 80.8 0.3 1.8 1 0 0 1 1 1 1 Tudor domain Pkinase PF00069.20 KFP01179.1 - 7e-19 67.9 0.0 2.7e-18 66.0 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01179.1 - 1.1e-11 44.2 0.0 2.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SNase PF00565.12 KFP01179.1 - 0.0073 16.5 0.0 0.027 14.7 0.0 1.9 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Agenet PF05641.7 KFP01179.1 - 0.013 15.5 0.7 0.04 14.0 0.1 2.2 2 0 0 2 2 2 0 Agenet domain Phage_int_SAM_1 PF02899.12 KFP01179.1 - 0.015 15.4 0.1 0.04 14.0 0.1 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SMN PF06003.7 KFP01179.1 - 0.051 12.6 0.7 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Hormone_3 PF00159.13 KFP01180.1 - 1.4e-19 69.7 2.3 2.3e-19 69.0 1.6 1.4 1 0 0 1 1 1 1 Pancreatic hormone peptide Gasdermin PF04598.7 KFP01181.1 - 2.7e-130 435.1 6.1 3.1e-130 434.9 4.2 1.0 1 0 0 1 1 1 1 Gasdermin family Oxysterol_BP PF01237.13 KFP01182.1 - 5.3e-133 442.8 0.9 2.1e-132 440.9 0.1 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KFP01182.1 - 3.8e-12 46.0 0.1 1.2e-11 44.4 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFP01182.1 - 1.2e-07 31.8 2.5 1.7e-06 28.1 0.6 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFP01182.1 - 0.0096 16.1 2.6 1 9.6 1.8 3.0 1 1 0 1 1 1 1 Pleckstrin homology domain Cytochrom_C PF00034.16 KFP01183.1 - 2e-11 44.5 0.0 2.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFP01183.1 - 2.4e-07 30.7 2.2 1.7e-06 28.0 1.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KFP01183.1 - 9.7e-05 21.8 3.4 0.0015 18.0 2.3 2.2 1 1 0 1 1 1 1 Cytochrome c-550 domain UPF0128 PF03673.8 KFP01183.1 - 0.033 13.4 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Cytochrom_C1 PF02167.10 KFP01183.1 - 0.16 11.6 0.3 0.2 11.2 0.2 1.4 1 1 0 1 1 1 0 Cytochrome C1 family FARP PF01581.11 KFP01184.1 - 0.62 10.6 3.2 39 5.1 0.0 3.5 3 0 0 3 3 3 0 FMRFamide related peptide family bZIP_Maf PF03131.12 KFP01187.1 - 2.5e-21 75.7 4.4 2.5e-21 75.7 3.0 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 KFP01187.1 - 3.2e-09 36.6 12.0 6.2e-09 35.6 8.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP01187.1 - 1.6e-07 31.0 7.5 3.5e-07 29.9 5.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DUF724 PF05266.9 KFP01187.1 - 0.0048 16.5 2.9 0.0086 15.7 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.17 KFP01187.1 - 0.067 13.2 5.1 0.14 12.1 3.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4472 PF14739.1 KFP01187.1 - 0.14 12.6 5.9 0.12 12.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) RRM_1 PF00076.17 KFP01188.1 - 2.6e-37 126.2 0.0 3.2e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP01188.1 - 1.6e-33 114.5 0.0 8e-17 60.9 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP01188.1 - 9.8e-12 44.5 0.0 4e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KFP01188.1 - 0.012 15.0 0.5 0.52 9.8 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain NID PF07292.8 KFP01188.1 - 0.54 10.3 0.1 0.54 10.3 0.0 2.8 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) Chromo_shadow PF01393.14 KFP01189.1 - 9.1e-41 137.5 0.0 5.6e-35 118.9 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 KFP01189.1 - 1.3e-22 79.2 0.2 3.9e-17 61.6 0.1 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KFP01189.1 - 0.012 15.5 0.2 0.031 14.1 0.1 1.7 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 PX PF00787.19 KFP01190.1 - 4.4e-24 84.4 2.7 5.8e-24 84.0 1.8 1.2 1 0 0 1 1 1 1 PX domain Homeobox PF00046.24 KFP01191.1 - 5.8e-23 80.2 7.4 7.3e-23 79.9 5.1 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP01191.1 - 0.19 11.4 1.8 0.27 10.9 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain DUF4074 PF13293.1 KFP01192.1 - 3.9e-38 129.4 8.2 3.9e-38 129.4 5.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4074) Homeobox PF00046.24 KFP01192.1 - 1e-21 76.2 5.0 2.1e-21 75.3 3.5 1.5 1 0 0 1 1 1 1 Homeobox domain DUF1176 PF06674.6 KFP01192.1 - 4.9 6.1 5.9 7.7 5.5 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Homeobox PF00046.24 KFP01193.1 - 7.6e-22 76.6 8.8 7.6e-22 76.6 6.1 2.0 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFP01193.1 - 0.015 15.0 1.7 0.032 13.9 1.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFP01194.1 - 3.9e-22 77.6 8.2 6.1e-22 77.0 5.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP01194.1 - 0.021 14.5 1.1 0.041 13.5 0.8 1.5 1 0 0 1 1 1 0 Homeobox KN domain Hanta_G1 PF01567.11 KFP01194.1 - 0.11 10.6 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 Homeobox PF00046.24 KFP01195.1 - 6.8e-23 80.0 6.5 7.5e-23 79.9 4.5 1.0 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 KFP01195.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain CI-B14_5a PF07347.7 KFP01195.1 - 0.086 12.6 0.1 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Homeobox_KN PF05920.6 KFP01195.1 - 0.16 11.6 0.7 0.23 11.1 0.4 1.4 1 1 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 KFP01195.1 - 0.19 10.8 0.6 0.4 9.7 0.1 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 KFP01196.1 - 6.5e-21 73.7 6.1 1.2e-20 72.8 4.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP01196.1 - 0.18 11.5 0.2 0.18 11.5 0.2 1.9 2 0 0 2 2 2 0 Homeobox KN domain RNA_pol_Rpc4 PF05132.9 KFP01196.1 - 0.27 11.2 1.9 0.5 10.3 1.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3528 PF12045.3 KFP01197.1 - 2e-67 225.7 1.2 3.5e-67 225.0 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeobox PF00046.24 KFP01197.1 - 2.4e-20 71.8 7.5 3.9e-20 71.2 5.2 1.4 1 0 0 1 1 1 1 Homeobox domain SR-25 PF10500.4 KFP01197.1 - 0.032 13.7 6.0 0.043 13.2 4.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Homeobox_KN PF05920.6 KFP01197.1 - 0.13 12.0 0.4 0.25 11.0 0.3 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFP01198.1 - 2.3e-19 68.7 7.9 2.7e-19 68.5 5.5 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP01198.1 - 0.00041 20.0 2.0 0.00065 19.3 1.4 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFP01198.1 - 0.0094 14.9 0.1 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 KFP01199.1 - 3.9e-21 74.4 4.6 6.3e-21 73.7 3.2 1.3 1 0 0 1 1 1 1 Homeobox domain NAD_binding_2 PF03446.10 KFP01200.1 - 1.4e-52 177.7 0.2 2e-52 177.3 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFP01200.1 - 1.1e-38 131.9 0.1 1.8e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 KFP01200.1 - 7.5e-10 38.2 0.0 1.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFP01200.1 - 1.3e-08 35.1 0.0 3.9e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFP01200.1 - 0.00022 20.9 0.0 0.0005 19.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KFP01200.1 - 0.0034 17.3 0.0 0.015 15.2 0.0 2.1 1 1 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KFP01200.1 - 0.01 15.2 0.0 0.27 10.6 0.0 2.2 1 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDH PF02153.12 KFP01200.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase IlvN PF07991.7 KFP01200.1 - 0.013 14.8 0.1 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF970 PF06153.6 KFP01200.1 - 0.042 13.8 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF970) NAD_Gly3P_dh_N PF01210.18 KFP01200.1 - 0.097 12.3 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zf-C2H2_4 PF13894.1 KFP01201.1 - 0.014 15.7 5.0 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP01201.1 - 0.033 14.5 6.7 1.3 9.4 1.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP01201.1 - 2.6 8.4 15.5 1.7 9.1 1.2 2.7 3 0 0 3 3 3 0 Zinc-finger double domain bZIP_1 PF00170.16 KFP01202.1 - 7.9e-13 48.1 9.1 1.5e-12 47.3 6.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP01202.1 - 8.7e-11 41.4 7.7 8.7e-11 41.4 5.3 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFP01202.1 - 3.2e-05 24.1 5.1 0.0001 22.5 3.5 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 KFP01202.1 - 0.26 10.7 2.5 0.52 9.8 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 KFP01202.1 - 1.2 8.9 4.4 2.8 7.7 3.0 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper RhoGAP PF00620.22 KFP01203.1 - 5.2e-50 168.9 0.0 1.1e-49 168.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 KFP01203.1 - 7.8e-16 57.5 7.2 1.3e-15 56.8 5.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH2 PF00017.19 KFP01203.1 - 3.1e-12 46.1 0.0 9.6e-12 44.5 0.0 1.9 2 0 0 2 2 2 1 SH2 domain zf-RING-like PF08746.6 KFP01203.1 - 0.0032 17.4 4.5 0.0071 16.3 3.1 1.6 1 0 0 1 1 1 1 RING-like domain PHD_2 PF13831.1 KFP01203.1 - 0.041 13.1 1.9 0.09 12.1 1.3 1.5 1 0 0 1 1 1 0 PHD-finger FYVE_2 PF02318.11 KFP01203.1 - 0.44 10.4 7.7 0.55 10.1 4.5 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger WH2 PF02205.15 KFP01204.1 - 2.4e-10 39.6 0.7 4.7e-10 38.7 0.5 1.5 1 0 0 1 1 1 1 WH2 motif Peptidase_C69 PF03577.10 KFP01205.1 - 2.4e-09 36.5 0.0 3.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.11 KFP01205.1 - 0.021 14.3 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FKBP_C PF00254.23 KFP01206.1 - 8.3e-28 96.2 0.0 1.4e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.1 KFP01206.1 - 6.4e-09 35.8 0.7 1.1e-08 35.1 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP01206.1 - 1.1e-06 27.5 5.1 0.014 14.6 1.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 KFP01206.1 - 0.00012 21.2 4.2 0.12 11.7 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP01206.1 - 0.00022 20.8 2.9 0.52 10.3 0.6 2.8 2 0 0 2 2 2 2 EF-hand domain Collagen PF01391.13 KFP01207.1 - 2.1e-28 97.6 94.4 8.7e-10 38.0 15.2 4.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) DUF4215 PF13948.1 KFP01207.1 - 2.5e-05 24.3 13.2 3.5e-05 23.9 4.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4215) TPP_enzyme_M PF00205.17 KFP01208.1 - 3.3e-32 111.0 0.0 1e-31 109.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 KFP01208.1 - 1.2e-30 106.3 0.0 1.2e-28 99.7 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFP01208.1 - 1.2e-27 96.3 0.2 2.6e-27 95.2 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ank_2 PF12796.2 KFP01209.1 - 7.9e-196 635.0 53.6 2.5e-22 79.0 0.1 13.8 2 2 10 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01209.1 - 9.8e-195 621.5 74.7 8.1e-11 41.1 0.1 28.1 28 0 0 28 28 28 27 Ankyrin repeat Ank_4 PF13637.1 KFP01209.1 - 1.7e-158 512.5 49.3 1.4e-14 54.1 0.2 21.1 7 4 16 23 23 23 23 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP01209.1 - 6.2e-143 461.6 63.3 3e-11 43.1 0.2 22.4 7 5 16 23 23 23 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01209.1 - 9.2e-126 396.9 64.2 1.1e-07 31.4 0.1 28.4 29 0 0 29 29 29 26 Ankyrin repeat RVT_1 PF00078.22 KFP01210.1 - 0.034 13.5 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glycos_transf_2 PF00535.21 KFP01211.1 - 1.4e-26 93.1 0.0 2.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP01211.1 - 3e-20 72.4 0.8 5e-20 71.7 0.5 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 KFP01211.1 - 2.4e-07 30.1 0.0 5.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP01211.1 - 6.9e-07 28.6 0.0 1.6e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFP01211.1 - 0.0037 17.6 0.1 0.018 15.4 0.1 2.1 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Hydrolase_6 PF13344.1 KFP01212.1 - 7.3e-09 35.4 0.0 7.6e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Yos1 PF08571.5 KFP01213.1 - 5.2e-29 100.1 0.6 5.8e-29 100.0 0.4 1.0 1 0 0 1 1 1 1 Yos1-like Herpes_UL45 PF05473.7 KFP01214.1 - 0.0018 17.7 1.7 0.0019 17.6 0.7 1.4 1 1 0 1 1 1 1 UL45 protein Lectin_C PF00059.16 KFP01214.1 - 0.045 14.3 0.1 0.093 13.3 0.1 1.5 1 0 0 1 1 1 0 Lectin C-type domain Chordopox_A33R PF05966.7 KFP01214.1 - 0.058 12.1 0.2 0.098 11.4 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF3328 PF11807.3 KFP01214.1 - 0.062 12.9 0.6 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) RabGAP-TBC PF00566.13 KFP01215.1 - 2.1e-19 69.8 2.8 4.6e-15 55.6 0.1 2.5 2 1 1 3 3 3 2 Rab-GTPase-TBC domain 7tm_4 PF13853.1 KFP01216.1 - 2e-37 128.2 14.5 2e-37 128.2 10.0 2.9 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP01216.1 - 1.2e-31 109.7 22.9 1.7e-31 109.3 15.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP01216.1 - 0.034 13.2 27.3 0.56 9.3 18.9 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx EF-hand_7 PF13499.1 KFP01217.1 - 9.1e-22 76.9 10.6 1.6e-08 34.5 0.7 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFP01217.1 - 4.3e-17 60.0 15.3 9.4e-06 24.5 0.1 5.1 6 0 0 6 6 6 4 EF hand EF-hand_5 PF13202.1 KFP01217.1 - 5.8e-13 47.5 10.7 0.0017 17.6 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KFP01217.1 - 1.9e-12 45.9 12.9 0.0018 17.9 0.1 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 KFP01217.1 - 9.4e-08 31.5 13.0 0.019 14.6 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain pair CCDC32 PF14989.1 KFP01217.1 - 0.014 15.1 0.9 0.03 14.1 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing 32 BCNT PF07572.7 KFP01217.1 - 0.17 11.8 0.1 0.17 11.8 0.0 2.2 3 0 0 3 3 3 0 Bucentaur or craniofacial development zf-met PF12874.2 KFP01218.1 - 7.6e-07 29.1 1.6 2.5e-06 27.4 1.1 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP01218.1 - 0.039 14.1 0.5 0.039 14.1 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ETF_alpha PF00766.14 KFP01219.1 - 3.1e-39 132.4 1.5 6e-39 131.5 0.1 2.0 2 1 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 KFP01219.1 - 1.5e-36 125.5 0.2 2.5e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ion_trans PF00520.26 KFP01220.1 - 6e-05 22.3 3.0 6e-05 22.3 2.1 1.6 2 0 0 2 2 2 1 Ion transport protein EGF_2 PF07974.8 KFP01221.1 - 0.0065 16.6 3.8 0.033 14.3 2.7 1.9 1 1 0 1 1 1 1 EGF-like domain EGF PF00008.22 KFP01221.1 - 0.011 15.7 2.2 0.02 14.8 1.6 1.6 1 1 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.19 KFP01221.1 - 0.04 13.8 1.4 0.058 13.3 0.9 1.3 1 1 0 1 1 1 0 Laminin EGF-like (Domains III and V) FIST_C PF10442.4 KFP01222.1 - 1.5e-10 41.1 0.1 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 FIST C domain PBP_GOBP PF01395.17 KFP01222.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 PBP/GOBP family Toprim_3 PF13362.1 KFP01222.1 - 0.046 13.9 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Toprim domain UQ_con PF00179.21 KFP01223.1 - 4.9e-11 42.2 0.0 6.4e-10 38.6 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP01223.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RNA_pol_Rpb2_4 PF04566.8 KFP01223.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 KIAA1430 PF13879.1 KFP01223.1 - 0.89 10.0 6.7 2.6 8.5 0.2 2.7 3 0 0 3 3 3 0 KIAA1430 homologue Neur_chan_memb PF02932.11 KFP01224.1 - 4.9e-73 245.9 15.7 9.4e-51 172.9 9.7 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP01224.1 - 1e-69 234.0 1.3 1.5e-69 233.4 0.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain DUF2417 PF10329.4 KFP01224.1 - 0.0025 17.2 2.8 0.0027 17.1 1.1 1.7 2 0 0 2 2 2 1 Region of unknown function (DUF2417) DUF1286 PF06939.6 KFP01224.1 - 0.033 14.3 1.3 7.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) Neur_chan_memb PF02932.11 KFP01225.1 - 1.7e-80 270.3 12.2 9.8e-79 264.5 8.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP01225.1 - 2.5e-73 245.8 1.3 4.1e-73 245.1 0.9 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 KFP01226.1 - 1e-71 240.5 0.7 1.4e-71 240.1 0.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP01226.1 - 3.4e-60 203.8 12.1 7.2e-47 160.2 5.9 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Proteasome PF00227.21 KFP01227.1 - 6.8e-50 168.9 0.0 9.9e-50 168.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFP01227.1 - 1.1e-14 53.4 0.2 1.9e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Phenol_monoox PF04663.7 KFP01227.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Phenol hydroxylase conserved region APH PF01636.18 KFP01228.1 - 2e-20 73.5 0.0 2.6e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFP01228.1 - 0.0076 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Aconitase PF00330.15 KFP01229.1 - 1.1e-117 393.3 0.0 1.4e-117 393.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFP01229.1 - 6.9e-38 129.7 0.0 1.2e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Actin PF00022.14 KFP01230.1 - 4.4e-84 282.1 0.0 1.1e-83 280.8 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFP01230.1 - 0.00012 20.8 0.0 0.19 10.2 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein EamA PF00892.15 KFP01231.1 - 5.7e-10 39.3 36.2 7.1e-07 29.3 3.6 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFP01231.1 - 0.00071 19.7 2.6 0.00071 19.7 1.8 3.7 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF2637 PF10935.3 KFP01231.1 - 0.053 13.4 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2637) Cytochrom_B_C PF00032.12 KFP01231.1 - 4.4 7.5 19.1 0.3 11.3 0.3 4.3 3 1 1 4 4 4 0 Cytochrome b(C-terminal)/b6/petD 7tm_1 PF00001.16 KFP01232.1 - 7.1e-36 123.6 6.6 7.1e-36 123.6 4.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) NCKAP5 PF15246.1 KFP01234.1 - 1.9e-116 388.8 22.2 1.9e-116 388.8 15.4 4.6 5 0 0 5 5 5 1 Nck-associated protein 5, Peripheral clock protein APG6 PF04111.7 KFP01235.1 - 0.089 11.8 9.3 0.11 11.5 6.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 5_nucleotid PF05761.9 KFP01235.1 - 0.12 10.8 4.2 0.14 10.6 2.9 1.0 1 0 0 1 1 1 0 5' nucleotidase family PilJ PF13675.1 KFP01235.1 - 0.18 12.1 3.7 0.17 12.1 2.0 1.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term FTO_CTD PF12934.2 KFP01235.1 - 0.27 10.8 7.1 7.7 6.0 0.0 2.0 1 1 1 2 2 2 0 FTO C-terminal domain Sds3 PF08598.6 KFP01235.1 - 0.88 9.0 9.9 1.2 8.5 6.9 1.1 1 0 0 1 1 1 0 Sds3-like Atg14 PF10186.4 KFP01235.1 - 1.9 7.3 6.5 2.3 7.1 4.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 KFP01235.1 - 3.3 7.2 7.2 3.6 7.0 0.8 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG2 PF06148.6 KFP01235.1 - 4.5 7.1 6.3 3.9 7.3 0.5 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 KFP01235.1 - 4.6 7.6 8.3 19 5.6 5.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Glyco_transf_18 PF15024.1 KFP01236.1 - 1.1e-257 855.9 0.6 1.4e-257 855.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 DUF4525 PF15027.1 KFP01236.1 - 1.1e-67 225.7 0.2 2e-67 224.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) Cation_efflux PF01545.16 KFP01237.1 - 0.001 18.2 26.5 0.0032 16.5 18.3 1.7 1 1 0 1 1 1 1 Cation efflux family Orbi_NS3 PF01616.11 KFP01237.1 - 0.12 11.3 1.6 8.4 5.3 0.0 2.3 2 0 0 2 2 2 0 Orbivirus NS3 DUF1385 PF07136.6 KFP01237.1 - 0.66 8.9 5.7 3.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) DUF308 PF03729.8 KFP01237.1 - 2.7 8.0 18.3 10 6.2 0.0 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF3040 PF11239.3 KFP01237.1 - 5.2 7.1 13.3 14 5.7 0.7 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) E1-E2_ATPase PF00122.15 KFP01237.1 - 8.2 5.3 6.8 5.8 5.8 0.2 2.2 2 0 0 2 2 2 0 E1-E2 ATPase Yae1_N PF09811.4 KFP01238.1 - 8.4e-14 50.8 39.8 1.1e+03 -0.8 27.6 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Amidohydro_2 PF04909.9 KFP01239.1 - 3e-54 184.4 0.0 3.4e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Cyclin_N PF00134.18 KFP01240.1 - 4.6e-16 58.5 1.3 7.6e-13 48.1 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP01240.1 - 0.09 12.7 11.0 0.37 10.7 0.1 3.7 3 0 0 3 3 3 0 Cyclin, C-terminal domain Pkinase PF00069.20 KFP01241.1 - 3e-55 187.1 0.0 3.4e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01241.1 - 2.4e-37 128.4 0.0 2.8e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP01241.1 - 1.6e-05 24.0 0.0 3.1e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFP01241.1 - 0.0014 18.4 0.1 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFP01241.1 - 0.075 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Rab3-GTPase_cat PF13890.1 KFP01242.1 - 2.4e-66 222.1 0.0 3.1e-65 218.5 0.0 2.4 3 0 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit Stk19 PF10494.4 KFP01242.1 - 0.23 10.8 0.1 0.35 10.2 0.1 1.2 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 R3H PF01424.17 KFP01243.1 - 6.9e-14 51.2 0.0 1.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 KFP01243.1 - 4.9e-11 42.9 6.8 4.9e-11 42.9 4.7 4.1 4 0 0 4 4 4 1 SUZ domain TUSC2 PF15000.1 KFP01243.1 - 0.015 15.3 0.4 0.096 12.7 0.2 2.5 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Transposase_20 PF02371.11 KFP01243.1 - 0.36 10.9 1.8 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family UBX PF00789.15 KFP01244.1 - 3e-18 65.6 0.0 7.9e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 UBX domain tRNA-synt_2 PF00152.15 KFP01245.1 - 4.2e-80 269.0 0.1 5.5e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFP01245.1 - 1.2e-09 37.9 0.9 2.1e-09 37.0 0.6 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFP01245.1 - 3.4e-05 23.1 0.3 0.29 10.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) S-AdoMet_synt_N PF00438.15 KFP01245.1 - 0.0015 18.6 0.3 0.0095 16.1 0.2 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DUF2130 PF09903.4 KFP01245.1 - 0.057 12.1 0.2 0.31 9.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) 7tm_1 PF00001.16 KFP01246.1 - 2.5e-57 193.9 14.7 3e-57 193.7 10.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CXCR4_N PF12109.3 KFP01246.1 - 2e-19 69.0 6.5 3.1e-19 68.4 4.5 1.3 1 0 0 1 1 1 1 CXCR4 Chemokine receptor N terminal 7TM_GPCR_Srsx PF10320.4 KFP01246.1 - 0.00066 18.9 12.4 0.00097 18.3 8.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFP01246.1 - 0.12 12.1 10.9 0.016 14.9 2.5 2.7 1 1 1 2 2 2 0 Olfactory receptor CitMHS PF03600.11 KFP01246.1 - 0.5 8.8 8.4 0.31 9.5 0.8 2.1 2 0 0 2 2 2 0 Citrate transporter Methyltransf_23 PF13489.1 KFP01247.1 - 4.5e-13 49.2 0.0 8.6e-13 48.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP01247.1 - 4.4e-07 30.2 0.0 8.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP01247.1 - 0.0069 15.9 0.0 0.02 14.5 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 KFP01247.1 - 0.032 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) WIF PF02019.13 KFP01247.1 - 0.044 13.2 0.2 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 WIF domain DsrC PF04358.8 KFP01247.1 - 0.056 13.6 0.9 0.11 12.7 0.7 1.4 1 0 0 1 1 1 0 DsrC like protein BTB PF00651.26 KFP01250.1 - 2e-34 117.8 0.9 2.3e-33 114.4 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.21 KFP01250.1 - 1.1e-09 38.5 0.3 3e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 MATH domain BACK PF07707.10 KFP01250.1 - 0.15 11.9 1.6 12 5.8 0.0 3.5 4 0 0 4 4 4 0 BTB And C-terminal Kelch Neurexophilin PF06312.7 KFP01251.1 - 8.3e-111 368.4 5.4 9.1e-111 368.3 3.8 1.0 1 0 0 1 1 1 1 Neurexophilin Nepo_coat_C PF03688.9 KFP01251.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain EGF_2 PF07974.8 KFP01252.1 - 1.4e-18 66.7 63.6 6.2e-06 26.2 6.0 4.2 4 0 0 4 4 4 4 EGF-like domain EGF PF00008.22 KFP01252.1 - 2.6e-16 59.2 58.1 0.00018 21.3 6.3 4.4 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.2 KFP01252.1 - 3.7e-05 23.5 14.3 0.0021 17.9 2.6 6.2 7 0 0 7 7 7 4 Human growth factor-like EGF Laminin_EGF PF00053.19 KFP01252.1 - 0.083 12.8 54.4 2.1 8.3 4.8 4.2 1 1 3 4 4 4 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 KFP01253.1 - 1.9e-07 30.9 22.2 7.1e-05 22.6 4.2 4.3 4 0 0 4 4 4 2 EGF-like domain EGF_2 PF07974.8 KFP01253.1 - 0.013 15.5 3.4 0.013 15.5 2.4 5.0 3 2 1 4 4 4 0 EGF-like domain UPF0444 PF15475.1 KFP01254.1 - 0.042 13.8 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 HDV_ag PF01517.13 KFP01254.1 - 0.11 12.1 0.2 0.13 11.9 0.2 1.0 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen TMEM154 PF15102.1 KFP01256.1 - 0.00053 19.7 0.1 0.00062 19.5 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.3 KFP01256.1 - 0.0021 17.6 0.1 0.0029 17.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF1560 PF07597.6 KFP01256.1 - 0.0055 16.6 0.1 0.0055 16.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1560) DUF4448 PF14610.1 KFP01256.1 - 0.013 14.9 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.10 KFP01256.1 - 0.074 12.6 1.1 0.11 12.0 0.8 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Chordopox_A33R PF05966.7 KFP01256.1 - 0.074 11.8 0.1 0.083 11.6 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Shisa PF13908.1 KFP01256.1 - 0.1 12.7 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KFP01256.1 - 0.11 10.7 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MLANA PF14991.1 KFP01256.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A SKG6 PF08693.5 KFP01256.1 - 7.1 6.0 7.0 24 4.3 4.9 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Ldl_recept_b PF00058.12 KFP01257.1 - 2e-29 101.6 5.7 3e-11 43.4 0.0 4.1 4 0 0 4 4 4 3 Low-density lipoprotein receptor repeat class B SGL PF08450.7 KFP01257.1 - 8.2e-06 25.3 0.0 4.2e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KFP01257.1 - 0.082 12.8 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Arylesterase Ldl_recept_b PF00058.12 KFP01258.1 - 2.1e-14 53.5 0.1 1.2e-05 25.4 0.0 2.7 3 0 0 3 3 3 2 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFP01258.1 - 6.4e-09 35.7 5.4 1.5e-08 34.6 3.7 1.7 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP01258.1 - 0.00024 20.6 2.7 0.00053 19.5 1.9 1.6 1 0 0 1 1 1 1 Complement Clr-like EGF-like Aminotran_5 PF00266.14 KFP01259.1 - 2.5e-16 59.4 0.0 3.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V RhoGAP PF00620.22 KFP01260.1 - 7.8e-52 174.9 0.8 8.7e-51 171.5 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain DUF3524 PF12038.3 KFP01261.1 - 1.1e-65 220.2 0.2 1.8e-65 219.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glyco_trans_1_4 PF13692.1 KFP01261.1 - 2.5e-08 34.1 0.0 5.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KFP01261.1 - 1.1e-06 28.1 0.0 2.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFP01261.1 - 0.14 12.4 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 zf-H2C2_2 PF13465.1 KFP01262.1 - 1.2e-35 120.0 61.8 1.3e-08 34.6 3.7 8.7 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFP01262.1 - 2.4e-24 84.1 78.7 0.00033 20.7 3.4 8.7 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP01262.1 - 9.5e-16 56.9 63.1 0.00022 21.3 0.9 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP01262.1 - 2.6e-11 43.2 54.8 0.0016 18.4 0.9 8.6 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP01262.1 - 6.1e-08 32.6 54.3 0.016 15.4 0.3 8.5 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP01262.1 - 7.1e-08 32.4 2.0 7.1e-08 32.4 1.4 4.5 4 1 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding Homeobox PF00046.24 KFP01262.1 - 4.4e-05 23.0 0.0 0.00032 20.2 0.0 2.5 2 0 0 2 2 2 1 Homeobox domain zf-C2H2_6 PF13912.1 KFP01262.1 - 0.0046 16.8 61.7 0.0084 15.9 0.6 8.5 8 0 0 8 8 8 3 C2H2-type zinc finger I-set PF07679.11 KFP01263.1 - 5.5e-26 90.2 4.6 6.9e-10 38.6 0.1 4.7 4 1 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP01263.1 - 2.6e-25 88.3 3.8 3.7e-14 52.6 0.1 4.3 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 KFP01263.1 - 4.4e-19 68.7 7.6 1.6e-10 41.2 0.3 4.3 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.12 KFP01263.1 - 7.7e-13 48.3 4.4 0.0041 17.0 0.0 5.4 3 2 1 4 4 4 4 Immunoglobulin V-set domain ig PF00047.20 KFP01263.1 - 3.5e-10 39.8 3.0 6.9e-06 26.1 0.3 4.3 4 0 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.7 KFP01263.1 - 0.0031 17.3 1.5 0.37 10.7 0.0 2.9 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain MLANA PF14991.1 KFP01263.1 - 0.078 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Sushi PF00084.15 KFP01263.1 - 1.4 9.3 5.1 24 5.3 0.0 4.1 4 1 0 4 4 4 0 Sushi domain (SCR repeat) DUF11 PF01345.13 KFP01263.1 - 9 6.4 9.0 1 9.4 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function DUF11 Endosulfine PF04667.12 KFP01266.1 - 3.8e-15 55.6 0.9 4.2e-15 55.4 0.6 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region MAS20 PF02064.10 KFP01266.1 - 0.08 12.8 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor GPP34 PF05719.6 KFP01267.1 - 1.3e-39 136.3 2.0 2.1e-38 132.4 1.4 2.0 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) HORMA PF02301.13 KFP01268.1 - 5.7e-46 156.6 0.0 1.1e-45 155.7 0.0 1.4 1 1 0 1 1 1 1 HORMA domain DUF2756 PF10956.3 KFP01270.1 - 0.094 12.9 2.9 0.7 10.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) C2 PF00168.25 KFP01271.1 - 7.2e-46 153.9 0.2 2.6e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 KFP01271.1 - 0.00099 18.6 0.0 0.33 10.4 0.0 2.8 2 1 0 2 2 2 2 CEP76 C2 domain PTEN_C2 PF10409.4 KFP01271.1 - 0.059 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein YjeF_N PF03853.10 KFP01272.1 - 1.4e-32 112.5 0.0 1.7e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus RasGAP PF00616.14 KFP01273.1 - 1.2e-45 155.6 0.0 3.6e-45 154.0 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KFP01273.1 - 5.1e-34 116.9 6.4 5.1e-34 116.9 4.4 2.2 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.22 KFP01273.1 - 2.8e-19 66.8 14.9 1.7e-06 27.1 0.7 5.2 4 0 0 4 4 4 4 IQ calmodulin-binding motif CH PF00307.26 KFP01273.1 - 7.3e-14 51.7 0.0 2.8e-13 49.8 0.0 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP01273.1 - 0.0061 16.1 0.0 0.025 14.2 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain SHD1 PF03983.7 KFP01273.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 SRF-TF PF00319.13 KFP01276.1 - 9.2e-19 66.4 0.2 1.5e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HJURP_C PF12347.3 KFP01276.1 - 9.9e-10 37.8 0.0 8.6e-08 31.6 0.0 2.9 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat GLTT PF01744.15 KFP01276.1 - 0.14 11.6 5.0 6.3 6.3 0.1 3.1 2 1 0 2 2 2 0 GLTT repeat (6 copies) zf-H2C2_2 PF13465.1 KFP01277.1 - 3.4e-15 55.4 8.3 2.1e-07 30.9 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP01277.1 - 7.9e-09 35.3 13.5 0.00011 22.3 0.7 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP01277.1 - 2e-06 27.7 14.8 0.00013 22.0 0.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP01277.1 - 2.8e-05 23.8 0.9 0.00029 20.6 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP01277.1 - 0.00034 20.6 0.3 0.0033 17.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP01277.1 - 0.00066 19.7 2.1 0.0014 18.8 0.1 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type UNC119_bdg PF15435.1 KFP01278.1 - 4e-94 313.4 1.0 4.5e-94 313.3 0.7 1.0 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue Filament PF00038.16 KFP01280.1 - 2.4e-110 368.8 21.8 2.7e-110 368.6 15.1 1.0 1 0 0 1 1 1 1 Intermediate filament protein Tropomyosin_1 PF12718.2 KFP01280.1 - 0.00013 21.8 24.5 0.00039 20.2 4.7 3.5 3 1 0 3 3 3 1 Tropomyosin like TPR_MLP1_2 PF07926.7 KFP01280.1 - 0.00031 20.4 28.1 0.0032 17.2 1.6 3.8 2 1 2 4 4 4 3 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 KFP01280.1 - 0.0014 17.1 11.4 0.0014 17.1 7.9 2.0 2 1 0 2 2 2 1 AAA domain ATG16 PF08614.6 KFP01280.1 - 0.0048 16.7 16.5 0.14 12.0 1.1 2.5 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) DUF4494 PF14902.1 KFP01280.1 - 0.0087 15.6 1.3 0.058 12.9 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4494) COG2 PF06148.6 KFP01280.1 - 0.089 12.6 18.6 0.14 12.0 0.3 4.6 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 KFP01280.1 - 0.1 12.1 28.9 15 5.0 0.8 3.6 2 1 0 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 KFP01280.1 - 0.12 11.4 6.9 8.1 5.5 0.8 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 KFP01280.1 - 0.2 11.1 20.9 0.053 13.0 2.3 3.8 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 KFP01280.1 - 0.29 9.7 24.2 0.076 11.6 2.8 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.7 KFP01280.1 - 0.31 11.2 15.0 0.23 11.7 1.0 4.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.16 KFP01280.1 - 0.34 10.9 0.1 0.34 10.9 0.0 4.2 4 1 0 4 4 4 0 bZIP transcription factor Baculo_PEP_C PF04513.7 KFP01280.1 - 0.45 10.3 11.5 0.57 10.0 1.3 4.1 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 KFP01280.1 - 0.56 10.6 13.5 1 9.7 1.7 4.5 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) PP_kinase_N PF13089.1 KFP01280.1 - 0.76 9.8 0.0 0.76 9.8 0.0 3.5 3 1 0 3 3 3 0 Polyphosphate kinase N-terminal domain DASH_Duo1 PF08651.5 KFP01280.1 - 1.7 8.2 9.2 0.4 10.2 0.2 3.6 5 0 0 5 5 4 0 DASH complex subunit Duo1 FliJ PF02050.11 KFP01280.1 - 2.1 8.4 21.7 2.4 8.2 0.1 4.3 3 1 1 4 4 4 0 Flagellar FliJ protein COG5 PF10392.4 KFP01280.1 - 2.3 8.1 8.5 0.23 11.4 0.3 3.0 3 1 1 4 4 3 0 Golgi transport complex subunit 5 SRP1_TIP1 PF00660.12 KFP01280.1 - 2.4 8.0 5.2 20 5.0 0.1 3.1 4 0 0 4 4 3 0 Seripauperin and TIP1 family Zein-binding PF04576.10 KFP01280.1 - 2.9 8.0 18.0 0.11 12.6 0.4 3.7 4 1 1 5 5 4 0 Zein-binding CENP-F_leu_zip PF10473.4 KFP01280.1 - 3.7 7.4 25.7 1.7 8.5 4.1 3.9 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 KFP01280.1 - 4 7.2 17.7 3.9 7.2 0.4 4.4 2 1 0 4 4 4 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 KFP01280.1 - 4.4 7.0 19.3 0.21 11.2 0.2 4.6 4 2 1 5 5 5 0 Spc24 subunit of Ndc80 FliD_N PF02465.13 KFP01280.1 - 5.9 7.3 10.4 3.5 8.0 0.2 4.0 3 2 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.5 KFP01280.1 - 7.4 6.6 19.8 0.31 11.1 0.8 3.4 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 KFP01280.1 - 7.7 6.5 11.8 6.9 6.6 0.3 5.1 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) BRE1 PF08647.6 KFP01280.1 - 8.8 6.3 23.4 0.1 12.5 1.3 4.7 3 2 2 5 5 5 0 BRE1 E3 ubiquitin ligase Filament PF00038.16 KFP01281.1 - 4.1e-103 345.1 43.5 4.8e-103 344.9 30.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFP01281.1 - 4.1e-06 24.8 33.6 4.1e-06 24.8 23.3 2.2 1 1 1 2 2 2 1 Myosin tail TPR_MLP1_2 PF07926.7 KFP01281.1 - 1.1e-05 25.2 41.5 0.0012 18.6 3.5 3.6 3 1 1 4 4 4 3 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFP01281.1 - 0.0015 17.8 6.3 0.26 10.4 0.4 3.3 1 1 1 3 3 3 2 Reovirus sigma C capsid protein ATG16 PF08614.6 KFP01281.1 - 0.0071 16.1 35.0 0.12 12.1 12.4 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 KFP01281.1 - 0.015 15.4 5.9 0.015 15.4 4.1 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 KFP01281.1 - 0.025 14.4 38.3 0.056 13.3 11.2 3.3 3 1 0 3 3 3 0 Tropomyosin like AAA_13 PF13166.1 KFP01281.1 - 0.038 12.4 31.2 0.005 15.3 16.6 2.2 1 1 1 2 2 2 0 AAA domain HALZ PF02183.13 KFP01281.1 - 0.062 13.0 0.4 0.062 13.0 0.3 4.6 5 0 0 5 5 4 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 KFP01281.1 - 0.094 12.5 36.5 0.028 14.2 9.8 3.4 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.8 KFP01281.1 - 0.098 13.0 17.8 1.1 9.6 4.2 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) FUSC PF04632.7 KFP01281.1 - 0.14 10.5 5.6 0.23 9.8 3.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.1 KFP01281.1 - 0.32 11.0 36.3 0.099 12.6 4.7 2.8 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2353 PF09789.4 KFP01281.1 - 0.59 9.3 37.3 3.1 6.9 8.1 3.0 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HOOK PF05622.7 KFP01281.1 - 0.6 7.8 40.7 1 7.1 15.0 2.0 1 1 1 2 2 2 0 HOOK protein WEMBL PF05701.6 KFP01281.1 - 0.91 7.9 34.4 0.27 9.6 21.2 2.0 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.7 KFP01281.1 - 1.1 9.0 22.9 4 7.2 1.0 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 KFP01281.1 - 1.3 7.8 19.4 0.78 8.6 6.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BicD PF09730.4 KFP01281.1 - 5.9 5.1 36.0 2.1 6.5 7.4 2.1 1 1 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Lectin_N PF03954.9 KFP01281.1 - 6.9 6.0 11.3 2.5 7.5 1.3 3.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF972 PF06156.8 KFP01281.1 - 8.5 6.7 40.7 2.8 8.3 2.1 5.1 1 1 3 5 5 5 0 Protein of unknown function (DUF972) Filament PF00038.16 KFP01282.1 - 1.8e-102 343.0 40.0 2.1e-102 342.8 27.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFP01282.1 - 3.4e-06 26.8 35.0 0.0018 18.0 1.7 3.7 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KFP01282.1 - 1.7e-05 22.8 34.6 0.0019 16.0 24.2 2.8 1 1 0 1 1 1 1 Myosin tail Reo_sigmaC PF04582.7 KFP01282.1 - 0.00092 18.4 3.9 1.1 8.3 0.4 3.1 1 1 1 3 3 3 2 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KFP01282.1 - 0.0011 19.1 1.4 0.0011 19.1 1.0 3.5 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 KFP01282.1 - 0.004 17.0 31.4 0.0059 16.4 10.6 3.2 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 KFP01282.1 - 0.007 16.2 29.6 0.2 11.4 11.1 2.5 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 KFP01282.1 - 0.0076 16.1 0.6 0.0076 16.1 0.4 5.1 4 1 1 5 5 5 2 bZIP transcription factor Baculo_PEP_C PF04513.7 KFP01282.1 - 0.013 15.2 14.2 0.2 11.4 1.3 4.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 KFP01282.1 - 0.027 12.9 22.9 0.0091 14.5 13.0 2.0 1 1 0 1 1 1 0 AAA domain HOOK PF05622.7 KFP01282.1 - 0.15 9.8 35.7 0.55 7.9 24.8 1.7 1 1 0 1 1 1 0 HOOK protein IncA PF04156.9 KFP01282.1 - 0.15 11.6 40.9 3.8 7.0 9.5 3.1 1 1 1 2 2 2 0 IncA protein BicD PF09730.4 KFP01282.1 - 0.17 10.1 33.2 0.53 8.5 5.5 2.1 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D CHDCT2 PF08074.6 KFP01282.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.6 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain Spc7 PF08317.6 KFP01282.1 - 0.72 8.4 35.9 0.1 11.2 7.8 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 KFP01282.1 - 0.83 9.8 18.8 3.1 8.0 2.0 4.8 2 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF883 PF05957.8 KFP01282.1 - 1.7 9.1 18.7 3 8.3 4.0 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF972 PF06156.8 KFP01282.1 - 2 8.7 35.2 2.8 8.3 0.7 5.1 1 1 3 5 5 5 0 Protein of unknown function (DUF972) ApoLp-III PF07464.6 KFP01282.1 - 2.3 8.2 20.6 0.62 10.0 4.4 3.4 1 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.6 KFP01282.1 - 2.5 8.0 11.8 0.46 10.3 0.2 4.0 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.7 KFP01282.1 - 2.6 6.3 5.2 3 6.1 3.1 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 KFP01282.1 - 3.7 7.4 35.9 0.52 10.1 11.3 3.1 1 1 2 3 3 3 0 Tropomyosin like DUF342 PF03961.8 KFP01282.1 - 5.1 5.4 28.6 0.99 7.7 3.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Transposase_22 PF02994.9 KFP01282.1 - 6.4 5.1 25.3 0.3 9.5 8.0 2.5 1 1 0 2 2 2 0 L1 transposable element CENP-Q PF13094.1 KFP01282.1 - 6.9 6.6 30.4 2.7 7.9 1.8 3.4 2 2 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin PF00804.20 KFP01282.1 - 8.6 6.5 22.7 2.6 8.2 0.7 3.7 2 2 1 3 3 3 0 Syntaxin Rootletin PF15035.1 KFP01282.1 - 8.7 6.2 33.4 27 4.6 9.0 3.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Filament PF00038.16 KFP01283.1 - 1.3e-102 343.4 40.2 1.5e-102 343.2 27.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFP01283.1 - 1e-05 25.2 35.6 0.0019 17.9 1.3 3.7 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KFP01283.1 - 4.4e-05 21.4 33.1 7.5e-05 20.6 20.4 2.3 1 1 1 2 2 2 1 Myosin tail Reo_sigmaC PF04582.7 KFP01283.1 - 0.00064 19.0 2.9 2.2 7.3 0.2 3.1 1 1 1 3 3 3 2 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KFP01283.1 - 0.0027 17.8 1.5 0.0027 17.8 1.0 3.4 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family ATG16 PF08614.6 KFP01283.1 - 0.0077 16.0 28.3 0.26 11.0 11.1 2.5 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 KFP01283.1 - 0.009 15.8 15.6 0.009 15.8 10.8 3.3 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 KFP01283.1 - 0.0094 15.8 0.6 0.0094 15.8 0.4 5.0 4 1 1 5 5 5 2 bZIP transcription factor Baculo_PEP_C PF04513.7 KFP01283.1 - 0.011 15.5 12.2 0.21 11.3 1.3 4.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 KFP01283.1 - 0.029 12.8 21.3 0.015 13.7 12.6 1.9 1 1 0 1 1 1 0 AAA domain ADIP PF11559.3 KFP01283.1 - 0.085 12.7 29.3 0.061 13.2 9.4 3.1 2 2 0 2 2 2 0 Afadin- and alpha -actinin-Binding HOOK PF05622.7 KFP01283.1 - 0.65 7.7 35.1 3.4 5.3 24.3 1.8 1 1 0 1 1 1 0 HOOK protein BicD PF09730.4 KFP01283.1 - 0.76 8.0 32.8 0.97 7.7 4.6 2.1 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D DUF972 PF06156.8 KFP01283.1 - 0.83 10.0 33.4 2.9 8.2 1.4 5.1 1 1 3 5 5 5 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 KFP01283.1 - 1.1 9.4 17.7 3.4 7.8 1.9 4.6 2 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF883 PF05957.8 KFP01283.1 - 1.2 9.5 17.2 3.8 7.9 4.0 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) FUSC PF04632.7 KFP01283.1 - 2.2 6.5 4.4 4 5.7 3.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family WEMBL PF05701.6 KFP01283.1 - 2.7 6.3 29.9 2.9 6.2 19.6 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ApoLp-III PF07464.6 KFP01283.1 - 2.7 7.9 19.2 0.71 9.8 4.2 3.2 2 2 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.6 KFP01283.1 - 3.2 7.6 10.6 0.58 10.0 0.2 3.6 5 0 0 5 5 4 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 KFP01283.1 - 3.5 5.9 26.8 0.65 8.3 2.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Tropomyosin_1 PF12718.2 KFP01283.1 - 4.7 7.0 35.4 0.65 9.8 11.3 3.2 1 1 2 3 3 3 0 Tropomyosin like Transposase_22 PF02994.9 KFP01283.1 - 9.5 4.6 24.9 0.47 8.8 8.2 2.4 1 1 2 3 3 3 0 L1 transposable element CALCOCO1 PF07888.6 KFP01283.1 - 10 4.3 34.6 21 3.2 24.0 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.16 KFP01284.1 - 6.3e-81 272.2 46.2 7.4e-81 272.0 32.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 KFP01284.1 - 1.7 8.1 46.4 0.09 12.3 11.2 3.3 2 1 1 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 KFP01284.1 - 4.7 7.6 24.4 2 8.8 2.0 4.3 2 2 2 4 4 4 0 Syntaxin 6, N-terminal WXG100 PF06013.7 KFP01284.1 - 5.6 7.0 19.5 1.1 9.3 2.2 4.0 2 2 1 3 3 3 0 Proteins of 100 residues with WXG VSG_B PF13206.1 KFP01284.1 - 6.1 5.8 10.2 6.2 5.8 0.2 2.9 2 1 1 3 3 3 0 Trypanosomal VSG domain DUF643 PF04867.7 KFP01284.1 - 6.7 7.1 8.5 1.1 9.7 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF643) Filament PF00038.16 KFP01285.1 - 5.6e-84 282.2 29.2 6.3e-84 282.0 20.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein PMG PF05287.7 KFP01285.1 - 0.015 15.1 1.4 0.037 13.8 1.0 1.7 1 0 0 1 1 1 0 PMG protein TPR_MLP1_2 PF07926.7 KFP01285.1 - 0.048 13.3 20.2 0.041 13.6 0.8 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein zf-C2HC_2 PF13913.1 KFP01285.1 - 0.056 13.1 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FlaC_arch PF05377.6 KFP01285.1 - 0.11 12.4 2.1 0.31 10.9 0.2 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KFP01285.1 - 0.21 11.3 1.2 1 9.1 0.5 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2205 PF10224.4 KFP01285.1 - 0.44 10.1 6.9 6.4 6.4 0.0 3.9 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF4407 PF14362.1 KFP01285.1 - 0.92 8.4 4.0 1.5 7.6 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AKNA PF12443.3 KFP01285.1 - 1.9 8.5 9.2 0.23 11.5 1.9 2.6 1 1 2 3 3 3 0 AT-hook-containing transcription factor Filament PF00038.16 KFP01286.1 - 5.1e-89 298.8 26.5 5.8e-89 298.6 18.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 KFP01286.1 - 0.00026 20.8 7.1 0.00026 20.8 4.9 3.1 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFP01286.1 - 0.023 13.8 1.6 0.11 11.6 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 KFP01286.1 - 0.16 11.7 16.8 0.11 12.3 4.4 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.7 KFP01286.1 - 0.64 10.2 5.5 0.32 11.1 1.4 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2205 PF10224.4 KFP01286.1 - 3.1 7.4 11.5 3.2 7.3 0.2 3.7 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) Sporozoite_P67 PF05642.6 KFP01286.1 - 3.2 5.4 7.5 4.6 4.9 5.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1664 PF07889.7 KFP01286.1 - 3.8 7.3 8.7 2.2 8.0 0.3 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) FliJ PF02050.11 KFP01286.1 - 4.2 7.4 20.5 0.038 14.0 2.3 3.3 4 0 0 4 4 4 0 Flagellar FliJ protein IATP PF04568.7 KFP01286.1 - 5.3 7.1 10.4 15 5.7 0.2 3.9 3 1 1 4 4 4 0 Mitochondrial ATPase inhibitor, IATP TPR_MLP1_2 PF07926.7 KFP01286.1 - 6.3 6.5 23.0 0.72 9.5 0.4 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFP01286.1 - 8.5 5.9 31.1 0.041 13.4 5.9 3.0 2 1 1 3 3 3 0 IncA protein AKNA PF12443.3 KFP01286.1 - 8.8 6.4 10.1 0.53 10.3 1.9 2.7 2 1 0 2 2 2 0 AT-hook-containing transcription factor Filament PF00038.16 KFP01287.1 - 3.9e-110 368.1 31.8 4.5e-110 367.9 22.0 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFP01287.1 - 0.00037 20.2 1.5 0.00037 20.2 1.1 3.7 3 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFP01287.1 - 0.002 17.7 25.3 0.048 13.2 4.6 3.4 2 1 1 3 3 3 2 IncA protein Phage_GP20 PF06810.6 KFP01287.1 - 0.0021 17.5 3.0 0.0021 17.5 2.1 3.6 2 1 2 4 4 4 1 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.4 KFP01287.1 - 0.005 16.7 21.8 0.034 13.9 3.6 3.1 2 2 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.4 KFP01287.1 - 0.0055 16.6 1.1 0.017 15.1 0.5 2.0 1 1 0 1 1 1 1 Golgi transport complex subunit 5 ATG16 PF08614.6 KFP01287.1 - 0.0057 16.5 25.0 0.038 13.8 5.8 3.0 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) ADIP PF11559.3 KFP01287.1 - 0.04 13.8 22.4 0.056 13.3 1.4 3.7 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 KFP01287.1 - 0.092 12.7 14.8 0.51 10.3 0.3 4.8 4 1 0 4 4 4 0 bZIP transcription factor Myosin_tail_1 PF01576.14 KFP01287.1 - 0.12 10.0 31.9 0.013 13.3 3.2 2.6 1 1 0 3 3 3 0 Myosin tail Tropomyosin_1 PF12718.2 KFP01287.1 - 0.33 10.7 27.3 0.064 13.0 5.7 2.9 2 1 1 3 3 3 0 Tropomyosin like Baculo_PEP_C PF04513.7 KFP01287.1 - 0.51 10.1 18.7 0.061 13.1 0.3 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KFP01287.1 - 1 8.4 6.5 8.9 5.3 0.5 2.7 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DUF883 PF05957.8 KFP01287.1 - 1.2 9.5 12.3 3 8.2 1.6 4.2 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Tup_N PF08581.5 KFP01287.1 - 1.7 8.8 16.1 7.8 6.7 0.4 5.0 4 2 1 5 5 5 0 Tup N-terminal Fib_alpha PF08702.5 KFP01287.1 - 3.7 7.6 18.5 0.7 10.0 0.6 3.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 KFP01287.1 - 6.7 6.6 6.8 21 5.0 0.2 3.8 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Filament PF00038.16 KFP01288.1 - 1.3e-111 372.9 34.0 1.6e-111 372.7 23.6 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFP01288.1 - 0.0003 20.5 30.5 0.0012 18.5 0.4 3.7 3 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KFP01288.1 - 0.0016 16.3 3.0 0.0016 16.3 2.1 2.5 1 1 0 2 2 2 2 Myosin tail CENP-F_leu_zip PF10473.4 KFP01288.1 - 0.0049 16.7 26.8 0.016 15.0 6.0 3.7 1 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 KFP01288.1 - 0.012 15.4 0.5 0.012 15.4 0.4 4.4 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 KFP01288.1 - 0.013 14.0 20.1 0.0026 16.3 10.8 2.0 1 1 0 1 1 1 0 AAA domain ADIP PF11559.3 KFP01288.1 - 0.019 14.8 23.8 0.093 12.6 1.3 3.5 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KFP01288.1 - 0.038 13.1 6.8 0.26 10.4 0.7 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DED PF01335.16 KFP01288.1 - 0.038 14.1 2.9 1.1 9.4 0.0 3.2 3 0 0 3 3 3 0 Death effector domain bZIP_1 PF00170.16 KFP01288.1 - 0.039 13.9 0.1 0.039 13.9 0.1 4.6 5 1 0 5 5 5 0 bZIP transcription factor Tropomyosin_1 PF12718.2 KFP01288.1 - 0.05 13.4 27.9 0.21 11.4 8.2 3.5 2 1 2 4 4 4 0 Tropomyosin like Fib_alpha PF08702.5 KFP01288.1 - 0.085 12.9 17.9 0.2 11.7 0.2 3.6 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Hemerythrin PF01814.18 KFP01288.1 - 0.094 12.8 4.9 3.7 7.7 0.0 2.8 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain IncA PF04156.9 KFP01288.1 - 0.12 12.0 28.0 0.076 12.6 6.2 3.3 2 1 1 3 3 3 0 IncA protein ACCA PF03255.9 KFP01288.1 - 0.21 11.1 13.8 0.51 9.8 1.1 3.3 2 1 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF883 PF05957.8 KFP01288.1 - 0.26 11.7 19.8 0.34 11.3 4.1 4.6 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF2580 PF10824.3 KFP01288.1 - 0.49 10.7 4.5 0.7 10.2 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) Spc7 PF08317.6 KFP01288.1 - 1.2 7.7 28.1 0.06 12.0 6.9 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein ApoLp-III PF07464.6 KFP01288.1 - 1.9 8.4 14.5 0.062 13.3 3.9 2.7 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF342 PF03961.8 KFP01288.1 - 3.8 5.8 18.7 1.7 6.9 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF342) DUF948 PF06103.6 KFP01288.1 - 4.4 7.2 11.4 3.4 7.6 0.7 4.3 3 3 2 5 5 5 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 KFP01288.1 - 5.4 5.9 29.3 0.55 9.2 5.8 3.1 1 1 3 4 4 4 0 Autophagy protein Apg6 FlaC_arch PF05377.6 KFP01288.1 - 9.5 6.2 13.7 4.6 7.2 0.5 4.9 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Filament PF00038.16 KFP01290.1 - 5.8e-108 361.0 35.2 6.8e-108 360.8 24.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein ADIP PF11559.3 KFP01290.1 - 0.00021 21.2 29.9 0.002 18.0 1.9 3.9 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.6 KFP01290.1 - 0.00069 19.0 4.0 0.00069 19.0 2.8 4.0 2 1 1 3 3 3 1 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 KFP01290.1 - 0.00097 19.0 9.4 0.00097 19.0 6.5 3.4 2 1 1 3 3 3 1 Tropomyosin like CENP-F_leu_zip PF10473.4 KFP01290.1 - 0.0018 18.1 5.4 0.0018 18.1 3.7 3.5 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KFP01290.1 - 0.0054 16.4 33.6 0.028 14.1 8.0 3.7 2 2 0 3 3 3 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFP01290.1 - 0.0069 15.6 9.9 0.019 14.1 1.2 2.6 1 1 2 3 3 3 2 Reovirus sigma C capsid protein DUF4407 PF14362.1 KFP01290.1 - 0.67 8.8 18.4 3.3 6.5 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GAS PF13851.1 KFP01290.1 - 0.9 8.6 33.4 0.29 10.3 6.0 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KFP01290.1 - 3 7.9 25.5 0.15 12.1 2.4 3.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TSC22 PF01166.13 KFP01290.1 - 3.6 7.6 17.1 3.1 7.8 0.4 4.6 4 1 1 5 5 5 0 TSC-22/dip/bun family Spc7 PF08317.6 KFP01290.1 - 3.7 6.1 33.7 0.066 11.8 5.5 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF948 PF06103.6 KFP01290.1 - 4.2 7.3 15.6 3 7.7 2.3 4.1 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Tropomyosin PF00261.15 KFP01290.1 - 5.7 5.9 32.3 3.5 6.6 3.2 3.2 1 1 1 3 3 3 0 Tropomyosin AKNA PF12443.3 KFP01290.1 - 8.6 6.4 9.1 1.7 8.7 0.9 3.1 2 1 1 3 3 3 0 AT-hook-containing transcription factor PilJ PF13675.1 KFP01290.1 - 9 6.6 11.7 31 4.9 0.5 3.7 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Rootletin PF15035.1 KFP01290.1 - 9.6 6.1 27.7 3.2 7.6 4.6 2.5 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Filament PF00038.16 KFP01291.1 - 1.2e-115 386.2 37.9 1.4e-115 386.0 26.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFP01291.1 - 0.00034 20.3 37.5 0.002 17.8 2.6 4.0 2 2 2 5 5 5 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KFP01291.1 - 0.00046 18.0 11.9 0.00046 18.0 8.3 2.8 1 1 2 3 3 3 2 Myosin tail CENP-F_leu_zip PF10473.4 KFP01291.1 - 0.00099 18.9 29.0 0.013 15.4 5.6 3.6 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KFP01291.1 - 0.027 13.6 6.7 0.94 8.5 0.2 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DASH_Duo1 PF08651.5 KFP01291.1 - 0.038 13.5 7.2 0.11 12.0 0.3 3.9 3 1 1 4 4 4 0 DASH complex subunit Duo1 ADIP PF11559.3 KFP01291.1 - 0.075 12.9 27.4 0.34 10.8 5.3 3.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KFP01291.1 - 0.16 12.4 24.6 2 8.9 2.2 5.5 3 1 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) DUF2937 PF11157.3 KFP01291.1 - 0.19 11.0 9.4 3.3 6.9 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2937) Baculo_PEP_C PF04513.7 KFP01291.1 - 0.2 11.4 18.7 4.8 7.0 1.0 4.1 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 KFP01291.1 - 0.56 10.0 29.3 0.64 9.8 7.2 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.6 KFP01291.1 - 0.75 9.6 12.9 18 5.2 0.0 4.9 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.8 KFP01291.1 - 1.2 9.5 21.8 4.9 7.6 5.1 4.8 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.1 KFP01291.1 - 1.3 7.3 31.2 0.066 11.6 15.3 2.4 1 1 1 2 2 2 0 AAA domain Fib_alpha PF08702.5 KFP01291.1 - 1.4 9.0 22.2 0.13 12.4 0.6 3.8 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family GAS PF13851.1 KFP01291.1 - 1.9 7.6 35.5 0.51 9.4 8.2 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ACCA PF03255.9 KFP01291.1 - 2.2 7.8 18.6 0.61 9.6 0.7 4.1 1 1 4 5 5 5 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit WXG100 PF06013.7 KFP01291.1 - 4.2 7.4 11.7 3 7.9 3.6 3.7 3 2 0 3 3 3 0 Proteins of 100 residues with WXG FlaC_arch PF05377.6 KFP01291.1 - 6.6 6.7 13.1 63 3.5 0.3 5.6 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 KFP01291.1 - 7.4 5.4 23.6 0.22 10.4 1.3 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KFP01292.1 - 2.6e-75 253.8 32.9 3e-75 253.6 22.8 1.0 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 KFP01292.1 - 0.0073 15.9 6.7 0.0073 15.9 4.7 2.8 1 1 2 3 3 3 2 IncA protein DegS PF05384.6 KFP01292.1 - 0.01 15.0 4.5 0.01 15.0 3.1 4.3 1 1 3 4 4 4 0 Sensor protein DegS DUF972 PF06156.8 KFP01292.1 - 0.038 14.3 1.2 0.038 14.3 0.8 4.6 2 1 2 4 4 4 0 Protein of unknown function (DUF972) NSP2-B_epitope PF14757.1 KFP01292.1 - 0.056 12.9 0.3 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Reo_sigmaC PF04582.7 KFP01292.1 - 0.062 12.4 7.6 1.4 8.0 1.1 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KFP01292.1 - 0.19 11.5 8.4 0.22 11.3 0.3 3.4 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 KFP01292.1 - 0.34 10.9 19.0 0.045 13.7 2.8 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DNA_repr_REX1B PF14966.1 KFP01292.1 - 2.3 8.6 15.7 7.4 7.0 1.4 4.5 3 1 2 5 5 5 0 DNA repair REX1-B TPR_MLP1_2 PF07926.7 KFP01292.1 - 2.6 7.8 32.1 3.5 7.3 5.0 4.7 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein DUF3887 PF13026.1 KFP01292.1 - 2.8 8.2 9.8 0.29 11.4 1.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3887) Bin3 PF06859.7 KFP01293.1 - 1.3e-11 44.4 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.1 KFP01293.1 - 2.2e-06 27.3 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP01293.1 - 4.5e-05 23.8 0.0 0.00011 22.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP01293.1 - 0.0086 16.5 0.0 0.047 14.1 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP01293.1 - 0.021 14.8 0.0 0.08 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KFP01293.1 - 0.024 14.9 1.1 0.09 13.1 0.2 2.1 1 1 1 2 2 2 0 Methyltransferase domain HHH_8 PF14716.1 KFP01293.1 - 0.033 14.3 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain Methyltransf_18 PF12847.2 KFP01293.1 - 0.048 14.2 0.0 0.089 13.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KFP01293.1 - 0.067 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Bax1-I PF01027.15 KFP01294.1 - 1.4e-14 54.1 21.5 1.7e-14 53.9 14.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MIP PF00230.15 KFP01295.1 - 1.4e-79 266.7 9.2 1.7e-79 266.5 6.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3353 PF11833.3 KFP01295.1 - 6.4 6.1 8.7 87 2.4 5.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) MIP PF00230.15 KFP01296.1 - 4.9e-74 248.6 15.4 5.7e-74 248.4 10.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein HCO3_cotransp PF00955.16 KFP01297.1 - 5.6e-68 229.8 4.5 8.1e-68 229.3 3.1 1.2 1 0 0 1 1 1 1 HCO3- transporter family Multi_Drug_Res PF00893.14 KFP01297.1 - 0.058 13.8 0.2 0.058 13.8 0.1 1.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF843 PF05814.6 KFP01297.1 - 0.14 11.9 5.9 0.13 12.0 0.5 2.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Trypsin PF00089.21 KFP01298.1 - 2.9e-69 233.0 3.9 3.2e-69 232.8 2.7 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFP01298.1 - 0.00016 21.6 0.0 0.00047 20.1 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain 7tm_4 PF13853.1 KFP01299.1 - 3e-64 215.1 8.9 3.4e-64 214.9 6.1 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFP01299.1 - 5.1e-06 25.8 4.5 6.2e-06 25.5 3.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_6 PF12697.2 KFP01300.1 - 2.1e-20 73.5 0.0 8.4e-20 71.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP01300.1 - 2.7e-07 30.4 0.1 4.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP01300.1 - 6.3e-06 25.9 0.0 0.08 12.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 KFP01300.1 - 0.0025 17.4 0.1 0.0044 16.6 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KFP01300.1 - 0.0035 16.9 0.0 0.0088 15.6 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 KFP01300.1 - 0.013 14.9 0.3 1.3 8.4 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KFP01300.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 KFP01300.1 - 0.037 13.4 0.2 0.097 12.0 0.2 1.7 1 1 0 1 1 1 0 Putative esterase P4Ha_N PF08336.6 KFP01301.1 - 2.2e-21 76.0 0.0 3.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_2 PF07719.12 KFP01301.1 - 0.0089 15.8 0.1 8.5 6.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP01301.1 - 0.084 12.8 0.0 0.45 10.4 0.0 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFP01301.1 - 0.13 12.7 0.0 2.4 8.8 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SPC25 PF06703.6 KFP01302.1 - 8.5e-51 171.7 0.5 3.4e-50 169.7 0.3 1.7 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) LRR_4 PF12799.2 KFP01303.1 - 1.4e-20 72.4 12.0 7.2e-07 28.6 0.0 4.6 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFP01303.1 - 3.4e-12 45.0 11.8 0.4 10.8 0.0 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.28 KFP01303.1 - 5.6e-12 43.9 12.8 1.4 9.2 0.0 7.6 6 1 1 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 KFP01303.1 - 4.4e-10 38.0 16.5 5.8 7.5 0.1 7.8 7 0 0 7 7 7 6 Leucine rich repeat LRR_8 PF13855.1 KFP01303.1 - 4.4e-10 39.1 15.8 0.00011 21.8 1.5 4.3 2 2 3 5 5 5 5 Leucine rich repeat Peptidase_M43 PF05572.8 KFP01304.1 - 0.06 12.9 0.4 0.056 13.0 0.3 1.1 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A ISK_Channel PF02060.10 KFP01305.1 - 1.8e-06 27.5 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel DUF202 PF02656.10 KFP01305.1 - 0.12 12.6 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Pkinase_Tyr PF07714.12 KFP01306.1 - 1.7e-97 325.5 0.0 1.9e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP01306.1 - 2.5e-48 164.5 0.0 3.1e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFP01306.1 - 1.6e-16 60.4 0.1 2.7e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.9 KFP01306.1 - 0.0077 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP01306.1 - 0.16 10.8 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Laminin_G_1 PF00054.18 KFP01307.1 - 9.9e-31 106.4 0.1 4.4e-25 88.1 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.19 KFP01307.1 - 9.7e-26 90.3 0.1 3.6e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.10 KFP01307.1 - 9.1e-20 70.3 58.3 5.8e-09 35.7 4.9 4.9 4 1 0 4 4 4 4 Calcium-binding EGF domain FXa_inhibition PF14670.1 KFP01307.1 - 1.7e-16 60.0 56.8 9.3e-08 32.0 7.1 4.7 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site Gla PF00594.15 KFP01307.1 - 2.8e-15 55.7 8.9 5.8e-15 54.6 6.1 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain EGF PF00008.22 KFP01307.1 - 1.2e-12 47.5 49.8 0.00022 21.1 4.1 4.7 4 0 0 4 4 4 4 EGF-like domain cEGF PF12662.2 KFP01307.1 - 5e-10 38.8 39.4 6.8e-07 28.8 2.0 5.7 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.2 KFP01307.1 - 6.1e-09 35.6 37.2 0.0018 18.2 4.2 4.6 4 0 0 4 4 4 4 EGF domain hEGF PF12661.2 KFP01307.1 - 0.0007 19.5 16.8 0.022 14.8 2.5 3.8 3 0 0 3 3 3 2 Human growth factor-like EGF Arf PF00025.16 KFP01308.1 - 1.1e-42 145.2 1.7 2e-42 144.4 0.0 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 KFP01308.1 - 1.2e-07 31.2 0.0 2.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP01308.1 - 2.2e-06 27.0 2.3 3.4e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFP01308.1 - 2.6e-05 24.1 0.0 6.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFP01308.1 - 3.5e-05 22.6 0.0 3.5e-05 22.6 0.0 3.5 2 2 1 3 3 3 1 G-protein alpha subunit Miro PF08477.8 KFP01308.1 - 0.00045 20.6 1.0 0.0026 18.2 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KFP01308.1 - 0.026 13.9 0.3 0.056 12.8 0.2 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1395 PF07160.7 KFP01308.1 - 0.17 11.3 13.6 0.041 13.3 6.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) SNARE PF05739.14 KFP01309.1 - 6.9e-14 51.2 2.0 6.9e-14 51.2 1.4 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFP01309.1 - 1.5e-08 34.7 9.0 1.5e-08 34.7 6.2 2.8 3 0 0 3 3 3 1 Syntaxin ALO PF04030.9 KFP01309.1 - 0.061 12.9 0.5 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Fe_bilin_red PF05996.7 KFP01309.1 - 0.083 12.3 2.7 0.071 12.5 0.8 1.6 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase Fib_alpha PF08702.5 KFP01309.1 - 0.93 9.6 23.6 0.1 12.7 4.3 3.6 1 1 0 3 3 3 0 Fibrinogen alpha/beta chain family NAAA-beta PF15508.1 KFP01309.1 - 0.94 9.8 4.0 2.1 8.7 0.3 2.7 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Filo_VP35 PF02097.10 KFP01309.1 - 1.1 8.3 9.0 0.11 11.6 0.9 2.1 1 1 0 2 2 2 0 Filoviridae VP35 Syntaxin-6_N PF09177.6 KFP01309.1 - 2.1 8.8 16.8 0.096 13.0 2.6 3.4 2 2 2 4 4 4 0 Syntaxin 6, N-terminal DASH_Dad3 PF08656.5 KFP01309.1 - 3.2 7.5 14.7 0.69 9.6 0.5 4.1 4 0 0 4 4 4 0 DASH complex subunit Dad3 MbeD_MobD PF04899.7 KFP01309.1 - 3.4 7.6 8.8 3.3 7.6 1.3 3.3 2 1 1 3 3 3 0 MbeD/MobD like Nol1_Nop2_Fmu PF01189.12 KFP01310.1 - 5.4e-23 81.7 0.0 7.5e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KFP01310.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFP01310.1 - 0.0017 18.4 0.0 0.0071 16.3 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KFP01310.1 - 0.02 15.4 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain POR PF01558.13 KFP01310.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Drf_FH1 PF06346.7 KFP01311.1 - 5.5e-05 22.7 117.4 0.18 11.2 32.4 3.0 1 1 2 3 3 3 3 Formin Homology Region 1 Drf_FH1 PF06346.7 KFP01312.1 - 5.5e-05 22.7 117.4 0.18 11.2 32.4 3.0 1 1 2 3 3 3 3 Formin Homology Region 1 Pkinase_Tyr PF07714.12 KFP01313.1 - 1.6e-64 217.4 0.0 1.8e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP01313.1 - 9.2e-27 93.8 0.0 1.1e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KFP01313.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Arf PF00025.16 KFP01314.1 - 2e-54 183.4 0.0 2.3e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFP01314.1 - 1.2e-12 47.3 2.2 6e-08 31.7 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFP01314.1 - 7.2e-11 41.7 0.0 8.5e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP01314.1 - 1.9e-10 40.2 0.1 2.5e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFP01314.1 - 1.2e-08 34.9 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP01314.1 - 3.2e-07 29.7 0.1 3.7e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFP01314.1 - 4.6e-05 23.8 0.0 7.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFP01314.1 - 0.00055 19.4 0.0 0.016 14.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KFP01314.1 - 0.0087 16.3 0.0 0.021 15.1 0.0 1.6 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 KFP01314.1 - 0.016 14.4 0.2 0.035 13.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 KFP01314.1 - 0.033 14.3 0.1 0.26 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFP01314.1 - 0.12 11.8 0.1 2.7 7.4 0.0 2.1 1 1 0 2 2 2 0 FtsK/SpoIIIE family Cupin_4 PF08007.7 KFP01316.1 - 2.9e-91 306.0 0.0 3.8e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 KFP01316.1 - 1.2e-06 28.1 0.2 0.00017 21.1 0.1 2.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 KFP01316.1 - 0.00061 19.2 0.1 0.011 15.2 0.1 2.2 1 1 0 1 1 1 1 Cupin domain T2SF PF00482.18 KFP01316.1 - 0.01 15.7 0.4 0.023 14.6 0.1 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F AraC_binding PF02311.14 KFP01316.1 - 0.057 13.1 0.1 0.25 11.0 0.0 2.1 2 1 0 2 2 2 0 AraC-like ligand binding domain MPC PF03650.8 KFP01317.1 - 2.6e-35 120.9 0.4 2.7e-35 120.9 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) V-set PF07686.12 KFP01318.1 - 7e-19 67.8 0.0 1.2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP01318.1 - 7.2e-05 22.5 0.1 0.0003 20.5 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP01318.1 - 0.0012 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Myelin-PO_C PF10570.4 KFP01318.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Myelin-PO cytoplasmic C-term p65 binding region ig PF00047.20 KFP01318.1 - 0.0046 17.0 0.5 0.052 13.6 0.4 2.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP01318.1 - 0.0087 16.5 1.7 0.11 13.0 0.2 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Herpes_gE PF02480.11 KFP01318.1 - 0.026 12.7 0.0 0.67 8.1 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Yae1_N PF09811.4 KFP01320.1 - 3.2e-10 39.3 28.9 2.8 7.5 20.1 3.8 1 1 0 1 1 1 1 Essential protein Yae1, N terminal MMtag PF10159.4 KFP01321.1 - 2.9e-32 110.5 1.4 2.9e-32 110.5 1.0 1.7 2 0 0 2 2 2 1 Kinase phosphorylation protein Guanylate_kin PF00625.16 KFP01322.1 - 1.1e-69 233.5 0.0 1.2e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KFP01322.1 - 9e-07 29.2 0.0 1.6e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP01322.1 - 4.7e-06 26.7 0.3 1.4e-05 25.1 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KFP01322.1 - 9.3e-06 26.4 0.0 2.1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFP01322.1 - 9.7e-06 25.5 0.1 3.5e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFP01322.1 - 1.9e-05 24.7 0.1 7.4e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFP01322.1 - 6.4e-05 23.2 0.1 9.6e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 KFP01322.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP01322.1 - 0.00012 21.3 0.1 0.00019 20.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFP01322.1 - 0.00034 20.5 0.0 0.00063 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFP01322.1 - 0.001 18.1 0.0 0.0028 16.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 KFP01322.1 - 0.0013 18.2 0.1 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KFP01322.1 - 0.0023 17.4 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KAP_NTPase PF07693.9 KFP01322.1 - 0.0025 16.8 0.1 0.0041 16.1 0.1 1.6 1 1 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 KFP01322.1 - 0.0028 17.3 0.0 0.0056 16.3 0.0 1.5 2 0 0 2 2 1 1 NACHT domain RNA_helicase PF00910.17 KFP01322.1 - 0.0034 17.5 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 KFP01322.1 - 0.0034 17.1 0.2 0.008 15.9 0.1 1.7 1 1 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 KFP01322.1 - 0.0041 16.5 0.1 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KFP01322.1 - 0.0052 16.5 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 NTPase Miro PF08477.8 KFP01322.1 - 0.0065 16.9 0.1 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KFP01322.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFP01322.1 - 0.013 15.6 0.1 0.029 14.5 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KFP01322.1 - 0.014 14.3 0.1 0.43 9.4 0.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 KFP01322.1 - 0.029 13.9 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 KFP01322.1 - 0.04 13.4 0.0 0.09 12.2 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KFP01322.1 - 0.04 13.5 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFP01322.1 - 0.041 14.2 3.3 0.4 10.9 2.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFP01322.1 - 0.041 13.5 0.2 0.21 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFP01322.1 - 0.044 13.5 0.2 0.098 12.4 0.0 1.7 2 0 0 2 2 1 0 Part of AAA domain NB-ARC PF00931.17 KFP01322.1 - 0.062 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.10 KFP01322.1 - 0.064 11.9 0.0 0.088 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Dynamin_N PF00350.18 KFP01322.1 - 0.069 12.9 0.2 0.076 12.8 0.1 1.4 1 1 0 1 1 1 0 Dynamin family Thymidylate_kin PF02223.12 KFP01322.1 - 0.089 12.1 0.3 0.36 10.1 0.0 2.0 1 1 1 2 2 2 0 Thymidylate kinase AAA_21 PF13304.1 KFP01322.1 - 0.092 12.6 0.5 0.18 11.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KFP01322.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Connexin PF00029.14 KFP01323.1 - 1.1e-51 173.4 0.3 2.4e-51 172.2 0.2 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFP01323.1 - 3.2e-31 106.9 9.9 7.9e-31 105.6 6.9 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain GCV_T_C PF08669.6 KFP01324.1 - 7.2e-08 32.3 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.16 KFP01324.1 - 0.028 13.7 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF4582 PF15189.1 KFP01325.1 - 3.7e-62 208.5 0.6 4.4e-62 208.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4582) ALIX_LYPXL_bnd PF13949.1 KFP01325.1 - 0.021 13.7 0.0 0.056 12.3 0.0 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4608 PF15381.1 KFP01326.1 - 2.4e-26 91.6 5.0 2.7e-26 91.4 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4608) Nterm_IS4 PF13006.2 KFP01326.1 - 0.059 13.3 0.1 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Pkinase PF00069.20 KFP01327.1 - 1.2e-29 103.2 0.0 1.4e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01327.1 - 5.2e-17 61.7 0.0 6.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP01327.1 - 7.1e-06 25.1 0.0 9.9e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP01327.1 - 0.0088 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HALZ PF02183.13 KFP01328.1 - 0.0068 16.0 1.0 0.0068 16.0 0.7 7.1 7 2 2 9 9 9 2 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.17 KFP01328.1 - 0.02 14.9 5.1 0.02 14.9 3.5 5.6 3 1 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain LPP PF04728.8 KFP01328.1 - 0.024 14.4 6.2 1.1 9.0 0.1 4.8 5 0 0 5 5 5 0 Lipoprotein leucine-zipper TMF_DNA_bd PF12329.3 KFP01328.1 - 0.034 13.9 0.4 0.034 13.9 0.3 7.6 4 1 1 6 6 6 0 TATA element modulatory factor 1 DNA binding MmoB_DmpM PF02406.12 KFP01328.1 - 0.057 13.4 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 MmoB/DmpM family Bromodomain PF00439.20 KFP01328.1 - 0.14 12.1 2.3 6.1 6.8 0.1 2.8 2 0 0 2 2 2 0 Bromodomain Reo_sigmaC PF04582.7 KFP01328.1 - 1 8.4 9.7 4.2 6.4 0.8 3.6 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Pro_isomerase PF00160.16 KFP01329.1 - 1.1e-44 152.3 0.3 3.5e-44 150.7 0.2 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 KFP01329.1 - 0.00011 21.7 26.5 0.00011 21.7 18.4 9.5 4 3 5 9 9 9 2 Nuclear RNA-splicing-associated protein DUF4543 PF15076.1 KFP01330.1 - 4.6e-45 151.5 2.7 5.2e-45 151.3 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4543) Noggin PF05806.7 KFP01331.1 - 1.4e-103 344.8 0.4 1.6e-103 344.7 0.3 1.0 1 0 0 1 1 1 1 Noggin Lentiviral_Tat PF02998.9 KFP01331.1 - 7.7 6.4 8.2 6 6.7 0.3 2.4 1 1 0 2 2 2 0 Lentiviral Tat protein SulA PF03846.9 KFP01332.1 - 0.061 13.0 1.1 1.5 8.4 0.1 2.9 3 0 0 3 3 3 0 Cell division inhibitor SulA Tmemb_cc2 PF10267.4 KFP01332.1 - 0.44 9.0 6.1 0.22 10.0 0.1 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein fn3 PF00041.16 KFP01333.1 - 4.4e-12 45.9 0.1 9.4e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Ank_4 PF13637.1 KFP01333.1 - 2.9e-07 30.7 0.0 8.5e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFP01333.1 - 5.1e-06 26.7 0.0 2e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP01333.1 - 7e-06 26.1 0.1 0.0021 18.2 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP01333.1 - 0.0026 17.4 0.3 0.041 13.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Fucokinase PF07959.7 KFP01333.1 - 0.003 16.1 0.1 0.0063 15.1 0.0 1.4 1 0 0 1 1 1 1 L-fucokinase START PF01852.14 KFP01334.1 - 2.1e-31 108.8 0.0 2.3e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 KFP01334.1 - 0.00097 18.8 0.2 0.0032 17.0 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) PIRT PF15099.1 KFP01335.1 - 9.9e-62 205.8 0.5 1.1e-61 205.7 0.3 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Claudin_2 PF13903.1 KFP01335.1 - 0.00019 21.1 0.1 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 KFP01335.1 - 0.0012 18.2 0.3 0.0017 17.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) NfeD PF01957.13 KFP01335.1 - 0.0015 18.6 0.4 0.0019 18.3 0.3 1.1 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding Neurensin PF14927.1 KFP01335.1 - 0.002 17.5 2.7 0.12 11.7 0.1 2.1 1 1 1 2 2 2 2 Neurensin IncA PF04156.9 KFP01335.1 - 0.0029 17.2 1.3 0.0036 16.9 0.9 1.1 1 0 0 1 1 1 1 IncA protein UPF0542 PF15086.1 KFP01335.1 - 0.011 15.4 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 TMEM51 PF15345.1 KFP01335.1 - 0.083 12.5 0.2 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3040 PF11239.3 KFP01335.1 - 0.63 10.1 2.6 1.1 9.3 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) HlyIII PF03006.15 KFP01336.1 - 7.6e-44 149.7 22.2 8.7e-44 149.5 15.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related Meckelin PF09773.4 KFP01336.1 - 0.031 12.0 2.9 0.038 11.7 2.0 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) bZIP_2 PF07716.10 KFP01337.1 - 1.9e-17 62.7 12.6 3.5e-17 61.9 8.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFP01337.1 - 0.00022 21.1 10.0 0.00042 20.2 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.6 KFP01337.1 - 0.011 15.3 0.4 0.02 14.5 0.3 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.12 KFP01337.1 - 0.023 14.9 8.0 0.027 14.7 4.9 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.13 KFP01337.1 - 0.057 13.1 0.5 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 KFP01337.1 - 0.061 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PDZ PF00595.19 KFP01338.1 - 7.3e-11 42.1 0.3 3.7e-10 39.8 0.1 2.2 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) WW PF00397.21 KFP01338.1 - 8.6e-11 41.4 0.6 1.6e-10 40.6 0.4 1.5 1 0 0 1 1 1 1 WW domain HALZ PF02183.13 KFP01338.1 - 0.0024 17.5 3.2 0.0024 17.5 2.2 3.7 4 1 0 4 4 4 1 Homeobox associated leucine zipper PDZ_2 PF13180.1 KFP01338.1 - 0.0087 15.9 0.1 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain DUF948 PF06103.6 KFP01338.1 - 5.2 7.0 10.4 3.6 7.5 0.4 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.7 KFP01338.1 - 7.6 6.2 28.4 0.079 12.7 11.8 2.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CtaG_Cox11 PF04442.9 KFP01339.1 - 3.5e-62 208.6 0.4 4.1e-62 208.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 UCR_Fe-S_N PF10399.4 KFP01339.1 - 0.48 9.6 5.4 1.4 8.1 3.8 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal GAT PF03127.9 KFP01340.1 - 5.7e-26 90.4 1.9 1.1e-25 89.5 1.3 1.5 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 KFP01340.1 - 5.3e-19 68.2 0.2 9.8e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 VHS domain CortBP2 PF09727.4 KFP01340.1 - 0.024 14.1 0.2 0.048 13.1 0.1 1.5 1 0 0 1 1 1 0 Cortactin-binding protein-2 PilM_2 PF11104.3 KFP01340.1 - 0.057 12.3 0.1 0.087 11.7 0.1 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; DUF4611 PF15387.1 KFP01340.1 - 0.13 12.4 0.1 0.44 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Carb_anhydrase PF00194.16 KFP01341.1 - 8.3e-62 208.4 0.0 9.5e-62 208.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1647 PF07801.6 KFP01341.1 - 0.11 12.0 0.2 0.33 10.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) WD40 PF00400.27 KFP01342.1 - 1.4e-10 40.5 0.9 0.31 10.9 0.0 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KFP01342.1 - 0.003 17.0 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain MBT PF02820.13 KFP01343.1 - 1.8e-88 290.4 2.3 2.6e-30 104.1 0.1 4.5 4 0 0 4 4 4 4 mbt repeat NDK PF00334.14 KFP01344.1 - 3.3e-57 192.0 0.0 3.7e-57 191.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.14 KFP01345.1 - 1.8e-56 189.6 0.0 2.1e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Jnk-SapK_ap_N PF09744.4 KFP01346.1 - 1.9e-26 92.9 13.6 1.9e-26 92.9 9.4 3.9 5 0 0 5 5 5 1 JNK_SAPK-associated protein-1 Sipho_Gp157 PF05565.6 KFP01346.1 - 0.0041 16.7 4.1 0.0041 16.7 2.9 2.8 2 0 0 2 2 2 1 Siphovirus Gp157 IncA PF04156.9 KFP01346.1 - 0.083 12.4 35.0 0.054 13.0 5.2 4.2 4 0 0 4 4 4 0 IncA protein Prominin PF05478.6 KFP01346.1 - 1.2 6.5 10.4 0.071 10.6 0.7 2.3 2 0 0 2 2 2 0 Prominin F-protein PF00469.15 KFP01346.1 - 3.1 7.1 11.5 0.042 13.2 2.0 2.3 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef DUF972 PF06156.8 KFP01346.1 - 3.6 7.9 35.4 0.016 15.5 3.2 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF972) BTG PF07742.7 KFP01347.1 - 3.8e-42 142.5 0.0 6.3e-42 141.8 0.0 1.4 1 0 0 1 1 1 1 BTG family PAM2 PF07145.10 KFP01347.1 - 8e-07 28.1 3.3 0.0025 17.1 0.2 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region Kunitz_BPTI PF00014.18 KFP01348.1 - 1.6e-33 114.6 31.3 1.2e-20 73.4 5.1 3.4 3 0 0 3 3 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain I-set PF07679.11 KFP01348.1 - 3.4e-17 62.0 0.0 6.5e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain NTR PF01759.16 KFP01348.1 - 2.6e-11 43.0 0.0 6.6e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Ig_2 PF13895.1 KFP01348.1 - 4e-10 39.6 0.0 1.3e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP01348.1 - 8.1e-08 32.1 0.0 2.3e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Immunoglobulin V-set domain WAP PF00095.16 KFP01348.1 - 5.1e-07 29.5 11.2 5.1e-07 29.5 7.7 4.4 4 1 0 4 4 4 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Ig_3 PF13927.1 KFP01348.1 - 1.1e-06 28.9 0.1 3e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Immunoglobulin domain Kazal_2 PF07648.10 KFP01348.1 - 4.1e-06 26.6 2.9 4.1e-06 26.6 2.0 2.8 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain ig PF00047.20 KFP01348.1 - 6.4e-05 22.9 0.2 0.00032 20.7 0.1 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Porphobil_deam PF01379.15 KFP01348.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain LUC7 PF03194.10 KFP01350.1 - 2.2e-68 230.5 31.1 2.2e-68 230.5 21.5 3.6 1 1 2 3 3 3 1 LUC7 N_terminus MIP-T3 PF10243.4 KFP01350.1 - 0.45 8.9 81.1 0.85 8.0 56.2 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FlbD PF06289.6 KFP01351.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein (FlbD) Ion_trans PF00520.26 KFP01352.1 - 1e-201 664.7 79.8 7.6e-63 211.3 10.3 4.3 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 KFP01352.1 - 1.4e-12 46.7 75.5 8.5e-09 34.3 1.6 9.2 6 3 3 9 9 9 5 Polycystin cation channel EphA2_TM PF14575.1 KFP01352.1 - 0.003 17.9 0.9 45 4.5 0.0 4.7 3 0 0 3 3 3 2 Ephrin type-A receptor 2 transmembrane domain Thioredox_DsbH PF03190.10 KFP01353.1 - 2e-76 255.2 0.0 3.6e-76 254.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KFP01353.1 - 1.7e-11 43.9 0.0 3.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFP01353.1 - 0.00057 20.0 0.1 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain C5-epim_C PF06662.8 KFP01353.1 - 0.051 12.8 0.3 0.28 10.4 0.0 2.2 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus ENTH PF01417.15 KFP01354.1 - 5.1e-52 174.9 0.0 8.1e-52 174.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KFP01354.1 - 1.1e-05 24.3 0.0 1.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 KFP01354.1 - 1.4e-05 24.2 12.4 0.00031 20.0 2.9 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif VHS PF00790.14 KFP01354.1 - 0.00033 20.2 0.2 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 VHS domain MYCBPAP PF14646.1 KFP01355.1 - 1.7e-96 323.5 0.0 3.3e-96 322.6 0.0 1.4 1 0 0 1 1 1 1 MYCBP-associated protein family HemN_C PF06969.11 KFP01356.1 - 6.3e-12 45.3 0.2 1.6e-11 44.0 0.2 1.8 1 0 0 1 1 1 1 HemN C-terminal domain Radical_SAM PF04055.16 KFP01356.1 - 1.9e-08 34.6 0.0 8.7e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily AMP-binding PF00501.23 KFP01357.1 - 1.4e-96 323.4 0.0 1.7e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFP01357.1 - 3.3e-15 56.7 0.0 1.1e-14 55.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 KFP01357.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain LRR_8 PF13855.1 KFP01358.1 - 1.6e-43 146.2 15.3 2.2e-12 46.5 0.2 5.7 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFP01358.1 - 1.1e-23 82.3 26.8 3.4e-06 26.5 0.0 6.8 2 1 9 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP01358.1 - 1.8e-22 75.9 15.9 0.059 13.4 0.0 11.6 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_5 PF13306.1 KFP01358.1 - 4.3e-17 62.0 0.0 3.6e-06 26.7 0.0 2.7 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRRNT PF01462.13 KFP01358.1 - 8.2e-08 31.5 4.9 8.2e-08 31.5 3.4 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFP01358.1 - 8.3e-08 31.5 16.0 10 6.5 0.1 9.7 11 0 0 11 11 11 2 Leucine Rich repeat LRR_7 PF13504.1 KFP01358.1 - 4e-07 29.1 20.7 35 5.2 0.0 10.2 10 0 0 10 10 10 0 Leucine rich repeat LRR_9 PF14580.1 KFP01358.1 - 0.00021 20.9 2.0 0.031 13.8 0.0 3.2 1 1 2 3 3 3 1 Leucine-rich repeat LRR_8 PF13855.1 KFP01359.1 - 1.8e-11 43.5 6.3 2.2e-07 30.5 2.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KFP01359.1 - 4.5e-10 38.1 10.3 0.0057 16.5 0.2 5.6 5 1 0 5 5 4 2 Leucine Rich Repeat LRR_4 PF12799.2 KFP01359.1 - 8.9e-09 34.7 10.3 0.00014 21.4 2.1 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFP01359.1 - 0.00018 21.1 16.8 0.55 10.6 0.1 5.5 5 0 0 5 5 5 2 Leucine rich repeat DUF572 PF04502.8 KFP01359.1 - 0.0059 15.8 18.4 0.0082 15.4 12.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) LRR_6 PF13516.1 KFP01359.1 - 0.016 15.2 10.0 2.6 8.3 0.0 4.9 4 1 1 5 5 5 0 Leucine Rich repeat LMBR1 PF04791.11 KFP01359.1 - 0.048 12.2 1.6 0.058 11.9 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein VIT1 PF01988.14 KFP01359.1 - 0.052 13.0 0.4 0.075 12.5 0.3 1.2 1 0 0 1 1 1 0 VIT family DUF4544 PF15077.1 KFP01359.1 - 0.066 12.7 4.7 0.1 12.1 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) SAPS PF04499.10 KFP01359.1 - 0.1 11.2 4.8 0.13 10.8 3.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2413 PF10310.4 KFP01359.1 - 0.14 10.9 12.7 0.18 10.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ycf1 PF05758.7 KFP01359.1 - 0.16 9.6 8.0 0.18 9.4 5.6 1.1 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 KFP01359.1 - 0.6 9.8 6.5 0.84 9.3 4.5 1.3 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.6 KFP01359.1 - 1.1 7.4 19.3 1.3 7.1 13.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MIP-T3 PF10243.4 KFP01359.1 - 2.1 6.7 29.7 2.8 6.3 20.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 KFP01359.1 - 7.6 5.9 16.2 13 5.1 11.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ERCC4 PF02732.10 KFP01360.1 - 1.3e-06 28.2 1.5 1.8e-06 27.8 0.0 1.9 3 0 0 3 3 3 1 ERCC4 domain Catalase-rel PF06628.7 KFP01360.1 - 0.043 13.6 0.0 0.7 9.8 0.0 2.5 2 0 0 2 2 2 0 Catalase-related immune-responsive BRF1 PF07741.8 KFP01360.1 - 0.08 13.1 7.5 0.75 10.0 0.1 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ribosomal_L27 PF01016.14 KFP01361.1 - 3.9e-29 100.2 0.1 4.9e-29 99.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein DUF347 PF03988.7 KFP01362.1 - 0.11 12.3 0.4 0.13 12.1 0.3 1.1 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF3687 PF12459.3 KFP01362.1 - 0.13 11.4 0.3 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Xylo_C PF12529.3 KFP01363.1 - 1.9e-70 235.8 0.0 3e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.16 KFP01363.1 - 5.7e-54 182.8 2.2 8e-54 182.3 1.5 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Ras PF00071.17 KFP01364.1 - 2.5e-59 199.3 0.1 2.8e-59 199.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01364.1 - 1.8e-18 67.1 0.0 2.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP01364.1 - 3.6e-14 52.3 0.1 4.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP01364.1 - 3.3e-07 29.6 0.0 4.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP01364.1 - 0.00063 19.2 0.1 0.00098 18.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP01364.1 - 0.006 16.5 0.0 0.0097 15.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 KFP01364.1 - 0.036 13.0 0.1 0.091 11.7 0.0 1.7 1 1 0 1 1 1 0 Septin AAA_24 PF13479.1 KFP01364.1 - 0.047 13.2 0.0 0.14 11.7 0.0 1.9 2 1 1 3 3 3 0 AAA domain FeoB_N PF02421.13 KFP01364.1 - 0.079 12.2 0.0 0.64 9.2 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1792 PF08759.6 KFP01364.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1792) AAA_22 PF13401.1 KFP01364.1 - 0.1 12.7 0.0 0.89 9.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain EBP50_C-term PF09007.6 KFP01365.1 - 1.1e-21 76.4 0.7 1.7e-21 75.7 0.5 1.4 1 0 0 1 1 1 1 EBP50, C-terminal PDZ PF00595.19 KFP01365.1 - 2e-14 53.4 0.0 3.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP01365.1 - 3.9e-05 23.4 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFP01365.1 - 0.0077 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF99 PF01949.11 KFP01365.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 Aa_trans PF01490.13 KFP01366.1 - 9.8e-19 67.1 32.1 1.3e-10 40.3 14.4 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFP01366.1 - 5.4e-07 28.7 20.2 0.00042 19.2 0.8 2.6 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Pyr_redox_3 PF13738.1 KFP01367.1 - 0.048 13.7 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FA_desaturase PF00487.19 KFP01368.1 - 5.8e-27 94.7 14.6 7.5e-27 94.3 10.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase TauE PF01925.14 KFP01368.1 - 0.29 10.5 9.0 2.1 7.7 1.0 2.1 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Ank_2 PF12796.2 KFP01369.1 - 1.2e-23 83.2 0.1 8.7e-19 67.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP01369.1 - 2.9e-23 81.8 2.0 1.6e-12 47.6 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFP01369.1 - 5.9e-22 76.3 2.8 8.4e-10 37.9 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFP01369.1 - 3.9e-16 57.5 1.6 1.2e-05 25.0 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFP01369.1 - 7.1e-16 57.8 2.4 1.5e-08 34.6 0.3 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.25 KFP01369.1 - 1.4e-10 41.1 0.1 6e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP01369.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Paramyxo_C PF01692.13 KFP01369.1 - 0.11 12.0 5.9 0.23 11.0 4.1 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Otopetrin PF03189.8 KFP01370.1 - 3.8e-40 138.2 29.8 1.5e-19 70.3 3.1 4.1 3 1 1 4 4 4 3 Otopetrin Adipogenin PF15202.1 KFP01370.1 - 0.076 12.8 1.2 0.4 10.5 0.1 2.8 2 0 0 2 2 2 0 Adipogenin Otopetrin PF03189.8 KFP01371.1 - 1.7e-36 126.2 22.1 1.8e-18 66.7 3.7 3.7 2 1 0 3 3 3 3 Otopetrin Hid1 PF12722.2 KFP01372.1 - 5.9e-248 825.0 0.0 7.5e-247 821.4 0.0 1.9 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KFP01372.1 - 1.3e-228 760.5 0.0 1.5e-228 760.3 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF1664 PF07889.7 KFP01373.1 - 0.99 9.2 25.4 6.1 6.6 0.5 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 KFP01373.1 - 1.5 9.0 33.3 0.022 14.8 8.3 4.8 4 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KFP01373.1 - 1.6 7.8 6.6 2.3 7.3 1.5 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KFP01373.1 - 1.7 8.2 58.8 0.32 10.5 9.5 4.0 3 1 1 4 4 4 0 IncA protein DUF3540 PF12059.3 KFP01373.1 - 2.1 7.9 11.1 7.6 6.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) DUF2573 PF10835.3 KFP01373.1 - 2.8 8.0 10.6 5.1 7.2 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2573) TraB PF01963.12 KFP01373.1 - 4.1 6.7 9.7 0.38 10.1 3.1 2.0 2 1 0 2 2 2 0 TraB family FliD_C PF07195.7 KFP01373.1 - 5 6.3 18.3 1.4 8.1 3.8 3.7 3 1 0 4 4 4 0 Flagellar hook-associated protein 2 C-terminus CCDC155 PF14662.1 KFP01373.1 - 5.6 6.5 55.0 0.33 10.5 9.7 3.3 3 2 0 3 3 3 0 Coiled-coil region of CCDC155 RF-1 PF00472.15 KFP01374.1 - 3.1e-17 62.4 2.7 4.3e-17 61.9 1.9 1.2 1 0 0 1 1 1 1 RF-1 domain DUF2603 PF10788.4 KFP01374.1 - 0.065 12.9 0.6 0.085 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) ATP-cone PF03477.11 KFP01374.1 - 0.073 13.5 1.3 0.18 12.2 0.9 1.6 1 1 0 1 1 1 0 ATP cone domain PET PF06297.9 KFP01374.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 PET Domain Neur_chan_LBD PF02931.18 KFP01375.1 - 3.5e-23 81.9 0.5 4.1e-23 81.6 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Mt_ATP-synt_D PF05873.7 KFP01376.1 - 2.6e-42 144.1 6.9 2.8e-42 144.0 4.8 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) IncA PF04156.9 KFP01376.1 - 0.062 12.9 0.4 0.075 12.6 0.3 1.2 1 0 0 1 1 1 0 IncA protein BTB_2 PF02214.17 KFP01377.1 - 2e-11 43.9 0.0 3.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFP01377.1 - 0.0054 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PadR PF03551.9 KFP01377.1 - 0.11 12.2 0.2 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Arm PF00514.18 KFP01378.1 - 2.3e-11 43.0 0.0 1.6e-05 24.5 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP01378.1 - 0.00011 22.3 0.0 0.002 18.3 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats Arm_2 PF04826.8 KFP01378.1 - 0.0026 16.9 0.3 0.58 9.2 0.0 2.0 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.15 KFP01378.1 - 0.0068 14.7 1.7 0.02 13.2 1.2 1.8 1 1 0 1 1 1 1 Adaptin N terminal region WAPL PF07814.8 KFP01378.1 - 0.007 15.1 0.5 0.0095 14.7 0.3 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin KAP PF05804.7 KFP01378.1 - 0.013 13.4 0.1 0.016 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) HEAT PF02985.17 KFP01378.1 - 0.015 15.3 0.2 5.2 7.4 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat RICTOR_N PF14664.1 KFP01378.1 - 0.015 13.8 0.6 0.025 13.1 0.3 1.5 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term GRIP PF01465.15 KFP01378.1 - 0.02 14.3 0.7 0.2 11.1 0.0 2.6 2 0 0 2 2 2 0 GRIP domain V-ATPase_H_N PF03224.9 KFP01378.1 - 0.03 13.4 0.3 0.037 13.1 0.2 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Cnd3 PF12719.2 KFP01378.1 - 0.033 13.1 0.3 0.039 12.9 0.2 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain ParcG PF10274.4 KFP01378.1 - 0.038 13.9 0.1 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein NT5C PF06941.7 KFP01379.1 - 2.1e-55 187.2 0.1 2.3e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Rad60-SLD PF11976.3 KFP01381.1 - 1e-26 92.3 0.1 1.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFP01381.1 - 1.2e-12 47.0 0.1 1.5e-12 46.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin family Ribosomal_S7 PF00177.16 KFP01382.1 - 1.8e-43 147.6 0.4 2.3e-43 147.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF2722 PF10846.3 KFP01382.1 - 0.072 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Mito_carr PF00153.22 KFP01383.1 - 1.3e-69 229.9 2.8 3.4e-24 84.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3_1 PF00018.23 KFP01384.1 - 7.8e-36 121.2 0.4 1.2e-16 59.7 0.0 2.5 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 KFP01384.1 - 4.5e-34 115.7 0.4 9.2e-16 57.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KFP01384.1 - 1.9e-28 97.7 0.0 6.4e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.19 KFP01384.1 - 1e-24 86.0 0.0 1.7e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.6 KFP01384.1 - 0.0026 17.8 0.1 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.8 KFP01384.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain tRNA_int_end_N2 PF12928.2 KFP01385.1 - 6.6e-19 67.1 0.1 6.6e-19 67.1 0.1 1.9 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KFP01385.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain MyTH4 PF00784.12 KFP01386.1 - 3.5e-29 101.0 0.7 1.2e-28 99.3 0.1 2.2 2 0 0 2 2 2 1 MyTH4 domain FERM_M PF00373.13 KFP01386.1 - 4.8e-09 36.4 0.8 4.8e-09 36.4 0.5 2.2 2 1 0 2 2 2 1 FERM central domain RecQ5 PF06959.6 KFP01387.1 - 1.2e-21 77.2 13.0 3.6e-21 75.7 9.0 1.8 1 0 0 1 1 1 1 RecQ helicase protein-like 5 (RecQ5) DEAD PF00270.24 KFP01387.1 - 8.1e-21 74.2 0.1 2.1e-20 72.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP01387.1 - 2.4e-17 62.5 0.0 2.9e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFP01387.1 - 0.00031 20.6 0.0 0.004 17.0 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3593 PF12159.3 KFP01388.1 - 0.0016 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) Shisa PF13908.1 KFP01388.1 - 0.0046 17.1 3.1 0.0049 17.0 2.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator GP41 PF00517.12 KFP01388.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Retroviral envelope protein Corona_S2 PF01601.11 KFP01388.1 - 0.13 10.3 7.5 0.14 10.2 5.2 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Herpes_LMP2 PF07415.6 KFP01388.1 - 0.22 10.0 3.1 0.21 10.1 2.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Prominin PF05478.6 KFP01388.1 - 0.87 7.0 7.3 0.81 7.1 5.1 1.0 1 0 0 1 1 1 0 Prominin FAM163 PF15069.1 KFP01388.1 - 5.8 7.4 9.3 8.1 7.0 6.4 1.3 1 0 0 1 1 1 0 FAM163 family HCNGP PF07818.8 KFP01389.1 - 1.8e-37 127.2 1.3 3.3e-37 126.3 0.9 1.4 1 0 0 1 1 1 1 HCNGP-like protein DUF2051 PF09738.4 KFP01389.1 - 0.011 15.0 0.3 0.011 15.0 0.2 1.9 3 0 0 3 3 3 0 Double stranded RNA binding protein (DUF2051) Upf2 PF04050.9 KFP01389.1 - 0.74 9.5 9.7 0.13 11.9 3.6 2.1 2 0 0 2 2 2 0 Up-frameshift suppressor 2 NOA36 PF06524.7 KFP01389.1 - 6.3 5.9 11.6 14 4.8 7.5 1.8 2 0 0 2 2 2 0 NOA36 protein GalKase_gal_bdg PF10509.4 KFP01390.1 - 2.2e-20 71.6 0.0 5.4e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KFP01390.1 - 1.6e-14 53.8 0.0 3.1e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KFP01390.1 - 6.7e-13 48.4 0.3 2e-12 46.9 0.2 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain PID PF00640.18 KFP01391.1 - 0.0018 18.2 0.1 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Histone PF00125.19 KFP01392.1 - 4e-33 113.3 0.2 6.3e-33 112.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFP01392.1 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KFP01392.1 - 0.012 14.8 0.7 0.023 13.9 0.5 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 KFP01392.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-CCCH PF00642.19 KFP01393.1 - 7.1e-05 22.3 1.0 7.1e-05 22.3 0.7 7.0 8 0 0 8 8 8 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KFP01393.1 - 0.00021 20.8 10.7 0.00021 20.8 7.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3450 PF11932.3 KFP01393.1 - 0.0025 17.1 2.4 0.0037 16.5 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Laminin_II PF06009.7 KFP01393.1 - 0.0067 16.1 0.7 0.013 15.2 0.5 1.4 1 0 0 1 1 1 1 Laminin Domain II Fez1 PF06818.10 KFP01393.1 - 0.014 15.3 10.1 0.027 14.5 7.0 1.3 1 0 0 1 1 1 0 Fez1 DUF874 PF05917.6 KFP01393.1 - 0.037 12.8 5.3 0.057 12.2 3.7 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) WEMBL PF05701.6 KFP01393.1 - 0.081 11.3 9.4 0.13 10.7 6.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Mnd1 PF03962.10 KFP01393.1 - 0.16 11.6 11.2 4 7.0 7.7 2.5 2 1 0 2 2 2 0 Mnd1 family DUF2205 PF10224.4 KFP01393.1 - 0.67 9.5 4.0 0.25 10.9 0.6 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) APG6 PF04111.7 KFP01393.1 - 1.5 7.7 10.9 2.4 7.1 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 KFP01393.1 - 2.3 5.4 11.8 3.2 4.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) C2 PF00168.25 KFP01394.1 - 6.7e-39 131.6 0.0 1.4e-19 69.7 0.0 2.7 2 1 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.4 KFP01394.1 - 4.8e-18 65.2 11.9 2.2e-09 37.2 0.2 4.0 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain WWbp PF10349.4 KFP01395.1 - 1.5e-19 71.0 17.8 1.5e-19 71.0 12.3 2.3 1 1 1 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 KFP01395.1 - 2e-14 52.8 0.0 2.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 KFP01395.1 - 0.0065 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 KFP01395.1 - 0.025 14.8 0.1 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain SPRY PF00622.23 KFP01396.1 - 1e-05 25.6 5.5 2.1e-05 24.6 2.5 2.4 2 1 0 2 2 2 1 SPRY domain PRY PF13765.1 KFP01396.1 - 0.00039 19.8 0.0 0.0011 18.4 0.0 1.8 1 0 0 1 1 1 1 SPRY-associated domain zf-B_box PF00643.19 KFP01396.1 - 0.0012 18.6 6.9 0.0012 18.6 4.8 1.8 2 0 0 2 2 2 1 B-box zinc finger DUF848 PF05852.6 KFP01396.1 - 0.055 13.3 8.2 0.021 14.7 3.0 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch PF05377.6 KFP01396.1 - 0.33 10.8 3.0 0.88 9.5 1.6 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KFP01396.1 - 0.8 9.2 5.9 1.3 8.5 4.1 1.3 1 0 0 1 1 1 0 IncA protein zf-C3HC4_4 PF15227.1 KFP01397.1 - 1.3e-11 44.1 3.3 1.5e-11 43.9 2.3 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFP01397.1 - 4.6e-10 39.3 5.0 5.2e-10 39.1 3.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP01397.1 - 1e-09 37.8 4.0 1.2e-09 37.6 2.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP01397.1 - 2.2e-08 33.7 5.0 2.5e-08 33.6 3.5 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KFP01397.1 - 3.2e-07 29.9 3.7 3.8e-07 29.6 2.5 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFP01397.1 - 4.1e-07 29.6 5.0 4.9e-07 29.3 3.4 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP01397.1 - 9.4e-07 28.4 3.1 1e-06 28.3 2.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFP01397.1 - 1.5e-06 27.8 1.3 1.6e-06 27.8 0.9 1.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 KFP01397.1 - 0.00032 20.5 0.0 0.00036 20.4 0.0 1.1 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.1 KFP01397.1 - 0.013 15.0 0.9 0.016 14.7 0.6 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 KFP01397.1 - 0.026 14.0 1.1 0.027 14.0 0.7 1.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KFP01397.1 - 0.18 11.9 6.0 0.68 10.0 4.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 KFP01397.1 - 0.33 10.8 3.3 1.6 8.6 2.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger DUF3133 PF11331.3 KFP01397.1 - 1.4 8.5 5.0 3.7 7.2 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) IBR PF01485.16 KFP01397.1 - 1.6 8.6 7.5 8.3 6.3 5.2 1.9 1 1 0 1 1 1 0 IBR domain zf-B_box PF00643.19 KFP01397.1 - 5.8 6.8 7.3 6.8 6.6 1.4 2.1 2 0 0 2 2 2 0 B-box zinc finger PBP PF01161.15 KFP01398.1 - 6.6e-22 77.9 0.1 1e-21 77.3 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein adh_short PF00106.20 KFP01400.1 - 2.2e-24 86.2 0.0 2.9e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP01400.1 - 6.9e-07 29.1 0.0 1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFP01400.1 - 1.5e-05 24.8 0.0 2.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFP01400.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PepSY_TM_1 PF13172.1 KFP01400.1 - 0.0075 15.9 0.7 0.018 14.7 0.5 1.6 1 0 0 1 1 1 1 PepSY-associated TM helix GSG-1 PF07803.6 KFP01401.1 - 5.1e-43 145.4 0.3 8.5e-43 144.7 0.2 1.4 1 0 0 1 1 1 1 GSG1-like protein Claudin_2 PF13903.1 KFP01401.1 - 2.9e-10 40.0 6.9 4.4e-10 39.5 4.8 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP01401.1 - 1.3e-07 31.4 10.0 2.5e-07 30.5 6.9 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HGMIC_fpl PF10242.4 KFP01401.1 - 0.0017 18.3 7.0 0.0047 16.9 4.8 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein 7tm_2 PF00002.19 KFP01402.1 - 3e-79 265.5 18.8 3.7e-79 265.2 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP01402.1 - 2.3e-14 53.1 3.8 5.3e-14 51.9 2.7 1.7 1 0 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.7 KFP01402.1 - 6.4e-05 22.6 1.7 6.5e-05 22.5 0.2 1.7 2 0 0 2 2 2 1 SUR7/PalI family FCH PF00611.18 KFP01403.1 - 9e-22 77.0 5.2 9e-22 77.0 3.6 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFP01403.1 - 2.9e-12 45.9 0.1 5.4e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KFP01403.1 - 1.2e-11 44.2 4.8 3.4e-11 42.7 3.3 1.9 1 0 0 1 1 1 1 WW domain SH3_1 PF00018.23 KFP01403.1 - 3.5e-10 39.1 0.1 6.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP01403.1 - 3.8e-08 32.7 0.1 7.6e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1664 PF07889.7 KFP01403.1 - 0.0038 17.0 4.2 0.0038 17.0 2.9 2.2 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) DUF2229 PF09989.4 KFP01403.1 - 4 6.8 8.6 0.85 9.0 2.8 2.0 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) TPR_MLP1_2 PF07926.7 KFP01403.1 - 9 6.0 26.3 0.7 9.6 1.7 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 KFP01404.1 - 0 1043.1 276.0 0 1029.2 144.9 2.6 1 1 1 2 2 2 2 Myosin tail Myosin_head PF00063.16 KFP01404.1 - 1.3e-269 896.0 0.8 1.3e-269 896.0 0.6 3.8 3 2 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 KFP01404.1 - 7.4e-14 51.1 4.7 2.4e-13 49.4 3.3 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.22 KFP01404.1 - 0.00068 19.0 0.2 0.0033 16.9 0.0 2.3 2 0 0 2 2 2 1 IQ calmodulin-binding motif Filament PF00038.16 KFP01404.1 - 0.00094 18.7 228.4 0.42 10.0 38.6 8.8 1 1 5 6 6 6 3 Intermediate filament protein Reo_sigmaC PF04582.7 KFP01404.1 - 0.0013 18.0 77.8 0.19 10.8 4.8 9.1 2 2 8 10 10 10 8 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KFP01404.1 - 0.0029 17.7 17.6 0.0029 17.7 12.2 11.6 3 2 10 13 13 13 5 Fibrinogen alpha/beta chain family DUF4537 PF15057.1 KFP01404.1 - 0.0055 16.4 0.8 0.029 14.1 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4537) HALZ PF02183.13 KFP01404.1 - 0.0084 15.8 1.2 0.0084 15.8 0.8 14.0 14 3 3 17 17 17 2 Homeobox associated leucine zipper AAA_19 PF13245.1 KFP01404.1 - 0.27 10.9 0.0 0.88 9.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Myosin_tail_1 PF01576.14 KFP01407.1 - 1.8e-280 932.4 246.0 7e-276 917.3 122.9 3.1 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.16 KFP01407.1 - 5.6e-271 900.5 0.5 5.6e-271 900.5 0.4 3.6 2 1 3 5 5 5 1 Myosin head (motor domain) Myosin_N PF02736.14 KFP01407.1 - 1.5e-14 53.3 1.7 4.2e-14 51.9 1.2 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.7 KFP01407.1 - 5.9e-06 25.6 70.7 0.0046 16.1 2.4 9.1 1 1 9 10 10 10 7 Reovirus sigma C capsid protein AAA_27 PF13514.1 KFP01407.1 - 0.00033 18.5 58.4 0.00033 18.5 40.5 5.2 1 1 4 5 5 5 3 AAA domain WEMBL PF05701.6 KFP01407.1 - 0.00041 18.9 69.7 0.00041 18.9 48.3 4.7 1 1 3 4 4 4 1 Weak chloroplast movement under blue light IQ PF00612.22 KFP01407.1 - 0.003 17.0 0.3 0.025 14.1 0.1 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.1 KFP01407.1 - 0.18 11.9 0.0 0.18 11.9 0.0 5.0 4 1 0 4 4 4 0 AAA domain Filament PF00038.16 KFP01407.1 - 0.83 9.0 207.0 0.0086 15.5 40.8 7.8 1 1 5 6 6 6 0 Intermediate filament protein Myosin_head PF00063.16 KFP01410.1 - 3.7e-265 881.3 1.3 3.7e-265 881.3 0.9 3.5 3 2 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFP01410.1 - 7.3e-236 784.9 230.8 3.7e-215 716.4 100.9 5.1 2 1 1 4 4 4 4 Myosin tail Myosin_N PF02736.14 KFP01410.1 - 7.1e-14 51.1 1.1 2e-13 49.7 0.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.7 KFP01410.1 - 1.9e-06 27.3 66.8 0.0039 16.4 2.9 8.1 1 1 5 8 8 8 6 Reovirus sigma C capsid protein Filament PF00038.16 KFP01410.1 - 2.1e-05 24.1 188.7 0.0054 16.2 40.0 7.1 1 1 5 6 6 6 4 Intermediate filament protein IQ PF00612.22 KFP01410.1 - 0.01 15.4 0.5 0.038 13.6 0.1 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.1 KFP01410.1 - 0.19 11.9 0.0 0.19 11.9 0.0 5.0 4 0 0 4 4 4 0 AAA domain IncA PF04156.9 KFP01410.1 - 7.1 6.1 216.4 0.05 13.2 12.1 10.7 2 1 10 12 12 12 0 IncA protein Myosin_tail_1 PF01576.14 KFP01413.1 - 0 1063.1 272.1 0 1045.8 141.3 3.1 2 1 1 3 3 3 3 Myosin tail Myosin_head PF00063.16 KFP01413.1 - 9.6e-261 866.7 2.1 9.6e-261 866.7 1.5 4.0 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 KFP01413.1 - 2.3e-14 52.7 1.9 6.7e-14 51.2 1.3 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Reo_sigmaC PF04582.7 KFP01413.1 - 0.022 13.9 75.8 0.82 8.7 4.4 9.6 2 2 6 10 10 10 0 Reovirus sigma C capsid protein IQ PF00612.22 KFP01413.1 - 0.022 14.3 0.9 0.07 12.7 0.2 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif Filament PF00038.16 KFP01413.1 - 0.025 14.0 227.3 0.0065 15.9 38.1 7.8 1 1 6 7 7 7 0 Intermediate filament protein AAA_22 PF13401.1 KFP01413.1 - 0.2 11.8 0.0 0.2 11.8 0.0 4.9 3 1 0 3 3 3 0 AAA domain Myosin_tail_1 PF01576.14 KFP01415.1 - 1.1e-275 916.6 261.0 6.3e-274 910.8 140.2 2.7 2 1 0 2 2 2 2 Myosin tail Myosin_head PF00063.16 KFP01415.1 - 2.2e-266 885.3 0.6 2.2e-266 885.3 0.4 3.8 4 1 1 5 5 5 1 Myosin head (motor domain) Myosin_N PF02736.14 KFP01415.1 - 1e-10 41.1 1.7 3.1e-10 39.5 1.2 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 KFP01415.1 - 0.22 11.6 0.0 0.22 11.6 0.0 4.7 4 1 0 4 4 4 0 AAA domain SCO1-SenC PF02630.9 KFP01417.1 - 2e-47 161.0 0.0 2.3e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KFP01417.1 - 2.4e-06 27.2 0.0 4.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KFP01417.1 - 7.1e-05 22.8 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TMEM220 PF15071.1 KFP01418.1 - 7.1e-11 42.4 0.4 7.1e-11 42.4 0.3 1.6 2 0 0 2 2 2 1 Transmembrane family 220, helix RPEL PF02755.10 KFP01419.1 - 9.3e-21 72.5 6.4 4.4e-07 29.0 0.0 3.5 3 0 0 3 3 3 3 RPEL repeat SAP PF02037.22 KFP01419.1 - 7.2e-10 38.1 1.7 1.1e-09 37.5 0.1 2.1 2 0 0 2 2 2 1 SAP domain Lactamase_B_2 PF12706.2 KFP01420.1 - 2.2e-30 105.6 0.1 4.2e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFP01420.1 - 3.8e-07 29.9 0.0 6e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PI3K_1B_p101 PF10486.4 KFP01423.1 - 1.4e-42 145.3 0.1 2e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TnpW PF14202.1 KFP01423.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpW NTR PF01759.16 KFP01424.1 - 8.1e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 UNC-6/NTR/C345C module TIMP PF00965.12 KFP01424.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase zf-C3HC4_4 PF15227.1 KFP01425.1 - 2e-09 37.1 8.0 2.2e-09 37.0 5.6 1.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFP01425.1 - 2.1e-08 33.6 5.7 2.2e-08 33.5 4.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP01425.1 - 3e-08 33.3 6.3 3.1e-08 33.2 4.4 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP01425.1 - 7.6e-08 32.2 7.8 7.9e-08 32.1 5.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFP01425.1 - 3.4e-06 26.6 6.6 4.1e-06 26.3 4.6 1.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFP01425.1 - 3.7e-06 26.4 5.5 4.1e-06 26.3 3.8 1.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP01425.1 - 0.00013 21.6 7.7 0.00016 21.3 5.3 1.1 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFP01425.1 - 0.0098 15.4 2.1 0.01 15.3 1.5 1.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 U-box PF04564.10 KFP01425.1 - 0.084 12.8 0.0 0.089 12.7 0.0 1.0 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.3 KFP01425.1 - 0.12 11.8 2.4 0.15 11.5 1.7 1.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KFP01425.1 - 0.14 11.9 4.7 0.14 11.9 3.3 1.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KFP01425.1 - 0.5 10.5 6.4 3.3 7.8 4.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger IBR PF01485.16 KFP01425.1 - 3 7.8 7.6 21 5.1 5.3 1.9 1 1 0 1 1 1 0 IBR domain zf-RING_4 PF14570.1 KFP01425.1 - 3.8 7.1 7.2 0.59 9.7 0.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Tfb4 PF03850.9 KFP01425.1 - 5.7 6.1 5.9 5.8 6.0 4.1 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 Peptidase_S10 PF00450.17 KFP01427.1 - 1.8e-84 284.3 0.8 2e-84 284.2 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ACP_syn_III_C PF08541.5 KFP01427.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal bZIP_1 PF00170.16 KFP01428.1 - 0.00017 21.5 4.9 0.00017 21.5 3.4 6.1 3 1 4 7 7 7 2 bZIP transcription factor bZIP_2 PF07716.10 KFP01428.1 - 0.0034 17.1 4.4 0.0034 17.1 3.1 5.4 5 1 0 5 5 5 1 Basic region leucine zipper DUF904 PF06005.7 KFP01428.1 - 0.0059 16.8 6.4 0.0059 16.8 4.5 5.8 3 2 2 5 5 5 2 Protein of unknown function (DUF904) HAP1_N PF04849.8 KFP01428.1 - 0.46 9.3 40.6 0.021 13.8 16.6 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Shugoshin_N PF07558.6 KFP01428.1 - 0.53 10.0 16.0 2 8.1 0.7 4.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region MbeD_MobD PF04899.7 KFP01428.1 - 0.71 9.8 11.8 0.76 9.7 1.4 4.3 3 1 2 5 5 5 0 MbeD/MobD like NPV_P10 PF05531.7 KFP01428.1 - 1.7 8.9 15.2 1 9.6 1.5 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 KFP01428.1 - 1.8 8.9 34.3 6.9 7.0 6.4 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Leu_zip PF15294.1 KFP01428.1 - 3 6.8 40.5 6.7 5.7 12.0 3.6 1 1 2 3 3 3 0 Leucine zipper Ax_dynein_light PF10211.4 KFP01428.1 - 3.1 7.5 36.8 5.9 6.6 7.1 3.6 1 1 3 4 4 4 0 Axonemal dynein light chain Tropomyosin_1 PF12718.2 KFP01428.1 - 5.7 6.7 42.5 7.8 6.3 1.6 3.8 2 1 0 2 2 2 0 Tropomyosin like U3_assoc_6 PF08640.6 KFP01429.1 - 2.3e-16 59.2 4.7 2.3e-16 59.2 3.3 2.7 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KFP01429.1 - 0.00017 21.9 2.8 18 6.3 0.2 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.5 KFP01429.1 - 0.00037 19.4 25.0 0.12 11.2 4.6 3.3 2 1 1 3 3 3 3 NRDE-2, necessary for RNA interference VEFS-Box PF09733.4 KFP01430.1 - 4.2e-56 188.5 3.1 8.6e-56 187.5 2.1 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein zf-H2C2_5 PF13909.1 KFP01430.1 - 1.4 9.2 5.1 5.6 7.3 3.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFP01430.1 - 4.4 7.8 6.7 20 5.7 4.6 2.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type AAA PF00004.24 KFP01431.1 - 7.9e-09 35.8 0.3 2.4e-06 27.7 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP01431.1 - 0.00034 20.7 0.7 0.0015 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFP01431.1 - 0.00041 21.1 2.1 0.0017 19.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFP01431.1 - 0.0013 18.7 0.8 0.0062 16.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 KFP01431.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 KFP01431.1 - 0.013 14.5 0.0 0.036 13.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArfGap PF01412.13 KFP01432.1 - 3.7e-26 91.2 0.0 7.4e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 KFP01432.1 - 2.8e-14 53.1 1.2 6.9e-06 26.2 0.1 3.1 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 KFP01432.1 - 1.1e-11 44.9 5.6 9.7e-06 25.8 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFP01432.1 - 3e-08 33.6 4.6 0.0019 18.2 0.1 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 KFP01432.1 - 0.00076 19.4 1.6 0.0022 17.8 0.0 2.4 2 2 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 KFP01432.1 - 0.09 12.9 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Rhomboid PF01694.17 KFP01433.1 - 1e-33 116.3 11.0 1e-33 116.3 7.6 2.2 3 0 0 3 3 3 1 Rhomboid family EF-hand_7 PF13499.1 KFP01433.1 - 8.4e-08 32.2 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFP01433.1 - 7.2e-07 28.7 0.0 8.4e-05 22.1 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP01433.1 - 9.4e-07 27.7 0.0 0.016 14.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP01433.1 - 0.003 17.2 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.1 KFP01433.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Njmu-R1 PF15053.1 KFP01434.1 - 1.2e-194 645.9 6.1 5.8e-194 643.6 4.2 1.8 1 1 0 1 1 1 1 Mjmu-R1-like protein family DUF3449 PF11931.3 KFP01435.1 - 0.23 10.9 3.5 2.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-FCS PF06467.9 KFP01435.1 - 2 8.1 6.0 0.26 10.9 1.1 1.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RNA_pol_Rpb2_2 PF04561.9 KFP01436.1 - 0.0018 17.7 0.6 0.0042 16.5 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 TPR_19 PF14559.1 KFP01436.1 - 0.0035 17.6 0.4 0.0035 17.6 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF356 PF04009.7 KFP01436.1 - 0.11 12.6 0.1 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF356) Pkinase PF00069.20 KFP01437.1 - 8.1e-46 156.2 0.0 1.2e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KFP01437.1 - 6.9e-45 152.0 0.3 1.2e-44 151.2 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KFP01437.1 - 5.3e-26 91.2 0.0 8.4e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KFP01437.1 - 2.2e-07 30.5 0.0 0.015 14.7 0.0 2.6 1 1 0 2 2 2 2 PQQ-like domain APH PF01636.18 KFP01437.1 - 1.3e-05 25.0 0.2 0.11 12.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family PQQ PF01011.16 KFP01437.1 - 3.3e-05 23.1 0.3 0.032 13.7 0.0 3.6 5 0 0 5 5 5 2 PQQ enzyme repeat Kdo PF06293.9 KFP01437.1 - 0.0033 16.5 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFP01437.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ig_2 PF13895.1 KFP01438.1 - 4.4e-42 142.0 2.8 6.2e-08 32.6 0.0 6.2 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFP01438.1 - 8.6e-17 61.3 5.1 0.0032 17.9 0.0 7.0 6 2 0 6 6 6 4 Immunoglobulin domain I-set PF07679.11 KFP01438.1 - 8.7e-13 47.9 11.2 0.18 11.6 0.2 7.7 6 3 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.12 KFP01438.1 - 3e-11 43.2 1.9 0.31 10.9 0.0 7.1 6 1 0 6 6 6 4 Immunoglobulin V-set domain ig PF00047.20 KFP01438.1 - 0.00018 21.5 11.7 18 5.5 0.0 7.5 6 3 0 6 6 6 1 Immunoglobulin domain C2-set PF05790.10 KFP01438.1 - 0.0013 18.6 0.4 13 5.8 0.0 5.0 5 0 0 5 5 5 1 Immunoglobulin C2-set domain ICAM_N PF03921.9 KFP01438.1 - 0.0074 15.7 2.9 0.031 13.7 0.1 3.1 3 0 0 3 3 3 1 Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 PF13895.1 KFP01439.1 - 8.2e-21 73.9 2.2 2.4e-10 40.3 0.1 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP01439.1 - 6.9e-13 48.9 2.8 3.5e-05 24.2 0.0 2.7 1 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP01439.1 - 9.5e-10 38.4 0.5 0.00054 20.0 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 KFP01439.1 - 1e-09 38.0 0.0 0.0004 20.1 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFP01439.1 - 2.6e-07 30.5 6.0 0.017 15.0 0.4 4.0 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP01439.1 - 7.9e-05 22.4 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain HGTP_anticodon PF03129.15 KFP01440.1 - 5.2e-11 42.3 0.0 8.4e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 KFP01440.1 - 0.019 14.5 0.0 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) DEAD PF00270.24 KFP01441.1 - 2.6e-42 144.1 0.0 1.4e-41 141.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase P68HR PF08061.6 KFP01441.1 - 3.5e-27 93.7 18.1 1.4e-14 53.4 2.2 2.6 2 0 0 2 2 2 2 P68HR (NUC004) repeat Helicase_C PF00271.26 KFP01441.1 - 2.4e-22 78.5 0.0 1.4e-21 76.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP01441.1 - 0.00047 20.0 0.0 0.019 14.7 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HECT PF00632.20 KFP01442.1 - 1.7e-101 339.5 0.0 2.4e-101 339.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFP01442.1 - 2.8e-29 100.6 10.9 1.3e-10 40.9 0.2 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KFP01442.1 - 6.5e-15 54.7 0.1 1.2e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 C2 domain Arm PF00514.18 KFP01443.1 - 5.2e-80 260.8 9.1 7.9e-12 44.5 0.0 9.0 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 KFP01443.1 - 1.4e-25 89.2 7.8 2.9e-25 88.2 5.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 KFP01443.1 - 2.5e-16 59.7 0.2 0.00033 20.8 0.0 6.0 1 1 3 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 KFP01443.1 - 7.1e-15 54.9 0.3 0.00015 22.1 0.0 5.3 3 1 3 6 6 6 3 HEAT-like repeat HEAT PF02985.17 KFP01443.1 - 3e-07 29.9 5.1 0.043 13.9 0.0 5.8 8 0 0 8 8 8 2 HEAT repeat V-ATPase_H_C PF11698.3 KFP01443.1 - 0.024 14.5 0.9 15 5.5 0.1 3.4 4 1 0 4 4 4 0 V-ATPase subunit H NTR PF01759.16 KFP01444.1 - 0.055 13.0 0.1 0.23 11.0 0.1 1.9 1 1 0 1 1 1 0 UNC-6/NTR/C345C module Bromodomain PF00439.20 KFP01445.1 - 3.6e-26 90.9 0.1 8.2e-26 89.7 0.1 1.7 1 0 0 1 1 1 1 Bromodomain DDT PF02791.12 KFP01445.1 - 9.4e-22 76.5 0.3 1.9e-21 75.5 0.2 1.6 1 0 0 1 1 1 1 DDT domain PHD PF00628.24 KFP01445.1 - 4e-18 64.8 28.8 1.4e-09 37.4 5.0 3.0 2 0 0 2 2 2 2 PHD-finger WHIM1 PF15612.1 KFP01445.1 - 4.8e-06 26.2 0.0 1.3e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KFP01445.1 - 0.0017 18.2 1.7 0.0031 17.3 0.2 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 C1_1 PF00130.17 KFP01445.1 - 0.57 9.9 14.3 3.1 7.6 0.9 2.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KFP01445.1 - 1.3 8.3 18.1 0.82 9.0 4.2 2.7 2 0 0 2 2 2 0 PHD-finger Utp12 PF04003.7 KFP01446.1 - 0.006 16.4 1.5 0.016 15.0 0.1 2.6 3 0 0 3 3 3 1 Dip2/Utp12 Family NUC205 PF08168.6 KFP01446.1 - 0.012 14.9 0.1 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 NUC205 domain AlgF PF11182.3 KFP01446.1 - 0.12 12.0 0.1 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF IP_trans PF02121.13 KFP01447.1 - 3e-68 229.7 4.7 6.1e-68 228.7 3.2 1.4 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein PCI PF01399.22 KFP01448.1 - 4.2e-23 81.6 0.9 2.2e-22 79.3 0.0 2.5 2 1 0 2 2 2 1 PCI domain DUF4488 PF14869.1 KFP01448.1 - 0.017 14.6 0.0 0.052 13.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Tubulin_C PF03953.12 KFP01448.1 - 0.033 14.2 0.1 0.19 11.7 0.0 2.2 1 1 1 2 2 2 0 Tubulin C-terminal domain AAA_12 PF13087.1 KFP01449.1 - 6.9e-34 116.9 0.0 1.4e-33 115.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFP01449.1 - 2.8e-29 102.3 6.5 3.5e-15 56.2 0.1 3.5 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 KFP01449.1 - 6.6e-09 35.6 0.0 1.1e-07 31.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFP01449.1 - 2e-08 33.8 0.0 7.9e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain zf-CCCH PF00642.19 KFP01449.1 - 7.4e-08 31.9 0.7 1.8e-07 30.6 0.5 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PhoH PF02562.11 KFP01449.1 - 2.1e-05 23.8 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.16 KFP01449.1 - 8.8e-05 21.9 0.0 8.8e-05 21.9 0.0 2.8 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 KFP01449.1 - 0.00013 21.8 0.1 0.00091 19.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PAM2 PF07145.10 KFP01449.1 - 0.00025 20.3 0.0 0.0011 18.2 0.0 2.3 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_14 PF13173.1 KFP01449.1 - 0.0022 17.8 0.1 0.56 10.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain UvrD_C PF13361.1 KFP01449.1 - 0.0061 16.0 0.8 0.16 11.4 0.0 2.8 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 KFP01449.1 - 0.021 14.9 0.2 0.18 11.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFP01449.1 - 0.032 14.2 0.2 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Helicase_RecD PF05127.9 KFP01449.1 - 0.039 13.5 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 0 Helicase AAA_5 PF07728.9 KFP01449.1 - 0.15 11.8 0.2 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KFP01449.1 - 0.16 11.3 0.0 0.48 9.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Claudin_2 PF13903.1 KFP01450.1 - 3.6e-28 98.4 2.3 4.9e-28 97.9 1.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP01450.1 - 1.7e-14 53.8 7.6 3.7e-08 33.2 2.6 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF805 PF05656.9 KFP01450.1 - 0.00047 19.9 0.7 0.00047 19.9 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF805) Clc-like PF07062.7 KFP01450.1 - 0.015 14.5 3.2 0.036 13.3 2.2 1.7 1 1 0 1 1 1 0 Clc-like DUF1049 PF06305.6 KFP01450.1 - 0.022 14.2 6.5 0.17 11.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF2206 PF09971.4 KFP01450.1 - 0.11 11.3 1.7 0.11 11.3 0.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2206) Claudin_3 PF06653.6 KFP01450.1 - 0.29 10.8 7.3 1.9 8.2 2.5 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF981 PF06168.6 KFP01450.1 - 0.39 10.4 4.1 0.24 11.1 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF981) DUF983 PF06170.7 KFP01450.1 - 1.8 8.7 4.5 3.1 7.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF983) zf-LITAF-like PF10601.4 KFP01450.1 - 4.4 7.2 6.4 3.7 7.4 0.0 2.7 3 0 0 3 3 2 0 LITAF-like zinc ribbon domain DUF2721 PF11026.3 KFP01450.1 - 8.1 6.0 9.7 0.9 9.1 0.5 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF2721) PMP22_Claudin PF00822.15 KFP01451.1 - 1.2e-24 86.7 0.0 2.2e-24 85.9 0.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP01451.1 - 1.7e-11 44.0 0.0 2.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.1 KFP01451.1 - 0.0011 17.5 0.2 0.0016 17.0 0.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2269 PF10027.4 KFP01451.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) TMEM173 PF15009.1 KFP01451.1 - 0.027 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 DUF4225 PF13988.1 KFP01451.1 - 0.037 13.4 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DuoxA PF10204.4 KFP01451.1 - 0.088 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor Yae1_N PF09811.4 KFP01452.1 - 2.2e-12 46.2 32.7 4.9 6.7 22.7 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal PMP22_Claudin PF00822.15 KFP01453.1 - 1.7e-21 76.6 3.9 3.7e-21 75.4 2.7 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP01453.1 - 2.9e-19 69.4 3.1 3.8e-19 69.0 2.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 KFP01453.1 - 0.00013 21.3 2.5 0.00024 20.4 1.6 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF716 PF04819.7 KFP01453.1 - 0.044 13.2 0.5 0.083 12.3 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF716) Claudin_3 PF06653.6 KFP01453.1 - 0.57 9.8 10.9 6 6.5 7.6 1.9 1 1 0 1 1 1 0 Tight junction protein, Claudin-like SUR7 PF06687.7 KFP01453.1 - 0.68 9.4 12.8 3 7.3 8.0 2.3 1 1 1 2 2 2 0 SUR7/PalI family DUF2627 PF11118.3 KFP01453.1 - 0.94 9.6 6.6 11 6.2 4.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) MFS_1 PF07690.11 KFP01453.1 - 2.3 6.8 14.7 21 3.6 10.6 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily C2 PF00168.25 KFP01454.1 - 1.3e-27 95.4 0.2 2.4e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 KFP01454.1 - 1.8e-20 73.1 0.0 3.5e-12 46.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain C1_1 PF00130.17 KFP01454.1 - 4.2e-17 61.5 16.2 1e-15 57.1 3.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.12 KFP01454.1 - 5.9e-09 35.3 0.0 3.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KFP01454.1 - 6.8e-08 32.9 0.4 1.7e-07 31.6 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain RVT_1 PF00078.22 KFP01454.1 - 0.005 16.2 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) C1_3 PF07649.7 KFP01454.1 - 0.092 12.7 17.3 0.03 14.3 3.9 2.8 2 0 0 2 2 2 0 C1-like domain Sushi PF00084.15 KFP01455.1 - 6e-42 141.8 26.5 2.1e-12 47.1 0.7 5.1 5 0 0 5 5 5 4 Sushi domain (SCR repeat) Sushi_2 PF09014.5 KFP01455.1 - 5.6e-26 90.1 3.2 7.7e-25 86.4 1.3 3.1 3 0 0 3 3 3 1 Beta-2-glycoprotein-1 fifth domain HRM PF02793.17 KFP01455.1 - 0.018 15.0 12.6 9.8 6.2 0.1 4.5 4 0 0 4 4 4 0 Hormone receptor domain Meleagrin PF08189.6 KFP01455.1 - 1.9 8.0 15.7 0.46 10.0 0.8 4.1 5 0 0 5 5 5 0 Meleagrin/Cygnin family cEGF PF12662.2 KFP01455.1 - 4.1 7.1 7.8 6.4 6.5 0.3 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like DUF148 PF02520.12 KFP01456.1 - 0.011 15.5 10.4 0.011 15.5 7.2 8.7 1 1 7 8 8 8 0 Domain of unknown function DUF148 Tup_N PF08581.5 KFP01456.1 - 0.019 15.1 11.1 0.019 15.1 7.7 10.7 2 2 7 11 11 11 0 Tup N-terminal RGS PF00615.14 KFP01457.1 - 1.2e-31 109.2 0.0 2.2e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain G-gamma PF00631.17 KFP01457.1 - 7.9e-11 41.5 0.0 2.1e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 GGL domain DEP PF00610.16 KFP01457.1 - 6.5e-08 32.2 0.1 3.9e-07 29.7 0.0 2.4 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-alpha PF00503.15 KFP01458.1 - 1.5e-117 392.5 2.7 1.7e-117 392.4 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP01458.1 - 2.3e-17 62.8 2.2 4.2e-13 48.9 0.1 3.4 3 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP01458.1 - 0.00019 20.6 3.2 0.003 16.7 0.3 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP01458.1 - 0.0048 16.3 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 KFP01458.1 - 0.025 15.0 0.0 0.31 11.5 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KFP01458.1 - 0.026 14.4 0.0 8.6 6.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ras PF00071.17 KFP01458.1 - 0.046 13.1 0.4 5.2 6.4 0.0 2.7 2 1 0 2 2 2 0 Ras family AAA_29 PF13555.1 KFP01458.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.11 KFP01459.1 - 2.1e-38 131.9 19.5 2.2e-36 125.3 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFP01459.1 - 1.4e-06 26.9 35.3 9.8e-06 24.2 8.0 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 KFP01459.1 - 0.00013 20.7 31.7 0.00048 18.8 7.8 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 KFP01459.1 - 0.95 9.2 12.1 0.69 9.7 0.8 3.7 3 1 0 3 3 3 0 MFS_1 like family Sulfatase PF00884.18 KFP01460.1 - 3.4e-67 226.8 0.0 4.9e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFP01460.1 - 4.4e-20 72.3 0.0 8.8e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFP01460.1 - 2.6e-05 23.6 0.0 0.00029 20.2 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase WD40 PF00400.27 KFP01461.1 - 0.00024 20.8 0.3 0.1 12.5 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat BCAS3 PF12490.3 KFP01461.1 - 0.022 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 DUF1193 PF06702.7 KFP01462.1 - 3.5e-71 239.1 0.2 1.5e-45 155.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1193) FAM198 PF15051.1 KFP01462.1 - 0.00097 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 FAM198 protein ABC_tran PF00005.22 KFP01463.1 - 4e-60 202.0 0.2 2.4e-31 108.8 0.2 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFP01463.1 - 2.1e-32 112.5 43.4 4.3e-24 85.2 15.7 2.6 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFP01463.1 - 3e-23 83.2 1.5 6.1e-08 32.9 0.0 4.8 3 1 1 4 4 4 4 AAA domain DUF258 PF03193.11 KFP01463.1 - 3.9e-10 39.1 1.4 0.00016 20.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFP01463.1 - 2.9e-06 26.7 3.3 0.01 15.3 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFP01463.1 - 4.4e-05 22.7 0.2 0.42 9.5 0.2 3.4 3 1 1 4 4 4 2 AAA ATPase domain SMC_N PF02463.14 KFP01463.1 - 5.3e-05 22.5 2.5 0.035 13.3 0.1 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFP01463.1 - 0.00045 20.2 0.4 0.013 15.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KFP01463.1 - 0.00091 19.1 0.2 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFP01463.1 - 0.0018 18.4 0.2 0.94 9.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFP01463.1 - 0.0026 17.1 1.0 0.25 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFP01463.1 - 0.0068 15.8 0.8 3.6 6.9 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain MMR_HSR1 PF01926.18 KFP01463.1 - 0.0077 16.1 0.2 2.1 8.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 KFP01463.1 - 0.013 15.8 11.3 0.033 14.5 0.1 3.1 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.1 KFP01463.1 - 0.018 14.6 0.1 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFP01463.1 - 0.019 14.8 0.0 3 7.8 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KFP01463.1 - 0.032 15.0 0.2 1.9 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KFP01463.1 - 0.047 13.3 2.9 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KFP01463.1 - 0.053 14.0 0.0 3.5 8.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Rad17 PF03215.10 KFP01463.1 - 0.065 11.9 1.6 1.5 7.3 0.2 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA PF00004.24 KFP01463.1 - 0.11 12.7 0.4 38 4.4 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFP01463.1 - 0.28 11.1 0.2 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFP01463.1 - 0.45 10.3 3.4 2.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain Dynamin_N PF00350.18 KFP01463.1 - 0.6 9.9 4.6 0.75 9.5 0.0 2.8 3 0 0 3 3 2 0 Dynamin family AAA_18 PF13238.1 KFP01463.1 - 0.81 9.9 4.3 5 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 KFP01463.1 - 1.1 8.7 4.5 1.4 8.2 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 KFP01463.1 - 2.4 7.7 3.4 9.4 5.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFP01464.1 - 1.3e-07 31.9 0.0 2.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFP01464.1 - 1e-06 28.9 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KFP01466.1 - 1.4e-05 24.3 10.2 1.7e-05 24.0 7.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 KFP01466.1 - 6e-05 23.3 0.2 8.5e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 ABC transporter OpgC_C PF10129.4 KFP01466.1 - 0.0041 15.8 0.7 0.0049 15.5 0.5 1.2 1 0 0 1 1 1 1 OpgC protein AAA_29 PF13555.1 KFP01466.1 - 0.016 14.7 0.3 0.028 13.9 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KFP01466.1 - 0.065 12.4 0.1 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KFP01467.1 - 8e-08 31.6 0.3 8e-08 31.6 0.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3112 PF11309.3 KFP01467.1 - 0.049 13.4 1.3 0.1 12.4 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) ABC_tran PF00005.22 KFP01468.1 - 7.7e-59 197.8 0.0 6.3e-28 97.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFP01468.1 - 3.2e-34 118.5 62.1 2e-26 92.8 15.5 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFP01468.1 - 1.2e-17 64.7 0.0 5.7e-07 29.7 0.0 4.8 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFP01468.1 - 3.3e-10 39.4 0.1 0.00041 19.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFP01468.1 - 3.4e-07 29.7 0.5 0.034 13.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFP01468.1 - 2.6e-06 26.7 0.1 0.7 8.8 0.0 4.5 5 0 0 5 5 5 2 AAA ATPase domain AAA_23 PF13476.1 KFP01468.1 - 3.7e-05 24.1 6.1 0.029 14.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KFP01468.1 - 5.9e-05 23.1 0.2 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 KFP01468.1 - 0.00011 22.1 0.1 0.095 12.6 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 KFP01468.1 - 0.00036 19.9 0.1 0.21 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFP01468.1 - 0.00049 19.6 0.4 0.2 11.0 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain Dynamin_N PF00350.18 KFP01468.1 - 0.00061 19.6 0.0 0.027 14.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 KFP01468.1 - 0.001 19.1 1.2 1.1 9.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFP01468.1 - 0.0015 19.3 0.0 0.98 10.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFP01468.1 - 0.0017 17.6 0.2 2.9 7.0 0.0 3.8 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 KFP01468.1 - 0.0017 17.7 0.1 1.6 8.1 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.1 KFP01468.1 - 0.0022 17.8 0.2 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFP01468.1 - 0.0026 17.4 0.5 0.64 9.7 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KFP01468.1 - 0.0043 15.9 3.4 6.6 5.4 0.3 3.3 3 0 0 3 3 3 0 NB-ARC domain AAA PF00004.24 KFP01468.1 - 0.0047 17.1 0.0 2.9 8.0 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KFP01468.1 - 0.005 16.5 0.3 3.2 7.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFP01468.1 - 0.0065 16.6 0.1 3.9 7.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 KFP01468.1 - 0.0074 15.7 1.3 0.64 9.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KFP01468.1 - 0.0092 15.5 0.1 3.7 7.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KFP01468.1 - 0.012 15.5 0.0 4.3 7.3 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KFP01468.1 - 0.014 15.0 0.6 9.7 5.8 0.1 3.3 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.1 KFP01468.1 - 0.017 14.8 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 KFP01468.1 - 0.028 14.0 1.5 2.8 7.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 KFP01468.1 - 0.038 12.9 0.1 2.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 KFP01468.1 - 0.046 13.2 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.16 KFP01468.1 - 0.09 11.9 0.0 13 4.8 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KFP01468.1 - 0.13 12.2 0.2 17 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KFP01468.1 - 0.16 10.9 2.1 8.4 5.3 0.0 3.1 3 0 0 3 3 3 0 Septin ArgK PF03308.11 KFP01468.1 - 0.21 10.3 0.8 0.49 9.1 0.1 1.8 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 KFP01468.1 - 0.39 11.2 4.4 7.3 7.1 0.0 3.2 4 0 0 4 4 2 0 Miro-like protein Pkinase PF00069.20 KFP01469.1 - 1.9e-46 158.3 0.0 2.2e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01469.1 - 1.4e-32 112.7 0.0 1.7e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP01469.1 - 1.9e-05 23.8 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFP01469.1 - 0.0026 16.6 0.2 0.0038 16.0 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KFP01469.1 - 0.0076 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP01469.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase IRK PF01007.15 KFP01472.1 - 2.1e-140 467.3 2.0 2.5e-140 467.0 1.4 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP01472.1 - 0.0015 18.1 4.4 0.0038 16.9 3.0 1.8 1 1 0 1 1 1 1 Ion channel IRK PF01007.15 KFP01473.1 - 1e-171 570.2 2.4 1.3e-171 569.9 1.7 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.5 KFP01473.1 - 1.5e-29 101.6 1.2 3e-29 100.6 0.8 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.11 KFP01473.1 - 0.0025 17.4 8.2 0.006 16.2 5.7 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KFP01473.1 - 0.32 10.2 7.3 0.49 9.6 5.1 1.2 1 0 0 1 1 1 0 Ion transport protein Sox_N PF12444.3 KFP01474.1 - 2.2e-27 95.9 0.4 2.2e-27 95.9 0.3 3.1 3 1 0 3 3 3 1 Sox developmental protein N terminal HMG_box PF00505.14 KFP01474.1 - 3.5e-25 88.0 1.3 7.4e-25 87.0 0.9 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP01474.1 - 8.6e-11 42.0 1.0 1.6e-10 41.2 0.7 1.5 1 0 0 1 1 1 1 HMG-box domain Zip PF02535.17 KFP01475.1 - 1.2e-26 93.4 0.4 1.9e-26 92.8 0.3 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter 7tm_1 PF00001.16 KFP01476.1 - 3.5e-68 229.5 20.7 4.4e-68 229.2 14.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP01476.1 - 6.2e-17 61.6 21.5 7.7e-17 61.3 14.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP01476.1 - 2e-11 43.5 8.9 2e-11 43.5 6.2 2.1 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFP01476.1 - 2.6e-08 33.3 18.9 2.6e-08 33.3 13.1 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Herpes_US9 PF06072.6 KFP01476.1 - 0.16 11.8 0.1 0.16 11.8 0.1 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF1385 PF07136.6 KFP01476.1 - 2.5 7.1 10.8 0.04 12.9 0.6 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1385) FAM104 PF15434.1 KFP01478.1 - 1.3e-45 154.1 11.1 1.8e-45 153.6 7.7 1.2 1 0 0 1 1 1 1 Family 104 DUF566 PF04484.7 KFP01478.1 - 2 7.8 11.5 2.3 7.6 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SR-25 PF10500.4 KFP01478.1 - 2.3 7.6 18.0 3.5 7.0 12.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WRW PF10206.4 KFP01479.1 - 4.3e-12 45.9 0.0 4.6e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f BORG_CEP PF14957.1 KFP01480.1 - 1.9e-36 125.6 0.3 4e-36 124.6 0.2 1.5 1 0 0 1 1 1 1 Cdc42 effector PBD PF00786.23 KFP01480.1 - 1.5e-09 38.1 0.2 1.1e-08 35.2 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain fn3 PF00041.16 KFP01481.1 - 1.3e-174 566.8 36.0 6.1e-15 55.1 0.2 14.0 14 0 0 14 14 14 13 Fibronectin type III domain I-set PF07679.11 KFP01481.1 - 1.4e-67 223.6 0.0 4.5e-15 55.2 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP01481.1 - 1.2e-53 179.1 0.0 1.1e-09 38.2 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFP01481.1 - 5.4e-35 119.6 2.2 3e-07 30.8 0.0 9.4 8 0 0 8 8 8 6 Immunoglobulin domain ig PF00047.20 KFP01481.1 - 9.7e-32 108.9 0.0 1.8e-06 27.9 0.0 7.0 6 0 0 6 6 6 5 Immunoglobulin domain V-set PF07686.12 KFP01481.1 - 1.2e-21 76.6 0.0 0.00053 19.8 0.0 7.6 6 2 0 6 6 6 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP01481.1 - 7.9e-13 48.1 0.2 0.3 11.0 0.0 6.1 6 0 0 6 6 6 4 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.5 KFP01481.1 - 1e-08 35.1 0.0 0.36 10.8 0.0 6.2 6 0 0 6 6 6 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFP01481.1 - 0.29 10.8 10.4 2.1 8.1 0.0 6.2 6 0 0 6 6 6 0 Tissue factor Ribosomal_L38e PF01781.13 KFP01482.1 - 7e-22 76.9 1.5 7.3e-22 76.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Tweety PF04906.8 KFP01483.1 - 1.2e-123 412.5 7.7 1.3e-123 412.4 5.3 1.0 1 0 0 1 1 1 1 Tweety Tetraspannin PF00335.15 KFP01483.1 - 0.00015 21.1 5.1 0.00034 19.9 2.4 2.0 2 0 0 2 2 2 1 Tetraspanin family DUF4131 PF13567.1 KFP01483.1 - 0.008 15.6 9.1 0.14 11.5 5.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) WD40 PF00400.27 KFP01484.1 - 1.6e-05 24.5 12.4 0.3 11.0 0.4 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat RseA_C PF03873.8 KFP01485.1 - 0.38 10.6 3.1 1.1 9.2 2.2 1.7 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Oxidored-like PF09791.4 KFP01486.1 - 6.8e-06 25.4 5.2 9.2e-06 24.9 3.6 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal PDE6_gamma PF04868.7 KFP01487.1 - 3.1e-51 171.1 0.4 3.7e-51 170.8 0.3 1.0 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit NPL4 PF05021.10 KFP01488.1 - 9.7e-89 297.5 0.1 9.6e-86 287.7 0.0 2.5 2 0 0 2 2 2 2 NPL4 family zf-NPL4 PF05020.10 KFP01488.1 - 1.8e-59 199.6 0.4 3e-59 198.8 0.3 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KFP01488.1 - 3.4e-32 110.5 0.1 6.1e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 FANCAA PF15146.1 KFP01489.1 - 1.2e-136 456.1 0.5 1.3e-136 455.9 0.3 1.0 1 0 0 1 1 1 1 Fanconi anemia-associated FANCAA PF15146.1 KFP01490.1 - 7.2e-50 170.1 1.1 7.9e-50 170.0 0.8 1.0 1 0 0 1 1 1 1 Fanconi anemia-associated Actin PF00022.14 KFP01491.1 - 6.8e-143 475.8 0.0 7.9e-143 475.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFP01491.1 - 0.11 12.8 0.1 0.32 11.3 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PBP1_TM PF14812.1 KFP01494.1 - 1.3 9.3 3.7 2 8.7 2.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ENTH PF01417.15 KFP01495.1 - 6.5e-07 29.2 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 ENTH domain IQ PF00612.22 KFP01496.1 - 0.0064 16.0 3.6 0.032 13.8 2.5 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif IMD PF08397.6 KFP01498.1 - 7.9e-95 316.2 7.5 1.1e-94 315.8 5.2 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.1 KFP01498.1 - 4.2e-10 39.0 0.0 7.4e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP01498.1 - 7.6e-08 31.7 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP01498.1 - 1.1e-05 24.7 0.0 2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Exonuc_VII_L PF02601.10 KFP01498.1 - 1.1 8.4 6.2 1.5 7.9 4.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snf7 PF03357.16 KFP01499.1 - 1.3e-37 128.8 15.5 1.5e-37 128.6 10.8 1.0 1 0 0 1 1 1 1 Snf7 DUF1675 PF07897.6 KFP01499.1 - 0.061 13.1 0.2 0.075 12.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4635 PF15466.1 KFP01499.1 - 0.075 12.3 3.2 0.08 12.2 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) Gluconate_2-dh3 PF13618.1 KFP01499.1 - 0.081 13.0 1.5 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DIRP PF06584.8 KFP01499.1 - 0.65 9.8 3.8 1.3 8.9 2.6 1.6 1 0 0 1 1 1 0 DIRP EMP24_GP25L PF01105.19 KFP01499.1 - 5 6.7 6.2 0.7 9.5 1.4 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Raptor_N PF14538.1 KFP01500.1 - 4.8e-75 250.5 0.0 9.9e-75 249.5 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 KFP01500.1 - 2.2e-15 55.3 1.7 0.00019 21.2 0.0 6.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 KFP01500.1 - 4.4e-11 42.9 0.5 5.9e-06 26.4 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats WD40 PF00400.27 KFP01500.1 - 1.7e-09 37.1 20.1 0.0046 16.7 0.1 7.2 9 0 0 9 9 9 3 WD domain, G-beta repeat Cnd1 PF12717.2 KFP01500.1 - 2.7e-06 27.3 0.3 0.1 12.4 0.0 3.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFP01500.1 - 1.2e-05 25.6 0.6 0.12 12.8 0.0 4.2 4 0 0 4 4 4 2 HEAT-like repeat Arm PF00514.18 KFP01500.1 - 0.011 15.5 0.1 0.18 11.6 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 KFP01500.1 - 0.02 14.7 0.0 0.95 9.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 KFP01500.1 - 0.21 9.8 0.0 0.83 7.8 0.0 1.8 1 1 0 1 1 1 0 Adaptin N terminal region Pentaxin PF00354.12 KFP01501.1 - 3.8e-36 124.3 0.0 5.9e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFP01501.1 - 3.1e-16 59.9 0.1 4.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 KFP01501.1 - 0.0092 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Mod_r PF07200.8 KFP01501.1 - 0.067 13.1 14.2 0.47 10.3 3.6 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF16 PF01519.11 KFP01501.1 - 0.098 12.8 0.3 0.098 12.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.7 KFP01501.1 - 0.27 11.6 10.9 0.17 12.2 0.3 3.8 2 1 2 4 4 4 0 SlyX DUF1395 PF07160.7 KFP01501.1 - 0.98 8.8 6.5 0.088 12.2 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) Syntaxin-6_N PF09177.6 KFP01501.1 - 1.7 9.0 8.7 0.72 10.2 0.5 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Pox_A_type_inc PF04508.7 KFP01501.1 - 2.1 8.3 7.6 64 3.7 0.1 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF848 PF05852.6 KFP01501.1 - 5.5 6.8 8.3 0.24 11.2 1.7 1.7 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FliJ PF02050.11 KFP01501.1 - 8.5 6.4 7.2 10 6.2 1.0 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Endonuclease_5 PF04493.9 KFP01502.1 - 4.6e-57 192.7 0.0 5.4e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V CtaG_Cox11 PF04442.9 KFP01503.1 - 0.13 12.1 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 Sulfatase PF00884.18 KFP01504.1 - 7.7e-50 169.8 0.0 1.7e-49 168.6 0.0 1.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFP01504.1 - 8.4e-12 45.0 0.0 5.3e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KFP01504.1 - 0.058 13.6 0.7 0.14 12.4 0.5 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 KFP01504.1 - 0.091 11.5 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Glyco_hydro_31 PF01055.21 KFP01505.1 - 1.1e-148 495.7 0.0 1e-73 248.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFP01505.1 - 4.5e-09 36.0 0.0 1.3e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like BRE1 PF08647.6 KFP01506.1 - 7.1e-15 54.7 16.8 7.1e-15 54.7 11.6 11.5 4 3 8 13 13 13 2 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 KFP01506.1 - 2.7 7.0 31.7 0.11 11.6 0.5 5.5 2 1 2 6 6 6 0 Reovirus sigma C capsid protein Chromo PF00385.19 KFP01508.1 - 9.2e-12 44.4 0.7 9.2e-12 44.4 0.5 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain VirC1 PF07015.6 KFP01508.1 - 0.18 10.8 0.2 0.28 10.2 0.2 1.2 1 0 0 1 1 1 0 VirC1 protein Fox-1_C PF12414.3 KFP01510.1 - 4.7e-37 126.2 16.4 4.7e-37 126.2 11.4 2.6 3 0 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 KFP01510.1 - 4.1e-19 67.9 1.0 5.2e-19 67.6 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP01510.1 - 6.9e-15 54.7 0.1 1.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP01510.1 - 2.7e-10 39.9 0.1 5.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP01510.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_85 PF03644.8 KFP01511.1 - 5.2e-94 314.8 0.0 6.5e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 C1q PF00386.16 KFP01512.1 - 2.5e-37 127.6 1.8 3.1e-37 127.3 1.2 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP01512.1 - 1.3e-08 34.2 13.1 1.9e-08 33.7 9.1 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Apyrase PF06079.6 KFP01513.1 - 7.3e-86 287.9 0.5 8.5e-86 287.7 0.3 1.0 1 0 0 1 1 1 1 Apyrase TIMP PF00965.12 KFP01514.1 - 4.2e-68 228.5 5.8 4.7e-68 228.3 4.0 1.0 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 KFP01514.1 - 0.00063 19.2 0.2 0.0015 18.0 0.0 1.8 1 1 1 2 2 2 1 UNC-6/NTR/C345C module UCH PF00443.24 KFP01515.1 - 2e-52 177.9 0.2 2.4e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP01515.1 - 6.5e-22 78.3 0.0 8.7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2544 PF11245.3 KFP01515.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) Peptidase_C98 PF15499.1 KFP01515.1 - 0.31 10.2 2.1 1.8 7.7 1.5 2.2 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2197 PF09963.4 KFP01515.1 - 1.7 8.6 6.7 4.1 7.4 0.2 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) Seryl_tRNA_N PF02403.17 KFP01516.1 - 0.014 15.3 0.2 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MMgT PF10270.4 KFP01516.1 - 0.047 14.1 0.6 0.056 13.8 0.4 1.3 1 1 0 1 1 1 0 Membrane magnesium transporter MiaE PF06175.6 KFP01516.1 - 0.11 11.8 0.1 0.12 11.7 0.1 1.0 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) DUF4519 PF15012.1 KFP01516.1 - 0.12 12.2 1.5 0.16 11.9 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Sec7 PF01369.15 KFP01517.1 - 1.3e-70 236.9 0.1 2e-70 236.3 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KFP01517.1 - 2.2e-25 88.8 0.0 4e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP01517.1 - 3e-07 30.6 0.6 1.8e-06 28.1 0.4 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain BBS2_C PF14782.1 KFP01517.1 - 0.0015 17.1 1.4 0.12 10.9 0.7 2.1 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, C-terminal PH_3 PF14593.1 KFP01517.1 - 0.0024 17.7 0.2 0.015 15.1 0.1 2.2 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 KFP01517.1 - 0.017 15.1 0.0 0.09 12.8 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DASH_Spc34 PF08657.5 KFP01517.1 - 0.036 13.7 1.4 0.065 12.8 1.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF342 PF03961.8 KFP01517.1 - 0.048 12.0 0.8 0.063 11.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFP01517.1 - 0.12 11.4 3.2 0.19 10.7 2.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KFP01517.1 - 0.2 11.4 5.8 1.5 8.6 3.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KFP01517.1 - 0.24 10.9 1.9 0.52 9.8 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KFP01517.1 - 0.26 10.8 1.6 0.43 10.1 1.1 1.3 1 0 0 1 1 1 0 IncA protein Fzo_mitofusin PF04799.8 KFP01517.1 - 0.3 10.4 1.8 0.6 9.4 1.2 1.4 1 0 0 1 1 1 0 fzo-like conserved region PLDc_2 PF13091.1 KFP01518.1 - 3.4e-14 52.6 0.0 3.2e-06 26.8 0.0 3.0 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 KFP01518.1 - 0.052 13.3 3.3 0.35 10.7 0.2 2.9 3 0 0 3 3 3 0 Phospholipase D Active site motif SH2 PF00017.19 KFP01519.1 - 2.8e-10 39.8 0.0 5.8e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 KFP01519.1 - 2.4e-08 33.6 0.0 4.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 SOCS box Abhydrolase_3 PF07859.8 KFP01520.1 - 7.2e-18 64.9 2.9 1.2e-17 64.1 2.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFP01520.1 - 1.2e-09 38.0 0.5 1.6e-09 37.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFP01520.1 - 5.8e-07 28.5 0.2 9.3e-05 21.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.2 KFP01520.1 - 0.00011 22.2 2.3 0.00021 21.2 1.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFP01520.1 - 0.00089 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 KFP01520.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 KFP01520.1 - 0.003 17.0 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 KFP01520.1 - 0.0047 16.3 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 KFP01520.1 - 0.02 14.4 0.1 0.27 10.7 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KFP01520.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2235 PF09994.4 KFP01520.1 - 0.036 13.4 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) NYN PF01936.13 KFP01520.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 NYN domain TK PF00265.13 KFP01521.1 - 2.5e-63 212.8 0.3 3e-63 212.5 0.2 1.1 1 0 0 1 1 1 1 Thymidine kinase Arf PF00025.16 KFP01522.1 - 2.6e-18 65.8 0.0 3e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP01522.1 - 0.0013 18.1 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KFP01522.1 - 0.017 14.6 0.4 0.022 14.3 0.2 1.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein STAS_2 PF13466.1 KFP01522.1 - 0.13 12.3 1.3 1.6 8.8 0.2 2.2 2 0 0 2 2 2 0 STAS domain Ribosomal_L12 PF00542.14 KFP01523.1 - 7.5e-21 73.9 5.5 7.5e-21 73.9 3.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DUF4479 PF14794.1 KFP01523.1 - 0.051 13.1 1.3 0.11 12.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) Mito_carr PF00153.22 KFP01524.1 - 1.7e-57 191.1 1.4 7.6e-19 67.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FAM195 PF14799.1 KFP01525.1 - 5.7e-22 77.4 0.0 6.1e-22 77.3 0.0 1.0 1 0 0 1 1 1 1 FAM195 family Ank PF00023.25 KFP01526.1 - 6.8e-16 57.1 0.4 4.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFP01526.1 - 3.4e-15 56.1 0.0 4.1e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP01526.1 - 8.4e-14 51.6 0.1 1.1e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP01526.1 - 8.8e-14 51.2 0.9 1.1e-10 41.3 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01526.1 - 7.2e-10 38.1 0.3 0.00097 19.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Thioredoxin PF00085.15 KFP01527.1 - 5.3e-56 186.7 1.7 2.2e-26 91.5 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KFP01527.1 - 5.5e-50 169.7 5.2 4.1e-44 150.5 2.7 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFP01527.1 - 2.6e-12 46.9 1.0 4.9e-05 23.4 0.1 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFP01527.1 - 1.3e-10 41.1 0.0 0.00034 20.5 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KFP01527.1 - 2.5e-10 40.3 0.1 0.00015 21.7 0.0 4.5 4 1 1 5 5 5 2 Thioredoxin-like ERp29_N PF07912.8 KFP01527.1 - 2.5e-07 30.6 0.6 0.62 9.9 0.0 3.6 3 0 0 3 3 3 3 ERp29, N-terminal domain AhpC-TSA PF00578.16 KFP01527.1 - 7.7e-06 25.5 1.3 0.23 11.1 0.1 3.6 2 1 1 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KFP01527.1 - 9.8e-05 21.9 1.7 0.061 12.8 0.0 3.3 2 1 1 3 3 3 1 Redoxin Thioredoxin_9 PF14595.1 KFP01527.1 - 0.0075 15.8 0.1 2.1 7.8 0.1 2.8 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 KFP01527.1 - 0.015 15.1 0.0 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.19 KFP01527.1 - 0.031 14.2 1.4 2.5 8.1 0.0 3.5 3 1 0 3 3 3 0 Glutaredoxin HyaE PF07449.6 KFP01527.1 - 0.045 13.6 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 KFP01527.1 - 0.062 13.3 0.2 4.3 7.3 0.0 3.2 2 1 1 3 3 3 0 Thioredoxin Rho_GDI PF02115.12 KFP01528.1 - 5e-96 319.8 0.4 5.6e-96 319.6 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor RRM_1 PF00076.17 KFP01529.1 - 3.5e-09 36.1 0.0 5.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP01529.1 - 3.9e-08 33.0 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP01529.1 - 4.2e-07 29.8 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KFP01529.1 - 7.7e-07 29.4 10.1 2.1e-06 28.0 7.0 1.8 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 CTP_transf_2 PF01467.21 KFP01530.1 - 1.2e-28 100.1 0.0 7.3e-15 55.3 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 KFP01530.1 - 0.0048 16.5 0.1 0.045 13.3 0.0 2.1 2 0 0 2 2 2 1 FAD synthetase CHAP PF05257.11 KFP01530.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 CHAP domain SIR2 PF02146.12 KFP01531.1 - 2.6e-28 98.9 1.8 2.6e-22 79.4 0.5 2.1 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 KFP01531.1 - 0.00046 19.9 0.0 0.5 10.1 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain bZIP_Maf PF03131.12 KFP01532.1 - 9.1e-34 115.6 11.7 1.2e-33 115.3 8.1 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 KFP01532.1 - 8.4e-05 21.9 5.8 8.4e-05 21.9 4.0 2.2 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 KFP01532.1 - 0.0009 19.1 16.1 0.013 15.4 11.2 2.3 1 1 0 1 1 1 1 bZIP transcription factor ERM PF00769.14 KFP01532.1 - 0.001 18.6 3.6 0.0012 18.4 2.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2046 PF09755.4 KFP01532.1 - 0.0041 16.0 1.1 0.0041 16.0 0.8 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF1192 PF06698.6 KFP01532.1 - 0.0047 16.7 7.6 0.052 13.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF972 PF06156.8 KFP01532.1 - 0.012 15.8 3.7 0.012 15.8 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF342 PF03961.8 KFP01532.1 - 0.013 13.9 5.0 0.016 13.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFP01532.1 - 0.013 14.6 7.4 0.015 14.3 5.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Tox-ODYAM1 PF15642.1 KFP01532.1 - 0.028 13.0 3.4 0.035 12.7 2.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Spc24 PF08286.6 KFP01532.1 - 0.035 13.8 1.2 0.035 13.8 0.8 1.6 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 HTH_Crp_2 PF13545.1 KFP01532.1 - 0.06 13.1 0.4 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HALZ PF02183.13 KFP01532.1 - 0.066 12.9 9.1 0.074 12.7 2.4 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4164 PF13747.1 KFP01532.1 - 0.11 12.6 8.4 0.25 11.4 5.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) AAA_13 PF13166.1 KFP01532.1 - 0.15 10.4 2.9 0.18 10.1 2.0 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 KFP01532.1 - 0.18 10.6 8.4 0.22 10.4 5.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FimP PF09766.4 KFP01532.1 - 0.18 10.8 5.3 0.23 10.4 3.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein HGTP_anticodon2 PF12745.2 KFP01532.1 - 0.2 10.7 3.6 0.28 10.2 2.5 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs bZIP_2 PF07716.10 KFP01532.1 - 0.21 11.4 16.9 0.06 13.1 8.0 2.6 1 1 2 3 3 3 0 Basic region leucine zipper IncA PF04156.9 KFP01532.1 - 0.23 11.0 12.1 0.041 13.4 3.8 2.0 1 1 1 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 KFP01532.1 - 0.25 11.1 11.9 0.05 13.4 3.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Kinesin-relat_1 PF12711.2 KFP01532.1 - 0.28 11.5 7.5 0.068 13.5 2.1 2.0 2 0 0 2 2 2 0 Kinesin motor DUF3584 PF12128.3 KFP01532.1 - 0.34 8.1 8.1 0.38 8.0 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rop-like PF05082.8 KFP01532.1 - 0.38 10.2 3.7 0.19 11.2 0.6 2.0 2 0 0 2 2 2 0 Rop-like Mnd1 PF03962.10 KFP01532.1 - 0.5 10.0 7.6 0.71 9.5 5.3 1.3 1 0 0 1 1 1 0 Mnd1 family DUF1043 PF06295.7 KFP01532.1 - 0.51 9.9 3.4 0.51 9.9 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Nnf1 PF03980.9 KFP01532.1 - 0.63 10.0 7.1 2.1 8.3 4.9 1.8 1 1 0 1 1 1 0 Nnf1 V_ATPase_I PF01496.14 KFP01532.1 - 0.7 7.6 2.5 0.81 7.4 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.3 KFP01532.1 - 0.84 8.9 8.8 1.9 7.8 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DASH_Spc19 PF08287.6 KFP01532.1 - 1.1 8.8 10.1 1.6 8.3 7.0 1.2 1 0 0 1 1 1 0 Spc19 NUDE_C PF04880.8 KFP01532.1 - 1.4 9.2 8.3 2.6 8.3 0.7 2.1 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region NYD-SP28_assoc PF14775.1 KFP01532.1 - 2.1 8.0 6.0 0.69 9.6 1.4 2.3 2 1 1 3 3 3 0 Sperm tail C-terminal domain Mst1_SARAH PF11629.3 KFP01532.1 - 2.5 8.0 9.5 15 5.4 1.9 3.0 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Seryl_tRNA_N PF02403.17 KFP01532.1 - 2.6 8.0 9.8 4.3 7.4 6.6 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 KFP01532.1 - 3 8.1 5.9 3.8 7.7 4.1 1.2 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 KFP01532.1 - 3.2 8.2 9.7 2 8.9 2.9 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.9 KFP01532.1 - 3.3 7.2 9.3 6.7 6.2 6.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF465 PF04325.8 KFP01532.1 - 3.4 7.4 8.1 7.7 6.3 0.1 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF465) DUF3086 PF11285.3 KFP01532.1 - 5.1 5.8 7.1 2.3 6.9 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DUF904 PF06005.7 KFP01532.1 - 5.2 7.4 13.3 44 4.4 9.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) OmpH PF03938.9 KFP01532.1 - 5.9 6.8 11.7 10 6.0 8.1 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Bap31 PF05529.7 KFP01532.1 - 6.8 6.0 9.5 10 5.5 6.6 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like P5CR_dimer PF14748.1 KFP01533.1 - 1.3e-39 134.5 0.0 2.2e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KFP01533.1 - 2.2e-08 34.4 0.0 4.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KFP01533.1 - 0.00075 19.2 0.1 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KFP01533.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MARVEL PF01284.18 KFP01534.1 - 2e-23 82.8 47.3 5e-13 49.0 12.0 2.1 2 0 0 2 2 2 2 Membrane-associating domain PAE PF03283.8 KFP01535.1 - 1.3e-77 260.9 0.1 1.5e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase UPF0180 PF03698.8 KFP01535.1 - 0.14 11.9 0.1 21 5.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) UBX PF00789.15 KFP01536.1 - 9e-12 44.8 0.1 1.1e-06 28.5 0.0 2.7 2 0 0 2 2 2 2 UBX domain TUG-UBL1 PF11470.3 KFP01536.1 - 4.2e-07 29.7 0.1 8.4e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG LRR_6 PF13516.1 KFP01537.1 - 3.1e-08 32.8 12.0 0.089 12.9 0.1 5.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 KFP01537.1 - 9.9e-07 27.9 2.1 2.9 8.2 0.3 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.2 KFP01537.1 - 1e-05 25.0 12.2 0.032 13.8 3.0 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP01537.1 - 0.00021 20.9 12.2 0.017 14.8 0.9 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 KFP01537.1 - 0.0029 17.5 6.8 23 5.7 0.1 5.8 5 0 0 5 5 5 0 Leucine rich repeat Baculo_PEP_C PF04513.7 KFP01537.1 - 2 8.2 30.7 0.19 11.5 2.5 4.4 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KFP01537.1 - 6.7 6.5 37.7 2.3 8.0 2.8 5.3 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 KFP01537.1 - 9.1 6.6 30.0 3.8 7.8 0.6 6.2 4 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Ras PF00071.17 KFP01538.1 - 3.8e-50 169.4 0.0 4.3e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01538.1 - 4.9e-13 49.6 0.0 6.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP01538.1 - 3.5e-05 23.1 0.0 4.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family adh_short_C2 PF13561.1 KFP01539.1 - 2.8e-21 76.3 0.2 2.9e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFP01539.1 - 8.1e-08 32.3 0.6 3.5e-07 30.3 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NosL PF05573.7 KFP01539.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 NosL Fringe PF02434.11 KFP01540.1 - 1.1e-117 391.7 0.0 1.3e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Glyco_transf_21 PF13506.1 KFP01540.1 - 0.016 14.4 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 Galactosyl_T PF01762.16 KFP01540.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase Glyco_tranf_2_3 PF13641.1 KFP01540.1 - 0.021 14.6 0.1 0.046 13.5 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFP01540.1 - 0.088 12.4 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 RPN7 PF10602.4 KFP01541.1 - 5.3e-68 227.8 1.2 9.3e-68 227.0 0.8 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFP01541.1 - 2.1e-17 63.3 1.2 8.8e-17 61.3 0.1 2.3 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 KFP01541.1 - 0.0014 18.2 0.2 0.18 11.4 0.0 2.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFP01541.1 - 0.0038 17.0 4.6 0.15 12.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP01541.1 - 0.078 12.6 5.2 0.16 11.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Dus PF01207.12 KFP01542.1 - 9.8e-57 192.1 0.1 1.5e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF702 PF05142.7 KFP01542.1 - 0.0003 21.0 7.5 0.00059 20.0 5.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF702) His_biosynth PF00977.16 KFP01542.1 - 0.00039 19.7 0.0 0.00059 19.1 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.16 KFP01542.1 - 0.017 14.0 0.0 0.098 11.6 0.0 2.0 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Ribosomal_S14 PF00253.16 KFP01542.1 - 0.019 14.3 1.9 0.049 13.0 1.3 1.7 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e TMP-TENI PF02581.12 KFP01542.1 - 0.025 13.7 0.1 0.06 12.4 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI ThiG PF05690.9 KFP01542.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Acyl_transf_1 PF00698.16 KFP01543.1 - 1.3e-101 340.1 0.0 2.4e-101 339.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KFP01543.1 - 5.3e-74 248.8 0.0 8.7e-74 248.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.15 KFP01543.1 - 4.1e-54 184.2 0.1 3.9e-52 177.7 0.0 2.9 3 0 0 3 3 3 1 Thioesterase domain KR PF08659.5 KFP01543.1 - 9.1e-49 165.5 0.0 5e-48 163.1 0.0 2.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KFP01543.1 - 2.5e-47 160.8 0.2 7.8e-46 156.0 0.0 3.2 3 1 1 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFP01543.1 - 9.1e-33 112.6 0.0 2.5e-32 111.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KFP01543.1 - 1.4e-21 76.9 0.0 2.5e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 KFP01543.1 - 2.6e-19 69.0 1.8 2.8e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KFP01543.1 - 1.1e-09 38.3 0.6 2.9e-09 37.0 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 KFP01543.1 - 2.4e-09 38.1 0.1 1e-08 36.1 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 KFP01543.1 - 0.00015 20.8 0.0 0.00041 19.4 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain YjeF_N PF03853.10 KFP01543.1 - 0.0028 17.2 0.1 1.4 8.4 0.0 3.9 4 0 0 4 4 4 1 YjeF-related protein N-terminus Methyltransf_23 PF13489.1 KFP01543.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.5 KFP01543.1 - 0.012 15.3 0.2 0.056 13.0 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2332 PF10094.4 KFP01544.1 - 0.066 12.1 0.1 0.078 11.9 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) PEP-utilisers_N PF05524.8 KFP01545.1 - 0.0017 18.1 0.3 0.0017 18.1 0.2 1.0 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal HALZ PF02183.13 KFP01545.1 - 0.011 15.3 2.2 0.02 14.6 1.3 1.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF3450 PF11932.3 KFP01545.1 - 0.013 14.7 1.1 0.013 14.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 KFP01545.1 - 0.013 15.2 1.9 0.015 15.1 1.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 KFP01545.1 - 0.014 15.4 0.7 0.015 15.3 0.5 1.1 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.10 KFP01545.1 - 0.015 14.7 0.6 0.015 14.7 0.4 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4631 PF15450.1 KFP01545.1 - 0.016 13.5 1.2 0.017 13.4 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) MbeD_MobD PF04899.7 KFP01545.1 - 0.023 14.6 1.9 0.036 13.9 1.4 1.3 1 1 0 1 1 1 0 MbeD/MobD like bZIP_1 PF00170.16 KFP01545.1 - 0.067 13.1 1.0 0.078 12.9 0.7 1.2 1 0 0 1 1 1 0 bZIP transcription factor NTR2 PF15458.1 KFP01545.1 - 0.069 12.3 1.4 0.069 12.3 1.0 1.0 1 0 0 1 1 1 0 Nineteen complex-related protein 2 bZIP_2 PF07716.10 KFP01545.1 - 0.095 12.5 1.2 0.095 12.5 0.8 1.6 1 1 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 KFP01545.1 - 0.2 11.3 1.8 0.21 11.2 0.4 1.8 1 1 1 2 2 2 0 Sperm tail C-terminal domain MFS_1 PF07690.11 KFP01546.1 - 1.1e-35 122.9 44.9 7.1e-34 117.0 19.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFP01546.1 - 0.00024 20.8 6.5 0.24 11.2 0.1 3.7 3 0 0 3 3 3 2 MFS_1 like family Pkinase PF00069.20 KFP01547.1 - 3.5e-31 108.3 0.0 4.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01547.1 - 1e-12 47.7 0.0 1.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP01547.1 - 8.8e-05 22.3 0.0 0.00063 19.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFP01547.1 - 0.027 13.2 0.2 0.038 12.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_M10 PF00413.19 KFP01548.1 - 2.9e-59 199.2 0.0 3.9e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 KFP01548.1 - 6.4e-11 42.0 0.1 6e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFP01548.1 - 2.1e-05 24.0 0.9 0.1 11.9 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M54 PF07998.6 KFP01548.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Metallopep PF12044.3 KFP01548.1 - 0.042 12.2 0.0 0.067 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.1 KFP01548.1 - 0.057 13.4 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFP01548.1 - 0.085 13.3 0.4 0.16 12.5 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP01548.1 - 0.099 12.1 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KFP01548.1 - 0.11 11.4 0.1 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.1 KFP01548.1 - 0.15 11.9 0.2 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Pkinase_Tyr PF07714.12 KFP01549.1 - 2.7e-37 128.2 0.0 3.8e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP01549.1 - 3.5e-36 124.6 0.0 5.6e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CARD PF00619.16 KFP01549.1 - 3.4e-18 65.2 0.4 8.4e-18 64.0 0.3 1.6 1 0 0 1 1 1 1 Caspase recruitment domain APH PF01636.18 KFP01549.1 - 0.082 12.6 0.3 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease_2 PF13520.1 KFP01550.1 - 4.7e-65 219.7 35.6 5.8e-65 219.4 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFP01550.1 - 7.2e-27 93.8 33.4 9.7e-27 93.4 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2304 PF10066.4 KFP01550.1 - 0.069 12.9 0.3 0.069 12.9 0.2 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Pyr_redox_3 PF13738.1 KFP01552.1 - 4.1e-07 30.2 0.1 1.9e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFP01552.1 - 0.0021 17.9 0.0 0.12 12.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Nbs1_C PF08599.5 KFP01553.1 - 5.8e-37 125.4 0.2 2.2e-36 123.5 0.1 2.1 1 0 0 1 1 1 1 DNA damage repair protein Nbs1 FHA PF00498.21 KFP01553.1 - 2.7e-14 53.0 0.1 6.6e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KFP01553.1 - 1.3e-10 41.2 0.1 8.2e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFP01553.1 - 8.6e-05 22.3 0.2 0.00018 21.2 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain Chisel PF15355.1 KFP01553.1 - 0.16 11.9 2.8 1.3 9.0 0.2 3.2 3 0 0 3 3 3 0 Stretch-responsive small skeletal muscle X protein, Chisel EF-hand_1 PF00036.27 KFP01554.1 - 1.8e-23 80.0 10.4 1.3e-07 30.4 0.7 5.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KFP01554.1 - 8.5e-23 78.1 9.7 2e-07 30.3 0.4 5.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KFP01554.1 - 6.2e-22 77.5 7.4 1.9e-10 40.7 1.3 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFP01554.1 - 1e-14 53.0 7.1 0.00019 20.6 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFP01554.1 - 1.5e-08 34.1 9.3 2.9e-06 26.8 0.5 3.2 4 1 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP01554.1 - 0.0014 18.6 2.8 1.1 9.3 0.0 3.3 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.6 KFP01554.1 - 0.003 17.5 7.2 0.65 10.0 0.1 3.4 3 1 0 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like DUF4299 PF14132.1 KFP01554.1 - 0.003 16.7 1.0 0.0069 15.5 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4299) EF-hand_3 PF09069.6 KFP01554.1 - 0.0093 16.0 0.2 1 9.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand LXG PF04740.7 KFP01554.1 - 0.016 14.9 5.6 0.48 10.1 0.5 2.9 2 1 1 3 3 3 0 LXG domain of WXG superfamily EF-hand_10 PF14788.1 KFP01554.1 - 0.028 14.0 9.4 2.1 8.0 0.3 4.3 3 1 1 4 4 4 0 EF hand SUKH_5 PF14567.1 KFP01554.1 - 0.075 12.4 1.2 0.28 10.6 0.0 2.5 3 1 1 4 4 4 0 SMI1-KNR4 cell-wall UPF0158 PF03682.8 KFP01554.1 - 0.16 11.5 5.2 0.22 11.1 0.1 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0158) RE_Eco47II PF09553.5 KFP01554.1 - 0.18 10.9 2.7 5.6 6.0 0.2 2.4 2 0 0 2 2 2 0 Eco47II restriction endonuclease ApoLp-III PF07464.6 KFP01554.1 - 0.62 10.0 3.9 8.4 6.4 0.1 2.7 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) SYCE1 PF15233.1 KFP01554.1 - 1.5 8.7 7.8 42 4.0 5.4 2.3 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 ABM PF03992.11 KFP01555.1 - 4e-08 33.1 0.1 7.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EF-hand_1 PF00036.27 KFP01555.1 - 8.1e-06 24.7 0.7 0.053 12.8 0.0 2.8 1 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFP01555.1 - 1.4e-05 24.6 1.9 0.00061 19.3 1.4 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KFP01555.1 - 3.9e-05 23.7 3.3 0.0035 17.4 0.5 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP01555.1 - 4.8e-05 22.9 0.4 0.015 15.1 0.1 2.9 1 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KFP01555.1 - 0.0032 16.7 0.9 0.21 11.0 0.0 3.1 2 1 1 3 3 3 1 EF hand RraB PF06877.6 KFP01555.1 - 0.0042 17.7 0.3 0.014 16.0 0.2 1.9 1 0 0 1 1 1 1 Regulator of ribonuclease activity B DUF904 PF06005.7 KFP01555.1 - 0.0089 16.3 1.0 0.0089 16.3 0.7 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF904) DUF4254 PF14063.1 KFP01555.1 - 0.03 13.9 0.2 0.074 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) MRP-L28 PF09812.4 KFP01555.1 - 0.043 13.6 0.2 0.043 13.6 0.2 2.1 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L28 Exonuc_VII_S PF02609.11 KFP01555.1 - 0.081 12.7 7.7 1.1 9.1 0.3 3.5 2 1 1 3 3 3 0 Exonuclease VII small subunit TerB PF05099.8 KFP01555.1 - 0.088 12.5 0.0 0.23 11.1 0.0 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TerB EF-hand_10 PF14788.1 KFP01555.1 - 0.14 11.8 1.4 2.9 7.6 0.4 3.3 3 1 0 3 3 3 0 EF hand AAA_23 PF13476.1 KFP01555.1 - 0.45 10.8 9.7 5.9 7.1 1.2 2.2 1 1 1 2 2 2 0 AAA domain AF0941-like PF14591.1 KFP01555.1 - 1.6 8.7 9.5 3.6 7.6 0.3 3.4 2 1 1 3 3 3 0 AF0941-like DUF1664 PF07889.7 KFP01555.1 - 2.1 8.1 4.6 0.8 9.5 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YojJ PF10372.4 KFP01555.1 - 2.3 8.1 5.4 16 5.4 0.2 3.2 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus eIF_4EBP PF05456.6 KFP01556.1 - 0.018 14.6 0.1 0.018 14.6 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Tmemb_55A PF09788.4 KFP01557.1 - 2.2e-104 348.1 18.2 2.5e-104 347.9 12.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A PhnA_Zn_Ribbon PF08274.7 KFP01557.1 - 0.004 16.9 1.9 7.3 6.4 0.3 3.7 3 1 0 3 3 3 1 PhnA Zinc-Ribbon zf-CHY PF05495.7 KFP01557.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.9 2 1 0 2 2 2 0 CHY zinc finger zf-BED PF02892.10 KFP01557.1 - 0.33 10.7 13.4 0.54 10.0 0.0 3.9 3 1 2 5 5 5 0 BED zinc finger Zn-ribbon_8 PF09723.5 KFP01557.1 - 0.33 10.9 0.2 0.33 10.9 0.2 3.0 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 KFP01557.1 - 0.36 10.4 0.0 0.36 10.4 0.0 4.8 5 1 1 6 6 6 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFP01557.1 - 0.36 10.5 0.0 0.36 10.5 0.0 4.8 5 1 1 6 6 6 0 zinc-ribbon domain IBR PF01485.16 KFP01557.1 - 0.46 10.4 20.6 1.8 8.5 0.3 3.8 2 1 2 4 4 4 0 IBR domain zf-RING_3 PF14369.1 KFP01557.1 - 1.8 8.6 0.0 1.8 8.6 0.0 3.7 4 0 0 4 4 4 0 zinc-finger OTU PF02338.14 KFP01558.1 - 6.5e-23 81.6 0.0 6.5e-23 81.6 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFP01558.1 - 8.1e-10 38.4 0.1 2.4e-05 23.8 0.0 2.7 1 1 1 2 2 2 2 Peptidase C65 Otubain IFP_35_N PF07334.8 KFP01558.1 - 0.11 12.5 7.7 0.056 13.4 3.9 1.6 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Tox-ART-HYE1 PF15634.1 KFP01558.1 - 0.17 10.7 3.4 0.25 10.2 2.4 1.1 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase Vfa1 PF08432.5 KFP01558.1 - 0.82 9.6 10.6 1.2 9.1 7.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sulfate_transp PF00916.15 KFP01559.1 - 4.2e-60 203.1 8.4 4.2e-60 203.1 5.8 1.5 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFP01559.1 - 3e-25 87.7 2.5 3e-25 87.7 1.7 2.9 3 1 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif zf-LITAF-like PF10601.4 KFP01559.1 - 1 9.2 3.7 1.2 9.0 1.4 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain COesterase PF00135.23 KFP01561.1 - 2.8e-188 626.9 0.1 3.6e-188 626.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFP01561.1 - 8.6e-07 28.7 0.1 4.2e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sarcoglycan_2 PF05510.8 KFP01561.1 - 0.013 13.8 0.2 0.027 12.7 0.0 1.5 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon HAD_2 PF13419.1 KFP01562.1 - 4.5e-18 66.0 0.0 5.5e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFP01562.1 - 0.00016 22.1 0.0 0.00021 21.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFP01562.1 - 0.0086 16.2 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFP01562.1 - 0.028 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_6 PF13344.1 KFP01562.1 - 0.15 11.9 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Sulfatase PF00884.18 KFP01563.1 - 2.6e-93 312.6 0.0 3.2e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFP01563.1 - 3.9e-45 153.3 0.9 6.2e-45 152.6 0.6 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFP01563.1 - 6.1e-10 38.9 0.0 4.8e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Patatin PF01734.17 KFP01564.1 - 1.3e-15 57.8 0.6 3.2e-14 53.3 0.4 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase fn3 PF00041.16 KFP01565.1 - 6.2e-40 135.2 9.1 1.5e-14 53.8 0.1 4.3 4 0 0 4 4 4 4 Fibronectin type III domain WAP PF00095.16 KFP01565.1 - 2.1e-10 40.3 15.7 2.1e-10 40.3 10.9 2.7 2 1 0 2 2 2 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Interfer-bind PF09294.5 KFP01565.1 - 2.7e-05 24.1 0.9 0.0011 18.9 0.0 3.2 4 0 0 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III Vif PF00559.12 KFP01565.1 - 0.0086 15.9 0.1 0.062 13.1 0.0 2.3 2 0 0 2 2 2 1 Retroviral Vif (Viral infectivity) protein IFP_35_N PF07334.8 KFP01565.1 - 0.12 12.3 0.3 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus WD40 PF00400.27 KFP01567.1 - 6.2e-59 193.9 27.6 1.9e-13 49.7 0.2 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 KFP01567.1 - 2.1e-11 43.8 0.5 0.00075 19.2 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFP01567.1 - 0.0037 15.4 3.4 0.063 11.4 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 KFP01567.1 - 0.0073 14.1 0.5 0.06 11.1 0.3 2.3 1 1 0 1 1 1 1 IKI3 family K_channel_TID PF07941.6 KFP01567.1 - 0.14 12.3 5.7 0.29 11.4 3.9 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ocular_alb PF02101.10 KFP01569.1 - 6.9e-171 568.2 7.9 8.2e-171 568.0 5.5 1.0 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_2 PF00002.19 KFP01569.1 - 3.3e-05 23.0 9.1 7.5e-05 21.9 6.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) ASD2 PF08687.6 KFP01570.1 - 4.9e-112 373.5 22.5 4.9e-112 373.5 15.6 3.3 3 0 0 3 3 3 1 Apx/Shroom domain ASD2 ASD1 PF08688.5 KFP01570.1 - 6e-55 185.8 6.8 6e-55 185.8 4.7 5.0 5 0 0 5 5 5 2 Apx/Shroom domain ASD1 Claudin_2 PF13903.1 KFP01571.1 - 4.2e-10 39.5 6.7 5.5e-10 39.2 4.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP01571.1 - 3.7e-06 26.7 8.5 6.4e-06 25.9 5.9 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family FtsX PF02687.16 KFP01571.1 - 6.6 6.5 14.1 36 4.1 6.6 2.6 1 1 1 2 2 2 0 FtsX-like permease family Voltage_CLC PF00654.15 KFP01573.1 - 4.7e-102 341.6 17.4 4.7e-102 341.6 12.1 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFP01573.1 - 8.6e-16 57.4 0.7 5.2e-09 35.7 0.1 2.6 2 0 0 2 2 2 2 CBS domain SPRY PF00622.23 KFP01574.1 - 1.3e-18 67.2 0.0 2.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFP01574.1 - 6.4e-11 41.6 0.1 2.1e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 SPRY-associated domain zf-B_box PF00643.19 KFP01574.1 - 1.7e-08 34.2 0.8 1.7e-08 34.2 0.6 4.8 5 1 0 5 5 4 2 B-box zinc finger fn3 PF00041.16 KFP01574.1 - 2.8e-08 33.7 0.2 6.4e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.1 KFP01574.1 - 9e-08 31.6 7.6 9e-08 31.6 5.2 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP01574.1 - 3.7e-07 30.0 11.6 3.7e-07 30.0 8.0 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP01574.1 - 2.4e-06 27.3 12.3 2.4e-06 27.3 8.5 4.6 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFP01574.1 - 3e-06 26.7 11.6 3e-06 26.7 8.1 3.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP01574.1 - 5e-06 26.2 11.8 5e-06 26.2 8.2 3.3 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFP01574.1 - 0.00024 20.7 10.0 0.00024 20.7 7.0 3.7 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFP01574.1 - 0.00032 20.3 7.2 0.00032 20.3 5.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 KFP01574.1 - 0.17 11.8 1.2 0.78 9.7 0.2 2.6 2 1 0 2 2 2 0 U-box domain RhoGAP PF00620.22 KFP01575.1 - 8.3e-48 161.8 0.1 2.1e-47 160.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain DUF1679 PF07914.6 KFP01575.1 - 0.051 12.2 0.0 0.084 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) FERM_M PF00373.13 KFP01577.1 - 1.1e-21 77.2 0.1 2.9e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 FERM central domain WW PF00397.21 KFP01577.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 WW domain FERM_N PF09379.5 KFP01577.1 - 0.012 15.6 0.2 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 FERM N-terminal domain Pribosyl_synth PF14572.1 KFP01578.1 - 6.4e-45 153.1 1.9 2.3e-37 128.5 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFP01578.1 - 4.5e-33 113.4 0.7 1.9e-32 111.4 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFP01578.1 - 2e-10 40.4 0.8 7.7e-10 38.5 0.4 1.9 1 1 1 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFP01578.1 - 0.00013 21.2 0.1 0.0002 20.6 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase LRR_8 PF13855.1 KFP01579.1 - 4.6e-73 240.8 89.4 3.1e-11 42.8 3.0 14.7 9 4 7 16 16 16 16 Leucine rich repeat LRR_4 PF12799.2 KFP01579.1 - 4.9e-44 147.2 101.5 1.6e-06 27.5 2.1 16.3 6 4 12 18 18 18 16 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP01579.1 - 2.2e-28 93.9 87.1 0.021 14.7 0.5 23.8 23 3 1 24 24 24 11 Leucine Rich Repeat TIR PF01582.15 KFP01579.1 - 6.3e-20 71.0 0.2 1.1e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 TIR domain LRR_5 PF13306.1 KFP01579.1 - 1.1e-12 47.7 33.2 1.2e-05 24.9 0.1 7.3 5 1 1 7 7 7 5 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFP01579.1 - 1.1e-11 42.8 68.0 1.7 9.1 0.2 21.0 23 1 1 24 24 24 4 Leucine rich repeat LRR_9 PF14580.1 KFP01579.1 - 1.8e-06 27.6 21.7 0.063 12.8 2.0 7.1 4 2 1 7 7 7 2 Leucine-rich repeat TIR_2 PF13676.1 KFP01579.1 - 2.1e-05 24.5 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_6 PF13516.1 KFP01579.1 - 0.0014 18.4 84.5 1.5 9.1 0.2 20.2 21 2 1 22 22 22 2 Leucine Rich repeat LRRNT PF01462.13 KFP01579.1 - 0.31 10.5 0.0 0.31 10.5 0.0 4.5 5 0 0 5 5 5 0 Leucine rich repeat N-terminal domain Yae1_N PF09811.4 KFP01580.1 - 2.2e-13 49.4 35.8 27 4.4 24.8 3.3 1 1 0 1 1 1 1 Essential protein Yae1, N terminal MAM PF00629.18 KFP01581.1 - 3.2e-26 92.0 0.0 6.8e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 MAM domain EGF_CA PF07645.10 KFP01581.1 - 1.6e-23 82.4 39.6 4.1e-11 42.6 6.9 6.1 4 2 2 6 6 6 3 Calcium-binding EGF domain cEGF PF12662.2 KFP01581.1 - 6.5e-15 54.4 35.4 0.00019 20.9 0.1 5.8 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF_3 PF12947.2 KFP01581.1 - 5.7e-12 45.3 21.1 4.2e-10 39.4 7.6 6.2 5 1 0 5 5 5 3 EGF domain FXa_inhibition PF14670.1 KFP01581.1 - 1e-10 41.5 73.2 2.1e-06 27.7 5.2 5.7 4 1 1 5 5 5 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFP01581.1 - 3e-06 27.0 71.7 0.00083 19.2 4.7 5.8 5 0 0 5 5 5 4 EGF-like domain TFIIS_M PF07500.9 KFP01582.1 - 3.8e-29 101.0 0.8 3.8e-29 101.0 0.6 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 KFP01582.1 - 5.9e-10 38.4 0.1 1.5e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 KFP01582.1 - 0.01 15.4 5.0 0.015 14.9 0.1 2.8 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Ras PF00071.17 KFP01583.1 - 1.3e-57 193.6 0.0 1.5e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01583.1 - 6.2e-18 65.4 0.0 9e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP01583.1 - 5.7e-12 45.2 0.0 6.6e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP01583.1 - 6.4e-06 25.4 0.0 8.6e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP01583.1 - 6.6e-06 26.0 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP01583.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFP01583.1 - 0.0032 16.6 0.1 0.0082 15.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KFP01583.1 - 0.0042 16.5 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KFP01583.1 - 0.0082 15.7 0.2 0.057 12.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KFP01583.1 - 0.039 13.9 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KFP01583.1 - 0.063 13.4 0.0 0.2 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KFP01583.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 2 1 1 3 3 3 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 KFP01583.1 - 0.13 11.9 0.3 0.52 9.9 0.0 1.9 2 1 0 2 2 2 0 Archaeal ATPase Sedlin_N PF04628.8 KFP01584.1 - 1.7e-46 157.3 0.4 1.9e-46 157.2 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KFP01584.1 - 1.7e-09 37.4 0.1 2.2e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Sybindin-like family Pex14_N PF04695.8 KFP01584.1 - 0.025 14.6 0.1 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FOP_dimer PF09398.5 KFP01585.1 - 0.00042 20.2 0.9 0.31 11.0 0.0 4.1 3 0 0 3 3 3 1 FOP N terminal dimerisation domain LisH PF08513.6 KFP01585.1 - 0.012 15.3 0.1 0.037 13.7 0.0 2.0 2 0 0 2 2 2 0 LisH DUF3301 PF11743.3 KFP01585.1 - 0.54 9.8 4.3 1.6 8.2 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Myelin_PLP PF01275.14 KFP01586.1 - 4.7e-125 415.7 21.0 5.4e-125 415.5 14.5 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) PspB PF06667.7 KFP01586.1 - 0.0085 16.0 0.1 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Phage shock protein B DUF1049 PF06305.6 KFP01586.1 - 0.017 14.5 2.5 0.067 12.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) FA_desaturase PF00487.19 KFP01586.1 - 2.9 7.2 9.7 0.029 13.8 0.8 2.0 2 1 0 2 2 2 0 Fatty acid desaturase GEMIN8 PF15348.1 KFP01587.1 - 2.5e-78 262.9 18.0 2.9e-78 262.7 12.5 1.0 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Neur_chan_LBD PF02931.18 KFP01588.1 - 4.8e-55 186.0 0.0 6.1e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP01588.1 - 1.1e-45 156.4 4.3 2.3e-38 132.4 1.1 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RDD PF06271.7 KFP01588.1 - 0.36 10.7 3.9 0.14 12.0 0.5 1.8 2 0 0 2 2 2 0 RDD family CRAL_TRIO PF00650.15 KFP01590.1 - 5.9e-28 97.3 0.5 9.7e-28 96.6 0.3 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Motile_Sperm PF00635.21 KFP01590.1 - 1.9e-21 75.7 0.0 4.8e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain CRAL_TRIO_2 PF13716.1 KFP01590.1 - 8.9e-06 25.6 0.1 1.6e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF972 PF06156.8 KFP01590.1 - 1.1 9.6 5.8 0.28 11.5 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ank PF00023.25 KFP01592.1 - 2.6e-41 137.4 10.4 3.3e-06 26.6 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFP01592.1 - 3.4e-39 133.0 3.7 4.4e-20 71.8 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP01592.1 - 3.7e-32 110.1 1.2 5.2e-08 33.1 0.0 4.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01592.1 - 7.4e-29 96.9 5.8 0.00084 19.3 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFP01592.1 - 8.2e-24 83.0 7.5 5.1e-07 29.7 0.2 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFP01592.1 - 1.3e-08 34.5 4.1 2.4e-08 33.6 2.9 1.5 1 0 0 1 1 1 1 SOCS box Bactofilin PF04519.8 KFP01592.1 - 0.15 12.1 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Polymer-forming cytoskeletal Ank_2 PF12796.2 KFP01593.1 - 5.9e-45 151.5 4.2 2.3e-19 69.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01593.1 - 2.8e-43 143.6 7.6 4.7e-07 29.2 0.2 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFP01593.1 - 3.2e-32 110.3 1.8 5.8e-10 39.4 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01593.1 - 2e-27 92.5 4.6 0.00048 20.1 0.0 6.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KFP01593.1 - 3.7e-26 90.5 9.1 2e-05 24.6 0.2 6.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFP01593.1 - 1.5e-12 47.1 3.8 2.8e-12 46.2 2.6 1.5 1 0 0 1 1 1 1 SOCS box DUF1843 PF08898.5 KFP01593.1 - 0.083 12.9 0.2 4.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Nucleotid_trans PF03407.11 KFP01593.1 - 0.16 11.7 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase DUF1191 PF06697.7 KFP01595.1 - 5.1e-05 22.2 0.0 6.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF4381 PF14316.1 KFP01595.1 - 0.0056 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) YajC PF02699.10 KFP01595.1 - 0.016 14.8 0.2 0.098 12.3 0.0 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit DUF3816 PF12822.2 KFP01595.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) CcmH PF03918.9 KFP01595.1 - 0.034 13.1 0.0 0.082 11.8 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein LRR19-TM PF15176.1 KFP01595.1 - 0.062 12.9 0.1 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain IncA PF04156.9 KFP01595.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF1628 PF07790.6 KFP01595.1 - 0.1 13.3 0.1 0.53 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) DUF2500 PF10694.4 KFP01595.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) EphA2_TM PF14575.1 KFP01595.1 - 0.11 12.9 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 KFP01595.1 - 0.13 12.4 0.5 0.3 11.2 0.4 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family zf-CCCH PF00642.19 KFP01596.1 - 1.9e-12 46.5 12.6 6.4e-07 28.9 2.6 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KFP01596.1 - 3.2e-06 26.8 0.4 9.8e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP01596.1 - 0.00022 20.8 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFP01596.1 - 0.00074 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KFP01596.1 - 0.021 14.7 0.1 0.14 12.1 0.0 2.4 2 1 1 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3430 PF11912.3 KFP01596.1 - 0.092 12.5 0.6 0.14 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Clat_adaptor_s PF01217.15 KFP01598.1 - 1.8e-60 202.7 2.2 2.1e-60 202.5 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 7tm_1 PF00001.16 KFP01599.1 - 3.6e-54 183.6 13.4 5.6e-54 182.9 9.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP01599.1 - 1.2e-09 37.6 10.3 2.1e-09 36.9 7.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFP01599.1 - 1.7e-09 37.1 13.4 1.7e-09 37.1 9.3 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF962 PF06127.6 KFP01599.1 - 0.12 12.2 2.2 7.9 6.4 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) CTP_synth_N PF06418.9 KFP01600.1 - 9.3e-119 395.5 0.1 1.3e-118 395.1 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KFP01600.1 - 1.9e-54 184.0 0.0 3e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFP01600.1 - 1.1e-10 41.3 0.0 2.8e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KFP01600.1 - 0.00068 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain VWD PF00094.20 KFP01601.1 - 1.5e-25 90.2 0.0 1.6e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.6 KFP01601.1 - 1e-21 76.9 0.5 1e-21 76.9 0.4 2.8 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 KFP01601.1 - 3e-21 75.2 34.1 5.6e-12 45.5 8.8 4.8 5 0 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain TILa PF12714.2 KFP01601.1 - 5.1e-09 35.7 6.6 5.1e-09 35.7 4.6 4.3 4 1 0 4 4 4 1 TILa domain TILa PF12714.2 KFP01602.1 - 6.4e-14 51.4 97.3 0.024 14.3 1.0 11.1 7 4 4 11 11 11 11 TILa domain MACPF PF01823.14 KFP01603.1 - 5e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 MAC/Perforin domain BTB PF00651.26 KFP01604.1 - 7.8e-27 93.4 0.3 1.4e-26 92.6 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP01604.1 - 1.2e-15 56.8 16.3 6.1e-07 29.4 3.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP01604.1 - 8.7e-12 44.6 20.7 2.8e-05 24.1 1.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP01604.1 - 1.9e-10 40.3 16.9 8.9e-05 22.5 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3342 PF11822.3 KFP01604.1 - 5.8e-05 22.3 0.2 5.8e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) zf-C2H2_2 PF12756.2 KFP01604.1 - 0.00029 20.9 6.5 0.042 13.9 0.0 3.4 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFP01604.1 - 0.00029 20.8 10.3 0.11 12.7 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP01604.1 - 0.0086 16.2 18.5 0.056 13.6 0.5 4.3 5 0 0 5 5 4 2 Zinc-finger of C2H2 type BTB_2 PF02214.17 KFP01604.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain zf-DNA_Pol PF08996.5 KFP01604.1 - 0.41 9.9 3.1 1.9 7.8 0.3 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Elf1 PF05129.8 KFP01604.1 - 0.43 10.2 3.0 0.35 10.5 0.5 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 KFP01604.1 - 0.81 9.5 16.6 2.1 8.1 0.2 3.6 2 1 0 2 2 2 0 BED zinc finger zf-trcl PF13451.1 KFP01604.1 - 1.2 8.7 4.8 1.9 8.1 1.1 2.6 2 1 1 3 3 3 0 Probable zinc-binding domain C1_1 PF00130.17 KFP01604.1 - 2.2 8.0 7.1 6.4 6.5 0.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3694 PF12473.3 KFP01605.1 - 6.1e-38 129.6 0.1 8e-38 129.2 0.1 1.2 1 0 0 1 1 1 1 Kinesin protein PID PF00640.18 KFP01605.1 - 0.015 15.2 0.7 0.028 14.3 0.5 1.5 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) 7tm_1 PF00001.16 KFP01606.1 - 1.4e-44 152.1 19.0 1.4e-44 152.1 13.1 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP01606.1 - 0.89 8.6 27.6 0.034 13.2 14.6 1.9 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx CS PF04969.11 KFP01608.1 - 1.7e-14 54.0 0.7 3.3e-14 53.1 0.2 1.7 2 0 0 2 2 2 1 CS domain SGS PF05002.10 KFP01608.1 - 5.4e-14 51.7 3.9 1.2e-13 50.5 2.7 1.6 1 0 0 1 1 1 1 SGS domain Siah-Interact_N PF09032.6 KFP01608.1 - 6.9e-10 38.8 1.3 6.9e-10 38.8 0.9 2.7 2 1 0 2 2 2 1 Siah interacting protein, N terminal Ribosomal_S14 PF00253.16 KFP01609.1 - 2.3e-17 62.0 0.4 2.3e-17 62.0 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e fn3 PF00041.16 KFP01610.1 - 3.7e-119 389.1 25.4 1.7e-15 56.8 0.0 9.3 9 0 0 9 9 9 9 Fibronectin type III domain Fibrinogen_C PF00147.13 KFP01610.1 - 8.7e-77 257.8 8.5 1.7e-76 256.9 5.9 1.5 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Interfer-bind PF09294.5 KFP01610.1 - 4.5e-13 49.1 0.0 0.0095 15.9 0.0 7.5 8 0 0 8 8 8 2 Interferon-alpha/beta receptor, fibronectin type III EGF_2 PF07974.8 KFP01610.1 - 3.3e-10 39.9 99.7 0.00031 20.8 8.5 6.0 6 1 0 6 6 6 4 EGF-like domain hEGF PF12661.2 KFP01610.1 - 5.9e-06 26.0 39.2 0.1 12.7 0.5 6.4 6 0 0 6 6 6 4 Human growth factor-like EGF DUF2369 PF10179.4 KFP01610.1 - 0.063 12.3 4.8 38 3.2 0.0 5.8 7 0 0 7 7 7 0 Uncharacterised conserved protein (DUF2369) Uroplakin_II PF07353.7 KFP01610.1 - 0.11 11.8 1.8 14 4.9 0.1 4.1 4 0 0 4 4 4 0 Uroplakin II EGF PF00008.22 KFP01610.1 - 1.3 9.0 73.3 0.34 10.9 7.3 5.7 5 0 0 5 5 5 0 EGF-like domain WD40 PF00400.27 KFP01611.1 - 1.9e-30 103.5 7.2 2.7e-06 27.0 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-C3HC4 PF00097.20 KFP01611.1 - 4.8e-10 38.9 12.1 1.4e-09 37.4 8.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP01611.1 - 6.2e-10 38.9 11.3 2.2e-09 37.2 7.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP01611.1 - 2.9e-09 36.4 7.4 8.8e-09 34.9 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP01611.1 - 5e-09 35.8 9.3 5e-09 35.8 6.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFP01611.1 - 1.1e-07 31.4 10.6 1.1e-07 31.4 7.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP01611.1 - 4.3e-07 29.7 11.0 1.5e-06 28.0 7.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFP01611.1 - 5.1e-05 22.9 7.7 0.00016 21.3 5.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFP01611.1 - 0.0043 16.5 10.0 0.018 14.6 7.1 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFP01611.1 - 0.22 11.6 14.3 0.03 14.4 5.6 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger AAA_23 PF13476.1 KFP01611.1 - 0.99 9.6 6.0 2.6 8.3 4.2 1.7 1 0 0 1 1 1 0 AAA domain zf-Nse PF11789.3 KFP01611.1 - 4.1 7.0 11.6 0.44 10.1 4.4 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Laminin_G_3 PF13385.1 KFP01612.1 - 6.3e-18 65.4 0.4 1.2e-17 64.5 0.3 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_M43 PF05572.8 KFP01612.1 - 2.7e-13 49.8 0.2 7.4e-13 48.3 0.2 1.8 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Sushi PF00084.15 KFP01612.1 - 1.2e-08 35.2 60.6 1.6e-05 25.1 0.9 9.0 9 0 0 9 9 9 4 Sushi domain (SCR repeat) Notch PF00066.12 KFP01612.1 - 3.7e-07 30.2 9.7 3.7e-07 30.2 6.7 5.4 4 2 1 5 5 4 2 LNR domain Laminin_G_2 PF02210.19 KFP01612.1 - 0.00074 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Reprolysin_2 PF13574.1 KFP01612.1 - 0.019 15.0 0.2 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KFP01612.1 - 0.034 13.0 0.6 0.065 12.0 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.3 KFP01612.1 - 0.064 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.1 KFP01612.1 - 0.076 13.5 0.6 0.15 12.6 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP01612.1 - 0.091 12.2 2.5 0.31 10.5 1.7 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Selenoprotein_S PF06936.6 KFP01612.1 - 0.32 10.5 0.1 0.53 9.7 0.0 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) FXa_inhibition PF14670.1 KFP01613.1 - 7.7e-13 48.3 33.6 2.8e-09 36.9 2.3 4.0 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site Tme5_EGF_like PF09064.5 KFP01613.1 - 0.0023 17.5 6.9 0.0041 16.6 2.5 3.0 2 0 0 2 2 2 1 Thrombomodulin like fifth domain, EGF-like MACPF PF01823.14 KFP01613.1 - 0.0049 16.5 0.3 0.022 14.4 0.1 2.0 2 0 0 2 2 2 1 MAC/Perforin domain UPF0560 PF10577.4 KFP01613.1 - 0.033 12.4 0.0 0.049 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 EGF_3 PF12947.2 KFP01613.1 - 2.9 7.9 12.4 0.6 10.1 4.5 3.1 2 0 0 2 2 2 0 EGF domain MACPF PF01823.14 KFP01614.1 - 4.3e-06 26.5 0.0 8.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 MAC/Perforin domain Sec16_C PF12931.2 KFP01615.1 - 4.4e-34 118.5 0.0 6.8e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KFP01615.1 - 2.2e-20 72.7 0.0 3.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region RasGEF PF00617.14 KFP01616.1 - 1.6e-57 194.3 0.2 3.9e-57 193.0 0.2 1.7 1 1 0 1 1 1 1 RasGEF domain PH PF00169.24 KFP01616.1 - 5.7e-05 23.2 0.1 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP01616.1 - 0.029 14.6 0.1 0.057 13.6 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Fibrinogen_C PF00147.13 KFP01617.1 - 2.3e-74 249.9 10.0 3.1e-74 249.5 7.0 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain zf-C4H2 PF10146.4 KFP01617.1 - 0.025 14.5 0.3 0.041 13.8 0.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Fer4_NifH PF00142.13 KFP01617.1 - 0.11 11.6 1.1 0.17 11.0 0.7 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2115 PF09888.4 KFP01617.1 - 0.17 12.0 5.5 0.26 11.3 3.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Fib_alpha PF08702.5 KFP01617.1 - 9.7 6.3 13.5 44 4.1 8.7 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1193 PF06702.7 KFP01618.1 - 1.5e-90 302.4 0.0 2.1e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAM198 PF15051.1 KFP01618.1 - 0.0016 17.1 0.0 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 FAM198 protein Torsin PF06309.6 KFP01619.1 - 1.9e-46 157.0 1.3 3.5e-46 156.2 0.5 1.8 2 0 0 2 2 2 1 Torsin AAA_22 PF13401.1 KFP01619.1 - 9.6e-06 25.7 0.4 0.00079 19.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KFP01619.1 - 8.6e-05 22.7 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFP01619.1 - 0.0023 18.1 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase PIF1 PF05970.9 KFP01619.1 - 0.0045 15.9 0.1 0.027 13.4 0.1 1.9 1 1 0 1 1 1 1 PIF1-like helicase NACHT PF05729.7 KFP01619.1 - 0.0071 16.0 0.2 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 NACHT domain SEFIR PF08357.6 KFP01619.1 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 1 1 1 2 2 2 0 SEFIR domain APS_kinase PF01583.15 KFP01619.1 - 0.095 12.3 0.0 0.37 10.4 0.0 2.0 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_17 PF13207.1 KFP01619.1 - 0.15 12.9 0.1 0.3 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.12 KFP01620.1 - 7.8e-98 326.6 0.0 1.2e-97 326.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP01620.1 - 1.1e-49 168.9 0.0 3.1e-49 167.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain F_actin_bind PF08919.5 KFP01620.1 - 2e-31 107.9 0.0 4.2e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 F-actin binding SH2 PF00017.19 KFP01620.1 - 2e-24 85.1 0.1 4.7e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFP01620.1 - 2.6e-12 45.9 0.0 4.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP01620.1 - 2e-09 36.9 0.0 3.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP01620.1 - 7.5e-08 31.7 0.0 1.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFP01620.1 - 3.8e-06 26.9 0.8 1.1e-05 25.5 0.6 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_6 PF12913.2 KFP01620.1 - 0.0056 15.8 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain of the SH3b1 type Kinase-like PF14531.1 KFP01620.1 - 0.0063 15.5 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP01620.1 - 0.24 11.0 0.0 1.2 8.8 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family MBOAT PF03062.14 KFP01621.1 - 1.2e-45 156.0 36.7 1.8e-45 155.5 25.4 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ax_dynein_light PF10211.4 KFP01622.1 - 7.9e-09 35.6 9.2 7.9e-09 35.6 6.4 2.6 3 1 0 3 3 3 1 Axonemal dynein light chain Peptidase_S46 PF10459.4 KFP01622.1 - 0.39 9.0 3.3 0.53 8.6 2.3 1.1 1 0 0 1 1 1 0 Peptidase S46 KxDL PF10241.4 KFP01622.1 - 1.6 8.6 5.9 0.8 9.6 0.1 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein Band_7 PF01145.20 KFP01623.1 - 2.2e-27 96.1 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFP01623.1 - 0.0011 18.5 0.3 0.0019 17.7 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GatB_N PF02934.10 KFP01623.1 - 0.036 12.9 0.2 0.045 12.6 0.1 1.1 1 0 0 1 1 1 0 GatB/GatE catalytic domain Synapsin PF02078.11 KFP01623.1 - 0.13 12.4 0.1 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Synapsin, N-terminal domain OST-HTH PF12872.2 KFP01624.1 - 0.00058 19.6 0.0 0.0017 18.1 0.0 1.8 3 0 0 3 3 3 1 OST-HTH/LOTUS domain TUDOR PF00567.19 KFP01625.1 - 1.2e-14 54.2 0.1 2.4e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Tudor domain FAM163 PF15069.1 KFP01626.1 - 7.6e-47 159.4 0.5 8.6e-47 159.3 0.4 1.0 1 0 0 1 1 1 1 FAM163 family DUF4006 PF13179.1 KFP01626.1 - 0.012 15.1 2.7 0.02 14.4 1.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Herpes_LMP2 PF07415.6 KFP01626.1 - 0.04 12.5 0.3 0.04 12.5 0.2 1.8 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein EphA2_TM PF14575.1 KFP01626.1 - 0.1 13.0 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DHDPS PF00701.17 KFP01627.1 - 8.9e-48 162.3 0.0 1e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family QCR10 PF09796.4 KFP01627.1 - 1.3 8.7 4.8 0.76 9.4 0.2 2.6 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) dsrm PF00035.20 KFP01628.1 - 1.5e-22 79.9 0.2 5.8e-11 42.8 0.1 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.26 KFP01628.1 - 5.2e-14 51.8 0.0 1.2e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFP01628.1 - 6.2e-08 32.3 0.0 2.2e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.18 KFP01628.1 - 4.4e-06 26.6 0.0 1.3e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_19 PF13245.1 KFP01628.1 - 0.0027 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KFP01628.1 - 0.0027 17.5 0.0 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFP01628.1 - 0.0044 15.9 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.1 KFP01628.1 - 0.023 14.2 0.1 0.82 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFP01628.1 - 0.027 14.5 0.1 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KFP01628.1 - 0.046 13.5 0.0 0.88 9.3 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KFP01628.1 - 0.069 12.2 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 KFP01628.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Dicer_dimer PF03368.9 KFP01628.1 - 0.1 12.3 0.0 0.41 10.4 0.0 2.0 1 0 0 1 1 1 0 Dicer dimerisation domain OB_NTP_bind PF07717.11 KFP01629.1 - 1.1e-14 54.2 0.0 1.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFP01629.1 - 0.0059 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_13 PF13166.1 KFP01630.1 - 0.0014 17.2 12.5 0.0017 16.9 8.7 1.0 1 0 0 1 1 1 1 AAA domain Laminin_II PF06009.7 KFP01630.1 - 0.0041 16.8 14.5 0.23 11.1 1.0 3.1 1 1 2 3 3 3 2 Laminin Domain II Spore_coat_CotO PF14153.1 KFP01630.1 - 0.015 14.7 3.2 0.025 14.0 2.2 1.4 1 1 0 1 1 1 0 Spore coat protein CotO Spc7 PF08317.6 KFP01630.1 - 0.027 13.1 14.1 0.039 12.6 9.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Occludin_ELL PF07303.8 KFP01630.1 - 0.085 13.5 4.0 0.14 12.9 0.3 2.4 1 1 1 2 2 2 0 Occludin homology domain GET2 PF08690.5 KFP01630.1 - 0.12 11.5 11.4 0.56 9.3 0.2 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 Bestrophin PF01062.16 KFP01630.1 - 0.15 11.0 2.0 0.099 11.5 0.3 1.4 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF848 PF05852.6 KFP01630.1 - 0.19 11.5 9.9 0.029 14.2 3.0 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) WXG100 PF06013.7 KFP01630.1 - 0.21 11.6 21.1 0.16 11.9 5.0 3.8 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Tropomyosin_1 PF12718.2 KFP01630.1 - 0.34 10.7 19.1 0.23 11.3 6.7 2.4 1 1 1 2 2 2 0 Tropomyosin like HsbA PF12296.3 KFP01630.1 - 0.41 10.4 9.4 2.9 7.7 2.4 2.5 1 1 1 2 2 2 0 Hydrophobic surface binding protein A IncA PF04156.9 KFP01630.1 - 0.57 9.7 11.0 18 4.8 7.7 2.1 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 KFP01630.1 - 0.95 9.5 20.1 1.5 8.8 1.8 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.1 KFP01630.1 - 0.98 9.4 12.0 9.7 6.2 5.5 2.6 1 1 1 2 2 2 0 Up-regulated During Septation DUF1664 PF07889.7 KFP01630.1 - 1.2 8.9 11.0 0.92 9.3 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KFP01630.1 - 1.4 9.0 10.1 4 7.5 2.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YlqD PF11068.3 KFP01630.1 - 1.5 8.8 12.2 0.67 9.9 4.1 2.3 1 1 1 2 2 2 0 YlqD protein ATP-synt_D PF01813.12 KFP01630.1 - 1.5 8.3 10.3 0.13 11.8 3.5 1.9 2 1 0 2 2 2 0 ATP synthase subunit D Mnd1 PF03962.10 KFP01630.1 - 1.5 8.4 14.1 5.4 6.6 4.8 2.6 1 1 1 3 3 3 0 Mnd1 family DUF2203 PF09969.4 KFP01630.1 - 1.9 8.6 8.5 1.3 9.2 0.3 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Reo_sigmaC PF04582.7 KFP01630.1 - 2.1 7.4 6.6 1.9 7.6 2.0 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FUSC PF04632.7 KFP01630.1 - 2.4 6.4 5.0 3.1 6.1 3.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin-6_N PF09177.6 KFP01630.1 - 2.6 8.5 11.0 13 6.3 3.8 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Prominin PF05478.6 KFP01630.1 - 2.6 5.4 8.2 0.75 7.2 2.2 1.9 1 1 1 2 2 2 0 Prominin V_ATPase_I PF01496.14 KFP01630.1 - 5.1 4.8 8.1 0.96 7.2 0.7 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Rho_Binding PF08912.6 KFP01630.1 - 5.8 7.3 10.3 9.7 6.5 0.8 3.0 1 1 2 3 3 3 0 Rho Binding DUF972 PF06156.8 KFP01630.1 - 6.3 7.1 10.8 3.1 8.1 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HisKA_3 PF07730.8 KFP01630.1 - 7 7.0 14.5 6.6 7.1 2.1 4.3 1 1 3 4 4 4 0 Histidine kinase AATF-Che1 PF13339.1 KFP01630.1 - 9.3 6.4 10.6 1.4 9.1 2.2 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Laminin_EGF PF00053.19 KFP01631.1 - 3.2e-31 106.9 104.9 2.6e-10 40.0 8.4 7.8 7 0 0 7 7 7 6 Laminin EGF-like (Domains III and V) Laminin_B PF00052.13 KFP01631.1 - 9.8e-24 83.5 0.0 3.3e-23 81.7 0.0 2.0 1 0 0 1 1 1 1 Laminin B (Domain IV) Nup54 PF13874.1 KFP01631.1 - 7.9 6.1 35.9 0.47 10.1 2.9 4.8 3 1 0 4 4 4 0 Nucleoporin complex subunit 54 CTP_transf_2 PF01467.21 KFP01632.1 - 7.4e-23 81.3 0.0 1.4e-22 80.3 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase SH3_1 PF00018.23 KFP01633.1 - 2.6e-28 97.1 0.0 4.2e-16 58.0 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFP01633.1 - 1.4e-24 85.3 0.3 1.4e-13 50.2 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain TPR_11 PF13414.1 KFP01633.1 - 6e-20 70.6 8.6 2.7e-10 39.7 1.6 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFP01633.1 - 2e-18 65.1 3.0 7.7e-05 22.1 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat SH3_2 PF07653.12 KFP01633.1 - 9.4e-18 63.4 0.0 3.1e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain TPR_2 PF07719.12 KFP01633.1 - 1.6e-16 58.7 3.5 0.0017 18.1 0.2 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFP01633.1 - 3.5e-13 49.2 0.5 9.1e-07 28.7 0.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat PB1 PF00564.19 KFP01633.1 - 2.7e-09 36.5 0.1 5.6e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.1 KFP01633.1 - 1.2e-08 34.1 0.5 0.03 14.0 0.1 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFP01633.1 - 3.2e-07 29.6 0.5 0.0047 16.6 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFP01633.1 - 0.00017 21.8 0.9 14 6.4 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFP01633.1 - 0.00019 21.7 0.8 5.9 7.8 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFP01633.1 - 0.00028 20.8 0.0 0.98 9.7 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFP01633.1 - 0.00067 19.5 0.2 0.93 9.5 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP01633.1 - 0.0017 18.1 1.8 1.5 8.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP01633.1 - 0.0025 18.4 0.2 0.78 10.4 0.0 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP01633.1 - 0.1 12.9 3.4 4.4 7.7 0.8 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat P16-Arc PF04699.9 KFP01634.1 - 2.6e-40 137.9 0.1 2.8e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 KFP01634.1 - 0.0098 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family RasGEF PF00617.14 KFP01635.1 - 1.5e-60 204.1 1.7 1.5e-60 204.1 1.2 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KFP01635.1 - 2.8e-18 65.9 1.8 5.4e-18 65.0 0.1 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif RA PF00788.18 KFP01635.1 - 4.9e-13 49.3 0.1 1.2e-11 44.8 0.0 2.9 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Condensin2nSMC PF12422.3 KFP01635.1 - 0.11 12.2 1.6 9 6.0 0.8 2.4 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Glyco_transf_25 PF01755.12 KFP01636.1 - 4.5e-39 134.1 0.0 6.3e-38 130.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.1 KFP01636.1 - 4.8e-16 58.8 1.4 1.7e-15 57.0 0.3 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Anp1 PF03452.9 KFP01636.1 - 6.6e-05 22.1 0.0 0.00055 19.1 0.0 2.2 1 1 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KFP01636.1 - 0.00042 20.0 0.0 0.68 9.5 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Chordopox_A30L PF06015.7 KFP01636.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Glyco_tranf_2_3 PF13641.1 KFP01636.1 - 0.06 13.1 0.4 0.42 10.3 0.1 2.3 2 1 0 2 2 2 0 Glycosyltransferase like family 2 Aminotran_4 PF01063.14 KFP01636.1 - 0.068 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class IV Sen15 PF09631.5 KFP01637.1 - 2.2e-23 82.3 0.0 2.8e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein RNA_pol_Rpb5_C PF01191.14 KFP01637.1 - 0.04 13.4 0.1 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DUF4612 PF15389.1 KFP01638.1 - 6.5e-17 62.1 2.5 7e-17 62.0 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4612) Glyco_hydro_47 PF01532.15 KFP01639.1 - 1.3e-144 482.2 0.0 1.7e-144 481.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 KFP01639.1 - 2.1e-15 56.2 0.0 4.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 PA domain ComX PF05952.7 KFP01639.1 - 0.098 12.1 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Bacillus competence pheromone ComX DUF1680 PF07944.7 KFP01639.1 - 0.15 10.2 0.0 0.28 9.3 0.0 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Pox_F11 PF04943.7 KFP01640.1 - 0.051 12.4 1.1 0.12 11.1 0.8 1.6 1 1 1 2 2 2 0 Poxvirus F11 protein ChuX_HutX PF06228.8 KFP01640.1 - 0.081 12.3 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Phasin PF05597.6 KFP01640.1 - 0.083 12.6 0.0 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Invas_SpaK PF03519.9 KFP01640.1 - 0.2 11.4 1.8 0.5 10.2 0.2 2.2 2 1 1 3 3 3 0 Invasion protein B family zf-C3HC4 PF00097.20 KFP01641.1 - 4.7e-10 38.9 10.4 8.4e-10 38.1 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP01641.1 - 3.9e-09 36.1 8.2 6.5e-09 35.4 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP01641.1 - 7.4e-08 32.2 9.3 1.2e-07 31.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP01641.1 - 1.1e-06 28.2 8.3 1.6e-06 27.6 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP01641.1 - 6.9e-06 25.6 8.7 1.2e-05 24.9 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP01641.1 - 3e-05 23.7 8.3 6e-05 22.8 5.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KFP01641.1 - 0.00012 21.5 5.9 0.0002 20.7 4.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KFP01641.1 - 0.00032 20.2 7.3 0.00064 19.2 5.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KFP01641.1 - 0.006 16.3 4.1 0.011 15.5 2.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 KFP01641.1 - 0.018 14.5 7.3 0.031 13.7 5.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-UDP PF14569.1 KFP01641.1 - 0.029 14.0 0.9 0.092 12.5 0.6 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.1 KFP01641.1 - 0.056 13.1 7.1 0.15 11.7 4.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 KFP01641.1 - 0.1 12.7 5.7 0.29 11.2 3.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFP01641.1 - 0.18 11.6 2.5 0.35 10.7 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CDC73 PF05179.9 KFP01641.1 - 0.31 10.3 1.9 0.49 9.7 1.3 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family zf-C4_Topoisom PF01396.14 KFP01641.1 - 0.73 9.3 3.8 0.21 11.0 0.5 1.7 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger TRM PF02005.11 KFP01642.1 - 2.4e-69 234.1 4.7 2.4e-58 197.8 0.8 2.7 2 1 1 3 3 3 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 KFP01642.1 - 4.3e-05 23.1 0.1 0.00021 20.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFP01642.1 - 0.00026 20.6 0.1 0.00063 19.3 0.1 1.6 1 1 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 KFP01642.1 - 0.067 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KFP01642.1 - 0.1 13.2 0.0 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PIN_4 PF13638.1 KFP01644.1 - 7.8e-30 103.6 0.1 2e-29 102.3 0.0 1.7 1 0 0 1 1 1 1 PIN domain Mitofilin PF09731.4 KFP01644.1 - 0.067 11.8 0.6 0.099 11.2 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Kelch_1 PF01344.20 KFP01646.1 - 2.6e-82 270.1 8.4 5.3e-15 54.6 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFP01646.1 - 8.6e-54 177.6 4.5 2.2e-11 43.4 0.0 6.4 1 1 5 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFP01646.1 - 9.1e-42 140.3 8.4 1.6e-08 34.4 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP01646.1 - 9.2e-39 129.7 1.6 8.1e-05 22.2 0.1 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFP01646.1 - 2.5e-34 116.8 5.4 5e-07 29.3 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFP01646.1 - 1.3e-26 92.7 0.5 2e-26 92.1 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 KFP01646.1 - 1.1e-15 57.1 6.4 0.0017 18.2 0.0 6.3 6 0 0 6 6 6 4 Kelch motif BACK PF07707.10 KFP01646.1 - 1.5e-10 40.8 0.1 7.5e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch VLPT PF07122.6 KFP01646.1 - 0.0041 16.7 0.7 0.17 11.6 0.9 2.6 2 0 0 2 2 2 1 Variable length PCR target protein (VLPT) DUF3141 PF11339.3 KFP01646.1 - 0.094 11.0 0.4 8.4 4.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) Rax2 PF12768.2 KFP01646.1 - 0.14 11.3 0.3 0.75 8.9 0.0 2.2 2 0 0 2 2 2 0 Cortical protein marker for cell polarity PQQ_3 PF13570.1 KFP01646.1 - 1.8 8.9 7.1 4.2 7.7 0.0 4.2 5 0 0 5 5 4 0 PQQ-like domain I-set PF07679.11 KFP01647.1 - 0 2164.3 0.0 4.9e-21 74.3 0.1 42.1 42 1 0 42 42 41 41 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP01647.1 - 0 1399.5 41.4 2.6e-14 53.1 0.0 42.2 43 0 0 43 43 41 41 Immunoglobulin domain Ig_3 PF13927.1 KFP01647.1 - 1.3e-298 963.8 96.9 2.1e-10 40.9 0.1 43.0 42 1 0 42 42 41 40 Immunoglobulin domain ig PF00047.20 KFP01647.1 - 4.4e-293 946.0 0.0 1.7e-08 34.4 0.0 41.3 40 0 0 40 40 40 40 Immunoglobulin domain V-set PF07686.12 KFP01647.1 - 1.4e-174 569.5 7.3 5.9e-07 29.3 0.0 47.4 36 13 4 41 41 41 34 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP01647.1 - 4.2e-115 375.9 50.2 0.00014 21.6 0.0 39.4 40 0 0 40 40 40 27 CD80-like C2-set immunoglobulin domain EGF_CA PF07645.10 KFP01647.1 - 3e-64 212.7 119.3 6.9e-13 48.3 4.3 10.4 9 0 0 9 9 9 8 Calcium-binding EGF domain G2F PF07474.7 KFP01647.1 - 8.3e-61 204.7 0.0 1.8e-60 203.6 0.0 1.6 1 0 0 1 1 1 1 G2F domain TSP_1 PF00090.14 KFP01647.1 - 4e-54 180.5 138.0 5.3e-13 48.8 5.9 8.9 9 0 0 9 9 6 6 Thrombospondin type 1 domain cEGF PF12662.2 KFP01647.1 - 8.2e-48 159.6 71.3 4.5e-11 42.1 0.9 11.0 10 0 0 10 10 10 8 Complement Clr-like EGF-like Receptor_2B4 PF11465.3 KFP01647.1 - 5.8e-22 77.6 0.9 14 5.6 0.0 23.5 31 0 0 31 31 30 0 Natural killer cell receptor 2B4 V-set_CD47 PF08204.6 KFP01647.1 - 1.4e-20 73.3 0.8 19 5.0 0.0 21.9 28 1 1 29 29 26 0 CD47 immunoglobulin-like domain FXa_inhibition PF14670.1 KFP01647.1 - 5.2e-12 45.6 42.6 1.2e-07 31.6 6.3 11.5 13 0 0 13 13 9 6 Coagulation Factor Xa inhibitory site A2M PF00207.17 KFP01647.1 - 4.5e-06 26.1 1.6 2.8 7.5 0.0 7.5 9 0 0 9 9 8 1 Alpha-2-macroglobulin family EGF_3 PF12947.2 KFP01647.1 - 0.00021 21.1 7.9 0.00021 21.1 5.5 9.6 9 0 0 9 9 8 5 EGF domain EGF PF00008.22 KFP01647.1 - 0.012 15.5 107.8 0.0035 17.2 4.1 11.3 7 1 2 9 9 8 0 EGF-like domain Helicase_Sgs1 PF11408.3 KFP01647.1 - 2.8 7.8 0.0 21 5.0 0.0 2.1 2 0 0 2 2 2 0 Sgs1 RecQ helicase DUF2895 PF11444.3 KFP01647.1 - 5 6.2 2.0 2.8e+02 0.5 0.0 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF2895) DUF4007 PF13182.1 KFP01647.1 - 8.3 5.1 0.0 14 4.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) RGS PF00615.14 KFP01648.1 - 3.1e-37 127.2 1.8 4.3e-37 126.8 1.2 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 KFP01649.1 - 3.2e-38 130.4 2.2 4e-38 130.1 1.5 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Gag_p19 PF02228.11 KFP01649.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Major core protein p19 RGS-like PF09128.6 KFP01649.1 - 0.068 12.6 0.1 0.082 12.4 0.1 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain NAD_binding_10 PF13460.1 KFP01650.1 - 9.5e-09 35.5 0.0 1.1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding bZIP_1 PF00170.16 KFP01651.1 - 9.2e-11 41.5 14.7 1.7e-10 40.7 10.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP01651.1 - 9.1e-07 28.6 14.5 9.1e-07 28.6 10.1 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFP01651.1 - 0.004 17.4 10.2 0.004 17.4 7.0 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor OLF PF02191.11 KFP01652.1 - 1.1e-91 306.5 8.9 1.5e-91 306.1 6.2 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 KFP01652.1 - 0.0098 15.6 0.6 0.048 13.4 0.0 2.2 2 0 0 2 2 2 1 Neurogenesis glycoprotein Pkinase_Tyr PF07714.12 KFP01654.1 - 6.5e-86 287.6 0.0 8.4e-86 287.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP01654.1 - 2.8e-45 154.4 0.0 4.7e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain F5_F8_type_C PF00754.20 KFP01654.1 - 0.00011 22.0 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 F5/8 type C domain Shisa PF13908.1 KFP01654.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KFP01654.1 - 0.023 12.9 0.0 0.034 12.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E F5_F8_type_C PF00754.20 KFP01655.1 - 7.7e-16 58.1 0.1 9.1e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain UDPGP PF01704.13 KFP01656.1 - 4.3e-84 282.4 0.0 4.9e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pkinase PF00069.20 KFP01657.1 - 1.5e-25 89.8 0.0 3e-25 88.8 0.0 1.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01657.1 - 2.3e-10 39.9 0.0 4.7e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RRM_5 PF13893.1 KFP01657.1 - 1.9e-08 34.0 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP01657.1 - 5.4e-08 32.3 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP01657.1 - 1.1e-06 28.4 0.0 2.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Kinase-like PF14531.1 KFP01657.1 - 7e-05 21.9 0.0 9.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP01657.1 - 0.0058 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP01657.1 - 0.0081 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFP01657.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF4628 PF15429.1 KFP01658.1 - 7.5e-43 146.9 1.8 8.3e-43 146.7 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4628) PID PF00640.18 KFP01659.1 - 2.6e-27 95.5 0.7 2.6e-27 95.5 0.5 1.7 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) CECR6_TMEM121 PF14997.1 KFP01660.1 - 2.1e-60 203.6 11.5 3.5e-60 202.9 8.0 1.3 1 0 0 1 1 1 1 CECR6/TMEM121 family EIID-AGA PF03613.9 KFP01660.1 - 0.0065 15.4 4.5 0.043 12.7 3.1 2.0 1 1 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component DUF996 PF06195.8 KFP01660.1 - 0.33 10.9 12.7 2 8.3 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) LIM PF00412.17 KFP01661.1 - 1.7e-13 50.4 2.4 1.9e-13 50.2 1.7 1.1 1 0 0 1 1 1 1 LIM domain Metallothio_Pro PF02069.11 KFP01661.1 - 0.0099 15.6 0.7 0.012 15.4 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic metallothionein TNFR_c6 PF00020.13 KFP01661.1 - 0.089 12.8 0.8 0.089 12.8 0.6 1.5 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region LIM PF00412.17 KFP01662.1 - 2.2e-25 88.4 15.2 8.5e-15 54.5 2.9 2.2 2 0 0 2 2 2 2 LIM domain Metallothio_Pro PF02069.11 KFP01662.1 - 0.033 14.0 9.0 0.85 9.4 0.2 2.6 3 0 0 3 3 3 0 Prokaryotic metallothionein zf-CCHC_5 PF14787.1 KFP01662.1 - 0.034 13.6 0.1 0.034 13.6 0.1 3.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger TNFR_c6 PF00020.13 KFP01662.1 - 0.035 14.1 10.1 0.98 9.5 0.6 3.3 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region zf-FPG_IleRS PF06827.9 KFP01662.1 - 0.035 13.7 11.3 2.3 7.9 0.1 3.6 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Pea-VEAacid PF08111.6 KFP01662.1 - 0.068 13.2 2.6 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Pea-VEAacid family E6 PF00518.12 KFP01662.1 - 0.096 13.0 2.7 4.6 7.6 0.3 2.4 2 1 0 2 2 2 0 Early Protein (E6) zf-DNA_Pol PF08996.5 KFP01662.1 - 0.14 11.4 5.0 0.42 9.9 0.2 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF329 PF03884.9 KFP01662.1 - 0.2 11.2 15.7 2.6 7.6 1.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF329) DUF1610 PF07754.6 KFP01662.1 - 1.5 9.0 12.1 1.3 9.2 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 KFP01662.1 - 4.2 6.7 14.8 2.1 7.6 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain BAH PF01426.13 KFP01663.1 - 3.3e-24 84.9 0.4 7e-24 83.8 0.1 1.7 2 0 0 2 2 2 1 BAH domain ELM2 PF01448.19 KFP01663.1 - 2.5e-11 44.0 0.1 1.3e-10 41.6 0.0 2.3 2 0 0 2 2 2 1 ELM2 domain GATA PF00320.22 KFP01663.1 - 1.1e-08 34.2 11.0 2.2e-08 33.3 7.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.26 KFP01663.1 - 8.8e-05 22.4 0.0 0.00022 21.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pacs-1 PF10254.4 KFP01664.1 - 9.8e-199 660.1 2.1 9.8e-199 660.1 1.5 1.6 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein Longin PF13774.1 KFP01665.1 - 6.2e-25 86.5 0.1 7.7e-25 86.2 0.0 1.1 1 0 0 1 1 1 1 Regulated-SNARE-like domain EGF PF00008.22 KFP01666.1 - 3e-113 369.0 218.6 3.3e-09 36.5 4.5 15.3 15 0 0 15 15 15 15 EGF-like domain EGF_CA PF07645.10 KFP01666.1 - 7.1e-50 166.7 214.5 4e-08 33.1 4.3 15.2 11 4 4 15 15 15 15 Calcium-binding EGF domain hEGF PF12661.2 KFP01666.1 - 7.2e-36 119.8 139.2 0.00073 19.4 1.8 16.2 15 0 0 15 15 15 13 Human growth factor-like EGF EGF_2 PF07974.8 KFP01666.1 - 1.9e-21 75.9 247.2 0.0034 17.5 8.5 15.4 15 0 0 15 15 15 13 EGF-like domain EGF_3 PF12947.2 KFP01666.1 - 3.1e-14 52.6 206.5 3.7e-05 23.5 2.7 16.1 14 2 1 15 15 15 11 EGF domain cEGF PF12662.2 KFP01666.1 - 8.9e-12 44.4 165.5 0.0084 15.7 0.4 16.9 15 3 0 15 15 15 11 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFP01666.1 - 6.4e-07 29.3 203.9 0.07 13.2 3.0 15.1 9 4 6 15 15 15 9 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.19 KFP01666.1 - 8.2 6.4 199.0 5.3 7.0 4.6 14.5 5 4 9 14 14 14 0 Laminin EGF-like (Domains III and V) Ank PF00023.25 KFP01667.1 - 2.4e-44 146.9 13.7 2e-09 36.7 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 KFP01667.1 - 5.4e-35 119.6 7.6 9.4e-14 51.5 0.2 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP01667.1 - 1.5e-27 94.9 11.5 1.5e-10 40.9 0.7 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01667.1 - 1.1e-24 84.0 3.7 4.9e-05 23.1 0.1 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFP01667.1 - 4.9e-20 71.5 6.0 1.2e-08 35.1 0.3 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Lectin_C PF00059.16 KFP01669.1 - 6.3e-16 58.9 1.8 8e-16 58.5 1.2 1.1 1 0 0 1 1 1 1 Lectin C-type domain HMG_CoA_synt_C PF08540.5 KFP01670.1 - 2.2e-124 414.5 0.0 2.8e-124 414.1 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFP01670.1 - 1.4e-98 327.5 0.2 1.9e-98 327.0 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 KFP01670.1 - 0.0018 17.8 0.3 0.0039 16.8 0.2 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 2-Hacid_dh_C PF02826.14 KFP01671.1 - 5.5e-59 198.2 0.0 9.1e-59 197.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFP01671.1 - 6.9e-37 125.8 0.0 1.3e-36 124.9 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain zf-AD PF07776.10 KFP01672.1 - 0.00083 19.3 1.6 0.00083 19.3 1.1 3.4 3 1 1 4 4 4 1 Zinc-finger associated domain (zf-AD) ATG16 PF08614.6 KFP01672.1 - 0.0089 15.8 15.3 0.0089 15.8 10.6 5.8 1 1 4 5 5 5 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KFP01672.1 - 0.69 9.0 21.3 0.01 15.0 1.8 3.7 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Lzipper-MIP1 PF14389.1 KFP01673.1 - 1.3 9.1 6.6 2.6 8.2 0.3 2.8 1 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4164 PF13747.1 KFP01673.1 - 1.9 8.6 8.8 6.8 6.9 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) UPAR_LY6 PF00021.16 KFP01674.1 - 0.19 12.1 3.0 0.82 10.1 0.6 2.3 2 0 0 2 2 2 0 u-PAR/Ly-6 domain Gag_spuma PF03276.9 KFP01674.1 - 2.7 6.2 8.0 0.065 11.5 1.2 1.4 2 0 0 2 2 2 0 Spumavirus gag protein AMPKBI PF04739.10 KFP01675.1 - 4.5e-30 103.5 0.2 6.7e-30 102.9 0.1 1.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain CBM_48 PF02922.13 KFP01675.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) FMO-like PF00743.14 KFP01676.1 - 5e-250 830.2 0.0 5.6e-250 830.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFP01676.1 - 9.3e-20 71.5 0.0 6.5e-19 68.8 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFP01676.1 - 6.7e-09 35.1 0.2 1.5e-06 27.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFP01676.1 - 5.4e-08 32.9 0.0 3e-05 23.9 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFP01676.1 - 6.5e-06 26.0 1.1 0.048 13.4 0.2 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFP01676.1 - 1.5e-05 24.9 0.1 0.00023 21.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFP01676.1 - 0.001 19.4 1.8 0.021 15.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFP01676.1 - 0.0027 16.2 0.7 0.96 7.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 KFP01676.1 - 0.0053 15.8 0.1 2.2 7.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFP01676.1 - 0.007 15.3 0.5 6.1 5.6 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFP01676.1 - 0.014 14.2 2.0 1.1 7.9 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain DUF4431 PF14485.1 KFP01676.1 - 0.078 12.6 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) NAD_Gly3P_dh_N PF01210.18 KFP01676.1 - 0.67 9.6 2.1 8.3 6.1 0.1 2.8 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.14 KFP01677.1 - 1.5e-254 845.1 0.0 1.7e-254 844.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFP01677.1 - 1.5e-18 67.6 0.0 8.8e-18 65.0 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFP01677.1 - 8.1e-11 42.1 0.0 2.1e-07 31.0 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFP01677.1 - 1.3e-07 30.8 0.1 1.3e-05 24.2 0.0 3.0 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFP01677.1 - 2.1e-07 30.8 1.1 0.0017 18.1 0.1 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFP01677.1 - 6.1e-07 29.3 0.1 2.2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFP01677.1 - 1.7e-06 27.3 0.0 0.031 13.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 KFP01677.1 - 0.00038 20.7 0.6 0.078 13.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFP01677.1 - 0.00093 17.7 0.4 0.079 11.4 0.0 2.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KFP01677.1 - 0.0094 14.8 0.3 1.5 7.6 0.0 2.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFP01677.1 - 0.036 13.1 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFP01677.1 - 0.047 12.5 0.1 3.9 6.1 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.14 KFP01677.1 - 0.051 12.6 0.2 0.88 8.5 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain PAP2 PF01569.16 KFP01678.1 - 8.2e-24 83.7 4.1 1.3e-23 83.0 2.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KFP01678.1 - 0.0014 18.8 1.2 0.0014 18.8 0.8 1.9 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 KFP01678.1 - 0.011 15.2 5.8 0.011 15.2 4.0 1.6 2 1 0 2 2 2 0 PAP2 superfamily RFC1 PF08519.7 KFP01679.1 - 0.0059 16.3 0.1 0.0081 15.9 0.1 1.2 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AhpC-TSA PF00578.16 KFP01680.1 - 1e-13 51.0 0.0 1.5e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KFP01680.1 - 1.4e-12 47.0 0.3 2.3e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KFP01680.1 - 0.00033 20.2 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin SAGA-Tad1 PF12767.2 KFP01681.1 - 6.5e-42 143.9 1.4 3.7e-40 138.1 1.0 2.2 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 KFP01681.1 - 0.032 13.5 0.0 0.075 12.2 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family TNF PF00229.13 KFP01682.1 - 0.054 13.0 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family DUF3262 PF11660.3 KFP01682.1 - 0.07 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) TNF PF00229.13 KFP01683.1 - 4.1e-29 100.7 0.1 5.8e-29 100.2 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family DUF4574 PF15141.1 KFP01683.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) Sad1_UNC PF07738.8 KFP01684.1 - 4.2e-39 133.4 0.0 1e-38 132.1 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MbeD_MobD PF04899.7 KFP01684.1 - 0.082 12.8 4.9 0.24 11.3 3.4 1.8 1 0 0 1 1 1 0 MbeD/MobD like GPI2 PF06432.6 KFP01685.1 - 5.2e-60 203.1 8.4 5.8e-60 203.0 5.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2976 PF11190.3 KFP01685.1 - 0.002 17.5 1.4 0.25 10.9 0.3 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF2976) IncA PF04156.9 KFP01685.1 - 4.5 6.8 7.7 0.095 12.2 0.4 1.8 2 0 0 2 2 2 0 IncA protein Dynamin_M PF01031.15 KFP01686.1 - 3.9e-97 324.6 5.7 3.9e-97 324.6 4.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFP01686.1 - 2.2e-42 144.7 0.0 7.2e-42 143.0 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFP01686.1 - 2.1e-25 88.4 4.5 2.1e-25 88.4 3.1 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain PH PF00169.24 KFP01686.1 - 7e-11 42.2 0.9 1.5e-10 41.1 0.6 1.5 1 0 0 1 1 1 1 PH domain Methyltransf_31 PF13847.1 KFP01687.1 - 3.8e-19 68.7 0.0 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KFP01687.1 - 1e-18 67.9 0.0 6.4e-08 33.1 0.0 3.0 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_11 PF08241.7 KFP01687.1 - 7.2e-18 64.8 0.1 9.3e-12 45.2 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain Spermine_synth PF01564.12 KFP01687.1 - 5.8e-12 45.0 0.0 1.3e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KFP01687.1 - 7.4e-10 38.8 0.0 2.2e-07 30.9 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP01687.1 - 1.9e-09 37.7 0.1 0.00049 20.4 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 KFP01687.1 - 2.1e-06 27.5 0.0 0.0029 17.3 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP01687.1 - 3.1e-06 27.5 0.0 0.012 16.0 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 KFP01687.1 - 9.4e-06 25.0 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Ubie_methyltran PF01209.13 KFP01687.1 - 0.0012 18.0 0.0 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Ham1p_like PF01725.11 KFP01688.1 - 4.3e-34 117.5 0.0 7.3e-16 58.0 0.0 2.0 1 1 0 2 2 2 2 Ham1 family Synaptobrevin PF00957.16 KFP01689.1 - 1.6e-32 110.9 3.0 1.8e-32 110.7 2.1 1.0 1 0 0 1 1 1 1 Synaptobrevin UPF0258 PF06789.7 KFP01689.1 - 0.0018 18.3 0.1 0.0022 18.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) Fzo_mitofusin PF04799.8 KFP01689.1 - 0.034 13.5 1.2 0.04 13.3 0.7 1.3 1 1 0 1 1 1 0 fzo-like conserved region Lectin_N PF03954.9 KFP01689.1 - 0.035 13.5 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2721 PF11026.3 KFP01689.1 - 0.05 13.2 0.2 0.057 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF912 PF06024.7 KFP01689.1 - 0.091 12.8 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2077 PF09850.4 KFP01689.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) RskA PF10099.4 KFP01689.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF1035 PF06281.7 KFP01689.1 - 0.35 10.7 3.1 0.5 10.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) LRR_8 PF13855.1 KFP01690.1 - 5.7e-54 179.7 58.3 1.6e-11 43.8 0.3 6.8 2 2 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFP01690.1 - 6.4e-22 76.7 35.7 0.00075 19.0 0.0 8.7 3 2 8 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP01690.1 - 1.7e-16 57.7 29.1 0.38 10.9 0.0 12.8 13 0 0 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 KFP01690.1 - 0.019 15.0 34.5 3.1 8.3 0.1 11.2 12 0 0 12 12 12 0 Leucine rich repeat LRR_9 PF14580.1 KFP01690.1 - 0.39 10.2 11.4 0.66 9.5 1.1 3.5 2 2 2 4 4 4 0 Leucine-rich repeat LRRNT PF01462.13 KFP01690.1 - 0.85 9.1 17.6 0.025 14.0 2.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Yae1_N PF09811.4 KFP01691.1 - 1.4e-13 50.1 37.9 1.8e+02 1.7 26.3 3.8 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Myotub-related PF06602.9 KFP01693.1 - 9.8e-140 465.3 0.1 1.4e-139 464.7 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KFP01693.1 - 0.0035 16.7 0.0 0.0084 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP01693.1 - 0.0041 16.7 0.1 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP01693.1 - 0.005 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2353 PF09789.4 KFP01693.1 - 0.084 12.1 0.2 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) GRAM PF02893.15 KFP01693.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Shisa PF13908.1 KFP01695.1 - 9.1e-08 32.4 1.6 9.1e-08 32.4 1.1 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator IncA PF04156.9 KFP01695.1 - 0.015 14.9 0.4 0.019 14.5 0.2 1.1 1 0 0 1 1 1 0 IncA protein FAM163 PF15069.1 KFP01695.1 - 0.015 15.8 0.3 0.022 15.3 0.2 1.3 1 0 0 1 1 1 0 FAM163 family E1-E2_ATPase PF00122.15 KFP01696.1 - 5.5e-24 84.4 0.1 9.8e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFP01696.1 - 1.2e-16 61.4 0.6 2.4e-16 60.4 0.4 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP01696.1 - 1.6e-13 50.3 0.0 5e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KFP01696.1 - 2.9e-10 40.9 0.0 1.6e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Colicin_im PF03857.8 KFP01696.1 - 0.0039 16.9 0.2 0.0039 16.9 0.2 2.8 2 0 0 2 2 2 1 Colicin immunity protein Hydrolase_3 PF08282.7 KFP01696.1 - 0.0089 15.6 0.9 0.025 14.1 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 KFP01696.1 - 0.027 13.2 0.2 0.045 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) zf-RING_2 PF13639.1 KFP01697.1 - 1.3e-13 50.5 7.6 2.1e-13 49.8 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP01697.1 - 2.4e-09 37.1 4.4 4.6e-09 36.2 3.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP01697.1 - 2.2e-07 30.4 7.8 3.5e-07 29.7 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP01697.1 - 8.8e-07 28.5 4.5 1.3e-06 27.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP01697.1 - 5.8e-06 26.2 8.0 9.4e-06 25.5 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFP01697.1 - 9.8e-06 25.3 1.7 2e-05 24.3 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KFP01697.1 - 1.2e-05 24.9 6.4 1.9e-05 24.3 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFP01697.1 - 0.012 15.2 4.2 0.019 14.5 2.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KFP01697.1 - 0.13 11.8 2.9 0.25 10.9 2.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.2 KFP01697.1 - 1.3 9.1 5.6 2.8 8.0 3.9 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KFP01697.1 - 7.4 6.6 6.7 14 5.8 4.7 1.4 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.20 KFP01698.1 - 1.6e-52 178.2 0.1 2.2e-52 177.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01698.1 - 3.4e-20 72.2 0.0 5.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP01698.1 - 0.009 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFP01698.1 - 0.017 14.2 0.1 0.064 12.3 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFP01698.1 - 0.027 13.2 0.1 0.7 8.6 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase WH2 PF02205.15 KFP01699.1 - 6.6e-07 28.7 0.1 1.2e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 WH2 motif PAT1 PF09770.4 KFP01699.1 - 3.5 5.7 31.4 3.9 5.5 20.4 1.8 1 1 1 2 2 2 0 Topoisomerase II-associated protein PAT1 7tm_1 PF00001.16 KFP01700.1 - 8.5e-39 133.2 21.1 1e-38 132.9 14.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP01700.1 - 9.9e-06 24.8 11.6 9.9e-06 24.8 8.1 2.0 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP01700.1 - 0.083 11.9 18.8 0.0078 15.3 8.8 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx UCH PF00443.24 KFP01701.1 - 4.4e-70 235.8 3.9 5.1e-70 235.6 2.7 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP01701.1 - 2.6e-37 128.8 1.7 3.1e-37 128.6 1.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4205 PF13898.1 KFP01701.1 - 0.038 12.7 0.2 0.077 11.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4205) Peptidase_C98 PF15499.1 KFP01701.1 - 0.81 8.9 9.7 2.8 7.1 5.0 2.8 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ribosomal_L21e PF01157.13 KFP01702.1 - 5.6e-46 154.4 8.6 5.6e-46 154.4 5.9 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e Jiv90 PF14901.1 KFP01702.1 - 0.091 12.7 0.4 9.5 6.2 0.2 2.2 1 1 1 2 2 2 0 Cleavage inducing molecular chaperone CLP_protease PF00574.18 KFP01702.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Clp protease Ras PF00071.17 KFP01703.1 - 4.7e-31 107.3 0.0 5.8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01703.1 - 3.7e-17 62.9 0.0 6.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFP01703.1 - 5.4e-06 26.3 0.0 7.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KFP01703.1 - 8e-05 21.8 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AlkA_N PF06029.6 KFP01703.1 - 0.019 14.9 0.0 0.06 13.4 0.0 1.9 1 1 0 1 1 1 0 AlkA N-terminal domain GTP_EFTU PF00009.22 KFP01703.1 - 0.049 13.0 0.0 0.083 12.3 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFP01703.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KFP01703.1 - 0.11 12.2 0.1 4.8 6.9 0.0 2.3 1 1 0 2 2 2 0 Dynamin family zf-C2H2 PF00096.21 KFP01704.1 - 5e-29 98.8 63.0 1.1e-05 25.4 1.5 8.2 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP01704.1 - 1.3e-19 69.4 67.2 1.1e-05 25.4 0.9 8.6 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP01704.1 - 4.7e-19 67.2 54.1 0.00047 20.3 0.5 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP01704.1 - 0.0015 18.6 51.3 0.011 15.9 0.9 7.4 8 1 0 8 8 8 4 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KFP01704.1 - 0.02 14.9 25.3 0.19 11.8 3.1 4.8 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Oxidored_molyb PF00174.14 KFP01704.1 - 0.093 12.1 0.4 0.17 11.3 0.3 1.4 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain zf-C2H2_jaz PF12171.3 KFP01704.1 - 0.25 11.5 0.2 0.25 11.5 0.1 7.0 8 1 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP01704.1 - 0.51 10.6 28.1 1.1 9.5 0.1 6.9 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Marek_A PF02124.10 KFP01704.1 - 4.5 6.6 7.5 0.42 10.0 0.5 2.1 2 0 0 2 2 2 0 Marek's disease glycoprotein A IF3_N PF05198.11 KFP01705.1 - 2.3e-18 65.8 0.0 9.6e-18 63.8 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.17 KFP01705.1 - 9.5e-14 50.9 2.0 1.3e-13 50.4 0.6 1.9 2 1 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain Ribosomal_L7Ae PF01248.21 KFP01705.1 - 0.047 13.2 0.0 0.71 9.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3993 PF13158.1 KFP01705.1 - 0.12 12.2 0.5 0.26 11.0 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3993) PDZ PF00595.19 KFP01706.1 - 1.8e-66 220.2 1.8 7.7e-16 58.0 0.0 4.2 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP01706.1 - 1.2e-20 73.1 0.1 1.5e-06 28.0 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.20 KFP01706.1 - 3.5e-08 32.9 6.7 3.5e-08 32.9 4.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP01706.1 - 7e-08 32.1 6.9 7e-08 32.1 4.8 3.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP01706.1 - 2.3e-06 27.4 6.2 2.3e-06 27.4 4.3 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP01706.1 - 8.2e-06 25.4 5.5 8.2e-06 25.4 3.8 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP01706.1 - 3.4e-05 23.4 3.1 3.4e-05 23.4 2.2 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP01706.1 - 7.7e-05 22.4 8.1 7.7e-05 22.4 5.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFP01706.1 - 0.00012 21.7 5.3 0.00042 19.9 3.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KFP01706.1 - 0.0037 17.3 6.0 0.012 15.6 3.0 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger eIF3g PF12353.3 KFP01706.1 - 1.4 8.8 4.2 6.2 6.7 1.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF3489 PF11994.3 KFP01707.1 - 0.053 13.4 0.2 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) AUX_IAA PF02309.11 KFP01707.1 - 0.56 9.9 6.6 0.63 9.7 4.6 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF788 PF05620.6 KFP01707.1 - 6.8 6.5 8.6 0.16 11.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Pkinase PF00069.20 KFP01709.1 - 0.0017 17.5 0.0 0.0045 16.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01710.1 - 8.5e-102 339.6 0.0 1.4e-101 338.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP01710.1 - 2.1e-44 151.6 0.0 6.6e-30 104.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFP01710.1 - 2.1e-26 91.6 0.0 1.4e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP01710.1 - 4.2e-23 81.2 0.0 2.6e-11 43.4 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP01710.1 - 4.5e-18 65.5 0.0 2.7e-08 34.1 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFP01710.1 - 6.5e-11 42.2 0.0 0.00037 20.5 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP01710.1 - 1.4e-10 41.1 0.3 3.3e-05 23.7 0.0 3.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain C1-set PF07654.10 KFP01710.1 - 0.026 14.5 0.1 2.9 7.9 0.0 2.8 2 1 0 2 2 2 0 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFP01710.1 - 0.18 11.7 2.8 0.67 9.8 0.0 2.7 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain APH PF01636.18 KFP01710.1 - 0.21 11.2 0.0 0.56 9.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family UMP1 PF05348.6 KFP01711.1 - 5.6e-30 103.9 0.1 6.1e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MFS_1 PF07690.11 KFP01712.1 - 2.6e-14 52.7 28.2 2.6e-14 52.7 19.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3 PF05106.7 KFP01712.1 - 0.017 15.0 0.8 0.082 12.9 0.5 2.1 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) AA_permease_2 PF13520.1 KFP01715.1 - 1.6e-55 188.4 23.7 1.6e-55 188.4 16.4 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFP01715.1 - 4e-45 154.0 23.1 4e-45 154.0 16.0 2.5 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 KFP01715.1 - 4.1e-25 87.3 9.4 4.1e-25 87.3 6.5 3.9 5 0 0 5 5 5 1 C-terminus of AA_permease Rad60-SLD_2 PF13881.1 KFP01716.1 - 5.9e-32 109.8 0.0 6.8e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFP01716.1 - 0.00032 20.0 0.0 0.00055 19.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Met_gamma_lyase PF06838.6 KFP01716.1 - 0.059 11.6 0.0 0.076 11.3 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase DUF2407 PF10302.4 KFP01716.1 - 0.081 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain AAA PF00004.24 KFP01717.1 - 4.2e-40 137.0 0.0 1e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFP01717.1 - 9.9e-08 31.7 0.1 4.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 KFP01717.1 - 5.7e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFP01717.1 - 1.4e-05 24.2 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KFP01717.1 - 2.5e-05 24.2 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFP01717.1 - 0.00026 20.7 0.4 0.0014 18.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFP01717.1 - 0.00026 19.8 0.0 0.00044 19.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KFP01717.1 - 0.00033 21.4 0.0 0.0014 19.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFP01717.1 - 0.00043 20.4 0.5 0.0044 17.1 0.2 2.7 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KFP01717.1 - 0.0006 19.0 0.2 0.0013 17.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KFP01717.1 - 0.00078 19.4 0.1 0.03 14.3 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KFP01717.1 - 0.0016 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KFP01717.1 - 0.0024 17.7 0.0 0.0069 16.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KFP01717.1 - 0.0036 17.0 0.1 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KFP01717.1 - 0.0043 16.1 0.0 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KFP01717.1 - 0.012 15.0 0.3 0.22 10.8 0.2 2.5 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 KFP01717.1 - 0.012 15.2 0.1 0.067 12.8 0.1 2.1 1 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KFP01717.1 - 0.019 14.9 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFP01717.1 - 0.02 15.1 1.7 0.27 11.5 1.1 2.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KFP01717.1 - 0.028 13.5 0.2 2.1 7.4 0.1 2.4 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 KFP01717.1 - 0.03 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.16 KFP01717.1 - 0.043 13.2 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase RNA_helicase PF00910.17 KFP01717.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 KFP01717.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.1 KFP01717.1 - 0.085 12.6 4.1 0.27 11.0 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat UPF0079 PF02367.12 KFP01717.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KFP01717.1 - 0.15 11.5 0.1 0.37 10.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.14 KFP01718.1 - 4.1e-42 142.2 12.9 1.7e-27 95.4 0.4 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP01718.1 - 7.3e-42 141.6 20.7 1.7e-26 92.3 5.5 2.6 3 0 0 3 3 3 2 HMG-box domain CobT PF06213.7 KFP01718.1 - 0.005 16.0 12.9 0.0074 15.4 8.9 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Lyase_catalyt PF09093.6 KFP01718.1 - 0.0073 15.2 2.4 0.0073 15.2 1.7 1.5 2 0 0 2 2 2 1 Lyase, catalytic HMG_box_5 PF14887.1 KFP01718.1 - 0.031 14.0 17.3 0.33 10.7 2.6 2.5 2 1 0 2 2 2 0 HMG (high mobility group) box 5 BSP_II PF05432.6 KFP01718.1 - 0.53 9.5 20.1 0.85 8.8 13.9 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 KFP01718.1 - 2.3 7.3 13.8 5.1 6.1 9.6 1.7 1 0 0 1 1 1 0 Myc amino-terminal region Nucleo_P87 PF07267.6 KFP01718.1 - 2.4 6.7 15.5 2.9 6.4 10.8 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP_sp32 PF07222.7 KFP01718.1 - 6.7 5.8 16.4 13 4.9 11.4 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PPP4R2 PF09184.6 KFP01718.1 - 7.1 6.0 29.6 0.58 9.6 17.3 1.5 2 0 0 2 2 2 0 PPP4R2 DUF4650 PF15509.1 KFP01719.1 - 2.5e-153 511.7 22.0 2.5e-153 511.7 15.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4650) Peptidase_C98 PF15499.1 KFP01719.1 - 6e-132 439.0 8.6 1.7e-131 437.5 6.0 1.8 1 0 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase MAPEG PF01124.13 KFP01720.1 - 1.8e-08 34.0 0.9 2.1e-08 33.8 0.7 1.2 1 0 0 1 1 1 1 MAPEG family Fringe PF02434.11 KFP01721.1 - 6.5e-66 222.1 0.0 3.6e-58 196.7 0.0 2.6 2 1 1 3 3 3 2 Fringe-like Galactosyl_T PF01762.16 KFP01721.1 - 2.4e-08 33.8 0.0 0.1 12.1 0.0 3.3 2 1 1 3 3 3 3 Galactosyltransferase DUF604 PF04646.7 KFP01721.1 - 0.00028 20.2 0.1 0.0016 17.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Glyco_transf_21 PF13506.1 KFP01721.1 - 0.0029 16.9 0.0 0.32 10.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFP01721.1 - 0.027 14.1 0.0 0.083 12.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 RVT_1 PF00078.22 KFP01722.1 - 1.3e-21 76.9 0.0 2.2e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4 PF00097.20 KFP01723.1 - 2.5e-09 36.6 10.3 2.5e-09 36.6 7.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP01723.1 - 4.2e-08 32.8 9.8 4.2e-08 32.8 6.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP01723.1 - 4.5e-08 32.9 9.5 4.5e-08 32.9 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP01723.1 - 2.6e-05 23.7 9.2 2.6e-05 23.7 6.4 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP01723.1 - 7.9e-05 22.2 11.3 7.9e-05 22.2 7.9 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFP01723.1 - 0.0024 17.9 7.0 0.0024 17.9 4.8 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KFP01723.1 - 0.0035 17.1 9.6 0.0035 17.1 6.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFP01723.1 - 0.0045 16.5 5.9 0.0045 16.5 4.1 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain BAF1_ABF1 PF04684.8 KFP01723.1 - 0.021 13.7 1.5 0.028 13.2 1.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GAGA PF09237.6 KFP01723.1 - 0.023 14.2 0.1 0.073 12.6 0.1 1.8 1 0 0 1 1 1 0 GAGA factor zf-Nse PF11789.3 KFP01723.1 - 0.026 14.0 4.5 0.045 13.2 3.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CDC45 PF02724.9 KFP01723.1 - 0.031 12.3 0.5 0.035 12.1 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-RING_UBOX PF13445.1 KFP01723.1 - 0.034 13.8 4.3 0.1 12.3 2.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger CobT PF06213.7 KFP01723.1 - 0.039 13.0 3.6 0.049 12.7 2.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4512 PF14975.1 KFP01723.1 - 0.055 14.2 0.2 0.12 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) zf-UDP PF14569.1 KFP01723.1 - 0.19 11.5 1.6 0.28 10.9 0.3 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-Apc11 PF12861.2 KFP01723.1 - 0.37 10.6 4.0 1 9.2 2.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 KFP01723.1 - 0.55 10.1 8.8 0.49 10.2 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 KFP01723.1 - 0.6 9.9 7.7 0.23 11.2 3.2 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein MRP-S33 PF08293.6 KFP01724.1 - 2.1e-28 98.1 2.5 2.6e-28 97.8 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Herpes_UL36 PF03586.8 KFP01724.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Pkinase_Tyr PF07714.12 KFP01725.1 - 1.9e-64 217.2 0.0 2.7e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP01725.1 - 1e-60 205.1 0.0 1.4e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RBD PF02196.10 KFP01725.1 - 2.1e-30 104.2 0.0 3.7e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Raf-like Ras-binding domain C1_1 PF00130.17 KFP01725.1 - 7.4e-12 44.8 6.7 1.4e-11 43.8 4.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KFP01725.1 - 2.1e-09 36.7 0.0 3.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-RING-like PF08746.6 KFP01725.1 - 0.00059 19.7 2.6 0.0014 18.5 1.8 1.6 1 0 0 1 1 1 1 RING-like domain C1_3 PF07649.7 KFP01725.1 - 0.071 13.1 5.3 0.15 12.1 3.7 1.6 1 0 0 1 1 1 0 C1-like domain Kdo PF06293.9 KFP01725.1 - 0.082 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP01725.1 - 0.086 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prok-RING_1 PF14446.1 KFP01725.1 - 0.23 11.2 1.8 0.54 10.0 1.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.11 KFP01725.1 - 0.81 9.6 9.2 1.6 8.6 6.3 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger ABC1 PF03109.11 KFP01726.1 - 1.8e-19 69.8 0.0 1.3e-15 57.4 0.0 2.8 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 KFP01726.1 - 0.014 15.1 0.0 0.014 15.1 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DENN PF02141.16 KFP01727.1 - 5.4e-57 192.4 1.2 1.1e-56 191.5 0.8 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFP01727.1 - 1.1e-22 79.8 0.3 2e-22 78.9 0.2 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFP01727.1 - 3e-22 78.4 2.7 6.5e-22 77.3 1.8 1.6 1 0 0 1 1 1 1 dDENN domain SPA PF08616.5 KFP01727.1 - 0.23 11.1 0.2 0.49 10.1 0.1 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Indigoidine_A PF04227.7 KFP01728.1 - 1.1e-128 428.5 2.5 2e-128 427.7 1.4 1.6 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 KFP01728.1 - 1.4e-16 60.5 0.0 2.8e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPP_enzyme_N PF02776.13 KFP01728.1 - 0.033 13.6 0.1 0.39 10.1 0.0 2.7 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain zf-CCCH PF00642.19 KFP01729.1 - 2.2e-13 49.5 33.3 1.1e-05 24.9 0.1 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 KFP01729.1 - 1.6e-07 31.0 5.1 7.6e-07 28.8 3.6 2.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFP01729.1 - 5.8e-07 29.0 7.1 5.8e-07 29.0 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP01729.1 - 1.6e-05 24.5 6.0 1.6e-05 24.5 4.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFP01729.1 - 4.5e-05 23.4 6.0 4.5e-05 23.4 4.2 2.9 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFP01729.1 - 0.00013 21.8 5.9 0.00013 21.8 4.1 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFP01729.1 - 0.00046 19.9 2.6 0.00046 19.9 1.8 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFP01729.1 - 0.0025 17.6 4.0 0.0025 17.6 2.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFP01729.1 - 0.0025 17.5 2.8 0.0057 16.3 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_2 PF14608.1 KFP01729.1 - 0.22 11.5 29.5 0.34 10.9 0.1 5.3 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Ras PF00071.17 KFP01730.1 - 2.1e-56 189.7 0.6 2.4e-56 189.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01730.1 - 2.1e-19 70.1 0.1 3.5e-19 69.4 0.1 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KFP01730.1 - 2.1e-15 56.3 0.2 2.8e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP01730.1 - 3.2e-06 26.7 0.6 1.3e-05 24.7 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP01730.1 - 1.4e-05 24.3 0.1 1.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP01730.1 - 3.1e-05 23.8 0.0 4.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFP01730.1 - 0.00023 20.4 0.1 0.0006 19.0 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFP01730.1 - 0.00043 19.6 0.6 0.06 12.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B PduV-EutP PF10662.4 KFP01730.1 - 0.0031 17.0 0.5 0.072 12.5 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFP01730.1 - 0.014 15.4 0.1 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain ECIST_Cterm PF14784.1 KFP01730.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein Septin PF00735.13 KFP01730.1 - 0.082 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 KFP01730.1 - 0.12 11.0 0.8 12 4.5 0.3 2.8 1 1 1 2 2 2 0 G-protein alpha subunit MFS_1 PF07690.11 KFP01731.1 - 4.9e-41 140.6 26.3 2e-37 128.7 9.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily JmjC PF02373.17 KFP01732.1 - 1.9e-11 44.2 2.1 3e-10 40.3 1.4 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KFP01732.1 - 5.4e-10 39.1 4.8 8.2e-09 35.3 0.1 2.8 2 0 0 2 2 2 2 Cupin-like domain AA_permease_2 PF13520.1 KFP01733.1 - 9.6e-52 175.9 36.5 1.1e-51 175.7 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFP01733.1 - 1.3e-25 89.6 26.7 1.3e-25 89.6 18.5 1.9 2 0 0 2 2 2 2 Amino acid permease PARP PF00644.15 KFP01734.1 - 8.6e-42 142.8 0.0 3.1e-41 141.0 0.0 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain HJURP_C PF12347.3 KFP01734.1 - 0.079 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Aldo_ket_red PF00248.16 KFP01735.1 - 1.2e-47 162.0 0.0 1.4e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bromodomain PF00439.20 KFP01736.1 - 1.1e-21 76.5 0.1 3.3e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 Bromodomain zf-B_box PF00643.19 KFP01736.1 - 4.9e-11 42.3 24.1 5.4e-09 35.7 5.5 4.9 5 0 0 5 5 5 2 B-box zinc finger PHD PF00628.24 KFP01736.1 - 4.8e-08 32.5 11.3 4.8e-08 32.5 7.8 4.5 4 0 0 4 4 4 1 PHD-finger MFS_1 PF07690.11 KFP01737.1 - 2.3e-30 105.5 42.7 1.7e-22 79.6 14.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP01737.1 - 7.7e-23 80.7 34.2 7.4e-20 70.9 6.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter V_ATPase_I PF01496.14 KFP01738.1 - 1.2e-284 946.0 8.8 1.3e-284 945.8 6.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMEM213 PF15192.1 KFP01739.1 - 5.3e-37 125.6 2.3 5.6e-37 125.6 1.6 1.0 1 0 0 1 1 1 1 TMEM213 family DUF3827 PF12877.2 KFP01740.1 - 6.6e-287 953.1 4.2 8.6e-287 952.8 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) SKG6 PF08693.5 KFP01740.1 - 0.01 15.1 3.2 0.022 14.0 2.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 KFP01740.1 - 0.012 15.8 0.9 0.06 13.5 0.5 2.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4448 PF14610.1 KFP01740.1 - 0.058 12.8 0.2 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Pkinase PF00069.20 KFP01741.1 - 3.8e-54 183.5 0.0 7.2e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01741.1 - 1.7e-24 86.2 0.0 2.9e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFP01741.1 - 1.2e-06 27.7 0.0 4.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP01741.1 - 0.0029 17.3 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFP01741.1 - 0.0036 16.1 0.1 0.0054 15.5 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KFP01741.1 - 0.054 12.8 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Chorion_2 PF03964.10 KFP01741.1 - 4 8.0 8.6 0.38 11.3 0.9 2.6 3 0 0 3 3 3 0 Chorion family 2 RVT_1 PF00078.22 KFP01742.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.17 KFP01743.1 - 1.1e-90 304.4 0.7 5e-72 242.8 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 NadA PF02445.11 KFP01743.1 - 0.083 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Quinolinate synthetase A protein PARP PF00644.15 KFP01744.1 - 3.1e-45 154.1 0.9 1.1e-44 152.4 0.6 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain I-set PF07679.11 KFP01745.1 - 8.2e-59 195.4 4.5 3.5e-13 49.2 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin I-set domain fn3 PF00041.16 KFP01745.1 - 9.5e-27 92.9 0.0 7.8e-14 51.5 0.0 3.7 3 1 0 3 3 3 2 Fibronectin type III domain Ig_2 PF13895.1 KFP01745.1 - 1.2e-25 89.4 0.0 0.00096 19.2 0.0 5.5 4 1 1 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFP01745.1 - 6.4e-14 51.8 4.0 0.026 14.3 0.0 5.8 3 2 1 5 5 5 4 Immunoglobulin V-set domain ig PF00047.20 KFP01745.1 - 1.5e-11 44.2 0.0 0.041 14.0 0.0 5.8 5 0 0 5 5 5 3 Immunoglobulin domain Ig_3 PF13927.1 KFP01745.1 - 4.7e-09 36.6 0.0 0.074 13.5 0.0 4.4 5 0 0 5 5 5 2 Immunoglobulin domain C2-set_2 PF08205.7 KFP01745.1 - 0.0002 21.2 0.0 1.9 8.4 0.0 5.1 5 1 0 5 5 5 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFP01745.1 - 0.00081 19.3 1.2 2.5 8.1 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin C1-set domain DUF3016 PF11454.3 KFP01745.1 - 0.0044 16.6 0.0 0.038 13.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3016) SusE PF14292.1 KFP01745.1 - 0.0051 16.6 0.0 0.022 14.5 0.0 2.1 1 0 0 1 1 1 1 SusE outer membrane protein Cullin PF00888.17 KFP01747.1 - 5.2e-14 51.7 0.1 5.7e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Cullin family Exo70 PF03081.10 KFP01747.1 - 0.03 13.1 0.1 0.03 13.1 0.1 1.3 2 0 0 2 2 2 0 Exo70 exocyst complex subunit PCI PF01399.22 KFP01748.1 - 1.7e-19 70.0 0.1 1.7e-19 70.0 0.1 4.2 5 0 0 5 5 5 1 PCI domain Avl9 PF09794.4 KFP01749.1 - 5.8e-11 41.4 0.0 4.4e-07 28.7 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.5 KFP01749.1 - 9.6e-11 41.3 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 KFP01749.1 - 9.9e-09 34.8 0.1 3.4e-08 33.0 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2347) Mtc PF03820.12 KFP01750.1 - 6.3e-33 113.7 0.2 9.7e-33 113.1 0.2 1.2 1 1 0 1 1 1 1 Tricarboxylate carrier SSF PF00474.12 KFP01750.1 - 0.027 13.1 2.5 0.32 9.5 0.2 2.1 2 0 0 2 2 2 0 Sodium:solute symporter family AhpC-TSA PF00578.16 KFP01751.1 - 1e-37 128.6 0.0 1.4e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFP01751.1 - 3.3e-18 65.6 0.0 4.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFP01751.1 - 9.5e-14 50.7 0.0 1.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_8 PF13905.1 KFP01751.1 - 0.053 13.6 0.0 0.097 12.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Pkinase PF00069.20 KFP01752.1 - 1.7e-62 210.9 0.0 2.8e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01752.1 - 7.7e-34 116.9 0.0 1.2e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFP01752.1 - 2.2e-23 82.5 0.1 6.3e-23 81.1 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.1 KFP01752.1 - 0.00015 20.8 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Arteri_nucleo PF01481.11 KFP01752.1 - 0.15 12.1 0.8 4.6 7.3 0.0 3.2 4 0 0 4 4 4 0 Arterivirus nucleocapsid protein RGS PF00615.14 KFP01754.1 - 1.7e-33 115.2 6.0 1.7e-33 115.2 4.1 1.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.6 KFP01754.1 - 0.0025 17.3 0.1 0.0036 16.8 0.1 1.4 1 1 0 1 1 1 1 Regulator of G protein signalling-like domain RRM_1 PF00076.17 KFP01755.1 - 1.8e-59 197.2 0.1 2.1e-21 75.2 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP01755.1 - 6.1e-32 109.4 0.2 2.3e-14 53.1 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP01755.1 - 4.1e-31 106.6 0.4 1.2e-10 41.0 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFP01755.1 - 7.7e-05 22.3 0.5 0.037 13.7 0.0 3.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 KFP01755.1 - 8.4e-05 22.2 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 2 Calcipressin Nup35_RRM PF05172.8 KFP01755.1 - 0.00077 19.1 0.2 0.3 10.8 0.2 3.5 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFP01755.1 - 0.0061 16.3 0.0 4.5 7.1 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif RNA_bind PF08675.6 KFP01755.1 - 0.078 12.9 0.1 4.4 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA binding domain HATPase_c PF02518.21 KFP01755.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BAG PF02179.11 KFP01756.1 - 1.8e-20 72.8 4.3 2.9e-20 72.1 3.0 1.3 1 0 0 1 1 1 1 BAG domain Matrilin_ccoil PF10393.4 KFP01756.1 - 1.2 8.6 3.3 3.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Syja_N PF02383.13 KFP01757.1 - 7.4e-94 314.0 1.1 1.2e-93 313.3 0.8 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KFP01757.1 - 1.9e-29 101.3 0.0 7.5e-29 99.4 0.0 2.1 2 0 0 2 2 2 1 Inositol phosphatase MCM_bind PF09739.4 KFP01758.1 - 5.2e-41 139.0 0.1 8.7e-41 138.3 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 KFP01758.1 - 3e-36 123.7 1.1 6.9e-36 122.5 0.0 2.2 3 0 0 3 3 3 1 Putative alanine racemase WWE PF02825.15 KFP01759.1 - 1.8e-08 33.6 1.2 0.00085 18.6 0.1 2.4 1 1 1 2 2 2 2 WWE domain zf-CCHH PF10283.4 KFP01760.1 - 1.5e-22 79.0 15.2 8.3e-12 44.7 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger (CX5CX6HX5H) motif HUN PF08729.5 KFP01760.1 - 0.00051 19.8 7.0 0.0012 18.6 4.8 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain SsgA PF04686.7 KFP01760.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA F-box-like PF12937.2 KFP01761.1 - 6.9e-11 41.7 0.3 1.5e-10 40.5 0.0 1.7 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 KFP01761.1 - 2.5e-05 23.7 0.0 2.5e-05 23.7 0.0 2.3 3 0 0 3 3 3 1 F-box domain PH PF00169.24 KFP01762.1 - 2.4e-31 107.9 0.0 1.3e-14 54.2 0.0 2.7 3 0 0 3 3 3 2 PH domain DEP PF00610.16 KFP01762.1 - 1.6e-13 50.2 0.0 2.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_9 PF15410.1 KFP01762.1 - 2.4e-10 40.5 0.0 5.1e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 KFP01762.1 - 3.1e-09 36.8 0.0 4.5e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 KFP01762.1 - 1.3e-08 35.0 1.2 0.044 14.0 0.0 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFP01762.1 - 0.00069 19.6 0.1 0.16 12.0 0.0 3.5 2 2 1 3 3 3 1 Pleckstrin homology domain CNRIP1 PF15043.1 KFP01763.1 - 5e-73 243.6 0.0 5.5e-73 243.5 0.0 1.0 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 EF-hand_1 PF00036.27 KFP01764.1 - 1.2e-27 93.0 14.2 1.4e-06 27.1 0.4 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KFP01764.1 - 2.9e-27 94.5 2.9 7.5e-14 51.6 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP01764.1 - 3e-22 76.4 5.8 7.9e-06 25.3 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFP01764.1 - 5.4e-21 72.9 13.6 4.1e-05 22.7 0.2 4.7 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFP01764.1 - 1.9e-20 72.1 7.7 0.00011 21.7 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP01764.1 - 2.3e-08 34.0 0.1 0.00052 20.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFP01764.1 - 1.5e-07 31.0 4.6 0.0062 16.2 0.1 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFP01764.1 - 0.00055 19.7 0.2 0.059 13.2 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.8 KFP01764.1 - 0.042 13.3 0.3 3.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Caleosin related protein OST-HTH PF12872.2 KFP01764.1 - 0.098 12.5 0.1 1.6 8.5 0.1 2.7 3 1 0 3 3 3 0 OST-HTH/LOTUS domain KH_1 PF00013.24 KFP01765.1 - 6.1e-07 28.9 1.2 1.5e-06 27.7 0.8 1.6 1 0 0 1 1 1 1 KH domain WD40 PF00400.27 KFP01766.1 - 6.2e-17 60.7 1.8 4.7e-06 26.2 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFP01766.1 - 0.0079 15.9 0.1 0.15 11.8 0.0 2.5 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 KFP01766.1 - 0.034 13.8 0.1 14 5.3 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Sas10_Utp3 PF04000.10 KFP01767.1 - 1.8e-18 66.4 0.8 2.5e-18 66.0 0.5 1.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Herpes_V23 PF01802.12 KFP01767.1 - 0.016 14.2 0.1 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein SF-assemblin PF06705.6 KFP01767.1 - 0.028 13.5 0.1 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Spc7 PF08317.6 KFP01767.1 - 0.029 13.0 1.2 0.08 11.5 0.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF932 PF06067.6 KFP01767.1 - 0.068 12.4 0.2 0.092 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) ETAA1 PF15350.1 KFP01768.1 - 4.1e-127 425.3 35.7 1.5e-92 311.0 5.8 2.0 1 1 0 2 2 2 2 Ewing's tumour-associated antigen 1 homologue Homeobox_KN PF05920.6 KFP01769.1 - 1.1e-20 73.0 0.6 2e-20 72.1 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFP01769.1 - 2.2e-08 33.6 1.2 3.3e-08 33.0 0.2 1.8 2 0 0 2 2 2 1 Homeobox domain Sprouty PF05210.8 KFP01770.1 - 1.2e-39 134.6 27.4 1.2e-39 134.6 19.0 1.9 2 0 0 2 2 2 1 Sprouty protein (Spry) WH1 PF00568.18 KFP01770.1 - 2.1e-10 40.3 0.0 3.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Actin PF00022.14 KFP01771.1 - 4e-117 390.9 0.0 4.6e-117 390.7 0.0 1.0 1 0 0 1 1 1 1 Actin Ras PF00071.17 KFP01772.1 - 1.4e-67 226.1 1.1 1.6e-67 225.9 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01772.1 - 1.8e-23 83.2 0.0 2.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP01772.1 - 1.6e-17 63.3 0.2 1.9e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP01772.1 - 4.2e-07 29.3 0.1 4.8e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP01772.1 - 2.5e-06 27.0 0.2 5.8e-06 25.8 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP01772.1 - 7.4e-06 25.8 0.1 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFP01772.1 - 1.2e-05 24.6 0.1 1.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 KFP01772.1 - 0.00048 20.3 0.0 0.076 13.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP01772.1 - 0.00061 19.9 0.0 0.00095 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFP01772.1 - 0.0022 17.3 0.0 0.012 14.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KFP01772.1 - 0.0057 15.8 0.1 0.022 13.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KFP01772.1 - 0.017 14.6 0.1 0.86 9.0 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFP01772.1 - 0.033 14.1 0.1 0.092 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KFP01772.1 - 0.046 14.0 0.0 0.064 13.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 KFP01772.1 - 0.047 13.4 0.0 0.071 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KFP01772.1 - 0.05 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 KFP01772.1 - 0.068 12.1 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 KFP01772.1 - 1.1 7.9 5.9 5.8 5.4 0.7 2.8 1 1 1 2 2 2 0 G-protein alpha subunit TOH_N PF12549.3 KFP01774.1 - 0.025 14.1 1.7 0.025 14.1 1.2 2.3 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal SDF PF00375.13 KFP01775.1 - 2.4e-100 336.0 13.9 2.9e-100 335.7 9.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MH2 PF03166.9 KFP01776.1 - 1e-77 260.0 0.0 1.4e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFP01776.1 - 2.3e-45 152.8 4.5 4.3e-45 151.9 3.1 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFP01776.1 - 4.6e-05 23.0 0.0 7.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 BTB PF00651.26 KFP01777.1 - 3.1e-33 114.0 1.2 6.6e-33 113.0 0.3 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP01777.1 - 1.7e-22 78.5 31.6 5.7e-08 32.6 0.7 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFP01777.1 - 2e-11 43.4 29.8 7.2e-05 22.8 0.9 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP01777.1 - 7e-11 41.6 20.8 0.0041 17.3 0.4 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP01777.1 - 0.0012 18.9 20.4 0.025 14.7 1.1 5.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP01777.1 - 0.0033 17.5 17.5 0.081 13.1 0.2 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-RING_3 PF14369.1 KFP01777.1 - 0.006 16.5 1.0 0.95 9.5 0.0 3.7 3 0 0 3 3 3 1 zinc-finger zf-C2H2_6 PF13912.1 KFP01777.1 - 0.055 13.3 10.5 1.5 8.8 0.5 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger GAGA PF09237.6 KFP01777.1 - 0.094 12.3 5.4 0.26 10.8 0.1 3.5 1 1 3 4 4 4 0 GAGA factor zf-Di19 PF05605.7 KFP01777.1 - 0.14 12.3 12.9 1.7 8.8 4.8 3.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFP01777.1 - 0.3 11.2 14.1 3.5 7.8 0.7 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) BSP_II PF05432.6 KFP01777.1 - 0.36 10.0 9.1 0.53 9.5 6.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Endonuclease_7 PF02945.10 KFP01777.1 - 4.3 7.1 10.8 2.6 7.8 2.4 3.0 1 1 1 2 2 2 0 Recombination endonuclease VII dNK PF01712.14 KFP01778.1 - 2.8e-22 79.1 0.1 4.6e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase SKI PF01202.17 KFP01778.1 - 0.00022 21.1 0.5 0.057 13.2 0.1 2.5 3 0 0 3 3 3 2 Shikimate kinase Thymidylate_kin PF02223.12 KFP01778.1 - 0.00039 19.8 0.5 0.001 18.4 0.3 1.9 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.1 KFP01778.1 - 0.0016 19.2 0.0 0.0063 17.3 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFP01778.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KFP01778.1 - 0.0032 17.3 0.0 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_33 PF13671.1 KFP01778.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KFP01778.1 - 0.039 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KFP01778.1 - 0.044 14.0 0.4 5.7 7.2 0.0 2.6 2 1 1 3 3 3 0 AAA domain Hist_deacetyl PF00850.14 KFP01779.1 - 6.7e-93 311.3 0.0 6.7e-93 311.3 0.0 2.6 3 0 0 3 3 3 1 Histone deacetylase domain HDAC4_Gln PF12203.3 KFP01779.1 - 1.4e-35 121.0 46.0 1.4e-35 121.0 31.9 4.0 2 1 1 3 3 3 1 Glutamine rich N terminal domain of histone deacetylase 4 Arb2 PF09757.4 KFP01779.1 - 0.0071 15.8 0.1 0.0071 15.8 0.0 2.1 2 0 0 2 2 2 1 Arb2 domain HLH PF00010.21 KFP01780.1 - 3.1e-17 61.9 0.6 6.1e-17 61.0 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Toxin_trans PF07952.7 KFP01780.1 - 0.0091 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain RNA_pol_I_A49 PF06870.7 KFP01780.1 - 0.039 12.5 0.7 0.053 12.0 0.5 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Ank_2 PF12796.2 KFP01781.1 - 2.9e-48 162.1 0.4 2.5e-21 75.8 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01781.1 - 1.8e-30 103.1 4.5 5.8e-08 32.1 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KFP01781.1 - 3.3e-23 81.1 5.2 4.1e-08 33.2 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01781.1 - 1.9e-21 74.0 3.3 1.5e-05 24.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFP01781.1 - 2.6e-16 59.6 0.2 5.3e-10 39.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFP01781.1 - 4.1e-11 42.5 1.7 7.3e-11 41.7 1.1 1.4 1 0 0 1 1 1 1 SOCS box MIP-T3 PF10243.4 KFP01782.1 - 2.6e-135 451.9 73.4 2.4e-133 445.4 50.9 2.0 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 UCH PF00443.24 KFP01783.1 - 4.4e-47 160.4 2.8 1.6e-41 142.1 0.3 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP01783.1 - 5.5e-26 91.6 2.4 1.9e-25 89.8 0.0 2.3 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase YukD PF08817.5 KFP01783.1 - 0.024 15.1 0.0 1 9.9 0.0 3.3 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD UDPGT PF00201.13 KFP01784.1 - 2.2e-37 128.8 0.1 2.4e-37 128.6 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 KFP01785.1 - 6.7e-37 127.1 0.1 7.4e-37 127.0 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 KFP01786.1 - 2e-44 151.9 0.0 2.2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.13 KFP01787.1 - 3.8e-44 151.1 0.2 4.1e-44 150.9 0.1 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase FOP_dimer PF09398.5 KFP01787.1 - 0.13 12.2 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 FOP N terminal dimerisation domain UDPGT PF00201.13 KFP01788.1 - 6.2e-171 569.3 0.5 3.5e-89 299.6 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFP01788.1 - 6.3e-06 25.9 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Prominin PF05478.6 KFP01788.1 - 0.00031 18.4 0.7 0.00048 17.8 0.5 1.3 1 0 0 1 1 1 1 Prominin Glyco_trans_1_3 PF13528.1 KFP01788.1 - 0.0013 17.9 0.0 0.0042 16.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 1 SH3_2 PF07653.12 KFP01789.1 - 3e-22 77.8 0.1 1.9e-10 40.0 0.1 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.1 KFP01789.1 - 5.8e-13 48.1 0.7 1.1e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFP01789.1 - 9.1e-11 40.9 0.6 4.9e-10 38.6 0.0 2.5 2 1 0 2 2 2 1 SH3 domain ZU5 PF00791.15 KFP01789.1 - 8.2e-07 28.6 0.1 1.8e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 ZU5 domain SH3_3 PF08239.6 KFP01789.1 - 0.16 12.1 3.8 0.57 10.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain Arf PF00025.16 KFP01790.1 - 2.8e-62 209.0 0.0 3.1e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP01790.1 - 1.2e-15 57.2 0.0 1.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP01790.1 - 3.9e-11 42.4 0.0 6e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFP01790.1 - 2.3e-10 40.9 0.0 3.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KFP01790.1 - 7.8e-08 31.4 0.1 2.4e-06 26.5 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFP01790.1 - 4.7e-06 26.1 0.0 2.2e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP01790.1 - 9.8e-06 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP01790.1 - 0.00075 18.7 0.0 0.00093 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.13 KFP01790.1 - 0.053 12.5 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 KFP01790.1 - 0.12 11.7 0.0 0.97 8.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Spp-24 PF07448.6 KFP01792.1 - 8.6e-20 71.1 0.2 1.3e-19 70.5 0.2 1.3 1 0 0 1 1 1 1 Secreted phosphoprotein 24 (Spp-24) Cathelicidins PF00666.12 KFP01792.1 - 2.4e-06 27.5 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Cathelicidin Cystatin PF00031.16 KFP01792.1 - 0.0044 17.1 0.0 0.0067 16.5 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain Ion_trans PF00520.26 KFP01793.1 - 1e-10 41.2 19.5 1e-10 41.2 13.5 3.2 3 1 0 3 3 3 1 Ion transport protein ArfGap PF01412.13 KFP01794.1 - 1.6e-40 137.5 0.0 3.8e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Miro PF08477.8 KFP01794.1 - 7.1e-23 81.3 0.0 1.6e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFP01794.1 - 2.5e-18 65.9 0.0 4.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.2 KFP01794.1 - 2e-15 56.9 0.1 5e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01794.1 - 1.4e-12 46.6 0.2 5.3e-08 32.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat PH PF00169.24 KFP01794.1 - 1.8e-10 40.9 1.6 8.7e-10 38.7 0.1 2.8 2 1 0 2 2 2 1 PH domain Ank_5 PF13857.1 KFP01794.1 - 7.3e-10 38.7 0.7 2.5e-09 37.0 0.4 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP01794.1 - 1e-08 35.4 0.1 9.8e-07 29.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01794.1 - 3.1e-06 26.9 0.0 6.7e-05 22.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat PH_6 PF15406.1 KFP01794.1 - 0.0016 18.4 0.3 0.004 17.1 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFP01794.1 - 0.0076 16.4 2.8 0.53 10.5 0.0 3.0 3 0 0 3 3 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFP01794.1 - 0.057 13.4 0.6 5 7.2 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Chibby PF14645.1 KFP01794.1 - 1.2 9.0 4.7 0.24 11.2 0.6 1.8 2 0 0 2 2 1 0 Chibby family AAA PF00004.24 KFP01795.1 - 6.3e-15 55.5 0.0 1.4e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.22 KFP01795.1 - 1.2e-05 24.5 0.6 2.6e-05 23.4 0.4 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1666 PF07891.7 KFP01795.1 - 0.0027 17.1 1.8 0.0027 17.1 1.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1666) PCI_Csn8 PF10075.4 KFP01796.1 - 4.8e-35 120.4 0.0 5.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KFP01796.1 - 0.0025 17.3 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 KFP01796.1 - 0.0088 16.3 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 PCI domain DUF2051 PF09738.4 KFP01798.1 - 1.7e-90 303.4 64.2 6.8e-54 183.1 16.8 5.1 3 1 1 4 4 4 3 Double stranded RNA binding protein (DUF2051) Fib_alpha PF08702.5 KFP01798.1 - 0.022 14.8 38.4 0.042 13.9 8.1 4.3 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 KFP01798.1 - 0.25 9.7 40.4 0.72 8.2 8.5 2.3 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.7 KFP01798.1 - 0.27 10.9 64.5 0.031 14.0 15.3 4.4 3 2 0 4 4 4 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFP01798.1 - 0.32 10.1 8.1 0.57 9.3 0.2 3.1 2 2 1 4 4 4 0 Reovirus sigma C capsid protein IncA PF04156.9 KFP01798.1 - 1.2 8.7 67.6 0.075 12.6 6.7 5.2 3 2 2 5 5 5 0 IncA protein DUF3584 PF12128.3 KFP01798.1 - 2.9 5.1 48.7 0.0026 15.2 10.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) APG6 PF04111.7 KFP01798.1 - 4.5 6.2 65.5 0.53 9.2 8.1 4.4 3 2 1 4 4 4 0 Autophagy protein Apg6 DUF4279 PF14106.1 KFP01798.1 - 6.6 6.6 7.9 0.88 9.4 0.2 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4279) UQ_con PF00179.21 KFP01800.1 - 7.2e-29 100.0 0.0 8.3e-29 99.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP01800.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-DBF PF07535.7 KFP01801.1 - 1.3e-07 31.1 7.3 3.3e-07 29.8 5.0 1.7 1 0 0 1 1 1 1 DBF zinc finger 7tm_1 PF00001.16 KFP01802.1 - 2e-49 168.0 24.5 2.7e-49 167.6 17.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFP01802.1 - 0.00022 20.4 5.6 0.00022 20.4 3.9 2.2 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw EF1_GNE PF00736.14 KFP01803.1 - 1.2e-35 121.1 0.5 1.9e-35 120.3 0.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFP01803.1 - 7.8e-14 51.5 9.6 3.3e-13 49.5 6.7 2.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Molybdopterin PF00384.17 KFP01804.1 - 3.9e-74 249.9 0.0 4.4e-73 246.4 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 KFP01804.1 - 1e-18 66.2 0.1 2.4e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KFP01804.1 - 2e-17 62.7 0.1 5.3e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 KFP01804.1 - 1.1e-09 37.9 0.4 1.1e-09 37.9 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 KFP01804.1 - 3.3e-08 33.5 0.1 7.1e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) TPP_enzyme_M PF00205.17 KFP01804.1 - 0.11 12.1 1.1 6.6 6.5 0.1 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-C3Hc3H PF13891.1 KFP01805.1 - 4.4e-19 68.3 8.3 4.4e-19 68.3 5.7 1.8 2 0 0 2 2 2 1 Potential DNA-binding domain zf-primase PF09329.6 KFP01805.1 - 0.067 12.8 0.1 0.067 12.8 0.1 2.1 2 0 0 2 2 2 0 Primase zinc finger Phage_Treg PF04761.7 KFP01808.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator MIP-T3 PF10243.4 KFP01809.1 - 0.13 10.7 17.4 0.12 10.7 12.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FLO_LFY PF01698.11 KFP01809.1 - 0.2 10.4 6.8 0.22 10.3 4.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 KFP01809.1 - 0.22 11.3 11.2 0.22 11.3 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 KFP01809.1 - 0.24 11.3 5.9 0.24 11.3 4.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_DNAp_acc PF04929.7 KFP01809.1 - 0.37 9.7 9.0 0.43 9.5 6.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDHD PF02862.12 KFP01809.1 - 2.3 7.9 8.1 2.7 7.7 5.6 1.2 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 KFP01809.1 - 6.3 6.1 14.2 8.4 5.7 9.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.8 KFP01809.1 - 9.3 4.6 8.6 12 4.3 6.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PDZ PF00595.19 KFP01810.1 - 5.9e-22 77.6 0.3 4.7e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP01810.1 - 4.5e-10 39.2 0.0 6.7e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 KFP01810.1 - 0.088 12.6 0.0 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain FAD_binding_1 PF00667.15 KFP01811.1 - 5.3e-82 274.5 0.0 8.2e-82 273.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFP01811.1 - 1.4e-38 132.1 1.6 2e-38 131.5 0.2 2.1 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.16 KFP01811.1 - 4.9e-23 81.7 0.1 4.8e-22 78.5 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFP01811.1 - 0.035 14.0 0.0 0.078 12.8 0.0 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain DUF3755 PF12579.3 KFP01811.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) TMPIT PF07851.8 KFP01812.1 - 6.3e-159 528.3 17.8 7.6e-159 528.1 12.4 1.0 1 0 0 1 1 1 1 TMPIT-like protein ALIX_LYPXL_bnd PF13949.1 KFP01812.1 - 0.049 12.5 4.7 0.068 12.1 3.2 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV IFT57 PF10498.4 KFP01812.1 - 0.063 12.0 4.9 0.083 11.6 3.4 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DSPc PF00782.15 KFP01813.1 - 3.8e-24 84.7 0.0 6e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFP01813.1 - 0.00017 21.9 0.1 0.0022 18.3 0.1 2.3 1 1 0 1 1 1 1 Rhodanese-like domain POP1 PF06978.6 KFP01813.1 - 0.18 11.4 0.6 0.31 10.6 0.4 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Ldh_1_N PF00056.18 KFP01814.1 - 1.3e-48 164.3 0.0 1.9e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFP01814.1 - 1.6e-39 135.4 0.0 3.9e-39 134.1 0.0 1.7 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.19 KFP01814.1 - 0.00016 21.9 0.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KFP01814.1 - 0.00071 18.3 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFP01814.1 - 0.0032 17.4 0.0 0.0081 16.1 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 KFP01814.1 - 0.0054 16.6 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.14 KFP01814.1 - 0.017 14.2 0.3 0.15 11.1 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_trans_1_4 PF13692.1 KFP01814.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 HSP20 PF00011.16 KFP01815.1 - 3.8e-14 52.3 0.3 5e-14 52.0 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Crystallin PF00525.13 KFP01815.1 - 0.13 12.5 0.9 0.25 11.5 0.6 1.7 1 1 0 1 1 1 0 Alpha crystallin A chain, N terminal YabP PF07873.6 KFP01815.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 YabP family 14-3-3 PF00244.15 KFP01816.1 - 1.3e-99 332.0 7.7 1.5e-99 331.8 5.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1987 PF09345.5 KFP01816.1 - 0.34 10.7 2.1 1.5 8.6 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1987) WWE PF02825.15 KFP01817.1 - 2.1e-31 107.1 0.1 6.7e-15 54.2 0.0 2.5 2 0 0 2 2 2 2 WWE domain zf-rbx1 PF12678.2 KFP01817.1 - 1.5e-05 24.9 2.7 1.5e-05 24.9 1.9 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP01817.1 - 4.6e-05 22.9 9.1 0.00011 21.7 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP01817.1 - 7.9e-05 22.4 9.3 7.9e-05 22.4 6.5 2.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFP01817.1 - 0.0089 15.7 8.6 0.0089 15.7 6.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFP01817.1 - 0.0099 15.8 2.6 0.0099 15.8 1.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFP01817.1 - 0.017 14.9 1.5 0.059 13.2 1.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MHC2-interact PF09307.5 KFP01818.1 - 0.11 12.3 0.0 10 5.9 0.0 2.2 2 0 0 2 2 2 0 CLIP, MHC2 interacting RasGAP PF00616.14 KFP01819.1 - 1.9e-42 145.2 0.0 2.4e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KFP01819.1 - 4.3e-39 132.2 0.1 1.3e-22 79.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain RNA_pol_L_2 PF13656.1 KFP01820.1 - 1.6e-29 101.1 0.1 1.9e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFP01820.1 - 3.8e-12 45.1 0.0 4.9e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SHNi-TPR PF10516.4 KFP01820.1 - 0.15 11.3 0.1 0.68 9.2 0.0 1.9 1 1 1 2 2 2 0 SHNi-TPR LRR_4 PF12799.2 KFP01821.1 - 2.5e-08 33.3 14.9 0.00015 21.2 2.1 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP01821.1 - 4.7e-07 29.4 10.5 0.00031 20.4 1.7 2.8 1 1 1 2 2 2 2 Leucine rich repeat WD40 PF00400.27 KFP01821.1 - 1.6e-06 27.7 1.4 1e-05 25.2 0.0 3.0 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.1 KFP01821.1 - 0.0042 16.5 0.1 1.6 8.1 0.1 2.3 2 0 0 2 2 2 2 PQQ-like domain LRR_7 PF13504.1 KFP01821.1 - 0.088 13.0 4.4 7.7 7.2 0.1 3.8 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 KFP01821.1 - 0.13 12.3 6.9 8.9 6.7 0.3 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 KFP01821.1 - 0.14 12.2 10.5 0.7 10.1 0.7 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat 2OG-FeII_Oxy_2 PF13532.1 KFP01822.1 - 4.7e-06 26.5 0.0 1e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFP01822.1 - 9.7e-05 22.5 0.1 0.0011 19.2 0.1 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Orai-1 PF07856.7 KFP01823.1 - 5.5e-79 263.8 5.7 6.5e-79 263.5 4.0 1.0 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF2207 PF09972.4 KFP01823.1 - 0.21 10.1 0.5 0.3 9.6 0.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-LITAF-like PF10601.4 KFP01823.1 - 0.38 10.6 5.3 8.5 6.3 0.0 3.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF1168 PF06658.7 KFP01824.1 - 6e-47 158.7 23.9 6.9e-47 158.5 16.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) rRNA_processing PF08524.6 KFP01824.1 - 0.16 11.7 28.5 0.21 11.3 19.7 1.1 1 0 0 1 1 1 0 rRNA processing BPL_N PF09825.4 KFP01824.1 - 0.39 9.4 6.7 0.49 9.1 4.6 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal FLO_LFY PF01698.11 KFP01824.1 - 0.57 8.9 16.9 0.68 8.7 11.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2413 PF10310.4 KFP01824.1 - 0.58 8.9 20.0 0.68 8.6 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RP-C_C PF11800.3 KFP01824.1 - 0.82 9.3 13.2 1.4 8.6 9.1 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region GAGA_bind PF06217.7 KFP01824.1 - 2.2 8.1 13.9 2.5 7.9 9.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_C58 PF03543.9 KFP01824.1 - 2.4 7.5 10.9 3.1 7.2 7.5 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Saw1 PF11561.3 KFP01824.1 - 3 7.1 12.5 3.6 6.9 8.7 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DDHD PF02862.12 KFP01824.1 - 3.5 7.3 15.0 4.4 7.0 10.4 1.1 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 KFP01824.1 - 4.6 6.9 13.8 5.7 6.6 9.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.5 KFP01824.1 - 7.3 6.5 24.6 11 5.9 17.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 KFP01824.1 - 8.4 5.1 20.8 10 4.9 14.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RNA_pol_3_Rpc31 PF11705.3 KFP01824.1 - 8.7 6.2 24.1 11 5.8 16.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CUT PF02376.10 KFP01825.1 - 4e-89 292.5 0.3 3.6e-28 97.2 0.0 4.1 3 0 0 3 3 3 3 CUT domain Homeobox PF00046.24 KFP01825.1 - 5.1e-15 54.8 0.8 5.1e-15 54.8 0.6 2.4 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFP01825.1 - 1.4e-06 27.8 0.2 6.7e-06 25.7 0.2 2.2 1 0 0 1 1 1 1 Homeobox KN domain NPV_P10 PF05531.7 KFP01825.1 - 0.02 15.1 12.8 0.024 14.8 0.9 3.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HOOK PF05622.7 KFP01825.1 - 0.047 11.5 38.2 0.11 10.3 26.5 1.6 1 0 0 1 1 1 0 HOOK protein EF-hand_1 PF00036.27 KFP01826.1 - 2.3e-14 51.5 3.9 5.1e-06 25.4 0.6 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KFP01826.1 - 6.7e-11 42.1 0.4 4.6e-06 26.6 0.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP01826.1 - 3e-10 39.0 3.3 2.9e-06 26.7 0.5 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFP01826.1 - 3e-09 36.3 1.5 0.0092 15.5 0.1 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KFP01826.1 - 4.4e-05 22.6 2.9 0.00032 19.8 1.1 2.7 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.5 KFP01826.1 - 0.00061 19.7 0.5 0.075 13.0 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.1 KFP01826.1 - 0.11 12.3 0.0 0.97 9.3 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain 3Beta_HSD PF01073.14 KFP01827.1 - 8.4e-51 172.3 0.0 9.5e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFP01827.1 - 7.2e-12 45.2 0.0 9.3e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFP01827.1 - 1.2e-08 34.2 0.0 1.4e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KFP01827.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain EMI PF07546.8 KFP01828.1 - 9.5e-26 90.0 11.3 1.7e-25 89.2 7.8 1.4 1 0 0 1 1 1 1 EMI domain Collagen PF01391.13 KFP01828.1 - 8.8e-20 70.0 75.8 2.8e-09 36.3 20.9 3.4 2 1 0 2 2 2 2 Collagen triple helix repeat (20 copies) Ras PF00071.17 KFP01829.1 - 1.1e-06 28.1 0.0 1.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01829.1 - 0.0076 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP01829.1 - 0.011 14.9 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family RILP PF11461.3 KFP01830.1 - 6.8e-18 64.5 5.8 6.8e-18 64.5 4.0 2.9 2 1 0 2 2 2 1 Rab interacting lysosomal protein DIRP PF06584.8 KFP01830.1 - 0.015 15.1 0.4 0.015 15.1 0.3 2.4 2 1 1 3 3 3 0 DIRP NPV_P10 PF05531.7 KFP01830.1 - 0.2 11.9 2.2 1.7 8.9 0.6 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Leu_zip PF15294.1 KFP01830.1 - 0.36 9.8 15.6 0.75 8.8 10.8 1.6 1 1 0 1 1 1 0 Leucine zipper BNIP3 PF06553.7 KFP01830.1 - 0.68 9.2 6.6 0.12 11.6 2.0 1.7 2 0 0 2 2 2 0 BNIP3 Takusan PF04822.8 KFP01830.1 - 0.88 9.3 11.5 0.18 11.5 0.6 2.6 2 1 0 2 2 2 0 Takusan DUF4228 PF14009.1 KFP01830.1 - 1.7 8.7 12.1 0.53 10.3 4.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4228) FAA_hydrolase_N PF09298.6 KFP01830.1 - 4.2 7.4 6.9 3 7.8 1.2 2.6 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal AATF-Che1 PF13339.1 KFP01830.1 - 7.1 6.7 15.8 0.89 9.7 4.6 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor PROCN PF08083.6 KFP01831.1 - 4.9e-224 743.2 6.7 8.5e-224 742.4 4.7 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KFP01831.1 - 2.7e-129 429.3 0.7 4.6e-129 428.5 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KFP01831.1 - 5.6e-94 311.8 2.2 1.1e-93 310.9 1.5 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KFP01831.1 - 1.8e-81 271.1 3.3 1.8e-81 271.1 2.3 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KFP01831.1 - 2.5e-70 234.3 0.0 5.7e-70 233.2 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 KFP01831.1 - 4.4e-52 175.0 0.0 9.9e-52 173.9 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 KFP01831.1 - 7.2e-45 150.7 0.4 1.8e-44 149.5 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 KFP01831.1 - 6.3e-14 51.6 0.0 3.2e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease WD40 PF00400.27 KFP01833.1 - 1.8e-17 62.4 8.5 4.4e-08 32.6 0.1 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KFP01833.1 - 0.0015 18.0 0.0 0.0075 15.7 0.0 2.1 1 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 KFP01833.1 - 0.0063 14.7 1.4 0.0097 14.0 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 BSP_II PF05432.6 KFP01833.1 - 0.044 13.0 10.6 0.072 12.3 7.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Serpin PF00079.15 KFP01834.1 - 4.2e-90 302.5 2.0 4.8e-90 302.3 1.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.15 KFP01835.1 - 6.4e-84 282.2 0.1 7.4e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Rep_fac-A_C PF08646.5 KFP01836.1 - 2.8e-54 182.7 11.2 1.8e-49 167.1 5.4 2.9 3 0 0 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KFP01836.1 - 3.8e-28 97.2 0.2 6.8e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KFP01836.1 - 4.6e-14 52.0 0.7 3.3e-12 46.0 0.0 3.3 2 1 1 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 KFP01836.1 - 0.042 13.9 0.1 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF223 FSH1 PF03959.8 KFP01837.1 - 2.8e-52 177.2 0.0 3.2e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFP01837.1 - 5.1e-07 29.5 1.0 7.7e-07 28.9 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP01837.1 - 2.6e-06 27.4 16.1 0.0066 16.3 6.7 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFP01837.1 - 0.0027 17.1 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 KFP01837.1 - 0.071 12.7 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase zf-C2H2 PF00096.21 KFP01838.1 - 7.2e-25 85.7 23.8 1.2e-05 25.3 1.0 6.0 5 0 0 5 5 5 5 Zinc finger, C2H2 type BTB PF00651.26 KFP01838.1 - 8.2e-25 86.9 0.0 1.2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KFP01838.1 - 9.4e-21 72.5 18.8 2e-05 24.6 0.2 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP01838.1 - 3.7e-20 71.1 28.4 7.4e-08 32.3 0.1 6.5 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP01838.1 - 3.2e-18 65.3 4.4 0.00049 20.1 0.2 5.7 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP01838.1 - 7.4e-12 45.0 13.8 0.013 15.6 0.3 6.1 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP01838.1 - 5.1e-09 35.7 16.7 0.008 16.0 0.1 5.6 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFP01838.1 - 5.9e-05 23.1 17.3 1.4 9.0 5.6 5.5 3 1 2 5 5 4 3 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFP01838.1 - 0.0054 16.8 12.2 0.16 12.1 0.5 3.4 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFP01838.1 - 0.025 14.8 14.3 0.66 10.3 0.8 4.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.5 KFP01838.1 - 0.036 14.0 13.5 1.2 9.1 1.5 4.7 4 1 0 4 4 4 0 Zinc ribbon domain SprT-like PF10263.4 KFP01838.1 - 0.061 12.9 7.9 2.3 7.8 2.2 2.7 1 1 2 3 3 3 0 SprT-like family GAGA PF09237.6 KFP01838.1 - 0.093 12.3 0.6 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 GAGA factor zf-UBP PF02148.14 KFP01838.1 - 0.27 11.3 11.5 1.8 8.7 0.1 3.5 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein C1_1 PF00130.17 KFP01838.1 - 0.55 10.0 8.5 0.45 10.2 0.8 3.6 4 0 0 4 4 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.17 KFP01838.1 - 0.76 9.9 9.4 0.22 11.6 0.2 3.3 2 1 2 4 4 4 0 LIM domain Prok-RING_1 PF14446.1 KFP01838.1 - 0.8 9.4 9.9 24 4.7 0.0 4.9 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.11 KFP01838.1 - 0.86 9.5 8.3 33 4.4 0.1 4.7 4 0 0 4 4 4 0 AN1-like Zinc finger C1_4 PF07975.7 KFP01838.1 - 0.95 9.5 9.5 6.6 6.8 0.7 3.2 3 0 0 3 3 3 0 TFIIH C1-like domain zf-HYPF PF07503.7 KFP01838.1 - 1.6 8.2 8.9 6.7 6.2 1.1 3.7 3 1 0 3 3 3 0 HypF finger zf-LYAR PF08790.6 KFP01838.1 - 1.6 8.4 0.0 1.6 8.4 0.0 3.5 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-FCS PF06467.9 KFP01838.1 - 1.8 8.2 6.2 3 7.5 0.2 3.4 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif A2L_zn_ribbon PF08792.5 KFP01838.1 - 8.5 5.9 7.1 12 5.4 0.0 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain EST1_DNA_bind PF10373.4 KFP01839.1 - 2.8e-78 262.9 0.0 6e-78 261.8 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.1 KFP01839.1 - 4.7e-23 81.7 0.0 4.7e-23 81.7 0.0 2.9 4 0 0 4 4 4 1 PIN domain EST1 PF10374.4 KFP01839.1 - 4.3e-22 78.5 0.2 1.2e-21 77.0 0.2 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 KFP01839.1 - 0.019 14.5 4.5 0.022 14.4 2.0 1.9 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KFP01839.1 - 0.33 10.9 1.7 4.4 7.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PALP PF00291.20 KFP01841.1 - 6.1e-77 258.8 0.7 7.3e-77 258.5 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3798 PF12683.2 KFP01841.1 - 0.036 13.1 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) DEDD_Tnp_IS110 PF01548.12 KFP01841.1 - 0.16 11.6 0.1 0.51 9.9 0.0 2.0 2 1 0 2 2 2 0 Transposase DUF663 PF04950.7 KFP01842.1 - 2.4e-123 410.8 0.0 4.9e-123 409.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFP01842.1 - 2.6e-19 68.5 0.0 5.2e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CDC45 PF02724.9 KFP01842.1 - 2 6.3 7.5 2.9 5.8 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF525 PF04379.9 KFP01843.1 - 2.7e-25 88.1 0.0 4.9e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF525) YccV-like PF08755.6 KFP01843.1 - 6.1e-05 22.8 1.2 0.0003 20.6 0.3 2.6 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Vma12 PF11712.3 KFP01844.1 - 7.5e-30 103.4 0.0 8.5e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Kinesin PF00225.18 KFP01845.1 - 2e-90 302.9 0.0 2.4e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF260 PF03195.9 KFP01845.1 - 0.01 16.0 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF260 Prp19 PF08606.6 KFP01845.1 - 0.036 13.8 0.2 0.068 12.9 0.2 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like Hemopexin PF00045.14 KFP01846.1 - 2.8e-49 164.6 19.1 2.7e-16 59.0 0.1 5.3 5 0 0 5 5 5 4 Hemopexin Somatomedin_B PF01033.12 KFP01846.1 - 2.1e-11 43.5 18.4 3.8e-11 42.7 12.8 1.4 1 0 0 1 1 1 1 Somatomedin B domain SAM_2 PF07647.12 KFP01847.1 - 1.1e-30 105.2 0.9 6e-17 61.2 0.1 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TIR_2 PF13676.1 KFP01847.1 - 1.6e-19 69.9 0.0 1.7e-18 66.6 0.0 2.5 2 0 0 2 2 2 1 TIR domain SAM_1 PF00536.25 KFP01847.1 - 3.4e-19 68.7 0.3 1.4e-13 50.7 0.1 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) DUF1863 PF08937.6 KFP01847.1 - 0.056 13.4 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) MFS_1 PF07690.11 KFP01848.1 - 2.8e-12 46.0 37.6 3.7e-11 42.3 26.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Na_sulph_symp PF00939.14 KFP01849.1 - 7.7e-122 407.5 17.5 9.8e-122 407.1 12.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFP01849.1 - 1.2e-09 37.2 33.9 0.00011 20.8 1.5 3.4 3 1 1 4 4 4 3 Citrate transporter Fork_head PF00250.13 KFP01850.1 - 2.2e-30 104.5 0.5 2.2e-30 104.5 0.4 2.0 2 0 0 2 2 2 1 Fork head domain GMP_PDE_delta PF05351.6 KFP01851.1 - 2.2e-81 271.2 3.1 2.4e-81 271.1 2.1 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit IIGP PF05049.8 KFP01851.1 - 0.11 11.2 0.2 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PIG-S PF10510.4 KFP01852.1 - 3.8e-124 415.1 0.3 4.8e-124 414.8 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein HrpB7 PF09486.5 KFP01852.1 - 3.2 7.6 8.4 0.093 12.6 0.4 2.2 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Glycolytic PF00274.14 KFP01853.1 - 3.2e-178 591.4 0.0 3.5e-178 591.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I YjcQ PF09639.5 KFP01853.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 YjcQ protein MAD PF05557.8 KFP01854.1 - 0.0091 14.1 10.9 0.012 13.7 7.5 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein TPR_MLP1_2 PF07926.7 KFP01854.1 - 0.0096 15.6 5.6 0.0096 15.6 3.9 1.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein CCDC155 PF14662.1 KFP01854.1 - 0.022 14.3 12.3 0.029 13.9 8.2 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 CALCOCO1 PF07888.6 KFP01854.1 - 0.029 12.6 10.3 0.032 12.5 7.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tail_P2_I PF09684.5 KFP01854.1 - 0.034 13.7 0.2 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) ATG16 PF08614.6 KFP01854.1 - 0.18 11.6 11.6 0.23 11.2 8.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.7 KFP01854.1 - 0.34 10.8 0.1 0.34 10.8 0.0 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat APG6 PF04111.7 KFP01854.1 - 2.7 6.9 10.7 2.9 6.8 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KFP01854.1 - 4 7.5 6.3 60 3.7 4.4 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 KFP01854.1 - 4.7 7.6 10.5 62 3.9 7.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Pkinase PF00069.20 KFP01855.1 - 2.4e-38 131.8 0.0 2.6e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01855.1 - 1.9e-18 66.4 0.0 2.2e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP01855.1 - 7.2e-06 25.1 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP01855.1 - 0.0035 16.4 0.2 0.0042 16.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFP01855.1 - 0.024 13.5 0.0 0.073 11.8 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.18 KFP01855.1 - 0.05 13.3 0.2 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family MIR PF02815.14 KFP01856.1 - 1.9e-09 37.3 0.0 3.3e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 MIR domain SH2_2 PF14633.1 KFP01857.1 - 8.2e-109 361.8 0.6 8.2e-109 361.8 0.4 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 KFP01857.1 - 1.7e-71 238.6 0.0 5.3e-71 237.0 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 KFP01857.1 - 3e-54 182.0 1.2 3e-54 182.0 0.8 3.7 2 1 1 3 3 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 KFP01857.1 - 2.5e-53 178.5 0.1 6e-53 177.3 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 KFP01857.1 - 1.6e-46 157.2 1.2 4.5e-46 155.7 0.8 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 KFP01857.1 - 7.1e-13 48.5 33.2 7.1e-13 48.5 23.0 8.0 7 1 2 9 9 7 2 Acidic N-terminal SPT6 Tex_N PF09371.5 KFP01857.1 - 4.6e-08 32.5 0.4 0.00092 18.5 0.0 3.0 3 0 0 3 3 3 2 Tex-like protein N-terminal domain SH2 PF00017.19 KFP01857.1 - 2.2e-06 27.3 0.0 5.9e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KFP01857.1 - 2.9e-06 27.1 0.0 2.1e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.18 KFP01857.1 - 4e-06 26.8 0.1 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain zf-C2H2_4 PF13894.1 KFP01857.1 - 0.12 12.7 0.3 0.38 11.2 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 KFP01857.1 - 0.2 11.2 0.4 0.51 9.9 0.3 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Ras PF00071.17 KFP01858.1 - 2.7e-46 156.9 0.1 3e-46 156.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP01858.1 - 2.4e-17 63.5 0.0 4.3e-17 62.7 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFP01858.1 - 2.3e-16 59.5 0.0 2.8e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP01858.1 - 9.9e-07 28.1 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP01858.1 - 2.1e-06 27.6 0.0 3.4e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP01858.1 - 0.00013 21.4 0.0 0.0055 16.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP01858.1 - 0.00015 21.0 0.0 0.00018 20.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KFP01858.1 - 0.0012 18.7 0.0 0.45 10.3 0.0 2.7 2 1 1 3 3 3 1 Dynamin family AAA_14 PF13173.1 KFP01858.1 - 0.0038 17.1 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KFP01858.1 - 0.031 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KFP01858.1 - 0.032 13.6 0.1 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KFP01858.1 - 0.086 12.3 0.0 0.41 10.1 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TRAM_LAG1_CLN8 PF03798.11 KFP01859.1 - 7e-18 64.8 12.3 8.5e-18 64.6 8.5 1.0 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.20 KFP01860.1 - 1.5e-59 201.2 0.1 2.7e-59 200.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.13 KFP01860.1 - 2.6e-46 155.5 24.3 4.1e-14 52.5 0.4 8.2 7 2 1 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.12 KFP01860.1 - 6.9e-42 143.3 0.0 1.1e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.1 KFP01860.1 - 3.7e-19 67.8 31.0 6e-06 25.7 0.2 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.1 KFP01860.1 - 3.9e-05 22.7 0.0 5.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP01860.1 - 0.039 13.6 0.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KFP01860.1 - 0.18 10.8 0.2 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MATH PF00917.21 KFP01861.1 - 2.8e-13 50.1 0.0 3.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 MATH domain Smg4_UPF3 PF03467.10 KFP01861.1 - 0.065 13.2 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Smg-4/UPF3 family FAM222A PF15258.1 KFP01862.1 - 6.9e-248 823.8 41.5 2.5e-247 822.0 28.8 1.7 1 1 0 1 1 1 1 Protein family of FAM222A DUF2981 PF11200.3 KFP01862.1 - 5 6.0 9.8 3.6e+02 -0.0 6.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) MMR_HSR1 PF01926.18 KFP01863.1 - 1.6e-20 73.1 0.0 2.5e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFP01863.1 - 7.9e-11 42.0 0.5 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Dynamin family Miro PF08477.8 KFP01863.1 - 1.6e-09 38.2 0.0 2.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KFP01863.1 - 3.5e-09 36.1 0.0 5.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFP01863.1 - 3.5e-09 36.3 0.0 2.1e-06 27.2 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KFP01863.1 - 6.2e-08 32.0 0.0 9.4e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family KH_2 PF07650.12 KFP01863.1 - 1.5e-07 30.8 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 KH domain AAA_28 PF13521.1 KFP01863.1 - 0.0003 20.7 0.1 0.015 15.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain cobW PF02492.14 KFP01863.1 - 0.0003 20.2 0.6 0.0037 16.7 0.1 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GBP PF02263.14 KFP01863.1 - 0.00052 19.1 0.2 0.014 14.4 0.1 2.1 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Ras PF00071.17 KFP01863.1 - 0.00063 19.1 0.0 0.0028 17.0 0.0 1.9 1 1 0 1 1 1 1 Ras family DUF258 PF03193.11 KFP01863.1 - 0.00086 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 KH_1 PF00013.24 KFP01863.1 - 0.0022 17.6 0.1 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 KH domain AAA_17 PF13207.1 KFP01863.1 - 0.0028 18.4 0.0 0.0056 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 KFP01863.1 - 0.0034 16.6 0.3 0.065 12.4 0.2 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family KH_3 PF13014.1 KFP01863.1 - 0.0047 16.5 0.3 0.0093 15.5 0.2 1.5 1 0 0 1 1 1 1 KH domain ATP_bind_1 PF03029.12 KFP01863.1 - 0.0049 16.4 0.1 0.034 13.7 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.15 KFP01863.1 - 0.0092 14.7 0.2 1.3 7.6 0.1 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.1 KFP01863.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 KFP01863.1 - 0.059 12.8 0.0 4.5 6.7 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Band_7 PF01145.20 KFP01864.1 - 6e-19 68.6 0.1 6e-19 68.6 0.0 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFP01864.1 - 0.012 15.1 3.0 0.026 14.0 0.1 2.5 3 0 0 3 3 3 0 SPFH domain-Band 7 family Sds3 PF08598.6 KFP01864.1 - 2.2 7.7 8.5 5.1 6.5 5.9 1.7 1 0 0 1 1 1 0 Sds3-like Sushi PF00084.15 KFP01866.1 - 2.2e-33 114.3 14.9 8.8e-10 38.7 1.8 4.3 4 0 0 4 4 4 4 Sushi domain (SCR repeat) CUB PF00431.15 KFP01866.1 - 4.6e-17 62.0 0.0 6.4e-16 58.4 0.0 2.4 2 0 0 2 2 2 1 CUB domain SKG6 PF08693.5 KFP01866.1 - 0.11 11.8 1.0 0.21 10.9 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain cEGF PF12662.2 KFP01866.1 - 3.8 7.2 9.0 7.5 6.2 0.1 3.8 4 1 0 4 4 4 0 Complement Clr-like EGF-like Myosin_head PF00063.16 KFP01868.1 - 1e-72 245.2 6.9 5.8e-40 137.0 0.0 4.4 5 0 0 5 5 3 3 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFP01868.1 - 9.6e-34 116.2 147.4 9.6e-34 116.2 102.2 2.7 1 1 1 2 2 2 1 Myosin tail PDZ PF00595.19 KFP01868.1 - 6.2e-10 39.1 0.0 1.9e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) IQ PF00612.22 KFP01868.1 - 0.00015 21.0 3.0 0.00024 20.4 0.1 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF869 PF05911.6 KFP01868.1 - 0.013 13.7 126.9 0.011 14.0 35.7 4.0 2 1 2 4 4 4 0 Plant protein of unknown function (DUF869) PDZ_2 PF13180.1 KFP01868.1 - 0.033 14.0 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 PDZ domain Reo_sigmaC PF04582.7 KFP01868.1 - 0.051 12.7 44.2 0.035 13.2 1.2 6.3 2 1 3 6 6 6 0 Reovirus sigma C capsid protein AAA_29 PF13555.1 KFP01868.1 - 0.074 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KFP01868.1 - 0.15 12.2 0.1 0.15 12.2 0.1 3.9 4 2 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.12 KFP01868.1 - 0.3 10.5 6.1 0.95 8.9 0.2 3.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KFP01868.1 - 0.81 10.5 0.0 0.81 10.5 0.0 4.9 3 2 0 3 3 1 0 AAA domain Crystall PF00030.14 KFP01869.1 - 1.2e-59 198.1 6.8 4e-30 103.5 0.2 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin NUFIP2 PF15293.1 KFP01870.1 - 1e-292 972.3 23.7 1.2e-292 972.1 16.4 1.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 Pkinase PF00069.20 KFP01871.1 - 2.7e-65 220.1 0.0 2.7e-65 220.1 0.0 2.5 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01871.1 - 9.8e-45 152.6 1.3 1.9e-44 151.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFP01871.1 - 0.0026 17.5 1.9 0.0051 16.5 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family AAA-ATPase_like PF09820.4 KFP01871.1 - 0.005 16.0 6.1 0.005 16.0 4.3 2.8 2 0 0 2 2 2 1 Predicted AAA-ATPase Abhydrolase_6 PF12697.2 KFP01872.1 - 3.8e-08 33.4 0.3 7.5e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family GIT1_C PF12205.3 KFP01873.1 - 5.8e-62 206.9 0.4 2.2e-61 205.1 0.2 2.1 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_SHD PF08518.6 KFP01873.1 - 1.1e-27 95.0 6.9 3.8e-14 51.7 0.7 2.9 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT ArfGap PF01412.13 KFP01873.1 - 1.4e-19 69.9 0.0 4.1e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFP01873.1 - 1.3e-14 54.2 0.0 4.7e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01873.1 - 8.7e-10 37.9 0.2 4.8e-05 22.9 0.0 4.1 4 0 0 4 4 3 1 Ankyrin repeat Ank_5 PF13857.1 KFP01873.1 - 3.4e-08 33.4 0.0 2.3e-07 30.8 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP01873.1 - 2e-07 31.3 0.0 0.00018 21.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01873.1 - 4.5e-05 23.2 0.0 0.92 9.9 0.0 4.2 4 0 0 4 4 3 1 Ankyrin repeat DUF904 PF06005.7 KFP01873.1 - 0.0028 17.8 0.5 0.012 15.8 0.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF4319 PF14203.1 KFP01873.1 - 0.0082 15.6 1.8 0.015 14.8 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4319) Spc24 PF08286.6 KFP01873.1 - 0.035 13.8 1.5 0.25 11.0 0.1 2.7 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 Sipho_Gp157 PF05565.6 KFP01873.1 - 0.037 13.6 0.8 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 DUF972 PF06156.8 KFP01873.1 - 0.038 14.3 0.3 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 KFP01873.1 - 0.08 12.6 3.8 0.24 11.1 2.6 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF2580 PF10824.3 KFP01873.1 - 0.37 11.1 3.0 0.5 10.7 0.0 2.8 3 1 0 3 3 2 0 Protein of unknown function (DUF2580) DUF3347 PF11827.3 KFP01873.1 - 0.59 10.1 3.7 0.38 10.7 0.9 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3347) DivIC PF04977.10 KFP01873.1 - 1.4 8.4 8.0 0.69 9.4 1.6 2.8 1 1 1 2 2 2 0 Septum formation initiator SlyX PF04102.7 KFP01873.1 - 2.7 8.4 7.0 0.39 11.1 1.1 2.6 2 0 0 2 2 1 0 SlyX GPCR_chapero_1 PF11904.3 KFP01874.1 - 6.8e-110 366.9 0.0 8.9e-110 366.6 0.0 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 KFP01874.1 - 2.5e-13 50.1 0.0 5.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01874.1 - 8.3e-11 41.1 0.0 8e-09 34.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KFP01874.1 - 1.4e-09 37.9 0.0 5.7e-09 35.9 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP01874.1 - 6.4e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01874.1 - 3.1e-07 29.9 0.0 0.00017 21.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat UIM PF02809.15 KFP01874.1 - 0.092 12.3 20.2 0.88 9.3 1.7 3.7 3 0 0 3 3 3 0 Ubiquitin interaction motif DUF1900 PF08954.6 KFP01875.1 - 2e-57 192.5 0.0 3.6e-57 191.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KFP01875.1 - 2.3e-34 116.8 0.0 4.9e-34 115.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KFP01875.1 - 4.9e-23 80.1 4.4 3.9e-08 32.8 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat DSPc PF00782.15 KFP01876.1 - 1e-34 118.9 0.0 3.1e-34 117.4 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.6 KFP01876.1 - 2.8e-15 55.8 3.8 5.9e-15 54.7 2.7 1.6 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.22 KFP01876.1 - 0.01 15.2 0.0 0.034 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2040 PF09745.4 KFP01877.1 - 3.6e-36 123.8 26.4 3.6e-36 123.8 18.3 5.5 3 1 2 5 5 5 1 Coiled-coil domain-containing protein 55 (DUF2040) SNF PF00209.13 KFP01878.1 - 4.1e-229 761.3 36.0 4.7e-229 761.1 24.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family 5HT_transporter PF03491.8 KFP01878.1 - 6.6e-06 26.1 0.5 1.5e-05 24.9 0.3 1.6 1 0 0 1 1 1 1 Serotonin (5-HT) neurotransmitter transporter, N-terminus Peptidase_C1_2 PF03051.10 KFP01879.1 - 2.3e-203 675.6 0.5 2.6e-203 675.4 0.3 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KFP01879.1 - 6.8e-07 29.3 1.0 0.0069 16.2 0.1 2.7 3 0 0 3 3 3 2 Papain family cysteine protease Ig_2 PF13895.1 KFP01880.1 - 2.4e-18 66.0 2.6 1.2e-14 54.2 0.7 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP01880.1 - 7.2e-18 64.2 0.7 1.4e-16 60.1 0.2 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP01880.1 - 7.4e-17 61.6 3.0 4e-11 43.2 0.5 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP01880.1 - 7.3e-13 48.4 3.6 6.6e-11 42.1 0.5 3.2 2 1 1 3 3 3 1 Immunoglobulin domain V-set PF07686.12 KFP01880.1 - 2.9e-11 43.2 4.3 2e-10 40.5 1.2 2.9 2 2 0 2 2 2 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP01880.1 - 9.3e-05 22.2 4.0 0.0006 19.6 1.0 2.6 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFP01880.1 - 0.013 15.5 2.5 0.14 12.2 1.3 2.7 2 1 1 3 3 3 0 Immunoglobulin C1-set domain V-set_CD47 PF08204.6 KFP01880.1 - 0.037 13.7 0.3 0.09 12.5 0.2 1.6 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Herpes_gE PF02480.11 KFP01880.1 - 0.076 11.2 1.0 0.16 10.1 0.6 1.9 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Peptidase_M14 PF00246.19 KFP01881.1 - 1.8e-172 572.3 0.0 2.8e-85 286.3 0.0 3.1 3 0 0 3 3 3 3 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 KFP01881.1 - 2.6e-36 123.5 3.1 4e-13 49.2 0.0 3.5 3 0 0 3 3 3 3 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFP01881.1 - 6.7e-21 74.1 0.1 5.6e-07 29.5 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4480) PEGA PF08308.6 KFP01881.1 - 4.6e-07 29.5 0.0 0.15 11.8 0.0 3.6 3 0 0 3 3 3 2 PEGA domain phage_tail_N PF08400.5 KFP01881.1 - 1.5e-06 27.9 1.6 0.51 10.0 0.2 3.4 3 0 0 3 3 3 3 Prophage tail fibre N-terminal AstE_AspA PF04952.9 KFP01881.1 - 0.0032 16.4 0.1 0.071 11.9 0.0 2.4 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family V-SNARE_C PF12352.3 KFP01882.1 - 5.7e-22 77.5 3.6 5.7e-22 77.5 2.5 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFP01882.1 - 0.0025 17.4 1.1 0.015 14.9 0.2 2.2 2 0 0 2 2 2 1 Sec20 Dispanin PF04505.7 KFP01883.1 - 2.6e-26 90.9 0.2 3.5e-26 90.5 0.2 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4190 PF13828.1 KFP01883.1 - 0.00019 20.9 5.8 0.0017 17.8 3.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4190) DUF2852 PF11014.3 KFP01883.1 - 0.019 14.9 0.4 0.037 13.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) RhoGAP PF00620.22 KFP01884.1 - 3.8e-48 162.9 0.0 8.8e-48 161.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.15 KFP01884.1 - 2.8e-35 121.8 2.4 5.6e-35 120.8 1.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFP01884.1 - 5.4e-17 61.8 1.8 6.4e-17 61.6 0.3 1.9 2 0 0 2 2 2 1 PH domain C2 PF00168.25 KFP01884.1 - 5.7e-11 42.1 0.0 1.7e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain Tim17 PF02466.14 KFP01885.1 - 3.2e-38 130.6 4.2 3.5e-38 130.5 2.9 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CH PF00307.26 KFP01886.1 - 3.7e-24 84.8 2.1 9.8e-24 83.4 0.1 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP01886.1 - 5.1e-09 35.6 0.5 2e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 CAMSAP CH domain TPR_MLP1_2 PF07926.7 KFP01886.1 - 0.0049 16.5 11.0 0.0049 16.5 7.6 6.3 3 1 3 6 6 6 3 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 KFP01886.1 - 0.11 12.2 0.1 0.11 12.2 0.1 6.7 2 1 6 8 8 8 0 Plant protein of unknown function (DUF641) 7tm_1 PF00001.16 KFP01887.1 - 1.6e-63 214.2 15.9 1.9e-63 213.9 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP01887.1 - 3.5e-14 52.6 17.0 4e-08 32.7 3.3 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP01887.1 - 0.00018 20.7 9.5 0.00018 20.7 6.6 2.5 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3_C PF11970.3 KFP01887.1 - 0.03 14.0 0.3 0.11 12.3 0.2 2.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term SWIM PF04434.12 KFP01888.1 - 9.5e-07 28.1 5.8 1.8e-06 27.2 4.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger TPR_12 PF13424.1 KFP01889.1 - 1.7e-27 95.1 20.9 3.3e-15 55.7 0.4 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFP01889.1 - 5.7e-15 53.9 15.9 0.0062 16.3 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFP01889.1 - 3.2e-14 52.3 13.3 0.00027 20.7 0.0 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFP01889.1 - 3.4e-12 45.8 17.0 1.8e-07 30.6 0.7 4.2 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFP01889.1 - 8.9e-11 40.9 19.2 0.012 15.2 0.2 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFP01889.1 - 2e-09 37.8 17.1 3e-05 24.5 1.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP01889.1 - 1.7e-08 34.3 16.4 0.65 10.7 0.1 6.3 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP01889.1 - 4.7e-06 26.8 22.5 0.0019 18.5 0.2 4.7 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFP01889.1 - 8.5e-06 25.5 10.8 0.67 10.2 0.0 6.0 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFP01889.1 - 2.4e-05 23.7 12.5 0.27 11.1 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFP01889.1 - 0.00011 22.3 0.0 2 9.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP01889.1 - 0.00012 22.1 15.2 0.013 15.6 0.2 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFP01889.1 - 0.00022 20.7 15.4 0.99 9.3 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat PE-PPE PF08237.6 KFP01889.1 - 0.0037 16.7 0.0 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain DUF3613 PF12266.3 KFP01889.1 - 0.041 13.4 0.6 0.15 11.5 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Apc5 PF12862.2 KFP01889.1 - 0.065 13.0 12.2 0.11 12.3 0.6 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 PPR PF01535.15 KFP01889.1 - 0.33 11.0 1.5 4.8 7.3 0.1 3.3 4 0 0 4 4 3 0 PPR repeat Myb_DNA-binding PF00249.26 KFP01890.1 - 2e-18 66.1 0.3 1.5e-11 44.1 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain PIG-L PF02585.12 KFP01891.1 - 2.6e-10 40.9 0.0 4.8e-10 40.0 0.0 1.4 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase LPAM_1 PF08139.7 KFP01891.1 - 7.7 6.9 5.7 2.7 8.3 0.4 2.7 3 0 0 3 3 3 0 Prokaryotic membrane lipoprotein lipid attachment site GFA PF04828.9 KFP01892.1 - 4.1e-12 45.8 1.7 4.1e-12 45.8 1.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.14 KFP01892.1 - 0.041 13.6 0.3 0.041 13.6 0.2 1.8 2 0 0 2 2 2 0 Ribosomal protein L37e ubiquitin PF00240.18 KFP01893.1 - 1.3e-133 434.5 16.7 1.2e-34 117.4 0.3 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 KFP01893.1 - 1.6e-77 255.1 15.1 1.1e-19 69.8 0.3 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFP01893.1 - 6.8e-26 90.3 5.2 3.6e-05 23.9 0.1 5.6 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFP01893.1 - 5.3e-18 65.2 0.0 0.0028 17.3 0.0 4.1 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KFP01893.1 - 8.8e-15 54.5 1.8 0.05 13.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFP01893.1 - 2.9e-13 49.8 0.3 0.22 11.7 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 KFP01893.1 - 9.5e-13 47.8 1.2 0.079 12.8 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG DUF2870 PF11069.3 KFP01893.1 - 5.2e-10 39.2 0.0 1.4 8.9 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 KFP01893.1 - 1.1e-07 31.5 1.8 5.1 6.9 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain USP7_C2 PF14533.1 KFP01893.1 - 6e-06 25.8 3.4 5.6 6.3 0.0 4.0 2 1 0 4 4 4 3 Ubiquitin-specific protease C-terminal CTDII PF01556.13 KFP01893.1 - 0.00013 21.7 12.6 2.5 8.0 0.2 4.3 2 1 2 4 4 4 3 DnaJ C terminal domain FERM_N PF09379.5 KFP01893.1 - 0.00045 20.2 3.8 39 4.3 0.0 5.4 4 3 0 4 4 4 0 FERM N-terminal domain YfmQ PF10787.4 KFP01893.1 - 0.0019 17.5 0.3 48 3.2 0.0 4.0 4 0 0 4 4 4 0 Uncharacterised protein from bacillus cereus group Plexin_cytopl PF08337.7 KFP01893.1 - 0.0036 15.6 9.0 5.5 5.1 0.1 5.1 4 3 0 4 4 4 3 Plexin cytoplasmic RasGAP domain GDYXXLXY PF14345.1 KFP01893.1 - 0.098 12.5 0.8 2.1e+02 1.7 0.0 4.1 4 0 0 4 4 4 0 GDYXXLXY protein GABP-alpha PF11620.3 KFP01893.1 - 0.23 11.4 2.4 45 4.1 0.1 3.5 3 1 1 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 KFP01893.1 - 0.28 11.1 4.6 1.5e+02 2.4 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) YajC PF02699.10 KFP01893.1 - 0.65 9.7 8.0 53 3.5 0.0 4.0 4 0 0 4 4 4 0 Preprotein translocase subunit Ank_2 PF12796.2 KFP01894.1 - 3.3e-24 85.0 0.8 2.6e-12 46.9 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01894.1 - 1.9e-17 62.0 0.5 7.8e-08 31.7 0.1 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 KFP01894.1 - 2.2e-17 61.3 0.0 1.6e-06 27.7 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KFP01894.1 - 7.6e-15 54.6 0.4 0.00014 22.0 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP01894.1 - 2.8e-11 43.6 0.1 0.0039 17.6 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFP01894.1 - 0.0079 15.4 23.6 0.027 13.7 16.4 1.9 1 1 0 1 1 1 1 Ion transport protein P2X_receptor PF00864.14 KFP01895.1 - 3.6e-173 575.4 0.5 4.3e-173 575.2 0.4 1.0 1 0 0 1 1 1 1 ATP P2X receptor Rab5ip PF07019.7 KFP01896.1 - 1.5e-25 89.1 6.6 1.6e-25 88.9 4.6 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF4271 PF14093.1 KFP01896.1 - 0.0089 15.7 4.4 0.01 15.5 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DUF606 PF04657.8 KFP01896.1 - 0.05 13.6 3.2 0.064 13.3 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF606 Peptidase_U4 PF03419.8 KFP01896.1 - 0.069 12.2 0.5 0.067 12.2 0.4 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA PDZ PF00595.19 KFP01897.1 - 9.9e-20 70.5 0.2 1.2e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP01897.1 - 1.2e-11 44.3 0.3 1.7e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFP01897.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.5 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain PQ-loop PF04193.9 KFP01898.1 - 2.4e-24 84.6 9.6 4.6e-19 67.7 2.5 2.6 2 0 0 2 2 2 2 PQ loop repeat FGGY_N PF00370.16 KFP01899.1 - 4.2e-26 91.7 0.0 7.7e-25 87.6 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KFP01899.1 - 0.0097 15.2 0.0 0.017 14.4 0.0 1.5 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF1537 PF07005.6 KFP01899.1 - 0.071 12.7 2.2 0.3 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF1537 DUF4445 PF14574.1 KFP01899.1 - 0.074 11.2 0.1 0.12 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) Ank PF00023.25 KFP01900.1 - 6.1e-18 63.6 0.2 7.9e-09 34.8 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFP01900.1 - 1.5e-15 57.3 1.0 1.1e-06 28.8 0.1 3.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFP01900.1 - 1.9e-13 49.1 0.2 2.1e-06 27.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFP01900.1 - 4.2e-12 45.8 0.2 5.1e-05 23.3 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP01900.1 - 6.1e-09 36.1 0.2 0.00012 22.5 0.0 3.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFP01900.1 - 6.9e-06 25.4 20.4 2.6e-05 23.5 14.2 1.9 1 1 0 1 1 1 1 Ion transport protein Ank_2 PF12796.2 KFP01901.1 - 2.9e-20 72.4 8.1 8.7e-10 38.8 1.4 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01901.1 - 1.9e-17 62.1 0.2 6.7e-05 22.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFP01901.1 - 3.3e-15 55.7 0.0 0.0017 18.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01901.1 - 2.3e-13 48.9 0.0 0.00064 19.7 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KFP01901.1 - 1.9e-10 40.9 0.7 0.011 16.2 0.0 5.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) DUF4065 PF13274.1 KFP01901.1 - 0.058 14.1 0.0 0.46 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) DUF2229 PF09989.4 KFP01901.1 - 0.071 12.5 0.7 0.13 11.7 0.5 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) IL4 PF00727.13 KFP01901.1 - 0.083 12.7 1.7 0.12 12.1 0.4 1.9 2 0 0 2 2 2 0 Interleukin 4 AstE_AspA PF04952.9 KFP01902.1 - 5e-60 202.8 0.0 5.7e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family L_HGMIC_fpl PF10242.4 KFP01904.1 - 4.2e-14 52.9 0.5 5.2e-14 52.6 0.3 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein RGS PF00615.14 KFP01905.1 - 7.3e-31 106.7 2.1 2.8e-12 46.7 0.1 3.4 3 0 0 3 3 3 3 Regulator of G protein signaling domain WD40 PF00400.27 KFP01906.1 - 1.5e-67 221.2 16.2 6.2e-13 48.0 0.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.7 KFP01906.1 - 1.6e-17 63.2 0.1 3.6e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 NLE (NUC135) domain Nup160 PF11715.3 KFP01906.1 - 3.1e-06 25.6 1.0 0.048 11.7 0.0 3.8 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFP01906.1 - 0.00016 20.5 2.0 2.1 6.9 0.1 3.6 2 1 2 4 4 4 3 Nup133 N terminal like eIF2A PF08662.6 KFP01906.1 - 0.00023 20.9 0.0 0.4 10.3 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KFP01906.1 - 0.0066 14.7 0.0 0.025 12.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) PD40 PF07676.7 KFP01906.1 - 0.016 14.8 0.4 0.45 10.2 0.1 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Lipase_GDSL_2 PF13472.1 KFP01907.1 - 0.00026 21.1 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GDPD PF03009.12 KFP01908.1 - 1.8e-21 76.8 0.0 1.3e-18 67.4 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family NigD PF12667.2 KFP01908.1 - 0.094 12.5 1.8 0.45 10.2 1.2 2.0 1 1 0 1 1 1 0 NigD-like protein DUF4131 PF13567.1 KFP01908.1 - 2 7.8 7.9 0.65 9.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ESSS PF10183.4 KFP01908.1 - 3.3 8.1 8.1 0.13 12.6 1.0 2.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TMEM190 PF15431.1 KFP01908.1 - 5.8 6.8 6.7 1.3 8.9 1.6 2.1 2 0 0 2 2 2 0 Transmembrane protein 190 Kelch_1 PF01344.20 KFP01911.1 - 1.1e-55 184.9 2.3 1.1e-12 47.2 0.0 6.8 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFP01911.1 - 1.4e-36 123.1 8.2 5.4e-09 35.8 0.1 6.4 4 1 2 6 6 6 6 Kelch motif BACK PF07707.10 KFP01911.1 - 6.5e-33 112.6 0.2 2.1e-32 111.0 0.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFP01911.1 - 9e-30 102.9 0.0 5.6e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KFP01911.1 - 5.7e-28 95.5 7.4 9e-05 22.0 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFP01911.1 - 5.5e-26 90.0 5.6 7e-05 22.5 0.0 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KFP01911.1 - 3.4e-21 74.8 1.6 0.0019 18.2 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP01911.1 - 1.3e-15 56.9 10.3 0.0073 16.2 0.0 6.1 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.3 KFP01911.1 - 1.6e-05 24.2 0.0 3.8e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) STOP PF05217.7 KFP01912.1 - 2.9e-22 79.4 4.8 3e-15 56.5 0.8 2.9 2 1 0 2 2 2 2 STOP protein Clr5 PF14420.1 KFP01912.1 - 1.1 9.1 3.7 1.4 8.8 0.3 2.7 3 0 0 3 3 3 0 Clr5 domain DAGAT PF03982.8 KFP01913.1 - 3.8e-117 390.2 0.0 4.5e-117 389.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 KFP01913.1 - 0.024 14.0 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase DAGAT PF03982.8 KFP01914.1 - 1.8e-142 473.3 0.0 2.1e-142 473.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 KFP01914.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase wnt PF00110.14 KFP01916.1 - 3.6e-106 354.8 17.7 4.1e-106 354.6 12.3 1.0 1 0 0 1 1 1 1 wnt family THAP PF05485.7 KFP01917.1 - 7e-18 64.5 3.4 1.6e-17 63.4 2.3 1.6 1 0 0 1 1 1 1 THAP domain DUF4371 PF14291.1 KFP01917.1 - 2.8e-16 59.7 0.0 6.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4371) Dimer_Tnp_hAT PF05699.9 KFP01917.1 - 5.8e-10 38.6 0.1 1.4e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Guanylate_cyc PF00211.15 KFP01918.1 - 2.5e-64 216.0 0.0 7.1e-64 214.5 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain ANF_receptor PF01094.23 KFP01918.1 - 2.7e-51 174.4 0.0 3.8e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Pkinase_Tyr PF07714.12 KFP01918.1 - 2.4e-35 121.8 0.0 3.7e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP01918.1 - 5e-27 94.6 0.0 8.5e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.9 KFP01918.1 - 1.2e-05 24.6 1.5 1.8e-05 24.0 1.0 1.3 1 0 0 1 1 1 1 Heme NO binding associated Peripla_BP_6 PF13458.1 KFP01918.1 - 0.0012 18.2 0.0 0.0031 16.9 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein Kinase-like PF14531.1 KFP01918.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Baculo_p33 PF05214.7 KFP01918.1 - 0.052 12.8 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Baculovirus P33 ALIX_LYPXL_bnd PF13949.1 KFP01918.1 - 0.091 11.7 0.4 0.16 10.8 0.3 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV LRR_8 PF13855.1 KFP01919.1 - 3.8e-37 125.8 24.5 6.1e-12 45.1 2.5 5.8 1 1 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 KFP01919.1 - 3.8e-25 84.0 24.0 0.0032 17.2 0.2 10.5 10 0 0 10 10 10 7 Leucine Rich Repeat LRR_4 PF12799.2 KFP01919.1 - 2.4e-23 81.2 34.7 1.4e-06 27.7 0.5 6.6 2 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP01919.1 - 3.9e-12 46.0 0.1 2e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFP01919.1 - 9.1e-12 43.1 26.8 0.34 11.2 0.0 9.7 10 0 0 10 10 10 3 Leucine rich repeat LRR_6 PF13516.1 KFP01919.1 - 5.7e-11 41.2 33.2 0.87 9.8 0.0 10.2 9 1 2 11 11 11 6 Leucine Rich repeat LRRNT PF01462.13 KFP01919.1 - 0.066 12.7 2.1 0.2 11.1 0.5 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain S_tail_recep_bd PF14928.1 KFP01920.1 - 4.9 7.3 6.6 7.9 6.7 1.0 2.0 1 1 1 2 2 2 0 Short tail fibre protein receptor-binding domain Ceramidase PF05875.7 KFP01923.1 - 1.9e-81 273.0 17.8 2.3e-81 272.8 12.3 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_C2 PF00648.16 KFP01924.1 - 2.3e-111 371.5 1.9 3.4e-111 371.0 1.3 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFP01924.1 - 2.5e-45 153.7 0.0 4e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.25 KFP01924.1 - 1.1e-14 54.0 0.0 2.8e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 KFP01924.1 - 0.027 13.9 0.0 1.5 8.3 0.0 3.1 3 0 0 3 3 3 0 CEP76 C2 domain Myosin_head PF00063.16 KFP01925.1 - 5.2e-231 768.4 1.0 7.4e-231 767.9 0.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.12 KFP01925.1 - 2.1e-76 253.3 0.1 7.3e-37 125.8 0.0 3.1 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.13 KFP01925.1 - 1.2e-22 80.4 2.5 5.4e-16 58.9 0.0 4.0 3 0 0 3 3 3 2 FERM central domain IQ PF00612.22 KFP01925.1 - 3.5e-18 63.4 10.2 0.0001 21.6 0.1 5.0 4 0 0 4 4 4 4 IQ calmodulin-binding motif FERM_N PF09379.5 KFP01925.1 - 2e-10 40.5 0.2 0.00019 21.4 0.0 2.8 2 0 0 2 2 2 2 FERM N-terminal domain RA PF00788.18 KFP01925.1 - 0.0017 18.8 0.2 0.67 10.4 0.0 3.1 3 0 0 3 3 2 1 Ras association (RalGDS/AF-6) domain AAA_16 PF13191.1 KFP01925.1 - 0.017 15.1 0.7 0.11 12.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain PID PF00640.18 KFP01925.1 - 0.021 14.7 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.1 KFP01925.1 - 0.029 13.9 0.0 0.15 11.6 0.0 2.3 1 0 0 1 1 1 0 Variant SH3 domain AAA_22 PF13401.1 KFP01925.1 - 0.032 14.3 0.0 0.32 11.1 0.0 2.8 2 1 0 3 3 2 0 AAA domain SH3_1 PF00018.23 KFP01925.1 - 0.034 13.5 0.3 0.74 9.2 0.1 2.9 2 0 0 2 2 2 0 SH3 domain SH3_2 PF07653.12 KFP01925.1 - 0.065 12.7 0.6 1.2 8.6 0.0 2.8 2 0 0 2 2 2 0 Variant SH3 domain DUF3752 PF12572.3 KFP01925.1 - 0.1 12.7 10.5 0.27 11.3 7.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ABC_tran PF00005.22 KFP01925.1 - 0.24 11.6 2.4 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter GDPD PF03009.12 KFP01926.1 - 9.8e-19 67.8 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.20 KFP01927.1 - 8.8e-73 244.6 0.0 1.9e-72 243.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01927.1 - 3.6e-47 160.6 0.0 5.7e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFP01927.1 - 2.5e-24 85.4 0.4 1e-23 83.4 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KFP01927.1 - 2.6e-08 33.1 0.0 8e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFP01927.1 - 0.0015 18.2 0.0 0.022 14.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DSHCT PF08148.7 KFP01927.1 - 0.0039 16.4 0.0 0.0084 15.3 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Kdo PF06293.9 KFP01927.1 - 0.1 11.6 0.0 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 KFP01927.1 - 3.2 7.0 15.2 4.8 6.4 10.5 1.3 1 0 0 1 1 1 0 Vta1 like MIP PF00230.15 KFP01928.1 - 5.4e-09 35.8 5.2 5.4e-09 35.8 3.6 1.8 1 1 0 2 2 2 1 Major intrinsic protein Voldacs PF03517.8 KFP01929.1 - 2.8e-34 117.8 1.2 3.5e-34 117.5 0.8 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling WHIM3 PF15614.1 KFP01930.1 - 5.1e-21 74.2 0.0 1.7e-20 72.5 0.0 2.0 1 1 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 PHD PF00628.24 KFP01930.1 - 5e-10 38.9 4.4 1.8e-09 37.1 3.1 2.1 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.1 KFP01930.1 - 7.1e-07 28.8 0.1 1.9e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KFP01930.1 - 1.8e-05 24.4 0.3 5e-05 23.0 0.2 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Prok-RING_1 PF14446.1 KFP01930.1 - 0.0059 16.3 1.2 0.016 14.9 0.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFP01930.1 - 0.061 12.6 0.2 0.061 12.6 0.1 2.3 2 0 0 2 2 2 0 PHD-finger Polyoma_lg_T_C PF06431.6 KFP01930.1 - 7 5.1 12.4 1.4 7.5 1.3 2.8 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus DUF498 PF04430.9 KFP01931.1 - 9.2e-23 79.9 0.0 1e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) HEAT PF02985.17 KFP01932.1 - 5.5e-26 88.2 5.3 0.00074 19.3 0.0 8.7 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 KFP01932.1 - 6.2e-21 74.4 3.5 8.2e-07 29.2 0.1 5.8 2 2 2 5 5 5 4 HEAT repeats Adaptin_N PF01602.15 KFP01932.1 - 4.6e-11 41.7 3.8 0.00025 19.5 0.1 3.3 2 1 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.2 KFP01932.1 - 2.6e-09 37.1 2.9 9.4e-06 25.5 0.3 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KFP01932.1 - 5.4e-08 33.1 2.5 0.00016 21.9 0.1 4.5 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFP01932.1 - 2.9e-07 30.7 7.9 0.12 12.8 0.3 6.8 7 1 1 8 8 8 2 HEAT-like repeat CLASP_N PF12348.3 KFP01932.1 - 1.2e-05 24.8 0.7 2.2 7.5 0.1 4.3 2 2 3 5 5 5 3 CLASP N terminal Cohesin_HEAT PF12765.2 KFP01932.1 - 6.6e-05 22.7 0.0 0.41 10.6 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF445 PF04286.7 KFP01932.1 - 0.002 17.7 2.6 0.18 11.3 0.1 2.8 2 1 0 3 3 3 2 Protein of unknown function (DUF445) Cnd3 PF12719.2 KFP01932.1 - 0.0022 17.0 1.2 0.67 8.8 0.0 3.0 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain API5 PF05918.6 KFP01932.1 - 0.051 12.0 0.1 0.21 10.0 0.0 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) HEAT_PBS PF03130.11 KFP01932.1 - 0.099 13.1 0.6 34 5.3 0.0 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat BTB_2 PF02214.17 KFP01933.1 - 1.4e-18 66.9 0.0 2.2e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain INT_SG_DDX_CT_C PF15300.1 KFP01933.1 - 0.15 11.5 0.1 0.6 9.6 0.0 2.1 2 1 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Spot_14 PF07084.7 KFP01934.1 - 1.9e-22 79.8 0.1 3.8e-22 78.8 0.1 1.5 1 1 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Spot_14 PF07084.7 KFP01935.1 - 3.6e-24 85.4 0.1 4.7e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 NDUF_C2 PF06374.6 KFP01936.1 - 1.4e-23 83.1 0.2 1.5e-23 83.0 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Alg6_Alg8 PF03155.10 KFP01937.1 - 2.8e-163 544.1 31.5 3.2e-163 543.9 21.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family BTB_2 PF02214.17 KFP01938.1 - 9.6e-22 77.0 0.0 1.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PH PF00169.24 KFP01939.1 - 6.9e-16 58.3 3.2 5.5e-15 55.4 0.1 3.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 KFP01939.1 - 5e-07 29.9 1.2 5.5e-06 26.5 0.8 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFP01939.1 - 0.078 12.8 0.3 0.26 11.1 0.2 1.9 1 1 0 1 1 1 0 PH domain tRNA-synt_2 PF00152.15 KFP01940.1 - 1.4e-76 257.4 0.0 1.7e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFP01940.1 - 1.8e-10 40.5 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFP01940.1 - 0.00088 18.5 1.4 0.81 8.8 0.4 2.7 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) Ten_N PF06484.7 KFP01941.1 - 1.2e-32 113.4 11.1 1.8e-32 112.8 7.7 1.3 1 0 0 1 1 1 1 Teneurin Intracellular Region Tox-GHH PF15636.1 KFP01941.1 - 1.1e-31 108.2 0.8 2.1e-31 107.3 0.6 1.5 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin EGF_2 PF07974.8 KFP01941.1 - 9.1e-19 67.3 156.7 0.00062 19.8 9.5 9.6 9 0 0 9 9 9 8 EGF-like domain NHL PF01436.16 KFP01941.1 - 2.8e-13 49.0 2.8 0.0026 17.6 0.0 7.1 6 0 0 6 6 6 3 NHL repeat RHS_repeat PF05593.9 KFP01941.1 - 2e-09 37.3 30.5 0.017 15.2 0.0 9.4 8 1 2 10 10 10 5 RHS Repeat hEGF PF12661.2 KFP01941.1 - 0.00012 21.9 77.4 0.025 14.6 2.5 9.3 8 0 0 8 8 8 6 Human growth factor-like EGF RHS PF03527.9 KFP01941.1 - 0.00038 20.1 0.0 0.088 12.5 0.0 2.9 2 0 0 2 2 2 1 RHS protein CarboxypepD_reg PF13620.1 KFP01941.1 - 0.0041 17.1 1.6 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Ten_N PF06484.7 KFP01942.1 - 1.1e-34 120.2 7.5 1.2e-34 120.0 5.2 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region Yae1_N PF09811.4 KFP01944.1 - 4.3e-15 54.9 50.0 3.8e+02 0.7 0.1 5.1 1 1 1 2 2 2 0 Essential protein Yae1, N terminal HEAT_2 PF13646.1 KFP01945.1 - 1.8e-05 24.9 0.1 0.00059 20.0 0.0 1.5 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 KFP01945.1 - 0.0059 16.5 0.7 0.25 11.5 0.0 3.0 3 0 0 3 3 3 1 HEAT repeat SH2 PF00017.19 KFP01946.1 - 3.6e-17 61.9 0.0 5.5e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Nucleos_tra2_C PF07662.8 KFP01947.1 - 6.5e-72 241.3 7.1 1.5e-71 240.1 4.9 1.7 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KFP01947.1 - 1.5e-19 70.0 3.7 1.5e-19 70.0 2.6 3.6 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KFP01947.1 - 1.1e-07 31.6 11.0 1.1e-07 31.6 7.6 3.6 3 2 0 3 3 3 1 Nucleoside recognition Alpha_kinase PF02816.13 KFP01948.1 - 6e-36 123.8 0.0 6.9e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_C14 PF00656.17 KFP01949.1 - 1.1e-20 74.4 0.0 1.6e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 Caspase domain DUF4254 PF14063.1 KFP01949.1 - 0.071 12.7 0.4 0.55 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) Peptidase_S24 PF00717.18 KFP01950.1 - 2e-10 40.1 0.1 3.8e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Bombesin PF02044.12 KFP01951.1 - 0.0093 15.3 5.4 0.015 14.7 3.7 1.4 1 0 0 1 1 1 1 Bombesin-like peptide DuoxA PF10204.4 KFP01952.1 - 7.2e-105 350.0 7.0 8.1e-105 349.8 4.9 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor BRI3BP PF14965.1 KFP01952.1 - 2.8 7.2 18.3 0.064 12.6 1.7 2.5 3 0 0 3 3 3 0 Negative regulator of p53/TP53 DUF4191 PF13829.1 KFP01952.1 - 5.9 5.9 9.5 1.8 7.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DuoxA PF10204.4 KFP01953.1 - 6.2e-111 369.9 9.7 7.2e-111 369.7 6.7 1.0 1 0 0 1 1 1 1 Dual oxidase maturation factor COPI_assoc PF08507.5 KFP01953.1 - 4.5 6.9 14.6 0.52 9.9 3.0 3.2 2 2 0 2 2 2 0 COPI associated protein An_peroxidase PF03098.10 KFP01954.1 - 1.8e-138 462.2 0.0 2.5e-138 461.7 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase NAD_binding_6 PF08030.7 KFP01954.1 - 3e-31 108.4 0.1 9.6e-31 106.7 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFP01954.1 - 4.6e-19 68.2 0.0 3.2e-17 62.2 0.0 2.6 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 KFP01954.1 - 7.1e-17 61.6 15.9 2.9e-16 59.7 11.0 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.27 KFP01954.1 - 3.1e-14 51.0 6.3 1.5e-06 27.0 0.6 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFP01954.1 - 8.3e-11 41.8 7.0 1e-05 25.5 1.1 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP01954.1 - 2.5e-09 36.6 8.3 0.00013 21.5 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP01954.1 - 2.5e-09 36.2 6.0 0.00087 18.9 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFP01954.1 - 6.3e-08 31.6 3.1 0.0061 15.8 0.3 3.0 2 0 0 2 2 2 2 EF hand NAD_binding_1 PF00175.16 KFP01954.1 - 4.9e-06 27.0 0.6 0.021 15.3 0.0 3.7 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFP01954.1 - 0.0027 17.8 0.0 0.0084 16.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain ADH_zinc_N PF00107.21 KFP01955.1 - 9e-26 89.9 0.5 1.6e-25 89.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KFP01955.1 - 0.0061 16.1 0.5 0.0091 15.5 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.7 KFP01955.1 - 0.037 13.7 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF281 PF03436.8 KFP01955.1 - 0.046 13.7 0.4 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF281) ADH_zinc_N_2 PF13602.1 KFP01955.1 - 0.074 13.9 0.0 0.14 13.0 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RRM_1 PF00076.17 KFP01956.1 - 3.9e-12 45.6 0.0 6.1e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP01956.1 - 1.4e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP01956.1 - 0.00012 21.9 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 KFP01957.1 - 3.6e-50 165.3 83.2 7.9e-07 29.0 0.8 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP01957.1 - 1.7e-35 119.5 73.1 3e-09 36.7 0.9 12.0 12 0 0 12 12 12 8 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP01957.1 - 2.1e-29 99.6 70.6 0.00028 20.9 0.8 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP01957.1 - 2e-16 59.2 67.4 0.0002 21.1 0.0 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP01957.1 - 9.4e-13 47.9 56.0 0.0014 18.6 0.4 10.6 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFP01957.1 - 2.6e-05 23.8 8.2 0.0001 22.0 0.7 8.2 4 3 4 8 8 8 3 BED zinc finger GAGA PF09237.6 KFP01957.1 - 0.0062 16.1 19.2 2.1 8.0 0.1 5.7 3 1 2 5 5 5 3 GAGA factor zf-met PF12874.2 KFP01957.1 - 0.31 11.3 48.1 0.56 10.4 0.2 9.4 9 0 0 9 9 9 0 Zinc-finger of C2H2 type BolA PF01722.13 KFP01957.1 - 0.54 10.2 4.6 54 3.8 0.0 4.9 3 3 2 5 5 5 0 BolA-like protein BAH PF01426.13 KFP01958.1 - 2.3e-40 137.0 0.0 2.8e-23 81.9 0.0 2.4 2 0 0 2 2 2 2 BAH domain zf-CXXC PF02008.15 KFP01958.1 - 3.1e-15 55.7 21.5 8.7e-15 54.2 14.9 1.8 1 0 0 1 1 1 1 CXXC zinc finger domain DNMT1-RFD PF12047.3 KFP01958.1 - 0.042 13.5 0.0 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain KH_1 PF00013.24 KFP01959.1 - 2.4e-32 110.3 5.6 2.5e-16 59.0 0.4 2.7 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 KFP01959.1 - 3.3e-23 80.8 3.3 4.8e-11 42.0 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_2 PF07650.12 KFP01959.1 - 1.5e-08 34.0 3.7 2.4e-05 23.7 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 KFP01959.1 - 3.8e-07 29.6 1.4 0.0051 16.4 0.0 2.8 3 0 0 3 3 3 2 KH domain dUTPase PF00692.14 KFP01959.1 - 0.042 13.3 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 dUTPase KH_5 PF13184.1 KFP01959.1 - 0.11 12.3 0.8 1 9.2 0.1 2.4 2 0 0 2 2 2 0 NusA-like KH domain Sec3-PIP2_bind PF15277.1 KFP01961.1 - 4.5e-27 93.7 0.1 8.6e-27 92.8 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Synaptobrevin PF00957.16 KFP01961.1 - 6.8e-06 25.6 0.5 6.8e-06 25.6 0.4 1.8 2 0 0 2 2 2 1 Synaptobrevin Actin PF00022.14 KFP01962.1 - 2.6e-160 533.1 0.0 2.9e-160 533.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFP01962.1 - 0.13 12.7 0.0 0.39 11.1 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AAA_11 PF13086.1 KFP01963.1 - 6.3e-27 94.6 0.0 1.7e-26 93.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KFP01963.1 - 4.5e-26 91.4 0.0 8.2e-25 87.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFP01963.1 - 6.3e-08 32.2 0.0 2.2e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KFP01963.1 - 0.00061 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KFP01963.1 - 0.0019 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KFP01963.1 - 0.0069 15.9 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KFP01963.1 - 0.013 14.5 0.3 0.14 11.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KFP01963.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 KFP01963.1 - 0.067 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.24 KFP01963.1 - 0.099 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF755 PF05501.6 KFP01963.1 - 0.31 11.0 1.7 0.72 9.9 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RecA PF00154.16 KFP01963.1 - 0.38 9.7 0.0 0.66 8.9 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ATP_bind_4 PF01902.12 KFP01964.1 - 1.4e-44 152.1 0.0 2.8e-44 151.1 0.0 1.4 1 1 0 1 1 1 1 ATP-binding region TPD PF14811.1 KFP01965.1 - 2e-53 179.6 0.0 1.1e-52 177.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif AsiA PF09010.5 KFP01965.1 - 0.057 13.2 0.2 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Anti-Sigma Factor A Homeobox_KN PF05920.6 KFP01966.1 - 1.1e-20 73.0 0.6 2e-20 72.2 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFP01966.1 - 1.8e-08 33.8 0.5 3.4e-08 32.9 0.3 1.4 1 0 0 1 1 1 1 Homeobox domain Oxidored_q3 PF00499.15 KFP01967.1 - 1.7e-08 34.3 8.1 1.7e-08 34.3 5.6 1.5 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2065 PF09838.4 KFP01967.1 - 0.013 15.2 0.6 0.013 15.2 0.4 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) EI24 PF07264.6 KFP01967.1 - 0.32 10.3 9.4 0.42 9.9 6.5 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Yae1_N PF09811.4 KFP01968.1 - 2.7e-18 65.1 49.2 0.00013 21.3 5.9 5.1 1 1 2 3 3 3 3 Essential protein Yae1, N terminal DUF2465 PF10239.4 KFP01969.1 - 4.3e-131 436.8 0.2 5e-131 436.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RasGEF PF00617.14 KFP01970.1 - 3.9e-48 163.6 0.2 7.6e-48 162.7 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain C1_1 PF00130.17 KFP01970.1 - 1e-13 50.7 8.0 2.2e-13 49.7 5.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RasGEF_N PF00618.15 KFP01970.1 - 7.4e-11 42.0 1.0 7.4e-11 42.0 0.7 2.3 3 0 0 3 3 3 1 RasGEF N-terminal motif EF-hand_7 PF13499.1 KFP01970.1 - 8.2e-09 35.4 0.2 7.1e-06 26.0 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP01970.1 - 1.2e-05 24.7 0.0 7.3e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KFP01970.1 - 2.6e-05 23.1 2.9 3.3e-05 22.8 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 KFP01970.1 - 0.00027 20.1 1.4 0.001 18.3 0.0 2.6 3 0 0 3 3 3 1 EF hand ACDC PF14733.1 KFP01970.1 - 0.0027 17.8 1.7 0.0087 16.1 0.2 2.4 2 0 0 2 2 2 1 AP2-coincident C-terminal EF-hand_8 PF13833.1 KFP01970.1 - 0.024 14.2 1.1 0.11 12.0 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair RhoGAP PF00620.22 KFP01971.1 - 4e-31 107.6 0.2 8.1e-31 106.6 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain DAN PF03045.10 KFP01972.1 - 5.7e-43 145.2 8.6 7.5e-43 144.8 6.0 1.2 1 0 0 1 1 1 1 DAN domain Neurensin PF14927.1 KFP01972.1 - 0.052 12.9 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Neurensin DUF2602 PF10782.4 KFP01972.1 - 2 8.3 8.0 6.5 6.6 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2602) FH2 PF02181.18 KFP01973.1 - 2.3e-101 339.3 7.7 4.3e-101 338.4 5.3 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain SpoIIID PF12116.3 KFP01974.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein D Luteo_P1-P2 PF08467.5 KFP01975.1 - 0.069 11.9 0.6 0.12 11.1 0.4 1.3 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase ARL2_Bind_BART PF11527.3 KFP01976.1 - 1.4e-29 102.3 3.5 1.7e-29 102.0 2.4 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART MARVEL PF01284.18 KFP01977.1 - 3.4e-21 75.5 22.5 4e-21 75.3 15.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Claudin_3 PF06653.6 KFP01977.1 - 0.0073 16.0 8.9 0.011 15.4 6.2 1.3 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF3169 PF11368.3 KFP01977.1 - 0.11 11.7 3.6 0.15 11.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) IL8 PF00048.15 KFP01978.1 - 0.083 12.8 0.9 0.11 12.5 0.7 1.2 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like CLTH PF10607.4 KFP01980.1 - 4.3e-44 149.7 0.0 6.1e-44 149.2 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KFP01980.1 - 5.3e-26 91.1 0.2 1.1e-25 90.1 0.1 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KFP01980.1 - 2.8e-05 23.7 0.0 6.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 LisH SR-25 PF10500.4 KFP01980.1 - 0.8 9.1 21.2 1.2 8.5 14.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-T PF15511.1 KFP01981.1 - 4.8e-19 68.9 0.0 5.5e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KFP01981.1 - 6.2e-08 32.7 0.0 7.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFP01981.1 - 1e-05 25.5 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFP01981.1 - 0.00062 19.8 0.2 0.00079 19.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KFP01981.1 - 0.054 13.2 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated NTF2 PF02136.15 KFP01982.1 - 5e-33 113.9 0.0 5.6e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Fcf1 PF04900.7 KFP01982.1 - 0.068 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Fcf1 SnoaL_4 PF13577.1 KFP01982.1 - 0.081 12.8 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 KFP01982.1 - 0.098 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Pkinase PF00069.20 KFP01983.1 - 7e-68 228.5 0.0 8e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP01983.1 - 1.7e-31 109.2 0.0 2.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP01983.1 - 2.1e-05 23.6 0.0 4.4e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFP01983.1 - 0.00011 22.0 0.1 0.19 11.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP01983.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3895 PF13034.1 KFP01983.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Trypsin PF00089.21 KFP01984.1 - 6e-40 137.1 0.2 9.9e-40 136.4 0.2 1.3 1 1 0 1 1 1 1 Trypsin DUF316 PF03761.10 KFP01984.1 - 0.015 14.6 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF316) Peptidase_C37 PF05416.7 KFP01984.1 - 0.13 10.5 0.1 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Trypsin PF00089.21 KFP01985.1 - 0.031 13.8 0.1 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Trypsin 5HT_transporter PF03491.8 KFP01985.1 - 0.074 13.1 0.1 0.094 12.8 0.1 1.1 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Sec6 PF06046.8 KFP01986.1 - 4.7e-126 421.1 4.3 4.7e-126 421.1 3.0 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec6 Sec8_exocyst PF04048.9 KFP01986.1 - 0.012 15.2 1.6 0.012 15.2 1.1 2.9 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain E2F_TDP PF02319.15 KFP01987.1 - 1e-14 53.7 0.1 2.1e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain XhlA PF10779.4 KFP01987.1 - 0.45 10.4 6.7 0.78 9.6 4.7 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DUF3361 PF11841.3 KFP01988.1 - 3.9e-54 182.7 1.5 8e-54 181.6 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 KFP01988.1 - 4.7e-48 162.9 0.2 7.9e-48 162.2 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF1910 PF08928.5 KFP01988.1 - 0.0078 16.2 0.6 4.9 7.2 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1910) DUF1704 PF08014.6 KFP01989.1 - 1.2e-12 47.5 0.0 2e-12 46.8 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) LCAT PF02450.10 KFP01990.1 - 3.8e-121 404.7 1.0 4.4e-121 404.5 0.7 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 KFP01990.1 - 1.7e-05 24.7 0.0 3.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFP01990.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.8 KFP01990.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF915 PF06028.6 KFP01990.1 - 0.023 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) HAD_2 PF13419.1 KFP01990.1 - 0.025 14.8 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF900 PF05990.7 KFP01990.1 - 0.031 13.5 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1749 PF08538.5 KFP01990.1 - 0.044 12.6 0.0 0.084 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) UBA_3 PF09288.5 KFP01990.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Adaptin_N PF01602.15 KFP01991.1 - 9.5e-32 110.0 0.1 9.3e-26 90.2 0.0 2.0 2 0 0 2 2 2 2 Adaptin N terminal region PuR_N PF09182.5 KFP01991.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Ank_2 PF12796.2 KFP01992.1 - 6.3e-81 266.8 16.8 1.9e-23 82.6 0.3 4.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFP01992.1 - 1.7e-60 197.9 15.8 5.1e-09 35.4 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KFP01992.1 - 2.3e-55 184.0 11.5 1.4e-12 47.7 0.0 6.1 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP01992.1 - 8.4e-50 161.7 8.0 1.5e-05 24.7 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 KFP01992.1 - 2.2e-48 161.1 14.6 4e-09 36.4 0.1 9.0 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Arm PF00514.18 KFP01993.1 - 2e-31 106.7 0.2 5e-08 32.4 0.0 7.3 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 KFP01993.1 - 2e-07 30.3 1.8 0.0012 18.0 0.0 3.2 2 1 1 3 3 3 2 Armadillo-like HEAT_2 PF13646.1 KFP01993.1 - 2.7e-05 24.3 0.4 0.029 14.6 0.0 2.7 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.17 KFP01993.1 - 0.00095 19.0 0.1 6.6 7.0 0.0 3.8 4 0 0 4 4 4 2 HEAT repeat Atx10homo_assoc PF09759.4 KFP01993.1 - 0.012 15.3 0.1 0.5 10.1 0.0 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain zf-C3HC PF07967.8 KFP01994.1 - 1e-32 112.6 12.0 1.1e-32 112.6 1.9 3.1 3 0 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.5 KFP01994.1 - 2.6e-12 46.4 13.5 1.5e-08 34.3 1.2 3.3 3 0 0 3 3 3 2 Rsm1-like DUF1220 PF06758.8 KFP01994.1 - 0.66 9.8 6.5 0.075 12.8 0.5 2.5 3 0 0 3 3 3 0 Repeat of unknown function (DUF1220) UQ_con PF00179.21 KFP01995.1 - 1.1e-36 125.3 0.0 1.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nrf1_DNA-bind PF10491.4 KFP01996.1 - 3.5e-129 428.2 0.3 5.4e-129 427.6 0.2 1.3 1 0 0 1 1 1 1 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Nrf1_activ_bdg PF10492.4 KFP01996.1 - 7.8e-07 29.4 5.4 7.8e-07 29.4 3.8 6.1 3 2 3 6 6 6 1 Nrf1 activator activation site binding domain RNF111_N PF15303.1 KFP01996.1 - 0.021 14.3 0.6 0.056 12.9 0.4 1.7 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DUF3459 PF11941.3 KFP01996.1 - 0.023 14.8 1.2 0.095 12.8 0.8 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) DUF1639 PF07797.9 KFP01997.1 - 2.1 7.8 4.5 0.38 10.1 0.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1639) AdoHcyase PF05221.12 KFP01998.1 - 2.8e-30 105.1 0.0 4.8e-30 104.4 0.0 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase PT PF04886.7 KFP01999.1 - 7.1e-22 76.4 198.5 1.5e+04 -159.3 137.6 9.5 1 1 0 1 1 1 0 PT repeat Ank PF00023.25 KFP02001.1 - 2.9e-20 70.9 0.1 1.2e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFP02001.1 - 4.8e-18 65.2 0.0 1.5e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP02001.1 - 1.4e-16 60.5 0.0 1e-11 45.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02001.1 - 4.1e-14 51.2 0.1 1.2e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KFP02001.1 - 6.8e-13 48.3 1.2 7.3e-10 38.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.23 KFP02001.1 - 2.7e-12 45.8 1.4 5.1e-12 44.9 0.9 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP02001.1 - 3.7e-11 42.4 0.3 8.9e-11 41.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP02001.1 - 1.6e-07 30.7 0.0 2.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.18 KFP02001.1 - 0.00036 20.9 0.5 0.012 16.0 0.4 2.7 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain ATG16 PF08614.6 KFP02002.1 - 0.00084 19.2 3.3 0.00084 19.2 2.3 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) IncA PF04156.9 KFP02002.1 - 0.0033 17.0 8.3 0.0033 17.0 5.8 2.0 2 1 0 2 2 2 1 IncA protein Filament PF00038.16 KFP02002.1 - 0.012 15.0 8.4 0.026 14.0 5.8 1.4 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 KFP02002.1 - 0.013 14.1 8.6 0.027 13.1 5.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.7 KFP02002.1 - 0.031 14.6 9.5 0.031 14.6 6.6 2.9 2 1 1 3 3 3 0 SlyX TPR_MLP1_2 PF07926.7 KFP02002.1 - 0.045 13.4 10.1 0.099 12.3 7.0 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFP02002.1 - 0.22 10.6 1.1 0.57 9.3 0.8 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 KFP02002.1 - 0.27 10.7 9.5 0.83 9.1 5.5 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 KFP02002.1 - 0.29 10.4 6.9 0.58 9.4 4.8 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2730 PF10805.3 KFP02002.1 - 0.4 10.4 6.3 0.77 9.5 2.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF3450 PF11932.3 KFP02002.1 - 0.42 9.8 10.2 0.19 10.9 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Scaffolding_pro PF11418.3 KFP02002.1 - 0.63 10.4 5.2 0.62 10.4 2.4 1.8 2 0 0 2 2 2 0 Phi29 scaffolding protein Adeno_PIX PF03955.9 KFP02002.1 - 0.92 10.0 3.8 0.78 10.2 1.1 2.1 2 1 0 2 2 1 0 Adenovirus hexon-associated protein (IX) TMF_DNA_bd PF12329.3 KFP02002.1 - 1.5 8.6 15.8 3.7 7.4 0.6 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KFP02002.1 - 1.6 9.1 11.0 1.5 9.1 4.4 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 KFP02002.1 - 2 8.1 16.0 5.7 6.6 8.4 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.6 KFP02002.1 - 2.8 7.8 8.2 4.7 7.0 2.7 2.7 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 KFP02002.1 - 2.9 8.1 10.2 10 6.4 5.7 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.7 KFP02002.1 - 3 7.8 5.7 10 6.2 0.1 3.5 4 0 0 4 4 2 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 KFP02002.1 - 3.6 7.9 14.3 15 6.0 9.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3287 PF11690.3 KFP02002.1 - 5.1 7.2 8.5 1.2 9.2 2.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF2458 PF10454.4 KFP02002.1 - 6 6.7 11.9 2.8 7.8 5.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) FA_desaturase PF00487.19 KFP02003.1 - 2e-24 86.4 13.3 2e-24 86.4 9.2 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.5 KFP02003.1 - 0.00097 18.3 0.1 0.0019 17.3 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) AAA PF00004.24 KFP02004.1 - 4.9e-95 314.7 0.0 7.4e-49 165.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFP02004.1 - 1.1e-13 50.8 0.0 6.5e-06 25.3 0.0 3.0 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFP02004.1 - 2.4e-13 50.3 0.4 0.027 14.6 0.0 5.5 3 2 2 5 5 5 3 AAA domain AAA_16 PF13191.1 KFP02004.1 - 4.7e-13 49.5 5.2 7.9e-06 25.9 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.9 KFP02004.1 - 1.1e-12 48.1 0.0 5.2e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KFP02004.1 - 1.1e-10 42.4 0.0 0.0015 19.3 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KFP02004.1 - 4.1e-10 39.6 0.0 0.001 18.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 KFP02004.1 - 4.8e-10 39.3 2.0 0.00017 21.3 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KFP02004.1 - 2.6e-09 36.4 0.1 6.6e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 KFP02004.1 - 7.5e-09 34.7 0.0 0.0033 16.2 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KFP02004.1 - 1.4e-08 34.3 1.7 0.0059 16.3 0.2 3.2 2 1 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 KFP02004.1 - 2e-08 34.2 0.0 0.0034 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KFP02004.1 - 7.6e-08 31.7 0.3 0.0041 16.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFP02004.1 - 1.8e-07 30.7 5.5 0.16 11.3 0.1 4.3 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.12 KFP02004.1 - 3.9e-07 29.6 0.1 0.027 13.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 KFP02004.1 - 5.3e-07 29.7 0.0 0.057 13.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KFP02004.1 - 6e-07 29.6 0.0 0.046 13.9 0.0 2.9 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 KFP02004.1 - 1.3e-06 28.7 0.1 0.085 13.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KFP02004.1 - 1.5e-06 27.8 0.0 0.031 13.7 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 KFP02004.1 - 2.1e-06 27.4 0.8 0.041 13.5 0.0 3.5 3 1 1 4 4 4 2 NACHT domain AAA_3 PF07726.6 KFP02004.1 - 7.5e-06 25.5 0.0 0.049 13.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KFP02004.1 - 2e-05 23.8 2.3 0.55 9.3 0.0 3.9 3 1 1 4 4 4 2 KaiC ABC_tran PF00005.22 KFP02004.1 - 2.6e-05 24.5 0.0 0.34 11.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 KFP02004.1 - 3e-05 24.0 0.6 0.09 12.8 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 KFP02004.1 - 3.9e-05 23.1 0.0 0.41 10.0 0.0 3.5 2 1 1 3 3 3 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 KFP02004.1 - 0.00024 21.0 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 2 Cytidylate kinase-like family NB-ARC PF00931.17 KFP02004.1 - 0.00026 19.9 0.0 0.44 9.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain SKI PF01202.17 KFP02004.1 - 0.00065 19.5 0.5 0.48 10.2 0.0 3.5 4 0 0 4 4 3 1 Shikimate kinase PhoH PF02562.11 KFP02004.1 - 0.00087 18.5 0.0 0.85 8.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.4 KFP02004.1 - 0.00088 18.3 0.2 0.98 8.3 0.0 3.7 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KFP02004.1 - 0.0015 18.1 0.1 0.67 9.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.10 KFP02004.1 - 0.0016 17.2 0.0 0.36 9.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 KFP02004.1 - 0.0017 18.1 0.0 9.1 5.9 0.0 4.1 2 2 1 3 3 3 0 Archaeal ATPase NTPase_1 PF03266.10 KFP02004.1 - 0.0029 17.3 0.2 4.4 6.9 0.0 3.5 2 2 1 3 3 3 0 NTPase ATP-synt_ab PF00006.20 KFP02004.1 - 0.0035 16.8 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 KFP02004.1 - 0.0041 16.7 0.2 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 KFP02004.1 - 0.0051 15.7 0.0 0.31 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KFP02004.1 - 0.0051 16.3 0.0 2.3 7.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.12 KFP02004.1 - 0.0055 15.6 0.0 2.2 7.0 0.0 2.6 2 1 0 2 2 2 1 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 KFP02004.1 - 0.019 14.8 0.1 8.9 6.2 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 KFP02004.1 - 0.033 13.7 0.0 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 KFP02004.1 - 0.054 13.3 0.5 19 5.0 0.0 3.2 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit DAP3 PF10236.4 KFP02004.1 - 0.078 11.8 0.3 4.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Cornichon PF03311.9 KFP02005.1 - 1.6e-46 157.6 8.4 1.8e-46 157.4 5.8 1.0 1 0 0 1 1 1 1 Cornichon protein PsbT PF01405.12 KFP02005.1 - 0.015 14.8 2.9 0.015 14.8 2.0 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre T protein DUF2650 PF10853.3 KFP02005.1 - 0.054 12.9 0.4 0.054 12.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) DUF2976 PF11190.3 KFP02005.1 - 0.24 10.9 3.2 4.5 6.8 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) WD40 PF00400.27 KFP02006.1 - 1.4e-41 138.8 3.9 8.9e-13 47.5 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KFP02006.1 - 2.4e-05 24.1 0.0 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 KFP02006.1 - 0.081 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain REC114-like PF15165.1 KFP02008.1 - 1.5e-88 296.6 3.6 2.8e-62 210.6 0.7 2.0 1 1 1 2 2 2 2 Meiotic recombination protein REC114-like Tryp_alpha_amyl PF00234.17 KFP02008.1 - 0.018 15.2 6.7 0.027 14.6 4.6 1.3 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family I-set PF07679.11 KFP02009.1 - 3.9e-16 58.6 0.2 5e-12 45.5 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP02009.1 - 5.8e-12 45.5 0.6 8.8e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP02009.1 - 2.9e-06 27.6 5.3 0.0012 19.3 0.5 2.6 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP02009.1 - 1.3e-05 25.0 2.0 0.11 12.4 0.2 3.1 2 2 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 KFP02009.1 - 0.00059 19.9 3.1 0.0037 17.3 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin domain TMEM154 PF15102.1 KFP02009.1 - 0.062 13.0 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family C1-set PF07654.10 KFP02010.1 - 4.7e-11 42.5 2.1 2.3e-10 40.3 0.3 2.5 2 1 0 2 2 2 1 Immunoglobulin C1-set domain Ig_2 PF13895.1 KFP02010.1 - 6.5e-11 42.2 0.3 6.9e-05 22.8 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP02010.1 - 2.1e-09 37.1 0.2 0.00048 19.9 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP02010.1 - 4.3e-09 36.7 0.7 0.00031 21.1 0.2 3.1 2 2 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFP02010.1 - 8.4e-08 32.0 0.8 1.7e-06 27.8 0.1 2.8 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFP02010.1 - 1.3e-07 31.4 0.1 6e-06 26.1 0.0 2.8 1 1 0 2 2 2 1 Immunoglobulin V-set domain ig PF00047.20 KFP02010.1 - 3.6e-07 30.2 1.0 0.016 15.3 0.1 3.2 3 0 0 3 3 3 2 Immunoglobulin domain FAM163 PF15069.1 KFP02010.1 - 0.037 14.6 0.3 0.088 13.3 0.2 1.7 1 1 0 1 1 1 0 FAM163 family DUF4363 PF14276.1 KFP02010.1 - 0.038 13.6 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) EphA2_TM PF14575.1 KFP02010.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.9 KFP02010.1 - 0.094 12.4 0.1 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Marek_A PF02124.10 KFP02010.1 - 0.67 9.3 3.3 1.4 8.3 2.3 1.5 1 1 0 1 1 1 0 Marek's disease glycoprotein A Zona_pellucida PF00100.18 KFP02011.1 - 5.7e-49 166.9 0.0 6.5e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Lysyl_oxidase PF01186.12 KFP02012.1 - 1.7e-119 396.8 6.0 1.9e-119 396.7 4.1 1.0 1 0 0 1 1 1 1 Lysyl oxidase CARDB PF07705.6 KFP02012.1 - 0.0022 18.0 0.0 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 CARDB Integrin_alpha2 PF08441.7 KFP02013.1 - 5.4e-32 111.2 0.0 5.9e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Integrin alpha G-patch PF01585.18 KFP02014.1 - 2.1e-13 49.8 1.1 5.3e-13 48.5 0.7 1.7 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 KFP02014.1 - 1.7e-06 28.0 8.4 1.7e-06 28.0 5.8 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP02014.1 - 0.0016 18.5 1.8 0.0044 17.1 1.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.2 KFP02014.1 - 0.0019 18.0 0.2 0.016 15.0 0.2 2.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 KFP02014.1 - 0.017 15.2 2.1 0.038 14.0 1.5 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 KFP02014.1 - 0.042 13.5 4.8 0.11 12.2 3.3 1.6 1 0 0 1 1 1 0 DBF zinc finger Frizzled PF01534.12 KFP02015.1 - 1.1e-145 484.5 17.8 1.4e-145 484.1 12.3 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFP02015.1 - 2.5e-52 176.1 11.3 4.4e-35 120.5 2.6 2.4 2 0 0 2 2 2 2 Fz domain SEN1_N PF12726.2 KFP02016.1 - 0.054 11.5 0.0 0.054 11.5 0.0 1.0 1 0 0 1 1 1 0 SEN1 N terminal CLASP_N PF12348.3 KFP02016.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 CLASP N terminal Myosin_head PF00063.16 KFP02017.1 - 5.1e-198 659.4 6.2 2.4e-173 577.8 3.3 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.1 KFP02017.1 - 0.005 16.9 0.1 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFP02017.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 KFP02017.1 - 0.026 13.9 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 KFP02017.1 - 0.034 14.9 0.7 0.19 12.5 0.0 2.6 1 1 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.7 KFP02017.1 - 0.04 13.2 1.6 2.6 7.3 0.3 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.1 KFP02017.1 - 0.071 13.4 0.0 0.28 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 KFP02018.1 - 1.7e-46 158.5 0.0 2.5e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02018.1 - 7.1e-29 100.6 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP02019.1 - 3.6e-19 68.9 0.0 4.3e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02019.1 - 3.4e-06 26.3 0.0 4.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase HEXIM PF15313.1 KFP02020.1 - 1.3e-44 151.2 3.8 2.2e-44 150.5 2.6 1.3 1 0 0 1 1 1 1 Hexamethylene bis-acetamide-inducible protein DUF972 PF06156.8 KFP02020.1 - 0.33 11.3 5.7 1.3 9.4 3.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) SPX PF03105.14 KFP02020.1 - 2.4 7.8 8.0 1.5 8.4 4.1 1.7 1 1 1 2 2 2 0 SPX domain CAGE1 PF15066.1 KFP02020.1 - 3.1 6.1 10.2 0.22 9.9 3.7 1.5 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family NMT_C PF02799.10 KFP02021.1 - 7.8e-85 283.0 0.0 1.1e-84 282.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KFP02021.1 - 6.8e-83 276.1 0.0 1e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_3 PF13302.1 KFP02021.1 - 0.0091 16.1 0.0 0.29 11.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFP02021.1 - 0.023 14.5 0.0 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFP02021.1 - 0.031 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFP02021.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CoaE PF01121.15 KFP02022.1 - 8.5e-61 204.4 0.0 1e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 KFP02022.1 - 4.6e-05 23.7 0.1 0.00018 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFP02022.1 - 0.00017 22.4 0.0 0.00033 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFP02022.1 - 0.00079 19.3 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP02022.1 - 0.0012 18.8 0.2 0.0019 18.2 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 KFP02022.1 - 0.12 12.3 0.1 0.33 10.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain Sec10 PF07393.6 KFP02022.1 - 0.13 10.4 0.1 0.19 9.8 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 C1q PF00386.16 KFP02023.1 - 1.4e-17 63.9 0.0 1.5e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 KFP02023.1 - 0.078 12.5 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Kinesin PF00225.18 KFP02024.1 - 1.9e-109 365.4 0.0 2.6e-109 364.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain V-set PF07686.12 KFP02025.1 - 3e-14 52.8 0.0 7.4e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP02025.1 - 1.3e-06 28.4 0.0 0.032 14.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP02025.1 - 1.4e-05 24.8 0.0 0.11 12.3 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFP02025.1 - 3.5e-05 23.8 0.0 0.41 10.7 0.0 3.0 2 2 0 2 2 2 2 Immunoglobulin domain Receptor_2B4 PF11465.3 KFP02025.1 - 0.031 14.1 0.0 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 RPAP3_C PF13877.1 KFP02026.1 - 2.3e-20 72.3 0.0 3.7e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 GTP_EFTU PF00009.22 KFP02027.1 - 4.7e-43 146.8 0.0 7e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFP02027.1 - 1.1e-26 92.6 0.0 2.5e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KFP02027.1 - 1.1e-21 76.4 0.0 3e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFP02027.1 - 1.8e-11 43.9 0.0 5.2e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KFP02027.1 - 2e-08 33.9 0.0 5.3e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 KFP02027.1 - 4.1e-05 24.0 0.0 8.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 KFP02027.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin Nop14 PF04147.7 KFP02027.1 - 6.5 4.5 5.9 9.5 3.9 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family Connexin PF00029.14 KFP02028.1 - 5.9e-51 171.0 0.5 1e-50 170.2 0.4 1.3 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFP02028.1 - 9.3e-23 79.8 1.0 9.3e-23 79.8 0.7 2.0 2 0 0 2 2 2 1 Gap junction channel protein cysteine-rich domain Reprolysin PF01421.14 KFP02029.1 - 5.2e-60 202.4 0.0 9.8e-60 201.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Disintegrin PF00200.18 KFP02029.1 - 1.2e-18 67.0 28.6 1.2e-18 67.0 19.8 2.7 2 0 0 2 2 2 1 Disintegrin Reprolysin_3 PF13582.1 KFP02029.1 - 7.2e-10 39.4 0.1 1.3e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR PF08516.7 KFP02029.1 - 1.1e-09 38.3 1.3 1.1e-09 38.3 0.9 3.8 3 1 0 4 4 4 1 ADAM cysteine-rich Reprolysin_5 PF13688.1 KFP02029.1 - 4.2e-09 36.6 0.4 9.6e-09 35.4 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFP02029.1 - 6.3e-06 26.3 0.2 2.6e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP02029.1 - 3.4e-05 23.4 0.0 6.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFP02029.1 - 0.00024 21.1 10.5 0.00024 21.1 7.3 5.9 6 1 0 6 6 6 1 EGF-like domain hEGF PF12661.2 KFP02029.1 - 0.028 14.4 0.7 0.028 14.4 0.5 4.9 5 0 0 5 5 5 0 Human growth factor-like EGF DicB PF05358.6 KFP02030.1 - 0.015 14.7 2.3 0.07 12.6 0.1 2.7 3 0 0 3 3 3 0 DicB protein DUF1539 PF07560.6 KFP02030.1 - 0.45 10.4 4.1 0.23 11.3 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF4582 PF15189.1 KFP02031.1 - 4.5e-79 263.6 0.0 4e-78 260.5 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4582) NTPase_1 PF03266.10 KFP02031.1 - 0.0077 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 NTPase ALIX_LYPXL_bnd PF13949.1 KFP02031.1 - 0.018 14.0 0.0 0.048 12.6 0.0 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV AAA PF00004.24 KFP02032.1 - 6.2e-58 194.6 0.0 1.2e-41 142.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KFP02032.1 - 1.1e-14 54.0 0.0 2.1e-13 50.0 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 KFP02032.1 - 1.4e-13 50.2 4.2 1.5e-13 50.1 0.1 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KFP02032.1 - 1.1e-09 38.5 0.2 0.0022 18.1 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFP02032.1 - 1.5e-09 38.7 0.0 0.0019 18.9 0.0 2.9 2 1 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KFP02032.1 - 3.7e-09 36.5 0.0 0.0031 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KFP02032.1 - 4.5e-08 33.1 0.0 6e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KFP02032.1 - 4.7e-08 33.1 0.1 0.011 15.9 0.0 3.3 4 0 0 4 4 2 2 RNA helicase RuvB_N PF05496.7 KFP02032.1 - 1.1e-07 31.1 0.0 0.0099 14.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFP02032.1 - 5.7e-07 29.3 0.0 0.00073 19.2 0.1 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KFP02032.1 - 1e-06 28.6 0.0 0.053 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KFP02032.1 - 2.8e-06 26.3 0.0 0.038 12.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KFP02032.1 - 5.7e-06 26.0 0.1 0.1 12.3 0.0 3.0 3 0 0 3 3 3 2 Part of AAA domain AAA_16 PF13191.1 KFP02032.1 - 6.1e-06 26.3 0.0 0.0051 16.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFP02032.1 - 7.7e-06 26.2 0.0 0.019 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KFP02032.1 - 9.6e-06 24.8 0.1 0.0035 16.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFP02032.1 - 2.8e-05 23.3 0.0 0.27 10.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 KFP02032.1 - 9.5e-05 22.1 0.0 0.63 9.6 0.0 3.6 3 1 0 3 3 3 2 NACHT domain Arch_ATPase PF01637.13 KFP02032.1 - 0.00015 21.5 0.1 0.24 11.0 0.0 3.4 2 2 1 3 3 3 1 Archaeal ATPase KTI12 PF08433.5 KFP02032.1 - 0.00047 19.4 0.2 1 8.4 0.0 3.2 3 0 0 3 3 3 2 Chromatin associated protein KTI12 KaiC PF06745.8 KFP02032.1 - 0.00086 18.4 0.1 0.016 14.3 0.0 2.8 2 1 1 3 3 3 1 KaiC AAA_25 PF13481.1 KFP02032.1 - 0.0012 18.3 0.1 1 8.6 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.1 KFP02032.1 - 0.0012 18.8 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KFP02032.1 - 0.0018 17.9 0.0 0.28 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KFP02032.1 - 0.002 17.5 0.0 0.15 11.5 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_tran PF00005.22 KFP02032.1 - 0.0028 17.9 0.0 0.014 15.7 0.0 2.2 2 0 0 2 2 1 1 ABC transporter UPF0079 PF02367.12 KFP02032.1 - 0.003 17.1 0.1 0.44 10.1 0.0 2.9 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 KFP02032.1 - 0.0032 16.9 0.0 1.3 8.4 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 KFP02032.1 - 0.0093 15.5 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KFP02032.1 - 0.013 14.3 0.0 1.8 7.3 0.0 2.6 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFP02032.1 - 0.019 13.8 0.0 0.44 9.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.6 KFP02032.1 - 0.031 13.7 0.0 0.69 9.3 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E NTPase_1 PF03266.10 KFP02032.1 - 0.069 12.8 0.0 19 4.9 0.0 3.1 2 1 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.1 KFP02032.1 - 0.072 13.1 0.1 12 5.9 0.0 3.3 3 1 0 3 3 2 0 Sigma-54 interaction domain CPT PF07931.7 KFP02032.1 - 0.072 12.7 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein wnt PF00110.14 KFP02033.1 - 1.1e-120 402.5 15.7 1.2e-120 402.4 10.9 1.0 1 0 0 1 1 1 1 wnt family V-SNARE_C PF12352.3 KFP02034.1 - 2.6e-18 65.8 1.4 2.6e-18 65.8 1.0 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFP02034.1 - 3.7e-06 26.5 0.8 5.7e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 Sec20 V-SNARE PF05008.10 KFP02034.1 - 0.0014 18.7 1.3 0.0036 17.4 0.9 1.8 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus Ran-binding PF05508.6 KFP02034.1 - 0.0022 16.9 1.8 0.0032 16.4 1.3 1.2 1 0 0 1 1 1 1 RanGTP-binding protein SLX9 PF15341.1 KFP02034.1 - 0.032 14.6 1.1 0.042 14.2 0.8 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Fmp27_WPPW PF10359.4 KFP02034.1 - 0.35 9.2 7.6 0.59 8.4 3.6 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.7 KFP02034.1 - 0.51 10.1 2.9 0.5 10.1 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.1 KFP02034.1 - 0.82 9.6 4.6 1.7 8.6 0.2 2.3 1 1 1 2 2 2 0 FlxA-like protein IncA PF04156.9 KFP02034.1 - 1.9 8.0 8.9 4.3 6.8 6.1 1.8 1 1 0 1 1 1 0 IncA protein zf-U11-48K PF05253.7 KFP02035.1 - 2e-19 68.9 14.0 7.7e-10 38.2 0.7 2.3 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger Peptidase_C48 PF02902.14 KFP02036.1 - 6.7e-34 117.4 1.7 7.2e-20 71.5 0.2 2.6 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Myosin_head PF00063.16 KFP02037.1 - 1.1e-219 730.9 0.3 1.1e-219 730.9 0.2 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.22 KFP02037.1 - 0.0021 17.5 1.4 0.0057 16.1 1.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myosin_N PF02736.14 KFP02037.1 - 0.038 13.6 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 KFP02037.1 - 0.54 10.3 0.0 0.54 10.3 0.0 2.8 4 0 0 4 4 4 0 AAA domain SPX PF03105.14 KFP02037.1 - 9 5.9 26.2 36 3.9 18.1 2.1 1 1 0 1 1 1 0 SPX domain SEA PF01390.15 KFP02038.1 - 3.5e-42 142.4 1.8 4e-20 71.4 0.1 2.5 2 0 0 2 2 2 2 SEA domain EGF PF00008.22 KFP02038.1 - 0.23 11.4 8.0 3.9 7.5 0.3 2.4 2 0 0 2 2 2 0 EGF-like domain EGF_3 PF12947.2 KFP02038.1 - 3 7.8 8.1 0.17 11.8 1.1 2.1 2 0 0 2 2 2 0 EGF domain Yae1_N PF09811.4 KFP02039.1 - 2e-09 36.8 27.7 3.5 7.2 19.2 3.0 1 1 0 1 1 1 1 Essential protein Yae1, N terminal 7tm_1 PF00001.16 KFP02040.1 - 8.8e-90 300.3 13.0 1.1e-89 300.0 9.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02040.1 - 1.7e-10 40.5 11.9 1.5e-09 37.4 8.2 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP02040.1 - 5.9e-06 25.5 5.1 5.9e-06 25.5 3.5 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx ABC2_membrane_2 PF12679.2 KFP02040.1 - 0.61 8.8 14.6 1.1 7.9 0.1 2.7 1 1 2 3 3 3 0 ABC-2 family transporter protein Mei4 PF13971.1 KFP02042.1 - 3e-82 276.5 12.0 3.5e-82 276.3 8.3 1.0 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 WD40 PF00400.27 KFP02043.1 - 2.3e-47 157.2 18.5 8.5e-08 31.7 0.0 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Bromodomain PF00439.20 KFP02043.1 - 2e-37 126.9 1.3 1.2e-17 63.5 0.0 3.2 3 0 0 3 3 3 2 Bromodomain HMG14_17 PF01101.13 KFP02044.1 - 5.8e-23 81.3 22.1 6.5e-23 81.2 15.3 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 TT_ORF2 PF02957.10 KFP02044.1 - 0.1 13.2 9.9 0.12 13.0 6.9 1.0 1 0 0 1 1 1 0 TT viral ORF2 DUF2477 PF10631.4 KFP02044.1 - 0.49 10.6 2.8 0.52 10.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Lebercilin PF15619.1 KFP02045.1 - 2.4e-71 239.1 53.3 2.4e-71 239.1 36.9 2.2 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease CSTF_C PF14304.1 KFP02045.1 - 0.033 13.4 1.0 0.12 11.6 0.7 2.0 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal IncA PF04156.9 KFP02045.1 - 0.25 10.9 58.9 0.53 9.8 16.8 3.3 2 1 1 3 3 3 0 IncA protein Sec2p PF06428.6 KFP02045.1 - 0.37 10.6 33.7 0.58 10.0 1.5 4.6 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p FUSC PF04632.7 KFP02045.1 - 5.4 5.3 9.7 8.2 4.7 6.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ELO PF01151.13 KFP02046.1 - 6.5e-66 222.1 25.0 7.7e-66 221.9 17.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pkinase PF00069.20 KFP02047.1 - 1.5e-62 211.1 0.9 2.7e-62 210.2 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02047.1 - 1.8e-33 115.7 0.1 3.1e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP02047.1 - 4.3e-09 35.7 3.1 5.5e-07 28.8 0.0 3.5 4 0 0 4 4 4 1 Kinase-like APH PF01636.18 KFP02047.1 - 7.9e-06 25.7 0.0 0.21 11.2 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP02047.1 - 0.00023 20.2 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP02047.1 - 0.0011 18.3 2.9 0.014 14.7 0.1 2.4 1 1 1 2 2 2 1 RIO1 family Tubulin PF00091.20 KFP02047.1 - 0.0036 17.1 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Mad3_BUB1_I PF08311.7 KFP02047.1 - 0.0088 15.8 0.1 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Transket_pyr PF02779.19 KFP02048.1 - 2.6e-43 147.5 0.0 3.4e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFP02048.1 - 8e-36 122.7 0.0 2.4e-35 121.1 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Yae1_N PF09811.4 KFP02049.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF1693 PF07984.7 KFP02050.1 - 2.2e-123 411.4 1.7 2.6e-123 411.2 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) BTB PF00651.26 KFP02051.1 - 3.8e-30 104.1 7.0 2.4e-15 56.4 1.0 3.1 2 1 1 3 3 3 2 BTB/POZ domain RCC1 PF00415.13 KFP02051.1 - 6.6e-30 103.0 17.8 5.6e-11 42.4 1.3 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 KFP02051.1 - 5e-14 52.0 0.0 1.3e-06 28.3 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP02051.1 - 1e-09 37.6 0.0 8.9e-05 22.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFP02051.1 - 3.3e-09 36.9 0.0 1.1e-05 25.8 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFP02051.1 - 5.5e-09 36.2 0.0 2.4e-08 34.2 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.1 KFP02051.1 - 4.4e-08 32.5 12.8 0.00037 20.0 0.0 5.4 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 KFP02051.1 - 3.6e-05 23.6 0.0 0.72 10.2 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Rab15_effector PF15208.1 KFP02051.1 - 0.027 13.9 0.3 0.38 10.1 0.0 2.4 2 0 0 2 2 2 0 Rab15 effector DUF2632 PF10943.3 KFP02051.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) HECT_2 PF09814.4 KFP02053.1 - 8.2e-79 264.8 1.0 1e-78 264.5 0.7 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Tnp_zf-ribbon_2 PF13842.1 KFP02053.1 - 0.014 15.7 2.6 5.9 7.3 0.5 2.8 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Dopey_N PF04118.9 KFP02054.1 - 2e-106 355.2 0.1 1e-105 352.9 0.0 2.2 2 0 0 2 2 2 1 Dopey, N-terminal PGM_PMM_I PF02878.11 KFP02055.1 - 2.9e-19 68.9 0.0 2.5e-08 33.4 0.0 3.4 2 2 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFP02055.1 - 4.1e-12 46.3 0.1 2.5e-11 43.8 0.0 2.4 2 1 1 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFP02055.1 - 2e-10 40.5 1.9 2.7e-10 40.1 0.1 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KFP02055.1 - 0.0003 20.8 0.5 0.0012 18.9 0.3 2.1 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF1115 PF06544.7 KFP02056.1 - 7e-27 93.6 0.1 1.1e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.17 KFP02056.1 - 1e-13 51.1 0.0 2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF950 PF06106.6 KFP02056.1 - 0.0053 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Staphylococcus protein of unknown function (DUF950) THDPS_N_2 PF14805.1 KFP02056.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal malic PF00390.14 KFP02057.1 - 2.6e-80 268.2 0.0 4.2e-80 267.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.10 KFP02057.1 - 2.1e-73 246.9 0.7 7.8e-73 245.1 0.5 1.8 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain Trypsin PF00089.21 KFP02058.1 - 4.1e-11 42.8 0.0 4.1e-09 36.3 0.0 2.6 2 1 0 2 2 2 2 Trypsin Trypsin_2 PF13365.1 KFP02058.1 - 3.7e-06 26.9 0.0 1.1e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.10 KFP02058.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF316) ANTH PF07651.11 KFP02059.1 - 8.4e-84 280.5 0.4 1e-83 280.3 0.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KFP02059.1 - 1.1e-14 54.3 0.0 1.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 KFP02059.1 - 0.045 13.3 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 VHS domain Ripply PF14998.1 KFP02060.1 - 1.6e-29 101.8 0.2 2e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Transcription Regulator Cyt-b5 PF00173.23 KFP02061.1 - 5.3e-24 83.8 0.0 1.3e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 KFP02061.1 - 6.8e-17 61.4 0.0 2.3e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFP02061.1 - 1.1e-15 58.1 0.0 3.1e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CS PF04969.11 KFP02061.1 - 1.4e-10 41.5 0.3 3.9e-10 40.1 0.2 1.8 1 0 0 1 1 1 1 CS domain NAD_binding_6 PF08030.7 KFP02061.1 - 3.1e-05 23.9 0.0 0.0019 18.1 0.0 2.5 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF1863 PF08937.6 KFP02061.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) MRAP PF15183.1 KFP02062.1 - 6.7e-34 115.3 0.1 9.8e-34 114.8 0.1 1.2 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family DUF3735 PF12537.3 KFP02063.1 - 0.55 10.3 0.0 0.55 10.3 0.0 5.5 6 1 0 6 6 6 0 Protein of unknown function (DUF3735) T-box PF00907.17 KFP02064.1 - 6.9e-86 286.4 0.0 7.7e-86 286.2 0.0 1.0 1 0 0 1 1 1 1 T-box Pkinase PF00069.20 KFP02065.1 - 7.6e-72 241.5 0.0 9.5e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02065.1 - 2e-42 145.0 0.0 2.8e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP02065.1 - 2e-10 40.0 0.0 2.1e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP02065.1 - 4.2e-05 22.7 0.1 7.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP02065.1 - 0.00034 20.0 0.5 0.00077 18.8 0.4 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 KFP02065.1 - 0.0019 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 KFP02065.1 - 0.047 12.9 1.9 0.42 9.7 1.3 2.1 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KFP02065.1 - 0.11 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 KFP02065.1 - 0.16 11.0 0.8 0.42 9.7 0.3 1.8 1 1 1 2 2 2 0 Ecdysteroid kinase 5_nucleotid_C PF02872.13 KFP02066.1 - 2.4e-37 128.3 0.0 4.5e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KFP02066.1 - 2.8e-05 23.5 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PXA PF02194.10 KFP02067.1 - 8.3e-43 146.1 0.3 8.3e-43 146.1 0.2 1.7 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KFP02067.1 - 2.2e-25 88.9 0.0 8.8e-25 87.0 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KFP02067.1 - 2.3e-20 72.4 1.1 2.3e-20 72.4 0.7 2.7 3 0 0 3 3 3 1 PX domain RGS PF00615.14 KFP02067.1 - 1.6e-12 47.5 3.1 2.4e-12 46.9 0.7 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF2151 PF10221.4 KFP02067.1 - 7.3 4.6 6.1 5.8 4.9 0.0 2.8 3 0 0 3 3 3 0 Cell cycle and development regulator RRM_1 PF00076.17 KFP02068.1 - 1.6e-45 152.5 2.2 3e-16 58.7 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02068.1 - 8.8e-38 128.1 0.1 6.8e-14 51.6 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP02068.1 - 1.7e-20 72.5 0.2 9.3e-07 28.6 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFP02068.1 - 1.5e-05 24.6 1.3 0.05 13.3 0.2 3.6 2 2 1 3 3 3 2 Limkain b1 Calcipressin PF04847.7 KFP02068.1 - 0.012 15.1 0.1 0.3 10.6 0.1 2.7 2 1 1 3 3 3 0 Calcipressin Yae1_N PF09811.4 KFP02069.1 - 1.2e-18 66.2 57.7 1.5e+04 -18.4 40.0 5.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal 7tm_1 PF00001.16 KFP02070.1 - 4.1e-80 268.6 10.4 5.4e-80 268.2 7.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02070.1 - 4.7e-07 29.2 12.1 8.9e-07 28.3 8.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP02070.1 - 7.6e-06 25.2 14.5 1.6e-05 24.1 10.0 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx CytochromB561_N PF09786.4 KFP02070.1 - 0.12 10.7 3.7 3 6.2 1.6 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal Hormone_6 PF00236.13 KFP02071.1 - 1.5e-54 181.8 8.9 1.8e-54 181.5 6.2 1.1 1 0 0 1 1 1 1 Glycoprotein hormone PDGF PF00341.12 KFP02071.1 - 0.064 13.3 9.6 0.12 12.4 6.6 1.5 1 1 0 1 1 1 0 PDGF/VEGF domain zf-C2H2_4 PF13894.1 KFP02072.1 - 5.2e-09 35.8 98.7 0.071 13.4 0.2 16.4 16 0 0 16 16 16 10 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP02072.1 - 9.7e-09 35.0 108.7 0.0098 16.1 1.9 15.7 16 0 0 16 16 16 10 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFP02072.1 - 4.4 7.3 51.8 1.1 9.2 0.2 10.5 11 0 0 11 11 11 0 C2H2-type zinc finger Connexin PF00029.14 KFP02073.1 - 6.5e-47 158.0 0.8 9.4e-47 157.5 0.5 1.2 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFP02073.1 - 4.7e-29 99.9 2.5 1.2e-28 98.6 1.7 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Yae1_N PF09811.4 KFP02074.1 - 1.5e-15 56.4 51.0 1.5e+04 -12.2 35.4 5.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF3508 PF12018.3 KFP02075.1 - 5.1e-91 304.5 6.6 5.1e-91 304.5 4.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3508) ATP-synt_D PF01813.12 KFP02075.1 - 0.019 14.5 0.7 1.9 7.9 0.2 2.9 2 1 1 3 3 3 0 ATP synthase subunit D TraC_F_IV PF11130.3 KFP02075.1 - 0.029 13.7 0.0 0.13 11.6 0.0 2.1 2 1 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer YHS PF04945.8 KFP02075.1 - 0.097 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 YHS domain Nuc_sug_transp PF04142.10 KFP02076.1 - 1.5e-93 312.4 17.3 1.5e-93 312.4 12.0 1.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 KFP02076.1 - 4.7e-09 35.5 17.7 4.7e-09 35.5 12.3 1.9 1 1 0 2 2 2 1 UAA transporter family EmrE PF13536.1 KFP02076.1 - 0.00024 21.2 2.6 0.00024 21.2 1.8 3.5 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 KFP02076.1 - 0.00041 20.3 1.2 0.00041 20.3 0.8 3.0 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 KFP02076.1 - 0.00051 19.7 29.9 0.0083 15.7 4.9 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF307 PF03733.8 KFP02076.1 - 0.068 13.6 0.4 0.068 13.6 0.3 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF307) DUF3963 PF13124.1 KFP02076.1 - 0.47 10.2 0.0 0.47 10.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) tRNA-synt_1d PF00750.14 KFP02077.1 - 8.5e-73 245.1 0.9 1.1e-72 244.8 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KFP02077.1 - 5.8e-21 74.6 2.6 6e-21 74.5 0.2 2.3 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KFP02077.1 - 0.0063 17.0 0.1 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.6 KFP02077.1 - 0.03 12.9 1.2 0.69 8.5 0.2 2.3 1 1 1 2 2 2 0 tRNA synthetases class I (M) ORC3_N PF07034.6 KFP02078.1 - 2.7e-124 414.4 5.0 2.7e-124 414.4 3.5 1.6 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus TAFH PF07531.9 KFP02078.1 - 0.0092 15.6 5.8 3 7.5 0.1 4.6 5 0 0 5 5 5 2 NHR1 homology to TAF DUF885 PF05960.6 KFP02079.1 - 0.0089 15.2 0.1 0.0093 15.1 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Nnf1 PF03980.9 KFP02079.1 - 0.037 14.0 1.0 5.8 6.9 0.2 2.2 2 0 0 2 2 2 0 Nnf1 HMG_box PF00505.14 KFP02079.1 - 0.15 12.3 2.0 0.2 11.9 0.0 2.0 2 1 0 2 2 2 0 HMG (high mobility group) box Gelsolin PF00626.17 KFP02080.1 - 0.00028 20.5 0.1 0.002 17.7 0.0 2.2 3 0 0 3 3 3 1 Gelsolin repeat Sec23_helical PF04815.10 KFP02080.1 - 0.00086 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 helical domain SERTA PF06031.8 KFP02080.1 - 0.11 11.8 0.1 0.58 9.4 0.0 2.1 2 1 0 2 2 2 0 SERTA motif DUF930 PF06059.7 KFP02081.1 - 0.00071 19.7 0.1 0.001 19.2 0.0 1.3 1 1 0 1 1 1 1 Domain of Unknown Function (DUF930) Rifin_STEVOR PF02009.11 KFP02081.1 - 0.026 14.1 0.5 0.028 14.0 0.3 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF4519 PF15012.1 KFP02081.1 - 0.039 13.8 0.7 0.069 13.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Peptidase_M56 PF05569.6 KFP02081.1 - 0.047 12.6 0.1 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Shisa PF13908.1 KFP02081.1 - 0.073 13.2 1.0 0.097 12.8 0.7 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator UPF0233 PF06781.7 KFP02081.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF912 PF06024.7 KFP02081.1 - 0.13 12.2 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pox_A14 PF05767.7 KFP02081.1 - 3.1 7.8 5.6 4 7.4 2.3 2.0 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.16 KFP02082.1 - 2e-50 171.3 17.6 3e-50 170.7 12.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02082.1 - 1.6e-12 47.1 17.0 2.4e-12 46.5 11.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP02082.1 - 2.5e-05 23.5 11.3 2.5e-05 23.5 7.9 1.9 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx Flavi_NS4B PF01349.12 KFP02082.1 - 0.0025 16.7 0.1 0.0049 15.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus non-structural protein NS4B DUF3671 PF12420.3 KFP02082.1 - 3.9 7.4 14.0 0.24 11.4 3.2 2.7 3 0 0 3 3 3 0 Protein of unknown function mRNA_cap_enzyme PF01331.14 KFP02083.1 - 1.7e-70 236.6 0.2 2.9e-70 235.8 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KFP02083.1 - 5.7e-31 106.9 0.1 1e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.15 KFP02083.1 - 1.2e-10 41.1 0.0 2.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.16 KFP02083.1 - 1.8e-06 27.4 0.0 0.00027 20.3 0.0 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Y_phosphatase PF00102.22 KFP02083.1 - 7.2e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KFP02083.1 - 0.033 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KFP02083.1 - 0.059 13.6 0.0 0.25 11.5 0.0 1.8 1 1 1 2 2 2 0 Tyrosine phosphatase family PNRC PF15365.1 KFP02084.1 - 1.5e-20 72.9 0.9 1.5e-20 72.9 0.6 1.9 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator Amelogenin PF02948.10 KFP02084.1 - 0.14 12.7 4.8 0.2 12.2 3.3 1.3 1 1 0 1 1 1 0 Amelogenin M20_dimer PF07687.9 KFP02085.1 - 1.2e-09 37.8 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KFP02085.1 - 0.062 12.8 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Neur_chan_LBD PF02931.18 KFP02086.1 - 5.1e-55 185.9 0.7 7.2e-55 185.4 0.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP02086.1 - 5e-41 141.1 10.8 7.9e-36 124.1 1.8 2.8 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 KFP02087.1 - 4e-41 141.4 5.5 2.1e-35 122.7 2.0 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP02087.1 - 3.6e-35 121.0 0.9 1.7e-34 118.8 0.6 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Gtr1_RagA PF04670.7 KFP02088.1 - 1.1e-73 247.1 0.8 1.6e-73 246.6 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KFP02088.1 - 7.7e-07 28.5 0.0 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFP02088.1 - 1.2e-05 24.5 0.1 2.8e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFP02088.1 - 3e-05 24.4 0.0 0.00016 22.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 KFP02088.1 - 0.004 16.5 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KFP02088.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KFP02088.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KFP02089.1 - 1e-63 211.6 26.3 1.8e-19 69.8 0.6 4.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFP02089.1 - 5.2e-52 171.1 24.3 3.1e-11 42.5 0.4 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KFP02089.1 - 3.5e-41 138.8 20.2 7.2e-10 39.1 0.2 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP02089.1 - 2.9e-40 135.3 28.8 6.3e-11 42.1 0.3 6.5 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02089.1 - 9.1e-39 127.6 13.0 6.5e-07 28.9 0.1 8.6 8 0 0 8 8 8 7 Ankyrin repeat XhlA PF10779.4 KFP02089.1 - 1.1 9.2 7.2 0.58 10.1 1.8 2.8 2 0 0 2 2 2 0 Haemolysin XhlA Complex1_LYR PF05347.10 KFP02090.1 - 1.6e-19 69.4 0.8 2.1e-19 69.0 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFP02090.1 - 2.4e-17 62.8 0.7 2.9e-17 62.6 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFP02090.1 - 2.4e-05 24.7 0.8 3e-05 24.4 0.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ETC_C1_NDUFA5 PF04716.9 KFP02090.1 - 0.0035 16.8 0.3 0.059 12.9 0.0 2.1 2 0 0 2 2 2 1 ETC complex I subunit conserved region AAA_5 PF07728.9 KFP02091.1 - 2.8e-124 409.4 0.0 6.1e-25 87.5 0.0 9.1 7 1 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA PF00004.24 KFP02091.1 - 2.6e-25 89.1 0.3 0.00035 20.7 0.0 7.2 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFP02091.1 - 4.4e-23 82.2 7.3 7.2e-06 26.1 0.1 8.3 7 0 0 7 7 7 5 AAA ATPase domain AAA_3 PF07726.6 KFP02091.1 - 2.6e-22 78.8 0.0 2.1e-07 30.5 0.0 7.2 7 0 0 7 7 7 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFP02091.1 - 4.5e-20 71.8 0.0 0.00073 19.4 0.0 7.7 6 1 1 7 7 7 4 AAA domain AAA_22 PF13401.1 KFP02091.1 - 3.2e-17 62.9 4.8 0.052 13.6 0.0 8.2 7 1 0 7 7 6 4 AAA domain AAA_17 PF13207.1 KFP02091.1 - 2.6e-16 60.5 0.1 0.12 13.1 0.0 7.3 6 0 0 6 6 5 4 AAA domain Sigma54_activ_2 PF14532.1 KFP02091.1 - 1e-15 57.9 0.1 0.0011 19.0 0.0 6.9 6 0 0 6 6 6 3 Sigma-54 interaction domain ABC_tran PF00005.22 KFP02091.1 - 2.4e-14 53.7 6.8 0.006 16.8 0.0 7.7 7 0 0 7 7 6 3 ABC transporter Miro PF08477.8 KFP02091.1 - 3.7e-14 53.2 0.1 1.4 9.4 0.0 7.5 6 0 0 6 6 6 3 Miro-like protein UPF0079 PF02367.12 KFP02091.1 - 1.3e-13 50.6 4.8 0.011 15.3 0.1 6.8 7 0 0 7 7 6 3 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 KFP02091.1 - 2.1e-13 50.1 1.4 0.41 10.0 0.0 7.1 7 0 0 7 7 7 3 Sigma-54 interaction domain AAA_33 PF13671.1 KFP02091.1 - 1.6e-11 44.2 0.0 0.037 13.8 0.0 7.3 7 2 0 7 7 6 2 AAA domain AAA_19 PF13245.1 KFP02091.1 - 1e-10 41.1 8.6 0.17 11.6 0.0 6.5 6 0 0 6 6 6 4 Part of AAA domain AAA_25 PF13481.1 KFP02091.1 - 1.1e-09 38.0 1.8 1.4 8.3 0.0 5.8 6 0 0 6 6 5 3 AAA domain NACHT PF05729.7 KFP02091.1 - 3.6e-09 36.5 4.5 1.7 8.3 0.0 7.1 6 0 0 6 6 6 2 NACHT domain AAA_18 PF13238.1 KFP02091.1 - 4.3e-09 36.7 24.3 0.2 11.9 0.0 8.6 10 0 0 10 10 6 4 AAA domain AAA_29 PF13555.1 KFP02091.1 - 7.7e-09 34.9 0.3 1.4 8.4 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KFP02091.1 - 3.4e-08 32.9 8.0 3.1 6.9 0.0 8.0 6 2 0 7 7 7 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFP02091.1 - 4.7e-08 33.1 0.4 4.6 7.4 0.0 6.6 6 0 0 6 6 6 1 RNA helicase MobB PF03205.9 KFP02091.1 - 7.5e-08 32.1 2.2 0.37 10.4 0.0 6.2 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFP02091.1 - 1.4e-07 31.0 4.5 0.18 11.3 0.0 5.9 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KFP02091.1 - 1.5e-06 27.7 2.5 2.5 7.4 0.0 5.3 5 0 0 5 5 5 2 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KFP02091.1 - 1e-05 25.5 13.7 1.7 8.5 0.0 7.8 8 0 0 8 8 7 1 AAA domain MMR_HSR1 PF01926.18 KFP02091.1 - 8.4e-05 22.4 0.0 32 4.5 0.0 6.5 6 0 0 6 6 6 0 50S ribosome-binding GTPase RuvB_N PF05496.7 KFP02091.1 - 0.00029 19.9 7.1 5 6.1 0.0 5.9 7 0 0 7 7 6 0 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 KFP02091.1 - 0.0011 18.5 0.0 1.2 8.6 0.0 3.9 4 0 0 4 4 3 1 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 KFP02091.1 - 0.0055 15.8 0.6 1.2 8.1 0.0 3.7 3 0 0 3 3 3 1 KaiC PhoH PF02562.11 KFP02091.1 - 0.065 12.4 6.4 60 2.7 0.0 5.5 6 0 0 6 6 5 0 PhoH-like protein Ras PF00071.17 KFP02091.1 - 0.85 8.9 6.5 19 4.6 0.0 4.7 5 0 0 5 5 5 0 Ras family NTPase_1 PF03266.10 KFP02091.1 - 7.8 6.1 8.2 43 3.7 0.0 4.7 6 0 0 6 6 5 0 NTPase Connexin PF00029.14 KFP02092.1 - 1.2e-49 166.8 0.3 2.3e-49 165.9 0.2 1.4 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFP02092.1 - 3e-24 84.5 0.7 7.1e-24 83.4 0.5 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain IncA PF04156.9 KFP02092.1 - 0.052 13.1 0.5 0.086 12.4 0.3 1.3 1 0 0 1 1 1 0 IncA protein Herpes_UL25 PF01499.11 KFP02092.1 - 0.15 10.3 1.0 0.2 9.9 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family BTB PF00651.26 KFP02093.1 - 4.1e-28 97.5 0.2 7e-28 96.8 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain bZIP_Maf PF03131.12 KFP02093.1 - 3.1e-13 49.8 2.2 7.1e-13 48.6 1.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 KFP02093.1 - 1e-09 38.1 6.9 2.1e-09 37.2 4.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP02093.1 - 1.7e-05 24.5 8.0 3.4e-05 23.5 5.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Pkinase_Tyr PF07714.12 KFP02094.1 - 4.3e-61 206.2 0.0 7.2e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP02094.1 - 3.2e-57 193.6 0.0 6.9e-57 192.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KFP02094.1 - 0.0019 17.9 0.3 0.0056 16.4 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Mnd1 PF03962.10 KFP02094.1 - 0.02 14.5 12.5 0.092 12.3 7.6 2.3 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 KFP02094.1 - 8.5 5.9 10.5 5.4 6.5 4.9 2.3 3 0 0 3 3 3 0 IncA protein DUF3432 PF11914.3 KFP02095.1 - 2.7e-35 120.3 38.3 2.7e-35 120.3 26.5 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3432) DUF3446 PF11928.3 KFP02095.1 - 8.2e-30 102.8 15.7 8.2e-30 102.8 10.9 4.4 4 1 1 5 5 2 1 Domain of unknown function (DUF3446) zf-H2C2_2 PF13465.1 KFP02095.1 - 2.1e-18 65.6 19.3 7e-09 35.5 0.5 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFP02095.1 - 1.9e-15 56.1 15.6 1.4e-05 25.1 0.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP02095.1 - 1.1e-13 50.4 13.7 0.0003 20.9 0.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFP02095.1 - 0.0018 17.8 8.8 0.1 12.2 0.3 3.4 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFP02095.1 - 0.0024 17.9 4.0 4.7 7.4 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding RRN7 PF11781.3 KFP02095.1 - 0.017 14.6 7.1 0.11 11.9 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_6 PF13912.1 KFP02095.1 - 0.021 14.7 7.6 1.7 8.6 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 KFP02095.1 - 0.021 14.5 9.2 0.048 13.4 2.7 2.7 1 1 2 3 3 3 0 BED zinc finger zf-met PF12874.2 KFP02095.1 - 0.19 11.9 5.5 17 5.7 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type C1_2 PF03107.11 KFP02095.1 - 0.28 11.3 2.4 8.3 6.6 0.1 2.5 2 0 0 2 2 2 0 C1 domain zf-UBR PF02207.15 KFP02095.1 - 0.42 10.3 3.7 0.7 9.6 2.5 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TB2_DP1_HVA22 PF03134.14 KFP02096.1 - 1.4e-31 108.0 10.3 1.9e-31 107.6 7.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family JmjC PF02373.17 KFP02097.1 - 1.3e-15 57.6 0.0 3e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KFP02097.1 - 0.099 12.1 0.1 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Cupin domain zf-UDP PF14569.1 KFP02097.1 - 0.58 9.9 6.7 1.1 9.0 0.8 2.7 2 0 0 2 2 2 0 Zinc-binding RING-finger 2-Hacid_dh_C PF02826.14 KFP02098.1 - 1.5e-56 190.3 0.0 2.1e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFP02098.1 - 1.4e-26 92.4 0.0 1.8e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFP02098.1 - 6.1e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFP02098.1 - 0.059 13.8 0.0 0.66 10.4 0.0 2.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 KFP02098.1 - 0.059 13.6 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain GDNF PF02351.11 KFP02099.1 - 3e-34 117.3 44.1 6.5e-18 65.0 6.4 3.2 3 0 0 3 3 3 3 GDNF/GAS1 domain APC8 PF04049.8 KFP02100.1 - 1.3e-29 102.7 2.2 1.3e-29 102.7 1.6 2.9 3 1 0 4 4 4 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KFP02100.1 - 7.3e-28 95.0 36.7 5.5e-06 25.7 0.1 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFP02100.1 - 1.3e-25 87.2 37.6 0.00044 19.9 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 KFP02100.1 - 2.9e-20 71.6 31.6 5.3e-08 32.3 0.6 7.8 5 1 3 8 8 8 6 TPR repeat TPR_8 PF13181.1 KFP02100.1 - 3.9e-17 60.6 31.2 0.00027 20.5 0.0 10.1 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFP02100.1 - 9.9e-16 56.8 16.2 0.0087 16.6 0.0 9.7 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP02100.1 - 1.9e-13 50.1 32.1 0.0016 18.3 0.9 8.7 4 2 7 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.1 KFP02100.1 - 2.4e-12 45.6 23.3 0.023 14.4 0.2 9.1 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFP02100.1 - 8.7e-10 39.0 19.4 0.00026 21.5 0.0 7.8 5 3 2 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP02100.1 - 9.4e-10 38.6 20.5 0.008 16.4 0.1 7.2 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP02100.1 - 7.8e-09 35.0 17.4 0.044 14.0 0.0 7.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFP02100.1 - 1.4e-06 28.3 33.7 1.2 9.7 0.0 10.6 12 0 0 12 12 11 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP02100.1 - 9.2e-06 25.7 39.3 0.014 15.5 0.7 6.7 4 2 4 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 DUF772 PF05598.6 KFP02100.1 - 0.0002 21.2 0.1 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 Transposase domain (DUF772) TPR_10 PF13374.1 KFP02100.1 - 0.00024 20.9 10.0 2.8 8.0 0.0 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP02100.1 - 0.0059 16.4 7.2 0.069 13.0 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 KFP02100.1 - 0.14 12.2 1.7 11 6.2 0.0 4.4 5 0 0 5 5 5 0 PPR repeat Pox_A_type_inc PF04508.7 KFP02101.1 - 0.059 13.1 0.0 0.059 13.1 0.0 9.9 12 1 0 12 12 12 0 Viral A-type inclusion protein repeat Amidohydro_1 PF01979.15 KFP02102.1 - 7.8e-37 127.6 0.0 1.1e-36 127.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFP02102.1 - 1.7e-15 57.8 0.0 2.4e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFP02102.1 - 5e-11 42.2 3.3 5.9e-11 42.0 0.6 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KFP02102.1 - 5.2e-07 29.2 0.1 0.0079 15.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 KFP02102.1 - 6.4e-06 25.9 0.1 2.6e-05 23.9 0.0 2.0 3 0 0 3 3 3 1 Amidohydrolase Pkinase PF00069.20 KFP02103.1 - 1.8e-62 210.8 0.0 1.8e-62 210.8 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02103.1 - 2.5e-39 134.8 0.1 3.3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP02103.1 - 2.6e-13 49.5 0.0 3.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP02103.1 - 0.0029 17.3 0.4 0.0048 16.6 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.27 KFP02104.1 - 1.5e-15 56.3 1.8 0.54 10.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat RRM_5 PF13893.1 KFP02105.1 - 8.8e-17 60.7 0.0 6.9e-09 35.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02105.1 - 2.3e-11 43.4 0.1 1.6e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFP02105.1 - 3.2e-11 42.8 0.0 1.4e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 KFP02105.1 - 4.5e-10 39.0 0.6 8.6e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KFP02105.1 - 1.7e-05 24.4 0.6 0.081 12.6 0.0 3.1 2 2 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KFP02105.1 - 3.9e-05 23.2 1.0 7e-05 22.4 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 KFP02105.1 - 0.0058 16.7 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 PWI domain DUF342 PF03961.8 KFP02105.1 - 0.15 10.4 10.9 0.26 9.6 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ly49 PF08391.5 KFP02105.1 - 1.1 9.4 5.7 5.5 7.1 3.9 2.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region tRNA-synt_1 PF00133.17 KFP02106.1 - 1.1e-37 129.3 0.0 2e-24 85.5 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFP02106.1 - 8.1e-21 74.1 0.0 2.6e-10 39.5 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFP02106.1 - 3.4e-17 62.6 0.0 9.3e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFP02106.1 - 1.1e-06 28.0 0.0 2.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KFP02106.1 - 0.018 13.7 0.4 0.071 11.7 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF3650 PF12368.3 KFP02107.1 - 0.021 14.3 0.1 1.8 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DnaJ_CXXCXGXG PF00684.14 KFP02107.1 - 0.2 11.7 14.3 0.23 11.5 3.8 2.3 1 1 1 2 2 2 0 DnaJ central domain DZR PF12773.2 KFP02107.1 - 3 7.7 14.8 5.5 6.8 0.0 2.9 2 1 1 3 3 3 0 Double zinc ribbon BTB_2 PF02214.17 KFP02108.1 - 6.4e-16 58.3 0.0 1.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Yip1 PF04893.12 KFP02110.1 - 1.3e-09 37.7 16.7 1.8e-09 37.3 11.6 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2374 PF09574.5 KFP02110.1 - 0.016 14.8 1.1 0.045 13.3 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (Duf2374) GCR PF02155.10 KFP02111.1 - 1.6e-171 570.1 5.4 2e-171 569.7 3.8 1.1 1 0 0 1 1 1 1 Glucocorticoid receptor Hormone_recep PF00104.25 KFP02111.1 - 2e-30 105.4 4.5 3e-30 104.8 3.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP02111.1 - 9.7e-24 83.4 15.7 6.4e-23 80.7 10.9 2.2 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) RhoGAP PF00620.22 KFP02112.1 - 4.6e-41 139.9 1.3 1.4e-40 138.3 0.5 2.0 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.1 KFP02112.1 - 7.2e-11 41.5 0.0 1.4e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP02112.1 - 4.1e-08 32.4 0.0 8e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP02112.1 - 8.9e-06 25.1 0.0 1.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IMD PF08397.6 KFP02112.1 - 0.00095 18.5 5.2 0.0028 16.9 3.2 2.1 2 0 0 2 2 2 1 IRSp53/MIM homology domain FGF PF00167.13 KFP02113.1 - 4.1e-40 136.3 0.0 5e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFP02113.1 - 0.00083 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Fascin domain DUF2370 PF10176.4 KFP02115.1 - 3.6e-36 124.6 9.7 1.8e-26 92.9 0.1 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF2370) Herpes_UL56 PF04534.7 KFP02115.1 - 0.074 12.7 0.5 0.11 12.2 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein DUF872 PF05915.7 KFP02115.1 - 0.24 11.2 1.5 0.43 10.4 0.4 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) TMEM52 PF14979.1 KFP02115.1 - 8.8 6.2 6.3 4.6 7.1 0.4 2.4 2 1 0 2 2 2 0 Transmembrane 52 Glucosamine_iso PF01182.15 KFP02116.1 - 1.9e-13 50.5 0.0 3.5e-13 49.7 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RWD PF05773.17 KFP02117.1 - 3.2e-24 85.0 0.0 7.2e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KFP02117.1 - 2.5e-18 65.6 22.7 1.8e-12 46.9 4.5 4.9 4 1 1 5 5 5 3 IBR domain zf-RING_5 PF14634.1 KFP02117.1 - 0.00028 20.5 13.4 0.00028 20.5 9.3 5.0 4 1 1 5 5 5 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP02117.1 - 0.0067 16.2 12.0 0.0067 16.2 8.3 5.1 4 1 1 5 5 5 2 Ring finger domain zf-C3HC4_2 PF13923.1 KFP02117.1 - 0.02 14.9 13.5 0.02 14.9 9.4 5.5 6 0 0 6 6 6 0 Zinc finger, C3HC4 type (RING finger) HSP70 PF00012.15 KFP02118.1 - 5.8e-182 605.7 11.1 1.5e-174 581.2 0.0 3.1 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 KFP02118.1 - 1.5e-07 30.3 0.0 0.00034 19.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BP28CT PF08146.7 KFP02118.1 - 0.062 13.0 0.3 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 BP28CT (NUC211) domain Ndc1_Nup PF09531.5 KFP02118.1 - 0.87 7.9 2.6 1.5 7.1 1.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF853 PF05872.7 KFP02118.1 - 4.2 5.5 10.9 0.43 8.8 0.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) zf-CCHC_3 PF13917.1 KFP02119.1 - 1.4e-19 69.4 3.1 3e-19 68.4 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF605 PF04652.11 KFP02119.1 - 0.014 14.7 26.0 0.016 14.6 18.0 1.0 1 0 0 1 1 1 0 Vta1 like zf-CCHC PF00098.18 KFP02119.1 - 0.21 11.5 2.2 0.31 11.0 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle BUD22 PF09073.5 KFP02119.1 - 0.86 8.5 42.9 1 8.3 29.8 1.0 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.4 KFP02119.1 - 3.1 5.9 36.9 3.3 5.8 25.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 KFP02119.1 - 4.8 6.1 27.7 5.9 5.8 19.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain eIF3g PF12353.3 KFP02119.1 - 8.9 6.2 10.1 0.17 11.7 0.7 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G AF-4 PF05110.8 KFP02120.1 - 0 1616.3 130.2 0 1616.1 90.3 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein LEAP-2 PF07359.6 KFP02121.1 - 4.7e-26 90.2 1.5 5e-26 90.1 1.0 1.0 1 0 0 1 1 1 1 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.13 KFP02121.1 - 0.072 13.1 0.2 0.072 13.1 0.1 1.2 1 0 0 1 1 1 0 EB module UcrQ PF02939.11 KFP02122.1 - 8.6e-34 115.2 0.0 9.5e-34 115.0 0.0 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 KFP02122.1 - 0.028 14.5 0.0 0.036 14.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2741) TGF_beta PF00019.15 KFP02123.1 - 7.3e-24 84.0 0.2 1.4e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain ASD1 PF08688.5 KFP02124.1 - 1.2e-43 148.9 6.8 1.2e-43 148.9 4.7 1.6 1 1 0 1 1 1 1 Apx/Shroom domain ASD1 ASD2 PF08687.6 KFP02125.1 - 4.2e-65 219.7 15.1 4.6e-65 219.5 10.4 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 ResB PF05140.9 KFP02125.1 - 0.0099 14.4 0.1 0.016 13.7 0.1 1.2 1 0 0 1 1 1 1 ResB-like family DUF2721 PF11026.3 KFP02125.1 - 0.01 15.4 0.7 0.021 14.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Oxysterol_BP PF01237.13 KFP02125.1 - 0.025 13.0 0.9 0.027 12.9 0.7 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein COG2 PF06148.6 KFP02125.1 - 0.12 12.2 6.6 4.7 7.1 0.2 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Diacid_rec PF05651.8 KFP02125.1 - 0.16 11.3 0.4 0.26 10.7 0.2 1.4 1 1 0 1 1 1 0 Putative sugar diacid recognition AAA_23 PF13476.1 KFP02125.1 - 0.27 11.5 7.5 0.41 10.9 5.2 1.3 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 KFP02125.1 - 9.6 6.6 9.3 2.1 8.7 0.7 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Septin PF00735.13 KFP02126.1 - 2.1e-99 332.1 2.1 2.1e-99 332.1 1.4 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFP02126.1 - 8.4e-06 25.7 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP02126.1 - 0.00012 21.5 2.5 1.3 8.3 0.1 3.2 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFP02126.1 - 0.00021 20.4 0.1 0.0025 17.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFP02126.1 - 0.00042 20.3 0.7 0.0048 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFP02126.1 - 0.00092 19.3 0.7 0.0025 17.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFP02126.1 - 0.0024 18.1 1.5 0.019 15.2 0.0 2.5 2 1 0 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.13 KFP02126.1 - 0.003 17.0 3.3 0.056 12.9 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Ras PF00071.17 KFP02126.1 - 0.0035 16.7 0.5 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 KFP02126.1 - 0.0042 16.5 2.9 0.011 15.1 2.0 1.9 1 1 0 1 1 1 1 AAA-like domain IMD PF08397.6 KFP02126.1 - 0.015 14.6 12.5 0.028 13.7 8.7 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Miro PF08477.8 KFP02126.1 - 0.021 15.3 1.3 0.058 13.8 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 KFP02126.1 - 0.022 13.8 5.5 0.055 12.5 0.0 2.5 2 0 0 2 2 2 0 AIG1 family Exonuc_VII_L PF02601.10 KFP02126.1 - 0.022 13.9 10.2 0.038 13.1 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_11 PF13086.1 KFP02126.1 - 0.024 14.2 3.8 0.041 13.4 2.6 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFP02126.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 KFP02126.1 - 0.053 12.4 0.0 0.053 12.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 KFP02126.1 - 0.12 11.9 0.1 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 KFP02126.1 - 0.17 11.7 5.9 0.68 9.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_32 PF13654.1 KFP02126.1 - 0.21 10.2 14.8 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain FliT PF05400.8 KFP02126.1 - 0.25 11.7 9.5 0.61 10.5 6.6 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Dynamin_N PF00350.18 KFP02126.1 - 0.57 9.9 7.4 4.2 7.1 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Fzo_mitofusin PF04799.8 KFP02126.1 - 1.2 8.5 8.7 1.1 8.6 4.9 1.7 2 0 0 2 2 2 0 fzo-like conserved region DUF3287 PF11690.3 KFP02126.1 - 1.6 8.7 12.9 39 4.3 8.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) ATP_bind_1 PF03029.12 KFP02126.1 - 4.5 6.7 7.0 12 5.3 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IncA PF04156.9 KFP02126.1 - 5.6 6.5 11.0 12 5.4 7.7 1.6 1 0 0 1 1 1 0 IncA protein Kinesin PF00225.18 KFP02127.1 - 3.3e-107 358.0 0.0 3.3e-107 358.0 0.0 1.8 2 1 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 KFP02127.1 - 0.0042 17.2 3.0 1.1 9.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain Rad50_zn_hook PF04423.9 KFP02128.1 - 7.7e-14 50.8 0.1 7.7e-14 50.8 0.0 6.3 5 0 0 5 5 5 1 Rad50 zinc hook motif SbcCD_C PF13558.1 KFP02128.1 - 1.6e-12 47.2 0.1 6.4e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KFP02128.1 - 5.9e-12 45.2 7.8 6.3e-08 32.1 3.2 3.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFP02128.1 - 2e-11 44.6 46.1 2e-11 44.6 32.0 9.5 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 KFP02128.1 - 5.9e-11 42.8 8.1 3.3e-05 23.9 0.0 3.5 3 2 1 4 4 4 2 AAA domain AAA_13 PF13166.1 KFP02128.1 - 0.00012 20.6 129.8 0.017 13.6 0.0 8.1 3 1 2 7 7 7 5 AAA domain AAA_29 PF13555.1 KFP02128.1 - 0.0078 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KFP02128.1 - 0.15 11.8 0.1 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain IRF PF00605.12 KFP02129.1 - 2e-46 156.2 1.1 3.5e-46 155.5 0.8 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Sugar_tr PF00083.19 KFP02130.1 - 7.8e-25 87.3 23.9 9.8e-25 87.0 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP02130.1 - 4.2e-21 75.0 57.3 2e-19 69.5 23.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.17 KFP02131.1 - 4.3e-15 55.5 3.8 7.5e-15 54.7 2.6 1.4 1 0 0 1 1 1 1 LIM domain PDZ PF00595.19 KFP02131.1 - 1.5e-11 44.3 0.1 3.4e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP02131.1 - 0.00012 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain P4Ha_N PF08336.6 KFP02132.1 - 4.8e-43 146.1 2.5 4.9e-43 146.1 0.2 2.0 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 KFP02132.1 - 4.1e-12 46.2 0.0 8.8e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KFP02132.1 - 1.7e-07 31.6 0.1 5.5e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 KFP02133.1 - 3.6e-101 338.5 0.0 5.6e-101 337.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFP02133.1 - 0.16 12.9 0.0 0.45 11.5 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FNIP_M PF14637.1 KFP02135.1 - 2.4e-86 289.1 0.0 4.9e-86 288.1 0.0 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 KFP02135.1 - 4.7e-71 238.1 0.2 2.4e-70 235.7 0.1 2.2 2 0 0 2 2 2 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 KFP02135.1 - 2.4e-36 125.0 0.5 2.4e-36 125.0 0.3 2.6 4 0 0 4 4 4 1 Folliculin-interacting protein N-terminus RasGEF_N PF00618.15 KFP02136.1 - 1.8e-18 66.5 0.8 4.9e-18 65.1 0.6 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif cNMP_binding PF00027.24 KFP02136.1 - 6.4e-14 51.5 0.0 1.2e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RA PF00788.18 KFP02136.1 - 2.6e-12 47.0 0.0 7.7e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 KFP02136.1 - 3.5e-12 46.3 0.0 7.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP02136.1 - 5.6e-05 22.9 0.0 0.00017 21.3 0.0 1.8 2 0 0 2 2 2 1 PDZ domain I-set PF07679.11 KFP02137.1 - 5.8e-25 86.9 0.0 3.4e-15 55.6 0.0 3.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP02137.1 - 3.6e-20 71.8 0.0 5.7e-10 39.1 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP02137.1 - 1.3e-15 57.5 0.0 2.5e-10 40.7 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP02137.1 - 9.9e-12 44.8 0.0 1.2e-05 25.2 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP02137.1 - 2e-08 34.0 0.3 0.00035 20.4 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin V-set domain EF-hand_1 PF00036.27 KFP02137.1 - 2.5e-08 32.6 0.0 4.3e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 EF hand Kazal_2 PF07648.10 KFP02137.1 - 4.3e-08 32.9 2.9 1.2e-07 31.5 2.0 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP02137.1 - 2.1e-07 30.8 8.7 5.9e-07 29.4 6.0 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.1 KFP02137.1 - 2.3e-07 30.8 3.2 5.3e-07 29.6 2.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP02137.1 - 3.9e-07 29.1 0.0 0.0059 15.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP02137.1 - 1.5e-06 27.5 0.3 0.0096 15.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFP02137.1 - 0.00014 21.8 0.7 0.00028 20.9 0.5 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 KFP02137.1 - 0.0047 16.5 0.1 0.21 11.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair C2-set_2 PF08205.7 KFP02137.1 - 0.0048 16.7 0.0 0.099 12.5 0.0 2.6 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Cytochrom_D1 PF02239.11 KFP02137.1 - 0.006 14.9 0.3 0.029 12.6 0.1 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain LVIVD PF08309.6 KFP02137.1 - 0.092 11.7 0.3 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 LVIVD repeat EF-hand_4 PF12763.2 KFP02137.1 - 0.11 12.2 0.2 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Borrelia_REV PF03978.8 KFP02138.1 - 0.2 11.3 0.2 0.2 11.3 0.2 2.2 2 1 1 3 3 3 0 Borrelia burgdorferi REV protein Porin_3 PF01459.17 KFP02139.1 - 3.7e-76 256.0 2.6 4.2e-76 255.8 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin OMP_b-brl PF13505.1 KFP02139.1 - 0.26 11.2 10.0 0.093 12.6 3.1 2.2 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain CTNNB1_binding PF08347.6 KFP02140.1 - 7.7e-45 153.6 8.8 7.7e-45 153.6 6.1 2.3 2 1 1 3 3 3 1 N-terminal CTNNB1 binding HMG_box PF00505.14 KFP02140.1 - 3e-22 78.6 1.0 5.8e-22 77.7 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP02140.1 - 2.8e-08 33.9 1.1 7.5e-08 32.6 0.7 1.7 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KFP02140.1 - 0.0057 15.9 0.3 0.0091 15.3 0.2 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Skp1 PF01466.14 KFP02141.1 - 9.2e-41 137.7 0.8 1.6e-40 137.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KFP02141.1 - 3.2e-29 100.7 0.6 8.5e-29 99.4 0.1 1.9 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain Metallophos PF00149.23 KFP02142.1 - 2.9e-41 141.0 0.7 3.8e-41 140.6 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YqzH PF14164.1 KFP02142.1 - 0.19 11.6 4.2 0.18 11.7 1.1 2.1 2 0 0 2 2 2 0 YqzH-like protein UQ_con PF00179.21 KFP02143.1 - 1.3e-51 173.7 0.1 1.4e-51 173.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP02143.1 - 4.1e-06 26.5 0.0 4.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFP02143.1 - 0.0048 16.7 0.1 0.0061 16.4 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KFP02143.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain zf-HC5HC2H_2 PF13832.1 KFP02144.1 - 2.5e-30 104.7 8.0 2.5e-30 104.7 5.5 2.9 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFP02144.1 - 6.6e-23 80.6 8.0 6.6e-23 80.6 5.5 3.7 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.4 KFP02144.1 - 1.5e-15 57.7 0.9 1.5e-15 57.7 0.7 2.9 2 1 2 4 4 4 1 Enhancer of polycomb-like PHD_2 PF13831.1 KFP02144.1 - 1e-12 47.1 6.7 1e-12 47.1 4.6 3.8 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 KFP02144.1 - 1.8e-09 37.1 8.1 1.8e-09 37.1 5.6 3.3 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 KFP02144.1 - 0.0041 16.8 4.3 0.0041 16.8 3.0 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Arf PF00025.16 KFP02145.1 - 7.7e-62 207.6 0.0 8.8e-62 207.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFP02145.1 - 4.6e-10 38.7 0.1 1.8e-07 30.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFP02145.1 - 7.5e-09 35.0 0.0 9.5e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFP02145.1 - 4.1e-07 30.5 0.0 6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFP02145.1 - 7e-07 28.7 0.0 7.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KFP02145.1 - 1.1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP02145.1 - 0.00031 20.2 0.0 0.0048 16.3 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP02145.1 - 0.0011 18.1 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFP02145.1 - 0.095 12.1 0.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CAML PF14963.1 KFP02146.1 - 3.8e-105 351.0 0.0 4.2e-105 350.8 0.0 1.0 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand FAM220 PF15487.1 KFP02147.1 - 0.13 11.6 1.1 0.17 11.2 0.8 1.2 1 0 0 1 1 1 0 FAM220 family Thioredoxin PF00085.15 KFP02148.1 - 1.6e-10 40.5 0.0 2.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pterin_4a PF01329.14 KFP02149.1 - 2e-31 107.5 0.2 2.3e-31 107.4 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.3 KFP02149.1 - 0.013 15.4 0.0 0.051 13.4 0.0 1.8 1 1 1 2 2 2 0 Translation-initiation factor 2 OAR PF03826.12 KFP02150.1 - 3.3e-09 35.9 1.0 8.6e-09 34.6 0.7 1.8 1 0 0 1 1 1 1 OAR domain Homeobox PF00046.24 KFP02150.1 - 0.055 13.0 1.1 0.11 12.1 0.7 1.5 1 0 0 1 1 1 0 Homeobox domain Macro PF01661.16 KFP02151.1 - 1.9e-26 92.3 0.0 3.4e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Macro domain Histone PF00125.19 KFP02151.1 - 1.4e-22 79.5 0.1 4e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFP02151.1 - 0.0062 16.5 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.15 KFP02151.1 - 0.025 14.4 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Clp amino terminal domain YihI PF04220.7 KFP02151.1 - 0.11 11.7 5.1 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) HLH PF00010.21 KFP02152.1 - 6.9e-17 60.8 0.1 6.9e-17 60.8 0.1 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IL8 PF00048.15 KFP02153.1 - 2.8e-08 33.5 1.4 3.8e-08 33.1 1.0 1.2 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DIM PF08194.7 KFP02153.1 - 0.95 9.4 3.7 1.5 8.8 2.5 1.4 1 0 0 1 1 1 0 DIM protein HCO3_cotransp PF00955.16 KFP02154.1 - 1.7e-72 244.7 2.9 2.3e-72 244.3 2.0 1.1 1 0 0 1 1 1 1 HCO3- transporter family Xan_ur_permease PF00860.15 KFP02154.1 - 0.0026 16.3 0.9 0.0026 16.3 0.6 2.0 2 0 0 2 2 2 1 Permease family DUF843 PF05814.6 KFP02154.1 - 4.6 7.1 5.7 1.8 8.3 1.3 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) ARID PF01388.16 KFP02155.1 - 9.7e-12 44.5 0.0 1e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BSP_II PF05432.6 KFP02156.1 - 0.0016 17.7 6.6 0.0025 17.1 4.6 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 KFP02156.1 - 0.017 14.6 2.5 0.025 14.0 1.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin Radial_spoke PF04712.7 KFP02156.1 - 0.023 13.4 3.1 0.033 12.9 2.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein ANAPC15 PF15243.1 KFP02156.1 - 0.065 13.3 6.5 0.13 12.3 4.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Myc_N PF01056.13 KFP02156.1 - 0.14 11.2 3.0 0.29 10.2 2.1 1.5 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KFP02156.1 - 0.2 11.9 6.8 0.36 11.1 4.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 KFP02156.1 - 0.41 9.0 2.3 0.55 8.6 1.6 1.1 1 0 0 1 1 1 0 Daxx Family Ribosomal_60s PF00428.14 KFP02156.1 - 2.3 8.6 12.7 5.7 7.4 8.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Abhydrolase_5 PF12695.2 KFP02158.1 - 6.4e-08 32.4 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family C2 PF00168.25 KFP02159.1 - 2.2e-20 72.2 0.0 4.7e-12 45.5 0.0 3.4 2 1 0 2 2 2 2 C2 domain Lectin_leg-like PF03388.8 KFP02160.1 - 2e-80 269.2 0.0 2.4e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family PMP1_2 PF08114.6 KFP02160.1 - 0.0036 16.7 0.3 0.0064 15.9 0.2 1.4 1 0 0 1 1 1 1 ATPase proteolipid family Col_cuticle_N PF01484.12 KFP02160.1 - 0.058 13.0 1.3 0.11 12.2 0.9 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF21 PF01595.15 KFP02161.1 - 3.5e-28 98.1 0.0 6.5e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KFP02161.1 - 2.2e-09 36.9 0.1 0.00029 20.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 KFP02161.1 - 0.0098 15.6 0.1 0.35 10.7 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Nrf1_DNA-bind PF10491.4 KFP02161.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Sema PF01403.14 KFP02162.1 - 1.6e-89 300.3 0.1 1.8e-89 300.2 0.1 1.0 1 0 0 1 1 1 1 Sema domain Sec63 PF02889.11 KFP02163.1 - 8.3e-20 71.2 0.6 1.3e-19 70.5 0.1 1.6 2 1 0 2 2 2 1 Sec63 Brl domain DUF603 PF04645.7 KFP02163.1 - 0.056 13.3 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 WD40 PF00400.27 KFP02164.1 - 1.4e-38 129.3 15.5 1.4e-12 46.9 1.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat SH3_2 PF07653.12 KFP02164.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain EMP24_GP25L PF01105.19 KFP02165.1 - 1.3e-44 152.1 0.0 1.5e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0128 PF03673.8 KFP02165.1 - 0.041 13.1 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) MRP-S24 PF14955.1 KFP02166.1 - 2e-47 160.4 0.0 2.2e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S24 zf-tcix PF14952.1 KFP02167.1 - 2.1e-20 71.7 5.9 5.2e-20 70.5 4.1 1.7 1 0 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Histone PF00125.19 KFP02168.1 - 3.3e-22 78.3 0.1 4.1e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFP02168.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone S-AdoMet_synt_C PF02773.11 KFP02169.1 - 6.6e-78 259.1 0.2 1.1e-77 258.4 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.15 KFP02169.1 - 3e-34 117.2 0.5 4.9e-34 116.5 0.3 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.11 KFP02169.1 - 6.9e-16 58.2 1.3 1e-15 57.7 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain Synaptobrevin PF00957.16 KFP02170.1 - 1.1e-25 89.0 0.1 1.1e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF4400 PF14348.1 KFP02170.1 - 0.022 14.1 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Sec20 PF03908.8 KFP02170.1 - 0.04 13.6 0.2 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 Sec20 M16C_assoc PF08367.6 KFP02170.1 - 0.065 12.0 0.2 0.076 11.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase M16C associated DUF607 PF04678.8 KFP02170.1 - 0.082 12.8 0.1 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 UCH PF00443.24 KFP02171.1 - 1.9e-42 145.2 0.2 2.4e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP02171.1 - 7.3e-08 32.1 0.2 1.4e-07 31.2 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFP02171.1 - 5.4e-05 23.2 0.2 0.00013 22.0 0.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Hexokinase_2 PF03727.11 KFP02172.1 - 5.6e-215 710.1 2.0 3.7e-107 357.0 0.2 2.4 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFP02172.1 - 1.1e-177 586.6 1.1 5.7e-89 296.8 0.1 2.3 2 0 0 2 2 2 2 Hexokinase DUF1997 PF09366.5 KFP02172.1 - 0.034 13.9 0.0 4.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1997) Rotavirus_VP3 PF06929.6 KFP02172.1 - 0.44 8.3 0.0 8.2 4.1 0.0 2.0 2 0 0 2 2 2 0 Rotavirus VP3 protein DUF347 PF03988.7 KFP02172.1 - 1.4 8.8 4.3 5.8 6.8 0.1 2.9 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) BTB PF00651.26 KFP02173.1 - 5.7e-15 55.2 0.0 2.5e-14 53.2 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFP02173.1 - 5.4e-07 29.3 0.7 1.8e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Annexin PF00191.15 KFP02174.1 - 5.6e-35 119.0 0.2 1.4e-25 88.9 0.0 2.0 2 0 0 2 2 2 2 Annexin Pkinase PF00069.20 KFP02175.1 - 4.9e-41 140.5 0.0 4.9e-41 140.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02175.1 - 1.6e-25 89.6 0.0 1.6e-25 89.6 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP02175.1 - 1.5e-06 27.4 0.0 1.5e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP02175.1 - 0.08 12.6 0.3 0.08 12.6 0.2 3.4 2 2 1 3 3 3 0 Phosphotransferase enzyme family BMP2K_C PF15282.1 KFP02177.1 - 6.4e-66 222.7 10.1 6.4e-66 222.7 7.0 2.4 2 1 0 2 2 2 2 BMP-2-inducible protein kinase C-terminus Nfu_N PF08712.6 KFP02178.1 - 1.8e-34 117.2 0.0 3e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KFP02178.1 - 1.4e-21 75.9 0.1 2e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 NifU-like domain SIS PF01380.17 KFP02179.1 - 3.4e-65 217.5 0.0 2.6e-34 117.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KFP02179.1 - 3.1e-28 98.5 0.0 1.8e-20 72.9 0.0 2.2 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFP02179.1 - 1.7e-17 63.5 0.0 4.4e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFP02179.1 - 2.3e-13 49.9 0.0 5.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KFP02179.1 - 4.1e-08 32.2 0.1 6.7e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KFP02179.1 - 0.0022 17.7 0.0 0.0062 16.2 0.0 1.8 1 0 0 1 1 1 1 SIS domain Ant_C PF05586.6 KFP02180.1 - 6.9e-42 141.8 0.4 8.3e-42 141.5 0.3 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region Sulfotransfer_1 PF00685.22 KFP02181.1 - 3.6e-35 121.5 0.3 4.5e-35 121.2 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFP02181.1 - 0.0024 17.5 0.2 0.0037 16.9 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase family Hist_deacetyl PF00850.14 KFP02182.1 - 1.6e-81 274.0 0.1 2.4e-81 273.4 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Laminin_G_2 PF02210.19 KFP02184.1 - 3e-102 337.6 0.3 3.1e-25 88.6 0.1 5.7 5 1 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.18 KFP02184.1 - 1.5e-75 251.4 0.0 9.6e-21 74.1 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_II PF06009.7 KFP02184.1 - 5.8e-33 113.5 2.2 5.8e-33 113.5 1.5 3.8 3 1 1 4 4 4 2 Laminin Domain II Laminin_EGF PF00053.19 KFP02184.1 - 5.8e-23 80.5 66.0 7.8e-10 38.5 9.7 5.6 4 1 1 5 5 5 3 Laminin EGF-like (Domains III and V) Laminin_G_3 PF13385.1 KFP02184.1 - 8.9e-18 65.0 0.3 0.0001 22.5 0.0 5.2 5 0 0 5 5 5 3 Concanavalin A-like lectin/glucanases superfamily Polysacc_lyase PF14099.1 KFP02184.1 - 0.0012 18.5 0.1 1.1 8.8 0.1 2.7 2 0 0 2 2 2 2 Polysaccharide lyase Laminin_I PF06008.9 KFP02184.1 - 0.087 12.1 18.1 0.48 9.6 0.1 3.8 3 1 1 4 4 4 0 Laminin Domain I hEGF PF12661.2 KFP02184.1 - 1.3 9.2 21.1 2.9 8.1 0.7 6.2 5 0 0 5 5 5 0 Human growth factor-like EGF Tubulin PF00091.20 KFP02185.1 - 1.9e-73 246.8 0.1 2.7e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFP02185.1 - 3.7e-29 101.3 0.0 6e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFP02185.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain DUF3469 PF11952.3 KFP02185.1 - 0.044 13.4 0.2 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) IGFBP PF00219.13 KFP02186.1 - 2.4e-12 47.1 22.0 2.4e-12 47.1 15.3 4.2 4 2 0 4 4 4 1 Insulin-like growth factor binding protein TSP_1 PF00090.14 KFP02186.1 - 5.2e-06 26.4 6.2 5.2e-06 26.4 4.3 2.7 2 0 0 2 2 2 1 Thrombospondin type 1 domain Cys_knot PF00007.17 KFP02186.1 - 1.8e-05 24.7 12.6 1.8e-05 24.7 8.8 3.5 2 1 1 3 3 3 1 Cystine-knot domain VWC PF00093.13 KFP02186.1 - 0.00063 19.7 0.2 0.00063 19.7 0.2 5.0 4 2 0 4 4 4 1 von Willebrand factor type C domain Pkinase_Tyr PF07714.12 KFP02188.1 - 2.2e-93 312.1 0.0 2.8e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP02188.1 - 4.9e-50 170.1 0.0 6.7e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP02188.1 - 2.1e-29 101.1 0.6 4.1e-29 100.1 0.2 1.7 2 0 0 2 2 2 1 SH2 domain SH3_1 PF00018.23 KFP02188.1 - 1.9e-21 75.1 0.4 1e-20 72.8 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFP02188.1 - 2.5e-14 52.5 0.4 5.5e-14 51.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFP02188.1 - 9.1e-13 47.4 0.0 3e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain APH PF01636.18 KFP02188.1 - 0.011 15.4 0.0 0.055 13.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH3_3 PF08239.6 KFP02188.1 - 0.082 13.1 0.1 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain YcaO PF02624.11 KFP02188.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 YcaO-like family SEFIR PF08357.6 KFP02189.1 - 8.2e-33 113.5 0.1 1.1e-32 113.1 0.1 1.2 1 0 0 1 1 1 1 SEFIR domain TIR_2 PF13676.1 KFP02189.1 - 0.00098 19.2 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 TIR domain DNA_pol_B PF00136.16 KFP02190.1 - 2.7e-88 296.7 0.0 6.7e-88 295.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KFP02190.1 - 2.1e-24 86.0 0.1 2e-14 53.1 0.0 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KFP02190.1 - 2.2e-12 46.8 11.6 1.8e-11 43.8 8.0 2.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta MFS_1 PF07690.11 KFP02191.1 - 1.3e-18 66.8 42.2 3.5e-10 39.1 17.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KFP02192.1 - 2e-29 102.4 44.0 2.5e-16 59.3 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.17 KFP02193.1 - 8.9e-05 21.9 0.0 9.7e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 Ras family ATP_bind_1 PF03029.12 KFP02193.1 - 0.082 12.4 0.0 0.093 12.2 0.0 1.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein rve PF00665.21 KFP02194.1 - 1.8e-16 60.2 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 KFP02194.1 - 6e-06 25.6 1.3 1.3e-05 24.5 0.9 1.5 1 0 0 1 1 1 1 Integrase Zinc binding domain FH2 PF02181.18 KFP02195.1 - 2.9e-97 325.8 11.1 1.5e-96 323.5 7.7 2.2 1 1 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 KFP02195.1 - 1.7e-61 207.0 4.0 1.7e-61 207.0 2.8 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 KFP02195.1 - 3.1e-51 173.4 0.7 1.1e-50 171.6 0.4 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain FlaC_arch PF05377.6 KFP02195.1 - 0.097 12.5 1.9 1 9.3 0.0 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Death PF00531.17 KFP02195.1 - 0.2 11.4 3.0 4.2 7.2 0.0 3.0 3 0 0 3 3 3 0 Death domain Ion_trans_2 PF07885.11 KFP02196.1 - 8.5e-34 115.1 15.3 3.5e-19 68.2 0.1 2.3 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.26 KFP02196.1 - 4.3e-05 22.8 10.4 0.011 14.9 1.2 2.2 1 1 1 2 2 2 2 Ion transport protein FUSC_2 PF13515.1 KFP02196.1 - 3.8 7.4 11.4 0.2 11.5 3.0 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein-like Ion_trans_2 PF07885.11 KFP02197.1 - 1.9e-31 107.5 11.1 3.1e-18 65.2 1.3 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 KFP02197.1 - 0.0018 17.5 4.0 0.015 14.5 0.2 2.3 2 0 0 2 2 2 2 Ion transport protein IRK PF01007.15 KFP02197.1 - 0.061 12.1 0.8 0.15 10.7 0.1 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP02198.1 - 1.7e-30 104.5 19.4 4.1e-18 64.8 1.6 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 KFP02198.1 - 0.059 12.6 9.7 0.28 10.4 0.4 2.4 2 0 0 2 2 2 0 Ion transport protein UPF0542 PF15086.1 KFP02198.1 - 0.07 12.8 0.5 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 7tm_2 PF00002.19 KFP02199.1 - 4.7e-79 264.9 25.1 6.1e-79 264.5 17.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP02199.1 - 7.7e-17 61.0 3.3 2e-16 59.7 2.3 1.8 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 KFP02199.1 - 8.3e-06 24.9 18.2 8.3e-06 24.9 12.6 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Glyoxalase PF00903.20 KFP02200.1 - 1e-25 90.1 0.0 1.2e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFP02200.1 - 1.4e-16 61.0 0.0 2.2e-16 60.3 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFP02200.1 - 6.5e-10 38.9 0.0 3.3e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BTB PF00651.26 KFP02201.1 - 7.6e-28 96.7 0.2 2.9e-26 91.6 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFP02201.1 - 4.7e-23 80.9 0.3 1e-21 76.6 0.2 2.4 1 1 1 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.20 KFP02201.1 - 7.2e-17 61.4 0.2 3.7e-07 30.0 0.1 2.2 2 0 0 2 2 2 2 F5/8 type C domain zf-AN1 PF01428.11 KFP02202.1 - 3e-11 42.9 7.0 8.4e-11 41.5 4.9 1.8 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 KFP02202.1 - 0.12 12.2 8.8 0.053 13.3 3.5 2.1 2 0 0 2 2 2 0 IBR domain zf-RING_4 PF14570.1 KFP02202.1 - 0.47 10.0 4.8 1.1 8.8 3.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Yae1_N PF09811.4 KFP02203.1 - 3.1e-10 39.3 30.3 0.0011 18.4 13.4 3.2 2 1 0 2 2 2 2 Essential protein Yae1, N terminal I-set PF07679.11 KFP02204.1 - 1.8e-60 200.7 0.0 1.4e-11 44.0 0.0 6.4 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP02204.1 - 8.7e-55 182.8 6.1 8.3e-09 35.4 0.0 6.9 7 0 0 7 7 7 6 Immunoglobulin domain MAM PF00629.18 KFP02204.1 - 4.9e-50 169.4 0.0 1.4e-49 167.9 0.0 1.8 2 0 0 2 2 2 1 MAM domain ig PF00047.20 KFP02204.1 - 1.7e-36 124.1 5.5 4.6e-06 26.6 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 KFP02204.1 - 1.3e-35 121.6 13.5 2.7e-08 34.1 0.0 7.2 7 0 0 7 7 7 6 Immunoglobulin domain V-set PF07686.12 KFP02204.1 - 4e-31 107.2 9.3 2e-06 27.6 0.0 9.1 6 3 1 7 7 7 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP02204.1 - 1.6e-10 40.7 3.8 0.028 14.3 0.0 5.5 5 0 0 5 5 5 4 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFP02204.1 - 3.4e-05 23.7 1.8 0.11 12.5 0.0 4.3 4 0 0 4 4 4 1 Immunoglobulin C1-set domain BiPBP_C PF06832.7 KFP02204.1 - 0.011 15.6 0.0 0.32 10.9 0.0 3.2 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family CCDC-167 PF15188.1 KFP02205.1 - 7.7e-28 96.2 2.5 8.4e-28 96.1 1.7 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Strep_SA_rep PF06696.6 KFP02205.1 - 0.011 15.5 0.4 0.021 14.5 0.3 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Mnd1 PF03962.10 KFP02205.1 - 0.075 12.6 2.2 0.086 12.4 1.5 1.0 1 0 0 1 1 1 0 Mnd1 family FtsJ PF01728.14 KFP02206.1 - 1.4e-37 129.4 0.0 2.5e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.18 KFP02206.1 - 1.4e-12 47.2 2.5 1.4e-12 47.2 1.8 2.1 2 0 0 2 2 2 1 G-patch domain WW PF00397.21 KFP02206.1 - 0.00067 19.4 1.3 0.0056 16.5 0.0 2.4 2 0 0 2 2 2 1 WW domain mRNA_cap_enzyme PF01331.14 KFP02206.1 - 0.0024 17.6 0.0 0.0065 16.1 0.0 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 KFP02206.1 - 0.011 15.0 0.9 0.024 13.9 0.1 1.8 2 0 0 2 2 2 0 ATP dependent DNA ligase domain G-patch_2 PF12656.2 KFP02206.1 - 0.13 12.1 3.4 0.094 12.5 0.9 1.9 2 0 0 2 2 2 0 DExH-box splicing factor binding site zf-C3HC4_3 PF13920.1 KFP02207.1 - 1.2e-10 40.8 8.9 1.2e-10 40.8 6.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP02207.1 - 1.6e-10 40.6 12.2 3.7e-10 39.4 7.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFP02207.1 - 7.6e-10 38.2 15.0 1.1e-09 37.7 8.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP02207.1 - 3.5e-08 33.1 7.5 3.5e-08 33.1 5.2 2.3 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KFP02207.1 - 3.5e-08 33.3 12.0 3.5e-08 33.3 8.3 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP02207.1 - 8.6e-08 31.7 11.2 8.6e-08 31.7 7.7 2.1 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFP02207.1 - 3.1e-06 26.7 9.1 9.4e-05 22.0 1.7 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_6 PF14835.1 KFP02207.1 - 6.9e-05 22.5 5.4 6.9e-05 22.5 3.7 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KFP02207.1 - 0.0001 22.3 10.5 0.0001 22.3 7.3 2.4 3 1 0 3 3 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFP02207.1 - 0.00038 20.2 4.0 0.00099 18.9 2.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KFP02207.1 - 0.036 13.6 7.1 0.087 12.3 4.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFP02207.1 - 0.12 11.9 9.9 0.83 9.2 7.1 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 KFP02207.1 - 0.17 11.7 0.3 0.17 11.7 0.2 2.6 1 1 1 2 2 2 0 zinc-ribbons FdhE PF04216.7 KFP02207.1 - 0.2 11.3 8.9 0.24 11.0 5.8 1.5 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation YdjO PF14169.1 KFP02207.1 - 0.79 9.2 8.9 1.5 8.2 0.6 3.4 3 1 0 3 3 3 0 Cold-inducible protein YdjO zinc_ribbon_5 PF13719.1 KFP02207.1 - 1.7 8.2 9.0 5.2 6.7 0.2 3.4 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFP02207.1 - 2.1 8.1 9.5 4.7 6.9 0.2 3.4 3 1 1 4 4 4 0 zinc-ribbon domain Baculo_RING PF05883.6 KFP02207.1 - 2.7 7.8 9.9 0.86 9.4 3.0 2.3 1 1 1 2 2 2 0 Baculovirus U-box/Ring-like domain FHA PF00498.21 KFP02208.1 - 2.4e-16 59.5 0.0 3.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 FHA domain tRNA-synt_2c PF01411.14 KFP02209.1 - 1.9e-187 623.9 0.0 2.4e-187 623.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFP02209.1 - 6.2e-08 32.4 1.2 9.5e-08 31.8 0.1 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KFP02209.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 DHHA1 domain LRR_6 PF13516.1 KFP02210.1 - 3.7e-17 60.4 22.9 6.5e-05 22.5 0.0 7.8 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 KFP02210.1 - 6.8e-09 35.1 11.7 0.00017 21.1 0.2 4.0 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP02210.1 - 0.00019 21.0 12.6 1.5 9.1 0.0 6.4 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.1 KFP02210.1 - 0.048 13.4 23.2 0.32 10.7 1.4 4.6 2 1 0 4 4 4 0 Leucine rich repeat TMEM151 PF14857.1 KFP02211.1 - 1.4e-231 768.4 18.8 1.7e-231 768.2 13.0 1.0 1 0 0 1 1 1 1 TMEM151 family UAA PF08449.6 KFP02212.1 - 2.4e-89 299.2 21.2 3e-89 298.9 14.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFP02212.1 - 8.3e-08 32.3 21.2 3.7e-06 27.0 8.1 3.0 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 KFP02212.1 - 0.0098 15.5 19.6 0.073 12.7 13.5 2.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family Neurensin PF14927.1 KFP02212.1 - 2.5 7.4 5.7 2.1 7.7 0.2 2.7 1 1 0 2 2 2 0 Neurensin HSP90 PF00183.13 KFP02213.1 - 2.9e-268 890.5 35.0 3.5e-268 890.3 24.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KFP02213.1 - 5.9e-11 42.0 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFP02213.1 - 1.9e-10 40.5 0.1 7.4e-10 38.6 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.9 KFP02213.1 - 0.41 8.6 12.6 0.75 7.7 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Nucleoside_tran PF01733.13 KFP02214.1 - 7.9e-107 356.9 10.8 1.2e-106 356.3 7.5 1.3 1 0 0 1 1 1 1 Nucleoside transporter Spectrin PF00435.16 KFP02216.1 - 0.0077 16.5 2.1 3.9 7.8 0.9 2.5 2 1 0 2 2 2 2 Spectrin repeat PilJ PF13675.1 KFP02216.1 - 0.054 13.8 0.4 0.076 13.3 0.3 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Peptidase_C2 PF00648.16 KFP02217.1 - 3.1e-150 499.2 0.0 4.3e-150 498.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFP02217.1 - 1.2e-60 203.4 0.0 2.1e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.1 KFP02217.1 - 1.2e-07 30.9 1.2 0.016 15.0 0.0 5.1 3 1 1 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 KFP02217.1 - 6.6e-07 28.1 1.8 0.031 13.5 0.0 4.8 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 KFP02217.1 - 1.3e-06 28.4 2.9 0.033 14.3 0.1 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP02217.1 - 1.3e-05 24.6 2.3 0.0013 18.3 0.2 3.7 3 0 0 3 3 3 1 EF-hand domain pair DUF221 PF02714.10 KFP02218.1 - 2.8e-94 315.6 21.1 5.6e-94 314.6 14.6 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFP02218.1 - 5.6e-20 71.4 0.0 5.6e-20 71.4 0.0 5.7 6 1 1 7 7 7 2 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFP02218.1 - 1.6e-11 44.5 0.2 3.9e-11 43.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 KFP02218.1 - 0.045 13.3 0.1 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4006 PF13179.1 KFP02218.1 - 3.4 7.2 5.1 42 3.7 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Ribosomal_L14 PF00238.14 KFP02219.1 - 2.9e-24 85.1 0.0 3.6e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e potato_inhibit PF00280.13 KFP02219.1 - 0.032 14.3 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Potato inhibitor I family VEGF_C PF14554.1 KFP02220.1 - 3e-28 97.3 14.8 3e-28 97.3 10.3 2.3 2 0 0 2 2 2 1 VEGF heparin-binding domain PDGF PF00341.12 KFP02220.1 - 1.6e-27 95.4 5.7 1.6e-27 95.4 4.0 2.2 2 1 1 3 3 3 1 PDGF/VEGF domain Yae1_N PF09811.4 KFP02221.1 - 2.8e-20 71.5 64.3 1.5e+04 -25.0 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Radial_spoke PF04712.7 KFP02222.1 - 4.6e-06 25.6 0.1 2.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Radial spokehead-like protein EHN PF06441.7 KFP02223.1 - 6.4e-36 122.6 0.1 1.1e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFP02223.1 - 2.3e-16 60.4 0.0 2.3e-15 57.1 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP02223.1 - 8.8e-13 48.3 0.0 2.1e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold p31comet PF06581.7 KFP02224.1 - 8.7e-66 221.4 0.0 1e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding GTP_EFTU PF00009.22 KFP02225.1 - 7.5e-28 97.2 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFP02225.1 - 1.2e-09 38.2 0.8 3.6e-09 36.7 0.5 1.9 1 1 1 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFP02225.1 - 0.00012 22.1 0.2 0.00045 20.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KFP02225.1 - 0.00087 18.7 0.1 12 5.3 0.0 3.5 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KFP02225.1 - 0.0017 18.2 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFP02225.1 - 0.014 15.8 0.0 0.14 12.6 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 KFP02225.1 - 0.042 13.0 0.1 5 6.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFP02225.1 - 0.047 12.9 0.1 3 7.0 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KFP02225.1 - 0.077 12.8 0.2 1.8 8.3 0.1 2.3 1 1 1 2 2 2 0 Dynamin family DUF4461 PF14688.1 KFP02225.1 - 0.099 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) IMS_C PF11799.3 KFP02226.1 - 2.7e-13 49.9 0.0 5.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.15 KFP02226.1 - 2.2e-08 34.0 0.0 9.1e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 impB/mucB/samB family Xpo1 PF08389.7 KFP02227.1 - 2e-36 125.1 2.4 8.9e-36 123.0 1.3 2.4 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 KFP02227.1 - 0.00031 20.5 0.0 0.0019 18.0 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain RNA_pol_A_bac PF01000.21 KFP02228.1 - 6.6e-30 103.5 0.0 1.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFP02228.1 - 2.1e-16 58.7 0.0 2.6e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Yip1 PF04893.12 KFP02229.1 - 1.4e-06 27.9 18.2 2e-06 27.3 12.5 1.5 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.4 KFP02229.1 - 0.012 15.7 1.4 0.034 14.3 1.0 1.9 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Yip1 PF04893.12 KFP02230.1 - 3.1e-06 26.8 20.2 6e-06 25.8 14.0 1.5 1 1 0 1 1 1 1 Yip1 domain Romo1 PF10247.4 KFP02230.1 - 0.014 15.6 2.7 0.038 14.2 1.6 2.1 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 ABC2_membrane_3 PF12698.2 KFP02230.1 - 0.72 8.8 14.2 1 8.3 9.8 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein LRR_6 PF13516.1 KFP02231.1 - 1.6e-13 49.1 6.7 0.014 15.4 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 KFP02231.1 - 3.2e-07 29.4 1.1 5.2 7.4 0.0 5.3 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.2 KFP02231.1 - 7.2e-07 28.6 5.1 0.0038 16.8 0.0 4.0 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFP02231.1 - 6.2e-06 25.5 1.9 11 6.7 0.0 5.4 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 KFP02231.1 - 0.002 17.8 2.4 2.3 8.0 0.1 3.8 3 2 0 3 3 3 2 Leucine rich repeat Pilt PF15453.1 KFP02232.1 - 1.2e-115 386.6 31.8 6.5e-89 298.7 13.8 3.8 2 2 2 4 4 4 2 Protein incorporated later into Tight Junctions Fib_alpha PF08702.5 KFP02232.1 - 0.056 13.5 5.6 0.1 12.6 3.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ERM PF00769.14 KFP02232.1 - 0.11 12.0 14.2 0.21 11.1 9.9 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Lebercilin PF15619.1 KFP02232.1 - 0.19 11.1 19.0 1.2 8.5 13.1 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.14 KFP02232.1 - 4.6 4.9 6.9 6.3 4.5 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFP02232.1 - 5.5 6.5 19.4 1.2e+02 2.2 13.3 2.4 1 1 1 2 2 2 0 IncA protein Syntaxin-6_N PF09177.6 KFP02232.1 - 5.8 7.3 10.5 0.7 10.3 1.1 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal EGF PF00008.22 KFP02233.1 - 6.3e-29 99.5 78.8 3.3e-08 33.3 5.6 6.4 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.2 KFP02233.1 - 1e-11 44.0 54.8 0.0035 17.3 2.8 7.7 7 0 0 7 7 7 6 Human growth factor-like EGF EGF_2 PF07974.8 KFP02233.1 - 5.4e-09 36.0 101.5 0.024 14.7 5.9 6.4 6 0 0 6 6 6 5 EGF-like domain Laminin_EGF PF00053.19 KFP02233.1 - 0.053 13.4 84.7 0.26 11.2 11.2 6.4 2 2 4 6 6 6 0 Laminin EGF-like (Domains III and V) EGF_CA PF07645.10 KFP02233.1 - 1.8 8.6 87.8 0.083 12.8 4.8 6.4 3 1 3 6 6 6 0 Calcium-binding EGF domain zf-C2H2_jaz PF12171.3 KFP02234.1 - 0.00037 20.5 1.8 0.00037 20.5 1.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP02234.1 - 0.016 15.3 2.4 1.9 8.6 0.2 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFP02234.1 - 5.7 7.2 14.8 0.15 12.2 1.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2465 PF10239.4 KFP02235.1 - 1.2e-134 448.5 0.0 1.4e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) RasGEF PF00617.14 KFP02236.1 - 1.9e-47 161.4 0.4 3.3e-47 160.6 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain EF-hand_7 PF13499.1 KFP02236.1 - 1.2e-12 47.7 0.2 8.2e-06 25.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair C1_1 PF00130.17 KFP02236.1 - 1.6e-12 46.9 9.3 3.6e-12 45.8 6.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RasGEF_N PF00618.15 KFP02236.1 - 5.4e-11 42.5 0.1 2.2e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif EF-hand_1 PF00036.27 KFP02236.1 - 2.3e-09 35.8 6.3 0.00014 20.8 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFP02236.1 - 3.8e-09 35.6 1.6 0.00025 20.6 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KFP02236.1 - 2.1e-08 33.1 0.3 0.0073 15.5 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFP02236.1 - 1.3e-05 24.7 1.6 0.089 12.4 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair EGF_CA PF07645.10 KFP02237.1 - 2.4e-101 331.5 240.6 1.8e-09 37.4 4.3 17.6 17 1 0 17 17 17 15 Calcium-binding EGF domain TB PF00683.12 KFP02237.1 - 1.3e-52 175.0 64.3 1.4e-16 59.7 4.8 6.3 6 0 0 6 6 6 4 TB domain cEGF PF12662.2 KFP02237.1 - 9.3e-50 165.8 142.0 2.5e-07 30.2 2.2 16.8 16 1 0 16 16 16 12 Complement Clr-like EGF-like EGF PF00008.22 KFP02237.1 - 2.7e-36 123.0 215.2 0.00012 21.9 2.6 18.1 17 0 0 17 17 17 13 EGF-like domain EGF_3 PF12947.2 KFP02237.1 - 5.1e-19 67.9 185.0 0.0008 19.3 1.1 18.0 17 0 0 17 17 17 13 EGF domain FXa_inhibition PF14670.1 KFP02237.1 - 3.4e-12 46.2 244.3 0.00027 20.9 5.1 18.6 16 3 3 19 19 19 13 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 KFP02237.1 - 4.3e-06 26.4 56.0 0.0001 21.9 24.3 9.3 6 3 3 9 9 9 4 Plasmodium ookinete surface protein Pvs28 EGF_MSP1_1 PF12946.2 KFP02237.1 - 0.0011 18.7 1.3 0.0011 18.7 0.9 18.0 19 1 0 19 19 19 6 MSP1 EGF domain 1 hEGF PF12661.2 KFP02237.1 - 0.0048 16.8 2.9 0.0048 16.8 2.0 14.3 14 0 0 14 14 14 3 Human growth factor-like EGF Lipase_GDSL_2 PF13472.1 KFP02238.1 - 2.7e-07 30.8 0.0 6.3e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TLV_coat PF00429.14 KFP02239.1 - 0.0038 15.7 0.2 0.004 15.6 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) TipAS PF07739.8 KFP02239.1 - 0.049 13.9 0.0 0.055 13.7 0.0 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Alpha-amylase PF00128.19 KFP02240.1 - 7e-21 74.9 0.0 1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KFP02240.1 - 5.5e-13 48.8 0.7 4.3e-12 46.0 0.2 2.3 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain RRM_6 PF14259.1 KFP02241.1 - 5.5e-12 45.4 0.2 4.9e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP02241.1 - 1.4e-11 43.8 0.3 4.4e-07 29.4 0.2 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP02241.1 - 9.2e-09 35.0 0.1 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRCT PF00533.21 KFP02242.1 - 7.8e-19 67.6 3.4 2.7e-05 24.2 0.0 3.6 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFP02242.1 - 3.1e-17 62.1 2.9 2.6e-15 56.0 0.2 3.5 3 0 0 3 3 3 1 twin BRCT domain Spectrin PF00435.16 KFP02242.1 - 0.0056 16.9 1.4 0.087 13.1 0.9 2.4 1 1 1 2 2 2 1 Spectrin repeat Pik1 PF11522.3 KFP02242.1 - 0.018 14.7 1.8 0.22 11.2 0.2 3.1 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 V_ATPase_I PF01496.14 KFP02242.1 - 0.2 9.4 0.8 0.31 8.8 0.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.13 KFP02242.1 - 0.26 11.0 1.4 6.7 6.4 0.0 2.9 3 1 0 3 3 3 0 Cobalamin adenosyltransferase Fibrinogen_C PF00147.13 KFP02243.1 - 9.2e-66 221.8 7.0 1.6e-65 221.0 4.9 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DivIC PF04977.10 KFP02243.1 - 0.013 14.9 2.5 0.013 14.9 1.8 3.7 2 1 3 5 5 5 0 Septum formation initiator SlyX PF04102.7 KFP02243.1 - 0.12 12.7 24.5 0.074 13.4 5.1 3.0 1 1 2 3 3 3 0 SlyX Herpes_UL6 PF01763.11 KFP02243.1 - 0.3 9.1 12.4 0.42 8.7 8.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4239 PF14023.1 KFP02243.1 - 0.83 8.9 7.8 1.3 8.3 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Phage_lysis PF03245.8 KFP02243.1 - 4.4 7.2 13.1 0.096 12.6 3.1 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Acyltransferase PF01553.16 KFP02244.1 - 3.2e-19 68.6 0.0 6.8e-19 67.6 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase Tmemb_14 PF03647.8 KFP02245.1 - 1.2e-15 57.6 1.0 1.2e-15 57.6 0.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Gly-zipper_OmpA PF13436.1 KFP02245.1 - 0.14 11.8 0.4 0.14 11.8 0.2 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Myco_arth_vir_N PF09610.5 KFP02245.1 - 0.26 11.2 0.6 0.26 11.2 0.4 2.1 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) CbtA PF09490.5 KFP02245.1 - 0.29 10.3 1.5 0.36 10.1 1.0 1.0 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) GST_N PF02798.15 KFP02246.1 - 2.3e-18 66.1 0.0 5e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFP02246.1 - 1e-16 60.6 0.0 1.7e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFP02246.1 - 0.0013 18.5 0.3 0.0035 17.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFP02246.1 - 0.003 17.7 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFP02246.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFP02247.1 - 3.4e-17 62.3 0.0 6.8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFP02247.1 - 1.2e-12 47.6 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFP02247.1 - 0.005 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFP02247.1 - 0.027 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFP02247.1 - 0.031 14.1 0.1 0.11 12.3 0.0 2.1 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFP02248.1 - 2e-18 66.2 0.0 5.1e-18 65.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFP02248.1 - 1.3e-15 57.1 0.0 2.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFP02248.1 - 0.0038 17.4 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFP02248.1 - 0.0039 17.6 0.0 0.0064 16.9 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFP02248.1 - 0.007 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 KFP02249.1 - 1e-75 254.2 0.0 1.5e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02249.1 - 2.6e-37 128.3 0.1 1.1e-36 126.3 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP02249.1 - 0.0072 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SRP-alpha_N PF04086.8 KFP02249.1 - 0.033 13.5 2.5 0.051 12.9 1.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal tRNA-synt_1g PF09334.6 KFP02249.1 - 0.088 11.4 0.3 0.15 10.7 0.2 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) F-box-like PF12937.2 KFP02250.1 - 1.3e-11 44.0 1.5 2.4e-11 43.1 1.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFP02250.1 - 2.9e-08 33.1 1.5 5.5e-08 32.2 1.0 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 KFP02250.1 - 0.00039 20.2 0.8 0.00069 19.4 0.6 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 KFP02250.1 - 0.036 13.7 0.2 0.068 12.8 0.2 1.4 1 0 0 1 1 1 0 TPR repeat Elongin_A PF06881.6 KFP02250.1 - 0.11 12.9 2.9 0.69 10.3 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A GCM PF03615.10 KFP02251.1 - 9.5e-75 248.9 5.5 1.3e-74 248.5 3.8 1.2 1 0 0 1 1 1 1 GCM motif protein ELO PF01151.13 KFP02252.1 - 7.4e-69 231.8 25.1 9.3e-69 231.4 17.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GCS PF03074.11 KFP02253.1 - 6.1e-198 657.3 0.3 7.5e-198 657.0 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 KFP02253.1 - 0.021 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Kelch_1 PF01344.20 KFP02254.1 - 1.7e-50 168.2 6.9 3.2e-12 45.7 0.0 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFP02254.1 - 2.4e-36 122.3 8.0 1.3e-09 37.7 0.1 6.2 1 1 5 6 6 6 5 Kelch motif BACK PF07707.10 KFP02254.1 - 2.7e-26 91.4 0.4 7e-26 90.0 0.3 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFP02254.1 - 7.3e-24 83.3 1.0 9e-06 25.7 0.0 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP02254.1 - 1.4e-23 82.3 0.3 3.9e-05 23.3 0.0 5.7 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.26 KFP02254.1 - 6.2e-23 80.8 1.5 8.8e-23 80.4 0.4 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KFP02254.1 - 2.5e-22 77.7 4.1 1.5e-08 34.0 0.1 6.5 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 KFP02254.1 - 1.3e-13 50.5 5.5 0.00053 19.8 0.2 5.6 5 0 0 5 5 5 4 Kelch motif DUF1668 PF07893.8 KFP02254.1 - 0.015 14.4 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) ThiG PF05690.9 KFP02254.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG LRR_4 PF12799.2 KFP02255.1 - 4.1e-45 150.7 51.4 1.8e-08 33.7 0.1 9.1 5 3 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP02255.1 - 2.7e-33 113.5 39.4 7.4e-09 35.2 3.2 6.8 3 2 3 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KFP02255.1 - 4.2e-24 80.8 47.3 0.1 12.7 0.0 14.6 15 0 0 15 15 15 10 Leucine Rich Repeat LRR_7 PF13504.1 KFP02255.1 - 7e-12 43.4 50.8 1.8 9.0 0.1 14.9 15 0 0 15 15 15 7 Leucine rich repeat LRR_9 PF14580.1 KFP02255.1 - 3.8e-07 29.8 13.5 0.0019 17.8 2.1 4.2 2 1 2 4 4 4 3 Leucine-rich repeat DUF2322 PF10084.4 KFP02255.1 - 0.12 12.1 0.1 2.5 7.9 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) BLOC1_2 PF10046.4 KFP02255.1 - 0.18 11.9 2.1 0.35 11.0 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MLIP PF15274.1 KFP02256.1 - 9e-68 228.5 2.8 1.7e-67 227.6 1.9 1.4 1 0 0 1 1 1 1 Muscular LMNA-interacting protein Peptidase_C1 PF00112.18 KFP02257.1 - 1.9e-53 181.5 6.4 1.9e-53 181.5 4.4 1.7 2 0 0 2 2 2 1 Papain family cysteine protease Pacifastin_I PF05375.8 KFP02257.1 - 0.00033 20.1 3.0 0.0014 18.1 2.1 2.1 1 0 0 1 1 1 1 Pacifastin inhibitor (LCMII) Propeptide_C1 PF08127.8 KFP02257.1 - 0.0011 18.5 0.0 0.0029 17.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C1 propeptide Somatomedin_B PF01033.12 KFP02257.1 - 0.021 14.7 16.9 0.021 14.7 11.7 2.4 2 0 0 2 2 2 0 Somatomedin B domain Peptidase_C1_2 PF03051.10 KFP02257.1 - 0.045 12.2 2.9 0.034 12.6 0.6 1.8 3 0 0 3 3 3 0 Peptidase C1-like family DUF1669 PF07894.7 KFP02258.1 - 1.5e-107 359.0 0.0 4e-107 357.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1669) PLDc_2 PF13091.1 KFP02258.1 - 2.3e-08 33.8 0.1 4.7e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 PLD-like domain Regulator_TrmB PF11495.3 KFP02258.1 - 0.02 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB 7tm_1 PF00001.16 KFP02259.1 - 2.1e-59 200.7 21.6 2.7e-59 200.3 15.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Orexin_rec2 PF03827.8 KFP02259.1 - 5.6e-25 87.1 0.6 5.6e-25 87.1 0.4 2.1 2 0 0 2 2 2 1 Orexin receptor type 2 7TM_GPCR_Srsx PF10320.4 KFP02259.1 - 5.5e-05 22.4 20.8 0.00018 20.7 14.4 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx ABC2_membrane_5 PF13346.1 KFP02259.1 - 0.054 12.7 16.1 0.23 10.7 3.1 3.3 2 1 1 3 3 3 0 ABC-2 family transporter protein DUF2231 PF09990.4 KFP02259.1 - 2.1 8.7 8.3 0.44 10.9 2.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) GDNF PF02351.11 KFP02260.1 - 2.3e-21 76.0 51.9 4.5e-11 43.0 10.6 3.6 3 1 0 3 3 3 3 GDNF/GAS1 domain HMGL-like PF00682.14 KFP02262.1 - 1.4e-67 227.8 0.0 1.6e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 HMGL-like TGFb_propeptide PF00688.13 KFP02263.1 - 2.3e-58 197.3 0.2 7.8e-58 195.5 0.1 1.8 1 1 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFP02263.1 - 4.6e-44 148.9 1.0 1e-43 147.8 0.7 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain YkuD_2 PF13645.1 KFP02263.1 - 0.072 12.3 0.3 0.15 11.3 0.2 1.5 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Spectrin PF00435.16 KFP02264.1 - 1.4e-225 732.4 482.5 8.9e-17 61.3 4.8 42.5 39 4 4 44 44 44 33 Spectrin repeat GAS2 PF02187.12 KFP02264.1 - 2.8e-34 116.6 1.0 8.7e-34 115.1 0.7 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 KFP02264.1 - 2.5e-30 104.7 12.3 5.3e-16 58.6 0.0 7.7 7 0 0 7 7 7 2 Calponin homology (CH) domain EF-hand_1 PF00036.27 KFP02264.1 - 2.2e-12 45.3 2.3 5.4e-05 22.1 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP02264.1 - 6.3e-10 38.1 2.4 0.00066 19.3 0.4 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFP02264.1 - 1e-09 37.8 0.2 3.3e-07 29.7 0.1 3.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 KFP02264.1 - 1.6e-09 37.7 0.6 1.6e-09 37.7 0.4 3.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP02264.1 - 1e-08 34.1 4.1 3.9e-05 22.7 1.0 3.2 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 KFP02264.1 - 1.1e-07 31.3 0.0 3.8e-05 23.2 0.0 4.0 2 0 0 2 2 2 1 CAMSAP CH domain Laminin_II PF06009.7 KFP02264.1 - 0.0083 15.8 0.3 0.0083 15.8 0.2 31.0 24 7 5 34 34 34 3 Laminin Domain II RCR PF12273.3 KFP02265.1 - 0.18 12.3 0.4 0.18 12.3 0.3 1.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF4131 PF13567.1 KFP02265.1 - 7.1 6.0 6.1 10 5.4 4.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) BEN PF10523.4 KFP02266.1 - 3.4e-08 33.4 0.0 7.9e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 BEN domain bZIP_2 PF07716.10 KFP02266.1 - 0.72 9.7 3.0 0.32 10.8 0.2 1.8 2 0 0 2 2 2 0 Basic region leucine zipper zf-C2H2_4 PF13894.1 KFP02267.1 - 0.019 15.2 1.4 0.019 15.2 1.0 13.9 14 0 0 14 14 14 0 C2H2-type zinc finger DUF2951 PF11166.3 KFP02267.1 - 4.4 7.2 6.8 0.94 9.3 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) BAG PF02179.11 KFP02268.1 - 1.1e-08 35.0 0.2 2.6e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 BAG domain Enkurin PF13864.1 KFP02268.1 - 1 9.6 5.3 14 5.9 0.6 2.3 2 0 0 2 2 2 0 Calmodulin-binding Ras PF00071.17 KFP02269.1 - 1.5e-53 180.4 1.4 2.2e-53 179.9 0.9 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP02269.1 - 9.7e-20 71.2 0.2 1.8e-19 70.4 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP02269.1 - 2.3e-10 40.0 0.9 3.1e-10 39.5 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP02269.1 - 3e-07 30.4 0.1 6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP02269.1 - 1.5e-05 24.5 0.4 5.6e-05 22.6 0.3 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP02269.1 - 4.9e-05 22.5 0.1 7.3e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFP02269.1 - 0.005 16.1 0.3 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KFP02269.1 - 0.0054 16.3 4.1 0.012 15.2 0.6 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein YwhD PF08741.5 KFP02269.1 - 0.014 14.7 0.1 0.028 13.8 0.0 1.4 1 1 0 1 1 1 0 YwhD family MobB PF03205.9 KFP02269.1 - 0.14 11.9 0.7 0.33 10.6 0.2 1.9 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DNA_primase_lrg PF04104.9 KFP02270.1 - 8.9e-90 300.4 0.0 1.8e-89 299.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit 7tm_2 PF00002.19 KFP02271.1 - 1.8e-74 249.8 9.0 2.2e-74 249.6 6.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1129 PF06570.6 KFP02271.1 - 0.023 13.9 2.1 0.057 12.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Condensin2nSMC PF12422.3 KFP02272.1 - 7.2e-67 223.8 5.8 1.7e-51 173.9 0.4 4.6 5 0 0 5 5 5 2 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 KFP02272.1 - 2.5e-08 33.3 0.9 1.2 9.4 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 KFP02272.1 - 3e-06 27.4 0.0 0.034 14.4 0.0 3.1 1 1 1 2 2 2 2 HEAT repeats RPAP3_C PF13877.1 KFP02272.1 - 0.01 15.7 0.1 2.6 8.0 0.1 3.2 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 TIP120 PF08623.5 KFP02272.1 - 0.016 14.7 0.3 0.46 10.0 0.0 3.2 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.2 KFP02272.1 - 0.037 14.3 0.1 0.99 9.8 0.0 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF577 PF04510.7 KFP02272.1 - 0.069 12.8 10.3 0.28 10.8 0.0 4.6 7 0 0 7 7 7 0 Family of unknown function (DUF577) Tautomerase PF01361.16 KFP02272.1 - 0.083 12.5 0.0 0.29 10.7 0.0 2.0 1 0 0 1 1 1 0 Tautomerase enzyme Y_phosphatase PF00102.22 KFP02274.1 - 1.5e-73 247.0 0.4 2.1e-73 246.5 0.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP02274.1 - 0.001 18.6 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFP02274.1 - 0.023 14.7 0.9 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate DnaJ PF00226.26 KFP02275.1 - 7.9e-30 102.3 4.0 1.3e-29 101.7 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain Catalase-rel PF06628.7 KFP02275.1 - 0.014 15.2 0.6 0.036 13.9 0.1 1.8 2 0 0 2 2 2 0 Catalase-related immune-responsive HECT PF00632.20 KFP02276.1 - 3.6e-94 315.4 0.0 6.1e-94 314.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KFP02276.1 - 0.00037 19.8 0.1 0.001 18.5 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Homeobox PF00046.24 KFP02277.1 - 3.2e-23 81.0 6.7 4.4e-23 80.6 4.7 1.2 1 0 0 1 1 1 1 Homeobox domain QLQ PF08880.6 KFP02277.1 - 0.00079 18.7 0.2 0.00079 18.7 0.2 1.8 3 0 0 3 3 3 1 QLQ HA PF03457.9 KFP02277.1 - 0.18 11.9 2.0 0.33 11.0 1.4 1.6 1 1 0 1 1 1 0 Helicase associated domain MA3 PF02847.12 KFP02278.1 - 4.4e-25 87.5 0.9 4.4e-25 87.5 0.6 2.4 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KFP02278.1 - 2.7e-23 82.4 5.5 2.7e-23 82.4 3.8 2.3 2 1 0 2 2 2 1 MIF4G domain LMBR1 PF04791.11 KFP02279.1 - 7.1e-145 483.2 23.1 1.9e-144 481.7 16.0 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF912 PF06024.7 KFP02279.1 - 0.052 13.5 0.2 0.052 13.5 0.2 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 60KD_IMP PF02096.15 KFP02279.1 - 0.07 12.7 7.9 0.72 9.4 0.2 3.1 2 1 1 3 3 3 0 60Kd inner membrane protein SH PF01445.12 KFP02279.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.9 3 0 0 3 3 3 0 Viral small hydrophobic protein YajC PF02699.10 KFP02279.1 - 0.35 10.5 0.0 0.35 10.5 0.0 2.5 3 0 0 3 3 3 0 Preprotein translocase subunit DUF4363 PF14276.1 KFP02279.1 - 1.2 8.8 7.0 4.3 7.0 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Sigma_reg_N PF13800.1 KFP02279.1 - 1.7 8.7 0.0 1.7 8.7 0.0 4.0 4 1 1 5 5 5 0 Sigma factor regulator N-terminal RRM_6 PF14259.1 KFP02280.1 - 1.8e-06 27.7 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP02280.1 - 0.0029 17.1 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3456 PF11938.3 KFP02281.1 - 0.0033 17.4 0.3 0.0035 17.3 0.2 1.0 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SapB_2 PF03489.12 KFP02281.1 - 0.068 13.2 0.1 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Saposin-like type B, region 2 INSIG PF07281.7 KFP02282.1 - 1.2e-56 191.1 0.8 1.3e-56 191.0 0.6 1.0 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) 7tm_1 PF00001.16 KFP02283.1 - 1.1e-77 260.7 9.6 1.1e-77 260.7 6.7 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF3278 PF11683.3 KFP02283.1 - 2.6 8.0 6.0 1.8 8.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) DUF3135 PF11333.3 KFP02284.1 - 0.031 14.4 0.0 0.056 13.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) PTCB-BRCT PF12738.2 KFP02285.1 - 1.7e-56 187.9 1.7 6.8e-21 73.8 0.0 5.0 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.21 KFP02285.1 - 9.7e-54 179.4 0.5 7.4e-12 45.2 0.0 6.2 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain DPPIV_N PF00930.16 KFP02286.1 - 3.1e-112 374.6 0.3 4.7e-112 374.0 0.2 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFP02286.1 - 5.5e-36 123.7 0.1 9.2e-36 123.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.7 KFP02286.1 - 2.4e-06 27.0 0.3 0.015 14.9 0.0 3.2 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.13 KFP02286.1 - 8.3e-05 21.9 1.4 0.00012 21.3 0.3 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFP02286.1 - 0.0024 17.6 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family A_deaminase PF00962.17 KFP02287.1 - 2.1e-58 197.8 0.0 3.3e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KFP02287.1 - 2.9e-22 78.4 0.0 6.4e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Hydrolase_like PF13242.1 KFP02288.1 - 2.4e-07 30.3 0.0 7.2e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KFP02288.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SEFIR PF08357.6 KFP02289.1 - 9.2e-43 145.8 0.7 1.7e-42 144.9 0.0 1.8 2 0 0 2 2 2 1 SEFIR domain DCP1 PF06058.8 KFP02290.1 - 2.2e-34 118.1 0.0 4.7e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Dcp1-like decapping family wnt PF00110.14 KFP02291.1 - 2.9e-120 401.1 23.8 3.2e-120 400.9 16.5 1.0 1 0 0 1 1 1 1 wnt family LRR_6 PF13516.1 KFP02292.1 - 3.9e-21 72.6 42.2 0.037 14.0 0.1 11.9 12 0 0 12 12 12 9 Leucine Rich repeat LRR_4 PF12799.2 KFP02292.1 - 7.2e-16 57.4 20.2 0.0063 16.1 0.8 7.3 2 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP02292.1 - 1.6e-13 48.6 26.8 1.2 9.4 0.0 10.9 9 2 0 9 9 9 4 Leucine Rich Repeat LRR_8 PF13855.1 KFP02292.1 - 1.5e-09 37.4 29.3 0.023 14.4 3.2 6.2 2 2 5 7 7 7 7 Leucine rich repeat LRR_7 PF13504.1 KFP02292.1 - 0.00075 19.2 37.4 16 6.2 0.1 11.3 11 1 1 12 12 12 1 Leucine rich repeat Ste50p-SAM PF09235.5 KFP02292.1 - 0.0022 17.9 4.5 0.21 11.6 0.2 4.4 4 1 1 5 5 5 1 Ste50p, sterile alpha motif LRR_2 PF07723.8 KFP02292.1 - 0.0042 17.5 12.6 2.6 8.6 0.0 6.7 6 0 0 6 6 6 1 Leucine Rich Repeat Bac_DnaA_C PF08299.6 KFP02292.1 - 0.058 13.2 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix Antiterm PF03589.8 KFP02292.1 - 0.15 12.2 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Antitermination protein Cast PF10174.4 KFP02293.1 - 1.1e-264 880.2 162.0 1.3e-264 880.0 112.3 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 KFP02293.1 - 0.00054 19.8 27.3 0.0015 18.4 6.9 9.5 1 1 8 9 9 9 3 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KFP02293.1 - 0.00065 18.3 28.1 0.00065 18.3 19.5 4.9 1 1 4 5 5 5 1 AAA domain DUF869 PF05911.6 KFP02293.1 - 0.0021 16.4 18.3 0.0021 16.4 12.7 5.3 1 1 4 5 5 5 2 Plant protein of unknown function (DUF869) IncA PF04156.9 KFP02293.1 - 0.84 9.2 157.1 0.018 14.6 13.5 8.1 1 1 5 6 6 6 0 IncA protein Reo_sigmaC PF04582.7 KFP02293.1 - 1.8 7.6 47.5 0.054 12.6 2.1 5.7 2 1 4 7 7 7 0 Reovirus sigma C capsid protein Ninjurin PF04923.7 KFP02294.1 - 2.7e-33 113.8 8.4 2.9e-33 113.6 5.8 1.0 1 0 0 1 1 1 1 Ninjurin DUF1418 PF07214.7 KFP02294.1 - 0.038 13.6 3.0 0.062 12.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) RebB PF11747.3 KFP02294.1 - 0.25 11.2 1.1 0.4 10.5 0.7 1.6 1 1 0 1 1 1 0 Killing trait Ninjurin PF04923.7 KFP02295.1 - 2.7e-33 113.8 8.4 2.9e-33 113.6 5.8 1.0 1 0 0 1 1 1 1 Ninjurin DUF1418 PF07214.7 KFP02295.1 - 0.038 13.6 3.0 0.062 12.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) RebB PF11747.3 KFP02295.1 - 0.25 11.2 1.1 0.4 10.5 0.7 1.6 1 1 0 1 1 1 0 Killing trait PA14 PF07691.7 KFP02296.1 - 2.5e-23 82.3 0.1 4.4e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 PA14 domain CHGN PF05679.11 KFP02296.1 - 2e-15 56.5 0.0 1.3e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 KFP02296.1 - 4.2e-12 45.3 0.9 8.9e-12 44.3 0.6 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP02296.1 - 0.0033 16.5 0.4 0.45 9.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 SNF PF00209.13 KFP02297.1 - 7.8e-246 816.5 35.4 9e-246 816.3 24.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF3671 PF12420.3 KFP02297.1 - 6.3 6.8 16.8 0.12 12.3 0.5 3.9 3 2 0 3 3 3 0 Protein of unknown function SNF PF00209.13 KFP02298.1 - 1e-244 812.8 36.6 1.2e-244 812.6 25.4 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SNF PF00209.13 KFP02299.1 - 6.4e-229 760.7 41.2 7.4e-229 760.5 28.6 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family TM231 PF10149.4 KFP02299.1 - 0.012 14.6 1.4 0.024 13.6 1.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 231 Sec7 PF01369.15 KFP02300.1 - 5.4e-60 202.3 0.0 1.4e-59 200.9 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain IQ PF00612.22 KFP02300.1 - 0.056 13.0 1.3 0.18 11.5 0.2 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif WASH_WAHD PF11945.3 KFP02301.1 - 3.9e-148 492.5 0.3 5.5e-148 492.0 0.2 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex Helicase_C_2 PF13307.1 KFP02302.1 - 9.2e-57 191.6 0.4 5e-56 189.2 0.0 2.6 4 0 0 4 4 4 1 Helicase C-terminal domain DEAD_2 PF06733.10 KFP02302.1 - 5.1e-51 172.5 0.6 1.1e-50 171.3 0.4 1.6 1 0 0 1 1 1 1 DEAD_2 SNF2_N PF00176.18 KFP02302.1 - 0.035 12.8 1.1 0.27 10.0 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain zf-H2C2_2 PF13465.1 KFP02303.1 - 9.5e-53 174.0 45.7 2.5e-11 43.2 0.2 6.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFP02303.1 - 6.4e-45 148.8 50.7 8.6e-08 32.0 1.5 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP02303.1 - 2.7e-28 96.1 45.9 3.1e-05 23.9 0.1 7.1 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP02303.1 - 5.4e-23 80.1 40.0 2e-05 24.3 0.1 6.7 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP02303.1 - 3e-14 52.6 28.3 0.0021 18.1 0.1 6.7 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.1 KFP02303.1 - 1.2e-08 34.5 8.1 2.2 8.1 0.0 6.0 6 0 0 6 6 6 1 Prokaryotic RING finger family 1 XPA_N PF01286.13 KFP02303.1 - 1.8e-07 30.7 24.1 0.03 14.0 0.3 6.1 6 0 0 6 6 6 2 XPA protein N-terminal zf-met PF12874.2 KFP02303.1 - 2.1e-07 30.8 38.6 0.29 11.3 0.1 7.0 7 0 0 7 7 7 5 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KFP02303.1 - 4.4e-07 29.7 28.4 0.14 12.1 3.1 5.9 4 2 1 5 5 5 3 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFP02303.1 - 4.5e-05 23.1 31.0 0.13 12.1 0.2 5.3 4 1 1 5 5 5 2 Transposase zinc-ribbon domain LIM PF00412.17 KFP02303.1 - 0.0001 22.2 20.6 0.018 15.1 2.9 4.5 2 2 2 4 4 4 2 LIM domain C1_4 PF07975.7 KFP02303.1 - 0.00074 19.4 24.9 0.34 10.9 5.0 5.1 1 1 5 6 6 6 2 TFIIH C1-like domain DNA_RNApol_7kD PF03604.8 KFP02303.1 - 0.004 16.5 18.8 3.9 7.0 0.1 5.9 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-AN1 PF01428.11 KFP02303.1 - 0.0061 16.4 22.7 7.2 6.5 0.2 6.2 6 0 0 6 6 6 0 AN1-like Zinc finger Yippee-Mis18 PF03226.9 KFP02303.1 - 0.0061 16.5 18.6 3.2 7.8 0.0 4.9 3 2 1 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Di19 PF05605.7 KFP02303.1 - 0.0082 16.2 1.6 0.0082 16.2 1.1 4.5 1 1 5 6 6 6 1 Drought induced 19 protein (Di19), zinc-binding GF_recep_IV PF14843.1 KFP02303.1 - 0.013 15.1 20.1 0.03 13.9 5.3 2.2 1 1 1 2 2 2 0 Growth factor receptor domain IV TFIIS_C PF01096.13 KFP02303.1 - 0.014 15.0 26.1 0.88 9.2 0.2 6.0 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) GAGA PF09237.6 KFP02303.1 - 0.018 14.6 14.8 0.98 9.0 0.0 4.3 1 1 3 5 5 5 0 GAGA factor zf-BED PF02892.10 KFP02303.1 - 0.019 14.7 35.0 2.4 7.9 1.1 6.2 1 1 5 6 6 6 0 BED zinc finger Elf1 PF05129.8 KFP02303.1 - 0.023 14.4 20.4 0.46 10.2 1.2 3.5 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like CpXC PF14353.1 KFP02303.1 - 0.024 14.6 21.1 3.8 7.4 2.6 5.7 3 2 2 5 5 5 0 CpXC protein GATA PF00320.22 KFP02303.1 - 0.035 13.4 8.8 4.5 6.6 0.0 4.2 3 1 1 4 4 4 0 GATA zinc finger Baculo_IE-1 PF05290.6 KFP02303.1 - 0.035 13.8 8.5 6 6.6 0.1 4.0 1 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_2 PF12756.2 KFP02303.1 - 0.048 13.7 28.2 0.33 11.0 0.3 5.4 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) BolA PF01722.13 KFP02303.1 - 0.076 12.9 14.0 7.2 6.6 0.0 4.1 2 1 1 3 3 3 0 BolA-like protein PHF5 PF03660.9 KFP02303.1 - 0.12 12.4 11.9 2.8 8.0 2.2 3.3 1 1 2 3 3 3 0 PHF5-like protein MBD PF01429.14 KFP02303.1 - 0.13 11.8 2.1 5.8 6.5 1.5 3.4 1 1 0 1 1 1 0 Methyl-CpG binding domain YhfH PF14149.1 KFP02303.1 - 0.16 11.7 18.7 4.2 7.2 0.2 5.1 5 0 0 5 5 5 0 YhfH-like protein DUF2072 PF09845.4 KFP02303.1 - 0.16 11.8 23.7 0.54 10.1 0.2 5.4 3 2 3 6 6 6 0 Zn-ribbon containing protein (DUF2072) C1_3 PF07649.7 KFP02303.1 - 0.24 11.4 14.2 12 6.0 0.0 5.8 6 0 0 6 6 6 0 C1-like domain zf-LYAR PF08790.6 KFP02303.1 - 0.31 10.7 20.8 5 6.9 0.1 6.0 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger zf-RING_3 PF14369.1 KFP02303.1 - 0.35 10.9 20.0 1.1 9.3 0.0 5.8 5 1 1 6 6 6 0 zinc-finger RRN7 PF11781.3 KFP02303.1 - 0.42 10.1 16.1 14 5.2 0.1 5.4 6 0 0 6 6 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 KFP02303.1 - 0.6 9.8 0.1 0.6 9.8 0.1 5.8 6 0 0 6 6 5 0 zinc-finger of a C2HC-type zf-ISL3 PF14690.1 KFP02303.1 - 0.63 10.1 22.9 10 6.2 0.3 6.1 5 1 1 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2688 PF10892.3 KFP02303.1 - 0.71 9.5 17.1 1.6 8.4 0.1 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF2688) Zn_ribbon_recom PF13408.1 KFP02303.1 - 0.88 9.8 21.4 2.8 8.2 1.0 4.7 2 2 2 4 4 4 0 Recombinase zinc beta ribbon domain Mut7-C PF01927.11 KFP02303.1 - 0.94 9.4 19.1 9.7 6.1 3.1 3.8 1 1 1 2 2 2 0 Mut7-C RNAse domain UPF0547 PF10571.4 KFP02303.1 - 0.98 9.1 19.9 6.7 6.5 0.1 5.3 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 FYDLN_acid PF09538.5 KFP02303.1 - 1.3 9.6 15.4 7.8 7.1 1.2 5.1 1 1 4 5 5 5 0 Protein of unknown function (FYDLN_acid) DUF899 PF05988.7 KFP02303.1 - 2.1 7.7 6.0 4.6 6.6 0.0 3.0 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF899) zinc-ribbons_6 PF07191.7 KFP02303.1 - 2.1 8.1 23.7 5.6 6.8 0.3 5.6 2 2 2 5 5 5 0 zinc-ribbons HypA PF01155.14 KFP02303.1 - 2.2 8.0 21.9 2.2 7.9 0.6 3.5 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 KFP02303.1 - 4.8 6.9 26.7 8.6 6.1 4.9 4.5 2 2 1 3 3 3 0 zinc-RING finger domain zf-trcl PF13451.1 KFP02303.1 - 4.8 6.8 21.2 15 5.2 0.1 5.7 6 0 0 6 6 6 0 Probable zinc-binding domain HNH PF01844.18 KFP02303.1 - 5.9 6.8 25.6 8.4 6.3 0.2 6.4 7 0 0 7 7 7 0 HNH endonuclease zf-RING_2 PF13639.1 KFP02303.1 - 7.1 6.5 24.6 1.5e+02 2.3 6.4 3.8 1 1 1 2 2 2 0 Ring finger domain A2L_zn_ribbon PF08792.5 KFP02303.1 - 7.2 6.1 28.8 0.29 10.6 0.2 5.5 6 0 0 6 6 6 0 A2L zinc ribbon domain PBP_sp32 PF07222.7 KFP02304.1 - 8e-31 107.0 0.5 8.5e-31 106.9 0.3 1.0 1 0 0 1 1 1 1 Proacrosin binding protein sp32 DUF640 PF04852.7 KFP02304.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF640) IBN_N PF03810.14 KFP02305.1 - 1.2e-21 76.4 0.2 3.9e-18 65.1 0.0 4.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 KFP02305.1 - 1.9e-09 36.5 4.2 1.9e-09 36.5 2.9 2.9 2 1 0 3 3 3 1 Cse1 PPP4R2 PF09184.6 KFP02305.1 - 0.014 14.9 0.1 0.014 14.9 0.0 3.1 3 0 0 3 3 3 0 PPP4R2 DUF1539 PF07560.6 KFP02305.1 - 0.023 14.5 3.9 0.19 11.6 0.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) HEAT_2 PF13646.1 KFP02305.1 - 0.038 14.2 0.0 12 6.2 0.0 3.8 3 0 0 3 3 3 0 HEAT repeats Aida_N PF08910.5 KFP02305.1 - 0.046 13.9 0.9 0.22 11.7 0.1 2.6 2 0 0 2 2 2 0 Aida N-terminus Xpo1 PF08389.7 KFP02305.1 - 0.21 11.4 13.4 0.11 12.4 0.5 4.4 4 1 0 4 4 4 0 Exportin 1-like protein TT_ORF2 PF02957.10 KFP02305.1 - 1.7 9.3 8.6 3.6 8.2 5.9 1.5 1 0 0 1 1 1 0 TT viral ORF2 Caprin-1_C PF12287.3 KFP02306.1 - 1.9e-37 129.3 26.4 3.7e-37 128.4 18.3 1.5 1 0 0 1 1 1 1 Cytoplasmic activation/proliferation-associated protein-1 C term C1q PF00386.16 KFP02306.1 - 1.2e-31 109.3 0.0 2.4e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 C1q domain DUF1460 PF07313.7 KFP02306.1 - 0.075 12.2 0.3 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) FAM60A PF15396.1 KFP02307.1 - 2e-88 295.7 11.1 2.3e-88 295.4 7.7 1.0 1 0 0 1 1 1 1 Protein Family FAM60A DUF2706 PF10913.3 KFP02307.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2706) DENN PF02141.16 KFP02308.1 - 1.8e-62 210.3 6.0 4.4e-62 209.0 2.7 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain RUN PF02759.14 KFP02308.1 - 9e-41 138.7 4.8 6.5e-20 71.2 2.1 3.2 3 0 0 3 3 3 2 RUN domain uDENN PF03456.13 KFP02308.1 - 1.8e-20 72.6 0.2 1.1e-19 70.1 0.0 2.5 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 KFP02308.1 - 3.2e-19 68.7 2.6 3.2e-19 68.7 1.8 3.7 4 1 1 5 5 5 1 dDENN domain PLAT PF01477.18 KFP02308.1 - 5.2e-14 52.5 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain PrmA PF06325.8 KFP02309.1 - 1.1e-10 41.1 0.1 1.6e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KFP02309.1 - 2.6e-09 36.7 0.0 6.9e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFP02309.1 - 2.7e-05 24.1 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP02309.1 - 0.00059 20.3 0.1 0.0013 19.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFP02309.1 - 0.0032 17.0 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 KFP02309.1 - 0.0048 16.2 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KFP02309.1 - 0.058 13.1 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KFP02309.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.14 KFP02309.1 - 0.18 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LRR_6 PF13516.1 KFP02310.1 - 4.1e-13 47.9 3.2 0.057 13.5 0.0 6.4 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.2 KFP02310.1 - 3.9e-07 29.5 1.3 0.00032 20.2 0.0 4.3 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP02310.1 - 0.03 14.0 6.2 0.97 9.2 0.4 4.4 3 2 2 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 KFP02310.1 - 0.033 14.1 8.2 3.4 8.0 0.3 5.6 4 3 1 5 5 5 0 Leucine Rich Repeat Pentapeptide_3 PF13576.1 KFP02310.1 - 0.065 13.1 1.2 16 5.4 0.1 3.8 4 1 0 4 4 4 0 Pentapeptide repeats (9 copies) Adeno_E4_34 PF04528.8 KFP02310.1 - 1.5 8.4 7.7 0.08 12.5 0.4 2.3 1 1 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region DUF4617 PF15395.1 KFP02311.1 - 2.6e-269 896.6 114.7 2.6e-269 896.6 79.5 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4617) BicD PF09730.4 KFP02312.1 - 0 1111.5 69.0 0 1111.5 47.8 2.0 2 0 0 2 2 2 1 Microtubule-associated protein Bicaudal-D HALZ PF02183.13 KFP02312.1 - 0.0006 19.4 1.8 0.0006 19.4 1.2 9.8 10 2 1 11 11 11 3 Homeobox associated leucine zipper DUF869 PF05911.6 KFP02312.1 - 0.00082 17.7 79.2 0.0033 15.7 7.1 4.7 2 1 2 4 4 4 2 Plant protein of unknown function (DUF869) DUF1759 PF03564.10 KFP02312.1 - 0.0013 18.5 7.0 0.0013 18.5 4.9 6.1 4 1 1 6 6 6 1 Protein of unknown function (DUF1759) ADIP PF11559.3 KFP02312.1 - 0.0092 15.8 6.1 0.0092 15.8 4.2 7.4 4 2 4 8 8 8 2 Afadin- and alpha -actinin-Binding ApoO PF09769.4 KFP02312.1 - 0.051 13.2 8.4 0.95 9.1 0.1 4.0 3 1 0 3 3 3 0 Apolipoprotein O RhoGEF PF00621.15 KFP02313.1 - 6.1e-48 163.0 0.6 6.1e-48 163.0 0.4 1.7 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFP02313.1 - 8.7e-23 80.5 0.5 9.5e-13 48.2 0.0 2.8 2 0 0 2 2 2 2 PH domain FYVE PF01363.16 KFP02313.1 - 1.9e-18 66.1 11.2 5.1e-18 64.7 7.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_11 PF15413.1 KFP02313.1 - 2e-06 28.0 0.3 0.073 13.3 0.1 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.1 KFP02313.1 - 0.0012 18.9 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain FYVE_2 PF02318.11 KFP02313.1 - 0.0012 18.6 12.1 0.0049 16.7 8.1 2.4 1 1 1 2 2 2 1 FYVE-type zinc finger Presenilin PF01080.12 KFP02313.1 - 0.012 14.4 1.7 0.023 13.5 1.2 1.4 1 0 0 1 1 1 0 Presenilin zf-RING_5 PF14634.1 KFP02313.1 - 0.11 12.1 12.9 0.28 10.9 8.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PH_5 PF15405.1 KFP02313.1 - 0.18 11.7 3.2 3.8 7.4 0.0 3.2 2 1 1 3 3 3 0 Pleckstrin homology domain IBR PF01485.16 KFP02313.1 - 0.23 11.3 12.4 0.048 13.5 5.7 2.1 1 1 0 1 1 1 0 IBR domain zf-C3HC4_2 PF13923.1 KFP02313.1 - 9 6.4 11.7 40 4.3 8.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dynamin_M PF01031.15 KFP02314.1 - 1.1e-100 336.2 0.1 2.9e-100 334.8 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFP02314.1 - 2.3e-50 170.6 0.6 9.4e-50 168.7 0.1 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KFP02314.1 - 1.3e-32 111.5 2.8 4.6e-32 109.7 1.9 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain LRR_8 PF13855.1 KFP02315.1 - 2.7e-40 135.9 32.1 5.6e-14 51.6 7.3 3.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KFP02315.1 - 1.9e-19 68.8 14.6 1.9e-05 24.1 3.9 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP02315.1 - 7.5e-16 55.7 15.5 0.01 15.7 0.0 7.9 8 0 0 8 8 7 5 Leucine Rich Repeat I-set PF07679.11 KFP02315.1 - 1.4e-15 56.9 0.0 2.8e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.1 KFP02315.1 - 5.5e-15 55.2 0.0 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) Ig_2 PF13895.1 KFP02315.1 - 7.6e-08 32.3 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP02315.1 - 2.5e-07 31.0 0.0 6.2e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 KFP02315.1 - 7.3e-06 25.6 2.1 0.0014 18.2 0.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat ig PF00047.20 KFP02315.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 KFP02315.1 - 9.1e-05 22.5 0.1 0.00027 21.0 0.0 1.8 2 0 0 2 2 1 1 Fibronectin type III domain LRR_7 PF13504.1 KFP02315.1 - 0.00011 21.8 23.9 0.41 11.0 0.0 7.6 8 0 0 8 8 6 2 Leucine rich repeat LRR_6 PF13516.1 KFP02315.1 - 0.0086 16.0 21.4 3.1 8.1 0.0 6.7 8 0 0 8 8 7 2 Leucine Rich repeat V-set PF07686.12 KFP02315.1 - 0.012 15.4 0.0 0.067 13.0 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP02315.1 - 0.02 14.7 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF240 PF03086.9 KFP02315.1 - 0.15 11.7 4.9 0.19 11.3 2.6 1.7 1 1 1 2 2 2 0 MG032/MG096/MG288 family 2 P12 PF12669.2 KFP02315.1 - 0.82 9.9 3.4 2.3 8.5 2.3 1.7 1 0 0 1 1 1 0 Virus attachment protein p12 family LSR PF05624.9 KFP02315.1 - 1.1 9.0 11.9 0.056 13.1 1.6 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) PDEase_I PF00233.14 KFP02316.1 - 5.5e-33 114.6 2.9 5.9e-33 114.5 2.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Neuro_bHLH PF12533.3 KFP02317.1 - 1.2e-18 68.0 0.2 2.4e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Neuronal helix-loop-helix transcription factor HLH PF00010.21 KFP02317.1 - 5.1e-16 58.1 0.9 5.1e-16 58.1 0.6 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nucleoplasmin PF03066.10 KFP02317.1 - 0.036 13.5 3.9 0.059 12.8 2.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2890 PF11081.3 KFP02317.1 - 0.041 13.9 4.3 0.052 13.6 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop53 PF07767.6 KFP02317.1 - 0.053 12.4 8.3 0.065 12.2 5.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM177 PF14774.1 KFP02317.1 - 0.12 12.3 2.5 0.22 11.4 1.8 1.4 1 0 0 1 1 1 0 FAM177 family Myc_N PF01056.13 KFP02317.1 - 0.21 10.7 3.7 0.29 10.2 2.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region FadA PF09403.5 KFP02317.1 - 0.23 11.5 3.0 0.32 11.0 2.1 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Tom37_C PF11801.3 KFP02317.1 - 0.28 11.0 2.5 0.46 10.3 1.8 1.4 1 1 0 1 1 1 0 Tom37 C-terminal domain CDC45 PF02724.9 KFP02317.1 - 0.5 8.3 2.7 0.54 8.2 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 KFP02317.1 - 0.78 9.9 6.2 1.8 8.7 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Spt5_N PF11942.3 KFP02317.1 - 1.2 9.8 11.5 1.9 9.1 7.9 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SLX9 PF15341.1 KFP02317.1 - 1.2 9.5 9.4 3.2 8.1 6.6 1.7 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Ribosomal_60s PF00428.14 KFP02317.1 - 7.8 6.9 11.2 49 4.4 7.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein XendoU PF09412.5 KFP02318.1 - 1.4e-91 306.2 0.1 1.6e-91 306.0 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU Somatomedin_B PF01033.12 KFP02318.1 - 6.1e-08 32.5 14.6 1e-07 31.8 10.1 1.3 1 0 0 1 1 1 1 Somatomedin B domain EndoU_bacteria PF14436.1 KFP02318.1 - 0.0011 18.8 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial EndoU nuclease PDZ PF00595.19 KFP02321.1 - 2.5e-20 72.4 0.2 1.7e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP02321.1 - 7.2e-08 32.2 0.0 2.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 KFP02321.1 - 0.0039 16.9 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Glyco_transf_8 PF01501.15 KFP02322.1 - 8.8e-11 41.6 1.1 1.5e-10 40.8 0.8 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Ribosomal_S25 PF03297.10 KFP02323.1 - 0.08 12.9 3.1 0.14 12.2 2.1 1.4 1 0 0 1 1 1 0 S25 ribosomal protein MOR2-PAG1_N PF14222.1 KFP02323.1 - 0.46 9.1 4.4 0.52 8.9 3.1 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal LMBR1 PF04791.11 KFP02323.1 - 0.81 8.2 4.5 0.96 7.9 3.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Red1 PF07964.6 KFP02323.1 - 1 7.4 9.8 1.2 7.2 6.8 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Macoilin PF09726.4 KFP02323.1 - 5.6 5.1 11.8 6 5.0 8.2 1.0 1 0 0 1 1 1 0 Transmembrane protein CPSF100_C PF13299.1 KFP02323.1 - 7.6 6.7 8.5 4.3 7.5 4.5 1.6 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RAP1 PF07218.6 KFP02323.1 - 8.6 4.3 11.8 9.7 4.1 8.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RRM_1 PF00076.17 KFP02324.1 - 2.3e-22 78.4 0.2 3.8e-22 77.7 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02324.1 - 5.1e-19 68.0 0.1 8.3e-19 67.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP02324.1 - 4.5e-14 52.0 0.2 7.3e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 KFP02324.1 - 0.0001 22.0 1.6 0.00018 21.2 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KFP02324.1 - 0.018 14.7 0.8 0.035 13.8 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Limkain-b1 PF11608.3 KFP02324.1 - 0.019 14.6 0.3 0.084 12.6 0.2 2.1 1 1 0 1 1 1 0 Limkain b1 SET_assoc PF11767.3 KFP02324.1 - 0.071 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated CDC27 PF09507.5 KFP02324.1 - 0.37 9.9 12.4 0.55 9.4 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PET PF06297.9 KFP02325.1 - 3.1e-44 148.9 0.1 7.1e-44 147.7 0.1 1.7 1 0 0 1 1 1 1 PET Domain LIM PF00412.17 KFP02325.1 - 2.7e-25 88.1 40.0 9.9e-10 38.3 2.1 3.6 3 0 0 3 3 3 3 LIM domain Vasculin PF15337.1 KFP02325.1 - 0.0025 18.2 1.8 0.0069 16.8 0.0 2.5 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 Pkinase PF00069.20 KFP02326.1 - 5.7e-54 182.9 0.0 8.1e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02326.1 - 3.5e-49 167.2 0.0 6.3e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Death PF00531.17 KFP02326.1 - 0.0013 18.4 0.0 0.0036 17.0 0.0 1.7 2 0 0 2 2 2 1 Death domain Focal_AT PF03623.8 KFP02326.1 - 0.072 12.5 0.2 0.21 11.0 0.1 1.7 2 0 0 2 2 2 0 Focal adhesion targeting region Cofilin_ADF PF00241.15 KFP02327.1 - 8.3e-25 87.1 0.0 1.9e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TusA PF01206.12 KFP02327.1 - 0.11 12.1 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 Sulfurtransferase TusA TMEM117 PF15113.1 KFP02328.1 - 1.1e-242 804.9 27.0 1.3e-242 804.6 18.7 1.0 1 0 0 1 1 1 1 TMEM117 protein family 7tm_1 PF00001.16 KFP02329.1 - 4.4e-35 121.0 23.5 4.4e-35 121.0 16.3 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PgaD PF13994.1 KFP02329.1 - 8.4 5.8 15.4 0.36 10.3 1.5 2.9 2 2 0 2 2 2 0 PgaD-like protein EGF_CA PF07645.10 KFP02330.1 - 1.4e-29 101.7 63.9 6.2e-12 45.3 4.6 11.0 9 2 1 10 10 8 5 Calcium-binding EGF domain VWC PF00093.13 KFP02330.1 - 2.1e-18 66.1 63.6 2.4e-10 40.3 10.0 10.3 6 1 3 9 9 6 4 von Willebrand factor type C domain EGF_3 PF12947.2 KFP02330.1 - 1e-14 54.1 36.1 6e-09 35.7 9.8 10.8 11 1 0 11 11 10 4 EGF domain cEGF PF12662.2 KFP02330.1 - 4e-10 39.1 12.6 4.9e-08 32.4 2.4 11.1 10 0 0 10 10 10 5 Complement Clr-like EGF-like Laminin_G_2 PF02210.19 KFP02330.1 - 4e-08 33.3 0.1 6.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 KFP02330.1 - 8e-06 25.7 37.9 0.00055 19.8 7.3 11.1 13 0 0 13 13 11 5 EGF-like domain Laminin_G_3 PF13385.1 KFP02330.1 - 1.2e-05 25.5 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 KFP02330.1 - 0.00021 21.3 0.0 0.00054 19.9 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain EGF_MSP1_1 PF12946.2 KFP02330.1 - 0.00029 20.5 8.4 0.00029 20.5 5.8 8.4 9 0 0 9 9 8 3 MSP1 EGF domain 1 FXa_inhibition PF14670.1 KFP02330.1 - 0.0096 16.0 6.8 0.0096 16.0 4.7 10.7 8 3 3 11 11 9 4 Coagulation Factor Xa inhibitory site hEGF PF12661.2 KFP02330.1 - 0.02 14.9 0.8 0.02 14.9 0.6 11.7 11 0 0 11 11 10 0 Human growth factor-like EGF Hormone_1 PF00103.15 KFP02331.1 - 9.3e-33 113.3 1.5 1e-32 113.2 1.1 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Pet20 PF08692.5 KFP02331.1 - 0.075 12.9 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Mating_N PF12731.2 KFP02331.1 - 0.082 12.7 0.1 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Mating-type protein beta 1 Homeobox PF00046.24 KFP02332.1 - 7.6e-22 76.6 4.7 1.6e-21 75.6 3.3 1.5 1 0 0 1 1 1 1 Homeobox domain DUF2986 PF11661.3 KFP02332.1 - 0.0017 18.6 0.5 0.0017 18.6 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) Homeobox_KN PF05920.6 KFP02332.1 - 0.1 12.3 0.3 0.36 10.5 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain Homez PF11569.3 KFP02332.1 - 0.12 11.4 1.3 0.22 10.6 0.3 1.9 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez ARID PF01388.16 KFP02333.1 - 8e-27 92.9 0.1 7.9e-25 86.5 0.0 2.8 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.10 KFP02333.1 - 8.6e-08 32.2 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain PAT1 PF09770.4 KFP02334.1 - 0.0011 17.3 24.2 0.0011 17.3 16.8 2.4 2 1 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Aa_trans PF01490.13 KFP02335.1 - 2.9e-76 256.5 40.0 3.7e-76 256.2 27.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.16 KFP02335.1 - 0.085 12.3 29.7 0.082 12.4 17.0 3.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Aa_trans PF01490.13 KFP02336.1 - 2.9e-79 266.4 42.7 3.4e-79 266.2 29.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_US9 PF06072.6 KFP02336.1 - 0.5 10.2 0.0 0.5 10.2 0.0 3.1 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 DUF4234 PF14018.1 KFP02336.1 - 3.2 7.5 9.4 0.44 10.3 2.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Aa_trans PF01490.13 KFP02337.1 - 1.6e-82 277.1 34.5 2.8e-46 157.8 9.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF4234 PF14018.1 KFP02337.1 - 3.1 7.5 10.5 0.23 11.2 2.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) Herpes_US9 PF06072.6 KFP02337.1 - 7.1 6.5 6.6 6.6 6.6 0.0 3.6 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 LRR_8 PF13855.1 KFP02338.1 - 7.6e-23 80.0 10.2 9.8e-15 54.0 1.5 3.7 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP02338.1 - 5.9e-14 51.3 27.0 4.7e-07 29.2 1.6 4.2 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP02338.1 - 6.9e-10 37.5 19.8 0.11 12.6 0.1 7.8 7 1 1 8 8 8 3 Leucine Rich Repeat LRR_5 PF13306.1 KFP02338.1 - 7.2e-07 28.9 0.2 1.5e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFP02338.1 - 1e-06 27.9 10.5 0.059 13.5 0.2 6.8 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 KFP02338.1 - 1.6e-06 27.5 12.3 0.29 11.3 0.2 6.6 5 1 1 6 6 6 2 Leucine Rich repeat V-set PF07686.12 KFP02338.1 - 4e-06 26.7 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_9 PF14580.1 KFP02338.1 - 7.2e-05 22.4 0.3 0.0025 17.3 0.1 2.2 1 1 1 2 2 2 1 Leucine-rich repeat I-set PF07679.11 KFP02338.1 - 0.00015 21.5 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP02338.1 - 0.00031 20.7 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFP02338.1 - 0.003 17.6 0.0 0.0071 16.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain LRRNT PF01462.13 KFP02338.1 - 0.0052 16.2 1.8 0.0052 16.2 1.3 3.6 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain Ig_3 PF13927.1 KFP02338.1 - 0.0055 17.1 0.3 0.039 14.4 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Shisa PF13908.1 KFP02338.1 - 0.0062 16.7 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KFP02338.1 - 0.022 13.0 0.3 2.2 6.4 0.2 2.3 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E TPR_11 PF13414.1 KFP02339.1 - 1.6e-45 152.5 19.3 9.6e-18 63.5 1.2 4.4 2 2 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFP02339.1 - 1.5e-36 122.5 23.2 4.4e-06 26.0 0.7 7.0 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 KFP02339.1 - 5.7e-29 97.6 22.5 7.4e-05 22.3 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat RPAP3_C PF13877.1 KFP02339.1 - 1.5e-28 98.6 1.5 4.1e-28 97.1 1.0 1.8 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_16 PF13432.1 KFP02339.1 - 1.2e-16 60.9 9.2 5.3e-05 23.7 1.4 5.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFP02339.1 - 3.5e-15 54.5 7.4 6.2e-05 22.5 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP02339.1 - 4e-14 51.8 0.7 0.011 16.2 0.1 5.0 4 2 0 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFP02339.1 - 9.4e-13 47.8 1.5 0.0013 18.5 0.2 4.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFP02339.1 - 2.7e-10 40.0 13.8 0.16 11.9 0.4 5.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFP02339.1 - 4.6e-10 38.5 22.8 0.029 14.1 0.3 7.3 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFP02339.1 - 8.4e-09 35.6 10.1 0.0087 16.3 0.5 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP02339.1 - 1.2e-08 34.4 20.3 0.032 14.4 0.2 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP02339.1 - 0.0007 19.6 7.1 0.02 15.0 0.1 3.8 2 2 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 KFP02339.1 - 0.001 18.8 8.1 0.15 11.9 0.1 4.4 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KFP02339.1 - 0.0018 18.6 11.0 9.8 6.8 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 KFP02339.1 - 0.017 15.0 0.8 13 5.9 0.0 4.0 3 0 0 3 3 3 0 PPR repeat Fis1_TPR_C PF14853.1 KFP02339.1 - 0.022 14.6 17.3 0.18 11.6 0.1 6.0 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.18 KFP02339.1 - 0.038 12.9 14.4 0.05 12.5 0.5 2.8 1 1 1 2 2 2 0 FAT domain Reprolysin_5 PF13688.1 KFP02339.1 - 0.1 12.4 0.1 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12 RPN7 PF10602.4 KFP02339.1 - 0.13 11.6 0.0 0.13 11.6 0.0 4.1 4 1 1 5 5 5 0 26S proteasome subunit RPN7 MutS_IV PF05190.13 KFP02339.1 - 0.17 12.0 7.6 0.51 10.5 1.9 3.4 3 0 0 3 3 3 0 MutS family domain IV TPR_10 PF13374.1 KFP02339.1 - 0.62 10.0 3.4 50 4.0 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M76 PF09768.4 KFP02340.1 - 5e-60 201.8 6.5 5.7e-60 201.6 4.5 1.0 1 0 0 1 1 1 1 Peptidase M76 family DUF1045 PF06299.7 KFP02340.1 - 0.083 12.5 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Peptidase_M91 PF14891.1 KFP02340.1 - 0.13 12.2 0.2 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Effector protein LRR_8 PF13855.1 KFP02341.1 - 9.4e-68 223.8 47.7 1.2e-14 53.7 0.9 7.5 3 1 4 7 7 7 7 Leucine rich repeat I-set PF07679.11 KFP02341.1 - 2.3e-49 165.1 0.0 1.5e-19 69.6 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain LRR_4 PF12799.2 KFP02341.1 - 2.7e-42 141.7 52.5 1.7e-07 30.7 0.7 9.4 4 2 6 10 10 10 10 Leucine Rich repeats (2 copies) Ig_2 PF13895.1 KFP02341.1 - 3.7e-33 113.4 0.0 2.1e-10 40.5 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain LRR_5 PF13306.1 KFP02341.1 - 4.1e-27 94.4 0.8 1.4e-10 40.9 0.0 4.0 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP02341.1 - 2.4e-24 81.6 40.6 0.012 15.5 0.8 16.4 16 1 0 16 16 16 7 Leucine Rich Repeat Ig_3 PF13927.1 KFP02341.1 - 2.1e-21 76.1 0.0 9.7e-06 26.0 0.0 4.6 3 2 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP02341.1 - 1.2e-17 63.7 0.0 8.4e-07 29.0 0.0 4.3 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP02341.1 - 4.7e-13 49.0 0.1 0.0061 16.4 0.1 4.1 2 1 1 3 3 3 3 Immunoglobulin V-set domain LRR_9 PF14580.1 KFP02341.1 - 5.7e-11 42.2 15.6 0.036 13.6 0.3 5.4 1 1 5 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.1 KFP02341.1 - 3.8e-10 38.7 46.8 0.015 15.3 1.0 14.0 13 2 1 14 14 14 3 Leucine Rich repeat C2-set_2 PF08205.7 KFP02341.1 - 1.4e-08 34.5 0.0 0.0092 15.8 0.0 3.7 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain LRR_7 PF13504.1 KFP02341.1 - 1.9e-06 27.1 47.6 0.76 10.2 0.4 14.4 15 0 0 15 15 14 1 Leucine rich repeat C2-set PF05790.10 KFP02341.1 - 0.027 14.4 0.3 6.4 6.8 0.0 3.9 5 0 0 5 5 5 0 Immunoglobulin C2-set domain MFS_1 PF07690.11 KFP02342.1 - 2.7e-41 141.4 32.5 3.8e-36 124.5 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFP02342.1 - 1.7e-05 24.5 11.0 0.19 11.5 3.1 4.4 3 1 1 4 4 4 2 MFS_1 like family Sugar_tr PF00083.19 KFP02342.1 - 0.00058 18.5 10.7 0.00058 18.5 7.4 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2140 PF09911.4 KFP02342.1 - 0.076 12.1 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) MFS_3 PF05977.8 KFP02342.1 - 0.47 8.5 3.6 0.14 10.2 0.2 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Pardaxin PF07425.6 KFP02342.1 - 1.3 8.4 4.9 0.23 10.8 0.4 2.1 2 0 0 2 2 2 0 Pardaxin dUTPase PF00692.14 KFP02343.1 - 1.7e-14 53.3 0.0 2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVT_1 PF00078.22 KFP02345.1 - 2.7e-18 66.1 0.0 5.9e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 7tm_1 PF00001.16 KFP02346.1 - 1.3e-14 53.9 0.6 1.4e-14 53.8 0.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02346.1 - 0.0026 16.9 0.1 0.0027 16.9 0.1 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Reticulon PF02453.12 KFP02346.1 - 0.017 14.7 0.1 0.02 14.4 0.1 1.1 1 0 0 1 1 1 0 Reticulon Ank_2 PF12796.2 KFP02347.1 - 0.0066 16.7 0.0 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) MFS_1 PF07690.11 KFP02348.1 - 6.9e-38 130.2 29.7 1.3e-25 89.8 12.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP02348.1 - 6.4e-34 117.2 21.9 7e-31 107.2 5.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.1 KFP02348.1 - 3.5e-12 45.9 6.0 6.4e-12 45.1 4.2 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1228 PF06779.9 KFP02348.1 - 0.00068 19.6 2.3 0.00068 19.6 1.6 2.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1228) Pentapeptide_3 PF13576.1 KFP02348.1 - 0.0014 18.4 7.8 0.045 13.6 4.0 2.9 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) MFS_3 PF05977.8 KFP02348.1 - 0.11 10.5 8.2 0.73 7.8 0.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 KFP02349.1 - 1.7e-189 630.3 2.4 2.1e-189 630.0 1.7 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFP02349.1 - 1e-26 93.5 8.3 1e-26 93.5 5.8 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily Kazal_2 PF07648.10 KFP02349.1 - 8.7e-06 25.5 9.3 9.4e-06 25.4 4.3 2.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP02349.1 - 0.0028 17.6 9.3 0.0028 17.6 6.5 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain PUCC PF03209.10 KFP02349.1 - 0.11 11.2 0.1 0.11 11.2 0.1 3.9 4 0 0 4 4 4 0 PUCC protein Glyco_transf_29 PF00777.13 KFP02350.1 - 2.5e-75 253.0 0.0 2.8e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF1180 PF06679.7 KFP02351.1 - 1.4e-20 73.8 1.4 1.4e-20 73.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) SNF2_N PF00176.18 KFP02352.1 - 1.4e-74 250.5 1.1 3.4e-74 249.3 0.8 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KFP02352.1 - 2.7e-32 110.2 6.5 3.8e-19 68.1 0.0 4.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 KFP02352.1 - 2.6e-31 107.8 1.0 2.6e-31 107.8 0.7 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 KFP02352.1 - 1.8e-14 53.3 0.0 5.1e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 KFP02352.1 - 0.0011 18.9 0.0 0.14 12.2 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain RGM_C PF06534.8 KFP02353.1 - 1.1e-74 249.4 0.0 1.7e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) C-terminus RGM_N PF06535.7 KFP02353.1 - 4.9e-68 228.2 0.9 7.2e-68 227.6 0.6 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus PBC PF03792.8 KFP02355.1 - 2.4e-71 239.4 0.1 3.5e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.24 KFP02355.1 - 5.5e-20 70.7 0.9 1.3e-19 69.5 0.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP02355.1 - 4.7e-16 58.2 0.0 2.7e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain DUF1319 PF07028.6 KFP02355.1 - 0.007 16.5 0.3 0.016 15.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) HTH_3 PF01381.17 KFP02355.1 - 0.0074 16.1 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KFP02355.1 - 0.0077 16.2 0.1 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Sec15 PF04091.7 KFP02355.1 - 0.0098 15.2 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Homez PF11569.3 KFP02355.1 - 0.016 14.2 0.0 0.038 13.0 0.0 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.1 KFP02355.1 - 0.023 14.8 0.0 0.068 13.3 0.0 1.8 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.8 KFP02355.1 - 0.045 13.1 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NUC130_3NT PF08158.7 KFP02355.1 - 0.24 11.7 0.9 7.8 6.8 0.0 3.2 3 1 0 3 3 3 0 NUC130/3NT domain LIM PF00412.17 KFP02356.1 - 5.2e-31 106.4 22.9 5.3e-16 58.4 4.7 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFP02356.1 - 8.2e-18 63.7 2.3 1.4e-17 63.0 1.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP02356.1 - 0.00011 21.8 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF164 PF02591.10 KFP02356.1 - 0.03 14.1 0.7 0.03 14.1 0.5 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain DUF4636 PF15468.1 KFP02356.1 - 0.18 11.2 2.9 0.25 10.7 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4636) Hormone_recep PF00104.25 KFP02357.1 - 5.1e-41 140.0 0.0 7.1e-41 139.5 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP02357.1 - 4.1e-32 110.2 15.7 7.1e-32 109.4 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Nuc_recep-AF1 PF11825.3 KFP02357.1 - 8.5e-28 96.4 16.7 8.5e-28 96.4 11.6 1.7 2 0 0 2 2 2 1 Nuclear/hormone receptor activator site AF-1 Sushi PF00084.15 KFP02358.1 - 2e-45 152.9 68.1 1.8e-08 34.5 1.8 7.4 8 0 0 8 8 8 6 Sushi domain (SCR repeat) Lectin_C PF00059.16 KFP02358.1 - 6.5e-19 68.5 7.5 8.9e-19 68.0 3.4 2.6 2 0 0 2 2 2 1 Lectin C-type domain EGF_2 PF07974.8 KFP02358.1 - 9.5e-06 25.6 10.0 9.5e-06 25.6 6.9 4.6 4 0 0 4 4 4 1 EGF-like domain EGF PF00008.22 KFP02358.1 - 0.00044 20.1 10.5 0.00044 20.1 7.2 3.6 3 0 0 3 3 3 1 EGF-like domain hEGF PF12661.2 KFP02358.1 - 0.015 15.3 5.8 0.015 15.3 4.0 5.9 6 0 0 6 6 6 0 Human growth factor-like EGF Ocnus PF05005.10 KFP02359.1 - 4.4e-40 135.9 0.4 4.8e-40 135.7 0.3 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Methyltransf_16 PF10294.4 KFP02360.1 - 7.9e-14 51.4 0.0 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 KFP02360.1 - 1.6e-07 31.0 0.0 0.004 16.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KFP02360.1 - 5.7e-07 30.1 0.0 9.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP02360.1 - 1.8e-06 27.7 0.0 2.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP02360.1 - 2.2e-05 23.8 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KFP02360.1 - 5.8e-05 23.4 0.0 0.23 11.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.8 KFP02360.1 - 0.00031 19.9 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KFP02360.1 - 0.0085 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KFP02360.1 - 0.0092 16.0 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 KFP02361.1 - 3.8e-05 22.9 0.0 0.00039 19.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KFP02361.1 - 0.032 14.3 0.7 13 6.1 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat KAP PF05804.7 KFP02362.1 - 0 1241.0 24.1 0 1240.9 16.7 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.18 KFP02362.1 - 0.00021 20.9 14.4 0.31 10.9 0.1 6.9 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat FPL PF09758.4 KFP02362.1 - 0.075 12.8 7.9 0.031 14.0 2.3 2.7 3 0 0 3 3 3 0 Uncharacterised conserved protein HEAT_2 PF13646.1 KFP02362.1 - 0.72 10.1 4.3 45 4.4 0.0 4.4 5 1 0 5 5 5 0 HEAT repeats Methyltransf_PK PF05891.7 KFP02363.1 - 2.3e-69 233.0 0.0 4.5e-69 232.0 0.0 1.4 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KFP02363.1 - 4.1e-05 24.1 0.0 6.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP02363.1 - 0.0017 18.7 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP02363.1 - 0.0023 18.3 0.0 0.0035 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFP02363.1 - 0.006 15.7 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 KFP02363.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFP02363.1 - 0.066 12.5 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Transcrip_act PF04949.8 KFP02364.1 - 0.00053 19.6 15.8 0.00095 18.8 10.9 1.5 1 1 0 1 1 1 1 Transcriptional activator YscJ_FliF_C PF08345.6 KFP02364.1 - 0.17 11.8 4.6 0.065 13.2 1.2 1.7 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal Homeobox PF00046.24 KFP02365.1 - 1.9e-23 81.8 6.1 3.6e-23 80.9 4.3 1.5 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFP02365.1 - 2.4e-08 33.2 0.0 4.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFP02365.1 - 0.0013 18.3 0.1 0.003 17.2 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain FMO-like PF00743.14 KFP02366.1 - 2.1e-234 778.6 0.0 2.3e-234 778.5 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFP02366.1 - 5.2e-17 62.5 0.0 8.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFP02366.1 - 1.8e-10 41.0 0.0 7.4e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFP02366.1 - 2.5e-09 36.5 0.0 9.6e-08 31.3 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFP02366.1 - 6.4e-07 29.2 0.0 4.7e-06 26.4 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFP02366.1 - 5.5e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFP02366.1 - 0.012 16.0 0.4 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase OLF PF02191.11 KFP02367.1 - 4.3e-87 291.5 0.0 4.9e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Olfactomedin-like domain Glyco_hydro_1 PF00232.13 KFP02368.1 - 7.2e-163 541.9 3.2 8.2e-163 541.8 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF2352 PF09817.4 KFP02369.1 - 8.6e-164 545.9 4.1 1.4e-163 545.2 2.9 1.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2352) PPR PF01535.15 KFP02369.1 - 0.023 14.6 0.1 15 5.8 0.0 3.4 2 0 0 2 2 2 0 PPR repeat WD40 PF00400.27 KFP02370.1 - 1.2e-28 97.8 13.2 5.7e-08 32.3 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CHCH PF06747.8 KFP02371.1 - 0.0016 18.3 8.4 0.0023 17.8 5.8 1.3 1 0 0 1 1 1 1 CHCH domain DB PF01682.14 KFP02371.1 - 0.0076 16.2 0.9 0.0089 16.0 0.6 1.2 1 0 0 1 1 1 1 DB module Cmc1 PF08583.5 KFP02371.1 - 0.03 14.0 5.0 0.49 10.1 0.8 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KFP02371.1 - 0.045 13.7 1.4 0.057 13.4 1.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 KFP02371.1 - 0.1 12.6 2.6 0.14 12.1 1.8 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.3 KFP02371.1 - 0.21 11.7 1.6 5.8 7.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Ribosomal_S10 PF00338.17 KFP02372.1 - 1.8e-13 50.1 0.4 3e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Ras PF00071.17 KFP02373.1 - 1.1e-53 180.8 0.8 1.3e-53 180.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP02373.1 - 7.7e-19 68.3 0.1 1.5e-18 67.4 0.1 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFP02373.1 - 3.3e-12 45.9 0.4 3.6e-12 45.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP02373.1 - 6.5e-06 25.7 0.3 1.2e-05 24.8 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP02373.1 - 0.00013 21.1 0.1 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFP02373.1 - 0.0014 18.6 0.1 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP02373.1 - 0.0055 15.8 0.2 0.0068 15.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFP02373.1 - 0.022 14.0 0.3 0.032 13.4 0.2 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1854 PF08909.6 KFP02373.1 - 0.065 12.8 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) PH PF00169.24 KFP02375.1 - 5e-05 23.4 0.0 7.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP02375.1 - 0.00054 20.1 0.4 0.00074 19.7 0.3 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFP02375.1 - 0.0025 17.8 0.2 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain TCRP1 PF14944.1 KFP02377.1 - 3.5e-94 314.2 41.3 4.1e-94 314.0 28.6 1.1 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 RhoGEF PF00621.15 KFP02378.1 - 3e-44 151.0 3.6 4.9e-44 150.3 2.5 1.4 1 0 0 1 1 1 1 RhoGEF domain BBS2_Mid PF14783.1 KFP02378.1 - 0.0014 18.4 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region UPF0278 PF08745.6 KFP02378.1 - 0.01 15.0 0.2 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 UPF0278 family Herpes_UL14 PF03580.9 KFP02378.1 - 0.041 13.6 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Mnd1 PF03962.10 KFP02378.1 - 0.07 12.7 0.4 9.4 5.8 0.1 2.7 2 0 0 2 2 2 0 Mnd1 family DUF4496 PF14908.1 KFP02378.1 - 0.082 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) Amidohydro_1 PF01979.15 KFP02379.1 - 6.7e-16 58.8 0.0 9.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFP02379.1 - 1.5e-06 28.4 0.0 2.5e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFP02379.1 - 0.00023 20.5 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Pkinase PF00069.20 KFP02380.1 - 1.7e-15 56.8 0.0 3.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Dimer_Tnp_Tn5 PF02281.11 KFP02380.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Transposase Tn5 dimerisation domain Pkinase_Tyr PF07714.12 KFP02380.1 - 0.007 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP02380.1 - 0.025 13.5 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Yae1_N PF09811.4 KFP02381.1 - 9.4e-12 44.2 30.3 1 8.9 21.0 3.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Paralemmin PF03285.10 KFP02382.1 - 2.3e-44 151.9 13.2 3.7e-44 151.2 9.2 1.3 1 1 0 1 1 1 1 Paralemmin AKAP2_C PF15304.1 KFP02383.1 - 5.3e-19 69.0 16.7 5.3e-19 69.0 11.6 2.9 2 1 0 2 2 2 1 A-kinase anchor protein 2 C-terminus RII_binding_1 PF10522.4 KFP02383.1 - 0.023 14.7 0.2 0.1 12.8 0.1 2.2 2 0 0 2 2 2 0 RII binding domain PX PF00787.19 KFP02384.1 - 4e-23 81.3 1.9 7.9e-23 80.4 1.3 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KFP02384.1 - 7.2e-11 41.7 0.7 1.6e-05 24.2 0.0 2.4 2 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.13 KFP02384.1 - 5.7e-08 32.5 0.5 1.4e-07 31.2 0.3 1.8 2 0 0 2 2 2 1 BAR domain BAR_3_WASP_bdg PF10456.4 KFP02384.1 - 0.008 15.4 0.2 0.027 13.7 0.0 1.8 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein DUF842 PF05811.8 KFP02384.1 - 0.48 9.8 3.7 2.4 7.6 0.4 2.3 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Cache_2 PF08269.6 KFP02385.1 - 0.039 13.9 0.1 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Cache domain DUF3504 PF12012.3 KFP02386.1 - 1.1e-15 57.8 0.2 3e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) WIF PF02019.13 KFP02386.1 - 0.098 12.1 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 WIF domain SCP2 PF02036.12 KFP02387.1 - 1.6e-23 82.9 0.1 3.2e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family adh_short PF00106.20 KFP02387.1 - 2.6e-17 63.2 0.0 4.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFP02387.1 - 1.6e-07 31.3 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFP02387.1 - 4.9e-05 23.0 0.2 9.5e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.1 KFP02387.1 - 0.048 13.6 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal DDE_Tnp_4 PF13359.1 KFP02387.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease RRM_5 PF13893.1 KFP02388.1 - 1.2e-41 140.3 1.5 1.9e-13 50.0 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02388.1 - 5.3e-34 116.0 1.9 7.2e-09 35.5 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP02388.1 - 4.1e-31 106.4 0.5 3.4e-09 36.1 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EGF_CA PF07645.10 KFP02389.1 - 9.6e-16 57.4 24.4 1.9e-09 37.3 5.5 4.4 5 0 0 5 5 5 2 Calcium-binding EGF domain Sushi PF00084.15 KFP02389.1 - 1.7e-15 57.1 7.4 8.8e-09 35.5 0.5 5.3 5 0 0 5 5 5 2 Sushi domain (SCR repeat) cEGF PF12662.2 KFP02389.1 - 1e-12 47.4 26.7 1.9e-08 33.7 1.5 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.2 KFP02389.1 - 1.3e-12 47.4 38.2 8.7e-06 25.5 5.2 4.4 4 0 0 4 4 4 3 EGF domain FXa_inhibition PF14670.1 KFP02389.1 - 1.4e-05 25.0 34.8 0.0037 17.3 5.4 4.4 3 1 1 4 4 4 2 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 KFP02389.1 - 0.00029 20.5 27.5 0.0071 16.0 4.8 3.8 3 0 0 3 3 3 2 MSP1 EGF domain 1 fn3 PF00041.16 KFP02389.1 - 0.0038 17.3 0.1 13 6.0 0.0 3.4 3 0 0 3 3 3 1 Fibronectin type III domain Glyco_transf_21 PF13506.1 KFP02391.1 - 2e-55 186.7 0.0 2.9e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KFP02391.1 - 8e-28 97.7 0.0 9.7e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KFP02391.1 - 2.6e-14 53.3 3.5 3.5e-14 52.9 2.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KFP02391.1 - 2.2e-05 24.2 0.0 4.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 KFP02391.1 - 0.023 13.1 0.0 0.038 12.3 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase G-gamma PF00631.17 KFP02392.1 - 2.1e-09 36.9 0.0 2.2e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain SurA_N_3 PF13624.1 KFP02393.1 - 0.0064 16.4 1.3 0.058 13.3 0.1 2.1 2 0 0 2 2 2 1 SurA N-terminal domain AsmA_1 PF13109.1 KFP02393.1 - 0.08 12.2 1.1 0.091 12.0 0.1 1.6 2 0 0 2 2 2 0 AsmA-like C-terminal region SBP_bac_7 PF03480.8 KFP02393.1 - 7.6 5.5 7.3 0.9 8.5 0.5 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Ecm29 PF13001.2 KFP02394.1 - 1.3e-152 508.7 0.4 8.8e-152 506.0 0.2 2.4 3 0 0 3 3 3 1 Proteasome stabiliser HEAT_2 PF13646.1 KFP02394.1 - 3.5e-16 59.2 14.0 0.0057 16.8 0.0 9.4 9 2 0 9 9 9 5 HEAT repeats HEAT PF02985.17 KFP02394.1 - 4.1e-15 54.4 10.8 0.044 13.8 0.0 11.9 14 0 0 14 14 14 4 HEAT repeat HEAT_EZ PF13513.1 KFP02394.1 - 5.8e-13 48.8 18.0 0.68 10.4 0.1 11.9 13 2 1 14 14 14 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFP02394.1 - 8.9e-13 48.4 0.0 0.00071 19.9 0.0 8.3 8 1 1 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFP02394.1 - 0.0051 16.6 7.2 23 4.7 0.0 6.8 8 0 0 8 8 8 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFP02394.1 - 0.044 13.1 11.7 0.084 12.2 0.1 5.4 6 1 1 7 7 7 0 CLASP N terminal ADH_zinc_N PF00107.21 KFP02395.1 - 6.3e-22 77.5 0.0 1.1e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFP02395.1 - 2.8e-08 34.6 0.0 8.3e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thioredoxin PF00085.15 KFP02396.1 - 6.9e-32 109.2 0.9 7.4e-32 109.1 0.6 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFP02396.1 - 9.6e-08 32.2 0.1 1e-06 28.8 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFP02396.1 - 1.8e-07 31.1 0.4 2.8e-07 30.5 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFP02396.1 - 0.00012 21.9 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 KFP02396.1 - 0.00059 19.7 0.1 0.00089 19.2 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin AhpC-TSA PF00578.16 KFP02396.1 - 0.0006 19.5 0.2 0.00079 19.1 0.2 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KFP02396.1 - 0.0021 17.6 0.2 0.0036 16.8 0.1 1.6 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.5 KFP02396.1 - 0.0037 16.8 0.3 0.0049 16.4 0.2 1.3 1 1 0 1 1 1 1 Redoxin DIM1 PF02966.11 KFP02396.1 - 0.0052 16.2 0.1 0.0063 16.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Pkinase_Tyr PF07714.12 KFP02397.1 - 1.8e-94 315.6 0.0 2.4e-94 315.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.11 KFP02397.1 - 2.8e-46 155.2 0.0 4.5e-20 71.3 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Pkinase PF00069.20 KFP02397.1 - 1.7e-42 145.3 0.0 3.7e-42 144.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.1 KFP02397.1 - 2.3e-30 104.5 0.0 6.8e-14 51.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain Kringle PF00051.13 KFP02397.1 - 3.2e-23 81.6 6.4 7.8e-23 80.3 4.4 1.7 1 0 0 1 1 1 1 Kringle domain Ig_3 PF13927.1 KFP02397.1 - 3.8e-22 78.5 4.2 4.8e-09 36.5 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin domain Fz PF01392.17 KFP02397.1 - 2.8e-20 72.8 5.0 5.8e-20 71.7 3.5 1.6 1 0 0 1 1 1 1 Fz domain ig PF00047.20 KFP02397.1 - 1.5e-18 66.6 0.3 1.2e-06 28.5 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP02397.1 - 1.3e-14 54.0 0.0 2.6e-07 30.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP02397.1 - 3.1e-10 39.7 0.2 0.0095 15.8 0.0 3.7 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP02397.1 - 7.8e-06 24.4 2.5 0.051 11.8 0.0 3.6 3 1 1 4 4 4 2 Alphaherpesvirus glycoprotein E Kinase-like PF14531.1 KFP02397.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like IncA PF04156.9 KFP02397.1 - 0.19 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 IncA protein 7tm_1 PF00001.16 KFP02398.1 - 2.5e-40 138.2 24.3 3.3e-40 137.8 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_9_N PF15420.1 KFP02398.1 - 0.24 11.1 13.3 0.091 12.4 6.1 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Herpes_US9 PF06072.6 KFP02398.1 - 5.5 6.9 14.2 15 5.5 0.3 4.4 3 1 1 4 4 4 0 Alphaherpesvirus tegument protein US9 Guanylate_cyc PF00211.15 KFP02400.1 - 3.2e-63 212.4 0.1 3.3e-62 209.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.12 KFP02400.1 - 5.2e-42 143.7 0.0 8.1e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP02400.1 - 5.2e-35 120.8 0.0 9.2e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.9 KFP02400.1 - 3.3e-06 26.4 0.9 5.3e-06 25.8 0.6 1.4 1 0 0 1 1 1 1 Heme NO binding associated zf-C3HC4_2 PF13923.1 KFP02402.1 - 1.8e-09 37.4 8.5 1.8e-09 37.4 5.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP02402.1 - 2.5e-09 36.6 7.1 2.5e-09 36.6 4.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP02402.1 - 3.2e-09 36.4 8.2 3.2e-09 36.4 5.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFP02402.1 - 4.2e-09 35.9 5.4 4.2e-09 35.9 3.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP02402.1 - 1e-06 28.3 8.1 1e-06 28.3 5.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP02402.1 - 3.2e-06 26.9 7.6 1.2e-05 25.0 5.3 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFP02402.1 - 0.00021 21.3 6.6 0.00093 19.2 4.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFP02402.1 - 0.0025 17.5 5.8 0.0086 15.7 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KFP02402.1 - 0.0034 17.1 3.1 0.0083 15.9 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KFP02402.1 - 0.1 12.3 2.1 0.29 10.9 1.4 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 KFP02402.1 - 0.34 10.4 8.1 1 8.9 5.6 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TLV_coat PF00429.14 KFP02403.1 - 0.01 14.3 0.2 0.012 14.1 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Yae1_N PF09811.4 KFP02404.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RRM_1 PF00076.17 KFP02407.1 - 3.1e-67 222.1 0.1 2.7e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02407.1 - 1.3e-38 130.7 0.0 2.2e-13 49.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP02407.1 - 2.9e-29 100.6 0.2 4e-11 42.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP02407.1 - 0.00016 21.4 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_2 PF04059.7 KFP02407.1 - 0.033 14.2 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif 2 RNA_bind PF08675.6 KFP02407.1 - 0.11 12.4 0.0 4.3 7.3 0.0 3.0 3 2 0 3 3 3 0 RNA binding domain Yae1_N PF09811.4 KFP02409.1 - 4.5e-14 51.6 38.3 5.1 6.7 0.2 4.3 2 1 0 2 2 2 2 Essential protein Yae1, N terminal CAAP1 PF15335.1 KFP02410.1 - 1.8e-33 114.5 9.9 3.2e-33 113.7 6.8 1.4 1 0 0 1 1 1 1 Caspase activity and apoptosis inhibitor 1 PUL PF08324.6 KFP02411.1 - 2e-67 226.7 4.0 2.8e-67 226.3 2.7 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KFP02411.1 - 3.8e-43 146.1 0.1 6.9e-43 145.3 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KFP02411.1 - 9.8e-43 142.5 13.0 4e-10 39.1 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat GAGE PF05831.6 KFP02411.1 - 0.12 12.5 0.1 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 GAGE protein FUSC PF04632.7 KFP02412.1 - 1.8 6.8 4.7 4.4 5.6 0.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family LRR_8 PF13855.1 KFP02413.1 - 6.1e-26 89.9 34.0 5.8e-14 51.5 4.2 3.9 2 1 3 5 5 5 3 Leucine rich repeat LRR19-TM PF15176.1 KFP02413.1 - 3.1e-21 74.9 0.0 5.2e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain LRR_4 PF12799.2 KFP02413.1 - 2.5e-09 36.5 21.9 2.6e-05 23.7 2.3 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP02413.1 - 1.8e-06 27.1 18.2 0.25 11.4 0.0 6.0 6 2 0 6 6 6 4 Leucine Rich Repeat LRR_5 PF13306.1 KFP02413.1 - 3.9e-05 23.3 8.3 3.9e-05 23.3 5.7 2.6 3 1 0 3 3 3 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFP02413.1 - 0.0019 18.1 16.5 0.57 10.4 0.3 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.1 KFP02413.1 - 0.048 13.2 2.2 0.094 12.2 1.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 KFP02413.1 - 0.16 12.2 13.6 56 4.6 0.8 6.2 5 1 1 6 6 6 0 Leucine rich repeat Pkinase_Tyr PF07714.12 KFP02414.1 - 2.6e-91 305.2 0.0 3.7e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP02414.1 - 2.1e-47 161.4 0.0 3.6e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ig_Tie2_1 PF10430.4 KFP02414.1 - 1.2e-32 112.1 0.0 2.9e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Tie-2 Ig-like domain 1 fn3 PF00041.16 KFP02414.1 - 5e-30 103.4 4.2 7.7e-12 45.1 0.5 3.5 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.11 KFP02414.1 - 3.1e-06 26.9 0.0 0.00023 20.9 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin I-set domain APH PF01636.18 KFP02414.1 - 0.0011 18.8 0.0 0.12 12.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family hEGF PF12661.2 KFP02414.1 - 0.0012 18.7 31.0 0.0038 17.2 1.9 5.0 4 0 0 4 4 4 2 Human growth factor-like EGF EGF_2 PF07974.8 KFP02414.1 - 0.005 16.9 12.4 0.005 16.9 8.6 5.2 5 0 0 5 5 5 2 EGF-like domain Laminin_EGF PF00053.19 KFP02414.1 - 0.019 14.8 48.4 1.2 9.0 11.9 4.1 2 1 2 4 4 4 0 Laminin EGF-like (Domains III and V) V-set PF07686.12 KFP02414.1 - 0.02 14.8 0.0 0.58 10.0 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin V-set domain DUF1835 PF08874.5 KFP02414.1 - 0.082 12.8 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) EGF PF00008.22 KFP02414.1 - 7.2 6.6 48.9 0.32 11.0 8.1 4.5 4 0 0 4 4 4 0 EGF-like domain Mob1_phocein PF03637.12 KFP02415.1 - 2.2e-80 268.4 0.4 2.5e-80 268.2 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family C9orf72-like PF15019.1 KFP02416.1 - 5.2e-85 284.3 0.0 8.2e-85 283.7 0.0 1.3 1 0 0 1 1 1 1 C9orf72-like protein family LRR_8 PF13855.1 KFP02417.1 - 1.8e-65 216.5 68.5 3.4e-12 45.9 1.3 6.3 2 2 6 8 8 8 8 Leucine rich repeat LRR_5 PF13306.1 KFP02417.1 - 3.9e-25 88.0 0.0 1e-09 38.1 0.0 3.2 2 1 1 3 3 3 3 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFP02417.1 - 1e-22 79.2 32.6 2.3e-06 27.0 0.7 6.9 5 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP02417.1 - 4.1e-17 59.5 32.5 0.73 10.0 0.1 12.4 12 0 0 12 12 12 5 Leucine Rich Repeat I-set PF07679.11 KFP02417.1 - 6.5e-17 61.1 0.0 1.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP02417.1 - 2.9e-07 30.4 0.9 4.3e-07 29.9 0.0 1.7 2 0 0 2 2 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP02417.1 - 3.6e-07 30.5 0.0 3.1e-06 27.6 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP02417.1 - 3.7e-05 23.5 0.0 0.00014 21.7 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin V-set domain LRRNT PF01462.13 KFP02417.1 - 6.6e-05 22.2 2.6 6.6e-05 22.2 1.8 3.1 4 0 0 4 4 4 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 KFP02417.1 - 8.4e-05 22.2 33.4 0.1 12.7 0.1 10.3 10 1 1 11 11 11 2 Leucine Rich repeat ig PF00047.20 KFP02417.1 - 0.0013 18.8 0.1 0.0057 16.7 0.0 2.3 2 1 0 2 2 1 1 Immunoglobulin domain LRR_7 PF13504.1 KFP02417.1 - 0.0024 17.7 40.2 6.4 7.4 0.0 11.3 12 0 0 12 12 11 1 Leucine rich repeat FixQ PF05545.6 KFP02417.1 - 0.22 11.1 0.8 0.51 10.0 0.5 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ LRR_9 PF14580.1 KFP02417.1 - 0.24 10.9 7.6 0.32 10.5 0.8 2.9 2 2 1 3 3 3 0 Leucine-rich repeat TLV_coat PF00429.14 KFP02419.1 - 0.004 15.6 0.1 0.0041 15.6 0.1 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) TipAS PF07739.8 KFP02419.1 - 0.04 14.2 0.0 0.045 14.0 0.0 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Tetraspannin PF00335.15 KFP02420.1 - 3.4e-20 72.2 9.4 4.1e-20 72.0 6.5 1.1 1 0 0 1 1 1 1 Tetraspanin family Dispanin PF04505.7 KFP02420.1 - 0.077 12.5 7.1 1.9 8.0 0.1 3.6 2 1 1 3 3 3 0 Interferon-induced transmembrane protein YfhO PF09586.5 KFP02420.1 - 0.62 8.0 4.2 0.86 7.5 2.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1900 PF08954.6 KFP02421.1 - 4.1e-52 175.2 0.0 1.1e-51 173.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KFP02421.1 - 4.8e-32 109.4 0.1 7.6e-32 108.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KFP02421.1 - 2e-25 87.6 3.2 2.8e-08 33.3 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat HAUS2 PF15003.1 KFP02421.1 - 0.03 13.4 0.5 0.055 12.5 0.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 SGL PF08450.7 KFP02421.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region RabGAP-TBC PF00566.13 KFP02422.1 - 4.6e-52 176.5 1.1 4.6e-52 176.5 0.8 2.5 2 1 1 3 3 3 1 Rab-GTPase-TBC domain PH_11 PF15413.1 KFP02422.1 - 7.2e-05 23.0 0.5 7.2e-05 23.0 0.4 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFP02422.1 - 0.00015 21.8 0.2 0.00042 20.3 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain BLOC1_2 PF10046.4 KFP02422.1 - 1.2 9.3 23.3 0.1 12.7 4.2 3.5 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Y_phosphatase3 PF13350.1 KFP02422.1 - 1.4 9.1 7.8 14 5.8 5.3 2.3 1 1 0 1 1 1 0 Tyrosine phosphatase family CTDII PF01556.13 KFP02423.1 - 2e-23 82.0 0.3 6.7e-18 64.3 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFP02423.1 - 1.8e-13 50.2 20.7 3.9e-13 49.2 14.4 1.6 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 KFP02423.1 - 5.9e-06 25.9 0.1 1.1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.14 KFP02423.1 - 0.016 14.8 8.6 0.62 9.7 0.7 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family WD40 PF00400.27 KFP02424.1 - 5.4e-47 156.0 12.9 5.9e-11 41.8 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KFP02424.1 - 2.6e-10 39.0 1.3 1.7e-06 26.4 0.5 3.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFP02424.1 - 7.9e-05 21.5 1.1 0.1 11.3 0.7 3.6 2 1 0 3 3 3 1 Nup133 N terminal like Hira PF07569.6 KFP02424.1 - 0.00035 19.8 0.2 1.3 8.1 0.0 3.8 3 1 1 4 4 4 1 TUP1-like enhancer of split LisH PF08513.6 KFP02424.1 - 0.015 15.0 0.1 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 LisH PD40 PF07676.7 KFP02424.1 - 0.077 12.6 0.0 3.6 7.3 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_transf_7N PF13733.1 KFP02425.1 - 4.7e-48 162.0 0.0 6.9e-48 161.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFP02425.1 - 2.7e-32 110.0 0.2 5.1e-32 109.1 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP02425.1 - 7.8e-08 31.7 0.1 7.4e-05 21.9 0.0 2.2 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Kazal_1 PF00050.16 KFP02426.1 - 3.8e-16 58.8 5.6 6.9e-15 54.7 3.9 2.0 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFP02426.1 - 6.4e-12 45.2 1.2 6.4e-12 45.2 0.8 1.9 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain XPA_C PF05181.7 KFP02429.1 - 7.2e-29 99.1 1.4 8.3e-29 98.9 1.0 1.0 1 0 0 1 1 1 1 XPA protein C-terminus MIF4G_like_2 PF09090.6 KFP02430.1 - 3.2e-74 249.3 3.3 5.8e-74 248.5 1.6 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.6 KFP02430.1 - 2.3e-57 193.5 3.3 3.3e-54 183.2 1.5 3.7 3 1 0 3 3 3 1 MIF4G like MIF4G PF02854.14 KFP02430.1 - 4.9e-25 88.1 2.5 9.2e-25 87.2 0.0 2.8 3 0 0 3 3 3 1 MIF4G domain Mnd1 PF03962.10 KFP02430.1 - 0.0086 15.7 0.8 0.02 14.5 0.5 1.6 1 0 0 1 1 1 1 Mnd1 family DUF4611 PF15387.1 KFP02430.1 - 0.022 14.8 0.7 0.022 14.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Vfa1 PF08432.5 KFP02430.1 - 0.31 11.0 5.1 0.6 10.1 3.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 KFP02430.1 - 1 9.7 12.5 0.036 14.3 4.3 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FlxA PF14282.1 KFP02430.1 - 3.9 7.4 6.8 1.7 8.5 2.7 1.9 2 0 0 2 2 2 0 FlxA-like protein Rhodanese PF00581.15 KFP02431.1 - 7.2e-10 39.2 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Tropomodulin PF03250.9 KFP02432.1 - 4.5e-43 146.2 7.9 8.3e-42 142.1 5.5 2.4 1 1 0 1 1 1 1 Tropomodulin DAGK_acc PF00609.14 KFP02433.1 - 1.3e-49 168.4 0.0 2.8e-49 167.3 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFP02433.1 - 1.4e-26 92.4 0.0 3e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RA PF00788.18 KFP02433.1 - 6.2e-19 68.2 1.8 6.8e-11 42.5 0.2 3.3 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain C1_1 PF00130.17 KFP02433.1 - 2.7e-15 55.8 40.2 3.6e-12 45.8 4.1 4.0 3 1 1 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KFP02433.1 - 0.0035 17.3 5.3 0.0035 17.3 3.7 4.1 4 1 0 4 4 4 2 C1-like domain zf-met PF12874.2 KFP02433.1 - 2.2 8.5 11.3 2.7 8.3 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Aconitase PF00330.15 KFP02434.1 - 6.6e-136 453.4 0.0 8.3e-136 453.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFP02434.1 - 3e-44 150.2 0.0 9.1e-43 145.5 0.0 2.3 2 0 0 2 2 2 1 Aconitase C-terminal domain RIG-I_C-RD PF11648.3 KFP02435.1 - 2.2e-28 98.5 3.5 2.2e-28 98.5 2.4 2.1 2 0 0 2 2 2 1 C-terminal domain of RIG-I DEAD PF00270.24 KFP02435.1 - 8.2e-19 67.7 0.0 2.8e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFP02435.1 - 5.9e-17 62.0 2.1 1.2e-15 57.8 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFP02435.1 - 8.7e-12 44.7 0.0 2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_10 PF12846.2 KFP02435.1 - 0.00075 19.0 0.1 0.11 11.8 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 KFP02435.1 - 0.0012 19.0 0.0 0.0063 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFP02435.1 - 0.015 14.6 0.0 0.045 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain CYTL1 PF15153.1 KFP02435.1 - 0.027 14.1 0.9 0.068 12.8 0.1 2.0 2 0 0 2 2 2 0 Cytokine-like protein 1 PhoH PF02562.11 KFP02435.1 - 0.031 13.5 0.0 0.12 11.5 0.0 2.1 1 1 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 KFP02435.1 - 0.11 12.3 0.3 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain UvrD-helicase PF00580.16 KFP02435.1 - 0.12 11.5 3.9 1.8 7.8 0.0 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain PNP_UDP_1 PF01048.15 KFP02436.1 - 2e-49 167.6 0.0 2.3e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NLPC_P60 PF00877.14 KFP02436.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 NlpC/P60 family Carboxyl_trans PF01039.17 KFP02437.1 - 3.2e-149 497.4 0.0 1.2e-73 248.1 0.0 2.0 2 0 0 2 2 2 2 Carboxyl transferase domain MdcE PF06833.6 KFP02437.1 - 3.1e-05 23.2 0.2 0.17 11.0 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Myb_DNA-binding PF00249.26 KFP02438.1 - 0.00075 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNA_pol_3_Rpc31 PF11705.3 KFP02438.1 - 6.5 6.6 29.5 8.3 6.2 10.1 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 4F5 PF04419.9 KFP02439.1 - 1.4e-07 32.1 10.1 1.4e-07 32.1 7.0 2.1 2 0 0 2 2 2 1 4F5 protein family Toxin_39 PF15500.1 KFP02439.1 - 3.2 7.9 5.5 5.4 7.2 3.8 1.4 1 1 0 1 1 1 0 Putative RNase-like toxin Ssl1 PF04056.9 KFP02440.1 - 8.6e-93 309.2 0.1 1.1e-92 308.8 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 KFP02440.1 - 4.6e-15 56.1 0.0 6.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.7 KFP02440.1 - 3.6e-13 49.3 30.3 4.7e-13 48.9 15.6 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA PF00092.23 KFP02440.1 - 0.00039 20.2 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFP02440.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain IBR PF01485.16 KFP02440.1 - 4.9 7.1 19.5 2.4 8.0 8.6 2.7 2 0 0 2 2 2 0 IBR domain Occludin_ELL PF07303.8 KFP02441.1 - 1.1e-29 103.1 11.3 1.1e-29 103.1 7.8 1.4 2 0 0 2 2 2 1 Occludin homology domain MARVEL PF01284.18 KFP02441.1 - 1.9e-14 53.7 7.3 2.5e-14 53.3 5.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Shisa PF13908.1 KFP02441.1 - 0.013 15.7 0.1 0.069 13.3 0.0 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tex_N PF09371.5 KFP02441.1 - 0.079 12.2 2.6 0.12 11.6 1.8 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain AAA_23 PF13476.1 KFP02441.1 - 0.12 12.6 1.7 0.15 12.3 1.2 1.2 1 0 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 KFP02442.1 - 5.7e-33 114.1 0.0 6.3e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CDO_I PF05995.7 KFP02443.1 - 3.8e-47 159.6 0.1 4.4e-47 159.5 0.1 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KFP02443.1 - 4.5e-05 22.8 0.3 8.8e-05 21.9 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) 2OG-FeII_Oxy_4 PF13661.1 KFP02443.1 - 0.039 13.5 0.2 0.086 12.4 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Clat_adaptor_s PF01217.15 KFP02444.1 - 1.2e-41 141.7 2.9 1.4e-41 141.5 2.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ARF7EP_C PF14949.1 KFP02445.1 - 2.5e-35 121.0 14.0 2.8e-35 120.8 9.7 1.0 1 0 0 1 1 1 1 ARF7 effector protein C-terminus Herpes_U5 PF05999.6 KFP02445.1 - 1.6 7.2 5.1 1.6 7.2 3.6 1.0 1 0 0 1 1 1 0 Herpesvirus U5-like family HCaRG PF07258.9 KFP02446.1 - 5e-26 91.3 5.8 5.7e-26 91.1 4.0 1.0 1 0 0 1 1 1 1 HCaRG protein Sema PF01403.14 KFP02447.1 - 9.3e-143 475.8 0.2 1.4e-142 475.2 0.1 1.2 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFP02447.1 - 4.1e-08 33.2 2.3 9.2e-08 32.1 1.6 1.6 1 0 0 1 1 1 1 Plexin repeat DTW PF03942.10 KFP02449.1 - 1.6e-45 154.8 0.5 2e-45 154.5 0.3 1.1 1 0 0 1 1 1 1 DTW domain Rav1p_C PF12234.3 KFP02450.1 - 1.8e-78 264.3 0.3 5.6e-76 256.0 0.2 3.1 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KFP02450.1 - 1.8e-26 90.9 29.2 4.4e-06 26.3 0.0 11.9 12 0 0 12 12 12 8 WD domain, G-beta repeat DUF758 PF05527.6 KFP02451.1 - 1.8e-92 308.0 8.6 2e-92 307.9 6.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) RAG1 PF12940.2 KFP02451.1 - 0.00051 18.5 0.8 0.00063 18.2 0.5 1.1 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) Pico_P2B PF01552.12 KFP02451.1 - 0.0043 17.1 1.0 0.013 15.6 0.3 2.1 1 1 0 1 1 1 1 Picornavirus 2B protein CH PF00307.26 KFP02451.1 - 0.013 15.5 0.1 0.042 13.8 0.0 2.0 1 1 1 2 2 2 0 Calponin homology (CH) domain Nup54 PF13874.1 KFP02451.1 - 0.017 14.8 2.1 0.019 14.6 0.9 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FadR_C PF07840.7 KFP02451.1 - 0.02 14.5 0.8 0.03 13.9 0.5 1.3 1 0 0 1 1 1 0 FadR C-terminal domain UCH PF00443.24 KFP02451.1 - 0.035 13.2 1.4 0.043 12.9 1.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF2408 PF10303.4 KFP02451.1 - 0.05 13.7 4.4 0.1 12.6 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HD_3 PF13023.1 KFP02451.1 - 0.064 12.9 0.6 0.11 12.2 0.4 1.5 2 0 0 2 2 2 0 HD domain MaoC_dehydratas PF01575.14 KFP02452.1 - 6.9e-36 122.3 0.0 1.2e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain SCP2 PF02036.12 KFP02452.1 - 1.7e-25 89.2 0.3 3.9e-25 88.0 0.2 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family adh_short PF00106.20 KFP02452.1 - 2.4e-25 89.3 0.1 4.9e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP02452.1 - 7.3e-12 45.3 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 KR domain MaoC_dehydrat_N PF13452.1 KFP02452.1 - 1.2e-10 41.2 0.0 5.4e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Alkyl_sulf_C PF14864.1 KFP02452.1 - 4.9e-08 32.9 0.1 1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF2808 PF10989.3 KFP02452.1 - 0.11 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Collagen PF01391.13 KFP02455.1 - 2.5e-32 110.2 118.7 8.5e-11 41.2 14.5 4.1 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) C4 PF01413.14 KFP02456.1 - 4.1e-91 300.5 2.3 8.1e-47 157.8 0.2 2.0 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen COMP PF11598.3 KFP02456.1 - 0.42 10.7 2.2 1.3 9.1 0.2 2.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Ras PF00071.17 KFP02457.1 - 4.6e-32 110.6 0.0 1.3e-31 109.1 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFP02457.1 - 1.1e-14 54.9 0.0 2.1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP02457.1 - 5.9e-14 51.6 0.0 7.3e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP02457.1 - 0.00013 21.4 0.0 0.002 17.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP02457.1 - 0.00061 19.7 0.0 0.001 19.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFP02457.1 - 0.047 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KFP02457.1 - 0.06 13.0 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Gtr1_RagA PF04670.7 KFP02457.1 - 0.07 12.2 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Carb_kinase PF01256.12 KFP02458.1 - 4.4e-55 186.6 0.0 5.1e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 KFP02458.1 - 0.027 13.6 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Suc_Fer-like PF06999.7 KFP02458.1 - 0.065 13.2 0.1 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like tRNA-synt_1e PF01406.14 KFP02459.1 - 2.1e-98 329.2 0.4 2.6e-98 328.8 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KFP02459.1 - 2.9e-10 39.3 0.5 6.1e-05 21.8 0.2 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFP02459.1 - 0.00042 18.4 0.0 0.00056 18.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 KFP02459.1 - 0.00069 19.8 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.13 KFP02459.1 - 0.027 13.1 0.5 0.066 11.8 0.1 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (K) ING PF12998.2 KFP02460.1 - 2.1e-33 114.7 5.8 2.1e-33 114.7 4.0 2.3 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFP02460.1 - 1.6e-10 40.4 8.7 3.8e-10 39.2 6.1 1.7 1 0 0 1 1 1 1 PHD-finger SRP-alpha_N PF04086.8 KFP02460.1 - 0.018 14.4 15.7 0.031 13.6 10.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PHD_2 PF13831.1 KFP02460.1 - 0.028 13.7 3.8 0.052 12.8 2.6 1.4 1 0 0 1 1 1 0 PHD-finger DUF4661 PF15576.1 KFP02460.1 - 0.051 13.2 4.0 0.075 12.6 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) FadA PF09403.5 KFP02460.1 - 0.054 13.5 0.7 0.054 13.5 0.5 2.9 1 1 0 2 2 1 0 Adhesion protein FadA ApoB100_C PF12491.3 KFP02460.1 - 0.069 12.8 0.6 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal zf-HC5HC2H PF13771.1 KFP02460.1 - 0.1 12.7 2.6 0.43 10.7 1.8 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain Hid1 PF12722.2 KFP02460.1 - 0.37 8.4 11.0 0.46 8.1 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING-like PF08746.6 KFP02460.1 - 0.92 9.5 6.7 2.1 8.4 4.6 1.7 1 0 0 1 1 1 0 RING-like domain DDHD PF02862.12 KFP02460.1 - 1.7 8.4 7.6 2.7 7.7 5.3 1.5 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KFP02460.1 - 4.5 7.0 12.4 6.9 6.4 8.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ank_2 PF12796.2 KFP02461.1 - 1.1e-26 92.9 0.4 2.9e-17 62.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP02461.1 - 4.4e-19 67.2 2.3 1.3e-06 27.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFP02461.1 - 7.9e-17 60.9 1.1 1.4e-08 34.7 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP02461.1 - 2.5e-16 59.6 0.7 8.4e-08 32.5 0.0 3.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02461.1 - 3.4e-11 42.2 0.1 6.4e-05 22.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat RhoGEF PF00621.15 KFP02462.1 - 6.9e-32 110.7 0.7 6.9e-32 110.7 0.5 2.8 3 0 0 3 3 3 1 RhoGEF domain SH3_9 PF14604.1 KFP02462.1 - 7.9e-18 63.7 0.1 1.6e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP02462.1 - 1.2e-17 63.0 0.2 2.2e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP02462.1 - 5.3e-17 61.0 0.3 1.3e-16 59.8 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFP02462.1 - 3.4e-09 36.8 0.7 7.2e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 PH domain GlutR_dimer PF00745.15 KFP02462.1 - 0.11 12.4 4.1 0.32 10.9 2.8 1.7 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Cep57_MT_bd PF06657.8 KFP02462.1 - 0.41 10.6 7.6 0.4 10.6 2.3 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HLH PF00010.21 KFP02463.1 - 1.6e-05 24.4 0.6 2.1e-05 24.1 0.4 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RhoGAP PF00620.22 KFP02464.1 - 7.6e-48 161.9 0.5 1.6e-47 160.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FF PF01846.14 KFP02464.1 - 1.1e-14 54.1 17.0 1.4e-09 37.7 0.8 4.9 5 0 0 5 5 5 3 FF domain Ras PF00071.17 KFP02464.1 - 1e-13 51.0 4.0 3.7e-05 23.1 0.2 4.5 4 0 0 4 4 4 4 Ras family GTP_EFTU PF00009.22 KFP02464.1 - 0.0018 17.7 0.2 0.0054 16.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFP02464.1 - 0.0021 18.1 0.2 3.3 7.8 0.1 3.1 2 1 0 2 2 2 2 AAA domain ParA PF10609.4 KFP02465.1 - 7.1e-37 125.1 0.2 2.3e-36 123.5 0.1 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KFP02465.1 - 1.4e-13 50.7 0.0 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFP02465.1 - 3.5e-09 36.7 0.0 2.5e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KFP02465.1 - 1.1e-07 31.2 0.0 1.9e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KFP02465.1 - 6.6e-05 22.1 0.6 0.00089 18.3 0.2 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 KFP02465.1 - 0.00039 19.7 0.1 0.0026 16.9 0.0 2.1 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 KFP02465.1 - 0.0028 17.0 0.2 0.0067 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFP02465.1 - 0.0063 16.2 0.7 0.2 11.3 0.5 2.3 2 0 0 2 2 2 1 Part of AAA domain VirC1 PF07015.6 KFP02465.1 - 0.011 14.7 0.1 0.027 13.5 0.0 1.5 2 0 0 2 2 2 0 VirC1 protein Tyr_Deacylase PF02580.11 KFP02466.1 - 2e-37 128.3 0.0 2.3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HEAT_2 PF13646.1 KFP02467.1 - 6.2e-13 48.8 16.9 0.23 11.7 0.1 9.7 8 2 1 10 10 10 5 HEAT repeats HEAT PF02985.17 KFP02467.1 - 7.8e-11 41.1 34.0 0.021 14.8 0.3 11.8 12 0 0 12 12 12 4 HEAT repeat Vac14_Fab1_bd PF12755.2 KFP02467.1 - 7.8e-05 22.9 0.1 0.0016 18.7 0.0 3.3 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFP02467.1 - 0.0049 17.3 33.4 1.8 9.1 0.1 10.5 10 1 1 11 11 11 4 HEAT-like repeat HECT PF00632.20 KFP02468.1 - 1.3e-84 284.0 0.0 2.5e-84 283.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.8 KFP02468.1 - 3.1e-24 84.7 3.9 7.9e-24 83.4 2.7 1.8 1 0 0 1 1 1 1 Mib_herc2 Sad1_UNC PF07738.8 KFP02468.1 - 2.8e-23 82.1 0.0 5.8e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ank_2 PF12796.2 KFP02468.1 - 4.8e-17 62.0 0.0 2.1e-16 60.0 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP02468.1 - 4.5e-16 57.7 0.0 9.8e-06 25.1 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFP02468.1 - 1.7e-12 47.1 0.1 5.3e-09 36.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP02468.1 - 1.3e-10 41.4 0.0 3.4e-07 30.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02468.1 - 3.9e-09 35.8 0.0 0.0081 16.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat F5_F8_type_C PF00754.20 KFP02468.1 - 2e-05 24.4 0.1 5.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Lipase_chap PF03280.9 KFP02468.1 - 0.22 11.0 0.2 0.45 10.0 0.1 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Clat_adaptor_s PF01217.15 KFP02469.1 - 4.2e-38 130.2 7.6 4.8e-38 130.0 5.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain WD40 PF00400.27 KFP02470.1 - 4.1e-46 153.2 8.9 4.5e-10 39.0 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.7 KFP02470.1 - 1.4e-25 90.1 1.2 1.4e-25 90.1 0.8 2.5 3 0 0 3 3 3 1 Striatin family Nup160 PF11715.3 KFP02470.1 - 4e-05 21.9 0.3 0.5 8.4 0.1 3.1 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFP02470.1 - 0.00032 19.5 0.1 0.062 12.0 0.1 2.9 2 1 0 3 3 3 1 Nup133 N terminal like VWA PF00092.23 KFP02471.1 - 3.6e-80 267.8 0.5 3.4e-41 140.9 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain LCCL PF03815.14 KFP02471.1 - 1.2e-22 79.6 0.0 2.7e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 LCCL domain VWA_2 PF13519.1 KFP02471.1 - 8.6e-17 61.7 0.0 2.5e-10 40.7 0.0 2.3 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 KFP02471.1 - 3.8e-05 23.4 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF3606 PF12244.3 KFP02471.1 - 0.13 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Sec1 PF00995.18 KFP02472.1 - 1.1e-141 473.3 1.0 2.1e-141 472.3 0.7 1.4 1 1 0 1 1 1 1 Sec1 family cwf21 PF08312.7 KFP02472.1 - 0.016 15.0 0.2 0.29 11.0 0.0 2.8 3 0 0 3 3 3 0 cwf21 domain zf-HC5HC2H PF13771.1 KFP02473.1 - 7.1e-20 70.9 4.1 7.1e-20 70.9 2.8 3.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain HECT PF00632.20 KFP02473.1 - 7.3e-13 48.3 0.8 1.2e-12 47.6 0.6 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Nbl1_Borealin_N PF10444.4 KFP02473.1 - 3.7 6.9 6.2 11 5.4 0.1 3.6 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal Pkinase PF00069.20 KFP02474.1 - 2.3e-64 217.0 0.0 3.8e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02474.1 - 9.4e-33 113.3 0.0 1.5e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFP02474.1 - 2.7e-27 94.2 19.8 9.2e-14 50.9 5.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFP02474.1 - 1.5e-09 38.0 0.0 8.8e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 KFP02474.1 - 0.00011 21.3 0.0 0.00077 18.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KFP02474.1 - 0.00038 19.5 0.0 0.00078 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFP02474.1 - 0.049 12.4 0.1 0.077 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KFP02474.1 - 0.12 12.1 0.3 2.1 7.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family C1_3 PF07649.7 KFP02474.1 - 0.12 12.4 13.4 1.5 8.8 1.0 2.6 2 0 0 2 2 2 0 C1-like domain zf-RING-like PF08746.6 KFP02474.1 - 0.14 12.2 17.5 0.74 9.8 3.3 2.8 2 0 0 2 2 2 0 RING-like domain PHD PF00628.24 KFP02474.1 - 0.31 10.7 17.7 0.85 9.3 3.5 2.5 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 KFP02474.1 - 0.51 10.1 16.1 0.37 10.5 1.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.11 KFP02474.1 - 0.55 10.1 10.7 2.6 7.9 3.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.1 KFP02474.1 - 0.61 9.4 10.0 1 8.6 0.4 2.9 2 0 0 2 2 2 0 PHD-finger DZR PF12773.2 KFP02474.1 - 2.7 7.9 12.9 0.11 12.3 0.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.20 KFP02476.1 - 7e-49 166.3 0.0 9.4e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02476.1 - 1e-32 113.2 0.0 1.4e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFP02476.1 - 2.2e-15 55.6 0.5 4.4e-15 54.6 0.3 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFP02476.1 - 2.7e-13 50.3 10.8 2.7e-13 50.3 7.5 2.3 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 KFP02476.1 - 0.18 11.4 0.0 0.52 9.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family LIM PF00412.17 KFP02477.1 - 1.9e-37 127.1 31.6 2.1e-13 50.0 2.9 3.2 3 0 0 3 3 3 3 LIM domain PDZ PF00595.19 KFP02477.1 - 2.7e-08 33.8 0.3 5.8e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP02477.1 - 0.00044 20.0 0.2 0.00094 19.0 0.0 1.7 2 0 0 2 2 2 1 PDZ domain 7tm_1 PF00001.16 KFP02478.1 - 4.8e-59 199.5 17.3 5.8e-59 199.3 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02478.1 - 4.5e-14 52.2 15.8 6.3e-14 51.7 11.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP02478.1 - 1.8e-08 33.8 16.9 3e-08 33.1 11.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 KFP02478.1 - 6.8e-06 25.4 8.7 9.5e-06 24.9 6.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.1 KFP02478.1 - 0.003 17.3 1.9 0.003 17.3 1.3 2.7 3 0 0 3 3 3 1 Olfactory receptor TerC PF03741.11 KFP02478.1 - 0.52 9.7 11.6 0.032 13.6 2.9 2.4 1 1 1 2 2 2 0 Integral membrane protein TerC family DUF2852 PF11014.3 KFP02478.1 - 0.99 9.3 5.2 6 6.8 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Git3 PF11710.3 KFP02478.1 - 1.6 8.2 18.3 0.065 12.7 8.7 1.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 WAPL PF07814.8 KFP02479.1 - 3.7e-147 489.7 7.6 6.6e-147 488.9 5.3 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPF0560 PF10577.4 KFP02481.1 - 4.6e-211 703.2 19.9 1.4e-116 390.7 2.7 2.8 1 1 1 2 2 2 2 Uncharacterised protein family UPF0560 Prominin PF05478.6 KFP02481.1 - 0.0042 14.7 0.1 0.0063 14.1 0.1 1.1 1 0 0 1 1 1 1 Prominin FAM163 PF15069.1 KFP02481.1 - 0.048 14.2 0.6 0.14 12.7 0.0 2.2 3 0 0 3 3 3 0 FAM163 family RCC1_2 PF13540.1 KFP02481.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Orthoreo_P10 PF07204.6 KFP02481.1 - 0.25 11.1 1.3 0.35 10.6 0.2 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Shisa PF13908.1 KFP02481.1 - 2.3 8.3 6.0 0.51 10.4 0.9 2.4 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Integrin_alpha2 PF08441.7 KFP02482.1 - 2.7e-114 382.5 0.0 3.3e-114 382.2 0.0 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 KFP02482.1 - 6e-24 83.0 22.6 1.6e-07 30.7 0.5 4.5 4 0 0 4 4 4 4 FG-GAP repeat VCBS PF13517.1 KFP02482.1 - 5.6e-15 55.4 8.8 5.9e-06 26.5 0.9 4.6 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 KFP02482.1 - 4.3e-05 22.9 0.9 9.2e-05 21.9 0.6 1.6 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region TcdB_toxin_midN PF12256.3 KFP02482.1 - 0.021 14.2 0.9 1.4 8.2 0.0 2.9 2 1 1 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region DUF1049 PF06305.6 KFP02482.1 - 0.022 14.2 0.2 0.044 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CD34_antigen PF06365.7 KFP02482.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF1191 PF06697.7 KFP02482.1 - 0.19 10.5 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) zf-CCCH PF00642.19 KFP02483.1 - 7.7e-06 25.4 0.8 7.7e-06 25.4 0.6 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFP02483.1 - 0.0053 16.7 10.9 0.11 12.5 3.3 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type Phe_tRNA-synt_N PF02912.13 KFP02484.1 - 0.054 13.2 0.3 4.8 6.9 0.0 3.0 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain zf-C2H2_jaz PF12171.3 KFP02485.1 - 1.5e-05 24.9 8.8 1.5e-05 24.9 6.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP02485.1 - 0.00076 19.5 1.9 0.0049 17.0 1.3 2.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Phe_tRNA-synt_N PF02912.13 KFP02487.1 - 0.1 12.3 0.1 4.6 7.0 0.0 2.9 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Frizzled PF01534.12 KFP02489.1 - 6.1e-147 488.6 19.6 7e-147 488.4 13.6 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Ndc1_Nup PF09531.5 KFP02489.1 - 0.071 11.5 1.9 0.17 10.2 1.3 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-DHHC PF01529.15 KFP02489.1 - 1.1 8.6 10.4 0.21 10.9 0.1 3.0 2 1 1 3 3 3 0 DHHC palmitoyltransferase Rad60-SLD PF11976.3 KFP02490.1 - 4.5e-23 80.7 0.2 5.4e-23 80.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFP02490.1 - 1.9e-17 62.3 0.6 2.3e-17 62.1 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Nop PF01798.13 KFP02491.1 - 9e-60 200.3 0.6 2.1e-59 199.1 0.4 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KFP02491.1 - 1.3e-28 98.5 0.0 2.9e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KFP02491.1 - 2.3e-13 50.0 1.7 6.7e-13 48.6 1.2 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Pkinase PF00069.20 KFP02492.1 - 2.3e-47 161.3 0.0 3.8e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02492.1 - 4.9e-30 104.4 0.0 1.1e-29 103.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 KFP02492.1 - 2.9e-12 47.0 8.6 2.9e-12 47.0 6.0 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 KFP02492.1 - 0.0004 20.1 0.0 0.0013 18.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family FAM117 PF15388.1 KFP02493.1 - 5e-121 403.8 14.2 6.3e-121 403.4 9.8 1.1 1 0 0 1 1 1 1 Protein Family FAM117 WD40 PF00400.27 KFP02494.1 - 5.8e-53 174.9 30.8 2.1e-10 40.0 0.6 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat NLE PF08154.7 KFP02494.1 - 3.6e-14 52.5 0.0 6.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ALS2CR8 PF15299.1 KFP02495.1 - 2.3e-58 197.4 0.1 3e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF4206 PF13901.1 KFP02496.1 - 1.4e-74 250.0 9.2 2.9e-74 249.0 6.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) PH PF00169.24 KFP02496.1 - 3.5e-14 52.8 0.1 3e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 PH domain MAAL_N PF05034.8 KFP02496.1 - 0.074 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus Frizzled PF01534.12 KFP02497.1 - 2.4e-147 489.9 12.3 3e-147 489.6 8.5 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFP02497.1 - 3e-06 27.5 0.2 7.4e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Fz domain 7tm_1 PF00001.16 KFP02497.1 - 0.063 12.4 9.3 0.024 13.8 4.1 2.0 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1230 PF06799.6 KFP02497.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1230) Cyclin_N PF00134.18 KFP02498.1 - 1.9e-15 56.5 0.3 3.3e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFP02498.1 - 4.6e-12 46.5 0.5 6.6e-12 46.0 0.1 1.5 2 0 0 2 2 2 1 Cyclin Methyltransf_16 PF10294.4 KFP02499.1 - 4e-43 146.8 0.0 5e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KFP02499.1 - 2.1e-05 23.8 0.0 2.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 KFP02499.1 - 6.8e-05 22.6 0.0 8.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP02499.1 - 0.0001 22.8 0.0 0.00016 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP02499.1 - 0.00018 20.9 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFP02499.1 - 0.0074 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain zf-H2C2_2 PF13465.1 KFP02500.1 - 1.7e-10 40.6 21.1 9.8e-06 25.6 0.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP02500.1 - 4.7e-06 26.6 12.6 0.00041 20.5 0.4 3.9 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP02500.1 - 3.4e-05 23.8 19.4 0.0037 17.5 0.9 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP02500.1 - 0.24 11.6 0.1 0.24 11.6 0.0 3.9 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Peptidase_M14 PF00246.19 KFP02501.1 - 8.8e-83 278.1 0.0 1.1e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFP02501.1 - 8e-14 51.0 0.1 8e-14 51.0 0.1 1.7 2 0 0 2 2 2 1 Carboxypeptidase activation peptide FAST_1 PF06743.10 KFP02502.1 - 6.2e-15 54.6 0.3 6.2e-15 54.6 0.2 4.4 4 2 1 5 5 5 1 FAST kinase-like protein, subdomain 1 FAST_2 PF08368.7 KFP02502.1 - 1.4e-13 50.9 0.2 8.6e-13 48.4 0.0 2.5 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 2 RAP PF08373.5 KFP02502.1 - 9.2e-09 34.9 0.0 1.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RAP domain Ldh_1_C PF02866.13 KFP02503.1 - 1.2e-13 51.1 0.0 1.2e-09 38.1 0.0 2.4 2 0 0 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain EF-hand_3 PF09069.6 KFP02504.1 - 8.8e-18 64.1 0.0 1.2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 EF-hand EF-hand_2 PF09068.6 KFP02504.1 - 0.002 18.2 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 EF hand DED PF01335.16 KFP02507.1 - 1.8e-36 124.1 14.8 2.8e-18 65.7 0.8 3.2 3 0 0 3 3 3 2 Death effector domain Peptidase_C14 PF00656.17 KFP02507.1 - 1.2e-32 113.5 0.0 1.9e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 KFP02508.1 - 5.3e-39 134.3 0.0 8.2e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain DED PF01335.16 KFP02508.1 - 1e-29 102.4 22.3 1.8e-16 60.0 3.0 3.2 3 0 0 3 3 3 2 Death effector domain Pro_isomerase PF00160.16 KFP02509.1 - 1.6e-51 174.5 0.1 1.8e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NIF3 PF01784.13 KFP02510.1 - 2.9e-76 256.2 0.0 3.9e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ORC2 PF04084.9 KFP02511.1 - 1.2e-107 359.5 0.4 1.8e-107 358.9 0.3 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 SDA1 PF05285.7 KFP02511.1 - 0.27 10.4 8.5 0.44 9.7 5.9 1.2 1 0 0 1 1 1 0 SDA1 Hyccin PF09790.4 KFP02512.1 - 5.1e-132 439.4 0.1 6.3e-132 439.1 0.0 1.1 1 0 0 1 1 1 1 Hyccin NDUF_B12 PF08122.7 KFP02513.1 - 4e-23 80.9 0.6 5.1e-23 80.5 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Pkinase PF00069.20 KFP02514.1 - 3.9e-70 235.9 0.1 5.7e-70 235.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02514.1 - 2.7e-26 92.1 0.1 1.6e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Shugoshin_C PF07557.6 KFP02515.1 - 9.9e-08 31.3 2.8 9.9e-08 31.3 2.0 1.7 2 0 0 2 2 2 1 Shugoshin C terminus BTB_2 PF02214.17 KFP02516.1 - 6.9e-14 51.8 0.0 3.2e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF1387 PF07139.6 KFP02517.1 - 1.1e-105 353.6 19.5 1.1e-105 353.6 13.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1387) Tim44 PF04280.10 KFP02518.1 - 1.5e-05 25.0 0.3 4.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Tim44-like domain MBA1 PF07961.6 KFP02518.1 - 0.0023 16.8 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Cupin_8 PF13621.1 KFP02519.1 - 8.9e-43 146.5 0.0 1.1e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFP02519.1 - 1.2e-10 41.2 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KFP02519.1 - 0.0076 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF1493 PF07377.7 KFP02519.1 - 0.037 14.1 0.6 0.095 12.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) UPF0565 PF10561.4 KFP02520.1 - 4.5e-82 275.3 0.1 5.1e-82 275.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 CUT PF02376.10 KFP02521.1 - 2e-52 174.9 8.2 4.1e-27 93.8 0.1 3.8 4 0 0 4 4 4 2 CUT domain Homeobox PF00046.24 KFP02521.1 - 3.3e-07 29.8 0.0 1.1e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Homeobox domain PI-PLC-X PF00388.14 KFP02522.1 - 5.5e-49 165.3 0.0 1.3e-48 164.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFP02522.1 - 2.4e-44 150.0 0.3 5.6e-44 148.9 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFP02522.1 - 3.2e-24 84.7 0.1 9.2e-24 83.2 0.1 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFP02522.1 - 5.5e-18 64.5 0.0 1.4e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KFP02522.1 - 0.0011 19.0 0.3 0.088 12.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair Mcp5_PH PF12814.2 KFP02522.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 KFP02522.1 - 0.05 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 PH domain Raftlin PF15250.1 KFP02523.1 - 7.3e-198 657.7 0.0 8.5e-198 657.4 0.0 1.0 1 0 0 1 1 1 1 Raftlin Mob1_phocein PF03637.12 KFP02524.1 - 1.4e-60 203.9 1.4 1.7e-60 203.6 1.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Cpn10 PF00166.16 KFP02525.1 - 1.3e-29 101.9 0.4 1.5e-29 101.7 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.19 KFP02526.1 - 3.5e-119 398.6 13.0 3.9e-119 398.4 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 KFP02526.1 - 0.066 12.8 2.6 0.68 9.6 0.2 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1547) Polyketide_cyc PF03364.15 KFP02527.1 - 3e-24 85.4 0.0 3.8e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ank PF00023.25 KFP02528.1 - 2.7e-194 620.2 75.2 5.5e-10 38.5 0.5 27.2 27 0 0 27 27 27 26 Ankyrin repeat Ank_2 PF12796.2 KFP02528.1 - 1.9e-193 627.4 60.6 1.3e-23 83.1 0.2 13.7 2 2 10 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP02528.1 - 1.5e-159 515.8 55.9 4e-15 55.8 0.2 21.1 6 5 17 23 23 23 23 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP02528.1 - 8.1e-139 448.5 69.6 1.9e-10 40.6 0.1 23.1 5 4 19 24 24 24 24 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02528.1 - 7.1e-124 391.1 62.8 3.5e-08 32.9 0.1 27.0 27 0 0 27 27 27 24 Ankyrin repeat Ribosomal_S6 PF01250.12 KFP02528.1 - 0.073 12.9 0.0 6.2 6.7 0.0 3.7 4 1 1 5 5 5 0 Ribosomal protein S6 HECT PF00632.20 KFP02530.1 - 3.6e-93 312.1 0.0 5.8e-93 311.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFP02530.1 - 3e-17 62.1 0.3 3.5e-09 36.3 0.2 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.25 KFP02530.1 - 1.8e-10 40.5 0.0 3.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain RFXA_RFXANK_bdg PF15289.1 KFP02530.1 - 0.97 9.6 3.8 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Pkinase PF00069.20 KFP02531.1 - 3.2e-65 219.8 0.0 3.8e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02531.1 - 6.9e-37 126.9 0.0 8.4e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP02531.1 - 0.0014 17.6 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP02531.1 - 0.0099 15.6 0.2 0.024 14.3 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFP02531.1 - 0.026 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KFP02531.1 - 0.038 13.0 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BIR PF00653.16 KFP02532.1 - 1.1e-19 70.6 4.5 1.1e-19 70.6 3.2 1.9 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 KFP02532.1 - 0.0016 18.2 3.1 0.0019 17.9 2.2 1.5 1 1 0 1 1 1 1 C3HC zinc finger-like Zip PF02535.17 KFP02533.1 - 2.2e-104 348.8 11.3 2.2e-104 348.8 7.8 4.3 2 1 1 3 3 3 1 ZIP Zinc transporter Feld-I_B PF09252.5 KFP02533.1 - 0.0093 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Allergen Fel d I-B chain DUF443 PF04276.7 KFP02533.1 - 2.3 7.5 6.2 0.13 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Dicty_REP PF05086.7 KFP02533.1 - 4.9 4.7 6.4 8.9 3.9 4.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleo_P87 PF07267.6 KFP02533.1 - 8.6 4.9 10.8 14 4.2 7.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Yae1_N PF09811.4 KFP02534.1 - 0.048 13.1 9.3 0.62 9.6 1.4 2.2 1 1 1 2 2 2 0 Essential protein Yae1, N terminal PT PF04886.7 KFP02535.1 - 0.019 14.2 0.0 3.9 6.8 0.0 3.2 2 1 0 2 2 2 0 PT repeat RVT_1 PF00078.22 KFP02536.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MIF4G PF02854.14 KFP02537.1 - 1.7e-26 92.9 5.5 2.5e-26 92.4 3.8 1.2 1 0 0 1 1 1 1 MIF4G domain Cauli_AT PF03233.8 KFP02537.1 - 0.085 12.5 2.8 0.19 11.4 1.9 1.5 1 0 0 1 1 1 0 Aphid transmission protein Zip PF02535.17 KFP02537.1 - 9.3 5.1 7.1 2.8 6.8 1.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter MH2 PF03166.9 KFP02538.1 - 2e-62 210.2 0.1 2.3e-62 210.0 0.1 1.0 1 0 0 1 1 1 1 MH2 domain SH3BP5 PF05276.9 KFP02539.1 - 4.3e-92 307.7 16.8 4.3e-92 307.7 11.7 1.7 2 0 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) DUF2884 PF11101.3 KFP02539.1 - 0.034 13.5 7.5 0.056 12.8 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Med28 PF11594.3 KFP02539.1 - 0.17 12.1 9.2 0.85 9.8 1.1 2.8 1 1 1 2 2 2 0 Mediator complex subunit 28 Exonuc_VII_L PF02601.10 KFP02539.1 - 0.45 9.6 11.0 0.87 8.7 7.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rootletin PF15035.1 KFP02539.1 - 2.2 8.2 18.8 2.2 8.2 7.4 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion H-kinase_dim PF02895.9 KFP02539.1 - 6.6 7.1 7.0 1e+02 3.3 4.8 3.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Calpain_III PF01067.17 KFP02540.1 - 1.9e-24 86.0 0.2 9.6e-17 60.9 0.0 2.5 2 1 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KFP02541.1 - 2.8e-24 85.6 0.1 2.6e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease MIT PF04212.13 KFP02541.1 - 1.5e-16 60.0 5.7 6.6e-14 51.5 2.2 2.3 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 KFP02541.1 - 0.022 14.4 0.7 0.022 14.4 0.5 2.0 2 0 0 2 2 2 0 TPR repeat YfdX PF10938.3 KFP02541.1 - 0.03 13.9 0.7 0.03 13.9 0.5 2.1 2 0 0 2 2 2 0 YfdX protein TPR_2 PF07719.12 KFP02541.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP02541.1 - 0.44 10.4 2.1 0.94 9.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PRCC PF10253.4 KFP02541.1 - 2.7 8.6 9.1 1.7 9.3 4.6 1.7 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting ISG65-75 PF11727.3 KFP02541.1 - 5.5 5.9 9.5 0.66 8.9 1.2 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein Pkinase PF00069.20 KFP02542.1 - 3.7e-23 82.0 0.2 1.3e-22 80.1 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain WD40 PF00400.27 KFP02542.1 - 1.1e-18 66.3 11.8 7.7e-08 31.9 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.17 KFP02542.1 - 1.1e-10 40.7 1.9 0.043 13.9 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.12 KFP02542.1 - 3.1e-07 29.7 0.0 1.6e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Nucleoporin_N PF08801.6 KFP02542.1 - 0.00024 19.9 0.2 1.1 7.9 0.0 3.7 2 1 1 4 4 4 2 Nup133 N terminal like HEAT_2 PF13646.1 KFP02542.1 - 0.00047 20.3 0.6 0.31 11.3 0.1 3.8 2 1 1 3 3 3 1 HEAT repeats XPG_I_2 PF12813.2 KFP02543.1 - 9e-16 58.1 0.0 1.2e-14 54.3 0.0 2.3 1 1 0 1 1 1 1 XPG domain containing Protoglobin PF11563.3 KFP02543.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Protoglobin Pkinase PF00069.20 KFP02544.1 - 1.7e-65 220.7 0.3 4.1e-65 219.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02544.1 - 6.8e-46 156.4 0.0 1.9e-45 154.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase ASF1_hist_chap PF04729.8 KFP02544.1 - 0.023 14.3 0.0 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 ASF1 like histone chaperone APH PF01636.18 KFP02544.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L3 PF00297.17 KFP02545.1 - 4.9e-42 144.1 2.6 2.1e-39 135.5 1.8 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Copine PF07002.11 KFP02546.1 - 1.7e-64 215.9 0.1 3.5e-64 214.9 0.0 1.6 1 0 0 1 1 1 1 Copine C2 PF00168.25 KFP02546.1 - 4.1e-25 87.4 0.2 5.1e-13 48.6 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFP02546.1 - 6.9e-09 35.8 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 KFP02546.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain His_Phos_2 PF00328.17 KFP02547.1 - 1.2e-58 199.1 0.5 1.6e-58 198.6 0.4 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KFP02547.1 - 0.0079 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rax2 PF12768.2 KFP02547.1 - 0.08 12.1 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DnaJ PF00226.26 KFP02548.1 - 6.5e-16 57.8 0.3 6.5e-16 57.8 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain DUF4339 PF14237.1 KFP02548.1 - 6.3e-13 48.0 0.9 2e-12 46.4 0.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) INTS5_N PF14837.1 KFP02548.1 - 0.032 13.6 1.4 0.068 12.5 0.3 2.1 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus GYF PF02213.11 KFP02548.1 - 0.06 12.9 1.0 0.16 11.5 0.7 1.8 1 0 0 1 1 1 0 GYF domain APH PF01636.18 KFP02549.1 - 9.4e-43 146.6 0.1 1.5e-42 145.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.19 KFP02549.1 - 6.7e-34 117.1 0.7 1.1e-33 116.4 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFP02549.1 - 2.3e-16 59.0 0.1 4.3e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFP02549.1 - 4e-13 49.9 0.2 1.4e-12 48.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFP02549.1 - 1.7e-11 44.4 0.2 4.7e-11 43.0 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain EcKinase PF02958.15 KFP02549.1 - 0.00032 19.9 0.0 0.00062 19.0 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KFP02549.1 - 0.0048 16.2 0.0 0.91 8.8 0.0 3.1 3 0 0 3 3 3 1 RIO1 family Astro_capsid_p PF12226.3 KFP02549.1 - 0.15 11.2 0.0 0.39 9.9 0.0 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HTH_28 PF13518.1 KFP02549.1 - 0.82 9.7 3.2 1.7 8.7 0.1 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain 7tm_1 PF00001.16 KFP02550.1 - 5e-50 170.0 17.3 7e-50 169.5 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02550.1 - 2.2e-06 27.0 14.1 2.8e-06 26.6 9.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF621 PF04789.10 KFP02550.1 - 0.0019 17.2 4.4 0.0037 16.3 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF621) DUF2339 PF10101.4 KFP02550.1 - 0.069 11.4 5.9 0.073 11.3 0.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) DUF202 PF02656.10 KFP02550.1 - 0.084 13.0 0.8 4 7.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF202) SirB PF04247.7 KFP02550.1 - 0.15 11.7 4.5 0.11 12.2 1.3 2.1 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB 7tm_4 PF13853.1 KFP02550.1 - 3.1 7.5 16.9 0.094 12.5 5.2 3.0 2 2 1 3 3 3 0 Olfactory receptor DUF3399 PF11879.3 KFP02551.1 - 0.42 10.8 2.2 0.49 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) Filament PF00038.16 KFP02552.1 - 2.2e-54 185.0 25.3 2.7e-54 184.7 17.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 KFP02552.1 - 0.00013 19.9 24.3 0.00091 17.0 6.4 2.1 2 0 0 2 2 2 2 Myosin tail CCDC155 PF14662.1 KFP02552.1 - 0.0024 17.5 12.2 0.0024 17.5 8.5 2.9 2 1 0 3 3 3 1 Coiled-coil region of CCDC155 Baculo_PEP_C PF04513.7 KFP02552.1 - 0.041 13.7 4.9 0.15 11.8 0.2 2.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dimer_Tnp_Tn5 PF02281.11 KFP02552.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain Lectin_N PF03954.9 KFP02552.1 - 0.3 10.4 5.9 0.21 10.9 0.8 2.5 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF948 PF06103.6 KFP02552.1 - 2 8.3 10.1 8.3 6.3 0.1 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Frigida PF07899.6 KFP02552.1 - 3.6 6.2 11.7 2.1 7.0 2.0 2.3 2 0 0 2 2 2 0 Frigida-like protein FlaC_arch PF05377.6 KFP02552.1 - 6.4 6.7 15.7 1 9.2 0.2 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) CDV3 PF15359.1 KFP02553.1 - 1.7e-56 189.7 8.1 2.3e-56 189.3 5.6 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 TEX19 PF15553.1 KFP02553.1 - 1.2 9.0 4.3 0.36 10.6 1.2 1.5 2 0 0 2 2 2 0 Testis-expressed protein 19 BRCT PF00533.21 KFP02554.1 - 3.6e-42 142.3 0.8 1.3e-16 60.4 0.1 4.2 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFP02554.1 - 2.1e-39 133.1 6.3 7.5e-23 80.1 0.9 3.7 4 0 0 4 4 4 3 twin BRCT domain 7tm_1 PF00001.16 KFP02555.1 - 1.9e-56 191.0 20.3 2.3e-56 190.8 14.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02555.1 - 2.7e-09 36.5 22.6 3.5e-09 36.1 15.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 KFP02556.1 - 2.8e-56 190.5 21.8 3.4e-56 190.2 15.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02556.1 - 5.2e-08 32.3 25.1 6.8e-08 31.9 17.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFP02556.1 - 0.3 10.8 17.0 0.031 14.0 6.1 2.9 1 1 1 2 2 2 0 Olfactory receptor 7tm_1 PF00001.16 KFP02557.1 - 8.3e-57 192.2 22.9 1.1e-56 191.7 15.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02557.1 - 0.00029 20.0 23.9 0.00041 19.6 16.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FYVE PF01363.16 KFP02559.1 - 5.2e-16 58.3 18.7 2.6e-15 56.0 13.0 2.3 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.14 KFP02559.1 - 2.6e-09 36.9 9.7 1.2e-08 34.7 0.0 4.4 3 1 0 3 3 3 1 RUN domain GOLD_2 PF13897.1 KFP02559.1 - 1.5e-05 25.2 0.0 1.5e-05 25.2 0.0 6.6 5 2 2 7 7 7 1 Golgi-dynamics membrane-trafficking Myosin_tail_1 PF01576.14 KFP02559.1 - 2.7e-05 22.1 25.2 2.7e-05 22.1 17.5 6.9 2 1 5 7 7 7 3 Myosin tail Ldl_recept_b PF00058.12 KFP02560.1 - 1.3e-153 499.0 49.3 5.9e-13 48.9 0.0 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFP02560.1 - 1.4e-37 127.4 65.2 1.1e-12 47.7 5.5 5.5 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.13 KFP02560.1 - 6.7e-32 109.1 58.4 9e-13 47.8 7.6 4.4 5 0 0 5 5 5 3 Low-density lipoprotein receptor domain class A SGL PF08450.7 KFP02560.1 - 1.7e-18 66.8 22.4 0.028 13.8 0.5 11.1 8 3 3 12 12 12 7 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KFP02560.1 - 3.6e-09 36.4 0.0 8.9 6.3 0.0 8.2 8 1 1 9 9 9 1 Arylesterase NHL PF01436.16 KFP02560.1 - 0.00019 21.2 0.0 16 5.7 0.0 6.4 7 0 0 7 7 7 1 NHL repeat Lactonase PF10282.4 KFP02560.1 - 0.058 12.4 0.0 30 3.5 0.0 4.3 5 0 0 5 5 5 0 Lactonase, 7-bladed beta-propeller Methyltransf_12 PF08242.7 KFP02560.1 - 0.093 13.2 0.3 2.3e+02 2.3 0.0 5.4 5 2 1 6 6 6 0 Methyltransferase domain Mucin PF01456.12 KFP02561.1 - 0.021 14.5 18.7 0.064 13.0 12.9 1.7 1 1 0 1 1 1 0 Mucin-like glycoprotein Toxin_3 PF00537.13 KFP02561.1 - 0.074 12.9 0.8 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain SET PF00856.23 KFP02562.1 - 4.7e-11 43.2 0.2 4.7e-11 43.2 0.1 3.0 3 2 0 3 3 3 1 SET domain Choline_kinase PF01633.15 KFP02563.1 - 3.1e-77 258.8 0.1 4.2e-77 258.4 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFP02563.1 - 1.5e-11 44.4 0.0 2.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFP02563.1 - 2.6e-08 33.3 0.3 1.1e-07 31.3 0.2 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase Endonuc_BglI PF14562.1 KFP02563.1 - 0.028 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglI LRR_6 PF13516.1 KFP02564.1 - 2.9e-32 107.0 61.9 0.00027 20.6 0.2 14.4 15 0 0 15 15 15 11 Leucine Rich repeat LRR_4 PF12799.2 KFP02564.1 - 3.5e-21 74.3 41.0 0.00011 21.7 0.2 9.0 7 3 0 7 7 7 7 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KFP02564.1 - 2.3e-13 47.9 38.8 1.8 9.1 0.0 13.6 14 0 0 14 14 14 5 Leucine rich repeat LRR_1 PF00560.28 KFP02564.1 - 3.1e-10 38.6 40.6 1.1 9.5 0.3 13.3 14 1 0 14 14 14 3 Leucine Rich Repeat LRR_8 PF13855.1 KFP02564.1 - 1.2e-05 24.9 37.9 0.0016 18.1 1.6 8.1 4 3 4 8 8 8 6 Leucine rich repeat RabGAP-TBC PF00566.13 KFP02565.1 - 3.1e-54 183.6 5.5 4.4e-54 183.1 3.8 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ras PF00071.17 KFP02566.1 - 1.8e-58 196.4 0.0 2.1e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP02566.1 - 3.6e-20 72.6 0.0 4.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP02566.1 - 9.2e-10 38.0 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP02566.1 - 1.8e-07 30.7 0.1 9.3e-07 28.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP02566.1 - 1.1e-05 25.3 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP02566.1 - 0.0021 17.2 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFP02566.1 - 0.0032 16.7 0.0 0.026 13.8 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 KFP02566.1 - 0.021 14.9 0.1 0.43 10.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KFP02566.1 - 0.029 13.9 0.3 0.74 9.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KFP02566.1 - 0.034 13.5 0.3 0.073 12.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KFP02566.1 - 0.04 12.9 0.0 0.072 12.1 0.0 1.6 1 1 0 1 1 1 0 Septin DUF258 PF03193.11 KFP02566.1 - 0.05 12.7 0.1 0.063 12.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 KFP02566.1 - 0.071 12.0 0.1 1.4 7.7 0.0 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) G-alpha PF00503.15 KFP02566.1 - 0.12 10.9 0.0 4.2 5.9 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit CbiA PF01656.18 KFP02566.1 - 0.13 11.6 0.0 0.8 9.0 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 KFP02566.1 - 0.14 12.0 0.1 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ThiF PF00899.16 KFP02566.1 - 0.18 11.6 0.5 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 ThiF family AAA_17 PF13207.1 KFP02566.1 - 0.29 11.9 1.1 28 5.5 0.7 2.6 2 1 0 2 2 2 0 AAA domain LRR_4 PF12799.2 KFP02567.1 - 3e-18 65.0 11.8 1.1e-09 37.6 0.1 3.9 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP02567.1 - 1.1e-10 41.1 8.2 0.0002 21.0 0.2 3.6 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KFP02567.1 - 7.7e-06 25.2 15.4 0.21 11.7 0.1 5.7 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 KFP02567.1 - 1.3e-05 24.7 16.1 0.071 13.2 0.4 5.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 KFP02567.1 - 0.00023 20.8 15.3 1.6 9.2 0.1 6.2 7 0 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 KFP02567.1 - 0.0029 17.2 1.8 0.0098 15.4 0.6 2.1 1 1 1 2 2 2 2 Leucine-rich repeat VWD PF00094.20 KFP02568.1 - 6.4e-29 101.1 0.7 6.4e-29 101.1 0.5 2.5 2 1 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 KFP02568.1 - 1.4e-18 66.8 3.3 1.4e-18 66.8 2.3 5.3 7 0 0 7 7 7 1 C8 domain VWC PF00093.13 KFP02568.1 - 2.1e-06 27.7 13.8 2.1e-06 27.7 9.6 8.8 7 2 2 9 9 9 3 von Willebrand factor type C domain TIL PF01826.12 KFP02568.1 - 0.00054 20.0 9.0 0.00054 20.0 6.2 10.5 8 4 1 9 9 9 1 Trypsin Inhibitor like cysteine rich domain VWD PF00094.20 KFP02569.1 - 5.5e-35 120.8 3.0 1.1e-34 119.9 2.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 KFP02569.1 - 1.9e-22 79.2 15.9 1.9e-22 79.2 11.0 2.2 2 0 0 2 2 2 1 C8 domain VWC PF00093.13 KFP02569.1 - 1.7e-05 24.8 7.2 1.7e-05 24.8 5.0 4.4 4 1 0 4 4 4 1 von Willebrand factor type C domain TIL PF01826.12 KFP02569.1 - 0.0007 19.6 5.4 0.0007 19.6 3.8 5.0 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.8 KFP02569.1 - 0.011 15.2 11.7 0.011 15.2 8.1 4.0 3 1 0 3 3 3 0 Pacifastin inhibitor (LCMII) VWD PF00094.20 KFP02570.1 - 3e-33 115.2 2.4 3e-33 115.2 1.6 2.8 2 1 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 KFP02570.1 - 2.8e-19 69.1 5.9 2.8e-19 69.1 4.1 4.8 4 1 0 4 4 4 1 C8 domain TIL PF01826.12 KFP02570.1 - 1.8e-05 24.7 12.3 1.8e-05 24.7 8.5 11.3 5 3 3 8 8 8 1 Trypsin Inhibitor like cysteine rich domain VWC PF00093.13 KFP02570.1 - 4.8e-05 23.3 33.9 0.00054 20.0 7.5 9.0 6 3 1 7 7 7 4 von Willebrand factor type C domain VWD PF00094.20 KFP02571.1 - 4.2e-31 108.2 1.8 4.2e-31 108.2 1.2 2.6 2 1 0 2 2 2 1 von Willebrand factor type D domain C8 PF08742.6 KFP02571.1 - 7.1e-23 80.6 14.1 7.1e-23 80.6 9.8 2.7 3 0 0 3 3 3 1 C8 domain VWC PF00093.13 KFP02571.1 - 7.1e-05 22.8 7.9 7.1e-05 22.8 5.5 4.2 4 1 0 4 4 4 1 von Willebrand factor type C domain TIL PF01826.12 KFP02571.1 - 0.001 19.1 6.0 0.001 19.1 4.1 4.7 4 1 0 4 4 4 1 Trypsin Inhibitor like cysteine rich domain Pacifastin_I PF05375.8 KFP02571.1 - 0.0018 17.7 14.6 0.0018 17.7 10.1 3.9 3 2 0 3 3 3 1 Pacifastin inhibitor (LCMII) VWD PF00094.20 KFP02572.1 - 7.2e-27 94.5 0.2 9.8e-27 94.0 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.6 KFP02572.1 - 4.5e-19 68.4 8.4 9e-19 67.5 5.8 1.5 1 0 0 1 1 1 1 C8 domain VWD PF00094.20 KFP02573.1 - 1.6e-79 265.6 10.9 3.3e-28 98.8 0.6 3.7 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.6 KFP02573.1 - 6.5e-47 157.6 37.6 1.3e-21 76.6 8.2 5.9 6 0 0 6 6 6 3 C8 domain TIL PF01826.12 KFP02573.1 - 1.4e-17 63.5 59.0 5.5e-11 42.4 12.9 9.5 8 2 1 9 9 9 3 Trypsin Inhibitor like cysteine rich domain VWC PF00093.13 KFP02573.1 - 6.8e-06 26.0 19.5 1.1e-05 25.3 2.6 9.5 7 4 1 8 8 8 2 von Willebrand factor type C domain Adaptin_N PF01602.15 KFP02574.1 - 9.1e-146 486.2 4.4 1.1e-145 485.9 3.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KFP02574.1 - 1.7e-44 150.3 0.0 4.7e-44 148.9 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KFP02574.1 - 1.8e-22 79.7 0.3 3.7e-22 78.8 0.2 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.2 KFP02574.1 - 8.4e-07 29.0 0.3 0.00042 20.1 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFP02574.1 - 2e-05 24.8 3.9 0.009 16.2 0.1 4.6 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 KFP02574.1 - 0.0014 18.5 2.5 14 6.0 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat RIX1 PF08167.7 KFP02574.1 - 0.0091 15.6 0.3 0.59 9.8 0.0 3.1 2 1 2 4 4 4 1 rRNA processing/ribosome biogenesis M11L PF11099.3 KFP02574.1 - 0.027 14.2 1.8 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Apoptosis regulator M11L like AP4E_app_platf PF14807.1 KFP02574.1 - 0.05 13.8 0.7 0.22 11.7 0.0 2.5 3 0 0 3 3 3 0 Adaptin AP4 complex epsilon appendage platform TIP120 PF08623.5 KFP02574.1 - 0.072 12.6 0.6 12 5.4 0.1 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Glyco_hydro_18 PF00704.23 KFP02575.1 - 1.6e-21 77.1 0.0 1.9e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Tetraspannin PF00335.15 KFP02576.1 - 1.5e-40 138.8 15.2 1.7e-40 138.6 10.6 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 KFP02576.1 - 0.0025 17.7 7.2 0.003 17.4 5.0 1.4 1 1 0 1 1 1 1 CD20-like family GP38 PF05268.6 KFP02576.1 - 0.036 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 TMEM192 PF14802.1 KFP02576.1 - 0.086 11.6 0.4 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 TMEM192 family Claudin_2 PF13903.1 KFP02576.1 - 1.3 8.7 9.6 0.067 12.8 2.6 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RNA_pol_N PF01194.12 KFP02577.1 - 1.7e-30 104.7 0.3 1.9e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KFP02577.1 - 0.096 12.7 0.3 0.16 12.0 0.2 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Tetraspannin PF00335.15 KFP02578.1 - 1.8e-57 194.1 16.6 2.1e-57 193.9 11.5 1.0 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 KFP02578.1 - 0.00057 19.8 6.6 0.00057 19.8 4.6 2.2 2 1 0 2 2 2 1 CD20-like family DUF4199 PF13858.1 KFP02578.1 - 0.0011 18.8 0.8 0.0011 18.8 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) AA_permease_2 PF13520.1 KFP02578.1 - 0.0056 15.2 2.4 0.0056 15.2 1.6 1.5 2 0 0 2 2 2 1 Amino acid permease Baculo_11_kDa PF06143.6 KFP02578.1 - 0.0057 15.9 4.1 8.1 5.8 0.2 3.2 3 0 0 3 3 3 2 Baculovirus 11 kDa family DUF4064 PF13273.1 KFP02578.1 - 0.04 14.0 7.1 3.8 7.6 1.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF843 PF05814.6 KFP02578.1 - 0.065 13.0 0.7 0.17 11.7 0.5 1.7 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) zf-DHHC PF01529.15 KFP02578.1 - 0.076 12.3 0.0 0.076 12.3 0.0 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase Chordopox_A13L PF05961.6 KFP02578.1 - 0.094 12.6 0.5 0.094 12.6 0.4 2.7 3 0 0 3 3 2 0 Chordopoxvirus A13L protein DUF4500 PF14937.1 KFP02578.1 - 0.14 12.0 2.3 6.6 6.6 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4500) DUF3185 PF11381.3 KFP02578.1 - 0.42 10.4 5.3 5.4 6.8 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF4405 PF14358.1 KFP02578.1 - 0.73 10.0 5.7 12 6.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Claudin_2 PF13903.1 KFP02578.1 - 1.5 8.5 14.4 0.025 14.2 2.7 2.6 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction ATP_synt_H PF05493.8 KFP02578.1 - 2 8.5 7.8 0.83 9.7 1.5 2.7 1 1 1 2 2 2 0 ATP synthase subunit H DUF975 PF06161.6 KFP02578.1 - 3.4 7.3 11.1 0.086 12.5 2.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF975) DUF3592 PF12158.3 KFP02578.1 - 4 7.2 9.8 5.7 6.7 4.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) Ras PF00071.17 KFP02579.1 - 3.9e-49 166.1 0.0 4.3e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP02579.1 - 9.8e-21 74.4 0.0 1.4e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP02579.1 - 9.2e-14 51.0 0.0 1.1e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP02579.1 - 8.5e-08 31.6 0.0 9.9e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP02579.1 - 2.9e-07 30.1 0.0 8.3e-07 28.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP02579.1 - 5.3e-07 29.5 0.0 6.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP02579.1 - 0.002 17.3 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_P4 PF11602.3 KFP02579.1 - 0.013 14.4 0.1 0.059 12.3 0.0 1.8 2 0 0 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 SRPRB PF09439.5 KFP02579.1 - 0.015 14.4 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFP02579.1 - 0.025 14.7 0.1 0.27 11.3 0.0 2.5 1 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KFP02579.1 - 0.028 14.2 0.1 3.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 KFP02579.1 - 0.041 13.6 0.2 0.086 12.5 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KFP02579.1 - 0.055 13.3 0.1 0.066 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFP02579.1 - 0.1 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 KFP02579.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain EF-hand_7 PF13499.1 KFP02580.1 - 1.3e-07 31.6 0.3 6.6e-06 26.1 0.1 3.4 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP02580.1 - 2.2e-07 30.1 0.1 0.0055 16.4 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFP02580.1 - 1.8e-06 26.8 0.8 0.033 13.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFP02580.1 - 0.00031 20.3 0.1 0.001 18.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP02580.1 - 0.12 11.8 0.1 2.8 7.4 0.0 2.7 2 0 0 2 2 2 0 EF hand Ribosomal_60s PF00428.14 KFP02581.1 - 4.3e-07 30.2 0.1 5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein LRR_8 PF13855.1 KFP02582.1 - 1.7e-16 59.6 23.3 4.1e-07 29.6 1.1 4.9 3 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFP02582.1 - 5.5e-16 57.7 22.7 0.00066 19.2 0.5 6.8 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) Death PF00531.17 KFP02582.1 - 3.7e-14 52.2 0.0 9.3e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Death domain LRR_1 PF00560.28 KFP02582.1 - 9.1e-11 40.2 32.8 0.033 14.1 0.2 9.1 8 1 1 9 9 9 5 Leucine Rich Repeat Peptidase_S68 PF10461.4 KFP02582.1 - 2.3e-08 33.6 6.4 1e-07 31.5 1.0 2.7 2 0 0 2 2 2 1 Peptidase S68 ZU5 PF00791.15 KFP02582.1 - 2.7e-06 26.9 0.3 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 ZU5 domain LRR_7 PF13504.1 KFP02582.1 - 0.00022 20.9 31.2 2.1 8.9 0.2 9.3 8 2 0 8 8 8 4 Leucine rich repeat LRR_6 PF13516.1 KFP02582.1 - 0.018 15.0 23.8 1.7 8.9 0.4 7.3 7 1 0 7 7 7 0 Leucine Rich repeat Mito_carr PF00153.22 KFP02583.1 - 5.7e-66 218.2 0.7 1.9e-23 81.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein IRF-3 PF10401.4 KFP02584.1 - 6.7e-47 159.3 0.6 9.2e-47 158.9 0.4 1.2 1 0 0 1 1 1 1 Interferon-regulatory factor 3 IRF PF00605.12 KFP02584.1 - 4e-37 126.3 0.2 6.6e-37 125.6 0.2 1.3 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Aida_N PF08910.5 KFP02585.1 - 0.092 12.9 0.4 8.6 6.6 0.0 2.6 1 1 1 2 2 2 0 Aida N-terminus RA PF00788.18 KFP02586.1 - 1.8e-10 41.1 0.1 6.7e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TGS PF02824.16 KFP02586.1 - 0.05 13.4 0.0 15 5.4 0.0 2.3 2 0 0 2 2 2 0 TGS domain AAA_13 PF13166.1 KFP02586.1 - 0.11 10.9 11.9 0.14 10.5 8.2 1.1 1 0 0 1 1 1 0 AAA domain Cauli_DNA-bind PF03310.8 KFP02586.1 - 0.14 12.0 1.2 0.34 10.7 0.8 1.8 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein ATG16 PF08614.6 KFP02586.1 - 0.77 9.5 25.9 0.84 9.4 14.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec20 PF03908.8 KFP02586.1 - 0.88 9.3 4.7 0.73 9.5 1.2 2.4 2 1 1 3 3 3 0 Sec20 DUF1664 PF07889.7 KFP02586.1 - 0.88 9.3 5.5 0.43 10.3 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cas_CT1975 PF09344.5 KFP02586.1 - 1.1 8.5 7.1 1.7 7.9 4.9 1.2 1 0 0 1 1 1 0 CT1975-like protein Reo_sigmaC PF04582.7 KFP02586.1 - 1.1 8.3 3.6 1.7 7.7 1.8 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Sipho_Gp157 PF05565.6 KFP02586.1 - 2.3 7.8 11.5 0.41 10.2 4.2 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 Carn_acyltransf PF00755.15 KFP02587.1 - 3.6e-210 699.0 0.0 4.2e-210 698.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Galanin PF01296.13 KFP02588.1 - 1.7e-22 78.8 1.9 2.8e-22 78.2 1.3 1.4 1 0 0 1 1 1 1 Galanin GMAP PF06540.6 KFP02588.1 - 1.1e-18 66.6 0.0 1.4e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Galanin message associated peptide (GMAP) SAPS PF04499.10 KFP02589.1 - 8.6e-106 354.3 13.1 1.8e-66 224.7 5.8 4.0 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein FliC PF12445.3 KFP02589.1 - 0.0098 16.0 3.8 0.027 14.6 2.6 1.7 1 0 0 1 1 1 1 Flagellin protein Atx10homo_assoc PF09759.4 KFP02589.1 - 0.038 13.7 3.8 0.054 13.2 0.4 2.8 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DJ-1_PfpI PF01965.19 KFP02590.1 - 2.2e-11 43.4 0.1 2.8e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.1 KFP02590.1 - 0.023 13.6 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain dUTPase PF00692.14 KFP02591.1 - 1.4e-17 63.3 0.0 1.9e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP02591.1 - 0.0018 18.1 0.0 0.0088 15.9 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease S_100 PF01023.14 KFP02595.1 - 4.7e-18 64.2 0.0 8.3e-18 63.4 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFP02595.1 - 5.6e-08 31.5 1.4 4.9e-06 25.4 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFP02595.1 - 1.9e-06 27.3 0.6 0.00016 21.2 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 KFP02595.1 - 2.2e-06 27.7 0.1 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP02595.1 - 2.7e-06 26.4 1.1 6.2e-05 22.1 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KFP02595.1 - 0.00013 21.5 0.3 0.17 11.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain tRNA_bind_2 PF13725.1 KFP02595.1 - 0.013 15.6 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain EF-hand_4 PF12763.2 KFP02595.1 - 0.042 13.6 0.1 0.054 13.2 0.1 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_like PF09279.6 KFP02595.1 - 0.048 13.6 0.3 0.093 12.7 0.2 1.5 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like HLH PF00010.21 KFP02596.1 - 6.4e-19 67.3 0.3 6.4e-19 67.3 0.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RRXRR PF14239.1 KFP02596.1 - 0.19 11.1 2.4 0.24 10.7 1.6 1.2 1 0 0 1 1 1 0 RRXRR protein Strabismus PF06638.6 KFP02597.1 - 2.8e-220 731.8 5.5 5.8e-146 486.7 0.0 2.6 2 1 0 2 2 2 2 Strabismus protein IL28A PF15177.1 KFP02597.1 - 0.055 12.9 0.1 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 Interleukin-28A V-set PF07686.12 KFP02598.1 - 8.8e-09 35.2 0.0 1.9e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP02598.1 - 9.7e-05 22.4 0.5 0.018 15.1 0.2 2.4 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP02598.1 - 0.0061 16.3 0.3 0.054 13.3 0.0 2.6 2 2 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 KFP02598.1 - 0.0068 16.5 0.5 0.074 13.1 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain Herpes_gI PF01688.12 KFP02598.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Ig_3 PF13927.1 KFP02598.1 - 0.16 12.5 4.7 26 5.4 0.0 3.4 2 2 0 2 2 2 0 Immunoglobulin domain Ig_3 PF13927.1 KFP02599.1 - 0.0077 16.7 4.8 0.083 13.4 3.4 2.2 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFP02600.1 - 3.9e-28 97.4 2.4 4.6e-10 39.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFP02600.1 - 1.2e-24 85.9 1.0 4.7e-08 32.7 0.0 3.6 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP02600.1 - 1.9e-22 79.5 0.7 5.6e-06 26.7 0.1 3.6 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP02600.1 - 3.5e-20 71.8 0.7 1.6e-05 24.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 KFP02600.1 - 1.4e-18 66.5 5.6 2e-18 66.0 0.4 2.9 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain V-set PF07686.12 KFP02600.1 - 1.1e-13 51.0 5.5 2.7e-08 33.6 0.0 4.3 2 1 1 3 3 3 2 Immunoglobulin V-set domain C1-set PF07654.10 KFP02600.1 - 2e-08 34.1 2.6 4.4e-08 33.0 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin C1-set domain C2-set PF05790.10 KFP02600.1 - 0.021 14.7 5.3 2.8 7.9 0.6 3.6 4 1 0 4 4 4 0 Immunoglobulin C2-set domain Syndecan PF01034.15 KFP02600.1 - 0.3 10.7 1.0 0.97 9.1 0.0 2.4 3 0 0 3 3 3 0 Syndecan domain I-set PF07679.11 KFP02601.1 - 1.6e-40 136.8 0.0 3.7e-12 45.9 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP02601.1 - 3.9e-39 132.6 2.2 5.7e-10 39.1 0.1 5.5 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFP02601.1 - 4.1e-29 100.8 5.7 6e-07 29.8 0.1 6.3 6 0 0 6 6 6 3 Immunoglobulin domain ig PF00047.20 KFP02601.1 - 1.1e-24 86.3 0.1 5.3e-08 32.8 0.0 5.6 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.16 KFP02601.1 - 3.3e-21 75.1 0.0 1.7e-10 40.8 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain V-set PF07686.12 KFP02601.1 - 8.4e-17 61.1 0.2 0.00023 21.0 0.0 5.8 6 2 0 6 6 6 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP02601.1 - 2.1e-06 27.5 0.5 1.5 8.7 0.0 3.8 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP02601.1 - 0.029 12.6 0.2 1.2 7.2 0.0 2.8 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E C2-set PF05790.10 KFP02601.1 - 0.041 13.8 0.2 1.1 9.2 0.0 3.1 3 0 0 3 3 3 0 Immunoglobulin C2-set domain V-set_CD47 PF08204.6 KFP02601.1 - 0.065 12.9 0.1 4.4 7.0 0.0 3.2 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain CH PF00307.26 KFP02602.1 - 8.8e-14 51.4 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.13 KFP02602.1 - 3e-13 48.8 4.6 3e-13 48.8 3.2 2.2 2 0 0 2 2 2 1 Calponin family repeat CDC24 PF06395.6 KFP02602.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.3 KFP02602.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Trichoplein PF13868.1 KFP02603.1 - 0.0031 15.9 6.2 0.0036 15.7 4.3 1.1 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin Kri1 PF05178.7 KFP02603.1 - 0.11 12.8 1.6 0.11 12.7 1.1 1.2 1 0 0 1 1 1 0 KRI1-like family Porin_3 PF01459.17 KFP02604.1 - 1.4e-35 122.8 0.0 1.7e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH PF00443.24 KFP02605.1 - 3.8e-14 52.4 0.1 4.5e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP02605.1 - 2.4e-07 30.4 0.1 2.8e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.2 KFP02605.1 - 0.023 14.5 2.9 1 9.2 0.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 KFP02605.1 - 0.11 12.4 2.1 0.2 11.5 1.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger DNA_RNApol_7kD PF03604.8 KFP02605.1 - 0.36 10.3 3.1 0.97 8.9 0.3 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit XPA_N PF01286.13 KFP02605.1 - 0.81 9.4 5.6 0.43 10.2 0.3 2.6 2 0 0 2 2 2 0 XPA protein N-terminal WD40 PF00400.27 KFP02608.1 - 8.2e-14 50.8 0.1 9.5e-08 31.6 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1675 PF07897.6 KFP02608.1 - 0.015 15.2 6.5 0.024 14.5 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SAPS PF04499.10 KFP02608.1 - 0.058 12.0 2.8 0.062 11.9 1.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 KFP02608.1 - 0.07 10.8 2.0 0.064 10.9 1.4 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 KFP02608.1 - 1.5 8.2 12.6 2.4 7.5 8.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO SDA1 PF05285.7 KFP02608.1 - 3 7.0 24.9 3.9 6.6 17.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KFP02608.1 - 3.8 5.3 25.6 4.8 4.9 17.7 1.0 1 0 0 1 1 1 0 Nop14-like family AUX_IAA PF02309.11 KFP02608.1 - 4.7 6.9 10.0 7.1 6.3 7.0 1.2 1 0 0 1 1 1 0 AUX/IAA family Prog_receptor PF02161.10 KFP02608.1 - 7 5.3 12.8 11 4.7 8.9 1.2 1 0 0 1 1 1 0 Progesterone receptor Daxx PF03344.10 KFP02608.1 - 7.8 4.8 24.8 11 4.3 17.2 1.2 1 0 0 1 1 1 0 Daxx Family DED PF01335.16 KFP02609.1 - 2.7e-20 72.2 0.1 3.4e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Death effector domain DUF4381 PF14316.1 KFP02609.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1281 PF06924.6 KFP02609.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF455 PF04305.9 KFP02609.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) E1-E2_ATPase PF00122.15 KFP02610.1 - 5.2e-61 205.6 1.2 8.1e-61 204.9 0.9 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFP02610.1 - 9.3e-22 78.4 0.7 1.8e-15 57.9 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KFP02610.1 - 2.8e-20 72.6 0.0 2.8e-20 72.6 0.0 1.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KFP02610.1 - 1.5e-12 47.3 0.0 3.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFP02610.1 - 5.6e-10 39.7 0.4 2.5e-05 24.5 0.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFP02610.1 - 0.00061 19.4 0.4 0.0012 18.4 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sigma70_r4 PF04545.11 KFP02610.1 - 0.023 13.9 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 IRK PF01007.15 KFP02611.1 - 7.8e-155 514.7 0.2 8.7e-155 514.6 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP02611.1 - 0.00043 19.9 6.5 0.0015 18.1 4.5 2.0 1 1 0 1 1 1 1 Ion channel IRK PF01007.15 KFP02612.1 - 1.1e-144 481.3 0.1 1.2e-144 481.2 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP02612.1 - 0.023 14.3 3.9 0.053 13.2 2.6 1.7 1 1 0 1 1 1 0 Ion channel Sugar_tr PF00083.19 KFP02613.1 - 3.8e-28 98.2 10.7 4.9e-28 97.9 7.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP02613.1 - 4.3e-20 71.7 29.5 4.3e-20 71.7 20.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PHD PF00628.24 KFP02614.1 - 1.3e-07 31.1 10.3 1.3e-07 31.1 7.2 2.1 2 1 0 2 2 2 1 PHD-finger Inositol_P PF00459.20 KFP02615.1 - 4e-51 173.8 0.5 4.6e-51 173.7 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Cation_efflux PF01545.16 KFP02616.1 - 3.4e-71 239.6 0.0 3.9e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Cation efflux family NicO PF03824.11 KFP02616.1 - 0.006 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 High-affinity nickel-transport protein A2M_comp PF07678.9 KFP02617.1 - 4.7e-74 248.7 0.9 9.9e-74 247.6 0.6 1.6 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 KFP02617.1 - 8e-33 111.8 1.0 4.3e-32 109.5 0.2 2.7 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 KFP02617.1 - 7.5e-25 87.2 2.4 8.9e-24 83.8 0.0 3.6 3 1 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M_recep PF07677.9 KFP02617.1 - 2.6e-24 85.1 0.1 1.4e-22 79.6 0.0 3.0 2 0 0 2 2 2 1 A-macroglobulin receptor NTR PF01759.16 KFP02617.1 - 3e-22 78.2 0.1 1.3e-21 76.2 0.1 2.2 1 0 0 1 1 1 1 UNC-6/NTR/C345C module A2M_N PF01835.14 KFP02617.1 - 1.5e-18 66.8 3.3 1.7e-16 60.2 0.0 4.6 5 0 0 5 5 5 1 MG2 domain Thiol-ester_cl PF10569.4 KFP02617.1 - 2.1e-14 52.4 0.0 4.5e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region ANATO PF01821.13 KFP02617.1 - 8.7e-12 44.9 8.4 2e-11 43.8 5.8 1.7 1 0 0 1 1 1 1 Anaphylotoxin-like domain Prenyltrans_2 PF13249.1 KFP02617.1 - 2.5e-09 37.5 0.6 1.2e-05 25.6 0.0 3.0 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFP02617.1 - 5.2e-05 23.2 0.0 0.0046 16.9 0.0 3.0 1 1 1 2 2 2 1 Prenyltransferase-like Band_7 PF01145.20 KFP02618.1 - 7.4e-28 97.6 1.5 9.8e-28 97.2 1.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFP02618.1 - 0.012 15.1 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Phlebovirus_G1 PF07243.6 KFP02618.1 - 0.057 11.5 0.1 0.079 11.0 0.0 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 DUF4476 PF14771.1 KFP02619.1 - 2.8e-26 91.3 0.8 6.3e-22 77.4 0.2 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4476) NHL PF01436.16 KFP02620.1 - 1.6e-15 56.1 4.1 4.6e-08 32.6 0.0 5.4 5 0 0 5 5 5 4 NHL repeat SGL PF08450.7 KFP02620.1 - 6.5e-06 25.7 0.3 0.062 12.6 0.0 4.0 3 1 2 5 5 5 2 SMP-30/Gluconolaconase/LRE-like region Lipase_GDSL_2 PF13472.1 KFP02621.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MBOAT PF03062.14 KFP02622.1 - 4.8e-34 117.9 9.6 6.4e-34 117.5 6.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family KAP_NTPase PF07693.9 KFP02623.1 - 1.6e-105 352.7 0.1 2.2e-105 352.2 0.1 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_2 PF12796.2 KFP02623.1 - 7.1e-90 295.5 3.7 2.2e-18 66.3 0.0 5.7 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFP02623.1 - 3e-86 279.2 3.9 3.1e-09 36.1 0.0 12.5 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 KFP02623.1 - 3.1e-70 231.4 10.5 1.3e-10 41.5 0.0 9.4 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP02623.1 - 1.2e-68 225.5 8.9 8.9e-13 48.0 0.2 10.6 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02623.1 - 7.7e-56 180.4 3.9 5.2e-06 26.2 0.0 12.6 12 0 0 12 12 12 10 Ankyrin repeat NACHT PF05729.7 KFP02623.1 - 0.0004 20.0 0.2 0.044 13.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain SAM_1 PF00536.25 KFP02623.1 - 0.0037 17.4 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4271 PF14093.1 KFP02623.1 - 0.12 11.9 9.2 0.02 14.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF2207 PF09972.4 KFP02623.1 - 0.33 9.4 6.5 0.14 10.6 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ABC2_membrane_2 PF12679.2 KFP02623.1 - 2.8 6.7 8.3 0.22 10.3 0.5 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein HLH PF00010.21 KFP02624.1 - 6.7e-14 51.3 0.4 1.1e-13 50.6 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TLV_coat PF00429.14 KFP02625.1 - 0.048 12.1 0.2 0.054 11.9 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Gon7 PF08738.5 KFP02625.1 - 0.1 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Gon7 family Sulfotransfer_1 PF00685.22 KFP02627.1 - 1.3e-38 132.8 0.3 1.8e-38 132.3 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP02627.1 - 0.0007 20.5 0.6 0.0017 19.3 0.4 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 KFP02627.1 - 0.0017 18.1 0.5 0.0049 16.5 0.1 1.8 2 0 0 2 2 2 1 Sulfotransferase family Proho_convert PF12177.3 KFP02627.1 - 0.018 14.6 0.1 0.068 12.7 0.0 2.0 1 0 0 1 1 1 0 Prohormone convertase enzyme zf-H2C2_2 PF13465.1 KFP02628.1 - 2e-05 24.6 0.6 2e-05 24.6 0.4 6.2 6 0 0 6 6 6 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFP02628.1 - 0.00016 21.6 23.2 0.011 15.8 1.0 5.0 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFP02628.1 - 0.043 14.1 30.1 1.5 9.3 0.1 5.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type WD40 PF00400.27 KFP02629.1 - 3.4e-63 207.4 13.6 5.4e-11 41.9 0.0 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat eIF2A PF08662.6 KFP02629.1 - 7e-12 45.4 0.6 0.0054 16.4 0.0 5.1 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFP02629.1 - 0.00025 19.0 0.0 0.017 12.9 0.0 2.8 2 1 0 3 3 3 1 IKI3 family BBS2_Mid PF14783.1 KFP02629.1 - 0.0011 18.7 0.0 0.019 14.7 0.0 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 KFP02629.1 - 0.0063 16.0 0.3 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 PQQ enzyme repeat Apc4_WD40 PF12894.2 KFP02629.1 - 0.025 14.0 0.0 1.7 8.1 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.1 KFP02629.1 - 0.058 12.8 0.2 3.1 7.1 0.0 2.7 2 1 0 2 2 2 0 PQQ-like domain Sugar_tr PF00083.19 KFP02630.1 - 5.4e-106 354.8 27.8 6.3e-106 354.6 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP02630.1 - 4e-29 101.4 42.7 1.9e-22 79.4 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.16 KFP02631.1 - 3.3e-84 282.0 15.8 4.2e-84 281.7 11.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02631.1 - 2.6e-12 46.4 12.6 2.2e-11 43.3 8.7 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP02631.1 - 4.7e-06 25.9 9.9 4.7e-06 25.9 6.9 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx zf-LITAF-like PF10601.4 KFP02631.1 - 0.046 13.5 2.0 0.24 11.2 1.4 2.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Otopetrin PF03189.8 KFP02632.1 - 5.5e-38 131.1 16.8 3.6e-18 65.8 2.5 3.2 2 1 0 3 3 3 3 Otopetrin E1-E2_ATPase PF00122.15 KFP02632.1 - 0.073 12.0 1.8 0.12 11.3 1.2 1.3 1 0 0 1 1 1 0 E1-E2 ATPase zf-LYAR PF08790.6 KFP02634.1 - 5.3e-14 51.5 1.6 5.3e-14 51.5 1.1 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger C1_4 PF07975.7 KFP02634.1 - 0.43 10.6 9.1 1.4 9.0 6.3 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain IBR PF01485.16 KFP02634.1 - 0.88 9.4 12.2 2.4 8.1 8.5 1.7 1 0 0 1 1 1 0 IBR domain Mut7-C PF01927.11 KFP02634.1 - 2.8 7.9 8.7 12 5.9 6.0 2.1 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.1 KFP02635.1 - 4.6e-49 162.3 47.9 8.7e-09 35.2 3.0 8.5 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFP02635.1 - 3.5e-36 121.3 51.9 3.3e-06 27.1 0.8 7.9 7 0 0 7 7 7 7 Zinc finger, C2H2 type BTB PF00651.26 KFP02635.1 - 7.1e-26 90.3 0.8 1.4e-25 89.4 0.6 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KFP02635.1 - 9.9e-23 78.7 44.7 0.00016 21.7 0.7 7.8 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP02635.1 - 3.2e-18 64.9 43.4 0.00023 20.9 0.3 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP02635.1 - 9e-18 63.8 33.2 0.00059 19.9 0.5 8.2 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP02635.1 - 5e-10 39.2 43.6 0.0047 17.0 0.5 8.5 9 0 0 9 9 9 5 Zinc-finger of C2H2 type GAGA PF09237.6 KFP02635.1 - 0.00013 21.4 20.6 0.18 11.4 0.1 6.4 3 2 4 7 7 7 3 GAGA factor zf-BED PF02892.10 KFP02635.1 - 0.017 14.8 1.5 0.017 14.8 1.0 6.5 1 1 5 6 6 6 0 BED zinc finger BolA PF01722.13 KFP02635.1 - 0.2 11.6 2.7 19 5.2 0.1 4.0 2 2 0 2 2 2 0 BolA-like protein zf-C2HC_2 PF13913.1 KFP02635.1 - 0.7 9.6 31.7 0.69 9.6 0.3 7.1 7 0 0 7 7 7 0 zinc-finger of a C2HC-type Elf1 PF05129.8 KFP02635.1 - 3.7 7.2 24.1 0.57 9.9 2.9 4.3 2 2 2 4 4 4 0 Transcription elongation factor Elf1 like Calcyon PF06387.6 KFP02636.1 - 8.8e-96 318.6 0.2 9.8e-96 318.4 0.2 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) MgsA_C PF12002.3 KFP02636.1 - 0.023 14.4 0.2 0.039 13.6 0.2 1.3 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DUF2448 PF10476.4 KFP02636.1 - 0.023 14.1 0.1 0.055 12.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) CPW_WPC PF09717.5 KFP02636.1 - 0.091 13.3 0.1 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Syntaxin-18_N PF10496.4 KFP02637.1 - 4.2e-24 84.1 0.3 1.4e-23 82.5 0.2 1.9 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus DUF1043 PF06295.7 KFP02637.1 - 0.038 13.6 0.5 0.038 13.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) SNARE PF05739.14 KFP02637.1 - 0.066 12.8 4.5 0.16 11.6 3.1 1.7 1 0 0 1 1 1 0 SNARE domain TipAS PF07739.8 KFP02637.1 - 0.09 13.1 3.5 3.2 8.0 0.2 2.7 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Homeobox PF00046.24 KFP02638.1 - 4.7e-22 77.3 4.6 7.2e-22 76.7 3.2 1.3 1 0 0 1 1 1 1 Homeobox domain CYTL1 PF15153.1 KFP02639.1 - 3.7e-54 182.0 3.1 4e-54 181.9 2.2 1.0 1 0 0 1 1 1 1 Cytokine-like protein 1 PET PF06297.9 KFP02640.1 - 3e-43 145.7 1.2 5.1e-43 145.0 0.8 1.4 1 0 0 1 1 1 1 PET Domain LIM PF00412.17 KFP02640.1 - 6.4e-26 90.2 60.1 2.3e-13 49.9 4.9 4.9 4 2 0 4 4 4 3 LIM domain DUF499 PF04465.7 KFP02640.1 - 0.19 9.2 0.0 0.25 8.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF499) DUF3371 PF11851.3 KFP02641.1 - 1.8e-38 132.1 5.3 1.8e-38 132.1 3.7 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3371) HLH PF00010.21 KFP02641.1 - 1.4e-15 56.7 0.4 3.3e-15 55.5 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UPF0449 PF15136.1 KFP02641.1 - 5.2 7.3 7.6 7.5 6.8 1.4 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Lipase_GDSL_2 PF13472.1 KFP02642.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MDFI PF15316.1 KFP02643.1 - 3e-74 248.7 41.3 4.3e-74 248.2 28.6 1.2 1 0 0 1 1 1 1 MyoD family inhibitor Fork_head PF00250.13 KFP02644.1 - 2.6e-36 123.5 0.1 3.2e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Fork head domain Linker_histone PF00538.14 KFP02644.1 - 0.08 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 linker histone H1 and H5 family BssC_TutF PF08201.6 KFP02644.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 BssC/TutF protein CBM_21 PF03370.8 KFP02645.1 - 1.2e-27 96.1 0.2 2.5e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit RseC_MucC PF04246.7 KFP02647.1 - 0.061 12.8 1.6 0.064 12.8 1.1 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Tetraspannin PF00335.15 KFP02647.1 - 0.76 9.0 3.8 0.96 8.6 2.6 1.2 1 1 0 1 1 1 0 Tetraspanin family DUF3321 PF11968.3 KFP02648.1 - 4.6e-08 32.9 0.4 2.5e-05 23.9 0.2 2.1 1 1 1 2 2 2 2 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KFP02648.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C14 PF00656.17 KFP02649.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Caspase domain DUF4577 PF15145.1 KFP02650.1 - 8.9e-40 135.5 0.1 1e-39 135.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4577) CCSMST1 PF15013.1 KFP02650.1 - 0.0095 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 CCSMST1 family MscL PF01741.13 KFP02650.1 - 0.012 15.7 1.9 0.012 15.7 1.3 1.5 1 1 1 2 2 2 0 Large-conductance mechanosensitive channel, MscL Tetraspannin PF00335.15 KFP02650.1 - 0.013 14.7 0.2 0.017 14.3 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family Bap31 PF05529.7 KFP02650.1 - 0.015 14.7 0.3 0.018 14.4 0.2 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like BatD PF13584.1 KFP02650.1 - 0.025 13.1 0.0 0.028 13.0 0.0 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF2976 PF11190.3 KFP02650.1 - 0.072 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF912 PF06024.7 KFP02650.1 - 0.075 13.0 0.1 0.2 11.7 0.0 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2089 PF09862.4 KFP02650.1 - 0.091 12.5 0.5 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) DUF948 PF06103.6 KFP02650.1 - 0.094 12.5 0.6 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IFRD PF05004.8 KFP02651.1 - 2.6e-117 391.3 7.1 3.1e-117 391.0 4.9 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 KFP02651.1 - 3.5e-27 94.3 0.7 3.5e-27 94.3 0.5 2.1 2 0 0 2 2 2 1 Interferon-related protein conserved region HEAT PF02985.17 KFP02651.1 - 0.028 14.4 0.3 7.4 6.9 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat zf-C2H2_2 PF12756.2 KFP02652.1 - 8.4e-43 144.6 25.5 2.6e-24 85.2 5.2 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFP02652.1 - 4.2e-05 23.5 2.8 4.2e-05 23.5 1.9 4.4 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFP02652.1 - 0.00049 20.2 1.8 0.00049 20.2 1.2 5.3 5 1 0 5 5 5 2 Zinc finger, C2H2 type zf-BED PF02892.10 KFP02652.1 - 0.0024 17.5 2.0 0.0024 17.5 1.4 4.5 5 0 0 5 5 5 1 BED zinc finger zf-C2H2_4 PF13894.1 KFP02652.1 - 0.014 15.7 0.7 0.014 15.7 0.5 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger PyrI_C PF02748.10 KFP02652.1 - 0.017 14.5 0.6 0.017 14.5 0.4 4.1 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain VOMI PF03762.12 KFP02652.1 - 0.036 14.0 0.3 0.067 13.1 0.2 1.4 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) zf-met PF12874.2 KFP02652.1 - 0.051 13.8 1.2 0.051 13.8 0.9 4.0 5 1 0 5 5 5 0 Zinc-finger of C2H2 type YokU PF14122.1 KFP02652.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.0 4 0 0 4 4 4 0 YokU-like protein zf-H2C2_5 PF13909.1 KFP02652.1 - 0.15 12.3 0.2 0.15 12.3 0.1 5.1 5 1 0 5 5 5 0 C2H2-type zinc-finger domain DOCK-C2 PF14429.1 KFP02653.1 - 1.5e-49 168.1 0.0 1e-48 165.4 0.0 2.5 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KFP02653.1 - 5e-45 152.9 0.6 9.7e-45 152.0 0.4 1.4 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KFP02653.1 - 0.00076 18.8 0.0 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP02653.1 - 0.00084 18.7 0.1 0.0026 17.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFP02653.1 - 0.0025 17.3 0.0 0.0059 16.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_S24 PF00717.18 KFP02654.1 - 5.9e-10 38.6 0.3 1e-09 37.8 0.2 1.4 1 1 0 1 1 1 1 Peptidase S24-like DUF2798 PF11391.3 KFP02654.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) LRR_8 PF13855.1 KFP02655.1 - 2e-43 145.9 33.9 1.2e-13 50.5 3.0 6.9 2 1 5 8 8 8 7 Leucine rich repeat LRR_5 PF13306.1 KFP02655.1 - 3.9e-29 100.9 0.1 8.3e-10 38.4 0.0 3.4 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFP02655.1 - 2.9e-23 80.9 47.0 3.6e-05 23.2 0.7 7.8 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) I-set PF07679.11 KFP02655.1 - 5.6e-13 48.5 0.0 3.5e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFP02655.1 - 6.4e-10 37.6 35.3 1.8 8.9 0.0 12.2 12 0 0 12 12 12 5 Leucine Rich Repeat Ig_3 PF13927.1 KFP02655.1 - 4.2e-08 33.5 0.2 1.8e-07 31.5 0.2 2.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFP02655.1 - 5.5e-08 32.8 0.0 1.5e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 KFP02655.1 - 1.6e-07 31.3 0.1 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain ig PF00047.20 KFP02655.1 - 6.9e-07 29.3 0.1 2.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP02655.1 - 1.7e-05 24.7 0.2 7.1e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 Immunoglobulin V-set domain LRR_9 PF14580.1 KFP02655.1 - 0.00012 21.6 14.7 0.15 11.6 1.2 4.3 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 KFP02655.1 - 0.0041 17.0 27.9 5.3 7.6 0.1 10.1 11 0 0 11 11 10 1 Leucine rich repeat LRRCT PF01463.19 KFP02655.1 - 0.045 14.0 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain LRRNT PF01462.13 KFP02655.1 - 0.21 11.0 7.1 0.036 13.5 0.6 3.0 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain DnaJ PF00226.26 KFP02656.1 - 5.1e-29 99.8 2.3 7.6e-29 99.2 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain THAP PF05485.7 KFP02657.1 - 2.3e-16 59.7 0.3 4.8e-16 58.7 0.2 1.5 1 0 0 1 1 1 1 THAP domain CENP-R PF06729.7 KFP02657.1 - 0.25 11.0 3.3 0.72 9.5 0.2 2.4 2 0 0 2 2 2 0 Kinetochore component, CENP-R Trypsin PF00089.21 KFP02659.1 - 7.5e-49 166.2 0.0 8.4e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP02659.1 - 4.9e-05 22.7 0.1 5.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF2905 PF11146.3 KFP02659.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Sox_C_TAD PF12067.3 KFP02660.1 - 2e-51 174.9 12.3 2.8e-51 174.5 8.5 1.2 1 0 0 1 1 1 1 Sox C-terminal transactivation domain HMG_box PF00505.14 KFP02660.1 - 1e-07 32.1 0.3 1.8e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP02660.1 - 0.0032 17.8 0.1 0.0065 16.8 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain G-patch PF01585.18 KFP02661.1 - 1.3e-16 60.0 3.3 2.3e-16 59.3 2.3 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFP02661.1 - 1.2e-09 37.8 1.2 1.2e-09 37.8 0.8 1.8 2 0 0 2 2 2 1 DExH-box splicing factor binding site XK-related PF09815.4 KFP02662.1 - 1.8e-105 352.6 19.8 2.2e-105 352.3 13.7 1.1 1 0 0 1 1 1 1 XK-related protein Meleagrin PF08189.6 KFP02663.1 - 2.7e-24 84.3 14.7 3.3e-24 84.0 10.2 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family zf-MYND PF01753.13 KFP02663.1 - 0.028 14.2 3.5 0.028 14.2 2.4 1.7 1 1 0 1 1 1 0 MYND finger DIM PF08194.7 KFP02663.1 - 0.065 13.2 1.9 0.065 13.2 1.3 1.7 2 0 0 2 2 2 0 DIM protein Nodulin_late PF07127.6 KFP02663.1 - 0.66 10.1 5.3 4.3 7.5 3.4 2.1 1 1 1 2 2 2 0 Late nodulin protein Meleagrin PF08189.6 KFP02664.1 - 1.4e-25 88.4 17.2 1.7e-25 88.1 12.0 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family zf-MYND PF01753.13 KFP02664.1 - 0.048 13.5 4.0 0.048 13.5 2.8 1.8 1 1 0 1 1 1 0 MYND finger Meleagrin PF08189.6 KFP02665.1 - 1.5e-24 85.2 14.7 1.7e-24 84.9 10.2 1.1 1 0 0 1 1 1 1 Meleagrin/Cygnin family zf-MYND PF01753.13 KFP02665.1 - 2.6 7.9 12.2 1.3 9.0 6.6 1.8 1 1 0 1 1 1 0 MYND finger Myotub-related PF06602.9 KFP02666.1 - 9.8e-78 261.3 4.9 1.2e-77 261.1 3.4 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Hydrolase_6 PF13344.1 KFP02666.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Epimerase PF01370.16 KFP02667.1 - 5e-17 62.1 0.0 6.8e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFP02667.1 - 5.3e-08 31.9 0.0 8.6e-08 31.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFP02667.1 - 7.9e-08 31.5 0.0 1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFP02667.1 - 4.4e-05 22.5 0.0 0.00012 21.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFP02667.1 - 0.00011 21.2 0.0 0.0057 15.5 0.1 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFP02667.1 - 0.0011 18.9 0.1 0.0025 17.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFP02667.1 - 0.012 15.3 0.0 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 KR domain DUF3259 PF11652.3 KFP02669.1 - 6.8e-47 157.5 2.6 1.1e-46 156.8 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3259) LURAP PF14854.1 KFP02669.1 - 0.0022 17.6 0.3 0.004 16.8 0.2 1.5 1 0 0 1 1 1 1 Leucine rich adaptor protein IncA PF04156.9 KFP02669.1 - 0.025 14.1 1.1 0.028 13.9 0.2 1.5 1 1 0 1 1 1 0 IncA protein ERM PF00769.14 KFP02669.1 - 0.094 12.2 0.2 0.094 12.2 0.2 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2388 PF09498.5 KFP02669.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) DUF4530 PF15039.1 KFP02669.1 - 0.18 11.6 1.7 0.31 10.9 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4530) Dapper PF15268.1 KFP02669.1 - 0.22 10.2 2.5 0.21 10.3 1.1 1.3 1 1 0 1 1 1 0 Dapper Pkinase_Tyr PF07714.12 KFP02670.1 - 5.1e-64 215.8 0.0 6.6e-61 205.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFP02670.1 - 1.8e-29 102.6 0.0 2.8e-27 95.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SH2 PF00017.19 KFP02670.1 - 2.4e-26 91.3 0.1 4e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 SH2 domain SPRY PF00622.23 KFP02672.1 - 1.4e-18 67.1 0.3 2.6e-18 66.2 0.2 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.1 KFP02672.1 - 1e-08 34.7 13.6 1e-08 34.7 9.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Nefa_Nip30_N PF10187.4 KFP02673.1 - 3.7e-35 120.1 22.1 8.6e-35 118.9 15.3 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Herpes_capsid PF06112.6 KFP02673.1 - 0.81 9.7 6.1 1.5 8.8 4.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Copine PF07002.11 KFP02674.1 - 7.5e-61 204.1 0.0 1.6e-60 203.0 0.0 1.6 1 0 0 1 1 1 1 Copine C2 PF00168.25 KFP02674.1 - 1.3e-27 95.4 0.1 8.8e-13 47.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 KFP02674.1 - 3.6e-10 39.9 0.0 7.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Oxidored_q3 PF00499.15 KFP02675.1 - 2.3e-10 40.4 13.5 2.3e-10 40.4 9.4 1.2 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PSII PF00421.14 KFP02675.1 - 0.056 12.0 0.9 0.067 11.7 0.4 1.2 1 1 0 1 1 1 0 Photosystem II protein OAD_gamma PF04277.8 KFP02675.1 - 3.7 7.9 5.5 5.9 7.3 3.8 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2770 PF10968.3 KFP02675.1 - 6.4 6.5 10.2 1.2 8.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) LBP_BPI_CETP PF01273.20 KFP02676.1 - 2.6e-27 95.1 0.2 7.2e-27 93.7 0.0 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.12 KFP02676.1 - 3.6e-27 95.1 1.0 9.6e-26 90.4 0.2 2.2 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain ubiquitin PF00240.18 KFP02677.1 - 0.0024 17.2 1.1 0.0034 16.7 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin family Auxin_repressed PF05564.7 KFP02677.1 - 0.053 14.1 0.1 0.095 13.3 0.1 1.4 1 0 0 1 1 1 0 Dormancy/auxin associated protein PB1 PF00564.19 KFP02678.1 - 3.3e-12 45.9 0.2 7.3e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 PB1 domain PDZ PF00595.19 KFP02678.1 - 7.2e-12 45.3 0.3 1.6e-11 44.1 0.2 1.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP02678.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Enkurin PF13864.1 KFP02679.1 - 4.1e-27 94.2 2.6 4.1e-27 94.2 1.8 2.8 3 0 0 3 3 3 1 Calmodulin-binding GFO_IDH_MocA PF01408.17 KFP02680.1 - 8.1e-15 55.4 0.0 3.1e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KFP02680.1 - 0.00079 19.8 0.0 0.0027 18.0 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KFP02680.1 - 0.0027 17.8 0.0 0.0094 16.0 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA_C PF02894.12 KFP02680.1 - 0.033 13.9 0.1 0.071 12.9 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain XdhC_C PF13478.1 KFP02680.1 - 0.062 13.6 0.0 6.7 7.0 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain CIAPIN1 PF05093.8 KFP02681.1 - 1.4e-25 89.3 15.0 1.8e-22 79.3 10.4 2.5 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_31 PF13847.1 KFP02681.1 - 5.8e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP02681.1 - 8e-05 23.0 0.0 0.00019 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP02681.1 - 0.044 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFP02681.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFP02681.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain COQ9 PF08511.6 KFP02682.1 - 2.7e-34 116.4 0.2 5e-34 115.6 0.2 1.4 1 0 0 1 1 1 1 COQ9 RNA_pol_A_bac PF01000.21 KFP02683.1 - 2.1e-40 137.3 0.0 3e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFP02683.1 - 3.7e-10 38.7 0.0 4.6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain IRS PF02174.12 KFP02684.1 - 6.7e-29 99.4 0.0 1.1e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 PTB domain (IRS-1 type) PH PF00169.24 KFP02684.1 - 1.5e-06 28.3 0.3 3e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP02684.1 - 0.00083 19.5 2.2 0.0078 16.4 1.4 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain Furin-like PF00757.15 KFP02684.1 - 0.033 13.8 1.7 0.066 12.8 1.2 1.4 1 0 0 1 1 1 0 Furin-like cysteine rich region RGM_C PF06534.8 KFP02684.1 - 0.047 12.8 0.2 0.099 11.8 0.1 1.4 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Myosin_tail_1 PF01576.14 KFP02685.1 - 1.6e-06 26.1 73.2 8.1e-05 20.5 32.9 3.3 2 1 1 3 3 3 3 Myosin tail Filament PF00038.16 KFP02685.1 - 0.0058 16.1 63.3 0.017 14.6 0.4 3.6 1 1 0 2 2 2 2 Intermediate filament protein Fib_alpha PF08702.5 KFP02685.1 - 0.0071 16.4 37.8 0.098 12.7 3.5 4.4 2 1 2 4 4 4 3 Fibrinogen alpha/beta chain family DUF2163 PF09931.4 KFP02685.1 - 0.03 14.0 1.1 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2163) Ycf54 PF10674.4 KFP02685.1 - 0.04 14.0 3.8 0.087 12.9 0.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2488) Reo_sigmaC PF04582.7 KFP02685.1 - 0.13 11.3 5.3 1.8 7.6 1.0 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KFP02685.1 - 0.15 12.2 21.8 0.093 12.9 0.8 5.5 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 KFP02685.1 - 2.5 7.3 62.3 0.27 10.5 12.7 3.7 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF972 PF06156.8 KFP02685.1 - 3.1 8.1 50.7 0.52 10.6 4.1 5.5 2 1 3 5 5 5 0 Protein of unknown function (DUF972) FlxA PF14282.1 KFP02685.1 - 5.2 7.0 0.0 5.2 7.0 0.0 5.2 3 1 3 6 6 6 0 FlxA-like protein ATG16 PF08614.6 KFP02685.1 - 7.8 6.2 69.6 2.7 7.7 1.2 4.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.3 KFP02685.1 - 8.6 5.5 47.5 0.017 14.3 5.2 5.0 2 1 3 5 5 5 0 Protein of unknown function (DUF3450) 7tm_2 PF00002.19 KFP02686.1 - 3.3e-32 111.5 19.0 4.5e-32 111.0 13.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFP02686.1 - 4.1e-12 45.9 6.1 1e-11 44.6 4.2 1.8 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Zona_pellucida PF00100.18 KFP02687.1 - 3.4e-50 170.9 0.5 4.2e-50 170.6 0.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.22 KFP02687.1 - 7.8e-08 32.1 8.7 2.3e-07 30.6 6.0 1.9 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFP02687.1 - 0.0017 18.3 2.5 0.0017 18.3 1.8 2.5 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_2 PF07974.8 KFP02687.1 - 0.0062 16.6 8.9 0.019 15.1 6.2 1.8 1 0 0 1 1 1 1 EGF-like domain cEGF PF12662.2 KFP02687.1 - 0.028 14.0 1.2 0.028 14.0 0.8 1.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like Fusion_gly PF00523.13 KFP02687.1 - 0.067 11.2 0.1 0.17 9.9 0.0 1.6 2 0 0 2 2 2 0 Fusion glycoprotein F0 EGF_3 PF12947.2 KFP02687.1 - 0.13 12.2 3.7 0.34 10.9 2.5 1.7 1 0 0 1 1 1 0 EGF domain WD40 PF00400.27 KFP02690.1 - 6.8e-60 196.9 11.5 1.7e-13 49.8 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Katanin_con80 PF13925.1 KFP02690.1 - 2.5e-50 170.4 3.5 8.3e-50 168.7 2.4 1.9 1 1 0 1 1 1 1 con80 domain of Katanin Nucleoporin_N PF08801.6 KFP02690.1 - 1.9e-06 26.9 0.0 9e-05 21.3 0.0 2.7 1 1 1 2 2 2 1 Nup133 N terminal like eIF2A PF08662.6 KFP02690.1 - 2.3e-06 27.4 0.0 0.00035 20.3 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFP02690.1 - 0.031 12.4 0.8 8.3 4.4 0.0 3.5 1 1 3 4 4 4 0 Nucleoporin Nup120/160 cNMP_binding PF00027.24 KFP02691.1 - 2.6e-15 55.9 0.0 4.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-H2C2_2 PF13465.1 KFP02692.1 - 8.2e-61 199.4 142.8 4.4e-10 39.3 0.9 17.6 18 0 0 18 18 18 15 Zinc-finger double domain zf-C2H2 PF00096.21 KFP02692.1 - 7.7e-55 180.0 156.6 3.8e-06 26.9 0.7 17.2 17 0 0 17 17 17 15 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP02692.1 - 1.8e-38 128.0 133.9 0.00013 22.0 2.9 16.9 17 0 0 17 17 17 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP02692.1 - 2.2e-21 75.4 87.7 0.0034 17.4 0.2 14.9 15 0 0 15 15 15 11 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP02692.1 - 1.3e-16 59.8 106.1 0.008 16.0 0.6 16.3 16 0 0 16 16 16 10 C2H2-type zinc finger zf-met PF12874.2 KFP02692.1 - 1.9e-16 59.6 101.9 0.014 15.5 0.5 14.9 15 0 0 15 15 15 9 Zinc-finger of C2H2 type BolA PF01722.13 KFP02692.1 - 0.0002 21.2 26.8 0.7 9.8 0.1 8.0 4 3 3 8 8 8 2 BolA-like protein C1_1 PF00130.17 KFP02692.1 - 0.14 11.8 86.7 0.086 12.5 0.9 11.0 3 2 8 12 12 12 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Antimicrobial_3 PF08025.6 KFP02692.1 - 0.15 11.8 1.0 32 4.3 0.0 4.0 3 0 0 3 3 3 0 Spider antimicrobial peptide HVSL PF09749.4 KFP02693.1 - 1.1e-60 204.6 0.0 1.3e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Peptidase_M10 PF00413.19 KFP02694.1 - 1.6e-56 190.3 0.0 2.3e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFP02694.1 - 2.9e-41 138.9 18.6 1.5e-15 56.6 0.8 4.6 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFP02694.1 - 4.8e-10 39.2 0.1 9.4e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFP02694.1 - 0.0097 15.3 0.3 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFP02694.1 - 0.017 15.6 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFP02694.1 - 0.039 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.3 KFP02694.1 - 0.071 11.5 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M54 PF07998.6 KFP02694.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_2 PF13574.1 KFP02694.1 - 0.11 12.5 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF667 PF05018.8 KFP02695.1 - 1.4e-84 282.0 0.7 1.6e-84 281.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) DUF667 PF05018.8 KFP02696.1 - 6.6e-86 286.4 0.6 7.4e-86 286.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.20 KFP02698.1 - 3.2e-65 219.8 0.8 3.9e-65 219.5 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02698.1 - 2.6e-21 75.8 0.2 5.3e-21 74.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFP02698.1 - 6.8e-10 39.0 0.0 3.6e-06 26.8 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP02698.1 - 0.0024 17.5 0.2 0.0056 16.2 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KFP02698.1 - 0.017 14.1 0.4 0.031 13.3 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_3 PF08447.6 KFP02698.1 - 0.03 14.4 0.1 0.094 12.8 0.1 1.8 1 0 0 1 1 1 0 PAS fold YrbL-PhoP_reg PF10707.4 KFP02698.1 - 0.063 12.5 1.2 0.76 9.0 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF4201 PF13870.1 KFP02699.1 - 1.7e-32 112.3 22.2 1.7e-32 112.3 15.4 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Ric8 PF10165.4 KFP02699.1 - 0.021 13.6 13.8 0.029 13.2 9.5 1.3 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Reo_sigmaC PF04582.7 KFP02699.1 - 0.07 12.2 7.7 1.4 8.0 0.1 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein COG2 PF06148.6 KFP02699.1 - 0.099 12.5 0.4 0.099 12.5 0.3 3.6 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.6 KFP02699.1 - 3.2 7.6 9.4 0.79 9.6 0.3 2.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 KFP02699.1 - 3.4 7.4 15.4 3.2 7.4 0.4 3.0 2 1 1 3 3 3 0 Laminin Domain II Z1 PF10593.4 KFP02699.1 - 3.7 6.7 10.0 5.8 6.0 0.2 2.4 2 1 0 2 2 2 0 Z1 domain Sld5 PF05916.6 KFP02700.1 - 5.1e-08 33.1 0.0 6.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Trans_reg_C PF00486.23 KFP02700.1 - 0.045 13.6 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal I-set PF07679.11 KFP02701.1 - 3.3e-42 142.2 0.0 1.6e-12 47.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP02701.1 - 2e-29 101.4 0.1 3.3e-11 43.1 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP02701.1 - 2.3e-19 69.6 0.6 6.8e-08 32.9 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP02701.1 - 1.2e-14 54.1 0.0 2.1e-05 24.5 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP02701.1 - 1.6e-09 37.6 0.3 0.00062 19.6 0.1 4.5 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP02701.1 - 3.3e-09 36.5 0.3 0.069 13.0 0.1 4.1 3 1 0 3 3 3 3 CD80-like C2-set immunoglobulin domain TSP_1 PF00090.14 KFP02701.1 - 5.1e-07 29.7 44.2 2.6e-06 27.4 6.8 4.8 4 1 0 4 4 4 3 Thrombospondin type 1 domain TSP_1 PF00090.14 KFP02702.1 - 7.6e-24 83.5 71.1 7.1e-06 26.0 2.3 7.7 6 2 0 6 6 6 6 Thrombospondin type 1 domain ADAM_spacer1 PF05986.9 KFP02702.1 - 0.006 16.4 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 BAR PF03114.13 KFP02704.1 - 1.8e-71 240.2 7.0 2.1e-71 240.0 4.8 1.0 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFP02704.1 - 3.3e-15 55.1 0.2 1.4e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFP02704.1 - 8.5e-15 54.0 0.1 1.6e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP02704.1 - 1.9e-13 49.7 0.0 4e-13 48.6 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain BAR_2 PF10455.4 KFP02704.1 - 3.4e-08 32.7 4.1 1.2e-07 30.9 1.8 1.9 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Exonuc_VII_L PF02601.10 KFP02704.1 - 0.14 11.3 3.2 0.19 10.8 2.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4600 PF15372.1 KFP02704.1 - 9.4 6.4 12.2 1.7 8.8 5.4 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) PGA_cap PF09587.5 KFP02705.1 - 0.045 13.1 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Fib_alpha PF08702.5 KFP02705.1 - 0.49 10.5 25.1 0.17 12.0 7.2 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 KFP02705.1 - 1.2 8.2 14.0 1.2 8.2 3.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ING PF12998.2 KFP02705.1 - 2.4 8.4 26.9 0.32 11.3 7.4 3.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF641 PF04859.7 KFP02705.1 - 5.5 6.7 20.9 0.075 12.7 2.4 3.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) COG2 PF06148.6 KFP02705.1 - 9.6 6.0 20.9 0.52 10.1 3.2 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C2H2_4 PF13894.1 KFP02706.1 - 4.1e-12 45.5 29.6 0.009 16.2 0.7 6.8 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP02706.1 - 3.7e-09 36.3 33.1 0.0033 17.6 1.0 6.9 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.2 KFP02706.1 - 1.4e-07 31.4 21.1 0.0063 16.6 0.1 5.9 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP02706.1 - 0.0093 16.0 20.9 0.63 10.2 0.4 4.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding Arg_repressor PF01316.16 KFP02706.1 - 0.058 12.9 0.0 0.24 10.9 0.0 2.0 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain LEDGF PF11467.3 KFP02708.1 - 1.9e-39 133.5 6.1 1.9e-39 133.5 4.2 2.3 3 0 0 3 3 3 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.12 KFP02708.1 - 5.9e-12 45.6 0.1 5.9e-12 45.6 0.1 3.7 4 1 0 4 4 4 1 PWWP domain zf-SNAP50_C PF12251.3 KFP02709.1 - 2.7e-70 235.7 3.2 3.4e-70 235.4 2.2 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF3808 PF10300.4 KFP02710.1 - 4.1e-165 549.8 10.0 5e-165 549.5 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 KFP02710.1 - 1.1e-11 44.4 5.5 1.1e-07 31.7 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFP02710.1 - 4.4e-07 29.4 8.1 0.001 18.6 0.1 4.6 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 KFP02710.1 - 1.8e-06 27.4 11.2 0.32 11.0 0.2 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFP02710.1 - 3.1e-06 26.5 5.2 0.11 12.1 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP02710.1 - 0.0022 18.3 13.8 0.48 11.0 0.2 6.9 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP02710.1 - 0.0074 16.0 2.1 2.7 8.0 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat B1 PF02246.10 KFP02710.1 - 0.038 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein L b1 domain TPR_19 PF14559.1 KFP02710.1 - 0.11 12.9 8.3 0.62 10.4 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFP02710.1 - 0.18 12.5 2.4 45 4.8 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP02710.1 - 0.2 11.5 9.5 9.8 6.2 0.4 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DAN PF03045.10 KFP02711.1 - 6.6e-35 119.1 10.3 6.9e-35 119.1 6.5 1.5 2 0 0 2 2 2 1 DAN domain Cys_knot PF00007.17 KFP02711.1 - 0.00013 22.0 7.4 0.0002 21.3 5.1 1.3 1 0 0 1 1 1 1 Cystine-knot domain Sclerostin PF05463.6 KFP02711.1 - 0.00017 21.1 2.8 0.00054 19.5 2.0 1.8 1 1 0 1 1 1 1 Sclerostin (SOST) DUF1661 PF07877.6 KFP02711.1 - 0.17 11.4 0.2 0.17 11.4 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1661) zf-DHHC PF01529.15 KFP02712.1 - 2.2e-32 111.8 10.8 2.2e-32 111.8 7.5 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KFP02712.1 - 0.054 13.3 1.4 0.099 12.4 1.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily CTF_NFI PF00859.13 KFP02713.1 - 1.1e-116 389.6 30.6 1.6e-116 389.2 21.2 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region LURAP PF14854.1 KFP02714.1 - 9.6e-14 51.1 0.6 1.3e-13 50.7 0.4 1.2 1 0 0 1 1 1 1 Leucine rich adaptor protein LURAP PF14854.1 KFP02715.1 - 3e-40 136.6 2.6 3.7e-40 136.3 1.8 1.1 1 0 0 1 1 1 1 Leucine rich adaptor protein Tyrosinase PF00264.15 KFP02716.1 - 1.7e-33 116.6 0.1 2.3e-33 116.2 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.19 KFP02716.1 - 0.45 10.4 13.3 1.6 8.7 6.7 3.0 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 KFP02716.1 - 1.2 9.3 14.5 0.1 12.7 3.1 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF GDC-P PF02347.11 KFP02717.1 - 2.9e-176 586.3 0.0 5.3e-163 542.6 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KFP02717.1 - 6.4e-09 35.3 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFP02717.1 - 1.1e-05 24.3 0.0 8.6e-05 21.4 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Pyridoxal_deC PF00282.14 KFP02717.1 - 0.0041 15.6 0.2 0.093 11.1 0.0 2.2 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 KFP02717.1 - 0.014 14.3 0.0 0.042 12.7 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II SAD_SRA PF02182.12 KFP02718.1 - 2.3e-53 179.6 0.0 5.2e-53 178.5 0.0 1.6 1 0 0 1 1 1 1 SAD/SRA domain DUF3590 PF12148.3 KFP02718.1 - 5.4e-38 128.4 1.4 1.7e-33 114.0 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3590) PHD PF00628.24 KFP02718.1 - 7.4e-10 38.3 10.7 7.4e-10 38.3 7.4 3.5 2 2 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.1 KFP02718.1 - 7.6e-05 22.6 13.3 7.6e-05 22.6 9.2 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP02718.1 - 0.00028 20.4 13.4 0.00028 20.4 9.3 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP02718.1 - 0.00046 19.8 10.6 0.00046 19.8 7.3 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP02718.1 - 0.0012 18.5 12.7 0.0012 18.5 8.8 3.5 2 1 0 2 2 2 1 zinc-RING finger domain PHD_2 PF13831.1 KFP02718.1 - 0.0014 17.9 2.6 0.0014 17.9 1.8 3.5 3 0 0 3 3 3 1 PHD-finger ubiquitin PF00240.18 KFP02718.1 - 0.12 11.7 1.7 0.23 10.8 0.0 2.4 3 0 0 3 3 3 0 Ubiquitin family Peptidase_C62 PF12380.3 KFP02719.1 - 0.026 13.3 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase MOZ_SAS PF01853.13 KFP02719.1 - 0.029 13.6 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 MOZ/SAS family FYVE_2 PF02318.11 KFP02720.1 - 0.05 13.4 2.9 0.24 11.3 2.0 2.2 1 0 0 1 1 1 0 FYVE-type zinc finger MLANA PF14991.1 KFP02722.1 - 1e-35 122.3 0.0 1.1e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Protein melan-A WBP-1 PF11669.3 KFP02722.1 - 0.0068 16.4 0.0 0.0094 16.0 0.0 1.2 1 0 0 1 1 1 1 WW domain-binding protein 1 SKG6 PF08693.5 KFP02722.1 - 1.2 8.4 3.3 2.4 7.5 2.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M28 PF04389.12 KFP02723.1 - 1.7e-38 132.1 0.0 2.8e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFP02723.1 - 3.9e-08 33.0 0.0 6.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KFP02723.1 - 0.046 12.4 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase SGL PF08450.7 KFP02723.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Ig_2 PF13895.1 KFP02724.1 - 1.6e-10 40.9 0.5 0.0001 22.3 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP02724.1 - 7.2e-09 35.5 0.5 4.3e-07 29.8 0.0 2.1 1 1 1 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 KFP02724.1 - 3.8e-08 33.0 0.1 0.0068 16.2 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP02724.1 - 5.9e-05 23.4 1.2 0.017 15.5 0.1 3.1 2 1 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.10 KFP02724.1 - 0.00029 20.7 0.5 0.00085 19.2 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain C2-set_2 PF08205.7 KFP02724.1 - 0.00053 19.8 0.1 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFP02724.1 - 0.013 15.5 0.6 0.33 11.1 0.0 2.9 2 2 0 2 2 2 0 Immunoglobulin domain V-set PF07686.12 KFP02725.1 - 1.2e-12 47.7 0.1 3.1e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP02725.1 - 7.2e-11 42.0 0.3 7e-05 22.8 0.0 2.3 1 1 1 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP02725.1 - 2e-10 40.9 0.4 0.00093 19.6 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP02725.1 - 1.6e-09 37.4 0.2 7.6e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFP02725.1 - 7.8e-05 22.7 0.5 0.011 15.8 0.0 3.5 3 1 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.10 KFP02725.1 - 0.0098 15.8 1.3 0.023 14.7 0.3 2.0 2 0 0 2 2 2 1 Immunoglobulin C1-set domain DUF2368 PF10166.4 KFP02726.1 - 3e-35 120.7 0.1 3.2e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Hepcidin PF06446.7 KFP02727.1 - 0.0087 16.4 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 Hepcidin Insulin PF00049.13 KFP02727.1 - 0.0087 16.8 0.0 0.01 16.5 0.0 1.2 1 0 0 1 1 1 1 Insulin/IGF/Relaxin family Ins_beta PF03488.9 KFP02727.1 - 0.043 13.6 0.8 0.062 13.0 0.6 1.2 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type HIF-1 PF11413.3 KFP02727.1 - 0.1 11.7 0.2 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Pkinase_Tyr PF07714.12 KFP02728.1 - 1.1e-147 490.0 0.0 1.9e-87 292.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFP02728.1 - 1.1e-75 254.1 0.0 3e-50 170.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KFP02728.1 - 4.7e-06 25.7 0.0 0.00036 19.5 0.0 2.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP02728.1 - 6.9e-05 21.9 0.3 0.079 12.0 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP02728.1 - 0.00082 18.7 1.1 0.19 11.0 0.1 2.5 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 KFP02728.1 - 0.059 13.0 0.0 2.8 7.5 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RTC PF01137.16 KFP02730.1 - 1.2e-57 194.2 0.0 1.7e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KFP02730.1 - 1.2e-32 111.9 0.0 1.8e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SDF PF00375.13 KFP02731.1 - 3.1e-135 450.9 25.5 3.5e-135 450.7 17.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Sad1_UNC PF07738.8 KFP02733.1 - 4.5e-33 113.8 0.0 5e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ADK PF00406.17 KFP02734.1 - 1.6e-51 174.1 0.0 1.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFP02734.1 - 1.6e-16 59.6 0.0 3.1e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KFP02734.1 - 1.7e-12 48.2 0.0 4.1e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFP02734.1 - 1.5e-05 24.9 0.1 7.1e-05 22.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFP02734.1 - 0.00025 21.3 0.0 0.00063 20.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFP02734.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Matrilin_ccoil PF10393.4 KFP02734.1 - 0.037 13.3 0.2 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin RNA_helicase PF00910.17 KFP02734.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CDC37_M PF08565.6 KFP02735.1 - 1.5e-40 138.5 2.6 1.8e-40 138.2 1.4 1.4 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain Ribosomal_S8e PF01201.17 KFP02737.1 - 9.4e-33 113.1 0.0 1.6e-32 112.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e GTP_EFTU PF00009.22 KFP02738.1 - 6.1e-64 214.9 0.0 9.6e-64 214.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KFP02738.1 - 7.8e-28 96.1 0.0 4e-27 93.8 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 KFP02738.1 - 2.3e-24 85.0 0.1 5.1e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 KFP02738.1 - 6.5e-12 45.0 0.0 2e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 KFP02738.1 - 1.5e-08 34.6 0.0 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFP02738.1 - 0.00033 20.5 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFP02738.1 - 0.0056 17.1 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KFP02738.1 - 0.013 14.8 0.0 0.075 12.3 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.11 KFP02738.1 - 0.055 12.5 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Glyco_hydro_20 PF00728.17 KFP02739.1 - 2.2e-83 280.3 0.0 2.8e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KFP02739.1 - 1.7e-06 28.7 0.0 3.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Kelch_1 PF01344.20 KFP02741.1 - 1.2e-49 165.6 3.5 1.5e-11 43.6 0.0 5.5 5 0 0 5 5 5 5 Kelch motif BACK PF07707.10 KFP02741.1 - 5.1e-30 103.3 1.8 1.6e-29 101.7 0.9 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFP02741.1 - 3.3e-29 101.1 0.2 6.5e-29 100.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 KFP02741.1 - 4.1e-29 99.5 4.3 4.5e-05 23.4 0.2 6.1 2 2 4 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFP02741.1 - 3e-23 81.3 1.2 3.6e-08 33.0 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KFP02741.1 - 9.4e-23 79.7 0.6 3.8e-06 26.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP02741.1 - 3e-21 74.2 2.6 0.00014 21.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KFP02741.1 - 7.3e-18 64.1 1.2 8.5e-09 35.1 0.0 5.7 6 0 0 6 6 6 4 Kelch motif DUF3342 PF11822.3 KFP02741.1 - 3e-05 23.3 0.1 9e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) PFU PF09070.6 KFP02741.1 - 0.13 12.2 0.1 0.66 9.9 0.0 2.2 3 0 0 3 3 3 0 PFU (PLAA family ubiquitin binding) UTP15_C PF09384.5 KFP02742.1 - 3e-48 163.2 0.1 4.8e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KFP02742.1 - 1.1e-25 88.4 9.2 1.1e-07 31.4 0.1 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFP02742.1 - 1.2e-05 25.0 0.0 0.016 14.9 0.0 3.2 2 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Ank PF00023.25 KFP02743.1 - 1.1e-29 100.6 0.1 5e-10 38.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KFP02743.1 - 6.8e-28 96.8 0.2 6.8e-15 55.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP02743.1 - 6.5e-26 90.2 0.3 4.7e-08 33.3 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP02743.1 - 3.5e-24 84.2 1.4 4.9e-10 39.3 0.2 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02743.1 - 1.3e-21 74.5 0.0 3.4e-07 29.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat NAC PF01849.13 KFP02744.1 - 2.2e-24 84.7 0.3 3.1e-24 84.2 0.2 1.3 1 0 0 1 1 1 1 NAC domain LolA PF03548.10 KFP02744.1 - 0.045 13.3 0.7 0.057 13.0 0.5 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA RE_HaeII PF09554.5 KFP02744.1 - 0.046 12.7 0.1 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 HaeII restriction endonuclease DUF4526 PF15029.1 KFP02745.1 - 3.6e-110 367.0 0.1 4e-110 366.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4526) PIRT PF15099.1 KFP02745.1 - 0.0027 16.9 0.1 0.0045 16.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family TMEM171 PF15471.1 KFP02745.1 - 0.036 12.8 4.7 0.026 13.3 2.0 1.6 1 1 0 1 1 1 0 Transmembrane protein family 171 DUF2371 PF10177.4 KFP02745.1 - 0.81 9.5 5.2 1.5 8.7 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) Tetraspannin PF00335.15 KFP02745.1 - 8.4 5.5 9.3 5.4 6.2 0.2 2.2 2 0 0 2 2 2 0 Tetraspanin family TMEM171 PF15471.1 KFP02746.1 - 1.4e-154 513.6 1.4 1.7e-154 513.3 1.0 1.0 1 0 0 1 1 1 1 Transmembrane protein family 171 EVC2_like PF12297.3 KFP02746.1 - 0.18 10.4 0.0 0.18 10.4 0.0 1.8 3 0 0 3 3 3 0 Ellis van Creveld protein 2 like protein PRA1 PF03208.14 KFP02746.1 - 3.6 6.9 8.3 0.16 11.2 0.4 2.4 2 1 1 3 3 3 0 PRA1 family protein DUF2371 PF10177.4 KFP02746.1 - 6.3 6.6 8.7 0.27 11.1 1.0 2.4 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Sec61_beta PF03911.11 KFP02747.1 - 1e-21 76.4 0.0 1.3e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family zf-C4 PF00105.13 KFP02748.1 - 3.1e-31 107.4 18.2 5.5e-31 106.6 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFP02748.1 - 4.3e-17 61.9 0.0 8.2e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor C9orf72-like PF15019.1 KFP02748.1 - 0.024 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family SNARE PF05739.14 KFP02749.1 - 3.8e-11 42.4 1.6 4.7e-11 42.2 0.1 1.8 2 0 0 2 2 2 1 SNARE domain Gly-zipper_OmpA PF13436.1 KFP02749.1 - 0.0065 16.1 2.4 0.011 15.3 1.7 1.3 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Vac_Fusion PF02346.11 KFP02749.1 - 0.018 14.4 0.7 0.046 13.1 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein RseC_MucC PF04246.7 KFP02749.1 - 0.028 13.9 0.2 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC TraT PF05818.7 KFP02749.1 - 0.033 13.6 1.6 0.052 12.9 1.1 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein SlyX PF04102.7 KFP02749.1 - 0.07 13.5 1.8 0.21 12.0 0.2 2.4 2 0 0 2 2 2 0 SlyX Gly-zipper_Omp PF13488.1 KFP02749.1 - 0.12 12.0 12.8 0.22 11.1 8.9 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KFP02749.1 - 0.83 9.2 15.4 1.4 8.5 10.7 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper GrpE PF01025.14 KFP02749.1 - 6.4 6.2 7.2 1 8.8 0.4 2.2 1 1 0 2 2 2 0 GrpE Rick_17kDa_Anti PF05433.10 KFP02749.1 - 7.1 6.3 19.8 10 5.8 13.7 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain Thioredoxin_6 PF13848.1 KFP02750.1 - 6.5e-45 153.1 0.3 7e-40 136.7 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 KFP02750.1 - 1.7e-21 75.8 0.0 4e-21 74.6 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.12 KFP02750.1 - 7.1e-09 34.9 0.1 1.9e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 KFP02750.1 - 9.2e-05 22.6 0.0 0.00039 20.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFP02750.1 - 0.00089 19.3 0.7 0.0054 16.8 0.1 2.4 2 1 0 2 2 2 1 Thioredoxin-like HyaE PF07449.6 KFP02750.1 - 0.0012 18.7 0.0 0.0038 17.0 0.0 1.8 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 KFP02750.1 - 0.0093 15.9 0.1 0.16 12.0 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like Ank_2 PF12796.2 KFP02751.1 - 5.6e-98 321.4 16.6 5.2e-22 77.9 0.3 8.9 2 1 5 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFP02751.1 - 1.2e-93 302.5 26.5 1.5e-08 33.9 0.0 16.0 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.1 KFP02751.1 - 1.4e-77 254.8 19.6 2.9e-12 46.7 0.1 11.2 6 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP02751.1 - 5.7e-69 226.6 25.9 3.9e-11 42.8 0.1 12.6 4 4 9 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02751.1 - 6.5e-69 220.9 20.2 0.00018 21.4 0.0 16.4 16 0 0 16 16 16 13 Ankyrin repeat IQ PF00612.22 KFP02751.1 - 1.3e-06 27.4 12.7 0.0026 17.2 0.8 3.4 3 0 0 3 3 3 2 IQ calmodulin-binding motif Antimicrobial_6 PF08036.6 KFP02751.1 - 0.04 13.6 2.5 0.2 11.4 0.9 2.3 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide Ipi1_N PF12333.3 KFP02752.1 - 1.2e-19 70.1 6.2 3.1e-19 68.8 0.4 3.8 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 KFP02752.1 - 0.00042 20.2 2.2 0.00064 19.6 0.2 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFP02752.1 - 0.006 17.0 0.0 0.14 12.6 0.0 3.5 2 1 0 2 2 2 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFP02752.1 - 0.013 15.8 0.1 0.11 12.8 0.0 2.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KFP02752.1 - 0.071 13.3 0.5 0.58 10.4 0.0 2.9 3 0 0 3 3 3 0 HEAT repeats DUF2474 PF10617.4 KFP02752.1 - 0.9 9.1 4.1 16 5.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) Myb_DNA-bind_5 PF13873.1 KFP02753.1 - 7.6e-22 77.0 2.0 7.6e-22 77.0 1.4 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KFP02753.1 - 0.022 14.9 1.9 0.022 14.9 1.3 2.8 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Macro PF01661.16 KFP02753.1 - 0.029 14.2 0.5 0.12 12.3 0.0 2.1 2 2 0 2 2 2 0 Macro domain DUSP PF06337.7 KFP02753.1 - 0.28 11.5 2.0 3.3 8.1 0.0 3.2 2 2 0 2 2 2 0 DUSP domain Myb_DNA-bind_3 PF12776.2 KFP02753.1 - 2.1 9.0 10.0 11 6.7 0.6 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain EF-hand_1 PF00036.27 KFP02754.1 - 1.4e-26 89.7 4.5 1.9e-07 29.8 0.1 5.2 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 KFP02754.1 - 1.3e-22 79.7 4.4 9.6e-12 44.8 0.7 3.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KFP02754.1 - 4.7e-22 75.8 3.0 1.2e-06 27.8 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.1 KFP02754.1 - 7.2e-21 73.5 5.5 2.4e-06 27.0 0.1 5.0 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 KFP02754.1 - 1e-10 40.4 10.5 0.00057 19.1 0.0 4.1 5 0 0 5 5 5 3 EF hand EF-hand_9 PF14658.1 KFP02754.1 - 0.043 13.7 0.1 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 KFP02754.1 - 0.055 13.1 0.2 2.5 7.8 0.0 3.1 4 0 0 4 4 4 0 EF hand DHC_N1 PF08385.7 KFP02755.1 - 6.4e-45 153.5 5.1 7e-45 153.4 3.5 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 FerA PF08165.6 KFP02755.1 - 0.065 12.9 2.9 7.9 6.2 0.0 3.2 2 1 0 2 2 2 0 FerA (NUC095) domain PTRF_SDPR PF15237.1 KFP02756.1 - 7.7e-86 287.4 19.6 1e-85 287.1 13.6 1.1 1 0 0 1 1 1 1 PTRF/SDPR family Prominin PF05478.6 KFP02756.1 - 0.0012 16.4 8.6 0.0023 15.5 5.9 1.4 1 1 0 1 1 1 1 Prominin Vac_Fusion PF02346.11 KFP02756.1 - 0.028 13.8 1.6 1.1 8.6 0.1 2.8 2 0 0 2 2 2 0 Chordopoxvirus fusion protein PilJ PF13675.1 KFP02756.1 - 0.056 13.7 2.5 6.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin_2 PF14523.1 KFP02756.1 - 0.2 11.7 17.5 0.044 13.8 1.5 3.0 2 1 2 4 4 4 0 Syntaxin-like protein MCPsignal PF00015.16 KFP02756.1 - 0.37 10.2 14.3 0.23 11.0 7.2 2.4 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 KFP02756.1 - 1.2 8.9 12.0 0.53 10.0 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 KFP02756.1 - 1.6 9.1 12.9 4.4 7.7 2.8 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF948 PF06103.6 KFP02756.1 - 2.6 7.9 5.9 9.1 6.2 1.8 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DASH_Dad4 PF08650.5 KFP02756.1 - 5.1 7.0 8.0 5.4 6.9 0.7 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad4 Kazal_2 PF07648.10 KFP02757.1 - 1.2e-18 66.6 15.1 1.9e-11 43.7 2.8 3.6 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP02757.1 - 4e-15 55.5 32.3 3.4e-08 33.3 10.0 3.7 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain hEGF PF12661.2 KFP02757.1 - 0.002 18.0 3.3 0.002 18.0 2.3 3.1 3 0 0 3 3 3 1 Human growth factor-like EGF EphA2_TM PF14575.1 KFP02757.1 - 0.043 14.1 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 KFP02757.1 - 0.063 12.9 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Protocadherin Zip PF02535.17 KFP02758.1 - 3e-09 36.3 14.7 4.4e-09 35.7 10.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Bap31 PF05529.7 KFP02758.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Med19 PF10278.4 KFP02758.1 - 0.93 9.1 9.3 1.1 8.9 3.7 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 GCV_H PF01597.14 KFP02759.1 - 4.6e-08 32.7 0.0 8.7e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Glycine cleavage H-protein SapB_1 PF05184.10 KFP02759.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Saposin-like type B, region 1 Vinculin PF01044.14 KFP02760.1 - 9.2e-53 179.5 19.7 6.3e-33 113.8 3.8 3.3 3 1 0 3 3 3 3 Vinculin family WXG100 PF06013.7 KFP02760.1 - 0.16 11.9 6.1 0.049 13.6 0.7 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG COG5 PF10392.4 KFP02760.1 - 0.21 11.5 10.3 0.069 13.1 2.2 3.7 3 2 1 4 4 4 0 Golgi transport complex subunit 5 WD40 PF00400.27 KFP02761.1 - 3.7e-56 185.1 27.5 2.8e-07 30.1 0.0 12.8 13 0 0 13 13 13 10 WD domain, G-beta repeat eIF2A PF08662.6 KFP02761.1 - 0.019 14.6 5.4 0.93 9.1 0.1 3.7 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KFP02761.1 - 0.028 14.0 1.3 86 2.9 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat 7tm_3 PF00003.17 KFP02762.1 - 7e-52 176.1 12.1 9e-52 175.7 8.4 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Cation_ATPase_C PF00689.16 KFP02762.1 - 0.0091 15.5 16.4 0.23 10.9 1.2 3.0 2 1 1 3 3 3 3 Cation transporting ATPase, C-terminus DUF869 PF05911.6 KFP02762.1 - 0.011 14.0 1.6 0.015 13.5 1.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) PgaD PF13994.1 KFP02762.1 - 0.026 13.9 1.2 0.079 12.4 0.0 2.3 2 0 0 2 2 2 0 PgaD-like protein APG6 PF04111.7 KFP02762.1 - 0.22 10.5 5.0 0.34 9.9 3.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP-synt_8 PF00895.15 KFP02762.1 - 4.9 7.4 5.9 4 7.7 0.2 2.9 2 0 0 2 2 2 0 ATP synthase protein 8 Kelch_6 PF13964.1 KFP02765.1 - 3.4e-41 137.7 7.2 2.5e-07 30.5 0.0 6.2 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFP02765.1 - 2.4e-39 132.8 6.4 1.1e-09 37.8 0.0 6.4 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KFP02765.1 - 3.6e-39 132.0 13.6 1.1e-08 34.4 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KFP02765.1 - 3.4e-33 113.0 11.0 8.7e-07 28.9 0.0 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP02765.1 - 1.6e-31 107.6 8.3 1e-05 25.3 0.0 6.4 6 1 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFP02765.1 - 5.1e-26 89.4 13.6 6.2e-06 25.7 0.1 6.8 5 2 1 6 6 6 6 Kelch motif RAG2 PF03089.9 KFP02765.1 - 0.055 12.1 0.0 0.62 8.7 0.0 2.3 2 0 0 2 2 2 0 Recombination activating protein 2 Na_Ca_ex PF01699.19 KFP02766.1 - 5.6e-21 74.6 22.3 7.6e-12 45.0 2.5 3.4 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KFP02766.1 - 2.9e-19 69.2 11.0 2.9e-19 69.2 7.6 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF307) CytochromB561_N PF09786.4 KFP02767.1 - 1.7e-160 535.3 2.4 8.2e-160 533.0 1.7 1.8 1 1 0 1 1 1 1 Cytochrome B561, N terminal Propep_M14 PF02244.11 KFP02768.1 - 4.3e-23 80.7 0.9 6.7e-23 80.1 0.6 1.3 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Peptidase_M14 PF00246.19 KFP02768.1 - 6.2e-06 26.0 0.0 9.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase CbiK PF06180.6 KFP02768.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Pneumo_M2 PF07380.6 KFP02768.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.5 1 1 0 1 1 1 0 Pneumovirus M2 protein GATA PF00320.22 KFP02769.1 - 7e-09 34.8 3.1 1.4e-08 33.9 2.1 1.5 1 0 0 1 1 1 1 GATA zinc finger LIM PF00412.17 KFP02769.1 - 0.002 18.1 1.0 0.0035 17.3 0.7 1.3 1 0 0 1 1 1 1 LIM domain zf-CHY PF05495.7 KFP02769.1 - 0.043 13.9 1.8 0.082 13.0 1.2 1.4 1 0 0 1 1 1 0 CHY zinc finger RRN7 PF11781.3 KFP02769.1 - 0.051 13.0 0.3 0.092 12.2 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 KFP02769.1 - 0.16 11.8 3.0 0.33 10.8 2.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF2387 PF09526.5 KFP02769.1 - 0.42 10.5 3.0 0.84 9.5 2.1 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF1178 PF06676.6 KFP02769.1 - 0.62 10.2 4.8 0.26 11.4 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) TORC_M PF12885.2 KFP02770.1 - 9.9e-32 109.7 12.7 7.7e-31 106.8 6.4 2.5 2 1 0 2 2 2 2 Transducer of regulated CREB activity middle domain PAH PF02671.16 KFP02771.1 - 1.7e-10 40.3 2.7 0.00012 21.6 0.0 3.3 3 0 0 3 3 3 2 Paired amphipathic helix repeat Myb_DNA-bind_6 PF13921.1 KFP02771.1 - 4.6e-05 23.4 0.2 0.0054 16.8 0.0 3.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Tubulin_3 PF14881.1 KFP02772.1 - 7e-24 84.2 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KFP02772.1 - 4.3e-09 36.5 0.0 6.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain DAP3 PF10236.4 KFP02773.1 - 1.1e-89 300.4 0.0 1.3e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Fmp27_SW PF10305.4 KFP02773.1 - 0.00079 19.8 0.2 0.002 18.5 0.0 1.8 2 0 0 2 2 1 1 RNA pol II promoter Fmp27 protein domain AAA_16 PF13191.1 KFP02773.1 - 0.0044 17.0 0.0 0.0078 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KFP02773.1 - 0.0095 15.6 0.0 0.02 14.5 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 KFP02773.1 - 0.0096 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KFP02773.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFP02773.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFP02773.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 KFP02773.1 - 0.082 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KFP02773.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MobB PF03205.9 KFP02773.1 - 0.099 12.3 0.1 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KFP02773.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein BAH PF01426.13 KFP02774.1 - 2.7e-19 69.0 0.2 1.1e-18 67.1 0.1 2.2 2 0 0 2 2 2 1 BAH domain Bromodomain PF00439.20 KFP02774.1 - 2.9e-16 59.1 0.0 8.6e-16 57.6 0.0 1.8 1 0 0 1 1 1 1 Bromodomain SET PF00856.23 KFP02774.1 - 1.3e-11 45.0 1.8 0.00016 22.0 0.0 3.9 2 1 1 3 3 3 2 SET domain PHD PF00628.24 KFP02774.1 - 1.7e-06 27.5 13.7 1.7e-06 27.5 9.5 2.4 2 0 0 2 2 2 1 PHD-finger RUN PF02759.14 KFP02775.1 - 3.4e-19 68.8 0.0 6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 RUN domain SH3_1 PF00018.23 KFP02775.1 - 1.9e-09 36.7 0.0 5.5e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFP02775.1 - 1.1e-08 34.3 0.0 4.3e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFP02775.1 - 1.1e-07 31.2 0.0 3e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain polyprenyl_synt PF00348.12 KFP02776.1 - 1.3e-62 210.9 0.0 1.6e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Zw10 PF06248.8 KFP02776.1 - 0.014 13.5 0.0 0.019 13.1 0.0 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Erythro_esteras PF05139.9 KFP02776.1 - 0.043 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Erythromycin esterase cNMP_binding PF00027.24 KFP02777.1 - 6e-21 74.0 0.0 1.1e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 KFP02777.1 - 3.4e-19 68.9 10.3 1.1e-18 67.2 7.1 1.8 1 1 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.5 KFP02777.1 - 1.7e-13 49.7 0.6 1.7e-13 49.7 0.4 2.2 2 0 0 2 2 2 1 Ion transport protein N-terminal Ion_trans_2 PF07885.11 KFP02777.1 - 3.7e-05 23.3 0.2 0.00012 21.7 0.1 2.0 2 0 0 2 2 2 1 Ion channel SCAMP PF04144.8 KFP02778.1 - 1.4e-72 243.3 15.7 1.6e-72 243.0 10.9 1.0 1 0 0 1 1 1 1 SCAMP family CD20 PF04103.10 KFP02779.1 - 3.3e-16 59.5 9.9 4.2e-16 59.2 6.8 1.1 1 0 0 1 1 1 1 CD20-like family UPF0139 PF03669.8 KFP02779.1 - 0.75 9.3 5.7 0.84 9.1 1.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Glyco_hydro_30 PF02055.11 KFP02780.1 - 9.1e-198 657.4 0.1 1e-197 657.2 0.0 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF229 PF02995.12 KFP02780.1 - 0.12 10.7 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_30 PF02055.11 KFP02781.1 - 8.8e-172 571.7 0.0 9.8e-172 571.5 0.0 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF229 PF02995.12 KFP02781.1 - 0.054 11.9 0.0 0.095 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_30 PF02055.11 KFP02782.1 - 2.7e-57 194.0 0.1 3e-57 193.9 0.1 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 UPF0270 PF06794.7 KFP02782.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Glyco_hydro_30 PF02055.11 KFP02783.1 - 6.4e-83 278.6 0.0 7.1e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 TSP_C PF05735.7 KFP02784.1 - 5.2e-77 257.9 1.8 7.3e-77 257.4 1.2 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 KFP02784.1 - 9.7e-62 204.1 132.3 1.3e-14 53.3 7.0 9.6 7 2 1 8 8 8 7 Thrombospondin type 3 repeat COMP PF11598.3 KFP02784.1 - 3.3e-22 78.2 3.7 5.7e-22 77.5 2.6 1.4 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein EGF_CA PF07645.10 KFP02784.1 - 1.1e-12 47.7 20.2 7.5e-08 32.2 0.9 5.7 5 0 0 5 5 5 2 Calcium-binding EGF domain cEGF PF12662.2 KFP02784.1 - 1.9e-07 30.5 30.8 7.4e-05 22.3 0.8 5.2 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF_3 PF12947.2 KFP02784.1 - 1.6e-05 24.7 8.0 1.6e-05 24.7 5.6 6.7 4 3 1 5 5 5 3 EGF domain Laminin_G_2 PF02210.19 KFP02784.1 - 0.0044 17.0 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain EGF PF00008.22 KFP02784.1 - 0.0091 15.9 6.6 0.0091 15.9 4.6 5.1 4 0 0 4 4 4 1 EGF-like domain EGF_MSP1_1 PF12946.2 KFP02784.1 - 0.44 10.3 20.9 0.065 13.0 4.5 3.2 2 0 0 2 2 2 0 MSP1 EGF domain 1 EphA2_TM PF14575.1 KFP02785.1 - 0.022 15.1 0.0 0.027 14.8 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KFP02785.1 - 0.032 12.4 0.0 0.033 12.4 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM52 PF14979.1 KFP02785.1 - 0.033 14.1 0.4 0.037 13.9 0.3 1.2 1 0 0 1 1 1 0 Transmembrane 52 LAT PF15234.1 KFP02785.1 - 0.084 12.3 0.2 0.085 12.3 0.1 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells Keratin_assoc PF09775.4 KFP02786.1 - 2.6e-46 156.4 0.3 2.9e-46 156.2 0.2 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 DUF1459 PF07312.6 KFP02786.1 - 0.084 12.8 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) MtN3_slv PF03083.11 KFP02787.1 - 1.9e-29 101.3 0.3 2.8e-29 100.8 0.2 1.2 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.9 KFP02787.1 - 0.0033 16.9 1.5 0.0052 16.3 0.1 2.1 2 0 0 2 2 2 1 PQ loop repeat DC_STAMP PF07782.8 KFP02788.1 - 3.2e-41 141.0 5.1 4.2e-41 140.6 3.6 1.2 1 0 0 1 1 1 1 DC-STAMP-like protein DC_STAMP PF07782.8 KFP02789.1 - 1.2e-51 175.0 0.0 3.1e-51 173.7 0.0 1.7 2 0 0 2 2 2 1 DC-STAMP-like protein DUF2393 PF09624.5 KFP02789.1 - 0.44 10.0 1.5 0.94 8.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) DUF1129 PF06570.6 KFP02789.1 - 4 6.6 5.7 54 2.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PAPS_reduct PF01507.14 KFP02790.1 - 6.5e-31 107.4 0.0 2.9e-28 98.8 0.0 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.19 KFP02790.1 - 1.3e-15 57.1 0.0 2.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PID PF00640.18 KFP02791.1 - 3e-31 108.2 0.0 4.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH2 PF00017.19 KFP02791.1 - 1.8e-18 66.1 0.0 2.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain DUF4581 PF15167.1 KFP02791.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) A_deamin PF02137.13 KFP02792.1 - 1.2e-104 350.2 0.1 1.8e-104 349.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain z-alpha PF02295.12 KFP02792.1 - 1.1e-38 130.8 0.2 3.2e-18 65.2 0.0 2.6 2 0 0 2 2 2 2 Adenosine deaminase z-alpha domain dsrm PF00035.20 KFP02792.1 - 1.7e-37 127.8 0.2 1.3e-12 48.1 0.0 3.9 3 0 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFP02792.1 - 4.1e-07 30.1 0.1 0.83 9.9 0.0 4.2 3 1 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 TrmB PF01978.14 KFP02792.1 - 4.9e-05 22.9 0.0 0.2 11.3 0.0 2.7 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB CAP_N PF01213.14 KFP02792.1 - 7.3e-05 22.2 0.7 0.00017 21.0 0.5 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal HTH_15 PF12324.3 KFP02792.1 - 0.079 12.6 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase TFIIE_alpha PF02002.12 KFP02792.1 - 0.14 11.7 0.1 0.34 10.4 0.1 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit Mito_fiss_reg PF05308.6 KFP02792.1 - 0.27 10.5 7.8 0.15 11.4 1.1 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator UQ_con PF00179.21 KFP02793.1 - 3.4e-10 39.5 0.0 1.6e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP02793.1 - 0.0011 18.6 0.0 0.0047 16.6 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KFP02793.1 - 0.024 14.5 0.0 2.7 7.9 0.0 2.4 2 1 0 2 2 2 0 RWD domain L27 PF02828.11 KFP02793.1 - 0.047 13.3 0.7 2.2 8.0 0.1 3.2 3 0 0 3 3 3 0 L27 domain RNA_pol_Rpb2_4 PF04566.8 KFP02793.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 KIAA1430 PF13879.1 KFP02793.1 - 1.5 9.2 4.8 4.5 7.7 0.4 2.6 2 1 1 3 3 3 0 KIAA1430 homologue DUF3893 PF13032.1 KFP02794.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) E1-E2_ATPase PF00122.15 KFP02795.1 - 1.5e-16 60.1 0.0 4e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFP02795.1 - 3e-16 60.1 0.0 5.6e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFP02795.1 - 5.4e-12 46.5 0.4 9.1e-05 22.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP02795.1 - 2e-10 40.4 0.0 5.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFP02795.1 - 0.00045 19.8 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TraO PF10626.4 KFP02795.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Conjugative transposon protein TraO MIP PF00230.15 KFP02796.1 - 7.5e-38 130.2 6.9 9.2e-38 129.9 4.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein NICE-3 PF07406.6 KFP02798.1 - 1.2e-44 152.0 0.1 1.7e-44 151.5 0.1 1.2 1 0 0 1 1 1 1 NICE-3 protein Tropomyosin PF00261.15 KFP02799.1 - 7.9e-73 244.4 72.3 3.4e-66 222.7 31.5 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFP02799.1 - 9.5e-37 126.0 61.7 2.1e-35 121.6 30.8 2.1 2 0 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.7 KFP02799.1 - 0.00014 21.6 25.1 0.015 15.0 7.7 2.8 1 1 2 3 3 3 3 Laminin Domain II IncA PF04156.9 KFP02799.1 - 0.00046 19.8 26.7 0.00046 19.8 18.5 2.2 1 1 1 2 2 2 1 IncA protein MscS_porin PF12795.2 KFP02799.1 - 0.057 12.7 40.4 0.19 10.9 4.7 2.6 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF869 PF05911.6 KFP02799.1 - 0.11 10.7 43.8 0.13 10.4 19.6 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) RmuC PF02646.11 KFP02799.1 - 0.19 10.5 24.4 0.14 11.0 3.7 3.1 1 1 2 3 3 3 0 RmuC family Nup54 PF13874.1 KFP02799.1 - 0.25 10.9 30.8 0.46 10.1 2.2 4.0 1 1 3 4 4 4 0 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.4 KFP02799.1 - 0.35 10.7 56.4 0.22 11.3 11.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 KFP02799.1 - 0.55 10.5 10.1 8.9 6.6 0.1 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2514 PF10721.4 KFP02799.1 - 0.82 9.3 35.9 0.036 13.7 18.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2514) TPR_MLP1_2 PF07926.7 KFP02799.1 - 0.82 9.4 48.9 2.1 8.0 7.6 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFP02799.1 - 0.92 8.6 4.9 3.6 6.6 1.0 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KFP02799.1 - 1 9.1 11.1 18 5.1 0.2 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 KFP02799.1 - 1.1 9.2 57.6 0.45 10.4 21.8 3.5 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) EzrA PF06160.7 KFP02799.1 - 1.2 7.1 35.8 1.5 6.9 5.8 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ADIP PF11559.3 KFP02799.1 - 1.5 8.7 42.8 5.4 6.9 8.6 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 KFP02799.1 - 1.5 8.5 22.4 6.8 6.5 3.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Uds1 PF15456.1 KFP02799.1 - 1.7 8.6 42.2 1.9 8.5 1.4 3.8 1 1 3 4 4 4 0 Up-regulated During Septation ERM PF00769.14 KFP02799.1 - 2.1 7.7 58.2 0.33 10.4 4.5 2.8 1 1 0 2 2 2 0 Ezrin/radixin/moesin family WEMBL PF05701.6 KFP02799.1 - 2.3 6.5 56.8 0.13 10.6 6.7 3.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Vps5 PF09325.5 KFP02799.1 - 2.6 7.2 35.3 2 7.6 2.8 3.2 1 1 2 3 3 3 0 Vps5 C terminal like AAA_13 PF13166.1 KFP02799.1 - 3.2 6.0 38.2 1.1 7.6 12.5 2.2 1 1 1 2 2 2 0 AAA domain Laminin_I PF06008.9 KFP02799.1 - 4 6.6 46.5 3 7.1 20.1 3.0 1 1 2 3 3 3 0 Laminin Domain I LOH1CR12 PF10158.4 KFP02799.1 - 4.2 7.1 9.5 8.6 6.1 4.5 2.7 1 1 0 2 2 2 0 Tumour suppressor protein Tweety PF04906.8 KFP02799.1 - 6 5.1 9.4 9 4.5 0.5 3.0 1 1 2 3 3 3 0 Tweety COG2 PF06148.6 KFP02799.1 - 6.5 6.6 25.5 0.2 11.4 2.8 3.6 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.5 KFP02799.1 - 9.7 6.3 21.2 1.8 8.6 6.2 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TRAP_beta PF05753.9 KFP02800.1 - 4.2e-51 172.6 0.0 5e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Cpn60_TCP1 PF00118.19 KFP02801.1 - 6.2e-66 222.9 1.3 6.9e-66 222.8 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RusA PF05866.6 KFP02801.1 - 0.013 15.8 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA DUF1955 PF09205.5 KFP02801.1 - 0.014 14.8 0.4 0.025 14.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) EST1_DNA_bind PF10373.4 KFP02802.1 - 1.7e-33 116.0 0.9 2.4e-33 115.5 0.6 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KFP02802.1 - 2.3e-31 108.5 0.6 2.2e-30 105.3 0.6 2.2 3 0 0 3 3 3 1 Telomerase activating protein Est1 Trypsin PF00089.21 KFP02803.1 - 8.5e-61 205.3 0.2 1e-60 205.0 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFP02803.1 - 0.00011 22.2 0.0 0.00015 21.6 0.0 1.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 KFP02803.1 - 0.00028 20.2 0.0 0.00052 19.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.21 KFP02804.1 - 6.6e-66 222.0 0.1 7.3e-66 221.8 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFP02804.1 - 9.2e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 KFP02804.1 - 0.00013 21.3 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PTS_EIIA_2 PF00359.17 KFP02804.1 - 0.083 12.6 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Trypsin PF00089.21 KFP02805.1 - 6.9e-54 182.7 0.0 7.5e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP02805.1 - 0.00069 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PCI PF01399.22 KFP02806.1 - 2.1e-17 63.3 1.8 4.9e-17 62.1 1.3 1.6 1 0 0 1 1 1 1 PCI domain Cullin PF00888.17 KFP02807.1 - 1.8e-157 525.4 21.3 2.7e-157 524.8 14.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFP02807.1 - 1.4e-26 92.0 0.2 5.2e-26 90.2 0.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Membr_traf_MHD PF10540.4 KFP02807.1 - 0.0064 16.2 0.9 0.62 9.8 0.0 3.6 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain Lamp PF01299.12 KFP02808.1 - 2.7e-118 394.5 9.4 1.8e-113 378.7 5.6 2.0 1 1 1 2 2 2 2 Lysosome-associated membrane glycoprotein (Lamp) RabGAP-TBC PF00566.13 KFP02809.1 - 7.7e-56 188.9 0.1 1.1e-55 188.4 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ndc1_Nup PF09531.5 KFP02810.1 - 8.4 4.6 7.6 9.8 4.4 5.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ADP_ribosyl_GH PF03747.9 KFP02811.1 - 1.7e-41 142.8 0.0 2.1e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Cullin_binding PF03556.10 KFP02812.1 - 2.1e-40 137.5 0.7 2.1e-40 137.5 0.5 2.2 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 KFP02812.1 - 1.9e-09 36.8 1.7 5.4e-09 35.4 0.0 2.6 3 0 0 3 3 3 1 UBA-like domain Na_H_Exchanger PF00999.16 KFP02813.1 - 2.2e-73 246.9 42.3 3e-73 246.5 29.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF16 PF01519.11 KFP02813.1 - 1.5 9.0 5.9 3.1 8.0 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF373 PF04123.8 KFP02813.1 - 5 6.0 15.8 0.97 8.3 7.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Fib_alpha PF08702.5 KFP02813.1 - 8.6 6.4 7.2 3.6 7.7 2.8 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DP PF08781.5 KFP02814.1 - 9.5e-58 193.9 2.2 9.5e-58 193.9 1.5 1.7 2 0 0 2 2 2 1 Transcription factor DP E2F_TDP PF02319.15 KFP02814.1 - 4.4e-27 93.4 0.3 1.1e-26 92.2 0.2 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FAM70 PF14967.1 KFP02815.1 - 1.5e-176 586.3 8.5 1.7e-176 586.2 5.9 1.0 1 0 0 1 1 1 1 FAM70 protein DUF4064 PF13273.1 KFP02815.1 - 0.0056 16.7 11.5 0.44 10.6 5.5 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) DUF2407_C PF13373.1 KFP02815.1 - 0.44 10.4 2.4 4.5 7.1 0.7 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF1097 PF06496.6 KFP02815.1 - 1.1 9.0 12.0 5.8 6.7 4.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1097) DUF2371 PF10177.4 KFP02815.1 - 1.7 8.5 3.6 37 4.1 0.3 3.0 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) Laminin_G_1 PF00054.18 KFP02816.1 - 7.6e-30 103.6 0.0 4.6e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain Laminin_G_2 PF02210.19 KFP02816.1 - 1.5e-28 99.3 0.0 3.9e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain EGF_CA PF07645.10 KFP02816.1 - 4.6e-22 77.7 52.5 3.5e-08 33.3 4.8 5.0 4 0 0 4 4 4 4 Calcium-binding EGF domain Gla PF00594.15 KFP02816.1 - 6e-15 54.6 8.9 1.4e-14 53.4 6.2 1.7 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain cEGF PF12662.2 KFP02816.1 - 4.6e-14 51.7 30.4 2.8e-07 30.0 2.0 5.0 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFP02816.1 - 1.7e-13 50.4 60.0 1.4e-08 34.7 7.7 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFP02816.1 - 5.9e-11 42.1 44.7 0.00047 20.0 4.3 4.7 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.2 KFP02816.1 - 0.00011 22.0 45.9 0.01 15.7 3.2 4.7 4 0 0 4 4 4 3 EGF domain Apc3 PF12895.2 KFP02817.1 - 4.1e-27 94.1 13.0 5.1e-19 68.2 6.9 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KFP02817.1 - 1.2e-26 92.0 20.9 6.9e-14 51.2 0.1 7.3 6 2 0 8 8 8 5 TPR repeat TPR_2 PF07719.12 KFP02817.1 - 1.7e-25 86.8 19.1 6.9e-06 25.5 0.1 10.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFP02817.1 - 1.2e-21 75.3 20.2 4.2e-08 32.4 0.1 8.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFP02817.1 - 2.2e-21 75.5 0.7 4.9e-12 45.6 0.3 7.3 3 2 2 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP02817.1 - 6.9e-16 56.7 5.1 0.011 15.4 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP02817.1 - 1.7e-15 57.0 1.8 0.011 16.0 0.0 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFP02817.1 - 6.7e-13 47.3 7.1 1.9e-05 24.1 0.1 5.2 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP02817.1 - 7.3e-13 48.8 12.4 0.00024 21.6 0.0 5.8 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP02817.1 - 9.2e-12 44.5 7.2 1.1 10.0 0.0 8.2 6 3 2 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP02817.1 - 1.4e-11 43.6 1.6 0.025 14.7 0.0 5.9 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFP02817.1 - 4.2e-11 42.3 0.4 0.00014 21.6 0.2 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP02817.1 - 1.5e-08 34.3 6.6 0.0075 16.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat APC8 PF04049.8 KFP02817.1 - 0.051 13.3 3.6 0.098 12.3 1.7 2.2 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_3 PF07720.7 KFP02817.1 - 0.16 11.8 6.6 6 6.7 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFP02817.1 - 0.17 12.4 15.9 3.1 8.4 0.2 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFP02817.1 - 0.52 10.2 9.2 0.99 9.3 0.2 4.2 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Smg4_UPF3 PF03467.10 KFP02818.1 - 1.3e-55 188.0 0.1 1.3e-55 188.0 0.0 2.5 2 1 1 3 3 3 1 Smg-4/UPF3 family zf-H2C2_2 PF13465.1 KFP02819.1 - 0.00092 19.3 0.6 0.00092 19.3 0.4 5.8 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFP02819.1 - 0.0099 16.1 0.1 0.0099 16.1 0.1 5.3 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KFP02819.1 - 0.041 14.1 0.2 0.041 14.1 0.1 5.4 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KFP02819.1 - 0.18 12.2 0.0 0.18 12.2 0.0 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger Septin PF00735.13 KFP02820.1 - 3e-95 318.4 0.6 3e-95 318.4 0.4 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFP02820.1 - 0.00016 21.5 0.0 0.00042 20.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFP02820.1 - 0.0003 20.8 0.2 0.00079 19.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFP02820.1 - 0.0011 19.0 0.1 0.0066 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFP02820.1 - 0.0019 18.6 1.9 0.047 14.1 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KFP02820.1 - 0.0038 16.7 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 KFP02820.1 - 0.0089 15.2 0.3 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFP02820.1 - 0.03 13.7 2.4 4.9 6.5 0.3 3.0 1 1 2 3 3 3 0 Elongation factor Tu GTP binding domain T2SE PF00437.15 KFP02820.1 - 0.03 13.2 0.0 0.074 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KFP02820.1 - 0.063 12.7 1.9 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KFP02820.1 - 0.081 13.2 0.5 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 KFP02820.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KFP02820.1 - 0.24 11.7 3.3 1.8 8.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 KFP02820.1 - 0.72 9.6 0.0 0.72 9.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 KFP02820.1 - 1.7 8.4 5.3 1.2 8.9 0.1 2.4 2 1 0 2 2 2 0 Dynamin family OmpH PF03938.9 KFP02820.1 - 4.2 7.2 16.1 7.8 6.4 11.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Death PF00531.17 KFP02822.1 - 6.9e-05 22.5 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 Death domain DUF4199 PF13858.1 KFP02822.1 - 0.016 15.1 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF1510 PF07423.6 KFP02822.1 - 0.02 14.2 2.5 0.031 13.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TNFR_c6 PF00020.13 KFP02822.1 - 0.032 14.2 16.3 0.053 13.5 5.7 3.7 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region PIG-P PF08510.7 KFP02822.1 - 0.17 11.4 3.0 0.25 10.9 1.2 1.9 2 1 0 2 2 2 0 PIG-P DUF912 PF06024.7 KFP02822.1 - 0.46 10.5 5.6 0.2 11.7 0.4 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pro_isomerase PF00160.16 KFP02824.1 - 1.6e-41 142.0 1.1 1.9e-41 141.8 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ran_BP1 PF00638.13 KFP02825.1 - 3.6e-57 191.6 0.6 4.2e-57 191.5 0.4 1.0 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KFP02825.1 - 4.6e-05 23.0 0.1 8.4e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 WH1 domain TPR_2 PF07719.12 KFP02826.1 - 2e-09 36.6 0.2 1.1e-05 24.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP02826.1 - 2.3e-08 33.3 0.1 2.9e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP02826.1 - 2.5e-07 30.7 0.0 0.024 15.2 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFP02826.1 - 4.7e-07 29.3 1.2 6.4e-05 22.5 0.1 2.4 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 KFP02826.1 - 2.8e-05 23.5 0.0 0.0016 18.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFP02826.1 - 3e-05 23.8 0.2 0.3 11.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP02826.1 - 0.0011 18.6 0.1 0.082 12.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP02826.1 - 0.002 18.4 0.4 0.65 10.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP02826.1 - 0.0059 16.5 0.1 0.1 12.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Sel1 PF08238.7 KFP02826.1 - 0.054 14.1 0.0 19 6.0 0.0 2.6 2 0 0 2 2 2 0 Sel1 repeat TPR_16 PF13432.1 KFP02826.1 - 0.12 13.1 0.2 42 4.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LIM PF00412.17 KFP02827.1 - 3e-62 206.5 62.6 2.8e-14 52.9 2.1 5.1 5 0 0 5 5 5 5 LIM domain DUF4428 PF14471.1 KFP02827.1 - 0.018 14.7 3.6 0.018 14.7 2.5 6.3 6 1 0 6 6 6 0 Domain of unknown function (DUF4428) CagZ PF09053.5 KFP02827.1 - 0.14 11.4 0.4 0.64 9.3 0.0 1.9 2 0 0 2 2 2 0 CagZ GRIP PF01465.15 KFP02828.1 - 1.5e-16 59.5 0.3 5.4e-16 57.8 0.2 2.1 1 0 0 1 1 1 1 GRIP domain HOOK PF05622.7 KFP02828.1 - 0.0005 18.0 13.7 0.0005 18.0 9.5 7.5 1 1 6 7 7 7 3 HOOK protein Sulfotransfer_1 PF00685.22 KFP02829.1 - 9.9e-92 306.9 1.6 1.2e-91 306.7 1.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain SSF PF00474.12 KFP02830.1 - 4.1e-34 117.9 31.3 5.7e-34 117.4 21.7 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Alpha_GJ PF03229.8 KFP02830.1 - 0.2 12.0 2.2 0.91 9.8 0.4 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J Glyco_transf_29 PF00777.13 KFP02831.1 - 5.5e-68 229.0 0.0 3.8e-67 226.2 0.0 1.9 1 1 1 2 2 2 1 Glycosyltransferase family 29 (sialyltransferase) fn3 PF00041.16 KFP02832.1 - 3e-86 283.6 0.0 1.3e-18 66.8 0.0 6.1 5 0 0 5 5 5 5 Fibronectin type III domain I-set PF07679.11 KFP02832.1 - 1.7e-62 207.2 3.9 1.1e-17 63.6 0.2 7.8 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP02832.1 - 2e-30 104.7 2.2 4.5e-06 26.6 0.0 7.3 7 0 0 7 7 7 6 Immunoglobulin domain V-set PF07686.12 KFP02832.1 - 2.1e-22 79.1 11.5 2.1e-06 27.6 0.1 8.8 7 3 0 7 7 7 5 Immunoglobulin V-set domain ig PF00047.20 KFP02832.1 - 5.2e-17 61.7 7.2 0.00031 20.8 0.0 7.4 7 0 0 7 7 7 4 Immunoglobulin domain Ig_3 PF13927.1 KFP02832.1 - 4.3e-12 46.3 0.3 0.038 14.4 0.0 5.9 6 0 0 6 6 6 3 Immunoglobulin domain C2-set_2 PF08205.7 KFP02832.1 - 3.6e-08 33.2 0.0 0.029 14.2 0.0 4.7 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Tissue_fac PF01108.12 KFP02832.1 - 2.7e-06 27.0 0.2 1.6 8.4 0.0 5.1 5 0 0 5 5 5 2 Tissue factor Interfer-bind PF09294.5 KFP02832.1 - 6.4e-06 26.1 0.1 4 7.5 0.0 4.8 5 0 0 5 5 5 2 Interferon-alpha/beta receptor, fibronectin type III SusE PF14292.1 KFP02832.1 - 0.0083 15.9 0.0 1.4 8.7 0.0 4.1 4 0 0 4 4 4 1 SusE outer membrane protein RRM_1 PF00076.17 KFP02833.1 - 1.5e-10 40.5 0.0 3.4e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02833.1 - 1.5e-08 34.4 0.0 2.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP02833.1 - 2.7e-06 27.1 0.0 4.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PNRC PF15365.1 KFP02834.1 - 5.1e-21 74.4 10.5 2.4e-20 72.2 2.8 2.4 2 0 0 2 2 2 2 Proline-rich nuclear receptor coactivator Ribosomal_S20p PF01649.13 KFP02834.1 - 0.034 14.5 4.4 0.054 13.8 3.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 DUF3824 PF12868.2 KFP02834.1 - 2.1 9.2 6.2 3 8.7 4.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) 7tm_1 PF00001.16 KFP02835.1 - 1.8e-44 151.8 23.2 2.4e-44 151.4 16.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3169 PF11368.3 KFP02835.1 - 0.23 10.6 7.6 3.1 6.9 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Alpha_L_fucos PF01120.12 KFP02836.1 - 1.8e-86 290.2 1.1 2.1e-86 289.9 0.8 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Pacifastin_I PF05375.8 KFP02836.1 - 0.11 12.0 2.7 0.2 11.2 1.9 1.3 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) HMGL-like PF00682.14 KFP02837.1 - 1.6e-73 247.2 0.2 1.9e-73 247.0 0.1 1.0 1 0 0 1 1 1 1 HMGL-like Terminase_2 PF03592.11 KFP02837.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Terminase small subunit IGFBP PF00219.13 KFP02838.1 - 2.6e-13 50.2 23.2 2.6e-13 50.2 16.1 6.0 3 2 1 4 4 4 1 Insulin-like growth factor binding protein Cys_knot PF00007.17 KFP02838.1 - 1.1e-12 48.0 7.5 1.1e-12 48.0 5.2 3.8 4 0 0 4 4 4 1 Cystine-knot domain TSP_1 PF00090.14 KFP02838.1 - 1.8e-10 40.7 6.8 1.8e-10 40.7 4.7 3.4 2 1 0 2 2 2 1 Thrombospondin type 1 domain VWC PF00093.13 KFP02838.1 - 1.5e-08 34.5 10.0 1.5e-08 34.5 7.0 5.2 4 3 1 5 5 5 1 von Willebrand factor type C domain 4_1_CTD PF05902.8 KFP02839.1 - 1e-53 180.2 12.6 1e-53 180.2 8.7 2.0 2 0 0 2 2 2 1 4.1 protein C-terminal domain (CTD) SAB PF04382.8 KFP02839.1 - 1.7e-27 94.8 3.0 4.5e-27 93.4 2.0 1.8 1 0 0 1 1 1 1 SAB domain FERM_C PF09380.5 KFP02839.1 - 3.4e-23 81.6 0.0 8.1e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFP02839.1 - 3.7e-21 74.9 0.1 2.3e-20 72.4 0.0 2.3 2 0 0 2 2 2 1 FERM N-terminal domain FERM_M PF00373.13 KFP02839.1 - 2e-20 73.2 1.3 6.4e-20 71.5 0.0 2.5 2 0 0 2 2 2 1 FERM central domain FA PF08736.6 KFP02839.1 - 7.6e-19 67.2 2.0 1.9e-18 65.9 1.4 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) MBT PF02820.13 KFP02840.1 - 3.4e-94 308.8 0.7 8.7e-32 108.8 0.0 3.1 3 0 0 3 3 3 3 mbt repeat zf-C2HC PF01530.13 KFP02840.1 - 7e-13 48.0 11.9 1.5e-12 47.0 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2HC type Glyco_hydro_2_N PF02837.13 KFP02840.1 - 0.00081 18.9 0.1 1.6 8.2 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 2, sugar binding domain Tudor-knot PF11717.3 KFP02840.1 - 0.11 12.2 6.1 0.36 10.5 0.4 3.0 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain RRM_1 PF00076.17 KFP02842.1 - 2.7e-22 78.1 0.0 2.7e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02842.1 - 3.7e-12 46.0 0.0 1.7e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP02842.1 - 1.6e-10 40.6 0.0 9.4e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP02842.1 - 1.7e-05 24.5 2.3 2.4e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 RNA binding motif ADH_zinc_N PF00107.21 KFP02843.1 - 7e-18 64.4 0.0 1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFP02843.1 - 1.1e-09 38.0 0.1 2.6e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFP02843.1 - 1.3e-06 29.3 0.0 2.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDPD_2 PF13653.1 KFP02843.1 - 0.02 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Y_phosphatase PF00102.22 KFP02844.1 - 3.9e-140 464.9 1.2 4.7e-80 268.3 0.1 2.5 3 0 0 3 3 3 2 Protein-tyrosine phosphatase MAM PF00629.18 KFP02844.1 - 3.5e-38 130.8 0.0 7.5e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 MAM domain fn3 PF00041.16 KFP02844.1 - 4.3e-31 106.8 0.9 4.3e-12 46.0 0.0 4.9 5 0 0 5 5 5 3 Fibronectin type III domain DSPc PF00782.15 KFP02844.1 - 9.8e-07 28.4 0.9 0.03 13.8 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP02844.1 - 2.4e-05 24.6 0.2 0.044 14.0 0.0 2.6 2 0 0 2 2 2 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP02844.1 - 5.2e-05 23.3 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 2 Inositol hexakisphosphate Ig_2 PF13895.1 KFP02844.1 - 0.00023 21.2 0.0 0.0007 19.6 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP02844.1 - 0.03 14.1 0.0 0.075 12.8 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin I-set domain VWA PF00092.23 KFP02845.1 - 7.5e-99 328.7 5.1 4.8e-51 172.9 0.4 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KFP02845.1 - 3.5e-32 111.8 0.3 3.2e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Matrilin_ccoil PF10393.4 KFP02845.1 - 4.1e-11 42.0 1.8 8e-11 41.1 0.5 2.1 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin FXa_inhibition PF14670.1 KFP02845.1 - 2.3e-09 37.1 7.4 2.3e-09 37.1 5.1 1.7 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP02845.1 - 1.8e-06 27.4 1.0 4.4e-06 26.2 0.7 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_CA PF07645.10 KFP02845.1 - 3.4e-06 26.9 5.7 7.3e-06 25.8 3.9 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.22 KFP02845.1 - 0.0059 16.5 3.8 0.013 15.4 2.6 1.6 1 0 0 1 1 1 1 EGF-like domain DUF2242 PF10001.4 KFP02845.1 - 0.058 13.2 1.4 4.2 7.2 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2242) EGF_3 PF12947.2 KFP02845.1 - 3.2 7.8 12.8 0.22 11.5 5.3 1.8 2 0 0 2 2 2 0 EGF domain Mtp PF03821.11 KFP02846.1 - 4.5e-67 225.8 16.3 5e-67 225.7 11.3 1.0 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter CybS PF05328.7 KFP02846.1 - 0.28 10.7 3.6 2.4 7.7 0.2 2.5 2 0 0 2 2 2 0 CybS DUF1211 PF06736.6 KFP02846.1 - 0.97 9.6 8.7 0.37 10.9 0.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) ABC2_membrane_2 PF12679.2 KFP02846.1 - 2.8 6.7 10.9 4 6.2 7.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Syndecan PF01034.15 KFP02847.1 - 1.3e-32 111.2 0.2 1.9e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain DUF3816 PF12822.2 KFP02847.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) PUF PF00806.14 KFP02848.1 - 1.2e-73 238.6 8.3 4.6e-09 35.2 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.6 KFP02848.1 - 1.1 9.1 5.6 2.7 7.8 0.0 3.6 3 1 1 4 4 4 0 CPL (NUC119) domain NKAIN PF05640.9 KFP02849.1 - 1.4e-85 285.3 6.1 1.5e-85 285.2 4.2 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Vmethyltransf_C PF08456.5 KFP02849.1 - 0.28 10.5 1.0 0.42 10.0 0.7 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF3974 PF13120.1 KFP02850.1 - 0.03 14.1 0.1 0.074 12.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) Peptidase_M48 PF01435.13 KFP02851.1 - 2.3e-76 256.2 0.0 3e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 DUF4344 PF14247.1 KFP02851.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Amino_oxidase PF01593.19 KFP02852.1 - 4e-164 546.9 0.0 4.7e-164 546.7 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KFP02852.1 - 3e-20 72.1 0.3 3.4e-19 68.7 0.0 2.6 3 0 0 3 3 3 1 SWIRM domain NAD_binding_8 PF13450.1 KFP02852.1 - 6.2e-15 54.9 0.5 1.3e-14 53.9 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFP02852.1 - 7.5e-08 31.6 0.0 4.5e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFP02852.1 - 2.5e-07 30.9 0.5 1.3e-05 25.4 0.2 3.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFP02852.1 - 4.5e-05 22.4 1.7 5e-05 22.3 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 KFP02852.1 - 8.7e-05 22.1 0.3 0.00021 20.9 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 KFP02852.1 - 9.1e-05 22.4 0.7 0.00029 20.7 0.3 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFP02852.1 - 0.0004 20.4 1.8 0.0016 18.5 0.1 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFP02852.1 - 0.00051 19.1 0.5 0.00092 18.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFP02852.1 - 0.00067 18.2 0.3 0.00067 18.2 0.2 2.3 1 1 1 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KFP02852.1 - 0.00098 18.2 0.1 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family 2-Hacid_dh_C PF02826.14 KFP02852.1 - 0.018 14.2 0.2 0.07 12.2 0.1 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KFP02852.1 - 0.025 13.6 4.8 0.014 14.5 1.3 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KFP02852.1 - 0.038 12.8 5.4 0.09 11.6 0.2 2.2 1 1 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.7 KFP02852.1 - 0.096 12.0 0.9 0.39 10.0 0.6 2.0 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF1465 PF07323.7 KFP02852.1 - 0.13 11.8 3.4 0.14 11.6 0.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1465) Lycopene_cycl PF05834.7 KFP02852.1 - 0.16 10.8 0.2 0.43 9.4 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein MutS_IV PF05190.13 KFP02852.1 - 0.21 11.8 3.5 1.1 9.4 0.4 2.5 2 0 0 2 2 2 0 MutS family domain IV SlyX PF04102.7 KFP02852.1 - 0.78 10.1 5.2 2.8 8.3 1.7 2.6 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.14 KFP02852.1 - 1.4 6.6 4.6 2.3 5.9 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KFP02852.1 - 1.5 8.4 7.5 15 5.1 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator Nnf1 PF03980.9 KFP02852.1 - 2.1 8.3 10.1 4.1 7.4 7.0 1.5 1 0 0 1 1 1 0 Nnf1 AATF-Che1 PF13339.1 KFP02852.1 - 2.8 8.0 8.6 1.8 8.7 3.6 2.4 2 1 1 3 3 2 0 Apoptosis antagonizing transcription factor IncA PF04156.9 KFP02852.1 - 3.3 7.2 13.2 3.5 7.1 8.3 1.6 1 1 0 1 1 1 0 IncA protein DUF3782 PF12644.2 KFP02852.1 - 5.5 6.8 8.6 1.9e+03 -1.3 5.9 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Viral_P18 PF04521.8 KFP02852.1 - 7.1 6.1 8.1 2.1 7.8 2.6 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Snapin_Pallidin PF14712.1 KFP02852.1 - 7.4 6.9 10.5 3.4 8.0 2.8 2.4 1 1 0 2 2 2 0 Snapin/Pallidin 7tm_1 PF00001.16 KFP02853.1 - 2.1e-85 285.9 15.1 2.5e-85 285.6 10.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP02853.1 - 1.1e-10 41.1 10.6 4.3e-10 39.1 7.3 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP02853.1 - 0.0016 17.5 9.2 0.0016 17.5 6.4 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx T2SL PF05134.8 KFP02853.1 - 0.018 14.1 0.2 0.031 13.4 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L RRM_1 PF00076.17 KFP02855.1 - 2.6e-45 151.8 0.8 2.3e-15 55.9 0.3 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02855.1 - 1.2e-35 121.2 0.1 1.7e-12 47.1 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP02855.1 - 3.2e-18 65.3 0.1 1.1e-05 25.2 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFP02855.1 - 0.00012 21.7 1.2 0.46 10.2 0.2 3.9 1 1 2 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 KFP02855.1 - 0.0085 15.8 0.0 1.8 8.3 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 KFP02855.1 - 0.012 15.2 0.2 0.28 10.7 0.1 2.6 2 1 1 3 3 3 0 Calcipressin IATP PF04568.7 KFP02856.1 - 3e-08 33.6 11.6 3e-08 33.6 8.0 1.6 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.10 KFP02856.1 - 0.0052 16.2 4.9 0.0052 16.2 3.4 1.5 1 1 0 1 1 1 1 Septum formation initiator Phage_lysis PF03245.8 KFP02856.1 - 0.015 15.2 4.4 0.015 15.2 3.1 1.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein TMF_DNA_bd PF12329.3 KFP02856.1 - 0.02 14.7 8.6 0.05 13.4 6.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 KFP02856.1 - 0.022 14.8 3.5 0.022 14.8 2.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 KFP02856.1 - 0.033 13.4 2.7 0.032 13.4 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Val_tRNA-synt_C PF10458.4 KFP02856.1 - 0.043 13.8 2.6 0.043 13.8 1.8 2.0 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Prefoldin_2 PF01920.15 KFP02856.1 - 0.047 13.4 8.6 0.049 13.3 5.9 1.1 1 0 0 1 1 1 0 Prefoldin subunit THOC7 PF05615.8 KFP02856.1 - 0.059 13.6 7.7 0.062 13.5 5.3 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 DUF2968 PF11180.3 KFP02856.1 - 0.061 12.6 3.2 0.062 12.6 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.6 KFP02856.1 - 0.074 11.7 6.1 0.072 11.7 4.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Sipho_Gp157 PF05565.6 KFP02856.1 - 0.079 12.5 6.4 0.08 12.5 4.4 1.0 1 0 0 1 1 1 0 Siphovirus Gp157 ADIP PF11559.3 KFP02856.1 - 0.13 12.1 6.7 0.13 12.1 4.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 KFP02856.1 - 0.14 12.0 0.8 0.17 11.8 0.6 1.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF812 PF05667.6 KFP02856.1 - 0.15 10.5 5.7 0.15 10.5 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DNA_Packaging_2 PF11123.3 KFP02856.1 - 0.16 11.8 1.2 0.21 11.4 0.8 1.5 1 1 0 1 1 1 0 DNA packaging protein Transcrip_act PF04949.8 KFP02856.1 - 0.19 11.3 3.6 0.19 11.3 2.5 1.0 1 0 0 1 1 1 0 Transcriptional activator FlxA PF14282.1 KFP02856.1 - 0.25 11.3 2.2 0.31 10.9 0.8 1.3 1 1 0 1 1 1 0 FlxA-like protein ABC_tran_2 PF12848.2 KFP02856.1 - 0.3 10.9 9.7 0.48 10.3 6.7 1.4 1 1 0 1 1 1 0 ABC transporter DUF4140 PF13600.1 KFP02856.1 - 0.32 11.4 4.8 0.38 11.2 3.3 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1409 PF07197.7 KFP02856.1 - 0.34 10.9 5.2 0.52 10.4 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1409) Dzip-like_N PF13815.1 KFP02856.1 - 0.35 10.6 6.6 0.36 10.6 4.6 1.0 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal CCDC155 PF14662.1 KFP02856.1 - 0.37 10.3 6.2 0.36 10.3 4.3 1.0 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF1192 PF06698.6 KFP02856.1 - 0.38 10.5 4.0 0.61 9.9 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Bap31 PF05529.7 KFP02856.1 - 0.47 9.8 6.5 0.47 9.8 4.5 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like AAA_13 PF13166.1 KFP02856.1 - 0.48 8.8 5.1 0.46 8.8 3.5 1.0 1 0 0 1 1 1 0 AAA domain Spectrin PF00435.16 KFP02856.1 - 0.54 10.5 6.9 0.56 10.5 4.8 1.1 1 0 0 1 1 1 0 Spectrin repeat ATG16 PF08614.6 KFP02856.1 - 0.58 9.9 6.7 0.59 9.9 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1640 PF07798.6 KFP02856.1 - 0.69 9.9 5.2 0.73 9.8 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4407 PF14362.1 KFP02856.1 - 0.7 8.7 2.5 0.68 8.8 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.16 KFP02856.1 - 0.71 9.8 6.1 0.95 9.4 4.2 1.3 1 1 0 1 1 1 0 bZIP transcription factor DUF641 PF04859.7 KFP02856.1 - 0.74 9.5 4.8 0.74 9.5 3.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Lipoprotein_20 PF13942.1 KFP02856.1 - 0.79 9.2 6.0 0.8 9.2 4.2 1.0 1 0 0 1 1 1 0 YfhG lipoprotein DUF2681 PF10883.3 KFP02856.1 - 0.84 9.8 5.5 2.6 8.2 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Borrelia_P83 PF05262.6 KFP02856.1 - 0.88 7.7 8.1 0.87 7.7 5.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein KfrA_N PF11740.3 KFP02856.1 - 1 9.8 3.6 0.96 9.9 2.5 1.0 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF342 PF03961.8 KFP02856.1 - 1 7.7 5.7 1.1 7.6 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4391 PF14335.1 KFP02856.1 - 1.1 8.6 5.8 1.2 8.4 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) PCRF PF03462.13 KFP02856.1 - 1.1 8.9 3.6 1.1 9.0 2.5 1.1 1 0 0 1 1 1 0 PCRF domain DUF4200 PF13863.1 KFP02856.1 - 1.3 9.0 12.2 1.4 8.8 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IMD PF08397.6 KFP02856.1 - 1.3 8.2 7.8 1.3 8.2 5.4 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF4446 PF14584.1 KFP02856.1 - 1.4 8.7 3.7 1.3 8.8 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) G-gamma PF00631.17 KFP02856.1 - 1.6 8.5 5.1 0.2 11.4 1.0 1.4 2 0 0 2 2 1 0 GGL domain bZIP_Maf PF03131.12 KFP02856.1 - 1.6 9.0 6.2 1.7 8.9 4.3 1.0 1 0 0 1 1 1 0 bZIP Maf transcription factor Atg14 PF10186.4 KFP02856.1 - 1.7 7.5 9.2 1.7 7.5 6.4 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pox_A_type_inc PF04508.7 KFP02856.1 - 2.1 8.3 7.5 0.44 10.4 1.0 2.6 2 2 1 3 3 3 0 Viral A-type inclusion protein repeat FimP PF09766.4 KFP02856.1 - 2.1 7.2 7.9 2.4 7.1 5.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein TMPIT PF07851.8 KFP02856.1 - 2.2 7.2 4.8 2.2 7.2 3.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein GrpE PF01025.14 KFP02856.1 - 2.5 7.6 6.6 2.5 7.6 4.6 1.0 1 0 0 1 1 1 0 GrpE HAUS5 PF14817.1 KFP02856.1 - 2.7 6.4 6.7 2.7 6.4 4.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF3987 PF13148.1 KFP02856.1 - 3.1 6.2 7.5 3.3 6.1 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) IncA PF04156.9 KFP02856.1 - 3.8 7.0 6.9 4 6.9 4.8 1.1 1 0 0 1 1 1 0 IncA protein DUF244 PF03112.9 KFP02856.1 - 3.9 7.0 7.1 4 6.9 4.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF4078 PF13300.1 KFP02856.1 - 5.8 7.1 9.4 6.3 6.9 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) XhlA PF10779.4 KFP02856.1 - 6.1 6.8 7.2 7.2 6.6 5.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA CENP-Q PF13094.1 KFP02856.1 - 6.4 6.7 9.0 7.5 6.5 6.3 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 KFP02856.1 - 6.5 5.7 7.6 6.4 5.7 5.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4355 PF14265.1 KFP02856.1 - 9.1 6.2 10.2 11 5.9 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DnaJ PF00226.26 KFP02857.1 - 7.7e-19 67.1 1.7 2.5e-18 65.5 1.2 1.9 1 0 0 1 1 1 1 DnaJ domain DUF4320 PF14208.1 KFP02857.1 - 0.023 14.6 1.6 0.039 13.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) RPT PF13446.1 KFP02857.1 - 0.044 13.2 0.1 0.13 11.7 0.1 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein Cytochrom_C1 PF02167.10 KFP02857.1 - 0.81 9.3 7.0 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C1 family AAA_11 PF13086.1 KFP02857.1 - 2.7 7.4 7.8 3.5 7.1 5.4 1.3 1 0 0 1 1 1 0 AAA domain 7tm_1 PF00001.16 KFP02858.1 - 4.1e-48 163.7 23.1 6.4e-48 163.1 16.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Serpentine_r_xa PF03383.10 KFP02858.1 - 0.0082 15.9 23.8 0.02 14.6 0.6 3.2 2 1 0 3 3 3 2 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Str PF10326.4 KFP02858.1 - 8.3 5.4 27.7 8e+02 -1.1 19.2 3.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Proho_convert PF12177.3 KFP02859.1 - 0.063 12.8 0.1 0.063 12.8 0.1 1.9 2 0 0 2 2 2 0 Prohormone convertase enzyme DUF2592 PF10766.4 KFP02859.1 - 0.066 12.5 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) XK-related PF09815.4 KFP02860.1 - 5.6e-84 281.9 12.5 6.3e-84 281.8 8.7 1.0 1 0 0 1 1 1 1 XK-related protein Metallophos PF00149.23 KFP02861.1 - 6.2e-12 45.3 0.4 9.9e-12 44.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RPA_C PF08784.6 KFP02862.1 - 3e-24 85.3 0.0 7.1e-24 84.1 0.0 1.6 1 1 1 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KFP02862.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Syntaxin_2 PF14523.1 KFP02863.1 - 1.5e-22 79.5 13.8 4.5e-22 77.9 5.6 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KFP02863.1 - 3.8e-21 74.5 5.0 3.8e-21 74.5 3.5 2.3 2 0 0 2 2 2 1 SNARE domain Herpes_US9 PF06072.6 KFP02863.1 - 0.00023 20.9 0.1 0.00054 19.7 0.1 1.6 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 Prominin PF05478.6 KFP02863.1 - 0.003 15.2 6.1 0.0067 14.0 0.2 2.0 2 0 0 2 2 2 2 Prominin TBPIP PF07106.8 KFP02863.1 - 0.006 16.1 4.1 0.006 16.1 2.8 2.1 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mit_KHE1 PF10173.4 KFP02863.1 - 0.74 9.6 5.8 1.3 8.8 3.9 1.4 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF1212 PF06738.7 KFP02863.1 - 0.97 8.8 3.2 4.8 6.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) Synaptobrevin PF00957.16 KFP02863.1 - 1.2 8.7 9.0 0.19 11.3 1.4 2.6 2 1 0 2 2 2 0 Synaptobrevin Noelin-1 PF12308.3 KFP02863.1 - 5.4 6.8 7.2 15 5.4 0.3 2.8 2 2 1 3 3 3 0 Neurogenesis glycoprotein MBT PF02820.13 KFP02864.1 - 7.6e-60 198.7 0.0 7.1e-30 102.7 0.0 2.4 2 0 0 2 2 2 2 mbt repeat DUF3588 PF12140.3 KFP02864.1 - 1.3e-47 160.7 0.3 2.1e-47 160.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) GATase PF00117.23 KFP02865.1 - 3.8e-52 176.5 0.0 5.1e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.9 KFP02865.1 - 1e-27 96.9 0.0 1.4e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.8 KFP02865.1 - 1.2e-10 41.2 0.1 2.8e-10 40.0 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 Transket_pyr PF02779.19 KFP02865.1 - 0.034 13.6 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain CITED PF04487.7 KFP02866.1 - 2.4e-83 279.6 14.3 2.6e-83 279.4 9.9 1.0 1 0 0 1 1 1 1 CITED DUF39 PF01837.11 KFP02866.1 - 0.096 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF39 rve PF00665.21 KFP02867.1 - 8.5e-29 100.1 0.0 1.2e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 KFP02867.1 - 3.3e-09 36.0 0.1 8.6e-09 34.7 0.1 1.8 1 0 0 1 1 1 1 Integrase Zinc binding domain DDE_Tnp_IS240 PF13610.1 KFP02867.1 - 0.0052 16.7 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.1 KFP02867.1 - 0.0055 16.2 0.1 0.03 13.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF4496 PF14908.1 KFP02868.1 - 6.4e-12 45.5 0.0 7.2e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) RVT_1 PF00078.22 KFP02869.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lig_chan PF00060.21 KFP02870.1 - 2e-28 98.9 0.4 5.6e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFP02870.1 - 1.1e-23 83.6 0.0 1.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFP02870.1 - 1.9e-19 69.3 0.9 6.1e-19 67.7 0.6 1.9 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site zf-C3HC4_3 PF13920.1 KFP02871.1 - 8.2e-06 25.3 11.6 1.4e-05 24.6 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP02871.1 - 5.9e-05 22.6 14.6 0.00011 21.7 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP02871.1 - 0.00016 21.5 14.4 0.00029 20.8 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP02871.1 - 0.00077 19.1 13.7 0.0036 17.0 9.9 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP02871.1 - 0.021 14.6 14.5 0.078 12.8 10.3 1.8 1 1 1 2 2 2 0 Ring finger domain zf-RING_6 PF14835.1 KFP02871.1 - 0.062 13.0 2.8 0.13 12.0 1.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFP02871.1 - 0.46 10.2 8.3 1.4 8.6 5.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 KFP02871.1 - 0.49 10.2 4.8 0.9 9.4 3.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFP02871.1 - 0.6 10.0 9.5 1.4 8.8 6.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glycolytic PF00274.14 KFP02873.1 - 2.4e-170 565.5 0.1 2.7e-170 565.3 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ribosomal_L50 PF10501.4 KFP02874.1 - 1.1e-21 76.8 0.6 4.4e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal subunit 39S PAP2 PF01569.16 KFP02875.1 - 2.5e-15 56.3 0.5 4.6e-15 55.4 0.4 1.4 1 0 0 1 1 1 1 PAP2 superfamily UCH PF00443.24 KFP02876.1 - 6.5e-51 172.9 0.0 8.8e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP02876.1 - 1e-23 84.2 0.0 1.3e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KFP02876.1 - 0.86 8.8 5.1 0.68 9.1 0.9 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yae1_N PF09811.4 KFP02878.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Peptidase_S49_N PF08496.5 KFP02879.1 - 2.3 7.9 9.2 3.7 7.3 6.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ank_2 PF12796.2 KFP02880.1 - 3.4e-47 158.6 6.8 1.1e-18 67.3 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP02880.1 - 5.1e-46 152.2 11.9 3.2e-10 39.3 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KFP02880.1 - 1.1e-41 140.4 8.6 1.7e-10 41.1 0.1 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP02880.1 - 6e-39 131.1 13.2 1.8e-10 40.6 0.0 6.9 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP02880.1 - 7.4e-30 100.0 6.1 4.6e-07 29.4 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat FlxA PF14282.1 KFP02880.1 - 0.00013 21.8 21.8 0.00013 21.8 15.1 9.1 4 3 5 9 9 9 1 FlxA-like protein AAA_27 PF13514.1 KFP02880.1 - 0.79 7.3 84.4 0.0028 15.4 34.8 2.6 1 1 2 3 3 3 0 AAA domain Surfac_D-trimer PF09006.6 KFP02880.1 - 2.8 7.7 10.4 2.1 8.1 3.7 3.4 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation C1q PF00386.16 KFP02881.1 - 1.9e-32 111.9 3.7 2.4e-32 111.6 2.6 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP02881.1 - 1.2e-11 43.9 50.7 2.4e-10 39.8 22.5 2.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CoA_transf_3 PF02515.12 KFP02882.1 - 8.1e-43 145.8 0.0 1e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF3643 PF12356.3 KFP02882.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3643) MFS_2 PF13347.1 KFP02883.1 - 1.6e-16 59.7 14.3 2e-15 56.1 9.9 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein 7tm_1 PF00001.16 KFP02884.1 - 9.4e-52 175.6 18.8 1.2e-51 175.3 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FIST PF08495.5 KFP02884.1 - 0.1 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 FIST N domain DUF4450 PF14614.1 KFP02884.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) ADAM_spacer1 PF05986.9 KFP02885.1 - 5e-34 116.5 0.1 1.6e-33 114.9 0.0 1.9 2 0 0 2 2 2 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFP02885.1 - 2.3e-33 114.0 130.4 2.9e-09 36.8 4.4 11.2 11 1 0 11 11 11 8 Thrombospondin type 1 domain Reprolysin PF01421.14 KFP02885.1 - 1.9e-30 105.9 0.0 3.5e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFP02885.1 - 4.2e-23 81.5 0.2 9.3e-23 80.4 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 KFP02885.1 - 4.4e-15 56.1 0.0 1.5e-14 54.3 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFP02885.1 - 8.5e-10 39.2 0.0 2.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP02885.1 - 1e-09 38.6 0.0 2.4e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP02885.1 - 7e-08 32.2 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFP02885.1 - 0.06 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Matrixin tRNA-synt_2b PF00587.20 KFP02886.1 - 9.3e-47 158.8 0.3 1.9e-46 157.8 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFP02886.1 - 4.9e-20 71.2 0.1 1.2e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KFP02886.1 - 2.3e-18 65.7 0.0 2e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 KFP02886.1 - 1.7e-12 47.0 0.1 3.9e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GSDH PF07995.6 KFP02887.1 - 2.2e-39 135.4 0.0 2.7e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.9 KFP02887.1 - 8.4e-07 28.7 0.9 1.5e-06 27.9 0.6 1.3 1 0 0 1 1 1 1 Folate receptor family p450 PF00067.17 KFP02888.1 - 8.8e-90 301.4 0.6 1.1e-89 301.0 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_10 PF12846.2 KFP02888.1 - 0.085 12.2 0.2 0.19 11.1 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain Remorin_C PF03763.8 KFP02888.1 - 0.45 10.0 5.1 0.14 11.6 1.4 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region PIP49_C PF12260.3 KFP02889.1 - 6.4e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Nodulin_late PF07127.6 KFP02889.1 - 0.9 9.7 3.7 1 9.5 0.9 2.1 2 0 0 2 2 2 0 Late nodulin protein HELP PF03451.9 KFP02890.1 - 4.1e-38 128.7 0.3 7.5e-38 127.9 0.2 1.4 1 0 0 1 1 1 1 HELP motif WD40 PF00400.27 KFP02890.1 - 1.3e-26 91.4 37.9 7e-05 22.5 0.2 10.6 11 0 0 11 11 11 6 WD domain, G-beta repeat Macoilin PF09726.4 KFP02890.1 - 0.35 9.1 2.9 0.51 8.5 2.0 1.2 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 KFP02890.1 - 0.5 10.7 4.0 0.41 11.0 1.7 1.7 2 0 0 2 2 2 0 SlyX Matrilin_ccoil PF10393.4 KFP02890.1 - 1.1 8.6 3.1 2.4 7.5 0.4 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin FA_desaturase PF00487.19 KFP02891.1 - 2e-23 83.1 15.3 5.1e-23 81.8 10.6 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KFP02891.1 - 7.8e-05 21.8 0.3 0.00027 20.1 0.1 2.0 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) zf-C2H2 PF00096.21 KFP02892.1 - 4.4e-19 67.6 22.9 2.4e-05 24.3 0.3 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP02892.1 - 1.3e-18 66.2 23.1 3e-08 33.5 0.1 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP02892.1 - 4.2e-14 51.7 17.6 0.00012 22.1 0.1 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger Transpos_assoc PF13963.1 KFP02892.1 - 0.0022 17.9 6.4 0.029 14.3 0.1 2.8 3 0 0 3 3 3 2 Transposase-associated domain zf-RING_3 PF14369.1 KFP02892.1 - 0.0055 16.6 2.8 0.5 10.4 0.0 3.3 3 0 0 3 3 3 1 zinc-finger zf-C2H2_jaz PF12171.3 KFP02892.1 - 0.0056 16.7 13.5 2.1 8.6 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KFP02892.1 - 0.0059 16.9 11.7 2 8.8 0.1 3.3 1 1 2 3 3 3 2 TRAF-type zinc finger CCAP PF11105.3 KFP02892.1 - 0.012 15.3 4.2 0.38 10.4 0.6 2.4 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Raffinose_syn PF05691.7 KFP02892.1 - 0.024 12.1 0.0 0.029 11.9 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 CHORD PF04968.7 KFP02892.1 - 0.045 13.9 10.7 7.6 6.8 1.4 3.5 1 1 3 4 4 4 0 CHORD IBR PF01485.16 KFP02892.1 - 0.046 13.5 0.8 0.046 13.5 0.6 2.8 1 1 1 3 3 3 0 IBR domain XPA_N PF01286.13 KFP02892.1 - 0.1 12.3 2.4 0.29 10.8 0.0 2.8 3 0 0 3 3 3 0 XPA protein N-terminal zf-CGNR PF11706.3 KFP02892.1 - 0.17 11.3 7.1 2.6 7.6 0.1 3.3 3 1 0 3 3 3 0 CGNR zinc finger zf-met PF12874.2 KFP02892.1 - 0.21 11.8 6.0 2.3 8.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP02892.1 - 1.4 8.8 0.1 1.4 8.8 0.0 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger Mito_carr PF00153.22 KFP02893.1 - 4.7e-67 221.7 2.2 9.1e-24 82.9 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 KFP02894.1 - 6.6e-73 240.5 1.4 1.4e-25 88.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PLDc_N PF13396.1 KFP02894.1 - 0.18 11.4 0.7 0.54 9.9 0.5 1.8 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal tRNA-synt_1b PF00579.20 KFP02895.1 - 2.3e-25 89.3 0.0 4.3e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.15 KFP02895.1 - 1.4e-21 75.9 0.2 3.1e-21 74.7 0.2 1.6 1 0 0 1 1 1 1 WHEP-TRS domain SbcD_C PF12320.3 KFP02895.1 - 0.11 12.5 0.1 25 4.9 0.0 2.7 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain WD40 PF00400.27 KFP02896.1 - 1e-28 98.1 14.3 2.1e-08 33.7 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFP02896.1 - 2.1e-10 40.6 0.0 4.9e-05 23.1 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFP02896.1 - 0.0075 14.4 0.1 0.049 11.7 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Pilt PF15453.1 KFP02897.1 - 1.1e-07 31.8 16.3 1.1e-07 31.8 11.3 2.9 2 1 0 2 2 2 1 Protein incorporated later into Tight Junctions V_ATPase_I PF01496.14 KFP02897.1 - 0.061 11.1 4.1 0.099 10.4 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Homeobox PF00046.24 KFP02897.1 - 0.064 12.8 0.9 0.2 11.2 0.6 1.9 1 0 0 1 1 1 0 Homeobox domain IncA PF04156.9 KFP02897.1 - 0.095 12.2 15.8 0.09 12.3 9.6 1.9 1 1 1 2 2 2 0 IncA protein DUF342 PF03961.8 KFP02897.1 - 0.38 9.1 6.7 0.66 8.3 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ApoO PF09769.4 KFP02897.1 - 0.38 10.4 3.8 0.27 10.9 0.3 2.5 2 0 0 2 2 2 0 Apolipoprotein O DUF1664 PF07889.7 KFP02897.1 - 1.4 8.7 5.8 1 9.1 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 KFP02898.1 - 5.6e-53 175.0 27.2 5.4e-12 45.1 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KFP02898.1 - 1.1e-06 28.4 0.1 0.0028 17.3 0.0 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFP02898.1 - 0.0015 16.7 9.4 0.43 8.6 4.1 4.0 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFP02898.1 - 0.011 14.1 0.0 0.024 12.9 0.0 1.6 1 1 0 1 1 1 0 Cytochrome D1 heme domain Env-gp36 PF09590.5 KFP02898.1 - 0.044 12.0 0.1 0.051 11.7 0.1 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein zf-C3HC4_4 PF15227.1 KFP02899.1 - 5.2e-14 51.8 1.0 7.5e-14 51.3 0.7 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFP02899.1 - 1.1e-10 40.9 0.2 1.5e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP02899.1 - 1.4e-09 37.8 1.4 1.9e-09 37.4 1.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP02899.1 - 3.1e-07 30.1 0.9 4.1e-07 29.7 0.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KFP02899.1 - 1.2e-06 28.1 0.1 1.5e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFP02899.1 - 5.4e-06 25.9 0.4 7.1e-06 25.6 0.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP02899.1 - 0.001 18.7 2.6 0.0017 18.0 1.8 1.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFP02899.1 - 0.0014 18.3 1.0 0.0017 18.1 0.7 1.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 KFP02899.1 - 0.0078 15.7 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.6 KFP02899.1 - 0.025 14.3 0.4 0.032 13.9 0.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 KFP02899.1 - 0.23 11.5 5.1 1.7 8.8 3.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Fer2 PF00111.22 KFP02899.1 - 0.73 9.6 4.8 0.2 11.4 0.8 1.9 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain PRY PF13765.1 KFP02900.1 - 3.1e-20 71.4 0.2 5.3e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFP02900.1 - 1.4e-15 57.4 0.0 1.7e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 SPRY domain SPRY PF00622.23 KFP02901.1 - 5.3e-21 74.9 0.0 7e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFP02901.1 - 5.5e-20 70.6 0.1 1.3e-19 69.4 0.1 1.6 2 0 0 2 2 2 1 SPRY-associated domain Activin_recp PF01064.18 KFP02902.1 - 0.035 14.7 11.1 0.05 14.2 7.7 1.2 1 0 0 1 1 1 0 Activin types I and II receptor domain UPAR_LY6 PF00021.16 KFP02902.1 - 0.16 12.4 11.8 0.36 11.2 8.2 1.7 1 1 0 1 1 1 0 u-PAR/Ly-6 domain SPRY PF00622.23 KFP02903.1 - 2e-25 89.2 0.4 2.4e-25 89.0 0.2 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFP02903.1 - 3.9e-18 64.7 0.1 6.6e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 SPRY-associated domain FYRN PF05964.9 KFP02903.1 - 0.14 11.6 0.1 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 F/Y-rich N-terminus Amino_oxidase PF01593.19 KFP02904.1 - 3.9e-71 240.4 0.2 1.4e-69 235.3 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFP02904.1 - 3.4e-16 59.0 0.7 1.2e-15 57.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFP02904.1 - 4.5e-09 35.6 0.2 2.6e-07 29.8 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFP02904.1 - 3.8e-07 30.3 0.5 8.4e-07 29.3 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFP02904.1 - 8.5e-07 28.3 0.1 1.4e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 KFP02904.1 - 2.1e-06 27.4 0.1 5.1e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KFP02904.1 - 3.2e-06 27.3 0.1 4.4e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFP02904.1 - 5.2e-06 25.5 0.1 8.7e-06 24.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KFP02904.1 - 6e-06 25.5 0.4 1.7e-05 24.0 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFP02904.1 - 1.1e-05 25.3 0.0 4.5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFP02904.1 - 3.4e-05 22.5 0.3 5.5e-05 21.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KFP02904.1 - 0.00061 18.9 0.0 0.00091 18.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 KFP02904.1 - 0.0023 17.3 1.6 0.013 14.9 0.3 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FMO-like PF00743.14 KFP02904.1 - 0.0095 14.1 0.0 0.015 13.4 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KFP02904.1 - 0.01 15.5 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KFP02904.1 - 0.013 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFP02904.1 - 0.014 15.5 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 KFP02904.1 - 0.022 13.4 0.4 0.033 12.8 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF2207 PF09972.4 KFP02904.1 - 0.024 13.2 2.2 0.031 12.8 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NAD_Gly3P_dh_N PF01210.18 KFP02904.1 - 0.027 14.1 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 KFP02904.1 - 0.03 13.1 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.13 KFP02904.1 - 0.075 13.0 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KFP02904.1 - 0.2 11.7 0.1 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KFP02904.1 - 0.22 11.5 1.3 0.37 10.7 0.6 1.6 2 0 0 2 2 1 0 NADH(P)-binding zf-C2H2 PF00096.21 KFP02905.1 - 9.5e-44 145.1 54.3 3.1e-06 27.1 0.2 9.1 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP02905.1 - 3.2e-42 140.7 69.6 1.1e-08 34.9 0.4 9.8 9 1 0 9 9 9 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP02905.1 - 5.3e-24 82.7 55.8 0.00095 19.3 0.5 8.8 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP02905.1 - 6.2e-11 41.8 49.8 0.0015 18.3 0.0 10.0 9 4 0 9 9 9 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFP02905.1 - 0.00013 21.8 42.6 0.28 11.1 3.0 8.3 4 3 2 6 6 6 4 Zinc ribbon domain zf-trcl PF13451.1 KFP02905.1 - 0.00054 19.5 35.1 0.89 9.2 0.6 8.0 5 3 1 6 6 6 3 Probable zinc-binding domain XPA_N PF01286.13 KFP02905.1 - 0.0011 18.5 33.5 1.8 8.3 0.1 8.6 8 1 1 9 9 9 3 XPA protein N-terminal zf-C2H2_jaz PF12171.3 KFP02905.1 - 0.015 15.4 31.7 0.9 9.7 0.1 8.2 7 1 2 9 9 9 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_2 PF13240.1 KFP02905.1 - 0.046 13.2 0.4 0.046 13.2 0.3 7.6 7 2 0 7 7 7 0 zinc-ribbon domain zf-LYAR PF08790.6 KFP02905.1 - 0.096 12.4 20.9 2.5 7.8 0.0 7.7 9 0 0 9 9 9 0 LYAR-type C2HC zinc finger FYDLN_acid PF09538.5 KFP02905.1 - 0.15 12.6 15.8 9.7 6.8 1.9 6.0 3 2 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_recom PF13408.1 KFP02905.1 - 0.38 11.0 29.0 1.8 8.8 1.1 6.2 4 2 2 6 6 6 0 Recombinase zinc beta ribbon domain BolA PF01722.13 KFP02905.1 - 0.38 10.7 8.7 26 4.8 0.0 4.7 4 1 1 5 5 5 0 BolA-like protein HypA PF01155.14 KFP02905.1 - 0.45 10.2 26.8 0.74 9.5 0.4 4.9 2 1 2 5 5 5 0 Hydrogenase expression/synthesis hypA family DUF2321 PF10083.4 KFP02905.1 - 0.5 9.8 26.5 1.1 8.7 0.1 6.3 1 1 4 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF2180 PF09947.4 KFP02905.1 - 2 8.2 7.9 1.8 8.3 1.3 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) C1_4 PF07975.7 KFP02905.1 - 3.7 7.6 24.4 7.8 6.5 0.4 5.9 3 3 3 6 6 6 0 TFIIH C1-like domain zf-C2H2 PF00096.21 KFP02906.1 - 1.5e-12 47.0 5.9 2.3e-06 27.5 0.3 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP02906.1 - 7.2e-09 35.5 0.9 7.2e-09 35.5 0.6 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP02906.1 - 1.1e-05 25.3 8.7 0.0039 17.4 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2256 PF10013.4 KFP02906.1 - 0.00021 20.9 0.5 0.026 14.2 0.2 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-trcl PF13451.1 KFP02906.1 - 0.021 14.4 0.2 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Probable zinc-binding domain DUF2321 PF10083.4 KFP02906.1 - 0.041 13.3 0.5 0.4 10.1 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_6 PF13912.1 KFP02906.1 - 0.13 12.2 3.2 0.38 10.7 0.6 2.5 2 2 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 KFP02906.1 - 0.14 11.8 2.0 1.1 9.0 1.5 2.0 1 1 1 2 2 2 0 BED zinc finger SPRY PF00622.23 KFP02907.1 - 3.3e-27 95.0 0.3 4.3e-27 94.6 0.2 1.2 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFP02907.1 - 1.3e-21 75.7 0.2 2.2e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 SPRY-associated domain MAS20 PF02064.10 KFP02909.1 - 1.1e-55 186.7 0.0 1.3e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor TPR_11 PF13414.1 KFP02909.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 TPR repeat DUF221 PF02714.10 KFP02909.1 - 0.042 12.7 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 TPR_1 PF00515.23 KFP02909.1 - 0.069 12.7 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFP02909.1 - 0.072 13.7 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SicP-binding PF09119.5 KFP02909.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 SicP binding RRM_1 PF00076.17 KFP02910.1 - 7.4e-30 102.3 0.8 5e-16 58.0 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP02910.1 - 2e-21 75.7 0.5 1.3e-13 50.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP02910.1 - 1.3e-08 34.4 2.0 3.3e-05 23.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KFP02910.1 - 0.00096 18.8 0.1 1.5 8.5 0.1 2.6 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KFP02910.1 - 0.0026 17.5 0.0 0.2 11.4 0.0 2.7 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Cellulose_synt PF03552.9 KFP02910.1 - 0.14 10.4 7.9 0.2 9.8 5.4 1.2 1 0 0 1 1 1 0 Cellulose synthase RBB1NT PF08169.6 KFP02911.1 - 1.1e-38 131.0 1.7 1.1e-38 131.0 1.2 2.6 2 0 0 2 2 2 1 RBB1NT (NUC162) domain ARID PF01388.16 KFP02911.1 - 4.7e-25 87.2 0.0 1.5e-24 85.6 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.3 KFP02911.1 - 5.2e-12 45.2 0.7 5.2e-12 45.2 0.5 3.0 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain PWWP PF00855.12 KFP02911.1 - 0.033 14.3 0.2 0.033 14.3 0.1 4.5 4 0 0 4 4 4 0 PWWP domain polyprenyl_synt PF00348.12 KFP02912.1 - 8.6e-50 169.0 0.0 1e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase LRR_4 PF12799.2 KFP02913.1 - 3.7e-17 61.5 28.5 3.8e-06 26.3 3.4 5.3 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 KFP02913.1 - 1.1e-14 53.8 0.2 2.1e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 KFP02913.1 - 1.2e-11 44.1 19.2 2.6e-06 27.0 2.8 4.2 3 1 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KFP02913.1 - 1.2e-08 34.7 0.2 2.7e-08 33.5 0.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KFP02913.1 - 4.5e-07 29.2 15.5 3.6 7.9 0.8 7.6 7 0 0 7 7 7 2 Leucine Rich repeat Ubiquitin_2 PF14560.1 KFP02913.1 - 9.1e-07 29.0 0.1 3.7e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain LRR_7 PF13504.1 KFP02913.1 - 3.9e-05 23.1 7.1 20 5.9 0.4 7.2 7 0 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 KFP02913.1 - 0.00032 20.3 19.1 3.5 8.0 0.0 7.3 4 3 2 6 6 6 2 Leucine Rich Repeat Galactosyl_T PF01762.16 KFP02914.1 - 3.5e-29 101.8 0.0 1.8e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase G-gamma PF00631.17 KFP02915.1 - 4.3e-17 61.6 0.0 4.9e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 GGL domain G2F PF07474.7 KFP02916.1 - 7.6e-80 266.8 0.8 1.2e-79 266.1 0.5 1.3 1 0 0 1 1 1 1 G2F domain Ldl_recept_b PF00058.12 KFP02916.1 - 1.2e-39 134.3 2.9 9.3e-12 45.0 0.0 4.9 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B EGF_3 PF12947.2 KFP02916.1 - 2.5e-32 110.5 102.4 2.5e-09 36.9 6.9 6.6 6 0 0 6 6 6 6 EGF domain NIDO PF06119.9 KFP02916.1 - 1.2e-22 80.4 0.4 3.4e-22 78.9 0.3 1.9 1 0 0 1 1 1 1 Nidogen-like EGF_CA PF07645.10 KFP02916.1 - 2e-20 72.4 90.2 6.4e-09 35.6 4.8 6.8 6 0 0 6 6 5 5 Calcium-binding EGF domain cEGF PF12662.2 KFP02916.1 - 5.4e-20 70.7 53.6 2.1e-07 30.4 0.8 6.8 6 0 0 6 6 6 5 Complement Clr-like EGF-like Thyroglobulin_1 PF00086.13 KFP02916.1 - 1.6e-16 59.3 2.5 8.8e-16 57.0 1.7 2.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat FXa_inhibition PF14670.1 KFP02916.1 - 6.1e-16 58.2 95.1 2e-08 34.2 4.9 6.6 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KFP02916.1 - 2.5e-07 30.5 99.1 0.0047 16.8 4.4 7.6 7 0 0 7 7 7 6 EGF-like domain SGL PF08450.7 KFP02916.1 - 2.1e-05 24.0 0.1 8.9e-05 21.9 0.0 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region EGF_MSP1_1 PF12946.2 KFP02916.1 - 0.2 11.4 64.0 0.12 12.2 0.8 5.9 6 0 0 6 6 5 0 MSP1 EGF domain 1 hEGF PF12661.2 KFP02916.1 - 0.35 11.0 28.6 0.18 11.9 0.3 7.0 6 0 0 6 6 6 0 Human growth factor-like EGF PspB PF06667.7 KFP02917.1 - 0.03 14.2 3.0 0.081 12.8 2.1 1.8 1 0 0 1 1 1 0 Phage shock protein B ERO1 PF04137.10 KFP02918.1 - 2.6e-133 444.4 0.0 2.9e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Death PF00531.17 KFP02919.1 - 2.3e-11 43.3 0.1 3.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Death domain Gal-bind_lectin PF00337.17 KFP02920.1 - 2.9e-75 249.9 0.0 2.5e-38 130.4 0.0 2.1 2 0 0 2 2 2 2 Galactoside-binding lectin WIF PF02019.13 KFP02920.1 - 0.013 14.8 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 WIF domain tRNA_anti-codon PF01336.20 KFP02920.1 - 0.12 12.2 0.7 2 8.3 0.0 3.0 4 0 0 4 4 4 0 OB-fold nucleic acid binding domain Spectrin PF00435.16 KFP02921.1 - 3.4e-74 245.8 33.8 1e-24 86.8 6.0 4.4 4 0 0 4 4 4 4 Spectrin repeat CH PF00307.26 KFP02921.1 - 3.1e-42 143.0 0.2 6.7e-23 80.8 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KFP02921.1 - 7e-27 93.2 0.0 3.7e-26 90.8 0.0 2.4 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KFP02921.1 - 5.2e-13 48.4 0.1 3.9e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.27 KFP02921.1 - 7.6e-09 34.2 0.9 0.0025 16.9 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFP02921.1 - 1.8e-07 30.6 0.5 7.5e-07 28.6 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP02921.1 - 1.5e-05 24.4 1.5 0.033 14.0 0.3 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KFP02921.1 - 3.2e-05 23.9 0.6 0.00012 22.1 0.4 2.1 1 0 0 1 1 1 1 EF-hand domain pair XisI PF08869.6 KFP02921.1 - 3.5 7.7 9.4 0.096 12.8 0.5 2.7 3 0 0 3 3 3 0 XisI protein S-methyl_trans PF02574.11 KFP02922.1 - 2.6e-101 338.9 0.0 5.2e-101 337.9 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 KFP02922.1 - 7.3e-83 276.9 0.0 1.2e-82 276.2 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 KFP02922.1 - 5.4e-43 146.8 0.4 1.7e-41 141.9 0.0 2.7 3 0 0 3 3 3 1 Pterin binding enzyme B12-binding_2 PF02607.12 KFP02922.1 - 1.7e-20 72.8 0.1 7e-20 70.8 0.0 2.2 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.14 KFP02922.1 - 1.8e-17 63.3 0.1 5.1e-17 61.8 0.1 1.8 1 0 0 1 1 1 1 B12 binding domain CdhD PF03599.11 KFP02922.1 - 0.0042 15.6 0.1 0.0075 14.8 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit IPT PF01745.11 KFP02922.1 - 0.06 12.5 0.1 0.17 11.0 0.0 1.8 1 0 0 1 1 1 0 Isopentenyl transferase PMP22_Claudin PF00822.15 KFP02923.1 - 1.1e-09 38.1 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP02923.1 - 2.2e-07 30.7 0.0 2.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction MoaC PF01967.16 KFP02924.1 - 3.5e-28 97.9 0.0 6.3e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KFP02925.1 - 3.6e-41 139.8 0.0 5.3e-41 139.2 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KFP02925.1 - 2.4e-29 102.6 0.1 4.1e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KFP02925.1 - 6.6e-10 39.2 0.0 1.5e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KFP02925.1 - 2.9e-08 33.7 0.1 1.1e-07 31.8 0.0 2.0 3 0 0 3 3 3 1 4Fe-4S single cluster domain Lipoprotein_9 PF03180.9 KFP02925.1 - 0.093 11.6 0.1 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 NLPA lipoprotein LRR_8 PF13855.1 KFP02926.1 - 1.7e-28 98.1 18.4 8.7e-13 47.8 2.7 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP02926.1 - 3.7e-19 67.9 20.9 1.6e-06 27.5 2.8 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) I-set PF07679.11 KFP02926.1 - 5.8e-15 54.9 0.0 1.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_5 PF13306.1 KFP02926.1 - 4.6e-13 48.9 0.1 6.4e-11 42.0 0.0 2.1 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP02926.1 - 6e-12 43.8 23.7 0.043 13.8 0.5 8.1 8 0 0 8 8 7 4 Leucine Rich Repeat fn3 PF00041.16 KFP02926.1 - 7.3e-08 32.4 0.1 3.8e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Ig_3 PF13927.1 KFP02926.1 - 1.2e-07 32.0 0.1 8.5e-07 29.3 0.0 2.5 1 1 1 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFP02926.1 - 4.5e-06 26.6 0.0 1.4e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP02926.1 - 2.7e-05 24.2 0.0 7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.1 KFP02926.1 - 0.00012 21.6 4.2 0.0031 17.0 0.6 2.3 1 1 1 2 2 2 2 Leucine-rich repeat V-set PF07686.12 KFP02926.1 - 0.0065 16.3 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Immunoglobulin V-set domain LRR_7 PF13504.1 KFP02926.1 - 0.17 12.2 23.5 2.2 8.8 0.1 7.2 8 0 0 8 8 6 0 Leucine rich repeat Bromo_TP PF07524.8 KFP02927.1 - 7.3e-22 76.8 0.2 1.8e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated Dicer_dimer PF03368.9 KFP02928.1 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.20 KFP02928.1 - 0.022 15.3 0.0 0.078 13.5 0.0 2.1 1 0 0 1 1 1 0 Double-stranded RNA binding motif PfkB PF00294.19 KFP02931.1 - 4.6e-56 190.1 0.1 5.7e-56 189.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFP02931.1 - 2.8e-06 26.7 0.0 4.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CoA_binding_2 PF13380.1 KFP02931.1 - 0.0088 16.2 0.0 0.041 14.0 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain BRE PF06113.7 KFP02932.1 - 5.7e-227 752.0 0.1 6.4e-227 751.8 0.1 1.0 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) UQ_con PF00179.21 KFP02932.1 - 0.0028 17.0 3.5 0.69 9.3 0.1 2.7 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme bZIP_1 PF00170.16 KFP02933.1 - 2e-09 37.2 20.0 3.1e-09 36.6 13.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP02933.1 - 1.2e-06 28.1 19.1 2.1e-06 27.4 13.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFP02933.1 - 2.4e-05 24.5 14.1 4.1e-05 23.7 9.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor HAUS6_N PF14661.1 KFP02933.1 - 0.018 14.4 1.9 0.023 14.0 1.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 KFP02933.1 - 0.19 9.5 1.7 0.23 9.2 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFP02933.1 - 0.82 9.2 6.5 1.3 8.5 4.5 1.3 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 KFP02933.1 - 1 7.6 4.3 1.4 7.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2681 PF10883.3 KFP02933.1 - 1.3 9.2 6.3 2.6 8.3 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) APG6 PF04111.7 KFP02933.1 - 1.6 7.7 8.2 2.2 7.2 5.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_G5 PF04599.7 KFP02933.1 - 4.8 5.7 6.4 6.9 5.2 4.4 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Lipase_GDSL PF00657.17 KFP02934.1 - 5.7e-88 294.6 0.0 1.5e-29 103.4 0.0 3.2 3 0 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFP02934.1 - 2e-26 93.2 0.1 9.8e-09 35.5 0.1 4.8 3 2 0 3 3 3 3 GDSL-like Lipase/Acylhydrolase family Metallophos PF00149.23 KFP02935.1 - 5.4e-44 150.0 0.2 6.5e-44 149.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 KFP02937.1 - 1.1e-43 143.1 10.0 2.9e-10 38.6 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFP02937.1 - 6.9e-39 131.8 3.7 1.1e-21 76.7 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP02937.1 - 4.6e-36 122.2 10.0 3.7e-17 61.6 0.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFP02937.1 - 9e-32 106.0 5.4 9.7e-10 37.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFP02937.1 - 2e-28 96.4 5.4 5.6e-07 28.6 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFP02937.1 - 6.6e-15 54.7 0.1 1.8e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFP02937.1 - 1.3e-09 37.7 0.5 3.5e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFP02937.1 - 1.5e-08 34.6 0.0 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KFP02937.1 - 1e-06 28.2 0.0 0.17 11.5 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KFP02937.1 - 1.3e-06 28.2 0.5 6.5e-06 26.0 0.1 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 KFP02937.1 - 0.00061 19.2 1.6 0.00072 19.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 KFP02937.1 - 0.001 18.8 0.5 0.17 11.6 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 KFP02937.1 - 0.0043 16.6 0.1 0.12 11.9 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 KFP02937.1 - 0.013 15.4 1.7 1.8 8.6 0.1 2.4 3 0 0 3 3 2 0 RNA polymerase Rpb4 Poly_export PF02563.11 KFP02937.1 - 0.04 13.6 0.1 2.6 7.8 0.0 2.9 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein DUF3349 PF11829.3 KFP02937.1 - 0.059 13.8 0.4 11 6.4 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) MotA_activ PF09114.5 KFP02937.1 - 0.059 13.1 0.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 KFP02937.1 - 0.064 12.8 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 KFP02937.1 - 0.083 12.4 0.1 0.51 9.8 0.0 1.9 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF1880 PF08976.6 KFP02937.1 - 0.1 12.7 0.0 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) CMD PF02627.15 KFP02937.1 - 0.13 12.1 0.2 4 7.3 0.0 2.5 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family VCBS PF13517.1 KFP02937.1 - 6.4 7.2 7.5 81 3.6 0.8 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TPR_11 PF13414.1 KFP02938.1 - 2.8e-26 90.9 16.2 1.5e-07 30.9 0.2 7.6 5 2 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 KFP02938.1 - 3.6e-25 85.8 20.2 2.9e-05 23.6 0.1 10.7 12 0 0 12 12 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFP02938.1 - 4.1e-21 75.0 13.2 3.9e-07 30.5 0.2 7.2 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFP02938.1 - 8.1e-20 69.5 12.1 3e-05 23.4 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP02938.1 - 2.2e-18 64.8 5.8 0.0029 17.6 0.0 7.9 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFP02938.1 - 2.2e-16 59.5 25.7 1.4e-07 31.3 0.1 7.7 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFP02938.1 - 4.3e-16 57.9 22.2 0.025 15.1 0.0 11.1 6 3 6 12 12 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFP02938.1 - 1.8e-10 39.8 16.0 0.032 13.9 0.0 8.9 11 1 1 12 12 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP02938.1 - 3.6e-10 40.0 21.8 0.0015 18.7 0.1 7.7 5 2 3 8 8 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KFP02938.1 - 7.5e-08 32.3 13.7 0.046 13.8 2.1 6.1 4 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFP02938.1 - 1.3e-07 31.3 15.2 0.035 13.9 2.5 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFP02938.1 - 1.3e-07 30.8 12.2 0.048 13.4 0.0 8.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFP02938.1 - 1.7e-07 30.9 16.1 0.15 12.0 0.0 6.9 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFP02938.1 - 4.7e-07 29.8 18.8 0.089 13.2 0.1 9.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_20 PF14561.1 KFP02938.1 - 2.9e-06 27.3 9.3 0.013 15.5 0.9 4.9 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFP02938.1 - 5.4e-05 22.3 9.9 0.0008 18.5 0.4 4.6 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.4 KFP02938.1 - 5.8e-05 21.8 2.5 0.00034 19.3 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_3 PF07720.7 KFP02938.1 - 0.0011 18.6 0.7 15 5.5 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KFP02938.1 - 0.005 16.6 3.7 2.1 8.2 0.0 5.4 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 KFP02938.1 - 0.015 14.0 4.3 6.6 5.3 0.7 3.4 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 KFP02938.1 - 0.019 15.3 7.2 6.8 7.4 0.1 5.1 4 0 0 4 4 3 0 Tetratricopeptide repeat EF-hand_7 PF13499.1 KFP02939.1 - 3.6e-11 43.0 2.5 5e-11 42.5 1.6 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP02939.1 - 2.5e-08 33.1 0.3 0.0054 16.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFP02939.1 - 5e-07 28.5 0.2 0.00062 18.8 0.1 2.7 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFP02939.1 - 0.0023 17.4 0.5 0.024 14.2 0.1 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP02939.1 - 0.0047 16.2 3.1 0.013 14.8 0.6 2.6 2 1 0 2 2 2 1 EF hand Cript PF10235.4 KFP02940.1 - 2.1e-22 79.2 1.2 2.1e-22 79.2 0.8 1.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 KFP02940.1 - 0.33 10.8 8.0 1.4 8.7 5.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon Cas_CXXC_CXXC PF09706.5 KFP02940.1 - 0.41 10.8 0.2 0.41 10.8 0.1 2.6 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-BED PF02892.10 KFP02940.1 - 0.62 9.8 5.4 0.94 9.2 0.5 2.4 2 0 0 2 2 2 0 BED zinc finger zf-ribbon_3 PF13248.1 KFP02940.1 - 4.6 6.5 6.8 2.3 7.5 1.2 2.3 2 1 0 2 2 2 0 zinc-ribbon domain PIG-F PF06699.6 KFP02941.1 - 2.3e-50 171.2 15.4 2.8e-50 170.9 10.7 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F E1-E2_ATPase PF00122.15 KFP02941.1 - 0.18 10.7 0.4 0.26 10.2 0.3 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Ras PF00071.17 KFP02942.1 - 9.3e-42 142.1 0.0 1.1e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP02942.1 - 4.5e-10 40.0 0.0 7.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP02942.1 - 0.0082 15.3 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP02942.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain TMEM247 PF15444.1 KFP02943.1 - 3.3e-07 30.3 0.3 3.3e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 247 PAS_11 PF14598.1 KFP02944.1 - 4.2e-27 94.2 0.2 8.1e-23 80.5 0.1 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 KFP02944.1 - 2e-25 88.6 0.0 1.6e-19 69.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold HIF-1a_CTAD PF08778.5 KFP02944.1 - 8.8e-21 73.0 0.4 2.2e-20 71.8 0.3 1.7 1 0 0 1 1 1 1 HIF-1 alpha C terminal transactivation domain HIF-1 PF11413.3 KFP02944.1 - 7.5e-19 66.6 0.8 9.7e-18 63.0 0.6 2.5 2 0 0 2 2 2 1 Hypoxia-inducible factor-1 PAS PF00989.19 KFP02944.1 - 4.4e-14 52.2 0.6 2.5e-06 27.2 0.0 2.6 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.1 KFP02944.1 - 4.9e-11 42.9 0.0 1.2e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFP02944.1 - 3.5e-07 30.2 0.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFP02944.1 - 0.083 12.5 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 KFP02945.1 - 3.2e-67 226.3 0.0 5.5e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02945.1 - 2e-37 128.6 0.0 3.4e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFP02945.1 - 2.8e-31 106.9 24.0 6.8e-16 57.7 3.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFP02945.1 - 8.7e-10 38.9 0.2 8.7e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFP02945.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP02945.1 - 0.0023 17.0 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP02945.1 - 0.073 12.7 0.0 0.27 10.9 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FYVE_2 PF02318.11 KFP02945.1 - 3 7.7 15.7 3.5 7.5 2.9 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.2 KFP02945.1 - 6.2 6.7 14.8 0.11 12.3 2.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon C2 PF00168.25 KFP02946.1 - 4.1e-12 45.7 0.0 5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 C2 domain DUF4114 PF13448.1 KFP02946.1 - 0.12 13.1 0.2 0.16 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) Homeobox PF00046.24 KFP02947.1 - 1.3e-14 53.5 2.2 1.6e-14 53.2 0.3 1.9 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFP02947.1 - 1.9e-12 46.6 0.5 4.5e-12 45.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFP02947.1 - 0.0037 16.3 2.5 0.0043 16.0 0.2 2.3 2 1 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 KFP02947.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix Methyltransf_16 PF10294.4 KFP02949.1 - 2.5e-17 62.8 0.1 2.9e-17 62.6 0.1 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 KFP02949.1 - 0.00079 19.8 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.7 KFP02949.1 - 0.0032 16.5 0.1 0.0046 16.0 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Methyltransf_23 PF13489.1 KFP02949.1 - 0.0044 16.7 0.0 0.076 12.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP02949.1 - 0.01 16.3 0.1 0.021 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP02949.1 - 0.013 15.8 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KFP02949.1 - 0.021 14.3 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFP02949.1 - 0.035 14.7 0.1 0.054 14.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFP02949.1 - 0.053 12.8 0.3 0.097 12.0 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Peptidase_S9 PF00326.16 KFP02950.1 - 1.9e-35 122.0 0.0 3.7e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 KFP02950.1 - 1.2e-25 89.9 1.3 2.1e-25 89.2 0.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_6 PF12697.2 KFP02950.1 - 0.0009 19.1 0.0 0.0016 18.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP02950.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFP02950.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Myb_DNA-bind_5 PF13873.1 KFP02950.1 - 9 6.2 8.2 0.86 9.5 0.8 2.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Alpha-amylase PF00128.19 KFP02951.1 - 1.6e-71 241.3 2.0 2.4e-71 240.7 1.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KFP02951.1 - 0.026 14.6 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Glyco_hydro_70 PF02324.11 KFP02951.1 - 0.031 12.0 0.0 0.047 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Nup35_RRM_2 PF14605.1 KFP02951.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PP2C PF00481.16 KFP02952.1 - 3.4e-83 278.9 0.0 4.2e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.8 KFP02952.1 - 1.9e-35 120.8 0.1 3.6e-35 119.8 0.1 1.5 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.1 KFP02952.1 - 2.6e-07 30.2 0.0 5.5e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFP02952.1 - 0.0016 18.1 0.0 0.8 9.3 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PPR_2 PF13041.1 KFP02953.1 - 2.4e-39 133.0 17.7 5.1e-07 29.5 0.0 15.6 14 2 4 18 18 18 9 PPR repeat family PPR PF01535.15 KFP02953.1 - 6.1e-35 116.7 34.5 0.00075 19.3 0.0 18.4 19 0 0 19 19 19 7 PPR repeat PPR_3 PF13812.1 KFP02953.1 - 1.2e-31 106.3 13.9 0.047 13.9 0.0 16.6 17 0 0 17 17 16 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFP02953.1 - 3e-23 80.9 4.8 1.5e-05 24.3 0.0 9.7 10 1 1 11 11 11 6 PPR repeat TPR_14 PF13428.1 KFP02953.1 - 5.9e-10 38.8 2.1 13 6.7 0.0 9.9 11 1 1 12 12 11 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFP02953.1 - 4.2e-08 33.3 4.6 9.3 6.6 0.0 8.8 8 2 1 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFP02953.1 - 3.6e-06 27.4 0.0 4 8.2 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP02953.1 - 2.6e-05 24.2 8.0 4.8 7.4 0.0 6.8 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFP02953.1 - 0.0052 16.6 6.1 18 5.3 0.1 7.2 7 1 1 8 8 8 0 Tetratricopeptide repeat ATP13 PF12921.2 KFP02953.1 - 0.0064 15.8 0.2 13 5.1 0.0 4.8 4 1 0 4 4 4 0 Mitochondrial ATPase expression TPR_2 PF07719.12 KFP02953.1 - 0.016 15.0 0.5 74 3.6 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFP02953.1 - 0.023 14.4 7.7 11 6.1 0.0 6.5 9 0 0 9 9 8 0 Tetratricopeptide repeat ABC_tran PF00005.22 KFP02954.1 - 1.9e-29 102.7 0.0 3.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KFP02954.1 - 2.3e-20 72.6 7.7 4e-20 71.8 5.3 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_23 PF13476.1 KFP02954.1 - 1.3e-06 28.9 0.0 2.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KFP02954.1 - 1.7e-06 28.1 6.4 6.6e-06 26.3 1.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFP02954.1 - 3e-05 23.4 0.1 6.1e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KFP02954.1 - 4.5e-05 22.7 0.9 0.0028 16.9 0.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFP02954.1 - 0.00017 20.7 0.1 0.025 13.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 KFP02954.1 - 0.00035 20.6 0.0 0.00068 19.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KFP02954.1 - 0.0018 17.7 0.1 0.0085 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFP02954.1 - 0.0039 16.3 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KFP02954.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KFP02954.1 - 0.013 16.2 0.1 0.024 15.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFP02954.1 - 0.016 14.9 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 KFP02954.1 - 0.024 13.4 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 KFP02954.1 - 0.046 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KFP02954.1 - 0.048 13.9 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KFP02954.1 - 0.055 12.2 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 KFP02954.1 - 0.057 12.3 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 KFP02954.1 - 0.064 12.7 0.0 0.092 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 KFP02954.1 - 0.076 12.6 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 KFP02954.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KFP02954.1 - 0.12 12.4 0.3 0.42 10.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFP02954.1 - 0.19 11.5 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AzlD PF05437.7 KFP02954.1 - 0.61 10.0 6.3 0.14 12.1 1.5 2.1 2 0 0 2 2 1 0 Branched-chain amino acid transport protein (AzlD) DLIC PF05783.6 KFP02955.1 - 1.1e-09 37.4 0.2 1.1e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Arf PF00025.16 KFP02955.1 - 0.0031 16.7 0.0 0.0065 15.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP02955.1 - 0.0036 16.4 0.0 0.007 15.5 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFP02955.1 - 0.016 15.6 0.0 0.076 13.5 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein PH PF00169.24 KFP02956.1 - 2e-24 85.8 2.6 6.8e-18 64.7 0.0 3.7 3 0 0 3 3 3 2 PH domain MyTH4 PF00784.12 KFP02956.1 - 1.4e-19 70.1 0.6 1.4e-19 70.1 0.4 2.4 3 0 0 3 3 3 1 MyTH4 domain FERM_M PF00373.13 KFP02956.1 - 2.9e-12 46.8 0.0 2.9e-12 46.8 0.0 2.8 2 1 0 2 2 2 1 FERM central domain PH_11 PF15413.1 KFP02956.1 - 2.2e-07 31.1 2.2 2.2e-07 31.1 1.5 5.3 4 2 0 4 4 4 1 Pleckstrin homology domain PH_8 PF15409.1 KFP02956.1 - 6.5e-07 29.3 0.1 5e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain 3-HAO PF06052.7 KFP02959.1 - 6.9e-76 252.7 0.1 4.2e-74 246.9 0.3 2.0 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KFP02959.1 - 7.8e-13 47.7 0.0 4.1e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFP02959.1 - 2.3e-05 23.7 0.2 0.012 14.9 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KFP02959.1 - 0.00093 18.8 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 KFP02959.1 - 0.03 13.9 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Cupin Cupin_1 PF00190.17 KFP02959.1 - 0.034 13.5 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Cupin AraC_binding_2 PF14525.1 KFP02959.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.4 2 0 0 2 2 2 0 AraC-binding-like domain BAH PF01426.13 KFP02960.1 - 1.9e-28 98.6 0.9 1.9e-27 95.3 0.6 2.3 1 1 0 1 1 1 1 BAH domain ELM2 PF01448.19 KFP02960.1 - 2.2e-12 47.4 1.9 5.6e-12 46.1 0.0 2.6 2 1 0 2 2 2 1 ELM2 domain GATA PF00320.22 KFP02960.1 - 1.4e-08 33.8 9.0 3.5e-08 32.6 6.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.26 KFP02960.1 - 4.9e-05 23.3 0.1 0.00039 20.4 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Herpes_US12 PF05363.7 KFP02960.1 - 0.0096 16.4 0.4 0.07 13.6 0.0 2.4 2 0 0 2 2 2 1 Herpesvirus US12 family COX7a PF02238.10 KFP02961.1 - 2.4e-25 87.9 0.0 3.1e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa HELP PF03451.9 KFP02962.1 - 2e-37 126.5 0.2 3.9e-37 125.6 0.2 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.27 KFP02962.1 - 1.7e-26 91.0 23.0 5e-05 23.0 0.2 10.1 11 0 0 11 11 11 6 WD domain, G-beta repeat Ribosomal_S7 PF00177.16 KFP02962.1 - 0.019 14.5 0.6 0.034 13.7 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e CPSF_A PF03178.10 KFP02962.1 - 0.12 11.3 0.0 3.5 6.6 0.0 2.9 2 1 0 3 3 3 0 CPSF A subunit region SlyX PF04102.7 KFP02962.1 - 0.17 12.2 3.1 0.085 13.2 0.3 1.8 2 0 0 2 2 2 0 SlyX PIP49_C PF12260.3 KFP02964.1 - 7e-12 45.1 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DUF3844 PF12955.2 KFP02964.1 - 1.6 8.8 4.3 3.4 7.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3844) Yae1_N PF09811.4 KFP02965.1 - 1.6e-12 46.7 29.4 0.021 14.3 16.5 3.7 2 1 0 2 2 2 2 Essential protein Yae1, N terminal GLTSCR1 PF15249.1 KFP02967.1 - 1.3e-32 112.1 1.4 3.3e-32 110.8 0.9 1.8 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region Tetraspannin PF00335.15 KFP02969.1 - 2.1e-44 151.4 11.2 4.9e-44 150.2 7.8 1.5 1 1 0 1 1 1 1 Tetraspanin family ClpS PF02617.12 KFP02970.1 - 1.4e-20 72.7 0.3 3.9e-20 71.3 0.2 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.15 KFP02970.1 - 4.7e-19 67.8 9.0 4.7e-19 67.8 6.2 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ELM2 PF01448.19 KFP02971.1 - 6e-12 46.0 0.0 6e-12 46.0 0.0 3.5 3 0 0 3 3 3 1 ELM2 domain zf-C2H2 PF00096.21 KFP02971.1 - 3e-08 33.5 8.5 0.093 13.1 0.2 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFP02971.1 - 2.2e-07 30.5 8.4 0.00063 19.5 0.0 3.9 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFP02971.1 - 2.7e-07 30.4 5.0 0.42 11.0 0.5 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger Myb_DNA-binding PF00249.26 KFP02971.1 - 0.00027 20.9 0.2 0.00064 19.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_jaz PF12171.3 KFP02971.1 - 0.00095 19.2 1.2 0.76 10.0 0.3 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP02971.1 - 0.005 16.9 5.3 0.052 13.7 0.1 4.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFP02971.1 - 0.0078 16.3 0.0 0.0078 16.3 0.0 4.1 4 1 0 4 4 4 1 C2H2 type zinc-finger (2 copies) Ribosomal_S10 PF00338.17 KFP02972.1 - 4.4e-23 80.9 0.1 5.8e-23 80.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1253 PF06862.7 KFP02973.1 - 8.5e-166 551.7 5.6 1.1e-165 551.3 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) C2 PF00168.25 KFP02974.1 - 4.4e-20 71.3 0.0 2.4e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 C2 domain Bcr-Abl_Oligo PF09036.5 KFP02974.1 - 0.036 14.0 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain PI3K_C2 PF00792.19 KFP02974.1 - 0.059 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 SERTA PF06031.8 KFP02975.1 - 8.6e-17 60.1 0.2 1.5e-16 59.3 0.2 1.4 1 0 0 1 1 1 1 SERTA motif MBOAT PF03062.14 KFP02976.1 - 8.4e-39 133.5 25.4 1.2e-38 133.0 17.6 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ion_trans PF00520.26 KFP02977.1 - 1.4e-24 86.5 2.9 2.8e-24 85.4 2.0 1.5 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.1 KFP02977.1 - 4.7e-17 62.2 0.0 1.2e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain cNMP_binding PF00027.24 KFP02977.1 - 5.8e-14 51.6 0.1 2.1e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 KFP02977.1 - 1.1e-12 47.5 3.2 3.5e-12 45.8 2.2 1.9 1 0 0 1 1 1 1 Ion channel PAS PF00989.19 KFP02977.1 - 9.8e-07 28.5 0.1 4.5e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 KFP02977.1 - 0.00035 20.6 0.0 0.00091 19.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold Ion_trans_N PF08412.5 KFP02977.1 - 0.0082 15.4 0.1 0.021 14.0 0.1 1.7 1 0 0 1 1 1 1 Ion transport protein N-terminal Cupin_3 PF05899.7 KFP02977.1 - 0.0088 15.4 0.3 0.042 13.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF861) PAS_4 PF08448.5 KFP02977.1 - 0.021 14.8 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Cupin_2 PF07883.6 KFP02977.1 - 0.025 14.0 0.1 0.062 12.8 0.1 1.6 1 0 0 1 1 1 0 Cupin domain Myb_DNA-binding PF00249.26 KFP02978.1 - 3.1e-18 65.5 0.0 8e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFP02978.1 - 7.5e-06 25.9 2.3 0.004 17.2 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.19 KFP02978.1 - 0.00091 19.8 0.0 0.004 17.7 0.0 2.2 1 0 0 1 1 1 1 ELM2 domain MATH PF00917.21 KFP02979.1 - 3.4e-23 82.1 0.0 1e-22 80.5 0.0 1.9 1 0 0 1 1 1 1 MATH domain zf-TRAF PF02176.13 KFP02979.1 - 9.3e-23 80.3 24.1 4e-14 52.7 4.4 4.1 3 1 1 4 4 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 KFP02979.1 - 5.4e-06 26.3 6.1 5.4e-06 26.3 4.2 4.7 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP02979.1 - 1.4e-05 24.6 6.0 1.4e-05 24.6 4.2 4.6 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP02979.1 - 6.9e-05 22.6 5.5 6.9e-05 22.6 3.8 3.5 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFP02979.1 - 0.00052 19.6 6.3 0.00052 19.6 4.4 4.5 4 2 0 4 4 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP02979.1 - 0.00078 19.2 6.6 0.00078 19.2 4.6 3.9 3 1 0 3 3 2 1 Ring finger domain zf-RING_6 PF14835.1 KFP02979.1 - 0.013 15.2 3.1 0.013 15.2 2.2 2.6 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RAG1 PF10426.4 KFP02979.1 - 0.014 15.3 4.5 0.58 10.1 0.1 3.3 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain DUF4279 PF14106.1 KFP02979.1 - 0.029 14.2 4.2 0.3 10.9 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) Coat_F PF07875.7 KFP02979.1 - 0.29 11.2 4.4 8.1 6.6 0.1 3.0 3 0 0 3 3 2 0 Coat F domain Tropomyosin_1 PF12718.2 KFP02979.1 - 2.6 7.9 13.5 5.1 6.9 9.3 1.5 1 0 0 1 1 1 0 Tropomyosin like RD3 PF14473.1 KFP02980.1 - 8.4e-49 164.4 2.1 1.1e-48 164.0 1.5 1.2 1 0 0 1 1 1 1 RD3 protein Herpes_UL49_1 PF03117.9 KFP02980.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 UL49 family RB_B PF01857.15 KFP02980.1 - 0.099 12.1 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Cation_efflux PF01545.16 KFP02981.1 - 8.3e-45 153.0 0.0 1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family DctQ PF04290.7 KFP02981.1 - 0.062 13.0 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Pkinase PF00069.20 KFP02982.1 - 3.6e-55 186.9 1.2 6.7e-55 186.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP02982.1 - 4.4e-40 137.4 0.7 2.5e-39 134.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP02982.1 - 1.3e-08 34.1 0.0 2.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP02982.1 - 0.002 17.9 1.8 0.1 12.2 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family NCD1 PF04904.8 KFP02982.1 - 0.023 14.4 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) DUF4355 PF14265.1 KFP02982.1 - 0.13 12.1 7.7 0.38 10.7 5.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF4200 PF13863.1 KFP02982.1 - 0.13 12.1 13.6 0.35 10.8 9.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3552 PF12072.3 KFP02982.1 - 1.8 7.7 17.1 0.053 12.7 7.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Acyltransferase PF01553.16 KFP02983.1 - 6.3e-08 32.1 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase HEAT_2 PF13646.1 KFP02984.1 - 5.1e-05 23.4 6.2 0.46 10.7 0.1 4.6 4 1 0 4 4 4 2 HEAT repeats TPR_6 PF13174.1 KFP02984.1 - 0.0024 18.2 1.4 2.5 8.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFP02984.1 - 0.18 11.7 0.5 10 6.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat FANCI_S2 PF14676.1 KFP02984.1 - 0.22 11.4 10.6 0.27 11.0 0.6 3.5 3 0 0 3 3 3 0 FANCI solenoid 2 HEAT_EZ PF13513.1 KFP02984.1 - 0.51 10.8 3.6 6.1 7.4 0.1 4.0 4 0 0 4 4 4 0 HEAT-like repeat WD40 PF00400.27 KFP02985.1 - 3.6e-28 96.3 8.5 2.3e-07 30.4 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat B56 PF01603.15 KFP02986.1 - 1.3e-176 587.1 9.8 1.6e-176 586.9 6.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cytochrom_B561 PF03188.11 KFP02986.1 - 0.043 13.6 0.3 0.071 12.9 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 TMEM206 PF15122.1 KFP02987.1 - 4.6e-175 580.5 2.4 5.3e-175 580.3 1.6 1.0 1 0 0 1 1 1 1 TMEM206 protein family Cyt-b5 PF00173.23 KFP02988.1 - 8.3e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain bZIP_1 PF00170.16 KFP02989.1 - 1.6e-11 43.9 19.6 2.8e-11 43.1 13.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP02989.1 - 1e-10 41.2 18.9 1.6e-10 40.6 13.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFP02989.1 - 7.6e-08 32.5 7.9 7.6e-08 32.5 5.5 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor SNAPc19 PF15497.1 KFP02989.1 - 0.0022 18.1 1.5 0.0022 18.1 1.0 1.9 2 0 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 AOX PF01786.12 KFP02989.1 - 0.017 14.5 0.2 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Alternative oxidase Seryl_tRNA_N PF02403.17 KFP02989.1 - 0.041 13.9 6.8 0.062 13.3 4.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Vps51 PF08700.6 KFP02989.1 - 0.077 12.8 2.5 0.17 11.7 1.7 1.6 1 0 0 1 1 1 0 Vps51/Vps67 DivIC PF04977.10 KFP02989.1 - 0.083 12.3 6.9 0.19 11.2 4.8 1.6 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 KFP02989.1 - 0.18 10.7 8.9 0.23 10.4 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Macoilin PF09726.4 KFP02989.1 - 0.32 9.2 9.7 0.38 8.9 6.7 1.0 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 KFP02989.1 - 0.34 8.7 3.6 0.38 8.5 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 KFP02989.1 - 1.1 8.9 7.8 1.7 8.3 4.9 1.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ribosomal_L6e PF01159.14 KFP02989.1 - 1.3 9.2 7.3 3 8.1 5.0 1.6 1 1 1 2 2 2 0 Ribosomal protein L6e CDC37_N PF03234.9 KFP02989.1 - 9 6.5 11.8 43 4.3 8.2 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Mis14 PF08641.7 KFP02990.1 - 4.9e-16 59.0 0.2 9e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like TatD_DNase PF01026.16 KFP02991.1 - 8.1e-48 162.8 0.1 2.2e-47 161.4 0.0 1.6 1 1 0 1 1 1 1 TatD related DNase Flexi_CP_N PF08358.5 KFP02991.1 - 0.01 15.5 0.1 0.035 13.8 0.0 1.9 2 0 0 2 2 2 0 Carlavirus coat MFS_1 PF07690.11 KFP02992.1 - 3.4e-28 98.3 33.1 3.4e-28 98.3 23.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_UL45 PF05473.7 KFP02992.1 - 4.9 6.5 6.4 1.5 8.2 0.1 2.9 3 1 0 3 3 3 0 UL45 protein Exo_endo_phos PF03372.18 KFP02993.1 - 1.9e-25 90.2 0.0 2.7e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFP02993.1 - 0.044 13.3 1.0 0.33 10.5 0.0 2.8 4 0 0 4 4 4 0 Endonuclease-reverse transcriptase Pkinase PF00069.20 KFP02994.1 - 5.3e-27 94.5 0.0 7e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain MIT PF04212.13 KFP02994.1 - 5.7e-21 74.1 1.8 1.1e-20 73.2 1.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PX PF00787.19 KFP02994.1 - 1.7e-12 47.1 0.3 3.3e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.12 KFP02994.1 - 5.7e-12 45.2 0.0 4.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFP02994.1 - 3.7e-05 22.8 0.0 6.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2996 PF11210.3 KFP02994.1 - 0.08 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) HPD PF05044.7 KFP02995.1 - 1.1e-87 291.6 1.9 2e-87 290.7 1.3 1.4 1 0 0 1 1 1 1 Homeo-prospero domain Metal_resist PF13801.1 KFP02995.1 - 0.023 14.6 10.9 0.018 15.0 5.9 2.0 2 0 0 2 2 2 0 Heavy-metal resistance NifQ PF04891.7 KFP02995.1 - 0.034 14.2 2.3 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 NifQ DUF3138 PF11336.3 KFP02995.1 - 0.14 10.3 0.8 6.8 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF2968 PF11180.3 KFP02995.1 - 0.2 11.0 15.5 0.42 9.9 10.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4613 PF15390.1 KFP02995.1 - 0.21 9.7 6.2 0.34 9.0 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF1640 PF07798.6 KFP02995.1 - 0.57 10.2 6.7 1.4 8.9 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4407 PF14362.1 KFP02995.1 - 0.8 8.6 9.0 1.2 8.0 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 KFP02995.1 - 1.2 7.4 4.1 1.9 6.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nop25 PF09805.4 KFP02995.1 - 1.9 8.5 17.4 0.85 9.6 10.3 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) IncA PF04156.9 KFP02995.1 - 5.1 6.6 11.4 9.2 5.8 7.9 1.3 1 0 0 1 1 1 0 IncA protein FliD_N PF02465.13 KFP02995.1 - 5.7 7.3 7.6 59 4.1 5.1 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SET PF00856.23 KFP02996.1 - 4.2e-12 46.6 0.1 8.2e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 SET domain TPR_12 PF13424.1 KFP02996.1 - 3.8e-05 23.5 0.0 8.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFP02996.1 - 0.016 14.8 0.1 0.042 13.4 0.0 1.8 1 1 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 KFP02996.1 - 0.02 14.7 0.2 0.76 9.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.4 KFP02996.1 - 0.059 12.7 1.3 1.1 8.6 0.0 2.9 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_14 PF13428.1 KFP02996.1 - 0.084 13.5 0.0 0.68 10.7 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP02996.1 - 0.085 12.6 0.1 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP02996.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CENP-F_N PF10481.4 KFP02997.1 - 2.4e-69 234.0 26.6 2.6e-69 233.9 18.4 1.0 1 0 0 1 1 1 1 Cenp-F N-terminal domain Myosin_tail_1 PF01576.14 KFP02997.1 - 0.011 13.5 22.3 0.035 11.8 8.2 2.0 1 1 1 2 2 2 0 Myosin tail IncA PF04156.9 KFP02997.1 - 0.013 15.1 25.8 0.015 14.8 17.9 1.0 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 KFP02997.1 - 0.014 14.6 1.3 0.016 14.3 0.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KFP02997.1 - 0.03 14.2 14.2 0.3 11.0 1.5 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 KFP02997.1 - 0.039 12.9 19.1 0.047 12.7 13.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 KFP02997.1 - 0.058 12.0 18.9 0.066 11.8 13.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.14 KFP02997.1 - 0.065 12.7 17.3 0.13 11.8 12.0 1.5 1 1 0 1 1 1 0 GrpE Filament PF00038.16 KFP02997.1 - 0.068 12.6 19.2 0.055 12.9 10.2 1.8 1 1 0 1 1 1 0 Intermediate filament protein DUF4463 PF14703.1 KFP02997.1 - 0.16 12.5 7.5 0.24 11.9 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) TPR_MLP1_2 PF07926.7 KFP02997.1 - 0.17 11.6 25.1 0.07 12.8 10.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC PF04632.7 KFP02997.1 - 0.18 10.2 1.8 0.19 10.1 1.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hemerythrin PF01814.18 KFP02997.1 - 0.25 11.5 2.3 0.69 10.0 0.6 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF1395 PF07160.7 KFP02997.1 - 0.27 10.6 11.2 0.33 10.4 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Tropomyosin_1 PF12718.2 KFP02997.1 - 0.28 11.0 25.1 1.9 8.3 17.4 1.9 1 1 0 1 1 1 0 Tropomyosin like DUF342 PF03961.8 KFP02997.1 - 0.32 9.3 14.4 0.37 9.1 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IFT57 PF10498.4 KFP02997.1 - 0.34 9.6 17.8 0.37 9.4 12.3 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.10 KFP02997.1 - 0.34 10.0 14.9 0.38 9.8 10.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pox_A_type_inc PF04508.7 KFP02997.1 - 0.36 10.7 16.6 8.9 6.3 0.3 4.5 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Macoilin PF09726.4 KFP02997.1 - 0.41 8.8 17.4 0.46 8.6 12.0 1.0 1 0 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 KFP02997.1 - 0.43 10.4 26.2 0.047 13.6 10.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2205 PF10224.4 KFP02997.1 - 0.47 10.0 15.7 0.15 11.6 8.1 2.1 1 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Prominin PF05478.6 KFP02997.1 - 0.55 7.7 7.7 0.62 7.5 5.3 1.1 1 0 0 1 1 1 0 Prominin YlqD PF11068.3 KFP02997.1 - 0.6 10.1 23.0 0.49 10.4 9.0 2.1 1 1 1 2 2 2 0 YlqD protein Spc24 PF08286.6 KFP02997.1 - 0.6 9.8 20.4 0.68 9.6 6.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMCO5 PF14992.1 KFP02997.1 - 0.71 8.9 19.1 0.82 8.7 13.2 1.0 1 0 0 1 1 1 0 TMCO5 family CENP-F_leu_zip PF10473.4 KFP02997.1 - 0.71 9.7 25.6 1.6 8.6 17.7 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.9 KFP02997.1 - 0.74 9.7 24.5 1.5 8.7 17.0 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) THOC7 PF05615.8 KFP02997.1 - 0.76 10.0 18.5 0.86 9.8 6.1 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 Atg14 PF10186.4 KFP02997.1 - 0.92 8.3 21.6 1.4 7.7 15.0 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PspA_IM30 PF04012.7 KFP02997.1 - 0.94 8.7 20.2 0.079 12.3 8.8 2.0 1 1 1 2 2 2 0 PspA/IM30 family DUF848 PF05852.6 KFP02997.1 - 1 9.2 15.8 2.8 7.7 10.8 1.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Bacillus_HBL PF05791.6 KFP02997.1 - 1.1 8.6 16.9 0.8 9.0 7.3 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) 5_nucleotid PF05761.9 KFP02997.1 - 1.2 7.5 8.2 1.3 7.4 5.7 1.1 1 0 0 1 1 1 0 5' nucleotidase family Ax_dynein_light PF10211.4 KFP02997.1 - 1.2 8.9 22.1 0.028 14.2 8.6 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF3829 PF12889.2 KFP02997.1 - 1.4 8.0 11.6 1.6 7.8 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3584 PF12128.3 KFP02997.1 - 1.4 6.1 19.5 1.6 5.9 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HlyD PF00529.15 KFP02997.1 - 1.6 7.9 14.9 1.8 7.7 10.3 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Mnd1 PF03962.10 KFP02997.1 - 1.7 8.2 20.8 3.1 7.4 14.4 1.4 1 1 0 1 1 1 0 Mnd1 family COG2 PF06148.6 KFP02997.1 - 2 8.2 13.5 2.2 8.1 6.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-Q PF13094.1 KFP02997.1 - 2.2 8.3 24.0 8.3 6.4 16.6 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cytochrom_B562 PF07361.6 KFP02997.1 - 2.3 8.6 11.8 88 3.5 8.2 2.5 1 1 0 1 1 1 0 Cytochrome b562 Sulfatase_C PF14707.1 KFP02997.1 - 2.4 8.4 4.8 1.4 9.1 0.7 1.9 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF87 PF01935.12 KFP02997.1 - 3 7.5 9.1 3.7 7.2 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2664 PF10867.3 KFP02997.1 - 3.1 8.4 12.0 0.89 10.2 5.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) DUF972 PF06156.8 KFP02997.1 - 3.2 8.1 17.3 3.5 8.0 7.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 KFP02997.1 - 3.6 7.6 16.6 7.1 6.7 11.5 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KFP02997.1 - 4.2 7.1 12.3 7.5 6.3 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 KFP02997.1 - 4.5 5.6 18.4 7.6 4.8 12.8 1.4 1 1 0 1 1 1 0 AAA domain LMBR1 PF04791.11 KFP02997.1 - 4.5 5.7 6.9 5 5.6 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.6 KFP02997.1 - 4.9 6.9 23.0 1.3e+02 2.2 2.2 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.1 KFP02997.1 - 4.9 6.2 24.8 8.2 5.5 17.2 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding RRF_GI PF12614.3 KFP02997.1 - 5 6.9 11.6 2.7 7.8 5.8 1.9 1 1 1 2 2 2 0 Ribosome recycling factor Jnk-SapK_ap_N PF09744.4 KFP02997.1 - 5.1 7.0 20.1 12 5.9 14.0 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Fmp27_WPPW PF10359.4 KFP02997.1 - 5.2 5.3 14.8 6.4 5.0 10.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Striatin PF08232.7 KFP02997.1 - 5.3 7.3 19.6 31 4.8 13.6 1.9 1 1 0 1 1 1 0 Striatin family TMF_TATA_bd PF12325.3 KFP02997.1 - 5.9 6.6 21.0 3.5 7.3 11.1 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3552 PF12072.3 KFP02997.1 - 6.8 5.8 26.4 4.5 6.4 12.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF641 PF04859.7 KFP02997.1 - 6.9 6.4 16.9 8.7 6.1 4.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Borrelia_P83 PF05262.6 KFP02997.1 - 8.1 4.5 16.0 9 4.4 11.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DivIC PF04977.10 KFP02997.1 - 8.2 5.9 26.5 6 6.4 5.2 3.1 1 1 2 3 3 3 0 Septum formation initiator Rootletin PF15035.1 KFP02998.1 - 0.00081 19.4 9.4 0.001 19.1 6.5 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Filament PF00038.16 KFP02998.1 - 0.0013 18.3 13.7 0.0048 16.4 9.5 1.7 1 1 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 KFP02998.1 - 0.0054 16.3 18.3 0.0062 16.1 12.7 1.0 1 0 0 1 1 1 1 IncA protein V-SNARE PF05008.10 KFP02998.1 - 0.0054 16.8 13.0 0.027 14.6 3.0 2.3 1 1 1 2 2 2 1 Vesicle transport v-SNARE protein N-terminus BLOC1_2 PF10046.4 KFP02998.1 - 0.0088 16.1 6.0 0.0088 16.1 4.1 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 KFP02998.1 - 0.013 15.3 7.0 0.035 13.9 4.9 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 KFP02998.1 - 0.02 15.2 1.6 0.02 15.2 1.1 2.1 1 1 1 2 2 2 0 SlyX Spc7 PF08317.6 KFP02998.1 - 0.026 13.2 17.3 0.03 12.9 12.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Ufd2P_core PF10408.4 KFP02998.1 - 0.027 12.7 5.3 0.02 13.1 2.9 1.2 1 1 0 1 1 1 0 Ubiquitin elongating factor core AAA_13 PF13166.1 KFP02998.1 - 0.034 12.6 14.9 0.041 12.3 10.3 1.0 1 0 0 1 1 1 0 AAA domain FliJ PF02050.11 KFP02998.1 - 0.036 14.1 11.7 0.16 12.0 7.2 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein Syntaxin PF00804.20 KFP02998.1 - 0.083 13.0 12.1 0.14 12.3 8.4 1.4 1 1 0 1 1 1 0 Syntaxin DUF724 PF05266.9 KFP02998.1 - 0.13 11.9 14.6 0.23 11.0 10.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4200 PF13863.1 KFP02998.1 - 0.15 12.0 19.7 0.76 9.7 13.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Spectrin PF00435.16 KFP02998.1 - 0.15 12.3 13.5 0.14 12.4 4.3 2.0 1 1 1 2 2 2 0 Spectrin repeat MAD PF05557.8 KFP02998.1 - 0.25 9.3 16.8 0.27 9.2 11.6 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Atg14 PF10186.4 KFP02998.1 - 0.25 10.2 13.5 0.32 9.9 9.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC155 PF14662.1 KFP02998.1 - 0.27 10.7 18.0 0.68 9.4 12.5 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF2664 PF10867.3 KFP02998.1 - 0.43 11.2 5.8 0.53 10.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) Mnd1 PF03962.10 KFP02998.1 - 0.44 10.1 14.9 0.74 9.4 10.3 1.4 1 1 0 1 1 1 0 Mnd1 family Med9 PF07544.8 KFP02998.1 - 0.52 10.0 11.4 85 2.9 7.9 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 KFP02998.1 - 0.77 9.5 10.2 1.1 9.0 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 KFP02998.1 - 0.79 10.1 11.3 43 4.5 3.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fmp27_WPPW PF10359.4 KFP02998.1 - 0.8 8.0 11.3 0.91 7.8 7.1 1.5 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DivIVA PF05103.8 KFP02998.1 - 0.83 9.7 16.3 3.5 7.6 10.6 1.9 1 1 0 1 1 1 0 DivIVA protein APG6 PF04111.7 KFP02998.1 - 0.85 8.6 16.3 1.3 7.9 11.3 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 KFP02998.1 - 0.93 9.4 9.3 0.28 11.0 1.2 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Sipho_Gp157 PF05565.6 KFP02998.1 - 0.95 9.0 12.6 0.99 8.9 2.6 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 P4Ha_N PF08336.6 KFP02998.1 - 1 9.1 11.2 2.4 7.9 2.5 2.4 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Seryl_tRNA_N PF02403.17 KFP02998.1 - 1.1 9.2 17.3 3.1 7.8 3.8 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Glyco_hydro_63 PF03200.11 KFP02998.1 - 1.1 6.9 7.6 1.2 6.8 5.3 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase ACCA PF03255.9 KFP02998.1 - 1.2 8.6 12.1 0.82 9.2 2.8 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 PF08614.6 KFP02998.1 - 1.4 8.7 16.9 4.2 7.1 11.7 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 KFP02998.1 - 1.5 8.5 17.8 1.8 8.3 4.7 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF45 PF01863.12 KFP02998.1 - 1.7 8.3 7.5 1.9 8.2 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF45 Jnk-SapK_ap_N PF09744.4 KFP02998.1 - 1.9 8.4 15.9 2.2 8.2 11.0 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cep57_MT_bd PF06657.8 KFP02998.1 - 2.3 8.2 11.4 5 7.1 0.5 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.3 KFP02998.1 - 2.6 7.9 18.2 0.82 9.5 6.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF848 PF05852.6 KFP02998.1 - 2.8 7.7 12.6 7 6.4 8.7 1.6 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) V_ATPase_I PF01496.14 KFP02998.1 - 2.8 5.6 10.2 4 5.1 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 KFP02998.1 - 2.9 7.0 9.9 0.97 8.6 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FliD_N PF02465.13 KFP02998.1 - 3 8.2 7.3 3 8.2 2.6 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Utp12 PF04003.7 KFP02998.1 - 3.2 7.7 5.9 20 5.1 0.2 2.7 1 1 1 2 2 2 0 Dip2/Utp12 Family Rho_Binding PF08912.6 KFP02998.1 - 3.4 8.0 19.7 0.099 12.9 2.5 2.6 2 1 0 2 2 2 0 Rho Binding HR1 PF02185.11 KFP02998.1 - 4.1 7.2 18.2 2.8 7.7 3.1 2.9 1 1 1 2 2 2 0 Hr1 repeat DUF1640 PF07798.6 KFP02998.1 - 4.2 7.3 14.2 22 5.0 9.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Tnp_P_element PF12017.3 KFP02998.1 - 4.8 6.3 11.5 0.91 8.6 3.3 2.0 1 1 1 2 2 2 0 Transposase protein DUF641 PF04859.7 KFP02998.1 - 5 6.8 13.1 7.1 6.3 3.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.8 KFP02998.1 - 5.4 5.9 10.2 7.1 5.5 7.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.12 KFP02998.1 - 5.7 6.6 15.1 13 5.4 2.1 2.9 1 1 1 2 2 2 0 Prefoldin subunit PEP-utilisers_N PF05524.8 KFP02998.1 - 5.8 6.7 6.1 7.5 6.3 0.8 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4446 PF14584.1 KFP02998.1 - 6.4 6.5 10.2 4.7 7.0 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF342 PF03961.8 KFP02998.1 - 7 4.9 15.2 11 4.3 10.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Vfa1 PF08432.5 KFP02998.1 - 7.7 6.4 12.8 13 5.7 8.9 1.4 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CENP-F_C_Rb_bdg PF10490.4 KFP02999.1 - 5.8e-07 28.7 0.1 1.8e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF4572 PF15139.1 KFP02999.1 - 0.0089 15.8 1.9 0.012 15.4 1.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4572) DUF382 PF04037.8 KFP02999.1 - 0.11 12.3 1.0 0.25 11.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF382) DUF87 PF01935.12 KFP02999.1 - 0.31 10.8 2.6 0.42 10.4 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 Trehalase_Ca-bi PF07492.6 KFP02999.1 - 0.45 9.8 2.8 0.41 10.0 0.3 2.1 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain Phage_Gp23 PF10669.4 KFP02999.1 - 2.4 8.2 5.9 0.36 10.9 0.8 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) V_ATPase_I PF01496.14 KFP02999.1 - 4.4 5.0 6.4 4.7 4.9 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ion_trans_2 PF07885.11 KFP03000.1 - 4.8e-39 131.9 30.3 3.9e-19 68.1 2.1 4.0 3 1 1 4 4 4 3 Ion channel bZIP_Maf PF03131.12 KFP03000.1 - 0.0048 17.1 0.6 0.0093 16.2 0.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4079 PF13301.1 KFP03000.1 - 0.017 15.1 0.6 0.017 15.1 0.4 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) DUF872 PF05915.7 KFP03000.1 - 0.14 11.9 1.3 3.9 7.3 0.3 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3139 PF11337.3 KFP03000.1 - 2.4 8.4 6.0 2.1 8.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Hormone_recep PF00104.25 KFP03001.1 - 3.3e-36 124.3 0.3 4.7e-36 123.8 0.2 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP03001.1 - 5.5e-31 106.6 12.3 1.1e-30 105.6 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) GAT PF03127.9 KFP03001.1 - 0.1 12.5 1.1 6.4 6.8 0.1 2.4 2 0 0 2 2 2 0 GAT domain G-patch PF01585.18 KFP03002.1 - 2.2e-16 59.3 1.9 4.2e-16 58.4 1.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFP03002.1 - 3.8e-08 33.0 0.2 3.8e-08 33.0 0.1 2.7 3 0 0 3 3 3 1 DExH-box splicing factor binding site IQ PF00612.22 KFP03003.1 - 6.9e-15 53.2 23.2 1.6e-05 24.1 1.6 4.0 4 0 0 4 4 4 3 IQ calmodulin-binding motif IL32 PF15225.1 KFP03003.1 - 0.098 12.6 2.5 2.5 8.0 0.1 2.4 1 1 1 2 2 2 0 Interleukin 32 Rrp15p PF07890.7 KFP03004.1 - 1.3e-40 138.4 14.2 2.3e-40 137.6 9.9 1.4 1 0 0 1 1 1 1 Rrp15p Tox-ART-HYE1 PF15634.1 KFP03004.1 - 0.021 13.8 2.6 0.031 13.2 1.8 1.2 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase TGFb_propeptide PF00688.13 KFP03005.1 - 1.3e-36 126.1 0.1 2e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFP03005.1 - 5.9e-31 106.8 2.1 1.6e-30 105.4 1.4 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain Abhydrolase_2 PF02230.11 KFP03006.1 - 2.6e-37 128.3 0.0 3e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFP03006.1 - 1.4e-09 37.8 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP03006.1 - 9.3e-08 32.2 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFP03006.1 - 1.2e-06 28.3 0.0 0.00042 19.9 0.0 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFP03006.1 - 1.9e-05 23.9 0.4 0.0056 15.9 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Lipase_3 PF01764.20 KFP03006.1 - 0.00082 19.0 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KFP03006.1 - 0.0036 16.8 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KFP03006.1 - 0.0054 16.1 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 KFP03006.1 - 0.0096 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Thioesterase PF00975.15 KFP03006.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.7 1 1 1 2 2 2 0 Thioesterase domain Yae1_N PF09811.4 KFP03008.1 - 4.4e-19 67.7 66.0 1.5e+04 -25.3 45.7 5.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal HMG_box PF00505.14 KFP03010.1 - 2.2e-26 91.9 2.2 1.7e-25 89.0 2.2 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP03010.1 - 1.1e-08 35.2 0.6 2.3e-08 34.2 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain Thymidylate_kin PF02223.12 KFP03011.1 - 2e-09 37.1 0.2 1.2e-08 34.5 0.1 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 KFP03011.1 - 0.00081 19.2 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP03011.1 - 0.0027 17.6 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain PPK2 PF03976.9 KFP03011.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) AAA_17 PF13207.1 KFP03011.1 - 0.029 15.2 0.0 0.041 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFP03011.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KFP03011.1 - 0.094 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.16 KFP03011.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Radical_SAM PF04055.16 KFP03012.1 - 4.8e-15 56.1 0.1 1.8e-14 54.2 0.0 2.0 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 KFP03012.1 - 1.5e-09 37.9 0.6 4.5e-09 36.3 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KFP03012.1 - 3.8e-09 36.7 0.3 7.6e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain IBR PF01485.16 KFP03013.1 - 8.2e-19 67.2 27.3 1.1e-12 47.5 8.2 4.7 4 1 1 5 5 5 2 IBR domain zf-RING_2 PF13639.1 KFP03013.1 - 0.013 15.3 7.0 0.013 15.3 4.9 4.0 3 1 1 4 4 4 0 Ring finger domain Histone PF00125.19 KFP03014.1 - 3.7e-26 91.0 0.1 5.2e-26 90.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFP03014.1 - 8.6e-07 28.9 0.3 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFP03014.1 - 0.0028 17.8 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2606 PF10794.4 KFP03014.1 - 0.077 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) AMP-binding PF00501.23 KFP03015.1 - 2.6e-10 39.3 0.0 3.2e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFP03015.1 - 0.014 16.3 0.2 0.021 15.7 0.1 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain LRR_4 PF12799.2 KFP03016.1 - 8.3e-25 85.9 35.3 5.3e-08 32.2 4.0 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFP03016.1 - 5.4e-19 68.4 14.0 2.4e-11 43.5 1.9 4.0 2 1 0 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.1 KFP03016.1 - 1.6e-13 50.2 38.8 9.6e-07 28.4 6.3 5.9 2 1 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 KFP03016.1 - 2.5e-05 23.7 37.7 0.87 9.8 0.3 8.5 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 KFP03016.1 - 0.00012 21.6 15.6 2.5 8.6 0.1 7.6 5 1 1 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 KFP03016.1 - 0.00089 19.0 25.6 3 8.2 0.4 8.0 4 1 4 8 8 8 3 Leucine Rich repeat DUF2322 PF10084.4 KFP03016.1 - 0.31 10.7 3.3 2.5 7.8 0.1 3.5 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) MUG2_C PF08593.5 KFP03016.1 - 0.37 11.0 4.2 17 5.7 0.1 3.8 3 0 0 3 3 3 0 Meiotically up-regulated glycoproteins C-terminal La PF05383.12 KFP03017.1 - 1.2e-22 79.4 0.2 2.7e-22 78.3 0.2 1.6 1 0 0 1 1 1 1 La domain RE_HaeIII PF09556.5 KFP03017.1 - 0.09 11.6 0.2 2.6 6.8 0.1 2.1 1 1 1 2 2 2 0 HaeIII restriction endonuclease DUF2186 PF09952.4 KFP03017.1 - 0.12 12.6 0.2 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) A_deaminase PF00962.17 KFP03018.1 - 7e-43 146.8 0.0 8.1e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase TM2 PF05154.11 KFP03019.1 - 1.7e-14 53.7 8.3 2.6e-14 53.1 5.8 1.3 1 0 0 1 1 1 1 TM2 domain tRNA-synt_2b PF00587.20 KFP03020.1 - 2.8e-43 147.4 0.2 4.9e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFP03020.1 - 1.7e-19 69.5 0.1 4.2e-19 68.2 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KFP03020.1 - 4e-13 49.0 0.1 9.1e-13 47.8 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KFP03020.1 - 1.7e-12 46.9 0.0 2.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain PDZ PF00595.19 KFP03021.1 - 9.3e-50 166.7 7.2 4.7e-16 58.7 0.1 3.5 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) ZU5 PF00791.15 KFP03021.1 - 9.6e-36 121.5 0.0 2.5e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 ZU5 domain PDZ_2 PF13180.1 KFP03021.1 - 6.6e-18 64.3 4.2 8.1e-06 25.6 0.1 3.6 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.16 KFP03021.1 - 3.2e-11 43.0 0.0 6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 KFP03021.1 - 3.5e-11 42.3 0.1 1e-10 40.9 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP03021.1 - 0.0017 17.6 0.1 0.014 14.7 0.0 2.5 2 0 0 2 2 2 1 SH3 domain DUF104 PF01954.11 KFP03021.1 - 0.097 12.7 3.5 2.3 8.3 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF104 CD20 PF04103.10 KFP03022.1 - 1.2e-13 51.2 11.1 2.1e-13 50.4 7.7 1.4 1 0 0 1 1 1 1 CD20-like family PID PF00640.18 KFP03023.1 - 2.8e-51 173.1 5.5 2.5e-50 170.0 1.7 2.4 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 KFP03023.1 - 8.9e-33 112.3 6.5 2.7e-16 59.5 0.7 2.7 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP03023.1 - 3.4e-06 26.8 0.0 0.00053 19.8 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Phage_CP76 PF06892.6 KFP03023.1 - 0.045 13.0 0.9 0.41 9.9 0.1 2.6 2 1 0 2 2 2 0 Phage regulatory protein CII (CP76) Tricorn_PDZ PF14685.1 KFP03023.1 - 0.089 12.5 0.3 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Tricorn protease PDZ domain Glyoxalase_4 PF13669.1 KFP03024.1 - 1.2e-23 83.2 0.0 1.4e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFP03024.1 - 5.6e-12 46.2 0.0 6.7e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFP03024.1 - 7.7e-12 45.3 0.0 9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFP03024.1 - 3.8e-09 36.6 0.0 4.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Mpp10 PF04006.7 KFP03025.1 - 5.6e-154 513.7 78.4 7e-154 513.4 54.3 1.0 1 0 0 1 1 1 1 Mpp10 protein VRR_NUC PF08774.6 KFP03026.1 - 9.8e-20 70.4 0.0 2e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain PRP21_like_P PF12230.3 KFP03026.1 - 0.0044 16.5 0.1 0.0089 15.5 0.1 1.5 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein zf-TRAF PF02176.13 KFP03026.1 - 0.024 15.0 0.2 0.024 15.0 0.1 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger Myotub-related PF06602.9 KFP03027.1 - 2.3e-90 302.9 2.5 9.5e-67 225.2 1.9 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain 3-PAP PF12578.3 KFP03027.1 - 8.3e-35 119.7 0.0 1.5e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-associated protein Rbsn PF11464.3 KFP03027.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain RVT_1 PF00078.22 KFP03028.1 - 3e-27 95.3 0.0 4.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFP03028.1 - 0.0035 16.8 0.1 0.0064 16.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVT_2 PF07727.9 KFP03028.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2_5 PF13909.1 KFP03029.1 - 4.4e-26 89.5 213.5 0.0019 18.3 0.7 25.3 25 0 0 25 25 25 19 C2H2-type zinc-finger domain IRK PF01007.15 KFP03031.1 - 1.1e-163 543.8 0.7 1.4e-163 543.5 0.5 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP03031.1 - 0.012 15.2 9.7 0.044 13.4 6.8 2.0 1 1 0 1 1 1 0 Ion channel Pkinase PF00069.20 KFP03032.1 - 1.7e-53 181.4 0.0 2.8e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03032.1 - 3e-22 78.9 0.0 5.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Vps26 PF03643.10 KFP03033.1 - 4.2e-67 225.8 0.2 4.8e-67 225.6 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFP03033.1 - 7.7e-06 25.7 0.1 0.00019 21.2 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain TPR_11 PF13414.1 KFP03034.1 - 2.9e-21 74.8 8.2 1.9e-13 49.8 0.0 5.0 2 2 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFP03034.1 - 9.7e-16 56.6 8.3 0.00059 19.3 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP03034.1 - 3.5e-12 45.2 13.3 0.041 13.7 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat zf-RING_2 PF13639.1 KFP03034.1 - 7.2e-10 38.5 12.9 7.2e-10 38.5 8.9 2.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFP03034.1 - 4.1e-08 33.2 8.4 4.1e-08 33.2 5.8 3.0 2 0 0 2 2 2 1 RING-H2 zinc finger TPR_16 PF13432.1 KFP03034.1 - 2.8e-05 24.6 0.0 0.72 10.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP03034.1 - 3.8e-05 23.5 7.1 0.053 13.4 0.1 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat zf-C3HC4 PF00097.20 KFP03034.1 - 7.5e-05 22.3 13.3 7.5e-05 22.3 9.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP03034.1 - 8.1e-05 22.5 13.1 8.1e-05 22.5 9.1 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.1 KFP03034.1 - 0.0002 21.6 0.4 0.47 10.8 0.0 4.0 2 2 2 4 4 4 1 Tetratricopeptide repeat zf-Apc11 PF12861.2 KFP03034.1 - 0.00088 19.0 5.5 0.00088 19.0 3.8 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_17 PF13431.1 KFP03034.1 - 0.0023 17.9 2.3 0.31 11.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP03034.1 - 0.004 16.8 3.0 16 5.5 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFP03034.1 - 0.047 14.3 0.1 75 4.3 0.0 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat PIG-P PF08510.7 KFP03035.1 - 2.3e-39 133.9 1.1 2.7e-39 133.6 0.8 1.1 1 0 0 1 1 1 1 PIG-P Ripply PF14998.1 KFP03036.1 - 5.1e-23 80.9 0.0 5.4e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Transcription Regulator BPL_N PF09825.4 KFP03038.1 - 9.6e-14 50.9 0.0 8.3e-07 28.1 0.0 2.3 1 1 0 2 2 2 2 Biotin-protein ligase, N terminal ABC_transp_aux PF09822.4 KFP03038.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC-type uncharacterized transport system ThuA PF06283.6 KFP03038.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation BPL_LplA_LipB PF03099.14 KFP03039.1 - 3.5e-18 65.8 0.0 5.6e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KFP03039.1 - 5.1e-10 38.8 0.0 1.1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain SIM_C PF06621.7 KFP03040.1 - 7.7e-67 225.9 8.1 1e-66 225.5 5.6 1.2 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.6 KFP03040.1 - 3.5e-23 81.4 0.5 1.3e-17 63.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KFP03040.1 - 2.4e-20 72.5 0.5 3e-15 56.1 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFP03040.1 - 1e-16 60.6 0.0 3e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFP03040.1 - 8.8e-05 22.1 0.4 0.00018 21.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFP03040.1 - 0.00038 20.7 0.0 0.74 10.2 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFP03040.1 - 0.0053 16.7 0.0 0.084 12.9 0.0 2.3 2 0 0 2 2 2 1 PAS fold PMP22_Claudin PF00822.15 KFP03041.1 - 2.2e-32 112.0 7.1 2.6e-32 111.7 4.9 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP03041.1 - 1.1e-12 47.9 7.0 1.4e-12 47.6 4.9 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Hormone_6 PF00236.13 KFP03041.1 - 0.26 11.1 1.3 0.44 10.3 0.9 1.3 1 0 0 1 1 1 0 Glycoprotein hormone Amastin PF07344.6 KFP03041.1 - 0.31 10.6 8.9 0.54 9.8 5.8 1.9 1 1 1 2 2 2 0 Amastin surface glycoprotein CAF-1_p60_C PF15512.1 KFP03042.1 - 2e-53 181.4 21.9 2.7e-53 181.0 15.2 1.2 1 0 0 1 1 1 1 Chromatin assembly factor complex 1 subunit p60, C-terminal WD40 PF00400.27 KFP03042.1 - 1.2e-35 120.0 9.2 7.2e-09 35.2 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFP03042.1 - 8.3e-06 25.6 1.1 0.0011 18.7 0.1 3.5 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KFP03042.1 - 4.2e-05 22.5 0.1 0.022 13.5 0.0 2.6 1 1 0 2 2 2 2 Coatomer WD associated region IKI3 PF04762.7 KFP03042.1 - 0.011 13.6 0.3 0.42 8.3 0.0 2.2 2 0 0 2 2 2 0 IKI3 family Dopey_N PF04118.9 KFP03043.1 - 3.6e-104 347.8 0.2 8e-104 346.7 0.1 1.6 1 0 0 1 1 1 1 Dopey, N-terminal adh_short PF00106.20 KFP03044.1 - 1.5e-24 86.7 0.0 2.4e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP03044.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KFP03044.1 - 0.0001 21.3 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein HATPase_c PF02518.21 KFP03044.1 - 0.041 13.6 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rubis-subs-bind PF09273.6 KFP03045.1 - 4.5e-22 78.3 0.5 9.7e-22 77.2 0.3 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KFP03045.1 - 2e-09 37.9 0.0 5.9e-09 36.4 0.0 1.8 2 1 0 2 2 2 1 SET domain Runt PF00853.14 KFP03047.1 - 6.8e-53 177.7 0.2 9.8e-53 177.2 0.1 1.2 1 0 0 1 1 1 1 Runt domain RunxI PF08504.6 KFP03047.1 - 2.7e-42 143.3 5.6 2.7e-42 143.3 3.9 1.8 2 0 0 2 2 2 1 Runx inhibition domain GST_N_3 PF13417.1 KFP03049.1 - 1.4e-08 34.7 0.0 3.5e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFP03049.1 - 9.4e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFP03049.1 - 3.7e-05 23.6 0.0 8.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFP03049.1 - 0.0031 17.4 0.3 0.035 14.0 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFP03049.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EntA_Immun PF08951.5 KFP03049.1 - 0.051 13.7 0.4 0.79 9.9 0.2 2.4 2 0 0 2 2 2 0 Enterocin A Immunity Calcipressin PF04847.7 KFP03050.1 - 3e-57 193.2 0.8 3.3e-57 193.0 0.5 1.0 1 0 0 1 1 1 1 Calcipressin ISK_Channel PF02060.10 KFP03051.1 - 1.6e-37 127.9 0.0 1.8e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Slow voltage-gated potassium channel DDE_3 PF13358.1 KFP03052.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease FAM165 PF14981.1 KFP03053.1 - 9.2e-30 101.9 4.4 9.7e-30 101.8 3.0 1.0 1 0 0 1 1 1 1 FAM165 family DUF2570 PF10828.3 KFP03053.1 - 0.034 13.7 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) MadM PF03818.8 KFP03053.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit ISK_Channel PF02060.10 KFP03054.1 - 1.9e-11 43.6 0.1 2.3e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Slow voltage-gated potassium channel DUF2207 PF09972.4 KFP03054.1 - 0.011 14.3 0.1 0.012 14.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4646 PF15496.1 KFP03054.1 - 0.016 15.2 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) OSTbeta PF15048.1 KFP03054.1 - 0.066 13.3 0.1 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein FeoB_C PF07664.7 KFP03054.1 - 0.075 12.4 0.5 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus DUF2762 PF10960.3 KFP03054.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) gpUL132 PF11359.3 KFP03054.1 - 0.099 11.9 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Zip PF02535.17 KFP03054.1 - 0.12 11.4 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4014 PF13198.1 KFP03054.1 - 0.19 12.1 1.5 0.22 11.9 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) DUF1673 PF07895.6 KFP03054.1 - 0.2 11.1 2.4 0.14 11.6 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Ribosomal_S6 PF01250.12 KFP03055.1 - 4e-12 45.8 0.0 5e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 OSCP PF00213.13 KFP03056.1 - 2e-43 148.2 0.1 2.2e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit SH3_9 PF14604.1 KFP03057.1 - 9.7e-72 236.3 10.6 3.8e-17 61.6 0.1 5.5 5 0 0 5 5 5 5 Variant SH3 domain SH3_1 PF00018.23 KFP03057.1 - 9.2e-65 213.8 14.0 3.9e-17 61.3 0.2 5.5 5 0 0 5 5 5 5 SH3 domain SH3_2 PF07653.12 KFP03057.1 - 6.9e-58 191.9 2.4 3.1e-14 52.1 0.0 5.5 5 0 0 5 5 5 5 Variant SH3 domain RhoGEF PF00621.15 KFP03057.1 - 1.3e-44 152.2 2.3 1.3e-44 152.2 1.6 2.9 3 1 0 3 3 1 1 RhoGEF domain EF-hand_4 PF12763.2 KFP03057.1 - 5.8e-31 106.3 0.0 9.2e-15 54.2 0.0 3.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 KFP03057.1 - 4.2e-18 64.9 0.0 1.1e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 KFP03057.1 - 1.3e-08 33.4 0.0 0.0033 16.6 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFP03057.1 - 1.3e-08 34.7 0.0 0.00069 19.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP03057.1 - 3.1e-06 26.5 0.0 0.47 10.4 0.0 4.0 4 0 0 4 4 3 1 EF-hand domain PH PF00169.24 KFP03057.1 - 1.1e-05 25.5 1.5 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 PH domain EF-hand_5 PF13202.1 KFP03057.1 - 0.0041 16.4 0.2 0.75 9.2 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFP03057.1 - 0.0097 15.5 0.0 0.28 10.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair ADH_zinc_N PF00107.21 KFP03058.1 - 6.5e-11 41.8 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFP03058.1 - 3.2e-06 26.8 0.1 7.5e-06 25.6 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DND1_DSRM PF14709.1 KFP03060.1 - 8.9e-19 67.5 0.1 2.6e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 G-patch PF01585.18 KFP03060.1 - 8.3e-17 60.7 2.9 2e-16 59.5 2.0 1.7 1 0 0 1 1 1 1 G-patch domain dsrm PF00035.20 KFP03060.1 - 1.3e-14 54.4 0.0 3.8e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif G-patch_2 PF12656.2 KFP03060.1 - 1.1e-06 28.3 2.2 1.9e-06 27.6 0.6 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site GARS_A PF01071.14 KFP03061.1 - 6.6e-90 299.8 0.0 1.4e-89 298.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.14 KFP03061.1 - 6.1e-66 221.4 0.1 1.4e-65 220.2 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.10 KFP03061.1 - 5.5e-41 139.0 3.5 2.3e-38 130.6 0.1 3.7 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KFP03061.1 - 4.9e-37 127.2 0.2 7.5e-36 123.4 0.0 2.9 3 0 0 3 3 3 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KFP03061.1 - 1.9e-30 104.8 0.5 9.7e-30 102.6 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KFP03061.1 - 2.6e-20 72.4 1.0 9.8e-20 70.6 0.7 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KFP03061.1 - 7.9e-14 51.7 0.0 2.5e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFP03061.1 - 2e-08 33.3 0.0 5.7e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KFP03061.1 - 0.0002 20.7 0.1 0.00058 19.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFP03061.1 - 0.00064 19.6 0.0 0.0018 18.1 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KFP03061.1 - 0.0027 17.2 0.1 0.0064 15.9 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 KFP03061.1 - 0.0081 15.4 0.3 0.025 13.8 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 KFP03061.1 - 0.014 14.8 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFP03061.1 - 0.046 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF1992 PF09350.5 KFP03062.1 - 2.7e-24 84.7 0.1 1.2e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) DnaJ PF00226.26 KFP03062.1 - 2.8e-10 39.7 0.2 2.8e-10 39.7 0.2 2.2 3 0 0 3 3 3 1 DnaJ domain DUF3597 PF12200.3 KFP03062.1 - 0.03 14.7 0.1 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) UPF0220 PF05255.6 KFP03063.1 - 1.9e-53 180.0 4.3 2.1e-53 179.9 3.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Tissue_fac PF01108.12 KFP03064.1 - 2.6e-20 72.1 0.5 2.6e-20 72.1 0.3 1.6 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.5 KFP03064.1 - 1e-16 60.8 0.3 2.4e-16 59.6 0.2 1.6 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFP03064.1 - 1.7e-09 37.7 3.1 1.2e-07 31.7 0.1 2.7 2 1 1 3 3 3 2 Fibronectin type III domain Interfer-bind PF09294.5 KFP03065.1 - 5.9e-43 145.2 0.5 7.7e-21 74.1 0.0 3.3 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFP03065.1 - 5.6e-35 119.3 10.4 7.6e-19 67.4 1.2 3.3 3 0 0 3 3 3 2 Tissue factor fn3 PF00041.16 KFP03065.1 - 1.9e-06 27.8 11.7 0.0012 18.8 0.0 4.9 5 1 0 5 5 5 2 Fibronectin type III domain Interfer-bind PF09294.5 KFP03066.1 - 4.5e-27 94.1 1.5 5.3e-27 93.9 0.0 1.7 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFP03066.1 - 0.0009 19.3 0.2 0.0009 19.3 0.2 2.1 3 0 0 3 3 3 1 Fibronectin type III domain Interfer-bind PF09294.5 KFP03067.1 - 6.2e-26 90.5 0.4 7.5e-26 90.2 0.3 1.1 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFP03067.1 - 0.028 14.5 0.4 0.048 13.7 0.3 1.3 1 0 0 1 1 1 0 Fibronectin type III domain AAL_decarboxy PF03306.8 KFP03067.1 - 0.072 12.1 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase DUF3600 PF12207.3 KFP03067.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Yae1_N PF09811.4 KFP03068.1 - 2.6e-13 49.2 34.7 26 4.4 24.1 3.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal DUF4571 PF15137.1 KFP03069.1 - 7.4e-86 287.1 5.5 8.2e-86 286.9 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) GCFC PF07842.7 KFP03070.1 - 2.4e-35 122.2 0.3 6.3e-35 120.8 0.2 1.7 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Syja_N PF02383.13 KFP03071.1 - 3.3e-83 279.1 0.1 5e-83 278.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.6 KFP03071.1 - 2.6e-55 185.9 0.1 4.6e-54 181.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.18 KFP03071.1 - 1.4e-27 97.2 0.5 2.3e-27 96.5 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_5 PF13893.1 KFP03071.1 - 0.0077 16.0 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03071.1 - 0.087 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP03071.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2870 PF11069.3 KFP03072.1 - 2.2e-45 152.6 1.8 2.2e-45 152.6 1.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) ubiquitin PF00240.18 KFP03072.1 - 0.012 14.9 1.5 0.13 11.6 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin family NodZ PF05830.6 KFP03072.1 - 0.069 11.7 0.1 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Flavi_glycop_C PF02832.11 KFP03072.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Dynamitin PF04912.9 KFP03072.1 - 0.12 11.2 4.9 0.17 10.6 0.2 2.2 2 0 0 2 2 2 0 Dynamitin FAM176 PF14851.1 KFP03073.1 - 3.2e-43 147.0 1.1 3.7e-43 146.8 0.0 1.7 2 0 0 2 2 2 1 FAM176 family Gal_Lectin PF02140.13 KFP03073.1 - 6.5e-36 122.4 7.8 1.9e-17 63.3 0.7 2.4 2 0 0 2 2 2 2 Galactose binding lectin domain Npa1 PF11707.3 KFP03074.1 - 4.8e-80 269.0 4.7 8.1e-79 265.0 0.1 3.3 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal Yippee-Mis18 PF03226.9 KFP03075.1 - 8e-18 64.2 0.4 3.2e-16 59.1 0.3 2.0 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-MYND PF01753.13 KFP03075.1 - 0.24 11.2 1.3 3.5 7.5 0.4 2.2 2 0 0 2 2 2 0 MYND finger DUF1289 PF06945.8 KFP03075.1 - 0.35 10.3 0.1 0.35 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Pkinase PF00069.20 KFP03077.1 - 8.9e-65 218.4 0.0 1.4e-64 217.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03077.1 - 1.4e-35 122.6 0.0 2.1e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP03077.1 - 6.9e-11 41.6 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP03077.1 - 5.3e-06 25.6 0.1 9.8e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP03077.1 - 4.6e-05 22.8 0.5 0.00012 21.5 0.2 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KFP03077.1 - 0.00014 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP03077.1 - 0.042 13.1 0.2 0.088 12.1 0.2 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KFP03077.1 - 0.047 13.2 1.9 0.087 12.3 0.1 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Cupin_5 PF06172.6 KFP03077.1 - 0.065 13.1 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily (DUF985) CTD_bind PF04818.8 KFP03078.1 - 2.3e-15 56.5 0.0 5.7e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.17 KFP03078.1 - 4.9e-09 35.7 0.0 9.7e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03078.1 - 4e-08 32.9 0.0 7.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03078.1 - 5.4e-07 29.4 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KFP03078.1 - 0.18 11.5 88.0 0.42 10.3 25.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Yae1_N PF09811.4 KFP03079.1 - 9.2e-14 50.6 40.0 1.1e+03 -0.9 27.7 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal ANF_receptor PF01094.23 KFP03081.1 - 1e-66 225.1 0.0 1.7e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan PF00060.21 KFP03081.1 - 9.9e-54 181.0 0.1 1.5e-53 180.4 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 KFP03081.1 - 1.3e-28 98.7 1.2 9.1e-28 96.0 0.4 2.6 3 0 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFP03081.1 - 7.6e-21 74.4 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFP03081.1 - 2.1e-08 33.9 0.0 3.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein CopK PF11525.3 KFP03081.1 - 0.1 12.2 2.0 0.11 12.2 0.2 1.8 2 0 0 2 2 2 0 Copper resistance protein K PGM_PMM_II PF02879.11 KFP03081.1 - 0.15 12.4 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II BTB PF00651.26 KFP03082.1 - 2.1e-24 85.6 0.6 4.8e-24 84.4 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain bZIP_Maf PF03131.12 KFP03082.1 - 3.1e-16 59.4 4.9 7.3e-16 58.2 3.4 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 KFP03082.1 - 1.7e-10 40.7 7.6 4e-10 39.5 5.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP03082.1 - 2.8e-07 30.2 8.8 6.2e-07 29.1 6.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Med4 PF10018.4 KFP03082.1 - 0.003 16.9 0.3 0.0074 15.7 0.2 1.6 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Orthopox_B11R PF07033.6 KFP03082.1 - 6.2 6.3 8.7 7.7 6.0 0.0 3.5 3 0 0 3 3 3 0 Orthopoxvirus B11R protein APG6 PF04111.7 KFP03083.1 - 0.0041 16.2 10.4 0.0049 15.9 7.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 GAS PF13851.1 KFP03083.1 - 0.027 13.6 15.1 0.038 13.2 10.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.4 KFP03083.1 - 0.049 13.4 10.4 0.069 12.9 7.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Occludin_ELL PF07303.8 KFP03083.1 - 0.05 14.3 7.9 0.44 11.3 0.5 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF4559 PF15112.1 KFP03083.1 - 0.078 12.1 5.7 0.1 11.7 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Mnd1 PF03962.10 KFP03083.1 - 0.091 12.4 8.2 0.12 12.0 5.7 1.2 1 0 0 1 1 1 0 Mnd1 family DUF1843 PF08898.5 KFP03083.1 - 0.17 11.9 0.4 0.17 11.9 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) CCDC-167 PF15188.1 KFP03083.1 - 0.24 11.3 9.4 0.4 10.6 6.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Nup88 PF10168.4 KFP03083.1 - 0.36 8.6 7.9 0.42 8.3 5.5 1.0 1 0 0 1 1 1 0 Nuclear pore component Seryl_tRNA_N PF02403.17 KFP03083.1 - 0.47 10.4 9.7 0.71 9.9 6.7 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 KFP03083.1 - 0.65 7.7 3.5 0.66 7.7 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cdc6_C PF09079.6 KFP03083.1 - 0.91 9.2 4.4 1.4 8.7 0.4 2.2 2 0 0 2 2 2 0 CDC6, C terminal Fmp27_WPPW PF10359.4 KFP03083.1 - 1.1 7.5 8.5 1.4 7.2 5.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.6 KFP03083.1 - 1.3 8.6 8.5 0.75 9.4 3.9 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 KFP03083.1 - 1.5 9.2 11.0 2.2 8.6 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Takusan PF04822.8 KFP03083.1 - 1.6 8.5 8.4 3.3 7.5 5.8 1.6 1 1 0 1 1 1 0 Takusan DivIVA PF05103.8 KFP03083.1 - 2.6 8.1 12.4 7.2 6.6 2.6 2.2 1 1 1 2 2 2 0 DivIVA protein CENP-H PF05837.7 KFP03083.1 - 3.2 7.9 11.7 24 5.1 8.1 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) YlqD PF11068.3 KFP03083.1 - 3.3 7.7 10.5 0.38 10.7 0.7 2.1 1 1 1 2 2 2 0 YlqD protein TMPIT PF07851.8 KFP03083.1 - 6.4 5.7 6.9 8.6 5.3 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein UCH PF00443.24 KFP03084.1 - 2.1e-49 168.0 23.0 2.1e-49 168.0 15.9 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFP03084.1 - 9.3e-23 80.1 11.4 3.2e-22 78.4 7.9 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFP03084.1 - 1.3e-16 60.9 31.3 1.9e-15 57.0 17.0 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1115 PF06544.7 KFP03085.1 - 1.9e-32 111.6 0.4 3.1e-32 110.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.17 KFP03085.1 - 1.9e-13 50.2 0.1 3.6e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 RWD domain Methyltransf_26 PF13659.1 KFP03086.1 - 5.8e-14 52.1 0.0 7.4e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP03086.1 - 2.2e-09 36.9 0.0 2.9e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KFP03086.1 - 1.7e-05 24.4 0.0 2.7e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFP03086.1 - 0.00015 20.9 0.0 0.00076 18.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 KFP03086.1 - 0.021 15.2 0.0 0.045 14.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 KFP03086.1 - 0.026 13.9 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 KFP03086.1 - 0.045 14.5 0.0 0.08 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFP03086.1 - 0.067 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KFP03086.1 - 0.069 13.5 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADAM_spacer1 PF05986.9 KFP03088.1 - 3.5e-33 113.8 0.1 5.3e-33 113.2 0.1 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFP03088.1 - 7.5e-25 87.6 0.2 1.3e-24 86.8 0.1 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 KFP03088.1 - 3.7e-13 49.8 1.2 8.3e-13 48.6 0.9 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFP03088.1 - 1.6e-12 48.0 1.8 1.6e-12 48.0 1.2 1.9 2 0 0 2 2 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.14 KFP03088.1 - 7.8e-10 38.7 19.5 4.5e-09 36.2 3.5 4.4 4 0 0 4 4 3 2 Thrombospondin type 1 domain Reprolysin_4 PF13583.1 KFP03088.1 - 1.1e-09 38.1 0.5 1.8e-09 37.4 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP03088.1 - 1.8e-09 37.8 0.9 1.8e-09 37.8 0.7 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFP03088.1 - 0.00022 20.9 1.6 0.00045 19.9 1.1 1.4 1 0 0 1 1 1 1 Matrixin DUF3285 PF11688.3 KFP03088.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Peptidase_M54 PF07998.6 KFP03088.1 - 0.074 12.8 0.1 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Toprim_Crpt PF13342.1 KFP03088.1 - 0.11 12.1 0.1 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DUF955 PF06114.8 KFP03088.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DUF1025 PF06262.6 KFP03088.1 - 0.14 11.9 0.5 0.3 10.8 0.4 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Atracotoxin PF05353.6 KFP03089.1 - 0.039 13.7 1.1 0.048 13.4 0.8 1.4 1 1 0 1 1 1 0 Delta Atracotoxin ADAM_spacer1 PF05986.9 KFP03090.1 - 2.9e-32 110.8 0.0 4.8e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFP03090.1 - 3.1e-21 75.8 0.0 4.8e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 KFP03090.1 - 2e-15 56.6 53.5 2.4e-08 33.9 4.3 5.9 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 KFP03090.1 - 8.9e-13 48.6 0.2 1.7e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFP03090.1 - 1.8e-11 44.6 0.0 3.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP03090.1 - 3e-08 33.4 0.1 4.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP03090.1 - 4.3e-07 30.1 0.1 7.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Yae1_N PF09811.4 KFP03091.1 - 4.4e-15 54.9 43.8 1.4e+04 -4.3 30.3 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF2668 PF10873.3 KFP03092.1 - 2.5e-78 261.6 20.2 2.7e-78 261.4 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) Shisa PF13908.1 KFP03092.1 - 1e-05 25.8 1.4 1e-05 25.8 1.0 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Phe_tRNA-synt_N PF02912.13 KFP03093.1 - 0.13 12.0 0.3 4.2 7.1 0.0 2.8 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain GABP-alpha PF11620.3 KFP03094.1 - 1.1e-41 140.6 1.0 2.9e-41 139.3 0.7 1.7 1 0 0 1 1 1 1 GA-binding protein alpha chain Ets PF00178.17 KFP03094.1 - 3e-39 133.0 0.5 3e-39 133.0 0.3 1.8 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFP03094.1 - 1.1e-28 98.7 0.1 3.5e-28 97.2 0.1 1.9 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Syntaxin-18_N PF10496.4 KFP03094.1 - 0.018 14.8 0.1 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus ATP-synt_F6 PF05511.6 KFP03095.1 - 3.9e-38 129.3 0.1 4.4e-38 129.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 V-set PF07686.12 KFP03096.1 - 7.7e-17 61.2 1.1 3.2e-07 30.2 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFP03096.1 - 1.2e-16 60.3 0.4 3.7e-10 39.5 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP03096.1 - 3.7e-15 55.8 3.0 2.9e-10 40.1 0.8 2.3 1 1 1 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP03096.1 - 4.3e-13 49.1 4.2 6e-07 29.4 1.0 3.3 2 2 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP03096.1 - 2e-11 44.2 4.2 1.4e-05 25.4 1.4 3.6 2 2 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFP03096.1 - 0.0077 14.5 6.0 0.44 8.7 0.0 2.8 1 1 2 3 3 3 2 Alphaherpesvirus glycoprotein E DUF4307 PF14155.1 KFP03096.1 - 0.0082 15.9 3.0 0.56 10.0 0.2 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4307) C2-set_2 PF08205.7 KFP03096.1 - 0.012 15.4 0.2 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain TMEM171 PF15471.1 KFP03096.1 - 0.05 12.3 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 TGS PF02824.16 KFP03097.1 - 8.5e-05 22.3 0.0 0.00033 20.4 0.0 2.0 2 0 0 2 2 2 1 TGS domain DUF2469 PF10611.4 KFP03097.1 - 0.00035 20.8 0.0 0.0012 19.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) tRNA_SAD PF07973.9 KFP03097.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain RVT_1 PF00078.22 KFP03098.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Keratin PF02422.11 KFP03099.1 - 9.3e-34 115.3 17.9 1e-33 115.2 12.4 1.0 1 0 0 1 1 1 1 Keratin MSSP PF03940.8 KFP03099.1 - 1.5 8.2 17.8 0.61 9.5 10.6 1.8 2 0 0 2 2 2 0 Male specific sperm protein DUF3432 PF11914.3 KFP03099.1 - 1.6 8.8 6.8 2.9 7.9 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Yae1_N PF09811.4 KFP03101.1 - 5.8e-13 48.1 34.6 19 4.9 24.0 3.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal RVT_1 PF00078.22 KFP03102.1 - 1.7e-09 37.3 0.0 3.2e-09 36.4 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AF1Q PF15017.1 KFP03102.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator DUF3235 PF11574.3 KFP03102.1 - 0.087 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) RRM_5 PF13893.1 KFP03103.1 - 0.062 13.1 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Orbi_VP6 PF01516.11 KFP03103.1 - 0.75 8.8 5.3 4.2 6.3 0.9 2.3 2 0 0 2 2 2 0 Orbivirus helicase VP6 Histone PF00125.19 KFP03104.1 - 5.2e-15 55.3 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFP03104.1 - 1.4e-05 25.2 0.1 1.8e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KFP03104.1 - 3.1e-05 23.8 0.2 4.1e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KFP03104.1 - 0.00021 21.2 0.1 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFP03104.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFP03104.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KFP03104.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Guanylate_cyc PF00211.15 KFP03106.1 - 1.6e-53 180.7 0.0 2.2e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 KFP03108.1 - 8.6e-60 201.2 0.1 1.2e-59 200.7 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Dynamin_N PF00350.18 KFP03109.1 - 1.1e-18 67.6 0.0 2.9e-17 62.9 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KFP03109.1 - 4.3e-11 42.7 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP03109.1 - 0.016 14.4 0.0 0.16 11.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Miro PF08477.8 KFP03109.1 - 0.02 15.3 0.0 0.44 11.0 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 KFP03109.1 - 0.031 13.7 0.0 0.059 12.8 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain HLH PF00010.21 KFP03110.1 - 5.3e-08 32.4 0.1 2.3e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lzipper-MIP1 PF14389.1 KFP03110.1 - 0.014 15.4 5.0 0.014 15.4 3.5 3.1 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CEP19 PF14933.1 KFP03110.1 - 0.35 11.1 7.1 0.093 13.0 2.4 1.7 2 0 0 2 2 2 0 CEP19-like protein FRG2 PF15315.1 KFP03110.1 - 1 9.3 6.6 1.5 8.8 4.6 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 zf-H2C2_2 PF13465.1 KFP03111.1 - 8.4e-15 54.2 9.1 1.1e-08 34.9 1.4 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03111.1 - 3e-10 39.7 28.0 1.5e-05 25.0 2.3 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFP03111.1 - 0.00019 21.1 0.3 0.00019 21.1 0.2 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 KFP03111.1 - 0.0037 17.4 6.3 0.0048 17.0 0.8 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFP03111.1 - 0.0076 16.5 26.2 0.026 14.8 0.9 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP03111.1 - 0.055 13.6 0.5 0.055 13.6 0.3 3.3 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP03111.1 - 2.2 8.4 7.5 3.4 7.8 3.3 2.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 KFP03111.1 - 2.5 8.1 7.1 0.72 9.8 0.3 2.9 3 1 0 3 3 3 0 Zinc ribbon domain Pam16 PF03656.8 KFP03112.1 - 2.2e-53 179.3 5.2 2.4e-53 179.2 3.6 1.0 1 0 0 1 1 1 1 Pam16 DUF1900 PF08954.6 KFP03113.1 - 2.1e-60 202.1 0.0 2.9e-30 104.5 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1900) WD40 PF00400.27 KFP03113.1 - 9.8e-25 85.4 1.5 3.9e-09 36.0 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 KFP03114.1 - 1.6e-17 62.6 2.1 3.4e-06 26.7 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Ank PF00023.25 KFP03115.1 - 4.7e-41 136.5 3.6 1.1e-08 34.4 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 KFP03115.1 - 1.6e-37 127.6 0.4 1.7e-14 53.8 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP03115.1 - 6e-29 99.4 1.1 2.5e-09 37.0 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP03115.1 - 7.3e-29 96.9 0.2 0.00011 22.0 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFP03115.1 - 7.5e-27 93.2 0.5 6.8e-09 36.0 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) SAM_2 PF07647.12 KFP03115.1 - 1.3e-12 47.3 0.0 2.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP03115.1 - 1.8e-12 47.1 0.0 3.9e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Macoilin PF09726.4 KFP03115.1 - 0.1 10.8 4.1 0.19 9.9 2.9 1.3 1 1 0 1 1 1 0 Transmembrane protein 7tm_2 PF00002.19 KFP03116.1 - 1.2e-72 243.9 17.4 1.5e-72 243.6 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP03116.1 - 8.4e-20 70.5 3.7 1.5e-19 69.7 2.6 1.4 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 KFP03116.1 - 0.0052 15.7 17.2 0.01 14.7 11.9 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Cluap1 PF10234.4 KFP03117.1 - 2.8e-114 380.8 10.5 3.9e-114 380.3 7.3 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 SseC PF04888.7 KFP03117.1 - 0.062 12.6 3.4 0.1 11.9 2.3 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Atg14 PF10186.4 KFP03117.1 - 0.5 9.2 13.1 0.84 8.5 9.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-T PF15511.1 KFP03117.1 - 2.8 7.0 21.4 1.9 7.6 13.5 1.6 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T Pkinase PF00069.20 KFP03118.1 - 1e-52 178.8 0.0 1.2e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03118.1 - 2.4e-30 105.4 0.0 2.7e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP03118.1 - 7.8e-09 34.8 0.0 1.5e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP03118.1 - 0.00063 19.5 0.0 0.21 11.2 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP03118.1 - 0.0022 17.0 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFP03118.1 - 0.0055 15.5 0.1 0.0099 14.7 0.0 1.4 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Xpo1 PF08389.7 KFP03119.1 - 8.5e-29 100.3 19.1 2.6e-27 95.5 0.0 6.7 6 1 0 6 6 6 2 Exportin 1-like protein IBN_N PF03810.14 KFP03119.1 - 5.7e-08 32.5 1.1 7.8e-07 28.9 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain NDK PF00334.14 KFP03120.1 - 2.3e-55 186.0 0.0 2.6e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 KFP03120.1 - 0.061 13.1 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ adh_short_C2 PF13561.1 KFP03121.1 - 9.8e-35 120.4 0.0 1.3e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFP03121.1 - 1.1e-26 93.7 0.4 1.4e-26 93.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP03121.1 - 9.7e-09 35.1 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.16 KFP03121.1 - 0.032 13.4 0.1 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein 3HCDH_N PF02737.13 KFP03121.1 - 0.038 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Septin PF00735.13 KFP03122.1 - 1.3e-89 299.9 0.1 1.5e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFP03122.1 - 1.4e-07 31.4 0.1 2.3e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP03122.1 - 4.2e-06 26.0 0.1 7.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFP03122.1 - 1.2e-05 25.2 2.2 0.00095 19.0 0.6 2.3 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.11 KFP03122.1 - 4.6e-05 22.6 0.1 7.1e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 KFP03122.1 - 0.00033 20.2 0.1 0.00068 19.1 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 KFP03122.1 - 0.0014 18.9 0.8 0.0044 17.3 0.2 1.8 1 1 0 2 2 2 1 ABC transporter Miro PF08477.8 KFP03122.1 - 0.0016 18.8 0.5 0.0034 17.8 0.2 1.7 2 0 0 2 2 1 1 Miro-like protein IIGP PF05049.8 KFP03122.1 - 0.0017 17.2 0.1 0.042 12.6 0.0 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.7 KFP03122.1 - 0.0019 17.4 0.6 0.057 12.5 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP03122.1 - 0.0031 16.9 0.7 0.4 10.1 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFP03122.1 - 0.0046 16.4 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Ras PF00071.17 KFP03122.1 - 0.0065 15.8 0.2 0.015 14.6 0.1 1.6 1 1 0 1 1 1 1 Ras family AAA_32 PF13654.1 KFP03122.1 - 0.0091 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFP03122.1 - 0.021 14.3 0.1 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KFP03122.1 - 0.023 14.6 0.1 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KFP03122.1 - 0.033 14.3 0.1 0.096 12.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFP03122.1 - 0.058 12.8 0.3 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KFP03122.1 - 0.063 12.8 0.2 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFP03122.1 - 0.1 12.7 0.3 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF1542 PF07564.6 KFP03122.1 - 0.12 12.4 0.4 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) IP_trans PF02121.13 KFP03123.1 - 1e-76 257.4 0.2 1.2e-76 257.2 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein TPR_11 PF13414.1 KFP03124.1 - 9.8e-20 69.9 8.4 5.3e-06 25.9 0.0 5.0 2 2 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 KFP03124.1 - 5.9e-16 57.0 11.9 0.0026 17.5 0.0 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFP03124.1 - 1.7e-13 49.5 12.5 0.0069 15.9 0.0 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFP03124.1 - 1.7e-12 47.0 8.4 0.00035 20.4 0.0 5.8 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFP03124.1 - 1.9e-11 43.5 0.1 0.022 15.3 0.0 6.1 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP03124.1 - 7.8e-11 40.9 4.7 0.66 9.8 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFP03124.1 - 2.1e-09 37.7 1.1 0.016 15.9 0.0 5.2 2 2 4 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP03124.1 - 1.1e-07 31.9 12.7 0.0015 18.6 0.3 4.0 2 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KFP03124.1 - 2.3e-07 31.0 4.8 0.0038 17.5 0.1 4.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP03124.1 - 6e-05 22.9 3.3 8.1 6.9 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP03124.1 - 0.0059 16.3 5.9 5.3 7.0 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP03124.1 - 0.01 15.6 5.1 0.11 12.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFP03124.1 - 0.039 14.4 1.2 1.2e+02 3.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.27 KFP03125.1 - 1.7e-61 202.0 54.6 1.8e-08 33.9 0.3 20.5 20 1 0 20 20 20 15 WD domain, G-beta repeat DUF667 PF05018.8 KFP03125.1 - 0.00053 19.2 0.0 0.00089 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Nucleoporin_N PF08801.6 KFP03125.1 - 0.005 15.6 0.1 0.63 8.7 0.0 3.9 4 1 0 4 4 4 1 Nup133 N terminal like Nup160 PF11715.3 KFP03125.1 - 0.015 13.4 3.5 0.093 10.8 0.1 3.7 5 1 1 6 6 6 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KFP03125.1 - 0.046 13.4 0.0 12 5.7 0.0 4.0 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region EF_assoc_2 PF08356.7 KFP03126.1 - 6.5e-35 118.7 0.0 1.5e-34 117.6 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 KFP03126.1 - 5.2e-31 107.6 0.0 6.5e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 KFP03126.1 - 2.7e-26 90.6 0.4 1.1e-25 88.6 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 KFP03126.1 - 7.5e-21 74.1 0.0 8.6e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 Ras family EF-hand_7 PF13499.1 KFP03126.1 - 4.9e-07 29.7 0.1 0.00066 19.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP03126.1 - 1.1e-06 28.0 0.2 0.00014 21.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KFP03126.1 - 4.4e-06 25.6 0.7 0.0019 17.4 0.0 2.5 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 KFP03126.1 - 2.2e-05 24.3 0.0 0.069 13.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFP03126.1 - 5.8e-05 22.9 0.1 0.075 12.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin family EF-hand_8 PF13833.1 KFP03126.1 - 0.00028 20.4 0.2 0.39 10.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP03126.1 - 0.0028 16.9 0.1 0.0061 15.8 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_10 PF14788.1 KFP03126.1 - 0.029 14.0 1.1 0.97 9.1 0.0 2.5 2 0 0 2 2 2 0 EF hand Arf PF00025.16 KFP03126.1 - 0.032 13.4 0.0 0.33 10.1 0.0 2.5 3 1 0 3 3 3 0 ADP-ribosylation factor family SPARC_Ca_bdg PF10591.4 KFP03126.1 - 0.032 14.2 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_14 PF13173.1 KFP03126.1 - 0.044 13.6 0.0 3.7 7.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFP03126.1 - 0.062 13.5 0.0 6 7.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter U-box PF04564.10 KFP03127.1 - 2.9e-31 107.2 0.0 4.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.23 KFP03127.1 - 2.2e-16 58.6 7.0 5.3e-10 38.4 0.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFP03127.1 - 9.5e-14 50.8 3.8 9.5e-14 50.8 2.6 1.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFP03127.1 - 1.3e-12 46.5 6.1 8.1e-06 25.3 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP03127.1 - 1.3e-11 44.2 2.6 1.3e-11 44.2 1.8 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP03127.1 - 7.9e-11 41.9 2.1 1.9e-10 40.7 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFP03127.1 - 1.1e-09 37.3 3.8 0.00027 20.4 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP03127.1 - 1.1e-07 32.3 0.7 2.7e-07 31.0 0.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP03127.1 - 2e-07 31.2 2.5 4.6e-07 30.0 1.7 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFP03127.1 - 5.4e-07 29.3 0.6 0.014 15.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP03127.1 - 1.6e-05 24.6 1.2 5e-05 23.0 0.8 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP03127.1 - 0.00013 21.4 3.1 0.084 12.7 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP03127.1 - 0.00017 21.9 2.8 0.0076 16.7 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP03127.1 - 0.0023 18.2 6.4 1 9.9 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFP03127.1 - 0.01 15.0 2.0 0.06 12.6 0.1 2.4 2 0 0 2 2 2 1 SHNi-TPR Rsc14 PF08586.5 KFP03127.1 - 0.038 14.4 1.6 4.5 7.7 0.0 3.1 1 1 2 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit TPR_10 PF13374.1 KFP03127.1 - 0.16 11.9 1.7 5.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFP03127.1 - 1 9.5 9.8 3.6 7.7 1.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Cupin_8 PF13621.1 KFP03128.1 - 1.3e-08 34.7 1.8 1.9e-08 34.1 1.3 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFP03128.1 - 0.00017 20.9 0.3 0.00025 20.4 0.2 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KFP03128.1 - 0.00065 19.9 0.0 0.0015 18.7 0.0 1.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KFP03128.1 - 0.0019 17.6 0.7 0.013 14.9 0.5 2.0 1 1 0 1 1 1 1 Cupin domain WD40 PF00400.27 KFP03129.1 - 4.5e-28 96.0 5.8 4.2e-11 42.2 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat XPA_C PF05181.7 KFP03129.1 - 0.12 11.9 0.1 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 XPA protein C-terminus LRR_6 PF13516.1 KFP03130.1 - 5e-14 50.7 5.4 0.1 12.7 0.0 8.2 9 1 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 KFP03130.1 - 4.6e-11 42.0 4.6 0.14 11.7 0.0 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP03130.1 - 1e-08 34.7 5.8 0.0012 18.5 0.2 4.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 KFP03130.1 - 1.7e-06 27.2 9.9 2.2 8.8 0.0 7.4 8 0 0 8 8 8 2 Leucine rich repeat LRR_1 PF00560.28 KFP03130.1 - 8.7e-06 25.0 11.3 1.4 9.1 0.0 7.4 6 2 1 7 7 7 2 Leucine Rich Repeat F-box-like PF12937.2 KFP03130.1 - 0.0044 16.7 1.4 0.016 14.9 1.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFP03130.1 - 0.026 14.1 0.1 0.026 14.1 0.1 3.0 3 0 0 3 3 3 0 F-box domain Methyltransf_26 PF13659.1 KFP03132.1 - 6.8e-06 26.1 0.0 8.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP03132.1 - 9.1e-06 26.2 0.0 1.1e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP03132.1 - 0.00053 19.5 0.0 0.00071 19.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP03132.1 - 0.0021 17.8 0.0 0.0025 17.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DUF3417 PF11897.3 KFP03133.1 - 0.016 15.1 3.7 0.31 11.0 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) PyocinActivator PF11112.3 KFP03133.1 - 0.058 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Pyocin activator protein PrtN RVT_2 PF07727.9 KFP03133.1 - 0.13 11.2 1.5 0.22 10.4 0.4 1.8 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF883 PF05957.8 KFP03133.1 - 0.3 11.4 7.7 8.4 6.8 0.0 4.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) ParA PF10609.4 KFP03134.1 - 1e-34 118.2 0.0 2.1e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFP03134.1 - 2.1e-17 63.1 0.0 3.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KFP03134.1 - 2.9e-09 36.3 0.0 9.9e-09 34.6 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 KFP03134.1 - 4.6e-08 32.8 0.0 2e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KFP03134.1 - 1.3e-07 30.9 0.4 2.8e-06 26.6 0.1 2.7 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 KFP03134.1 - 5.1e-07 29.7 0.0 1.8e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 KFP03134.1 - 3.2e-05 22.8 0.1 4.4e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 ArgK protein Fer4_NifH PF00142.13 KFP03134.1 - 6.3e-05 22.2 0.0 0.0035 16.5 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.15 KFP03134.1 - 0.0064 16.1 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 KFP03134.1 - 0.008 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_25 PF13481.1 KFP03134.1 - 0.008 15.6 0.6 0.014 14.8 0.1 1.6 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 KFP03134.1 - 0.0084 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein SRP54 PF00448.17 KFP03134.1 - 0.0093 15.4 0.0 0.046 13.1 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KFP03134.1 - 0.036 14.8 0.2 0.27 12.0 0.4 2.0 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KFP03134.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KFP03134.1 - 0.075 12.2 0.1 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KFP03134.1 - 0.086 12.5 0.2 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 NTPase GFO_IDH_MocA PF01408.17 KFP03134.1 - 0.087 13.3 0.0 0.29 11.6 0.0 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold AAA_30 PF13604.1 KFP03134.1 - 0.13 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFP03134.1 - 0.15 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 KFP03134.1 - 0.21 11.8 0.4 0.28 11.4 0.3 1.4 1 1 0 1 1 1 0 AAA domain SPRY PF00622.23 KFP03135.1 - 2e-17 63.4 0.1 5e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.11 KFP03135.1 - 0.00074 19.3 2.1 0.0018 18.0 1.5 1.7 1 0 0 1 1 1 1 SOCS box PDZ PF00595.19 KFP03136.1 - 9.2e-32 109.0 3.3 6.6e-20 71.0 0.1 2.1 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP03136.1 - 2.4e-08 33.7 1.0 0.00035 20.3 0.1 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_assoc PF10600.4 KFP03136.1 - 0.00027 21.1 1.8 0.00043 20.5 1.2 1.3 1 0 0 1 1 1 1 PDZ-associated domain of NMDA receptors TetM_leader PF08076.6 KFP03136.1 - 0.062 12.8 0.1 16 5.1 0.0 2.4 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide L27_1 PF09058.5 KFP03137.1 - 0.0015 18.3 1.3 0.055 13.3 0.1 2.0 2 0 0 2 2 2 1 L27_1 efb-c PF12199.3 KFP03137.1 - 0.014 15.2 0.3 0.016 15.0 0.2 1.1 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal MitMem_reg PF13012.1 KFP03137.1 - 0.097 12.7 1.0 0.11 12.6 0.7 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Ribosomal_L14e PF01929.12 KFP03137.1 - 0.13 12.6 0.8 0.15 12.4 0.6 1.1 1 0 0 1 1 1 0 Ribosomal protein L14 TBCA PF02970.11 KFP03137.1 - 0.16 12.0 4.3 0.18 11.8 3.0 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF1370 PF07114.6 KFP03138.1 - 9.9e-66 220.5 0.3 1.2e-65 220.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1370) DUF1664 PF07889.7 KFP03139.1 - 0.027 14.2 2.7 0.025 14.3 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Erp_C PF06780.6 KFP03139.1 - 0.038 13.8 12.2 0.038 13.8 8.0 1.3 1 1 0 1 1 1 0 Erp protein C-terminus HR1 PF02185.11 KFP03139.1 - 0.19 11.4 0.4 0.19 11.4 0.3 2.8 2 1 2 4 4 4 0 Hr1 repeat DUF4618 PF15397.1 KFP03139.1 - 0.25 10.6 13.9 0.28 10.4 9.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TMCO5 PF14992.1 KFP03139.1 - 0.41 9.7 11.2 0.55 9.3 7.7 1.3 1 0 0 1 1 1 0 TMCO5 family PKK PF12474.3 KFP03139.1 - 0.61 9.8 14.0 0.79 9.4 2.1 2.1 2 0 0 2 2 2 0 Polo kinase kinase FKBP_N PF01346.13 KFP03139.1 - 0.82 9.7 7.2 1.3 9.0 3.7 1.9 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase WASH-7_C PF14746.1 KFP03139.1 - 1 8.9 5.8 0.24 10.9 0.2 2.0 1 1 1 2 2 2 0 WASH complex subunit 7, C-terminal PTPlike_phytase PF14566.1 KFP03139.1 - 1.2 9.1 5.8 2.1 8.4 4.0 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate Cortex-I_coil PF09304.5 KFP03139.1 - 1.3 9.0 11.7 0.13 12.2 2.4 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF740 PF05340.7 KFP03139.1 - 4.8 5.4 11.1 5.2 5.3 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) ANTH PF07651.11 KFP03140.1 - 7.5e-82 274.1 0.6 1e-81 273.7 0.4 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KFP03140.1 - 2.9e-13 49.7 0.1 5.9e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 ENTH domain EF-1_beta_acid PF10587.4 KFP03140.1 - 0.8 9.9 5.4 1.7 8.8 3.8 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ribosomal_60s PF00428.14 KFP03140.1 - 2.2 8.7 6.0 11 6.4 0.3 2.5 1 1 1 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.27 KFP03141.1 - 3.7e-14 51.9 11.7 3.6e-06 26.6 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 KFP03141.1 - 0.0057 14.8 0.0 0.0092 14.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Lipoprotein_3 PF00938.12 KFP03141.1 - 0.065 13.0 1.1 0.094 12.5 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein DUF775 PF05603.7 KFP03142.1 - 2.2e-46 157.9 0.3 2.8e-46 157.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ANTH PF07651.11 KFP03142.1 - 0.062 11.9 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 ANTH domain Apidaecin PF00807.12 KFP03144.1 - 0.077 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Apidaecin DUF3279 PF11682.3 KFP03144.1 - 0.15 11.6 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) Yae1_N PF09811.4 KFP03145.1 - 2.5e-13 49.2 63.8 0.7 9.4 2.0 11.6 11 1 0 11 11 11 11 Essential protein Yae1, N terminal NTPase_1 PF03266.10 KFP03146.1 - 3 7.5 5.2 14 5.3 0.1 3.1 3 1 0 3 3 3 0 NTPase RRM_6 PF14259.1 KFP03147.1 - 5.5e-07 29.4 0.0 9.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03147.1 - 3.7e-06 26.6 0.1 7.4e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP03147.1 - 0.00023 20.7 0.0 0.00048 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KFP03147.1 - 0.04 14.0 1.6 0.072 13.2 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP03147.1 - 3.3 8.0 4.9 6.4 7.1 3.4 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PAM2 PF07145.10 KFP03148.1 - 6.9e-07 28.3 0.1 6.9e-07 28.3 0.1 1.8 2 0 0 2 2 2 1 Ataxin-2 C-terminal region ATP-synt_ab PF00006.20 KFP03149.1 - 9.8e-45 152.6 0.0 1.3e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFP03149.1 - 1.3e-14 54.5 0.1 2.6e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Homeobox PF00046.24 KFP03150.1 - 1e-12 47.4 1.6 1.2e-12 47.1 1.1 1.1 1 0 0 1 1 1 1 Homeobox domain Ig_2 PF13895.1 KFP03151.1 - 1.2e-51 172.7 13.3 2.8e-12 46.6 0.3 6.2 6 0 0 6 6 6 6 Immunoglobulin domain I-set PF07679.11 KFP03151.1 - 2.2e-40 136.4 0.5 3.5e-08 33.2 0.1 7.7 6 3 0 6 6 6 5 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP03151.1 - 7.6e-28 96.7 19.9 4.2e-08 33.5 0.8 7.0 6 3 0 6 6 6 5 Immunoglobulin domain V-set PF07686.12 KFP03151.1 - 3.1e-23 81.8 11.2 0.0011 18.8 0.7 9.1 4 2 2 6 6 6 6 Immunoglobulin V-set domain ig PF00047.20 KFP03151.1 - 6.1e-21 74.3 8.9 0.0016 18.4 0.2 6.9 6 1 0 6 6 6 5 Immunoglobulin domain C2-set_2 PF08205.7 KFP03151.1 - 6.9e-09 35.4 11.4 2e-05 24.4 0.4 5.5 6 1 0 6 6 6 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFP03151.1 - 7.3e-08 32.3 9.3 0.006 16.5 0.0 5.7 7 1 0 7 7 7 2 Immunoglobulin C1-set domain TfuA PF07812.7 KFP03151.1 - 0.16 11.4 0.0 0.45 9.9 0.0 1.7 1 0 0 1 1 1 0 TfuA-like protein AP-5_subunit_s1 PF15001.1 KFP03152.1 - 1.3e-31 110.0 0.0 1.4e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 TRC8_N PF13705.1 KFP03153.1 - 1.5e-81 274.5 15.6 1.8e-81 274.2 10.8 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain IQ PF00612.22 KFP03153.1 - 0.12 12.0 1.1 0.59 9.9 0.7 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif Orai-1 PF07856.7 KFP03153.1 - 0.14 11.7 8.6 0.057 12.9 4.4 1.5 2 0 0 2 2 2 0 Mediator of CRAC channel activity Peptidase_M14 PF00246.19 KFP03154.1 - 2.7e-78 263.3 0.1 4e-78 262.8 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase F5_F8_type_C PF00754.20 KFP03154.1 - 1.1e-30 106.1 0.4 2.5e-30 104.9 0.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain DUF3999 PF13163.1 KFP03154.1 - 0.056 12.3 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Vps16_N PF04841.8 KFP03155.1 - 2.3e-121 405.1 0.0 2.9e-121 404.8 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KFP03155.1 - 6.9e-110 366.9 0.3 9.5e-110 366.4 0.2 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Iso_dh PF00180.15 KFP03156.1 - 2.7e-73 246.9 0.1 3.3e-73 246.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA_3 PF07726.6 KFP03156.1 - 0.02 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynactin PF12455.3 KFP03157.1 - 5.3e-41 140.3 1.1 5.3e-41 140.3 0.8 4.5 2 1 2 5 5 5 2 Dynein associated protein IncA PF04156.9 KFP03157.1 - 0.00018 21.1 74.9 1.3 8.5 25.5 4.8 1 1 2 3 3 3 3 IncA protein Filament PF00038.16 KFP03157.1 - 0.0085 15.5 81.7 0.42 10.0 18.0 3.6 1 1 0 2 2 2 2 Intermediate filament protein Reo_sigmaC PF04582.7 KFP03157.1 - 0.029 13.5 16.8 0.26 10.4 2.6 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 KFP03157.1 - 0.53 9.5 68.1 0.045 13.0 17.2 3.3 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain WEMBL PF05701.6 KFP03157.1 - 2.2 6.6 89.3 0.041 12.3 22.8 3.3 1 1 2 3 3 3 0 Weak chloroplast movement under blue light CAP_GLY PF01302.20 KFP03158.1 - 6.2e-24 83.4 2.2 7.9e-24 83.1 1.5 1.1 1 0 0 1 1 1 1 CAP-Gly domain adh_short PF00106.20 KFP03159.1 - 7.1e-07 29.2 0.0 7.5e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Neurexophilin PF06312.7 KFP03161.1 - 4.4e-49 166.6 0.0 7.1e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Neurexophilin Filamin PF00630.14 KFP03161.1 - 1.1e-05 25.9 0.0 2.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat PC-Esterase PF13839.1 KFP03161.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.7 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p CD20 PF04103.10 KFP03161.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 CD20-like family Ank PF00023.25 KFP03162.1 - 6.6e-32 107.7 3.0 2.2e-06 27.1 0.1 6.9 6 1 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFP03162.1 - 3.4e-30 104.2 13.0 1.4e-13 51.0 0.3 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP03162.1 - 2.2e-23 82.1 5.2 2.2e-05 24.8 0.0 6.1 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP03162.1 - 1.2e-18 65.2 7.3 0.0028 17.7 0.0 7.4 6 1 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFP03162.1 - 5e-18 64.7 7.7 8.4e-09 35.4 0.2 5.4 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Zona_pellucida PF00100.18 KFP03163.1 - 4.7e-34 118.0 2.1 6.3e-34 117.6 1.5 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Yae1_N PF09811.4 KFP03164.1 - 8.3e-17 60.4 54.1 0.25 10.8 0.7 5.3 1 1 1 2 2 2 1 Essential protein Yae1, N terminal C2-set_2 PF08205.7 KFP03165.1 - 3.3e-27 94.2 6.6 2.7e-20 72.0 0.0 4.5 3 1 1 4 4 4 3 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFP03165.1 - 7.7e-27 93.2 8.2 4.7e-07 29.8 0.1 5.5 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFP03165.1 - 1.5e-17 63.8 15.7 3.2e-06 27.5 0.1 6.2 5 2 1 6 6 6 4 Immunoglobulin domain I-set PF07679.11 KFP03165.1 - 1.7e-15 56.6 16.3 0.0011 18.7 0.1 7.9 5 3 0 6 6 6 5 Immunoglobulin I-set domain V-set PF07686.12 KFP03165.1 - 3.5e-13 49.4 11.5 5.3e-05 23.0 0.0 7.4 5 3 1 6 6 6 3 Immunoglobulin V-set domain ig PF00047.20 KFP03165.1 - 1.7e-12 47.2 14.6 0.0045 17.0 0.1 7.4 6 3 0 6 6 6 4 Immunoglobulin domain C1-set PF07654.10 KFP03165.1 - 3.4e-08 33.3 9.1 0.00044 20.1 0.1 4.6 4 1 0 4 4 4 2 Immunoglobulin C1-set domain DUF4366 PF14283.1 KFP03165.1 - 0.0015 18.0 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Podoplanin PF05808.6 KFP03165.1 - 0.051 13.1 0.2 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 Podoplanin Cbl_N PF02262.11 KFP03166.1 - 7.2e-56 187.4 1.4 1.5e-55 186.4 1.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Cbl_N3 PF02762.9 KFP03166.1 - 1e-51 172.4 0.1 2.5e-51 171.2 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.9 KFP03166.1 - 1.9e-45 152.8 1.4 3.2e-45 152.0 1.0 1.4 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain zf-C3HC4_3 PF13920.1 KFP03166.1 - 2.7e-10 39.7 7.7 5.5e-10 38.7 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP03166.1 - 9.3e-09 35.1 7.4 2.5e-08 33.7 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP03166.1 - 1.2e-08 34.4 7.4 1.2e-08 34.4 5.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP03166.1 - 3.2e-06 26.8 6.8 1e-05 25.2 4.7 2.0 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 KFP03166.1 - 1.3e-05 24.6 5.0 2.9e-05 23.5 3.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 KFP03166.1 - 0.00014 21.5 10.2 0.00036 20.2 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP03166.1 - 0.0085 15.9 8.2 0.025 14.4 5.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2205 PF10224.4 KFP03166.1 - 0.12 11.9 0.2 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) zf-RING_UBOX PF13445.1 KFP03166.1 - 0.43 10.3 7.1 1.7 8.4 4.9 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KFP03166.1 - 5 6.7 18.6 0.052 13.1 6.9 2.3 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF2028 PF09667.5 KFP03167.1 - 4.9e-51 172.8 4.5 4.9e-51 172.8 3.1 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF2028) HMG_box PF00505.14 KFP03167.1 - 2.3e-17 63.0 0.9 7.8e-17 61.3 0.6 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP03167.1 - 1.2e-10 41.6 0.7 4.2e-10 39.8 0.5 2.1 1 0 0 1 1 1 1 HMG-box domain V-set_CD47 PF08204.6 KFP03168.1 - 8.6e-35 119.3 0.0 1.3e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 CD47 immunoglobulin-like domain CD47 PF04549.9 KFP03168.1 - 1.7e-34 119.1 18.1 2.6e-34 118.5 12.5 1.3 1 0 0 1 1 1 1 CD47 transmembrane region V-set PF07686.12 KFP03168.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain IFT57 PF10498.4 KFP03169.1 - 1.3e-133 445.2 3.1 1.5e-133 445.0 2.1 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 MCPsignal PF00015.16 KFP03169.1 - 0.019 14.5 2.1 0.033 13.7 1.2 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BCNT PF07572.7 KFP03169.1 - 0.028 14.3 1.1 0.078 12.9 0.2 2.1 2 0 0 2 2 2 0 Bucentaur or craniofacial development Bacillus_HBL PF05791.6 KFP03169.1 - 0.068 12.5 0.2 0.068 12.5 0.1 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Glyco_transf_25 PF01755.12 KFP03169.1 - 0.11 12.1 3.7 0.16 11.5 0.6 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Mod_r PF07200.8 KFP03169.1 - 0.13 12.1 13.0 0.38 10.6 3.4 2.8 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Prominin PF05478.6 KFP03169.1 - 0.23 8.9 4.6 0.034 11.6 0.3 1.7 2 0 0 2 2 2 0 Prominin DUF4407 PF14362.1 KFP03169.1 - 0.63 8.9 5.1 0.61 8.9 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 KFP03169.1 - 4.5 6.8 19.1 0.91 9.0 3.9 2.5 1 1 1 2 2 2 0 IncA protein Myosin_tail_1 PF01576.14 KFP03170.1 - 0 1111.0 273.5 0 1089.9 144.1 3.0 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.16 KFP03170.1 - 1.7e-266 885.7 0.0 1.7e-266 885.7 0.0 3.5 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 KFP03170.1 - 2.3e-14 52.7 4.4 6.1e-14 51.4 3.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 KFP03170.1 - 0.0014 18.2 47.2 0.0014 18.2 32.7 7.9 1 1 7 8 8 8 4 Intermediate filament protein DUF1664 PF07889.7 KFP03170.1 - 0.0027 17.5 2.4 0.0027 17.5 1.6 12.9 5 2 9 14 14 14 5 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KFP03170.1 - 0.013 14.7 75.3 0.13 11.3 3.0 8.9 2 2 7 10 10 10 0 Reovirus sigma C capsid protein AAA_22 PF13401.1 KFP03170.1 - 0.082 13.0 0.0 0.082 13.0 0.0 5.7 4 3 1 5 5 5 0 AAA domain AAA_19 PF13245.1 KFP03170.1 - 0.11 12.2 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain IQ PF00612.22 KFP03170.1 - 0.12 12.1 1.5 3.2 7.6 0.3 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif SH2 PF00017.19 KFP03171.1 - 3.4e-15 55.5 0.4 4.8e-15 55.1 0.3 1.2 1 0 0 1 1 1 1 SH2 domain Repressor_Mnt PF11423.3 KFP03171.1 - 0.039 13.2 0.2 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Regulatory protein Mnt SIT PF15330.1 KFP03172.1 - 1.5e-26 92.5 0.6 1.5e-26 92.5 0.4 1.5 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT Brr6_like_C_C PF10104.4 KFP03172.1 - 0.092 12.2 0.4 0.14 11.6 0.3 1.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF2663 PF10864.3 KFP03172.1 - 0.093 12.9 0.0 0.9 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) EF-hand_8 PF13833.1 KFP03173.1 - 2.4e-07 30.2 0.1 3.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP03173.1 - 1.2e-06 27.4 0.8 2.8e-06 26.2 0.3 1.9 1 1 1 2 2 2 1 EF hand EF-hand_5 PF13202.1 KFP03173.1 - 2.5e-06 26.5 0.8 5.4e-06 25.5 0.1 1.9 1 1 1 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFP03173.1 - 2.6e-05 24.2 0.1 4.6e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP03173.1 - 3.9e-05 23.1 0.2 0.00015 21.3 0.1 1.9 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KFP03173.1 - 0.13 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region C2-set_2 PF08205.7 KFP03176.1 - 4e-17 61.9 0.0 1.3e-16 60.3 0.0 1.7 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFP03176.1 - 1e-08 35.1 0.1 4.9e-06 26.5 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP03176.1 - 1.2e-08 35.2 0.4 4e-05 24.0 0.2 2.5 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP03176.1 - 0.00054 19.7 0.1 0.034 14.0 0.0 2.6 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 KFP03176.1 - 0.00093 19.2 0.7 0.0088 16.1 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin domain C1-set PF07654.10 KFP03176.1 - 0.037 14.0 0.0 2.9 7.9 0.0 2.4 2 1 0 2 2 2 0 Immunoglobulin C1-set domain V-set PF07686.12 KFP03177.1 - 1.4e-07 31.3 0.2 0.001 18.9 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.20 KFP03177.1 - 0.0043 17.1 0.5 2.8 8.1 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 KFP03177.1 - 0.0078 16.3 0.4 0.15 12.2 0.1 2.3 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFP03177.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP03177.1 - 0.25 11.8 1.3 14 6.2 0.1 2.7 1 1 2 3 3 3 0 Immunoglobulin domain PI-PLC-X PF00388.14 KFP03178.1 - 3.3e-06 26.5 0.0 4.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PH PF00169.24 KFP03179.1 - 2.7e-10 40.3 0.9 9.2e-10 38.6 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFP03179.1 - 0.00012 22.3 0.5 0.00012 22.3 0.4 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFP03179.1 - 0.0011 18.9 0.1 0.0032 17.5 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Abhydrolase_6 PF12697.2 KFP03180.1 - 5.1e-17 62.5 0.0 1e-16 61.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP03180.1 - 4.8e-16 58.8 0.0 6.2e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP03180.1 - 2.6e-11 43.5 0.0 2.3e-09 37.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFP03180.1 - 1.5e-09 37.4 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family UPF0227 PF05728.7 KFP03180.1 - 0.0064 16.2 0.0 0.068 12.8 0.0 2.4 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.8 KFP03180.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.11 KFP03180.1 - 0.029 13.7 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KFP03180.1 - 0.056 13.1 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Vint PF14623.1 KFP03180.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Hint-domain DUF515 PF04415.7 KFP03180.1 - 0.13 10.4 0.2 0.17 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Calponin PF00402.13 KFP03181.1 - 1.7e-13 49.6 3.6 1.7e-13 49.6 2.5 2.4 3 0 0 3 3 3 1 Calponin family repeat CH PF00307.26 KFP03181.1 - 1.7e-13 50.5 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Trypsin PF00089.21 KFP03182.1 - 9.1e-65 218.3 0.3 1.7e-64 217.4 0.2 1.5 1 0 0 1 1 1 1 Trypsin SEA PF01390.15 KFP03182.1 - 5e-26 90.4 0.7 8.5e-26 89.7 0.5 1.4 1 0 0 1 1 1 1 SEA domain Ldl_recept_a PF00057.13 KFP03182.1 - 6.7e-21 73.9 38.1 3.7e-09 36.3 5.2 3.8 2 1 1 3 3 3 3 Low-density lipoprotein receptor domain class A CUB PF00431.15 KFP03182.1 - 1e-12 48.0 0.6 5.3e-06 26.4 0.3 3.1 2 1 0 2 2 2 2 CUB domain Peptidase_S6 PF02395.11 KFP03182.1 - 0.12 10.5 0.1 0.18 9.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin A1 protease V-set PF07686.12 KFP03184.1 - 1.9e-05 24.5 0.0 2.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP03184.1 - 0.00048 19.9 0.0 0.00076 19.2 0.0 1.2 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP03184.1 - 0.0021 18.1 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP03184.1 - 0.0023 18.0 0.3 0.011 15.8 0.2 1.9 1 1 0 1 1 1 1 Immunoglobulin domain Antimicrobial_4 PF08024.6 KFP03184.1 - 0.14 12.0 0.5 0.32 10.8 0.4 1.5 1 0 0 1 1 1 0 Ant antimicrobial peptide I-set PF07679.11 KFP03185.1 - 2.3e-11 43.3 1.0 2.1e-06 27.5 0.1 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFP03185.1 - 5.4e-10 39.1 0.6 1e-09 38.2 0.4 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP03185.1 - 1.6e-09 37.7 3.4 1.6e-06 28.1 0.2 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFP03185.1 - 5.2e-08 32.6 1.8 2.8e-05 23.9 0.2 2.3 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFP03185.1 - 5.2e-06 26.4 10.9 2.2e-05 24.5 1.9 3.5 2 2 0 2 2 2 1 Immunoglobulin domain TMEM154 PF15102.1 KFP03185.1 - 0.013 15.2 0.2 0.023 14.4 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Ig_3 PF13927.1 KFP03185.1 - 0.018 15.5 8.7 0.17 12.3 0.7 3.0 2 2 1 3 3 3 0 Immunoglobulin domain AKAP95 PF04988.7 KFP03186.1 - 0.00031 20.5 1.5 0.00047 19.9 0.8 1.5 1 1 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 KFP03186.1 - 0.0031 17.5 1.7 0.0033 17.4 0.6 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Mut7-C PF01927.11 KFP03186.1 - 0.025 14.5 1.8 0.68 9.8 0.1 2.3 1 1 1 2 2 2 0 Mut7-C RNAse domain Peptidase_S76 PF13611.1 KFP03186.1 - 0.16 12.0 1.1 0.83 9.7 0.2 2.0 1 1 1 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 zf-met PF12874.2 KFP03186.1 - 1.6 9.0 6.0 33 4.8 4.2 2.5 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFP03188.1 - 2.3e-06 27.6 43.0 0.028 14.7 1.4 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type Glyco_hydro_17 PF00332.13 KFP03188.1 - 0.052 12.5 0.1 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 zf-met PF12874.2 KFP03188.1 - 0.065 13.4 15.0 0.2 11.8 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-BED PF02892.10 KFP03188.1 - 2.2 8.1 25.3 0.12 12.2 2.9 3.9 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 KFP03188.1 - 2.4 8.1 21.9 1.3 9.0 2.6 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Yippee-Mis18 PF03226.9 KFP03188.1 - 8.4 6.5 13.7 3 7.9 2.5 3.4 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4518 PF15008.1 KFP03189.1 - 9.4e-103 342.7 0.1 1.1e-102 342.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Ish1 PF10281.4 KFP03189.1 - 0.0032 17.5 0.6 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Choline_kinase PF01633.15 KFP03189.1 - 0.064 12.8 0.4 0.092 12.3 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HeH PF12949.2 KFP03189.1 - 0.11 12.0 0.1 0.39 10.3 0.1 2.0 1 0 0 1 1 1 0 HeH/LEM domain DUF1731 PF08338.6 KFP03190.1 - 9.1e-18 63.4 0.0 1.7e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) NAD_binding_10 PF13460.1 KFP03190.1 - 3.1e-10 40.3 0.0 4.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFP03190.1 - 9.5e-09 35.0 0.0 6.6e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFP03190.1 - 0.078 11.8 0.0 1 8.2 0.0 2.4 3 0 0 3 3 3 0 RmlD substrate binding domain Keratin PF02422.11 KFP03191.1 - 9.1e-36 121.7 12.4 9.9e-36 121.6 8.6 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFP03191.1 - 0.095 12.7 3.1 0.11 12.4 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP03193.1 - 1.8e-28 98.3 12.1 2e-28 98.2 8.4 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.12 KFP03195.1 - 1.9e-11 43.8 0.1 2.1e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP03195.1 - 0.0067 16.5 0.1 0.0074 16.3 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP03195.1 - 0.078 12.8 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.12 KFP03196.1 - 1.4e-10 41.0 0.1 1.6e-10 40.8 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP03196.1 - 0.003 17.6 0.2 0.0034 17.4 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP03196.1 - 0.0045 16.7 0.0 0.0072 16.1 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain C2-set_2 PF08205.7 KFP03196.1 - 0.12 12.2 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 KFP03196.1 - 0.14 12.7 0.5 0.29 11.6 0.3 1.6 1 1 0 1 1 1 0 Immunoglobulin domain Keratin PF02422.11 KFP03197.1 - 9.7e-36 121.6 13.0 1.1e-35 121.5 9.0 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFP03197.1 - 0.15 12.0 3.8 0.19 11.7 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP03199.1 - 9.7e-36 121.6 13.0 1.1e-35 121.5 9.0 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFP03199.1 - 0.15 12.0 3.8 0.19 11.7 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP03201.1 - 9.5e-36 121.6 6.3 1e-35 121.6 4.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP03204.1 - 5.8e-34 115.9 11.9 6.3e-34 115.8 8.2 1.0 1 0 0 1 1 1 1 Keratin V-set PF07686.12 KFP03206.1 - 2.1e-11 43.7 0.1 2.3e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP03206.1 - 0.0057 16.7 0.1 0.0063 16.6 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP03206.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.12 KFP03207.1 - 1.6e-11 44.0 0.1 1.8e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP03207.1 - 0.0019 18.2 0.1 0.0021 18.1 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP03207.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin I-set domain V-set PF07686.12 KFP03210.1 - 1.1e-09 38.1 0.0 1.3e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP03210.1 - 0.00028 20.9 0.1 0.00031 20.8 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP03210.1 - 0.00097 18.9 0.0 0.0016 18.2 0.0 1.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFP03210.1 - 0.12 12.4 0.2 0.78 9.9 0.2 1.9 1 1 0 1 1 1 0 Immunoglobulin domain Keratin PF02422.11 KFP03211.1 - 1.6e-28 98.5 16.6 1.7e-28 98.4 11.5 1.0 1 0 0 1 1 1 1 Keratin MSSP PF03940.8 KFP03211.1 - 0.23 10.8 16.1 0.4 10.1 11.1 1.5 1 0 0 1 1 1 0 Male specific sperm protein Rhomboid PF01694.17 KFP03212.1 - 3.6e-24 85.4 12.9 7.3e-24 84.4 9.0 1.4 1 0 0 1 1 1 1 Rhomboid family PMP22_Claudin PF00822.15 KFP03213.1 - 6.5e-32 110.4 11.6 7.9e-32 110.1 8.0 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP03213.1 - 4e-08 33.1 11.6 4e-08 33.1 8.1 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KFP03213.1 - 0.00028 20.2 8.2 0.0072 15.6 0.5 2.1 1 1 1 2 2 2 2 Clc-like Amastin PF07344.6 KFP03213.1 - 0.0043 16.6 5.0 0.0043 16.6 3.5 2.0 1 1 1 2 2 2 1 Amastin surface glycoprotein VIT1 PF01988.14 KFP03213.1 - 2.5 7.5 7.9 0.57 9.6 0.6 2.3 2 0 0 2 2 2 0 VIT family DUF4231 PF14015.1 KFP03213.1 - 2.7 8.0 9.2 0.18 11.8 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DSPc PF00782.15 KFP03214.1 - 5.7e-33 113.3 0.0 6.3e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Toxin_17 PF08086.6 KFP03214.1 - 0.042 13.9 0.4 0.082 12.9 0.3 1.4 1 0 0 1 1 1 0 Ergtoxin family Y_phosphatase PF00102.22 KFP03214.1 - 0.063 12.6 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Glypican PF01153.14 KFP03215.1 - 3.1e-116 389.2 6.6 3.5e-116 389.0 4.6 1.0 1 0 0 1 1 1 1 Glypican zf-TFIIB PF13453.1 KFP03215.1 - 0.13 11.4 1.5 0.32 10.2 0.1 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger Glypican PF01153.14 KFP03216.1 - 2.6e-195 650.2 5.3 2.9e-195 650.0 3.7 1.0 1 0 0 1 1 1 1 Glypican CBS PF00571.23 KFP03217.1 - 2.5e-37 126.3 2.7 1.7e-10 40.4 0.3 4.3 4 0 0 4 4 4 4 CBS domain Glycos_transf_2 PF00535.21 KFP03218.1 - 1.1e-26 93.5 0.0 1.9e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP03218.1 - 1.1e-20 73.8 2.5 2e-20 73.0 1.7 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFP03218.1 - 7.5e-10 38.9 0.1 5.5e-09 36.1 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFP03218.1 - 3e-07 29.8 0.1 7.3e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP03218.1 - 6.6e-06 25.4 0.0 1.8e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFP03218.1 - 0.0023 18.2 0.0 0.028 14.7 0.0 2.4 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like PHD PF00628.24 KFP03219.1 - 1.2e-36 124.1 138.4 1.4e-09 37.5 4.7 10.2 7 2 3 10 10 10 6 PHD-finger FYRC PF05965.9 KFP03219.1 - 1.9e-25 88.4 0.0 1.2e-24 85.9 0.0 2.5 2 0 0 2 2 2 1 F/Y rich C-terminus SET PF00856.23 KFP03219.1 - 3.1e-24 86.1 0.3 3.1e-24 86.1 0.2 4.3 5 0 0 5 5 5 1 SET domain zf-HC5HC2H PF13771.1 KFP03219.1 - 9.2e-23 80.2 26.8 7.7e-14 51.6 6.6 9.9 4 2 5 9 9 9 2 PHD-like zinc-binding domain FYRN PF05964.9 KFP03219.1 - 4.6e-21 74.0 0.0 9.5e-21 73.0 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H_2 PF13832.1 KFP03219.1 - 4.2e-14 52.4 28.9 6.7e-10 38.9 6.6 9.0 3 2 5 8 8 8 3 PHD-zinc-finger like domain Rad51 PF08423.6 KFP03220.1 - 9.9e-14 50.8 0.0 1.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFP03220.1 - 0.0031 16.9 0.0 0.0085 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 KFP03220.1 - 0.0047 16.0 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 KFP03220.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KFP03220.1 - 0.038 13.6 1.1 0.89 9.1 0.7 2.3 1 1 0 1 1 1 0 NACHT domain Actin PF00022.14 KFP03221.1 - 9.4e-89 297.5 0.0 2.4e-88 296.2 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFP03221.1 - 1.6e-05 23.6 0.0 0.031 12.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Robl_LC7 PF03259.12 KFP03221.1 - 0.013 15.0 0.1 0.034 13.6 0.0 1.6 2 0 0 2 2 2 0 Roadblock/LC7 domain KilA-N PF04383.8 KFP03221.1 - 0.028 14.0 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 KilA-N domain Sec15 PF04091.7 KFP03222.1 - 1.3e-85 287.4 1.2 2.1e-85 286.8 0.9 1.2 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Mitovir_RNA_pol PF05919.6 KFP03222.1 - 0.056 12.3 0.5 0.083 11.8 0.3 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase adh_short PF00106.20 KFP03223.1 - 2.6e-07 30.6 0.2 8.7e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Mtc PF03820.12 KFP03224.1 - 8.2e-94 313.6 0.1 9.2e-94 313.5 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RBD-FIP PF09457.5 KFP03225.1 - 6e-21 73.9 8.3 1.3e-20 72.8 5.7 1.6 1 0 0 1 1 1 1 FIP domain Homeobox PF00046.24 KFP03226.1 - 2e-22 78.5 4.5 2.8e-22 78.0 3.2 1.2 1 0 0 1 1 1 1 Homeobox domain DotA PF11388.3 KFP03226.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phagosome trafficking protein DotA SET PF00856.23 KFP03227.1 - 9.7e-12 45.4 0.5 1.8e-10 41.3 0.4 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KFP03227.1 - 0.00073 19.3 13.6 0.00073 19.3 9.4 2.8 2 2 0 2 2 2 1 MYND finger zf-HIT PF04438.11 KFP03227.1 - 1.6 8.4 13.6 0.054 13.1 3.4 2.6 2 0 0 2 2 2 0 HIT zinc finger PA PF02225.17 KFP03228.1 - 2e-14 53.0 0.0 2.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 PA domain GH97_C PF14509.1 KFP03228.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation MOSC PF03473.12 KFP03229.1 - 6.7e-26 90.3 0.0 7.4e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 MOSC domain Homeobox PF00046.24 KFP03231.1 - 1.1e-09 37.6 0.0 1.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain DSPc PF00782.15 KFP03232.1 - 4.1e-42 142.9 0.5 1.2e-41 141.3 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFP03232.1 - 1.1e-12 48.3 0.0 1.6e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 KFP03232.1 - 6.3e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFP03232.1 - 3.2e-05 23.3 0.1 0.00071 18.9 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KFP03232.1 - 0.0035 16.2 0.0 0.024 13.5 0.0 1.9 2 0 0 2 2 2 1 Initiator tRNA phosphoribosyl transferase TAF1_subA PF14929.1 KFP03233.1 - 9.2e-85 285.1 26.0 3.3e-44 151.2 4.1 3.4 1 1 1 2 2 2 2 TAF RNA Polymerase I subunit A zf-C5HC2 PF02928.11 KFP03233.1 - 7.5 6.7 6.9 33 4.6 0.1 3.3 4 0 0 4 4 4 0 C5HC2 zinc finger SH3_2 PF07653.12 KFP03234.1 - 6.6e-08 31.9 0.0 1.8e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain NPIP PF06409.6 KFP03234.1 - 1.3e-07 30.6 9.3 1.3e-07 30.6 6.4 2.9 2 1 0 2 2 2 1 Nuclear pore complex interacting protein (NPIP) IncA PF04156.9 KFP03234.1 - 7.5e-05 22.4 16.6 7.5e-05 22.4 11.5 7.7 5 2 3 8 8 8 2 IncA protein Reo_sigmaC PF04582.7 KFP03234.1 - 0.58 9.2 22.9 0.13 11.4 3.4 4.0 2 2 1 3 3 3 0 Reovirus sigma C capsid protein UPF0104 PF03706.8 KFP03234.1 - 1.8 7.8 0.0 2.6 7.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Aida_C2 PF14186.1 KFP03235.1 - 4.4e-66 220.7 0.2 5.9e-66 220.3 0.1 1.1 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.5 KFP03235.1 - 9.8e-26 90.0 1.6 1.9e-25 89.1 1.1 1.5 1 0 0 1 1 1 1 Aida N-terminus BRO1 PF03097.13 KFP03236.1 - 3.2e-41 141.3 0.7 3.9e-41 141.0 0.5 1.1 1 0 0 1 1 1 1 BRO1-like domain Patched PF02460.13 KFP03237.1 - 1.5e-22 79.4 29.7 1.3e-15 56.4 6.4 2.8 2 0 0 2 2 2 2 Patched family MMPL PF03176.10 KFP03237.1 - 5.5e-14 51.6 22.8 7.7e-09 34.7 4.9 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.3 KFP03237.1 - 9.2e-11 41.4 16.6 9.2e-11 41.4 11.5 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ERM PF00769.14 KFP03238.1 - 1.8e-72 243.8 38.3 1.8e-72 243.8 26.5 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.5 KFP03238.1 - 7.1e-34 115.8 0.0 2.2e-33 114.3 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFP03238.1 - 3.6e-24 85.3 0.3 3.6e-24 85.3 0.2 3.5 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.5 KFP03238.1 - 2e-19 69.3 1.0 2e-18 66.2 0.1 2.8 2 0 0 2 2 2 1 FERM N-terminal domain DUF3650 PF12368.3 KFP03238.1 - 0.099 12.1 0.2 0.099 12.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) FYVE_2 PF02318.11 KFP03239.1 - 1.8e-18 66.5 12.1 1.8e-18 66.5 8.4 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger C2 PF00168.25 KFP03239.1 - 3.3e-18 65.2 0.1 1.5e-16 59.9 0.0 2.3 2 0 0 2 2 2 1 C2 domain PI3K_C2 PF00792.19 KFP03239.1 - 0.0073 16.0 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Tctex-1 PF03645.8 KFP03240.1 - 1.8e-37 127.2 0.7 2e-37 127.0 0.5 1.0 1 0 0 1 1 1 1 Tctex-1 family MIG-14_Wnt-bd PF06664.7 KFP03241.1 - 6.9e-118 392.8 31.7 6.9e-118 392.8 22.0 1.5 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Tub PF01167.13 KFP03242.1 - 8e-26 90.5 0.6 3e-23 82.1 0.1 3.1 2 1 0 2 2 2 2 Tub family SOCS_box PF07525.11 KFP03242.1 - 2.2e-08 33.8 1.2 7.4e-08 32.1 0.9 2.0 1 0 0 1 1 1 1 SOCS box WD40 PF00400.27 KFP03242.1 - 6.2e-06 25.8 1.2 0.0049 16.7 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat IKI3 PF04762.7 KFP03242.1 - 0.0032 15.3 0.0 0.0063 14.3 0.0 1.3 1 0 0 1 1 1 1 IKI3 family API5 PF05918.6 KFP03242.1 - 0.34 9.3 2.9 0.52 8.7 2.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Tbf5 PF06331.7 KFP03243.1 - 1.1e-29 102.0 0.2 1.2e-29 101.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 PGAP1 PF07819.8 KFP03244.1 - 5.7e-09 35.8 0.0 3.5e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein HEAT_2 PF13646.1 KFP03244.1 - 0.0017 18.6 0.1 1 9.7 0.0 2.6 2 0 0 2 2 2 2 HEAT repeats Abhydrolase_6 PF12697.2 KFP03244.1 - 0.016 15.0 0.1 0.056 13.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Syja_N PF02383.13 KFP03245.1 - 5.3e-75 252.1 0.0 9.2e-75 251.3 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF1866 PF08952.6 KFP03245.1 - 3.3e-54 182.3 0.0 7.7e-54 181.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) Exo_endo_phos PF03372.18 KFP03245.1 - 2.1e-30 106.4 0.1 4e-30 105.5 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_5 PF13893.1 KFP03245.1 - 0.00015 21.5 0.0 0.00042 20.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03245.1 - 0.00018 21.4 0.0 0.00049 20.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP03245.1 - 0.00083 18.9 0.2 0.0024 17.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAR_3_WASP_bdg PF10456.4 KFP03246.1 - 7.8e-110 365.7 0.4 1e-109 365.3 0.3 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 KFP03246.1 - 2.1e-23 82.2 0.2 4.4e-23 81.2 0.2 1.5 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 KFP03246.1 - 1e-09 37.6 0.3 3e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFP03246.1 - 3.3e-09 36.1 0.2 1.3e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFP03246.1 - 2.6e-07 29.9 0.0 5.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 KFP03246.1 - 0.0026 17.0 0.1 0.52 9.5 0.1 2.3 1 1 1 2 2 2 2 Vps5 C terminal like Yae1_N PF09811.4 KFP03247.1 - 2.3e-15 55.8 44.2 1.5e+04 -4.7 30.6 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF1358 PF07096.6 KFP03248.1 - 7.1e-49 164.6 2.1 8.4e-49 164.3 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) DUF3518 PF12031.3 KFP03249.1 - 5.2e-150 497.3 0.1 9.3e-150 496.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3518) ARID PF01388.16 KFP03249.1 - 1e-27 95.8 0.0 2.1e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PV-1 PF06637.6 KFP03249.1 - 3 6.2 3.7 5 5.5 2.5 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) NAD_binding_6 PF08030.7 KFP03252.1 - 6.6e-34 117.0 0.0 4.4e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFP03252.1 - 5.1e-23 80.9 0.0 1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFP03252.1 - 1.2e-22 80.2 1.0 2.5e-22 79.2 0.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFP03252.1 - 3.2e-07 30.3 0.0 5.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFP03252.1 - 0.029 14.9 0.0 0.41 11.2 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain PDGLE PF13190.1 KFP03252.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 PDGLE domain Adeno_E3_CR2 PF02439.10 KFP03252.1 - 9.1 5.9 8.9 40 3.8 6.2 2.1 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RrnaAD PF00398.15 KFP03253.1 - 9e-42 142.9 0.0 1e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KFP03253.1 - 0.0095 15.9 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PMP22_Claudin PF00822.15 KFP03254.1 - 1.1e-27 96.7 9.4 1.3e-27 96.4 6.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP03254.1 - 1.1e-11 44.7 7.1 1.9e-11 43.9 4.9 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 KFP03254.1 - 0.062 12.7 0.1 0.062 12.7 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) CD20 PF04103.10 KFP03254.1 - 0.31 10.9 14.7 0.25 11.2 4.0 3.1 2 1 1 3 3 3 0 CD20-like family DUF4064 PF13273.1 KFP03254.1 - 2.4 8.3 6.6 2.7 8.1 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF998 PF06197.8 KFP03254.1 - 5.2 6.3 10.2 5 6.3 1.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF998) RhoGEF PF00621.15 KFP03255.1 - 3.5e-27 95.4 1.0 1.5e-26 93.4 0.5 2.1 2 0 0 2 2 2 1 RhoGEF domain Frankia_peptide PF14407.1 KFP03255.1 - 0.096 12.4 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PH_9 PF15410.1 KFP03256.1 - 3.9e-07 30.2 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFP03256.1 - 5.6e-07 29.7 0.1 3.9e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 PH domain Mnd1 PF03962.10 KFP03256.1 - 0.0082 15.8 1.3 0.012 15.2 0.9 1.2 1 0 0 1 1 1 1 Mnd1 family DUF4660 PF15559.1 KFP03256.1 - 0.097 12.7 0.7 0.33 11.0 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4660) DUF892 PF05974.7 KFP03256.1 - 0.1 12.3 1.1 0.32 10.7 0.2 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF892) DUF1170 PF06663.8 KFP03257.1 - 8.1e-51 172.6 0.2 1.6e-50 171.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1170) CRIC_ras_sig PF10534.4 KFP03257.1 - 5.6e-41 138.4 0.6 1.5e-40 137.1 0.1 2.0 2 0 0 2 2 2 1 Connector enhancer of kinase suppressor of ras SAM_1 PF00536.25 KFP03257.1 - 3.9e-12 46.1 0.3 8.3e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KFP03257.1 - 1.4e-10 41.2 0.3 2.8e-10 40.3 0.2 1.5 1 0 0 1 1 1 1 PH domain PDZ PF00595.19 KFP03257.1 - 1.4e-09 37.9 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SAM_2 PF07647.12 KFP03257.1 - 2.5e-08 33.6 0.5 5.8e-08 32.4 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_2 PF13180.1 KFP03257.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PH_11 PF15413.1 KFP03257.1 - 0.012 15.8 0.6 0.027 14.7 0.4 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain 7tm_1 PF00001.16 KFP03258.1 - 9.2e-63 211.7 25.2 1.2e-62 211.4 17.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP03258.1 - 7e-09 35.2 15.0 8.8e-09 34.8 10.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Herpes_US9 PF06072.6 KFP03258.1 - 5.5 6.9 10.0 0.1 12.4 0.5 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 RGS PF00615.14 KFP03260.1 - 4.1e-36 123.6 1.1 5.6e-36 123.2 0.8 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4226 PF10774.4 KFP03260.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) F-box PF00646.28 KFP03261.1 - 4.8e-08 32.4 0.1 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain IBR PF01485.16 KFP03261.1 - 9.5e-08 31.8 9.6 2.4e-07 30.5 6.6 1.7 1 0 0 1 1 1 1 IBR domain Hormone_2 PF00123.15 KFP03262.1 - 3.7e-22 77.7 1.0 3.4e-10 39.5 0.2 2.4 2 0 0 2 2 2 2 Peptide hormone Oest_recep PF02159.10 KFP03263.1 - 9.4e-54 181.3 9.1 9.4e-54 181.3 6.3 2.3 2 0 0 2 2 2 1 Oestrogen receptor zf-C4 PF00105.13 KFP03263.1 - 1.2e-31 108.6 13.9 2.2e-31 107.8 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFP03263.1 - 9.1e-29 100.0 1.6 1.5e-28 99.3 1.1 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor ESR1_C PF12743.2 KFP03263.1 - 4e-21 74.2 2.6 4e-21 74.2 1.8 1.9 2 0 0 2 2 2 1 Oestrogen-type nuclear receptor final C-terminal ADIP PF11559.3 KFP03264.1 - 0.011 15.6 90.6 0.061 13.2 6.0 6.0 3 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding DUF89 PF01937.14 KFP03265.1 - 5e-119 397.2 0.2 5.7e-119 397.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CLTH PF10607.4 KFP03265.1 - 0.073 12.7 3.0 2.3 7.8 2.1 2.6 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain DUF155 PF02582.9 KFP03266.1 - 2e-30 105.9 0.9 2e-30 105.9 0.6 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 BTB PF00651.26 KFP03267.1 - 2.2e-19 69.4 0.2 4.6e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP03267.1 - 6.9e-13 48.1 22.3 8e-05 22.7 1.7 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03267.1 - 8e-13 47.9 32.7 0.00052 20.1 1.1 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.2 KFP03267.1 - 2.4e-08 33.9 21.8 0.13 12.4 0.6 4.8 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFP03267.1 - 3.9e-08 33.0 29.2 0.004 17.3 0.9 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP03267.1 - 5.5e-08 32.7 17.4 0.023 14.8 0.1 4.7 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP03267.1 - 0.0044 16.8 22.6 1.7 8.6 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFP03267.1 - 0.026 14.1 19.5 0.25 11.0 0.3 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KFP03267.1 - 0.11 12.6 17.3 4.3 7.5 0.2 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_2 PF03107.11 KFP03267.1 - 3.5 7.8 15.1 6.4 6.9 0.1 4.3 4 0 0 4 4 4 0 C1 domain C1_4 PF07975.7 KFP03267.1 - 3.8 7.6 14.3 4.1 7.4 2.9 3.9 3 1 1 4 4 4 0 TFIIH C1-like domain Ribosomal_L37ae PF01780.14 KFP03267.1 - 7.2 6.5 10.4 17 5.3 0.0 3.6 3 1 1 4 4 4 0 Ribosomal L37ae protein family WSK PF03832.8 KFP03270.1 - 9.1e-14 50.5 12.0 2.1e-12 46.1 2.0 4.2 4 0 0 4 4 4 2 WSK motif NAD_binding_5 PF07994.7 KFP03270.1 - 1.1 8.6 9.8 0.093 12.2 2.5 2.2 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase RhoGEF PF00621.15 KFP03271.1 - 6e-45 153.3 1.4 6e-45 153.3 0.9 2.4 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFP03271.1 - 0.0043 17.2 0.7 0.015 15.4 0.1 2.3 2 0 0 2 2 2 1 PH domain PH_10 PF15411.1 KFP03271.1 - 0.027 14.6 0.2 0.095 12.8 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Nitroreductase PF00881.19 KFP03272.1 - 1.3e-23 83.6 0.0 1.8e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DUF1443 PF07280.6 KFP03272.1 - 0.083 12.4 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) Ldl_recept_a PF00057.13 KFP03273.1 - 2.2e-06 27.4 12.2 2.2e-06 27.4 8.5 1.6 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Big_3_4 PF13754.1 KFP03273.1 - 0.0063 16.8 0.4 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) DUF4625 PF15418.1 KFP03273.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) Phage_tail PF04630.7 KFP03273.1 - 0.065 12.3 0.2 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Phage major tail protein PCMT PF01135.14 KFP03274.1 - 2.4e-81 272.2 0.0 2.7e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KFP03274.1 - 2.3e-08 33.7 0.0 4e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP03274.1 - 3.5e-08 34.0 0.0 5.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP03274.1 - 8.9e-06 26.1 0.0 2.9e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFP03274.1 - 6.6e-05 22.1 0.0 9.1e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KFP03274.1 - 0.00013 21.1 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 KFP03274.1 - 0.00016 21.4 0.0 0.00048 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KFP03274.1 - 0.00024 20.6 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KFP03274.1 - 0.0012 18.8 0.0 0.0074 16.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP03274.1 - 0.0028 17.9 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP03274.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 KFP03274.1 - 0.015 15.2 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 KFP03274.1 - 0.047 12.7 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 KFP03274.1 - 0.053 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_32 PF13679.1 KFP03274.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 KFP03275.1 - 1e-11 44.2 8.4 0.00061 19.5 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat CPSF_A PF03178.10 KFP03275.1 - 7.9e-05 21.8 0.1 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Hira PF07569.6 KFP03275.1 - 0.06 12.5 0.1 8.4 5.5 0.0 2.8 3 1 1 4 4 4 0 TUP1-like enhancer of split BBS2_Mid PF14783.1 KFP03275.1 - 0.096 12.4 0.2 1.4 8.7 0.0 2.5 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 KFP03276.1 - 4.4e-58 196.4 1.9 2.7e-38 131.5 0.0 3.3 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03276.1 - 3.1e-28 98.5 0.0 2.3e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase UBA PF00627.26 KFP03276.1 - 3.3e-07 29.9 1.0 1.1e-06 28.3 0.2 2.3 3 0 0 3 3 3 1 UBA/TS-N domain Kinase-like PF14531.1 KFP03276.1 - 0.00067 18.6 0.1 0.0025 16.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP03276.1 - 0.0028 17.4 0.4 0.017 14.8 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 KFP03276.1 - 0.02 15.3 1.0 0.02 15.3 0.7 2.3 2 0 0 2 2 1 0 Protein kinase C terminal domain UBA_3 PF09288.5 KFP03276.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Pox_ser-thr_kin PF05445.6 KFP03276.1 - 0.043 12.6 0.1 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YjcZ PF13990.1 KFP03276.1 - 0.045 12.8 0.5 0.079 12.0 0.4 1.3 1 0 0 1 1 1 0 YjcZ-like protein DUF2015 PF09435.5 KFP03276.1 - 0.083 12.6 0.4 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) Seadorna_VP7 PF07387.6 KFP03276.1 - 0.21 10.3 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AAA PF00004.24 KFP03277.1 - 7.1e-40 136.2 0.0 1.4e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFP03277.1 - 9.5e-08 31.8 0.0 2.5e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 KFP03277.1 - 5.3e-06 26.4 0.1 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KFP03277.1 - 1.2e-05 25.1 0.0 4.3e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KFP03277.1 - 1.6e-05 24.1 0.0 4.8e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFP03277.1 - 0.00046 20.3 0.3 0.004 17.2 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFP03277.1 - 0.00065 19.4 0.4 0.0032 17.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFP03277.1 - 0.001 17.8 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 KFP03277.1 - 0.0011 18.5 0.5 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFP03277.1 - 0.0012 18.3 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KFP03277.1 - 0.0013 19.5 0.1 0.0049 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFP03277.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFP03277.1 - 0.0019 18.2 0.0 0.0044 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFP03277.1 - 0.002 18.0 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFP03277.1 - 0.0027 16.9 0.0 0.0061 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TPR_8 PF13181.1 KFP03277.1 - 0.0048 16.5 0.2 0.024 14.3 0.2 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat KaiC PF06745.8 KFP03277.1 - 0.0062 15.6 0.5 0.98 8.4 0.1 2.7 2 1 1 3 3 2 1 KaiC PhoH PF02562.11 KFP03277.1 - 0.0096 15.1 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Zeta_toxin PF06414.7 KFP03277.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KFP03277.1 - 0.049 13.2 0.1 0.26 10.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_18 PF13238.1 KFP03277.1 - 0.053 13.8 3.5 0.16 12.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.22 KFP03277.1 - 0.053 13.8 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 KFP03277.1 - 0.055 13.0 1.4 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFP03277.1 - 0.058 12.7 0.9 0.79 9.0 0.2 2.7 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 KFP03277.1 - 0.058 13.5 0.8 0.14 12.3 0.0 2.2 2 1 0 2 2 1 0 RNA helicase AAA_28 PF13521.1 KFP03277.1 - 0.064 13.2 0.1 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 KFP03277.1 - 0.075 12.4 1.8 0.29 10.5 0.0 2.7 3 0 0 3 3 3 0 Guanylate kinase Sigma54_activ_2 PF14532.1 KFP03277.1 - 0.094 12.7 0.0 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain FluMu_gp41 PF10109.4 KFP03277.1 - 0.12 12.3 0.1 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 TPR_1 PF00515.23 KFP03277.1 - 0.15 11.7 0.2 0.49 10.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Sigma54_activat PF00158.21 KFP03277.1 - 0.15 11.5 0.0 0.52 9.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain TPR_2 PF07719.12 KFP03277.1 - 0.31 11.0 1.6 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Yae1_N PF09811.4 KFP03279.1 - 4.6e-13 48.4 34.7 19 4.8 24.0 3.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Pro_isomerase PF00160.16 KFP03280.1 - 2.5e-31 108.9 0.3 6.6e-31 107.6 0.2 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KFP03280.1 - 4.4e-18 64.6 0.0 9.6e-18 63.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03280.1 - 4.9e-12 45.6 0.0 9.7e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03280.1 - 4.5e-09 36.0 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_Zc3h12a PF11977.3 KFP03281.1 - 1.3e-60 203.7 0.0 1.9e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH PF00642.19 KFP03281.1 - 0.0031 17.1 5.5 0.0083 15.7 2.6 2.4 1 1 1 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFP03281.1 - 0.082 12.9 9.6 0.18 11.8 6.7 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Omega-toxin PF06357.6 KFP03281.1 - 0.31 10.6 3.7 0.64 9.6 2.5 1.5 1 0 0 1 1 1 0 Omega-atracotoxin CUE PF02845.11 KFP03282.1 - 4.2e-09 35.7 0.2 7.6e-09 34.8 0.2 1.4 1 0 0 1 1 1 1 CUE domain zf-RanBP PF00641.13 KFP03282.1 - 1.2e-05 24.3 2.0 2.8e-05 23.1 1.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DivIC PF04977.10 KFP03282.1 - 0.054 12.9 3.2 0.34 10.4 1.9 2.1 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KFP03282.1 - 0.44 10.1 5.3 0.75 9.3 3.6 1.3 1 0 0 1 1 1 0 IncA protein 7tm_2 PF00002.19 KFP03283.1 - 5.4e-78 261.4 19.8 7e-78 261.0 13.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP03283.1 - 3.5e-17 62.1 8.1 7.1e-17 61.1 5.6 1.6 1 0 0 1 1 1 1 Hormone receptor domain PID PF00640.18 KFP03284.1 - 2.4e-33 115.0 0.4 3.6e-33 114.5 0.2 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFP03284.1 - 9.2e-12 45.0 0.3 1.6e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 KFP03284.1 - 2.4e-05 24.0 0.1 3.3e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF3373 PF11853.3 KFP03284.1 - 0.00098 17.7 0.2 0.0014 17.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) DivIC PF04977.10 KFP03284.1 - 0.0012 18.2 4.6 0.0022 17.4 3.2 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.10 KFP03284.1 - 0.0014 18.4 4.8 0.003 17.3 3.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.13 KFP03284.1 - 0.0037 17.1 1.2 0.0098 15.8 0.8 1.7 1 0 0 1 1 1 1 TSC-22/dip/bun family Ax_dynein_light PF10211.4 KFP03284.1 - 0.0037 17.1 0.3 0.0063 16.3 0.2 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain Herpes_BLRF2 PF05812.7 KFP03284.1 - 0.0088 15.8 1.3 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 KFP03284.1 - 0.0095 15.8 1.7 0.016 15.1 1.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor Spc24 PF08286.6 KFP03284.1 - 0.01 15.5 0.3 0.021 14.5 0.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ATG16 PF08614.6 KFP03284.1 - 0.011 15.5 1.3 0.018 14.8 0.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 KFP03284.1 - 0.016 15.1 1.1 0.022 14.6 0.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Leu_zip PF15294.1 KFP03284.1 - 0.017 14.2 0.8 0.027 13.5 0.5 1.2 1 0 0 1 1 1 0 Leucine zipper DUF972 PF06156.8 KFP03284.1 - 0.02 15.2 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Striatin PF08232.7 KFP03284.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Striatin family Herpes_UL6 PF01763.11 KFP03284.1 - 0.026 12.7 0.0 0.041 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like ORF6C PF10552.4 KFP03284.1 - 0.03 14.0 0.6 0.073 12.8 0.4 1.6 1 0 0 1 1 1 0 ORF6C domain IncA PF04156.9 KFP03284.1 - 0.031 13.8 0.4 0.043 13.4 0.3 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KFP03284.1 - 0.035 13.9 5.0 0.086 12.6 3.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nnf1 PF03980.9 KFP03284.1 - 0.043 13.8 3.0 0.043 13.8 2.1 1.6 2 0 0 2 2 1 0 Nnf1 Med4 PF10018.4 KFP03284.1 - 0.045 13.1 0.2 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Prefoldin_2 PF01920.15 KFP03284.1 - 0.062 13.0 2.8 0.13 12.0 1.9 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF904 PF06005.7 KFP03284.1 - 0.068 13.4 3.6 0.14 12.4 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Pox_A_type_inc PF04508.7 KFP03284.1 - 0.36 10.7 2.3 0.74 9.7 0.3 2.3 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DUF4315 PF14193.1 KFP03284.1 - 1.6 8.7 5.4 0.54 10.2 1.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4315) M PF02370.11 KFP03284.1 - 9.2 7.0 6.7 6.9 7.4 2.5 2.5 2 1 1 3 3 2 0 M protein repeat COLFI PF01410.13 KFP03285.1 - 7.7e-52 175.8 0.0 8.4e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain COLFI PF01410.13 KFP03286.1 - 6.2e-51 172.8 0.1 6.8e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain WD40 PF00400.27 KFP03287.1 - 9.5e-19 66.5 23.0 5.5e-05 22.8 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat FPN1 PF06963.7 KFP03288.1 - 2.7e-182 605.9 13.9 3.1e-182 605.7 9.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF347 PF03988.7 KFP03288.1 - 0.045 13.6 0.1 0.045 13.6 0.1 4.2 3 2 1 4 4 4 0 Repeat of Unknown Function (DUF347) Peptidase_M22 PF00814.20 KFP03289.1 - 9.9e-55 185.8 0.7 1.1e-54 185.7 0.5 1.0 1 0 0 1 1 1 1 Glycoprotease family ORMDL PF04061.9 KFP03290.1 - 1.4e-53 180.0 2.1 1.6e-53 179.9 1.5 1.0 1 0 0 1 1 1 1 ORMDL family 7tm_3 PF00003.17 KFP03290.1 - 0.047 13.0 0.2 0.047 13.0 0.1 1.6 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DNA_mis_repair PF01119.14 KFP03291.1 - 1.2e-24 86.0 0.1 1.8e-23 82.2 0.0 2.6 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HMG_box PF00505.14 KFP03291.1 - 2.3e-15 56.5 3.5 2.3e-15 56.5 2.4 2.3 3 0 0 3 3 3 1 HMG (high mobility group) box HATPase_c_3 PF13589.1 KFP03291.1 - 8.9e-14 51.3 0.2 2.5e-13 49.8 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box_2 PF09011.5 KFP03291.1 - 7.8e-12 45.3 3.0 1.9e-11 44.1 2.0 1.6 1 0 0 1 1 1 1 HMG-box domain HATPase_c PF02518.21 KFP03291.1 - 3e-11 43.0 0.1 7.3e-11 41.7 0.1 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HMG_box_5 PF14887.1 KFP03291.1 - 0.00032 20.4 2.3 0.00073 19.2 1.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box 5 IL5 PF02025.10 KFP03291.1 - 0.014 15.4 0.6 0.82 9.7 0.0 2.8 2 0 0 2 2 2 0 Interleukin 5 TGFb_propeptide PF00688.13 KFP03292.1 - 2.8e-48 164.3 0.0 3.7e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFP03292.1 - 2.8e-28 98.2 1.2 7.7e-28 96.8 0.8 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain ECH_C PF13766.1 KFP03293.1 - 1.8e-44 150.6 0.0 3.9e-44 149.5 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KFP03293.1 - 1.7e-34 119.0 0.0 5.1e-33 114.2 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Thioredox_DsbH PF03190.10 KFP03293.1 - 0.037 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 MFS_1 PF07690.11 KFP03294.1 - 1.8e-30 105.8 24.4 3.9e-17 62.0 8.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 KFP03294.1 - 1.8e-16 59.7 3.9 1.8e-16 59.7 2.7 2.9 4 0 0 4 4 4 1 MFS_1 like family MFS_2 PF13347.1 KFP03294.1 - 6.3e-10 38.0 17.6 4.2e-08 31.9 9.2 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein Nuc_H_symport PF03825.11 KFP03294.1 - 8.4e-08 31.3 7.0 8.4e-08 31.3 4.8 3.6 3 1 0 3 3 3 1 Nucleoside H+ symporter LacY_symp PF01306.14 KFP03294.1 - 1.3e-06 27.2 18.7 0.003 16.1 3.6 3.2 3 0 0 3 3 3 3 LacY proton/sugar symporter MFS_3 PF05977.8 KFP03294.1 - 9.5e-05 20.6 1.4 0.00049 18.3 0.4 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector ATG22 PF11700.3 KFP03294.1 - 0.00072 18.1 18.8 0.18 10.2 0.2 3.1 3 0 0 3 3 3 3 Vacuole effluxer Atg22 like DUF3671 PF12420.3 KFP03294.1 - 0.12 12.4 0.9 0.72 9.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function OppC_N PF12911.2 KFP03294.1 - 1.1 8.6 12.8 1.1 8.7 0.0 3.9 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF2215 PF10225.4 KFP03295.1 - 1.2e-77 260.8 3.3 1.4e-77 260.4 2.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) NCD2 PF04905.8 KFP03296.1 - 4.3e-78 260.7 1.7 6.9e-78 260.1 1.2 1.3 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) Nab1 PF04902.7 KFP03296.1 - 3.5e-63 212.0 0.5 1.4e-62 210.0 0.3 2.1 1 1 0 1 1 1 1 Conserved region in Nab1 NCD1 PF04904.8 KFP03296.1 - 8.1e-46 153.6 0.1 1.4e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) tRNA-synt_1b PF00579.20 KFP03296.1 - 0.19 10.8 0.6 2.9 6.9 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Ribosomal_S3_C PF00189.15 KFP03297.1 - 2.2e-16 59.8 0.1 4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KFP03297.1 - 5.8e-12 44.9 0.1 9.2e-12 44.3 0.1 1.3 1 0 0 1 1 1 1 KH domain SH3_1 PF00018.23 KFP03298.1 - 1.8e-26 91.2 1.5 1.1e-12 47.0 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFP03298.1 - 7.1e-25 86.3 1.5 6.6e-14 51.2 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KFP03298.1 - 2.2e-21 75.0 0.2 8.4e-11 41.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 KFP03298.1 - 4.4e-06 26.7 6.2 8.4e-06 25.8 0.2 3.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.6 KFP03298.1 - 0.0035 17.4 0.5 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain 3H PF02829.9 KFP03298.1 - 0.037 14.0 1.9 0.14 12.1 0.1 2.8 2 2 1 3 3 3 0 3H domain Vac14_Fab1_bd PF12755.2 KFP03298.1 - 0.081 13.3 1.0 0.28 11.6 0.2 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region H-kinase_dim PF02895.9 KFP03298.1 - 0.11 12.8 3.8 5.6 7.3 0.0 3.8 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain CENP-Q PF13094.1 KFP03298.1 - 1.4 8.9 16.7 2.2 8.2 3.2 2.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase PF00069.20 KFP03300.1 - 1.6e-43 148.7 0.0 1.9e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03300.1 - 3.9e-27 94.9 0.0 4.7e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP03300.1 - 5.7e-06 25.5 0.0 7.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP03300.1 - 6.3e-05 22.8 0.6 0.085 12.5 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP03300.1 - 0.00014 21.0 0.2 0.00019 20.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_35 PF01301.14 KFP03301.1 - 4.7e-103 344.8 0.0 5.9e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 KFP03301.1 - 9.6e-10 38.1 0.0 1.1e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 KFP03301.1 - 2e-08 34.4 0.2 2e-08 34.4 0.1 2.4 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Ank_5 PF13857.1 KFP03302.1 - 3.9e-09 36.4 1.1 2.1e-07 30.9 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFP03302.1 - 8.2e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP03302.1 - 3.3e-08 32.9 0.2 8.3e-07 28.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KFP03302.1 - 6.2e-07 29.0 0.0 6.4e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KFP03302.1 - 9.5e-07 29.1 0.0 0.00045 20.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-FCS PF06467.9 KFP03302.1 - 0.0078 15.8 9.4 0.82 9.3 0.1 3.1 2 1 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif Rrp15p PF07890.7 KFP03302.1 - 4.7 7.2 14.7 2.7 8.0 1.2 2.5 2 0 0 2 2 2 0 Rrp15p APG9 PF04109.11 KFP03303.1 - 1.9e-135 451.5 1.0 2.6e-135 451.0 0.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 EMP24_GP25L PF01105.19 KFP03303.1 - 0.071 12.8 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ABC_tran PF00005.22 KFP03304.1 - 7.6e-35 120.1 0.0 1.3e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KFP03304.1 - 2e-29 102.8 12.6 2.9e-29 102.3 8.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KFP03304.1 - 7.3e-07 28.6 0.2 5.6e-05 22.4 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFP03304.1 - 1.2e-05 25.4 0.1 0.0016 18.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFP03304.1 - 0.00012 22.1 0.2 0.00026 21.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFP03304.1 - 0.00048 19.3 0.0 0.00092 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFP03304.1 - 0.00099 18.5 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFP03304.1 - 0.0013 18.8 0.1 0.0093 16.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFP03304.1 - 0.0032 18.2 0.0 0.0071 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFP03304.1 - 0.0078 16.4 0.0 0.12 12.5 0.0 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFP03304.1 - 0.01 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFP03304.1 - 0.011 15.2 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 KFP03304.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 KFP03304.1 - 0.017 15.0 0.3 0.19 11.6 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KFP03304.1 - 0.026 14.2 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KFP03304.1 - 0.056 13.1 0.1 0.33 10.6 0.0 2.3 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Acyl-CoA_dh_1 PF00441.19 KFP03304.1 - 0.077 13.0 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF815 PF05673.8 KFP03304.1 - 0.081 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFP03304.1 - 0.1 12.4 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFP03304.1 - 0.11 11.8 0.2 0.96 8.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KFP03304.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-AN1 PF01428.11 KFP03305.1 - 5.7e-21 74.1 24.8 8.2e-13 47.9 6.1 2.9 4 0 0 4 4 4 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KFP03305.1 - 0.042 14.0 16.4 0.46 10.7 1.4 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-C3HC PF07967.8 KFP03305.1 - 0.41 10.4 8.2 3.2 7.5 1.3 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like zinc_ribbon_4 PF13717.1 KFP03305.1 - 0.97 9.1 11.8 0.69 9.6 1.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 KFP03305.1 - 1.3 8.8 24.1 15 5.5 2.2 3.4 1 1 1 2 2 2 0 IBR domain zinc_ribbon_5 PF13719.1 KFP03305.1 - 2 8.0 11.7 0.99 9.0 1.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain GFA PF04828.9 KFP03305.1 - 4.9 7.1 9.8 0.32 10.9 0.7 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Reticulon PF02453.12 KFP03306.1 - 0.00037 20.1 0.1 0.00068 19.2 0.1 1.4 1 0 0 1 1 1 1 Reticulon Abi PF02517.11 KFP03306.1 - 0.1 12.7 0.7 0.24 11.5 0.5 1.6 1 0 0 1 1 1 0 CAAX protease self-immunity Cyclin PF08613.6 KFP03307.1 - 6.4e-11 42.8 0.0 8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFP03307.1 - 9.7e-06 25.1 0.1 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Xan_ur_permease PF00860.15 KFP03308.1 - 5.9e-63 212.6 23.6 7.5e-63 212.3 16.4 1.1 1 0 0 1 1 1 1 Permease family XLF PF09302.6 KFP03309.1 - 2.6e-37 128.2 0.0 4.9e-37 127.3 0.0 1.5 2 0 0 2 2 2 1 XLF (XRCC4-like factor) Hint PF01079.15 KFP03310.1 - 4.2e-60 202.6 0.0 2.3e-45 154.4 0.0 2.1 1 1 1 2 2 2 2 Hint module HH_signal PF01085.13 KFP03310.1 - 3.8e-55 185.8 0.6 5e-55 185.4 0.4 1.2 1 0 0 1 1 1 1 Hedgehog amino-terminal signalling domain Peptidase_M15_3 PF08291.6 KFP03310.1 - 0.00089 19.0 0.1 0.0014 18.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase M15 Homeobox PF00046.24 KFP03311.1 - 1.1e-22 79.3 7.1 1.7e-22 78.7 4.9 1.3 1 0 0 1 1 1 1 Homeobox domain QLQ PF08880.6 KFP03311.1 - 0.0027 17.0 0.2 0.005 16.2 0.2 1.4 1 0 0 1 1 1 1 QLQ Motile_Sperm PF00635.21 KFP03312.1 - 9.9e-16 57.3 0.0 0.059 13.0 0.0 8.2 8 0 0 8 8 8 4 MSP (Major sperm protein) domain PapD-like PF14874.1 KFP03312.1 - 1.5e-05 24.8 0.8 3.4 7.6 0.0 5.7 6 0 0 6 6 6 2 Flagellar-associated PapD-like MIP-T3 PF10243.4 KFP03312.1 - 0.4 9.0 0.7 0.65 8.3 0.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TRAPPC9-Trs120 PF08626.6 KFP03312.1 - 0.49 7.6 0.4 1.3 6.2 0.0 1.7 2 0 0 2 2 2 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Crystall PF00030.14 KFP03313.1 - 4.4e-56 186.7 5.8 1.7e-27 95.0 0.6 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFP03313.1 - 0.0008 19.0 2.5 0.0025 17.4 0.5 2.7 2 1 0 2 2 2 1 Beta/Gamma crystallin Ets PF00178.17 KFP03314.1 - 7.5e-40 134.9 0.9 1.1e-39 134.4 0.6 1.2 1 0 0 1 1 1 1 Ets-domain wnt PF00110.14 KFP03315.1 - 8.1e-122 406.2 20.8 9.1e-122 406.0 14.4 1.0 1 0 0 1 1 1 1 wnt family TTL PF03133.10 KFP03316.1 - 1.9e-101 338.8 0.1 2.9e-101 338.2 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KFP03316.1 - 8.5e-06 24.7 0.2 0.00041 19.2 0.0 2.9 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KFP03316.1 - 0.022 14.4 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFP03316.1 - 0.048 12.4 0.0 5.7 5.5 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KFP03316.1 - 0.063 13.1 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain DUF1639 PF07797.9 KFP03316.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Pkinase PF00069.20 KFP03317.1 - 1.9e-75 253.3 0.0 2.9e-75 252.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03317.1 - 2.9e-42 144.5 0.0 4.7e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 KFP03317.1 - 1e-10 40.7 11.2 0.0092 15.9 0.1 7.5 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KFP03317.1 - 6e-10 39.2 5.5 2.2e-07 31.0 1.5 4.1 3 1 1 4 4 2 2 HEAT repeats Arm PF00514.18 KFP03317.1 - 1.3e-07 31.1 8.7 0.00019 21.1 0.2 5.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KFP03317.1 - 1.4e-05 25.4 13.3 0.065 13.7 0.1 6.3 6 1 1 7 7 6 2 HEAT-like repeat Kinase-like PF14531.1 KFP03317.1 - 0.00084 18.3 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP03317.1 - 0.0025 17.5 3.2 0.026 14.2 0.1 3.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Adaptin_N PF01602.15 KFP03317.1 - 0.023 13.0 0.1 0.11 10.8 0.0 1.9 2 0 0 2 2 2 0 Adaptin N terminal region YrbL-PhoP_reg PF10707.4 KFP03317.1 - 0.03 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HEAT_PBS PF03130.11 KFP03317.1 - 0.046 14.2 3.7 1.7 9.3 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RIO1 PF01163.17 KFP03317.1 - 0.11 11.8 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 KFP03317.1 - 0.15 10.8 0.1 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RWD PF05773.17 KFP03318.1 - 5.3e-17 61.7 0.1 9.9e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KFP03318.1 - 1.5e-13 50.2 4.7 2.8e-13 49.4 3.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFP03318.1 - 7.4e-05 22.4 7.2 0.00019 21.1 5.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFP03318.1 - 0.00036 20.4 3.6 0.0014 18.6 2.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP03318.1 - 0.0078 15.8 5.0 0.078 12.6 3.8 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP03318.1 - 0.016 14.8 3.3 0.037 13.6 2.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP03318.1 - 0.12 12.4 9.5 0.24 11.5 4.6 2.6 2 1 1 3 3 3 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFP03318.1 - 0.18 11.6 4.9 0.32 10.8 1.1 2.3 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger BCS1_N PF08740.6 KFP03319.1 - 1.5e-49 168.1 1.3 3.6e-49 166.9 0.9 1.6 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KFP03319.1 - 1.7e-20 73.5 0.0 2.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFP03319.1 - 0.00023 21.9 0.0 0.00075 20.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KFP03319.1 - 0.00087 19.4 0.0 0.002 18.2 0.0 1.7 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 KFP03319.1 - 0.002 17.5 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFP03319.1 - 0.0021 17.0 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 KFP03319.1 - 0.0022 18.0 0.1 0.0053 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KFP03319.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KFP03319.1 - 0.0063 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 KFP03319.1 - 0.011 15.8 0.0 0.087 12.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 KFP03319.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KFP03319.1 - 0.02 14.4 0.0 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.10 KFP03319.1 - 0.028 13.0 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KFP03319.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFP03319.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 KFP03319.1 - 0.099 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 KFP03319.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.6 KFP03319.1 - 0.14 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Zeta_toxin PF06414.7 KFP03319.1 - 0.14 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 KFP03319.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KFP03319.1 - 0.18 11.3 0.1 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KFP03319.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rcd1 PF04078.8 KFP03320.1 - 1.1e-138 460.3 0.4 1.3e-138 460.1 0.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OmdA PF13376.1 KFP03320.1 - 0.18 11.4 0.4 3.6 7.2 0.0 2.7 3 1 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated UCH PF00443.24 KFP03321.1 - 1.8e-62 210.8 15.4 3.1e-62 210.1 10.7 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP03321.1 - 2e-21 76.7 10.3 4.1e-16 59.2 2.8 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.15 KFP03321.1 - 3.4e-07 29.2 22.5 0.0012 18.1 0.2 3.9 3 0 0 3 3 3 3 Ubiquitin interaction motif Elongin_A PF06881.6 KFP03321.1 - 0.071 13.4 6.1 0.31 11.4 4.2 2.1 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Gelsolin PF00626.17 KFP03322.1 - 2.5e-104 341.0 0.1 3.1e-19 68.4 0.0 6.3 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.14 KFP03322.1 - 1.2e-16 60.0 0.8 2.6e-16 58.9 0.5 1.6 1 0 0 1 1 1 1 Villin headpiece domain NIF PF03031.13 KFP03323.1 - 1.5e-48 164.5 0.0 1.8e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2608 PF11019.3 KFP03323.1 - 0.12 11.3 0.0 1.7 7.5 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2608) Nramp PF01566.13 KFP03324.1 - 4.6e-112 374.3 14.4 4.6e-112 374.3 10.0 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Lactamase_B PF00753.22 KFP03326.1 - 1.3e-09 38.0 0.0 3.3e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Bax1-I PF01027.15 KFP03327.1 - 7.6e-26 90.9 27.5 2.2e-25 89.4 19.1 1.6 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BPD_transp_2 PF02653.11 KFP03327.1 - 0.089 11.7 14.5 0.16 10.8 10.0 1.5 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Claudin_2 PF13903.1 KFP03327.1 - 0.41 10.3 8.6 0.1 12.2 0.5 2.4 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction LRRC37AB_C PF14914.1 KFP03327.1 - 0.84 9.0 3.2 0.42 10.0 0.5 1.7 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF4231 PF14015.1 KFP03327.1 - 2.5 8.1 7.2 41 4.2 4.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) WD40 PF00400.27 KFP03328.1 - 1.4e-37 126.2 12.1 2.7e-06 27.0 0.2 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KFP03328.1 - 8.6e-08 32.1 0.3 0.0091 15.7 0.1 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFP03328.1 - 2.3e-05 22.7 0.2 0.067 11.3 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFP03328.1 - 0.0014 17.4 0.0 0.033 12.9 0.0 2.4 1 1 1 2 2 2 1 Nup133 N terminal like PQQ_2 PF13360.1 KFP03328.1 - 0.0016 17.9 0.7 0.13 11.7 0.5 3.2 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 KFP03328.1 - 0.0035 16.7 3.5 0.88 9.2 0.0 4.2 4 0 0 4 4 4 1 PQQ enzyme repeat Apc4_WD40 PF12894.2 KFP03328.1 - 0.063 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain P34-Arc PF04045.9 KFP03329.1 - 9.5e-98 326.2 2.1 1.1e-97 326.0 1.5 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 KFP03329.1 - 0.0074 15.6 0.1 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) RUN PF02759.14 KFP03330.1 - 3.7e-13 49.3 0.4 4.1e-13 49.2 0.3 1.0 1 0 0 1 1 1 1 RUN domain PTB PF08416.8 KFP03331.1 - 1.1e-42 145.0 0.0 2.1e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PTEN_C2 PF10409.4 KFP03331.1 - 3.6e-31 107.6 0.0 5.9e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein SH2 PF00017.19 KFP03331.1 - 1.1e-08 34.7 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Thyroglobulin_1 PF00086.13 KFP03332.1 - 8.8e-22 76.2 3.6 8.8e-22 76.2 2.5 1.5 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat Thyroglobulin_1 PF00086.13 KFP03333.1 - 1.6e-18 65.7 0.9 3.1e-18 64.8 0.6 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Ribosomal_L37ae PF01780.14 KFP03334.1 - 1.6e-39 133.6 9.5 1.8e-39 133.5 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-C4_ClpX PF06689.8 KFP03334.1 - 0.018 14.5 0.3 0.018 14.5 0.2 1.6 2 0 0 2 2 2 0 ClpX C4-type zinc finger Rsm1 PF08600.5 KFP03334.1 - 0.019 14.7 0.6 0.027 14.3 0.4 1.2 1 0 0 1 1 1 0 Rsm1-like zf-DHHC PF01529.15 KFP03334.1 - 0.023 14.0 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Elf1 PF05129.8 KFP03334.1 - 0.026 14.1 0.3 0.035 13.7 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 KFP03334.1 - 0.032 13.9 0.8 0.044 13.4 0.6 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 KFP03334.1 - 0.053 12.9 2.7 0.087 12.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFP03334.1 - 0.06 13.1 1.6 0.089 12.6 1.1 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 KFP03334.1 - 0.16 12.3 0.7 0.74 10.2 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Rep_fac-A_C PF08646.5 KFP03334.1 - 0.2 11.3 2.3 0.3 10.7 1.6 1.4 1 1 0 1 1 1 0 Replication factor-A C terminal domain Zn-ribbon_8 PF09723.5 KFP03334.1 - 0.21 11.5 1.3 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 KFP03334.1 - 0.38 10.5 5.7 1.6 8.5 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger CarbpepA_inh PF02977.10 KFP03334.1 - 2.7 7.6 6.3 0.64 9.6 1.0 2.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor HARP PF07443.8 KFP03335.1 - 3.7e-51 170.3 0.5 1.7e-24 84.9 0.0 2.4 2 0 0 2 2 2 2 HepA-related protein (HARP) SNF2_N PF00176.18 KFP03335.1 - 1.8e-28 99.1 0.0 2.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFP03335.1 - 7e-12 45.0 0.0 1.8e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP03335.1 - 1.4e-05 24.9 0.0 0.022 14.6 0.0 3.2 2 2 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 KFP03335.1 - 0.00023 20.7 0.2 0.012 15.0 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFP03335.1 - 0.012 15.7 0.1 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RINGv PF12906.2 KFP03337.1 - 3.3e-07 30.2 10.5 6.7e-07 29.2 7.3 1.6 1 0 0 1 1 1 1 RING-variant domain Ku_N PF03731.10 KFP03339.1 - 1.3e-61 207.8 1.8 1.6e-61 207.6 0.3 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 KFP03339.1 - 2.8e-46 157.4 1.1 5e-46 156.6 0.7 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 KFP03339.1 - 7.5e-44 148.4 3.3 2.9e-42 143.3 0.9 2.8 2 0 0 2 2 2 1 Ku C terminal domain like Ku_C PF03730.9 KFP03339.1 - 5.3e-28 97.4 5.6 7.6e-28 96.8 2.6 2.4 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA PF00092.23 KFP03339.1 - 0.00078 19.2 0.1 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain AF1Q PF15017.1 KFP03339.1 - 0.28 11.1 2.7 0.37 10.7 0.6 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator TMEM169 PF15052.1 KFP03340.1 - 3.1e-70 234.2 9.0 4e-70 233.9 6.2 1.1 1 0 0 1 1 1 1 TMEM169 protein family TOBE_2 PF08402.5 KFP03340.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 TOBE domain THRAP3_BCLAF1 PF15440.1 KFP03340.1 - 0.29 9.7 6.9 0.35 9.4 4.8 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family adh_short_C2 PF13561.1 KFP03341.1 - 1.3e-27 97.0 0.1 1.6e-27 96.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFP03341.1 - 1.7e-22 80.1 0.1 2.1e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP03341.1 - 0.00019 21.1 0.0 0.00033 20.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KFP03341.1 - 0.0009 18.3 0.1 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase CABS1 PF15367.1 KFP03341.1 - 0.048 12.5 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 F420_oxidored PF03807.12 KFP03341.1 - 0.12 12.8 0.0 0.36 11.2 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 KFP03342.1 - 6.5e-65 218.8 0.0 8.1e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03342.1 - 6.2e-40 136.9 0.0 8.5e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 KFP03342.1 - 1.2e-12 47.3 0.2 2.5e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 KFP03342.1 - 4.6e-05 22.5 0.0 0.0014 17.6 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP03342.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Helicase_C_3 PF13625.1 KFP03343.1 - 7.4e-32 109.8 0.0 3.9e-31 107.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP03343.1 - 8.4e-15 55.0 0.0 2.8e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFP03343.1 - 4.1e-10 39.3 0.0 9.5e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFP03343.1 - 2.1e-06 27.3 0.0 4.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KFP03343.1 - 9.3e-06 24.6 0.2 1.6e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain TUSC2 PF15000.1 KFP03343.1 - 0.065 13.3 0.5 0.36 10.9 0.1 2.4 2 0 0 2 2 2 0 Tumour suppressor candidate 2 AAA_22 PF13401.1 KFP03343.1 - 0.1 12.7 0.0 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 KFP03344.1 - 1e-102 344.0 0.0 1.1e-102 343.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.13 KFP03345.1 - 1e-49 169.1 9.3 1.4e-49 168.6 6.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFP03345.1 - 1.5e-11 43.6 0.2 5.6e-11 41.8 0.1 1.9 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP03345.1 - 3.7e-07 29.4 0.2 8.9e-07 28.2 0.1 1.7 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP03345.1 - 2.5e-06 26.8 0.0 5.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IFT57 PF10498.4 KFP03345.1 - 0.019 13.7 4.1 0.41 9.3 0.3 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF241 PF03087.9 KFP03345.1 - 0.054 12.9 0.6 0.097 12.1 0.4 1.5 1 1 0 1 1 1 0 Arabidopsis protein of unknown function IR1-M PF12185.3 KFP03345.1 - 0.084 12.6 1.4 3.9 7.2 0.2 3.4 3 0 0 3 3 3 0 Nup358/RanBP2 E3 ligase domain FliS PF02561.9 KFP03345.1 - 0.13 12.0 1.9 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Flagellar protein FliS V-SNARE PF05008.10 KFP03345.1 - 0.24 11.6 3.1 1.4 9.1 0.0 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus ThylakoidFormat PF11264.3 KFP03345.1 - 0.53 9.8 4.6 0.32 10.5 0.8 2.0 2 0 0 2 2 2 0 Thylakoid formation protein Arfaptin PF06456.8 KFP03345.1 - 1.5 8.1 7.6 3.8 6.8 5.3 1.7 1 1 0 1 1 1 0 Arfaptin-like domain Spore_SspJ PF09575.5 KFP03347.1 - 0.0031 17.6 0.3 0.004 17.3 0.2 1.2 1 0 0 1 1 1 1 Small spore protein J (Spore_SspJ) Syndecan PF01034.15 KFP03347.1 - 0.0036 16.9 0.1 0.0047 16.5 0.1 1.2 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.6 KFP03347.1 - 0.0043 16.7 0.0 0.0047 16.5 0.0 1.1 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.1 KFP03347.1 - 0.0052 17.1 0.0 0.0061 16.9 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KFP03347.1 - 0.0062 16.7 0.0 0.0062 16.7 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator LRR19-TM PF15176.1 KFP03347.1 - 0.027 14.1 0.0 0.028 14.1 0.0 1.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Baculo_11_kDa PF06143.6 KFP03347.1 - 0.065 12.5 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Chordopox_A13L PF05961.6 KFP03347.1 - 0.091 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein OAD_gamma PF04277.8 KFP03347.1 - 0.095 13.0 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain OppC_N PF12911.2 KFP03347.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C ODV-E18 PF10717.4 KFP03347.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Adeno_E3_CR2 PF02439.10 KFP03347.1 - 0.42 10.1 6.4 0.67 9.5 4.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2970 PF11174.3 KFP03347.1 - 7.3 6.2 7.8 11 5.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Laminin_G_2 PF02210.19 KFP03348.1 - 1.7e-63 212.3 1.4 1.8e-22 79.7 0.0 3.2 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 KFP03348.1 - 2.6e-47 160.1 0.1 8e-19 67.9 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_3 PF13385.1 KFP03348.1 - 1.6e-10 41.4 0.1 0.0021 18.3 0.0 3.5 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 KFP03348.1 - 2.1e-05 24.3 35.5 4.1e-05 23.4 3.7 4.5 3 1 1 4 4 4 2 EGF-like domain COLFI PF01410.13 KFP03348.1 - 0.0017 17.8 0.1 0.049 13.0 0.1 2.4 2 0 0 2 2 2 1 Fibrillar collagen C-terminal domain EGF_2 PF07974.8 KFP03348.1 - 0.0032 17.5 12.6 0.0032 17.5 8.7 3.8 4 0 0 4 4 4 2 EGF-like domain PMP1_2 PF08114.6 KFP03348.1 - 0.023 14.1 0.6 0.045 13.2 0.4 1.4 1 0 0 1 1 1 0 ATPase proteolipid family OppC_N PF12911.2 KFP03348.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C RSN1_TM PF13967.1 KFP03348.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport IncA PF04156.9 KFP03348.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 IncA protein F5_F8_type_C PF00754.20 KFP03349.1 - 1.7e-15 57.0 1.6 1.9e-15 56.8 1.1 1.0 1 0 0 1 1 1 1 F5/8 type C domain CDC48_N PF02359.13 KFP03349.1 - 0.15 12.0 0.2 1.8 8.5 0.0 1.9 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Ras PF00071.17 KFP03350.1 - 3.6e-53 179.2 0.0 4.1e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP03350.1 - 9.1e-22 77.7 0.0 1.3e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFP03350.1 - 1e-07 31.6 0.1 3.2e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFP03350.1 - 1.2e-06 27.9 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP03350.1 - 1.3e-05 25.1 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KFP03350.1 - 0.015 14.8 0.6 0.073 12.6 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 KFP03350.1 - 0.038 13.1 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KFP03350.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 KFP03350.1 - 0.12 11.9 0.1 0.2 11.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain FERM_C PF09380.5 KFP03352.1 - 1e-20 73.6 0.0 1.9e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFP03352.1 - 6.4e-20 71.0 0.8 2.5e-19 69.0 0.0 2.4 3 0 0 3 3 3 1 FERM N-terminal domain FERM_M PF00373.13 KFP03352.1 - 2.4e-15 56.8 0.6 3.7e-13 49.7 0.4 2.5 1 1 0 1 1 1 1 FERM central domain FA PF08736.6 KFP03352.1 - 2e-14 53.0 11.3 4.7e-14 51.9 7.9 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) Ras PF00071.17 KFP03353.1 - 1.6e-54 183.6 0.1 1.9e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP03353.1 - 7.8e-18 65.1 0.1 1.4e-17 64.2 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFP03353.1 - 3.6e-10 39.3 0.0 4.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP03353.1 - 8.3e-06 25.3 0.0 3.4e-05 23.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP03353.1 - 1.7e-05 24.1 0.0 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFP03353.1 - 0.00064 19.6 0.0 0.0012 18.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP03353.1 - 0.0017 17.5 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KFP03353.1 - 0.0029 16.7 0.1 0.09 11.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 KFP03353.1 - 0.0083 15.1 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 2 Septin AAA_25 PF13481.1 KFP03353.1 - 0.0095 15.3 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFP03353.1 - 0.015 14.5 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B IMP_cyclohyd PF07826.6 KFP03353.1 - 0.084 12.2 0.1 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Ser_hydrolase PF06821.8 KFP03353.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase zf-C2H2 PF00096.21 KFP03354.1 - 1.4e-18 65.9 30.1 0.00063 19.9 0.3 6.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP03354.1 - 8e-16 57.4 30.2 3.2e-07 30.3 1.0 5.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP03354.1 - 2.9e-07 30.3 32.3 0.022 15.0 0.1 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger CP2 PF04516.10 KFP03355.1 - 6.6e-72 241.3 0.1 1e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor SAM_PNT PF02198.11 KFP03355.1 - 0.019 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain CLASP_N PF12348.3 KFP03356.1 - 2.2e-58 197.3 15.3 1e-38 132.9 0.4 4.7 4 1 1 5 5 5 3 CLASP N terminal HEAT PF02985.17 KFP03356.1 - 8e-20 69.1 9.5 9e-06 25.3 0.0 10.7 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.1 KFP03356.1 - 9.5e-14 51.4 6.8 0.0052 17.0 0.2 8.1 6 2 2 8 8 8 2 HEAT repeats HEAT_EZ PF13513.1 KFP03356.1 - 6.4e-11 42.4 4.5 0.058 13.9 0.0 6.7 6 0 0 6 6 5 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFP03356.1 - 1.8e-07 31.4 1.7 1.5 9.2 0.0 5.9 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Sec7_N PF12783.2 KFP03356.1 - 1.8e-07 30.7 5.0 0.003 17.0 0.0 4.9 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Adaptin_N PF01602.15 KFP03356.1 - 1.4e-06 26.9 7.2 1.1 7.5 0.0 6.1 5 2 0 7 7 7 3 Adaptin N terminal region DUF2435 PF10363.4 KFP03356.1 - 3.3e-05 23.7 2.1 0.43 10.5 0.0 4.2 3 1 0 3 3 3 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KFP03356.1 - 4.2e-05 23.4 6.1 0.0032 17.3 0.2 4.8 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 KFP03356.1 - 5.2e-05 23.1 2.9 0.49 10.3 0.0 5.5 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation ParcG PF10274.4 KFP03356.1 - 0.00019 21.4 0.5 0.0062 16.4 0.1 3.1 1 1 1 2 2 2 1 Parkin co-regulated protein TAN PF11640.3 KFP03356.1 - 0.00023 20.9 4.2 0.037 13.7 0.0 3.8 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair DUF2454 PF10521.4 KFP03356.1 - 0.0019 17.2 1.9 1.3 7.9 0.0 4.1 3 2 1 4 4 4 1 Protein of unknown function (DUF2454) TPR_20 PF14561.1 KFP03356.1 - 0.069 13.2 3.0 0.32 11.1 0.3 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat Nipped-B_C PF12830.2 KFP03356.1 - 0.13 11.8 2.5 9.9 5.7 0.0 3.8 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus hNIFK_binding PF12196.3 KFP03357.1 - 5.3e-15 54.5 3.8 9.1e-15 53.7 2.6 1.4 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK RRM_1 PF00076.17 KFP03357.1 - 8.2e-07 28.5 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03357.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03357.1 - 0.00026 20.9 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Translin PF01997.11 KFP03358.1 - 7.3e-45 153.0 0.2 8e-45 152.9 0.1 1.0 1 0 0 1 1 1 1 Translin family Glucos_trans_II PF14264.1 KFP03358.1 - 0.043 12.8 0.0 0.051 12.5 0.0 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII RhoGEF PF00621.15 KFP03359.1 - 1.6e-41 142.1 2.8 3.2e-41 141.1 1.9 1.5 1 0 0 1 1 1 1 RhoGEF domain Sda PF08970.5 KFP03359.1 - 0.021 14.3 0.7 0.043 13.2 0.5 1.5 1 0 0 1 1 1 0 Sporulation inhibitor A IQ PF00612.22 KFP03361.1 - 4.8e-10 38.1 26.7 2.9e-06 26.4 0.5 5.2 5 0 0 5 5 5 3 IQ calmodulin-binding motif Ndr PF03096.9 KFP03361.1 - 0.39 9.1 2.2 1.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Ndr family Caudo_TAP PF02413.12 KFP03361.1 - 4.3 7.5 12.4 0.15 12.2 2.2 2.7 2 1 0 2 2 2 0 Caudovirales tail fibre assembly protein EAF PF09816.4 KFP03362.1 - 1.4e-18 66.8 0.2 4.8e-18 65.1 0.0 2.0 2 1 0 2 2 2 1 RNA polymerase II transcription elongation factor Nha1_C PF08619.5 KFP03362.1 - 0.00048 19.5 9.4 0.00058 19.2 6.5 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DNA_pol_viral_N PF00242.12 KFP03362.1 - 0.08 11.9 6.3 0.095 11.7 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PAN_3 PF08277.7 KFP03362.1 - 0.15 11.7 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 PAN-like domain Cwf_Cwc_15 PF04889.7 KFP03362.1 - 0.23 11.1 12.2 0.36 10.5 8.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BBP1_C PF15272.1 KFP03362.1 - 0.34 10.4 5.8 0.53 9.8 4.1 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal PTR2 PF00854.16 KFP03363.1 - 2.8e-52 177.7 4.3 3.7e-52 177.3 3.0 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 KFP03363.1 - 4.2e-06 25.7 9.0 2.4e-05 23.2 6.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFP03363.1 - 0.0083 14.5 8.6 0.094 11.0 5.7 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein Cupin_8 PF13621.1 KFP03364.1 - 6.3e-38 130.7 0.0 8.5e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFP03364.1 - 2.3e-09 36.9 0.0 3.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KFP03364.1 - 0.00023 21.3 0.1 0.00047 20.3 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Pox_C7_F8A PF03287.9 KFP03364.1 - 0.058 13.1 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus C7/F8A protein MFS_1 PF07690.11 KFP03365.1 - 4.8e-06 25.5 27.3 4.8e-06 25.5 18.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sema PF01403.14 KFP03366.1 - 5.9e-137 456.7 0.3 1.8e-136 455.1 0.1 1.8 1 1 1 2 2 2 1 Sema domain TSP_1 PF00090.14 KFP03366.1 - 2.9e-39 132.9 94.1 1.8e-10 40.7 6.0 7.5 7 0 0 7 7 7 5 Thrombospondin type 1 domain 7TM_GPCR_Srz PF10325.4 KFP03366.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Thioredoxin PF00085.15 KFP03367.1 - 5.9e-75 247.6 1.5 7.4e-26 89.8 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_2 PF13098.1 KFP03367.1 - 4.7e-29 100.8 8.2 7.5e-09 35.7 0.1 5.0 4 2 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFP03367.1 - 4.2e-20 71.5 0.3 2e-05 24.5 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin-like Thioredoxin_8 PF13905.1 KFP03367.1 - 2.1e-18 66.2 1.6 9.1e-06 25.7 0.1 5.3 3 2 2 5 5 5 3 Thioredoxin-like AhpC-TSA PF00578.16 KFP03367.1 - 7.4e-17 61.1 1.1 1.7e-05 24.4 0.1 3.7 4 0 0 4 4 4 3 AhpC/TSA family Redoxin PF08534.5 KFP03367.1 - 2.3e-13 49.8 1.7 0.0026 17.3 0.0 3.4 2 1 1 3 3 3 3 Redoxin Thioredoxin_6 PF13848.1 KFP03367.1 - 9e-13 48.4 3.2 0.0026 17.5 0.0 4.8 5 0 0 5 5 5 3 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KFP03367.1 - 2.9e-09 36.5 0.1 0.03 13.8 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_3 PF13192.1 KFP03367.1 - 1e-06 28.4 0.2 0.014 15.1 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin domain HyaE PF07449.6 KFP03367.1 - 0.00056 19.7 0.0 4 7.3 0.0 3.7 4 1 0 4 4 4 2 Hydrogenase-1 expression protein HyaE TraF PF13728.1 KFP03367.1 - 0.00057 19.4 0.0 5.1 6.5 0.0 3.4 3 0 0 3 3 3 2 F plasmid transfer operon protein Glutaredoxin PF00462.19 KFP03367.1 - 0.0079 16.1 10.7 0.68 9.9 0.1 4.6 4 1 0 4 4 4 2 Glutaredoxin Thioredoxin_4 PF13462.1 KFP03367.1 - 0.043 13.8 6.4 2.8 7.9 0.3 3.7 2 1 0 2 2 2 0 Thioredoxin DSBA PF01323.15 KFP03367.1 - 0.35 10.4 5.2 16 4.9 0.1 4.6 3 3 3 6 6 6 0 DSBA-like thioredoxin domain Longin PF13774.1 KFP03368.1 - 4e-22 77.5 0.6 7.2e-22 76.7 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Guanylate_cyc PF00211.15 KFP03369.1 - 4e-121 401.1 2.8 6.7e-63 211.3 0.3 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1053 PF06327.9 KFP03369.1 - 7.7e-39 132.1 0.5 2.5e-38 130.4 0.3 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1053) HNOBA PF07701.9 KFP03369.1 - 0.0015 17.7 2.1 0.92 8.6 0.0 3.0 3 0 0 3 3 3 2 Heme NO binding associated PTPLA PF04387.9 KFP03370.1 - 7.1e-41 139.3 10.5 7.6e-41 139.2 7.3 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA I-set PF07679.11 KFP03371.1 - 1.1e-212 688.6 11.0 1.1e-28 98.8 0.0 10.1 10 0 0 10 10 10 9 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP03371.1 - 2.7e-91 299.7 13.5 3.7e-12 46.2 0.0 9.8 9 0 0 9 9 9 9 Immunoglobulin domain Pkinase PF00069.20 KFP03371.1 - 8.1e-71 238.2 0.0 1.5e-70 237.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain ig PF00047.20 KFP03371.1 - 4.6e-62 206.0 5.3 3e-08 33.6 0.0 9.9 9 0 0 9 9 9 9 Immunoglobulin domain V-set PF07686.12 KFP03371.1 - 1.6e-52 176.2 5.3 1.8e-06 27.8 0.0 12.0 9 3 0 9 9 9 9 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP03371.1 - 1.6e-49 166.1 2.5 1.9e-06 28.2 0.0 10.3 10 0 0 10 10 10 7 Immunoglobulin domain Pkinase_Tyr PF07714.12 KFP03371.1 - 4.6e-36 124.2 0.0 9.6e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.7 KFP03371.1 - 7.9e-23 80.1 5.5 0.027 14.3 0.0 9.5 9 0 0 9 9 8 6 CD80-like C2-set immunoglobulin domain fn3 PF00041.16 KFP03371.1 - 2.6e-17 62.7 2.5 5.3e-17 61.7 0.2 2.7 2 0 0 2 2 2 1 Fibronectin type III domain BiPBP_C PF06832.7 KFP03371.1 - 2.1e-13 49.9 0.1 0.68 9.8 0.0 8.8 9 1 0 9 9 9 3 Penicillin-Binding Protein C-terminus Family Receptor_2B4 PF11465.3 KFP03371.1 - 7.3e-10 38.7 0.1 0.21 11.5 0.0 7.5 7 0 0 7 7 7 2 Natural killer cell receptor 2B4 Herpes_gI PF01688.12 KFP03371.1 - 0.015 14.4 0.0 14 4.8 0.0 3.7 4 0 0 4 4 4 0 Alphaherpesvirus glycoprotein I Kdo PF06293.9 KFP03371.1 - 0.018 14.0 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family V-set_CD47 PF08204.6 KFP03371.1 - 0.029 14.1 7.2 14 5.4 0.0 5.9 7 0 0 7 7 7 0 CD47 immunoglobulin-like domain Kelch_1 PF01344.20 KFP03371.1 - 0.85 9.2 3.5 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 Kelch motif CCDC14 PF15254.1 KFP03373.1 - 0 1052.5 33.2 0 1052.3 23.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 Spectrin PF00435.16 KFP03374.1 - 2.3e-44 149.9 82.5 1.5e-10 41.3 1.5 9.6 7 2 1 8 8 8 6 Spectrin repeat RhoGEF PF00621.15 KFP03374.1 - 1e-35 123.2 0.4 1e-35 123.2 0.3 5.0 4 1 0 5 5 5 1 RhoGEF domain CRAL_TRIO_2 PF13716.1 KFP03374.1 - 5.2e-17 62.1 0.0 4.6e-15 55.8 0.0 3.4 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain SH3_9 PF14604.1 KFP03374.1 - 3.6e-08 32.8 0.1 1.6e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFP03374.1 - 2.5e-07 29.9 0.0 8.3e-07 28.3 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFP03374.1 - 5.3e-05 22.6 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFP03374.1 - 0.0018 18.4 7.1 0.0023 18.1 0.2 3.8 4 0 0 4 4 4 1 PH domain KIP1 PF07765.7 KFP03374.1 - 0.03 14.1 2.3 1.9 8.4 0.1 4.9 4 0 0 4 4 4 0 KIP1-like protein Pkinase PF00069.20 KFP03375.1 - 2.3e-17 63.0 0.0 2.6e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03375.1 - 4.6e-06 25.8 0.0 6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase T2SK PF03934.8 KFP03375.1 - 0.072 12.2 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K OMPdecase PF00215.19 KFP03376.1 - 5.1e-76 255.0 0.0 8.3e-76 254.3 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 KFP03376.1 - 2e-12 46.9 0.2 1.1e-11 44.5 0.1 2.3 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Integrin_beta PF00362.13 KFP03377.1 - 4.1e-180 599.2 0.0 6.7e-180 598.5 0.0 1.3 1 0 0 1 1 1 1 Integrin, beta chain Integrin_b_cyt PF08725.6 KFP03377.1 - 1.1e-18 66.3 0.2 1.1e-18 66.3 0.1 1.7 2 0 0 2 2 2 1 Integrin beta cytoplasmic domain Integrin_B_tail PF07965.7 KFP03377.1 - 2.9e-17 62.8 4.8 2.9e-17 62.8 3.3 4.5 4 2 1 5 5 5 1 Integrin beta tail domain EGF_2 PF07974.8 KFP03377.1 - 2.3e-06 27.6 74.5 0.00077 19.5 10.8 4.7 4 0 0 4 4 4 3 EGF-like domain DUF2975 PF11188.3 KFP03377.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) EGF_CA PF07645.10 KFP03379.1 - 7.8e-07 28.9 5.7 7.8e-07 28.9 4.0 4.7 2 2 3 5 5 5 2 Calcium-binding EGF domain EGF PF00008.22 KFP03379.1 - 1.6e-06 27.9 3.5 1.6e-06 27.9 2.4 3.8 3 1 1 4 4 4 2 EGF-like domain EGF_MSP1_1 PF12946.2 KFP03379.1 - 0.00015 21.4 6.5 0.00015 21.4 4.5 3.7 2 1 1 3 3 3 1 MSP1 EGF domain 1 EGF_3 PF12947.2 KFP03379.1 - 0.0007 19.5 23.3 0.0075 16.2 4.7 3.5 2 1 1 3 3 3 2 EGF domain Orthoreo_P10 PF07204.6 KFP03379.1 - 0.011 15.4 0.2 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 hEGF PF12661.2 KFP03379.1 - 0.034 14.2 7.7 1.9 8.7 0.4 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF FXa_inhibition PF14670.1 KFP03379.1 - 0.27 11.3 31.9 0.09 12.9 7.5 4.2 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP03379.1 - 1 9.0 23.8 0.57 9.8 1.4 4.9 5 0 0 5 5 5 0 Complement Clr-like EGF-like AA_permease PF00324.16 KFP03380.1 - 2.8e-44 151.2 38.9 2.8e-44 151.2 26.9 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KFP03380.1 - 1.9e-18 66.2 44.4 1.9e-18 66.2 30.8 2.1 2 0 0 2 2 2 1 Amino acid permease zf-H2C2_2 PF13465.1 KFP03381.1 - 2.7e-24 84.1 22.8 1.2e-07 31.6 0.2 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03381.1 - 2.2e-13 49.6 37.8 0.00062 19.9 2.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03381.1 - 4e-08 33.0 34.2 0.031 14.6 3.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 KFP03381.1 - 0.17 11.7 13.7 0.25 11.1 1.9 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 KFP03381.1 - 0.35 10.7 8.0 1.4 8.8 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.3 KFP03381.1 - 0.42 10.8 16.8 3.8 7.7 0.5 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PX PF00787.19 KFP03382.1 - 1.5e-22 79.5 0.0 3.5e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KFP03382.1 - 2.7e-07 30.1 11.2 0.0005 19.4 2.8 2.2 1 1 1 2 2 2 2 Vps5 C terminal like V-SNARE PF05008.10 KFP03382.1 - 2.6 8.2 7.6 0.82 9.8 0.5 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Pkinase PF00069.20 KFP03383.1 - 3e-46 157.6 0.0 5e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ecTbetaR2 PF08917.5 KFP03383.1 - 9.9e-40 134.9 14.2 9.9e-40 134.9 9.9 2.0 2 0 0 2 2 2 1 Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr PF07714.12 KFP03383.1 - 1.3e-28 99.7 0.0 3.3e-28 98.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase BLVR PF06375.6 KFP03383.1 - 0.029 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SIT PF15330.1 KFP03383.1 - 0.071 13.2 0.1 0.84 9.8 0.0 2.5 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Oxysterol_BP PF01237.13 KFP03384.1 - 7.1e-71 238.5 0.1 5.9e-70 235.5 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 KFP03384.1 - 1e-11 44.9 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFP03384.1 - 1.4e-08 34.6 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 KFP03384.1 - 2.6e-05 24.2 0.0 6.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 KFP03384.1 - 0.0026 17.8 0.1 0.0073 16.4 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KFP03384.1 - 0.0042 17.3 0.3 0.11 12.7 0.2 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain NAD_Gly3P_dh_C PF07479.9 KFP03385.1 - 1.9e-57 193.1 0.3 3.6e-57 192.2 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KFP03385.1 - 1.1e-46 158.4 0.0 2.4e-46 157.3 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pox_VLTF3 PF04947.9 KFP03385.1 - 0.1 12.1 0.6 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like Peptidase_M8 PF01457.11 KFP03386.1 - 5.5e-79 265.8 1.0 3.9e-53 180.5 0.0 2.0 1 1 1 2 2 2 2 Leishmanolysin WWE PF02825.15 KFP03387.1 - 4.1e-07 29.3 0.1 1.6e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 WWE domain SLS PF14611.1 KFP03387.1 - 0.023 14.1 1.7 0.036 13.5 1.0 1.4 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator LSM PF01423.17 KFP03387.1 - 0.071 12.6 0.5 0.33 10.5 0.0 2.2 2 1 0 2 2 2 0 LSM domain DUF4019 PF13211.1 KFP03388.1 - 0.0039 17.4 0.0 0.0051 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4019) RRM_6 PF14259.1 KFP03388.1 - 0.0043 17.0 0.1 0.021 14.7 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ING PF12998.2 KFP03388.1 - 0.0057 16.9 0.9 0.024 14.9 0.8 1.7 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Spindle_Spc25 PF08234.7 KFP03388.1 - 0.0095 15.9 0.2 0.021 14.8 0.1 1.5 1 1 0 1 1 1 1 Chromosome segregation protein Spc25 P53 PF00870.13 KFP03388.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 P53 DNA-binding domain PA-IL PF07828.7 KFP03389.1 - 0.084 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 PA-IL-like protein zf-C3HC4 PF00097.20 KFP03390.1 - 2e-07 30.5 14.4 4.3e-07 29.4 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP03390.1 - 2.6e-07 30.3 9.7 5.2e-07 29.3 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP03390.1 - 1.4e-06 28.1 13.0 3.2e-06 27.0 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP03390.1 - 8.5e-06 25.3 9.6 1.8e-05 24.3 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP03390.1 - 0.0021 17.7 12.9 0.0042 16.7 8.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Endonuclease_7 PF02945.10 KFP03390.1 - 0.0024 17.5 3.3 0.006 16.2 2.3 1.6 1 0 0 1 1 1 1 Recombination endonuclease VII zf-Nse PF11789.3 KFP03390.1 - 0.017 14.6 9.6 0.045 13.2 6.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit KH_1 PF00013.24 KFP03390.1 - 0.02 14.5 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 KH domain zf-rbx1 PF12678.2 KFP03390.1 - 0.02 15.0 9.5 0.057 13.5 6.6 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 KFP03390.1 - 0.028 14.1 2.7 0.057 13.2 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Siva PF05458.7 KFP03390.1 - 0.03 13.8 1.8 0.065 12.8 1.2 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-C3HC4_4 PF15227.1 KFP03390.1 - 0.041 13.7 9.9 0.1 12.4 6.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2877 PF11392.3 KFP03390.1 - 0.059 13.5 0.1 1.5 9.0 0.0 3.1 4 0 0 4 4 3 0 Protein of unknown function (DUF2877) DZR PF12773.2 KFP03390.1 - 0.69 9.7 10.4 1.2 9.0 6.6 1.9 2 0 0 2 2 1 0 Double zinc ribbon zf-MIZ PF02891.15 KFP03390.1 - 1.3 8.5 10.2 3.1 7.3 7.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Maf1 PF09174.5 KFP03390.1 - 2.7 7.7 7.6 0.3 10.9 0.3 2.5 2 0 0 2 2 2 0 Maf1 regulator Macro PF01661.16 KFP03391.1 - 3.3e-44 149.5 0.5 9.9e-34 115.7 0.5 2.5 2 0 0 2 2 2 2 Macro domain PARP PF00644.15 KFP03391.1 - 7.1e-05 22.3 0.6 7.1e-05 22.3 0.4 2.5 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain FAIM1 PF06905.8 KFP03392.1 - 7.2e-90 298.9 3.7 8.5e-90 298.6 2.6 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) 5_nucleotid_C PF02872.13 KFP03392.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.6 1 1 0 2 2 2 0 5'-nucleotidase, C-terminal domain C2 PF00168.25 KFP03393.1 - 3.5e-31 106.8 0.3 2.7e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 KFP03393.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) PapD-like PF14874.1 KFP03395.1 - 0.0001 22.2 0.1 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Flagellar-associated PapD-like 7tm_2 PF00002.19 KFP03396.1 - 2.1e-86 288.9 17.3 2.7e-86 288.6 12.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP03396.1 - 2.9e-18 65.6 3.2 2.9e-18 65.6 2.2 1.8 2 0 0 2 2 2 1 Hormone receptor domain DUF4233 PF14017.1 KFP03396.1 - 7 6.6 11.9 1.1 9.1 2.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) TMEM37 PF15108.1 KFP03397.1 - 1.6e-87 291.9 14.0 1.8e-87 291.8 9.7 1.0 1 0 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family SK_channel PF03530.9 KFP03397.1 - 9 6.1 9.4 1.1 9.0 1.3 2.3 1 1 0 2 2 2 0 Calcium-activated SK potassium channel DUF2340 PF10209.4 KFP03398.1 - 1.1e-45 154.6 0.0 1.3e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Ferric_reduct PF01794.14 KFP03399.1 - 5.8e-19 68.4 5.4 1.8e-16 60.3 2.4 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component F420_oxidored PF03807.12 KFP03399.1 - 4.1e-16 59.1 0.1 3e-15 56.4 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFP03399.1 - 8.2e-05 22.5 0.0 0.00025 20.9 0.0 1.8 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KFP03399.1 - 0.00053 19.3 0.0 0.00093 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 KFP03399.1 - 0.0018 18.3 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KFP03399.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF781 PF05612.7 KFP03399.1 - 0.022 13.4 0.2 0.085 11.5 0.0 2.0 2 0 0 2 2 2 0 Mouse protein of unknown function (DUF781) NAD_Gly3P_dh_N PF01210.18 KFP03399.1 - 0.058 13.1 0.2 2.2 8.0 0.1 2.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KFP03399.1 - 0.067 12.1 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase C1q PF00386.16 KFP03400.1 - 1.3e-18 67.2 0.0 1.4e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 C1q domain TNF PF00229.13 KFP03400.1 - 0.0082 15.7 0.0 0.0091 15.5 0.0 1.1 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.13 KFP03401.1 - 9.5e-37 124.3 123.2 9.9e-10 37.8 17.9 4.8 2 2 2 4 4 4 4 Collagen triple helix repeat (20 copies) SRCR PF00530.13 KFP03401.1 - 3.5e-28 97.8 1.6 6e-28 97.0 1.1 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFP03401.1 - 9e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain MHC2-interact PF09307.5 KFP03401.1 - 0.00058 19.6 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 CLIP, MHC2 interacting INSIG PF07281.7 KFP03402.1 - 9e-57 191.5 0.7 1e-56 191.4 0.5 1.0 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) OMP_b-brl PF13505.1 KFP03402.1 - 0.025 14.5 0.1 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain KOG2701 PF09762.4 KFP03403.1 - 1.4e-80 269.6 0.1 1.4e-80 269.6 0.0 3.7 2 1 1 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) Baculo_PEP_C PF04513.7 KFP03403.1 - 0.056 13.2 6.7 0.079 12.7 1.3 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PMC2NT PF08066.7 KFP03403.1 - 0.32 11.3 16.3 1 9.7 1.3 4.0 3 1 0 4 4 4 0 PMC2NT (NUC016) domain NPV_P10 PF05531.7 KFP03403.1 - 0.64 10.3 9.0 2.7 8.2 2.5 3.7 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 KFP03403.1 - 2.7 7.3 51.8 2.8 7.3 7.4 3.4 1 1 2 3 3 3 0 Intermediate filament protein DUF1664 PF07889.7 KFP03403.1 - 8.9 6.1 21.5 0.27 11.0 2.1 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) 7tm_1 PF00001.16 KFP03404.1 - 1.3e-74 250.6 9.3 1.7e-74 250.1 6.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP03404.1 - 1.2e-05 24.5 5.7 3.5e-05 23.0 3.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP03404.1 - 0.0047 16.0 2.4 0.0047 16.0 1.7 2.4 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF3278 PF11683.3 KFP03404.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3278) IclR PF01614.13 KFP03405.1 - 0.052 13.2 0.2 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial transcriptional regulator MBOAT_2 PF13813.1 KFP03405.1 - 0.16 12.0 3.2 0.13 12.3 0.8 1.8 1 1 1 2 2 2 0 Membrane bound O-acyl transferase family DEAD PF00270.24 KFP03406.1 - 4.2e-46 156.5 0.0 9.5e-46 155.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP03406.1 - 1.5e-21 76.0 0.0 4.5e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KFP03406.1 - 2.6e-19 68.4 0.4 4.8e-19 67.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFP03406.1 - 1.1e-05 25.3 0.7 1.7e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DPPIV_N PF00930.16 KFP03407.1 - 1.5e-109 365.8 0.2 2e-109 365.4 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFP03407.1 - 3.5e-49 166.8 0.0 5.4e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFP03407.1 - 4.7e-07 29.6 0.0 8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFP03407.1 - 3.8e-06 26.3 0.2 3e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KFP03407.1 - 2.3e-05 24.4 0.0 0.00032 20.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 KFP03407.1 - 0.00013 21.5 0.0 1.2 8.9 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.11 KFP03407.1 - 0.0006 19.3 2.3 0.0012 18.3 0.1 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KFP03407.1 - 0.0012 18.4 0.0 0.013 15.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KFP03407.1 - 0.018 14.4 0.0 2.4 7.5 0.0 2.7 2 1 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KFP03407.1 - 0.022 14.4 0.6 0.14 11.8 0.2 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Amdo_NSP PF12475.3 KFP03408.1 - 0.023 14.5 0.1 0.17 11.8 0.1 2.6 1 0 0 1 1 1 0 Amdovirus non-structural protein LRR_4 PF12799.2 KFP03409.1 - 6.8e-10 38.3 9.0 0.00067 19.2 0.1 4.5 2 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP03409.1 - 4.1e-05 23.2 5.4 0.0019 17.9 0.3 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 KFP03409.1 - 0.025 14.1 0.1 0.056 12.9 0.1 1.6 1 1 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.28 KFP03409.1 - 0.027 14.4 9.6 28 5.2 0.0 5.7 5 2 1 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 KFP03409.1 - 0.21 11.8 8.6 28 5.5 0.0 5.5 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 KFP03409.1 - 0.26 11.4 6.2 14 6.1 0.0 4.8 5 1 0 5 5 5 0 Leucine Rich repeat Serpin PF00079.15 KFP03410.1 - 2.3e-120 402.1 1.7 2.6e-120 401.9 1.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF1280 PF06918.9 KFP03410.1 - 0.02 14.1 0.2 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) DUF1241 PF06840.6 KFP03411.1 - 4.3e-66 220.9 4.4 6.1e-66 220.4 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Med11 PF10280.4 KFP03411.1 - 0.0012 18.9 1.8 0.004 17.1 0.4 2.2 1 1 1 2 2 2 1 Mediator complex protein FH2 PF02181.18 KFP03411.1 - 0.0037 16.2 2.5 0.0037 16.2 1.7 1.6 1 1 0 1 1 1 1 Formin Homology 2 Domain BLOC1_2 PF10046.4 KFP03411.1 - 0.0064 16.6 1.4 0.016 15.3 0.3 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.6 KFP03411.1 - 0.02 12.4 1.6 0.023 12.2 1.1 1.2 1 0 0 1 1 1 0 Prominin Decorin_bind PF02352.10 KFP03411.1 - 0.047 13.6 2.4 0.5 10.3 0.3 2.4 2 0 0 2 2 2 0 Decorin binding protein Hormone_1 PF00103.15 KFP03411.1 - 0.051 12.9 0.5 0.095 12.0 0.3 1.5 1 0 0 1 1 1 0 Somatotropin hormone family Sec23_trunk PF04811.10 KFP03411.1 - 0.085 12.1 1.5 1.1 8.6 0.2 2.6 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain DUF2852 PF11014.3 KFP03411.1 - 0.21 11.5 1.9 0.31 11.0 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) DUF4358 PF14270.1 KFP03411.1 - 0.28 11.0 3.2 11 5.9 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4358) Syntaxin_2 PF14523.1 KFP03411.1 - 1.1 9.3 5.5 0.44 10.5 1.9 1.9 2 0 0 2 2 2 0 Syntaxin-like protein CENP-Q PF13094.1 KFP03412.1 - 0.00026 21.0 7.7 0.00028 20.9 5.3 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit KLRAQ PF10205.4 KFP03412.1 - 0.0066 16.4 5.8 0.008 16.2 4.0 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein TMCO5 PF14992.1 KFP03412.1 - 0.018 14.1 3.9 0.018 14.2 2.7 1.1 1 0 0 1 1 1 0 TMCO5 family DUF972 PF06156.8 KFP03412.1 - 0.039 14.2 3.7 0.047 14.0 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) OprD PF03573.8 KFP03412.1 - 0.046 12.4 0.2 0.05 12.3 0.1 1.1 1 0 0 1 1 1 0 outer membrane porin, OprD family DUF2968 PF11180.3 KFP03412.1 - 0.05 12.9 5.8 0.054 12.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF342 PF03961.8 KFP03412.1 - 0.088 11.2 2.6 0.087 11.2 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 KFP03412.1 - 0.09 13.2 0.9 0.14 12.5 0.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.6 KFP03412.1 - 0.11 12.1 3.0 0.14 11.8 2.1 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Herpes_UL6 PF01763.11 KFP03412.1 - 0.2 9.7 4.4 0.22 9.6 3.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like C2-set PF05790.10 KFP03412.1 - 0.21 11.5 3.4 0.26 11.3 2.4 1.2 1 0 0 1 1 1 0 Immunoglobulin C2-set domain YlqD PF11068.3 KFP03412.1 - 0.29 11.1 7.5 0.38 10.8 5.2 1.2 1 0 0 1 1 1 0 YlqD protein Mnd1 PF03962.10 KFP03412.1 - 0.43 10.2 7.6 0.45 10.1 5.3 1.0 1 0 0 1 1 1 0 Mnd1 family AChE_tetra PF08674.5 KFP03415.1 - 9.4e-20 69.8 7.1 1.4e-19 69.2 5.0 1.3 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain Pkinase_Tyr PF07714.12 KFP03416.1 - 9e-103 342.8 0.0 1.2e-102 342.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP03416.1 - 1.3e-46 158.8 0.0 2.4e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Cadherin PF00028.12 KFP03416.1 - 1.1e-18 67.2 0.1 2.1e-09 37.5 0.0 4.8 4 1 0 4 4 4 2 Cadherin domain Cadherin_2 PF08266.7 KFP03416.1 - 0.01 15.4 0.2 2.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Cadherin-like RIO1 PF01163.17 KFP03416.1 - 0.026 13.8 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family CHGN PF05679.11 KFP03417.1 - 8.6e-60 202.8 0.0 1.2e-59 202.4 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 KFP03417.1 - 3.3e-09 36.0 0.2 7.2e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP03417.1 - 8.1e-07 28.4 0.0 1.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 KfrA_N PF11740.3 KFP03417.1 - 0.0046 17.3 0.2 0.0087 16.5 0.2 1.4 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term DUF4525 PF15027.1 KFP03417.1 - 0.0065 15.9 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4525) IncA PF04156.9 KFP03417.1 - 0.0071 15.9 2.3 0.014 15.0 1.6 1.4 1 0 0 1 1 1 1 IncA protein Dsl1_N PF11988.3 KFP03417.1 - 0.01 14.7 0.1 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal FadA PF09403.5 KFP03417.1 - 0.016 15.2 0.6 0.036 14.0 0.4 1.6 1 0 0 1 1 1 0 Adhesion protein FadA Prefoldin PF02996.12 KFP03417.1 - 0.054 13.1 2.2 0.16 11.5 1.5 1.8 1 0 0 1 1 1 0 Prefoldin subunit Striatin PF08232.7 KFP03417.1 - 0.21 11.9 4.9 0.39 11.0 3.4 1.3 1 0 0 1 1 1 0 Striatin family Fib_alpha PF08702.5 KFP03417.1 - 0.29 11.2 5.2 0.29 11.2 2.6 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PPV_E1_N PF00524.13 KFP03417.1 - 1.1 9.4 5.9 4 7.6 1.3 2.3 2 0 0 2 2 2 0 E1 Protein, N terminal domain RasGEF PF00617.14 KFP03418.1 - 1.1e-46 158.8 2.1 1.1e-46 158.8 1.4 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KFP03418.1 - 1.5e-13 50.7 0.2 7.8e-13 48.4 0.1 2.2 3 0 0 3 3 3 1 RasGEF N-terminal motif DUF2605 PF10792.4 KFP03418.1 - 0.065 12.9 0.9 0.81 9.3 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2605) Taeniidae_ag PF05596.6 KFP03418.1 - 0.068 12.9 1.9 5.6 6.8 0.1 3.5 3 1 0 3 3 3 0 Taeniidae antigen VHS PF00790.14 KFP03418.1 - 0.07 12.7 1.6 0.78 9.3 0.1 2.3 1 1 1 2 2 2 0 VHS domain Lectin_C PF00059.16 KFP03420.1 - 2.7e-17 63.3 0.0 3e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Lectin C-type domain Lectin_C PF00059.16 KFP03421.1 - 9.9e-18 64.7 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Lectin C-type domain S-AdoMet_synt_C PF02773.11 KFP03422.1 - 7.4e-78 258.9 0.3 1.2e-77 258.3 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KFP03422.1 - 4.5e-48 162.1 0.0 7.8e-48 161.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KFP03422.1 - 2.7e-42 143.0 0.1 5.6e-42 142.0 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Dpy-30 PF05186.8 KFP03423.1 - 2.4e-14 52.5 0.1 4e-14 51.7 0.0 1.4 2 0 0 2 2 2 1 Dpy-30 motif RIIa PF02197.12 KFP03423.1 - 0.07 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit UPF0444 PF15475.1 KFP03425.1 - 0.032 14.2 0.1 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Tetraspannin PF00335.15 KFP03426.1 - 1e-43 149.1 13.1 1.2e-43 148.9 9.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Sensor PF13796.1 KFP03426.1 - 4.9 6.7 12.6 0.65 9.5 4.2 2.3 3 0 0 3 3 3 0 Putative sensor Arm PF00514.18 KFP03427.1 - 3.8e-21 74.0 23.2 5.2e-08 32.4 0.2 8.0 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP03427.1 - 1.5e-11 44.4 15.3 0.0017 18.6 0.0 5.6 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 KFP03427.1 - 1.2e-06 28.1 4.7 0.094 12.8 0.1 5.6 5 0 0 5 5 5 1 HEAT repeat V-ATPase_H_C PF11698.3 KFP03427.1 - 4.9e-05 23.2 10.8 6.7e-05 22.7 0.1 4.1 4 0 0 4 4 4 1 V-ATPase subunit H HEAT_EZ PF13513.1 KFP03427.1 - 0.00012 22.4 8.7 0.23 12.0 0.0 5.4 5 1 0 5 5 5 2 HEAT-like repeat Vps39_1 PF10366.4 KFP03427.1 - 0.029 14.3 1.4 0.029 14.3 0.9 4.1 2 2 1 4 4 4 0 Vacuolar sorting protein 39 domain 1 PUL PF08324.6 KFP03427.1 - 0.032 13.0 5.0 0.057 12.2 0.1 2.9 3 1 0 3 3 3 0 PUL domain IBN_N PF03810.14 KFP03427.1 - 0.075 12.9 1.6 4.9 7.1 0.1 3.2 2 0 0 2 2 2 0 Importin-beta N-terminal domain dsDNA_bind PF01984.15 KFP03427.1 - 0.32 11.0 0.0 0.32 11.0 0.0 3.7 3 1 0 3 3 3 0 Double-stranded DNA-binding domain SH2 PF00017.19 KFP03428.1 - 2.1e-11 43.4 0.3 6.1e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 SH2 domain RVT_1 PF00078.22 KFP03429.1 - 0.028 13.7 0.0 0.056 12.7 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Muted PF14942.1 KFP03431.1 - 9.3e-58 194.2 15.9 1e-57 194.0 11.0 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Tox-REase-2 PF15646.1 KFP03431.1 - 0.055 13.3 6.7 0.88 9.4 2.3 2.2 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 DUF445 PF04286.7 KFP03431.1 - 0.17 11.3 8.1 0.2 11.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Spc7 PF08317.6 KFP03431.1 - 0.34 9.5 13.7 0.4 9.2 9.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.9 KFP03431.1 - 0.36 10.7 11.6 0.48 10.3 8.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FliD_C PF07195.7 KFP03431.1 - 0.42 9.8 8.7 1.2 8.4 6.0 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF148 PF02520.12 KFP03431.1 - 0.59 9.9 9.9 0.4 10.4 3.5 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF148 AAA_11 PF13086.1 KFP03431.1 - 0.7 9.4 5.1 0.83 9.1 3.5 1.1 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 KFP03431.1 - 1 9.2 16.9 0.11 12.4 4.3 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding UMPH-1 PF05822.7 KFP03431.1 - 1.9 7.7 8.5 3.2 6.9 5.8 1.4 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) AAA_23 PF13476.1 KFP03431.1 - 2.1 8.6 10.2 3.3 8.0 7.1 1.3 1 0 0 1 1 1 0 AAA domain DUF3966 PF13110.1 KFP03431.1 - 2.5 7.9 10.8 18 5.1 7.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3966) Exonuc_VII_L PF02601.10 KFP03431.1 - 3.2 6.8 9.5 4.3 6.4 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRP1_N PF06424.7 KFP03431.1 - 7.9 6.8 9.1 10 6.4 6.3 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal GST_C PF00043.20 KFP03432.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFP03432.1 - 2.3e-06 28.0 0.1 3.8e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFP03432.1 - 4.5e-06 26.4 0.0 7.6e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UAA PF08449.6 KFP03433.1 - 1.1e-96 323.3 24.6 1.4e-96 323.0 17.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFP03433.1 - 0.0017 18.4 12.3 0.0017 18.4 8.5 3.1 2 1 0 3 3 3 2 EamA-like transporter family DUF4193 PF13834.1 KFP03436.1 - 0.87 9.7 4.3 1.4 9.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) TF_AP-2 PF03299.9 KFP03437.1 - 2.2e-95 318.1 0.0 2.5e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor AP-2 FlhD PF05247.8 KFP03437.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) Branch PF02485.16 KFP03438.1 - 1.1e-54 185.1 0.0 1.4e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Tmemb_14 PF03647.8 KFP03439.1 - 2.1e-18 66.4 6.7 2.9e-18 66.0 4.7 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C Myco_arth_vir_N PF09610.5 KFP03439.1 - 0.32 10.9 2.7 7.6 6.5 0.2 2.5 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF1212 PF06738.7 KFP03439.1 - 0.6 9.5 3.1 0.31 10.4 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) DUF308 PF03729.8 KFP03439.1 - 0.88 9.6 5.9 0.097 12.6 0.7 1.9 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) Pkinase PF00069.20 KFP03440.1 - 7.2e-75 251.4 0.0 9.3e-75 251.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03440.1 - 4.6e-36 124.2 0.2 1.8e-35 122.3 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase GCM PF03615.10 KFP03441.1 - 5.4e-78 259.4 1.8 1.1e-77 258.4 1.2 1.5 1 0 0 1 1 1 1 GCM motif protein ELO PF01151.13 KFP03442.1 - 1.6e-61 207.7 23.8 1.8e-61 207.6 16.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3513 PF12026.3 KFP03443.1 - 5.4e-87 290.7 6.5 5.4e-87 290.7 4.5 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3513) Serine_rich PF08824.5 KFP03443.1 - 6.3e-60 201.4 3.0 6.3e-60 201.4 2.0 1.8 2 0 0 2 2 2 1 Serine rich protein interaction domain SH3_9 PF14604.1 KFP03443.1 - 5.7e-14 51.4 0.0 1.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP03443.1 - 3.5e-11 42.3 0.0 6.6e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP03443.1 - 4.4e-11 42.1 0.0 7.6e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Tmemb_170 PF10190.4 KFP03444.1 - 5e-47 158.2 11.0 5.5e-47 158.1 7.6 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1691 PF07950.6 KFP03444.1 - 0.036 13.9 1.8 0.041 13.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 KFP03444.1 - 3.2 7.6 10.0 0.86 9.4 4.6 1.7 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF3353 PF11833.3 KFP03444.1 - 3.4 7.0 5.1 7.4 5.9 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Far-17a_AIG1 PF04750.9 KFP03445.1 - 1.9e-59 200.2 14.8 2.2e-59 200.0 10.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein zf-C2H2 PF00096.21 KFP03446.1 - 5.1e-18 64.2 45.3 0.00017 21.6 1.1 6.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP03446.1 - 1.6e-10 40.7 11.3 1.4e-07 31.4 0.4 6.1 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP03446.1 - 2.7e-09 36.8 40.0 0.0065 16.5 1.0 6.1 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFP03446.1 - 2.5e-05 24.2 35.8 0.0031 17.7 1.4 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP03446.1 - 5.6e-05 22.8 2.3 5.6e-05 22.8 1.6 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KFP03446.1 - 0.2 11.8 38.1 1.2 9.4 0.8 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type DUF3573 PF12097.3 KFP03446.1 - 1.8 7.1 13.3 0.84 8.1 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3573) zf-H2C2_5 PF13909.1 KFP03446.1 - 2.3 8.6 31.0 0.045 13.9 3.0 5.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Endothelin PF00322.12 KFP03447.1 - 8.4e-23 79.2 11.6 2.4e-17 61.8 1.7 2.4 2 0 0 2 2 2 2 Endothelin family DB PF01682.14 KFP03447.1 - 0.026 14.5 4.7 0.033 14.2 2.6 1.7 1 1 0 1 1 1 0 DB module Glyco_hydro_38 PF01074.17 KFP03447.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain RPEL PF02755.10 KFP03448.1 - 3.4e-37 124.7 26.5 4.9e-10 38.4 1.6 4.8 4 0 0 4 4 4 4 RPEL repeat RabGAP-TBC PF00566.13 KFP03449.1 - 6e-05 22.6 5.2 0.0012 18.3 2.9 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GFO_IDH_MocA PF01408.17 KFP03450.1 - 7.1e-08 33.0 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFP03450.1 - 0.0019 18.0 0.1 0.0054 16.5 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Tmemb_14 PF03647.8 KFP03451.1 - 5e-21 74.9 4.1 5.4e-21 74.7 2.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C WD40 PF00400.27 KFP03452.1 - 8.6e-31 104.7 7.9 2.5e-08 33.4 0.3 6.1 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KFP03452.1 - 9.5e-05 20.7 1.1 0.014 13.5 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KFP03452.1 - 0.00024 20.8 3.4 0.037 13.7 0.1 3.3 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region RRM_1 PF00076.17 KFP03453.1 - 8.6e-11 41.3 0.0 1.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03453.1 - 7e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_assoc PF14363.1 KFP03453.1 - 0.021 14.8 1.2 0.13 12.3 0.2 2.1 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA RRM_5 PF13893.1 KFP03453.1 - 0.084 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup153 PF08604.5 KFP03454.1 - 1.2e-183 611.5 48.3 1.2e-183 611.5 33.5 4.9 4 2 2 6 6 6 1 Nucleoporin Nup153-like zf-RanBP PF00641.13 KFP03454.1 - 1.2e-36 123.5 35.5 3.5e-12 45.1 1.6 4.5 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Nup_retrotrp_bd PF10599.4 KFP03454.1 - 8.5e-08 32.7 16.0 8.5e-08 32.7 11.1 11.8 5 2 4 9 9 9 1 Retro-transposon transporting motif DZR PF12773.2 KFP03454.1 - 0.78 9.6 18.9 0.098 12.4 2.6 3.5 2 1 2 4 4 4 0 Double zinc ribbon RDD PF06271.7 KFP03455.1 - 8.4e-31 106.6 5.7 1.2e-30 106.1 4.0 1.2 1 0 0 1 1 1 1 RDD family DUF655 PF04919.7 KFP03455.1 - 0.08 12.6 0.4 0.11 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF655) DUF1600 PF07667.6 KFP03455.1 - 4.6 7.3 7.8 0.33 11.0 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1600) CAP_N PF01213.14 KFP03456.1 - 8e-91 304.5 5.8 6.4e-69 232.6 2.7 2.1 2 0 0 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KFP03456.1 - 2e-67 225.4 4.2 2.7e-67 225.0 2.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KFP03456.1 - 3.3e-05 23.2 2.8 6.9e-05 22.2 1.9 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C AXH PF08517.7 KFP03457.1 - 2.4e-44 150.1 0.2 4.3e-44 149.3 0.1 1.4 1 0 0 1 1 1 1 Ataxin-1 and HBP1 module (AXH) ATXN-1_C PF12547.3 KFP03457.1 - 1.5e-21 76.0 2.6 1.5e-21 76.0 1.8 3.4 2 0 0 2 2 2 1 Capicua transcriptional repressor modulator Put_DNA-bind_N PF06971.8 KFP03457.1 - 0.039 13.7 0.2 0.084 12.6 0.1 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus IMPDH PF00478.20 KFP03458.1 - 3.8e-119 397.7 0.3 5.1e-119 397.2 0.2 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFP03458.1 - 7.2e-05 21.7 1.1 0.00012 21.0 0.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 KFP03458.1 - 0.021 14.0 2.2 0.13 11.4 0.0 2.4 3 0 0 3 3 3 0 PcrB family FERM_M PF00373.13 KFP03459.1 - 4.8e-17 62.3 2.1 1.9e-16 60.3 1.4 2.0 1 1 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFP03459.1 - 1.9e-12 47.0 0.0 5.4e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 FERM N-terminal domain zf-C3HC4_3 PF13920.1 KFP03459.1 - 2e-11 43.3 21.1 5.6e-11 41.9 14.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP03459.1 - 0.00011 22.2 22.7 0.00011 22.2 15.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FERM_C PF09380.5 KFP03459.1 - 0.00059 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Prok-RING_4 PF14447.1 KFP03459.1 - 0.023 14.2 13.2 0.054 13.0 9.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rab_eff_C PF04698.7 KFP03459.1 - 1 7.3 4.9 0.15 10.1 0.1 1.7 2 0 0 2 2 2 0 Rab effector MyRIP/melanophilin C-terminus zf-RING_2 PF13639.1 KFP03459.1 - 6.1 6.7 19.3 21 5.0 13.4 2.0 1 0 0 1 1 1 0 Ring finger domain Dysbindin PF04440.11 KFP03460.1 - 2.3e-48 163.6 10.1 4.4e-48 162.7 7.0 1.4 1 0 0 1 1 1 1 Dysbindin (Dystrobrevin binding protein 1) ARID PF01388.16 KFP03461.1 - 1.6e-27 95.2 0.0 3.9e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 KFP03461.1 - 9e-22 77.4 1.3 9.7e-21 74.1 0.4 3.0 2 1 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 KFP03461.1 - 5.4e-13 48.2 0.1 1.3e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 KFP03461.1 - 7.1e-12 45.2 6.4 2e-11 43.7 4.4 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger zf-RING_5 PF14634.1 KFP03462.1 - 5.1e-06 26.1 9.9 5.1e-06 26.1 6.9 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP03462.1 - 2.6e-05 23.9 8.9 2.6e-05 23.9 6.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFP03462.1 - 0.00025 20.6 9.8 0.00062 19.3 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFP03462.1 - 0.0016 18.0 6.4 0.0016 18.0 4.4 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFP03462.1 - 0.009 16.0 11.4 0.009 16.0 7.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFP03462.1 - 0.018 14.8 8.1 0.045 13.6 5.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger Phtf-FEM1B_bdg PF12129.3 KFP03462.1 - 0.042 13.2 4.2 0.065 12.5 2.9 1.2 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor DUF1640 PF07798.6 KFP03463.1 - 1.8e-71 239.7 12.6 2.1e-71 239.6 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.13 KFP03463.1 - 0.0097 15.6 2.7 0.038 13.7 0.2 2.5 2 1 0 2 2 2 1 Homeobox associated leucine zipper Prismane PF03063.15 KFP03463.1 - 0.1 10.9 1.9 0.12 10.7 1.3 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF4407 PF14362.1 KFP03463.1 - 0.11 11.4 3.5 0.14 11.0 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cullin_Nedd8 PF10557.4 KFP03463.1 - 1.1 9.0 9.6 0.14 11.9 2.0 2.6 2 1 1 3 3 3 0 Cullin protein neddylation domain Phage_GP20 PF06810.6 KFP03463.1 - 1.4 8.2 14.5 1.2 8.5 7.7 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 KFP03463.1 - 1.9 8.3 10.0 0.85 9.4 3.8 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 KFP03463.1 - 5 7.5 10.5 35 4.8 7.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) CLTH PF10607.4 KFP03464.1 - 3.8e-48 162.8 0.0 5.3e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KFP03464.1 - 4.6e-26 91.3 0.9 6.8e-26 90.7 0.1 1.7 2 0 0 2 2 2 1 SPRY domain LisH PF08513.6 KFP03464.1 - 3.4e-06 26.6 0.0 7.9e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 LisH SIR2 PF02146.12 KFP03465.1 - 1.1e-48 165.3 0.0 1.7e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family PNTB PF02233.11 KFP03465.1 - 0.0021 16.8 0.1 0.0072 15.1 0.0 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit Med27 PF11571.3 KFP03465.1 - 0.095 12.8 0.2 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Mediator complex subunit 27 Kinesin PF00225.18 KFP03466.1 - 8.7e-107 356.6 0.2 1.6e-106 355.8 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KFP03466.1 - 8.2e-31 106.5 0.1 1e-21 77.1 0.0 3.2 2 1 0 2 2 2 2 Kinesin protein CAP_GLY PF01302.20 KFP03466.1 - 2.5e-23 81.5 2.0 5.9e-23 80.3 1.1 1.9 2 0 0 2 2 2 1 CAP-Gly domain KIF1B PF12423.3 KFP03466.1 - 1.7e-15 56.7 0.0 4.4e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KFP03466.1 - 3.5e-05 23.8 0.1 0.00041 20.4 0.0 2.5 2 0 0 2 2 2 1 FHA domain Dynamin_N PF00350.18 KFP03466.1 - 0.02 14.7 1.6 0.19 11.5 0.0 3.1 3 0 0 3 3 3 0 Dynamin family KMP11 PF03037.11 KFP03466.1 - 0.13 12.9 6.5 0.28 11.7 0.7 2.9 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 AAA_10 PF12846.2 KFP03466.1 - 0.36 10.2 3.0 0.86 8.9 0.1 2.6 3 0 0 3 3 3 0 AAA-like domain NHL PF01436.16 KFP03467.1 - 2.7e-21 74.3 5.7 0.0001 22.0 0.1 6.3 6 0 0 6 6 6 6 NHL repeat SGL PF08450.7 KFP03467.1 - 0.074 12.4 0.0 0.89 8.8 0.0 2.5 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 KFP03467.1 - 5.8 7.3 6.0 2.1 8.7 0.7 2.9 4 0 0 4 4 4 0 PQQ-like domain TPMT PF05724.6 KFP03468.1 - 2e-68 230.1 0.0 2.3e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 KFP03468.1 - 0.0034 16.9 0.0 0.019 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Amino_oxidase PF01593.19 KFP03469.1 - 4.3e-93 312.8 0.0 2.1e-92 310.5 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase zf-CW PF07496.10 KFP03469.1 - 1.6e-12 46.9 2.2 4.9e-12 45.3 1.5 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger NAD_binding_8 PF13450.1 KFP03469.1 - 3.2e-12 46.2 0.1 7.7e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFP03469.1 - 2.3e-10 39.9 0.1 2.6e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFP03469.1 - 6.8e-08 32.8 0.4 2.9e-05 24.3 0.1 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFP03469.1 - 6.9e-08 31.8 0.1 1.9e-07 30.4 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KFP03469.1 - 3.4e-07 30.5 1.6 0.00085 19.4 0.4 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFP03469.1 - 8.7e-07 27.7 0.9 5.8e-05 21.7 0.3 2.9 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFP03469.1 - 4.8e-06 26.6 0.7 6.9e-05 22.8 0.4 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFP03469.1 - 7.6e-06 25.0 0.7 5.4e-05 22.2 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain SWIRM PF04433.12 KFP03469.1 - 9.1e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain FAD_binding_3 PF01494.14 KFP03469.1 - 2.5e-05 23.5 0.2 0.00023 20.3 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KFP03469.1 - 7.4e-05 22.5 0.7 0.092 12.5 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFP03469.1 - 0.00016 20.7 0.1 0.0026 16.7 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 KFP03469.1 - 0.00026 20.2 0.1 0.00078 18.6 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-RING_2 PF13639.1 KFP03469.1 - 0.0017 18.1 4.0 0.0052 16.5 2.8 1.9 1 0 0 1 1 1 1 Ring finger domain FAD_oxidored PF12831.2 KFP03469.1 - 0.0032 16.6 0.1 0.0058 15.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KFP03469.1 - 0.0049 15.7 0.5 0.0081 15.0 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KFP03469.1 - 0.0086 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.7 KFP03469.1 - 0.012 15.0 0.2 0.02 14.2 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 KFP03469.1 - 0.02 15.1 2.4 0.03 14.5 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding YjeF_N PF03853.10 KFP03469.1 - 0.071 12.7 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus zf-C3HC4 PF00097.20 KFP03469.1 - 0.082 12.5 4.0 0.32 10.6 2.7 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Shikimate_DH PF01488.15 KFP03469.1 - 0.099 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DEK_C PF08766.6 KFP03470.1 - 6.7e-19 67.4 1.1 1.3e-18 66.4 0.8 1.6 1 0 0 1 1 1 1 DEK C terminal domain SAP PF02037.22 KFP03470.1 - 4.7e-06 25.9 1.4 1.5e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 SAP domain eIF-3c_N PF05470.7 KFP03470.1 - 0.69 7.9 26.8 0.41 8.6 3.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MIP-T3 PF10243.4 KFP03470.1 - 3.5 6.0 55.1 0.19 10.1 20.4 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 IBR PF01485.16 KFP03471.1 - 1.1e-18 66.8 20.7 1.2e-12 47.4 5.1 4.9 4 1 1 5 5 5 2 IBR domain zf-RING_2 PF13639.1 KFP03471.1 - 0.0002 21.1 54.2 0.0015 18.2 9.5 4.4 3 1 1 4 4 4 3 Ring finger domain LRR19-TM PF15176.1 KFP03471.1 - 0.72 9.5 4.4 0.15 11.7 0.4 1.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain HLH PF00010.21 KFP03473.1 - 3.8e-14 52.0 0.0 7e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RAMP PF04901.8 KFP03474.1 - 6.1e-45 151.6 2.3 6.9e-45 151.4 1.6 1.0 1 0 0 1 1 1 1 Receptor activity modifying family Guanylate_cyc PF00211.15 KFP03477.1 - 3.3e-130 430.7 0.4 1.1e-66 223.6 0.1 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFP03477.1 - 0.018 14.2 0.9 2.9 7.0 0.1 2.5 2 0 0 2 2 2 0 Heme NO binding associated DUF1053 PF06327.9 KFP03477.1 - 0.099 12.9 0.4 0.23 11.8 0.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) Thyroglobulin_1 PF00086.13 KFP03479.1 - 6.1e-18 63.9 4.1 1e-17 63.2 2.8 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat IGFBP PF00219.13 KFP03479.1 - 0.00014 22.3 11.1 0.00014 22.3 7.7 2.5 2 0 0 2 2 2 1 Insulin-like growth factor binding protein 7tm_4 PF13853.1 KFP03480.1 - 2.8e-52 176.3 8.1 2.8e-52 176.3 5.6 2.1 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP03480.1 - 4.6e-28 98.0 8.9 6.3e-28 97.6 6.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP03480.1 - 0.0019 17.4 8.6 0.0033 16.6 5.6 1.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx zf-H2C2_2 PF13465.1 KFP03481.1 - 1.5e-53 176.5 74.2 1.5e-09 37.6 0.4 8.8 9 0 0 9 9 8 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03481.1 - 1.8e-43 144.2 67.0 6.7e-06 26.1 2.2 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03481.1 - 3.2e-23 80.3 62.6 0.00029 20.9 1.3 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP03481.1 - 6e-17 60.9 45.5 0.0046 16.7 0.0 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP03481.1 - 1.1e-12 47.7 32.7 0.011 15.8 0.4 8.2 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFP03481.1 - 1e-10 41.3 38.6 0.025 14.5 2.6 8.2 4 2 3 7 7 7 5 Zinc ribbon domain XPA_N PF01286.13 KFP03481.1 - 5.7e-08 32.2 19.8 0.58 9.8 0.0 7.9 8 0 0 8 8 8 2 XPA protein N-terminal zf-RING_3 PF14369.1 KFP03481.1 - 1.5e-07 31.2 20.7 0.051 13.5 0.1 7.2 7 0 0 7 7 7 2 zinc-finger zf-Di19 PF05605.7 KFP03481.1 - 8.6e-06 25.7 11.6 0.0011 19.0 1.6 6.3 2 1 2 6 6 6 2 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.1 KFP03481.1 - 3.4e-05 23.3 21.9 0.12 12.0 0.0 7.0 7 1 1 8 8 8 2 Probable zinc-binding domain zf-LYAR PF08790.6 KFP03481.1 - 5.1e-05 22.8 26.0 1.6 8.5 0.1 8.1 8 0 0 8 8 8 1 LYAR-type C2HC zinc finger C1_3 PF07649.7 KFP03481.1 - 0.0011 18.9 21.1 5.6 7.0 0.0 6.9 7 0 0 7 7 7 0 C1-like domain zf-HIT PF04438.11 KFP03481.1 - 0.0031 17.1 31.5 0.69 9.6 0.2 7.1 7 0 0 7 7 7 2 HIT zinc finger FYDLN_acid PF09538.5 KFP03481.1 - 0.0048 17.4 15.1 6.4 7.4 0.4 6.4 1 1 3 5 5 5 0 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.8 KFP03481.1 - 0.0067 15.8 26.1 7.5 6.1 0.1 7.8 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 KFP03481.1 - 0.0084 15.9 27.0 97 2.9 10.6 5.0 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KFP03481.1 - 0.014 14.5 32.7 0.64 9.2 0.1 7.5 8 0 0 8 8 8 0 zinc-ribbon domain TerY-C PF15616.1 KFP03481.1 - 0.03 14.2 0.4 0.03 14.2 0.3 3.3 1 1 2 3 3 3 0 TerY-C metal binding domain GAGA PF09237.6 KFP03481.1 - 0.035 13.6 7.7 2.1 8.0 0.1 3.5 1 1 2 3 3 3 0 GAGA factor DUF2039 PF10217.4 KFP03481.1 - 0.04 13.9 0.5 0.04 13.9 0.3 3.9 1 1 3 4 4 3 0 Uncharacterized conserved protein (DUF2039) zf-C2HC_2 PF13913.1 KFP03481.1 - 0.083 12.5 0.1 0.083 12.5 0.1 6.6 7 0 0 7 7 6 0 zinc-finger of a C2HC-type TFIIS_C PF01096.13 KFP03481.1 - 0.085 12.4 38.1 2.9 7.6 0.4 7.6 7 2 0 7 7 7 0 Transcription factor S-II (TFIIS) HNH PF01844.18 KFP03481.1 - 0.094 12.6 36.1 2.9 7.8 0.8 7.6 8 0 0 8 8 8 0 HNH endonuclease HypA PF01155.14 KFP03481.1 - 0.096 12.3 23.0 3.1 7.5 0.7 4.7 1 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF2256 PF10013.4 KFP03481.1 - 0.12 12.1 33.3 0.39 10.5 0.1 7.4 6 2 2 8 8 7 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_4 PF07975.7 KFP03481.1 - 0.13 12.3 29.3 9.9 6.2 0.3 6.3 2 1 4 6 6 6 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 KFP03481.1 - 0.29 10.9 46.4 0.14 12.0 4.2 6.9 3 2 4 7 7 7 0 Transposase zinc-ribbon domain CpXC PF14353.1 KFP03481.1 - 0.31 11.0 25.4 23 4.9 1.3 6.8 4 3 2 6 6 6 0 CpXC protein OGG_N PF07934.7 KFP03481.1 - 0.42 10.6 3.2 13 5.8 0.3 3.1 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain YhfH PF14149.1 KFP03481.1 - 0.49 10.2 27.7 12 5.8 0.0 7.4 8 0 0 8 8 8 0 YhfH-like protein DUF329 PF03884.9 KFP03481.1 - 0.62 9.6 23.8 5 6.7 0.1 7.1 7 1 0 7 7 7 0 Domain of unknown function (DUF329) zf-IS66 PF13005.2 KFP03481.1 - 0.86 9.6 18.8 7.6 6.5 0.0 6.7 7 0 0 7 7 7 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_2 PF13240.1 KFP03481.1 - 0.97 9.0 42.2 0.97 9.0 0.3 7.6 7 1 0 7 7 7 0 zinc-ribbon domain zf-ISL3 PF14690.1 KFP03481.1 - 1.3 9.0 29.9 2.7 8.0 0.2 7.0 7 0 0 7 7 7 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Elf1 PF05129.8 KFP03481.1 - 1.4 8.6 20.0 1.1 8.9 0.4 4.9 1 1 6 7 7 7 0 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.5 KFP03481.1 - 2.5 7.6 33.0 4.2 6.9 0.3 7.3 8 0 0 8 8 7 0 A2L zinc ribbon domain Pou PF00157.12 KFP03482.1 - 1e-24 85.9 3.0 1.5e-16 59.7 0.0 3.2 4 0 0 4 4 4 2 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFP03482.1 - 8.8e-18 63.6 0.9 8.8e-18 63.6 0.6 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFP03482.1 - 0.014 15.1 0.0 0.7 9.6 0.0 2.6 2 0 0 2 2 2 0 Homeobox KN domain DUF4175 PF13779.1 KFP03482.1 - 0.35 8.5 34.5 0.59 7.7 23.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GAGA_bind PF06217.7 KFP03482.1 - 9.4 6.1 20.3 1.8 8.4 10.9 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Yae1_N PF09811.4 KFP03483.1 - 2.7e-13 49.1 1.9 4.2e-13 48.5 1.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2385 PF09539.5 KFP03483.1 - 0.058 13.7 0.0 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Ras PF00071.17 KFP03484.1 - 1.4e-55 187.1 0.3 1.7e-55 186.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP03484.1 - 6.7e-15 55.6 0.1 1.6e-14 54.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFP03484.1 - 1.7e-10 40.4 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP03484.1 - 1.7e-05 24.3 0.1 7.2e-05 22.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP03484.1 - 0.0021 17.9 0.0 0.0039 17.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP03484.1 - 0.0041 16.3 0.1 0.15 11.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFP03484.1 - 0.0058 16.0 0.2 0.018 14.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 KFP03484.1 - 0.015 14.3 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Septin ArgK PF03308.11 KFP03484.1 - 0.09 11.5 0.4 0.97 8.1 0.2 2.0 2 0 0 2 2 2 0 ArgK protein CoA_transf_3 PF02515.12 KFP03485.1 - 6.7e-53 178.7 0.1 7.8e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III LRR_8 PF13855.1 KFP03486.1 - 6.1e-20 70.7 18.4 2.3e-12 46.4 3.2 2.7 1 1 1 2 2 2 2 Leucine rich repeat GPS PF01825.16 KFP03486.1 - 5.7e-09 35.9 3.9 1e-08 35.1 0.0 3.2 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain I-set PF07679.11 KFP03486.1 - 1.8e-06 27.7 0.0 4.6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.2 KFP03486.1 - 1.1e-05 24.8 9.5 0.00035 20.1 1.1 2.6 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) HRM PF02793.17 KFP03486.1 - 0.00026 20.9 0.8 0.00068 19.5 0.5 1.8 1 0 0 1 1 1 1 Hormone receptor domain LRR_1 PF00560.28 KFP03486.1 - 0.00069 19.2 7.7 0.29 11.3 0.1 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.1 KFP03486.1 - 0.098 12.2 0.7 0.22 11.0 0.5 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.1 KFP03486.1 - 6.3 7.1 7.3 4.6 7.6 0.3 3.2 1 1 1 2 2 2 0 Leucine Rich repeat LRR_7 PF13504.1 KFP03486.1 - 9.8 6.8 6.4 18 6.1 0.5 3.5 3 0 0 3 3 3 0 Leucine rich repeat EF-hand_7 PF13499.1 KFP03487.1 - 6.5e-23 80.6 0.8 7.1e-16 58.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP03487.1 - 3.7e-22 75.8 8.4 3.4e-08 32.2 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFP03487.1 - 9.4e-19 65.5 5.4 4e-06 26.2 0.1 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KFP03487.1 - 2.7e-17 61.2 2.6 2.2e-05 23.5 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KFP03487.1 - 2.4e-14 52.6 10.1 5.7e-06 25.8 1.1 4.2 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP03487.1 - 6.7e-09 35.7 1.4 1e-05 25.5 0.2 3.3 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFP03487.1 - 0.00013 21.6 2.7 0.0071 16.0 0.2 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFP03487.1 - 0.0063 16.4 0.5 1.8 8.5 0.0 3.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_2 PF09068.6 KFP03487.1 - 0.0093 16.0 0.1 3.1 7.9 0.0 2.9 2 1 0 2 2 2 1 EF hand S10_plectin PF03501.10 KFP03487.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Plectin/S10 domain ParcG PF10274.4 KFP03488.1 - 1.1e-47 162.3 0.0 1.4e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein HEAT_EZ PF13513.1 KFP03488.1 - 0.0024 18.3 0.7 0.033 14.7 0.1 2.3 1 1 1 2 2 2 1 HEAT-like repeat LRR_8 PF13855.1 KFP03489.1 - 2.3e-83 273.8 79.6 6.9e-14 51.3 0.0 10.3 4 4 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 KFP03489.1 - 1.5e-50 168.0 45.5 2.8e-07 29.9 0.4 10.8 9 1 1 10 10 10 10 Leucine Rich repeats (2 copies) EGF PF00008.22 KFP03489.1 - 1.9e-28 97.9 91.9 8.2e-09 35.2 5.4 7.7 8 0 0 8 8 6 5 EGF-like domain LRR_1 PF00560.28 KFP03489.1 - 6.8e-25 83.2 49.3 0.14 12.3 0.0 19.3 20 0 0 20 20 20 8 Leucine Rich Repeat LRRNT PF01462.13 KFP03489.1 - 7.1e-21 73.1 38.4 3e-08 32.9 2.2 6.8 6 0 0 6 6 6 3 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.18 KFP03489.1 - 7.6e-18 64.7 0.0 1.3e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 KFP03489.1 - 2.1e-15 56.9 0.0 4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain LRR_9 PF14580.1 KFP03489.1 - 5.9e-15 55.2 17.3 0.00047 19.7 0.2 5.3 4 1 1 5 5 5 5 Leucine-rich repeat LRRCT PF01463.19 KFP03489.1 - 2.1e-14 52.2 3.6 0.012 15.7 0.0 6.5 5 0 0 5 5 5 4 Leucine rich repeat C-terminal domain hEGF PF12661.2 KFP03489.1 - 3.9e-07 29.7 57.4 0.033 14.2 1.6 8.0 8 0 0 8 8 6 5 Human growth factor-like EGF FXa_inhibition PF14670.1 KFP03489.1 - 0.00066 19.7 4.1 0.00066 19.7 2.9 7.0 4 2 2 6 6 5 3 Coagulation Factor Xa inhibitory site LRR_6 PF13516.1 KFP03489.1 - 0.075 13.1 0.0 0.17 12.0 0.0 15.2 15 3 4 19 19 17 0 Leucine Rich repeat RFX_DNA_binding PF02257.10 KFP03491.1 - 3.1e-39 133.0 0.2 7.7e-39 131.7 0.1 1.8 2 0 0 2 2 2 1 RFX DNA-binding domain RFX1_trans_act PF04589.8 KFP03491.1 - 8.5e-24 84.0 11.7 8.5e-24 84.0 8.1 2.0 2 0 0 2 2 2 1 RFX1 transcription activation region Pox_D5 PF03288.11 KFP03491.1 - 0.026 14.7 0.1 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus D5 protein-like RVT_1 PF00078.22 KFP03492.1 - 5.8e-19 68.2 0.1 1.2e-18 67.2 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cadherin PF00028.12 KFP03497.1 - 6.5e-103 337.2 11.4 6.6e-20 71.1 0.1 7.4 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 KFP03497.1 - 7.9e-88 293.8 0.3 2.2e-87 292.3 0.2 1.7 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 KFP03497.1 - 3.6e-19 68.1 0.1 1.8e-08 33.8 0.0 6.2 6 0 0 6 6 6 3 Cadherin-like RCR PF12273.3 KFP03497.1 - 0.0048 17.4 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.1 KFP03497.1 - 0.013 15.8 0.2 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KFP03497.1 - 0.037 12.2 0.0 0.097 10.9 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E He_PIG PF05345.7 KFP03497.1 - 0.069 13.1 9.9 22 5.1 0.0 5.7 5 1 0 5 5 5 0 Putative Ig domain SHR3_chaperone PF08229.6 KFP03497.1 - 0.085 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 CD34_antigen PF06365.7 KFP03497.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Shisa PF13908.1 KFP03497.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator BLVR PF06375.6 KFP03497.1 - 7.3 6.3 9.0 0.29 10.9 1.7 2.0 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Yae1_N PF09811.4 KFP03499.1 - 3.5e-12 45.6 40.9 7.5 6.1 23.9 4.4 2 1 0 2 2 2 2 Essential protein Yae1, N terminal IRK PF01007.15 KFP03500.1 - 1.7e-142 474.2 0.5 2e-142 473.9 0.3 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP03500.1 - 0.0012 18.5 2.6 0.0026 17.4 1.8 1.6 1 1 0 1 1 1 1 Ion channel Ets PF00178.17 KFP03501.1 - 4.5e-40 135.6 0.8 8.2e-40 134.8 0.5 1.4 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 KFP03501.1 - 2e-26 91.5 0.0 3.6e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.12 KFP03501.1 - 0.0047 16.7 0.2 0.055 13.3 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP03501.1 - 0.13 12.4 0.5 0.34 11.0 0.4 1.7 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) Ets PF00178.17 KFP03502.1 - 5.1e-40 135.5 0.6 5.1e-40 135.5 0.4 1.9 3 0 0 3 3 3 1 Ets-domain SAM_PNT PF02198.11 KFP03502.1 - 2e-34 117.2 1.5 3.9e-34 116.2 1.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain WD40 PF00400.27 KFP03504.1 - 5.7e-53 175.0 16.9 1.8e-08 33.9 0.1 9.1 10 0 0 10 10 10 8 WD domain, G-beta repeat Bromodomain PF00439.20 KFP03504.1 - 6.9e-36 122.0 0.1 2.9e-17 62.3 0.1 2.6 2 0 0 2 2 2 2 Bromodomain eIF2A PF08662.6 KFP03504.1 - 0.0096 15.6 0.1 1 9.0 0.0 2.7 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A HMG14_17 PF01101.13 KFP03505.1 - 3.5e-21 75.7 21.5 3.8e-21 75.5 14.9 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 F-112 PF09645.5 KFP03505.1 - 0.036 13.9 1.0 0.038 13.8 0.7 1.1 1 0 0 1 1 1 0 F-112 protein DUF912 PF06024.7 KFP03505.1 - 1.3 9.1 3.3 1.4 9.0 2.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CHD5 PF04420.9 KFP03506.1 - 8.7e-45 152.2 0.8 9.6e-45 152.1 0.5 1.0 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_20 PF13942.1 KFP03506.1 - 0.05 13.1 1.3 0.064 12.7 0.9 1.2 1 0 0 1 1 1 0 YfhG lipoprotein DUF1640 PF07798.6 KFP03506.1 - 0.69 9.9 6.5 1.8 8.5 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) SH3BGR PF04908.10 KFP03508.1 - 1.3e-47 159.8 0.1 1.4e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KFP03508.1 - 0.00085 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin I-set PF07679.11 KFP03509.1 - 2.6e-15 56.0 0.0 1.2e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain C2-set_2 PF08205.7 KFP03509.1 - 2.2e-11 43.4 1.4 3.8e-08 33.1 0.1 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.1 KFP03509.1 - 1.3e-09 38.0 1.2 0.00064 19.8 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.10 KFP03509.1 - 6.5e-07 29.2 0.1 5.1e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Ig_3 PF13927.1 KFP03509.1 - 1.3e-05 25.5 5.3 0.0011 19.4 0.1 3.4 1 1 2 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFP03509.1 - 0.00022 21.2 3.6 0.0055 16.7 0.1 3.4 2 2 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP03509.1 - 0.0034 17.2 2.7 0.41 10.5 0.2 2.9 1 1 1 2 2 2 2 Immunoglobulin V-set domain Marek_A PF02124.10 KFP03509.1 - 0.0036 16.7 3.9 0.0065 15.9 2.7 1.5 1 1 0 1 1 1 1 Marek's disease glycoprotein A TMEM154 PF15102.1 KFP03509.1 - 0.0038 16.9 1.6 0.0078 15.9 1.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF1616 PF07760.6 KFP03509.1 - 0.045 12.8 1.1 0.074 12.1 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Protocadherin PF08374.6 KFP03509.1 - 0.079 12.5 2.5 0.14 11.7 1.7 1.4 1 0 0 1 1 1 0 Protocadherin DUF872 PF05915.7 KFP03509.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) PIRT PF15099.1 KFP03509.1 - 0.11 11.6 6.4 0.45 9.7 1.6 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Shisa PF13908.1 KFP03509.1 - 0.73 9.9 3.0 1.6 8.9 2.1 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IQ PF00612.22 KFP03510.1 - 0.013 15.0 0.6 0.018 14.6 0.4 1.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ca_chan_IQ PF08763.6 KFP03510.1 - 0.087 12.0 0.2 0.087 12.0 0.2 1.5 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain I-set PF07679.11 KFP03511.1 - 3e-105 344.2 5.4 5.7e-14 51.7 0.0 10.8 12 0 0 12 12 12 8 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP03511.1 - 5.7e-82 269.9 7.1 1.4e-11 44.3 0.0 9.6 9 0 0 9 9 9 9 Immunoglobulin domain fn3 PF00041.16 KFP03511.1 - 6.5e-69 228.1 14.0 8.6e-14 51.4 0.0 8.1 8 0 0 8 8 8 6 Fibronectin type III domain Ig_3 PF13927.1 KFP03511.1 - 9.5e-61 202.1 33.2 4.3e-10 39.9 0.9 11.1 12 0 0 12 12 11 7 Immunoglobulin domain ig PF00047.20 KFP03511.1 - 4.9e-52 173.9 8.4 6.5e-07 29.3 0.0 9.4 8 1 0 8 8 8 8 Immunoglobulin domain V-set PF07686.12 KFP03511.1 - 1.6e-36 124.6 13.5 3.1e-06 27.0 0.0 9.9 9 3 0 9 9 9 7 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP03511.1 - 6.7e-15 54.7 5.8 2 8.3 0.1 8.8 8 0 0 8 8 8 5 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFP03511.1 - 3.3e-07 30.2 3.0 0.36 10.8 0.0 6.8 8 0 0 8 8 8 2 Immunoglobulin C1-set domain Interfer-bind PF09294.5 KFP03511.1 - 3e-06 27.2 2.1 0.28 11.2 0.0 5.1 6 0 0 6 6 6 2 Interferon-alpha/beta receptor, fibronectin type III Sp38 PF07354.7 KFP03511.1 - 8.4e-05 21.3 0.3 0.39 9.3 0.0 5.0 5 0 0 5 5 5 1 Zona-pellucida-binding protein (Sp38) Receptor_2B4 PF11465.3 KFP03511.1 - 0.00011 22.0 0.0 7.8 6.4 0.0 5.3 4 0 0 4 4 4 1 Natural killer cell receptor 2B4 V-set_CD47 PF08204.6 KFP03511.1 - 0.00012 21.8 0.7 1.4 8.6 0.0 5.8 7 0 0 7 7 7 1 CD47 immunoglobulin-like domain ChitinaseA_N PF08329.5 KFP03511.1 - 0.0023 17.6 0.0 0.1 12.3 0.0 3.1 2 1 0 2 2 2 1 Chitinase A, N-terminal domain DUF4446 PF14584.1 KFP03511.1 - 0.11 12.2 2.5 0.11 12.2 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Ig_2 PF13895.1 KFP03512.1 - 9e-06 25.7 0.1 0.00027 20.9 0.0 2.4 1 1 1 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFP03512.1 - 0.0002 21.7 0.5 0.00045 20.6 0.1 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Asp PF00026.18 KFP03513.1 - 1.4e-38 132.9 0.4 3.8e-38 131.5 0.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KFP03513.1 - 1.7e-13 50.4 0.0 2.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Dynamin_M PF01031.15 KFP03515.1 - 6.2e-78 261.5 10.4 9e-78 261.0 7.2 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KFP03515.1 - 1.7e-41 141.8 0.9 4.3e-41 140.5 0.0 2.2 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 KFP03515.1 - 7.5e-12 44.9 0.1 7.5e-12 44.9 0.0 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFP03515.1 - 1.2e-06 28.4 0.0 3.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFP03515.1 - 0.0027 18.1 0.1 0.021 15.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 KFP03515.1 - 0.005 17.1 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 KFP03515.1 - 0.0087 15.5 0.1 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KFP03515.1 - 0.011 15.6 0.2 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFP03515.1 - 0.016 15.1 6.0 0.13 12.2 0.0 3.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KFP03515.1 - 0.07 13.0 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KFP03515.1 - 0.076 12.2 0.1 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Trypsin PF00089.21 KFP03516.1 - 4.5e-53 180.0 0.2 7.2e-53 179.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 KFP03516.1 - 4.2e-29 100.6 0.0 9.2e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 KFP03516.1 - 7.3e-08 32.0 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.13 KFP03516.1 - 2.7e-06 27.1 5.2 7.6e-06 25.7 3.6 1.8 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A SRCR PF00530.13 KFP03516.1 - 5.4e-05 23.4 0.1 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Trypsin_2 PF13365.1 KFP03516.1 - 0.0019 18.1 0.0 0.0045 16.9 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Hepsin-SRCR PF09272.5 KFP03516.1 - 0.012 15.8 0.1 0.055 13.6 0.0 2.0 2 0 0 2 2 2 0 Hepsin, SRCR zf-C2H2 PF00096.21 KFP03517.1 - 3.2e-51 168.6 141.0 6.9e-06 26.0 0.9 18.0 18 0 0 18 18 18 17 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03517.1 - 1.3e-43 144.1 106.3 0.00018 21.5 0.3 17.4 17 0 0 17 17 17 15 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP03517.1 - 2.3e-35 119.1 112.3 3.5e-05 23.8 0.3 18.0 18 0 0 18 18 18 11 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP03517.1 - 1.9e-18 66.0 97.8 0.0029 17.6 0.1 17.3 18 0 0 18 18 18 10 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP03517.1 - 5.6e-15 54.9 103.6 0.035 14.3 0.2 17.4 17 0 0 17 17 17 11 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP03517.1 - 6.5e-05 22.6 103.8 0.014 15.2 1.0 16.9 17 1 1 18 18 18 7 C2H2-type zinc finger SET PF00856.23 KFP03517.1 - 0.0019 18.5 0.9 0.017 15.4 0.0 2.8 3 0 0 3 3 3 1 SET domain zf-C2HC_2 PF13913.1 KFP03517.1 - 0.051 13.2 0.2 0.051 13.2 0.1 11.1 11 0 0 11 11 11 0 zinc-finger of a C2HC-type C2 PF00168.25 KFP03518.1 - 1.6e-08 34.2 0.0 8.6e-08 31.9 0.0 2.2 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 KFP03518.1 - 0.034 13.6 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 CEP76 C2 domain BTB PF00651.26 KFP03519.1 - 3.2e-26 91.5 0.1 6.1e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFP03519.1 - 7.6e-14 51.1 78.4 0.00092 19.4 1.2 9.3 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03519.1 - 7.7e-12 44.6 73.6 0.0062 16.7 0.1 9.5 8 1 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP03519.1 - 1.3e-05 25.1 65.6 0.0026 17.9 3.2 10.7 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP03519.1 - 0.0012 18.8 49.4 0.3 11.2 1.7 9.2 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 KFP03519.1 - 0.8 9.6 9.1 2 8.3 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_6 PF13912.1 KFP03519.1 - 3.6 7.6 47.1 0.48 10.4 0.6 9.2 10 0 0 10 10 10 0 C2H2-type zinc finger zf-met PF12874.2 KFP03519.1 - 9.6 6.5 43.2 0.09 13.0 1.6 7.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Zona_pellucida PF00100.18 KFP03520.1 - 1.4e-37 129.6 4.5 3.8e-37 128.1 3.2 1.8 1 0 0 1 1 1 1 Zona pellucida-like domain SEA PF01390.15 KFP03520.1 - 1.4e-20 72.9 3.3 1.4e-09 37.6 0.1 2.7 2 0 0 2 2 2 2 SEA domain EGF_CA PF07645.10 KFP03520.1 - 3.5e-17 62.1 42.3 5.2e-08 32.7 4.8 4.7 4 0 0 4 4 4 3 Calcium-binding EGF domain EMI PF07546.8 KFP03520.1 - 1.1e-07 32.1 6.7 1.1e-07 32.1 4.7 3.5 2 0 0 2 2 2 1 EMI domain WAP PF00095.16 KFP03520.1 - 1.9e-06 27.6 8.5 1.9e-06 27.6 5.9 3.3 3 0 0 3 3 3 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' EGF_3 PF12947.2 KFP03520.1 - 1.9e-05 24.5 6.6 1.9e-05 24.5 4.6 4.1 4 0 0 4 4 4 2 EGF domain fn3 PF00041.16 KFP03520.1 - 0.029 14.5 0.1 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Fibronectin type III domain ABC2_membrane PF01061.19 KFP03521.1 - 1.9e-44 151.3 25.8 3.9e-44 150.3 17.9 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFP03521.1 - 5.2e-30 104.5 0.0 8.5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFP03521.1 - 1.1e-10 41.9 0.0 4.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFP03521.1 - 5.1e-07 29.1 0.0 1.9e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KFP03521.1 - 8.1e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFP03521.1 - 0.0022 18.7 0.0 0.0057 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP03521.1 - 0.0025 17.8 0.1 0.0056 16.6 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.1 KFP03521.1 - 0.0031 17.0 0.5 0.007 15.8 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KFP03521.1 - 0.011 15.1 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 KFP03521.1 - 0.016 15.3 0.1 0.054 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KFP03521.1 - 0.03 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KFP03521.1 - 0.03 14.6 0.2 0.064 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFP03521.1 - 0.066 12.6 0.4 0.18 11.2 0.3 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFP03521.1 - 0.071 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KFP03521.1 - 0.094 12.6 0.5 2.5 8.0 0.1 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KFP03521.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFP03521.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 KFP03521.1 - 0.13 10.7 0.0 2.6 6.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFP03521.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KFP03521.1 - 0.2 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein ABC2_membrane_3 PF12698.2 KFP03521.1 - 0.26 10.2 28.5 0.03 13.3 15.8 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein Trefoil PF00088.13 KFP03522.1 - 1e-31 108.2 21.9 2.8e-16 58.8 5.4 2.2 2 0 0 2 2 2 2 Trefoil (P-type) domain Trypsin PF00089.21 KFP03523.1 - 1.5e-72 243.8 0.4 2e-72 243.3 0.3 1.2 1 0 0 1 1 1 1 Trypsin SRCR_2 PF15494.1 KFP03523.1 - 6.2e-26 90.4 1.1 1.3e-25 89.5 0.8 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR PF00530.13 KFP03523.1 - 1.8e-08 34.5 1.3 3.6e-08 33.6 0.2 2.1 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF1986 PF09342.6 KFP03523.1 - 9.9e-07 28.3 0.1 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Ldl_recept_a PF00057.13 KFP03523.1 - 2.8e-06 27.1 7.0 6.9e-06 25.8 4.9 1.7 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A Hepsin-SRCR PF09272.5 KFP03523.1 - 0.00027 21.1 0.7 0.00072 19.7 0.5 1.7 1 0 0 1 1 1 1 Hepsin, SRCR Trypsin_2 PF13365.1 KFP03523.1 - 0.0022 17.9 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain His_Phos_1 PF00300.17 KFP03524.1 - 5.7e-23 81.7 0.0 3.1e-22 79.3 0.0 2.2 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.1 KFP03524.1 - 1.5e-13 50.1 0.0 3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP03524.1 - 4.4e-05 22.8 0.0 0.00011 21.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP03524.1 - 7.9e-05 21.9 0.0 0.00016 20.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain UBA PF00627.26 KFP03524.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain 2_5_RNA_ligase2 PF13563.1 KFP03524.1 - 0.031 13.9 0.5 0.31 10.7 0.4 2.1 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KFP03524.1 - 0.13 12.2 0.1 25 4.9 0.0 2.8 2 0 0 2 2 2 0 LigT like Phosphoesterase GHMP_kinases_C PF08544.8 KFP03524.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal MORN PF02493.15 KFP03525.1 - 3.9e-36 120.6 43.4 1.6e-10 40.0 1.3 7.4 7 0 0 7 7 7 7 MORN repeat MFS_1 PF07690.11 KFP03526.1 - 1.3e-33 116.2 38.1 1.7e-28 99.3 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2985 PF11204.3 KFP03526.1 - 0.01 15.5 0.8 0.74 9.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) PDEase_I PF00233.14 KFP03527.1 - 1.6e-66 224.4 1.9 1.6e-66 224.4 1.3 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Histone_HNS PF00816.16 KFP03527.1 - 0.12 12.8 0.4 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 H-NS histone family MATH PF00917.21 KFP03528.1 - 4.1e-24 85.1 0.0 7.6e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 MATH domain zf-TRAF PF02176.13 KFP03528.1 - 5.8e-06 26.5 6.1 5.8e-06 26.5 4.2 3.6 4 0 0 4 4 4 2 TRAF-type zinc finger zf-C3HC4 PF00097.20 KFP03528.1 - 0.0002 20.9 10.4 0.0002 20.9 7.2 3.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF641 PF04859.7 KFP03528.1 - 0.15 11.8 0.5 1.1 8.9 0.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PHD PF00628.24 KFP03529.1 - 6.4e-14 51.3 18.1 2.8e-08 33.3 1.2 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 KFP03529.1 - 6.5e-05 22.1 3.8 6.5e-05 22.1 2.6 3.8 3 2 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 KFP03529.1 - 0.00073 19.2 0.7 0.00073 19.2 0.5 3.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 DUF4537 PF15057.1 KFP03529.1 - 0.0033 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) C1_1 PF00130.17 KFP03529.1 - 0.027 14.2 0.5 0.027 14.2 0.3 4.0 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 KFP03529.1 - 6.4 6.9 11.0 4.4 7.4 0.4 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger Mtf2_C PF14061.1 KFP03530.1 - 1.4e-29 101.7 0.1 2.3e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Chromo PF00385.19 KFP03530.1 - 0.05 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain CutA1 PF03091.10 KFP03531.1 - 4.9e-30 103.2 0.1 5.7e-30 102.9 0.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Proteasom_PSMB PF10508.4 KFP03532.1 - 3.2e-166 553.5 0.0 3.6e-166 553.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 KFP03532.1 - 9.7e-05 22.5 0.2 0.17 12.1 0.0 3.7 2 2 1 3 3 3 1 HEAT repeats V-ATPase_H_C PF11698.3 KFP03532.1 - 0.0082 16.0 0.1 3.9 7.4 0.0 3.2 3 0 0 3 3 3 1 V-ATPase subunit H Neurochondrin PF05536.6 KFP03532.1 - 0.015 13.6 0.5 0.46 8.7 0.0 2.5 1 1 0 2 2 2 0 Neurochondrin CLAMP PF14769.1 KFP03532.1 - 0.026 14.6 0.0 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DUF3554 PF12074.3 KFP03532.1 - 0.045 13.1 0.2 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3554) Galactosyl_T PF01762.16 KFP03533.1 - 4.3e-36 124.3 0.0 5.4e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 KFP03533.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 Fringe-like PriCT_2 PF08707.6 KFP03533.1 - 0.098 12.5 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) CH PF00307.26 KFP03534.1 - 2.4e-33 114.4 0.3 6.2e-33 113.0 0.2 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP03534.1 - 2.6e-32 110.2 0.2 6e-32 109.1 0.1 1.7 1 0 0 1 1 1 1 CAMSAP CH domain CAMSAP_CKK PF08683.6 KFP03534.1 - 3e-11 43.0 0.1 6.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated UBA PF00627.26 KFP03535.1 - 1.8e-16 59.3 0.7 6.1e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain UBA_3 PF09288.5 KFP03535.1 - 0.0056 16.2 0.1 1.1 8.9 0.0 3.0 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain HBS1_N PF08938.5 KFP03535.1 - 0.14 12.3 1.6 0.83 9.8 0.0 2.8 3 0 0 3 3 3 0 HBS1 N-terminus BTB PF00651.26 KFP03536.1 - 2.3e-23 82.2 0.0 4.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BEN PF10523.4 KFP03536.1 - 2.3e-10 40.3 1.0 8.7e-10 38.5 0.1 2.3 3 0 0 3 3 3 1 BEN domain LIM PF00412.17 KFP03537.1 - 8.3e-15 54.6 8.3 1.2e-14 54.0 5.7 1.3 1 0 0 1 1 1 1 LIM domain Homeobox PF00046.24 KFP03537.1 - 5e-14 51.6 0.3 1e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP03537.1 - 0.00032 20.3 0.0 0.00079 19.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Evr1_Alr PF04777.8 KFP03538.1 - 2.4e-26 91.4 0.5 6.8e-26 89.9 0.3 1.8 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.15 KFP03538.1 - 0.0067 16.0 0.0 0.088 12.4 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin Zn-ribbon_8 PF09723.5 KFP03538.1 - 0.23 11.4 1.9 7.8 6.5 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain FlhE PF06366.8 KFP03540.1 - 0.04 13.7 0.3 0.064 13.1 0.2 1.4 1 1 0 1 1 1 0 Flagellar protein FlhE vATP-synt_E PF01991.13 KFP03540.1 - 6 6.0 12.6 0.92 8.7 6.0 1.6 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit GoLoco PF02188.12 KFP03541.1 - 4.9e-42 140.3 22.5 1.3e-10 40.3 1.1 4.7 4 0 0 4 4 4 4 GoLoco motif TPR_12 PF13424.1 KFP03541.1 - 9.6e-42 140.8 31.8 1.6e-09 37.5 2.1 6.1 3 2 2 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFP03541.1 - 1.9e-36 122.1 28.0 1.5e-05 24.3 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFP03541.1 - 5.5e-30 100.7 16.9 8.4e-06 25.2 0.2 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFP03541.1 - 1.2e-21 76.0 24.7 3.1e-06 26.7 0.7 6.3 4 1 2 7 7 7 6 TPR repeat TPR_2 PF07719.12 KFP03541.1 - 6.1e-21 72.5 29.7 0.0046 16.7 0.4 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFP03541.1 - 1.6e-16 58.7 23.4 0.0065 16.1 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 KFP03541.1 - 3.5e-16 58.5 15.3 0.073 13.0 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFP03541.1 - 1.8e-08 34.2 6.4 24 5.9 0.0 7.7 5 3 3 8 8 8 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 KFP03541.1 - 1.7e-06 27.7 1.1 0.18 11.6 0.0 4.6 3 3 2 5 5 5 2 Rapsyn N-terminal myristoylation and linker region TPR_16 PF13432.1 KFP03541.1 - 3.1e-06 27.7 16.3 0.15 12.7 0.1 6.4 2 2 6 8 8 8 5 Tetratricopeptide repeat TPR_4 PF07721.9 KFP03541.1 - 7.1e-06 25.9 3.8 14 6.4 0.0 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFP03541.1 - 0.00012 22.0 15.8 3 8.2 0.0 7.2 6 1 1 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP03541.1 - 0.00081 19.4 15.9 9 6.5 4.5 5.1 2 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 UreE_C PF05194.7 KFP03541.1 - 0.0032 17.5 2.0 1.3 9.1 0.1 3.8 3 2 1 4 4 4 1 UreE urease accessory protein, C-terminal domain TPR_6 PF13174.1 KFP03541.1 - 0.01 16.2 8.7 1.3e+02 3.4 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat FliJ PF02050.11 KFP03541.1 - 0.44 10.6 4.9 1.3 9.1 0.2 3.5 2 2 2 4 4 4 0 Flagellar FliJ protein zf-DNL PF05180.7 KFP03542.1 - 1.2e-25 88.9 0.2 1.5e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger CARD PF00619.16 KFP03543.1 - 2.9e-21 75.0 0.0 2.9e-21 75.0 0.0 2.8 3 0 0 3 3 3 1 Caspase recruitment domain DUF904 PF06005.7 KFP03543.1 - 0.0019 18.4 4.9 0.0019 18.4 3.4 5.6 2 1 1 3 3 3 1 Protein of unknown function (DUF904) DUF2744 PF10910.3 KFP03543.1 - 0.049 13.4 0.1 0.16 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) Orthopox_B11R PF07033.6 KFP03543.1 - 2.1 7.9 4.2 1.1 8.7 0.4 2.5 2 1 1 3 3 3 0 Orthopoxvirus B11R protein Myb_DNA-binding PF00249.26 KFP03544.1 - 7.2e-50 166.8 15.4 2.2e-14 53.2 0.7 5.8 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFP03544.1 - 1.1e-42 143.9 16.2 9.6e-14 51.2 1.0 5.8 1 1 4 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 KFP03544.1 - 0.0034 17.1 0.3 1.1 9.0 0.1 3.4 2 1 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.3 KFP03544.1 - 0.016 15.0 2.6 0.083 12.7 0.0 3.0 2 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 KFP03544.1 - 0.087 12.7 16.1 12 5.8 0.1 6.5 4 1 1 6 6 6 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFP03544.1 - 4.1 7.5 25.0 3.6 7.7 2.4 6.1 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain ERM PF00769.14 KFP03545.1 - 3.1e-05 23.6 15.8 3.7e-05 23.3 11.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF724 PF05266.9 KFP03545.1 - 0.007 16.0 14.5 0.011 15.3 10.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) ART PF01129.13 KFP03545.1 - 0.04 13.0 1.8 0.053 12.6 1.3 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase RP-C_C PF11800.3 KFP03545.1 - 0.09 12.4 7.1 0.11 12.1 4.9 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Tropomyosin PF00261.15 KFP03545.1 - 0.12 11.4 20.1 0.14 11.2 12.6 2.1 1 1 0 1 1 1 0 Tropomyosin DUF3781 PF12636.2 KFP03545.1 - 0.15 12.0 2.3 0.12 12.3 0.4 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3781) SIN1 PF05422.7 KFP03545.1 - 0.15 10.5 7.2 0.17 10.3 5.0 1.0 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) LNP1 PF15419.1 KFP03545.1 - 0.16 12.0 6.0 0.3 11.1 3.8 1.7 1 1 1 2 2 2 0 Leukemia NUP98 fusion partner 1 DUF2514 PF10721.4 KFP03545.1 - 0.28 10.8 11.6 0.42 10.3 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) V_ATPase_I PF01496.14 KFP03545.1 - 0.61 7.8 12.6 0.65 7.7 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.4 KFP03545.1 - 0.73 8.1 8.4 0.86 7.9 5.8 1.2 1 0 0 1 1 1 0 Peptidase S46 CENP-O PF09496.5 KFP03545.1 - 0.79 9.9 3.3 0.52 10.5 0.8 1.7 2 1 0 2 2 2 0 Cenp-O kinetochore centromere component Sipho_Gp157 PF05565.6 KFP03545.1 - 1.1 8.8 15.6 13 5.3 10.4 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 DUF4518 PF15008.1 KFP03545.1 - 1.1 8.2 8.9 1.6 7.6 6.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) PAP_central PF04928.12 KFP03545.1 - 1.2 7.9 5.0 1.4 7.7 3.5 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain GAS PF13851.1 KFP03545.1 - 1.8 7.7 23.6 64 2.6 5.4 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spore_II_R PF09551.5 KFP03545.1 - 5.4 7.0 7.3 4.4 7.3 3.4 1.9 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) Fib_alpha PF08702.5 KFP03545.1 - 5.5 7.1 17.6 5.7 7.0 0.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 KFP03545.1 - 9.7 6.5 19.5 3.2 8.1 6.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Peptidase_M16_C PF05193.16 KFP03546.1 - 1.3e-41 142.3 0.0 2.3e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFP03546.1 - 6.9e-41 139.4 0.0 1.6e-40 138.3 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2695 PF10905.3 KFP03546.1 - 0.039 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Exo_endo_phos PF03372.18 KFP03547.1 - 1.7e-20 74.0 0.3 2.5e-20 73.5 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sec16_C PF12931.2 KFP03548.1 - 1.8e-36 126.3 0.0 2.9e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KFP03548.1 - 2.7e-19 69.2 0.0 6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Ank_2 PF12796.2 KFP03549.1 - 4.2e-56 187.2 27.5 1.9e-15 56.9 0.9 3.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFP03549.1 - 3.8e-45 149.5 11.4 2.4e-08 33.3 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KFP03549.1 - 8.3e-28 95.7 9.5 7.4e-10 38.7 0.1 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP03549.1 - 1.3e-26 89.9 3.8 3.7e-05 23.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFP03549.1 - 3.5e-21 75.1 9.8 7.9e-09 35.7 0.1 4.6 2 1 4 6 6 6 4 Ankyrin repeats (many copies) EGF PF00008.22 KFP03550.1 - 7.2e-111 361.4 234.1 9.6e-10 38.2 5.4 15.3 15 0 0 15 15 15 15 EGF-like domain EGF_CA PF07645.10 KFP03550.1 - 5.1e-48 160.8 233.9 1.5e-07 31.2 6.6 15.2 8 3 7 15 15 15 15 Calcium-binding EGF domain hEGF PF12661.2 KFP03550.1 - 2.5e-26 89.8 155.5 0.0022 17.9 3.9 17.0 16 0 0 16 16 16 12 Human growth factor-like EGF EGF_2 PF07974.8 KFP03550.1 - 2.4e-24 85.1 259.9 0.0075 16.4 4.6 15.4 15 0 0 15 15 15 15 EGF-like domain EGF_3 PF12947.2 KFP03550.1 - 5.7e-10 38.9 208.3 0.0008 19.3 3.8 16.5 9 7 6 15 15 15 11 EGF domain FXa_inhibition PF14670.1 KFP03550.1 - 4.1e-09 36.3 211.1 0.31 11.1 7.6 15.7 5 3 10 15 15 15 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP03550.1 - 0.34 10.5 197.4 0.038 13.6 2.5 18.4 15 7 0 15 15 15 0 Complement Clr-like EGF-like EMI PF07546.8 KFP03551.1 - 7.7e-15 55.1 3.6 7.7e-15 55.1 2.5 2.5 2 1 0 2 2 1 1 EMI domain FXa_inhibition PF14670.1 KFP03551.1 - 8.5e-11 41.7 4.6 8.5e-11 41.7 3.2 3.1 2 1 1 3 3 3 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFP03551.1 - 2.9e-10 39.9 4.8 2.9e-10 39.9 3.3 3.2 2 1 1 3 3 3 1 Calcium-binding EGF domain cEGF PF12662.2 KFP03551.1 - 7.2e-05 22.3 0.2 7.2e-05 22.3 0.1 3.8 4 1 0 4 4 4 1 Complement Clr-like EGF-like EGF_2 PF07974.8 KFP03551.1 - 0.00016 21.7 8.2 0.00016 21.7 5.7 3.6 3 1 1 4 4 4 1 EGF-like domain EGF PF00008.22 KFP03551.1 - 0.0008 19.3 27.8 0.0017 18.2 5.9 3.2 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.2 KFP03551.1 - 0.0074 16.2 4.3 0.0074 16.2 3.0 3.5 4 0 0 4 4 3 1 Human growth factor-like EGF EGF_3 PF12947.2 KFP03551.1 - 0.0098 15.8 2.2 0.0098 15.8 1.5 3.2 3 0 0 3 3 3 1 EGF domain DUF3261 PF11659.3 KFP03551.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) Seryl_tRNA_N PF02403.17 KFP03551.1 - 0.024 14.6 0.2 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.10 KFP03551.1 - 0.089 12.6 3.9 2.5 7.9 0.8 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Uds1 PF15456.1 KFP03551.1 - 0.1 12.5 1.2 3.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Pox_A_type_inc PF04508.7 KFP03551.1 - 0.27 11.1 6.1 3.2 7.7 0.9 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TMF_DNA_bd PF12329.3 KFP03551.1 - 0.34 10.7 2.5 7.2 6.4 0.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PIP49_C PF12260.3 KFP03552.1 - 4.3e-61 205.6 0.2 4.3e-61 205.6 0.2 1.8 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 PIP49_N PF14875.1 KFP03552.1 - 1.2e-55 187.5 0.2 3e-55 186.2 0.0 1.8 2 0 0 2 2 2 1 N-term cysteine-rich ER, FAM69 EF-hand_1 PF00036.27 KFP03552.1 - 0.00089 18.4 0.6 0.0083 15.3 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KFP03552.1 - 0.0025 17.8 0.0 0.0075 16.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFP03552.1 - 0.0039 16.7 0.0 0.0088 15.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP03552.1 - 0.0041 16.3 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 EF hand Ribosomal_S2 PF00318.15 KFP03553.1 - 7.8e-47 159.2 0.4 1.2e-23 83.4 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Consortin_C PF15281.1 KFP03554.1 - 0.059 12.8 1.2 0.21 11.0 0.8 1.9 1 0 0 1 1 1 0 Consortin C-terminus OLF PF02191.11 KFP03555.1 - 1.2e-94 316.2 3.5 2.1e-94 315.4 2.4 1.4 1 0 0 1 1 1 1 Olfactomedin-like domain Noelin-1 PF12308.3 KFP03555.1 - 1.2e-48 163.0 9.7 2.7e-48 161.9 4.0 2.7 3 0 0 3 3 3 1 Neurogenesis glycoprotein Nup54 PF13874.1 KFP03555.1 - 0.0024 17.5 9.5 0.0031 17.1 6.0 1.6 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Atg14 PF10186.4 KFP03555.1 - 0.0027 16.7 8.6 0.0042 16.0 6.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFP03555.1 - 0.0032 17.0 13.3 0.0058 16.2 9.2 1.4 1 0 0 1 1 1 1 IncA protein Pox_A_type_inc PF04508.7 KFP03555.1 - 0.0096 15.6 0.6 0.037 13.8 0.4 2.0 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.7 KFP03555.1 - 0.01 15.6 2.0 0.11 12.3 0.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lipoprotein_7 PF01540.11 KFP03555.1 - 0.011 14.8 1.9 0.016 14.2 1.3 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein Reo_sigmaC PF04582.7 KFP03555.1 - 0.037 13.2 0.1 0.057 12.5 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3926 PF13080.1 KFP03555.1 - 0.077 12.5 0.6 0.16 11.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) NPV_P10 PF05531.7 KFP03555.1 - 0.087 13.0 3.3 3.5 7.9 1.9 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 KFP03555.1 - 0.091 11.2 11.6 0.0062 15.0 4.0 1.8 2 0 0 2 2 2 0 AAA domain Xpo1 PF08389.7 KFP03555.1 - 0.11 12.4 1.5 0.18 11.7 0.3 1.9 1 1 0 1 1 1 0 Exportin 1-like protein DUF1664 PF07889.7 KFP03555.1 - 0.16 11.7 8.2 2.6 7.8 2.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) FH2 PF02181.18 KFP03555.1 - 0.2 10.4 9.2 0.48 9.2 0.2 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain V_ATPase_I PF01496.14 KFP03555.1 - 0.28 8.9 6.4 0.44 8.3 4.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.20 KFP03555.1 - 0.29 11.3 10.1 0.23 11.6 3.2 2.8 1 1 1 2 2 2 0 Syntaxin MitMem_reg PF13012.1 KFP03555.1 - 0.29 11.2 8.1 1.8 8.6 4.5 2.9 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function BLOC1_2 PF10046.4 KFP03555.1 - 0.5 10.5 9.8 2.1 8.5 1.7 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 KFP03555.1 - 0.87 9.4 12.0 0.57 10.0 3.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Borrelia_REV PF03978.8 KFP03555.1 - 1.2 8.7 5.5 14 5.3 0.1 2.3 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein H-kinase_dim PF02895.9 KFP03555.1 - 1.4 9.3 7.2 42 4.5 5.0 2.6 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Laminin_II PF06009.7 KFP03555.1 - 1.7 8.3 8.5 0.76 9.5 2.3 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF310 PF03750.8 KFP03555.1 - 1.8 8.7 7.3 42 4.3 5.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF310) DUF2203 PF09969.4 KFP03555.1 - 2.3 8.4 9.7 2 8.6 0.4 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF848 PF05852.6 KFP03555.1 - 3.2 7.5 12.6 6.1 6.6 3.1 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Fib_alpha PF08702.5 KFP03555.1 - 3.3 7.8 10.8 1.7 8.7 3.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cytochrom_B562 PF07361.6 KFP03555.1 - 3.4 8.1 9.7 4.5 7.7 4.3 2.2 1 1 1 2 2 2 0 Cytochrome b562 DUF1978 PF09321.5 KFP03555.1 - 3.6 6.9 12.9 1.4 8.3 3.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) Spectrin PF00435.16 KFP03555.1 - 5.8 7.2 12.7 14 6.0 0.4 2.9 2 1 1 3 3 2 0 Spectrin repeat CENP-Q PF13094.1 KFP03555.1 - 6.9 6.6 16.5 1.7e+02 2.1 11.5 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin_2 PF14523.1 KFP03555.1 - 8.2 6.5 11.8 88 3.2 6.8 2.5 1 1 1 2 2 2 0 Syntaxin-like protein DUF342 PF03961.8 KFP03555.1 - 9.1 4.5 11.4 1 7.7 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Collagen PF01391.13 KFP03556.1 - 5.1e-164 531.9 679.8 1e-09 37.7 16.5 22.1 4 2 13 17 17 17 13 Collagen triple helix repeat (20 copies) COLFI PF01410.13 KFP03556.1 - 3.1e-85 284.9 0.1 4.8e-85 284.3 0.1 1.3 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Laminin_G_2 PF02210.19 KFP03556.1 - 1.4e-11 44.5 0.0 2.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFP03556.1 - 1.8e-05 25.0 0.0 3.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1735 PF08522.5 KFP03556.1 - 0.035 14.4 0.8 0.068 13.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Laminin_G_1 PF00054.18 KFP03556.1 - 0.039 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Hormone_recep PF00104.25 KFP03557.1 - 4.1e-42 143.6 0.0 5.8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 PF11825.3 KFP03557.1 - 1.6e-36 124.5 26.1 2.7e-36 123.8 18.1 1.4 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 zf-C4 PF00105.13 KFP03557.1 - 3.7e-32 110.3 16.2 6.2e-32 109.6 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Yae1_N PF09811.4 KFP03558.1 - 1.6e-12 46.6 38.3 0.0069 15.8 2.7 3.9 1 1 1 2 2 2 2 Essential protein Yae1, N terminal WD40 PF00400.27 KFP03559.1 - 1.1e-77 253.4 21.1 9.9e-13 47.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFP03559.1 - 2.1e-13 49.3 6.8 0.00058 18.1 0.5 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 KFP03559.1 - 4e-12 46.2 1.1 8.1e-06 25.6 0.0 3.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 KFP03559.1 - 0.00078 18.7 1.8 9.5 5.3 0.0 4.4 2 1 2 5 5 5 2 TUP1-like enhancer of split Nucleoporin_N PF08801.6 KFP03559.1 - 0.0029 16.4 8.1 0.049 12.3 1.1 4.2 1 1 1 3 3 3 1 Nup133 N terminal like DUF3312 PF11768.3 KFP03559.1 - 0.007 14.6 0.0 0.099 10.8 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3312) CDtoxinA PF03498.9 KFP03559.1 - 0.032 13.5 1.2 0.21 10.9 0.1 2.5 1 1 0 2 2 2 0 Cytolethal distending toxin A/C family VID27 PF08553.5 KFP03559.1 - 0.074 11.2 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Bromodomain PF00439.20 KFP03560.1 - 7.5e-46 153.9 5.7 2.5e-24 84.9 0.3 2.5 2 0 0 2 2 2 2 Bromodomain Gon7 PF08738.5 KFP03560.1 - 0.0022 17.9 5.9 0.0022 17.9 4.1 3.4 4 1 1 5 5 5 1 Gon7 family Pol_alpha_B_N PF08418.5 KFP03560.1 - 0.0042 16.6 14.3 0.0042 16.6 9.9 4.1 3 2 2 5 5 5 1 DNA polymerase alpha subunit B N-terminal MerR-DNA-bind PF09278.6 KFP03560.1 - 1.9 8.9 5.2 32 5.0 0.1 2.6 2 0 0 2 2 2 0 MerR, DNA binding RhoGEF PF00621.15 KFP03561.1 - 1.3e-39 135.9 7.9 1.3e-39 135.9 5.5 2.1 2 0 0 2 2 2 1 RhoGEF domain SH3_2 PF07653.12 KFP03561.1 - 8.5e-29 98.8 0.7 2.4e-14 52.5 0.1 3.7 3 0 0 3 3 3 2 Variant SH3 domain CAMSAP_CH PF11971.3 KFP03561.1 - 9.5e-23 79.6 0.6 3.4e-22 77.8 0.1 2.4 2 0 0 2 2 2 1 CAMSAP CH domain SH3_1 PF00018.23 KFP03561.1 - 1.1e-21 75.9 0.6 2.2e-12 46.1 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFP03561.1 - 9.9e-21 73.0 1.6 2.2e-11 43.1 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH2 PF00017.19 KFP03561.1 - 1.8e-15 56.4 0.1 6.1e-15 54.7 0.1 2.0 1 0 0 1 1 1 1 SH2 domain CH PF00307.26 KFP03561.1 - 1.5e-14 53.9 0.3 1.5e-13 50.6 0.0 2.8 2 0 0 2 2 2 1 Calponin homology (CH) domain C1_1 PF00130.17 KFP03561.1 - 5.2e-10 38.9 2.8 1.3e-09 37.6 1.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFP03561.1 - 2.6e-07 30.8 0.7 2.6e-07 30.8 0.5 2.1 2 0 0 2 2 1 1 PH domain SH3_3 PF08239.6 KFP03561.1 - 0.0001 22.4 0.8 0.085 13.0 0.3 3.2 3 0 0 3 3 3 1 Bacterial SH3 domain CDC24 PF06395.6 KFP03561.1 - 0.0092 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.1 KFP03561.1 - 0.0098 16.0 2.6 0.19 11.9 1.8 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain CotJB PF12652.2 KFP03561.1 - 0.084 12.9 2.6 2.4 8.2 0.0 2.8 2 0 0 2 2 2 0 CotJB protein Prok-RING_1 PF14446.1 KFP03561.1 - 0.58 9.9 7.3 0.05 13.3 1.4 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 1 DAO PF01266.19 KFP03562.1 - 1.8e-75 254.0 1.0 2.4e-75 253.7 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KFP03562.1 - 6.8e-53 179.1 0.0 1.1e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFP03562.1 - 1.3e-10 41.1 0.0 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 KFP03562.1 - 0.00028 20.7 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family ThiF PF00899.16 KFP03562.1 - 0.0015 18.3 0.3 0.0032 17.2 0.2 1.5 1 0 0 1 1 1 1 ThiF family Pyr_redox_3 PF13738.1 KFP03562.1 - 0.0017 18.4 0.0 0.097 12.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFP03562.1 - 0.0029 17.7 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KFP03562.1 - 0.003 16.4 0.2 0.0062 15.4 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFP03562.1 - 0.0071 16.7 0.0 0.027 14.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFP03562.1 - 0.009 15.1 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KFP03562.1 - 0.014 14.5 0.3 0.04 12.9 0.2 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 KFP03562.1 - 0.034 13.6 0.1 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KFP03562.1 - 0.05 12.6 1.8 0.094 11.7 0.2 1.9 2 0 0 2 2 2 0 FAD binding domain ETF PF01012.16 KFP03562.1 - 0.06 13.0 0.2 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Electron transfer flavoprotein domain GIDA PF01134.17 KFP03562.1 - 0.088 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 KFP03562.1 - 0.42 10.4 2.2 0.52 10.2 0.2 2.1 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 KFP03562.1 - 2.9 7.5 5.3 0.39 10.3 0.2 2.1 3 0 0 3 3 3 0 KR domain ADAM_spacer1 PF05986.9 KFP03563.1 - 1.7e-26 92.3 0.1 2.7e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFP03563.1 - 1.3e-21 76.4 108.6 3.2e-06 27.1 3.4 9.2 8 2 0 8 8 8 7 Thrombospondin type 1 domain PLAC PF08686.6 KFP03563.1 - 2.6e-12 46.7 9.5 1.4e-11 44.4 6.6 2.5 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain MipA PF06629.7 KFP03563.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 MltA-interacting protein MipA DUF3522 PF12036.3 KFP03564.1 - 1e-59 201.4 6.4 1.2e-59 201.2 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Oxidored_q5_N PF01059.12 KFP03564.1 - 0.063 13.1 6.3 0.042 13.7 2.2 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Sugar_tr PF00083.19 KFP03565.1 - 3e-85 286.4 17.7 3.6e-85 286.2 12.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP03565.1 - 1.5e-25 89.7 32.4 2.3e-25 89.0 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2474 PF10617.4 KFP03565.1 - 0.05 13.2 4.2 0.08 12.5 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) Cg6151-P PF10233.4 KFP03566.1 - 2.6e-34 117.5 4.8 3.2e-34 117.3 3.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4191 PF13829.1 KFP03566.1 - 0.014 14.4 0.1 0.014 14.4 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) RebB PF11747.3 KFP03566.1 - 0.097 12.5 1.0 0.19 11.6 0.2 1.8 2 0 0 2 2 2 0 Killing trait MRAP PF15183.1 KFP03566.1 - 3.4 7.3 4.9 13 5.4 0.7 2.2 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family CUB PF00431.15 KFP03567.1 - 0.00011 22.1 0.1 0.00087 19.3 0.0 2.0 2 0 0 2 2 2 1 CUB domain Reprolysin_3 PF13582.1 KFP03568.1 - 8.8e-06 26.2 0.0 9.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 KFP03568.1 - 0.0035 16.9 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.1 KFP03568.1 - 0.013 15.5 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP03568.1 - 0.031 13.7 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like RNase_T PF00929.19 KFP03569.1 - 7.8e-27 94.5 0.0 1.5e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KFP03569.1 - 5.3e-05 22.7 0.0 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Sec62 PF03839.11 KFP03569.1 - 1.4 8.2 9.1 4.2 6.7 6.3 1.8 1 0 0 1 1 1 0 Translocation protein Sec62 RICTOR_M PF14666.1 KFP03570.1 - 0.077 11.9 0.4 1.2 8.0 0.0 2.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Arm PF00514.18 KFP03570.1 - 4.5 7.2 9.0 3.7 7.5 0.1 4.3 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 KFP03571.1 - 1.4e-35 122.7 0.5 1.5e-35 122.5 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03571.1 - 9.7e-27 93.6 1.7 1.1e-26 93.5 1.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP03571.1 - 2.8e-07 29.8 0.0 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP03571.1 - 0.0017 17.4 0.1 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SURF4 PF02077.10 KFP03572.1 - 1.1e-122 408.6 9.5 1.2e-122 408.4 6.6 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KFP03572.1 - 0.061 13.7 0.2 0.061 13.7 0.1 3.4 4 1 1 5 5 5 0 DoxX SURF2 PF05477.6 KFP03573.1 - 3.8e-93 311.1 3.1 4.5e-93 310.8 2.1 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) SURF1 PF02104.10 KFP03574.1 - 2.6e-56 190.7 0.0 3.2e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Ribosomal_L7Ae PF01248.21 KFP03575.1 - 7e-10 38.2 0.0 1.6e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Med22 PF06179.7 KFP03576.1 - 1.4e-34 118.4 4.9 1.7e-34 118.0 3.4 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex UPRTase PF14681.1 KFP03576.1 - 0.034 13.3 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase SURF6 PF04935.7 KFP03577.1 - 1.1e-45 155.4 68.3 1.1e-45 155.5 47.3 2.2 1 1 1 2 2 2 1 Surfeit locus protein 6 DUF4455 PF14643.1 KFP03578.1 - 1.1e-37 129.8 9.7 1.2e-37 129.6 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) Mannosyl_trans2 PF04188.8 KFP03578.1 - 0.0084 15.0 0.2 0.0089 14.9 0.1 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF4456 PF14644.1 KFP03580.1 - 2.9e-44 150.7 7.6 3.2e-44 150.6 5.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) tRNA_bind_2 PF13725.1 KFP03580.1 - 0.036 14.1 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 Possible tRNA binding domain DUF842 PF05811.8 KFP03580.1 - 0.59 9.5 5.4 0.42 10.0 0.8 2.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Glyco_transf_6 PF03414.8 KFP03581.1 - 1.4e-143 477.4 0.0 1.7e-143 477.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 6 Glyco_tranf_2_4 PF13704.1 KFP03581.1 - 0.0064 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Tau95 PF09734.4 KFP03582.1 - 2.2e-66 224.3 0.1 3.9e-66 223.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit COesterase PF00135.23 KFP03583.1 - 8.7e-152 506.5 0.0 9.8e-152 506.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFP03583.1 - 1.7e-07 31.0 0.0 3.9e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFP03583.1 - 0.0006 19.0 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family zf-H2C2_2 PF13465.1 KFP03584.1 - 1.3e-32 110.5 44.4 7.1e-08 32.3 1.3 7.3 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03584.1 - 7.7e-29 98.2 45.7 1.2e-05 25.3 1.0 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03584.1 - 1.9e-22 77.8 38.2 0.0012 19.0 0.2 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP03584.1 - 1.6e-16 59.9 27.3 0.0073 16.4 0.0 6.9 7 0 0 7 7 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP03584.1 - 6.8e-09 35.6 37.1 0.0062 16.6 0.3 7.0 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP03584.1 - 7e-08 32.1 33.2 0.00019 21.1 1.0 6.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-CHCC PF10276.4 KFP03584.1 - 0.00018 21.3 9.1 0.077 12.8 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger domain C1_1 PF00130.17 KFP03584.1 - 0.00024 20.7 21.9 0.16 11.7 2.8 3.8 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Ta0938 PF11494.3 KFP03584.1 - 0.0021 18.1 0.3 0.68 10.0 0.0 2.5 2 0 0 2 2 2 1 Ta0938 Prok-RING_1 PF14446.1 KFP03584.1 - 0.0025 17.4 14.7 6.6 6.5 0.0 6.0 6 0 0 6 6 6 1 Prokaryotic RING finger family 1 zf-BED PF02892.10 KFP03584.1 - 0.006 16.3 33.8 0.0082 15.8 1.3 5.7 4 2 2 6 6 6 2 BED zinc finger Rpr2 PF04032.11 KFP03584.1 - 0.0064 16.3 11.6 0.061 13.2 0.1 3.4 3 0 0 3 3 3 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.5 KFP03584.1 - 0.0067 16.3 25.2 2.9 7.9 0.1 5.9 4 2 1 5 5 5 1 Zinc ribbon domain FYVE PF01363.16 KFP03584.1 - 0.08 12.8 28.5 2.4 8.1 5.7 3.9 1 1 3 4 4 4 0 FYVE zinc finger zf-CHY PF05495.7 KFP03584.1 - 0.13 12.4 22.8 2.5 8.3 7.7 3.6 1 1 2 3 3 3 0 CHY zinc finger GAGA PF09237.6 KFP03584.1 - 0.14 11.7 7.7 5.7 6.6 0.1 3.9 2 2 2 4 4 4 0 GAGA factor BolA PF01722.13 KFP03584.1 - 0.48 10.4 6.9 18 5.3 0.2 3.6 2 2 1 3 3 3 0 BolA-like protein zf-C2H2_2 PF12756.2 KFP03584.1 - 1.1 9.4 31.0 2 8.5 0.3 6.4 2 1 4 6 6 6 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.8 KFP03584.1 - 1.2 8.8 21.3 0.23 11.1 0.9 3.9 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like PyrI_C PF02748.10 KFP03584.1 - 1.6 8.2 15.4 2.4 7.6 0.1 5.1 3 1 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HypA PF01155.14 KFP03584.1 - 2.5 7.8 14.3 1.7 8.3 2.2 3.3 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family zf-Di19 PF05605.7 KFP03584.1 - 4.6 7.4 36.6 7.5 6.7 6.8 4.7 2 1 2 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding DUF4561 PF15120.1 KFP03585.1 - 3.5e-79 264.1 0.3 4.2e-79 263.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4561) ADK PF00406.17 KFP03586.1 - 1.6e-40 138.4 0.0 1.1e-22 80.4 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KFP03586.1 - 1.2e-18 68.0 0.0 6.1e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFP03586.1 - 6.4e-15 55.2 0.0 2e-09 37.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFP03586.1 - 7.7e-14 52.1 0.0 1.8e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KFP03586.1 - 2.4e-09 37.5 0.1 0.00038 20.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 KFP03586.1 - 7.5e-07 28.6 0.0 0.0075 15.5 0.0 2.5 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_22 PF13401.1 KFP03586.1 - 2.6e-06 27.6 0.0 0.079 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFP03586.1 - 1.3e-05 25.2 0.0 0.044 13.7 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 KFP03586.1 - 1.7e-05 24.4 0.0 0.093 12.4 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain RuvB_N PF05496.7 KFP03586.1 - 8.7e-05 21.6 0.0 0.27 10.2 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KFP03586.1 - 0.00052 19.4 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KFP03586.1 - 0.0006 19.8 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KFP03586.1 - 0.00068 19.1 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFP03586.1 - 0.00069 18.8 0.0 0.26 10.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KFP03586.1 - 0.00071 19.5 0.0 0.32 10.9 0.0 2.5 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 KFP03586.1 - 0.00083 19.5 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 KFP03586.1 - 0.00097 19.4 0.0 1.1 9.5 0.0 2.4 2 1 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.7 KFP03586.1 - 0.0011 18.1 0.0 1.4 7.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 KFP03586.1 - 0.0017 18.0 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KFP03586.1 - 0.0023 17.4 0.0 3 7.2 0.0 3.0 2 1 0 3 3 3 1 AAA-like domain Thymidylate_kin PF02223.12 KFP03586.1 - 0.006 15.9 0.0 2.8 7.2 0.0 3.0 3 0 0 3 3 3 1 Thymidylate kinase ResIII PF04851.10 KFP03586.1 - 0.0066 16.2 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 KFP03586.1 - 0.011 15.4 0.0 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain SKI PF01202.17 KFP03586.1 - 0.013 15.3 0.6 0.33 10.7 0.0 2.7 2 2 0 2 2 2 0 Shikimate kinase AAA_11 PF13086.1 KFP03586.1 - 0.025 14.1 0.1 0.26 10.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFP03586.1 - 0.047 13.2 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 KFP03586.1 - 0.054 13.2 0.0 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KFP03586.1 - 0.07 13.0 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFP03586.1 - 0.082 12.3 0.0 13 5.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family PMBR PF09373.5 KFP03586.1 - 0.082 12.8 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat NB-ARC PF00931.17 KFP03586.1 - 0.085 11.6 0.0 0.76 8.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.21 KFP03586.1 - 0.11 11.9 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ADK_lid PF05191.9 KFP03587.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase, active site lid ADK PF00406.17 KFP03587.1 - 0.043 13.6 0.1 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Adenylate kinase DUF3973 PF13119.1 KFP03587.1 - 0.047 13.6 0.1 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) SYS1 PF09801.4 KFP03588.1 - 4.9e-07 29.8 18.2 6.8e-07 29.3 12.6 1.2 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Laminin_G_1 PF00054.18 KFP03589.1 - 3.1e-08 33.6 0.0 4.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 KFP03589.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_I PF06008.9 KFP03590.1 - 1.4e-50 172.1 15.0 1.5e-50 171.9 10.4 1.0 1 0 0 1 1 1 1 Laminin Domain I ADIP PF11559.3 KFP03590.1 - 0.001 18.9 10.5 0.001 18.9 7.3 2.1 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DUF3484 PF11983.3 KFP03590.1 - 0.1 13.4 2.7 0.71 10.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) DUF3053 PF11254.3 KFP03590.1 - 0.2 10.8 5.1 0.17 11.1 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) DUF883 PF05957.8 KFP03590.1 - 0.26 11.7 18.1 0.57 10.6 1.0 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) EntA_Immun PF08951.5 KFP03590.1 - 0.33 11.1 3.8 0.43 10.7 0.8 2.4 2 1 0 2 2 2 0 Enterocin A Immunity Laminin_II PF06009.7 KFP03590.1 - 0.49 10.1 13.5 5.7 6.7 1.7 3.2 1 1 2 3 3 3 0 Laminin Domain II TIP120 PF08623.5 KFP03590.1 - 0.53 9.8 5.2 0.16 11.5 0.8 2.0 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) Lipoprotein_6 PF01441.14 KFP03590.1 - 0.65 9.8 7.8 2 8.2 4.9 2.0 1 1 1 2 2 2 0 Lipoprotein zf-ZPR1 PF03367.8 KFP03590.1 - 0.77 8.9 4.9 4.7 6.3 0.2 2.2 1 1 0 2 2 2 0 ZPR1 zinc-finger domain DUF948 PF06103.6 KFP03590.1 - 0.93 9.3 8.5 4.1 7.3 1.2 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF334 PF03904.8 KFP03590.1 - 1.1 8.5 6.8 1.5 8.1 4.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Astro_capsid PF03115.9 KFP03590.1 - 1.3 7.1 6.0 1.6 6.9 4.1 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Prominin PF05478.6 KFP03590.1 - 1.4 6.3 6.2 2 5.8 4.3 1.2 1 0 0 1 1 1 0 Prominin HisKA_3 PF07730.8 KFP03590.1 - 1.6 9.0 15.2 6.5 7.1 0.5 4.4 1 1 2 3 3 3 0 Histidine kinase Ferritin PF00210.19 KFP03590.1 - 2 8.1 9.6 0.58 9.9 1.2 2.2 1 1 1 2 2 2 0 Ferritin-like domain OmpH PF03938.9 KFP03590.1 - 2.5 8.0 17.3 0.16 11.8 5.0 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Acyl-CoA_dh_C PF12806.2 KFP03590.1 - 2.5 7.9 7.2 3.3 7.5 1.1 2.8 1 1 2 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Toxin_52 PF15605.1 KFP03590.1 - 3.1 7.7 10.5 8.3 6.3 0.1 3.5 2 1 1 3 3 3 0 Putative toxin 52 YlqD PF11068.3 KFP03590.1 - 5.2 7.1 13.9 0.79 9.7 2.5 2.9 1 1 2 3 3 3 0 YlqD protein TPR_MLP1_2 PF07926.7 KFP03590.1 - 5.8 6.6 15.5 1e+02 2.6 9.9 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 KFP03590.1 - 8.8 6.3 18.2 12 5.9 6.9 3.0 1 1 1 3 3 3 0 DivIVA protein DUF3391 PF11871.3 KFP03590.1 - 9.5 6.4 11.0 2e+03 -1.1 7.6 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Laminin_N PF00055.12 KFP03591.1 - 5.2e-89 297.3 0.1 5.2e-89 297.3 0.0 1.8 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFP03591.1 - 1.7e-50 168.7 145.9 8.6e-10 38.3 7.2 8.9 9 0 0 9 9 9 8 Laminin EGF-like (Domains III and V) Laminin_B PF00052.13 KFP03591.1 - 2e-28 98.7 0.0 2.8e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) Aa_trans PF01490.13 KFP03592.1 - 8.3e-70 235.3 29.6 9.5e-70 235.1 20.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Y_phosphatase PF00102.22 KFP03593.1 - 4.9e-156 516.9 0.1 5.3e-89 297.5 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFP03593.1 - 1.6e-24 85.8 0.3 5.7e-10 39.1 0.0 5.1 5 0 0 5 5 5 2 Fibronectin type III domain MAM PF00629.18 KFP03593.1 - 7.9e-23 80.9 0.0 1.6e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 MAM domain DSPc PF00782.15 KFP03593.1 - 1.8e-08 34.0 1.2 0.002 17.7 0.1 2.6 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Ig_2 PF13895.1 KFP03593.1 - 1.6e-07 31.3 0.0 4.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP03593.1 - 4.2e-07 29.7 0.0 1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain Y_phosphatase3 PF13350.1 KFP03593.1 - 1.3e-05 25.5 0.0 0.07 13.3 0.0 2.8 3 0 0 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP03593.1 - 0.0014 18.7 0.2 0.15 12.1 0.0 2.9 3 0 0 3 3 3 1 Inositol hexakisphosphate Ly49 PF08391.5 KFP03593.1 - 0.0045 17.1 0.1 0.32 11.1 0.1 2.5 2 0 0 2 2 2 1 Ly49-like protein, N-terminal region EphA2_TM PF14575.1 KFP03593.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain V-set PF07686.12 KFP03593.1 - 0.026 14.4 0.1 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 Immunoglobulin V-set domain Lep_receptor_Ig PF06328.6 KFP03593.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Ig-like C2-type domain Protocadherin PF08374.6 KFP03593.1 - 0.33 10.5 1.9 0.33 10.5 0.2 1.7 2 0 0 2 2 2 0 Protocadherin CABIT PF12736.2 KFP03594.1 - 4.8e-79 264.9 6.1 1.2e-44 152.2 1.0 2.1 2 0 0 2 2 2 2 Cell-cycle sustaining, positive selection, DUF1966 PF09260.6 KFP03594.1 - 0.055 13.5 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) DUF781 PF05612.7 KFP03595.1 - 3.7e-114 381.1 0.1 5.4e-114 380.6 0.1 1.2 1 0 0 1 1 1 1 Mouse protein of unknown function (DUF781) DUF3166 PF11365.3 KFP03596.1 - 2.6e-68 226.5 38.0 3.1e-43 146.1 1.1 4.9 4 1 0 5 5 5 2 Protein of unknown function (DUF3166) DUF2968 PF11180.3 KFP03596.1 - 0.00017 21.0 7.2 0.00017 21.0 5.0 3.7 3 1 1 5 5 5 1 Protein of unknown function (DUF2968) TSC22 PF01166.13 KFP03596.1 - 0.0038 17.1 0.3 0.0038 17.1 0.2 7.0 7 1 0 7 7 7 3 TSC-22/dip/bun family Halo_GVPC PF05465.8 KFP03596.1 - 0.047 13.6 0.5 0.14 12.1 0.4 1.8 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF2207 PF09972.4 KFP03596.1 - 0.057 12.0 0.1 0.057 12.0 0.1 2.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) TPR_MLP1_2 PF07926.7 KFP03596.1 - 0.092 12.4 40.8 0.17 11.6 5.1 5.1 3 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein Fes1 PF08609.5 KFP03596.1 - 0.63 10.5 7.7 2.1 8.8 4.0 2.9 2 1 1 3 3 3 0 Nucleotide exchange factor Fes1 APG6 PF04111.7 KFP03596.1 - 1.4 7.8 48.9 0.53 9.2 0.0 4.2 1 1 2 4 4 4 0 Autophagy protein Apg6 DUF972 PF06156.8 KFP03596.1 - 8.4 6.7 48.4 1.1 9.6 5.7 6.6 3 2 3 7 7 7 0 Protein of unknown function (DUF972) DUF4482 PF14818.1 KFP03597.1 - 3.4e-33 115.2 16.8 3.4e-33 115.2 11.6 3.9 3 1 2 5 5 5 1 Domain of unknown function (DUF4482) WWE PF02825.15 KFP03598.1 - 1.8e-13 49.7 0.9 3.6e-13 48.7 0.6 1.5 1 0 0 1 1 1 1 WWE domain zf-RING_2 PF13639.1 KFP03598.1 - 2.8e-06 27.0 11.8 5.7e-06 26.0 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFP03598.1 - 6.3e-06 25.7 10.2 1.1e-05 24.9 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP03598.1 - 1.5e-05 24.5 9.4 3.6e-05 23.3 6.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP03598.1 - 5.3e-05 23.1 13.2 9.4e-05 22.3 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP03598.1 - 0.0068 16.1 11.4 0.012 15.2 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP03598.1 - 0.013 15.3 10.7 0.013 15.3 7.4 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFP03598.1 - 0.076 12.7 9.0 0.17 11.6 6.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger MgsA_C PF12002.3 KFP03598.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal zf-RING_6 PF14835.1 KFP03598.1 - 1 9.1 7.0 2.1 8.2 4.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Yae1_N PF09811.4 KFP03599.1 - 1.6e-19 69.1 57.7 0.0018 17.7 5.3 5.2 1 1 1 2 2 2 1 Essential protein Yae1, N terminal CENP-W PF15510.1 KFP03601.1 - 2.2e-17 62.8 0.5 2.4e-17 62.8 0.4 1.0 1 0 0 1 1 1 1 Centromere kinetochore component W CBFD_NFYB_HMF PF00808.18 KFP03601.1 - 0.0031 17.5 0.3 0.0036 17.3 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UPF0020 PF01170.13 KFP03602.1 - 5.3e-14 52.1 0.0 1.4e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KFP03602.1 - 9.7e-08 32.0 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KFP03602.1 - 3e-05 23.2 0.0 4.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 KFP03602.1 - 0.0046 16.4 0.1 0.42 10.0 0.0 2.4 2 0 0 2 2 2 1 DNA methylase Eco57I PF07669.6 KFP03602.1 - 0.056 13.7 0.1 0.27 11.5 0.0 2.2 3 0 0 3 3 3 0 Eco57I restriction-modification methylase Methyltransf_15 PF09445.5 KFP03602.1 - 0.089 12.3 0.1 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Costars PF14705.1 KFP03603.1 - 9.8e-34 115.1 0.1 1.2e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 Costars DcpS_C PF11969.3 KFP03604.1 - 1.8e-30 105.5 0.0 2.1e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KFP03604.1 - 2.6e-08 34.3 1.3 4.3e-08 33.5 0.9 1.4 1 1 0 1 1 1 1 HIT domain TLD PF07534.11 KFP03605.1 - 5.3e-40 136.6 0.5 6e-40 136.4 0.4 1.0 1 0 0 1 1 1 1 TLD HLH PF00010.21 KFP03606.1 - 4.1e-18 64.8 2.7 6.6e-18 64.1 1.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFP03606.1 - 3.1e-14 52.4 0.1 5.7e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Hairy Orange DUF3772 PF12607.3 KFP03606.1 - 0.69 9.5 6.4 0.57 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) HD_3 PF13023.1 KFP03607.1 - 1.3e-46 158.3 1.0 1.6e-46 158.1 0.7 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 KFP03607.1 - 8.7e-05 22.5 0.4 0.00016 21.6 0.3 1.4 1 0 0 1 1 1 1 HD domain DUF4259 PF14078.1 KFP03607.1 - 0.016 15.7 0.2 0.024 15.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) HDOD PF08668.7 KFP03607.1 - 0.074 12.3 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 HDOD domain TPD52 PF04201.10 KFP03608.1 - 6.4e-61 204.8 3.8 9.1e-61 204.2 2.6 1.2 1 0 0 1 1 1 1 Tumour protein D52 family DUF2656 PF10847.3 KFP03608.1 - 0.053 13.4 0.3 0.082 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) Rifin_STEVOR PF02009.11 KFP03608.1 - 0.12 11.9 1.3 0.2 11.2 0.8 1.3 2 0 0 2 2 2 0 Rifin/stevor family IBR PF01485.16 KFP03609.1 - 1.3e-17 63.3 28.4 2.8e-09 36.6 5.1 2.9 3 0 0 3 3 3 2 IBR domain C1_4 PF07975.7 KFP03609.1 - 3.6 7.6 26.3 0.18 11.8 1.1 4.1 3 1 0 3 3 3 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.7 KFP03609.1 - 3.6 7.4 28.5 0.051 13.3 4.8 3.9 3 1 1 4 4 4 0 zinc-ribbons NKAIN PF05640.9 KFP03610.1 - 4.9e-90 299.8 5.3 5.4e-90 299.7 3.6 1.0 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein Asp-B-Hydro_N PF05279.6 KFP03611.1 - 2e-07 31.1 1.7 2e-07 31.1 1.2 2.1 2 0 0 2 2 2 1 Aspartyl beta-hydroxylase N-terminal region PLRV_ORF5 PF01690.12 KFP03611.1 - 0.03 13.4 19.6 0.042 13.0 13.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF572 PF04502.8 KFP03611.1 - 2.7 7.1 27.9 3.8 6.6 19.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FGF-BP1 PF06473.7 KFP03611.1 - 8 5.9 25.6 0.47 10.0 8.9 2.1 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) DUF2201_N PF13203.1 KFP03611.1 - 8.4 5.4 12.8 13 4.8 8.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 KFP03611.1 - 9.9 4.0 15.8 14 3.5 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein CRAL_TRIO PF00650.15 KFP03612.1 - 1.1e-34 119.2 0.0 1.7e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFP03612.1 - 8.3e-09 35.5 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFP03612.1 - 4.4e-07 29.9 0.2 1.2e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Metallophos PF00149.23 KFP03613.1 - 5.7e-18 65.0 0.1 8.6e-18 64.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipocalin PF00061.18 KFP03614.1 - 5e-29 101.1 2.2 5.6e-29 100.9 1.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFP03614.1 - 6.2e-07 29.1 1.1 8e-07 28.8 0.8 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DBP10CT PF08147.7 KFP03614.1 - 0.13 12.1 0.3 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 DBP10CT (NUC160) domain PKI PF02827.11 KFP03615.1 - 2.7e-23 81.8 0.0 2.9e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Serinc PF03348.10 KFP03616.1 - 4e-181 602.4 13.1 4.5e-181 602.2 9.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2391 PF09622.5 KFP03616.1 - 0.39 9.8 4.6 0.053 12.6 0.4 1.6 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) Vert_HS_TF PF06546.6 KFP03617.1 - 6.1e-73 245.4 24.5 1.1e-66 224.9 9.9 2.3 1 1 1 2 2 2 2 Vertebrate heat shock transcription factor HSF_DNA-bind PF00447.12 KFP03617.1 - 6.2e-27 93.7 0.7 1.3e-26 92.7 0.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding bZIP_2 PF07716.10 KFP03617.1 - 0.011 15.5 1.4 0.029 14.2 1.0 1.7 1 0 0 1 1 1 0 Basic region leucine zipper APG6 PF04111.7 KFP03617.1 - 0.091 11.7 4.6 0.15 11.0 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Connexin PF00029.14 KFP03619.1 - 2.7e-50 168.9 0.1 6.5e-50 167.6 0.1 1.6 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFP03619.1 - 1.3e-31 108.1 2.9 3.3e-31 106.9 2.0 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Connexin43 PF03508.8 KFP03619.1 - 8.8e-12 44.0 15.8 1.8e-11 42.9 11.0 1.6 1 0 0 1 1 1 1 Gap junction alpha-1 protein (Cx43) TMEM154 PF15102.1 KFP03619.1 - 0.043 13.5 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family BROMI PF14961.1 KFP03621.1 - 0 1906.6 24.3 0 1904.4 16.8 1.7 1 1 0 1 1 1 1 Broad-minded protein RabGAP-TBC PF00566.13 KFP03621.1 - 0.0036 16.7 5.5 0.0036 16.7 3.8 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Glyco_hydro_47 PF01532.15 KFP03622.1 - 4.5e-153 510.1 0.0 5.1e-153 509.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 KFP03622.1 - 0.022 13.8 0.1 0.099 11.6 0.1 2.0 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 MCM PF00493.18 KFP03623.1 - 3.1e-106 354.9 0.0 4.7e-106 354.3 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KFP03623.1 - 6.7e-09 35.2 0.1 0.00034 19.8 0.0 2.7 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFP03623.1 - 1.7e-07 31.0 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.1 KFP03623.1 - 0.0027 18.1 0.0 0.0067 16.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.6 KFP03623.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP03623.1 - 0.079 13.0 0.4 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFP03623.1 - 0.08 12.4 0.0 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Rota_NS6 PF04866.7 KFP03623.1 - 1.9 8.5 7.1 4.5 7.3 0.1 3.3 2 1 1 3 3 3 0 Rotavirus non-structural protein 6 ASF1_hist_chap PF04729.8 KFP03624.1 - 1.3e-69 232.7 0.2 1.6e-69 232.4 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0154 PF03672.8 KFP03624.1 - 0.051 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Phospholamban PF04272.9 KFP03625.1 - 2.4e-36 122.9 8.8 2.6e-36 122.8 6.1 1.0 1 0 0 1 1 1 1 Phospholamban Sarcolipin PF05366.6 KFP03625.1 - 0.0072 15.7 5.9 0.013 14.8 4.1 1.5 1 1 0 1 1 1 1 Sarcolipin DUF1705 PF08019.7 KFP03625.1 - 0.029 13.8 0.4 0.03 13.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) DUF914 PF06027.7 KFP03626.1 - 4.3e-133 443.3 11.3 4.9e-133 443.1 7.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFP03626.1 - 7.6e-13 48.5 23.7 3.3e-07 30.3 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KFP03626.1 - 0.00026 20.6 19.3 0.019 14.6 6.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Mg_trans_NIPA PF05653.9 KFP03626.1 - 0.0015 17.5 2.5 0.0015 17.5 1.7 2.0 1 1 0 2 2 2 1 Magnesium transporter NIPA UAA PF08449.6 KFP03626.1 - 0.0049 15.8 14.7 0.0076 15.1 10.2 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KFP03626.1 - 0.025 14.7 6.5 0.025 14.7 4.5 2.6 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF809 PF05663.6 KFP03626.1 - 0.098 12.5 0.1 0.098 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Prenyltransf PF01255.14 KFP03627.1 - 3.1e-08 33.0 0.0 3.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3369 PF11849.3 KFP03627.1 - 0.015 15.2 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) LRR_8 PF13855.1 KFP03628.1 - 1e-49 166.0 53.6 5.9e-12 45.1 1.0 7.3 3 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 KFP03628.1 - 2.4e-35 119.5 54.2 9.9e-08 31.4 0.7 10.4 4 4 8 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP03628.1 - 9.9e-23 76.6 45.3 0.024 14.6 0.1 15.6 15 2 1 16 16 16 7 Leucine Rich Repeat LRR_7 PF13504.1 KFP03628.1 - 6e-12 43.7 47.1 0.17 12.2 0.2 15.6 17 0 0 17 17 17 4 Leucine rich repeat LRR_5 PF13306.1 KFP03628.1 - 1.4e-10 40.9 1.2 1.5e-05 24.7 0.2 3.5 3 1 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFP03628.1 - 4.3e-05 23.1 52.9 1.6 9.0 0.2 13.9 11 4 3 14 14 14 3 Leucine Rich repeat LRR_9 PF14580.1 KFP03628.1 - 0.013 15.0 19.5 0.4 10.2 0.6 5.2 1 1 1 5 5 5 0 Leucine-rich repeat FNIP PF05725.7 KFP03628.1 - 0.48 10.4 0.0 0.48 10.4 0.0 4.3 3 2 0 3 3 3 0 FNIP Repeat PDZ PF00595.19 KFP03630.1 - 9.2e-17 60.9 2.1 9.7e-17 60.9 0.4 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP03630.1 - 2.8e-05 23.9 0.4 0.00021 21.1 0.0 2.4 2 1 0 2 2 2 1 PDZ domain bZIP_2 PF07716.10 KFP03630.1 - 0.0083 15.9 7.6 0.0083 15.9 5.3 2.8 2 0 0 2 2 2 1 Basic region leucine zipper DUF903 PF06004.7 KFP03630.1 - 0.066 12.7 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) DUF4254 PF14063.1 KFP03630.1 - 0.48 10.0 6.0 1.2 8.7 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DivIC PF04977.10 KFP03630.1 - 0.81 9.2 12.3 0.99 8.9 1.7 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 KFP03630.1 - 0.89 10.0 10.3 0.19 12.1 1.1 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 KFP03630.1 - 1.3 7.9 12.4 3.1 6.6 8.6 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 F5_F8_type_C PF00754.20 KFP03631.1 - 5.7e-27 94.0 3.0 5.7e-27 94.0 2.1 2.1 3 0 0 3 3 3 1 F5/8 type C domain CUB PF00431.15 KFP03631.1 - 9.6e-19 67.4 0.4 2.7e-18 66.0 0.0 2.0 3 0 0 3 3 3 1 CUB domain LCCL PF03815.14 KFP03631.1 - 1.1e-17 63.7 0.2 2.6e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 LCCL domain Pkinase_Tyr PF07714.12 KFP03632.1 - 3.3e-96 321.3 0.0 5.5e-96 320.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP03632.1 - 3e-45 154.3 0.0 4.9e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFP03632.1 - 1.3e-44 150.1 33.6 3.3e-08 33.5 0.0 10.0 9 0 0 9 9 9 9 Fibronectin type III domain Vg_Tdu PF07545.9 KFP03633.1 - 6.1e-21 73.5 0.2 1e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Vestigial/Tondu family FAM181 PF15238.1 KFP03633.1 - 0.47 10.4 9.3 0.82 9.6 6.5 1.5 1 1 0 1 1 1 0 FAM181 Innate_immun PF12782.2 KFP03633.1 - 6.5 5.8 13.3 9.7 5.3 9.2 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family RFX_DNA_binding PF02257.10 KFP03634.1 - 6.5e-31 106.3 0.2 2e-30 104.7 0.2 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFP03634.1 - 0.068 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like DUF1075 PF06388.6 KFP03635.1 - 4.3e-48 162.6 1.9 4.8e-48 162.5 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1075) Arm PF00514.18 KFP03636.1 - 1.4e-87 284.8 13.3 1.1e-12 47.2 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP03636.1 - 8.6e-30 102.8 0.0 2.8e-08 33.9 0.0 5.4 3 1 3 6 6 6 4 HEAT repeats IBB PF01749.15 KFP03636.1 - 2.7e-28 97.9 1.7 6.2e-28 96.8 1.2 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFP03636.1 - 3.6e-25 87.7 1.5 3.1e-07 30.6 0.0 6.0 5 1 1 6 6 6 5 HEAT-like repeat HEAT PF02985.17 KFP03636.1 - 2.7e-18 64.3 10.5 6.7e-05 22.6 0.0 8.9 9 1 0 9 9 8 4 HEAT repeat RICTOR_V PF14668.1 KFP03636.1 - 3.9e-06 26.7 0.6 1.3 9.0 0.0 5.1 4 3 2 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.8 KFP03636.1 - 1.3e-05 24.4 0.0 0.025 13.6 0.0 2.9 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_C PF11698.3 KFP03636.1 - 6.6e-05 22.8 0.0 0.35 10.7 0.0 4.3 3 2 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.15 KFP03636.1 - 0.00019 19.9 0.0 0.0024 16.2 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_PBS PF03130.11 KFP03636.1 - 0.0016 18.6 0.4 5.4 7.7 0.0 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 KFP03636.1 - 0.0078 14.5 0.0 1.5 7.0 0.0 2.8 1 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Peptidase_C78 PF07910.8 KFP03637.1 - 1.8e-72 242.9 0.0 3e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.14 KFP03637.1 - 0.025 13.7 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C54 zf-C2H2_4 PF13894.1 KFP03637.1 - 0.21 11.9 1.8 0.64 10.4 1.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Sulfotransfer_1 PF00685.22 KFP03638.1 - 1.1e-74 251.0 0.3 1.3e-74 250.8 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP03638.1 - 0.052 14.4 0.0 0.088 13.7 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase family RWD PF05773.17 KFP03639.1 - 3.3e-16 59.1 0.2 3.3e-16 59.1 0.1 1.6 2 0 0 2 2 2 1 RWD domain DUF445 PF04286.7 KFP03639.1 - 0.0019 17.8 4.8 0.0022 17.6 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF4484 PF14831.1 KFP03639.1 - 0.038 14.0 3.2 0.044 13.8 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) GOLD_2 PF13897.1 KFP03639.1 - 0.13 12.4 1.5 0.19 11.9 0.7 1.5 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking EAP30 PF04157.11 KFP03639.1 - 0.26 10.4 4.8 0.34 10.0 3.1 1.4 1 1 0 1 1 1 0 EAP30/Vps36 family Folliculin PF11704.3 KFP03639.1 - 0.31 10.5 4.4 0.55 9.7 3.0 1.5 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Hydrolase_3 PF08282.7 KFP03639.1 - 0.31 10.5 4.1 0.43 10.1 2.9 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase VTC PF09359.5 KFP03639.1 - 1.9 7.4 8.0 2.7 6.9 5.5 1.2 1 0 0 1 1 1 0 VTC domain UPF0542 PF15086.1 KFP03639.1 - 3.6 7.3 6.0 7.4 6.3 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Ca_hom_mod PF14798.1 KFP03640.1 - 1.4e-91 305.9 4.4 1.6e-91 305.7 3.0 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator TRAPP PF04051.11 KFP03641.1 - 4.4e-33 113.9 0.0 5.3e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ca_hom_mod PF14798.1 KFP03642.1 - 4.6e-89 297.7 12.9 5.5e-89 297.4 9.0 1.1 1 0 0 1 1 1 1 Calcium homeostasis modulator ACOX PF01756.14 KFP03642.1 - 0.082 12.2 0.6 0.18 11.1 0.4 1.5 1 0 0 1 1 1 0 Acyl-CoA oxidase DltD_M PF04918.7 KFP03643.1 - 0.032 14.4 2.6 0.073 13.2 1.8 1.5 1 0 0 1 1 1 0 DltD central region DUF1673 PF07895.6 KFP03643.1 - 0.41 10.1 6.7 2.5 7.5 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Glyco_hydro_38C PF07748.8 KFP03644.1 - 2.2e-86 290.5 2.2 2.2e-86 290.5 1.5 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.17 KFP03644.1 - 6e-73 245.4 3.2 6e-73 245.4 2.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 KFP03644.1 - 5.6e-16 58.5 0.1 1.4e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain S_100 PF01023.14 KFP03645.1 - 2.3e-18 65.2 0.1 1.3e-17 62.7 0.0 2.1 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 KFP03645.1 - 1.5e-07 31.4 0.3 1.8e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP03645.1 - 1.7e-07 30.5 0.9 0.00064 19.3 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFP03645.1 - 4.8e-05 22.3 1.1 4.8e-05 22.3 0.8 2.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 KFP03645.1 - 0.0025 17.4 1.2 0.0056 16.2 0.9 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP03645.1 - 0.021 14.1 4.2 0.17 11.3 1.4 2.5 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.4 KFP03645.1 - 0.042 13.8 0.6 0.084 12.9 0.4 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFP03645.1 - 0.069 12.8 0.1 0.082 12.6 0.1 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand YxiJ PF14176.1 KFP03645.1 - 0.075 13.1 0.1 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 YxiJ-like protein KID PF02524.9 KFP03645.1 - 0.87 9.9 0.2 0.87 9.9 0.2 2.3 3 0 0 3 3 3 0 KID repeat DUF4603 PF15376.1 KFP03646.1 - 0 2451.8 64.2 0 1765.2 17.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4603) Transglut_i_TM PF14400.1 KFP03646.1 - 0.0055 16.2 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Inactive transglutaminase fused to 7 transmembrane helices SWIRM PF04433.12 KFP03647.1 - 8.4e-05 22.6 0.4 0.00031 20.8 0.0 2.2 2 1 0 2 2 2 1 SWIRM domain Pertussis_S1 PF02917.9 KFP03647.1 - 0.037 13.5 0.0 0.095 12.2 0.0 1.6 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 GrpE PF01025.14 KFP03648.1 - 7.7e-48 162.1 4.2 9.2e-48 161.9 2.9 1.1 1 0 0 1 1 1 1 GrpE DUF2205 PF10224.4 KFP03648.1 - 0.0074 15.8 5.4 0.0098 15.4 3.2 1.6 1 1 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF1993 PF09351.5 KFP03648.1 - 0.026 14.4 2.5 3.8 7.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) LOH1CR12 PF10158.4 KFP03648.1 - 0.051 13.3 1.4 0.074 12.8 1.0 1.4 1 0 0 1 1 1 0 Tumour suppressor protein LRAT PF04970.8 KFP03648.1 - 0.21 11.5 1.1 0.35 10.8 0.8 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Bac_GDH PF05088.7 KFP03648.1 - 0.26 8.6 3.5 0.31 8.3 2.4 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF3391 PF11871.3 KFP03648.1 - 1.4 9.0 6.4 4.4 7.5 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4168 PF13767.1 KFP03648.1 - 2.7 8.6 6.9 0.45 11.1 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) Vma12 PF11712.3 KFP03648.1 - 4.2 7.0 7.2 17 5.0 5.0 1.8 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase IncA PF04156.9 KFP03648.1 - 4.6 6.7 13.1 7.2 6.1 9.1 1.4 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 KFP03648.1 - 5.4 7.4 9.3 0.35 11.2 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 KFP03648.1 - 7.5 5.4 11.0 10 5.0 7.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Hexapep PF00132.19 KFP03649.1 - 6.7e-07 28.5 13.9 1.6e-05 24.1 2.2 4.1 4 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Yeast-kill-tox PF09207.6 KFP03649.1 - 0.022 15.1 0.6 0.032 14.6 0.4 1.3 1 0 0 1 1 1 0 Yeast killer toxin RRM_1 PF00076.17 KFP03650.1 - 6.1e-12 45.0 0.0 8.9e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03650.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03650.1 - 0.00014 21.7 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TFIIE_beta PF02186.10 KFP03651.1 - 1.2e-23 82.8 0.4 3.4e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF1880 PF08976.6 KFP03651.1 - 0.058 13.5 0.4 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Myosin_tail_1 PF01576.14 KFP03651.1 - 0.078 10.6 0.1 0.12 10.0 0.1 1.1 1 0 0 1 1 1 0 Myosin tail NusG PF02357.14 KFP03651.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Transcription termination factor nusG PDZ PF00595.19 KFP03651.1 - 0.12 12.6 0.1 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Shisa PF13908.1 KFP03652.1 - 0.00083 19.5 0.1 0.00087 19.5 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Gemini_mov PF01708.11 KFP03652.1 - 0.066 12.7 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF3753 PF12575.3 KFP03652.1 - 0.12 12.2 3.1 0.19 11.5 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) PurA PF04845.8 KFP03653.1 - 6.2e-106 352.4 0.0 7.4e-106 352.1 0.0 1.0 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein DUF3276 PF11680.3 KFP03653.1 - 2.7e-06 27.2 0.7 0.7 9.7 0.0 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF3276) Orthopox_F8 PF05886.6 KFP03653.1 - 0.99 9.2 5.6 2.3 8.1 3.9 1.6 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Metallophos PF00149.23 KFP03654.1 - 3.5e-42 144.0 0.8 4.5e-42 143.7 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_dim PF02852.17 KFP03655.1 - 7.7e-35 119.2 0.4 1.4e-34 118.4 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFP03655.1 - 2.1e-27 96.3 0.0 3.7e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFP03655.1 - 3.5e-17 62.5 0.2 2.1e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFP03655.1 - 0.0034 17.4 0.0 0.0099 15.9 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFP03655.1 - 0.076 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) EphA2_TM PF14575.1 KFP03656.1 - 1.7e-05 25.0 0.3 2.8e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KFP03656.1 - 0.00028 20.5 0.0 0.00034 20.3 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.1 KFP03656.1 - 0.00031 20.9 0.4 0.00031 20.9 0.2 1.5 2 0 0 2 2 1 1 Wnt and FGF inhibitory regulator FAM163 PF15069.1 KFP03656.1 - 0.0014 19.2 1.9 0.0022 18.5 1.3 1.3 1 0 0 1 1 1 1 FAM163 family Vpu PF00558.14 KFP03656.1 - 0.0015 18.0 0.2 0.0021 17.5 0.2 1.2 1 0 0 1 1 1 1 Vpu protein hEGF PF12661.2 KFP03656.1 - 0.0025 17.7 2.7 0.0025 17.7 1.8 2.9 3 0 0 3 3 2 1 Human growth factor-like EGF Rax2 PF12768.2 KFP03656.1 - 0.0029 16.8 0.0 0.0035 16.6 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity EGF_2 PF07974.8 KFP03656.1 - 0.0032 17.5 6.8 0.0032 17.5 4.7 2.4 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.19 KFP03656.1 - 0.0046 16.8 3.1 0.0046 16.8 2.1 2.1 2 0 0 2 2 2 1 Laminin EGF-like (Domains III and V) Herpes_gE PF02480.11 KFP03656.1 - 0.006 14.8 0.1 0.0083 14.4 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4190 PF13828.1 KFP03656.1 - 0.0077 15.7 0.7 0.011 15.2 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) CD34_antigen PF06365.7 KFP03656.1 - 0.018 14.7 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Protocadherin PF08374.6 KFP03656.1 - 0.019 14.6 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Protocadherin FAM176 PF14851.1 KFP03656.1 - 0.02 14.5 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 FAM176 family DAG1 PF05454.6 KFP03656.1 - 0.026 13.6 0.4 0.031 13.4 0.3 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) FixQ PF05545.6 KFP03656.1 - 0.027 14.1 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF3609 PF12259.3 KFP03656.1 - 0.029 13.0 0.0 0.035 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF1191 PF06697.7 KFP03656.1 - 0.043 12.6 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) 7tm_1 PF00001.16 KFP03656.1 - 0.057 12.5 0.0 0.062 12.4 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PAG PF15347.1 KFP03656.1 - 0.065 12.3 0.0 0.075 12.1 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Tetraspannin PF00335.15 KFP03656.1 - 0.067 12.4 2.4 0.082 12.1 1.6 1.1 1 0 0 1 1 1 0 Tetraspanin family SieB PF14163.1 KFP03656.1 - 0.076 12.5 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B LST1 PF05083.8 KFP03656.1 - 0.087 12.8 0.8 0.087 12.8 0.6 1.6 2 0 0 2 2 2 0 LST-1 protein SIT PF15330.1 KFP03656.1 - 0.092 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT AJAP1_PANP_C PF15298.1 KFP03656.1 - 0.85 9.4 2.7 1.1 9.0 1.8 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Herpes_capsid PF06112.6 KFP03657.1 - 5.9 6.9 6.8 7.4 6.5 4.6 1.3 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein Pkinase PF00069.20 KFP03658.1 - 1e-73 247.7 0.0 1.3e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03658.1 - 7.1e-38 130.1 0.0 3.5e-37 127.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP03658.1 - 2.2e-07 30.1 0.0 1.2e-06 27.6 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP03658.1 - 0.02 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP03658.1 - 0.023 14.4 0.0 0.23 11.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Gag_spuma PF03276.9 KFP03659.1 - 0.067 11.5 0.6 0.097 10.9 0.4 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Herpes_UL87 PF03043.9 KFP03659.1 - 0.11 10.8 0.2 0.12 10.7 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family PA26 PF04636.8 KFP03659.1 - 3.3 6.3 7.4 1.3 7.6 3.5 1.5 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) FHA PF00498.21 KFP03660.1 - 0.00022 21.2 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 FHA domain Alpha_kinase PF02816.13 KFP03661.1 - 1.2e-43 148.9 1.2 1.9e-43 148.3 0.8 1.3 1 0 0 1 1 1 1 Alpha-kinase family DUF2996 PF11210.3 KFP03661.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) AAA_12 PF13087.1 KFP03662.1 - 1.2e-52 178.2 0.0 2.7e-52 177.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFP03662.1 - 1.1e-33 116.8 0.0 1.9e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain zf-GRF PF06839.7 KFP03662.1 - 1.8e-14 53.3 0.1 4.4e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 GRF zinc finger Viral_helicase1 PF01443.13 KFP03662.1 - 4.8e-08 32.8 1.1 0.035 13.6 0.0 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KFP03662.1 - 0.00063 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 KFP03662.1 - 0.0009 18.8 0.0 0.06 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFP03662.1 - 0.0017 18.0 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Toxin_61 PF15538.1 KFP03662.1 - 0.003 17.5 0.0 0.0081 16.1 0.0 1.7 2 0 0 2 2 2 1 Putative toxin 61 UvrD_C PF13361.1 KFP03662.1 - 0.039 13.3 0.2 5.1 6.4 0.1 2.9 2 1 0 3 3 3 0 UvrD-like helicase C-terminal domain RRM_3 PF08777.6 KFP03663.1 - 1.9e-27 95.1 0.1 1.9e-27 95.1 0.1 3.9 4 1 0 4 4 4 2 RNA binding motif La PF05383.12 KFP03663.1 - 1.1e-23 82.7 0.0 2.4e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KFP03663.1 - 8.7e-21 73.3 0.0 1.3e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03663.1 - 4e-17 61.9 0.0 3e-12 46.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03663.1 - 1.1e-12 47.6 0.0 4.8e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRL1 PF13003.2 KFP03664.1 - 3.2e-18 65.8 0.2 6.1e-18 64.9 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L1 Ribosomal_L1 PF00687.16 KFP03664.1 - 6e-08 32.2 0.7 6.6e-08 32.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Gag_MA PF01140.14 KFP03664.1 - 0.041 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Matrix protein (MA), p15 Exo_endo_phos PF03372.18 KFP03665.1 - 1.8e-20 73.9 0.0 2.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KFP03665.1 - 1.1e-14 53.6 17.4 4.4e-10 38.9 1.9 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP03665.1 - 9.3e-11 41.3 11.6 1.8e-10 40.4 6.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KFP03665.1 - 9.9e-07 27.9 18.4 0.017 15.0 0.1 5.8 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFP03665.1 - 0.0029 17.5 17.4 0.3 11.4 0.3 5.3 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFP03665.1 - 0.67 10.2 14.7 3.1 8.1 0.2 4.5 4 0 0 4 4 4 0 Leucine Rich repeat IL8 PF00048.15 KFP03666.1 - 6.8e-17 61.1 0.2 7.6e-17 61.0 0.1 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 KFP03667.1 - 4.2e-17 61.8 0.9 4.5e-17 61.7 0.6 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Gp_UL130 PF11668.3 KFP03667.1 - 0.039 13.4 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Cyclin_N PF00134.18 KFP03669.1 - 1.1e-16 60.5 0.3 1.1e-16 60.5 0.2 2.0 1 1 1 2 2 2 1 Cyclin, N-terminal domain NUDIX PF00293.23 KFP03669.1 - 0.06 12.9 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 NUDIX domain Cyclin_N PF00134.18 KFP03670.1 - 3.1e-25 88.1 0.3 1e-24 86.5 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP03670.1 - 0.0017 18.3 3.1 0.0066 16.3 1.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Septin PF00735.13 KFP03671.1 - 4.2e-99 331.1 1.2 4.2e-99 331.1 0.9 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFP03671.1 - 8.1e-07 29.0 0.4 2e-06 27.7 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFP03671.1 - 0.0011 19.0 0.7 0.0038 17.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 KFP03671.1 - 0.0015 17.9 0.0 0.0046 16.3 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.1 KFP03671.1 - 0.0022 18.0 0.5 0.0064 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 KFP03671.1 - 0.0089 15.4 3.5 1.3 8.4 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KFP03671.1 - 0.015 14.8 0.1 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KFP03671.1 - 0.018 15.4 1.8 0.038 14.4 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KFP03671.1 - 0.039 13.3 2.9 0.1 12.0 2.0 1.9 1 1 0 1 1 1 0 AAA-like domain DUF4478 PF14793.1 KFP03671.1 - 0.059 12.9 0.4 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4478) FtsK_SpoIIIE PF01580.13 KFP03671.1 - 0.12 11.7 3.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 KFP03671.1 - 0.23 11.2 9.1 2.5 7.8 0.1 3.3 2 1 1 3 3 3 0 Dynamin family DUF87 PF01935.12 KFP03671.1 - 0.41 10.4 8.8 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 ABC_tran PF00005.22 KFP03671.1 - 0.98 9.7 6.8 0.21 11.8 0.1 2.6 2 1 0 2 2 2 0 ABC transporter IncA PF04156.9 KFP03671.1 - 2.1 7.9 13.6 3.7 7.1 9.5 1.4 1 0 0 1 1 1 0 IncA protein Fzo_mitofusin PF04799.8 KFP03671.1 - 2.5 7.4 12.4 0.8 9.0 6.2 1.9 2 1 0 2 2 2 0 fzo-like conserved region AAA_11 PF13086.1 KFP03671.1 - 4.1 6.9 12.1 6.5 6.2 7.7 1.7 1 1 0 1 1 1 0 AAA domain Ank_5 PF13857.1 KFP03672.1 - 7.6e-13 48.2 0.3 1.5e-09 37.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP03672.1 - 1.6e-09 37.0 0.7 1e-06 28.2 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFP03672.1 - 2.3e-08 34.3 0.5 3.4e-05 24.2 0.1 2.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFP03672.1 - 2.4e-07 30.9 0.0 8e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFP03672.1 - 0.00012 21.9 0.3 0.034 14.3 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Gal-bind_lectin PF00337.17 KFP03673.1 - 2e-30 104.8 0.0 2.2e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin CD36 PF01130.16 KFP03674.1 - 1.5e-149 498.3 0.2 1.8e-149 498.0 0.2 1.0 1 0 0 1 1 1 1 CD36 family TMEM154 PF15102.1 KFP03674.1 - 1.8 8.2 3.6 0.42 10.3 0.1 1.6 2 0 0 2 2 2 0 TMEM154 protein family Nup54 PF13874.1 KFP03675.1 - 5.2e-49 165.5 4.1 5.2e-49 165.5 2.8 2.1 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 FAST_2 PF08368.7 KFP03675.1 - 0.011 16.0 0.5 0.067 13.5 0.0 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 KRTAP PF11759.3 KFP03675.1 - 1.3 9.3 14.1 3.3 8.0 9.8 1.7 1 0 0 1 1 1 0 Keratin-associated matrix Nucleoporin_FG PF13634.1 KFP03675.1 - 4 7.6 40.6 7.7 6.7 28.2 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region Metallophos PF00149.23 KFP03676.1 - 1.3e-40 138.9 0.0 2.6e-40 137.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 KFP03676.1 - 4.3e-17 60.0 1.9 6.6e-06 25.0 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 KFP03676.1 - 8.9e-14 50.1 2.5 0.00067 18.8 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFP03676.1 - 1.5e-13 50.6 5.1 4.6e-10 39.4 3.5 2.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP03676.1 - 2.5e-13 48.6 1.4 0.0033 17.1 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFP03676.1 - 3.3e-12 45.8 5.7 4.8e-06 26.0 0.0 4.1 3 1 1 4 4 4 2 EF-hand domain pair PPP5 PF08321.7 KFP03676.1 - 2.6e-10 40.1 0.2 9.7e-09 35.1 0.0 3.0 2 1 1 3 3 3 1 PPP5 TPR repeat region IQ PF00612.22 KFP03676.1 - 7.9e-05 21.9 1.5 0.00021 20.6 1.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_4 PF12763.2 KFP03676.1 - 0.00012 21.7 4.3 0.02 14.6 0.2 3.4 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFP03676.1 - 0.00057 19.8 0.5 1.7 8.7 0.2 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFP03676.1 - 0.0058 16.5 0.0 0.99 9.3 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain HIT PF01230.18 KFP03676.1 - 0.12 12.9 0.5 0.98 9.9 0.0 2.7 3 0 0 3 3 3 0 HIT domain SDA1 PF05285.7 KFP03678.1 - 5.4e-69 232.9 41.7 7.6e-37 127.3 3.3 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.7 KFP03678.1 - 7.1e-25 87.0 0.5 7.1e-25 87.0 0.4 2.9 4 0 0 4 4 4 1 NUC130/3NT domain Ig_J_chain PF15097.1 KFP03679.1 - 1.5e-65 218.7 6.6 1.7e-65 218.5 4.6 1.0 1 0 0 1 1 1 1 Immunoglobulin J chain IL8 PF00048.15 KFP03679.1 - 0.02 14.8 3.4 0.94 9.4 0.4 2.5 2 1 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like Sas10 PF09368.5 KFP03680.1 - 5.7e-27 93.7 8.9 5.7e-27 93.7 6.1 2.2 1 1 1 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KFP03680.1 - 5.3e-17 61.7 0.1 5.3e-17 61.7 0.1 1.9 2 1 1 3 3 3 1 Sas10/Utp3/C1D family PRP1_N PF06424.7 KFP03680.1 - 7.2 6.9 13.9 0.57 10.5 4.6 2.1 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal RUN PF02759.14 KFP03681.1 - 7.6e-20 71.0 1.4 2.1e-19 69.6 0.0 2.3 3 0 0 3 3 3 1 RUN domain DUF1664 PF07889.7 KFP03681.1 - 0.0085 15.8 2.1 0.0085 15.8 1.5 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) Macoilin PF09726.4 KFP03681.1 - 0.014 13.7 27.1 0.02 13.2 18.8 1.1 1 0 0 1 1 1 0 Transmembrane protein TMF_DNA_bd PF12329.3 KFP03681.1 - 0.018 14.8 5.3 0.018 14.8 3.7 4.2 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KFP03681.1 - 0.79 8.8 12.5 0.54 9.3 2.7 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ERM PF00769.14 KFP03681.1 - 1.9 7.9 29.6 0.68 9.4 12.9 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 KFP03681.1 - 6.6 6.2 33.8 1.3 8.5 16.1 2.6 1 1 1 2 2 2 0 IncA protein RRM_6 PF14259.1 KFP03682.1 - 2.9e-35 120.0 0.1 2.5e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP03682.1 - 5.3e-17 61.2 0.0 4.2e-06 26.3 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03682.1 - 8.4e-05 22.3 0.1 3.1 7.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mob1_phocein PF03637.12 KFP03683.1 - 1.7e-80 268.8 0.3 2e-80 268.5 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family dNK PF01712.14 KFP03684.1 - 4.6e-46 156.3 1.7 6e-46 155.9 1.2 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 KFP03684.1 - 5.3e-07 29.9 0.0 1.3e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFP03684.1 - 0.00021 21.2 0.2 0.00055 19.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFP03684.1 - 0.00029 20.7 0.0 0.002 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFP03684.1 - 0.0036 16.6 0.2 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_17 PF13207.1 KFP03684.1 - 0.055 14.2 0.4 1.1 10.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain HCO3_cotransp PF00955.16 KFP03685.1 - 2e-246 818.5 8.3 2.5e-246 818.2 5.8 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFP03685.1 - 3.6e-74 249.5 0.4 4.6e-70 236.0 0.0 2.3 1 1 1 2 2 2 2 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.17 KFP03685.1 - 0.015 15.0 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Xan_ur_permease PF00860.15 KFP03685.1 - 4.7 5.6 22.9 0.092 11.2 1.7 3.5 4 0 0 4 4 4 0 Permease family Serum_albumin PF00273.15 KFP03686.1 - 4.6e-62 208.5 13.4 1.8e-29 102.4 1.3 3.3 3 1 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.5 KFP03686.1 - 2.8e-28 97.2 0.8 2.8e-28 97.2 0.6 5.9 5 1 1 6 6 6 3 Vitamin D binding protein, domain III 7tm_1 PF00001.16 KFP03687.1 - 6.2e-61 205.7 13.2 6.2e-61 205.7 9.2 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP03687.1 - 1.4e-08 34.1 13.2 2e-07 30.4 9.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 60KD_IMP PF02096.15 KFP03688.1 - 2e-27 96.1 0.0 2.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein HlyC PF02794.11 KFP03688.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RTX toxin acyltransferase family Ank_2 PF12796.2 KFP03689.1 - 1.2e-205 666.6 65.7 2.6e-25 88.5 0.7 12.2 3 3 9 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 KFP03689.1 - 4.3e-178 569.0 64.3 8.4e-11 41.1 0.0 25.4 25 0 0 25 25 25 24 Ankyrin repeat Ank_4 PF13637.1 KFP03689.1 - 6.6e-140 453.3 17.0 5.9e-13 48.9 0.0 14.6 9 4 3 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP03689.1 - 4.6e-120 379.3 38.3 9.9e-05 22.2 0.1 25.2 25 0 0 25 25 25 24 Ankyrin repeat Ank_5 PF13857.1 KFP03689.1 - 1.6e-107 349.1 52.0 8e-10 38.6 0.0 23.6 3 3 22 25 25 25 25 Ankyrin repeats (many copies) KH_1 PF00013.24 KFP03689.1 - 2e-14 52.9 3.8 4.7e-14 51.7 2.6 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFP03689.1 - 7.9e-11 41.3 5.3 2.3e-10 39.8 3.7 1.9 1 0 0 1 1 1 1 KH domain Serum_albumin PF00273.15 KFP03690.1 - 4.9e-145 478.8 34.7 2.2e-56 190.1 6.5 3.0 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.5 KFP03690.1 - 8.9e-07 28.4 11.6 0.54 9.9 0.0 6.3 6 1 0 6 6 6 4 Vitamin D binding protein, domain III CYTL1 PF15153.1 KFP03690.1 - 0.1 12.3 0.2 0.1 12.3 0.1 2.9 3 1 0 3 3 3 0 Cytokine-like protein 1 Serum_albumin PF00273.15 KFP03691.1 - 1.8e-129 428.2 37.4 2.1e-51 173.9 5.9 3.1 3 0 0 3 3 3 3 Serum albumin family VitD-bind_III PF09164.5 KFP03691.1 - 5.1e-07 29.2 8.7 0.0047 16.4 0.4 4.7 4 0 0 4 4 4 2 Vitamin D binding protein, domain III RA PF00788.18 KFP03692.1 - 1.2e-12 48.1 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFP03692.1 - 0.0073 16.2 0.1 0.022 14.6 0.0 2.0 1 1 0 1 1 1 1 Ras-binding domain of Byr2 CCDC-167 PF15188.1 KFP03692.1 - 0.035 14.0 0.0 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 YusW PF14039.1 KFP03692.1 - 0.036 14.3 0.4 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 YusW-like protein RecO_C PF02565.10 KFP03692.1 - 0.04 13.7 0.2 0.19 11.6 0.0 2.0 1 1 1 2 2 2 0 Recombination protein O C terminal IL8 PF00048.15 KFP03693.1 - 3.6e-20 71.7 0.1 4.6e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like IL8 PF00048.15 KFP03694.1 - 1.4e-20 72.9 0.4 1.8e-20 72.6 0.3 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like bPH_6 PF10756.4 KFP03694.1 - 0.017 15.0 0.0 0.056 13.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial PH domain THF_DHG_CYH_C PF02882.14 KFP03695.1 - 7.2e-62 207.2 4.1 9.7e-62 206.7 2.8 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KFP03695.1 - 4.2e-39 133.1 0.2 6.2e-39 132.6 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain EGF PF00008.22 KFP03696.1 - 0.0029 17.5 3.6 0.006 16.5 2.5 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFP03696.1 - 0.0039 17.1 0.5 0.0094 15.9 0.4 1.7 1 0 0 1 1 1 1 Human growth factor-like EGF Rad60-SLD_2 PF13881.1 KFP03696.1 - 0.073 12.9 0.1 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4187 PF13821.1 KFP03696.1 - 0.12 11.9 1.5 0.22 11.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) SKG6 PF08693.5 KFP03696.1 - 0.14 11.4 0.3 0.31 10.3 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Laminin_EGF PF00053.19 KFP03696.1 - 0.32 10.9 3.5 0.68 9.9 2.4 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFP03696.1 - 2.7 8.2 5.6 12 6.1 3.9 2.1 1 1 0 1 1 1 0 EGF-like domain EGF PF00008.22 KFP03697.1 - 3.2e-06 27.0 3.0 6.3e-06 26.0 2.1 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFP03697.1 - 0.0094 15.9 1.4 0.0094 15.9 1.0 2.2 2 0 0 2 2 2 1 Human growth factor-like EGF Rifin_STEVOR PF02009.11 KFP03697.1 - 0.03 13.9 1.2 0.038 13.6 0.8 1.1 1 0 0 1 1 1 0 Rifin/stevor family 7TM_GPCR_Srv PF10323.4 KFP03697.1 - 0.043 12.9 0.1 0.045 12.8 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Oxidored_q2 PF00420.19 KFP03697.1 - 0.05 13.2 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF1180 PF06679.7 KFP03697.1 - 0.065 13.1 0.6 0.085 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF912 PF06024.7 KFP03697.1 - 0.069 13.1 0.2 0.095 12.7 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EGF_2 PF07974.8 KFP03697.1 - 0.076 13.1 3.3 0.19 11.9 2.3 1.7 1 1 0 1 1 1 0 EGF-like domain DUF3481 PF11980.3 KFP03697.1 - 0.077 12.8 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) InaF-motif PF15018.1 KFP03697.1 - 1.2 8.6 5.4 2 7.9 3.7 1.4 1 0 0 1 1 1 0 TRP-interacting helix EGF PF00008.22 KFP03698.1 - 0.00026 20.9 3.4 0.00047 20.0 2.4 1.5 1 0 0 1 1 1 1 EGF-like domain Chordopox_A33R PF05966.7 KFP03698.1 - 0.0056 15.4 0.7 0.0056 15.4 0.5 1.6 1 1 0 1 1 1 1 Chordopoxvirus A33R protein EphA2_TM PF14575.1 KFP03698.1 - 0.0095 16.3 2.7 0.018 15.4 0.2 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 KFP03698.1 - 0.02 14.5 0.2 0.02 14.5 0.1 1.6 2 0 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.6 KFP03698.1 - 0.076 12.5 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Podoplanin Protocadherin PF08374.6 KFP03698.1 - 0.078 12.6 0.3 0.078 12.6 0.2 2.1 2 0 0 2 2 2 0 Protocadherin DUF3377 PF11857.3 KFP03698.1 - 0.09 12.4 0.4 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EGF_2 PF07974.8 KFP03698.1 - 0.1 12.7 5.1 0.19 11.8 3.5 1.5 1 0 0 1 1 1 0 EGF-like domain FtsL PF04999.8 KFP03698.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Cell division protein FtsL Uso1_p115_head PF04869.9 KFP03699.1 - 1.4e-67 227.6 0.1 1.4e-67 227.6 0.1 2.9 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KFP03699.1 - 9.4e-21 74.1 18.9 9.4e-21 74.1 13.1 3.9 3 1 2 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region Leu_zip PF15294.1 KFP03699.1 - 0.0003 20.0 3.5 0.0003 20.0 2.4 4.2 3 1 1 4 4 4 2 Leucine zipper DUF812 PF05667.6 KFP03699.1 - 0.16 10.4 38.9 0.016 13.7 18.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.3 KFP03699.1 - 0.61 9.8 49.4 0.013 15.1 11.5 4.6 3 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding NTF2 PF02136.15 KFP03700.1 - 2.7e-32 111.5 0.1 4.5e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KFP03700.1 - 9.4e-15 54.0 0.1 2.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03700.1 - 2.5e-10 40.1 0.1 5.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03700.1 - 0.005 16.6 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 KFP03700.1 - 6.5 6.0 24.8 8.3 5.6 17.2 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KFP03701.1 - 1.6e-40 138.8 0.0 3.2e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03701.1 - 6.3e-25 87.7 0.0 6.3e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP03701.1 - 3.6e-07 29.4 1.0 1.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP03701.1 - 0.021 14.5 0.1 0.021 14.5 0.0 2.8 2 2 1 3 3 3 0 Phosphotransferase enzyme family DUF1151 PF06625.6 KFP03701.1 - 0.36 10.5 5.3 0.92 9.2 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) BMP2K_C PF15282.1 KFP03702.1 - 3.9e-79 265.9 10.7 3.9e-79 265.9 7.4 2.6 2 2 0 2 2 2 2 BMP-2-inducible protein kinase C-terminus HlyIII PF03006.15 KFP03703.1 - 4.1e-44 150.6 25.5 4.8e-44 150.3 17.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ant_C PF05586.6 KFP03704.1 - 9.9e-42 141.3 0.5 9.9e-42 141.3 0.3 1.5 2 0 0 2 2 2 1 Anthrax receptor C-terminus region Prolactin_RP PF15172.1 KFP03704.1 - 0.2 10.8 1.8 0.98 8.6 0.3 2.3 2 0 0 2 2 2 0 Prolactin-releasing peptide 4HBT_3 PF13622.1 KFP03704.1 - 0.22 11.2 2.2 0.26 10.9 1.5 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily VWA PF00092.23 KFP03705.1 - 4.4e-10 39.5 0.0 4.7e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFP03705.1 - 3.1e-05 24.1 0.0 3.3e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain FGF PF00167.13 KFP03707.1 - 2.9e-30 104.5 0.0 3.2e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor DUF4464 PF14713.1 KFP03708.1 - 1.6e-72 243.7 0.0 1.8e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) SHOCT PF09851.4 KFP03708.1 - 0.48 9.9 3.0 1.2 8.6 2.1 1.7 1 0 0 1 1 1 0 Short C-terminal domain TGF_beta PF00019.15 KFP03709.1 - 8.3e-15 54.9 0.1 2.4e-14 53.5 0.1 1.8 1 0 0 1 1 1 1 Transforming growth factor beta like domain Retrotrans_gag PF03732.12 KFP03710.1 - 0.00072 19.5 2.2 0.0012 18.8 0.3 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Apolipoprotein PF01442.13 KFP03710.1 - 0.0059 16.1 2.1 0.014 14.9 0.6 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain HCR PF07111.7 KFP03710.1 - 0.05 11.6 0.3 0.07 11.1 0.2 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF842 PF05811.8 KFP03710.1 - 0.053 12.9 0.4 0.28 10.6 0.2 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF327 PF03885.8 KFP03710.1 - 0.069 12.9 0.2 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF327) SYCE1 PF15233.1 KFP03710.1 - 0.13 12.2 3.3 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Ribonuc_2-5A PF06479.7 KFP03710.1 - 0.18 11.6 1.3 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A UPAR_LY6 PF00021.16 KFP03713.1 - 1.3e-06 28.7 18.0 1.6e-06 28.4 12.4 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Activin_recp PF01064.18 KFP03713.1 - 0.023 15.3 14.7 0.03 14.9 10.2 1.2 1 0 0 1 1 1 0 Activin types I and II receptor domain Toxin_1 PF00087.16 KFP03713.1 - 0.073 13.4 15.4 0.14 12.5 10.7 1.5 1 1 0 1 1 1 0 Snake toxin UPAR_LY6 PF00021.16 KFP03714.1 - 6.4e-06 26.5 10.5 7.8e-06 26.2 7.2 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain BAMBI PF06211.7 KFP03714.1 - 4.4 7.3 7.0 5.9 6.9 4.9 1.1 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain BAMBI PF06211.7 KFP03715.1 - 0.009 15.9 0.5 0.011 15.6 0.3 1.2 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain UPAR_LY6 PF00021.16 KFP03715.1 - 0.017 15.5 0.5 0.023 15.1 0.3 1.2 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Activin_recp PF01064.18 KFP03715.1 - 0.11 13.1 1.9 0.18 12.4 1.3 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain Herpes_LAMP2 PF06126.6 KFP03715.1 - 0.14 10.5 1.5 0.15 10.4 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 UPAR_LY6 PF00021.16 KFP03716.1 - 1.9e-13 50.6 9.3 2.3e-13 50.3 6.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 KFP03716.1 - 0.0095 16.2 7.7 0.016 15.5 5.4 1.4 1 1 0 1 1 1 1 Snake toxin UPAR_LY6 PF00021.16 KFP03717.1 - 1.3e-09 38.3 17.2 1.7e-09 37.9 11.9 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Toxin_1 PF00087.16 KFP03717.1 - 0.0067 16.7 14.8 0.012 15.9 10.3 1.5 1 0 0 1 1 1 1 Snake toxin UPAR_LY6 PF00021.16 KFP03718.1 - 2.6e-08 34.1 18.1 3.2e-08 33.8 12.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain DUF1644 PF07800.7 KFP03718.1 - 5 6.9 11.5 1.1e+02 2.6 7.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) UPAR_LY6 PF00021.16 KFP03719.1 - 4e-08 33.5 15.2 4.9e-08 33.2 10.5 1.1 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Topoisom_I_N PF02919.10 KFP03720.1 - 1.4e-101 338.3 5.9 1.4e-101 338.3 4.1 3.9 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KFP03720.1 - 6.8e-87 290.4 7.0 1.7e-86 289.1 4.9 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KFP03720.1 - 6.6e-33 112.1 0.1 6.6e-33 112.1 0.1 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain Hanta_nucleocap PF00846.13 KFP03720.1 - 0.015 14.0 7.1 0.027 13.1 4.9 1.3 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein DUF641 PF04859.7 KFP03720.1 - 5.7 6.7 18.9 0.063 13.0 3.5 3.4 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) BRO1 PF03097.13 KFP03721.1 - 8.9e-115 383.4 0.2 1.5e-114 382.6 0.1 1.3 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.11 KFP03721.1 - 1.3e-15 56.8 4.6 2.6e-15 55.8 3.2 1.6 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.19 KFP03721.1 - 4.8e-14 52.2 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP03721.1 - 3.3e-05 23.6 0.0 9.5e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 PDZ domain Fmp27_WPPW PF10359.4 KFP03721.1 - 0.055 11.8 2.3 0.099 11.0 1.6 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tricorn_PDZ PF14685.1 KFP03721.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain RVT_1 PF00078.22 KFP03723.1 - 1.3e-12 47.5 0.0 2.5e-12 46.6 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AA_kinase PF00696.23 KFP03724.1 - 3.9e-34 118.2 0.1 9.5e-34 117.0 0.1 1.6 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.17 KFP03724.1 - 9.9e-12 43.9 0.1 9.1e-09 34.1 0.0 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family 7tm_1 PF00001.16 KFP03725.1 - 3.5e-50 170.5 14.7 4.2e-50 170.2 10.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP03725.1 - 6.6e-08 32.0 13.0 7.8e-08 31.7 9.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP03725.1 - 3.3e-07 29.7 7.4 3.3e-07 29.7 5.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFP03725.1 - 1.1e-05 24.7 13.1 0.0001 21.5 9.1 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7tm_4 PF13853.1 KFP03725.1 - 0.42 10.4 13.4 0.11 12.2 4.2 3.0 2 1 1 3 3 3 0 Olfactory receptor Homeobox PF00046.24 KFP03726.1 - 4.3e-22 77.4 1.0 6.8e-22 76.8 0.7 1.3 1 0 0 1 1 1 1 Homeobox domain PKK PF12474.3 KFP03726.1 - 0.0013 18.4 2.0 0.0025 17.5 1.4 1.4 1 0 0 1 1 1 1 Polo kinase kinase Homez PF11569.3 KFP03726.1 - 0.025 13.6 0.2 0.054 12.5 0.1 1.6 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Pilt PF15453.1 KFP03726.1 - 0.17 11.5 4.6 0.19 11.4 3.2 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions ABC_trans_N PF14510.1 KFP03726.1 - 0.38 10.8 3.8 0.49 10.5 2.7 1.5 1 1 0 1 1 1 0 ABC-transporter extracellular N-terminal MMtag PF10159.4 KFP03726.1 - 0.83 9.7 6.5 1.1 9.3 4.2 1.7 1 1 0 1 1 1 0 Kinase phosphorylation protein Exo_endo_phos PF03372.18 KFP03727.1 - 6.7e-09 36.0 0.0 8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UQ_con PF00179.21 KFP03727.1 - 0.048 13.0 0.1 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme PCNA_N PF00705.13 KFP03727.1 - 0.082 12.4 0.4 0.25 10.8 0.3 1.8 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain RWD PF05773.17 KFP03727.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 RWD domain Pkinase PF00069.20 KFP03728.1 - 3.4e-60 203.3 0.9 5.9e-60 202.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03728.1 - 5.7e-35 120.6 0.1 8.7e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP03728.1 - 4.8e-11 42.1 0.0 6.2e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP03728.1 - 0.0037 16.3 0.2 0.0071 15.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP03728.1 - 0.0061 16.3 0.2 0.012 15.3 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family BNIP3 PF06553.7 KFP03730.1 - 4.2e-75 251.4 4.5 5e-75 251.2 3.1 1.0 1 0 0 1 1 1 1 BNIP3 WD40 PF00400.27 KFP03731.1 - 7.7e-12 44.6 4.6 0.51 10.3 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Y_phosphatase2 PF03162.8 KFP03731.1 - 0.0027 17.0 0.3 0.17 11.2 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family FF PF01846.14 KFP03732.1 - 2.4e-21 75.4 11.5 2.5e-11 43.3 0.6 2.4 2 0 0 2 2 2 2 FF domain WW PF00397.21 KFP03732.1 - 3.6e-05 23.5 0.1 3.6e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 WW domain HEAT PF02985.17 KFP03733.1 - 1.7e-34 114.7 12.0 0.0023 17.8 0.0 12.0 13 0 0 13 13 12 7 HEAT repeat HEAT_EZ PF13513.1 KFP03733.1 - 1.7e-28 98.3 0.2 5.3e-10 39.4 0.0 10.1 8 2 3 11 11 11 5 HEAT-like repeat HEAT_2 PF13646.1 KFP03733.1 - 6e-23 80.9 0.0 1.2e-05 25.5 0.0 6.5 3 2 4 8 8 8 7 HEAT repeats Arm PF00514.18 KFP03733.1 - 9.4e-16 56.9 7.5 0.0085 15.8 0.0 7.9 9 0 0 9 9 8 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 KFP03733.1 - 7.4e-15 54.6 0.5 5.8e-14 51.7 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KFP03733.1 - 8.3e-15 54.9 1.0 0.08 13.3 0.0 6.4 4 2 2 6 6 6 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFP03733.1 - 2.3e-13 50.3 5.4 0.0025 17.7 0.4 5.3 3 2 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KFP03733.1 - 4.6e-08 31.8 4.0 0.044 12.1 0.2 4.5 2 2 0 4 4 4 3 Adaptin N terminal region Dopey_N PF04118.9 KFP03733.1 - 6e-05 21.9 0.1 0.00023 20.0 0.1 1.9 1 0 0 1 1 1 1 Dopey, N-terminal UNC45-central PF11701.3 KFP03733.1 - 0.00016 21.3 8.0 0.011 15.3 0.4 4.0 6 0 0 6 6 6 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 KFP03733.1 - 0.00016 21.1 1.7 0.49 9.7 0.0 4.3 4 2 1 5 5 5 1 CLASP N terminal Proteasom_PSMB PF10508.4 KFP03733.1 - 0.00046 18.5 1.0 0.4 8.8 0.0 4.1 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 KFP03733.1 - 0.017 13.8 6.5 1.3 7.6 0.1 4.2 4 2 0 4 4 4 0 RNAPII transcription regulator C-terminal TAFH PF07531.9 KFP03733.1 - 0.29 10.7 2.9 12 5.6 0.0 4.2 5 0 0 5 5 5 0 NHR1 homology to TAF HSP20 PF00011.16 KFP03734.1 - 2.3e-17 62.6 0.0 3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YabP PF07873.6 KFP03734.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 YabP family SRRM_C PF15230.1 KFP03735.1 - 3.8e-25 87.7 27.9 3.8e-25 87.7 19.4 9.2 4 3 5 9 9 9 1 Serine/arginine repetitive matrix protein C-terminus Sds3 PF08598.6 KFP03736.1 - 5.3e-13 48.9 12.3 6.7e-11 42.1 8.5 2.2 1 1 0 1 1 1 1 Sds3-like Retrotrans_gag PF03732.12 KFP03736.1 - 0.062 13.3 3.6 0.14 12.2 2.5 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein SseC PF04888.7 KFP03736.1 - 2 7.6 9.5 2.6 7.2 6.6 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family IncA PF04156.9 KFP03736.1 - 3.9 7.0 7.4 6.7 6.2 5.1 1.3 1 0 0 1 1 1 0 IncA protein PBP PF01161.15 KFP03737.1 - 3.2e-26 91.9 0.1 3.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Rootletin PF15035.1 KFP03738.1 - 0.017 15.0 5.9 0.021 14.8 4.1 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion OrfB_IS605 PF01385.14 KFP03738.1 - 0.02 14.2 2.5 0.023 14.0 1.7 1.1 1 0 0 1 1 1 0 Probable transposase NAP PF00956.13 KFP03738.1 - 0.042 12.9 1.0 0.038 13.0 0.7 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Atg14 PF10186.4 KFP03738.1 - 0.044 12.7 3.3 0.048 12.6 2.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 KFP03738.1 - 0.057 13.4 5.0 0.059 13.3 3.5 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2130 PF09903.4 KFP03738.1 - 0.079 11.6 0.2 0.096 11.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Tymo_45kd_70kd PF03251.8 KFP03738.1 - 0.13 10.9 0.7 0.16 10.6 0.5 1.0 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein OmpH PF03938.9 KFP03738.1 - 0.13 12.1 3.3 0.17 11.8 2.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YgaB PF14182.1 KFP03738.1 - 0.17 12.1 4.9 0.5 10.6 2.8 1.9 1 1 1 2 2 2 0 YgaB-like protein ACCA PF03255.9 KFP03738.1 - 0.29 10.6 1.3 0.31 10.6 0.9 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DEAD PF00270.24 KFP03739.1 - 3.9e-47 159.8 0.0 8e-47 158.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP03739.1 - 6.6e-20 70.7 0.0 1.5e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KFP03739.1 - 6.7e-20 70.6 7.4 1.7e-19 69.4 5.1 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 KFP03739.1 - 1.5e-07 31.3 1.2 8.5e-07 28.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Ion_trans PF00520.26 KFP03740.1 - 1.5e-48 164.7 51.4 5.6e-29 100.8 15.9 2.3 2 0 0 2 2 2 2 Ion transport protein OppC_N PF12911.2 KFP03740.1 - 0.034 13.5 13.4 0.86 9.0 1.2 4.6 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF1474 PF07342.6 KFP03740.1 - 0.06 13.5 0.4 6 7.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1474) DUF1628 PF07790.6 KFP03740.1 - 0.14 12.9 0.1 1.2 9.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) Na_Ca_ex PF01699.19 KFP03741.1 - 8.9e-39 132.2 37.1 2.9e-24 85.2 8.6 3.1 3 1 0 3 3 3 2 Sodium/calcium exchanger protein Cyt_c_ox_IV PF12270.3 KFP03741.1 - 0.025 14.3 0.1 0.025 14.3 0.1 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Phospholip_B PF04916.8 KFP03742.1 - 1.6e-163 544.8 0.0 1.8e-163 544.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B PALP PF00291.20 KFP03743.1 - 6.3e-42 143.8 0.0 6.8e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.16 KFP03743.1 - 0.00035 20.1 0.1 0.00047 19.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KFP03743.1 - 0.0074 15.1 0.2 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AIRC PF00731.15 KFP03743.1 - 0.023 13.9 0.1 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 AIR carboxylase SIS_2 PF13580.1 KFP03743.1 - 0.036 13.7 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 SIS domain FAD_binding_2 PF00890.19 KFP03743.1 - 0.038 12.8 0.2 0.056 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KFP03743.1 - 0.044 12.8 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DegT_DnrJ_EryC1 PF01041.12 KFP03743.1 - 0.06 12.3 0.1 0.075 12.0 0.1 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family LIM PF00412.17 KFP03744.1 - 2.2e-27 94.8 22.3 1.8e-18 66.3 1.2 2.2 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFP03744.1 - 4.9e-10 38.8 0.1 9.4e-10 37.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain PMSI1 PF15322.1 KFP03744.1 - 0.009 15.1 0.5 0.014 14.5 0.3 1.2 1 0 0 1 1 1 1 Protein missing in infertile sperm 1, putative Homeobox_KN PF05920.6 KFP03744.1 - 0.091 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain RRM_1 PF00076.17 KFP03746.1 - 4.5e-80 263.2 2.8 9e-19 66.8 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03746.1 - 9.1e-75 246.6 0.7 8.9e-18 64.0 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03746.1 - 1.1e-45 153.3 0.1 1.6e-11 43.8 0.0 6.3 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP03746.1 - 2.1e-05 24.2 8.9 0.46 10.3 0.0 6.5 6 2 0 6 6 6 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFP03746.1 - 0.00017 21.2 0.1 3.3 7.5 0.0 4.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KFP03746.1 - 0.0014 18.3 0.1 1.1 9.1 0.0 4.5 5 1 0 5 5 5 1 Limkain b1 CTD PF12815.2 KFP03747.1 - 0.23 11.8 18.3 2 8.8 12.7 2.0 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 CTD PF12815.2 KFP03748.1 - 0.099 13.0 33.8 1.1e+03 -0.1 23.5 2.5 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 T-box PF00907.17 KFP03749.1 - 4.9e-43 146.7 0.1 9.1e-37 126.3 0.0 2.2 2 0 0 2 2 2 2 T-box DUF4083 PF13314.1 KFP03749.1 - 0.021 14.6 2.4 0.043 13.6 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Glycophorin_A PF01102.13 KFP03749.1 - 0.038 13.7 0.3 0.038 13.7 0.2 2.2 2 0 0 2 2 2 0 Glycophorin A CCSMST1 PF15013.1 KFP03749.1 - 0.048 13.5 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 CCSMST1 family DUF912 PF06024.7 KFP03749.1 - 0.081 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 KFP03749.1 - 0.12 12.0 0.2 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family TraV PF09676.5 KFP03749.1 - 0.24 12.1 8.7 0.21 12.2 1.7 2.5 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) T-box PF00907.17 KFP03750.1 - 5.6e-77 257.3 0.4 6.2e-77 257.2 0.3 1.0 1 0 0 1 1 1 1 T-box Med13_C PF06333.7 KFP03751.1 - 4.1e-135 450.6 0.1 4.1e-135 450.6 0.1 2.9 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KFP03751.1 - 2e-104 349.5 0.0 2e-104 349.5 0.0 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal DUF2054 PF10218.4 KFP03752.1 - 2.3e-53 179.5 17.0 3e-53 179.2 11.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) APS-reductase_C PF12139.3 KFP03752.1 - 0.021 14.9 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit F-box-like PF12937.2 KFP03754.1 - 3.5e-13 49.0 0.1 9.6e-13 47.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 KFP03754.1 - 3.6e-10 39.3 3.2 0.014 15.2 0.1 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat F-box PF00646.28 KFP03754.1 - 2.6e-08 33.2 0.0 8.5e-08 31.6 0.0 1.9 2 0 0 2 2 2 1 F-box domain BBS2_Mid PF14783.1 KFP03754.1 - 0.0017 18.1 0.0 0.054 13.2 0.0 2.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region EF-hand_7 PF13499.1 KFP03755.1 - 6.5e-10 39.0 7.2 3.2e-05 23.9 2.0 2.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP03755.1 - 2.8e-08 32.4 0.2 2.5e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KFP03755.1 - 6.1e-06 25.6 0.5 5e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KFP03755.1 - 0.00011 21.3 0.1 0.00042 19.5 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFP03755.1 - 0.00035 20.1 2.5 0.01 15.4 0.5 2.4 2 0 0 2 2 2 1 EF-hand domain pair DUF4196 PF13846.1 KFP03755.1 - 0.052 13.8 0.1 0.081 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) Dna2 PF08696.6 KFP03755.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA replication factor Dna2 Transglut_core2 PF13369.1 KFP03756.1 - 3e-41 140.4 0.0 4.9e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.6 KFP03756.1 - 2.1e-27 94.9 0.3 5.5e-27 93.6 0.0 1.9 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like TPR_16 PF13432.1 KFP03756.1 - 0.032 14.9 0.0 0.06 14.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 KFP03757.1 - 1.3e-48 165.3 0.0 1.6e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP03757.1 - 1.1e-43 149.2 0.0 1.6e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C1_1 PF00130.17 KFP03757.1 - 2.2e-05 24.1 12.1 5.5e-05 22.8 8.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KFP03757.1 - 0.00036 19.5 0.0 0.0015 17.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP03757.1 - 0.022 13.8 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP03757.1 - 0.024 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KFP03757.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rep_fac_C PF08542.6 KFP03758.1 - 5.5e-23 80.7 0.2 9.8e-23 79.9 0.1 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KFP03758.1 - 1.2e-15 57.8 0.0 2.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KFP03758.1 - 1.2e-13 51.0 0.0 1.4e-11 44.3 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 KFP03758.1 - 5e-07 29.9 0.2 0.0056 16.8 0.0 2.7 2 1 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KFP03758.1 - 1.1e-06 28.3 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFP03758.1 - 5.6e-06 26.4 0.0 1.7e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 KFP03758.1 - 1.6e-05 24.6 0.0 0.00051 19.6 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFP03758.1 - 2.9e-05 23.9 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KFP03758.1 - 3.7e-05 22.6 0.0 0.065 11.8 0.0 2.3 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 KFP03758.1 - 9.1e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KFP03758.1 - 0.00016 21.2 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 KFP03758.1 - 0.0005 19.8 0.1 0.003 17.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 KFP03758.1 - 0.00081 18.9 0.0 0.033 13.6 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KFP03758.1 - 0.0027 17.1 0.0 0.049 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KFP03758.1 - 0.0028 16.9 0.4 0.17 11.0 0.0 2.6 2 1 0 3 3 3 1 PhoH-like protein IstB_IS21 PF01695.12 KFP03758.1 - 0.0032 16.8 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 KFP03758.1 - 0.0038 16.3 0.0 0.0083 15.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 KFP03758.1 - 0.0038 16.8 0.1 0.24 10.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFP03758.1 - 0.0082 15.9 0.0 0.055 13.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TIP49 PF06068.8 KFP03758.1 - 0.011 14.4 0.0 0.21 10.2 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus AAA_10 PF12846.2 KFP03758.1 - 0.013 14.9 0.0 3.5 6.9 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 KFP03758.1 - 0.044 12.9 0.0 0.64 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFP03758.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 KFP03758.1 - 0.081 11.6 0.0 0.62 8.7 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF815 PF05673.8 KFP03758.1 - 0.1 11.4 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 KFP03758.1 - 0.11 11.9 0.0 0.58 9.6 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 KFP03758.1 - 0.14 12.0 0.1 0.6 9.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain WD40 PF00400.27 KFP03759.1 - 1.6e-31 107.0 16.1 9.9e-10 37.9 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat SOCS_box PF07525.11 KFP03759.1 - 5.5e-11 42.1 1.1 9.9e-11 41.3 0.8 1.4 1 0 0 1 1 1 1 SOCS box Nup160 PF11715.3 KFP03759.1 - 0.0084 14.2 0.3 0.02 13.0 0.2 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFP03759.1 - 0.06 12.0 0.0 2.8 6.6 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like zf-RING_2 PF13639.1 KFP03760.1 - 1.3e-07 31.2 1.9 4e-07 29.7 1.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP03760.1 - 2.3e-06 27.6 0.5 6.2e-06 26.2 0.2 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP03760.1 - 4.9e-06 26.1 0.7 1.3e-05 24.7 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP03760.1 - 0.00036 20.2 0.9 0.00087 18.9 0.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFP03760.1 - 0.0018 18.0 1.7 0.0035 17.1 0.5 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-LITAF-like PF10601.4 KFP03760.1 - 0.0026 17.5 0.3 0.0026 17.5 0.2 1.9 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain zf-C3HC4_2 PF13923.1 KFP03760.1 - 0.0028 17.6 5.7 0.011 15.7 0.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP03760.1 - 0.0045 16.6 1.9 0.026 14.1 1.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KFP03760.1 - 0.064 12.9 1.3 0.097 12.3 0.1 1.9 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 KFP03760.1 - 0.12 12.0 3.5 3.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KFP03760.1 - 0.25 10.9 2.2 0.28 10.7 0.3 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFP03760.1 - 0.49 10.3 4.1 0.34 10.8 0.7 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING ADK_lid PF05191.9 KFP03760.1 - 5.4 6.7 11.5 21 4.8 0.1 4.2 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-RanBP PF00641.13 KFP03761.1 - 5.7e-13 47.7 7.4 8.7e-13 47.1 5.1 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KFP03761.1 - 2.5e-10 39.8 0.1 9.9e-10 37.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP03761.1 - 1.7e-08 34.3 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03761.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.15 KFP03762.1 - 8.7e-173 575.4 15.4 1.1e-172 575.0 10.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFP03762.1 - 6.7e-37 127.0 8.9 1.6e-35 122.5 0.3 4.1 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.5 KFP03762.1 - 2.3e-36 124.1 0.1 6.5e-36 122.6 0.1 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.1 KFP03762.1 - 6.9e-24 83.9 5.1 1.1e-06 28.8 0.0 5.6 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.17 KFP03762.1 - 4.2e-14 51.2 6.2 0.0038 17.1 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Alpha_adaptinC2 PF02883.15 KFP03762.1 - 3.3e-10 40.2 0.1 8.5e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd3 PF12719.2 KFP03762.1 - 4.7e-07 29.0 4.8 2.6e-05 23.3 0.2 2.6 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 KFP03762.1 - 8.6e-07 28.5 5.5 0.0039 16.9 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KFP03762.1 - 3.7e-05 23.2 1.8 0.9 8.8 0.1 4.5 2 2 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 KFP03762.1 - 0.00011 22.6 7.7 1.3 9.6 0.0 6.7 6 2 3 9 9 8 1 HEAT-like repeat MOR2-PAG1_C PF14225.1 KFP03762.1 - 0.0013 18.5 4.2 2.6 7.7 0.0 3.3 2 1 1 3 3 3 2 Cell morphogenesis C-terminal Atx10homo_assoc PF09759.4 KFP03762.1 - 0.0077 15.9 0.1 1.3 8.7 0.0 3.2 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Cohesin_HEAT PF12765.2 KFP03762.1 - 0.012 15.5 0.0 23 5.0 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Alpha_adaptin_C PF02296.11 KFP03762.1 - 0.049 13.5 1.1 0.12 12.3 0.0 2.3 3 0 0 3 3 2 0 Alpha adaptin AP2, C-terminal domain FANCI_S2 PF14676.1 KFP03762.1 - 0.11 12.4 1.1 2.1 8.2 0.2 3.3 3 2 1 4 4 4 0 FANCI solenoid 2 Filament PF00038.16 KFP03763.1 - 6.3e-38 131.0 15.9 6.3e-38 131.0 11.0 2.4 2 0 0 2 2 2 1 Intermediate filament protein FimP PF09766.4 KFP03764.1 - 1.2e-133 445.5 6.3 1.9e-133 444.9 4.4 1.2 1 0 0 1 1 1 1 Fms-interacting protein NIPSNAP PF07978.8 KFP03765.1 - 1.7e-10 40.7 1.8 6.4e-07 29.2 0.1 2.9 2 1 0 2 2 2 2 NIPSNAP AA_permease PF00324.16 KFP03766.1 - 1.6e-149 498.2 38.3 1.9e-149 498.0 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFP03766.1 - 1.1e-20 73.5 43.4 1.7e-20 72.9 30.1 1.2 1 0 0 1 1 1 1 Amino acid permease NTPase_I-T PF01931.13 KFP03767.1 - 2.2e-07 30.7 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF84 Laminin_EGF PF00053.19 KFP03768.1 - 2.8e-46 155.2 327.1 0.0033 17.3 4.7 18.2 5 3 13 18 18 18 16 Laminin EGF-like (Domains III and V) hEGF PF12661.2 KFP03768.1 - 3.3e-16 58.1 306.2 0.0014 18.5 3.6 32.7 34 0 0 34 34 34 20 Human growth factor-like EGF EGF_2 PF07974.8 KFP03768.1 - 3.9e-08 33.3 386.2 0.0037 17.3 12.2 25.4 20 10 8 28 28 28 14 EGF-like domain Baculo_11_kDa PF06143.6 KFP03768.1 - 0.02 14.2 0.5 0.034 13.5 0.4 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF912 PF06024.7 KFP03768.1 - 0.079 13.0 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Syndecan PF01034.15 KFP03768.1 - 0.11 12.2 0.6 0.22 11.2 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain SIT PF15330.1 KFP03768.1 - 0.34 11.0 0.6 17 5.5 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Rifin_STEVOR PF02009.11 KFP03768.1 - 0.74 9.4 0.8 1.3 8.5 0.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF836 PF05768.9 KFP03771.1 - 1.6e-12 47.5 0.1 1.8e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KFP03771.1 - 0.027 14.4 0.1 0.04 13.9 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin RINGv PF12906.2 KFP03772.1 - 8.4e-15 54.5 10.3 8.4e-15 54.5 7.1 1.9 2 0 0 2 2 2 1 RING-variant domain zf-C3HC4 PF00097.20 KFP03772.1 - 0.075 12.7 5.9 0.35 10.5 4.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vpu PF00558.14 KFP03772.1 - 0.095 12.2 0.4 0.16 11.5 0.3 1.3 1 0 0 1 1 1 0 Vpu protein Baculo_IE-1 PF05290.6 KFP03772.1 - 0.11 12.2 1.8 0.2 11.3 1.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-AD PF07776.10 KFP03772.1 - 0.73 9.8 6.0 1.7 8.7 4.1 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-RING_2 PF13639.1 KFP03772.1 - 2.8 7.8 15.8 0.37 10.6 6.9 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 KFP03772.1 - 3 7.9 8.2 8.7 6.4 5.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KFP03772.1 - 3.5 7.4 7.8 8.7 6.1 5.4 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 KFP03772.1 - 4.7 7.2 10.4 0.68 9.9 3.1 2.5 2 1 1 3 3 3 0 FANCL C-terminal domain zf-RING-like PF08746.6 KFP03772.1 - 5.6 7.0 7.3 12 6.0 5.1 1.6 1 0 0 1 1 1 0 RING-like domain RNA_GG_bind PF10258.4 KFP03773.1 - 5.2e-31 106.1 3.5 7.7e-31 105.6 0.4 2.6 3 0 0 3 3 3 1 PHAX RNA-binding domain FoP_duplication PF13865.1 KFP03773.1 - 0.021 15.2 3.0 0.021 15.2 2.1 2.1 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Cmyb_C PF09316.5 KFP03773.1 - 0.028 14.0 0.2 0.076 12.6 0.1 1.7 1 0 0 1 1 1 0 C-myb, C-terminal zf-C2H2 PF00096.21 KFP03774.1 - 3.9e-16 58.3 21.3 1.4e-05 25.0 2.1 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03774.1 - 7.3e-13 47.8 18.5 0.00028 20.9 1.8 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP03774.1 - 3.4e-12 45.9 25.1 8.2e-07 29.0 2.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 KFP03774.1 - 0.015 15.4 4.9 0.75 10.0 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 KFP03774.1 - 0.12 11.8 3.2 0.29 10.6 2.2 1.6 1 0 0 1 1 1 0 InsA N-terminal domain zf-C2H2_jaz PF12171.3 KFP03774.1 - 0.19 11.9 5.3 1.5 9.0 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KFP03774.1 - 1.1 9.6 7.1 0.65 10.4 0.8 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.10 KFP03774.1 - 2.8 7.7 12.4 11 5.8 2.2 3.1 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 KFP03774.1 - 8.4 6.4 8.9 1.3 9.0 0.5 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger XPC-binding PF09280.6 KFP03775.1 - 1.5e-25 88.3 18.2 2.6e-25 87.6 12.6 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KFP03775.1 - 1.8e-22 78.5 0.9 1.1e-12 47.3 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KFP03775.1 - 2.4e-15 55.6 0.0 4.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.5 KFP03775.1 - 0.00034 20.1 0.0 0.0088 15.6 0.0 2.3 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 KFP03775.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFP03775.1 - 0.016 15.3 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rap1_C PF11626.3 KFP03775.1 - 0.017 15.0 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rad60-SLD PF11976.3 KFP03775.1 - 0.048 13.3 0.1 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 KFP03775.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain DUF3138 PF11336.3 KFP03775.1 - 0.87 7.6 5.5 0.47 8.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) zf-H2C2_5 PF13909.1 KFP03776.1 - 9.1e-54 176.6 268.7 0.00014 21.8 0.6 32.5 32 0 0 32 32 32 27 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KFP03776.1 - 0.00029 20.9 0.7 0.0017 18.5 0.1 31.8 34 0 0 34 34 34 17 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP03776.1 - 0.0027 17.9 6.7 0.0027 17.9 4.7 29.6 34 0 0 34 34 34 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03776.1 - 0.012 15.9 0.2 0.012 15.9 0.1 30.5 33 0 0 33 33 33 0 Zinc finger, C2H2 type TRIC PF05197.8 KFP03778.1 - 1.4e-90 301.9 5.5 1.7e-90 301.7 3.8 1.0 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.8 KFP03778.1 - 0.0073 15.9 5.6 0.35 10.5 0.0 2.7 2 1 0 2 2 2 2 UPF0126 domain HLH PF00010.21 KFP03779.1 - 1.5e-17 62.9 0.6 2.2e-17 62.4 0.4 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PMBR PF09373.5 KFP03779.1 - 0.067 13.1 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Pseudomurein-binding repeat RF-1 PF00472.15 KFP03779.1 - 0.097 12.4 0.2 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 RF-1 domain LicD PF04991.8 KFP03780.1 - 2.4e-13 50.6 2.5 5.3e-12 46.2 0.5 3.1 2 1 0 2 2 2 1 LicD family SPRY PF00622.23 KFP03781.1 - 2.6e-16 59.8 0.2 5.5e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.16 KFP03781.1 - 1.9e-06 27.8 0.0 5.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain LOH1CR12 PF10158.4 KFP03781.1 - 0.058 13.1 1.1 0.11 12.2 0.7 1.5 1 0 0 1 1 1 0 Tumour suppressor protein Sec20 PF03908.8 KFP03781.1 - 0.2 11.3 2.2 1.4 8.6 0.4 2.6 1 1 1 2 2 2 0 Sec20 Choline_transpo PF04515.7 KFP03782.1 - 7.5e-101 337.2 35.4 7.5e-101 337.2 24.5 1.9 2 0 0 2 2 2 1 Plasma-membrane choline transporter AF-4 PF05110.8 KFP03783.1 - 6.9e-90 302.4 23.4 1.1e-60 205.8 11.5 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein Ins145_P3_rec PF08709.6 KFP03784.1 - 1.7e-16 59.9 0.2 1.8e-16 59.8 0.2 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor 7tm_1 PF00001.16 KFP03785.1 - 2.3e-20 72.8 3.9 3e-20 72.4 2.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP03785.1 - 3.8e-05 22.9 1.5 4.8e-05 22.6 1.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFP03785.1 - 4.3e-05 23.3 0.3 4.3e-05 23.3 0.2 2.1 2 1 0 2 2 2 1 Olfactory receptor UPF0016 PF01169.14 KFP03785.1 - 0.1 12.7 0.2 0.1 12.7 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 Ribosomal_L18e PF00828.14 KFP03786.1 - 1.3e-13 51.4 0.7 5.7e-13 49.3 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_2 PF02230.11 KFP03787.1 - 2.8e-72 242.6 0.0 3.2e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFP03787.1 - 2.6e-10 40.2 0.0 3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP03787.1 - 2.9e-07 30.6 0.0 7.3e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFP03787.1 - 1.6e-06 27.8 0.0 1.5e-05 24.6 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFP03787.1 - 0.00013 21.5 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 KFP03787.1 - 0.00043 20.0 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.16 KFP03787.1 - 0.0017 17.5 0.0 0.79 8.8 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family DUF2974 PF11187.3 KFP03787.1 - 0.0021 17.4 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.13 KFP03787.1 - 0.025 13.8 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.20 KFP03787.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.8 KFP03787.1 - 0.038 13.4 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 KFP03787.1 - 0.054 12.9 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 KFP03787.1 - 0.17 10.3 0.0 0.25 9.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TFIIS_M PF07500.9 KFP03788.1 - 1.5e-41 141.0 3.1 1.5e-41 141.0 2.1 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KFP03788.1 - 2e-19 68.9 8.2 4.4e-19 67.8 5.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KFP03788.1 - 4.9e-11 41.9 0.6 1.5e-10 40.4 0.4 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TF_Zn_Ribbon PF08271.7 KFP03788.1 - 0.3 10.4 5.4 0.47 9.8 2.5 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Baculo_LEF5_C PF11792.3 KFP03788.1 - 0.41 10.0 2.7 1.4 8.3 1.8 1.9 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain tRNA_synt_1c_R2 PF04557.10 KFP03788.1 - 0.5 11.1 7.1 0.11 13.2 1.2 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF4355 PF14265.1 KFP03788.1 - 1.7 8.6 15.5 0.22 11.4 1.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) RGS PF00615.14 KFP03789.1 - 1.4e-34 118.7 1.6 1.8e-34 118.3 1.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain V-ATPase_H_N PF03224.9 KFP03790.1 - 1.9e-105 352.4 6.2 2.9e-105 351.8 4.3 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KFP03790.1 - 4.8e-30 103.9 4.2 5.5e-30 103.7 0.0 2.9 3 1 0 3 3 3 1 V-ATPase subunit H Arm PF00514.18 KFP03790.1 - 1.4e-06 27.8 0.3 0.0026 17.5 0.0 4.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF3826 PF12875.2 KFP03790.1 - 0.0028 17.3 0.7 0.0066 16.1 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) UCH PF00443.24 KFP03790.1 - 0.0039 16.3 1.8 0.0041 16.2 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase YlbD_coat PF14071.1 KFP03790.1 - 0.0072 16.3 1.9 0.0072 16.3 1.3 2.1 2 0 0 2 2 2 1 Putative coat protein DUF2326 PF10088.4 KFP03790.1 - 0.028 14.0 0.3 0.028 14.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2326) Muted PF14942.1 KFP03790.1 - 0.63 9.9 7.8 0.11 12.3 1.2 2.4 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein 7tm_1 PF00001.16 KFP03791.1 - 2.7e-63 213.5 22.1 3.2e-63 213.2 15.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP03791.1 - 6.3e-09 35.3 16.1 8.3e-09 34.9 11.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFP03791.1 - 3.3e-07 29.7 21.8 4e-07 29.4 15.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Fumarate_red_D PF02313.12 KFP03791.1 - 0.011 15.5 1.6 0.032 14.1 1.1 1.7 1 0 0 1 1 1 0 Fumarate reductase subunit D Herpes_US9 PF06072.6 KFP03791.1 - 0.1 12.4 0.2 0.1 12.4 0.1 2.7 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 7TM_GPCR_Str PF10326.4 KFP03791.1 - 0.12 11.5 15.0 93 1.9 10.4 2.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF3810 PF12725.2 KFP03791.1 - 1.6 7.5 4.7 2.8 6.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) E1-E2_ATPase PF00122.15 KFP03791.1 - 4.2 6.3 7.3 2.2 7.2 0.3 2.2 1 1 1 2 2 2 0 E1-E2 ATPase ATG11 PF10377.4 KFP03792.1 - 2.2e-23 82.5 0.0 2.2e-23 82.5 0.0 4.5 5 1 0 5 5 5 1 Autophagy-related protein 11 MYT1 PF08474.6 KFP03793.1 - 2.2e-96 322.3 8.6 5.3e-96 321.0 6.0 1.7 1 0 0 1 1 1 1 Myelin transcription factor 1 zf-C2HC PF01530.13 KFP03793.1 - 1.8e-91 299.4 66.7 4.5e-17 61.4 3.3 6.5 6 0 0 6 6 6 6 Zinc finger, C2HC type DUF1664 PF07889.7 KFP03793.1 - 0.0023 17.7 0.2 0.0068 16.1 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Sina PF03145.11 KFP03793.1 - 0.11 12.1 3.0 0.82 9.3 0.5 2.8 2 0 0 2 2 2 0 Seven in absentia protein family IBR PF01485.16 KFP03793.1 - 0.27 11.1 14.8 42 4.1 0.0 6.1 4 2 0 4 4 4 0 IBR domain DUF342 PF03961.8 KFP03793.1 - 0.36 9.2 6.8 0.18 10.2 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) ADIP PF11559.3 KFP03793.1 - 1.3 8.9 12.7 0.033 14.0 3.2 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.7 KFP03793.1 - 4.7 7.4 13.0 0.29 11.3 3.0 3.5 3 1 1 4 4 4 0 Centromere protein H (CENP-H) PCMT PF01135.14 KFP03794.1 - 1.2e-28 100.1 0.0 1.6e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.11 KFP03794.1 - 1.7e-06 27.7 3.1 0.003 17.3 0.7 2.7 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.8 KFP03794.1 - 0.00011 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 KFP03794.1 - 0.00027 21.4 0.0 0.00054 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP03794.1 - 0.00034 20.2 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KFP03794.1 - 0.004 16.6 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.7 KFP03794.1 - 0.031 14.7 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PDZ PF00595.19 KFP03796.1 - 2.7e-17 62.6 0.6 4.7e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PH PF00169.24 KFP03796.1 - 3.2e-05 24.0 0.6 0.016 15.3 0.2 2.7 2 1 0 2 2 2 2 PH domain PDZ_2 PF13180.1 KFP03796.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Marek_SORF3 PF07153.6 KFP03796.1 - 0.031 12.9 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Tricorn_PDZ PF14685.1 KFP03796.1 - 0.096 12.4 0.1 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain PPDFL PF15060.1 KFP03797.1 - 0.00078 19.4 0.2 0.11 12.5 0.0 2.1 2 0 0 2 2 2 2 Differentiation and proliferation regulator zf-H2C2_2 PF13465.1 KFP03798.1 - 9.7e-26 88.7 28.6 5.6e-09 35.8 0.2 5.7 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03798.1 - 7.5e-25 85.7 43.3 4.2e-06 26.7 0.3 5.6 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03798.1 - 1.5e-17 62.5 35.9 0.00039 20.5 1.4 6.1 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP03798.1 - 1.1e-14 54.1 28.1 0.00023 21.2 0.2 6.2 5 1 1 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP03798.1 - 2.6e-13 49.3 31.2 0.00034 20.3 3.1 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-Di19 PF05605.7 KFP03798.1 - 2.5e-07 30.7 18.5 0.0061 16.6 2.7 3.7 3 1 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFP03798.1 - 6.7e-07 29.3 27.5 0.0055 16.8 0.3 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-BED PF02892.10 KFP03798.1 - 5.5e-06 26.0 26.6 0.17 11.6 1.4 5.5 3 1 2 5 5 5 4 BED zinc finger zf-C2HC_2 PF13913.1 KFP03798.1 - 0.00023 20.7 17.2 0.49 10.1 0.3 5.5 5 0 0 5 5 5 3 zinc-finger of a C2HC-type Elf1 PF05129.8 KFP03798.1 - 0.00029 20.4 17.0 0.023 14.3 0.5 3.2 2 1 1 3 3 3 2 Transcription elongation factor Elf1 like Rpr2 PF04032.11 KFP03798.1 - 0.0027 17.5 13.0 0.057 13.3 0.4 2.4 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_2 PF12756.2 KFP03798.1 - 0.0035 17.4 22.2 1.6 8.8 0.3 5.1 1 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 KFP03798.1 - 0.14 12.1 26.1 0.79 9.7 1.6 4.8 4 1 0 4 4 4 0 Zinc ribbon domain PyrI_C PF02748.10 KFP03798.1 - 0.16 11.4 18.2 2.6 7.5 0.9 4.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Trm112p PF03966.11 KFP03798.1 - 0.22 11.9 2.2 10 6.5 0.4 3.6 3 1 0 3 3 3 0 Trm112p-like protein Zn_Tnp_IS1595 PF12760.2 KFP03798.1 - 1.1 9.0 26.8 0.063 13.1 4.2 4.0 2 2 2 4 4 4 0 Transposase zinc-ribbon domain zf-CHCC PF10276.4 KFP03798.1 - 2.1 8.2 13.2 2.7 7.8 1.4 4.2 4 0 0 4 4 4 0 Zinc-finger domain zf-CHY PF05495.7 KFP03798.1 - 2.7 8.2 26.7 2.1 8.5 5.0 2.5 2 1 0 2 2 2 0 CHY zinc finger zf-AN1 PF01428.11 KFP03798.1 - 3.8 7.4 24.7 11 6.0 0.1 5.3 5 0 0 5 5 5 0 AN1-like Zinc finger zinc_ribbon_5 PF13719.1 KFP03798.1 - 5.9 6.5 18.7 2.7 7.6 0.2 4.8 5 0 0 5 5 5 0 zinc-ribbon domain zf-HYPF PF07503.7 KFP03798.1 - 9.6 5.7 14.5 2.7 7.4 0.6 3.4 3 1 0 3 3 3 0 HypF finger zf-met2 PF12907.2 KFP03798.1 - 9.6 6.2 15.7 3.3 7.7 0.2 4.9 5 0 0 5 5 5 0 Zinc-binding Voltage_CLC PF00654.15 KFP03799.1 - 6.5e-22 78.0 8.7 7.1e-22 77.9 6.0 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel UQ_con PF00179.21 KFP03800.1 - 1e-18 67.0 0.0 1.1e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFP03800.1 - 0.0035 17.2 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain MCM PF00493.18 KFP03801.1 - 1.3e-134 448.2 0.2 2.3e-134 447.3 0.0 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KFP03801.1 - 4.1e-26 91.8 0.4 1.4e-25 90.1 0.3 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFP03801.1 - 4.1e-08 32.6 0.1 1.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFP03801.1 - 1.2e-07 31.5 0.1 7.7e-07 28.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFP03801.1 - 3.6e-05 23.3 0.0 6.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFP03801.1 - 0.0097 15.3 0.0 3.6 7.0 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain HypA PF01155.14 KFP03801.1 - 0.015 14.9 0.8 0.038 13.6 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family AAA PF00004.24 KFP03801.1 - 0.03 14.5 0.0 0.094 12.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Elf1 PF05129.8 KFP03801.1 - 0.075 12.7 0.5 0.71 9.6 0.3 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like NUC194 PF08163.7 KFP03802.1 - 2.4e-184 612.7 0.9 4.3e-184 611.9 0.6 1.4 1 0 0 1 1 1 1 NUC194 domain FAT PF02259.18 KFP03802.1 - 2.3e-69 234.0 12.9 2.3e-69 234.0 6.7 2.6 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KFP03802.1 - 1.1e-58 198.4 1.5 1.7e-58 197.8 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFP03802.1 - 6.3e-11 41.5 0.1 1.5e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 KFP03802.1 - 0.11 12.4 6.2 3.1 7.9 1.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFP03802.1 - 0.15 11.9 1.5 29 4.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFP03802.1 - 0.15 11.7 3.7 4.1 7.1 1.2 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP03802.1 - 9.7 6.2 9.8 5.4 7.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4503 PF14951.1 KFP03803.1 - 1.9e-152 506.9 7.8 3e-152 506.3 5.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) DUF4502 PF14950.1 KFP03803.1 - 1.3e-46 159.3 0.2 2e-46 158.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) DUF4502 PF14950.1 KFP03804.1 - 1.4e-35 123.0 17.6 1.7e-35 122.8 12.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) CDP-OH_P_transf PF01066.16 KFP03805.1 - 2e-10 40.8 25.1 4.6e-09 36.5 17.3 3.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase EB1 PF03271.12 KFP03806.1 - 3.7e-15 55.6 0.1 9.5e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KFP03806.1 - 2e-11 43.8 0.4 4.5e-11 42.7 0.3 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP03806.1 - 0.0029 17.2 0.1 0.0078 15.8 0.1 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Suppressor_APC PF11414.3 KFP03806.1 - 0.018 14.8 0.5 0.033 13.9 0.3 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein EF-hand_2 PF09068.6 KFP03807.1 - 1.8e-40 137.9 0.9 1.1e-39 135.4 0.5 2.2 2 0 0 2 2 2 1 EF hand EF-hand_3 PF09069.6 KFP03807.1 - 3.9e-35 119.7 0.1 1.3e-34 118.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand ZZ PF00569.12 KFP03807.1 - 5.3e-11 41.8 10.3 1.2e-10 40.7 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Seryl_tRNA_N PF02403.17 KFP03807.1 - 0.015 15.2 7.7 0.059 13.3 5.4 2.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tnp_zf-ribbon_2 PF13842.1 KFP03807.1 - 0.15 12.5 7.6 0.34 11.3 5.3 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF342 PF03961.8 KFP03807.1 - 0.45 8.8 4.5 0.81 8.0 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFP03807.1 - 2.3 7.1 12.2 5.9 5.8 8.4 1.7 1 0 0 1 1 1 0 Autophagy protein Apg6 BEN PF10523.4 KFP03808.1 - 0.07 13.1 0.2 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 BEN domain zf-H2C2 PF09337.5 KFP03808.1 - 0.078 12.4 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger DUF3432 PF11914.3 KFP03809.1 - 1.1e-07 31.8 74.3 0.51 10.4 8.4 7.9 1 1 5 6 6 6 6 Domain of unknown function (DUF3432) Cornifin PF02389.10 KFP03809.1 - 9.1 5.9 24.2 12 5.6 7.0 2.2 1 1 1 2 2 2 0 Cornifin (SPRR) family ASXH PF13919.1 KFP03810.1 - 6.2e-48 162.1 3.3 9.2e-48 161.5 0.7 2.6 2 0 0 2 2 2 1 Asx homology domain PHD_3 PF13922.1 KFP03810.1 - 1.4e-24 86.0 8.7 1.4e-24 86.0 6.0 4.0 2 0 0 2 2 2 1 PHD domain of transcriptional enhancer, Asx HARE-HTH PF05066.8 KFP03810.1 - 5.1e-13 49.1 0.0 1.2e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain DUF2968 PF11180.3 KFP03812.1 - 0.37 10.1 9.8 0.5 9.7 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1664 PF07889.7 KFP03812.1 - 0.43 10.3 3.2 0.74 9.6 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HTH_37 PF13744.1 KFP03812.1 - 0.58 10.0 5.0 0.067 13.0 0.4 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain LRS4 PF10422.4 KFP03812.1 - 0.62 9.3 5.7 0.94 8.7 3.9 1.3 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4140 PF13600.1 KFP03812.1 - 7 7.1 7.2 22 5.5 0.4 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RVT_1 PF00078.22 KFP03814.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ras PF00071.17 KFP03816.1 - 3.6e-45 153.2 0.1 4.5e-45 152.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP03816.1 - 1.1e-11 45.2 0.1 1.8e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP03816.1 - 1.5e-08 34.1 0.2 1.7e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP03816.1 - 2.8e-05 23.6 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP03816.1 - 0.0048 16.0 0.1 0.0074 15.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region CABIT PF12736.2 KFP03817.1 - 8e-52 175.7 0.4 1.1e-51 175.2 0.3 1.2 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, SAM_1 PF00536.25 KFP03817.1 - 0.0019 18.3 0.1 0.0035 17.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Astacin PF01400.19 KFP03818.1 - 2.3e-70 235.8 0.2 4.2e-70 235.0 0.1 1.5 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) MAM PF00629.18 KFP03818.1 - 3e-40 137.6 0.1 5.7e-40 136.7 0.1 1.5 1 0 0 1 1 1 1 MAM domain MATH PF00917.21 KFP03818.1 - 3.7e-26 91.6 0.0 8.2e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 MATH domain EGF PF00008.22 KFP03818.1 - 1.7e-05 24.7 2.9 4.8e-05 23.2 2.0 1.9 1 0 0 1 1 1 1 EGF-like domain DAG1 PF05454.6 KFP03818.1 - 0.018 14.2 0.1 0.026 13.7 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EGF_2 PF07974.8 KFP03818.1 - 0.087 13.0 5.3 0.24 11.6 3.7 1.8 1 0 0 1 1 1 0 EGF-like domain zf-Di19 PF05605.7 KFP03819.1 - 6e-16 58.3 8.0 1.3e-15 57.2 1.0 2.9 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 KFP03819.1 - 0.013 15.1 1.3 0.013 15.1 0.9 3.5 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KFP03819.1 - 0.062 12.9 1.3 0.062 12.9 0.9 4.1 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.7 KFP03819.1 - 0.22 11.3 13.4 0.3 10.9 3.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1644) GAGA PF09237.6 KFP03819.1 - 0.55 9.8 13.5 0.12 11.9 1.8 3.5 2 1 1 3 3 3 0 GAGA factor zf-Di19 PF05605.7 KFP03820.1 - 0.0019 18.3 0.4 0.0019 18.3 0.3 3.8 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KFP03820.1 - 0.032 14.4 0.6 0.032 14.4 0.4 4.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-Sec23_Sec24 PF04810.10 KFP03820.1 - 0.19 11.2 0.0 0.19 11.2 0.0 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Rubredoxin PF00301.15 KFP03820.1 - 2.4 8.1 9.4 1.1 9.1 0.5 2.5 2 0 0 2 2 2 0 Rubredoxin TRAPPC-Trs85 PF12739.2 KFP03821.1 - 2.4e-97 326.2 9.2 1.5e-75 254.4 4.8 2.2 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.1 KFP03821.1 - 0.0088 15.2 3.8 0.02 14.0 0.3 2.5 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP Glyco_transf_7N PF13733.1 KFP03822.1 - 8.3e-43 145.0 0.0 1.2e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFP03822.1 - 1.7e-27 94.6 0.9 3e-27 93.8 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP03822.1 - 6.6e-08 31.9 0.3 0.00059 19.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Anp1 PF03452.9 KFP03822.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.4 1 1 0 1 1 1 0 Anp1 Transthyretin PF00576.16 KFP03823.1 - 7.5e-22 77.3 0.1 8.8e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Transthyretin PF00576.16 KFP03824.1 - 1.1e-38 131.5 0.1 1.3e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Cadherin PF00028.12 KFP03825.1 - 3.8e-58 193.7 4.4 4e-18 65.4 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFP03825.1 - 1.9e-07 31.2 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFP03825.1 - 5.2e-05 22.7 0.0 0.5 9.9 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like BACON PF13004.2 KFP03825.1 - 0.049 13.8 2.5 0.44 10.7 1.0 2.9 2 0 0 2 2 2 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal DUF2963 PF11178.3 KFP03825.1 - 0.28 10.6 2.0 0.73 9.3 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) Cadherin PF00028.12 KFP03826.1 - 4.6e-52 174.2 0.1 1.5e-16 60.4 0.0 4.4 4 0 0 4 4 4 4 Cadherin domain Cadherin_C PF01049.12 KFP03826.1 - 8.4e-11 42.1 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region DUF3990 PF13151.1 KFP03826.1 - 0.15 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) Cadherin_2 PF08266.7 KFP03826.1 - 0.2 11.2 0.0 8.3 6.0 0.0 2.8 3 0 0 3 3 3 0 Cadherin-like Cadherin PF00028.12 KFP03827.1 - 1.1e-64 214.6 2.6 9.2e-15 54.6 0.0 6.3 7 0 0 7 7 7 5 Cadherin domain Cadherin_C PF01049.12 KFP03827.1 - 1.3e-18 67.4 0.7 1.2e-17 64.2 0.4 2.5 1 1 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 KFP03827.1 - 1.9e-15 56.4 1.8 2.2e-14 52.9 0.2 3.4 4 0 0 4 4 4 1 Cadherin prodomain like Cadherin PF00028.12 KFP03828.1 - 4.3e-91 299.3 2.5 8.9e-23 80.3 0.1 5.8 6 0 0 6 6 6 5 Cadherin domain Cadherin_C PF01049.12 KFP03828.1 - 7.8e-55 185.0 1.5 1.4e-54 184.1 1.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_pro PF08758.6 KFP03828.1 - 2.7e-28 97.5 0.2 1.1e-27 95.5 0.1 2.1 2 0 0 2 2 2 1 Cadherin prodomain like He_PIG PF05345.7 KFP03828.1 - 1.7e-06 27.9 3.1 0.7 9.9 0.3 5.8 5 0 0 5 5 5 2 Putative Ig domain Cadherin_2 PF08266.7 KFP03828.1 - 0.0053 16.3 0.0 4.9 6.7 0.0 3.3 3 0 0 3 3 3 1 Cadherin-like DUF2207 PF09972.4 KFP03828.1 - 0.046 12.3 0.0 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Prok-E2_A PF14457.1 KFP03828.1 - 0.082 12.3 0.1 0.35 10.3 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family A SIT PF15330.1 KFP03828.1 - 0.19 11.9 0.1 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Rifin_STEVOR PF02009.11 KFP03828.1 - 0.4 10.2 1.5 0.63 9.6 1.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Big_3_4 PF13754.1 KFP03828.1 - 0.47 10.8 13.2 0.5 10.7 0.3 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Sulfotransfer_2 PF03567.9 KFP03829.1 - 1.9e-61 207.9 1.6 2.4e-61 207.6 1.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF4368 PF14287.1 KFP03829.1 - 0.059 13.1 0.7 2.1 8.1 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4368) MIP PF00230.15 KFP03830.1 - 7.2e-73 244.8 14.0 9e-73 244.4 9.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein BTB_2 PF02214.17 KFP03831.1 - 2.2e-17 63.0 0.0 3.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF4 PF05236.9 KFP03832.1 - 1.8e-57 194.6 8.9 3e-57 193.9 6.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAFH PF07531.9 KFP03832.1 - 5.5e-37 125.3 1.4 3e-36 122.9 1.0 2.4 1 0 0 1 1 1 1 NHR1 homology to TAF SSXT PF05030.7 KFP03833.1 - 6.4e-29 99.3 2.6 1e-28 98.6 1.8 1.3 1 0 0 1 1 1 1 SSXT protein (N-terminal region) zf-C2H2 PF00096.21 KFP03834.1 - 9.4e-53 173.4 223.9 0.00069 19.8 3.1 30.7 31 0 0 31 31 31 26 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03834.1 - 6.9e-50 163.7 203.5 0.0022 18.1 0.5 30.2 31 0 0 31 31 31 24 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP03834.1 - 4.1e-35 118.3 184.7 3.9e-06 26.8 0.6 30.1 33 0 0 33 33 33 19 Zinc-finger double domain zf-Di19 PF05605.7 KFP03834.1 - 2.7e-25 88.2 167.8 8e-05 22.6 2.3 19.7 16 3 4 20 20 20 12 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFP03834.1 - 2.2e-20 71.8 163.3 3.7e-05 23.4 0.3 25.1 27 1 1 28 28 28 14 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP03834.1 - 1.1e-15 57.2 154.7 0.00091 19.3 0.4 24.5 25 1 1 26 26 26 12 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP03834.1 - 7.3e-06 26.0 167.1 0.082 13.0 0.4 24.5 8 6 14 23 23 23 13 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFP03834.1 - 0.00053 20.0 6.4 0.0074 16.4 0.8 22.4 25 0 0 25 25 25 9 Zinc-finger of C2H2 type 7tm_1 PF00001.16 KFP03835.1 - 3.7e-62 209.7 8.5 4.3e-62 209.5 5.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP03835.1 - 4e-07 29.4 10.7 0.00014 21.0 3.7 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP03835.1 - 8.4e-05 21.7 9.5 8.4e-05 21.7 6.6 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx UPF0029 PF01205.14 KFP03836.1 - 2.9e-33 113.8 0.0 4.3e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KFP03836.1 - 7.7e-18 64.4 0.4 7.7e-18 64.4 0.3 1.7 2 1 0 2 2 2 1 RWD domain Oxysterol_BP PF01237.13 KFP03837.1 - 1.4e-146 487.5 0.8 1.9e-146 487.1 0.6 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank PF00023.25 KFP03837.1 - 6.2e-30 101.5 4.9 6.2e-11 41.5 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFP03837.1 - 1.3e-29 101.5 3.8 1.8e-13 50.2 0.2 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFP03837.1 - 1.6e-28 98.8 3.0 7.6e-17 61.4 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP03837.1 - 6.2e-23 80.7 2.7 5.3e-06 26.7 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP03837.1 - 1.3e-22 77.5 2.4 1.3e-06 28.0 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 KFP03837.1 - 0.083 13.0 3.9 0.15 12.2 0.1 2.9 2 1 0 2 2 2 0 PH domain PH_11 PF15413.1 KFP03837.1 - 2.7 8.2 7.8 0.54 10.5 0.1 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain DUF3808 PF10300.4 KFP03838.1 - 3e-131 438.2 6.7 3.6e-131 437.9 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Cohesin_load PF10345.4 KFP03838.1 - 6.9e-07 27.8 4.8 9.4e-07 27.4 0.1 2.4 2 1 1 3 3 3 1 Cohesin loading factor TPR_2 PF07719.12 KFP03838.1 - 3.3e-06 26.5 2.0 0.078 12.9 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP03838.1 - 2.7e-05 23.5 1.1 0.058 13.0 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFP03838.1 - 4.8e-05 23.2 0.1 0.8 9.6 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP03838.1 - 0.0041 17.4 0.4 28 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFP03838.1 - 0.011 15.4 0.3 0.17 11.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2724 PF10893.3 KFP03838.1 - 0.068 13.0 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Laminin_EGF PF00053.19 KFP03839.1 - 1.7e-97 319.1 310.7 5.1e-10 39.1 8.5 17.1 15 2 2 17 17 17 15 Laminin EGF-like (Domains III and V) Laminin_G_2 PF02210.19 KFP03839.1 - 9.7e-83 274.5 0.2 2.9e-27 95.2 0.0 6.3 5 1 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.18 KFP03839.1 - 6.3e-63 210.6 0.6 4.1e-21 75.3 0.1 6.1 5 1 1 6 6 6 4 Laminin G domain Laminin_N PF00055.12 KFP03839.1 - 1.7e-57 194.1 0.0 5.2e-57 192.5 0.0 1.9 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_I PF06008.9 KFP03839.1 - 3.1e-48 164.3 32.4 3.1e-48 164.3 22.4 3.6 1 1 2 3 3 3 1 Laminin Domain I Laminin_II PF06009.7 KFP03839.1 - 2.7e-35 121.1 0.6 2.7e-35 121.1 0.4 5.6 3 2 2 5 5 5 1 Laminin Domain II Laminin_B PF00052.13 KFP03839.1 - 1.8e-19 69.6 0.0 4.9e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.1 KFP03839.1 - 1e-13 51.8 0.0 2.4e-05 24.6 0.0 3.9 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Myosin_tail_1 PF01576.14 KFP03839.1 - 7.1 4.2 49.5 4 5.0 8.7 2.6 1 1 1 2 2 2 0 Myosin tail Ank_2 PF12796.2 KFP03840.1 - 1.5e-66 220.7 5.5 1.4e-18 67.0 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFP03840.1 - 1.6e-53 175.9 8.0 2.9e-08 33.1 0.0 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KFP03840.1 - 8.7e-42 140.7 10.1 4.9e-11 42.8 0.1 6.1 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP03840.1 - 1.6e-34 114.4 2.7 0.0017 18.4 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KFP03840.1 - 6.7e-31 105.6 11.7 5.5e-10 39.1 0.1 8.1 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFP03840.1 - 0.042 13.3 0.1 1.7 8.1 0.0 3.1 2 1 2 4 4 4 0 Shigella flexneri OspC protein Patched PF02460.13 KFP03841.1 - 1.3e-82 278.0 21.5 1.5e-81 274.5 15.3 2.1 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.3 KFP03841.1 - 3.2e-55 185.7 5.9 3.2e-55 185.7 4.1 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KFP03841.1 - 2.1e-05 23.4 4.2 2.1e-05 23.4 2.9 2.3 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.14 KFP03841.1 - 0.00047 17.7 7.5 0.00047 17.7 5.2 2.1 2 1 0 2 2 2 1 AcrB/AcrD/AcrF family Mic1 PF07035.7 KFP03842.1 - 2.5e-74 248.1 0.4 2.5e-74 248.1 0.3 1.6 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like RIO1 PF01163.17 KFP03843.1 - 3e-75 251.7 0.3 3e-75 251.7 0.2 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KFP03843.1 - 0.00082 18.4 0.1 0.0033 16.5 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP03843.1 - 0.0022 17.8 0.2 0.057 13.1 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP03843.1 - 0.043 13.3 1.7 0.072 12.6 0.3 2.0 2 1 0 2 2 2 0 Choline/ethanolamine kinase DUF457 PF04307.9 KFP03844.1 - 0.29 10.4 6.2 0.48 9.7 3.9 2.0 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) EamA PF00892.15 KFP03844.1 - 2.8 8.0 15.2 0.19 11.7 4.7 2.3 2 1 0 2 2 2 0 EamA-like transporter family Cyclin_N PF00134.18 KFP03845.1 - 3.9e-08 32.8 0.2 5.7e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain CtIP_N PF10482.4 KFP03846.1 - 4.9e-55 184.4 20.3 2.2e-54 182.3 14.1 2.2 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain SAE2 PF08573.5 KFP03846.1 - 2.5e-09 37.7 4.4 2.5e-09 37.7 3.1 5.2 3 2 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Ank PF00023.25 KFP03848.1 - 2.1e-55 181.8 16.6 2e-08 33.6 0.0 9.7 10 1 0 10 10 10 8 Ankyrin repeat Ank_2 PF12796.2 KFP03848.1 - 9.9e-55 182.8 16.2 1.2e-16 60.7 0.0 5.8 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP03848.1 - 5.6e-48 159.8 16.2 2.8e-12 46.4 0.0 7.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP03848.1 - 7.7e-41 137.7 14.6 1.4e-11 44.5 0.1 7.6 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP03848.1 - 4.7e-32 106.8 17.9 0.00028 20.8 0.0 10.1 11 0 0 11 11 11 6 Ankyrin repeat MIB_HERC2 PF06701.8 KFP03848.1 - 1.1e-28 99.0 6.6 3e-28 97.6 3.2 2.9 2 0 0 2 2 2 1 Mib_herc2 zf-C3HC4_3 PF13920.1 KFP03848.1 - 4.5e-28 96.6 59.9 4.2e-11 42.3 9.5 4.7 4 1 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.12 KFP03848.1 - 4.7e-11 42.0 8.2 4.7e-11 42.0 5.7 3.6 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-C3HC4_2 PF13923.1 KFP03848.1 - 7.4e-05 22.6 62.1 0.0019 18.2 7.0 5.0 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 KFP03849.1 - 1.6e-12 47.7 0.0 2.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP03849.1 - 1.1e-05 25.1 0.0 2.9e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP03849.1 - 2.2e-05 24.1 0.0 5.7e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KFP03849.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Acetyltransf_13 PF13880.1 KFP03850.1 - 8.4e-32 108.7 0.0 1.7e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KFP03850.1 - 6.5e-17 60.8 0.0 1.3e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Pkinase PF00069.20 KFP03852.1 - 6.4e-61 205.7 0.0 6.4e-61 205.7 0.0 3.6 5 0 0 5 5 5 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03852.1 - 4.3e-30 104.6 0.1 2e-29 102.4 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Rho_Binding PF08912.6 KFP03852.1 - 1.3e-23 83.0 12.5 1.3e-23 83.0 8.6 11.7 6 3 3 11 11 11 1 Rho Binding HR1 PF02185.11 KFP03852.1 - 3.1e-11 42.8 13.6 3.1e-11 42.8 9.4 10.5 7 3 3 10 10 10 1 Hr1 repeat PH PF00169.24 KFP03852.1 - 1.6e-06 28.2 0.1 1.6e-06 28.2 0.0 3.7 3 2 0 3 3 3 1 PH domain Pkinase_C PF00433.19 KFP03852.1 - 3.7e-05 24.1 2.3 0.00011 22.6 1.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Myosin_tail_1 PF01576.14 KFP03852.1 - 0.0001 20.2 170.3 0.00063 17.6 24.9 4.0 1 1 2 3 3 3 2 Myosin tail C1_1 PF00130.17 KFP03852.1 - 0.00048 19.7 5.9 0.0011 18.6 4.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 KFP03852.1 - 0.0011 18.6 0.2 0.01 15.5 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family UCH PF00443.24 KFP03853.1 - 3.9e-59 199.9 0.7 4.6e-59 199.7 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP03853.1 - 3.7e-18 66.0 6.2 1e-17 64.5 4.3 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KFP03853.1 - 0.00041 19.6 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.1 KFP03853.1 - 0.014 14.6 1.5 0.16 11.2 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PFEMP PF03011.10 KFP03853.1 - 2.2 8.6 7.3 5.1 7.4 0.1 2.8 3 0 0 3 3 3 0 PFEMP DBL domain efThoc1 PF11957.3 KFP03854.1 - 1.8e-153 511.6 6.8 2.4e-153 511.1 4.7 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Death PF00531.17 KFP03854.1 - 7.4e-18 64.1 2.3 1.8e-17 62.9 0.4 2.5 3 0 0 3 3 3 1 Death domain Collagen PF01391.13 KFP03855.1 - 6.8e-24 83.1 103.6 1.1e-09 37.7 24.1 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Lectin_C PF00059.16 KFP03855.1 - 2.2e-21 76.4 1.8 2.2e-21 76.4 1.3 2.4 3 0 0 3 3 3 1 Lectin C-type domain Reo_sigmaC PF04582.7 KFP03855.1 - 0.006 15.8 37.5 0.036 13.2 3.4 4.0 1 1 3 4 4 4 3 Reovirus sigma C capsid protein Filament PF00038.16 KFP03855.1 - 0.02 14.3 35.6 0.011 15.2 21.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.5 KFP03855.1 - 0.23 11.5 37.8 0.078 13.0 3.8 3.8 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KFP03855.1 - 0.26 11.1 29.5 2.5 7.9 4.9 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KFP03855.1 - 0.52 8.9 35.6 0.39 9.3 11.0 3.0 1 1 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.4 KFP03855.1 - 0.76 8.6 30.4 0.32 9.9 7.7 2.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 WEMBL PF05701.6 KFP03855.1 - 2.4 6.5 31.3 2.1 6.6 17.9 2.4 1 1 1 2 2 2 0 Weak chloroplast movement under blue light IncA PF04156.9 KFP03855.1 - 4.3 6.8 36.5 0.99 8.9 3.2 3.9 3 1 1 4 4 4 0 IncA protein Clusterin PF01093.12 KFP03856.1 - 4.8e-136 454.0 12.1 5.5e-136 453.8 8.4 1.0 1 0 0 1 1 1 1 Clusterin DUF3482 PF11981.3 KFP03856.1 - 0.006 15.8 4.4 0.012 14.8 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3482) DUF1870 PF08965.5 KFP03856.1 - 0.029 14.0 0.4 0.2 11.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) Sulfatase_C PF14707.1 KFP03856.1 - 0.12 12.7 10.4 1.8 8.8 0.1 3.6 3 1 1 4 4 4 0 C-terminal region of aryl-sulfatase Thymidylat_synt PF00303.14 KFP03857.1 - 2.7e-125 416.8 0.0 3e-125 416.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Pkinase_Tyr PF07714.12 KFP03858.1 - 7.9e-94 313.5 0.0 1e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP03858.1 - 6.5e-50 169.6 0.0 9.3e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP03858.1 - 1.2e-28 98.6 0.2 2.5e-28 97.6 0.1 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFP03858.1 - 8.9e-21 73.0 0.4 3.8e-20 71.0 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFP03858.1 - 6.9e-16 57.5 0.0 1.8e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP03858.1 - 4.4e-12 45.3 0.0 1.2e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 KFP03858.1 - 0.011 15.4 0.0 0.064 12.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH3_3 PF08239.6 KFP03858.1 - 0.027 14.6 0.1 0.081 13.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain MT-A70 PF05063.9 KFP03859.1 - 1e-27 96.8 0.5 1.6e-27 96.1 0.4 1.3 1 0 0 1 1 1 1 MT-A70 Ndc80_HEC PF03801.8 KFP03860.1 - 8.8e-53 178.0 0.0 3.6e-52 176.0 0.0 2.1 1 0 0 1 1 1 1 HEC/Ndc80p family LPP PF04728.8 KFP03860.1 - 0.0098 15.6 0.0 0.045 13.5 0.0 2.2 1 1 0 1 1 1 1 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 KFP03860.1 - 0.011 14.9 0.4 0.011 14.9 0.3 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 KFP03860.1 - 0.021 14.7 1.4 0.021 14.7 1.0 5.6 4 2 2 6 6 6 0 bZIP transcription factor Cluap1 PF10234.4 KFP03860.1 - 0.5 9.5 0.0 0.5 9.5 0.0 4.9 3 1 2 5 5 5 0 Clusterin-associated protein-1 Atg14 PF10186.4 KFP03860.1 - 0.71 8.7 33.1 0.1 11.5 9.3 2.5 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 STAT_alpha PF01017.15 KFP03860.1 - 0.91 9.2 30.6 5.6 6.6 7.4 3.4 3 1 1 4 4 4 0 STAT protein, all-alpha domain APG6 PF04111.7 KFP03860.1 - 1.2 8.1 52.6 2.7 6.9 11.5 3.6 3 1 1 4 4 4 0 Autophagy protein Apg6 SPX PF03105.14 KFP03860.1 - 2.7 7.6 35.5 0.033 13.9 8.9 2.8 2 1 0 2 2 2 0 SPX domain IncA PF04156.9 KFP03860.1 - 5.4 6.5 49.3 8.6 5.9 15.4 3.9 2 2 0 2 2 2 0 IncA protein HATPase_c_3 PF13589.1 KFP03861.1 - 2.1e-15 56.5 0.0 4.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFP03861.1 - 8.1e-05 22.3 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Vinculin PF01044.14 KFP03862.1 - 5e-229 762.9 39.8 3.1e-179 598.1 16.3 2.0 1 1 1 2 2 2 2 Vinculin family AAA_32 PF13654.1 KFP03862.1 - 0.11 11.1 18.1 0.41 9.2 0.1 4.1 2 1 1 4 4 4 0 AAA domain LRR_8 PF13855.1 KFP03863.1 - 4.4e-59 196.0 61.1 1.4e-14 53.5 1.4 5.2 1 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFP03863.1 - 5.8e-31 105.5 35.0 1.1e-06 28.0 0.3 6.6 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP03863.1 - 5.9e-30 103.6 0.2 9.4e-13 47.9 0.2 3.1 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP03863.1 - 1.2e-19 67.3 37.1 0.011 15.6 0.5 11.1 11 0 0 11 11 11 8 Leucine Rich Repeat LRR_6 PF13516.1 KFP03863.1 - 2.2e-12 45.6 28.6 0.076 13.1 0.7 9.7 8 1 1 9 9 9 5 Leucine Rich repeat LRR_7 PF13504.1 KFP03863.1 - 2.7e-09 35.6 40.0 0.075 13.2 0.6 10.8 11 0 0 11 11 11 3 Leucine rich repeat LRR_9 PF14580.1 KFP03863.1 - 4.3e-07 29.6 2.9 0.011 15.3 0.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.13 KFP03863.1 - 4.4e-06 26.0 0.9 4.4e-06 26.0 0.6 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_2 PF07723.8 KFP03863.1 - 0.074 13.5 6.7 12 6.6 0.1 6.5 7 1 1 8 8 8 0 Leucine Rich Repeat EphA2_TM PF14575.1 KFP03863.1 - 0.16 12.3 0.1 0.69 10.3 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DnaJ PF00226.26 KFP03864.1 - 9.7e-18 63.6 0.3 2.5e-17 62.3 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain Luteo_P1-P2 PF08467.5 KFP03864.1 - 0.014 14.1 0.2 0.017 13.9 0.1 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase SIR2 PF02146.12 KFP03865.1 - 1.6e-62 210.3 0.0 2.9e-62 209.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KFP03865.1 - 0.005 16.4 0.2 0.0086 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KFP03865.1 - 0.029 14.1 0.0 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain HECT PF00632.20 KFP03866.1 - 2.2e-90 303.0 0.1 5.2e-90 301.8 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.13 KFP03866.1 - 3.1e-89 293.0 22.1 2.9e-15 56.2 0.0 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFP03866.1 - 1.9e-49 164.2 33.5 1.5e-10 40.3 0.3 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HLH PF00010.21 KFP03867.1 - 3.2e-18 65.1 0.1 4.7e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DERM PF14704.1 KFP03867.1 - 0.055 13.4 0.6 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Dermatopontin Amidoligase_2 PF12224.3 KFP03867.1 - 0.088 12.4 0.9 0.14 11.7 0.2 1.5 2 0 0 2 2 2 0 Putative amidoligase enzyme DUF1295 PF06966.7 KFP03867.1 - 0.09 12.0 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PhzC-PhzF PF02567.11 KFP03868.1 - 5.9e-59 199.5 0.0 6.9e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.14 KFP03868.1 - 0.043 13.7 0.0 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Diaminopimelate epimerase RRM_6 PF14259.1 KFP03869.1 - 4.5e-26 90.6 0.1 7e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP03869.1 - 1.6e-21 75.6 0.0 1.1e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP03869.1 - 0.00065 19.4 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dna2 PF08696.6 KFP03870.1 - 3.7e-69 232.2 0.2 7.5e-69 231.2 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KFP03870.1 - 1.7e-48 164.6 0.3 5.4e-31 107.5 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.1 KFP03870.1 - 2.8e-39 135.1 0.5 1.7e-36 125.9 0.3 3.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFP03870.1 - 2.1e-13 50.3 0.0 1.4e-12 47.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 KFP03870.1 - 3.2e-11 43.1 0.0 4.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KFP03870.1 - 2.6e-09 36.9 0.6 0.0021 17.6 0.1 4.2 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KFP03870.1 - 2e-07 30.6 0.1 6.2e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 KFP03870.1 - 0.00014 21.8 5.9 0.014 15.3 1.2 3.5 2 1 0 2 2 2 1 Domain of unknown function DUF83 CbiA PF01656.18 KFP03870.1 - 0.00021 20.7 0.0 0.0006 19.2 0.0 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD_C_2 PF13538.1 KFP03870.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain SRP54 PF00448.17 KFP03870.1 - 0.0017 17.8 0.0 0.0042 16.5 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 KFP03870.1 - 0.0066 16.1 0.2 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KFP03870.1 - 0.0069 15.8 0.1 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP03870.1 - 0.0094 15.9 0.2 0.031 14.2 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain UvrD-helicase PF00580.16 KFP03870.1 - 0.012 14.9 2.6 0.028 13.7 0.0 2.7 2 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain DUF853 PF05872.7 KFP03870.1 - 0.015 13.7 0.1 0.023 13.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PhoH PF02562.11 KFP03870.1 - 0.016 14.4 1.9 0.038 13.2 0.0 2.6 4 0 0 4 4 4 0 PhoH-like protein cobW PF02492.14 KFP03870.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KFP03870.1 - 0.018 15.2 0.1 0.06 13.5 0.1 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.1 KFP03870.1 - 0.019 14.4 2.3 0.58 9.5 0.0 3.0 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA_29 PF13555.1 KFP03870.1 - 0.024 14.1 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KFP03870.1 - 0.028 14.7 2.1 0.094 13.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KFP03870.1 - 0.05 13.7 0.0 0.32 11.1 0.0 2.5 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 KFP03870.1 - 0.052 14.3 0.0 0.18 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 KFP03870.1 - 0.074 12.6 0.0 0.26 10.8 0.0 2.0 2 1 0 2 2 1 0 Helicase ResIII PF04851.10 KFP03870.1 - 0.079 12.7 0.3 0.3 10.8 0.2 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 KFP03870.1 - 0.08 12.6 0.8 0.35 10.5 0.0 2.5 4 0 0 4 4 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KFP03870.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.22 KFP03871.1 - 1.2e-71 236.4 7.1 1.1e-23 82.7 0.8 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tet_JBP PF12851.2 KFP03872.1 - 1.8e-49 167.3 0.1 5.6e-49 165.7 0.1 1.9 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily zf-CXXC PF02008.15 KFP03872.1 - 1.3e-05 24.9 28.8 6.1e-05 22.7 20.0 2.3 1 0 0 1 1 1 1 CXXC zinc finger domain GUCT PF08152.7 KFP03873.1 - 2.2e-30 104.4 0.0 3.7e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.26 KFP03873.1 - 1.5e-26 92.0 0.0 8.7e-26 89.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain BBS1 PF14779.1 KFP03873.1 - 0.083 11.8 0.0 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 GUCT PF08152.7 KFP03874.1 - 3.6e-30 103.8 0.0 1.1e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 GUCT (NUC152) domain Helicase_C PF00271.26 KFP03874.1 - 2e-25 88.4 0.0 4.6e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FTR PF01913.13 KFP03874.1 - 0.052 13.2 0.2 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase CPL PF08144.6 KFP03874.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 CPL (NUC119) domain KBP_C PF12309.3 KFP03875.1 - 1.8e-141 471.4 11.9 1.8e-141 471.4 8.2 2.1 2 0 0 2 2 2 1 KIF-1 binding protein C terminal TPR_12 PF13424.1 KFP03875.1 - 0.00011 22.0 15.3 0.00033 20.5 3.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP03875.1 - 0.021 14.6 10.5 0.46 10.3 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFP03875.1 - 0.036 13.6 0.5 0.036 13.6 0.3 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat RGS PF00615.14 KFP03875.1 - 0.05 13.7 0.3 0.05 13.7 0.2 3.2 4 1 0 4 4 4 0 Regulator of G protein signaling domain Serglycin PF04360.7 KFP03876.1 - 6e-22 77.9 0.1 6.5e-22 77.8 0.1 1.0 1 0 0 1 1 1 1 Serglycin Vps26 PF03643.10 KFP03877.1 - 1.2e-132 440.8 6.4 1.4e-132 440.6 4.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFP03877.1 - 0.0024 17.6 0.3 0.37 10.5 0.0 3.1 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFP03877.1 - 0.022 14.8 0.0 0.066 13.3 0.0 2.0 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain SUV3_C PF12513.3 KFP03878.1 - 8.5e-18 63.5 0.1 2.2e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KFP03878.1 - 1.9e-12 46.8 0.0 5.6e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hexokinase_2 PF03727.11 KFP03879.1 - 1.3e-199 659.7 2.4 2e-103 344.8 0.4 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFP03879.1 - 5.7e-154 509.1 0.1 4.1e-82 274.5 0.0 2.3 2 0 0 2 2 2 2 Hexokinase CAS_CSE1 PF03378.10 KFP03879.1 - 0.014 13.7 0.0 0.9 7.7 0.0 2.8 3 0 0 3 3 3 0 CAS/CSE protein, C-terminus F420_ligase PF01996.11 KFP03879.1 - 0.062 12.3 0.1 1.4 7.9 0.0 2.4 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase Hexokinase_2 PF03727.11 KFP03880.1 - 2.9e-204 675.0 2.0 1.4e-103 345.3 0.4 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFP03880.1 - 4.4e-171 565.0 0.4 6.9e-85 283.5 0.0 2.3 2 0 0 2 2 2 2 Hexokinase CSD PF00313.17 KFP03880.1 - 0.011 15.5 0.0 0.42 10.4 0.0 2.7 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Sec23_helical PF04815.10 KFP03880.1 - 0.015 14.6 0.1 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 Sec23/Sec24 helical domain DUF1997 PF09366.5 KFP03880.1 - 0.044 13.5 0.0 3.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1997) 7tm_1 PF00001.16 KFP03881.1 - 4.3e-59 199.7 22.3 5.3e-59 199.4 15.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP03881.1 - 3.5e-08 32.9 24.6 4.5e-08 32.5 17.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.3 KFP03881.1 - 0.00017 21.1 6.2 0.00017 21.1 4.3 2.9 2 1 1 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 Herpes_US9 PF06072.6 KFP03881.1 - 0.18 11.6 1.9 0.39 10.5 0.0 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 RseC_MucC PF04246.7 KFP03881.1 - 2.8 7.5 6.8 1.5 8.3 1.9 2.4 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Tetraspannin PF00335.15 KFP03882.1 - 4.6e-36 124.1 10.7 5.7e-36 123.8 7.4 1.1 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 KFP03882.1 - 0.00094 18.9 0.8 0.00094 18.9 0.5 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 KFP03882.1 - 0.047 13.6 5.8 0.13 12.1 4.1 1.9 1 1 0 1 1 1 0 CD20-like family DUF202 PF02656.10 KFP03882.1 - 0.2 11.9 0.9 0.52 10.5 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TctB PF07331.6 KFP03882.1 - 5.1 6.7 12.4 0.56 9.8 4.1 2.3 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Macro PF01661.16 KFP03883.1 - 4.8e-25 87.7 0.1 8.2e-25 87.0 0.1 1.4 1 0 0 1 1 1 1 Macro domain Histone PF00125.19 KFP03883.1 - 7.5e-22 77.2 0.3 1.7e-21 76.1 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFP03883.1 - 0.0095 15.9 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Clp_N PF02861.15 KFP03883.1 - 0.035 14.0 1.0 0.13 12.2 0.0 2.5 3 0 0 3 3 3 0 Clp amino terminal domain Sulfotransfer_1 PF00685.22 KFP03884.1 - 2.1e-49 168.1 0.0 2.8e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP03884.1 - 0.00072 20.5 2.4 0.0015 19.4 1.6 1.7 1 1 0 1 1 1 1 Sulfotransferase family SapB_2 PF03489.12 KFP03885.1 - 9.9e-46 153.2 45.4 2.5e-13 49.7 1.5 6.5 7 0 0 7 7 7 4 Saposin-like type B, region 2 SapB_1 PF05184.10 KFP03885.1 - 1.8e-43 145.5 23.0 1.3e-12 47.2 0.2 5.9 5 0 0 5 5 5 4 Saposin-like type B, region 1 SapA PF02199.10 KFP03885.1 - 3.1e-17 62.0 8.4 3.1e-17 62.0 5.9 3.5 3 0 0 3 3 3 2 Saposin A-type domain TLE_N PF03920.10 KFP03885.1 - 0.00012 21.9 0.9 0.081 12.7 0.1 2.7 2 0 0 2 2 2 2 Groucho/TLE N-terminal Q-rich domain SapB_1 PF05184.10 KFP03886.1 - 9.4e-21 73.1 11.2 4.4e-12 45.5 1.7 2.7 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.12 KFP03886.1 - 1.1e-14 54.0 5.4 2.2e-08 33.9 0.6 3.2 3 0 0 3 3 3 2 Saposin-like type B, region 2 Cadherin PF00028.12 KFP03887.1 - 0 1457.5 40.5 1.2e-21 76.7 0.0 27.3 27 0 0 27 27 27 27 Cadherin domain Cadherin_2 PF08266.7 KFP03887.1 - 4.7e-20 70.9 0.0 0.76 9.3 0.0 13.4 14 0 0 14 14 14 5 Cadherin-like Rifin_STEVOR PF02009.11 KFP03887.1 - 1.9 8.0 0.2 3.1 7.3 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Ig_2 PF13895.1 KFP03888.1 - 1.8e-06 27.9 0.5 7.1e-06 26.0 0.4 2.0 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP03888.1 - 2e-06 27.6 0.0 4.2e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFP03888.1 - 0.005 16.9 1.2 0.1 12.7 0.8 2.5 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP03888.1 - 0.0062 16.3 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Nucleoside_tran PF01733.13 KFP03890.1 - 1.5e-68 231.2 8.4 1.5e-68 231.2 5.8 2.1 1 1 1 2 2 2 1 Nucleoside transporter ZU5 PF00791.15 KFP03891.1 - 1.3e-36 124.4 0.0 2.4e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain Death PF00531.17 KFP03891.1 - 1.2e-13 50.5 0.2 2.1e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Death domain I-set PF07679.11 KFP03891.1 - 2.1e-10 40.3 0.0 3.6e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin I-set domain TSP_1 PF00090.14 KFP03891.1 - 4.8e-10 39.3 26.0 1.1e-06 28.5 6.3 2.8 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.1 KFP03891.1 - 2.1e-09 37.3 0.3 5.2e-07 29.6 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Ig_3 PF13927.1 KFP03891.1 - 0.0022 18.4 0.0 0.02 15.4 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain PTCRA PF15028.1 KFP03891.1 - 0.0053 16.3 0.1 0.017 14.7 0.1 1.8 1 0 0 1 1 1 1 Pre-T-cell antigen receptor ig PF00047.20 KFP03891.1 - 0.012 15.6 0.0 0.012 15.6 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin domain Pterin_4a PF01329.14 KFP03892.1 - 4.1e-32 109.7 0.1 4.6e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Pyridoxal_deC PF00282.14 KFP03893.1 - 1.3e-19 69.9 0.0 2.2e-19 69.1 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFP03893.1 - 1.4e-14 53.5 0.0 1.1e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFP03893.1 - 0.0036 16.4 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 KFP03893.1 - 0.077 11.4 0.0 0.21 10.0 0.0 1.7 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Vitellogenin_N PF01347.17 KFP03894.1 - 1.1e-11 43.7 0.0 1.6e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region DUF1943 PF09172.6 KFP03894.1 - 1.9e-05 23.7 0.1 4.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) HEAT_2 PF13646.1 KFP03894.1 - 0.098 12.9 0.3 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 HEAT repeats Pep_M12B_propep PF01562.14 KFP03895.1 - 3e-25 88.5 0.0 6.3e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.14 KFP03895.1 - 2.4e-24 85.1 57.3 9.9e-11 41.5 4.3 5.9 5 0 0 5 5 5 4 Thrombospondin type 1 domain Reprolysin PF01421.14 KFP03895.1 - 4.3e-22 78.6 0.0 9.1e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_spacer1 PF05986.9 KFP03895.1 - 7.5e-22 77.3 0.0 1.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin_5 PF13688.1 KFP03895.1 - 9.8e-16 58.2 0.8 2.1e-15 57.1 0.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFP03895.1 - 1.2e-10 41.7 0.6 2.7e-10 40.5 0.4 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFP03895.1 - 4.3e-10 40.1 0.2 7.8e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP03895.1 - 8.2e-09 35.2 0.2 1.5e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFP03895.1 - 0.0017 18.0 0.2 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Matrixin PLAC PF08686.6 KFP03895.1 - 0.0021 18.3 4.8 0.0021 18.3 3.3 2.8 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain PTPlike_phytase PF14566.1 KFP03896.1 - 4e-68 228.1 0.1 1.8e-35 122.1 0.0 2.8 3 0 0 3 3 3 2 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFP03896.1 - 0.00016 21.0 0.0 0.071 12.4 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFP03896.1 - 0.0039 17.4 0.1 0.28 11.4 0.0 3.0 2 1 0 2 2 2 1 Tyrosine phosphatase family eIF_4EBP PF05456.6 KFP03897.1 - 1.3e-22 79.6 0.0 1.5e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) LRR_8 PF13855.1 KFP03898.1 - 2.4e-17 62.4 4.7 7.8e-09 35.1 0.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KFP03898.1 - 1.5e-16 59.5 6.3 4.6e-07 29.3 0.0 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP03898.1 - 5.5e-13 47.0 5.0 0.021 14.7 0.1 6.1 6 0 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.1 KFP03898.1 - 1.1e-07 31.1 2.9 1.3 9.3 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 KFP03898.1 - 2.8e-07 29.6 10.1 0.035 14.2 0.3 6.0 6 0 0 6 6 6 2 Leucine rich repeat LRR_9 PF14580.1 KFP03898.1 - 0.0024 17.4 0.2 0.0066 16.0 0.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat 7tm_1 PF00001.16 KFP03899.1 - 1.9e-60 204.2 16.5 1.9e-60 204.2 11.4 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP03899.1 - 3.9e-09 36.0 14.0 5.5e-09 35.5 9.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PLAC8 PF04749.12 KFP03899.1 - 0.77 10.3 5.4 0.67 10.5 0.9 2.5 2 0 0 2 2 2 0 PLAC8 family Pyrophosphatase PF00719.14 KFP03900.1 - 7.5e-56 187.9 0.6 9.2e-56 187.6 0.4 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Arf PF00025.16 KFP03901.1 - 1.1e-63 213.5 0.0 1.3e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFP03901.1 - 2.2e-09 36.8 0.0 2.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFP03901.1 - 2e-08 33.3 0.2 6.1e-06 25.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFP03901.1 - 3.1e-07 29.9 0.0 3.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP03901.1 - 9e-07 29.4 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFP03901.1 - 1.7e-05 24.7 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP03901.1 - 6.5e-05 22.4 0.0 0.00081 18.8 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP03901.1 - 0.002 17.3 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFP03901.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SPARC_Ca_bdg PF10591.4 KFP03902.1 - 1.8e-20 73.0 0.2 3.7e-20 72.0 0.1 1.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.13 KFP03902.1 - 2.7e-16 58.6 1.2 5.9e-16 57.5 0.8 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat EF-hand_7 PF13499.1 KFP03902.1 - 4.4e-05 23.5 0.0 8.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP03902.1 - 6.9e-05 22.4 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFP03902.1 - 0.00032 19.8 0.0 0.086 12.1 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFP03902.1 - 0.0075 15.8 0.0 0.079 12.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP03902.1 - 0.015 14.5 0.0 0.071 12.4 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.1 KFP03902.1 - 0.018 14.6 0.1 0.29 10.8 0.0 2.2 1 1 1 2 2 2 0 EF hand AKAP7_NLS PF10469.4 KFP03903.1 - 3.6e-60 203.2 0.1 4.4e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.24 KFP03903.1 - 7.9e-11 41.4 2.1 1.6e-10 40.4 1.4 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KFP03903.1 - 1.1e-07 31.3 1.8 2.1e-07 30.4 0.8 1.9 2 0 0 2 2 2 1 KH domain 2_5_RNA_ligase2 PF13563.1 KFP03903.1 - 0.0044 16.7 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily KH_2 PF07650.12 KFP03903.1 - 0.012 15.2 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 KH domain UPF0158 PF03682.8 KFP03903.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF2110 PF09883.4 KFP03904.1 - 0.019 14.5 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) RTP801_C PF07809.6 KFP03905.1 - 1e-38 131.5 0.0 1.3e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 RTP801 C-terminal region DUF1977 PF09320.6 KFP03906.1 - 1.8e-42 143.9 0.2 3.2e-42 143.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KFP03906.1 - 2e-27 94.6 1.3 3.1e-27 94.1 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 KFP03906.1 - 0.032 13.6 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF607 PF04678.8 KFP03908.1 - 7.2e-61 205.2 1.1 8.9e-61 204.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF607 DUF2960 PF11173.3 KFP03908.1 - 0.0086 16.3 0.0 0.041 14.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2960) Zona_pellucida PF00100.18 KFP03909.1 - 2.2e-43 148.6 0.5 4.8e-43 147.5 0.3 1.6 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.1 KFP03909.1 - 4.4e-18 65.1 30.9 1.1e-11 44.5 7.9 4.9 6 0 0 6 6 6 2 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP03909.1 - 0.0044 16.6 21.0 0.0062 16.1 0.3 4.5 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.2 KFP03909.1 - 0.012 15.6 6.7 0.012 15.6 4.6 4.6 5 0 0 5 5 5 0 EGF domain PLA2G12 PF06951.6 KFP03910.1 - 1.2e-88 295.6 8.0 1.3e-88 295.4 5.5 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) P4Ha_N PF08336.6 KFP03911.1 - 3.3e-44 149.9 0.1 3.3e-44 149.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.15 KFP03911.1 - 5.5e-13 49.0 0.0 1.2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KFP03911.1 - 1.5e-06 28.6 0.0 3.5e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fis1_TPR_C PF14853.1 KFP03911.1 - 0.0017 18.1 0.5 0.017 14.9 0.4 2.6 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 KFP03911.1 - 0.06 13.2 0.8 0.41 10.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFP03911.1 - 0.13 12.2 0.6 0.3 11.0 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat NUDIX PF00293.23 KFP03912.1 - 1.9e-15 56.6 0.1 3.6e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KFP03912.1 - 1.4e-12 47.7 0.0 3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KFP03912.1 - 2.4e-09 36.5 0.4 4.7e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain SGT1 PF07093.6 KFP03913.1 - 6.1e-159 530.1 2.0 7.1e-159 529.9 1.4 1.0 1 0 0 1 1 1 1 SGT1 protein Nse4-Nse3_bdg PF15412.1 KFP03913.1 - 0.13 12.1 4.7 3.4 7.5 2.6 3.0 3 0 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE DUF3719 PF12516.3 KFP03914.1 - 3.8e-20 71.2 0.3 1.3e-19 69.5 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) Ndc1_Nup PF09531.5 KFP03914.1 - 0.36 9.1 1.1 0.54 8.6 0.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF619 PF04768.8 KFP03915.1 - 0.051 12.9 0.7 0.19 11.1 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF619) DUF4407 PF14362.1 KFP03915.1 - 0.26 10.2 2.1 0.32 9.8 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.15 KFP03915.1 - 0.36 10.6 9.7 7.3 6.4 4.0 3.0 2 1 0 2 2 2 0 Prefoldin subunit DUF1963 PF09234.5 KFP03915.1 - 0.5 10.5 2.8 0.69 10.1 1.9 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1963) HrpJ PF07201.6 KFP03915.1 - 2.1 8.3 9.3 0.96 9.4 5.0 1.5 2 0 0 2 2 2 0 HrpJ-like domain Enkurin PF13864.1 KFP03915.1 - 2.8 8.2 10.8 4.4 7.5 4.6 2.7 2 1 0 2 2 2 0 Calmodulin-binding DUF4200 PF13863.1 KFP03915.1 - 8.6 6.3 18.6 11 5.9 5.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) HMG_box PF00505.14 KFP03916.1 - 1.7e-28 98.6 12.3 2.2e-20 72.6 3.7 3.0 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP03916.1 - 2e-17 63.3 13.7 4e-10 39.9 3.6 3.1 3 1 0 3 3 3 2 HMG-box domain YABBY PF04690.8 KFP03916.1 - 0.0068 16.6 0.2 0.0068 16.6 0.2 2.5 1 1 2 3 3 3 1 YABBY protein Metal_resist PF13801.1 KFP03916.1 - 0.23 11.4 7.9 0.17 11.9 2.1 2.5 2 1 0 2 2 2 0 Heavy-metal resistance Inhibitor_I9 PF05922.11 KFP03916.1 - 3.1 8.4 5.7 0.42 11.2 0.1 2.2 2 1 0 2 2 2 0 Peptidase inhibitor I9 UQ_con PF00179.21 KFP03917.1 - 6e-52 174.7 0.0 6.6e-52 174.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP03917.1 - 7e-05 22.6 0.0 8.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFP03917.1 - 0.00056 19.7 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFP03917.1 - 0.048 13.3 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain zf-CDGSH PF09360.5 KFP03918.1 - 2.8e-12 46.2 0.5 4.9e-12 45.4 0.4 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.4 KFP03918.1 - 4.4e-10 39.2 0.6 6.3e-10 38.7 0.4 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus IPK PF03770.11 KFP03919.1 - 8.9e-67 224.5 0.3 1.3e-66 224.0 0.2 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase GPAT_N PF14829.1 KFP03919.1 - 0.047 13.3 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal IRF PF00605.12 KFP03923.1 - 1e-18 67.0 0.0 1.1e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor IRF-3 PF10401.4 KFP03924.1 - 4e-18 65.6 0.7 5.9e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 Interferon-regulatory factor 3 Xpo1 PF08389.7 KFP03926.1 - 4.1e-25 88.4 0.5 6.5e-25 87.7 0.3 1.3 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 KFP03926.1 - 0.0034 17.2 0.3 0.018 14.9 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain PID PF00640.18 KFP03927.1 - 0.0052 16.7 0.0 0.034 14.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) FAST_1 PF06743.10 KFP03928.1 - 2.8e-05 23.7 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FAST kinase-like protein, subdomain 1 NEP PF10167.4 KFP03929.1 - 2.7e-28 98.0 0.0 2.9e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein F5_F8_type_C PF00754.20 KFP03930.1 - 2.9e-06 27.1 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Xlink PF00193.12 KFP03931.1 - 7.3e-47 157.3 1.5 1e-32 112.0 0.0 2.2 2 0 0 2 2 2 2 Extracellular link domain V-set PF07686.12 KFP03931.1 - 1.6e-11 44.1 0.0 2.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP03931.1 - 2.4e-07 30.5 0.0 5.1e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP03931.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Chordopox_A33R PF05966.7 KFP03931.1 - 6.4e-06 25.0 0.6 0.002 16.9 0.0 2.1 1 1 1 2 2 2 2 Chordopoxvirus A33R protein Ig_3 PF13927.1 KFP03931.1 - 0.0012 19.2 0.0 0.005 17.3 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP03931.1 - 0.0069 16.4 0.0 0.029 14.4 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Lectin_C PF00059.16 KFP03931.1 - 0.058 14.0 0.9 9.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Lectin C-type domain V-set_CD47 PF08204.6 KFP03931.1 - 0.085 12.6 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain DUF2781 PF10914.3 KFP03932.1 - 1.8e-20 73.2 7.1 5e-19 68.5 3.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2781) DUF2910 PF11139.3 KFP03932.1 - 0.028 13.5 0.4 0.1 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) Surp PF01805.15 KFP03933.1 - 6.5e-32 108.9 6.2 1.6e-16 59.6 0.1 2.9 3 0 0 3 3 3 2 Surp module G-patch PF01585.18 KFP03933.1 - 7.1e-15 54.5 3.0 7.1e-15 54.5 2.1 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KFP03933.1 - 2.6e-07 30.3 0.4 2.6e-07 30.3 0.3 3.5 4 0 0 4 4 4 1 DExH-box splicing factor binding site SWIRM PF04433.12 KFP03933.1 - 0.24 11.5 2.1 6.3 6.9 0.1 3.4 3 0 0 3 3 3 0 SWIRM domain Neur_chan_memb PF02932.11 KFP03933.1 - 1.7 8.5 3.2 4.4 7.1 2.2 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cohesin_load PF10345.4 KFP03934.1 - 9.1e-115 384.1 14.1 1e-114 383.9 9.8 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_11 PF13414.1 KFP03934.1 - 2.2e-11 43.2 8.1 0.00072 19.1 0.0 5.6 5 2 2 7 7 7 4 TPR repeat TPR_12 PF13424.1 KFP03934.1 - 6.6e-11 42.0 14.8 0.00056 19.7 0.1 6.0 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP03934.1 - 9.8e-08 31.3 7.6 0.17 11.8 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFP03934.1 - 3.7e-05 23.9 2.2 1.2 9.9 0.0 6.7 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFP03934.1 - 0.00018 21.3 0.6 2.1 8.3 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP03934.1 - 0.0002 20.8 4.8 0.65 9.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP03934.1 - 0.00027 21.2 5.7 0.0056 17.0 0.1 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP03934.1 - 0.00073 19.6 6.7 0.4 10.8 0.0 4.5 3 2 3 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFP03934.1 - 0.0027 17.2 5.1 1.6 8.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat HemY_N PF07219.8 KFP03934.1 - 0.003 17.0 0.1 0.023 14.2 0.0 2.4 2 1 0 2 2 2 1 HemY protein N-terminus TPR_21 PF09976.4 KFP03934.1 - 0.11 12.4 0.4 8.3 6.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat GATA PF00320.22 KFP03935.1 - 5.2e-05 22.5 6.9 0.00014 21.1 4.7 1.8 1 0 0 1 1 1 1 GATA zinc finger CarboxypepD_reg PF13620.1 KFP03936.1 - 1e-09 38.2 0.1 0.0011 18.9 0.0 3.0 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain Ig_2 PF13895.1 KFP03936.1 - 3.1e-09 36.8 0.0 5.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain DUF4480 PF13715.1 KFP03936.1 - 3.2e-08 33.5 0.0 2.7e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4480) TSP_1 PF00090.14 KFP03936.1 - 5.9e-08 32.7 11.3 1.7e-07 31.2 7.9 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain Ig_3 PF13927.1 KFP03936.1 - 3e-06 27.6 0.1 7.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP03936.1 - 3.6e-06 26.7 0.0 6.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFP03936.1 - 0.0034 17.4 0.1 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP03936.1 - 0.026 14.4 0.0 0.23 11.3 0.0 2.2 1 1 0 1 1 1 0 Immunoglobulin V-set domain DDA1 PF10172.4 KFP03937.1 - 1.1e-35 121.3 0.2 1.5e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase zf-H2C2_2 PF13465.1 KFP03938.1 - 6.1e-25 86.2 10.8 7.1e-12 45.0 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03938.1 - 5.3e-18 64.1 11.7 1.9e-07 31.0 0.1 3.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03938.1 - 8.3e-12 44.5 10.1 0.00014 21.9 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-RING_3 PF14369.1 KFP03938.1 - 4.4e-09 36.1 7.6 0.01 15.8 0.1 3.0 3 0 0 3 3 3 2 zinc-finger zf-C2H2_jaz PF12171.3 KFP03938.1 - 2.3e-08 33.9 0.0 0.021 14.9 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFP03938.1 - 7.9e-08 32.3 4.0 0.00014 21.8 0.0 2.4 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFP03938.1 - 1.2e-07 31.4 6.1 0.028 14.3 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFP03938.1 - 3.1e-06 27.0 5.8 0.023 14.6 3.2 3.0 1 1 1 2 2 2 2 Zinc ribbon domain DUF1610 PF07754.6 KFP03938.1 - 1.3e-05 25.1 19.8 0.0097 16.0 0.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1610) zf-C2HC_2 PF13913.1 KFP03938.1 - 2e-05 24.1 10.2 0.046 13.4 0.1 3.2 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 KFP03938.1 - 2e-05 23.5 14.4 0.091 12.0 0.5 3.2 3 0 0 3 3 3 3 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFP03938.1 - 4.5e-05 23.0 3.4 1.8 8.3 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFP03938.1 - 5.7e-05 22.6 4.1 1.5 8.4 0.0 3.1 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFP03938.1 - 0.00014 21.2 14.6 0.13 11.8 5.5 3.1 2 1 0 2 2 2 2 zinc-ribbon domain zf-BED PF02892.10 KFP03938.1 - 0.0007 19.3 7.0 0.032 13.9 0.3 2.7 2 1 1 3 3 3 2 BED zinc finger DZR PF12773.2 KFP03938.1 - 0.00097 18.9 5.3 0.035 13.9 3.7 2.4 1 1 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 KFP03938.1 - 0.001 18.6 12.5 0.35 10.5 0.3 3.1 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 Sgf11 PF08209.6 KFP03938.1 - 0.0013 17.9 6.3 1.3 8.3 0.1 3.3 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) zf-HIT PF04438.11 KFP03938.1 - 0.0022 17.5 9.7 0.13 11.9 0.3 3.1 3 0 0 3 3 3 2 HIT zinc finger zf-Mss51 PF13824.1 KFP03938.1 - 0.003 17.3 4.9 0.88 9.4 0.0 2.7 2 1 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-AN1 PF01428.11 KFP03938.1 - 0.0036 17.1 5.3 1.3 8.9 0.0 3.1 3 0 0 3 3 3 1 AN1-like Zinc finger CpXC PF14353.1 KFP03938.1 - 0.0039 17.1 4.1 2 8.3 0.1 3.0 1 1 1 2 2 2 0 CpXC protein zf-ISL3 PF14690.1 KFP03938.1 - 0.004 17.1 13.5 0.69 9.9 1.0 3.5 3 2 0 3 3 3 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-met PF12874.2 KFP03938.1 - 0.0042 17.2 4.9 0.96 9.7 0.0 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type XPA_N PF01286.13 KFP03938.1 - 0.0052 16.4 5.1 4.4 7.0 0.3 3.1 3 0 0 3 3 3 0 XPA protein N-terminal DUF329 PF03884.9 KFP03938.1 - 0.0055 16.2 5.1 5.7 6.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF329) C1_4 PF07975.7 KFP03938.1 - 0.0061 16.5 1.2 0.8 9.7 0.8 2.3 1 1 1 2 2 2 1 TFIIH C1-like domain zf-TRAF PF02176.13 KFP03938.1 - 0.007 16.7 0.7 0.065 13.6 0.0 2.0 1 1 1 2 2 2 2 TRAF-type zinc finger Zn_Tnp_IS1595 PF12760.2 KFP03938.1 - 0.0074 16.0 8.9 0.32 10.8 1.9 2.5 1 1 1 2 2 2 2 Transposase zinc-ribbon domain HypA PF01155.14 KFP03938.1 - 0.0085 15.7 1.4 1 9.0 0.1 2.0 1 1 0 1 1 1 1 Hydrogenase expression/synthesis hypA family TerY-C PF15616.1 KFP03938.1 - 0.0099 15.8 3.0 0.043 13.7 0.1 2.0 1 1 1 2 2 2 1 TerY-C metal binding domain SprT-like PF10263.4 KFP03938.1 - 0.01 15.5 0.6 0.022 14.4 0.4 1.6 1 1 0 1 1 1 0 SprT-like family TF_Zn_Ribbon PF08271.7 KFP03938.1 - 0.013 14.7 12.8 0.7 9.2 0.6 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding DUF2225 PF09986.4 KFP03938.1 - 0.015 14.8 0.7 1.3 8.4 0.0 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) FYVE PF01363.16 KFP03938.1 - 0.016 15.0 2.1 0.24 11.2 1.4 2.3 1 1 0 1 1 1 0 FYVE zinc finger Prok-RING_1 PF14446.1 KFP03938.1 - 0.016 14.8 2.9 9.2 6.0 0.1 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 IBR PF01485.16 KFP03938.1 - 0.017 14.9 2.8 0.36 10.7 1.9 2.2 1 1 0 1 1 1 0 IBR domain Ogr_Delta PF04606.7 KFP03938.1 - 0.025 14.2 8.8 0.095 12.3 1.3 2.7 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger TFIIS_C PF01096.13 KFP03938.1 - 0.034 13.7 8.0 3.4 7.3 0.1 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) C1_1 PF00130.17 KFP03938.1 - 0.039 13.6 0.4 9.9 5.9 0.1 2.4 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 KFP03938.1 - 0.04 14.0 0.9 3.4 7.9 0.0 2.1 1 1 0 1 1 1 0 CHY zinc finger Rad50_zn_hook PF04423.9 KFP03938.1 - 0.053 12.9 4.1 14 5.2 0.3 3.2 1 1 2 3 3 3 0 Rad50 zinc hook motif zf-RING_5 PF14634.1 KFP03938.1 - 0.056 13.1 3.2 4.2 7.1 0.2 2.5 1 1 1 2 2 2 0 zinc-RING finger domain DUF164 PF02591.10 KFP03938.1 - 0.062 13.1 7.4 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Putative zinc ribbon domain FYDLN_acid PF09538.5 KFP03938.1 - 0.07 13.7 3.5 7.8 7.1 0.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Elf1 PF05129.8 KFP03938.1 - 0.071 12.8 1.0 4.7 6.9 0.1 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like PRP21_like_P PF12230.3 KFP03938.1 - 0.073 12.5 0.0 2.8 7.3 0.0 2.2 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-TFIIB PF13453.1 KFP03938.1 - 0.087 12.0 5.9 0.56 9.4 0.8 2.6 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-CCHC_5 PF14787.1 KFP03938.1 - 0.098 12.1 14.8 1.4 8.4 0.8 3.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-C4_Topoisom PF01396.14 KFP03938.1 - 0.11 11.9 9.9 2.6 7.6 0.3 3.2 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-H2C2_5 PF13909.1 KFP03938.1 - 0.11 12.7 13.8 3.4 8.0 1.2 3.9 3 2 0 3 3 3 0 C2H2-type zinc-finger domain A2L_zn_ribbon PF08792.5 KFP03938.1 - 0.11 11.9 8.6 0.71 9.4 0.0 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-C2H2_2 PF12756.2 KFP03938.1 - 0.12 12.4 0.3 3.1 7.9 0.0 2.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_recom PF13408.1 KFP03938.1 - 0.13 12.5 7.2 0.15 12.3 1.0 2.4 1 1 0 2 2 2 0 Recombinase zinc beta ribbon domain HNH PF01844.18 KFP03938.1 - 0.16 11.8 4.3 8 6.4 0.0 3.0 3 0 0 3 3 3 0 HNH endonuclease Rubredoxin PF00301.15 KFP03938.1 - 0.17 11.7 7.2 8.6 6.3 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin DUF2296 PF10058.4 KFP03938.1 - 0.18 11.5 5.9 2.6 7.8 0.0 3.0 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-UBP PF02148.14 KFP03938.1 - 0.21 11.7 1.4 0.63 10.2 0.5 2.1 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DUF2321 PF10083.4 KFP03938.1 - 0.23 10.9 3.3 0.14 11.6 0.5 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Cys_rich_CPXG PF14255.1 KFP03938.1 - 0.23 11.3 7.1 7.1 6.5 0.1 3.3 3 0 0 3 3 3 0 Cysteine-rich CPXCG Ribosomal_L37ae PF01780.14 KFP03938.1 - 0.26 11.1 3.6 4.2 7.3 0.4 2.5 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-MIZ PF02891.15 KFP03938.1 - 0.26 10.8 2.4 7.2 6.2 0.0 2.6 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger OrfB_Zn_ribbon PF07282.6 KFP03938.1 - 0.27 10.9 7.0 3.3 7.4 0.9 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain ADK_lid PF05191.9 KFP03938.1 - 0.28 10.8 8.8 7.9 6.2 0.1 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid GAGA PF09237.6 KFP03938.1 - 0.29 10.7 4.3 0.66 9.6 0.1 2.7 1 1 2 3 3 3 0 GAGA factor zf-MYND PF01753.13 KFP03938.1 - 0.32 10.9 2.8 4.1 7.3 2.0 2.2 1 1 0 1 1 1 0 MYND finger zf-RING_2 PF13639.1 KFP03938.1 - 0.33 10.8 5.0 3.1 7.6 3.4 2.3 1 1 0 1 1 1 0 Ring finger domain YhfH PF14149.1 KFP03938.1 - 0.33 10.7 8.1 4.2 7.2 0.1 3.2 3 0 0 3 3 3 0 YhfH-like protein C1_3 PF07649.7 KFP03938.1 - 0.36 10.8 5.3 0.7 9.9 0.0 2.5 3 0 0 3 3 2 0 C1-like domain zinc-ribbons_6 PF07191.7 KFP03938.1 - 0.37 10.6 2.7 5.9 6.7 1.2 2.5 1 1 1 2 2 2 0 zinc-ribbons DUF2256 PF10013.4 KFP03938.1 - 0.41 10.4 3.9 39 4.0 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) PhnA_Zn_Ribbon PF08274.7 KFP03938.1 - 0.59 9.9 8.7 6.3 6.6 0.3 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-FPG_IleRS PF06827.9 KFP03938.1 - 0.74 9.5 5.6 29 4.4 0.2 3.2 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF1272 PF06906.6 KFP03938.1 - 0.76 9.6 7.1 12 5.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) Opy2 PF09463.5 KFP03938.1 - 0.83 9.8 11.0 7.1 6.8 0.1 3.1 3 0 0 3 3 3 0 Opy2 protein DUF35_N PF12172.3 KFP03938.1 - 1.1 9.2 8.5 17 5.4 0.1 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Lar_restr_allev PF14354.1 KFP03938.1 - 1.1 9.6 7.1 40 4.6 4.9 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-LITAF-like PF10601.4 KFP03938.1 - 1.3 8.9 5.6 23 4.9 0.0 3.0 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-NADH-PPase PF09297.6 KFP03938.1 - 1.4 8.4 7.5 24 4.5 0.1 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.8 KFP03938.1 - 1.6 8.3 3.6 2.7 7.5 1.2 2.2 1 1 1 2 2 2 0 CSL zinc finger zf-trcl PF13451.1 KFP03938.1 - 1.7 8.3 3.9 19 4.9 0.0 2.9 3 0 0 3 3 3 0 Probable zinc-binding domain DNA_RNApol_7kD PF03604.8 KFP03938.1 - 2 7.9 8.1 4.4 6.8 0.1 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L32p PF01783.18 KFP03938.1 - 2.4 8.3 4.6 29 4.9 0.1 2.9 1 1 2 3 3 3 0 Ribosomal L32p protein family zf-CHCC PF10276.4 KFP03938.1 - 2.4 8.0 5.7 15 5.5 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger domain Nudix_N_2 PF14803.1 KFP03938.1 - 2.5 7.8 9.6 29 4.4 0.2 3.3 3 0 0 3 3 3 0 Nudix N-terminal DUF4379 PF14311.1 KFP03938.1 - 2.5 7.9 5.0 17 5.3 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4379) Cys_rich_CWC PF14375.1 KFP03938.1 - 2.7 7.9 7.6 30 4.6 0.1 3.1 3 0 0 3 3 3 0 Cysteine-rich CWC zf-RING_4 PF14570.1 KFP03938.1 - 3.2 7.4 7.7 16 5.1 0.1 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF3797 PF12677.2 KFP03938.1 - 3.5 7.3 11.4 7.1 6.3 0.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3797) zf-IS66 PF13005.2 KFP03938.1 - 3.6 7.6 13.0 12 6.0 0.4 3.2 2 1 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-tcix PF14952.1 KFP03938.1 - 7 6.0 12.8 7 6.0 0.8 3.2 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding Prim_Zn_Ribbon PF08273.7 KFP03938.1 - 8.3 6.5 14.9 3.3 7.8 1.3 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase Trypsin PF00089.21 KFP03939.1 - 9.4e-31 107.0 0.1 1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP03939.1 - 0.005 16.1 0.2 0.008 15.4 0.1 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFP03939.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_A21 PF03566.8 KFP03940.1 - 0.0081 14.3 0.6 0.011 13.8 0.4 1.4 1 0 0 1 1 1 1 Peptidase family A21 Peptidase_S49_N PF08496.5 KFP03940.1 - 8.1 6.2 11.0 0.75 9.5 1.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RBD-FIP PF09457.5 KFP03941.1 - 8.6e-22 76.6 4.7 1.8e-21 75.6 3.3 1.6 1 0 0 1 1 1 1 FIP domain C2 PF00168.25 KFP03941.1 - 3.6e-17 61.9 0.0 1e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 C2 domain Yae1_N PF09811.4 KFP03942.1 - 8.9e-15 53.9 41.8 3.3e+03 -2.3 29.0 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-CCHC PF00098.18 KFP03943.1 - 2.1e-05 24.2 1.1 4e-05 23.3 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KFP03943.1 - 0.00058 19.2 3.2 0.036 13.5 0.2 3.1 3 0 0 3 3 3 1 GAG-polyprotein viral zinc-finger KH_1 PF00013.24 KFP03943.1 - 0.00099 18.7 0.5 0.0023 17.5 0.4 1.6 1 1 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 KFP03943.1 - 0.026 14.2 0.4 0.05 13.3 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle KH_3 PF13014.1 KFP03943.1 - 0.026 14.1 0.3 0.049 13.3 0.2 1.5 1 0 0 1 1 1 0 KH domain zf-CCHC_4 PF14392.1 KFP03943.1 - 0.23 11.1 1.3 0.45 10.2 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Transglut_C PF00927.17 KFP03945.1 - 8.2e-35 119.0 0.6 3e-17 62.6 0.0 2.7 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 KFP03945.1 - 2.5e-29 101.7 0.2 5.2e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 KFP03945.1 - 1.4e-15 57.4 0.2 2.8e-15 56.5 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily A2M_N PF01835.14 KFP03945.1 - 0.045 13.9 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 MG2 domain Poxvirus_B22R PF04395.7 KFP03945.1 - 0.12 11.9 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein Transglut_C PF00927.17 KFP03946.1 - 5.9e-29 100.2 0.5 2.4e-14 53.2 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 KFP03946.1 - 8.7e-28 96.7 0.0 2.6e-27 95.1 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase family Transglut_core PF01841.14 KFP03946.1 - 3.5e-17 62.6 0.2 9e-17 61.3 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.15 KFP03947.1 - 2.2e-28 98.6 0.0 4.9e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.17 KFP03947.1 - 1e-26 93.0 0.5 6.4e-15 55.1 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 KFP03947.1 - 1e-16 61.1 0.1 2.7e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_N PF00868.15 KFP03948.1 - 1.1e-29 102.8 0.0 2.1e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_C PF00927.17 KFP03948.1 - 2.7e-26 91.6 0.0 4.2e-15 55.7 0.0 3.5 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.14 KFP03948.1 - 7.5e-19 68.0 1.2 1.4e-18 67.1 0.8 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily GCIP PF13324.1 KFP03949.1 - 2.6e-80 269.5 2.0 3e-80 269.3 1.4 1.0 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting AAA_12 PF13087.1 KFP03950.1 - 1.9e-39 135.1 0.8 4e-39 134.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFP03950.1 - 1.4e-27 96.7 9.4 1.8e-25 89.8 6.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFP03950.1 - 4.9e-11 42.2 0.0 1.5e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFP03950.1 - 2.2e-07 30.6 0.4 0.0002 20.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KFP03950.1 - 0.00047 19.2 0.8 0.0035 16.3 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KFP03950.1 - 0.0015 18.4 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KFP03950.1 - 0.0018 17.6 0.5 0.0097 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KFP03950.1 - 0.0046 16.2 0.0 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 KFP03950.1 - 0.021 14.2 0.8 0.055 12.9 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 KFP03950.1 - 0.24 11.5 2.2 1.2 9.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 KFP03951.1 - 6.2e-47 159.2 0.1 2e-44 151.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP03951.1 - 2.2e-25 88.2 0.1 7.7e-25 86.5 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP03951.1 - 0.00076 19.3 0.1 0.00076 19.3 0.0 3.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFP03951.1 - 0.00099 19.2 1.7 0.002 18.2 0.1 2.4 3 1 0 3 3 3 1 AAA domain LSM PF01423.17 KFP03952.1 - 0.054 13.0 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 LSM domain DUF3361 PF11841.3 KFP03953.1 - 1.3e-73 245.9 6.0 3e-73 244.8 4.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 KFP03953.1 - 3.5e-46 156.8 0.2 6.1e-46 156.0 0.2 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family FERM_N PF09379.5 KFP03953.1 - 0.012 15.6 0.0 0.091 12.8 0.0 2.4 1 1 0 1 1 1 0 FERM N-terminal domain GDE_C PF06202.9 KFP03953.1 - 0.13 10.9 0.9 21 3.7 0.0 3.1 3 0 0 3 3 3 0 Amylo-alpha-1,6-glucosidase Cadherin PF00028.12 KFP03954.1 - 3e-83 274.1 11.8 2.8e-20 72.3 0.1 5.5 5 1 1 6 6 6 5 Cadherin domain Cadherin_C PF01049.12 KFP03954.1 - 8.9e-43 145.8 0.1 2e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFP03954.1 - 1.5e-05 24.4 0.1 1.8 8.2 0.0 4.4 4 0 0 4 4 4 2 Cadherin-like EphA2_TM PF14575.1 KFP03954.1 - 0.048 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.4 KFP03954.1 - 0.078 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 7TM_GPCR_Srw PF10324.4 KFP03954.1 - 0.19 10.8 0.1 0.29 10.2 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Big_3_4 PF13754.1 KFP03954.1 - 9.9 6.5 9.1 20 5.6 2.0 3.7 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) TNFR_c6 PF00020.13 KFP03955.1 - 5.1e-08 32.8 38.1 0.00024 21.0 6.1 4.5 4 0 0 4 4 4 3 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFP03955.1 - 0.0032 16.9 0.6 0.0032 16.9 0.4 4.2 4 1 1 5 5 5 2 GCC2 and GCC3 AA_permease PF00324.16 KFP03956.1 - 2.1e-51 174.7 22.2 2.9e-38 131.4 3.6 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KFP03956.1 - 5.7e-17 61.3 23.9 2.1e-15 56.1 16.6 2.1 1 1 0 1 1 1 1 Amino acid permease Peptidase_M10 PF00413.19 KFP03957.1 - 6.3e-67 224.1 0.0 7.3e-66 220.6 0.0 2.4 2 1 0 2 2 2 1 Matrixin fn2 PF00040.14 KFP03957.1 - 6.6e-59 195.6 33.5 8.6e-20 70.4 4.7 3.5 3 0 0 3 3 3 3 Fibronectin type II domain Hemopexin PF00045.14 KFP03957.1 - 4.4e-20 71.1 1.5 2.9e-08 33.2 0.1 3.7 3 1 0 3 3 3 3 Hemopexin PG_binding_1 PF01471.13 KFP03957.1 - 3.5e-06 26.8 0.4 8e-06 25.7 0.3 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 KFP03957.1 - 0.01 16.3 0.0 0.04 14.4 0.0 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 KFP03957.1 - 0.022 14.1 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 KFP03957.1 - 0.04 13.8 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFP03957.1 - 0.054 13.0 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP03957.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Homeobox_KN PF05920.6 KFP03958.1 - 1.4e-14 53.4 0.0 1.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFP03958.1 - 7.7e-07 28.6 0.1 8.1e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP03958.1 - 0.0014 17.6 0.2 0.0026 16.7 0.1 1.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 KFP03958.1 - 0.0047 17.0 0.1 0.0059 16.6 0.1 1.1 1 0 0 1 1 1 1 Helicase associated domain LBP_BPI_CETP_C PF02886.12 KFP03959.1 - 1.4e-59 201.1 0.6 2.5e-59 200.3 0.4 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 KFP03959.1 - 2.8e-32 111.3 0.3 2.3e-31 108.3 0.1 2.1 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain 7kD_coat PF02495.12 KFP03959.1 - 0.077 12.4 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 7kD viral coat protein Peptidase_S10 PF00450.17 KFP03960.1 - 2.2e-131 438.8 0.1 2.5e-131 438.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KFP03960.1 - 0.015 15.1 0.0 0.056 13.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP03960.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Neuralized PF07177.7 KFP03961.1 - 6.2e-22 77.2 0.0 1.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Neuralized SOCS_box PF07525.11 KFP03961.1 - 5.8e-10 38.8 1.8 5.8e-10 38.8 1.2 1.7 2 0 0 2 2 2 1 SOCS box 4HBT_3 PF13622.1 KFP03962.1 - 3e-42 145.1 0.4 3.7e-42 144.8 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KFP03962.1 - 8.8e-37 125.6 0.0 5.4e-27 94.0 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase EF-hand_1 PF00036.27 KFP03964.1 - 1.2e-26 89.8 23.1 2e-08 32.9 0.5 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KFP03964.1 - 1.5e-26 91.7 19.0 4.5e-13 48.5 0.4 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.1 KFP03964.1 - 2.2e-25 88.5 10.6 2.8e-12 46.5 1.6 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP03964.1 - 4.2e-21 72.8 14.1 4.3e-06 26.1 0.1 5.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KFP03964.1 - 1.7e-17 61.8 18.9 0.00037 19.6 0.2 5.1 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.1 KFP03964.1 - 2.6e-12 46.4 0.2 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFP03964.1 - 3.9e-08 32.9 3.2 0.0024 17.5 0.1 2.8 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFP03964.1 - 0.00019 21.4 0.7 0.077 13.0 0.2 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SpoVIF PF14069.1 KFP03964.1 - 0.00082 19.0 0.7 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Stage VI sporulation protein F TerB PF05099.8 KFP03964.1 - 0.0015 18.3 5.9 0.27 10.9 0.5 2.2 2 0 0 2 2 2 2 Tellurite resistance protein TerB FlgD PF03963.9 KFP03964.1 - 0.0087 16.1 0.2 1.7 8.7 0.0 2.3 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region DUF1456 PF07308.8 KFP03964.1 - 0.011 15.7 3.9 0.13 12.2 0.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1456) PTS_2-RNA PF01885.11 KFP03964.1 - 0.038 13.2 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family LolA PF03548.10 KFP03965.1 - 0.14 11.7 0.0 3.8 7.1 0.0 2.4 2 1 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA Kunitz_BPTI PF00014.18 KFP03966.1 - 7.8e-18 64.4 12.8 1.1e-17 63.9 8.9 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain zf-C4 PF00105.13 KFP03966.1 - 0.13 12.5 5.4 0.13 12.4 3.7 1.3 1 1 0 1 1 1 0 Zinc finger, C4 type (two domains) WAP PF00095.16 KFP03967.1 - 2.8e-12 46.3 16.2 4.8e-12 45.6 11.2 1.4 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' CTNNBL PF08216.6 KFP03968.1 - 1.4e-43 146.8 4.7 1.4e-43 146.8 3.3 2.1 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KFP03968.1 - 0.00012 21.7 4.2 1.7 8.5 0.1 3.8 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat DUF4020 PF13212.1 KFP03968.1 - 0.018 14.6 1.1 0.074 12.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) Vac14_Fab1_bd PF12755.2 KFP03969.1 - 0.012 16.0 0.0 4 7.8 0.0 4.1 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region VHS PF00790.14 KFP03969.1 - 0.015 14.9 0.6 0.9 9.1 0.0 3.9 4 0 0 4 4 4 0 VHS domain HEAT_2 PF13646.1 KFP03969.1 - 0.027 14.7 13.2 0.039 14.2 0.1 5.1 5 1 0 5 5 5 0 HEAT repeats DUF493 PF04359.9 KFP03969.1 - 0.16 12.3 0.0 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF493) CTD_bind PF04818.8 KFP03970.1 - 7.3e-26 90.2 1.2 8.6e-25 86.7 0.0 3.1 4 0 0 4 4 4 1 RNA polymerase II-binding domain. DUF2294 PF10057.4 KFP03970.1 - 0.0095 15.5 0.9 0.021 14.4 0.2 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2294) CTK3 PF12243.3 KFP03970.1 - 0.068 12.8 0.9 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 FimP PF09766.4 KFP03970.1 - 0.29 10.1 11.9 0.026 13.6 3.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein OmpH PF03938.9 KFP03970.1 - 1.9 8.4 11.1 6 6.7 6.5 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) FemAB PF02388.11 KFP03970.1 - 4.9 5.7 8.9 0.11 11.2 1.6 1.5 2 0 0 2 2 2 0 FemAB family Transglut_C PF00927.17 KFP03971.1 - 4.8e-49 164.8 0.0 4e-25 87.9 0.0 2.7 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.15 KFP03971.1 - 1e-34 119.1 0.0 1.8e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.14 KFP03971.1 - 1e-17 64.3 0.7 2.1e-17 63.3 0.5 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily CRAL_TRIO_2 PF13716.1 KFP03972.1 - 5e-07 29.7 0.0 2.6e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain LBP_BPI_CETP_C PF02886.12 KFP03974.1 - 6.3e-66 222.0 0.5 9.1e-66 221.4 0.3 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 KFP03974.1 - 8.6e-35 119.5 0.0 1.8e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.6 KFP03974.1 - 0.017 13.9 0.0 0.027 13.2 0.0 1.4 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) Radical_SAM PF04055.16 KFP03975.1 - 1.5e-37 129.3 0.0 3.1e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 KFP03975.1 - 1.9e-29 101.3 0.0 3.9e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 KFP03975.1 - 4.6e-11 42.3 0.0 8.4e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 TRAM domain LBP_BPI_CETP_C PF02886.12 KFP03976.1 - 2.2e-08 33.6 2.4 6.5e-08 32.0 0.8 2.3 2 1 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.20 KFP03976.1 - 3.8e-06 26.3 0.9 9.6e-05 21.7 0.1 2.6 1 1 1 2 2 2 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP PF01273.20 KFP03977.1 - 4.5e-20 71.6 7.9 4.5e-20 71.6 5.5 2.0 2 1 1 3 3 3 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP_C PF02886.12 KFP03977.1 - 3.3e-13 49.4 2.6 1e-12 47.8 0.1 2.4 2 1 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain EB1 PF03271.12 KFP03978.1 - 4.2e-17 61.9 0.7 1.6e-16 60.0 0.5 2.0 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 KFP03978.1 - 3.4e-12 46.3 0.3 4.2e-11 42.8 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP03978.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 CAMSAP CH domain PWWP PF00855.12 KFP03979.1 - 1.6e-09 37.8 2.5 5.9e-08 32.8 0.4 3.1 2 1 0 2 2 2 1 PWWP domain DNA_methylase PF00145.12 KFP03979.1 - 2.5e-08 33.4 0.0 1.2e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase HCaRG PF07258.9 KFP03980.1 - 1.1e-33 116.2 0.4 1.2e-33 116.1 0.3 1.0 1 0 0 1 1 1 1 HCaRG protein zf-H2C2 PF09337.5 KFP03981.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.5 1 1 0 1 1 1 0 His(2)-Cys(2) zinc finger ASXH PF13919.1 KFP03983.1 - 2.9e-50 169.6 0.1 6.3e-50 168.5 0.1 1.6 1 0 0 1 1 1 1 Asx homology domain HARE-HTH PF05066.8 KFP03983.1 - 2.5e-14 53.3 0.0 7.1e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain Kinesin PF00225.18 KFP03984.1 - 3.8e-120 400.5 0.6 3.8e-120 400.5 0.4 2.1 2 0 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 KFP03984.1 - 0.24 11.5 3.2 0.39 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain O-FucT PF10250.4 KFP03985.1 - 6.3e-69 232.7 0.0 7.2e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-H2C2_2 PF13465.1 KFP03986.1 - 9.9e-20 69.7 56.6 1.4e-05 25.0 1.9 7.8 7 1 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFP03986.1 - 1e-18 66.4 57.0 6.2e-05 23.0 1.3 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP03986.1 - 3e-17 61.5 50.3 0.002 18.3 0.8 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP03986.1 - 7e-05 22.5 0.2 7e-05 22.5 0.1 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP03986.1 - 0.0015 18.6 37.0 0.032 14.3 0.4 6.2 5 1 1 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFP03986.1 - 0.0054 16.8 33.6 0.14 12.2 1.4 4.8 2 1 3 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFP03986.1 - 0.009 16.1 18.4 1.6 9.0 0.1 4.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Equine_IAV_S2 PF06502.6 KFP03986.1 - 1.4 8.8 3.9 0.41 10.5 0.2 2.0 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein zf-C2H2_2 PF12756.2 KFP03986.1 - 2.6 8.2 34.0 7 6.8 1.0 5.5 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.5 KFP03986.1 - 8.1 7.0 7.3 1.2e+02 3.3 0.0 3.8 2 2 1 3 3 3 0 Protein of unknown function (FYDLN_acid) EMP70 PF02990.11 KFP03987.1 - 8.7e-226 750.3 13.3 1.1e-225 750.0 9.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4229 PF14012.1 KFP03987.1 - 0.38 10.6 0.0 0.38 10.6 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF4229) XK-related PF09815.4 KFP03988.1 - 2.9e-85 286.1 17.8 3.3e-85 286.0 12.4 1.0 1 0 0 1 1 1 1 XK-related protein DSPc PF00782.15 KFP03989.1 - 4.4e-33 113.6 0.0 5.8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFP03989.1 - 1.5e-07 31.6 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFP03989.1 - 7.1e-07 28.7 0.0 9.7e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFP03989.1 - 0.073 13.3 0.4 0.56 10.4 0.1 2.2 2 1 1 3 3 3 0 Tyrosine phosphatase family Pkinase PF00069.20 KFP03990.1 - 1.9e-20 73.1 0.0 2.3e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03990.1 - 2.5e-05 23.4 0.0 3.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TPX2_importin PF12214.3 KFP03991.1 - 1.8e-59 200.7 56.2 7.1e-59 198.8 4.5 5.7 3 2 2 5 5 5 3 Cell cycle regulated microtubule associated protein Aurora-A_bind PF09041.5 KFP03991.1 - 3.8e-26 90.6 0.9 1e-25 89.2 0.6 1.8 1 0 0 1 1 1 1 Aurora-A binding TPX2 PF06886.6 KFP03991.1 - 1.3e-13 50.8 16.3 1.3e-13 50.8 11.3 7.6 9 0 0 9 9 9 1 Targeting protein for Xklp2 (TPX2) ACCA PF03255.9 KFP03991.1 - 0.87 9.1 6.2 0.35 10.4 0.7 2.9 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LBP_BPI_CETP_C PF02886.12 KFP03992.1 - 2.1e-25 89.3 0.0 2.6e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Peptidase_A22B PF04258.8 KFP03993.1 - 7.6e-98 327.6 8.2 8.9e-98 327.4 5.7 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KFP03993.1 - 0.0004 19.6 9.3 0.0004 19.6 5.5 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) Presenilin PF01080.12 KFP03993.1 - 0.0019 17.1 1.1 0.0031 16.4 0.8 1.4 1 0 0 1 1 1 1 Presenilin DUF4345 PF14248.1 KFP03993.1 - 0.039 13.3 0.2 0.039 13.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Miro PF08477.8 KFP03994.1 - 3.3e-19 69.5 0.0 3.9e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFP03994.1 - 3.5e-19 68.7 0.0 4.1e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 KFP03994.1 - 7.2e-06 25.3 0.0 1.3e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KFP03994.1 - 0.0001 22.2 0.0 0.00017 21.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KFP03994.1 - 0.00056 20.2 0.0 0.0006 20.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Arf PF00025.16 KFP03994.1 - 0.0017 17.6 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.1 KFP03994.1 - 0.0018 18.3 0.1 0.0022 18.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFP03994.1 - 0.0027 16.9 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 KFP03994.1 - 0.0051 16.4 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFP03994.1 - 0.011 15.4 0.3 0.11 12.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFP03994.1 - 0.014 15.5 0.1 0.12 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFP03994.1 - 0.014 15.5 0.2 0.092 12.9 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.22 KFP03994.1 - 0.034 13.5 0.0 3 7.2 0.0 2.2 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 KFP03994.1 - 0.046 13.6 0.2 0.081 12.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KFP03994.1 - 0.056 12.8 0.1 1 8.8 0.0 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4618 PF15397.1 KFP03995.1 - 3.1e-36 125.0 22.6 8.1e-21 74.5 3.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) PilJ PF13675.1 KFP03995.1 - 0.034 14.4 5.1 6.6 7.0 3.6 2.7 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term IQ-like PF15157.1 KFP03995.1 - 0.046 13.9 3.2 0.045 13.9 1.1 1.9 1 1 0 1 1 1 0 IQ-like DUF1664 PF07889.7 KFP03995.1 - 0.052 13.3 16.2 0.21 11.3 1.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KFP03995.1 - 0.1 11.2 25.1 0.016 13.8 9.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein COG5 PF10392.4 KFP03995.1 - 0.11 12.5 10.1 0.21 11.5 0.4 3.0 1 1 0 2 2 2 0 Golgi transport complex subunit 5 Matrilin_ccoil PF10393.4 KFP03995.1 - 0.16 11.3 5.7 0.16 11.3 1.9 2.6 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin IL11 PF07400.6 KFP03995.1 - 0.19 11.2 1.1 0.28 10.6 0.3 1.7 2 0 0 2 2 2 0 Interleukin 11 Syntaxin-6_N PF09177.6 KFP03995.1 - 0.23 11.8 14.3 0.88 10.0 4.5 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Med9 PF07544.8 KFP03995.1 - 0.3 10.8 18.9 0.44 10.3 1.1 4.0 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.1 KFP03995.1 - 0.33 9.3 16.6 0.39 9.1 11.5 1.0 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 KFP03995.1 - 0.37 10.7 10.4 6.2 6.8 0.1 3.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 KFP03995.1 - 0.51 9.4 2.9 0.75 8.9 1.0 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1469 PF07332.6 KFP03995.1 - 0.58 9.8 3.4 0.41 10.3 0.6 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) HlyD PF00529.15 KFP03995.1 - 0.65 9.2 17.4 0.79 8.9 7.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein ATG16 PF08614.6 KFP03995.1 - 0.97 9.2 25.4 2.8 7.7 10.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 KFP03995.1 - 1 9.6 12.8 3.6 7.9 1.5 3.1 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 KFP03995.1 - 1.3 9.2 16.4 3.5 7.8 0.8 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Birna_RdRp PF04197.7 KFP03995.1 - 1.4 6.8 7.5 1.7 6.5 5.2 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF935 PF06074.7 KFP03995.1 - 1.7 7.2 12.0 0.8 8.3 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF935) DUF641 PF04859.7 KFP03995.1 - 3.6 7.3 17.7 0.38 10.5 6.0 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HSCB_C PF07743.8 KFP03995.1 - 5.9 7.4 20.3 3.1 8.3 2.4 3.1 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain MbeD_MobD PF04899.7 KFP03995.1 - 6.3 6.7 13.0 4.1 7.3 5.5 2.6 2 1 0 2 2 2 0 MbeD/MobD like KxDL PF10241.4 KFP03995.1 - 7.1 6.6 13.6 0.67 9.8 3.9 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein H-kinase_dim PF02895.9 KFP03995.1 - 8.4 6.8 16.3 0.96 9.8 1.9 3.0 2 2 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF1759 PF03564.10 KFP03995.1 - 9.6 6.0 9.1 11 5.8 1.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) RabGAP-TBC PF00566.13 KFP03996.1 - 1.5e-31 109.5 0.1 2.1e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1030 PF06270.6 KFP03996.1 - 0.11 12.0 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1030) Pkinase PF00069.20 KFP03997.1 - 5.3e-66 222.4 0.3 6.3e-66 222.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP03997.1 - 3.5e-21 75.4 0.0 4.8e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP03997.1 - 6.3e-08 32.6 0.0 1.8e-05 24.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP03997.1 - 0.0018 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFP03997.1 - 0.0049 16.4 1.6 0.0056 16.2 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KFP03997.1 - 0.072 12.0 0.0 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF1011 PF06237.7 KFP03998.1 - 6.7e-41 138.3 9.5 6.7e-41 138.3 6.6 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1011) Fibrinogen_C PF00147.13 KFP03999.1 - 3.6e-65 219.8 0.5 7.6e-65 218.7 0.0 1.7 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain ACT_6 PF13740.1 KFP03999.1 - 0.15 11.7 0.8 0.27 10.9 0.5 1.3 1 0 0 1 1 1 0 ACT domain TSP_1 PF00090.14 KFP04000.1 - 2.8e-05 24.1 9.8 2.8e-05 24.1 6.8 3.0 2 1 0 2 2 2 1 Thrombospondin type 1 domain Fer4_3 PF12798.2 KFP04000.1 - 0.045 14.3 19.3 0.13 12.8 0.0 6.4 6 2 0 6 6 6 0 4Fe-4S binding domain PI31_Prot_N PF11566.3 KFP04001.1 - 2.1e-19 69.6 0.0 2.8e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KFP04001.1 - 3.8e-10 40.2 12.1 9.4e-10 39.0 8.4 1.7 1 0 0 1 1 1 1 PI31 proteasome regulator Rad21_Rec8_N PF04825.8 KFP04002.1 - 1.7e-39 134.1 0.1 3.8e-39 133.0 0.0 1.6 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein PDZ PF00595.19 KFP04003.1 - 1.4e-20 73.2 4.4 7.2e-12 45.3 0.0 2.7 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP04003.1 - 6.1e-11 42.0 0.8 1.4e-06 28.1 0.0 2.3 1 1 1 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 KFP04003.1 - 0.0016 18.2 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain FKBP_C PF00254.23 KFP04004.1 - 4.4e-28 97.1 0.0 4.8e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SEP PF08059.8 KFP04005.1 - 5.3e-28 97.1 0.4 1.4e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KFP04005.1 - 3.1e-19 68.8 0.0 5.6e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 KFP04005.1 - 0.03 13.6 0.0 0.079 12.2 0.0 1.8 1 1 0 1 1 1 0 Spt20 family V-set PF07686.12 KFP04006.1 - 9.8e-11 41.5 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP04006.1 - 8.2e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP04006.1 - 5.4e-07 30.0 0.2 1.1e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP04006.1 - 1.6e-06 27.9 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFP04006.1 - 4.9e-05 23.3 0.7 0.00024 21.1 0.5 2.0 1 1 0 1 1 1 1 Immunoglobulin domain CD34_antigen PF06365.7 KFP04006.1 - 0.041 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family C2-set_2 PF08205.7 KFP04006.1 - 0.06 13.2 0.4 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain DAG1 PF05454.6 KFP04006.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RRN7 PF11781.3 KFP04006.1 - 0.11 11.9 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 SKG6 PF08693.5 KFP04006.1 - 0.23 10.7 2.8 0.39 10.0 2.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LST1 PF05083.8 KFP04006.1 - 4.2 7.4 6.3 42 4.2 4.4 2.2 1 1 0 1 1 1 0 LST-1 protein Pkinase PF00069.20 KFP04007.1 - 8e-41 139.9 0.0 1.1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04007.1 - 3.3e-24 85.3 0.0 2.9e-23 82.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFP04007.1 - 0.00056 19.0 0.0 0.00091 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP04007.1 - 0.0035 17.1 0.0 0.014 15.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFP04007.1 - 0.0046 15.9 0.0 0.012 14.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFP04007.1 - 0.0051 16.1 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 KFP04007.1 - 0.021 13.6 0.1 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PhaC_N PF07167.8 KFP04007.1 - 0.033 13.6 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus RIO1 PF01163.17 KFP04007.1 - 0.04 13.2 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family fn3 PF00041.16 KFP04008.1 - 1.6e-06 28.1 0.1 3.3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain AAA_11 PF13086.1 KFP04009.1 - 2.1e-75 253.3 2.4 3.4e-49 167.5 0.3 4.0 2 1 1 3 3 3 3 AAA domain AAA_12 PF13087.1 KFP04009.1 - 7.9e-72 240.8 0.8 5.7e-45 153.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNB PF00773.14 KFP04009.1 - 5.4e-57 193.5 0.1 1.4e-56 192.1 0.0 1.8 1 1 0 1 1 1 1 RNB domain AAA_19 PF13245.1 KFP04009.1 - 2.5e-17 62.3 0.0 4.1e-08 32.8 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 KFP04009.1 - 2.8e-15 56.4 0.0 0.0015 18.1 0.0 4.5 3 1 0 3 3 3 3 AAA domain AAA_22 PF13401.1 KFP04009.1 - 6.9e-08 32.6 0.0 0.022 14.8 0.0 4.2 3 1 0 3 3 3 2 AAA domain UvrD_C_2 PF13538.1 KFP04009.1 - 1.9e-06 27.9 0.8 0.0007 19.7 0.0 3.0 3 0 0 3 3 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KFP04009.1 - 5.4e-06 26.0 3.3 0.021 14.3 0.1 4.5 3 2 2 5 5 5 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KFP04009.1 - 1.2e-05 24.6 0.2 0.93 8.6 0.0 4.1 4 0 0 4 4 4 2 PhoH-like protein ResIII PF04851.10 KFP04009.1 - 1.4e-05 25.0 0.1 0.2 11.4 0.0 3.1 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KFP04009.1 - 2.5e-05 23.7 0.0 0.0053 16.0 0.0 3.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain zf-met PF12874.2 KFP04009.1 - 4.4e-05 23.5 3.6 0.00019 21.5 2.5 2.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF2075 PF09848.4 KFP04009.1 - 5e-05 22.4 0.0 0.00061 18.8 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.1 KFP04009.1 - 0.0012 18.3 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA PF00004.24 KFP04009.1 - 0.0016 18.6 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFP04009.1 - 0.0022 18.0 0.0 3.3 7.6 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KFP04009.1 - 0.0089 15.9 0.0 59 3.5 0.0 4.8 5 0 0 5 5 5 0 AAA domain T2SE PF00437.15 KFP04009.1 - 0.01 14.7 0.1 1.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 KFP04009.1 - 0.046 13.3 0.4 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFP04009.1 - 0.055 12.8 0.0 4.4 6.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KFP04009.1 - 0.067 13.5 0.1 0.72 10.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 KFP04009.1 - 0.069 12.8 0.1 4.9 6.7 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase Bac_DnaA PF00308.13 KFP04009.1 - 0.072 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_5 PF07728.9 KFP04009.1 - 0.088 12.5 0.0 18 5.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 KFP04009.1 - 0.098 12.1 0.3 17 4.8 0.0 3.2 3 1 0 3 3 2 0 DEAD/DEAH box helicase KaiC PF06745.8 KFP04009.1 - 0.13 11.3 0.0 1.9 7.5 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_10 PF12846.2 KFP04009.1 - 0.38 10.1 0.0 22 4.3 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain zf-C2H2_jaz PF12171.3 KFP04009.1 - 0.62 10.2 10.5 0.021 14.9 1.1 3.1 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding SAND PF01342.16 KFP04010.1 - 4.8e-36 122.3 0.0 9.1e-36 121.4 0.0 1.4 1 0 0 1 1 1 1 SAND domain Spc7 PF08317.6 KFP04010.1 - 0.063 11.9 1.1 0.12 11.0 0.2 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 KFP04010.1 - 0.099 12.2 0.5 0.16 11.5 0.4 1.3 1 0 0 1 1 1 0 IncA protein Stathmin PF00836.14 KFP04011.1 - 3.3e-54 182.3 13.2 4e-54 182.0 9.2 1.1 1 0 0 1 1 1 1 Stathmin family Arf PF00025.16 KFP04012.1 - 1.4e-46 157.8 0.1 1.9e-46 157.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP04012.1 - 2.3e-14 53.1 0.0 2.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP04012.1 - 2.7e-13 50.4 0.0 3.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KFP04012.1 - 3.3e-11 42.5 0.1 2.1e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFP04012.1 - 1.4e-10 40.6 0.0 1.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFP04012.1 - 1.9e-07 31.0 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP04012.1 - 3.4e-07 29.6 0.0 4.1e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP04012.1 - 0.0046 16.4 0.1 0.025 14.0 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KFP04012.1 - 0.012 15.9 0.1 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFP04012.1 - 0.031 14.4 0.0 0.29 11.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFP04012.1 - 0.032 13.9 0.2 0.17 11.5 0.1 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KFP04012.1 - 0.092 12.6 0.5 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain G-patch PF01585.18 KFP04013.1 - 3.5e-11 42.7 0.5 1.3e-10 40.9 0.4 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFP04013.1 - 0.19 11.6 0.0 0.19 11.6 0.0 2.9 3 0 0 3 3 3 0 DExH-box splicing factor binding site FAM176 PF14851.1 KFP04013.1 - 0.49 10.0 3.8 6.3 6.4 1.2 2.5 2 0 0 2 2 2 0 FAM176 family zf-CCCH PF00642.19 KFP04013.1 - 0.54 10.0 2.2 0.98 9.1 1.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFP04013.1 - 2.3 8.3 4.4 4.2 7.5 3.0 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type TPD52 PF04201.10 KFP04016.1 - 6.3e-55 185.3 2.1 5.5e-54 182.2 1.4 1.9 1 1 0 1 1 1 1 Tumour protein D52 family DUF641 PF04859.7 KFP04016.1 - 0.12 12.1 0.3 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) VASP_tetra PF08776.6 KFP04016.1 - 0.16 11.2 1.3 0.62 9.4 0.9 1.8 2 0 0 2 2 2 0 VASP tetramerisation domain DnaJ PF00226.26 KFP04017.1 - 3.9e-27 93.7 2.6 5.9e-27 93.1 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain GP41 PF00517.12 KFP04017.1 - 0.0043 16.6 0.0 0.0085 15.6 0.0 1.4 2 0 0 2 2 2 1 Retroviral envelope protein Sigma70_ner PF04546.8 KFP04017.1 - 0.089 12.3 0.0 0.089 12.3 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Corona_S2 PF01601.11 KFP04017.1 - 4.4 5.2 14.0 6 4.8 9.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PRK PF00485.13 KFP04018.1 - 8.1e-58 195.1 0.0 9.3e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 KFP04018.1 - 2.6e-07 30.4 0.1 4.2e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 KFP04018.1 - 4.6e-07 30.6 0.1 1e-06 29.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFP04018.1 - 3.5e-06 27.3 0.0 5.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFP04018.1 - 0.0005 19.9 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 KFP04018.1 - 0.0086 15.4 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 1 Dephospho-CoA kinase Zeta_toxin PF06414.7 KFP04018.1 - 0.028 13.5 0.0 0.066 12.3 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KFP04018.1 - 0.049 13.3 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain zf-C2H2_4 PF13894.1 KFP04019.1 - 2.5e-10 39.9 39.3 0.011 15.9 0.5 8.4 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP04019.1 - 1.7e-09 37.5 23.6 0.018 15.1 0.2 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFP04019.1 - 7.6e-09 35.3 45.4 0.0098 16.1 0.5 8.4 8 0 0 8 8 8 4 Zinc finger, C2H2 type CpXC PF14353.1 KFP04019.1 - 9.3e-07 28.8 12.6 0.072 13.0 0.0 4.4 4 0 0 4 4 4 3 CpXC protein zf-BED PF02892.10 KFP04019.1 - 0.00033 20.3 36.4 0.23 11.2 0.4 6.3 4 2 2 6 6 6 4 BED zinc finger DUF629 PF04780.7 KFP04019.1 - 0.00036 19.1 11.3 2.2 6.7 0.0 4.2 4 0 0 4 4 4 4 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 KFP04019.1 - 0.0004 20.4 26.7 0.15 12.2 0.3 6.1 4 2 2 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFP04019.1 - 0.0013 18.8 24.5 0.75 10.0 0.2 5.9 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-FCS PF06467.9 KFP04019.1 - 0.0046 16.5 12.4 0.061 12.9 0.2 4.2 4 0 0 4 4 4 2 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 KFP04019.1 - 0.0047 17.0 23.3 0.19 11.8 0.6 5.4 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFP04019.1 - 0.07 13.0 16.9 3.9 7.5 0.2 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger Evr1_Alr PF04777.8 KFP04019.1 - 7 6.6 12.8 9.5 6.2 0.2 4.1 4 0 0 4 4 4 0 Erv1 / Alr family SAM_2 PF07647.12 KFP04020.1 - 3.3e-17 62.0 0.2 4.7e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP04020.1 - 3.7e-08 33.4 0.1 6.5e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFP04020.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PilI PF10623.4 KFP04020.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI tRNA_NucTran2_2 PF13735.1 KFP04020.1 - 0.062 13.1 0.1 0.098 12.4 0.1 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative PRP1_N PF06424.7 KFP04021.1 - 3.1e-40 137.5 6.7 3.1e-40 137.5 4.6 1.8 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KFP04021.1 - 1e-32 109.5 21.3 0.0013 19.1 0.0 13.7 5 3 9 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 KFP04021.1 - 7.3e-23 80.6 7.2 4.1e-06 27.0 0.1 9.5 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFP04021.1 - 5.8e-20 71.4 17.6 0.0011 19.6 0.0 8.9 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFP04021.1 - 1.4e-10 40.5 2.2 0.084 13.1 0.0 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFP04021.1 - 6e-10 38.2 12.7 0.071 13.0 0.0 10.1 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFP04021.1 - 2.1e-08 33.7 14.8 0.0053 16.3 0.2 7.6 7 3 2 9 9 8 3 TPR repeat TPR_8 PF13181.1 KFP04021.1 - 4.6e-07 29.1 0.2 0.056 13.2 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 KFP04021.1 - 9.1e-07 28.8 3.9 0.048 13.3 0.0 6.0 5 1 1 7 7 7 1 Suppressor of forked protein (Suf) TPR_1 PF00515.23 KFP04021.1 - 2.1e-05 23.9 0.4 0.34 10.5 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP04021.1 - 4.8e-05 23.2 5.7 6 6.8 0.0 6.6 5 1 3 8 8 8 2 Tetratricopeptide repeat OsmC PF02566.14 KFP04021.1 - 0.036 14.2 2.2 13 6.0 0.0 5.1 6 0 0 6 6 6 0 OsmC-like protein TPR_6 PF13174.1 KFP04021.1 - 1.8 9.2 12.4 2.5e+02 2.4 0.0 8.1 13 0 0 13 13 9 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFP04021.1 - 4.6 7.1 12.9 0.22 11.4 0.7 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat RGS PF00615.14 KFP04022.1 - 1.1e-35 122.2 1.0 1.4e-35 121.9 0.7 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_1 PF00001.16 KFP04023.1 - 1.2e-64 217.9 18.0 1.7e-64 217.4 12.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04023.1 - 8.4e-14 51.3 18.9 1.3e-13 50.7 13.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP04023.1 - 3.2e-08 33.0 6.8 3.2e-08 33.0 4.7 2.1 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFP04023.1 - 4.3e-05 22.7 17.5 4.3e-05 22.7 12.1 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Dispanin PF04505.7 KFP04023.1 - 2 7.9 7.6 0.26 10.8 0.1 3.1 4 0 0 4 4 4 0 Interferon-induced transmembrane protein Herpes_US9 PF06072.6 KFP04023.1 - 6.4 6.6 8.3 0.27 11.0 0.5 2.6 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 MYT1 PF08474.6 KFP04024.1 - 4.8e-90 301.5 22.1 8.6e-65 218.7 11.3 4.9 3 2 1 4 4 4 2 Myelin transcription factor 1 zf-C2HC PF01530.13 KFP04024.1 - 7.5e-70 230.2 59.6 6.5e-16 57.7 4.3 6.4 6 0 0 6 6 6 5 Zinc finger, C2HC type DUF1664 PF07889.7 KFP04024.1 - 0.94 9.2 4.3 2.3 8.0 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ly49 PF08391.5 KFP04024.1 - 7.2 6.7 9.5 13 5.9 0.1 2.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region PCMT PF01135.14 KFP04025.1 - 3.6e-26 91.9 0.0 5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SOCS_box PF07525.11 KFP04025.1 - 4.3e-07 29.6 4.7 0.021 14.7 1.7 2.6 2 0 0 2 2 2 2 SOCS box DOT1 PF08123.8 KFP04025.1 - 0.00016 21.0 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 KFP04025.1 - 0.00017 21.1 0.0 0.00038 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP04025.1 - 0.00032 21.2 0.0 0.00081 19.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP04025.1 - 0.0043 17.4 1.8 0.015 15.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain GCD14 PF08704.5 KFP04025.1 - 0.01 15.3 0.6 0.019 14.4 0.0 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit UPF0150 PF03681.10 KFP04025.1 - 0.14 11.8 0.1 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) Pkinase_Tyr PF07714.12 KFP04026.1 - 1.1e-90 303.1 0.0 1.4e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP04026.1 - 1.7e-50 171.6 0.0 2.3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP04026.1 - 3.4e-24 84.4 0.0 7.5e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.1 KFP04026.1 - 1.1e-08 34.5 0.0 2.2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP04026.1 - 9.5e-07 28.1 0.0 1.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain RIO1 PF01163.17 KFP04026.1 - 0.00065 19.1 0.1 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family SH3_2 PF07653.12 KFP04026.1 - 0.0066 15.9 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 KFP04026.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KFP04026.1 - 0.017 14.1 0.2 0.04 12.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GTP_EFTU PF00009.22 KFP04027.1 - 1.2e-57 194.4 0.0 1.7e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFP04027.1 - 1.6e-35 121.2 0.0 4.2e-35 119.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFP04027.1 - 2.1e-17 62.9 2.1 2.3e-17 62.8 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KFP04027.1 - 4e-05 23.1 0.1 0.00014 21.4 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KFP04027.1 - 0.00051 19.9 0.4 0.0015 18.5 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFP04027.1 - 0.024 14.4 0.1 8.6 6.1 0.1 2.5 2 0 0 2 2 2 0 Dynamin family KCNQ_channel PF03520.9 KFP04028.1 - 5.8e-65 218.4 0.0 1.5e-64 217.0 0.0 1.7 1 1 0 1 1 1 1 KCNQ voltage-gated potassium channel KCNQC3-Ank-G_bd PF11956.3 KFP04028.1 - 4.3e-41 139.1 0.7 8.5e-41 138.1 0.5 1.5 1 0 0 1 1 1 1 Ankyrin-G binding motif of KCNQ2-3 Ion_trans PF00520.26 KFP04028.1 - 1.9e-27 95.8 6.7 3.2e-27 95.1 4.6 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KFP04028.1 - 4.3e-13 48.7 3.3 1.2e-12 47.3 2.3 1.7 1 0 0 1 1 1 1 Ion channel Neur_chan_LBD PF02931.18 KFP04029.1 - 5.9e-34 117.1 2.6 9.5e-34 116.4 1.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP04029.1 - 1.6e-28 100.2 0.0 2.8e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DEP PF00610.16 KFP04030.1 - 4.5e-44 148.0 0.6 4.7e-22 77.5 0.1 2.3 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ PF00595.19 KFP04030.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) ArfGap PF01412.13 KFP04031.1 - 1.2e-33 115.3 0.4 1.2e-33 115.3 0.3 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Glyco_hydro_17 PF00332.13 KFP04031.1 - 0.004 16.2 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 zf-piccolo PF05715.8 KFP04031.1 - 0.019 14.9 0.8 0.04 13.9 0.6 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger Ribosomal_L37ae PF01780.14 KFP04031.1 - 0.046 13.6 0.2 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Ribosomal L37ae protein family NKAIN PF05640.9 KFP04032.1 - 2.7e-77 258.3 8.6 5.9e-77 257.1 6.0 1.4 1 1 0 1 1 1 1 Na,K-Atpase Interacting protein DUF1003 PF06210.6 KFP04032.1 - 9.7 6.1 8.2 45 4.0 5.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) BIR PF00653.16 KFP04033.1 - 2e-43 146.6 13.2 3.8e-25 88.1 0.3 3.0 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.1 KFP04033.1 - 7.5e-15 54.3 7.4 7.5e-15 54.3 5.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP04033.1 - 6.5e-06 26.0 9.0 6.5e-06 26.0 6.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP04033.1 - 0.00022 20.8 6.7 0.00022 20.8 4.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFP04033.1 - 0.0014 18.1 2.7 0.0038 16.7 1.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2039 PF10217.4 KFP04033.1 - 0.44 10.5 2.7 0.82 9.7 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_2 PF13639.1 KFP04033.1 - 2.5 7.9 15.7 0.19 11.5 6.2 2.5 2 0 0 2 2 2 0 Ring finger domain YTH PF04146.10 KFP04034.1 - 5.3e-49 165.4 0.1 7.7e-49 164.8 0.1 1.2 1 0 0 1 1 1 1 YT521-B-like domain Yae1_N PF09811.4 KFP04035.1 - 1.5e-20 72.3 56.0 1.5e+04 -18.0 38.8 5.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MFS_1 PF07690.11 KFP04036.1 - 7.2e-45 153.2 28.7 7.2e-45 153.2 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 KFP04036.1 - 0.43 10.9 2.5 0.49 10.8 0.6 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CLTH PF10607.4 KFP04037.1 - 2.9e-36 124.3 6.1 3.8e-36 123.9 4.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KFP04037.1 - 8.4e-13 47.5 0.4 3.1e-11 42.6 0.1 2.6 2 0 0 2 2 2 1 LisH FlaF PF07309.6 KFP04037.1 - 0.016 15.0 1.5 0.032 14.0 1.1 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF TFIIS_M PF07500.9 KFP04038.1 - 3.9e-34 117.1 1.9 1.1e-33 115.7 0.6 2.5 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KFP04038.1 - 3.5e-20 72.6 0.0 1.6e-19 70.5 0.0 2.2 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 KFP04038.1 - 5.8e-12 45.1 8.2 1.4e-11 43.8 5.7 1.7 1 0 0 1 1 1 1 PHD-finger Calici_MSP PF05752.6 KFP04038.1 - 0.043 13.4 5.1 0.072 12.6 0.5 3.1 2 0 0 2 2 2 0 Calicivirus minor structural protein PHD_3 PF13922.1 KFP04038.1 - 1 9.6 4.5 0.53 10.5 0.2 2.9 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx HLH PF00010.21 KFP04039.1 - 5.6e-09 35.5 1.0 2.9e-08 33.2 0.2 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Collagen PF01391.13 KFP04040.1 - 8.3e-18 63.6 57.8 9.1e-10 37.9 21.4 2.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) OGFr_N PF04664.8 KFP04041.1 - 6.1e-93 310.0 11.0 9e-93 309.4 7.6 1.2 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Eaf7 PF07904.8 KFP04042.1 - 7.2e-18 64.3 0.1 1.8e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Asp-B-Hydro_N PF05279.6 KFP04042.1 - 0.025 14.4 4.8 0.029 14.2 3.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RAP1 PF07218.6 KFP04042.1 - 0.58 8.1 4.2 0.7 7.9 2.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vfa1 PF08432.5 KFP04042.1 - 1.4 8.8 7.8 1.9 8.4 5.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 7tm_1 PF00001.16 KFP04043.1 - 3e-12 46.2 13.3 1.2e-11 44.2 9.2 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TraL PF07178.6 KFP04043.1 - 0.18 11.8 5.3 0.072 13.1 0.7 2.3 1 1 1 2 2 2 0 TraL protein OATP PF03137.15 KFP04044.1 - 3e-32 111.3 1.1 3.2e-32 111.3 0.8 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF805 PF05656.9 KFP04044.1 - 0.066 13.0 0.2 0.074 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) GATA PF00320.22 KFP04045.1 - 3.2e-31 106.3 16.2 2e-16 58.9 3.6 2.4 2 0 0 2 2 2 2 GATA zinc finger GATA-N PF05349.7 KFP04045.1 - 2.7e-18 66.7 0.9 2.7e-18 66.7 0.6 2.2 2 0 0 2 2 2 1 GATA-type transcription activator, N-terminal TF_Zn_Ribbon PF08271.7 KFP04045.1 - 0.00012 21.3 9.5 0.036 13.3 2.3 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 KFP04045.1 - 0.0011 18.7 1.4 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 KFP04045.1 - 0.0018 17.8 2.9 0.39 10.3 0.4 2.3 2 0 0 2 2 2 2 Domain found in IF2B/IF5 DUF2387 PF09526.5 KFP04045.1 - 0.026 14.4 5.1 3.9 7.4 0.7 3.0 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 KFP04045.1 - 0.031 14.0 0.2 0.031 14.0 0.2 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFP04045.1 - 0.042 13.8 4.7 1.1 9.2 0.9 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Elf1 PF05129.8 KFP04045.1 - 0.052 13.2 3.9 1.3 8.7 0.0 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 KFP04045.1 - 0.14 11.9 10.1 11 5.9 1.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon BaffR-Tall_bind PF09256.5 KFP04045.1 - 0.19 11.3 4.5 2.1 8.0 0.0 3.2 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding OrfB_Zn_ribbon PF07282.6 KFP04045.1 - 0.38 10.4 7.5 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 KFP04045.1 - 0.89 8.8 9.9 2.1 7.6 0.9 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.7 KFP04045.1 - 1.5 8.9 13.3 0.17 12.0 2.1 3.0 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase Cytochrom_c3_2 PF14537.1 KFP04045.1 - 1.6 9.1 6.8 2.2 8.7 3.9 1.8 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KFP04045.1 - 6.3 6.4 10.6 34 4.1 7.4 2.1 1 1 0 1 1 1 0 Cytochrome c7 CtIP_N PF10482.4 KFP04046.1 - 9.5e-54 180.3 18.2 9.5e-54 180.3 12.6 2.1 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain DivIC PF04977.10 KFP04046.1 - 0.029 13.8 0.9 0.029 13.8 0.6 3.9 5 0 0 5 5 5 0 Septum formation initiator HI0933_like PF03486.9 KFP04046.1 - 1.8 6.9 3.8 3 6.2 2.7 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF342 PF03961.8 KFP04046.1 - 3 6.1 8.1 4.8 5.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 KFP04046.1 - 6.3 7.1 18.9 6 7.2 3.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 KFP04046.1 - 7.2 6.3 18.5 0.47 10.2 2.0 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4618 PF15397.1 KFP04046.1 - 9.7 5.4 21.8 0.31 10.3 1.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Cyclin_N PF00134.18 KFP04047.1 - 3.9e-09 36.1 0.5 6.4e-09 35.4 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain HGTP_anticodon PF03129.15 KFP04047.1 - 0.097 12.6 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Anticodon binding domain Laminin_EGF PF00053.19 KFP04048.1 - 9.5e-157 508.8 440.5 1.7e-11 43.8 9.7 22.8 19 3 3 22 22 22 22 Laminin EGF-like (Domains III and V) Laminin_G_2 PF02210.19 KFP04048.1 - 3.9e-73 243.5 0.0 2.8e-23 82.3 0.0 5.5 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.18 KFP04048.1 - 8.6e-50 168.1 0.0 5.6e-16 58.7 0.0 5.4 5 0 0 5 5 5 5 Laminin G domain Laminin_I PF06008.9 KFP04048.1 - 1.4e-45 155.7 42.4 1.4e-45 155.7 29.4 2.6 1 1 2 3 3 3 1 Laminin Domain I Laminin_N PF00055.12 KFP04048.1 - 1.2e-41 142.3 0.1 4.1e-41 140.5 0.0 2.1 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_II PF06009.7 KFP04048.1 - 9.1e-38 129.1 6.0 9.1e-38 129.1 4.1 5.2 3 1 3 6 6 6 1 Laminin Domain II Laminin_B PF00052.13 KFP04048.1 - 1.9e-22 79.3 0.0 5.3e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Laminin B (Domain IV) Laminin_G_3 PF13385.1 KFP04048.1 - 4.3e-16 59.5 0.2 2.9e-06 27.6 0.0 3.6 3 0 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily Proteasom_Rpn13 PF04683.8 KFP04049.1 - 7.1e-36 122.1 0.1 1.2e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ASXH PF13919.1 KFP04049.1 - 0.0047 16.7 0.0 0.0096 15.7 0.0 1.5 1 1 0 1 1 1 1 Asx homology domain Hamartin PF04388.7 KFP04049.1 - 2.5 6.6 6.0 3.1 6.3 4.1 1.1 1 0 0 1 1 1 0 Hamartin protein Oxysterol_BP PF01237.13 KFP04050.1 - 2.7e-142 473.4 0.1 3.3e-142 473.1 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein 7tm_1 PF00001.16 KFP04051.1 - 3e-47 160.9 7.5 4.4e-47 160.3 5.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GTP1_OBG PF01018.17 KFP04052.1 - 2.2e-41 141.1 7.4 2.8e-41 140.7 5.2 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 KFP04052.1 - 1.2e-21 76.8 0.0 1.7e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP04052.1 - 8.1e-13 47.9 0.0 2.1e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFP04052.1 - 3.7e-05 24.2 0.0 6.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KFP04052.1 - 0.0025 17.6 0.0 0.24 11.2 0.0 2.2 1 1 1 2 2 2 1 Dynamin family Arf PF00025.16 KFP04052.1 - 0.004 16.4 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP04052.1 - 0.0042 16.5 0.0 0.019 14.3 0.0 1.9 1 1 0 1 1 1 1 Ras family Vps4_C PF09336.5 KFP04052.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain SSXT PF05030.7 KFP04053.1 - 1.3e-34 117.5 2.0 2.6e-34 116.6 1.4 1.5 1 0 0 1 1 1 1 SSXT protein (N-terminal region) DUF1313 PF07011.6 KFP04053.1 - 0.081 12.5 1.9 1.9 8.2 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1313) Proteasome PF00227.21 KFP04054.1 - 5.3e-64 215.0 0.2 6.7e-64 214.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFP04054.1 - 5.9e-15 54.2 0.2 1.4e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF4372 PF14294.1 KFP04054.1 - 0.079 12.8 0.2 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) FDF PF09532.5 KFP04055.1 - 3.4e-30 104.6 9.4 7.1e-30 103.6 6.5 1.5 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.2 KFP04055.1 - 1.1e-21 76.4 0.7 1.7e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Scd6-like Sm domain TAF4 PF05236.9 KFP04056.1 - 4.9e-88 294.8 8.9 5.7e-88 294.6 6.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF PF02969.12 KFP04056.1 - 0.0028 17.5 0.3 0.4 10.6 0.0 2.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) SAGA-Tad1 PF12767.2 KFP04056.1 - 0.0053 16.4 0.0 0.0053 16.4 0.0 2.5 1 1 1 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF3141 PF11339.3 KFP04056.1 - 0.15 10.3 4.5 0.18 10.0 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) AAA_23 PF13476.1 KFP04056.1 - 0.37 11.0 5.8 0.57 10.4 4.0 1.4 1 0 0 1 1 1 0 AAA domain FAM217 PF15344.1 KFP04057.1 - 1.6e-85 286.4 3.1 2.1e-85 285.9 2.2 1.2 1 0 0 1 1 1 1 FAM217 family CBM_21 PF03370.8 KFP04059.1 - 9.1e-33 112.6 0.1 1.2e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KFP04059.1 - 0.0084 16.1 1.9 0.052 13.6 1.3 2.1 1 1 0 1 1 1 1 Carbohydrate binding domain (family 25) RPEL PF02755.10 KFP04060.1 - 8.6e-26 88.5 20.6 4.9e-09 35.2 1.9 4.7 4 0 0 4 4 4 4 RPEL repeat Sod_Ni PF09055.6 KFP04060.1 - 4.3 7.7 5.8 1.3 9.4 0.7 2.4 3 0 0 3 3 3 0 Nickel-containing superoxide dismutase Endothelin PF00322.12 KFP04061.1 - 0.0005 19.2 4.5 0.0006 18.9 3.1 1.1 1 0 0 1 1 1 1 Endothelin family Hormone_6 PF00236.13 KFP04063.1 - 0.25 11.1 3.9 3 7.7 0.2 2.8 1 1 2 3 3 3 0 Glycoprotein hormone zf-C2H2 PF00096.21 KFP04064.1 - 3.3e-08 33.3 9.8 0.00031 20.8 0.5 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP04064.1 - 9.8e-08 31.9 0.1 9.8e-08 31.9 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP04064.1 - 9.4e-06 25.6 4.5 0.029 14.5 0.9 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP04064.1 - 0.0045 16.8 0.5 0.0045 16.8 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFP04064.1 - 0.068 13.5 8.8 1.2 9.6 0.6 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KFP04064.1 - 0.98 9.7 11.2 3.6 7.9 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PRELI PF04707.9 KFP04065.1 - 2.9e-57 192.6 0.1 3.4e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family ATP-synt_Eps PF04627.8 KFP04066.1 - 5.9e-14 51.3 1.8 6.1e-14 51.2 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Tubulin PF00091.20 KFP04067.1 - 1.4e-72 244.0 0.0 2e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFP04067.1 - 1.2e-47 161.0 0.0 1.9e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFP04067.1 - 4.6e-05 23.4 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFP04067.1 - 0.0049 16.3 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Peptidase_C1 PF00112.18 KFP04068.1 - 1.1e-50 172.5 13.3 1.3e-50 172.2 9.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFP04068.1 - 0.079 11.4 0.7 0.22 10.0 0.6 1.5 2 0 0 2 2 2 0 Peptidase C1-like family TH1 PF04858.8 KFP04069.1 - 3.2e-291 966.6 0.4 3.6e-291 966.5 0.3 1.0 1 0 0 1 1 1 1 TH1 protein G-alpha PF00503.15 KFP04070.1 - 2.1e-107 359.2 1.3 2.3e-107 359.0 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP04070.1 - 1.6e-14 53.5 1.5 1.2e-13 50.7 0.4 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KFP04070.1 - 5.6e-05 23.6 0.3 0.042 14.3 0.1 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KFP04070.1 - 0.0017 17.5 0.4 0.0017 17.5 0.3 2.0 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP04070.1 - 0.012 15.0 0.4 0.58 9.5 0.0 2.4 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M17 PF00883.16 KFP04071.1 - 1.6e-93 313.0 0.0 2e-93 312.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain APCDDC PF14921.1 KFP04072.1 - 1.1e-119 398.1 0.1 6.4e-89 297.4 0.0 2.1 1 1 1 2 2 2 2 Adenomatosis polyposis coli down-regulated 1 Motile_Sperm PF00635.21 KFP04073.1 - 1.7e-30 104.8 0.1 3.3e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF904 PF06005.7 KFP04073.1 - 0.0037 17.5 0.2 0.0055 16.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF964 PF06133.6 KFP04073.1 - 0.029 14.3 0.4 0.049 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF972 PF06156.8 KFP04073.1 - 0.039 14.2 0.2 0.06 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IF2_N PF04760.10 KFP04073.1 - 0.061 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region NUDE_C PF04880.8 KFP04073.1 - 0.23 11.8 6.8 0.14 12.5 1.3 2.3 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Ras PF00071.17 KFP04074.1 - 5e-56 188.5 0.0 5.7e-56 188.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP04074.1 - 2.1e-20 73.3 0.0 3.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP04074.1 - 1.6e-14 53.5 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP04074.1 - 3.8e-06 26.2 0.0 4.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP04074.1 - 1.7e-05 24.3 0.1 5.8e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP04074.1 - 4.8e-05 23.2 0.0 6.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFP04074.1 - 0.00043 20.3 0.0 0.0058 16.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KFP04074.1 - 0.024 13.8 0.0 0.083 12.0 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 CNTF PF01110.12 KFP04074.1 - 0.047 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor AAA_24 PF13479.1 KFP04074.1 - 0.079 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFP04074.1 - 0.098 12.3 0.0 0.17 11.6 0.0 1.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) F_actin_cap_B PF01115.12 KFP04074.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit DIT1_PvcA PF05141.7 KFP04074.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein HEAT PF02985.17 KFP04075.1 - 2.3e-23 80.1 19.3 0.012 15.6 0.0 10.8 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.1 KFP04075.1 - 6.7e-13 48.7 0.2 0.00098 19.3 0.0 6.3 3 2 2 5 5 5 3 HEAT repeats AF1Q PF15017.1 KFP04075.1 - 1.1e-06 28.4 0.1 1.1e-06 28.4 0.1 2.3 3 0 0 3 3 3 1 Drug resistance and apoptosis regulator Vac14_Fab1_bd PF12755.2 KFP04075.1 - 0.00062 20.1 1.8 1.8 9.0 0.0 5.0 4 3 1 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFP04075.1 - 0.013 15.9 1.3 27 5.4 0.1 4.9 6 0 0 6 6 6 0 HEAT-like repeat Ank_2 PF12796.2 KFP04076.1 - 1.5e-28 98.9 0.6 1.3e-14 54.2 0.1 1.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP04076.1 - 6.9e-15 54.0 0.1 2.2e-06 27.1 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFP04076.1 - 6.8e-12 45.2 2.5 3.3e-07 30.3 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP04076.1 - 1.1e-10 41.7 0.9 1.8e-09 37.8 0.3 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP04076.1 - 1.3e-10 40.3 1.6 7.6e-05 22.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ubiquitin_2 PF14560.1 KFP04076.1 - 3.9e-05 23.8 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KFP04076.1 - 0.01 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family LLC1 PF14945.1 KFP04077.1 - 5.2e-28 97.8 0.8 6.3e-28 97.5 0.5 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Shisa PF13908.1 KFP04078.1 - 0.96 9.5 3.5 0.33 11.1 0.5 1.7 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator PEPCK PF00821.13 KFP04079.1 - 3.9e-281 933.4 0.0 4.4e-281 933.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase zf-H2C2_2 PF13465.1 KFP04080.1 - 1.1e-38 129.5 66.0 1.4e-08 34.5 1.1 8.2 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04080.1 - 2.3e-18 65.3 74.4 0.00011 22.3 0.4 8.8 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04080.1 - 1.7e-10 40.4 65.6 0.0042 17.3 0.3 8.6 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP04080.1 - 3.4e-09 36.3 15.6 0.00011 22.1 0.1 9.7 9 2 0 9 9 9 3 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFP04080.1 - 0.00015 21.7 46.1 0.056 13.6 1.8 7.4 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP04080.1 - 0.015 15.2 2.7 0.015 15.2 1.9 8.3 9 1 0 9 9 9 0 C2H2-type zinc finger GAGA PF09237.6 KFP04080.1 - 0.029 13.9 9.0 5.8 6.5 0.0 4.7 1 1 4 5 5 5 0 GAGA factor zf-met PF12874.2 KFP04080.1 - 0.071 13.3 0.5 0.071 13.3 0.4 6.9 7 1 0 7 7 7 0 Zinc-finger of C2H2 type C1_1 PF00130.17 KFP04080.1 - 0.1 12.3 38.5 0.17 11.6 2.4 5.3 3 1 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_2 PF12756.2 KFP04080.1 - 0.34 11.0 42.0 0.72 10.0 8.7 5.6 1 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Pox_A3L PF05288.6 KFP04080.1 - 0.73 9.6 6.4 1.6 8.5 0.5 4.0 4 0 0 4 4 4 0 Poxvirus A3L Protein WD40 PF00400.27 KFP04082.1 - 6.7e-24 82.8 15.2 8e-07 28.7 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 KFP04082.1 - 0.053 11.6 0.4 0.33 9.0 0.3 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 ARGLU PF15346.1 KFP04083.1 - 8.2 6.1 42.0 13 5.5 13.2 2.1 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 TP6A_N PF04406.9 KFP04084.1 - 2.7e-23 81.4 0.2 4.9e-23 80.5 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Chitin_bind_4 PF00379.18 KFP04084.1 - 0.061 13.6 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Insect cuticle protein DUF760 PF05542.6 KFP04084.1 - 0.089 12.9 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF760) TGFb_propeptide PF00688.13 KFP04085.1 - 6.4e-45 153.3 0.0 9.3e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFP04085.1 - 5.1e-44 148.8 1.3 1.1e-43 147.8 0.9 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TF_AP-2 PF03299.9 KFP04086.1 - 2.9e-99 330.8 0.0 4.1e-99 330.3 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 Rtf2 PF04641.7 KFP04087.1 - 1.8e-80 269.9 9.5 2.3e-80 269.5 6.6 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Branch PF02485.16 KFP04088.1 - 4.3e-50 170.1 1.2 5e-50 169.9 0.2 1.5 2 0 0 2 2 2 1 Core-2/I-Branching enzyme WD40 PF00400.27 KFP04089.1 - 1.3e-37 126.3 9.2 2.4e-10 39.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF3312 PF11768.3 KFP04089.1 - 2.7e-05 22.6 0.1 0.00016 20.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Pkinase PF00069.20 KFP04090.1 - 2.9e-64 216.7 0.3 5.3e-64 215.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04090.1 - 1.6e-38 132.2 0.1 3e-38 131.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP04090.1 - 0.00013 20.9 0.0 0.00061 18.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP04090.1 - 0.0081 15.9 0.0 0.031 14.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP04090.1 - 0.024 13.9 0.0 0.024 13.9 0.0 1.9 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KFP04090.1 - 0.053 12.3 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RR_TM4-6 PF06459.7 KFP04090.1 - 0.16 11.8 6.8 0.22 11.3 4.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 KFP04090.1 - 3.4 6.5 12.3 4.8 6.0 8.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ndc1_Nup PF09531.5 KFP04090.1 - 5.5 5.2 7.6 7.1 4.9 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PBP_sp32 PF07222.7 KFP04090.1 - 7.2 5.7 11.0 11 5.0 7.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1279 PF06916.8 KFP04091.1 - 5.6e-28 97.0 0.9 6.5e-28 96.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) YiaAB PF05360.9 KFP04091.1 - 4.4 6.9 5.9 0.79 9.3 1.1 1.9 2 1 0 2 2 2 0 yiaA/B two helix domain 7tm_1 PF00001.16 KFP04092.1 - 5.1e-42 143.7 36.8 2.5e-40 138.2 25.5 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04092.1 - 1.9e-06 27.2 38.0 4e-06 26.1 26.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP04092.1 - 6.8 5.7 42.9 0.071 12.2 18.4 2.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx C1q PF00386.16 KFP04093.1 - 1.5e-19 70.2 0.3 1.6e-19 70.1 0.2 1.0 1 0 0 1 1 1 1 C1q domain Glyco_hydro_71 PF03659.9 KFP04093.1 - 0.042 12.3 0.0 0.042 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Prefoldin_2 PF01920.15 KFP04094.1 - 6.3e-26 90.1 10.4 7.3e-26 90.0 7.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.7 KFP04094.1 - 0.00013 22.1 6.6 0.0069 16.6 0.7 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 KFP04094.1 - 0.00042 20.0 4.8 0.00069 19.3 3.4 1.4 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 KFP04094.1 - 0.00064 19.7 4.1 0.00095 19.2 2.8 1.3 1 0 0 1 1 1 1 DivIVA protein Prefoldin PF02996.12 KFP04094.1 - 0.0017 17.9 9.3 0.24 11.0 6.4 2.1 1 1 0 1 1 1 1 Prefoldin subunit Mnd1 PF03962.10 KFP04094.1 - 0.0039 16.8 3.3 0.0054 16.4 2.3 1.2 1 0 0 1 1 1 1 Mnd1 family FliD_C PF07195.7 KFP04094.1 - 0.0042 16.4 3.4 0.0072 15.6 0.1 2.0 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus FlxA PF14282.1 KFP04094.1 - 0.0043 16.9 8.5 0.41 10.6 0.3 2.2 2 0 0 2 2 2 2 FlxA-like protein Fib_alpha PF08702.5 KFP04094.1 - 0.0057 16.7 6.0 0.52 10.4 0.3 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family YlbD_coat PF14071.1 KFP04094.1 - 0.0073 16.3 1.1 0.062 13.3 0.8 2.1 1 1 0 1 1 1 1 Putative coat protein TBCA PF02970.11 KFP04094.1 - 0.011 15.8 7.1 0.032 14.3 0.6 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A Mod_r PF07200.8 KFP04094.1 - 0.011 15.6 5.5 0.48 10.3 0.6 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.1 KFP04094.1 - 0.012 15.5 8.0 0.6 10.0 0.4 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Med9 PF07544.8 KFP04094.1 - 0.012 15.3 14.1 0.25 11.0 2.7 3.0 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 KFP04094.1 - 0.013 15.1 8.7 0.068 12.7 1.3 2.0 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 KFP04094.1 - 0.014 14.8 6.2 0.66 9.4 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.17 KFP04094.1 - 0.014 15.3 6.9 0.95 9.5 0.7 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FTA4 PF13093.1 KFP04094.1 - 0.016 14.6 3.3 0.021 14.2 2.3 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GvpL_GvpF PF06386.6 KFP04094.1 - 0.017 14.7 1.4 0.05 13.1 0.5 1.8 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF CCDC-167 PF15188.1 KFP04094.1 - 0.019 14.8 5.5 0.034 14.0 0.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.7 KFP04094.1 - 0.022 14.5 5.9 0.032 14.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lzipper-MIP1 PF14389.1 KFP04094.1 - 0.033 14.2 6.6 0.12 12.5 1.0 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Kinesin-relat_1 PF12711.2 KFP04094.1 - 0.035 14.4 6.8 0.051 13.9 1.0 2.2 2 0 0 2 2 2 0 Kinesin motor RraB PF06877.6 KFP04094.1 - 0.039 14.5 2.9 0.29 11.8 0.4 2.3 1 1 1 2 2 2 0 Regulator of ribonuclease activity B DUF4200 PF13863.1 KFP04094.1 - 0.04 13.8 9.8 0.91 9.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Glyco_hydro_4C PF11975.3 KFP04094.1 - 0.041 13.6 0.6 0.06 13.1 0.4 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Syntaxin-6_N PF09177.6 KFP04094.1 - 0.043 14.2 3.4 0.54 10.6 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Acyl-CoA_dh_C PF12806.2 KFP04094.1 - 0.043 13.6 0.7 3.3 7.5 0.1 2.1 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like GP41 PF00517.12 KFP04094.1 - 0.047 13.2 5.4 0.18 11.3 0.3 2.0 2 0 0 2 2 2 0 Retroviral envelope protein Atg14 PF10186.4 KFP04094.1 - 0.049 12.5 5.5 1.2 7.9 0.2 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Activator-TraM PF11657.3 KFP04094.1 - 0.057 12.9 1.6 0.076 12.4 0.5 1.6 1 1 0 1 1 1 0 Transcriptional activator TraM ATG16 PF08614.6 KFP04094.1 - 0.06 13.1 10.0 0.47 10.2 1.0 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) XhlA PF10779.4 KFP04094.1 - 0.062 13.2 6.8 0.22 11.4 0.3 2.3 2 0 0 2 2 2 0 Haemolysin XhlA KxDL PF10241.4 KFP04094.1 - 0.066 13.1 2.2 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein AAA_23 PF13476.1 KFP04094.1 - 0.068 13.4 7.5 0.092 13.0 5.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KFP04094.1 - 0.069 11.8 3.8 0.084 11.5 2.6 1.1 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 KFP04094.1 - 0.076 12.5 6.7 0.78 9.2 0.7 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlgN PF05130.7 KFP04094.1 - 0.088 13.0 3.7 0.13 12.5 2.5 1.2 1 0 0 1 1 1 0 FlgN protein TMF_DNA_bd PF12329.3 KFP04094.1 - 0.092 12.5 13.4 1.1 9.1 0.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AATF-Che1 PF13339.1 KFP04094.1 - 0.1 12.7 4.5 0.18 11.9 0.6 2.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor CENP-F_leu_zip PF10473.4 KFP04094.1 - 0.12 12.2 11.9 0.12 12.2 2.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 KFP04094.1 - 0.14 11.9 12.7 0.31 10.8 3.3 2.1 2 0 0 2 2 2 0 Tropomyosin like Ax_dynein_light PF10211.4 KFP04094.1 - 0.16 11.7 8.4 0.5 10.1 1.1 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF848 PF05852.6 KFP04094.1 - 0.17 11.6 6.1 2.9 7.7 0.6 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DASH_Dam1 PF08653.5 KFP04094.1 - 0.2 11.4 1.2 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 Sec2p PF06428.6 KFP04094.1 - 0.2 11.4 8.0 0.59 10.0 1.1 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Bacillus_HBL PF05791.6 KFP04094.1 - 0.2 10.9 4.8 0.27 10.5 0.3 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.3 KFP04094.1 - 0.21 11.4 8.1 0.44 10.4 1.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KFP04094.1 - 0.22 11.9 8.1 0.64 10.4 1.1 2.1 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3450 PF11932.3 KFP04094.1 - 0.28 10.4 5.9 0.74 9.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1732 PF08340.6 KFP04094.1 - 0.29 10.9 5.7 4 7.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) AAA_27 PF13514.1 KFP04094.1 - 0.29 8.7 6.6 2.1 5.9 0.5 1.8 1 1 0 2 2 2 0 AAA domain Bap31 PF05529.7 KFP04094.1 - 0.29 10.5 7.5 1.2 8.5 0.6 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4164 PF13747.1 KFP04094.1 - 0.35 11.0 4.5 1.9 8.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Occludin_ELL PF07303.8 KFP04094.1 - 0.35 11.6 4.9 5.5 7.7 0.3 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF972 PF06156.8 KFP04094.1 - 0.37 11.1 7.2 0.24 11.7 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GrpE PF01025.14 KFP04094.1 - 0.37 10.3 6.3 1.6 8.2 0.5 2.1 2 0 0 2 2 2 0 GrpE CHD5 PF04420.9 KFP04094.1 - 0.44 10.2 3.2 1.6 8.3 0.2 2.1 2 0 0 2 2 2 0 CHD5-like protein DUF2205 PF10224.4 KFP04094.1 - 0.61 9.6 5.6 0.19 11.3 0.8 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) IATP PF04568.7 KFP04094.1 - 0.65 10.0 7.9 4.2 7.4 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP SlyX PF04102.7 KFP04094.1 - 0.71 10.2 5.6 6.7 7.1 0.7 2.5 2 0 0 2 2 2 0 SlyX PspB PF06667.7 KFP04094.1 - 0.72 9.8 4.8 1.6 8.7 0.4 2.5 2 1 0 2 2 2 0 Phage shock protein B DUF342 PF03961.8 KFP04094.1 - 0.74 8.1 7.3 1.1 7.5 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 KFP04094.1 - 0.8 9.4 11.5 3.8 7.2 1.9 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fmp27_WPPW PF10359.4 KFP04094.1 - 0.82 8.0 7.3 2.4 6.4 5.1 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PCRF PF03462.13 KFP04094.1 - 0.86 9.3 6.0 0.91 9.2 0.4 2.1 2 0 0 2 2 2 0 PCRF domain Med4 PF10018.4 KFP04094.1 - 0.97 8.7 9.1 1.2 8.4 1.1 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 HSCB_C PF07743.8 KFP04094.1 - 1.1 9.7 9.2 3.3 8.2 2.0 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain OmpH PF03938.9 KFP04094.1 - 1.3 8.9 8.0 2.6 7.9 5.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DP PF08781.5 KFP04094.1 - 1.3 8.7 6.8 0.94 9.1 0.3 2.3 2 0 0 2 2 2 0 Transcription factor DP Vfa1 PF08432.5 KFP04094.1 - 1.4 8.9 6.0 5 7.1 4.1 1.7 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4071 PF13281.1 KFP04094.1 - 1.4 7.6 6.5 0.77 8.5 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) DUF1978 PF09321.5 KFP04094.1 - 1.4 8.2 10.4 0.51 9.7 1.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) P4Ha_N PF08336.6 KFP04094.1 - 1.6 8.5 5.8 3.3 7.5 0.6 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UPF0449 PF15136.1 KFP04094.1 - 1.7 8.8 5.4 6.3 7.0 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Syntaxin PF00804.20 KFP04094.1 - 1.7 8.8 9.9 3.3 7.9 6.9 1.4 1 1 0 1 1 1 0 Syntaxin Uds1 PF15456.1 KFP04094.1 - 2.3 8.2 8.1 25 4.8 5.3 2.1 1 1 0 1 1 1 0 Up-regulated During Septation DUF2508 PF10704.4 KFP04094.1 - 2.4 8.3 5.6 8 6.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Ubiquitin_2 PF14560.1 KFP04094.1 - 2.4 8.4 7.2 14 6.0 1.1 2.9 1 1 1 2 2 2 0 Ubiquitin-like domain CENP-Q PF13094.1 KFP04094.1 - 2.5 8.1 10.4 5.6 6.9 7.0 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HalX PF08663.5 KFP04094.1 - 2.6 8.1 7.1 2 8.4 0.5 2.5 2 1 0 2 2 2 0 HalX domain FlaC_arch PF05377.6 KFP04094.1 - 3 7.8 9.5 7.4 6.5 0.7 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 KFP04094.1 - 3.1 7.8 9.5 6.5 6.7 2.0 2.3 2 0 0 2 2 2 0 bZIP transcription factor Fzo_mitofusin PF04799.8 KFP04094.1 - 5.3 6.3 9.4 1.8 7.9 1.3 2.1 1 1 1 2 2 2 0 fzo-like conserved region YlqD PF11068.3 KFP04094.1 - 9.8 6.2 11.9 10 6.1 1.1 2.1 1 1 1 2 2 2 0 YlqD protein p450 PF00067.17 KFP04095.1 - 7.1e-89 298.4 0.2 8e-89 298.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Actin PF00022.14 KFP04095.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Actin Tricorn_C1 PF14684.1 KFP04095.1 - 0.12 12.3 0.2 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Tricorn protease C1 domain zf-C2H2 PF00096.21 KFP04096.1 - 1.6e-20 72.1 52.8 6.4e-05 23.0 0.7 9.3 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04096.1 - 2e-13 49.6 54.9 0.03 14.6 1.0 9.0 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP04096.1 - 4.4e-11 42.5 62.6 3.9e-08 33.1 0.2 11.9 13 0 0 13 13 13 5 Zinc-finger double domain zf-C2H2_2 PF12756.2 KFP04096.1 - 0.00029 20.8 1.8 0.00029 20.8 1.3 6.9 4 2 1 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFP04096.1 - 0.026 14.6 28.5 0.15 12.1 0.1 6.3 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFP04096.1 - 0.13 12.5 53.6 0.27 11.5 2.4 9.1 9 0 0 9 9 9 0 C2H2-type zinc-finger domain zinc_ribbon_4 PF13717.1 KFP04096.1 - 1.2 8.9 5.4 14 5.4 0.2 3.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 KFP04096.1 - 2.1 8.1 16.1 0.92 9.2 0.6 5.5 5 1 0 5 5 5 0 zinc-finger of a C2HC-type GATA PF00320.22 KFP04096.1 - 2.6 7.4 8.3 11 5.4 0.3 3.8 3 0 0 3 3 3 0 GATA zinc finger GAGA PF09237.6 KFP04096.1 - 3.3 7.3 6.6 1.4 8.5 0.1 3.0 3 0 0 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.2 KFP04098.1 - 1.3e-09 38.0 26.7 0.0039 17.2 0.2 4.7 3 1 1 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KFP04098.1 - 1.5e-06 28.0 22.8 0.18 12.2 0.5 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP04098.1 - 0.00028 20.6 22.1 0.61 10.0 0.2 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP04098.1 - 0.00082 19.5 34.5 0.21 12.0 0.6 6.0 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-met PF12874.2 KFP04098.1 - 0.0009 19.3 10.0 0.31 11.3 0.2 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP04098.1 - 0.076 13.1 0.2 0.076 13.1 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF678 PF05077.7 KFP04098.1 - 1 9.3 11.8 0.99 9.4 0.1 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF678) Hydrolase PF00702.21 KFP04099.1 - 1.1e-18 68.4 0.0 2.8e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFP04099.1 - 1.4e-18 66.7 0.1 3.8e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFP04099.1 - 7.1e-13 49.1 0.2 2e-12 47.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP04099.1 - 1.1e-05 25.2 0.0 4.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFP04099.1 - 0.003 17.1 0.0 0.012 15.1 0.0 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase GNVR PF13807.1 KFP04099.1 - 0.058 13.1 0.1 0.23 11.2 0.1 2.0 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase RHD PF00554.17 KFP04100.1 - 1.5e-22 80.0 0.5 4.8e-22 78.4 0.4 1.8 1 1 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 KFP04100.1 - 6.8e-06 25.9 0.0 3.7e-05 23.6 0.0 2.3 1 0 0 1 1 1 1 IPT/TIG domain Ion_trans PF00520.26 KFP04101.1 - 9.4e-29 100.0 6.1 4e-28 98.0 4.7 1.6 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP04101.1 - 3.7e-27 94.3 0.0 8.4e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP04101.1 - 8.1e-14 51.0 3.2 8.1e-14 51.0 2.2 2.0 2 0 0 2 2 2 1 Ion channel MoeZ_MoeB PF05237.8 KFP04102.1 - 4.4e-31 106.3 0.1 8.1e-31 105.4 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain ThiF PF00899.16 KFP04102.1 - 1.3e-14 54.1 0.0 2.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.15 KFP04102.1 - 4.4e-11 43.1 0.0 1.1e-10 41.8 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Glycos_transf_2 PF00535.21 KFP04103.1 - 1.2e-32 112.9 0.0 1.4e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFP04103.1 - 3.5e-10 40.0 0.0 2.1e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFP04103.1 - 2.3e-07 30.2 0.0 3.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFP04103.1 - 9.4e-06 25.0 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KFP04103.1 - 0.04 14.2 0.0 0.078 13.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 Homeobox PF00046.24 KFP04104.1 - 1.9e-07 30.5 0.5 4.8e-07 29.2 0.3 1.7 1 0 0 1 1 1 1 Homeobox domain zf-H2C2_5 PF13909.1 KFP04104.1 - 9.1e-05 22.4 0.5 9.1e-05 22.4 0.3 7.2 8 0 0 8 8 8 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 KFP04104.1 - 0.00055 20.0 45.0 0.021 15.1 0.1 8.7 8 0 0 8 8 8 3 C2H2-type zinc finger Homeobox_KN PF05920.6 KFP04104.1 - 0.0087 15.7 0.3 0.024 14.3 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.21 KFP04104.1 - 0.082 13.2 0.3 0.082 13.2 0.2 7.4 8 0 0 8 8 8 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 KFP04104.1 - 0.12 12.4 0.2 0.12 12.4 0.1 7.3 7 2 1 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFP04104.1 - 4 7.7 9.8 13 6.0 0.0 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP04104.1 - 5.5 7.1 32.5 0.068 13.2 4.5 6.8 4 4 3 7 7 7 0 C2H2 type zinc-finger (2 copies) PB1 PF00564.19 KFP04105.1 - 1e-12 47.5 0.0 1.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.19 KFP04105.1 - 1.8e-11 44.0 0.0 3.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP04105.1 - 0.042 13.7 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain CENP-F_leu_zip PF10473.4 KFP04106.1 - 0.00013 21.8 30.3 0.00013 21.8 21.0 7.6 1 1 8 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 KFP04106.1 - 0.00013 21.6 19.0 0.00013 21.6 13.2 12.2 3 3 9 12 12 12 4 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KFP04106.1 - 0.0018 17.5 3.7 0.0018 17.5 2.5 5.5 1 1 5 6 6 6 4 Reovirus sigma C capsid protein ATG16 PF08614.6 KFP04106.1 - 0.0041 16.9 33.5 0.0041 16.9 23.2 8.0 1 1 6 7 7 7 2 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 KFP04106.1 - 0.0068 16.2 6.6 0.0068 16.2 4.5 8.4 1 1 5 8 8 8 1 Protein of unknown function (DUF1664) Y_phosphatase PF00102.22 KFP04107.1 - 3.9e-81 271.8 0.0 5.5e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP04107.1 - 5.2e-05 22.8 0.0 9.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP04107.1 - 0.019 15.2 0.1 0.07 13.3 0.0 1.9 1 1 1 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP04107.1 - 0.026 14.5 0.9 0.065 13.2 0.1 2.2 2 1 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.7 KFP04107.1 - 0.13 11.7 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Serinc PF03348.10 KFP04108.1 - 5.2e-178 592.1 15.5 5.9e-178 591.9 10.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2530 PF10745.4 KFP04108.1 - 7.6 6.5 11.3 0.78 9.7 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) CRAL_TRIO PF00650.15 KFP04109.1 - 2.2e-33 115.0 0.0 3.2e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFP04109.1 - 2.8e-11 43.3 0.3 8.1e-11 41.8 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFP04109.1 - 8.8e-06 25.6 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Hormone_recep PF00104.25 KFP04110.1 - 1.4e-38 132.0 0.0 2.1e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP04110.1 - 3e-30 104.2 18.3 4.8e-30 103.5 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Foamy_virus_ENV PF03408.9 KFP04110.1 - 0.014 12.9 0.8 0.019 12.5 0.6 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein CAP PF00188.21 KFP04111.1 - 8.6e-21 74.7 4.2 1.1e-20 74.3 2.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Myticin-prepro PF10690.4 KFP04111.1 - 0.81 9.7 4.9 1.6 8.8 3.4 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Scs3p PF10261.4 KFP04112.1 - 1.1e-41 142.4 12.7 2.1e-41 141.5 8.8 1.4 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 KFP04112.1 - 0.00095 18.8 2.6 0.00095 18.8 1.8 2.3 1 1 1 2 2 2 1 PAP2 superfamily ARL6IP6 PF15062.1 KFP04112.1 - 0.034 14.0 0.4 0.034 14.0 0.3 2.4 2 1 1 3 3 3 0 Haemopoietic lineage transmembrane helix GST_N_3 PF13417.1 KFP04113.1 - 5.3e-08 32.9 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFP04113.1 - 2.5e-07 30.5 0.0 5.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFP04113.1 - 7.1e-06 26.1 0.0 1.9e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFP04113.1 - 5e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFP04113.1 - 0.00063 19.6 0.1 0.0013 18.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4208 PF13907.1 KFP04113.1 - 0.018 15.2 0.7 0.055 13.6 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) GST_C_3 PF14497.1 KFP04113.1 - 0.071 13.5 0.0 0.15 12.5 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF776 PF05604.6 KFP04114.1 - 5.9e-46 156.9 10.3 2.4e-45 154.9 4.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF776) DUF776 PF05604.6 KFP04115.1 - 2.6e-53 180.8 15.4 3e-53 180.6 8.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF776) CHDCT2 PF08074.6 KFP04115.1 - 0.074 12.7 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain MORN PF02493.15 KFP04116.1 - 1.2e-34 115.9 68.1 6.9e-07 28.6 2.2 8.7 9 0 0 9 9 9 8 MORN repeat 7tm_1 PF00001.16 KFP04118.1 - 6.6e-52 176.1 23.8 8.1e-52 175.8 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04118.1 - 1.7e-07 30.6 20.6 7.3e-07 28.6 14.3 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFP04118.1 - 3e-06 26.5 19.6 1.1e-05 24.7 13.6 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.4 KFP04118.1 - 0.34 9.9 22.7 0.022 13.8 10.2 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DC_STAMP PF07782.8 KFP04119.1 - 1e-30 106.7 0.1 2.4e-30 105.5 0.1 1.7 1 0 0 1 1 1 1 DC-STAMP-like protein MnhB PF04039.8 KFP04119.1 - 3.5 7.7 8.9 6.4 6.8 0.2 2.9 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Na_sulph_symp PF00939.14 KFP04120.1 - 3e-98 329.7 15.1 2.4e-94 316.8 4.7 2.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFP04120.1 - 2e-13 49.6 23.9 1.9e-05 23.4 6.6 3.2 2 1 1 3 3 3 3 Citrate transporter DNA_III_psi PF03603.8 KFP04120.1 - 0.021 14.7 0.2 0.042 13.7 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III psi subunit DUF2098 PF09871.4 KFP04120.1 - 1 9.3 5.3 1.8 8.5 3.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Kdo PF06293.9 KFP04121.1 - 1.6e-07 30.6 0.0 1.8e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFP04121.1 - 9.3e-06 24.9 0.1 1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFP04121.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFP04121.1 - 0.0045 16.3 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 KFP04121.1 - 0.0065 15.6 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 KFP04121.1 - 0.021 13.9 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KFP04121.1 - 0.045 12.5 0.9 1.6 7.5 0.1 2.0 1 1 1 2 2 2 0 Seadornavirus VP7 Sugar_tr PF00083.19 KFP04122.1 - 6.5e-88 295.2 28.3 3.5e-64 217.0 9.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFP04122.1 - 1.9e-28 99.1 44.2 1e-21 77.0 19.1 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 KFP04122.1 - 0.011 15.4 4.9 1 9.2 0.2 3.1 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 KFP04122.1 - 0.019 13.0 14.4 0.014 13.5 2.0 2.4 2 0 0 2 2 2 0 Transmembrane secretion effector Presenilin PF01080.12 KFP04123.1 - 0.032 13.0 0.3 0.049 12.4 0.2 1.2 1 0 0 1 1 1 0 Presenilin DUF3544 PF12064.3 KFP04124.1 - 2e-105 351.1 20.5 2e-105 351.1 14.2 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3544) Bromodomain PF00439.20 KFP04124.1 - 3.9e-16 58.7 0.0 1.4e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.12 KFP04124.1 - 2.8e-10 40.2 0.4 1.4e-09 38.0 0.3 2.3 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 KFP04124.1 - 9.4e-08 31.6 12.8 9.4e-08 31.6 8.9 3.7 3 0 0 3 3 3 1 PHD-finger DUF1640 PF07798.6 KFP04124.1 - 3.7e-05 23.8 6.4 6.3e-05 23.0 2.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) zf-MYND PF01753.13 KFP04124.1 - 0.00014 21.6 17.0 0.00014 21.6 11.8 4.0 3 1 0 3 3 3 1 MYND finger Sulfatase PF00884.18 KFP04125.1 - 3.8e-48 164.2 1.4 5.9e-48 163.6 1.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.3 KFP04125.1 - 1.1e-46 158.7 1.4 3e-46 157.3 1.0 1.8 1 0 0 1 1 1 1 Sulfatase protein Phosphodiest PF01663.17 KFP04125.1 - 0.00041 19.8 3.0 0.00041 19.8 2.1 1.9 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFP04125.1 - 0.032 13.6 0.0 0.095 12.0 0.0 1.8 1 1 0 1 1 1 0 Metalloenzyme superfamily DEP PF00610.16 KFP04126.1 - 3.4e-39 132.4 0.2 5.1e-20 70.9 0.0 3.2 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGEF PF00621.15 KFP04126.1 - 3.7e-38 131.2 2.8 9.5e-38 129.8 0.1 2.9 3 0 0 3 3 3 1 RhoGEF domain PDZ PF00595.19 KFP04126.1 - 2.1e-08 34.1 0.0 0.0037 17.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PH PF00169.24 KFP04126.1 - 5.5e-07 29.7 0.8 3.6e-06 27.1 0.1 2.8 3 0 0 3 3 3 1 PH domain PH_10 PF15411.1 KFP04126.1 - 0.00079 19.6 2.4 0.0019 18.3 0.1 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PDZ_2 PF13180.1 KFP04126.1 - 0.002 17.9 0.0 3.2 7.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain UPF1_Zn_bind PF09416.5 KFP04126.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) Sec7 PF01369.15 KFP04127.1 - 4.6e-69 231.9 2.9 6e-69 231.5 0.8 2.2 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KFP04127.1 - 4.1e-57 192.2 2.4 2.2e-56 189.9 1.6 2.4 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFP04127.1 - 1e-30 105.0 0.2 1e-30 105.0 0.1 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) ATP13 PF12921.2 KFP04127.1 - 0.023 14.0 0.7 0.12 11.7 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase expression CAS_CSE1 PF03378.10 KFP04128.1 - 5.7e-197 654.2 7.6 3.6e-196 651.6 4.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KFP04128.1 - 1.9e-167 556.4 5.3 4e-167 555.4 3.7 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KFP04128.1 - 2.1e-11 43.5 0.2 1.3e-10 41.0 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFP04128.1 - 0.00068 19.5 7.7 0.0036 17.2 0.0 4.2 2 2 1 4 4 4 1 Exportin 1-like protein PUF PF00806.14 KFP04128.1 - 0.045 13.2 0.1 0.96 9.0 0.0 3.1 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Arm PF00514.18 KFP04128.1 - 0.052 13.3 2.6 11 6.0 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP04128.1 - 0.069 13.4 0.3 36 4.7 0.0 3.6 2 1 1 3 3 3 0 HEAT repeats dsrm PF00035.20 KFP04129.1 - 6.9e-51 170.6 3.9 1.8e-12 47.6 0.0 5.1 5 0 0 5 5 5 4 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFP04129.1 - 6.8e-10 39.0 2.0 0.0017 18.5 0.0 5.1 5 1 0 5 5 5 3 double strand RNA binding domain from DEAD END PROTEIN 1 LPP20 PF02169.11 KFP04129.1 - 0.029 14.4 0.3 7.7 6.6 0.0 3.4 3 0 0 3 3 3 0 LPP20 lipoprotein Guanylin PF02058.10 KFP04129.1 - 0.37 10.8 2.2 6.9 6.8 0.3 3.0 2 0 0 2 2 2 0 Guanylin precursor Pro-NT_NN PF07421.6 KFP04132.1 - 1.6e-75 252.2 1.0 1.7e-75 252.1 0.7 1.0 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor RA PF00788.18 KFP04133.1 - 1.8e-06 28.3 0.0 8.4e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF3087 PF11286.3 KFP04133.1 - 1.6 7.9 5.0 0.52 9.5 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Phage_Treg PF04761.7 KFP04134.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Homeobox PF00046.24 KFP04135.1 - 5.5e-24 83.5 6.2 1.2e-23 82.4 4.3 1.6 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFP04135.1 - 6.4e-10 38.2 0.6 1.6e-09 36.9 0.4 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFP04135.1 - 0.00036 20.1 0.1 0.00098 18.7 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Staygreen PF12638.2 KFP04135.1 - 0.044 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Staygreen protein IQ PF00612.22 KFP04136.1 - 3.6e-06 26.1 0.1 7e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif NuiA PF07924.6 KFP04136.1 - 0.11 12.3 0.2 1.5 8.7 0.0 2.1 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein LRR_4 PF12799.2 KFP04137.1 - 1.1e-22 79.1 57.5 5.1e-06 25.9 2.2 7.9 4 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP04137.1 - 2.5e-17 62.3 49.6 1.3e-07 31.2 4.3 6.3 2 2 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 KFP04137.1 - 6.9e-05 22.3 51.5 2.1 8.6 0.5 11.0 10 2 2 12 12 12 7 Leucine Rich Repeat IQ PF00612.22 KFP04137.1 - 0.00043 19.6 0.1 0.0011 18.4 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3040 PF11239.3 KFP04137.1 - 0.37 10.8 2.5 1.2 9.2 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) LRR_7 PF13504.1 KFP04137.1 - 1.5 9.3 47.5 1.1 9.6 0.0 11.1 12 0 0 12 12 12 0 Leucine rich repeat SNF PF00209.13 KFP04138.1 - 4.6e-225 748.0 30.3 5.7e-225 747.7 21.0 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Peptidase_M50 PF02163.17 KFP04138.1 - 0.062 12.2 0.0 0.7 8.8 0.0 2.4 1 1 0 1 1 1 0 Peptidase family M50 BNIP3 PF06553.7 KFP04139.1 - 1.1e-17 64.0 0.0 1.4e-17 63.7 0.0 1.3 1 1 0 1 1 1 1 BNIP3 CUE PF02845.11 KFP04140.1 - 1.7e-10 40.1 0.0 3.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain ALIX_LYPXL_bnd PF13949.1 KFP04141.1 - 0.0099 14.8 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF313 PF03754.8 KFP04141.1 - 0.077 12.9 0.3 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF313) 7tm_4 PF13853.1 KFP04142.1 - 5.2e-40 136.5 13.7 5.2e-40 136.5 9.5 2.1 2 0 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP04142.1 - 1.5e-29 102.9 24.4 1.9e-29 102.5 16.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_A14 PF05767.7 KFP04142.1 - 6.8 6.7 8.5 0.13 12.1 0.5 2.1 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 7tm_4 PF13853.1 KFP04143.1 - 5e-40 136.6 13.7 5e-40 136.6 9.5 1.9 3 0 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFP04143.1 - 2.6e-31 108.6 16.2 3.3e-31 108.3 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4013 PF13197.1 KFP04143.1 - 0.53 9.5 7.2 0.052 12.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) 7tm_4 PF13853.1 KFP04144.1 - 2.5e-41 140.8 20.6 2.5e-41 140.8 14.3 2.7 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP04144.1 - 4e-33 114.6 29.3 5.2e-33 114.2 20.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.1 KFP04145.1 - 6.4e-42 142.7 10.8 6.4e-42 142.7 7.5 2.5 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP04145.1 - 1.8e-30 105.9 19.7 2.3e-30 105.5 13.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04145.1 - 0.036 13.2 20.8 0.16 11.1 9.2 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3814 PF12769.2 KFP04145.1 - 0.61 10.2 7.3 0.15 12.2 1.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3814) 7tm_4 PF13853.1 KFP04146.1 - 3.3e-41 140.4 11.3 3.3e-41 140.4 7.9 2.5 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP04146.1 - 9.9e-30 103.5 20.3 1.3e-29 103.1 14.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3814 PF12769.2 KFP04146.1 - 5.1 7.3 9.2 0.15 12.2 1.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3814) 7tm_4 PF13853.1 KFP04147.1 - 6.2e-39 133.0 15.2 6.2e-39 133.0 10.5 2.0 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP04147.1 - 4e-30 104.8 15.4 5.5e-30 104.3 10.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SPRY PF00622.23 KFP04148.1 - 5.2e-17 62.0 0.2 6.7e-17 61.7 0.2 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFP04148.1 - 7.4e-17 60.6 0.0 1.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain GNT-I PF03071.10 KFP04149.1 - 9e-173 574.7 0.0 7.9e-172 571.6 0.0 1.9 1 1 1 2 2 2 1 GNT-I family Glyco_tranf_2_3 PF13641.1 KFP04149.1 - 0.00042 20.1 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 7tm_1 PF00001.16 KFP04150.1 - 3.3e-29 101.8 12.5 3.7e-29 101.6 8.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP04150.1 - 4.9e-06 25.8 6.6 6.7e-06 25.4 4.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.8 KFP04150.1 - 9.4e-05 21.4 0.7 0.00011 21.2 0.5 1.1 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) BCD PF15461.1 KFP04150.1 - 0.00035 20.0 6.4 0.00079 18.9 4.4 1.6 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase DUF2975 PF11188.3 KFP04150.1 - 0.0011 18.6 4.8 0.0015 18.2 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) DUF1201 PF06716.6 KFP04150.1 - 0.0064 16.2 0.5 0.0064 16.2 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1201) Anoctamin PF04547.7 KFP04150.1 - 0.018 13.7 3.1 0.026 13.1 2.2 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel UbiA PF01040.13 KFP04150.1 - 0.025 13.7 5.1 0.031 13.5 3.6 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family PufQ PF05398.6 KFP04150.1 - 2.4 8.2 4.9 1.7 8.7 0.1 2.4 1 1 1 2 2 2 0 PufQ cytochrome subunit zf-LITAF-like PF10601.4 KFP04150.1 - 2.6 7.9 10.1 8.1 6.3 1.4 2.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Epimerase PF01370.16 KFP04151.1 - 3.8e-31 108.3 1.4 1.2e-20 73.9 0.0 3.2 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family UXS1_N PF11803.3 KFP04151.1 - 1.7e-21 75.7 0.1 3.8e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal RmlD_sub_bind PF04321.12 KFP04151.1 - 2.4e-06 26.6 0.0 0.027 13.3 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFP04151.1 - 0.00023 20.2 1.0 0.14 11.0 0.1 3.1 3 1 0 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.14 KFP04151.1 - 0.00029 19.6 0.5 0.0033 16.1 0.1 2.7 2 2 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KFP04151.1 - 0.0021 17.0 0.2 0.47 9.3 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KFP04151.1 - 0.0082 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFP04151.1 - 0.15 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Augurin PF15187.1 KFP04152.1 - 9e-49 164.1 2.7 9.7e-49 163.9 1.9 1.0 1 0 0 1 1 1 1 Oesophageal cancer-related gene 4 SH3_9 PF14604.1 KFP04153.1 - 7.1e-43 143.9 5.5 2.4e-15 55.8 0.1 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 KFP04153.1 - 6.6e-42 140.6 11.8 5.5e-14 51.2 0.1 4.8 6 0 0 6 6 6 3 SH3 domain SH3_2 PF07653.12 KFP04153.1 - 3.7e-30 103.1 7.5 5.6e-10 38.5 0.1 4.3 4 1 1 5 5 5 3 Variant SH3 domain SH2 PF00017.19 KFP04153.1 - 4.8e-22 77.5 0.1 9.7e-22 76.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_3 PF08239.6 KFP04153.1 - 6.5e-11 42.2 9.7 0.0011 19.1 0.2 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain hSH3 PF14603.1 KFP04153.1 - 0.045 13.7 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Helically-extended SH3 domain LIM PF00412.17 KFP04154.1 - 1.6e-46 156.1 71.3 4.4e-13 49.0 5.2 5.1 5 0 0 5 5 5 5 LIM domain Ureidogly_hydro PF04115.7 KFP04154.1 - 0.04 13.2 0.0 0.29 10.4 0.0 2.2 1 1 1 2 2 2 0 Ureidoglycolate hydrolase Ashwin PF15323.1 KFP04155.1 - 5.4e-66 222.6 10.8 6.1e-66 222.5 7.5 1.0 1 0 0 1 1 1 1 Developmental protein Vps39_2 PF10367.4 KFP04156.1 - 3.3e-26 91.5 0.0 8e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KFP04156.1 - 1.2e-25 89.5 7.2 1.7e-25 89.1 1.0 2.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 KFP04156.1 - 2.6e-14 53.3 0.1 7.3e-14 51.8 0.0 1.8 1 1 1 2 2 2 1 CNH domain Clathrin PF00637.15 KFP04156.1 - 1e-13 51.0 16.4 2.2e-08 33.8 4.9 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_2 PF07719.12 KFP04156.1 - 0.35 10.9 4.8 3 7.9 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFP04156.1 - 3.8 7.2 6.4 40 4.0 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.14 KFP04157.1 - 1.2e-33 115.8 0.1 2.1e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Claudin_2 PF13903.1 KFP04159.1 - 1.8e-32 112.3 7.7 2.5e-32 111.9 5.3 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP04159.1 - 0.00017 21.3 9.0 0.071 12.7 3.3 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF2207 PF09972.4 KFP04159.1 - 0.038 12.5 1.4 0.058 11.9 1.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MnhB PF04039.8 KFP04159.1 - 0.1 12.6 11.2 0.67 10.0 2.0 2.2 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF3681 PF12442.3 KFP04159.1 - 0.19 11.9 2.8 0.38 10.9 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) DUF4191 PF13829.1 KFP04159.1 - 3.4 6.7 4.4 5.5 6.0 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) MFS_1 PF07690.11 KFP04160.1 - 3.9e-39 134.3 22.4 4.8e-39 134.0 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP04160.1 - 2.7e-09 36.1 3.1 2.7e-09 36.1 2.2 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Na_H_Exchanger PF00999.16 KFP04161.1 - 2.4e-86 289.6 41.3 2.7e-86 289.4 28.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.16 KFP04162.1 - 2.3e-79 266.6 36.3 2.7e-79 266.4 25.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TIR PF01582.15 KFP04163.1 - 2.8e-32 111.0 0.0 5.5e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFP04163.1 - 8.2e-14 51.4 2.1 0.00037 20.5 0.5 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFP04163.1 - 6.3e-11 41.9 2.1 0.0017 18.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP04163.1 - 2.6e-07 31.0 3.4 0.04 14.4 0.0 4.0 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFP04163.1 - 1.2e-05 25.3 4.5 0.41 10.8 0.0 4.1 3 3 0 3 3 3 2 Immunoglobulin domain TIR_2 PF13676.1 KFP04163.1 - 4e-05 23.7 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 TIR domain C1-set PF07654.10 KFP04163.1 - 0.0012 18.8 0.9 1.3 9.0 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin C1-set domain V-set_CD47 PF08204.6 KFP04163.1 - 0.0072 16.0 1.3 0.04 13.6 0.1 2.6 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain TIR PF01582.15 KFP04164.1 - 3.5e-33 114.0 0.1 6.9e-33 113.0 0.1 1.5 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFP04164.1 - 7.1e-10 38.8 5.9 5.5e-06 26.4 0.2 3.4 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFP04164.1 - 2.1e-07 31.3 7.2 0.0004 20.8 0.3 3.7 3 1 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP04164.1 - 7.6e-05 22.7 3.8 0.057 13.5 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFP04164.1 - 0.00063 19.6 7.5 0.37 10.6 0.7 4.5 3 2 0 3 3 3 2 Immunoglobulin V-set domain I-set PF07679.11 KFP04164.1 - 0.002 17.9 7.6 0.64 9.9 0.1 4.0 5 0 0 5 5 5 2 Immunoglobulin I-set domain TIR_2 PF13676.1 KFP04164.1 - 0.0066 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 TIR domain KSHV_K1 PF11049.3 KFP04164.1 - 0.025 14.5 0.1 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus TIR PF01582.15 KFP04165.1 - 1.7e-31 108.5 1.0 2.8e-31 107.8 0.7 1.4 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFP04165.1 - 1.4e-19 69.9 0.8 7.4e-06 26.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP04165.1 - 2.2e-16 60.1 2.7 0.00023 21.6 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFP04165.1 - 2e-13 50.0 2.5 3.8e-05 23.4 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.20 KFP04165.1 - 1.2e-10 41.3 9.5 0.0002 21.4 0.2 4.4 5 1 0 5 5 5 2 Immunoglobulin domain V-set PF07686.12 KFP04165.1 - 6e-08 32.5 1.8 0.0039 17.0 0.1 4.0 3 2 0 3 3 3 2 Immunoglobulin V-set domain TIR_2 PF13676.1 KFP04165.1 - 0.0017 18.4 0.0 0.0038 17.3 0.0 1.6 1 1 0 1 1 1 1 TIR domain V-set_CD47 PF08204.6 KFP04165.1 - 0.0024 17.6 1.0 0.37 10.5 0.0 3.1 3 0 0 3 3 3 1 CD47 immunoglobulin-like domain BiPBP_C PF06832.7 KFP04165.1 - 0.011 15.6 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family TIR PF01582.15 KFP04166.1 - 1.1e-29 102.6 0.0 1.8e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFP04166.1 - 4.9e-20 71.4 0.5 5.5e-07 29.6 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFP04166.1 - 1.3e-19 69.8 0.2 1.5e-05 24.7 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP04166.1 - 2.9e-09 37.3 5.5 0.00065 20.1 0.3 3.8 3 1 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFP04166.1 - 2.4e-06 27.5 4.5 0.069 13.2 0.1 4.3 4 1 0 4 4 4 3 Immunoglobulin domain V-set PF07686.12 KFP04166.1 - 2.5e-06 27.3 9.7 0.002 18.0 0.4 4.8 2 2 1 3 3 3 2 Immunoglobulin V-set domain Herpes_gE PF02480.11 KFP04166.1 - 0.04 12.2 0.0 0.078 11.2 0.0 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E C2-set_2 PF08205.7 KFP04166.1 - 0.043 13.7 0.0 1.7 8.6 0.0 2.9 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain TIR PF01582.15 KFP04167.1 - 5.9e-37 126.2 0.1 2.7e-36 124.0 0.0 2.1 3 0 0 3 3 3 1 TIR domain Ig_2 PF13895.1 KFP04167.1 - 1e-15 57.6 0.0 1.4e-06 28.2 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 KFP04167.1 - 3.2e-14 52.5 0.0 0.00013 21.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.20 KFP04167.1 - 3.3e-09 36.7 0.0 0.0028 17.7 0.0 3.6 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFP04167.1 - 4.3e-08 33.5 0.1 0.72 10.3 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP04167.1 - 2.1e-05 24.3 1.4 0.059 13.2 0.3 3.7 3 2 0 3 3 3 2 Immunoglobulin V-set domain TIR_2 PF13676.1 KFP04167.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 TIR domain Ig_2 PF13895.1 KFP04168.1 - 3.2e-14 52.8 0.4 0.00012 22.0 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP04168.1 - 5e-11 42.5 5.2 0.012 15.7 0.0 5.2 3 2 0 3 3 3 3 Immunoglobulin domain I-set PF07679.11 KFP04168.1 - 3.2e-10 39.7 0.0 0.0068 16.2 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP04168.1 - 1e-05 25.9 5.5 0.41 11.1 0.4 4.3 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFP04168.1 - 2.1e-05 24.3 2.6 0.15 11.9 0.0 3.9 3 2 0 3 3 3 2 Immunoglobulin V-set domain DUF4516 PF14990.1 KFP04168.1 - 0.0063 16.0 0.2 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) CNH PF00780.17 KFP04169.1 - 1e-59 202.2 0.0 1.5e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFP04169.1 - 2.6e-57 193.9 0.0 5.6e-57 192.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04169.1 - 2e-40 138.4 0.0 3.5e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP04169.1 - 0.00019 20.5 1.0 0.00059 18.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Borrelia_P83 PF05262.6 KFP04169.1 - 0.14 10.4 25.0 0.23 9.6 17.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pyrid_oxidase_2 PF13883.1 KFP04170.1 - 1.8e-46 157.9 0.0 2e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 KFP04170.1 - 9.6e-05 22.3 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-RING_2 PF13639.1 KFP04171.1 - 2.1e-14 53.0 7.2 3.3e-14 52.4 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFP04171.1 - 5.7e-10 38.7 0.1 1.2e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFP04171.1 - 8.1e-10 38.6 3.3 1.7e-09 37.6 2.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP04171.1 - 1.3e-07 31.1 7.3 2.2e-07 30.4 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP04171.1 - 2.8e-07 30.1 5.1 4.4e-07 29.5 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP04171.1 - 1.2e-06 28.0 4.3 1.9e-06 27.4 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP04171.1 - 1.4e-06 28.2 8.1 2.4e-06 27.4 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UPF0233 PF06781.7 KFP04171.1 - 0.0031 17.1 2.1 0.0053 16.3 0.6 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0233) zf-Apc11 PF12861.2 KFP04171.1 - 0.024 14.4 4.4 0.049 13.4 3.1 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PspB PF06667.7 KFP04171.1 - 0.076 12.9 1.0 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Phage shock protein B zf-RING_UBOX PF13445.1 KFP04171.1 - 0.091 12.4 3.7 0.2 11.4 2.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 KFP04171.1 - 0.18 11.5 5.2 0.1 12.3 1.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 KFP04171.1 - 0.84 9.2 4.8 0.79 9.3 2.3 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.24 KFP04171.1 - 1.6 8.4 4.6 3.5 7.3 3.2 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 KFP04171.1 - 2.4 8.1 5.2 13 5.8 3.8 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KFP04171.1 - 3.8 7.6 6.2 7.7 6.6 4.3 1.5 1 0 0 1 1 1 0 RING-variant domain DUF2363 PF10155.4 KFP04172.1 - 4.5e-54 181.7 6.6 6.2e-54 181.2 4.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) Ribosomal_L31e PF01198.14 KFP04173.1 - 2.1e-40 136.2 2.8 2.9e-40 135.8 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.10 KFP04173.1 - 0.051 13.1 0.1 0.098 12.2 0.0 1.5 1 1 0 1 1 1 0 DNA mismatch endonuclease Vsr PAS_11 PF14598.1 KFP04174.1 - 5e-23 81.1 5.2 3.6e-22 78.3 0.0 3.7 5 0 0 5 5 5 1 PAS domain PAS_3 PF08447.6 KFP04174.1 - 9.8e-15 54.4 0.1 1.4e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KFP04174.1 - 2.3e-11 43.4 0.0 5.3e-08 32.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFP04174.1 - 6.6e-08 32.1 0.2 2.2e-07 30.4 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 KFP04174.1 - 0.042 14.2 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 PAS domain RNA_pol_Rpb4 PF03874.11 KFP04174.1 - 0.14 12.1 5.2 5.5 7.0 0.3 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb4 Phosducin PF02114.11 KFP04175.1 - 8.6e-17 60.7 0.9 1.1e-16 60.4 0.4 1.3 1 1 0 1 1 1 1 Phosducin OmpH PF03938.9 KFP04175.1 - 0.052 13.4 2.9 0.087 12.7 2.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Histone PF00125.19 KFP04176.1 - 1.2e-21 76.6 0.0 1.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFP04176.1 - 0.00013 21.9 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sulfotransfer_2 PF03567.9 KFP04177.1 - 8.8e-52 176.2 0.1 1.1e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family LON PF02190.11 KFP04178.1 - 1e-25 90.6 0.0 2.1e-25 89.6 0.0 1.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KFP04178.1 - 1.9e-09 37.3 15.2 4.5e-09 36.1 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP04178.1 - 3.4e-09 36.2 9.8 6.5e-09 35.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP04178.1 - 3e-08 33.3 15.4 3e-08 33.3 10.7 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFP04178.1 - 2.5e-07 30.2 14.7 6.2e-07 28.9 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP04178.1 - 1.3e-06 28.2 11.6 3.7e-06 26.7 8.1 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFP04178.1 - 1.9e-06 27.5 13.7 3.8e-06 26.5 9.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.10 KFP04178.1 - 0.00061 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 KFP04178.1 - 0.0016 18.1 6.2 0.0016 18.1 4.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFP04178.1 - 0.0077 15.7 9.8 0.018 14.5 6.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KFP04178.1 - 0.014 15.2 6.1 0.032 14.0 4.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KFP04178.1 - 0.018 15.1 7.9 0.046 13.8 5.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger DUF35_N PF12172.3 KFP04178.1 - 0.086 12.7 0.0 0.086 12.7 0.0 2.1 2 0 0 2 2 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Prok-RING_4 PF14447.1 KFP04178.1 - 1.1 8.8 9.1 3 7.4 6.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AF-4 PF05110.8 KFP04179.1 - 1.9e-87 294.3 20.3 1.1e-55 189.1 4.0 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein AF-4 PF05110.8 KFP04180.1 - 1.4e-107 361.1 53.0 9.2e-59 199.4 23.1 2.0 1 1 1 2 2 2 2 AF-4 proto-oncoprotein MACPF PF01823.14 KFP04180.1 - 3.6 7.2 11.3 0.046 13.4 2.4 1.7 2 0 0 2 2 2 0 MAC/Perforin domain IMS PF00817.15 KFP04181.1 - 1.4e-42 144.9 0.0 2.7e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KFP04181.1 - 1.8e-19 69.9 0.5 5.1e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KFP04181.1 - 8.3e-08 32.1 1.7 0.0024 17.7 0.2 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 KFP04181.1 - 1.4e-07 31.5 0.0 3.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 KFP04181.1 - 3.3e-05 23.6 0.0 0.0026 17.7 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 KFP04181.1 - 0.00016 21.4 0.0 0.0004 20.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 KFP04181.1 - 0.0029 17.7 0.0 0.0089 16.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.3 KFP04181.1 - 0.016 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.6 KFP04181.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Thioredoxin PF00085.15 KFP04182.1 - 1.3e-10 40.8 0.1 2.9e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KFP04182.1 - 5.1e-09 35.2 0.6 6.7e-09 34.8 0.4 1.1 1 0 0 1 1 1 1 Phosducin CRF PF00473.12 KFP04182.1 - 0.1 12.6 0.6 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Corticotropin-releasing factor family BAG PF02179.11 KFP04182.1 - 0.97 9.5 9.7 0.47 10.5 4.7 2.0 2 0 0 2 2 2 0 BAG domain DUF342 PF03961.8 KFP04182.1 - 1.6 7.0 5.6 1.8 6.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SLT PF01464.15 KFP04183.1 - 2.5e-07 30.2 0.0 4.2e-07 29.4 0.0 1.4 2 0 0 2 2 2 1 Transglycosylase SLT domain SLT PF01464.15 KFP04184.1 - 9.8e-15 54.1 0.0 1.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Pex19 PF04614.7 KFP04184.1 - 0.086 12.4 0.0 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 Pex19 protein family Ribosomal_L30 PF00327.15 KFP04185.1 - 5.8e-11 41.8 1.0 8.7e-11 41.2 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e BPL_LplA_LipB PF03099.14 KFP04186.1 - 6.3e-18 64.9 0.1 2.4e-17 63.1 0.0 1.8 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family DUF4592 PF15262.1 KFP04187.1 - 1.6e-30 106.2 4.6 1.6e-30 106.2 3.2 3.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4592) Glyco_transf_54 PF04666.8 KFP04189.1 - 2.7e-133 443.3 0.8 3.6e-133 442.9 0.6 1.1 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF3989 PF13150.1 KFP04189.1 - 0.022 14.2 0.2 0.51 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) GAS PF13851.1 KFP04189.1 - 0.042 13.0 1.4 0.076 12.1 1.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UNC-50 PF05216.8 KFP04190.1 - 2e-90 302.0 21.5 2.3e-90 301.8 14.9 1.0 1 0 0 1 1 1 1 UNC-50 family C2 PF00168.25 KFP04191.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain NHR2 PF08788.6 KFP04191.1 - 0.0058 16.0 0.7 0.18 11.3 0.1 2.7 2 0 0 2 2 2 1 NHR2 domain like DUF3651 PF12371.3 KFP04192.1 - 3.3e-46 155.1 14.0 2.6e-24 85.0 0.8 5.2 5 0 0 5 5 5 3 Protein of unknown function (DUF3651) VWA_3 PF13768.1 KFP04193.1 - 0.021 14.5 0.4 0.032 13.9 0.3 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Ion_trans PF00520.26 KFP04194.1 - 1.3e-18 67.0 4.7 2e-18 66.4 3.2 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 KFP04194.1 - 6.1e-17 61.2 0.0 1.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ycf1 PF05758.7 KFP04194.1 - 3.3e-05 21.8 1.2 6.5e-05 20.8 0.8 1.6 1 0 0 1 1 1 1 Ycf1 CDC45 PF02724.9 KFP04194.1 - 0.00018 19.7 1.5 0.00018 19.7 1.0 2.0 2 0 0 2 2 2 1 CDC45-like protein RR_TM4-6 PF06459.7 KFP04194.1 - 0.0012 18.7 10.4 0.0012 18.7 7.2 1.8 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 Zip PF02535.17 KFP04194.1 - 0.12 11.3 2.3 0.19 10.7 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ion_trans_2 PF07885.11 KFP04194.1 - 0.16 11.7 5.6 0.54 10.0 3.9 2.0 1 1 0 1 1 1 0 Ion channel Baculo_PEP_C PF04513.7 KFP04194.1 - 0.2 11.4 0.1 0.68 9.7 0.0 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 KFP04194.1 - 0.22 11.4 1.3 4.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DHHW PF14286.1 KFP04194.1 - 0.23 10.7 6.9 0.45 9.7 4.8 1.4 1 0 0 1 1 1 0 DHHW protein GAGA_bind PF06217.7 KFP04194.1 - 0.66 9.8 13.9 0.051 13.5 6.2 1.6 2 0 0 2 2 2 0 GAGA binding protein-like family DDHD PF02862.12 KFP04194.1 - 0.8 9.4 10.4 1.7 8.3 7.2 1.5 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.3 KFP04194.1 - 1.4 7.3 14.7 2.5 6.5 10.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.8 KFP04194.1 - 1.5 7.2 10.7 2.5 6.5 7.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.11 KFP04194.1 - 1.7 8.4 3.6 1.1 9.0 0.6 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.1 KFP04194.1 - 2.4 8.4 24.2 1.1 9.5 7.7 2.5 2 1 0 2 2 2 0 AAA domain HECT PF00632.20 KFP04195.1 - 7.5e-95 317.7 0.6 1.4e-94 316.7 0.1 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AhpC-TSA_2 PF13911.1 KFP04195.1 - 0.085 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Hydrolase PF00702.21 KFP04197.1 - 6.3e-14 52.9 0.1 2.3e-09 38.0 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFP04197.1 - 1.8e-13 51.1 0.3 1.3e-12 48.3 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP04197.1 - 8.7e-09 35.2 0.0 4.6e-08 32.9 0.0 2.3 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KFP04197.1 - 8.3e-06 24.9 0.0 2.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 KFP04197.1 - 0.00054 19.6 0.8 0.002 17.7 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Yae1_N PF09811.4 KFP04198.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Neur_chan_memb PF02932.11 KFP04199.1 - 4.9e-55 187.0 1.6 3e-54 184.4 1.1 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP04199.1 - 1.1e-40 139.1 0.0 1.7e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain OAD_gamma PF04277.8 KFP04199.1 - 0.017 15.4 0.1 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Neur_chan_LBD PF02931.18 KFP04200.1 - 4.3e-51 173.1 0.0 6e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP04200.1 - 5.1e-47 160.7 5.1 6.9e-39 134.1 2.1 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP04201.1 - 1.9e-45 154.6 2.6 2.6e-45 154.2 1.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP04201.1 - 7.8e-45 153.6 10.8 2.7e-40 138.7 4.8 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RDD PF06271.7 KFP04201.1 - 0.034 14.0 3.1 0.092 12.6 2.1 1.7 1 0 0 1 1 1 0 RDD family CitMHS PF03600.11 KFP04202.1 - 1.5e-77 260.5 20.7 7.1e-72 241.8 5.5 2.3 2 1 1 3 3 3 2 Citrate transporter Na_sulph_symp PF00939.14 KFP04202.1 - 4.7e-16 58.7 34.7 2.6e-11 43.0 10.3 2.7 2 2 0 2 2 2 2 Sodium:sulfate symporter transmembrane region ArsB PF02040.10 KFP04202.1 - 4e-12 45.8 26.4 1.5e-07 30.7 7.2 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein MatC_N PF07158.6 KFP04202.1 - 0.0084 15.9 12.2 0.0084 15.9 8.5 3.0 3 0 0 3 3 3 1 Dicarboxylate carrier protein MatC N-terminus RCC1 PF00415.13 KFP04203.1 - 2.9e-241 779.8 89.7 8.7e-16 57.8 0.1 21.8 21 0 0 21 21 21 19 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFP04203.1 - 1.2e-94 308.3 126.9 4.1e-08 32.6 0.1 22.2 23 0 0 23 23 22 17 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 KFP04203.1 - 9.1e-64 215.5 0.0 1.5e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cul7 PF11515.3 KFP04203.1 - 1.7e-39 133.5 0.7 1.7e-39 133.5 0.5 1.9 2 0 0 2 2 2 1 Mouse development and cellular proliferation protein Cullin-7 MIB_HERC2 PF06701.8 KFP04203.1 - 2e-26 91.7 3.0 2e-26 91.7 2.1 5.4 7 0 0 7 7 5 1 Mib_herc2 Cyt-b5 PF00173.23 KFP04203.1 - 4.2e-12 45.6 0.0 9e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ZZ PF00569.12 KFP04203.1 - 3e-09 36.2 7.0 7.1e-09 35.0 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type APC10 PF03256.11 KFP04203.1 - 1.9e-05 24.3 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) SUKH-3 PF14433.1 KFP04203.1 - 0.0017 18.1 12.7 6.4 6.5 0.0 7.3 9 0 0 9 9 9 2 SUKH-3 immunity protein Ubie_methyltran PF01209.13 KFP04203.1 - 0.09 11.8 0.7 17 4.4 0.0 3.7 4 0 0 4 4 4 0 ubiE/COQ5 methyltransferase family CBM_X PF06204.6 KFP04203.1 - 0.82 9.1 16.1 30 4.1 0.1 8.2 10 0 0 10 10 10 0 Putative carbohydrate binding domain Mg_trans_NIPA PF05653.9 KFP04204.1 - 6.7e-70 235.4 14.9 7.5e-70 235.2 10.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KFP04204.1 - 0.0081 16.1 4.8 0.0081 16.1 3.3 3.2 2 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFP04204.1 - 0.027 14.6 0.6 0.027 14.6 0.4 3.6 2 1 1 3 3 3 0 Multidrug resistance efflux transporter MgtE PF01769.11 KFP04204.1 - 0.29 11.3 9.4 0.15 12.3 0.3 2.5 1 1 1 2 2 2 0 Divalent cation transporter TPT PF03151.11 KFP04204.1 - 0.31 10.6 17.2 1 8.9 6.5 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF2678 PF10856.3 KFP04204.1 - 0.38 10.5 16.2 1.3 8.7 1.7 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF2678) Cortexin PF11057.3 KFP04204.1 - 0.42 10.2 3.0 0.32 10.6 0.2 2.1 2 0 0 2 2 2 0 Cortexin of kidney Mg_trans_NIPA PF05653.9 KFP04205.1 - 7.3e-148 491.3 15.2 8.5e-148 491.1 10.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFP04205.1 - 3.9e-09 36.7 1.8 3.9e-09 36.7 1.2 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFP04205.1 - 4.7e-08 33.1 5.7 4.7e-08 33.1 3.9 3.8 3 1 1 4 4 4 1 EamA-like transporter family FragX_IP PF05994.6 KFP04206.1 - 0 1139.7 13.6 0 1139.4 2.9 2.1 2 0 0 2 2 2 2 Cytoplasmic Fragile-X interacting family fn3 PF00041.16 KFP04207.1 - 1.5e-05 24.9 0.2 2.5e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Fibronectin type III domain FAM163 PF15069.1 KFP04207.1 - 0.005 17.4 0.5 0.026 15.0 0.0 2.1 2 0 0 2 2 2 1 FAM163 family Interfer-bind PF09294.5 KFP04207.1 - 0.027 14.4 0.4 0.047 13.7 0.3 1.4 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Viral_Beta_CD PF04530.7 KFP04207.1 - 0.032 14.4 0.9 0.051 13.7 0.1 1.7 2 0 0 2 2 2 0 Viral Beta C/D like family TMEM154 PF15102.1 KFP04207.1 - 0.05 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family MLANA PF14991.1 KFP04207.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A DUF347 PF03988.7 KFP04207.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Afaf PF15339.1 KFP04207.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Acrosome formation-associated factor Tmemb_40 PF10160.4 KFP04207.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein Spc97_Spc98 PF04130.8 KFP04208.1 - 7.6e-113 377.6 14.1 9.1e-113 377.4 9.8 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KFP04208.1 - 4.8e-05 21.6 1.4 0.0002 19.6 0.1 2.3 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 GD_AH_C PF04295.8 KFP04208.1 - 0.23 10.0 0.0 0.41 9.2 0.0 1.3 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus TBCC PF07986.7 KFP04209.1 - 3.2e-45 152.3 5.5 5.4e-45 151.6 3.8 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C NDK PF00334.14 KFP04209.1 - 0.00019 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CAP_C PF08603.6 KFP04209.1 - 0.0011 18.3 1.4 0.0021 17.4 1.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal SGL PF08450.7 KFP04210.1 - 3.9e-76 255.6 0.1 4.5e-76 255.4 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 KFP04210.1 - 0.033 14.1 0.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 0 Two component regulator propeller NHL PF01436.16 KFP04210.1 - 0.048 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 NHL repeat SGL PF08450.7 KFP04211.1 - 3.7e-82 275.4 0.0 4.2e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 KFP04211.1 - 0.045 13.7 0.0 1 9.6 0.0 3.0 2 1 0 2 2 2 0 Two component regulator propeller Ldh_2 PF02615.9 KFP04211.1 - 0.099 11.3 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase TEX13 PF15186.1 KFP04211.1 - 0.13 11.8 0.1 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Kelch_6 PF13964.1 KFP04211.1 - 0.35 11.1 3.1 18 5.6 0.0 3.4 4 1 1 5 5 5 0 Kelch motif PI-PLC-X PF00388.14 KFP04212.1 - 8e-06 25.3 0.4 3e-05 23.4 0.3 1.9 1 1 1 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain MMR_HSR1 PF01926.18 KFP04213.1 - 2e-14 53.5 0.1 8.4e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 KFP04213.1 - 2.3e-05 24.4 0.1 7.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal PduV-EutP PF10662.4 KFP04213.1 - 0.0021 17.5 0.2 0.06 12.8 0.0 2.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KFP04213.1 - 0.0023 17.4 0.2 0.49 9.7 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFP04213.1 - 0.0046 16.2 1.3 0.034 13.4 0.9 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 KFP04213.1 - 0.015 14.9 0.1 0.041 13.5 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KFP04213.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KFP04213.1 - 0.029 14.6 0.4 0.12 12.7 0.1 2.0 2 1 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 KFP04213.1 - 0.034 13.8 0.3 0.12 12.0 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 KFP04213.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KFP04213.1 - 0.072 12.2 0.0 5.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFP04213.1 - 0.072 12.9 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain STAG PF08514.6 KFP04214.1 - 1.1e-39 134.8 3.4 6.5e-39 132.2 0.2 2.7 2 0 0 2 2 2 2 STAG domain EF-hand_7 PF13499.1 KFP04215.1 - 1.8e-24 85.6 7.0 1.1e-14 54.2 1.4 3.7 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP04215.1 - 8e-12 43.9 0.0 0.00044 19.4 0.0 4.1 5 0 0 5 5 5 2 EF hand EF-hand_1 PF00036.27 KFP04215.1 - 3.9e-11 41.3 1.3 0.03 13.6 0.1 5.5 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KFP04215.1 - 1.9e-10 39.7 2.6 0.12 12.2 0.0 5.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 KFP04215.1 - 3.8e-08 32.8 0.7 0.6 9.7 0.1 5.6 5 0 0 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP04215.1 - 0.0033 17.4 9.3 0.032 14.2 0.2 3.5 1 1 3 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region DUF4187 PF13821.1 KFP04215.1 - 0.036 13.6 1.8 0.084 12.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Glyco_hydro_108 PF05838.7 KFP04215.1 - 0.039 14.0 0.1 8.8 6.5 0.0 3.3 3 1 1 4 4 4 0 Glycosyl hydrolase 108 Yae1_N PF09811.4 KFP04216.1 - 2.5e-20 71.7 64.3 1.5e+04 -25.0 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Homeobox PF00046.24 KFP04217.1 - 4.8e-25 86.9 2.7 8.9e-25 86.0 1.8 1.5 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFP04217.1 - 1.3e-07 30.8 3.3 3.8e-07 29.3 2.3 1.9 1 0 0 1 1 1 1 OAR domain MRP-L20 PF12824.2 KFP04217.1 - 0.0057 16.6 0.5 0.014 15.3 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.6 KFP04217.1 - 0.0094 15.6 0.1 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain IL6Ra-bind PF09240.5 KFP04218.1 - 3.2e-22 78.5 1.6 3.2e-22 78.5 1.1 1.6 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFP04218.1 - 0.78 9.7 7.7 0.12 12.3 2.1 1.9 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding Mito_carr PF00153.22 KFP04219.1 - 3e-57 190.3 1.5 1.5e-22 79.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Methyltransf_2 PF00891.13 KFP04220.1 - 3.1e-53 180.4 0.0 5.2e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Maf PF02545.9 KFP04220.1 - 6.2e-45 152.7 0.0 1.2e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Maf-like protein Methyltransf_18 PF12847.2 KFP04220.1 - 4.5e-07 30.4 0.0 3.6e-06 27.5 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP04220.1 - 1.4e-06 28.1 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP04220.1 - 1.5e-05 25.3 0.0 0.00018 21.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP04220.1 - 2.8e-05 24.5 0.0 9.1e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain 7tm_1 PF00001.16 KFP04221.1 - 1e-44 152.6 27.3 1.3e-44 152.2 18.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP04221.1 - 0.011 14.8 25.5 0.015 14.4 17.7 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv VHS PF00790.14 KFP04221.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain Peptidase_M50 PF02163.17 KFP04221.1 - 1.2 8.0 3.4 1.6 7.6 2.1 1.5 1 1 0 1 1 1 0 Peptidase family M50 ANF_receptor PF01094.23 KFP04222.1 - 1.1e-31 109.8 0.2 1.4e-31 109.5 0.2 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region DUF2555 PF10742.4 KFP04222.1 - 0.062 12.9 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) PC4 PF02229.11 KFP04223.1 - 1.2e-23 82.0 0.3 2.3e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) QLQ PF08880.6 KFP04223.1 - 0.016 14.5 0.2 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 QLQ RNA_pol_Rpc4 PF05132.9 KFP04223.1 - 0.28 11.1 3.1 0.31 11.0 2.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.7 KFP04223.1 - 0.44 10.3 4.6 0.54 10.0 3.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4557 PF15101.1 KFP04223.1 - 1 9.1 5.6 4.2 7.1 4.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) Dsh_C PF12316.3 KFP04223.1 - 1.8 8.5 7.0 2.4 8.2 4.9 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DZF PF07528.9 KFP04224.1 - 2e-65 220.6 0.0 3.1e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 DZF domain zf-met PF12874.2 KFP04224.1 - 1.9e-21 75.4 15.6 1.7e-06 28.0 1.5 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP04224.1 - 1.8e-13 50.2 20.4 7.6e-05 22.7 1.6 4.0 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP04224.1 - 0.0058 16.7 17.1 1.1 9.3 0.3 4.1 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFP04224.1 - 0.1 12.2 18.3 0.32 10.6 1.8 3.6 3 0 0 3 3 3 0 U1 zinc finger GPP34 PF05719.6 KFP04225.1 - 1.1e-52 179.0 0.5 1.3e-52 178.8 0.4 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.8 KFP04225.1 - 0.14 11.6 0.1 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) PDZ PF00595.19 KFP04227.1 - 1.1e-51 172.8 6.3 6.1e-20 71.1 0.3 4.6 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP04227.1 - 3.7e-16 58.7 0.1 0.0007 19.4 0.0 5.4 5 1 0 5 5 5 4 PDZ domain Collagen PF01391.13 KFP04228.1 - 1.4e-14 53.3 48.4 6.2e-08 32.0 18.2 2.4 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) EGF_CA PF07645.10 KFP04228.1 - 1.5e-09 37.6 8.8 1.5e-09 37.6 6.1 3.0 3 1 0 3 3 3 1 Calcium-binding EGF domain FXa_inhibition PF14670.1 KFP04228.1 - 2.2e-09 37.2 29.2 2.2e-09 37.2 6.0 2.8 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP04228.1 - 7.3e-08 31.9 11.8 4.8e-06 26.0 1.5 3.3 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.22 KFP04228.1 - 4.7e-05 23.2 21.9 0.0001 22.1 2.7 3.1 3 1 0 3 3 3 2 EGF-like domain EGF_3 PF12947.2 KFP04228.1 - 0.00074 19.4 19.0 0.032 14.1 1.4 2.8 2 0 0 2 2 2 2 EGF domain Tme5_EGF_like PF09064.5 KFP04228.1 - 0.0079 15.7 16.5 0.019 14.5 2.3 2.7 2 0 0 2 2 2 2 Thrombomodulin like fifth domain, EGF-like RhoGEF PF00621.15 KFP04229.1 - 4.5e-30 104.8 1.8 6.4e-30 104.3 1.2 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFP04229.1 - 4.3e-06 26.8 0.0 1.2e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 PH domain Myosin_head PF00063.16 KFP04230.1 - 8.6e-149 496.7 0.0 6.9e-148 493.7 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) ER-remodelling PF14755.1 KFP04231.1 - 1.9e-05 24.7 6.2 2.1e-05 24.6 4.3 1.1 1 0 0 1 1 1 1 Intracellular membrane remodeller Ribosomal_L37 PF08561.5 KFP04231.1 - 0.024 14.2 0.1 0.06 12.9 0.1 1.7 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L37 SH2 PF00017.19 KFP04232.1 - 0.0025 17.5 0.0 0.0028 17.4 0.0 1.1 1 0 0 1 1 1 1 SH2 domain Trm56 PF01994.11 KFP04232.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Auxin_inducible PF02519.9 KFP04232.1 - 0.14 12.2 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 Auxin responsive protein Carb_anhydrase PF00194.16 KFP04233.1 - 3.6e-51 173.6 0.0 2.8e-29 101.8 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Aph-1 PF06105.7 KFP04234.1 - 1.8e-81 272.9 10.4 2e-81 272.7 7.2 1.0 1 0 0 1 1 1 1 Aph-1 protein YqfD PF06898.6 KFP04234.1 - 0.073 11.7 0.4 0.099 11.3 0.3 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD DUF3139 PF11337.3 KFP04234.1 - 0.69 10.2 0.1 0.69 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Tropomyosin PF00261.15 KFP04235.1 - 1.5e-90 302.4 75.5 3.1e-83 278.5 32.5 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFP04235.1 - 1.1e-34 119.3 74.0 6.1e-30 103.9 30.2 3.3 1 1 2 3 3 3 3 Tropomyosin like Laminin_II PF06009.7 KFP04235.1 - 0.00017 21.3 33.0 0.00021 21.0 3.2 3.7 1 1 3 4 4 4 3 Laminin Domain II TMF_DNA_bd PF12329.3 KFP04235.1 - 0.0071 16.1 10.1 0.0071 16.1 7.0 5.8 2 2 3 6 6 6 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 KFP04235.1 - 0.008 16.0 27.6 0.008 16.0 19.1 2.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 KFP04235.1 - 0.011 15.8 10.9 0.011 15.8 7.6 4.6 2 1 3 5 5 5 0 Domain of unknown function (DUF4164) Reo_sigmaC PF04582.7 KFP04235.1 - 0.038 13.1 7.6 0.13 11.4 0.4 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KFP04235.1 - 0.085 12.4 57.1 0.12 11.9 8.9 3.4 1 1 2 3 3 3 0 IncA protein SlyX PF04102.7 KFP04235.1 - 0.13 12.6 0.3 0.13 12.6 0.2 6.2 2 2 4 6 6 6 0 SlyX gpW PF02831.10 KFP04235.1 - 0.25 10.8 1.8 5.4 6.6 0.0 2.7 2 0 0 2 2 2 0 gpW AAA_13 PF13166.1 KFP04235.1 - 0.28 9.5 48.9 0.25 9.7 17.7 2.0 1 1 1 2 2 2 0 AAA domain Laminin_I PF06008.9 KFP04235.1 - 0.3 10.3 48.2 0.085 12.1 5.9 3.2 1 1 2 3 3 3 0 Laminin Domain I MAD PF05557.8 KFP04235.1 - 2.1 6.3 55.0 3.6e+02 -1.1 38.1 2.3 1 1 0 1 1 1 0 Mitotic checkpoint protein Baculo_PEP_C PF04513.7 KFP04235.1 - 2.3 8.0 11.2 4.2 7.1 0.6 3.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KFP04235.1 - 3 7.9 32.2 1.2 9.2 3.4 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 KFP04235.1 - 3.2 6.6 60.6 0.92 8.4 14.2 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 GTPase_Cys_C PF12631.2 KFP04235.1 - 5 7.6 18.1 0.97 9.8 1.8 4.4 2 2 3 5 5 5 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Spectrin PF00435.16 KFP04235.1 - 5.4 7.3 43.6 0.19 12.0 2.8 4.5 1 1 3 4 4 4 0 Spectrin repeat Suppressor_APC PF11414.3 KFP04235.1 - 6.4 6.6 21.2 0.83 9.4 4.0 3.6 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein ATG16 PF08614.6 KFP04235.1 - 7.2 6.3 51.3 0.19 11.5 4.5 3.4 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Avidin PF01382.12 KFP04236.1 - 5.4e-26 91.1 1.4 6.2e-26 90.9 1.0 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.12 KFP04237.1 - 1.9e-32 111.9 2.2 2.1e-32 111.7 1.6 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.12 KFP04238.1 - 4e-34 117.3 3.3 4.5e-34 117.1 2.3 1.0 1 0 0 1 1 1 1 Avidin family Flocculin PF00624.13 KFP04238.1 - 0.65 9.8 2.9 0.34 10.7 0.2 1.8 2 0 0 2 2 2 0 Flocculin repeat DUF608 PF04685.8 KFP04239.1 - 4.9e-151 502.5 6.7 4.9e-151 502.5 4.7 1.8 3 0 0 3 3 3 1 Protein of unknown function, DUF608 GBA2_N PF12215.3 KFP04239.1 - 1.8e-80 270.3 0.0 2.5e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal Bac_rhamnosid PF05592.6 KFP04239.1 - 0.0024 16.1 1.0 0.0037 15.5 0.7 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase GDE_C PF06202.9 KFP04239.1 - 0.0078 14.9 0.2 0.013 14.2 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Rgp1 PF08737.5 KFP04240.1 - 2.1e-59 201.7 2.5 3.2e-40 138.4 0.4 3.1 2 1 1 3 3 3 3 Rgp1 PSP94 PF05825.6 KFP04241.1 - 2.2e-09 37.4 5.5 2.8e-09 37.1 3.8 1.1 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.13 KFP04241.1 - 0.041 13.9 3.5 0.086 12.9 2.4 1.7 1 1 0 1 1 1 0 von Willebrand factor type C domain TILa PF12714.2 KFP04241.1 - 0.71 9.6 7.3 2 8.2 5.1 1.9 1 1 0 1 1 1 0 TILa domain ANF_receptor PF01094.23 KFP04242.1 - 3.2e-21 75.5 0.1 3.6e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 KFP04242.1 - 0.018 14.4 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Peripla_BP_5 PF13433.1 KFP04242.1 - 0.085 11.5 0.0 0.092 11.4 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Guanylate_cyc PF00211.15 KFP04243.1 - 5.2e-39 133.5 0.1 4.1e-37 127.3 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFP04243.1 - 1.1e-05 24.7 0.5 1.6e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.12 KFP04243.1 - 0.00031 19.9 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase dsDNA_bind PF01984.15 KFP04243.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Fe_bilin_red PF05996.7 KFP04243.1 - 0.012 15.0 0.4 3.2 7.1 0.2 2.1 1 1 1 2 2 2 0 Ferredoxin-dependent bilin reductase Pkinase PF00069.20 KFP04243.1 - 0.045 12.8 0.2 0.7 8.9 0.0 2.5 3 0 0 3 3 3 0 Protein kinase domain HIT PF01230.18 KFP04244.1 - 1.7e-21 76.5 0.1 1.9e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFP04244.1 - 6.6e-18 65.0 0.0 7.5e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3522 PF12036.3 KFP04246.1 - 6e-12 45.7 2.8 8.9e-12 45.1 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Lectin_C PF00059.16 KFP04248.1 - 2.7e-07 31.1 5.6 1.6e-06 28.6 3.9 2.2 1 1 0 1 1 1 1 Lectin C-type domain CENP-F_leu_zip PF10473.4 KFP04248.1 - 0.00024 20.9 1.4 0.00037 20.3 1.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.4 KFP04248.1 - 0.0011 17.1 3.5 0.0014 16.7 2.4 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone MscS_porin PF12795.2 KFP04248.1 - 0.002 17.4 8.5 0.0028 17.0 5.9 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain ATG16 PF08614.6 KFP04248.1 - 0.0037 17.1 0.5 0.0055 16.5 0.3 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 KFP04248.1 - 0.01 15.4 1.4 0.014 14.9 0.9 1.3 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 KFP04248.1 - 0.044 12.4 0.3 0.067 11.8 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 KFP04248.1 - 0.078 12.7 4.6 0.86 9.3 0.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 KFP04248.1 - 0.4 10.5 2.2 17 5.3 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.3 KFP04248.1 - 1.5 8.1 5.6 2.2 7.6 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) FliJ PF02050.11 KFP04248.1 - 2.2 8.3 7.0 13 5.9 1.2 2.2 1 1 0 2 2 2 0 Flagellar FliJ protein Pkinase_Tyr PF07714.12 KFP04249.1 - 5.9e-46 156.6 0.0 7.2e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP04249.1 - 8.4e-42 143.1 0.0 1.2e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KFP04249.1 - 0.00084 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP04249.1 - 0.066 12.9 0.0 2.7 7.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Y_phosphatase PF00102.22 KFP04250.1 - 2.6e-16 59.7 0.1 2.7e-16 59.6 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP04250.1 - 3.8e-06 26.5 0.1 4.9e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFP04251.1 - 7.7e-104 346.1 0.0 5.2e-85 284.5 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFP04251.1 - 5e-06 26.1 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP04251.1 - 0.0018 18.5 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Gly_kinase PF02595.10 KFP04251.1 - 0.0041 15.8 0.0 0.062 11.9 0.0 2.0 2 0 0 2 2 2 1 Glycerate kinase family PTPlike_phytase PF14566.1 KFP04251.1 - 0.036 14.1 0.3 0.094 12.7 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate HAD PF12710.2 KFP04252.1 - 1.2e-15 58.2 0.7 3.7e-15 56.5 0.5 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFP04252.1 - 4.7e-15 55.2 0.0 1e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFP04252.1 - 2.5e-12 47.6 0.1 8.6e-05 23.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP04252.1 - 3e-10 39.9 0.0 1.3e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFP04252.1 - 0.00029 20.4 0.0 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFP04252.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase C2 PF00168.25 KFP04253.1 - 2.6e-06 27.1 0.2 3.7e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 C2 domain nlz1 PF12402.3 KFP04254.1 - 0.022 15.0 0.5 0.058 13.7 0.3 1.7 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 DUF4210 PF13915.1 KFP04255.1 - 1.8e-22 79.4 0.0 3.8e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KFP04255.1 - 2.7e-16 59.1 0.2 9.1e-16 57.4 0.1 1.9 2 0 0 2 2 2 1 Chromosome segregation during meiosis Band_7 PF01145.20 KFP04256.1 - 1.1e-31 110.0 6.1 1.4e-31 109.7 2.3 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFP04256.1 - 0.038 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Blt1 PF12754.2 KFP04256.1 - 0.056 13.0 2.6 0.082 12.4 1.8 1.2 1 0 0 1 1 1 0 Cell-cycle control medial ring component Phosphodiest PF01663.17 KFP04257.1 - 2.6e-13 50.0 0.0 4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFP04257.1 - 0.00015 21.2 2.0 0.00038 19.9 1.4 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily TPR_11 PF13414.1 KFP04258.1 - 5.5e-21 73.9 5.0 3e-07 29.9 0.0 4.6 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 KFP04258.1 - 5.1e-18 63.4 6.9 0.0031 17.3 0.0 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFP04258.1 - 9.8e-15 53.4 7.2 3.8e-05 23.1 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP04258.1 - 7e-13 48.8 17.7 0.00046 20.7 0.1 5.5 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFP04258.1 - 5.7e-11 42.5 12.0 0.001 19.3 0.1 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFP04258.1 - 6.8e-11 41.9 12.7 0.00025 20.9 0.0 6.6 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFP04258.1 - 4.1e-09 36.2 17.7 0.16 12.7 0.0 7.6 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFP04258.1 - 1.1e-07 31.0 0.0 1.4 8.8 0.0 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP04258.1 - 9.7e-07 28.1 4.2 0.63 9.9 0.0 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP04258.1 - 1.9e-06 27.9 4.8 2.4 8.3 1.5 4.8 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFP04258.1 - 0.00011 21.4 0.6 0.21 10.6 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFP04258.1 - 0.00049 20.3 4.9 24 5.6 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFP04258.1 - 0.0039 17.2 4.9 3.6 7.7 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFP04258.1 - 0.012 16.0 13.9 13 6.5 0.1 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFP04258.1 - 0.025 14.7 1.7 14 6.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.12 KFP04258.1 - 0.041 14.1 9.2 0.2 11.9 0.0 4.1 4 2 1 5 5 5 0 Bacterial transcriptional activator domain TPR_9 PF13371.1 KFP04258.1 - 0.088 12.6 6.7 8.7 6.2 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP04258.1 - 0.11 12.4 9.2 25 4.9 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat DnaJ PF00226.26 KFP04259.1 - 5.3e-30 102.9 4.4 8.3e-30 102.3 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFP04259.1 - 2.5e-24 84.9 0.8 4.3e-22 77.8 0.0 2.5 3 0 0 3 3 3 2 DnaJ C terminal domain EF-hand_1 PF00036.27 KFP04260.1 - 3.7e-07 28.9 0.2 0.011 14.9 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFP04260.1 - 6e-07 28.8 0.3 0.012 15.4 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KFP04260.1 - 1.3e-06 28.4 1.4 0.018 15.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP04260.1 - 0.00027 20.4 0.2 0.85 9.2 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP04260.1 - 0.0017 17.5 0.2 1.5 8.3 0.1 2.8 2 0 0 2 2 2 2 EF hand PHD PF00628.24 KFP04260.1 - 1.6 8.4 14.5 0.4 10.3 7.2 2.2 2 1 0 2 2 2 0 PHD-finger RecR PF02132.10 KFP04260.1 - 3.8 7.0 7.0 20 4.7 3.6 2.7 2 0 0 2 2 2 0 RecR protein IL8 PF00048.15 KFP04261.1 - 9.6e-19 67.1 0.0 1.1e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ig_2 PF13895.1 KFP04262.1 - 3.7e-05 23.7 0.1 0.00037 20.5 0.0 2.3 3 0 0 3 3 3 1 Immunoglobulin domain EpoR_lig-bind PF09067.5 KFP04262.1 - 0.0059 16.5 0.2 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFP04263.1 - 1.9e-07 31.1 0.9 5.5e-07 29.6 0.1 2.2 2 0 0 2 2 2 1 Fibronectin type III domain Ig_2 PF13895.1 KFP04263.1 - 7.2e-06 26.0 2.5 8.9e-06 25.7 0.3 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFP04263.1 - 0.0033 17.5 4.9 0.0086 16.1 0.1 2.6 2 1 0 2 2 2 1 Immunoglobulin domain I-set PF07679.11 KFP04263.1 - 0.019 14.7 0.4 0.24 11.2 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin I-set domain PKD PF00801.15 KFP04263.1 - 0.039 13.6 1.0 0.13 12.0 0.0 2.4 3 0 0 3 3 3 0 PKD domain IL12p40_C PF10420.4 KFP04263.1 - 0.14 12.2 0.6 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus GalP_UDP_transf PF01087.17 KFP04265.1 - 2.9e-63 213.2 0.1 3.8e-63 212.8 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KFP04265.1 - 1.6e-31 109.0 0.2 6.2e-31 107.1 0.1 1.9 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KFP04265.1 - 0.0035 17.8 0.0 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 HIT domain ERG2_Sigma1R PF04622.7 KFP04266.1 - 1.5e-69 233.6 1.2 1.7e-69 233.4 0.9 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ARID PF01388.16 KFP04267.1 - 4.2e-24 84.2 0.0 7.5e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ketoacyl-synt PF00109.21 KFP04267.1 - 0.008 15.6 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PSP1 PF04468.7 KFP04267.1 - 0.058 13.3 0.1 2.1 8.4 0.0 2.8 2 1 1 3 3 3 0 PSP1 C-terminal conserved region FliC_SP PF12613.3 KFP04267.1 - 2.3 8.4 5.2 1.1 9.4 0.7 2.6 3 0 0 3 3 3 0 Flagellin structural protein Dynactin_p22 PF07426.6 KFP04268.1 - 1.4e-57 193.7 5.6 1.6e-57 193.6 3.9 1.0 1 0 0 1 1 1 1 Dynactin subunit p22 BCDHK_Adom3 PF10436.4 KFP04268.1 - 0.02 14.3 0.6 0.026 14.0 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Alba PF01918.16 KFP04269.1 - 2.3e-14 52.7 0.9 3.4e-14 52.1 0.6 1.2 1 0 0 1 1 1 1 Alba WD40 PF00400.27 KFP04270.1 - 1.3e-16 59.7 13.4 1.2e-06 28.1 1.8 6.6 6 1 1 7 7 7 5 WD domain, G-beta repeat FAM219A PF15260.1 KFP04271.1 - 1.6e-51 173.8 3.6 2.1e-51 173.4 2.5 1.1 1 0 0 1 1 1 1 Protein family FAM219A KGG PF10685.4 KFP04271.1 - 0.13 12.2 0.5 0.23 11.4 0.4 1.4 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif SMRP1 PF15181.1 KFP04272.1 - 4.9e-76 255.5 4.4 6e-76 255.2 3.1 1.0 1 0 0 1 1 1 1 Spermatid-specific manchette-related protein 1 Glyco_hydro_31 PF01055.21 KFP04273.1 - 4.4e-66 223.5 2.7 1.6e-63 215.0 1.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 KFP04273.1 - 0.00026 19.8 0.3 0.00068 18.4 0.2 1.6 1 1 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 KFP04275.1 - 6.9e-67 226.1 2.3 2.4e-64 217.8 1.6 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 KFP04275.1 - 0.0025 16.5 0.2 0.0047 15.6 0.2 1.4 1 0 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.17 KFP04277.1 - 1.7e-11 44.2 2.5 3.3e-11 43.2 1.7 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KFP04277.1 - 7e-06 26.3 2.4 0.007 16.7 0.1 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 KFP04277.1 - 0.0037 16.6 1.7 0.24 10.7 1.4 2.1 1 1 0 1 1 1 1 Cytolethal distending toxin A/C family NUDIX PF00293.23 KFP04278.1 - 5.5e-20 71.3 0.1 6.4e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain I-set PF07679.11 KFP04278.1 - 0.064 13.1 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Kinesin PF00225.18 KFP04279.1 - 3.7e-52 177.1 1.7 8.1e-52 175.9 1.2 1.6 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 KFP04279.1 - 0.0035 17.4 0.1 0.0088 16.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP04279.1 - 0.034 14.0 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) UBA PF00627.26 KFP04280.1 - 5.2e-10 38.8 1.5 5.1e-05 22.9 0.0 4.1 4 0 0 4 4 4 3 UBA/TS-N domain UBA_3 PF09288.5 KFP04280.1 - 0.0017 17.9 0.8 0.38 10.3 0.0 3.0 3 0 0 3 3 3 1 Fungal ubiquitin-associated domain HBS1_N PF08938.5 KFP04280.1 - 0.092 12.8 0.5 7.2 6.8 0.0 2.9 2 0 0 2 2 2 0 HBS1 N-terminus RNase_T PF00929.19 KFP04280.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Exonuclease MerR-DNA-bind PF09278.6 KFP04280.1 - 0.14 12.5 1.1 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 MerR, DNA binding DUF4337 PF14235.1 KFP04280.1 - 0.34 10.7 2.8 0.59 9.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MerR_1 PF13411.1 KFP04280.1 - 1.6 8.5 3.2 1.7 8.4 0.2 2.4 3 0 0 3 3 3 0 MerR HTH family regulatory protein WD40 PF00400.27 KFP04281.1 - 1.4e-09 37.4 1.5 2.5e-05 23.9 1.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat CNH PF00780.17 KFP04281.1 - 0.053 12.9 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 CNH domain Interferon PF00143.14 KFP04282.1 - 5.9e-27 94.5 0.2 6.6e-27 94.3 0.1 1.0 1 0 0 1 1 1 1 Interferon alpha/beta domain UQ_con PF00179.21 KFP04283.1 - 3.6e-32 110.7 0.3 4.6e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP04283.1 - 0.059 13.1 0.1 0.3 10.8 0.1 2.1 1 1 0 1 1 1 0 Prokaryotic E2 family B Nrap PF03813.9 KFP04284.1 - 3.9e-245 815.7 0.0 4.6e-245 815.5 0.0 1.0 1 0 0 1 1 1 1 Nrap protein MIP PF00230.15 KFP04285.1 - 3.3e-51 173.9 13.5 4.1e-51 173.6 9.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.15 KFP04286.1 - 3.3e-44 151.0 9.8 4.1e-44 150.7 6.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3172 PF11371.3 KFP04286.1 - 0.029 13.8 0.2 0.029 13.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) DUF1418 PF07214.7 KFP04286.1 - 0.088 12.4 1.9 3.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) RRM_1 PF00076.17 KFP04288.1 - 3.5e-37 125.8 0.0 2.2e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP04288.1 - 3.1e-27 94.3 0.1 1.1e-12 47.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP04288.1 - 2.8e-23 81.5 0.2 3e-10 39.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFP04288.1 - 0.00039 20.3 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA binding domain RRM_3 PF08777.6 KFP04288.1 - 0.0098 15.7 0.0 3 7.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFP04288.1 - 0.013 15.2 0.0 0.061 13.1 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KFP04289.1 - 0.014 15.2 0.1 0.026 14.3 0.1 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP04289.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Yae1_N PF09811.4 KFP04291.1 - 2.1e-12 46.3 31.2 1.7 8.2 21.6 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal PI3Ka PF00613.15 KFP04292.1 - 1.4e-58 197.0 1.8 2.8e-58 196.1 1.3 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFP04292.1 - 1.4e-51 175.2 0.0 4.4e-50 170.3 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KFP04292.1 - 1.1e-45 154.8 0.0 2.1e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.1 KFP04292.1 - 6.4e-05 22.1 0.0 0.00087 18.3 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4135) HEAT_2 PF13646.1 KFP04292.1 - 0.027 14.7 0.1 0.069 13.4 0.1 1.7 1 0 0 1 1 1 0 HEAT repeats Ras PF00071.17 KFP04294.1 - 2.4e-42 144.0 0.0 2.9e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP04294.1 - 2.2e-11 44.3 0.0 3.2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP04294.1 - 4.3e-05 22.8 0.0 6.3e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP04294.1 - 0.00053 19.4 0.0 0.00067 19.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KFP04294.1 - 0.0044 16.5 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein NADH_Oxid_Nqo15 PF11497.3 KFP04294.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 C2 PF00168.25 KFP04295.1 - 1.3e-46 156.3 0.1 2.1e-22 78.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain PTEN_C2 PF10409.4 KFP04295.1 - 0.0053 16.4 0.1 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein CEP76-C2 PF15627.1 KFP04295.1 - 0.073 12.5 0.1 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain Glypican PF01153.14 KFP04296.1 - 7.1e-222 737.9 6.4 8.1e-222 737.7 4.5 1.0 1 0 0 1 1 1 1 Glypican Sulfotransfer_2 PF03567.9 KFP04297.1 - 8.4e-12 45.3 0.1 8.4e-12 45.3 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase family PPV_E2_C PF00511.12 KFP04297.1 - 0.042 13.8 2.3 0.041 13.8 1.6 1.1 1 0 0 1 1 1 0 E2 (early) protein, C terminal SH3_9 PF14604.1 KFP04299.1 - 2.4e-09 36.6 0.0 4.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP04299.1 - 0.00015 21.0 0.0 0.00029 20.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain IncA PF04156.9 KFP04299.1 - 0.011 15.3 0.3 0.021 14.4 0.2 1.5 1 1 0 1 1 1 0 IncA protein NodZ PF05830.6 KFP04299.1 - 0.043 12.4 0.4 0.12 10.9 0.0 1.8 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) GrpE PF01025.14 KFP04299.1 - 0.12 11.8 0.3 0.27 10.7 0.2 1.6 1 0 0 1 1 1 0 GrpE C1q PF00386.16 KFP04300.1 - 1.1e-69 232.2 1.6 1.3e-37 128.6 0.1 2.1 2 0 0 2 2 2 2 C1q domain DUF3531 PF12049.3 KFP04300.1 - 0.019 14.6 0.2 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) MKT1_N PF12247.3 KFP04300.1 - 0.12 12.7 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication Complex1_30kDa PF00329.14 KFP04301.1 - 4.6e-33 113.5 0.1 6.3e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BTB PF00651.26 KFP04302.1 - 9.4e-26 89.9 2.2 1.8e-25 89.0 1.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 KFP04302.1 - 1.7e-17 62.7 3.3 6e-05 23.0 0.1 5.4 3 1 2 5 5 5 3 Kelch motif BACK PF07707.10 KFP04302.1 - 1.7e-09 37.3 0.6 1.9e-07 30.8 0.1 2.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFP04302.1 - 3.1e-07 29.9 0.4 0.04 13.6 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KFP04302.1 - 3.1e-07 29.8 6.4 0.058 12.9 0.0 5.1 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 KFP04302.1 - 6.5e-07 29.3 0.2 0.022 14.9 0.1 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP04302.1 - 0.0003 20.6 2.0 0.061 13.2 0.0 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 KFP04302.1 - 0.0032 17.1 0.2 1 9.2 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain DSPc PF00782.15 KFP04303.1 - 9.7e-17 60.8 0.0 1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFP04303.1 - 1.5e-05 24.4 0.2 4.4e-05 22.9 0.2 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KFP04303.1 - 0.00084 18.7 0.0 0.00086 18.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.1 KFP04303.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.1 KFP04303.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.5 2 0 0 2 2 2 0 Inositol hexakisphosphate RRM_1 PF00076.17 KFP04304.1 - 1.6e-51 171.7 0.0 4.2e-18 64.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP04304.1 - 1.5e-37 127.3 0.1 1.5e-11 44.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP04304.1 - 1.5e-29 101.6 0.5 1.5e-09 37.5 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFP04304.1 - 2.4e-06 27.4 0.0 0.4 10.7 0.0 3.5 3 0 0 3 3 3 3 RNA binding domain Nup35_RRM_2 PF14605.1 KFP04304.1 - 0.003 17.2 0.0 0.53 10.1 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KFP04304.1 - 0.062 13.0 0.2 5.6 6.7 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 Rapsyn_N PF10579.4 KFP04305.1 - 3.9e-44 148.3 0.3 5.7e-43 144.6 0.1 2.6 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_12 PF13424.1 KFP04305.1 - 8.4e-23 80.1 6.5 6.9e-09 35.5 0.0 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFP04305.1 - 7.3e-21 72.8 13.2 0.00015 21.2 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFP04305.1 - 1.9e-16 59.4 11.7 6.1e-06 25.7 0.6 5.5 2 2 2 5 5 5 4 TPR repeat TPR_2 PF07719.12 KFP04305.1 - 2.6e-15 55.0 12.3 0.0043 16.8 0.1 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFP04305.1 - 1.1e-10 40.4 13.3 0.071 12.9 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFP04305.1 - 1.8e-10 39.7 4.0 0.064 13.0 0.0 6.5 9 0 0 9 9 7 2 Tetratricopeptide repeat zf-RING_2 PF13639.1 KFP04305.1 - 4.1e-07 29.7 4.0 4.1e-07 29.7 2.8 3.4 4 0 0 4 4 4 1 Ring finger domain TPR_10 PF13374.1 KFP04305.1 - 7.9e-07 28.8 0.2 0.0049 16.7 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP04305.1 - 1e-06 28.9 0.7 5.2 7.4 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFP04305.1 - 1.9e-05 24.8 1.6 1.5 9.6 0.0 5.5 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFP04305.1 - 5.2e-05 23.7 0.1 18 6.1 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat SNAP PF14938.1 KFP04305.1 - 9.2e-05 21.7 0.2 0.33 10.0 0.0 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP DUF3856 PF12968.2 KFP04305.1 - 0.00015 21.6 2.2 0.64 9.8 0.0 3.8 3 1 1 4 4 3 2 Domain of Unknown Function (DUF3856) zf-RING_5 PF14634.1 KFP04305.1 - 0.00021 20.9 5.9 0.00021 20.9 4.1 3.7 4 0 0 4 4 3 1 zinc-RING finger domain TPR_6 PF13174.1 KFP04305.1 - 0.0057 17.0 4.7 2.3 8.8 0.1 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat zf-C3HC4 PF00097.20 KFP04305.1 - 0.0087 15.6 4.4 0.0087 15.6 3.1 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Fis1_TPR_C PF14853.1 KFP04305.1 - 0.011 15.5 4.7 0.33 10.8 0.0 4.2 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat zf-rbx1 PF12678.2 KFP04305.1 - 0.017 15.2 5.8 0.074 13.1 4.0 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger RPN7 PF10602.4 KFP04305.1 - 0.059 12.7 5.3 4.6 6.5 0.2 3.8 2 1 1 4 4 4 0 26S proteasome subunit RPN7 Apc5 PF12862.2 KFP04305.1 - 0.065 13.0 1.2 12 5.7 0.4 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 Apc3 PF12895.2 KFP04305.1 - 0.14 12.2 12.4 3.3 7.8 1.0 4.3 1 1 4 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFP04305.1 - 0.21 11.8 9.8 2.7 8.4 0.3 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 KFP04306.1 - 6.2e-42 142.9 0.0 1.4e-41 141.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFP04306.1 - 2e-06 27.5 0.4 1.4e-05 24.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFP04306.1 - 1.8e-05 24.7 0.1 0.001 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KFP04306.1 - 2.4e-05 23.4 0.1 8.9e-05 21.6 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFP04306.1 - 0.00013 22.1 0.4 0.018 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KFP04306.1 - 0.00015 21.6 0.0 0.00066 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFP04306.1 - 0.0021 17.0 0.0 0.0039 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 KFP04306.1 - 0.0023 17.1 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 KFP04306.1 - 0.0024 17.7 0.1 0.0049 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFP04306.1 - 0.0048 16.0 0.1 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KFP04306.1 - 0.0051 16.2 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFP04306.1 - 0.0058 16.3 0.2 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KFP04306.1 - 0.0066 16.0 0.1 0.53 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFP04306.1 - 0.007 17.1 0.3 0.086 13.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFP04306.1 - 0.022 13.8 0.1 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KFP04306.1 - 0.032 13.6 1.0 0.31 10.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFP04306.1 - 0.037 13.4 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KFP04306.1 - 0.04 13.4 1.2 0.067 12.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KFP04306.1 - 0.044 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3713 PF12506.3 KFP04306.1 - 0.054 13.5 1.9 0.45 10.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) KaiC PF06745.8 KFP04306.1 - 0.068 12.2 1.4 0.16 11.0 0.0 2.2 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 KFP04306.1 - 0.12 12.0 0.3 2.4 7.7 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Bacillus_HBL PF05791.6 KFP04306.1 - 0.13 11.6 1.5 0.43 9.9 0.5 2.3 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) RNA_helicase PF00910.17 KFP04306.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Claudin_2 PF13903.1 KFP04307.1 - 6.3e-15 55.2 5.5 7e-15 55.1 3.8 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP04307.1 - 0.016 14.8 8.3 0.022 14.3 5.8 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1056 PF06341.6 KFP04307.1 - 2 8.5 5.5 0.36 10.8 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) Zip PF02535.17 KFP04308.1 - 2e-55 188.0 1.4 2.6e-55 187.6 1.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ets PF00178.17 KFP04309.1 - 9.3e-30 102.6 4.4 1.4e-29 102.0 3.1 1.2 1 0 0 1 1 1 1 Ets-domain I-set PF07679.11 KFP04310.1 - 3.4e-106 347.3 12.6 5.6e-17 61.3 0.0 8.9 8 1 0 8 8 8 8 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP04310.1 - 4e-40 135.8 0.0 6.3e-08 32.6 0.0 8.4 7 1 1 8 8 8 7 Immunoglobulin domain fn3 PF00041.16 KFP04310.1 - 4.1e-40 135.7 0.0 1.3e-11 44.4 0.0 4.5 4 0 0 4 4 4 3 Fibronectin type III domain ig PF00047.20 KFP04310.1 - 2.7e-33 113.8 0.4 4.1e-05 23.6 0.0 8.1 7 1 0 7 7 7 6 Immunoglobulin domain V-set PF07686.12 KFP04310.1 - 3.4e-28 97.8 3.4 0.00087 19.1 0.1 9.4 7 2 1 8 8 8 6 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP04310.1 - 4.1e-17 62.4 0.0 0.00056 20.3 0.0 9.2 10 3 0 10 10 10 4 Immunoglobulin domain C2-set_2 PF08205.7 KFP04310.1 - 7.7e-11 41.7 0.0 0.027 14.3 0.0 6.4 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFP04310.1 - 8.1e-06 25.7 5.6 13 5.8 0.0 7.2 6 1 1 7 7 7 1 Immunoglobulin C1-set domain Herpes_gI PF01688.12 KFP04310.1 - 0.023 13.8 0.1 43 3.1 0.0 4.5 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein I Yae1_N PF09811.4 KFP04311.1 - 4.4e-14 51.7 39.5 6.1e+02 0.0 27.3 3.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DENN PF02141.16 KFP04312.1 - 5e-33 114.3 2.3 1.3e-32 113.0 1.6 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFP04312.1 - 6.1e-17 61.3 0.9 6.1e-17 61.3 0.6 2.1 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 KFP04312.1 - 2.3e-10 40.4 1.1 6.4e-10 38.9 0.1 2.4 2 0 0 2 2 2 1 dDENN domain Hormone_recep PF00104.25 KFP04313.1 - 3.2e-34 117.8 1.8 5.3e-34 117.1 1.2 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP04313.1 - 3.2e-19 68.9 6.6 5.9e-19 68.0 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) His_Phos_2 PF00328.17 KFP04314.1 - 3.8e-37 128.4 0.0 4.5e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tox-MPTase2 PF15638.1 KFP04314.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 WD40 PF00400.27 KFP04315.1 - 2.4e-13 49.3 11.3 2.5e-05 23.9 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 KFP04315.1 - 0.024 12.8 0.1 0.034 12.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ArfGap PF01412.13 KFP04316.1 - 4.8e-29 100.5 1.6 1.4e-28 99.0 1.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TGF_beta PF00019.15 KFP04318.1 - 1.1e-37 128.4 1.3 2.1e-37 127.5 0.9 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP04318.1 - 2.5e-17 62.9 0.3 4.8e-17 62.0 0.2 1.4 1 1 0 1 1 1 1 TGF-beta propeptide Yae1_N PF09811.4 KFP04319.1 - 1.2e-18 66.2 62.5 1.5e+04 -24.1 43.3 5.9 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-C2H2 PF00096.21 KFP04320.1 - 7.6e-19 66.8 30.2 0.00059 20.0 0.3 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP04320.1 - 2.2e-15 56.0 30.7 3e-07 30.4 1.0 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP04320.1 - 1.3e-06 28.3 35.4 0.02 15.1 0.1 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger Thiolase_N PF00108.18 KFP04321.1 - 9.4e-92 306.7 0.1 1.6e-91 305.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFP04321.1 - 8.2e-52 173.8 0.5 1.6e-51 172.8 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFP04321.1 - 0.0018 17.7 1.3 0.034 13.6 0.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain EzrA PF06160.7 KFP04322.1 - 0.00083 17.6 8.4 0.0011 17.2 5.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF342 PF03961.8 KFP04322.1 - 0.004 15.6 8.3 0.005 15.3 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Sipho_Gp157 PF05565.6 KFP04322.1 - 0.017 14.7 5.9 0.031 13.8 4.1 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 APG6 PF04111.7 KFP04322.1 - 0.019 13.9 16.2 0.023 13.7 11.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IZUMO PF15005.1 KFP04322.1 - 0.02 14.9 4.5 0.035 14.1 3.1 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion Prefoldin PF02996.12 KFP04322.1 - 0.042 13.5 7.7 0.55 9.8 1.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit GAS PF13851.1 KFP04322.1 - 0.06 12.5 20.8 1.3 8.1 14.3 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 KFP04322.1 - 0.099 12.6 15.4 0.99 9.4 5.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor Acetate_kinase PF00871.12 KFP04322.1 - 0.1 11.1 0.1 0.15 10.5 0.0 1.3 1 1 0 1 1 1 0 Acetokinase family RdRP_4 PF02123.11 KFP04322.1 - 0.1 11.2 2.9 0.13 10.9 2.0 1.0 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase DUF2890 PF11081.3 KFP04322.1 - 0.11 12.4 4.2 0.16 12.0 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2492 PF10678.4 KFP04322.1 - 0.14 12.2 1.3 0.24 11.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) V_ATPase_I PF01496.14 KFP04322.1 - 0.16 9.7 10.4 0.21 9.4 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2508 PF10704.4 KFP04322.1 - 0.3 11.2 9.0 0.11 12.7 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) AAA_13 PF13166.1 KFP04322.1 - 0.32 9.4 7.5 0.38 9.1 5.2 1.1 1 0 0 1 1 1 0 AAA domain Lectin_N PF03954.9 KFP04322.1 - 0.35 10.2 3.8 0.76 9.1 2.6 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.7 KFP04322.1 - 0.36 11.0 7.2 3.9 7.8 1.0 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Erp_C PF06780.6 KFP04322.1 - 0.37 10.6 6.0 0.71 9.7 0.6 2.2 2 0 0 2 2 2 0 Erp protein C-terminus YajC PF02699.10 KFP04322.1 - 0.43 10.2 0.0 0.43 10.2 0.0 2.0 2 1 0 2 2 1 0 Preprotein translocase subunit TMF_TATA_bd PF12325.3 KFP04322.1 - 0.48 10.1 19.8 0.4 10.4 5.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GABP-alpha PF11620.3 KFP04322.1 - 0.48 10.4 6.9 5.7 7.0 0.6 2.2 1 1 1 2 2 2 0 GA-binding protein alpha chain DUF3763 PF12592.3 KFP04322.1 - 0.55 9.9 9.0 1.2 8.7 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) IncA PF04156.9 KFP04322.1 - 0.58 9.7 20.2 6.3 6.3 14.0 2.0 1 1 0 1 1 1 0 IncA protein DUF4407 PF14362.1 KFP04322.1 - 0.7 8.7 7.7 1.5 7.7 5.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MRP-S27 PF10037.4 KFP04322.1 - 0.79 8.5 10.9 0.9 8.3 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 PilJ PF13675.1 KFP04322.1 - 0.86 9.9 5.9 2.1 8.7 4.1 1.7 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term SEO_N PF14576.1 KFP04322.1 - 1 8.6 6.2 0.22 10.7 1.4 1.8 1 1 1 2 2 2 0 Sieve element occlusion N-terminus DivIC PF04977.10 KFP04322.1 - 1.2 8.7 13.5 1.5 8.3 2.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.17 KFP04322.1 - 1.4 8.9 13.2 35 4.4 9.1 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2408 PF10303.4 KFP04322.1 - 1.5 8.9 8.3 1.7 8.7 5.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CENP-F_leu_zip PF10473.4 KFP04322.1 - 1.6 8.6 21.9 3.8 7.3 15.2 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 KFP04322.1 - 1.8 8.5 9.7 4.9 7.1 0.8 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Striatin PF08232.7 KFP04322.1 - 1.9 8.7 15.2 0.75 10.1 4.2 2.1 1 1 1 2 2 2 0 Striatin family CENP-H PF05837.7 KFP04322.1 - 2 8.6 12.6 0.45 10.7 2.7 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF479 PF04336.7 KFP04322.1 - 3 7.9 6.8 7.4 6.7 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF479 NUDE_C PF04880.8 KFP04322.1 - 4.1 7.7 7.3 7.8 6.8 5.0 1.6 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region CENP-Q PF13094.1 KFP04322.1 - 4.3 7.3 23.3 12 5.8 4.2 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIVA PF05103.8 KFP04322.1 - 5 7.1 16.4 2 8.4 4.4 2.1 1 1 1 2 2 2 0 DivIVA protein Syntaxin-6_N PF09177.6 KFP04322.1 - 6 7.3 9.2 7.4 7.0 3.8 2.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TBPIP PF07106.8 KFP04322.1 - 6.4 6.3 15.6 30 4.1 10.7 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 KFP04322.1 - 9.9 5.5 16.4 4.6 6.6 2.1 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Bap31 PF05529.7 KFP04322.1 - 10 5.5 11.7 3.5 7.0 0.3 2.2 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like IL7 PF01415.11 KFP04325.1 - 0.017 14.7 2.2 0.025 14.2 1.5 1.3 1 0 0 1 1 1 0 Interleukin 7/9 family F-box-like PF12937.2 KFP04326.1 - 5e-11 42.1 1.8 1.2e-10 40.8 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFP04326.1 - 3.5e-09 36.0 2.4 4.5e-09 35.7 0.4 2.2 2 0 0 2 2 2 1 F-box domain Peptidase_M23 PF01551.17 KFP04327.1 - 3e-10 40.0 0.4 0.00018 21.4 0.0 3.0 2 1 0 2 2 2 2 Peptidase family M23 zf-A20 PF01754.11 KFP04327.1 - 0.078 12.5 7.8 0.5 9.9 1.0 2.9 2 0 0 2 2 2 0 A20-like zinc finger PRRSV_2b PF07069.6 KFP04327.1 - 0.16 12.2 0.3 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Fasciclin PF02469.17 KFP04328.1 - 1.1e-102 339.0 3.3 1.1e-32 112.6 0.2 4.2 4 0 0 4 4 4 4 Fasciclin domain EMI PF07546.8 KFP04328.1 - 1.6 9.2 6.7 5.1 7.6 4.7 1.8 1 1 0 1 1 1 0 EMI domain MH2 PF03166.9 KFP04329.1 - 8.2e-79 263.6 0.2 1.1e-78 263.2 0.2 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFP04329.1 - 2.1e-42 143.2 0.3 4.9e-42 142.1 0.2 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFP04329.1 - 2.7e-07 30.3 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 Ion_trans PF00520.26 KFP04330.1 - 2.3e-27 95.5 34.9 8.9e-19 67.5 19.6 2.5 2 0 0 2 2 2 2 Ion transport protein Yae1_N PF09811.4 KFP04331.1 - 1.8e-16 59.3 56.3 2.6 7.6 0.7 5.6 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Cyclin_N PF00134.18 KFP04332.1 - 1.3e-37 128.1 2.4 1.3e-37 128.1 1.6 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP04332.1 - 2.7e-22 78.8 2.1 1.3e-21 76.6 0.3 2.4 2 1 1 3 3 3 1 Cyclin, C-terminal domain Urb2 PF10441.4 KFP04332.1 - 0.072 12.6 0.6 0.16 11.5 0.4 1.6 1 1 0 1 1 1 0 Urb2/Npa2 family Yae1_N PF09811.4 KFP04333.1 - 3.2e-10 39.3 6.7 4.7e-10 38.8 4.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FGF PF00167.13 KFP04334.1 - 1.7e-18 66.5 0.0 2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.13 KFP04335.1 - 2.8e-32 111.0 0.0 3.3e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor FGF PF00167.13 KFP04336.1 - 7.5e-34 116.1 0.1 8.9e-34 115.8 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Anoctamin PF04547.7 KFP04337.1 - 6.3e-137 456.9 4.4 1.4e-79 267.8 0.0 2.2 1 1 1 2 2 2 2 Calcium-activated chloride channel Death PF00531.17 KFP04338.1 - 4.2e-18 64.9 0.5 2.4e-16 59.2 0.2 2.2 2 0 0 2 2 2 2 Death domain DED PF01335.16 KFP04338.1 - 8.1e-17 61.1 1.6 1.4e-16 60.3 1.1 1.4 1 0 0 1 1 1 1 Death effector domain SAM_1 PF00536.25 KFP04339.1 - 1.8e-23 82.4 0.3 1e-11 44.8 0.0 3.8 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP04339.1 - 4.8e-22 77.5 0.2 4.6e-08 32.7 0.0 3.6 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) Yae1_N PF09811.4 KFP04340.1 - 2.5e-15 55.7 36.1 0.00066 19.1 5.0 4.1 1 1 1 2 2 2 2 Essential protein Yae1, N terminal HS1_rep PF02218.10 KFP04341.1 - 4.9e-114 371.9 68.5 2.7e-22 78.3 5.9 6.9 7 0 0 7 7 7 6 Repeat in HS1/Cortactin SH3_9 PF14604.1 KFP04341.1 - 8.7e-18 63.6 0.2 1.9e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP04341.1 - 1.1e-16 59.9 0.2 2.8e-16 58.6 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP04341.1 - 1e-10 40.8 0.0 3e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain TMEM210 PF15195.1 KFP04341.1 - 2.4e-06 27.6 2.0 16 5.6 0.0 5.9 1 1 5 6 6 6 1 TMEM210 family AMP-binding_C_2 PF14535.1 KFP04341.1 - 0.01 15.8 2.5 0.13 12.3 0.4 3.1 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF4551 PF15087.1 KFP04341.1 - 3.5 5.8 7.6 4.7 5.4 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Endonuc-dimeris PF09124.5 KFP04341.1 - 3.6 7.2 9.4 17 5.0 0.3 3.7 3 0 0 3 3 3 0 T4 recombination endonuclease VII, dimerisation Ank_2 PF12796.2 KFP04342.1 - 3.8e-29 100.8 11.1 4.1e-14 52.6 0.8 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP04342.1 - 2.3e-26 91.6 2.2 3.2e-09 37.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFP04342.1 - 1.5e-21 75.0 6.2 4e-05 23.2 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat SAM_1 PF00536.25 KFP04342.1 - 1.3e-19 70.1 0.1 3.3e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP04342.1 - 5.9e-18 64.4 0.2 1.3e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.1 KFP04342.1 - 4.4e-16 58.5 8.9 1.3e-06 28.4 0.1 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP04342.1 - 1.1e-15 56.0 5.2 0.043 14.0 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat SH3_2 PF07653.12 KFP04342.1 - 5e-14 51.5 0.6 1.1e-13 50.3 0.4 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFP04342.1 - 1.3e-10 40.7 0.1 3.1e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.19 KFP04342.1 - 1.7e-08 34.4 0.0 6.5e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SH3_1 PF00018.23 KFP04342.1 - 3.6e-06 26.2 0.0 7.6e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_PNT PF02198.11 KFP04342.1 - 0.17 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain UPAR_LY6 PF00021.16 KFP04343.1 - 4e-05 23.9 14.0 7e-05 23.1 9.7 1.4 1 0 0 1 1 1 1 u-PAR/Ly-6 domain Activin_recp PF01064.18 KFP04343.1 - 0.77 10.4 14.7 1.7 9.3 10.2 1.5 1 1 0 1 1 1 0 Activin types I and II receptor domain DUF525 PF04379.9 KFP04344.1 - 5.4e-28 96.7 0.1 1.7e-27 95.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF525) SMI1_KNR4 PF09346.5 KFP04344.1 - 1.7e-06 28.1 0.0 4.9e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Elongin_A PF06881.6 KFP04344.1 - 0.053 13.8 1.0 0.1 12.9 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A LIM PF00412.17 KFP04345.1 - 1.9e-28 98.3 21.3 1.6e-15 56.9 6.3 2.0 2 0 0 2 2 2 2 LIM domain C1_4 PF07975.7 KFP04345.1 - 0.012 15.5 5.7 0.012 15.5 4.0 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain Vps39_2 PF10367.4 KFP04345.1 - 0.055 13.6 0.8 0.055 13.6 0.6 3.3 1 1 2 4 4 4 0 Vacuolar sorting protein 39 domain 2 Churchill PF06573.6 KFP04345.1 - 0.57 10.1 10.1 0.18 11.7 1.6 2.2 1 1 1 2 2 2 0 Churchill protein DiS_P_DiS PF06750.8 KFP04345.1 - 0.98 9.2 5.5 11 5.9 2.5 2.8 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain GrpE PF01025.14 KFP04346.1 - 0.048 13.1 4.7 0.064 12.7 3.2 1.3 1 0 0 1 1 1 0 GrpE DUF1140 PF06600.6 KFP04346.1 - 0.071 13.2 1.6 0.25 11.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1140) DUF3608 PF12257.3 KFP04346.1 - 0.12 11.2 0.3 0.14 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) OmpH PF03938.9 KFP04346.1 - 1 9.2 8.1 1.2 9.0 5.3 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) GNAT_acetyltr_2 PF13718.1 KFP04347.1 - 6.1e-75 250.8 0.0 1.7e-74 249.3 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KFP04347.1 - 9.6e-66 220.7 0.0 3e-65 219.1 0.0 1.9 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 KFP04347.1 - 1.1e-43 146.8 0.2 2.8e-43 145.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KFP04347.1 - 1.8e-33 114.6 0.8 1.8e-33 114.6 0.6 2.5 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KFP04347.1 - 3.2e-05 23.9 0.1 0.00029 20.9 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFP04347.1 - 0.00047 20.1 0.0 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Ank_2 PF12796.2 KFP04348.1 - 5.7e-34 116.3 5.1 6e-18 64.9 0.1 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP04348.1 - 2.7e-24 83.6 5.8 2.3e-08 33.4 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat BTB PF00651.26 KFP04348.1 - 9.4e-24 83.5 0.7 2.5e-23 82.2 0.4 1.8 1 1 0 1 1 1 1 BTB/POZ domain Ank_3 PF13606.1 KFP04348.1 - 1.8e-17 61.6 1.4 9e-05 22.3 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KFP04348.1 - 5.3e-17 61.8 0.1 6.4e-05 23.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP04348.1 - 1.7e-13 50.3 3.0 0.00046 20.3 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) BACK PF07707.10 KFP04348.1 - 0.00065 19.5 0.3 0.0026 17.5 0.1 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Catalase PF00199.14 KFP04349.1 - 9.7e-191 633.4 0.0 1.3e-190 633.0 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFP04349.1 - 1.1e-19 69.9 1.1 4.1e-19 68.1 0.3 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive FA_desaturase PF00487.19 KFP04350.1 - 4.2e-36 124.7 24.5 4.2e-36 124.7 17.0 1.5 1 1 1 2 2 2 1 Fatty acid desaturase FA_desaturase PF00487.19 KFP04351.1 - 1.6e-09 37.6 2.6 1.7e-09 37.5 1.8 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFP04352.1 - 4.2e-18 64.9 0.1 8.4e-18 63.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 KFP04352.1 - 3.2e-13 49.7 3.4 3.2e-13 49.7 2.4 1.9 1 1 1 2 2 2 1 Fatty acid desaturase FA_desaturase PF00487.19 KFP04353.1 - 1.9e-25 89.7 26.6 1.9e-25 89.7 18.4 1.6 1 1 1 2 2 2 2 Fatty acid desaturase FA_desaturase PF00487.19 KFP04354.1 - 4.1e-30 105.0 25.7 6.4e-30 104.4 15.1 2.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFP04354.1 - 4.4e-22 77.6 0.0 9e-22 76.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CHDNT PF08073.7 KFP04354.1 - 0.0081 15.8 0.0 0.038 13.6 0.0 2.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain EpuA PF11772.3 KFP04354.1 - 0.016 14.6 0.3 0.07 12.5 0.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Sec2p PF06428.6 KFP04355.1 - 2e-26 91.7 6.7 4.6e-26 90.6 4.6 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p DUF4407 PF14362.1 KFP04355.1 - 0.074 11.9 4.0 0.1 11.5 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cob_adeno_trans PF01923.13 KFP04355.1 - 0.19 11.4 4.9 0.5 10.1 1.1 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase IATP PF04568.7 KFP04355.1 - 0.26 11.3 8.7 0.26 11.3 4.9 1.8 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP APG6 PF04111.7 KFP04355.1 - 0.37 9.7 15.3 0.53 9.2 10.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFP04355.1 - 0.53 9.8 12.2 0.98 8.9 8.5 1.4 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 KFP04355.1 - 0.65 9.8 19.4 1.3 8.8 13.4 1.5 1 1 0 1 1 1 0 Tropomyosin like Borrelia_P83 PF05262.6 KFP04355.1 - 0.87 7.7 7.9 1.2 7.3 5.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Spc7 PF08317.6 KFP04355.1 - 1.3 7.5 12.5 2.2 6.8 8.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.10 KFP04355.1 - 1.4 8.5 11.8 2.6 7.6 8.1 1.5 1 0 0 1 1 1 0 Mnd1 family HSP70 PF00012.15 KFP04355.1 - 1.6 6.5 9.1 2.2 6.0 6.3 1.1 1 0 0 1 1 1 0 Hsp70 protein Atg14 PF10186.4 KFP04355.1 - 1.8 7.4 10.1 2.8 6.7 6.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 KFP04355.1 - 2.8 6.2 7.4 3.8 5.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) XhlA PF10779.4 KFP04355.1 - 6.8 6.6 11.5 0.88 9.5 2.6 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Bestrophin PF01062.16 KFP04356.1 - 2.2e-104 348.5 4.3 2.6e-104 348.3 3.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ferritin PF00210.19 KFP04357.1 - 1.2e-37 128.7 3.4 1.5e-37 128.4 2.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 KFP04357.1 - 0.0078 16.5 1.1 0.011 16.0 0.8 1.3 1 1 0 1 1 1 1 Rubrerythrin FCH PF00611.18 KFP04357.1 - 0.022 14.9 1.6 0.051 13.7 1.1 1.7 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Ferritin PF00210.19 KFP04358.1 - 2.9e-36 124.3 2.9 3.3e-36 124.1 2.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 KFP04358.1 - 0.0061 16.8 1.5 0.0085 16.4 1.0 1.4 1 1 0 1 1 1 1 Rubrerythrin DUF1215 PF06744.7 KFP04358.1 - 0.025 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) FCH PF00611.18 KFP04358.1 - 0.035 14.2 1.8 0.061 13.5 1.2 1.5 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain 7tm_4 PF13853.1 KFP04359.1 - 3.5e-42 143.6 15.3 3.5e-42 143.6 10.6 2.2 3 0 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFP04359.1 - 1.6e-34 119.2 25.0 1.6e-34 119.2 17.3 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04359.1 - 0.00013 21.2 11.9 0.00013 21.2 8.2 2.3 1 1 1 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx DUF1772 PF08592.6 KFP04359.1 - 8.7 6.0 14.5 0.24 11.1 2.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) 7tm_1 PF00001.16 KFP04360.1 - 1.9e-19 69.8 1.0 1.9e-19 69.8 0.7 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04360.1 - 4.7e-05 22.6 2.0 5.8e-05 22.3 1.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srbc PF10316.4 KFP04360.1 - 0.051 12.8 3.1 0.064 12.5 2.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srbc LysE PF01810.13 KFP04360.1 - 0.14 11.4 1.9 0.16 11.2 0.3 1.7 2 0 0 2 2 2 0 LysE type translocator DUF2842 PF11003.3 KFP04360.1 - 6.2 6.7 6.6 3.5 7.5 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2842) 7tm_4 PF13853.1 KFP04361.1 - 1.1e-46 158.2 8.7 1.1e-46 158.2 6.0 2.2 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP04361.1 - 1.5e-31 109.4 16.9 2.5e-31 108.7 11.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04361.1 - 3.2e-06 26.5 14.2 5.1e-06 25.8 9.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP04361.1 - 0.21 10.6 12.1 0.16 11.0 7.4 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.1 KFP04362.1 - 1.3e-36 125.4 15.0 1.3e-36 125.4 10.4 2.3 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP04362.1 - 6.1e-29 100.9 24.4 8.6e-29 100.4 16.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04362.1 - 3e-05 23.3 22.1 0.00013 21.1 15.2 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFP04363.1 - 4.3e-39 133.5 13.8 4.3e-39 133.5 9.6 2.4 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP04363.1 - 1.3e-26 93.2 21.8 1.9e-26 92.7 15.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04363.1 - 2.4e-06 26.9 20.8 4.7e-06 25.9 14.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFP04364.1 - 3e-36 124.3 14.1 3e-36 124.3 9.8 2.7 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFP04364.1 - 4.2e-30 104.7 21.3 6e-30 104.2 14.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04364.1 - 8e-05 21.9 21.1 0.00036 19.7 14.6 2.2 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_1 PF00001.16 KFP04365.1 - 6.8e-09 35.2 14.8 3.5e-08 32.9 10.3 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srbc PF10316.4 KFP04365.1 - 0.00029 20.1 0.8 0.00029 20.1 0.5 2.5 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc TOM_sub5 PF15178.1 KFP04366.1 - 2.1e-26 91.3 0.8 2.3e-26 91.2 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit TOM5 homolog DUF1077 PF06417.7 KFP04367.1 - 6.4e-15 54.5 0.6 7.1e-15 54.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DnaJ PF00226.26 KFP04370.1 - 2.7e-22 78.2 0.3 4.3e-22 77.6 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFP04370.1 - 2.7e-16 59.2 0.1 2.6e-12 46.4 0.0 3.0 3 1 1 4 4 4 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFP04370.1 - 1.1e-11 44.6 20.1 1.9e-11 43.8 13.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFP04370.1 - 0.0059 16.2 9.9 0.055 13.1 0.8 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 KFP04370.1 - 2.8 8.3 7.3 5.9 7.2 5.0 1.6 1 0 0 1 1 1 0 Cytochrome c3 Filament PF00038.16 KFP04371.1 - 4.4e-24 85.5 28.3 5.4e-24 85.2 19.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF2681 PF10883.3 KFP04371.1 - 0.24 11.6 0.1 0.24 11.6 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2681) Myosin_tail_1 PF01576.14 KFP04371.1 - 0.26 8.9 36.3 0.74 7.4 25.0 1.9 1 1 0 1 1 1 0 Myosin tail Phlebovirus_NSM PF07246.6 KFP04371.1 - 0.39 9.8 9.5 1.4 7.9 0.0 2.8 3 0 0 3 3 3 0 Phlebovirus nonstructural protein NS-M YlqD PF11068.3 KFP04371.1 - 6.5 6.7 23.2 6.7 6.7 0.0 4.1 2 1 2 4 4 4 0 YlqD protein Ammonium_transp PF00909.16 KFP04372.1 - 3.1e-48 164.2 16.4 3.6e-48 164.0 11.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Peptidase_M14 PF00246.19 KFP04373.1 - 2.3e-82 276.7 0.0 2.8e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFP04373.1 - 2.8e-24 84.5 0.4 7e-24 83.3 0.3 1.7 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Phage_min_tail PF05939.8 KFP04373.1 - 0.035 14.0 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Phage minor tail protein Rhodanese PF00581.15 KFP04374.1 - 0.00052 20.3 0.0 0.0029 17.9 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Abhydrolase_6 PF12697.2 KFP04375.1 - 2.2e-22 80.0 0.0 2.5e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP04375.1 - 1.7e-08 34.3 0.0 2.9e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFP04375.1 - 3.8e-05 23.4 0.0 0.0001 22.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 KFP04375.1 - 0.0061 15.4 0.0 0.0086 14.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) COP-gamma_platf PF08752.5 KFP04376.1 - 2.3e-20 72.9 0.1 3.4e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Adaptin_N PF01602.15 KFP04376.1 - 0.072 11.3 0.0 0.098 10.9 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Laminin_G_2 PF02210.19 KFP04378.1 - 7e-24 84.2 0.2 2.9e-18 66.1 0.1 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFP04378.1 - 1.1e-14 54.5 0.0 1.2e-10 41.5 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain DUF4154 PF13689.1 KFP04378.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) F5_F8_type_C PF00754.20 KFP04379.1 - 4.2e-17 62.2 2.3 4.6e-17 62.0 1.6 1.0 1 0 0 1 1 1 1 F5/8 type C domain Claudin_2 PF13903.1 KFP04381.1 - 8.1e-19 67.9 0.0 1.4e-18 67.2 0.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP04381.1 - 2e-09 37.3 5.0 7.4e-07 28.9 0.8 2.3 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family TMEM190 PF15431.1 KFP04381.1 - 0.13 12.2 0.2 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 190 Phospholip_A2_1 PF00068.14 KFP04382.1 - 4.9e-34 117.0 15.8 5.8e-34 116.7 11.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFP04382.1 - 0.0032 17.2 0.1 0.0066 16.2 0.0 1.6 2 0 0 2 2 2 1 Parvovirus coat protein VP1 zf-DHHC PF01529.15 KFP04383.1 - 6.4e-35 120.0 1.3 6.4e-35 120.0 0.9 2.2 1 1 1 2 2 2 2 DHHC palmitoyltransferase TGT PF01702.13 KFP04385.1 - 4e-69 232.5 0.0 4.7e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase 7tm_1 PF00001.16 KFP04386.1 - 3e-87 292.0 11.8 4.7e-87 291.3 8.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04386.1 - 5.5e-12 45.3 14.5 4.6e-09 35.8 9.6 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP04386.1 - 6.4e-05 22.2 21.1 0.00029 20.0 10.9 2.6 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFP04386.1 - 0.002 17.2 16.1 0.0028 16.8 10.4 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Cytochrom_NNT PF03264.9 KFP04386.1 - 0.58 9.5 3.0 3.4 7.0 0.0 2.8 3 0 0 3 3 3 0 NapC/NirT cytochrome c family, N-terminal region BTB PF00651.26 KFP04387.1 - 3.8e-24 84.8 0.1 1.1e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP04387.1 - 4.4e-22 77.2 37.6 2.1e-06 27.7 1.9 6.9 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04387.1 - 9.5e-22 75.9 41.3 1.9e-06 27.8 1.5 6.2 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04387.1 - 2.3e-15 55.6 32.0 0.00034 20.7 1.0 5.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 KFP04387.1 - 2.3e-07 30.7 33.4 0.0025 17.9 1.0 5.9 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP04387.1 - 6e-07 29.1 19.5 0.01 15.7 0.2 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFP04387.1 - 8.9e-06 25.2 6.3 0.46 10.2 0.0 4.5 4 0 0 4 4 4 3 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFP04387.1 - 0.00021 21.3 20.6 0.073 13.2 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP04387.1 - 0.0024 17.9 24.1 0.027 14.5 6.7 4.4 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) BolA PF01722.13 KFP04387.1 - 0.022 14.7 1.4 0.91 9.5 0.2 3.3 3 1 0 3 3 3 0 BolA-like protein zf-Di19 PF05605.7 KFP04387.1 - 0.095 12.8 22.8 1.8 8.7 2.5 4.1 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-Sec23_Sec24 PF04810.10 KFP04387.1 - 1.1 8.8 10.4 1.9 8.1 0.0 4.3 5 0 0 5 5 5 0 Sec23/Sec24 zinc finger DUF2225 PF09986.4 KFP04387.1 - 1.5 8.2 13.0 1 8.7 0.2 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Endonuclease_7 PF02945.10 KFP04387.1 - 3.6 7.3 13.0 1.3 8.7 3.1 3.6 1 1 1 2 2 2 0 Recombination endonuclease VII Neuromodulin PF06614.6 KFP04389.1 - 1.6e-62 210.5 67.2 1.6e-62 210.5 46.6 1.7 2 1 0 2 2 2 1 Neuromodulin Neuromodulin_N PF10580.4 KFP04389.1 - 2.2e-11 43.1 7.2 2.2e-11 43.1 5.0 2.3 2 1 0 2 2 2 1 Gap junction protein N-terminal region IQ PF00612.22 KFP04389.1 - 2.7e-06 26.5 0.4 4.2e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif I-set PF07679.11 KFP04390.1 - 5.2e-40 135.2 1.5 4.4e-16 58.5 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP04390.1 - 1e-31 108.8 1.4 5.3e-13 48.9 0.0 3.1 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP04390.1 - 8.9e-22 77.3 0.6 1.6e-09 38.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP04390.1 - 4.6e-20 71.5 0.2 4e-08 33.2 0.0 3.5 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP04390.1 - 1.9e-15 56.7 2.3 0.00049 19.9 0.1 4.7 2 2 1 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP04390.1 - 3.2e-07 30.1 1.5 0.017 14.9 0.0 2.7 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 KFP04390.1 - 0.00014 21.6 0.7 0.24 11.1 0.1 3.2 2 1 1 3 3 3 2 CD47 immunoglobulin-like domain Sp38 PF07354.7 KFP04390.1 - 0.039 12.5 0.2 0.13 10.8 0.0 1.9 3 0 0 3 3 3 0 Zona-pellucida-binding protein (Sp38) C2-set PF05790.10 KFP04390.1 - 0.048 13.6 0.1 16 5.5 0.0 3.7 4 0 0 4 4 4 0 Immunoglobulin C2-set domain RNA_POL_M_15KD PF02150.11 KFP04392.1 - 1.3e-12 47.1 2.3 2.4e-12 46.2 1.6 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit FerA PF08165.6 KFP04392.1 - 0.11 12.1 0.1 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 FerA (NUC095) domain Pkinase PF00069.20 KFP04393.1 - 7.2e-75 251.4 0.0 9.4e-75 251.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04393.1 - 8.8e-37 126.5 0.0 1.3e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP04393.1 - 2.9e-10 39.6 0.0 2.4e-09 36.5 0.0 2.4 3 0 0 3 3 3 1 Kinase-like PH PF00169.24 KFP04393.1 - 9e-10 38.6 3.2 0.00038 20.6 0.1 2.9 3 0 0 3 3 3 2 PH domain Pkinase_C PF00433.19 KFP04393.1 - 7.6e-08 32.7 0.4 1.4e-07 31.9 0.3 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.1 KFP04393.1 - 0.00052 20.2 1.0 0.097 12.9 0.2 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Seadorna_VP7 PF07387.6 KFP04393.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1546 PF07571.8 KFP04394.1 - 3.4e-21 75.1 0.0 6.3e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) CCDC-167 PF15188.1 KFP04395.1 - 2.1 8.3 5.7 6.7 6.7 3.9 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 OmpH PF03938.9 KFP04395.1 - 3.2 7.6 8.2 3.8 7.4 5.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-H2C2_2 PF13465.1 KFP04396.1 - 7.6e-32 108.0 47.4 5.6e-09 35.8 1.6 6.2 6 1 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04396.1 - 1.5e-26 91.0 41.8 3.4e-06 27.0 4.0 6.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04396.1 - 2e-15 55.8 42.2 0.00018 21.5 1.7 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP04396.1 - 2.1e-10 40.1 31.9 0.0072 16.1 0.7 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFP04396.1 - 8.7e-08 31.9 17.9 0.035 14.0 1.7 4.9 3 1 1 4 4 4 3 Zinc ribbon domain zf-RING_3 PF14369.1 KFP04396.1 - 3.2e-07 30.2 10.5 0.02 14.9 0.1 4.5 4 0 0 4 4 4 2 zinc-finger XPA_N PF01286.13 KFP04396.1 - 4e-06 26.3 7.6 1.7 8.3 0.0 5.1 5 0 0 5 5 5 1 XPA protein N-terminal GAGA PF09237.6 KFP04396.1 - 1.7e-05 24.3 0.5 0.12 11.9 0.0 2.5 1 1 1 2 2 2 2 GAGA factor zf-C2H2_jaz PF12171.3 KFP04396.1 - 2.8e-05 24.1 20.5 0.037 14.1 0.6 5.3 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.7 KFP04396.1 - 0.00018 21.5 15.8 0.00048 20.2 4.1 2.4 1 1 1 2 2 2 1 CHY zinc finger zf-Di19 PF05605.7 KFP04396.1 - 0.00035 20.6 18.8 0.0034 17.4 1.5 4.1 2 1 1 4 4 3 1 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.1 KFP04396.1 - 0.00035 20.1 15.8 0.54 9.9 0.2 4.9 4 1 0 4 4 4 2 Probable zinc-binding domain DZR PF12773.2 KFP04396.1 - 0.00059 19.6 14.1 0.014 15.2 2.5 3.4 2 1 1 3 3 3 2 Double zinc ribbon Prok-RING_1 PF14446.1 KFP04396.1 - 0.0016 18.0 9.0 5.8 6.7 0.1 4.7 4 1 1 5 5 5 0 Prokaryotic RING finger family 1 zf-C2HC_2 PF13913.1 KFP04396.1 - 0.0044 16.6 0.7 0.18 11.5 0.1 4.7 5 0 0 5 5 4 2 zinc-finger of a C2HC-type zf-HIT PF04438.11 KFP04396.1 - 0.0051 16.4 14.6 0.54 9.9 0.2 4.4 4 0 0 4 4 4 2 HIT zinc finger zf-AN1 PF01428.11 KFP04396.1 - 0.0069 16.2 14.1 6.9 6.6 0.3 4.6 4 0 0 4 4 4 0 AN1-like Zinc finger CpXC PF14353.1 KFP04396.1 - 0.0079 16.1 13.0 4.7 7.1 0.1 4.4 2 1 2 4 4 4 0 CpXC protein zf-ribbon_3 PF13248.1 KFP04396.1 - 0.011 14.9 17.0 0.32 10.2 0.1 4.7 5 0 0 5 5 5 0 zinc-ribbon domain Evr1_Alr PF04777.8 KFP04396.1 - 0.012 15.5 15.0 0.58 10.0 0.7 3.7 1 1 3 4 4 4 0 Erv1 / Alr family zinc_ribbon_2 PF13240.1 KFP04396.1 - 0.013 14.9 25.6 0.58 9.7 0.4 5.1 5 0 0 5 5 5 0 zinc-ribbon domain DUF329 PF03884.9 KFP04396.1 - 0.019 14.5 11.4 5.8 6.5 0.1 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF329) Zn_Tnp_IS1595 PF12760.2 KFP04396.1 - 0.022 14.5 23.8 0.023 14.5 1.8 3.8 2 1 1 3 3 2 0 Transposase zinc-ribbon domain BolA PF01722.13 KFP04396.1 - 0.025 14.5 0.8 0.025 14.5 0.6 2.5 2 1 1 3 3 3 0 BolA-like protein LIM PF00412.17 KFP04396.1 - 0.034 14.1 17.1 0.093 12.8 1.7 4.0 1 1 2 4 4 3 0 LIM domain zf-ISL3 PF14690.1 KFP04396.1 - 0.035 14.1 17.9 1.3 9.1 0.1 4.7 4 1 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-CSL PF05207.8 KFP04396.1 - 0.036 13.5 9.8 3.2 7.3 4.2 3.7 2 1 2 4 4 4 0 CSL zinc finger C1_1 PF00130.17 KFP04396.1 - 0.055 13.2 23.5 0.49 10.1 1.4 4.1 1 1 3 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.7 KFP04396.1 - 0.055 13.2 15.2 3.8 7.3 0.3 4.2 2 1 2 4 4 4 0 zinc-ribbons DUF3797 PF12677.2 KFP04396.1 - 0.057 13.0 5.3 5.6 6.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3797) DUF2256 PF10013.4 KFP04396.1 - 0.064 13.0 12.2 39 4.1 0.1 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_5 PF13719.1 KFP04396.1 - 0.066 12.8 18.8 1.2 8.7 0.7 4.5 5 0 0 5 5 4 0 zinc-ribbon domain Sgf11 PF08209.6 KFP04396.1 - 0.079 12.2 7.1 3.2 7.1 0.0 4.3 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) HypA PF01155.14 KFP04396.1 - 0.083 12.5 13.0 6.3 6.5 0.5 3.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family RRN7 PF11781.3 KFP04396.1 - 0.11 12.0 7.9 14 5.3 0.0 4.2 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 C1_3 PF07649.7 KFP04396.1 - 0.13 12.3 11.0 3.8 7.6 0.0 4.5 4 1 1 5 5 4 0 C1-like domain zf-met2 PF12907.2 KFP04396.1 - 0.13 12.2 6.6 15 5.6 0.0 3.9 4 0 0 4 4 4 0 Zinc-binding YhfH PF14149.1 KFP04396.1 - 0.15 11.8 14.1 2.6 7.9 0.3 4.7 5 0 0 5 5 5 0 YhfH-like protein DUF164 PF02591.10 KFP04396.1 - 0.15 11.8 9.3 6.3 6.7 0.1 4.0 4 0 0 4 4 4 0 Putative zinc ribbon domain zf-RING_4 PF14570.1 KFP04396.1 - 0.16 11.6 12.2 1.3 8.6 0.1 3.8 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.9 KFP04396.1 - 0.17 11.5 8.4 21 4.8 0.3 4.3 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS C1_4 PF07975.7 KFP04396.1 - 0.18 11.8 17.7 2 8.5 0.5 4.1 1 1 4 5 5 5 0 TFIIH C1-like domain Baculo_IE-1 PF05290.6 KFP04396.1 - 0.18 11.5 3.9 0.51 10.0 2.7 1.8 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TerY-C PF15616.1 KFP04396.1 - 0.22 11.4 13.6 0.077 12.9 2.0 2.9 1 1 2 3 3 3 0 TerY-C metal binding domain zf-FCS PF06467.9 KFP04396.1 - 0.23 11.1 15.2 0.6 9.7 0.2 4.2 4 1 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif UPF0547 PF10571.4 KFP04396.1 - 0.24 11.1 22.8 6.5 6.5 1.1 5.0 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 TFIIS_C PF01096.13 KFP04396.1 - 0.28 10.8 17.0 13 5.5 0.6 4.9 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.1 KFP04396.1 - 0.33 10.6 18.1 3.5 7.3 0.6 4.5 5 0 0 5 5 4 0 zinc-ribbon domain zf-LYAR PF08790.6 KFP04396.1 - 0.33 10.6 12.2 7.1 6.4 0.3 5.0 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger PRP21_like_P PF12230.3 KFP04396.1 - 0.42 10.0 2.2 1.3 8.5 0.3 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Elf1 PF05129.8 KFP04396.1 - 0.62 9.7 11.7 1.5 8.5 0.1 3.2 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like T4_baseplate PF12322.3 KFP04396.1 - 0.7 9.0 3.9 11 5.2 0.0 3.3 2 1 2 4 4 4 0 T4 bacteriophage base plate protein Rubredoxin PF00301.15 KFP04396.1 - 0.75 9.7 8.8 23 4.9 2.3 3.6 3 1 0 3 3 3 0 Rubredoxin Zn_ribbon_recom PF13408.1 KFP04396.1 - 0.86 9.9 17.1 6.6 7.0 2.9 3.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Nudix_N_2 PF14803.1 KFP04396.1 - 0.94 9.2 11.3 10 5.8 0.1 4.4 5 0 0 5 5 4 0 Nudix N-terminal FYDLN_acid PF09538.5 KFP04396.1 - 1.2 9.7 8.1 33 5.1 0.5 3.8 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) DNA_RNApol_7kD PF03604.8 KFP04396.1 - 1.4 8.4 14.1 36 3.9 0.1 5.1 5 1 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit DUF2688 PF10892.3 KFP04396.1 - 2.3 7.9 7.5 33 4.2 0.1 4.0 5 0 0 5 5 4 0 Protein of unknown function (DUF2688) Rpr2 PF04032.11 KFP04396.1 - 2.5 8.0 11.4 0.57 10.0 0.1 2.8 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-TFIIB PF13453.1 KFP04396.1 - 2.5 7.3 9.6 11 5.2 0.0 3.7 3 1 1 4 4 4 0 Transcription factor zinc-finger PHD PF00628.24 KFP04396.1 - 2.5 7.8 14.2 7.1 6.3 3.4 3.4 3 0 0 3 3 3 0 PHD-finger zf-IS66 PF13005.2 KFP04396.1 - 3.1 7.8 11.9 28 4.7 0.2 4.4 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Mut7-C PF01927.11 KFP04396.1 - 3.4 7.6 16.4 11 5.9 0.6 3.9 2 1 2 4 4 4 0 Mut7-C RNAse domain Ribosomal_L37ae PF01780.14 KFP04396.1 - 3.6 7.5 12.7 13 5.7 0.2 4.0 1 1 3 4 4 4 0 Ribosomal L37ae protein family Yippee-Mis18 PF03226.9 KFP04396.1 - 3.9 7.5 11.5 16 5.6 1.4 3.4 1 1 3 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RING_5 PF14634.1 KFP04396.1 - 4.4 7.1 19.1 18 5.1 0.0 4.0 3 2 0 3 3 3 0 zinc-RING finger domain zf-C4_Topoisom PF01396.14 KFP04396.1 - 4.6 6.8 11.0 7.5 6.1 0.1 3.7 4 0 0 4 4 3 0 Topoisomerase DNA binding C4 zinc finger zf-C2H2_7 PF15269.1 KFP04396.1 - 6.9 6.6 12.9 3.1 7.7 0.3 3.2 2 1 1 3 3 3 0 Zinc-finger DUF3534 PF12053.3 KFP04397.1 - 1.4e-15 57.4 0.1 1.5e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3534) Ank_2 PF12796.2 KFP04398.1 - 2.7e-37 126.9 1.7 4e-21 75.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP04398.1 - 2.6e-34 115.3 6.5 2.9e-09 36.2 0.0 5.8 5 1 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFP04398.1 - 2.4e-28 97.9 4.4 8.2e-10 38.9 0.1 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP04398.1 - 9.9e-26 89.1 4.4 1.5e-10 40.9 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP04398.1 - 1.1e-23 80.8 1.6 0.00012 21.9 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat SOCS_box PF07525.11 KFP04398.1 - 1.2e-12 47.5 2.1 2.2e-12 46.6 1.4 1.4 1 0 0 1 1 1 1 SOCS box DUF1356 PF07092.7 KFP04399.1 - 3.6e-72 242.3 6.3 4e-72 242.2 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.8 KFP04399.1 - 0.0031 17.8 0.3 0.0049 17.2 0.2 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF2393 PF09624.5 KFP04399.1 - 0.06 12.8 0.4 0.06 12.8 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Amnionless PF14828.1 KFP04399.1 - 0.12 10.8 0.1 0.14 10.6 0.1 1.0 1 0 0 1 1 1 0 Amnionless COLFI PF01410.13 KFP04400.1 - 6e-52 176.1 0.0 6.5e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Plasmodium_HRP PF05403.6 KFP04401.1 - 0.48 9.9 16.3 5 6.6 4.9 2.0 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) RVT_1 PF00078.22 KFP04402.1 - 2.4e-18 66.2 0.0 3.9e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.20 KFP04403.1 - 4.7e-09 36.3 0.0 6.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase PRY PF13765.1 KFP04405.1 - 6.6e-20 70.3 0.1 1e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 SPRY-associated domain SPRY PF00622.23 KFP04405.1 - 7.7e-14 51.8 0.0 9.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 SPRY domain zf-H2C2_2 PF13465.1 KFP04406.1 - 2.4e-45 150.6 62.2 8.5e-09 35.2 1.3 9.2 9 0 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04406.1 - 5e-39 130.3 63.5 1.4e-06 28.3 1.5 8.1 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04406.1 - 9.4e-29 97.6 54.6 0.00056 20.0 0.6 8.2 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP04406.1 - 3.1e-25 87.2 44.3 3.6e-05 23.4 1.2 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP04406.1 - 1.3e-11 44.2 20.5 0.053 13.6 0.0 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFP04406.1 - 9.1e-07 28.9 30.1 0.032 14.3 1.5 5.5 3 3 2 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 KFP04406.1 - 0.0001 22.0 30.6 5.2 6.9 4.9 5.0 1 1 1 2 2 2 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 KFP04406.1 - 0.0003 20.6 40.0 0.76 9.7 2.6 7.6 3 2 3 6 6 6 2 Zinc ribbon domain C1_1 PF00130.17 KFP04406.1 - 0.00052 19.6 19.3 2.9 7.7 1.3 5.5 1 1 2 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TerY-C PF15616.1 KFP04406.1 - 0.0061 16.4 0.1 0.0061 16.4 0.1 4.3 2 1 2 4 4 4 1 TerY-C metal binding domain zf-BED PF02892.10 KFP04406.1 - 0.0078 15.9 1.7 0.0078 15.9 1.2 7.5 3 1 4 8 8 8 1 BED zinc finger Ogr_Delta PF04606.7 KFP04406.1 - 0.0089 15.6 0.5 0.0089 15.6 0.3 5.9 4 1 1 6 6 6 1 Ogr/Delta-like zinc finger XPA_N PF01286.13 KFP04406.1 - 0.015 14.9 27.2 0.37 10.5 0.1 7.5 8 0 0 8 8 8 0 XPA protein N-terminal C1_4 PF07975.7 KFP04406.1 - 0.02 14.8 23.3 0.12 12.4 0.4 5.3 2 2 4 6 6 6 0 TFIIH C1-like domain Trm112p PF03966.11 KFP04406.1 - 0.034 14.5 0.2 0.034 14.5 0.1 3.4 4 1 0 4 4 3 0 Trm112p-like protein zf-C2HC_2 PF13913.1 KFP04406.1 - 0.041 13.5 53.1 0.52 10.0 1.2 8.9 8 1 0 8 8 8 0 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.1 KFP04406.1 - 0.048 13.1 0.9 0.048 13.1 0.6 6.9 4 4 2 6 6 6 0 zinc-ribbon domain LIM PF00412.17 KFP04406.1 - 0.15 12.1 23.8 0.48 10.5 0.1 5.4 3 3 1 4 4 4 0 LIM domain zf-RING_3 PF14369.1 KFP04406.1 - 0.23 11.5 0.1 0.23 11.5 0.1 7.1 8 0 0 8 8 7 0 zinc-finger zf-met PF12874.2 KFP04406.1 - 0.32 11.2 39.9 0.63 10.3 0.2 7.9 8 0 0 8 8 8 0 Zinc-finger of C2H2 type DUF164 PF02591.10 KFP04406.1 - 0.51 10.2 0.1 0.51 10.2 0.1 6.1 6 1 1 7 7 7 0 Putative zinc ribbon domain zf-C2H2_2 PF12756.2 KFP04406.1 - 0.79 9.8 28.3 8.5 6.5 0.0 7.3 2 2 6 8 8 8 0 C2H2 type zinc-finger (2 copies) Rep_fac-A_C PF08646.5 KFP04406.1 - 1 9.0 7.8 3.9 7.1 0.0 4.0 1 1 2 3 3 2 0 Replication factor-A C terminal domain GAGA PF09237.6 KFP04406.1 - 3.1 7.4 26.8 1 9.0 0.7 5.4 3 2 3 6 6 6 0 GAGA factor HypA PF01155.14 KFP04406.1 - 3.5 7.3 24.9 2.3 7.9 1.3 4.4 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family Mut7-C PF01927.11 KFP04406.1 - 4.2 7.3 20.8 1.1 9.2 1.1 5.3 2 2 2 4 4 4 0 Mut7-C RNAse domain FYDLN_acid PF09538.5 KFP04406.1 - 8.3 7.0 22.5 4.9 7.7 0.0 6.7 3 2 3 6 6 6 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.2 KFP04406.1 - 9.3 6.1 44.1 0.18 11.6 2.5 6.1 4 2 2 6 6 6 0 Transposase zinc-ribbon domain Membr_traf_MHD PF10540.4 KFP04407.1 - 9.4e-58 193.8 2.6 9.4e-58 193.8 1.8 2.1 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KFP04407.1 - 5.3e-43 144.7 7.9 1.6e-24 85.5 0.3 4.0 4 0 0 4 4 4 3 C2 domain DUF1041 PF06292.12 KFP04407.1 - 4.2e-41 139.3 0.1 4.2e-41 139.3 0.1 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1041) C1_1 PF00130.17 KFP04407.1 - 8.8e-11 41.3 6.2 2.6e-10 39.8 4.3 1.9 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CTF_NFI PF00859.13 KFP04408.1 - 2.1e-131 438.1 28.3 2.7e-131 437.7 19.6 1.1 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N PF10524.4 KFP04408.1 - 3.9e-26 90.3 4.0 6.4e-26 89.6 2.8 1.4 1 0 0 1 1 1 1 Nuclear factor I protein pre-N-terminus MH1 PF03165.11 KFP04408.1 - 3.5e-12 46.2 0.5 6.5e-12 45.3 0.3 1.5 1 0 0 1 1 1 1 MH1 domain HEAT_2 PF13646.1 KFP04409.1 - 2.5e-16 59.7 0.0 6.3e-15 55.2 0.0 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 KFP04409.1 - 9e-15 53.5 0.7 5.1e-06 26.4 0.0 3.3 3 0 0 3 3 3 3 PBS lyase HEAT-like repeat HEAT PF02985.17 KFP04409.1 - 0.00024 20.9 0.4 0.0095 15.9 0.0 3.1 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KFP04409.1 - 0.021 15.3 0.1 0.17 12.4 0.0 2.4 1 1 1 2 2 2 0 HEAT-like repeat Arm PF00514.18 KFP04409.1 - 0.025 14.4 0.0 0.075 12.8 0.0 1.9 1 1 0 1 1 1 0 Armadillo/beta-catenin-like repeat DDE_Tnp_4 PF13359.1 KFP04410.1 - 1.4e-29 102.7 0.0 2e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 KFP04410.1 - 6.3e-13 48.5 0.0 8.7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.1 KFP04410.1 - 1.5e-06 27.6 0.0 3.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Gemini_AL3 PF01407.12 KFP04410.1 - 0.044 13.2 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Geminivirus AL3 protein WD40 PF00400.27 KFP04411.1 - 9.4e-19 66.5 4.7 6.6e-06 25.8 0.0 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 KFP04411.1 - 1.6e-05 24.6 0.0 0.0085 15.8 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A MFS_2 PF13347.1 KFP04412.1 - 9.4e-20 70.4 12.9 9.4e-20 70.4 8.9 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein DUF3963 PF13124.1 KFP04412.1 - 0.22 11.3 3.9 0.2 11.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) HMG_box PF00505.14 KFP04413.1 - 4.9e-20 71.5 1.0 1.6e-19 69.8 0.7 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP04413.1 - 1e-12 48.2 1.6 1.5e-12 47.6 0.2 2.1 2 0 0 2 2 2 1 HMG-box domain DUF3584 PF12128.3 KFP04413.1 - 0.27 8.5 14.2 0.022 12.0 4.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 KFP04413.1 - 0.31 10.6 17.0 0.13 11.8 4.2 2.2 2 0 0 2 2 2 0 IncA protein Caudo_TAP PF02413.12 KFP04413.1 - 1.5 8.9 7.2 0.45 10.6 0.7 2.3 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein UPF0242 PF06785.6 KFP04413.1 - 2.4 6.7 13.7 0.62 8.6 4.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) APG6 PF04111.7 KFP04413.1 - 4.5 6.2 19.6 3.9 6.4 6.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 KFP04413.1 - 4.9 5.4 11.1 0.35 9.2 1.5 2.0 2 0 0 2 2 2 0 AAA domain DUF4298 PF14131.1 KFP04413.1 - 9.9 6.1 10.3 2 8.3 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) PDZ PF00595.19 KFP04414.1 - 1.4e-07 31.5 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) CBM_X PF06204.6 KFP04414.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative carbohydrate binding domain PIP5K PF01504.13 KFP04415.1 - 2.4e-78 262.7 0.0 3.1e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Toxin_33 PF08121.6 KFP04415.1 - 0.16 11.5 0.8 0.32 10.6 0.5 1.5 1 0 0 1 1 1 0 Waglerin family PID PF00640.18 KFP04416.1 - 2.3e-42 144.3 0.1 3.8e-42 143.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.19 KFP04416.1 - 1.3e-32 111.7 1.5 5.7e-16 58.4 0.1 2.5 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP04416.1 - 7.6e-07 28.9 0.0 0.00022 21.0 0.0 2.4 2 0 0 2 2 2 2 PDZ domain DUF993 PF06187.6 KFP04416.1 - 0.0025 16.4 0.1 0.0037 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF993) Ribosomal_L37 PF08561.5 KFP04417.1 - 1.7e-21 75.5 0.0 2.3e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Homeobox PF00046.24 KFP04418.1 - 1.4e-24 85.4 4.6 2.3e-24 84.7 3.2 1.3 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFP04418.1 - 2e-11 42.9 0.5 4.4e-11 41.9 0.3 1.6 1 0 0 1 1 1 1 OAR domain Pkinase_Tyr PF07714.12 KFP04419.1 - 1e-88 296.8 0.0 1.3e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP04419.1 - 1.2e-46 159.0 0.0 2.3e-46 158.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.19 KFP04419.1 - 3.3e-20 71.6 0.0 7e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFP04419.1 - 4.5e-10 38.7 0.0 8.6e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP04419.1 - 2.2e-07 30.3 0.0 5.9e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP04419.1 - 3.4e-06 26.4 0.1 6.9e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 KFP04419.1 - 0.00069 19.4 0.0 0.0033 17.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFP04419.1 - 0.0062 15.8 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFP04419.1 - 0.028 13.3 0.0 0.084 11.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like SH3_3 PF08239.6 KFP04419.1 - 0.069 13.3 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain RRM_1 PF00076.17 KFP04420.1 - 4.2e-62 205.7 0.1 2.5e-19 68.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP04420.1 - 5.9e-42 141.5 0.1 2.2e-12 46.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP04420.1 - 1.5e-30 104.7 0.2 7.7e-11 41.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP04420.1 - 0.00095 18.9 0.0 0.1 12.4 0.0 2.5 1 1 1 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFP04420.1 - 0.0095 15.6 0.0 0.41 10.4 0.0 2.8 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif E2 PF08199.6 KFP04420.1 - 0.043 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage E2-like protein SDF PF00375.13 KFP04421.1 - 9.7e-128 426.2 27.7 1.1e-127 426.0 19.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family hSH3 PF14603.1 KFP04422.1 - 1.2e-14 54.0 0.0 1.5e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.12 KFP04422.1 - 0.00021 20.6 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFP04422.1 - 0.0029 17.1 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP04422.1 - 0.064 12.6 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Myosin_head PF00063.16 KFP04423.1 - 8.3e-231 767.7 0.0 9.6e-231 767.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFP04423.1 - 7.2e-16 56.2 26.7 0.00031 20.1 0.6 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.1 KFP04423.1 - 0.0068 16.5 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP04423.1 - 0.025 14.5 3.5 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KFP04423.1 - 0.08 12.0 0.1 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin MBD_C PF14048.1 KFP04424.1 - 6.9e-37 125.9 0.4 1.2e-36 125.1 0.0 1.6 2 0 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 MBD PF01429.14 KFP04424.1 - 1.6e-09 37.1 0.2 1.7e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Methyl-CpG binding domain DUF1107 PF06526.7 KFP04424.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1107) TLV_coat PF00429.14 KFP04425.1 - 3.8e-111 372.2 0.4 4.3e-111 372.1 0.3 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) EI24 PF07264.6 KFP04425.1 - 0.041 13.2 0.2 0.068 12.5 0.1 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) SlyX PF04102.7 KFP04425.1 - 0.065 13.6 0.2 0.065 13.6 0.1 2.3 2 1 1 3 3 3 0 SlyX UCR_6-4kD PF08997.5 KFP04426.1 - 3.9e-26 90.5 1.3 4.2e-26 90.4 0.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.4 KFP04426.1 - 0.00022 20.8 1.5 0.0011 18.6 1.0 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HLH PF00010.21 KFP04427.1 - 3.1e-10 39.6 1.0 7.5e-10 38.3 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4349 PF14257.1 KFP04427.1 - 0.064 12.4 0.7 0.11 11.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Homeobox PF00046.24 KFP04428.1 - 1.9e-11 43.3 1.2 2.8e-11 42.8 0.9 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP04428.1 - 6.1e-05 22.6 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain PH_3 PF14593.1 KFP04428.1 - 0.093 12.6 0.8 0.12 12.3 0.5 1.1 1 0 0 1 1 1 0 PH domain HAD PF12710.2 KFP04429.1 - 2e-14 54.2 0.1 6.2e-14 52.6 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFP04429.1 - 5.1e-14 53.2 0.1 1.4e-07 32.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP04429.1 - 3e-13 49.5 0.0 1.4e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KFP04429.1 - 1.7e-12 46.8 0.0 5.6e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.7 KFP04429.1 - 0.00012 21.8 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_5 PF12695.2 KFP04430.1 - 2e-29 102.2 0.0 2.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP04430.1 - 2.3e-14 53.8 0.0 7.3e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP04430.1 - 1.1e-07 31.6 0.0 0.003 17.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFP04430.1 - 6e-07 28.8 0.0 3.5e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KFP04430.1 - 5e-05 22.6 0.0 8.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.7 KFP04430.1 - 0.0011 17.7 0.1 0.0017 17.1 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) UPF0227 PF05728.7 KFP04430.1 - 0.0016 18.2 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 KFP04430.1 - 0.0055 16.1 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KFP04430.1 - 0.0069 15.8 0.0 0.035 13.5 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase zf-A20 PF01754.11 KFP04431.1 - 7.1e-13 47.8 6.1 7.1e-13 47.8 4.2 2.1 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.11 KFP04431.1 - 4.8e-12 45.5 5.7 4.8e-12 45.5 3.9 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger zf-RING_5 PF14634.1 KFP04431.1 - 3.4 7.4 9.1 24 4.7 0.1 2.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C4 PF00105.13 KFP04432.1 - 1.9e-33 114.4 13.6 3.9e-33 113.4 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) SCAMP PF04144.8 KFP04433.1 - 8.6e-72 240.7 18.5 9.8e-72 240.5 12.8 1.0 1 0 0 1 1 1 1 SCAMP family Pkinase PF00069.20 KFP04434.1 - 2.9e-34 118.4 0.0 3.7e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CK1gamma_C PF12605.3 KFP04434.1 - 1.3e-20 73.7 4.4 2.3e-20 72.9 3.1 1.4 1 0 0 1 1 1 1 Casein kinase 1 gamma C terminal Pkinase_Tyr PF07714.12 KFP04434.1 - 2.7e-14 52.8 0.0 3.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.3 KFP04434.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 PHR PF08005.7 KFP04435.1 - 3.6e-52 176.5 0.6 5.4e-52 175.9 0.4 1.3 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 KFP04435.1 - 8.5e-22 77.2 0.3 6.6e-20 71.1 0.0 2.9 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.10 KFP04435.1 - 6.4e-10 38.8 0.7 2e-08 33.9 0.1 3.0 1 1 1 2 2 2 1 BTB And C-terminal Kelch Pkinase PF00069.20 KFP04436.1 - 2.7e-49 167.6 0.0 9.9e-49 165.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04436.1 - 1.2e-16 60.5 0.0 8.1e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KFP04436.1 - 1.7e-05 23.9 0.1 3.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP04436.1 - 0.055 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFP04436.1 - 0.081 12.6 0.2 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP04436.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Mob1_phocein PF03637.12 KFP04437.1 - 1.1e-77 259.6 0.5 1.2e-77 259.5 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family DOT1 PF08123.8 KFP04438.1 - 4.1e-83 277.7 0.4 1.2e-82 276.2 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 zf-met PF12874.2 KFP04439.1 - 1.2e-06 28.4 2.1 1.2e-06 28.4 1.4 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 KFP04439.1 - 0.01 15.4 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 KFP04439.1 - 0.049 12.8 2.5 0.087 12.1 1.7 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like AMH_N PF04709.7 KFP04441.1 - 2.9e-66 223.9 2.9 1.9e-46 158.7 0.7 2.1 1 1 1 2 2 2 2 Anti-Mullerian hormone, N terminal region TGF_beta PF00019.15 KFP04441.1 - 5.7e-20 71.5 0.2 9e-20 70.9 0.2 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain MRP-L20 PF12824.2 KFP04441.1 - 0.28 11.1 2.3 0.58 10.1 1.6 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 JSRP PF15312.1 KFP04442.1 - 3.4e-19 68.5 1.6 3.4e-19 68.5 1.1 2.0 2 0 0 2 2 2 1 Junctional sarcoplasmic reticulum protein Pkinase PF00069.20 KFP04443.1 - 0.0019 17.3 0.0 0.051 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04443.1 - 0.081 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase LRR_8 PF13855.1 KFP04444.1 - 2.9e-41 139.0 37.8 6.8e-13 48.1 2.5 5.8 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 KFP04444.1 - 2.4e-22 78.1 32.7 2.8e-07 29.9 0.2 6.6 3 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP04444.1 - 3.3e-18 65.6 0.1 2e-11 43.7 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) I-set PF07679.11 KFP04444.1 - 3.8e-17 61.9 0.0 6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFP04444.1 - 1e-12 46.1 33.8 0.02 14.8 0.0 10.8 12 0 0 12 12 11 3 Leucine Rich Repeat Ig_2 PF13895.1 KFP04444.1 - 1e-08 35.1 0.0 2.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP04444.1 - 3.4e-08 33.8 0.0 2.5e-07 31.1 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP04444.1 - 1.9e-07 30.9 0.0 1.4e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin V-set domain LRR_6 PF13516.1 KFP04444.1 - 3.6e-07 29.5 21.7 2.1 8.6 0.0 8.9 7 1 1 8 8 8 1 Leucine Rich repeat ig PF00047.20 KFP04444.1 - 4.3e-07 29.9 0.0 1.2e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRRNT PF01462.13 KFP04444.1 - 6.2e-05 22.3 3.8 6.2e-05 22.3 2.7 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRRCT PF01463.19 KFP04444.1 - 0.015 15.4 6.0 0.63 10.5 0.0 4.2 4 0 0 4 4 4 0 Leucine rich repeat C-terminal domain LRR_7 PF13504.1 KFP04444.1 - 0.074 13.2 30.9 7.6 7.2 0.1 9.7 11 0 0 11 11 10 0 Leucine rich repeat C2-set_2 PF08205.7 KFP04444.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain CUB PF00431.15 KFP04446.1 - 4e-13 49.3 0.0 4.5e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 CUB domain TFIID_20kDa PF03847.8 KFP04447.1 - 2.9e-36 123.5 2.8 4e-36 123.1 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KFP04447.1 - 6.7e-06 26.0 0.2 1e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFP04447.1 - 2e-05 24.5 0.1 3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 KFP04447.1 - 0.00084 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF4 PF05236.9 KFP04447.1 - 0.0053 16.0 0.1 0.0061 15.8 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Condensin2nSMC PF12422.3 KFP04447.1 - 0.014 15.1 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Ras PF00071.17 KFP04448.1 - 3.7e-26 91.4 0.0 4.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Sec1 PF00995.18 KFP04448.1 - 0.096 11.3 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 Sec1 family Miro PF08477.8 KFP04448.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 KFP04448.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family RRM_1 PF00076.17 KFP04449.1 - 7.3e-13 47.9 0.0 1.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP04449.1 - 2.4e-05 24.2 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Epimerase PF01370.16 KFP04450.1 - 3.7e-52 177.1 0.0 4.5e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KFP04450.1 - 3.9e-19 68.3 0.5 1e-18 66.9 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KFP04450.1 - 3.5e-18 65.3 0.0 1e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFP04450.1 - 1.2e-13 50.6 0.0 4.8e-13 48.6 0.0 1.8 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KFP04450.1 - 5e-12 45.3 0.0 3e-11 42.7 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KFP04450.1 - 7.7e-11 42.3 0.0 2.5e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFP04450.1 - 1.5e-10 41.2 0.0 2.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFP04450.1 - 4.3e-10 38.9 0.0 2.1e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KFP04450.1 - 5.7e-06 25.7 0.6 0.013 14.7 0.1 2.4 2 1 0 2 2 2 2 NmrA-like family KR PF08659.5 KFP04450.1 - 1.9e-05 24.3 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KFP04450.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Abhydrolase_2 PF02230.11 KFP04451.1 - 9.3e-85 283.4 0.0 1e-84 283.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFP04451.1 - 9.8e-12 45.2 0.0 2.1e-09 37.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP04451.1 - 1.7e-10 40.8 0.1 4.3e-10 39.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFP04451.1 - 1.2e-07 31.5 0.0 2e-06 27.5 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFP04451.1 - 0.00029 20.1 0.1 0.068 12.3 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 KFP04451.1 - 0.00039 19.9 0.0 0.0055 16.1 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 KFP04451.1 - 0.00066 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.17 KFP04451.1 - 0.0019 17.9 0.0 0.0068 16.1 0.0 1.8 1 1 1 2 2 2 1 Cutinase DUF2974 PF11187.3 KFP04451.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 KFP04451.1 - 0.028 13.9 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFP04451.1 - 0.056 13.0 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 KFP04451.1 - 0.18 10.2 0.0 0.34 9.3 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PITH PF06201.8 KFP04452.1 - 1.5e-34 118.9 0.0 1.8e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Elongin_A PF06881.6 KFP04453.1 - 2.9e-30 104.8 0.4 2.9e-30 104.8 0.3 3.3 4 1 1 5 5 5 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Med26 PF08711.6 KFP04453.1 - 1.7e-15 56.2 0.3 3e-15 55.4 0.2 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_L5_C PF00673.16 KFP04454.1 - 2.1e-23 81.8 0.0 3e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFP04454.1 - 7.8e-21 73.6 0.1 2.5e-19 68.8 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L5 Palm_thioest PF02089.10 KFP04455.1 - 3e-155 515.2 0.0 3.4e-155 515.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 KFP04455.1 - 0.00018 21.1 0.0 0.00096 18.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold CAP_N PF01213.14 KFP04456.1 - 7.8e-110 367.0 0.7 2.7e-89 299.5 0.1 2.1 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KFP04456.1 - 7.9e-69 230.0 4.2 1.1e-68 229.5 2.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KFP04456.1 - 6.9e-06 25.4 2.1 1.4e-05 24.4 1.5 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor C RE_Bsp6I PF09504.5 KFP04456.1 - 0.041 13.3 0.2 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 Bsp6I restriction endonuclease DUF3114 PF11311.3 KFP04456.1 - 0.041 13.2 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) WH2 PF02205.15 KFP04456.1 - 0.046 13.3 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 WH2 motif MFS_2 PF13347.1 KFP04457.1 - 3.2e-79 266.3 21.5 3.6e-46 157.4 7.0 2.0 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.11 KFP04457.1 - 3e-09 36.0 18.0 1.4e-07 30.5 11.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_N PF01056.13 KFP04458.1 - 1.4e-35 123.0 3.2 6.6e-25 87.9 0.0 2.6 1 1 1 2 2 2 2 Myc amino-terminal region HLH PF00010.21 KFP04458.1 - 3.2e-13 49.1 0.3 1.3e-12 47.1 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HpaP PF09483.5 KFP04458.1 - 0.0034 17.3 7.7 0.0063 16.4 5.3 1.4 1 0 0 1 1 1 1 Type III secretion protein (HpaP) DUF1180 PF06679.7 KFP04458.1 - 1.2 9.0 7.9 0.41 10.5 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) IPPT PF01715.12 KFP04459.1 - 7.8e-57 192.1 0.2 1.1e-56 191.7 0.1 1.1 1 0 0 1 1 1 1 IPP transferase MscS_porin PF12795.2 KFP04459.1 - 0.96 8.7 5.1 0.58 9.4 1.8 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Mst1_SARAH PF11629.3 KFP04459.1 - 2 8.2 7.9 1.9 8.3 0.0 3.2 3 1 0 3 3 3 0 C terminal SARAH domain of Mst1 DUF1394 PF07159.7 KFP04460.1 - 1.8e-106 355.6 1.1 3.8e-106 354.6 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) EF-hand_1 PF00036.27 KFP04461.1 - 6.3e-24 81.4 14.9 2.3e-08 32.7 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KFP04461.1 - 1e-21 74.8 5.6 5.2e-07 29.0 0.1 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KFP04461.1 - 1.9e-20 72.7 6.4 1.9e-12 47.1 0.5 3.2 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP04461.1 - 3.6e-16 57.6 15.0 1.1e-06 27.6 0.3 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFP04461.1 - 6.6e-15 54.4 9.7 2.3e-07 30.3 0.5 4.4 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP04461.1 - 6.9e-05 22.8 2.6 0.045 13.7 1.8 3.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFP04461.1 - 0.0038 16.9 7.1 4.1 7.1 0.4 3.7 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand Homez PF11569.3 KFP04461.1 - 0.066 12.2 0.1 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Caleosin PF05042.8 KFP04461.1 - 0.25 10.8 1.6 3.8 7.0 1.1 2.6 1 1 0 1 1 1 0 Caleosin related protein EF-hand_10 PF14788.1 KFP04461.1 - 1.2 8.8 6.3 15 5.3 0.2 3.2 4 0 0 4 4 4 0 EF hand 5-nucleotidase PF06189.7 KFP04462.1 - 1.1e-114 381.6 0.0 1.7e-113 377.7 0.0 1.9 1 1 1 2 2 2 2 5'-nucleotidase Pro_isomerase PF00160.16 KFP04463.1 - 6.2e-16 58.9 0.1 9.2e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KFP04463.1 - 2.2e-09 36.7 0.1 4.7e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP04463.1 - 6.5e-09 35.5 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP04463.1 - 2.4e-07 30.6 0.1 4.1e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TGF_beta PF00019.15 KFP04464.1 - 1.9e-41 140.5 3.7 3e-41 139.9 2.6 1.3 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP04464.1 - 4.6e-34 117.7 0.0 6.6e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide WD40 PF00400.27 KFP04465.1 - 2.3e-65 214.2 4.7 6.1e-11 41.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFP04465.1 - 8.2e-09 35.4 0.3 0.0061 16.2 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFP04465.1 - 0.00029 19.2 0.1 0.45 8.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 KFP04465.1 - 0.0077 14.4 6.4 1.4 6.9 0.0 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 KFP04465.1 - 0.066 12.8 0.0 0.53 10.0 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat zf-CCHC_3 PF13917.1 KFP04466.1 - 0.00023 20.8 1.4 0.00023 20.8 1.0 1.9 2 0 0 2 2 2 1 Zinc knuckle CpXC PF14353.1 KFP04466.1 - 0.042 13.8 1.1 0.068 13.1 0.7 1.3 1 0 0 1 1 1 0 CpXC protein Rtf2 PF04641.7 KFP04466.1 - 0.049 12.8 18.7 0.061 12.5 13.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Herpes_gE PF02480.11 KFP04466.1 - 0.05 11.8 5.9 0.17 10.0 4.1 1.8 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_UL55 PF04537.7 KFP04466.1 - 0.057 12.8 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein SR-25 PF10500.4 KFP04466.1 - 0.084 12.3 34.4 0.13 11.7 23.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3827 PF12877.2 KFP04466.1 - 1.3 7.0 12.3 1.4 6.9 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TFIIF_alpha PF05793.7 KFP04466.1 - 1.6 6.9 26.6 2.3 6.5 18.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 KFP04466.1 - 1.8 6.5 17.0 2.1 6.2 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 KFP04466.1 - 2 7.8 17.6 2.6 7.5 12.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Vfa1 PF08432.5 KFP04466.1 - 2.8 7.9 22.2 5.5 6.9 15.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CMV_1a PF12467.3 KFP04466.1 - 4.9 7.4 11.8 8.8 6.6 8.2 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Vpu PF00558.14 KFP04466.1 - 5.3 6.6 5.4 13 5.4 3.8 1.6 1 0 0 1 1 1 0 Vpu protein Zip PF02535.17 KFP04466.1 - 7.9 5.3 5.4 7.7 5.4 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Lipocalin PF00061.18 KFP04467.1 - 1.5e-30 106.0 1.9 1.7e-30 105.9 1.3 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFP04467.1 - 4.8e-09 36.0 0.8 5.6e-09 35.7 0.6 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Serinc PF03348.10 KFP04468.1 - 2.2e-164 547.2 17.2 2.5e-164 547.0 11.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3923 PF13061.1 KFP04468.1 - 0.06 13.2 0.2 0.06 13.2 0.1 5.0 7 0 0 7 7 7 0 Protein of unknown function (DUF3923) Pox_A14 PF05767.7 KFP04468.1 - 0.97 9.4 8.2 0.98 9.4 2.3 3.1 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Abhydrolase_6 PF12697.2 KFP04469.1 - 0.08 12.8 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Endothelin PF00322.12 KFP04470.1 - 1.5e-19 68.9 14.4 1e-18 66.2 3.2 2.3 2 0 0 2 2 2 2 Endothelin family PXA PF02194.10 KFP04471.1 - 5.8e-32 110.7 0.0 1.9e-31 109.0 0.0 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KFP04471.1 - 2.9e-24 85.3 0.8 4.5e-23 81.4 0.2 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KFP04471.1 - 1e-19 70.4 0.1 2.3e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 PX domain DUF2448 PF10476.4 KFP04471.1 - 0.0096 15.4 0.1 0.063 12.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2448) ADAM_spacer1 PF05986.9 KFP04472.1 - 8.2e-34 115.8 0.0 1.2e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFP04472.1 - 7.5e-21 74.6 0.0 7.5e-21 74.6 0.0 1.7 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 KFP04472.1 - 3.7e-17 62.1 36.6 1.7e-07 31.2 2.2 6.0 5 0 0 5 5 5 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 KFP04472.1 - 1.2e-12 48.1 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFP04472.1 - 6.9e-09 36.2 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP04472.1 - 6.8e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP04472.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.9 KFP04473.1 - 5.4e-32 110.0 0.0 8e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFP04473.1 - 1.1e-23 83.8 0.0 1.7e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 KFP04473.1 - 7.1e-16 58.0 57.9 7.2e-09 35.6 6.3 6.1 6 0 0 6 6 6 3 Thrombospondin type 1 domain Reprolysin_5 PF13688.1 KFP04473.1 - 2.1e-14 53.9 0.0 2.1e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFP04473.1 - 1.3e-12 48.3 0.3 2.2e-12 47.5 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP04473.1 - 3e-10 39.9 0.0 5.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP04473.1 - 1.6e-07 31.5 0.0 2.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFP04473.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin BTB PF00651.26 KFP04474.1 - 1.9e-29 101.8 0.7 3.3e-29 101.0 0.5 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFP04474.1 - 4.1e-18 64.5 24.1 0.00016 21.8 0.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04474.1 - 2.3e-16 58.8 19.3 0.00021 21.3 0.6 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP04474.1 - 6.5e-14 51.4 22.8 2.5e-06 27.4 0.2 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFP04474.1 - 8.7e-11 41.3 14.6 0.0045 16.8 0.1 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KFP04474.1 - 4e-10 39.5 19.9 0.023 14.8 0.2 5.6 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP04474.1 - 4.1e-09 36.3 10.1 0.043 13.9 0.0 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP04474.1 - 9.5e-05 22.4 13.0 0.31 11.1 1.8 4.1 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Glyco_transf_10 PF00852.14 KFP04474.1 - 0.0024 16.4 0.8 0.03 12.9 0.2 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) DUF3342 PF11822.3 KFP04474.1 - 0.17 10.9 6.7 0.39 9.8 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3342) Zn_Tnp_IS1595 PF12760.2 KFP04474.1 - 0.18 11.6 19.8 0.074 12.8 2.6 3.4 1 1 2 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFP04474.1 - 0.42 10.6 17.0 0.54 10.2 2.0 4.5 3 1 1 4 4 4 0 Zinc ribbon domain DUF678 PF05077.7 KFP04474.1 - 0.59 10.1 6.2 0.33 10.9 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF678) zf-TFIIB PF13453.1 KFP04474.1 - 0.88 8.8 8.5 0.22 10.7 0.7 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger CpXC PF14353.1 KFP04474.1 - 2.7 7.9 9.7 68 3.4 0.3 3.7 1 1 1 2 2 2 0 CpXC protein LIM PF00412.17 KFP04474.1 - 3.2 7.8 12.5 0.56 10.3 3.8 3.2 3 1 0 3 3 3 0 LIM domain C1_1 PF00130.17 KFP04474.1 - 4.7 7.0 10.0 0.94 9.2 2.4 2.9 2 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_4 PF13717.1 KFP04474.1 - 6.3 6.5 12.8 16 5.2 0.1 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-BED PF02892.10 KFP04474.1 - 7.6 6.3 16.7 9.1 6.1 1.1 4.4 2 1 2 4 4 4 0 BED zinc finger dUTPase PF00692.14 KFP04475.1 - 1.5e-15 56.8 0.0 1.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 dUTPase DUF348 PF03990.9 KFP04475.1 - 0.18 11.4 1.9 0.22 11.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF348) 7tm_4 PF13853.1 KFP04476.1 - 6e-22 77.9 1.0 6e-22 77.9 0.7 2.1 3 0 0 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFP04476.1 - 2.6e-20 72.6 11.9 5.6e-20 71.5 1.9 2.2 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04476.1 - 0.00045 19.4 4.4 0.002 17.3 1.8 2.0 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx FEZ PF07763.8 KFP04477.1 - 1.6e-57 195.0 2.4 3.7e-57 193.8 1.7 1.6 1 1 0 1 1 1 1 FEZ-like protein BUD22 PF09073.5 KFP04477.1 - 0.067 12.2 4.3 0.1 11.6 3.0 1.2 1 0 0 1 1 1 0 BUD22 DUF2376 PF09550.5 KFP04477.1 - 1.3 9.2 6.1 5.7 7.1 2.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical phage protein (DUF2376) Homeobox_KN PF05920.6 KFP04478.1 - 2.2e-19 68.8 1.6 4.6e-19 67.8 1.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFP04478.1 - 3.8e-08 32.8 0.5 9.1e-08 31.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain Med4 PF10018.4 KFP04478.1 - 0.019 14.3 9.3 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Myc_N PF01056.13 KFP04478.1 - 0.078 12.1 5.7 0.22 10.6 4.0 1.8 1 0 0 1 1 1 0 Myc amino-terminal region Prothymosin PF03247.9 KFP04478.1 - 0.19 11.9 20.1 0.38 10.9 14.0 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family TFIIA PF03153.8 KFP04478.1 - 0.35 10.6 12.0 0.16 11.8 3.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 KFP04478.1 - 0.41 9.0 9.5 0.63 8.4 6.6 1.2 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 KFP04478.1 - 0.41 9.8 13.1 0.67 9.1 9.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.11 KFP04478.1 - 0.69 8.8 8.5 1.2 8.0 5.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 KFP04478.1 - 1.6 7.9 4.4 0.29 10.3 0.6 1.5 2 0 0 2 2 2 0 NOA36 protein TT_ORF2 PF02957.10 KFP04478.1 - 1.8 9.2 12.2 3 8.5 3.4 2.6 2 0 0 2 2 2 0 TT viral ORF2 Nop14 PF04147.7 KFP04478.1 - 3.3 5.5 10.5 4.6 5.0 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 KFP04478.1 - 3.7 7.4 15.7 0.052 13.4 5.4 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoplasmin PF03066.10 KFP04478.1 - 4.7 6.7 18.3 9 5.7 12.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Gemini_mov PF01708.11 KFP04479.1 - 0.01 15.3 0.5 0.017 14.6 0.0 1.6 1 1 0 1 1 1 0 Geminivirus putative movement protein MFS_1 PF07690.11 KFP04480.1 - 2.4e-44 151.5 45.0 1.7e-34 119.1 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KFP04480.1 - 0.00022 19.4 1.0 0.13 10.2 0.2 3.0 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family I-set PF07679.11 KFP04481.1 - 2.8e-14 52.7 0.0 8.7e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFP04481.1 - 4.4e-13 49.1 0.0 2.4e-08 33.8 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP04481.1 - 1.8e-11 44.3 0.0 8.5e-10 38.9 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.1 KFP04481.1 - 1.4e-09 37.8 0.0 3.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFP04481.1 - 6.6e-07 29.3 0.0 3e-05 24.0 0.0 2.6 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 KFP04481.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFP04482.1 - 6.1e-15 54.8 0.1 2e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP04482.1 - 9e-13 48.1 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain fn3 PF00041.16 KFP04482.1 - 3.8e-11 42.9 0.4 0.0002 21.3 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Ig_3 PF13927.1 KFP04482.1 - 5.5e-07 30.0 0.0 8.6e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP04482.1 - 3.6e-06 26.8 0.3 7e-05 22.6 0.0 2.8 3 1 0 3 3 3 1 Immunoglobulin V-set domain ig PF00047.20 KFP04482.1 - 7.6e-06 25.9 0.0 3.8e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain C2-set_2 PF08205.7 KFP04482.1 - 0.00013 21.7 0.0 0.00035 20.4 0.0 1.7 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP04482.1 - 0.041 12.1 0.0 0.049 11.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.3 KFP04482.1 - 0.059 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 I-set PF07679.11 KFP04483.1 - 6.5e-13 48.3 0.0 1.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain fn3 PF00041.16 KFP04483.1 - 5e-11 42.5 0.1 0.00032 20.7 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.1 KFP04483.1 - 1.6e-08 34.5 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP04483.1 - 6.5e-07 29.7 0.0 7.9e-05 23.0 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain C2-set_2 PF08205.7 KFP04483.1 - 0.00016 21.4 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain ig PF00047.20 KFP04483.1 - 0.00042 20.3 0.0 0.00084 19.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP04483.1 - 0.0018 18.1 0.0 0.038 13.8 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP04485.1 - 3.2e-13 49.5 0.1 1.9e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP04485.1 - 8.7e-12 44.7 0.0 1.2e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFP04485.1 - 1.8e-09 37.5 0.0 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP04485.1 - 3.8e-09 36.9 0.4 5.9e-07 29.9 0.0 2.8 2 1 1 3 3 3 1 Immunoglobulin domain V-set PF07686.12 KFP04485.1 - 8.1e-08 32.1 0.2 0.038 13.8 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP04485.1 - 0.00071 19.4 0.2 0.0019 18.0 0.0 1.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP04485.1 - 0.0042 15.4 0.0 0.54 8.4 0.0 2.1 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E Herpes_gI PF01688.12 KFP04485.1 - 0.0098 15.0 0.1 0.72 8.9 0.0 2.6 2 1 0 2 2 2 1 Alphaherpesvirus glycoprotein I Receptor_2B4 PF11465.3 KFP04485.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 IQ PF00612.22 KFP04486.1 - 1.3e-05 24.4 0.5 1.8e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif RIIa PF02197.12 KFP04487.1 - 1.4e-13 50.0 0.6 1.7e-13 49.7 0.4 1.1 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF303 PF03629.13 KFP04488.1 - 2.1e-62 210.6 0.0 2.7e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF303) Innexin PF00876.13 KFP04489.1 - 7e-09 35.2 1.3 6.9e-08 31.9 0.9 2.0 1 1 0 1 1 1 1 Innexin PseudoU_synth_2 PF00849.17 KFP04490.1 - 4.8e-28 98.0 0.0 7.3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase PseudoU_synth_1 PF01416.15 KFP04491.1 - 1.8e-34 118.2 0.0 1.3e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase HYLS1_C PF15311.1 KFP04492.1 - 1.6e-15 57.0 0.2 1.8e-15 56.9 0.2 1.0 1 0 0 1 1 1 1 Hydrolethalus syndrome protein 1 C-terminus DEAD PF00270.24 KFP04493.1 - 1.5e-26 92.9 0.0 4.7e-26 91.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP04493.1 - 3.7e-23 81.1 0.3 6.6e-23 80.3 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KFP04493.1 - 0.01 15.7 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Pox_RNA_pol PF03293.9 KFP04493.1 - 0.05 13.1 0.0 0.23 10.9 0.0 2.1 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit AAA_19 PF13245.1 KFP04493.1 - 0.15 11.8 0.2 0.46 10.2 0.0 2.0 1 1 0 1 1 1 0 Part of AAA domain Ig_2 PF13895.1 KFP04494.1 - 2.4e-51 171.7 2.5 9.3e-12 44.9 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain I-set PF07679.11 KFP04494.1 - 1.2e-48 162.9 0.0 2.9e-11 43.0 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin I-set domain fn3 PF00041.16 KFP04494.1 - 1.2e-38 131.0 4.7 9.4e-16 57.7 0.1 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.1 KFP04494.1 - 1.6e-32 111.7 9.2 5.1e-08 33.3 0.1 6.0 5 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFP04494.1 - 6.6e-26 90.2 0.2 0.00043 20.3 0.0 6.5 5 1 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFP04494.1 - 1.1e-23 83.2 2.9 3.3e-05 23.7 0.0 7.8 5 3 0 5 5 5 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP04494.1 - 7.4e-09 35.3 2.3 0.022 14.6 0.0 5.3 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFP04494.1 - 0.0015 18.3 0.0 5 7.1 0.0 4.4 5 0 0 5 5 5 1 Penicillin-Binding Protein C-terminus Family Herpes_gE PF02480.11 KFP04494.1 - 0.0031 15.8 0.0 0.36 9.0 0.0 3.6 4 1 0 4 4 4 1 Alphaherpesvirus glycoprotein E Tissue_fac PF01108.12 KFP04494.1 - 0.0032 17.2 0.2 0.26 11.0 0.0 3.7 4 0 0 4 4 4 1 Tissue factor Protocadherin PF08374.6 KFP04494.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.1 KFP04494.1 - 0.025 14.9 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain STT3 PF02516.9 KFP04495.1 - 3.1e-145 484.8 45.6 1.4e-140 469.4 27.5 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 KFP04495.1 - 1.1e-06 28.6 16.8 1.1e-06 28.6 11.6 3.4 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase EI24 PF07264.6 KFP04496.1 - 5.8e-46 156.6 14.1 8.8e-46 156.0 9.8 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DAO PF01266.19 KFP04497.1 - 2.8e-24 85.7 0.0 5.8e-24 84.6 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase SRP-alpha_N PF04086.8 KFP04498.1 - 1.1e-66 225.1 12.2 1.6e-66 224.5 8.4 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KFP04498.1 - 4.5e-47 160.0 0.3 4e-46 156.9 0.2 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KFP04498.1 - 8.3e-08 32.2 2.1 1.3e-07 31.5 0.0 2.4 2 1 1 3 3 3 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KFP04498.1 - 1.8e-07 30.2 0.0 3.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KFP04498.1 - 3.2e-07 29.9 0.1 1.1e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KFP04498.1 - 0.0099 15.5 0.3 0.24 11.1 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFP04498.1 - 0.023 14.6 0.0 0.066 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KFP04498.1 - 0.038 14.1 0.1 0.36 10.9 0.0 2.6 3 1 0 3 3 3 0 AAA domain DUF2151 PF10221.4 KFP04498.1 - 0.041 12.0 5.8 0.063 11.4 4.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator AAA_33 PF13671.1 KFP04498.1 - 0.073 12.9 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ETF PF01012.16 KFP04498.1 - 0.23 11.1 3.0 2 8.0 0.1 2.4 2 0 0 2 2 2 0 Electron transfer flavoprotein domain SIR2_2 PF13289.1 KFP04499.1 - 1.1e-21 77.2 0.0 1.9e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 SIR2-like domain RFC1 PF08519.7 KFP04499.1 - 0.047 13.4 0.2 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain S6PP_C PF08472.5 KFP04499.1 - 0.088 12.4 0.0 0.83 9.2 0.0 2.4 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal TIR PF01582.15 KFP04500.1 - 2e-14 53.2 0.0 2.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.1 KFP04500.1 - 7e-14 51.8 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 TIR domain DcpS_C PF11969.3 KFP04501.1 - 4.3e-31 107.5 0.0 9.7e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KFP04501.1 - 4.6e-19 68.8 0.0 9.3e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Glyco_transf_29 PF00777.13 KFP04502.1 - 1.7e-73 247.0 0.0 2.1e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) DUF2753 PF10952.3 KFP04502.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) Ets PF00178.17 KFP04504.1 - 1.3e-39 134.1 0.7 1.3e-39 134.1 0.5 1.8 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFP04504.1 - 1.6e-26 91.8 0.1 3.8e-26 90.6 0.1 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain IRK PF01007.15 KFP04505.1 - 2.6e-151 503.2 2.6 2.8e-151 503.0 1.8 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP04505.1 - 0.22 11.2 7.1 0.75 9.5 5.0 1.9 1 1 1 2 2 2 0 Ion channel IRK PF01007.15 KFP04506.1 - 1.3e-166 553.5 1.0 1.6e-166 553.2 0.7 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP04506.1 - 0.002 17.8 8.7 0.0057 16.3 6.1 1.8 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 KFP04506.1 - 0.19 10.9 6.5 0.29 10.3 4.5 1.2 1 0 0 1 1 1 0 Ion transport protein Homeobox PF00046.24 KFP04507.1 - 2.6e-21 74.9 3.3 5e-21 74.0 2.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP04507.1 - 0.036 13.1 0.9 0.066 12.2 0.6 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Keratin PF02422.11 KFP04507.1 - 0.36 10.8 4.2 0.54 10.2 2.9 1.2 1 0 0 1 1 1 0 Keratin MSA-2c PF12238.3 KFP04507.1 - 1.8 8.1 9.1 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF716 PF04819.7 KFP04508.1 - 2.2e-37 127.5 8.0 3.8e-37 126.7 5.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) TnpB_IS66 PF05717.8 KFP04508.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 IS66 Orf2 like protein DUF716 PF04819.7 KFP04509.1 - 5.5e-32 110.0 4.9 5.5e-32 110.0 3.4 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF716) APP_E2 PF12925.2 KFP04511.1 - 2.3e-73 245.9 15.8 4.9e-73 244.8 11.0 1.5 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein APP_N PF02177.11 KFP04511.1 - 6.1e-42 141.7 0.3 2.6e-41 139.7 0.2 2.2 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding APP_amyloid PF10515.4 KFP04511.1 - 2.5e-30 104.4 1.0 6.6e-30 103.1 0.2 2.3 2 0 0 2 2 2 1 beta-amyloid precursor protein C-terminus APP_Cu_bd PF12924.2 KFP04511.1 - 8.2e-28 96.6 9.4 1.3e-27 96.0 4.3 2.8 2 0 0 2 2 2 1 Copper-binding of amyloid precursor, CuBD Kunitz_BPTI PF00014.18 KFP04511.1 - 4.8e-20 71.5 5.7 4.8e-20 71.5 3.9 2.0 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain zf-C2H2 PF00096.21 KFP04512.1 - 1.2e-30 103.9 79.7 0.00039 20.5 1.9 10.7 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04512.1 - 4.1e-24 83.0 65.8 0.0087 16.3 2.9 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP04512.1 - 1.4e-16 59.8 67.4 0.0015 18.6 1.0 11.8 11 1 0 11 11 11 8 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP04512.1 - 2.2e-15 56.2 55.7 0.00069 19.6 0.0 10.1 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP04512.1 - 3.7e-10 39.3 45.7 0.012 15.4 0.4 8.8 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFP04512.1 - 1.6e-08 34.6 46.5 0.21 11.7 0.2 9.4 5 2 2 8 8 8 5 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFP04512.1 - 7.2e-06 26.0 2.5 0.0021 18.1 0.0 9.3 9 0 0 9 9 9 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP04512.1 - 3.3e-05 23.9 40.1 0.028 14.5 1.0 7.8 7 1 1 8 8 8 4 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 KFP04512.1 - 4.2 5.7 41.4 0.21 10.0 0.7 6.8 6 2 1 7 7 7 0 Protein of unknown function (DUF629) NFRKB_winged PF14465.1 KFP04513.1 - 1.2e-35 121.3 0.6 9.8e-35 118.4 0.6 2.4 2 0 0 2 2 2 1 NFRKB Winged Helix-like Trypsin PF00089.21 KFP04514.1 - 8.4e-65 218.4 0.1 1.4e-64 217.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 KFP04514.1 - 1e-36 125.3 0.3 7.1e-20 71.1 0.3 2.6 2 0 0 2 2 2 2 CUB domain Ldl_recept_a PF00057.13 KFP04514.1 - 1.5e-36 123.9 82.0 1.3e-10 41.0 9.4 4.8 5 0 0 5 5 5 4 Low-density lipoprotein receptor domain class A SEA PF01390.15 KFP04514.1 - 2.7e-18 65.6 0.1 9.1e-18 63.9 0.0 1.9 2 0 0 2 2 2 1 SEA domain DUF1986 PF09342.6 KFP04514.1 - 8.7e-06 25.2 0.1 2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB_2 PF02408.15 KFP04514.1 - 4.9e-05 22.8 2.2 0.00013 21.5 0.7 2.2 2 0 0 2 2 2 1 CUB-like domain DUF2909 PF11137.3 KFP04514.1 - 0.055 13.2 0.4 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Fascin PF06268.8 KFP04516.1 - 1.6e-68 227.8 0.5 3.8e-24 84.9 0.1 3.0 3 0 0 3 3 3 3 Fascin domain FRG1 PF06229.7 KFP04516.1 - 1.2e-10 41.1 2.1 0.0026 17.2 0.0 4.7 2 2 2 5 5 5 4 FRG1-like family DUF4430 PF14478.1 KFP04516.1 - 0.072 13.1 1.5 1.7 8.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4430) Actin PF00022.14 KFP04517.1 - 4.2e-162 539.0 0.0 4.7e-162 538.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFP04517.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) F-box-like PF12937.2 KFP04519.1 - 2.4e-07 30.3 1.2 2.4e-07 30.3 0.9 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KFP04519.1 - 5.8e-07 29.0 1.6 5.8e-07 29.0 1.1 2.7 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 KFP04519.1 - 0.00044 19.7 16.9 0.018 14.6 0.4 6.1 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP04519.1 - 0.0035 17.0 0.9 0.0035 17.0 0.6 6.5 5 3 0 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 KFP04519.1 - 0.21 11.9 21.2 0.63 10.4 0.7 7.6 8 1 0 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 KFP04519.1 - 4 7.8 21.3 0.39 10.9 0.8 5.9 5 1 0 5 5 5 0 Leucine Rich Repeat Nucleoside_tran PF01733.13 KFP04520.1 - 2.1e-49 168.3 4.2 2.1e-49 168.3 2.9 2.1 2 1 0 2 2 2 1 Nucleoside transporter WD40 PF00400.27 KFP04521.1 - 5.7e-07 29.1 0.2 0.1 12.5 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat HlyIII PF03006.15 KFP04522.1 - 4.2e-45 153.8 19.3 4.8e-45 153.6 13.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related DIL PF01843.14 KFP04523.1 - 2.7e-22 78.6 0.9 5.2e-22 77.7 0.6 1.5 1 0 0 1 1 1 1 DIL domain RA PF00788.18 KFP04523.1 - 2e-17 63.4 0.0 3.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PDZ PF00595.19 KFP04523.1 - 7e-12 45.3 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP04523.1 - 0.00016 21.5 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SPG48 PF14764.1 KFP04524.1 - 4.4e-180 599.0 11.6 4.4e-180 599.0 8.0 1.6 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking Fork_head PF00250.13 KFP04525.1 - 1.4e-41 140.4 0.3 2.1e-41 139.8 0.2 1.3 1 0 0 1 1 1 1 Fork head domain p450 PF00067.17 KFP04526.1 - 1e-125 419.8 0.1 1.2e-125 419.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFP04527.1 - 4e-115 384.9 0.4 4.5e-115 384.8 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 CARD PF00619.16 KFP04528.1 - 6.9e-21 73.8 0.0 2.2e-20 72.2 0.0 2.0 1 0 0 1 1 1 1 Caspase recruitment domain PDZ PF00595.19 KFP04528.1 - 1.3e-06 28.5 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Guanylate_kin PF00625.16 KFP04528.1 - 3.6e-05 23.2 0.1 3.6e-05 23.2 0.1 2.7 2 0 0 2 2 2 1 Guanylate kinase Peptidase_M54 PF07998.6 KFP04529.1 - 6.4e-06 26.0 1.3 8.1e-05 22.4 2.2 1.8 2 0 0 2 2 2 1 Peptidase family M54 Peptidase_M10 PF00413.19 KFP04529.1 - 0.055 13.1 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Matrixin HEAT PF02985.17 KFP04530.1 - 5.6e-10 38.4 4.3 0.012 15.6 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 KFP04530.1 - 1.2e-07 31.8 0.2 0.00016 21.8 0.0 3.9 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 KFP04530.1 - 0.00045 20.6 0.1 0.73 10.4 0.0 5.0 4 1 1 5 5 5 1 HEAT-like repeat DUF2435 PF10363.4 KFP04530.1 - 0.039 13.8 0.0 0.22 11.4 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) DNA_Packaging_2 PF11123.3 KFP04530.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 DNA packaging protein Daxx PF03344.10 KFP04530.1 - 0.3 9.5 0.0 0.44 8.9 0.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF972 PF06156.8 KFP04531.1 - 0.013 15.8 24.7 0.073 13.4 3.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 KFP04531.1 - 0.018 14.5 20.0 0.74 9.3 3.5 3.8 3 1 0 3 3 3 0 Septum formation initiator DUF3212 PF11486.3 KFP04531.1 - 0.043 13.5 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) DUF664 PF04978.7 KFP04531.1 - 0.082 13.1 0.5 0.17 12.0 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF664) Phage_GP20 PF06810.6 KFP04531.1 - 0.1 12.0 25.5 2.8 7.3 2.8 3.2 1 1 2 3 3 3 0 Phage minor structural protein GP20 ADIP PF11559.3 KFP04531.1 - 0.12 12.2 23.4 0.78 9.6 6.3 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 KFP04531.1 - 0.18 11.6 25.9 3.1 7.6 3.1 2.4 1 1 1 2 2 2 0 Tropomyosin like MHC2-interact PF09307.5 KFP04531.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.9 5 0 0 5 5 5 0 CLIP, MHC2 interacting APG6 PF04111.7 KFP04531.1 - 0.35 9.8 26.1 4.5 6.2 8.7 2.6 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-Q PF13094.1 KFP04531.1 - 0.44 10.5 26.6 0.3 11.0 3.3 3.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4254 PF14063.1 KFP04531.1 - 0.75 9.3 11.4 0.75 9.3 3.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) SlyX PF04102.7 KFP04531.1 - 1 9.7 18.8 0.21 11.9 1.5 3.5 2 1 1 3 3 3 0 SlyX Allexi_40kDa PF05549.6 KFP04531.1 - 1.2 8.3 9.2 0.15 11.3 3.0 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein IncA PF04156.9 KFP04531.1 - 1.5 8.3 21.7 1.9 8.0 6.4 2.3 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 KFP04531.1 - 2.1 7.8 25.0 1.4 8.4 1.1 3.2 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mod_r PF07200.8 KFP04531.1 - 2.1 8.2 23.3 24 4.8 8.5 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Chibby PF14645.1 KFP04531.1 - 2.2 8.2 12.2 0.13 12.1 1.1 2.6 2 1 0 2 2 2 0 Chibby family DUF1049 PF06305.6 KFP04531.1 - 2.3 7.7 10.4 2.2 7.8 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) Seryl_tRNA_N PF02403.17 KFP04531.1 - 3 7.9 24.1 3.7 7.6 3.5 3.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3166 PF11365.3 KFP04531.1 - 3.9 8.0 14.1 6.9 7.1 1.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) DUF641 PF04859.7 KFP04531.1 - 3.9 7.2 23.6 7.6 6.2 3.0 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) ATG16 PF08614.6 KFP04531.1 - 6.1 6.6 28.9 4.7 6.9 6.5 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Tweety PF04906.8 KFP04532.1 - 4.8e-171 568.6 11.7 5.8e-171 568.3 8.1 1.0 1 0 0 1 1 1 1 Tweety DUF4131 PF13567.1 KFP04532.1 - 0.0066 15.8 7.8 0.034 13.5 0.7 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) DUF2721 PF11026.3 KFP04532.1 - 0.0094 15.5 0.2 0.0094 15.5 0.2 2.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2721) CitMHS PF03600.11 KFP04532.1 - 0.03 12.9 0.6 0.064 11.8 0.4 1.5 1 0 0 1 1 1 0 Citrate transporter Pex24p PF06398.6 KFP04532.1 - 0.056 12.2 0.0 0.34 9.6 0.0 2.1 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Prominin PF05478.6 KFP04532.1 - 0.062 10.8 13.5 0.023 12.2 1.7 2.7 2 1 1 3 3 3 0 Prominin DUF2207 PF09972.4 KFP04532.1 - 5.7 5.4 5.8 9.5 4.6 2.9 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Fringe PF02434.11 KFP04533.1 - 4.8e-107 356.8 0.0 5.4e-107 356.7 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KFP04533.1 - 0.00059 19.4 0.0 0.00085 18.9 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glyco_tranf_2_4 PF13704.1 KFP04533.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Gal-bind_lectin PF00337.17 KFP04534.1 - 1.7e-35 121.2 0.1 1.8e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 Galactoside-binding lectin 7tm_1 PF00001.16 KFP04535.1 - 4.4e-46 157.0 16.9 5.1e-46 156.9 11.7 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP04535.1 - 0.0043 16.2 8.4 0.0098 15.0 5.8 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFP04535.1 - 0.0062 15.6 17.4 0.02 13.9 12.1 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.10 KFP04535.1 - 0.0095 15.7 2.8 0.0095 15.7 1.9 2.3 1 1 1 2 2 2 1 Caenorhabditis serpentine receptor-like protein, class xa Git3 PF11710.3 KFP04535.1 - 8.6 5.8 12.5 0.22 11.0 4.3 1.7 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Sulfotransfer_2 PF03567.9 KFP04536.1 - 3.4e-64 216.9 2.3 5e-64 216.4 1.6 1.3 1 0 0 1 1 1 1 Sulfotransferase family eIF2A PF08662.6 KFP04537.1 - 6.2e-73 244.6 7.6 4.5e-67 225.5 1.4 4.4 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KFP04537.1 - 1.2e-06 27.9 0.1 2.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP04537.1 - 0.00011 21.9 0.1 0.00035 20.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.7 KFP04537.1 - 0.0013 16.6 0.3 0.53 8.0 0.1 2.4 1 1 0 2 2 2 2 IKI3 family WD40 PF00400.27 KFP04537.1 - 0.0031 17.3 4.6 27 4.8 0.0 5.7 7 0 0 7 7 7 0 WD domain, G-beta repeat RRM_6 PF14259.1 KFP04537.1 - 0.0055 16.6 0.0 0.029 14.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KFP04537.1 - 0.05 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PX PF00787.19 KFP04538.1 - 1.8e-21 76.0 2.1 1.8e-21 76.0 1.5 2.0 2 1 0 2 2 2 1 PX domain EPSP_synthase PF00275.15 KFP04538.1 - 0.097 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TMPIT PF07851.8 KFP04538.1 - 0.39 9.7 6.5 0.2 10.6 3.0 1.5 2 0 0 2 2 2 0 TMPIT-like protein NUDIX PF00293.23 KFP04539.1 - 6.8e-17 61.3 0.0 8.5e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain FtsJ PF01728.14 KFP04540.1 - 7.9e-54 182.3 0.0 1e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase TPIP1 PF15338.1 KFP04540.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 MAD PF05557.8 KFP04541.1 - 5.9e-238 791.6 101.4 6.7e-238 791.4 70.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein TSC22 PF01166.13 KFP04541.1 - 0.00046 20.0 6.4 0.00046 20.0 4.4 10.5 7 2 3 11 11 11 3 TSC-22/dip/bun family LRR_8 PF13855.1 KFP04542.1 - 1.4e-24 85.6 5.9 1.2e-14 53.7 0.2 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP04542.1 - 2e-13 49.5 10.1 2.9e-05 23.5 0.3 3.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04542.1 - 3.3e-09 35.4 8.1 0.39 10.9 0.0 5.8 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_5 PF13306.1 KFP04542.1 - 1.9e-08 34.0 0.1 5.7e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFP04542.1 - 4.4e-06 26.2 7.5 3.9 7.8 0.1 5.9 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 KFP04542.1 - 0.44 10.9 9.1 13 6.5 0.2 5.2 5 1 0 5 5 5 0 Leucine rich repeat DUF2372 PF10178.4 KFP04543.1 - 9e-31 105.8 0.1 1.5e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Solute_trans_a PF03619.11 KFP04544.1 - 4.2e-98 328.0 21.3 5.5e-98 327.6 14.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha bZIP_Maf PF03131.12 KFP04545.1 - 1.1e-34 118.5 12.5 1.4e-34 118.2 8.7 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 KFP04545.1 - 0.00019 20.8 5.4 0.00019 20.8 3.7 2.2 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 KFP04545.1 - 0.0061 16.4 16.7 0.14 12.1 11.5 2.4 1 1 0 1 1 1 1 bZIP transcription factor Spc24 PF08286.6 KFP04545.1 - 0.012 15.2 0.4 0.012 15.2 0.3 1.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1192 PF06698.6 KFP04545.1 - 0.018 14.8 8.2 0.048 13.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2046 PF09755.4 KFP04545.1 - 0.019 13.8 6.2 0.028 13.3 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF972 PF06156.8 KFP04545.1 - 0.034 14.4 2.2 0.034 14.4 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tox-ODYAM1 PF15642.1 KFP04545.1 - 0.041 12.5 2.1 0.048 12.3 1.4 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus HGTP_anticodon2 PF12745.2 KFP04545.1 - 0.067 12.3 3.9 0.075 12.1 2.7 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Mnd1 PF03962.10 KFP04545.1 - 0.081 12.5 2.4 0.11 12.1 1.7 1.3 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 KFP04545.1 - 0.082 11.3 2.6 0.087 11.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFP04545.1 - 0.16 10.9 6.4 0.2 10.6 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 KFP04545.1 - 0.23 11.3 15.9 0.24 11.2 9.3 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DUF4164 PF13747.1 KFP04545.1 - 0.42 10.7 8.4 0.096 12.8 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Uds1 PF15456.1 KFP04545.1 - 0.48 10.4 8.0 1.3 9.0 1.0 2.3 1 1 1 2 2 2 0 Up-regulated During Septation Microtub_assoc PF07989.6 KFP04545.1 - 0.6 9.9 8.3 1.8 8.4 5.8 1.8 1 1 0 1 1 1 0 Microtubule associated IncA PF04156.9 KFP04545.1 - 0.97 8.9 9.8 3.7 7.1 6.8 1.8 1 1 0 1 1 1 0 IncA protein Mst1_SARAH PF11629.3 KFP04545.1 - 1.3 8.9 6.1 14 5.6 0.1 2.7 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 HALZ PF02183.13 KFP04545.1 - 1.9 8.2 9.1 0.94 9.2 3.3 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 KFP04545.1 - 5.9 7.2 12.2 29 5.0 8.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 KFP04545.1 - 6.4 7.2 9.3 5.6 7.4 3.0 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) XkdW PF09636.5 KFP04545.1 - 7.1 6.5 6.4 5.1 7.0 1.7 2.1 1 1 1 2 2 2 0 XkdW protein Glyco_hydro_31 PF01055.21 KFP04546.1 - 7.4e-172 572.1 0.0 8.7e-172 571.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFP04546.1 - 1.6e-08 34.2 0.1 1.5e-07 31.1 0.0 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like DUF3677 PF12432.3 KFP04547.1 - 2.8e-29 101.3 2.0 2.8e-29 101.3 1.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3677) UNC45-central PF11701.3 KFP04547.1 - 0.29 10.7 5.4 2.2 7.9 0.1 4.0 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central DUF3585 PF12130.3 KFP04548.1 - 2.4e-45 153.8 24.2 4e-45 153.1 16.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) CH PF00307.26 KFP04548.1 - 5.7e-20 71.3 0.1 1.8e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP04548.1 - 6.1e-11 41.8 0.1 1.7e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 CAMSAP CH domain LIM PF00412.17 KFP04548.1 - 8.8e-06 25.7 4.5 2.7e-05 24.1 3.2 1.8 1 0 0 1 1 1 1 LIM domain zf-AN1 PF01428.11 KFP04549.1 - 8.2e-22 76.8 22.5 1.9e-13 50.0 6.3 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger FYVE PF01363.16 KFP04549.1 - 0.047 13.5 2.7 0.047 13.5 1.9 2.5 2 1 0 2 2 2 0 FYVE zinc finger zf-C3HC PF07967.8 KFP04549.1 - 0.066 12.9 6.9 0.085 12.6 0.7 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like zf-dskA_traR PF01258.12 KFP04549.1 - 0.17 11.6 5.3 24 4.7 0.1 3.5 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zinc_ribbon_4 PF13717.1 KFP04549.1 - 0.36 10.5 9.4 4.1 7.1 0.7 3.8 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 KFP04549.1 - 0.39 10.6 24.5 15 5.5 11.7 3.5 1 1 1 2 2 2 0 IBR domain Transp_Tc5_C PF04236.10 KFP04549.1 - 1.4 9.1 17.6 2 8.7 4.8 2.7 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain 7tm_1 PF00001.16 KFP04550.1 - 2.2e-46 158.1 17.3 2.8e-46 157.7 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04550.1 - 7.1e-05 22.0 16.1 9.6e-05 21.6 11.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFP04550.1 - 0.019 14.7 3.4 0.019 14.7 2.4 2.8 1 1 0 2 2 2 0 Olfactory receptor 7tm_1 PF00001.16 KFP04552.1 - 2.4e-16 59.6 17.5 3.6e-16 59.0 12.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Col_cuticle_N PF01484.12 KFP04552.1 - 0.73 9.5 0.0 0.73 9.5 0.0 3.2 4 0 0 4 4 4 0 Nematode cuticle collagen N-terminal domain DUF2373 PF10180.4 KFP04553.1 - 6.1e-22 76.9 0.2 8.3e-22 76.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) p450 PF00067.17 KFP04554.1 - 1.4e-124 416.1 0.7 1.6e-124 415.9 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFP04555.1 - 1e-118 396.8 0.6 1.2e-118 396.6 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 ArfGap PF01412.13 KFP04556.1 - 2.9e-27 94.7 0.1 5.2e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 KFP04556.1 - 3.3e-16 59.3 0.7 6.4e-09 35.9 0.3 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 KFP04556.1 - 2e-14 53.7 0.5 2e-09 37.6 0.1 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFP04556.1 - 0.00011 22.2 4.2 0.083 12.9 0.1 2.9 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 KFP04556.1 - 0.0014 18.5 0.2 0.33 10.8 0.0 2.8 3 0 0 3 3 3 1 PH domain Mcp5_PH PF12814.2 KFP04556.1 - 0.014 15.3 0.0 0.041 13.7 0.0 1.9 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology DUF410 PF04190.8 KFP04557.1 - 1.5e-85 286.9 0.1 9.4e-84 281.0 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF410) Sad1_UNC PF07738.8 KFP04558.1 - 1.1e-44 151.5 0.0 4.6e-44 149.4 0.0 2.0 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal MRP PF09387.5 KFP04558.1 - 7.9e-18 64.8 5.3 8.5e-17 61.5 3.6 2.2 1 1 0 1 1 1 1 Mitochondrial RNA binding protein MRP FlaC_arch PF05377.6 KFP04558.1 - 0.7 9.8 12.6 1 9.2 2.3 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) HEAT_2 PF13646.1 KFP04559.1 - 1.2e-16 60.7 0.0 6.1e-05 23.2 0.0 6.5 3 2 3 6 6 6 5 HEAT repeats Vac14_Fab1_bd PF12755.2 KFP04559.1 - 1.3e-09 38.3 0.4 0.033 14.5 0.0 5.1 4 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFP04559.1 - 9e-08 32.3 19.0 0.27 11.8 0.2 8.2 9 0 0 9 9 9 3 HEAT-like repeat Cnd1 PF12717.2 KFP04559.1 - 5.8e-06 26.2 3.0 0.47 10.2 0.2 5.2 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFP04559.1 - 2.1e-05 24.0 9.8 0.16 11.2 0.0 4.9 4 2 1 5 5 5 2 CLASP N terminal HEAT PF02985.17 KFP04559.1 - 0.0002 21.1 31.8 0.46 10.6 0.0 10.1 12 0 0 12 12 12 4 HEAT repeat DUF3535 PF12054.3 KFP04559.1 - 0.0024 16.5 0.0 0.011 14.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) cNMP_binding PF00027.24 KFP04560.1 - 6.1e-45 150.9 0.1 3.8e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KFP04560.1 - 1.1e-13 50.3 0.1 2.1e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit GXGXG PF01493.14 KFP04560.1 - 0.0052 15.8 0.1 0.14 11.1 0.0 2.1 2 0 0 2 2 2 1 GXGXG motif PDGF PF00341.12 KFP04561.1 - 2.7e-21 75.4 9.9 4.1e-21 74.8 6.9 1.3 1 0 0 1 1 1 1 PDGF/VEGF domain PDGF_N PF04692.8 KFP04561.1 - 3.4e-09 37.0 1.2 4.6e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 Platelet-derived growth factor, N terminal region Fork_head PF00250.13 KFP04562.1 - 3.3e-38 129.6 0.2 4e-38 129.3 0.2 1.0 1 0 0 1 1 1 1 Fork head domain DUF1193 PF06702.7 KFP04563.1 - 1.1e-113 378.1 0.3 1.4e-113 377.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) FAT PF02259.18 KFP04565.1 - 3.4e-67 226.9 10.7 1.1e-66 225.2 6.7 2.5 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KFP04565.1 - 1.7e-13 50.5 0.1 5.6e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFP04565.1 - 9.5e-05 21.7 0.1 0.00038 19.8 0.1 2.2 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 KFP04565.1 - 0.77 9.8 5.5 4.4 7.4 0.6 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP04565.1 - 1.8 8.5 6.9 20 5.2 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PKD PF00801.15 KFP04566.1 - 0.00062 19.4 1.0 2.7 7.7 0.0 3.3 3 0 0 3 3 3 2 PKD domain Pentaxin PF00354.12 KFP04567.1 - 8.8e-38 129.6 0.0 1.3e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFP04567.1 - 1.8e-14 54.2 0.0 2.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SlyX PF04102.7 KFP04567.1 - 0.0023 18.2 5.0 0.89 9.9 0.0 2.9 3 0 0 3 3 3 2 SlyX Laminin_G_2 PF02210.19 KFP04567.1 - 0.0078 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Atg14 PF10186.4 KFP04567.1 - 0.13 11.1 5.4 0.55 9.1 0.1 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GOLGA2L5 PF15070.1 KFP04567.1 - 0.14 10.6 5.4 0.21 10.0 3.8 1.3 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 CCDC-167 PF15188.1 KFP04567.1 - 0.15 12.0 1.7 0.37 10.7 1.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Pox_A_type_inc PF04508.7 KFP04567.1 - 1.7 8.6 10.4 12 5.9 0.0 3.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CtIP_N PF10482.4 KFP04567.1 - 3.5 7.4 6.2 0.94 9.2 1.2 1.9 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Actin PF00022.14 KFP04568.1 - 1.7e-161 537.0 0.0 1.9e-161 536.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFP04568.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ubiquitin PF00240.18 KFP04570.1 - 5.3e-08 32.1 0.0 1.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KFP04570.1 - 9.5e-07 28.4 0.1 2.8e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KFP04570.1 - 0.0011 18.5 0.0 0.0029 17.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 KFP04570.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF4589 PF15252.1 KFP04570.1 - 3.7 7.2 7.7 4.4 7.0 4.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4589) Sema PF01403.14 KFP04571.1 - 7.6e-26 90.6 0.0 8.4e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Sema domain p450 PF00067.17 KFP04572.1 - 3.5e-23 81.8 0.2 3.7e-23 81.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 PKD PF00801.15 KFP04573.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 PKD domain Polysacc_lyase PF14099.1 KFP04573.1 - 0.061 12.9 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase RBP_receptor PF14752.1 KFP04574.1 - 2.7e-240 798.9 23.2 3.1e-240 798.7 16.1 1.0 1 0 0 1 1 1 1 Retinol binding protein receptor LRR_8 PF13855.1 KFP04575.1 - 3.4e-24 84.3 9.9 3.3e-13 49.1 2.5 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFP04575.1 - 8e-20 70.0 21.3 5.9e-07 28.9 0.0 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04575.1 - 1.9e-10 39.2 5.9 0.026 14.4 0.1 4.8 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFP04575.1 - 1.5e-07 30.4 8.0 0.091 13.0 0.0 5.2 5 1 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 KFP04575.1 - 3.9e-05 23.2 0.1 8.8e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.1 KFP04575.1 - 7.4e-05 22.4 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFP04575.1 - 0.00069 19.4 11.7 0.12 12.5 0.1 5.1 4 1 1 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.1 KFP04576.1 - 8.1e-21 73.5 7.0 3.3e-11 42.7 0.4 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFP04576.1 - 5.4e-14 51.4 12.7 8.4e-07 28.4 0.0 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04576.1 - 4.5e-09 35.0 6.8 0.031 14.2 0.1 5.2 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.1 KFP04576.1 - 3.5e-08 33.2 1.5 7.9e-05 22.2 0.1 1.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 KFP04576.1 - 2.9e-06 26.5 6.7 0.18 12.1 0.0 5.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_5 PF13306.1 KFP04576.1 - 6.3e-06 25.9 0.1 1.1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFP04576.1 - 0.00026 20.7 12.6 0.43 10.8 0.2 4.6 4 2 1 5 5 5 3 Leucine Rich repeat NosD PF05048.8 KFP04576.1 - 0.017 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Baculo_PEP_N PF04512.7 KFP04576.1 - 0.11 12.4 0.2 0.31 11.0 0.1 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Zona_pellucida PF00100.18 KFP04577.1 - 1.5e-46 159.0 0.0 1.7e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Zona_pellucida PF00100.18 KFP04578.1 - 9.8e-49 166.1 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain BA14K PF07886.6 KFP04578.1 - 0.048 13.3 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 BA14K-like protein Dymeclin PF09742.4 KFP04579.1 - 4e-13 48.3 1.2 4.1e-13 48.3 0.8 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein V-set PF07686.12 KFP04581.1 - 2.4e-19 69.3 1.2 3.5e-14 52.6 0.0 4.4 1 1 3 4 4 4 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP04581.1 - 1.1e-16 60.6 5.5 9.6e-10 38.4 0.2 3.7 3 1 0 3 3 3 2 Immunoglobulin domain I-set PF07679.11 KFP04581.1 - 1.5e-12 47.1 0.1 6.4e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFP04581.1 - 6.5e-12 45.3 3.1 3.7e-05 23.7 0.1 4.1 3 1 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFP04581.1 - 1.3e-11 44.8 8.9 1.1e-08 35.4 0.2 4.0 3 1 0 3 3 3 2 Immunoglobulin domain DcuC PF03606.10 KFP04581.1 - 0.022 12.9 0.0 0.043 12.0 0.0 1.4 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier EphA2_TM PF14575.1 KFP04581.1 - 0.025 14.9 0.2 0.055 13.8 0.1 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain C2-set_2 PF08205.7 KFP04581.1 - 0.028 14.2 0.1 0.078 12.8 0.1 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain DUF3619 PF12279.3 KFP04581.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) FAM163 PF15069.1 KFP04581.1 - 0.076 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 FAM163 family DUF1510 PF07423.6 KFP04581.1 - 0.094 12.0 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2500 PF10694.4 KFP04581.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) PIRT PF15099.1 KFP04581.1 - 0.61 9.3 3.0 0.43 9.7 0.5 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family RIIa PF02197.12 KFP04582.1 - 0.026 13.9 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Tetraspannin PF00335.15 KFP04583.1 - 4.5e-33 114.3 8.2 5.6e-33 114.0 5.7 1.1 1 0 0 1 1 1 1 Tetraspanin family UPF0220 PF05255.6 KFP04583.1 - 1.6 7.9 8.2 3.4 6.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0220) CD20 PF04103.10 KFP04583.1 - 4.7 7.1 11.6 0.42 10.5 4.7 1.8 2 1 0 2 2 2 0 CD20-like family RhoGAP PF00620.22 KFP04584.1 - 6.6e-32 110.2 0.4 1.7e-31 108.9 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain GAGA_bind PF06217.7 KFP04584.1 - 0.11 12.3 7.7 0.024 14.6 0.5 2.6 2 0 0 2 2 2 0 GAGA binding protein-like family Glyco_transf_43 PF03360.11 KFP04585.1 - 1.4e-76 256.6 0.0 1.6e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glyco_transf_7N PF13733.1 KFP04586.1 - 1.5e-55 186.2 0.4 2.4e-55 185.6 0.3 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.9 KFP04586.1 - 4.1e-28 96.6 0.4 1.3e-27 95.0 0.2 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP04586.1 - 5.6e-08 32.2 0.1 0.0001 21.4 0.0 2.4 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Phycoerythr_ab PF02972.9 KFP04586.1 - 0.027 14.0 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Phycoerythrin, alpha/beta chain Tmp39 PF10271.4 KFP04587.1 - 1.4e-180 600.5 17.5 1.6e-180 600.3 12.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein Amidase PF01425.16 KFP04588.1 - 2.6e-92 310.0 0.0 3.3e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Amidase SNF2_N PF00176.18 KFP04589.1 - 8.5e-67 225.0 0.2 1.4e-66 224.3 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFP04589.1 - 2.5e-10 40.4 0.0 1.2e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFP04589.1 - 6.8e-09 35.4 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP04589.1 - 1e-07 31.6 0.0 2.7e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFP04589.1 - 4.8e-05 22.3 0.2 0.00035 19.4 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 KFP04589.1 - 0.0025 17.9 0.0 0.0099 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain TT_ORF2 PF02957.10 KFP04589.1 - 0.068 13.8 0.7 0.18 12.4 0.5 1.7 1 0 0 1 1 1 0 TT viral ORF2 Strabismus PF06638.6 KFP04590.1 - 4.6e-267 886.2 0.2 5.4e-267 886.0 0.2 1.0 1 0 0 1 1 1 1 Strabismus protein Virul_fac_BrkB PF03631.10 KFP04590.1 - 0.04 13.2 9.3 0.017 14.5 4.7 1.5 2 0 0 2 2 2 0 Virulence factor BrkB Calsequestrin PF01216.12 KFP04591.1 - 1.1e-209 695.8 47.8 7.8e-209 693.0 33.2 2.0 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_6 PF13848.1 KFP04591.1 - 1.1e-20 74.2 3.9 2.4e-18 66.5 1.6 2.3 2 1 0 2 2 2 2 Thioredoxin-like domain CDC45 PF02724.9 KFP04591.1 - 0.78 7.6 19.5 1.1 7.1 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KFP04591.1 - 1.7 6.4 21.3 2.1 6.1 14.8 1.2 1 0 0 1 1 1 0 Nop14-like family Sugar_tr PF00083.19 KFP04592.1 - 3.5e-31 108.2 15.3 4.8e-31 107.8 10.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP04592.1 - 1.5e-27 96.2 43.1 4.4e-25 88.1 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mab-21 PF03281.9 KFP04593.1 - 4.5e-71 239.3 7.1 5.9e-71 238.9 5.0 1.1 1 0 0 1 1 1 1 Mab-21 protein MAR_sialic_bdg PF10564.4 KFP04593.1 - 0.38 10.5 2.3 0.48 10.2 0.6 2.0 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat Yae1_N PF09811.4 KFP04594.1 - 4.3e-15 54.9 58.7 0.00052 19.4 6.8 5.7 3 2 0 3 3 3 3 Essential protein Yae1, N terminal E1-E2_ATPase PF00122.15 KFP04595.1 - 3e-60 203.1 1.3 5.4e-60 202.2 0.9 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFP04595.1 - 7.4e-44 149.4 0.3 7.4e-44 149.4 0.2 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFP04595.1 - 5.2e-31 108.7 0.0 5.2e-30 105.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP04595.1 - 3.4e-26 91.0 0.0 1.2e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFP04595.1 - 3.9e-19 67.8 0.0 7.6e-19 66.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFP04595.1 - 1e-14 55.1 0.0 5.6e-14 52.7 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFP04595.1 - 4.8e-06 26.3 0.9 0.00081 19.0 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Sdh_cyt PF01127.17 KFP04595.1 - 0.002 17.9 0.6 2.4 7.9 0.8 2.5 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF742 PF05331.6 KFP04595.1 - 0.094 12.3 0.0 12 5.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF742) V-set PF07686.12 KFP04596.1 - 4.3e-08 33.0 0.0 1.7e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP04596.1 - 5.9e-07 29.5 0.1 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP04596.1 - 1.8e-06 27.6 0.2 6.5e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 KFP04596.1 - 6.9e-06 26.0 0.1 0.0016 18.5 0.1 2.6 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFP04596.1 - 0.00077 19.9 0.8 0.12 12.9 0.0 2.5 2 1 0 2 2 2 1 Immunoglobulin domain Receptor_2B4 PF11465.3 KFP04596.1 - 0.024 14.5 0.1 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Lipase PF00151.14 KFP04597.1 - 2.1e-93 313.1 0.0 3.2e-93 312.5 0.0 1.2 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.2 KFP04597.1 - 5.9e-06 26.3 0.9 7.9e-06 25.9 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP04597.1 - 0.0099 15.6 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFP04597.1 - 0.09 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Popeye PF04831.8 KFP04598.1 - 3.5e-76 254.1 0.1 4.5e-76 253.7 0.1 1.1 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.24 KFP04598.1 - 5.7e-05 22.8 0.0 0.00055 19.6 0.0 2.5 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain PaaSYMP PF14738.1 KFP04599.1 - 1.2e-57 193.9 7.3 2.1e-57 193.1 5.1 1.4 1 0 0 1 1 1 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 DASH_Spc19 PF08287.6 KFP04599.1 - 1.8 8.1 8.2 2.5 7.7 5.7 1.2 1 0 0 1 1 1 0 Spc19 Pkinase PF00069.20 KFP04600.1 - 1.4e-64 217.7 0.0 1.7e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04600.1 - 2.3e-24 85.8 0.0 3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP04600.1 - 5e-06 25.6 0.0 4.9e-05 22.4 0.0 2.0 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 KFP04600.1 - 0.004 16.9 0.0 0.0086 15.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP04600.1 - 0.044 13.3 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase 7tm_3 PF00003.17 KFP04601.1 - 1e-20 74.1 15.7 1.4e-20 73.7 10.9 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2628 PF10947.3 KFP04601.1 - 1.3 8.8 5.9 0.19 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) LRR_8 PF13855.1 KFP04602.1 - 2.7e-28 97.4 34.3 8.9e-12 44.5 2.2 2.8 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 KFP04602.1 - 4.5e-22 77.2 21.2 1.3e-11 43.8 0.1 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04602.1 - 5e-11 41.0 16.0 0.0027 17.4 0.0 5.5 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 KFP04602.1 - 1.8e-07 30.1 14.1 0.65 10.4 0.0 6.0 7 0 0 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 KFP04602.1 - 0.013 15.4 9.5 19 5.7 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat NDUF_B4 PF07225.7 KFP04603.1 - 7.5e-55 184.0 0.7 8.3e-55 183.9 0.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HgmA PF04209.8 KFP04604.1 - 4.6e-204 677.6 0.0 5.2e-204 677.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ras PF00071.17 KFP04605.1 - 1.6e-13 50.3 0.0 5.7e-13 48.5 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFP04605.1 - 3e-12 47.1 0.0 1.6e-10 41.5 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFP04605.1 - 6.9e-06 26.0 0.0 9.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP04605.1 - 2.8e-05 23.3 0.0 5.1e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KFP04605.1 - 0.00015 21.0 0.1 0.00053 19.2 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 KFP04605.1 - 0.00083 18.5 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFP04605.1 - 0.0019 18.2 0.1 0.0051 16.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KFP04605.1 - 0.0044 16.5 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain IIGP PF05049.8 KFP04605.1 - 0.0076 15.1 0.0 0.015 14.1 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 KFP04605.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KFP04605.1 - 0.019 14.4 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFP04605.1 - 0.023 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Septin PF00735.13 KFP04605.1 - 0.032 13.2 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Septin DUF87 PF01935.12 KFP04605.1 - 0.037 13.8 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_5 PF07728.9 KFP04605.1 - 0.04 13.6 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KFP04605.1 - 0.057 12.3 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KFP04605.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KFP04605.1 - 0.092 12.9 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 KFP04605.1 - 0.15 12.2 0.1 0.73 9.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain TFIIE_alpha PF02002.12 KFP04606.1 - 2.3e-34 117.0 0.6 3.9e-34 116.3 0.4 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 KFP04606.1 - 5.9e-33 112.6 4.5 1.5e-32 111.4 3.1 1.7 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 KFP04606.1 - 1.1e-11 43.8 0.9 2.1e-11 42.9 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-Sec23_Sec24 PF04810.10 KFP04606.1 - 0.017 14.6 0.5 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger IFT43 PF15305.1 KFP04606.1 - 0.065 13.2 1.1 0.16 11.9 0.8 1.6 1 0 0 1 1 1 0 Intraflagellar transport protein 43 LLGL PF08366.8 KFP04607.1 - 3.6e-42 142.5 0.3 1.3e-41 140.7 0.0 2.0 2 0 0 2 2 2 1 LLGL2 WD40 PF00400.27 KFP04607.1 - 7e-12 44.7 0.5 0.046 13.6 0.0 6.2 5 1 0 5 5 5 2 WD domain, G-beta repeat Lgl_C PF08596.5 KFP04607.1 - 5.7e-06 25.0 0.1 0.00012 20.6 0.0 3.0 4 1 0 4 4 4 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.16 KFP04607.1 - 0.00075 19.0 0.1 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin DUF3312 PF11768.3 KFP04607.1 - 0.044 12.0 0.0 0.1 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Death PF00531.17 KFP04608.1 - 5.6e-17 61.2 0.5 8.6e-17 60.6 0.4 1.3 1 0 0 1 1 1 1 Death domain TNFR_c6 PF00020.13 KFP04608.1 - 1.3e-14 53.9 53.2 8.1e-08 32.1 5.8 4.9 4 1 0 4 4 4 3 TNFR/NGFR cysteine-rich region CTC1 PF15489.1 KFP04609.1 - 1.4e-35 122.1 0.1 1.5e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 Ig_3 PF13927.1 KFP04610.1 - 1.5e-09 38.2 2.8 9.9e-05 22.7 0.6 2.7 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP04610.1 - 3.9e-08 33.1 0.1 6.8e-07 29.1 0.0 2.6 1 1 1 2 2 2 1 Immunoglobulin V-set domain I-set PF07679.11 KFP04610.1 - 2.9e-07 30.2 3.4 0.0006 19.6 0.0 3.8 2 2 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP04610.1 - 1.2e-06 28.5 1.0 0.0042 17.1 0.0 2.5 1 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP04610.1 - 0.00014 21.9 1.9 0.0087 16.1 0.0 3.2 2 1 0 2 2 2 1 Immunoglobulin domain Receptor_2B4 PF11465.3 KFP04610.1 - 0.056 13.3 0.0 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 EpuA PF11772.3 KFP04610.1 - 0.12 11.7 3.1 0.24 10.8 2.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Filamin PF00630.14 KFP04611.1 - 5e-21 75.1 0.2 8.6e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-B_box PF00643.19 KFP04611.1 - 1.3e-08 34.5 12.1 1.3e-08 34.5 8.4 3.5 4 0 0 4 4 4 1 B-box zinc finger Laminin_II PF06009.7 KFP04611.1 - 0.028 14.1 0.5 0.047 13.4 0.4 1.3 1 0 0 1 1 1 0 Laminin Domain II Y_Y_Y PF07495.8 KFP04611.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Y_Y_Y domain KIAA1328 PF15369.1 KFP04611.1 - 0.43 10.3 6.5 0.65 9.7 4.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 TIG PF01833.19 KFP04613.1 - 7.3e-13 48.3 0.2 7.3e-13 48.3 0.2 2.8 2 0 0 2 2 2 1 IPT/TIG domain HLH PF00010.21 KFP04613.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain TRC8_N PF13705.1 KFP04614.1 - 1.9e-159 531.5 37.2 2.2e-159 531.2 25.8 1.0 1 0 0 1 1 1 1 TRC8 N-terminal domain zf-RING_2 PF13639.1 KFP04614.1 - 1.1e-11 44.3 7.6 1.1e-11 44.3 5.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP04614.1 - 4.2e-08 33.0 6.5 4.2e-08 33.0 4.5 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP04614.1 - 1.5e-07 31.4 7.6 4.7e-07 29.8 5.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFP04614.1 - 2.4e-06 27.1 8.4 2.4e-06 27.1 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP04614.1 - 3.5e-06 26.5 6.5 3.5e-06 26.5 4.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP04614.1 - 0.00033 20.3 10.1 0.00033 20.3 7.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFP04614.1 - 0.012 15.3 7.0 0.031 14.0 4.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KFP04614.1 - 0.088 12.3 6.5 0.21 11.1 4.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NHase_alpha PF02979.11 KFP04614.1 - 0.33 10.1 1.5 0.33 10.1 0.1 1.6 2 0 0 2 2 2 0 Nitrile hydratase, alpha chain zf-RING_UBOX PF13445.1 KFP04614.1 - 0.96 9.2 10.7 0.029 14.0 1.9 2.7 3 1 1 4 4 4 0 RING-type zinc-finger zf-P11 PF03854.9 KFP04614.1 - 7.3 6.1 13.9 0.67 9.4 5.4 2.4 2 0 0 2 2 2 0 P-11 zinc finger NIF PF03031.13 KFP04615.1 - 3.1e-29 101.6 0.2 5e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 KFP04615.1 - 1.6e-06 27.3 0.1 3.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KFP04615.1 - 0.014 15.6 0.1 0.037 14.2 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain Med22 PF06179.7 KFP04615.1 - 0.2 11.7 1.2 8.2 6.5 0.2 2.4 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex Kazal_1 PF00050.16 KFP04616.1 - 1.4e-17 63.3 4.6 1.6e-17 63.2 3.2 1.0 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFP04616.1 - 3.5e-14 52.4 2.6 4.5e-14 52.0 1.8 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain zinc_ribbon_2 PF13240.1 KFP04616.1 - 0.2 11.1 2.4 5.6 6.5 1.7 2.5 2 1 0 2 2 2 0 zinc-ribbon domain Kazal_1 PF00050.16 KFP04617.1 - 3.6e-51 170.9 31.3 5.7e-18 64.6 2.4 3.1 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFP04617.1 - 3.2e-32 110.1 30.4 6.7e-12 45.1 4.1 3.5 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain DUF393 PF04134.7 KFP04617.1 - 4.8 8.3 10.1 45 5.1 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function, DUF393 Kazal_1 PF00050.16 KFP04618.1 - 6.3e-105 343.0 65.2 1.4e-18 66.6 3.7 6.1 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFP04618.1 - 8.3e-67 220.8 55.7 6.1e-12 45.2 2.2 6.2 6 0 0 6 6 6 6 Kazal-type serine protease inhibitor domain FmdE PF02663.9 KFP04618.1 - 1.1 9.2 5.1 1.1 9.1 0.1 3.0 3 0 0 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Kazal_1 PF00050.16 KFP04619.1 - 4.1e-11 42.7 1.9 4.2e-11 42.6 1.4 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KFP04619.1 - 1.1e-08 34.7 0.8 1.3e-08 34.5 0.6 1.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.16 KFP04620.1 - 9.4e-71 237.9 19.9 1.2e-70 237.6 13.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04620.1 - 1.1e-12 47.7 15.7 1.4e-12 47.3 10.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP04620.1 - 0.00087 18.4 16.7 0.0019 17.3 11.6 1.6 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx T_cell_tran_alt PF15128.1 KFP04620.1 - 0.16 11.4 2.0 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Synaphin PF05835.7 KFP04621.1 - 8.7e-45 152.2 18.8 9.6e-45 152.1 13.0 1.0 1 0 0 1 1 1 1 Synaphin protein FCP1_C PF09309.5 KFP04621.1 - 0.23 10.7 10.7 0.28 10.4 7.4 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DDRGK PF09756.4 KFP04621.1 - 0.47 9.8 17.6 0.62 9.4 12.2 1.2 1 0 0 1 1 1 0 DDRGK domain TEX19 PF15553.1 KFP04621.1 - 1.1 9.0 5.4 1.4 8.7 3.7 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 BSP_II PF05432.6 KFP04621.1 - 2.4 7.3 13.8 2.9 7.0 9.6 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2570 PF10828.3 KFP04621.1 - 2.4 7.7 8.1 3.3 7.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Borrelia_P83 PF05262.6 KFP04621.1 - 2.4 6.3 14.1 2.6 6.2 9.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein VIT1 PF01988.14 KFP04621.1 - 3.4 7.1 5.9 4.3 6.7 4.1 1.3 1 0 0 1 1 1 0 VIT family DUF4407 PF14362.1 KFP04621.1 - 4.5 6.1 10.5 5.7 5.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 KFP04621.1 - 4.9 6.0 12.2 6.2 5.7 8.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CAF-1_p150 PF11600.3 KFP04621.1 - 5.6 6.2 27.9 8 5.7 19.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 KFP04621.1 - 7.3 4.5 9.7 8.8 4.2 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 KFP04621.1 - 8.6 3.9 9.2 8.5 3.9 6.4 1.0 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 KFP04621.1 - 8.6 5.9 7.9 11 5.6 5.5 1.3 1 0 0 1 1 1 0 IncA protein NODP PF07684.7 KFP04622.1 - 0.038 13.6 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein 6PF2K PF01591.13 KFP04622.1 - 0.12 11.4 0.1 0.26 10.3 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase P33MONOX PF15302.1 KFP04623.1 - 1.2e-148 494.5 10.3 1.3e-148 494.3 7.2 1.0 1 0 0 1 1 1 1 P33 mono-oxygenase DUF865 PF05906.6 KFP04623.1 - 0.15 11.6 2.5 0.2 11.2 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Nop16 PF09420.5 KFP04624.1 - 8.9e-32 110.4 1.8 1e-31 110.2 1.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ORF6C PF10552.4 KFP04624.1 - 0.0026 17.4 0.8 0.0036 17.0 0.6 1.3 1 0 0 1 1 1 1 ORF6C domain Myb_DNA-bind_4 PF13837.1 KFP04624.1 - 0.29 11.2 1.6 0.37 10.9 0.5 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain HIG_1_N PF04588.8 KFP04625.1 - 4.9e-26 90.2 0.7 6.1e-26 89.9 0.5 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Clathrin_lg_ch PF01086.12 KFP04626.1 - 9.2e-49 166.3 5.9 1.1e-48 166.0 4.1 1.0 1 0 0 1 1 1 1 Clathrin light chain Peptidase_M9_N PF08453.5 KFP04626.1 - 0.007 15.7 0.1 0.46 9.7 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M9 N-terminal NUFIP1 PF10453.4 KFP04626.1 - 2.3 7.7 9.2 0.11 12.0 2.1 1.9 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) UBA_4 PF14555.1 KFP04627.1 - 7.8e-08 31.7 0.3 4.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 KFP04627.1 - 1.1e-06 28.6 0.1 3.6e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 KFP04627.1 - 0.00067 19.4 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain NARP1 PF12569.3 KFP04627.1 - 0.035 12.8 10.2 0.054 12.2 7.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_23 PF13476.1 KFP04627.1 - 0.41 10.9 8.1 0.75 10.0 5.6 1.4 1 0 0 1 1 1 0 AAA domain DUF1682 PF07946.9 KFP04627.1 - 0.99 8.1 21.8 1.5 7.6 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1510 PF07423.6 KFP04627.1 - 1.2 8.4 11.1 1.9 7.8 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Selenoprotein_S PF06936.6 KFP04627.1 - 1.4 8.4 9.8 2.2 7.7 6.8 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Caldesmon PF02029.10 KFP04627.1 - 2.6 6.3 22.2 3.5 5.9 15.4 1.1 1 0 0 1 1 1 0 Caldesmon Cadherin PF00028.12 KFP04628.1 - 1.3e-97 320.2 16.7 1.8e-16 60.1 0.2 9.7 9 0 0 9 9 9 9 Cadherin domain Cadherin_2 PF08266.7 KFP04628.1 - 1e-09 37.8 0.0 0.59 9.7 0.0 5.3 5 0 0 5 5 5 4 Cadherin-like DUF2208 PF09973.4 KFP04628.1 - 0.011 14.9 0.4 0.02 14.1 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Herpes_LMP2 PF07415.6 KFP04628.1 - 0.022 13.3 0.5 0.036 12.6 0.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Adeno_E3_CR2 PF02439.10 KFP04628.1 - 5.2 6.7 6.8 16 5.1 4.7 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Synuclein PF01387.12 KFP04630.1 - 8.6e-20 70.9 5.1 1.4e-19 70.2 3.5 1.3 1 1 0 1 1 1 1 Synuclein IF4E PF01652.13 KFP04631.1 - 2e-57 193.2 0.9 2.4e-57 193.0 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ZU5 PF00791.15 KFP04632.1 - 1.2e-33 114.8 0.0 2.2e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain I-set PF07679.11 KFP04632.1 - 8.2e-12 44.8 0.0 2.1e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Death PF00531.17 KFP04632.1 - 1.6e-11 43.7 0.0 3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Death domain Ig_2 PF13895.1 KFP04632.1 - 4.9e-09 36.1 0.2 1.7e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain TSP_1 PF00090.14 KFP04632.1 - 4.9e-09 36.1 37.5 1.5e-07 31.3 9.5 2.8 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ig_3 PF13927.1 KFP04632.1 - 0.00027 21.3 0.0 0.0024 18.3 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP04632.1 - 0.035 13.9 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin V-set domain Hexokinase_2 PF03727.11 KFP04633.1 - 1.9e-178 590.4 3.3 6.6e-99 330.0 0.5 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFP04633.1 - 1.2e-137 455.8 0.0 1.2e-75 253.3 0.0 2.3 2 0 0 2 2 2 2 Hexokinase UIM PF02809.15 KFP04634.1 - 0.016 14.7 10.2 0.026 14.0 1.2 3.1 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-met PF12874.2 KFP04635.1 - 6.5e-14 51.5 16.3 1.3e-07 31.5 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP04635.1 - 1.9e-08 34.1 9.8 0.00029 20.8 1.2 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP04635.1 - 0.0017 18.4 8.4 0.12 12.4 0.6 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFP04635.1 - 0.0063 16.0 9.7 0.11 12.0 1.0 3.2 3 0 0 3 3 3 2 U1 zinc finger zf-C3HC4_2 PF13923.1 KFP04635.1 - 0.0078 16.2 0.2 2.3 8.2 0.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 KFP04635.1 - 0.023 14.8 1.4 2.6 8.2 0.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_4 PF13894.1 KFP04635.1 - 0.027 14.7 10.5 0.088 13.1 0.5 2.8 3 0 0 3 3 2 0 C2H2-type zinc finger DUF2946 PF11162.3 KFP04635.1 - 0.11 12.6 4.8 0.53 10.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) HoxA13_N PF12284.3 KFP04635.1 - 0.15 12.2 2.6 0.66 10.1 0.1 2.3 1 1 1 2 2 2 0 Hox protein A13 N terminal DUF2225 PF09986.4 KFP04635.1 - 0.3 10.4 2.1 0.89 8.9 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2256 PF10013.4 KFP04635.1 - 0.33 10.7 3.0 13 5.6 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_6 PF13912.1 KFP04635.1 - 0.41 10.6 8.3 3.3 7.7 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP04635.1 - 0.71 10.2 0.1 0.71 10.2 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04635.1 - 0.89 10.0 10.3 0.5 10.8 0.6 3.1 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-RING_3 PF14369.1 KFP04635.1 - 1.7 8.6 4.5 12 5.9 0.6 2.3 2 0 0 2 2 2 0 zinc-finger Pkinase_Tyr PF07714.12 KFP04636.1 - 3.5e-103 344.1 0.0 4.7e-103 343.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP04636.1 - 3.1e-47 160.9 0.0 4.5e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFP04636.1 - 1.4e-27 95.3 0.0 3.3e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP04636.1 - 4e-19 68.5 0.0 1.4e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP04636.1 - 1.2e-14 54.5 0.1 1.4e-07 31.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP04636.1 - 1.6e-13 50.5 0.2 3.1e-06 27.1 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP04636.1 - 6.7e-10 38.8 0.1 0.0043 16.9 0.0 3.4 2 2 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP04636.1 - 0.03 14.2 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.1 KFP04636.1 - 0.089 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SET PF00856.23 KFP04638.1 - 3.4e-25 89.2 3.1 6.7e-25 88.2 0.7 2.5 2 1 0 2 2 2 1 SET domain PHD PF00628.24 KFP04638.1 - 5.9e-19 67.5 69.9 1.1e-07 31.4 7.6 6.8 4 2 2 6 6 6 4 PHD-finger PWWP PF00855.12 KFP04638.1 - 1.1e-16 60.8 0.5 3e-16 59.3 0.3 1.8 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.1 KFP04638.1 - 2.5e-07 29.9 37.9 0.00056 19.1 1.4 6.1 5 1 0 5 5 5 4 PHD-finger Ras PF00071.17 KFP04639.1 - 2.9e-14 52.7 0.1 4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP04639.1 - 0.0082 16.6 0.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein PRELI PF04707.9 KFP04640.1 - 5.7e-39 133.1 0.1 8.1e-39 132.6 0.1 1.2 1 0 0 1 1 1 1 PRELI-like family Hs1pro-1_C PF07014.7 KFP04642.1 - 0.089 12.0 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus NARP1 PF12569.3 KFP04643.1 - 0.064 11.9 5.6 0.099 11.3 3.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DEAD PF00270.24 KFP04644.1 - 3.7e-42 143.6 0.0 3.2e-40 137.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP04644.1 - 1.1e-28 98.8 0.0 9e-28 95.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KFP04644.1 - 0.0032 17.4 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain zf-CCHC PF00098.18 KFP04644.1 - 0.0078 16.0 2.0 0.015 15.2 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF1253 PF06862.7 KFP04644.1 - 0.017 13.5 0.0 0.13 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) SecA_DEAD PF07517.9 KFP04644.1 - 0.017 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Helicase_C_4 PF13871.1 KFP04644.1 - 0.037 13.4 0.0 0.089 12.2 0.0 1.6 1 0 0 1 1 1 0 Helicase_C-like zf-CCHC_4 PF14392.1 KFP04644.1 - 0.21 11.2 1.3 0.46 10.1 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3886 PF13025.1 KFP04644.1 - 4.5 7.3 15.2 11 6.0 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) IRS PF02174.12 KFP04645.1 - 4.6e-30 103.1 0.0 8.1e-30 102.3 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) LIM PF00412.17 KFP04646.1 - 2.3e-41 139.6 33.7 2.7e-15 56.1 4.5 3.3 3 0 0 3 3 3 3 LIM domain PDZ PF00595.19 KFP04646.1 - 5.7e-13 48.8 0.0 9.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP04646.1 - 0.00098 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.20 KFP04647.1 - 5.2e-63 212.6 0.0 8.7e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04647.1 - 2.5e-35 121.7 0.0 3.6e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFP04647.1 - 5.7e-20 71.5 0.4 2.1e-19 69.7 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.1 KFP04647.1 - 0.00015 20.8 0.0 0.00025 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like 7tm_1 PF00001.16 KFP04648.1 - 5.4e-71 238.7 11.4 6.3e-71 238.5 7.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04648.1 - 8.1e-07 28.4 4.8 0.0074 15.4 0.4 2.4 2 1 1 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srsx Dr_adhesin PF12393.3 KFP04648.1 - 0.027 14.5 0.5 0.1 12.7 0.4 2.1 1 0 0 1 1 1 0 Dr family adhesin Na_Pi_cotrans PF02690.10 KFP04649.1 - 1.6e-59 199.7 27.4 3.4e-32 111.1 5.4 3.0 2 1 1 3 3 3 2 Na+/Pi-cotransporter RBD PF02196.10 KFP04650.1 - 1.6e-32 111.0 0.2 7.7e-23 80.0 0.0 2.3 2 0 0 2 2 2 2 Raf-like Ras-binding domain RGS PF00615.14 KFP04650.1 - 9.9e-28 96.6 2.4 2e-27 95.6 1.7 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain GoLoco PF02188.12 KFP04650.1 - 0.0024 17.1 1.3 0.006 15.8 0.9 1.7 1 0 0 1 1 1 1 GoLoco motif Arf PF00025.16 KFP04651.1 - 1.7e-67 226.0 0.0 1.8e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFP04651.1 - 1.2e-12 47.4 0.0 1.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFP04651.1 - 1.4e-12 47.3 0.0 1.6e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP04651.1 - 1.6e-11 44.7 0.0 2.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFP04651.1 - 1e-09 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP04651.1 - 4.9e-09 36.1 0.0 6.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFP04651.1 - 2e-08 33.3 0.2 4.2e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 KFP04651.1 - 3.2e-07 29.9 0.0 0.00013 21.4 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KFP04651.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KFP04651.1 - 0.021 15.1 0.2 0.037 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFP04651.1 - 0.022 14.6 0.1 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFP04651.1 - 0.037 13.4 0.0 3 7.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KFP04651.1 - 0.043 13.7 0.0 0.084 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KFP04651.1 - 0.047 12.9 0.1 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_17 PF13207.1 KFP04651.1 - 0.065 14.0 0.1 0.12 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFP04651.1 - 0.08 13.2 0.1 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KFP04651.1 - 0.084 13.0 0.1 0.31 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KFP04651.1 - 0.087 12.5 0.1 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KFP04651.1 - 0.096 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Lectin_leg-like PF03388.8 KFP04652.1 - 2.9e-89 298.1 0.0 3.4e-89 297.9 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KFP04652.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.4 1 1 0 1 1 1 0 Legume lectin domain Glyco_transf_7C PF02709.9 KFP04653.1 - 3.9e-27 93.5 0.2 7.9e-27 92.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 KFP04653.1 - 1e-23 83.2 0.1 1.5e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 KFP04653.1 - 1.3e-05 24.4 0.0 0.01 14.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Ribosomal_L7Ae PF01248.21 KFP04654.1 - 2.3e-21 75.1 0.0 2.6e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Kinesin PF00225.18 KFP04655.1 - 3.2e-101 338.3 0.5 3.2e-101 338.3 0.3 1.7 2 0 0 2 2 2 1 Kinesin motor domain Mtc PF03820.12 KFP04656.1 - 8.3e-148 491.0 0.0 1e-147 490.7 0.0 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier 7tm_1 PF00001.16 KFP04657.1 - 1.3e-79 266.9 18.7 1.6e-79 266.6 13.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04657.1 - 1.8e-09 37.1 17.1 3e-09 36.4 11.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP04657.1 - 1.8e-06 27.2 14.3 1.8e-06 27.2 9.9 2.4 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Homeobox PF00046.24 KFP04658.1 - 1e-22 79.4 5.2 1.5e-22 78.9 3.6 1.2 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP04658.1 - 0.16 11.0 0.8 0.48 9.5 0.1 1.9 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Calcyon PF06387.6 KFP04659.1 - 2.3e-89 297.7 0.1 2.6e-89 297.5 0.0 1.0 1 0 0 1 1 1 1 D1 dopamine receptor-interacting protein (calcyon) COMPASS-Shg1 PF05205.7 KFP04660.1 - 1.2e-20 73.7 0.0 1.4e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Stanniocalcin PF03298.8 KFP04661.1 - 2.5e-83 278.2 12.8 2.9e-83 277.9 8.9 1.0 1 0 0 1 1 1 1 Stanniocalcin family Homeobox PF00046.24 KFP04662.1 - 9e-21 73.2 4.2 9e-21 73.2 2.9 1.7 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 KFP04662.1 - 0.083 11.9 0.3 0.18 10.8 0.2 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sec20 PF03908.8 KFP04663.1 - 2.5e-33 113.6 3.3 2.5e-33 113.6 2.3 2.2 2 0 0 2 2 2 1 Sec20 DUF2777 PF10949.3 KFP04663.1 - 0.0024 17.6 2.2 0.003 17.2 1.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2777) WD-3 PF09765.4 KFP04663.1 - 0.11 11.7 3.8 0.14 11.3 2.6 1.1 1 0 0 1 1 1 0 WD-repeat region 7tm_6 PF02949.15 KFP04663.1 - 0.14 11.0 3.3 0.059 12.2 0.7 1.5 2 0 0 2 2 2 0 7tm Odorant receptor Tombus_P33 PF08500.5 KFP04663.1 - 0.33 10.6 2.4 0.32 10.7 0.2 1.8 2 0 0 2 2 2 0 Tombusvirus p33 Sec16 PF12932.2 KFP04663.1 - 0.37 10.7 2.5 0.65 9.9 0.1 2.3 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Cep57_MT_bd PF06657.8 KFP04663.1 - 0.57 10.1 10.4 0.12 12.3 1.4 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ThiG PF05690.9 KFP04663.1 - 0.91 8.5 3.8 6.4 5.7 0.8 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DUF4337 PF14235.1 KFP04663.1 - 1 9.1 16.0 3.6 7.4 3.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) DUF1664 PF07889.7 KFP04663.1 - 1.1 9.1 8.6 4.1 7.2 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 KFP04663.1 - 1.2 8.7 15.8 2.3 7.8 10.9 1.5 1 1 0 1 1 1 0 Mnd1 family ACCA PF03255.9 KFP04663.1 - 1.5 8.3 7.2 0.33 10.4 1.6 2.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Folliculin PF11704.3 KFP04663.1 - 1.6 8.2 10.7 0.38 10.3 1.1 2.1 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Syntaxin PF00804.20 KFP04663.1 - 3 8.0 17.0 0.24 11.5 2.4 2.3 1 1 1 2 2 2 0 Syntaxin DUF2924 PF11149.3 KFP04663.1 - 3 7.8 10.9 27 4.7 7.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) DUF572 PF04502.8 KFP04663.1 - 4.1 6.5 15.7 5 6.2 10.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF972 PF06156.8 KFP04663.1 - 5.1 7.4 16.7 1.1 9.6 2.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Syntaxin-6_N PF09177.6 KFP04663.1 - 5.1 7.5 11.7 12 6.3 2.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V-SNARE_C PF12352.3 KFP04663.1 - 6.8 6.8 10.8 1.2 9.2 3.7 2.4 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus CorA PF01544.13 KFP04663.1 - 7.1 5.5 11.0 1.8 7.5 5.6 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Elongin_A PF06881.6 KFP04663.1 - 8.3 6.8 10.4 3.9 7.9 5.4 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A bZIP_1 PF00170.16 KFP04664.1 - 0.00031 20.6 3.3 0.00031 20.6 2.3 3.0 3 0 0 3 3 3 1 bZIP transcription factor TFIIA PF03153.8 KFP04664.1 - 0.016 15.0 13.9 0.034 14.0 9.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_2 PF07716.10 KFP04664.1 - 0.018 14.8 2.3 0.018 14.8 1.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Nop14 PF04147.7 KFP04664.1 - 4.9 4.9 20.2 7.6 4.3 14.0 1.2 1 0 0 1 1 1 0 Nop14-like family KOW PF00467.24 KFP04665.1 - 4.3e-08 32.5 5.9 1.8e-07 30.6 4.1 2.2 1 1 0 1 1 1 1 KOW motif PilP PF04351.8 KFP04665.1 - 0.16 11.9 2.1 0.26 11.1 1.5 1.6 1 1 0 1 1 1 0 Pilus assembly protein, PilP Toxin_56 PF15534.1 KFP04665.1 - 0.49 10.9 5.7 0.21 12.0 0.6 2.2 2 1 0 2 2 2 0 Putative toxin 56 COPIIcoated_ERV PF07970.7 KFP04666.1 - 1.4e-37 129.5 0.2 2.3e-37 128.7 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFP04666.1 - 1.3e-24 85.9 1.1 2.6e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DSPc PF00782.15 KFP04667.1 - 3.5e-49 165.8 0.0 4.3e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFP04667.1 - 2.4e-07 30.3 0.0 2.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFP04667.1 - 0.002 18.1 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 KFP04667.1 - 0.081 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Neuralized PF07177.7 KFP04668.1 - 6.8e-41 137.9 0.3 1.3e-24 85.7 0.1 2.5 2 0 0 2 2 2 2 Neuralized zf-C3HC4_3 PF13920.1 KFP04668.1 - 6.4e-13 48.1 13.2 1.4e-12 47.0 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP04668.1 - 2e-05 24.4 15.9 5.1e-05 23.2 11.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP04668.1 - 0.024 14.3 15.0 0.059 13.1 10.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain SH3_1 PF00018.23 KFP04669.1 - 9.9e-39 130.5 13.5 6.7e-13 47.8 0.1 4.4 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.1 KFP04669.1 - 1.1e-34 117.7 8.6 9.4e-13 47.5 0.1 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.12 KFP04669.1 - 3.8e-31 106.3 6.1 3.8e-09 35.8 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 KFP04669.1 - 2.8e-13 49.8 13.5 0.00065 19.8 0.5 4.4 4 0 0 4 4 4 4 Bacterial SH3 domain PX PF00787.19 KFP04669.1 - 4.5e-07 29.6 2.0 1.9e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 PX domain SH3_4 PF06347.8 KFP04669.1 - 0.0021 17.5 0.9 0.0021 17.5 0.6 4.0 4 0 0 4 4 4 3 Bacterial SH3 domain ubiquitin PF00240.18 KFP04670.1 - 2.1e-13 49.4 0.0 3.1e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFP04670.1 - 1.6e-06 27.7 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Duffy_binding PF05424.6 KFP04670.1 - 0.088 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Duffy binding domain TPR_12 PF13424.1 KFP04671.1 - 1.6e-17 63.1 42.6 5.1e-06 26.3 2.0 8.6 6 2 4 10 10 10 8 Tetratricopeptide repeat SH3_9 PF14604.1 KFP04671.1 - 8.9e-14 50.8 0.1 1.1e-08 34.4 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 KFP04671.1 - 2.3e-11 43.0 0.1 3.1e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain TPR_11 PF13414.1 KFP04671.1 - 1.3e-09 37.5 36.6 0.024 14.2 2.9 7.2 6 1 0 6 6 6 6 TPR repeat SH3_1 PF00018.23 KFP04671.1 - 1.7e-08 33.7 0.2 0.00097 18.4 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SNAP PF14938.1 KFP04671.1 - 2.1e-06 27.0 3.5 6.7e-06 25.4 0.6 2.8 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.23 KFP04671.1 - 3.2e-05 23.3 31.0 0.0014 18.1 0.0 8.8 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP04671.1 - 0.03 14.2 0.1 0.03 14.2 0.0 10.9 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP04671.1 - 2.7 7.9 25.5 6 6.8 0.0 8.8 11 0 0 11 11 11 0 Tetratricopeptide repeat LIM PF00412.17 KFP04672.1 - 7.1e-42 141.2 49.2 1.9e-14 53.4 2.7 4.7 4 1 1 5 5 5 4 LIM domain VHP PF02209.14 KFP04672.1 - 1.5e-17 62.9 0.8 3.6e-17 61.7 0.6 1.7 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.24 KFP04673.1 - 1.7e-19 69.9 0.0 1.9e-08 34.4 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFP04673.1 - 0.00017 21.7 1.6 0.092 12.9 0.0 3.7 3 1 0 3 3 3 2 Pleckstrin homology domain Macoilin PF09726.4 KFP04673.1 - 0.00083 17.7 6.5 0.00083 17.7 4.5 1.6 2 0 0 2 2 2 1 Transmembrane protein PH_9 PF15410.1 KFP04673.1 - 0.13 12.3 1.9 23 5.1 0.0 3.6 3 2 0 3 3 3 0 Pleckstrin homology domain APG6 PF04111.7 KFP04673.1 - 3.3 6.6 11.9 7.1 5.5 8.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KFP04673.1 - 9.3 3.9 5.5 15 3.2 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.14 KFP04674.1 - 8e-43 145.8 0.0 9.6e-43 145.5 0.0 1.0 1 0 0 1 1 1 1 GrpE DUF2408 PF10303.4 KFP04674.1 - 0.044 13.9 0.4 0.061 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) AAA_27 PF13514.1 KFP04674.1 - 0.046 11.4 0.4 0.058 11.0 0.3 1.0 1 0 0 1 1 1 0 AAA domain Laminin_I PF06008.9 KFP04674.1 - 0.061 12.6 0.1 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Laminin Domain I Rad4 PF03835.10 KFP04674.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Prenylcys_lyase PF07156.9 KFP04675.1 - 5.3e-156 519.1 0.0 6.2e-156 518.9 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KFP04675.1 - 6.9e-08 32.4 0.2 2e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFP04675.1 - 0.003 17.3 0.1 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 KFP04675.1 - 0.029 13.3 0.1 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_zinc_N PF00107.21 KFP04675.1 - 0.093 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IL17 PF06083.6 KFP04676.1 - 2.9e-28 97.7 1.7 4.6e-28 97.0 1.2 1.3 1 0 0 1 1 1 1 Interleukin-17 Pkinase PF00069.20 KFP04677.1 - 3.4e-29 101.7 0.0 4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04677.1 - 1.7e-09 37.1 0.0 1.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFP04677.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KFP04677.1 - 0.041 12.8 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFP04677.1 - 0.11 12.2 0.2 0.43 10.2 0.1 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family zf-B_box PF00643.19 KFP04678.1 - 2.1e-09 37.0 27.4 2e-08 33.9 5.0 3.7 3 1 1 4 4 4 3 B-box zinc finger DUF2180 PF09947.4 KFP04678.1 - 0.63 9.8 7.2 0.8 9.5 0.6 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Papo_T_antigen PF02380.10 KFP04678.1 - 0.7 9.8 12.9 0.065 13.1 2.6 2.3 2 0 0 2 2 2 0 T-antigen specific domain zf-UBR PF02207.15 KFP04678.1 - 4.5 7.0 20.4 0.82 9.4 4.7 2.5 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.19 KFP04679.1 - 3.5e-05 23.5 8.2 3.5e-05 23.5 5.7 3.5 4 1 0 4 4 4 1 B-box zinc finger NRN1 PF15056.1 KFP04679.1 - 0.011 15.6 1.5 0.011 15.6 1.1 1.8 2 0 0 2 2 2 0 Neuritin protein family Prok-RING_2 PF14445.1 KFP04679.1 - 1.5 8.7 17.8 4.9 7.1 0.0 4.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 2 Sulfate_transp PF00916.15 KFP04680.1 - 3.2e-80 269.1 7.4 6.1e-80 268.2 5.2 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFP04680.1 - 5.8e-31 106.0 4.1 5.8e-31 106.0 2.8 3.3 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFP04680.1 - 2.2e-28 98.0 0.0 3.9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 KFP04681.1 - 2.6e-70 236.6 7.5 2.6e-70 236.6 5.2 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFP04681.1 - 1.1e-25 89.1 0.4 1.1e-25 89.1 0.3 4.0 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFP04681.1 - 5.4e-25 87.0 0.0 9.5e-25 86.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain PAP2 PF01569.16 KFP04681.1 - 0.068 12.8 6.0 0.11 12.1 0.0 3.9 4 2 0 4 4 4 0 PAP2 superfamily STAS_2 PF13466.1 KFP04681.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 STAS domain DUF543 PF04418.7 KFP04681.1 - 0.31 11.0 2.2 0.45 10.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) 7tm_1 PF00001.16 KFP04682.1 - 2.7e-74 249.5 13.9 3.6e-74 249.1 9.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KFP04682.1 - 0.76 9.3 14.6 2.1 7.8 10.1 1.8 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 F-box PF00646.28 KFP04683.1 - 9.8e-05 21.9 0.1 0.00029 20.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFP04683.1 - 0.00092 18.8 0.3 0.0023 17.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like IL12p40_C PF10420.4 KFP04684.1 - 2.8e-26 91.4 2.2 2.1e-25 88.6 0.7 2.6 3 0 0 3 3 3 1 Cytokine interleukin-12p40 C-terminus Ig_2 PF13895.1 KFP04684.1 - 0.0011 18.9 1.9 0.0037 17.3 0.6 2.4 1 1 1 2 2 2 1 Immunoglobulin domain SH2 PF00017.19 KFP04684.1 - 0.0037 17.0 0.0 0.048 13.4 0.0 2.6 2 1 0 2 2 2 1 SH2 domain Ig_3 PF13927.1 KFP04684.1 - 0.0037 17.7 0.4 0.0037 17.7 0.3 3.6 3 1 1 4 4 4 1 Immunoglobulin domain GPI-anchored PF10342.4 KFP04684.1 - 0.012 16.1 1.9 9.6 6.7 0.0 3.3 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ig PF00047.20 KFP04684.1 - 0.021 14.9 1.0 0.021 14.9 0.7 3.2 3 2 1 4 4 4 0 Immunoglobulin domain V-set PF07686.12 KFP04684.1 - 0.046 13.6 0.3 0.046 13.6 0.2 3.0 3 1 1 4 4 4 0 Immunoglobulin V-set domain I-set PF07679.11 KFP04684.1 - 0.067 13.0 2.2 3.2 7.6 0.1 3.9 3 2 2 5 5 5 0 Immunoglobulin I-set domain Neur_chan_memb PF02932.11 KFP04685.1 - 2.2e-50 171.7 3.7 6.2e-45 153.9 0.3 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP04685.1 - 6.8e-41 139.8 1.9 9.4e-41 139.3 1.3 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 KFP04686.1 - 1.1e-52 178.3 0.0 1.4e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP04686.1 - 4.1e-45 154.5 6.1 1.4e-36 126.6 4.1 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP04687.1 - 2.4e-52 177.2 0.0 3.2e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP04687.1 - 2.8e-48 164.8 5.4 3.6e-42 144.8 2.3 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Mito_fiss_reg PF05308.6 KFP04687.1 - 0.01 15.2 6.0 0.016 14.6 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Cyclin_N PF00134.18 KFP04687.1 - 0.012 15.2 0.4 0.021 14.3 0.3 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF4396 PF14342.1 KFP04687.1 - 0.72 9.9 8.6 4.5 7.3 6.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4396) Neur_chan_memb PF02932.11 KFP04688.1 - 5e-54 183.7 1.5 2.4e-53 181.4 1.1 1.9 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP04688.1 - 1.1e-52 178.3 0.0 2.3e-52 177.3 0.0 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain E1-E2_ATPase PF00122.15 KFP04689.1 - 5.4e-15 55.0 1.0 1.1e-14 54.0 0.0 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KFP04689.1 - 1.4e-14 55.0 0.1 6.2e-10 39.8 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFP04689.1 - 9.1e-14 52.0 0.3 1.6e-12 47.9 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP04689.1 - 1.6e-08 34.3 0.0 6.3e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFP04689.1 - 0.0077 15.8 2.3 0.012 15.2 0.3 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Securin PF04856.8 KFP04690.1 - 1.8e-16 60.5 0.2 2.1e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor Slu7 PF11708.3 KFP04691.1 - 1.6e-87 293.2 12.2 1.6e-87 293.2 8.5 2.8 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KFP04691.1 - 0.019 14.6 0.2 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle FmdE PF02663.9 KFP04691.1 - 1.7 8.5 5.1 3.2 7.6 2.1 2.5 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon C1q PF00386.16 KFP04692.1 - 3.6e-38 130.4 0.0 4.4e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP04692.1 - 1e-17 63.3 62.0 7.9e-10 38.1 23.9 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Cyclin_C PF02984.14 KFP04693.1 - 3.3e-26 91.5 2.3 5e-22 78.0 0.1 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 KFP04693.1 - 8.1e-18 64.2 1.2 1.7e-17 63.1 0.8 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 KFP04693.1 - 0.17 11.7 0.1 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Lipocalin_7 PF14651.1 KFP04694.1 - 5.5e-61 203.9 1.6 6.1e-61 203.7 1.1 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF4166 PF13761.1 KFP04694.1 - 0.0045 16.8 0.0 0.0052 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4166) DUF3047 PF11249.3 KFP04694.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) PWWP PF00855.12 KFP04695.1 - 2.1e-12 47.0 0.0 2.1e-12 47.0 0.0 2.9 2 1 0 2 2 2 1 PWWP domain DUF1018 PF06252.7 KFP04695.1 - 1.5 9.3 11.2 4.4 7.8 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1018) TPR_11 PF13414.1 KFP04696.1 - 5.2e-25 86.8 2.3 8.5e-19 66.9 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFP04696.1 - 9.3e-24 82.0 0.7 3.1e-07 29.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP04696.1 - 1.7e-18 64.9 0.9 1.9e-05 24.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFP04696.1 - 6.7e-10 38.0 2.0 0.01 15.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP04696.1 - 8.4e-10 38.4 0.9 8.1e-05 22.4 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP04696.1 - 8.2e-09 35.9 0.2 2.1e-05 25.0 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP04696.1 - 2.8e-07 30.7 3.8 5.6e-05 23.4 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 KFP04696.1 - 1.1e-06 27.9 1.8 0.0051 15.9 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP04696.1 - 7.9e-06 25.6 1.8 4.5e-05 23.2 0.6 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFP04696.1 - 1.1e-05 25.5 0.4 0.18 12.5 0.1 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP04696.1 - 1.3e-05 25.0 2.2 0.0015 18.5 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP04696.1 - 5.3e-05 22.7 0.5 0.25 11.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP04696.1 - 0.00025 21.3 1.5 0.013 15.9 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat A2M_N PF01835.14 KFP04696.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 MG2 domain PGP_phosphatase PF09419.5 KFP04696.1 - 0.13 11.5 0.2 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Fis1_TPR_C PF14853.1 KFP04696.1 - 0.2 11.5 1.7 5.8 6.8 0.1 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.4 KFP04696.1 - 0.27 10.5 8.8 0.13 11.5 0.9 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 7tm_1 PF00001.16 KFP04697.1 - 3e-84 282.1 7.8 4.2e-84 281.7 5.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04697.1 - 2.3e-16 59.7 3.7 5.6e-16 58.4 2.6 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP04697.1 - 0.00029 20.0 8.2 0.00029 20.0 5.7 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DOCK-C2 PF14429.1 KFP04699.1 - 8.9e-49 165.6 0.0 3e-48 163.8 0.0 2.0 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KFP04699.1 - 7.4e-42 142.6 0.1 3.3e-41 140.5 0.0 2.2 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KFP04699.1 - 1.1e-05 24.7 0.0 2.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP04699.1 - 1.2e-05 24.7 0.0 2.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP04699.1 - 0.00031 20.1 0.0 0.00068 19.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAM196 PF15265.1 KFP04700.1 - 5.6e-159 530.6 22.2 6.3e-159 530.5 15.4 1.0 1 0 0 1 1 1 1 FAM196 family Tropomyosin PF00261.15 KFP04700.1 - 0.098 11.7 1.4 0.34 9.9 0.7 1.8 2 0 0 2 2 2 0 Tropomyosin Fork_head PF00250.13 KFP04701.1 - 8.9e-44 147.4 0.1 1.1e-43 147.2 0.1 1.0 1 0 0 1 1 1 1 Fork head domain SH2 PF00017.19 KFP04702.1 - 1.7e-13 50.1 0.0 3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SAM_2 PF07647.12 KFP04702.1 - 1.6e-10 40.6 0.0 2.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP04702.1 - 0.0055 16.8 0.0 0.0095 16.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NOA36 PF06524.7 KFP04702.1 - 6.3 5.9 5.4 8.8 5.4 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein CaKB PF03185.10 KFP04703.1 - 1.8e-80 269.1 0.7 2e-80 268.9 0.5 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit EF-hand_7 PF13499.1 KFP04704.1 - 4.5e-25 87.5 3.3 5.3e-15 55.3 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP04704.1 - 9e-19 65.2 5.9 3.4e-07 29.0 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KFP04704.1 - 1.2e-16 60.0 1.8 4e-05 23.1 0.0 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFP04704.1 - 1.6e-16 58.5 2.9 0.00019 21.0 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KFP04704.1 - 8.1e-12 43.9 3.9 4.9e-05 22.4 0.0 3.5 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 KFP04704.1 - 1.3e-06 28.4 0.4 2.6e-05 24.1 0.1 2.7 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFP04704.1 - 0.0014 18.3 1.7 0.061 13.0 0.1 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFP04704.1 - 0.0041 17.0 0.2 6.8 6.6 0.0 3.8 3 1 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 KFP04704.1 - 0.017 14.7 0.5 5.4 6.7 0.0 3.0 3 0 0 3 3 3 0 EF hand EF-hand_2 PF09068.6 KFP04704.1 - 0.017 15.1 0.1 1.6 8.8 0.0 2.6 2 1 0 2 2 2 0 EF hand S10_plectin PF03501.10 KFP04704.1 - 0.025 14.4 0.1 0.056 13.3 0.1 1.6 1 1 0 1 1 1 0 Plectin/S10 domain DUF4176 PF13780.1 KFP04704.1 - 0.11 12.1 0.8 18 5.1 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4176) Neur_chan_LBD PF02931.18 KFP04705.1 - 1.1e-47 162.0 0.6 1.6e-47 161.4 0.0 1.5 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP04705.1 - 7.4e-30 104.5 11.5 3.1e-26 92.7 3.9 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region I-set PF07679.11 KFP04706.1 - 1.2e-14 53.9 0.0 1.8e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Kazal_1 PF00050.16 KFP04706.1 - 5.8e-06 26.2 6.3 5.8e-06 26.2 4.4 2.7 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Ig_2 PF13895.1 KFP04706.1 - 7.4e-06 25.9 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP04706.1 - 2.2e-05 24.5 0.3 7.2e-05 22.8 0.0 2.1 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP04706.1 - 0.0007 19.4 0.0 0.0017 18.2 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin V-set domain IGFBP PF00219.13 KFP04706.1 - 0.0014 19.1 20.5 0.0014 19.1 14.2 2.1 2 0 0 2 2 2 1 Insulin-like growth factor binding protein Nucleoplasmin PF03066.10 KFP04707.1 - 6.4e-47 158.7 24.5 1.8e-46 157.3 17.0 1.7 1 1 0 1 1 1 1 Nucleoplasmin TFIIF_alpha PF05793.7 KFP04707.1 - 0.00038 18.9 17.4 0.00042 18.8 12.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGT1 PF07093.6 KFP04707.1 - 0.0014 17.0 6.9 0.0015 17.0 4.8 1.2 1 0 0 1 1 1 1 SGT1 protein CENP-T PF15511.1 KFP04707.1 - 0.0031 16.8 11.6 0.0034 16.6 8.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Nop14 PF04147.7 KFP04707.1 - 0.019 12.8 24.5 0.027 12.4 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KFP04707.1 - 0.1 11.0 16.4 0.14 10.6 11.4 1.2 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 KFP04707.1 - 0.36 10.5 16.8 0.62 9.7 11.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 KFP04707.1 - 1.3 8.2 19.8 2.3 7.4 13.7 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KFP04707.1 - 1.6 6.6 11.7 2.1 6.2 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KFP04707.1 - 1.6 7.8 12.6 3.2 6.9 8.7 1.4 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.3 KFP04707.1 - 2.4 8.8 26.5 0.68 10.5 10.2 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal YL1 PF05764.8 KFP04707.1 - 7.9 6.0 28.8 20 4.7 20.0 1.6 1 1 0 1 1 1 0 YL1 nuclear protein FGF PF00167.13 KFP04708.1 - 1.9e-37 127.7 0.1 2.7e-37 127.2 0.1 1.2 1 0 0 1 1 1 1 Fibroblast growth factor WD40 PF00400.27 KFP04709.1 - 2.2e-60 198.5 17.0 5.1e-10 38.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.3 KFP04709.1 - 5.9e-28 96.1 2.3 1.1e-27 95.2 1.6 1.5 1 0 0 1 1 1 1 D domain of beta-TrCP F-box-like PF12937.2 KFP04709.1 - 1.5e-09 37.4 0.2 3.8e-09 36.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like Nucleoporin_N PF08801.6 KFP04709.1 - 1.1e-07 31.0 3.8 0.009 14.8 0.0 3.9 1 1 3 4 4 4 2 Nup133 N terminal like F-box PF00646.28 KFP04709.1 - 1.4e-07 31.0 0.0 4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KFP04709.1 - 0.00046 18.4 9.0 0.24 9.4 0.2 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF4508 PF14969.1 KFP04709.1 - 0.034 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) PQQ_3 PF13570.1 KFP04709.1 - 0.096 12.9 0.1 60 4.1 0.0 3.8 3 1 1 4 4 4 0 PQQ-like domain eRF1_2 PF03464.10 KFP04710.1 - 1.1e-45 155.2 0.1 1.7e-45 154.5 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KFP04710.1 - 3.6e-39 133.5 0.3 7.7e-39 132.4 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KFP04710.1 - 4e-23 81.4 0.0 7.2e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KFP04710.1 - 0.0044 16.5 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RmlD_sub_bind PF04321.12 KFP04711.1 - 7.3e-81 271.1 0.0 8.6e-81 270.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KFP04711.1 - 6.5e-23 81.3 0.0 8.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFP04711.1 - 1.2e-09 37.5 0.1 6.4e-07 28.5 0.1 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KFP04711.1 - 7.3e-08 31.6 0.0 4.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KFP04711.1 - 3.2e-07 30.5 0.0 4.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFP04711.1 - 0.00013 20.8 0.1 0.00042 19.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFP04711.1 - 0.011 15.6 0.9 0.092 12.6 0.1 2.7 2 2 0 2 2 2 0 short chain dehydrogenase Reo_sigmaC PF04582.7 KFP04712.1 - 0.21 10.7 34.0 0.045 12.9 2.5 4.4 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Cyclin_N PF00134.18 KFP04713.1 - 2.2e-21 75.7 0.2 4.5e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain tRNA-synt_1d PF00750.14 KFP04714.1 - 1.6e-135 451.5 0.0 2.1e-135 451.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.11 KFP04714.1 - 1.1e-20 73.9 0.0 4.4e-20 71.9 0.0 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain DALR_1 PF05746.10 KFP04714.1 - 1.1e-20 73.7 0.1 2.9e-20 72.3 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain CCDC14 PF15254.1 KFP04714.1 - 0.06 11.7 0.5 0.11 10.8 0.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 tRNA-synt_1 PF00133.17 KFP04714.1 - 0.11 10.5 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) WW PF00397.21 KFP04715.1 - 1.1e-08 34.7 0.2 2.6e-08 33.5 0.2 1.7 1 0 0 1 1 1 1 WW domain Sec2p PF06428.6 KFP04715.1 - 0.00089 19.0 1.6 0.00089 19.0 1.1 5.0 6 1 0 6 6 6 1 GDP/GTP exchange factor Sec2p Ten_N PF06484.7 KFP04717.1 - 1.6e-33 116.3 3.2 1.8e-33 116.1 2.2 1.0 1 0 0 1 1 1 1 Teneurin Intracellular Region Lipase_GDSL_2 PF13472.1 KFP04718.1 - 7.1e-05 23.0 0.0 0.00017 21.7 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Perilipin PF03036.11 KFP04720.1 - 4.5e-37 127.8 0.5 4.9e-37 127.7 0.4 1.0 1 0 0 1 1 1 1 Perilipin family Snf7 PF03357.16 KFP04721.1 - 3.1e-46 156.8 8.5 3.4e-46 156.7 5.9 1.0 1 0 0 1 1 1 1 Snf7 SYF2 PF08231.7 KFP04721.1 - 0.035 14.2 1.0 0.054 13.6 0.7 1.2 1 0 0 1 1 1 0 SYF2 splicing factor AAA_27 PF13514.1 KFP04721.1 - 0.047 11.3 5.6 0.053 11.2 3.9 1.0 1 0 0 1 1 1 0 AAA domain Enkurin PF13864.1 KFP04721.1 - 0.39 10.9 7.1 0.56 10.4 0.1 2.6 1 1 0 2 2 2 0 Calmodulin-binding CHASE3 PF05227.8 KFP04721.1 - 0.66 9.6 5.5 0.78 9.4 0.1 2.6 1 1 2 3 3 3 0 CHASE3 domain Cwf_Cwc_15 PF04889.7 KFP04721.1 - 1.4 8.5 5.5 1.7 8.3 3.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tropomodulin PF03250.9 KFP04721.1 - 3.7 7.0 9.7 0.26 10.7 1.4 2.4 1 1 2 3 3 3 0 Tropomodulin GreA_GreB_N PF03449.10 KFP04721.1 - 8.6 6.4 8.3 12 6.0 0.2 3.0 2 1 0 3 3 3 0 Transcription elongation factor, N-terminal zf-H2C2_2 PF13465.1 KFP04722.1 - 3.7e-36 121.6 93.5 1.3e-08 34.6 0.0 13.4 13 0 0 13 13 13 9 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04722.1 - 9.5e-32 107.4 113.6 0.00014 21.9 1.1 12.5 12 0 0 12 12 12 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04722.1 - 6.9e-29 98.0 102.5 0.0014 18.7 0.2 12.3 12 0 0 12 12 12 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP04722.1 - 4.1e-08 33.1 86.0 0.014 15.5 2.0 12.0 11 1 1 12 12 12 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP04722.1 - 5.2e-07 29.3 82.0 0.03 14.2 0.5 11.8 12 0 0 12 12 12 6 C2H2-type zinc finger BolA PF01722.13 KFP04722.1 - 1.1e-06 28.5 8.8 0.0015 18.4 0.1 4.2 3 2 1 4 4 4 2 BolA-like protein zf-C2H2_2 PF12756.2 KFP04722.1 - 0.00043 20.3 67.1 0.21 11.7 0.6 8.7 2 2 5 8 8 8 5 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 KFP04722.1 - 0.00097 18.6 9.7 1 9.0 0.3 3.8 3 0 0 3 3 3 3 GAGA factor zf-met PF12874.2 KFP04722.1 - 0.0024 18.0 75.7 0.9 9.8 0.9 11.7 12 0 0 12 12 12 6 Zinc-finger of C2H2 type PyrI_C PF02748.10 KFP04722.1 - 0.21 11.0 0.1 0.21 11.0 0.1 7.7 9 0 0 9 9 9 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain 4HBT_3 PF13622.1 KFP04722.1 - 0.24 11.1 9.9 0.064 12.9 4.4 1.8 2 0 0 2 2 2 0 Thioesterase-like superfamily zf-FPG_IleRS PF06827.9 KFP04722.1 - 6.7 6.4 11.7 0.36 10.5 0.8 3.8 3 0 0 3 3 2 0 Zinc finger found in FPG and IleRS Tim17 PF02466.14 KFP04723.1 - 1.3e-19 70.5 0.7 1.8e-19 70.0 0.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family EFP PF01132.15 KFP04723.1 - 0.24 11.1 0.9 0.5 10.0 0.5 1.6 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain EF-hand_5 PF13202.1 KFP04725.1 - 1e-07 30.9 4.3 1.9e-06 26.9 0.9 2.6 1 1 1 2 2 2 2 EF hand EF-hand_1 PF00036.27 KFP04725.1 - 1.5e-06 27.1 2.6 9.4e-06 24.5 0.5 2.5 1 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFP04725.1 - 3.6e-05 23.2 6.4 6.5e-05 22.4 0.3 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 KFP04725.1 - 0.00017 21.6 1.5 0.00034 20.6 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP04725.1 - 0.00075 19.1 2.1 0.0075 16.0 0.6 2.5 1 1 1 2 2 2 1 EF-hand domain ABM PF03992.11 KFP04725.1 - 0.0017 18.3 0.1 0.0046 16.9 0.0 1.7 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase PDZ PF00595.19 KFP04727.1 - 1.9e-14 53.5 0.1 3.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP04727.1 - 0.0016 18.2 0.1 0.0036 17.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 KFP04727.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain Ribosomal_S4 PF00163.14 KFP04728.1 - 3.5e-11 43.3 0.1 3.8e-11 43.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SRCR PF00530.13 KFP04729.1 - 1.8e-124 406.7 42.6 1.1e-32 112.2 1.9 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFP04729.1 - 5.4e-15 55.4 17.0 0.0025 17.9 0.1 4.3 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain TYW3 PF02676.9 KFP04729.1 - 4.9 6.2 4.9 51 2.8 0.0 3.4 4 0 0 4 4 4 0 Methyltransferase TYW3 SRCR PF00530.13 KFP04730.1 - 4.3e-128 418.3 45.8 1.2e-32 112.1 4.9 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFP04730.1 - 3.2e-22 78.5 13.0 5.1e-05 23.4 0.2 4.4 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain PEP-utilizers PF00391.18 KFP04730.1 - 0.01 15.4 0.0 45 3.6 0.0 3.6 4 0 0 4 4 4 0 PEP-utilising enzyme, mobile domain zf-H2C2_2 PF13465.1 KFP04731.1 - 5.6e-45 149.4 50.8 3.4e-09 36.5 0.2 6.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04731.1 - 2.7e-36 121.7 41.9 3.6e-07 30.1 1.3 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04731.1 - 1.6e-22 78.0 37.5 2.1e-05 24.5 0.1 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP04731.1 - 2.7e-18 65.5 18.5 0.0027 17.7 0.1 6.2 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP04731.1 - 2.2e-14 52.7 27.6 0.0082 16.0 0.4 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.2 KFP04731.1 - 5.1e-12 45.5 34.2 0.0026 17.9 0.8 6.2 6 0 0 6 6 6 6 Zinc-finger of C2H2 type C1_1 PF00130.17 KFP04731.1 - 1.8e-06 27.5 17.9 0.0094 15.6 1.3 4.3 2 2 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) XPA_N PF01286.13 KFP04731.1 - 1.1e-05 25.0 11.6 5 6.8 0.0 6.1 6 0 0 6 6 6 0 XPA protein N-terminal Prok-RING_1 PF14446.1 KFP04731.1 - 3.2e-05 23.5 13.0 14 5.4 0.0 6.2 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zf-CHY PF05495.7 KFP04731.1 - 0.00012 22.1 16.2 0.0096 16.0 1.7 3.3 1 1 2 3 3 3 2 CHY zinc finger BolA PF01722.13 KFP04731.1 - 0.00024 20.9 2.8 0.32 10.9 0.1 3.1 2 1 1 3 3 3 1 BolA-like protein zf-Di19 PF05605.7 KFP04731.1 - 0.00053 20.0 28.5 0.3 11.2 0.7 4.6 2 1 3 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding PHF5 PF03660.9 KFP04731.1 - 0.00067 19.6 6.5 0.48 10.4 0.1 3.0 1 1 2 3 3 3 1 PHF5-like protein C1_3 PF07649.7 KFP04731.1 - 0.00093 19.1 17.2 1.1 9.3 0.1 6.2 6 0 0 6 6 6 1 C1-like domain Zn-ribbon_8 PF09723.5 KFP04731.1 - 0.0049 16.7 22.6 6.5 6.7 0.1 5.9 4 1 1 6 6 6 0 Zinc ribbon domain LIM PF00412.17 KFP04731.1 - 0.017 15.1 19.5 0.21 11.6 1.3 4.9 1 1 4 5 5 5 0 LIM domain DZR PF12773.2 KFP04731.1 - 0.023 14.4 16.4 2.9e+03 -1.9 11.4 3.7 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.8 KFP04731.1 - 0.024 14.3 16.7 0.13 11.9 0.6 4.1 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like FYDLN_acid PF09538.5 KFP04731.1 - 0.035 14.6 6.5 2 9.0 0.2 4.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Rad50_zn_hook PF04423.9 KFP04731.1 - 0.038 13.4 15.3 1.8 8.0 0.3 5.1 3 1 2 5 5 5 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.1 KFP04731.1 - 0.08 12.6 0.1 0.08 12.6 0.1 6.6 6 2 0 6 6 6 0 zinc-finger of a C2HC-type DUF2175 PF09943.4 KFP04731.1 - 0.086 12.9 8.0 20 5.3 0.0 5.2 6 0 0 6 6 6 0 Uncharacterized protein conserved in archaea (DUF2175) DUF2225 PF09986.4 KFP04731.1 - 0.091 12.2 13.4 0.67 9.3 0.2 4.4 3 2 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-AN1 PF01428.11 KFP04731.1 - 0.17 11.8 26.1 5 7.0 0.2 6.2 5 1 1 6 6 6 0 AN1-like Zinc finger Scramblase PF03803.10 KFP04731.1 - 0.24 10.4 1.1 3.2 6.7 0.1 2.1 1 1 0 2 2 2 0 Scramblase C1_2 PF03107.11 KFP04731.1 - 0.29 11.2 22.4 4.4 7.5 0.1 5.9 6 0 0 6 6 6 0 C1 domain zf-Sec23_Sec24 PF04810.10 KFP04731.1 - 0.39 10.3 11.2 6.3 6.4 0.0 5.1 5 1 1 6 6 6 0 Sec23/Sec24 zinc finger zinc-ribbons_6 PF07191.7 KFP04731.1 - 0.44 10.3 16.0 4.7 7.0 0.1 5.5 3 2 2 5 5 5 0 zinc-ribbons FYVE PF01363.16 KFP04731.1 - 0.44 10.4 23.3 7.6 6.5 8.6 3.8 1 1 2 3 3 3 0 FYVE zinc finger zf-RING_3 PF14369.1 KFP04731.1 - 0.58 10.1 0.1 0.58 10.1 0.1 5.2 6 0 0 6 6 5 0 zinc-finger DUF2180 PF09947.4 KFP04731.1 - 0.63 9.8 13.6 1.7 8.4 0.2 3.9 1 1 3 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2180) zf-trcl PF13451.1 KFP04731.1 - 0.63 9.7 19.3 1.4 8.6 0.0 5.6 5 1 1 6 6 6 0 Probable zinc-binding domain Baculo_IE-1 PF05290.6 KFP04731.1 - 0.91 9.2 11.7 12 5.6 0.3 4.7 2 2 3 5 5 5 0 Baculovirus immediate-early protein (IE-0) zf-HIT PF04438.11 KFP04731.1 - 1.2 8.8 26.3 0.67 9.6 0.4 5.8 6 0 0 6 6 6 0 HIT zinc finger zf-BED PF02892.10 KFP04731.1 - 1.8 8.4 30.0 5.3 6.8 0.7 5.8 2 1 4 6 6 6 0 BED zinc finger zf-C2H2_2 PF12756.2 KFP04731.1 - 2 8.5 20.9 6.2 6.9 0.1 5.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_recom PF13408.1 KFP04731.1 - 2.6 8.3 19.2 1.5e+04 -7.6 13.3 4.1 1 1 0 1 1 0 0 Recombinase zinc beta ribbon domain HNH PF01844.18 KFP04731.1 - 3 7.8 24.3 3.6 7.5 0.1 5.7 6 0 0 6 6 6 0 HNH endonuclease GAGA PF09237.6 KFP04731.1 - 3.3 7.3 12.4 2.4 7.8 0.0 4.5 1 1 4 5 5 5 0 GAGA factor Rubredoxin PF00301.15 KFP04731.1 - 5.3 7.0 18.7 34 4.4 0.1 5.5 5 1 0 5 5 5 0 Rubredoxin Zn_ribbon_2 PF12674.2 KFP04731.1 - 6 7.2 7.8 19 5.7 0.8 3.2 4 0 0 4 4 3 0 Putative zinc ribbon domain C1_4 PF07975.7 KFP04731.1 - 6.9 6.7 26.4 11 6.1 2.3 4.9 1 1 4 5 5 5 0 TFIIH C1-like domain HypA PF01155.14 KFP04731.1 - 8.9 6.0 13.1 21 4.8 1.3 3.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Snf7 PF03357.16 KFP04732.1 - 1.8e-21 76.2 14.9 2e-21 76.1 10.3 1.0 1 0 0 1 1 1 1 Snf7 DUF2634 PF10934.3 KFP04732.1 - 0.049 13.4 0.3 0.079 12.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2634) YlqD PF11068.3 KFP04732.1 - 0.089 12.8 5.6 0.14 12.1 3.8 1.5 1 1 0 1 1 1 0 YlqD protein Cytochrom_B562 PF07361.6 KFP04732.1 - 0.37 11.2 6.7 0.12 12.8 0.7 2.5 2 1 0 2 2 2 0 Cytochrome b562 TPR_MLP1_2 PF07926.7 KFP04732.1 - 0.43 10.3 6.7 0.51 10.0 4.6 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HCMV_UL139 PF12507.3 KFP04732.1 - 1.1 9.3 5.2 0.24 11.5 0.5 1.8 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Seryl_tRNA_N PF02403.17 KFP04732.1 - 1.3 9.1 10.3 2.5 8.1 3.8 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PspA_IM30 PF04012.7 KFP04732.1 - 1.3 8.3 14.1 2.2 7.5 3.5 2.2 1 1 1 2 2 2 0 PspA/IM30 family DUF4140 PF13600.1 KFP04732.1 - 7.1 7.1 8.0 10 6.6 2.8 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SH3_9 PF14604.1 KFP04733.1 - 1.5e-14 53.2 0.1 2.5e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain PID PF00640.18 KFP04733.1 - 8.3e-09 35.5 0.0 3.3e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) SH3_1 PF00018.23 KFP04733.1 - 6.2e-08 31.9 0.0 1.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP04733.1 - 0.0007 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Thioredoxin_8 PF13905.1 KFP04735.1 - 3.2e-22 78.4 0.0 5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFP04735.1 - 5.4e-07 29.7 0.0 9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFP04735.1 - 0.00022 20.7 0.0 0.0003 20.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 KFP04735.1 - 0.0085 15.6 0.0 0.056 12.9 0.0 2.2 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin PF00085.15 KFP04735.1 - 0.014 15.0 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.1 KFP04735.1 - 0.13 12.3 0.0 0.68 9.9 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like AMP-binding PF00501.23 KFP04736.1 - 1.2e-73 247.9 0.0 1.5e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFP04736.1 - 8.4e-07 29.8 0.1 2.4e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TRAPP PF04051.11 KFP04737.1 - 2.6e-32 111.4 0.0 3.2e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component La PF05383.12 KFP04739.1 - 3.2e-21 74.8 0.1 5.9e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 KFP04739.1 - 0.00017 21.5 0.0 0.00056 19.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP04739.1 - 0.054 13.3 0.1 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 KFP04740.1 - 7.7e-70 235.3 0.4 1.3e-45 155.5 0.1 2.5 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 KFP04740.1 - 7.4e-25 87.7 0.3 1.5e-24 86.7 0.2 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain zf-H2C2_2 PF13465.1 KFP04742.1 - 2.6e-20 71.6 34.5 1.6e-08 34.4 1.0 5.4 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04742.1 - 5e-20 70.5 23.0 3.3e-05 23.9 0.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04742.1 - 5.5e-13 48.2 22.3 0.0011 19.1 0.1 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 KFP04742.1 - 0.00041 20.4 3.0 0.92 9.8 0.1 4.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CHORD PF04968.7 KFP04742.1 - 0.015 15.4 16.1 1.4 9.2 0.4 3.9 2 1 2 4 4 4 0 CHORD TP1 PF02079.11 KFP04742.1 - 0.017 14.8 1.7 0.065 13.0 0.0 2.3 2 0 0 2 2 2 0 Nuclear transition protein 1 Marek_A PF02124.10 KFP04742.1 - 0.05 13.0 1.1 0.076 12.4 0.8 1.3 1 1 0 1 1 1 0 Marek's disease glycoprotein A zf-H2C2_5 PF13909.1 KFP04742.1 - 0.53 10.6 0.0 0.53 10.6 0.0 4.8 4 1 0 4 4 4 0 C2H2-type zinc-finger domain PcF PF09461.5 KFP04742.1 - 0.63 9.9 4.2 17 5.4 0.1 3.2 3 0 0 3 3 3 0 Phytotoxin PcF protein zf-C2H2_6 PF13912.1 KFP04742.1 - 0.64 10.0 5.2 0.64 10.0 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger R3H PF01424.17 KFP04743.1 - 2.5e-12 46.2 0.0 6.5e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 KFP04743.1 - 3.1e-10 40.3 4.0 3.1e-10 40.3 2.8 4.3 5 0 0 5 5 5 1 SUZ domain TUSC2 PF15000.1 KFP04743.1 - 0.02 14.9 0.2 0.02 14.9 0.2 3.9 5 0 0 5 5 5 0 Tumour suppressor candidate 2 C1_1 PF00130.17 KFP04744.1 - 0.0054 16.4 6.1 0.016 14.9 4.4 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KFP04744.1 - 0.31 10.4 4.0 0.54 9.6 2.7 1.4 1 0 0 1 1 1 0 PHD-finger SHMT PF00464.14 KFP04745.1 - 5.2e-209 693.5 0.0 6.1e-209 693.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase STAT_bind PF02864.10 KFP04746.1 - 1.8e-85 286.5 3.9 2.3e-85 286.2 2.7 1.1 1 0 0 1 1 1 1 STAT protein, DNA binding domain SH2 PF00017.19 KFP04746.1 - 1.5e-09 37.4 0.0 3.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain DUF2215 PF10225.4 KFP04747.1 - 0.03 13.7 0.8 0.038 13.4 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Brevenin PF03032.10 KFP04747.1 - 8.6 6.2 6.5 19 5.1 4.5 1.6 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family DUF2215 PF10225.4 KFP04748.1 - 5.7e-21 75.0 0.0 7.7e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) NAGLU PF05089.7 KFP04748.1 - 0.039 12.7 0.2 4.9 5.8 0.0 2.0 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain BTB PF00651.26 KFP04749.1 - 8.7e-24 83.6 0.1 1.7e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP04749.1 - 3e-13 49.3 55.0 8.2e-07 29.0 3.9 9.9 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04749.1 - 1.6e-06 28.0 80.5 0.0014 18.8 2.4 9.7 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04749.1 - 0.00083 19.5 79.1 0.063 13.6 1.7 10.3 11 0 0 11 11 11 7 C2H2-type zinc finger BolA PF01722.13 KFP04749.1 - 0.02 14.8 0.7 15 5.5 0.1 3.3 2 1 1 3 3 3 0 BolA-like protein CpXC PF14353.1 KFP04749.1 - 9.5 6.1 22.9 3.8 7.4 0.2 5.1 4 2 0 5 5 5 0 CpXC protein DNA_primase_S PF01896.14 KFP04750.1 - 1.8e-31 108.9 0.0 1.9e-30 105.5 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit NAC PF01849.13 KFP04751.1 - 4.7e-26 90.0 1.2 1.1e-24 85.6 0.1 2.5 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KFP04751.1 - 0.00067 19.4 0.5 0.0014 18.3 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_Rpo13 PF12136.3 KFP04751.1 - 0.035 13.7 3.9 0.081 12.6 2.7 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain DUF2203 PF09969.4 KFP04751.1 - 4 7.6 8.2 0.9 9.7 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Casein PF00363.13 KFP04751.1 - 8 7.1 6.9 0.76 10.4 0.4 2.2 2 0 0 2 2 2 0 Casein CS PF04969.11 KFP04752.1 - 1.4e-09 38.3 0.3 1.9e-09 37.9 0.2 1.2 1 0 0 1 1 1 1 CS domain Pkinase_C PF00433.19 KFP04752.1 - 0.6 10.6 5.4 1.7 9.2 3.7 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain ATP-synt_ab PF00006.20 KFP04753.1 - 5.2e-29 101.2 0.1 8.8e-29 100.5 0.0 1.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 KFP04753.1 - 6.2e-07 29.5 0.4 1.4e-06 28.4 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 KFP04753.1 - 0.0052 15.9 0.1 0.0069 15.5 0.1 1.2 1 0 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 KFP04753.1 - 0.0086 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 KFP04753.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFP04753.1 - 0.019 14.3 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFP04753.1 - 0.04 12.7 0.1 0.048 12.4 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KFP04753.1 - 0.042 14.1 0.1 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KFP04753.1 - 0.071 13.0 0.1 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFP04753.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KFP04753.1 - 0.091 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KFP04753.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KFP04753.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 KFP04754.1 - 1.9e-21 76.5 0.1 2.6e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFP04754.1 - 5.4e-21 75.1 0.3 7.5e-21 74.7 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain MIP PF00230.15 KFP04755.1 - 2.8e-53 180.7 1.5 3.2e-53 180.5 1.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein TIMELESS PF04821.9 KFP04756.1 - 2.2e-97 325.4 0.1 3.1e-97 325.0 0.0 1.2 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 KFP04756.1 - 6.1e-35 121.1 0.0 9.9e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Timeless protein C terminal region UCH_1 PF13423.1 KFP04757.1 - 1.2e-67 228.3 0.0 1.6e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KFP04757.1 - 7.8e-08 31.7 2.1 2.1e-06 27.0 1.5 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KFP04757.1 - 2.7e-05 24.4 0.0 7.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Exonuclease Citrate_synt PF00285.16 KFP04758.1 - 2.6e-101 338.9 0.0 3e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Polyketide_cyc PF03364.15 KFP04759.1 - 2.8e-26 92.0 0.1 3.2e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KFP04759.1 - 0.00084 19.5 0.0 0.00099 19.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ank_2 PF12796.2 KFP04760.1 - 5.4e-191 619.5 72.7 5.1e-22 78.0 0.0 14.3 1 1 12 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.25 KFP04760.1 - 1.1e-169 542.5 74.8 3.9e-08 32.6 0.1 28.0 27 1 0 27 27 27 26 Ankyrin repeat Ank_4 PF13637.1 KFP04760.1 - 7.2e-150 485.0 44.8 9.6e-14 51.4 0.1 19.8 9 3 13 22 22 22 22 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP04760.1 - 6.1e-129 417.1 62.6 5.8e-12 45.4 0.0 22.0 6 6 15 23 23 23 22 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP04760.1 - 3.2e-122 386.0 58.1 1.4e-05 24.8 0.1 28.1 28 0 0 28 28 28 25 Ankyrin repeat USP8_interact PF08941.5 KFP04761.1 - 2.3e-20 72.6 3.8 2.3e-20 72.6 2.6 1.5 2 0 0 2 2 2 1 USP8 interacting Sina PF03145.11 KFP04761.1 - 1.2e-06 28.3 1.8 1.7e-06 27.8 1.2 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-RING_2 PF13639.1 KFP04761.1 - 6.5e-06 25.8 4.2 6.5e-06 25.8 2.9 2.1 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFP04761.1 - 2.1e-05 24.0 3.7 2.1e-05 24.0 2.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP04761.1 - 3.7e-05 23.6 2.5 3.7e-05 23.6 1.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP04761.1 - 3.9e-05 23.6 5.0 3.9e-05 23.6 3.5 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFP04761.1 - 0.00012 21.7 1.4 0.00012 21.7 1.0 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP04761.1 - 0.00025 20.7 3.3 0.00025 20.7 2.3 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-TRAF PF02176.13 KFP04761.1 - 0.00069 19.9 6.9 0.036 14.4 1.0 2.8 1 1 1 2 2 2 2 TRAF-type zinc finger zf-Apc11 PF12861.2 KFP04761.1 - 0.0052 16.5 2.2 0.013 15.2 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KFP04761.1 - 0.033 13.9 0.2 0.033 13.9 0.1 2.1 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KFP04761.1 - 0.033 14.0 3.1 0.033 14.0 2.1 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING IncA PF04156.9 KFP04761.1 - 0.047 13.2 1.3 0.056 13.0 0.9 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 KFP04761.1 - 0.053 13.9 5.0 0.15 12.4 3.5 1.8 1 1 0 1 1 1 0 SlyX Adeno_E4_34 PF04528.8 KFP04761.1 - 0.063 12.8 1.3 0.11 12.0 0.9 1.4 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Baculo_RING PF05883.6 KFP04761.1 - 0.081 12.7 0.6 0.36 10.6 0.1 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF1754 PF08555.5 KFP04761.1 - 0.1 13.1 0.4 0.14 12.7 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Atx10homo_assoc PF09759.4 KFP04761.1 - 0.12 12.1 1.9 0.2 11.4 0.3 1.9 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF1664 PF07889.7 KFP04761.1 - 0.14 11.9 1.1 0.24 11.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 KFP04761.1 - 1.5 7.6 8.4 1.8 7.3 5.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EF-hand_7 PF13499.1 KFP04762.1 - 4.8e-06 26.6 0.0 2.1e-05 24.5 0.0 1.8 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP04762.1 - 0.00013 21.0 1.3 0.065 12.5 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 KFP04762.1 - 0.003 17.3 0.0 0.065 13.1 0.0 2.8 3 1 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFP04762.1 - 0.038 13.6 1.0 3.8 7.1 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain pair Ets PF00178.17 KFP04763.1 - 8.1e-26 89.9 0.3 9.4e-26 89.7 0.2 1.1 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 KFP04763.1 - 0.01 15.9 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Cadherin PF00028.12 KFP04764.1 - 5.3e-10 39.4 0.0 5.6e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Cadherin domain CI-B14_5a PF07347.7 KFP04765.1 - 0.17 11.6 3.0 0.3 10.9 2.1 1.6 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) zf-H2C2_2 PF13465.1 KFP04766.1 - 5.6e-61 199.9 64.5 4.9e-10 39.1 0.5 8.4 9 0 0 9 9 8 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04766.1 - 4.2e-52 171.4 58.6 8.3e-08 32.1 0.5 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04766.1 - 9.6e-35 116.3 53.7 5.1e-05 23.3 0.3 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP04766.1 - 2.8e-28 96.8 40.5 0.00053 19.8 0.3 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP04766.1 - 5.7e-22 77.2 24.1 0.034 14.2 0.3 8.2 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KFP04766.1 - 1.1e-14 54.1 30.0 0.026 14.4 1.6 7.8 6 2 1 7 7 7 5 Zinc ribbon domain zf-RING_3 PF14369.1 KFP04766.1 - 7.4e-11 41.8 25.9 0.078 12.9 0.1 7.9 8 0 0 8 8 8 3 zinc-finger zf-Di19 PF05605.7 KFP04766.1 - 2.9e-10 40.0 30.8 0.0017 18.4 1.1 5.7 3 2 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 KFP04766.1 - 2.5e-08 33.4 22.5 0.65 9.7 0.1 7.8 8 0 0 8 8 8 2 XPA protein N-terminal zf-ribbon_3 PF13248.1 KFP04766.1 - 4.1e-08 32.1 32.0 0.5 9.6 0.3 8.1 8 0 0 8 8 8 3 zinc-ribbon domain zf-LYAR PF08790.6 KFP04766.1 - 4.4e-08 32.6 18.7 0.78 9.4 0.1 7.5 7 0 0 7 7 7 1 LYAR-type C2HC zinc finger DZR PF12773.2 KFP04766.1 - 2.2e-07 30.5 25.5 0.0011 18.7 0.5 5.1 2 2 1 3 3 3 2 Double zinc ribbon zf-CHY PF05495.7 KFP04766.1 - 7.7e-07 29.1 24.6 0.00024 21.1 2.2 4.1 1 1 1 3 3 3 3 CHY zinc finger zf-met PF12874.2 KFP04766.1 - 2.3e-06 27.6 40.9 0.44 10.8 0.7 8.1 8 0 0 8 8 8 3 Zinc-finger of C2H2 type Prok-RING_1 PF14446.1 KFP04766.1 - 3.4e-06 26.6 15.4 8.3 6.2 0.0 7.9 8 0 0 8 8 8 0 Prokaryotic RING finger family 1 zf-BED PF02892.10 KFP04766.1 - 3.2e-05 23.5 41.0 0.048 13.4 2.0 7.6 1 1 7 8 8 8 2 BED zinc finger TFIIS_C PF01096.13 KFP04766.1 - 5.1e-05 22.8 29.8 2.8 7.6 0.1 8.0 8 0 0 8 8 8 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KFP04766.1 - 6.3e-05 22.6 42.3 0.12 12.1 2.4 5.9 2 2 5 7 7 7 4 Transposase zinc-ribbon domain zf-HIT PF04438.11 KFP04766.1 - 0.00014 21.4 33.2 0.65 9.6 0.2 7.9 8 0 0 8 8 8 1 HIT zinc finger FYDLN_acid PF09538.5 KFP04766.1 - 0.00015 22.3 17.8 21 5.7 0.0 7.0 2 2 5 7 7 7 0 Protein of unknown function (FYDLN_acid) YhfH PF14149.1 KFP04766.1 - 0.00021 21.0 25.2 3.6 7.4 0.2 7.6 8 0 0 8 8 7 0 YhfH-like protein C1_3 PF07649.7 KFP04766.1 - 0.00025 21.0 24.1 7.8 6.6 0.0 7.7 8 0 0 8 8 8 0 C1-like domain zf-trcl PF13451.1 KFP04766.1 - 0.00082 18.9 21.0 1.2 8.8 0.1 7.2 8 0 0 8 8 8 1 Probable zinc-binding domain DUF329 PF03884.9 KFP04766.1 - 0.00083 18.8 19.5 7.1 6.2 0.0 7.5 8 0 0 8 8 8 0 Domain of unknown function (DUF329) zinc_ribbon_2 PF13240.1 KFP04766.1 - 0.0013 18.1 44.6 0.55 9.7 4.1 7.5 7 1 0 7 7 7 3 zinc-ribbon domain PRP21_like_P PF12230.3 KFP04766.1 - 0.0016 17.9 1.5 1.1 8.6 0.1 2.5 2 1 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein HypA PF01155.14 KFP04766.1 - 0.0021 17.7 22.4 1.2 8.8 0.3 4.9 1 1 2 3 3 3 1 Hydrogenase expression/synthesis hypA family zf-AN1 PF01428.11 KFP04766.1 - 0.0028 17.4 31.1 4.4 7.2 0.2 7.8 6 1 2 8 8 8 0 AN1-like Zinc finger DNA_RNApol_7kD PF03604.8 KFP04766.1 - 0.0042 16.5 25.2 7.5 6.1 0.1 7.9 8 0 0 8 8 8 0 DNA directed RNA polymerase, 7 kDa subunit C1_4 PF07975.7 KFP04766.1 - 0.0047 16.9 28.6 1.1 9.3 1.0 6.5 1 1 4 6 6 6 1 TFIIH C1-like domain zf-C2HC_2 PF13913.1 KFP04766.1 - 0.0047 16.5 29.5 0.52 10.0 0.8 7.4 7 0 0 7 7 7 1 zinc-finger of a C2HC-type GAGA PF09237.6 KFP04766.1 - 0.0096 15.4 23.6 1.2 8.7 0.7 5.3 3 2 2 5 5 5 2 GAGA factor CpXC PF14353.1 KFP04766.1 - 0.014 15.3 26.9 7.5 6.5 0.0 7.4 5 2 1 6 6 6 0 CpXC protein zf-IS66 PF13005.2 KFP04766.1 - 0.014 15.3 24.6 4.7 7.2 0.1 7.7 7 1 2 9 9 9 0 zinc-finger binding domain of transposase IS66 UPF0547 PF10571.4 KFP04766.1 - 0.021 14.4 37.7 3.8 7.3 0.2 8.0 8 0 0 8 8 8 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.5 KFP04766.1 - 0.027 13.9 30.6 4.7 6.7 0.1 7.8 8 0 0 8 8 8 0 A2L zinc ribbon domain zf-ISL3 PF14690.1 KFP04766.1 - 0.03 14.3 38.7 3.6 7.6 0.1 7.9 6 2 1 7 7 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.7 KFP04766.1 - 0.052 12.8 28.4 2.6 7.4 0.1 7.5 8 0 0 8 8 8 0 TFIIB zinc-binding Mut7-C PF01927.11 KFP04766.1 - 0.052 13.5 20.4 2.3 8.1 0.4 4.6 1 1 3 4 4 4 0 Mut7-C RNAse domain Zn_ribbon_recom PF13408.1 KFP04766.1 - 0.054 13.7 26.5 0.49 10.6 1.0 5.4 2 1 2 4 4 4 0 Recombinase zinc beta ribbon domain LIM PF00412.17 KFP04766.1 - 0.087 12.9 26.8 0.1 12.6 0.8 6.4 1 1 4 6 6 6 0 LIM domain TerY-C PF15616.1 KFP04766.1 - 0.15 12.0 21.1 3.5 7.5 3.7 3.7 1 1 3 4 4 4 0 TerY-C metal binding domain zinc_ribbon_5 PF13719.1 KFP04766.1 - 0.16 11.5 34.3 1.8 8.2 2.0 7.6 6 2 0 6 6 6 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 KFP04766.1 - 0.2 11.7 23.7 26 4.9 0.4 7.4 6 2 2 8 8 8 0 Ribosomal protein L44 DUF164 PF02591.10 KFP04766.1 - 0.51 10.2 24.0 30 4.5 0.1 7.4 8 0 0 8 8 8 0 Putative zinc ribbon domain zinc_ribbon_4 PF13717.1 KFP04766.1 - 1.3 8.7 35.0 4.6 7.0 1.8 7.6 7 1 0 7 7 7 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 KFP04766.1 - 1.6 8.8 26.8 2.8 8.1 0.3 6.3 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) Terminase_GpA PF05876.7 KFP04766.1 - 2 6.6 23.6 1.3 7.2 0.3 3.9 2 1 2 4 4 4 0 Phage terminase large subunit (GpA) zinc-ribbons_6 PF07191.7 KFP04766.1 - 2.1 8.2 23.8 3.3 7.5 0.4 6.2 2 2 2 4 4 4 0 zinc-ribbons Ogr_Delta PF04606.7 KFP04766.1 - 2.6 7.7 31.7 0.82 9.3 0.5 6.1 3 2 2 6 6 6 0 Ogr/Delta-like zinc finger Sgf11 PF08209.6 KFP04766.1 - 2.7 7.3 26.8 20 4.5 0.0 7.9 8 0 0 8 8 8 0 Sgf11 (transcriptional regulation protein) zf-UBP PF02148.14 KFP04766.1 - 5.2 7.2 33.0 0.91 9.6 1.5 5.9 1 1 3 5 5 5 0 Zn-finger in ubiquitin-hydrolases and other protein Elf1 PF05129.8 KFP04766.1 - 6.5 6.5 25.1 0.3 10.8 0.9 5.3 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like Yippee-Mis18 PF03226.9 KFP04766.1 - 7.3 6.7 22.0 12 5.9 2.4 5.6 2 1 3 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ion_trans PF00520.26 KFP04767.1 - 3.1e-45 153.8 7.8 3.1e-45 153.8 5.4 1.4 2 0 0 2 2 2 1 Ion transport protein 7tm_2 PF00002.19 KFP04768.1 - 5.7e-77 258.0 21.4 7e-77 257.7 14.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP04768.1 - 6.2e-11 42.1 1.6 6.2e-11 42.1 1.1 2.9 4 0 0 4 4 4 1 Hormone receptor domain DUF2138 PF09909.4 KFP04768.1 - 0.17 9.9 0.2 0.23 9.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Acyltransferase PF01553.16 KFP04769.1 - 1.6e-32 111.7 0.1 2.9e-32 110.8 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase YlqD PF11068.3 KFP04770.1 - 0.082 12.9 10.0 0.11 12.5 0.5 2.1 2 0 0 2 2 2 0 YlqD protein Microtub_bind PF13931.1 KFP04770.1 - 0.53 10.4 8.8 2 8.5 1.6 2.6 2 1 1 3 3 3 0 Kinesin-associated microtubule-binding Histone PF00125.19 KFP04771.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 HR1 PF02185.11 KFP04771.1 - 0.035 13.8 3.8 0.071 12.8 2.7 1.5 1 0 0 1 1 1 0 Hr1 repeat DivIC PF04977.10 KFP04771.1 - 2.4 7.7 5.2 1.1 8.7 2.0 1.7 2 0 0 2 2 2 0 Septum formation initiator SWIB PF02201.13 KFP04772.1 - 1.8e-21 75.6 0.1 4e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain 7tm_1 PF00001.16 KFP04775.1 - 3.8e-68 229.4 24.8 4.4e-68 229.1 17.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP04775.1 - 2.1e-15 56.5 21.0 2.5e-15 56.3 14.6 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP04775.1 - 1.8e-08 33.8 20.1 2.4e-08 33.4 13.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFP04775.1 - 4.8e-07 29.1 19.5 8e-07 28.4 13.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Serpentine_r_xa PF03383.10 KFP04775.1 - 0.011 15.5 3.6 0.011 15.5 2.5 2.5 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Herpes_US9 PF06072.6 KFP04775.1 - 0.038 13.8 1.3 0.038 13.8 0.9 2.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 GerA PF03323.8 KFP04775.1 - 4 5.4 7.6 0.11 10.6 0.6 1.9 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein C1q PF00386.16 KFP04776.1 - 2.4e-32 111.5 1.1 3e-32 111.2 0.7 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP04776.1 - 2.3e-08 33.4 13.2 3.6e-08 32.8 9.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ion_trans PF00520.26 KFP04777.1 - 2.7e-195 643.7 82.7 1.6e-58 197.3 11.3 4.4 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 KFP04777.1 - 4.2e-10 38.6 78.1 4.8e-05 21.9 0.7 9.5 6 3 2 8 8 8 6 Polycystin cation channel EphA2_TM PF14575.1 KFP04777.1 - 0.00035 20.9 0.6 28 5.1 0.0 5.4 4 0 0 4 4 4 1 Ephrin type-A receptor 2 transmembrane domain FimP PF09766.4 KFP04777.1 - 0.028 13.4 0.2 0.028 13.4 0.1 1.6 2 0 0 2 2 2 0 Fms-interacting protein B9-C2 PF07162.6 KFP04778.1 - 2.9e-47 160.5 0.2 3.3e-47 160.4 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein ENTH PF01417.15 KFP04779.1 - 7.2e-55 184.1 0.2 1.7e-54 183.0 0.2 1.7 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KFP04779.1 - 1e-06 27.6 0.1 1.5e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KFP04779.1 - 6.4e-05 22.6 0.9 0.00012 21.7 0.2 1.7 2 0 0 2 2 2 1 VHS domain UIM PF02809.15 KFP04779.1 - 0.00084 18.7 2.0 0.00084 18.7 1.4 2.4 2 0 0 2 2 2 1 Ubiquitin interaction motif Pribosyl_synth PF14572.1 KFP04780.1 - 1.2e-100 334.7 1.3 1.8e-100 334.1 0.9 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFP04780.1 - 5.1e-39 132.6 1.5 7.9e-39 131.9 0.3 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFP04780.1 - 0.00035 20.2 2.9 0.0036 17.0 1.2 2.7 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UN_NPL4 PF11543.3 KFP04780.1 - 0.02 15.1 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RelB PF04221.7 KFP04780.1 - 0.032 13.9 0.2 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 RelB antitoxin 7tm_1 PF00001.16 KFP04781.1 - 2.3e-51 174.4 21.1 3.2e-51 173.9 14.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFP04781.1 - 2e-08 33.7 13.5 2e-08 33.7 9.4 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF3043 PF11241.3 KFP04781.1 - 0.83 9.2 4.6 1.6 8.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Folliculin PF11704.3 KFP04782.1 - 1.3e-07 31.3 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Topoisom_bac PF01131.15 KFP04783.1 - 2.9e-104 349.1 0.0 4.5e-104 348.4 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 KFP04783.1 - 7.7e-35 118.5 19.9 8e-19 67.3 3.6 3.5 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.17 KFP04783.1 - 2.9e-17 62.4 0.0 7.5e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.14 KFP04783.1 - 3.9e-12 45.4 1.7 3.9e-12 45.4 1.2 3.7 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.18 KFP04783.1 - 0.0068 16.2 3.4 0.0068 16.2 2.4 2.5 2 0 0 2 2 2 1 Zinc knuckle Gelsolin PF00626.17 KFP04784.1 - 2.4e-62 206.5 2.3 5e-15 54.9 0.0 6.8 6 0 0 6 6 6 6 Gelsolin repeat LRR_8 PF13855.1 KFP04784.1 - 1.6e-33 114.2 49.3 8.9e-10 38.1 6.5 6.6 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFP04784.1 - 8.7e-33 111.4 63.3 1.7e-08 33.8 4.1 9.0 2 2 6 10 10 10 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04784.1 - 1.6e-16 57.8 53.5 0.0066 16.3 0.4 13.3 13 0 0 13 13 13 7 Leucine Rich Repeat LRR_7 PF13504.1 KFP04784.1 - 1e-08 33.9 49.5 0.15 12.3 0.5 11.6 11 0 0 11 11 11 7 Leucine rich repeat LRR_6 PF13516.1 KFP04784.1 - 0.00059 19.6 46.7 0.23 11.6 0.1 10.9 10 1 0 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.1 KFP04784.1 - 5 6.6 14.6 1.1 8.8 0.0 3.7 1 1 1 3 3 3 0 Leucine-rich repeat 2OG-FeII_Oxy_2 PF13532.1 KFP04785.1 - 1.3e-10 41.4 0.0 2.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ApoO PF09769.4 KFP04785.1 - 0.088 12.5 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O TGS PF02824.16 KFP04786.1 - 1.8e-23 82.1 0.0 3.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KFP04786.1 - 1.1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP04786.1 - 2.6e-10 39.8 0.0 4.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFP04786.1 - 0.0023 18.4 0.0 0.0067 16.9 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 KFP04786.1 - 0.0073 16.1 0.3 0.76 9.5 0.0 2.3 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 KFP04786.1 - 0.11 11.2 0.8 0.5 9.0 0.0 2.2 1 1 1 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 KFP04786.1 - 0.14 11.5 0.5 7.3 5.9 0.2 2.9 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Vac_ImportDeg PF09783.4 KFP04787.1 - 8.3e-58 194.7 5.2 9.3e-58 194.6 3.6 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Amidase_6 PF12671.2 KFP04787.1 - 0.048 13.7 1.2 0.067 13.2 0.4 1.3 1 1 0 1 1 1 0 Putative amidase domain ATP12 PF07542.6 KFP04788.1 - 8e-42 142.0 0.1 1.2e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein VHS PF00790.14 KFP04789.1 - 6.1e-45 152.3 0.2 1.8e-44 150.7 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KFP04789.1 - 4.1e-35 119.7 2.1 4.4e-34 116.4 2.3 2.0 2 0 0 2 2 2 1 GAT domain ENTH PF01417.15 KFP04789.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 ENTH domain HEAT_2 PF13646.1 KFP04789.1 - 0.11 12.7 0.3 25 5.2 0.1 2.8 3 0 0 3 3 3 0 HEAT repeats FYVE_2 PF02318.11 KFP04789.1 - 0.17 11.7 1.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger HLH PF00010.21 KFP04790.1 - 6.2e-18 64.2 1.2 1.5e-17 62.9 0.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 KFP04790.1 - 0.0077 16.5 0.5 0.017 15.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) zf-HC5HC2H PF13771.1 KFP04791.1 - 5.4e-13 48.9 9.5 5.4e-13 48.9 6.6 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFP04791.1 - 2e-09 37.4 8.8 2e-09 37.4 6.1 2.3 2 1 0 2 2 2 1 PHD-zinc-finger like domain PEMT PF04191.8 KFP04792.1 - 6.3e-32 109.8 4.9 6.3e-32 109.8 3.4 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Ras PF00071.17 KFP04793.1 - 3.6e-37 127.2 0.0 5.1e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP04793.1 - 4.9e-16 59.3 0.0 1.4e-15 57.8 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP04793.1 - 3.4e-07 29.6 0.0 6.5e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP04793.1 - 7.9e-06 25.4 0.0 4.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP04793.1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KFP04793.1 - 0.011 15.4 0.1 0.056 13.1 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 KFP04793.1 - 0.021 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Adenyl_transf PF04439.7 KFP04793.1 - 0.096 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Streptomycin adenylyltransferase AAA_22 PF13401.1 KFP04793.1 - 0.1 12.7 0.0 4.9 7.3 0.0 2.8 2 1 1 3 3 3 0 AAA domain Med9 PF07544.8 KFP04794.1 - 9.6e-21 73.3 3.3 1e-20 73.2 2.3 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 KFP04794.1 - 3.1e-07 30.4 2.9 3.5e-07 30.3 2.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF3452 PF11934.3 KFP04794.1 - 0.0044 16.3 0.2 0.0051 16.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) DASH_Duo1 PF08651.5 KFP04794.1 - 0.005 16.3 0.4 0.0068 15.9 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Duo1 4HB_MCP_1 PF12729.2 KFP04794.1 - 0.0085 15.4 0.4 0.0091 15.3 0.2 1.1 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction MinC_N PF05209.8 KFP04794.1 - 0.011 15.4 0.6 0.013 15.2 0.4 1.1 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain COG6 PF06419.6 KFP04794.1 - 0.014 13.5 2.0 0.015 13.4 1.4 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 ELK PF03789.8 KFP04794.1 - 0.018 14.7 1.8 0.15 11.8 0.3 2.3 2 0 0 2 2 2 0 ELK domain PilJ PF13675.1 KFP04794.1 - 0.021 15.1 0.3 0.025 14.9 0.2 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term TBPIP PF07106.8 KFP04794.1 - 0.025 14.1 3.3 0.028 13.9 2.3 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HAP1_N PF04849.8 KFP04794.1 - 0.033 13.1 3.9 0.051 12.5 2.7 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Myb_DNA-bind_4 PF13837.1 KFP04794.1 - 0.037 14.1 0.3 0.047 13.8 0.2 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain CHASE3 PF05227.8 KFP04794.1 - 0.045 13.4 1.3 0.058 13.0 0.9 1.1 1 0 0 1 1 1 0 CHASE3 domain Fib_alpha PF08702.5 KFP04794.1 - 0.048 13.7 4.2 0.068 13.3 2.9 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GrpE PF01025.14 KFP04794.1 - 0.049 13.1 0.7 0.052 13.0 0.5 1.0 1 0 0 1 1 1 0 GrpE DUF2305 PF10230.4 KFP04794.1 - 0.064 12.6 0.5 0.074 12.4 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Sec63 PF02889.11 KFP04794.1 - 0.072 12.3 0.4 0.073 12.2 0.3 1.0 1 0 0 1 1 1 0 Sec63 Brl domain DUF342 PF03961.8 KFP04794.1 - 0.075 11.4 3.0 0.085 11.2 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_GP20 PF06810.6 KFP04794.1 - 0.076 12.4 1.9 0.089 12.2 1.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 SRP_SPB PF02978.14 KFP04794.1 - 0.084 13.1 1.3 0.13 12.5 0.9 1.3 1 1 0 1 1 1 0 Signal peptide binding domain FlaC_arch PF05377.6 KFP04794.1 - 0.094 12.6 2.4 0.31 10.9 0.4 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4047 PF13256.1 KFP04794.1 - 0.1 12.5 1.2 0.12 12.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) zf-CpG_bind_C PF12269.3 KFP04794.1 - 0.11 12.0 0.8 0.12 11.8 0.6 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain HSBP1 PF06825.7 KFP04794.1 - 0.12 12.0 0.4 0.12 12.0 0.3 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Enkurin PF13864.1 KFP04794.1 - 0.12 12.5 5.6 2.8 8.2 0.1 2.0 1 1 1 2 2 2 0 Calmodulin-binding BSD PF03909.12 KFP04794.1 - 0.13 12.0 1.2 0.75 9.5 0.2 2.0 2 0 0 2 2 2 0 BSD domain XPC-binding PF09280.6 KFP04794.1 - 0.14 11.6 6.1 4.1 6.9 0.0 2.3 2 1 0 2 2 2 0 XPC-binding domain IncA PF04156.9 KFP04794.1 - 0.17 11.4 3.9 0.21 11.1 2.7 1.1 1 0 0 1 1 1 0 IncA protein Med30 PF11315.3 KFP04794.1 - 0.24 11.5 6.6 1.6 8.8 4.5 1.8 1 1 0 1 1 1 0 Mediator complex subunit 30 DUF2232 PF09991.4 KFP04794.1 - 0.32 9.9 1.2 0.37 9.7 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DASH_Dad3 PF08656.5 KFP04794.1 - 0.33 10.6 2.6 0.79 9.4 0.3 1.9 1 1 1 2 2 2 0 DASH complex subunit Dad3 WXG100 PF06013.7 KFP04794.1 - 0.4 10.7 3.0 7.3 6.6 0.0 2.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG MitMem_reg PF13012.1 KFP04794.1 - 1.4 8.9 5.0 2 8.5 1.1 2.0 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function FliJ PF02050.11 KFP04794.1 - 1.6 8.8 7.9 3.7 7.6 5.5 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein COMP PF11598.3 KFP04794.1 - 3.3 7.8 5.4 2.6 8.2 0.2 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein NT5C PF06941.7 KFP04795.1 - 4.3e-80 267.7 0.0 4.9e-80 267.5 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) PCI PF01399.22 KFP04796.1 - 5e-19 68.5 1.5 1e-18 67.5 0.1 2.2 2 0 0 2 2 2 1 PCI domain YjfB_motility PF14070.1 KFP04796.1 - 0.0032 17.2 0.1 0.013 15.2 0.1 2.0 1 0 0 1 1 1 1 Putative motility protein TPR_8 PF13181.1 KFP04796.1 - 0.0046 16.6 1.9 0.047 13.4 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP04796.1 - 0.0068 15.9 2.5 0.015 14.8 0.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFP04796.1 - 0.016 15.1 0.9 0.28 11.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFP04796.1 - 0.069 13.1 2.3 0.15 12.0 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFP04796.1 - 0.46 10.1 2.7 1.6 8.4 0.3 2.6 3 0 0 3 3 3 0 TPR repeat Folliculin PF11704.3 KFP04797.1 - 8.5e-56 188.1 0.0 1.4e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PH PF00169.24 KFP04798.1 - 5.5e-19 68.3 0.4 1.1e-16 60.8 0.2 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFP04798.1 - 2.8e-05 24.3 11.5 0.00038 20.6 1.2 4.8 4 2 1 5 5 5 2 Pleckstrin homology domain TPR_MLP1_2 PF07926.7 KFP04798.1 - 8.1 6.1 50.8 0.41 10.4 11.9 5.2 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 KFP04798.1 - 8.4 6.2 14.3 1 9.1 4.9 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACI-CRD2 PF09305.5 KFP04799.1 - 3.8e-14 52.1 19.7 8.6e-13 47.8 4.5 4.1 4 1 1 5 5 5 2 TACI, cysteine-rich domain UCH PF00443.24 KFP04800.1 - 3.8e-64 216.3 0.2 5e-64 216.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP04800.1 - 5.1e-29 101.6 0.1 7.7e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFP04800.1 - 4.2e-14 52.4 10.7 4.2e-14 52.4 7.4 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.1 KFP04800.1 - 0.14 11.4 11.4 0.14 11.4 0.2 3.4 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase adh_short PF00106.20 KFP04801.1 - 2.7e-31 108.7 0.1 4.3e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFP04801.1 - 1.1e-15 58.0 0.2 1.5e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFP04801.1 - 1.1e-12 48.0 0.1 1.8e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFP04801.1 - 5.9e-06 25.6 0.1 0.00015 21.0 0.0 2.7 2 2 1 3 3 3 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFP04801.1 - 1.4e-05 25.1 0.2 5.9e-05 23.1 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFP04801.1 - 0.00022 20.2 0.1 0.00031 19.7 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KFP04801.1 - 0.002 18.2 0.1 0.0091 16.1 0.1 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KFP04801.1 - 0.0032 17.3 0.1 0.0072 16.1 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 KFP04801.1 - 0.0067 15.8 0.5 0.02 14.3 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KFP04801.1 - 0.049 12.7 0.3 0.4 9.7 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Mito_morph_reg PF14972.1 KFP04802.1 - 5.4e-80 266.6 0.4 6.9e-80 266.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial morphogenesis regulator Acetyltransf_CG PF14542.1 KFP04803.1 - 8.8e-22 76.7 0.2 1.1e-21 76.5 0.1 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.19 KFP04803.1 - 0.0016 18.4 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KFP04803.1 - 0.049 13.7 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3222 PF11519.3 KFP04803.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) Pkinase PF00069.20 KFP04804.1 - 2.8e-54 184.0 0.0 3.2e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04804.1 - 7.9e-40 136.5 0.0 9.8e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP04804.1 - 1.5e-08 33.9 0.0 5.4e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFP04804.1 - 0.0028 16.5 0.2 0.0044 15.8 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KFP04804.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP04804.1 - 0.039 13.5 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KFP04804.1 - 0.076 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family IRK PF01007.15 KFP04806.1 - 4.7e-171 568.1 0.1 5.6e-171 567.8 0.1 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel IRK_N PF08466.5 KFP04806.1 - 1.7e-26 91.8 0.3 3.2e-26 90.9 0.2 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel N-terminal Ion_trans_2 PF07885.11 KFP04806.1 - 0.039 13.6 7.2 0.12 12.1 5.0 1.8 1 1 0 1 1 1 0 Ion channel WRW PF10206.4 KFP04807.1 - 2.1e-29 101.6 0.0 2.6e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f zf-CCCH PF00642.19 KFP04808.1 - 6.6e-18 63.9 33.1 2.3e-07 30.3 0.3 5.7 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 KFP04808.1 - 1.1e-05 25.0 3.6 1.1e-05 25.0 2.5 3.8 6 0 0 6 6 6 1 Zinc knuckle zf-CCHC_3 PF13917.1 KFP04808.1 - 0.048 13.3 8.1 0.093 12.4 1.5 3.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 KFP04808.1 - 0.13 11.8 3.8 6.2 6.3 0.6 3.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCCH_2 PF14608.1 KFP04808.1 - 0.21 11.6 0.5 0.21 11.6 0.3 6.8 7 0 0 7 7 7 0 Zinc finger C-x8-C-x5-C-x3-H type PPR_2 PF13041.1 KFP04809.1 - 1.2e-47 159.5 0.0 1.2e-14 53.9 0.0 9.1 6 3 3 9 9 9 8 PPR repeat family PPR_3 PF13812.1 KFP04809.1 - 6e-22 76.0 0.0 0.0038 17.4 0.0 8.9 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.15 KFP04809.1 - 3.2e-19 67.4 12.5 7.3e-07 28.7 0.1 9.1 10 1 0 10 10 10 4 PPR repeat PPR_1 PF12854.2 KFP04809.1 - 1.5e-11 43.5 3.6 0.0012 18.3 0.0 8.0 9 0 0 9 9 9 2 PPR repeat MNE1 PF13762.1 KFP04809.1 - 0.19 11.8 1.2 5.4 7.0 0.2 3.4 2 2 1 3 3 3 0 Mitochondrial splicing apparatus component G10 PF01125.12 KFP04810.1 - 4.5e-53 178.7 8.5 4.9e-53 178.5 5.9 1.0 1 0 0 1 1 1 1 G10 protein Metallothio_11 PF02066.10 KFP04810.1 - 1.9 8.3 10.1 0.25 11.2 3.9 1.7 1 1 1 2 2 2 0 Metallothionein family 11 PP28 PF10252.4 KFP04811.1 - 3.3e-32 110.3 17.4 3.3e-32 110.3 12.1 2.4 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 WD40 PF00400.27 KFP04812.1 - 8.7e-22 76.1 12.2 8.2e-09 35.0 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Rax2 PF12768.2 KFP04812.1 - 0.00017 20.9 0.7 0.015 14.4 0.1 2.3 2 0 0 2 2 2 2 Cortical protein marker for cell polarity eIF2A PF08662.6 KFP04812.1 - 0.00028 20.6 1.9 0.14 11.8 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KFP04812.1 - 0.014 14.8 0.2 3.1 7.3 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 KFP04812.1 - 0.022 14.4 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 KFP04813.1 - 9.3e-19 66.5 22.1 3.7e-07 29.7 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 KFP04813.1 - 2.9e-05 23.4 0.1 0.0017 17.6 0.0 2.5 3 0 0 3 3 3 2 Cortical protein marker for cell polarity Arm PF00514.18 KFP04814.1 - 1.5e-77 253.0 14.2 4.9e-11 42.0 0.0 9.4 9 0 0 9 9 9 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP04814.1 - 3.1e-20 72.2 1.7 4.5e-06 26.8 0.0 6.3 2 2 4 6 6 6 5 HEAT repeats IBB PF01749.15 KFP04814.1 - 2.6e-19 69.1 1.1 4e-19 68.5 0.8 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFP04814.1 - 6.5e-17 61.4 3.2 1.9e-05 25.0 0.0 5.7 7 0 0 7 7 7 3 HEAT-like repeat HEAT PF02985.17 KFP04814.1 - 1e-08 34.5 2.1 0.014 15.4 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat V-ATPase_H_C PF11698.3 KFP04814.1 - 0.0047 16.8 0.0 3.3 7.6 0.0 3.4 3 1 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.11 KFP04814.1 - 0.02 15.3 6.1 21 5.9 0.0 6.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat BLOC1_2 PF10046.4 KFP04816.1 - 0.012 15.7 5.5 0.012 15.7 3.8 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EF-hand_7 PF13499.1 KFP04816.1 - 0.031 14.4 0.0 0.088 12.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KFP04816.1 - 0.044 13.1 0.0 0.096 12.0 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 KFP04816.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain ACCA PF03255.9 KFP04816.1 - 0.096 12.2 2.9 0.75 9.3 1.2 2.5 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MinC_N PF05209.8 KFP04816.1 - 0.1 12.4 0.2 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain DUF4633 PF15464.1 KFP04816.1 - 0.12 12.1 2.2 0.2 11.5 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) Vps51 PF08700.6 KFP04816.1 - 0.18 11.6 3.1 2.9 7.8 0.1 2.9 1 1 2 3 3 3 0 Vps51/Vps67 PspA_IM30 PF04012.7 KFP04816.1 - 0.19 11.0 11.1 0.75 9.1 2.7 2.3 2 0 0 2 2 2 0 PspA/IM30 family DUF4600 PF15372.1 KFP04816.1 - 0.36 11.0 7.5 0.8 9.9 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) HisKA_3 PF07730.8 KFP04816.1 - 0.56 10.5 5.7 0.9 9.9 0.7 2.7 2 1 0 2 2 2 0 Histidine kinase DLD PF14878.1 KFP04816.1 - 0.63 10.1 5.2 1.3 9.1 2.2 2.4 1 1 1 2 2 2 0 Death-like domain of SPT6 COG2 PF06148.6 KFP04816.1 - 0.64 9.8 10.2 2 8.2 2.8 2.3 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Hemerythrin PF01814.18 KFP04816.1 - 2.4 8.3 8.7 0.57 10.3 0.3 3.3 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain TMF_TATA_bd PF12325.3 KFP04816.1 - 2.6 7.7 15.6 2.1 8.1 6.1 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 KFP04816.1 - 3.6 7.6 9.2 2.5 8.1 3.7 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 KFP04816.1 - 5 6.9 18.5 15 5.4 0.6 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KFP04816.1 - 6.4 6.3 20.2 2.9e+02 0.9 14.0 2.2 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 KFP04816.1 - 8.3 6.8 12.4 7.5 6.9 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 KFP04816.1 - 8.4 6.2 10.7 6.1 6.6 0.2 2.9 3 0 0 3 3 2 0 Homeobox associated leucine zipper Acyl-CoA_dh_1 PF00441.19 KFP04818.1 - 1e-39 136.0 0.2 1.4e-33 116.0 0.1 2.7 2 1 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFP04818.1 - 2.5e-23 82.7 0.0 7.8e-23 81.2 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFP04818.1 - 4.4e-22 77.3 0.1 7.7e-22 76.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFP04818.1 - 9.3e-09 35.6 0.0 4.2e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Sec7 PF01369.15 KFP04819.1 - 6.8e-62 208.5 0.1 1.9e-61 207.0 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain IQ PF00612.22 KFP04819.1 - 0.18 11.5 1.1 0.62 9.8 0.2 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif bZIP_2 PF07716.10 KFP04820.1 - 0.00043 20.0 3.0 0.00061 19.5 2.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFP04820.1 - 0.0095 15.8 1.9 0.011 15.7 1.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 KFP04820.1 - 0.013 15.4 0.7 0.014 15.3 0.5 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 KFP04820.1 - 0.015 14.8 2.1 0.016 14.6 1.5 1.2 1 0 0 1 1 1 0 Septum formation initiator BMFP PF04380.8 KFP04820.1 - 0.029 14.5 2.4 0.038 14.1 1.7 1.2 1 0 0 1 1 1 0 Membrane fusogenic activity Phage_GP20 PF06810.6 KFP04820.1 - 0.033 13.6 0.4 0.033 13.6 0.3 1.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4439 PF14530.1 KFP04820.1 - 0.064 13.7 0.0 0.064 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) DUF2205 PF10224.4 KFP04820.1 - 0.079 12.5 0.6 0.079 12.5 0.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) HSBP1 PF06825.7 KFP04820.1 - 0.084 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF1875 PF08961.5 KFP04820.1 - 0.088 12.1 1.2 0.087 12.1 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) DUF2680 PF10925.3 KFP04820.1 - 0.091 12.6 0.6 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) ORF6C PF10552.4 KFP04820.1 - 0.098 12.3 1.0 0.1 12.3 0.7 1.0 1 0 0 1 1 1 0 ORF6C domain Pox_A_type_inc PF04508.7 KFP04820.1 - 0.11 12.3 1.7 0.5 10.2 0.7 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CASP_C PF08172.7 KFP04820.1 - 0.17 10.8 1.0 0.17 10.8 0.7 1.1 1 0 0 1 1 1 0 CASP C terminal K-box PF01486.12 KFP04820.1 - 0.27 11.0 2.9 0.3 10.8 2.0 1.2 1 0 0 1 1 1 0 K-box region CENP-Q PF13094.1 KFP04820.1 - 0.3 11.1 4.9 0.31 11.0 3.4 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Rab5-bind PF09311.6 KFP04820.1 - 0.34 10.7 5.5 0.42 10.4 3.8 1.2 1 0 0 1 1 1 0 Rabaptin-like protein ATG16 PF08614.6 KFP04820.1 - 0.35 10.6 3.3 0.35 10.6 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KFP04820.1 - 0.56 9.7 5.4 0.62 9.6 3.8 1.0 1 0 0 1 1 1 0 IncA protein Big_2 PF02368.13 KFP04821.1 - 3.9e-13 49.0 13.2 5.8e-08 32.5 0.0 6.7 6 0 0 6 6 6 2 Bacterial Ig-like domain (group 2) CHU_C PF13585.1 KFP04821.1 - 0.12 12.2 0.9 0.37 10.6 0.2 2.2 2 0 0 2 2 2 0 C-terminal domain of CHU protein family Hist_deacetyl PF00850.14 KFP04822.1 - 1e-59 202.4 0.0 1.2e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Shisa PF13908.1 KFP04823.1 - 2.2e-25 89.8 12.2 2.2e-25 89.8 8.4 1.4 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator BTG PF07742.7 KFP04824.1 - 4.5e-31 106.8 0.0 5.9e-31 106.4 0.0 1.2 1 0 0 1 1 1 1 BTG family Ins_P5_2-kin PF06090.7 KFP04825.1 - 2.8e-95 318.9 1.4 3.2e-95 318.7 0.9 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase LRR_8 PF13855.1 KFP04826.1 - 2e-48 161.9 21.0 3.3e-15 55.5 0.1 6.1 5 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 KFP04826.1 - 4.2e-36 121.9 29.8 2.6e-06 26.9 0.2 9.2 3 1 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04826.1 - 7.5e-28 92.2 22.9 0.36 11.0 0.0 13.9 13 1 1 14 14 14 8 Leucine Rich Repeat LRR_6 PF13516.1 KFP04826.1 - 9e-16 56.1 28.8 0.028 14.4 0.0 11.8 12 1 1 13 13 13 4 Leucine Rich repeat LRR_7 PF13504.1 KFP04826.1 - 1e-13 49.0 17.1 4.8 7.8 0.0 12.0 12 0 0 12 12 12 3 Leucine rich repeat VWC PF00093.13 KFP04826.1 - 1.2e-10 41.3 14.5 2.4e-10 40.3 10.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type C domain LRR_5 PF13306.1 KFP04826.1 - 1.4e-08 34.4 0.0 0.00085 19.0 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFP04826.1 - 1.3e-06 28.1 2.6 0.02 14.4 0.2 4.8 1 1 3 5 5 5 2 Leucine-rich repeat FNIP PF05725.7 KFP04826.1 - 0.19 11.6 12.7 6 6.9 0.2 4.7 4 1 0 4 4 4 0 FNIP Repeat Amnionless PF14828.1 KFP04826.1 - 0.41 9.0 10.0 0.63 8.4 6.9 1.2 1 0 0 1 1 1 0 Amnionless LRR_8 PF13855.1 KFP04827.1 - 9.4e-67 220.6 45.4 3.6e-11 42.6 0.5 9.4 5 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFP04827.1 - 9.6e-46 152.7 60.9 8.3e-06 25.2 1.2 12.6 5 3 5 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04827.1 - 4e-30 99.1 44.7 0.0055 16.5 0.1 19.4 19 2 2 21 21 21 7 Leucine Rich Repeat LRR_5 PF13306.1 KFP04827.1 - 2.2e-19 69.4 8.0 3.8e-06 26.6 0.0 5.8 2 2 2 5 5 5 4 Leucine rich repeats (6 copies) LRRNT PF01462.13 KFP04827.1 - 9.2e-12 44.1 32.4 3.9e-07 29.3 1.8 6.7 8 0 0 8 8 8 2 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFP04827.1 - 3.6e-11 41.3 43.3 0.041 14.0 0.0 16.4 20 0 0 20 20 20 3 Leucine rich repeat LRR_6 PF13516.1 KFP04827.1 - 1.8e-09 36.6 51.5 8.3 6.8 0.0 16.4 18 0 0 18 18 18 2 Leucine Rich repeat LRR_9 PF14580.1 KFP04827.1 - 1.9e-08 34.0 11.2 0.031 13.8 0.1 4.8 4 1 0 4 4 4 3 Leucine-rich repeat DUF2999 PF11212.3 KFP04827.1 - 0.077 13.0 2.0 21 5.2 0.0 4.6 6 0 0 6 6 6 0 Protein of unknown function (DUF2999) FNIP PF05725.7 KFP04827.1 - 4.3 7.3 22.8 19 5.2 0.6 6.9 5 1 1 6 6 6 0 FNIP Repeat LRR_8 PF13855.1 KFP04828.1 - 3.3e-21 74.7 4.5 5.9e-09 35.5 0.0 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP04828.1 - 1.1e-16 59.9 4.1 2e-05 24.0 0.1 4.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04828.1 - 1.7e-14 51.5 1.3 0.033 14.1 0.0 6.5 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_5 PF13306.1 KFP04828.1 - 1.4e-06 28.0 0.4 0.0097 15.6 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFP04828.1 - 1.4e-06 27.7 1.0 5.9 7.2 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 KFP04828.1 - 4.6e-06 25.9 4.5 2.9 8.4 0.0 5.7 5 0 0 5 5 5 1 Leucine rich repeat CENP-P PF13096.1 KFP04829.1 - 4.4e-31 107.5 0.6 4.4e-31 107.5 0.4 2.1 3 0 0 3 3 3 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P TSC22 PF01166.13 KFP04829.1 - 0.053 13.4 1.1 0.12 12.3 0.8 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Kinesin-relat_1 PF12711.2 KFP04829.1 - 0.061 13.7 3.1 0.17 12.3 2.2 1.8 1 1 0 1 1 1 0 Kinesin motor DUF3829 PF12889.2 KFP04829.1 - 0.14 11.3 1.0 0.28 10.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) SlyX PF04102.7 KFP04829.1 - 3.2 8.2 7.7 1.1 9.7 0.3 3.1 3 1 1 4 4 4 0 SlyX zf-HC5HC2H PF13771.1 KFP04830.1 - 4.9e-07 29.8 0.7 4.9e-07 29.8 0.5 3.5 3 2 0 3 3 3 1 PHD-like zinc-binding domain PHD PF00628.24 KFP04830.1 - 2.7e-06 26.9 31.3 0.0004 20.0 5.1 3.4 3 0 0 3 3 3 3 PHD-finger zf-RING_2 PF13639.1 KFP04830.1 - 0.00032 20.4 10.0 0.00032 20.4 6.9 3.6 3 1 0 3 3 3 1 Ring finger domain zf-HC5HC2H_2 PF13832.1 KFP04830.1 - 0.011 15.7 1.0 0.011 15.7 0.7 3.3 2 1 1 3 3 3 0 PHD-zinc-finger like domain DUF2545 PF10810.3 KFP04830.1 - 0.091 13.1 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) FANCL_C PF11793.3 KFP04830.1 - 1.1 9.2 11.0 4 7.4 0.1 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain SPRY PF00622.23 KFP04831.1 - 1.5e-25 89.6 0.1 3e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.1 KFP04831.1 - 1.3e-08 34.3 8.4 1.3e-08 34.3 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP04831.1 - 4.7e-05 23.3 13.4 0.00014 21.7 9.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP04831.1 - 0.014 15.0 14.0 0.039 13.6 9.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP04831.1 - 0.022 14.4 12.2 0.057 13.1 8.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KFP04831.1 - 0.06 13.1 10.7 0.2 11.5 7.4 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 KFP04831.1 - 9.3 6.2 10.8 25 4.8 7.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING NTP_transferase PF00483.18 KFP04832.1 - 1.3e-25 90.1 0.0 2.8e-25 89.0 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KFP04832.1 - 1.8e-13 49.3 16.7 7.9e-08 31.4 3.6 3.6 1 1 3 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFP04832.1 - 1.8e-05 24.2 3.3 1.8e-05 24.2 2.3 2.9 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IPK PF03770.11 KFP04833.1 - 7.4e-65 218.2 0.0 1.1e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase UBA_e1_C PF09358.5 KFP04834.1 - 1.3e-09 38.2 0.0 1.5e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain DUF2390 PF09523.5 KFP04834.1 - 0.0085 16.2 0.2 0.011 15.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2390) UAE_UbL PF14732.1 KFP04834.1 - 0.01 15.8 0.3 0.016 15.3 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiF PF00899.16 KFP04835.1 - 3.9e-43 146.5 0.0 1e-32 112.7 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KFP04835.1 - 9.4e-35 118.0 0.1 3.7e-25 87.2 0.0 3.2 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KFP04835.1 - 1.2e-12 46.9 0.1 1.2e-12 46.9 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KFP04835.1 - 0.041 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 MoeZ/MoeB domain DAG1 PF05454.6 KFP04837.1 - 1.5e-153 510.1 7.7 2.3e-153 509.4 5.3 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.1 KFP04837.1 - 0.0058 16.3 0.1 0.0058 16.3 0.1 2.3 2 0 0 2 2 2 1 TMEM154 protein family Peptidase_S9 PF00326.16 KFP04838.1 - 2.4e-28 98.8 0.0 3.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFP04838.1 - 9.1e-14 51.8 5.3 2.5e-13 50.4 3.7 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP04838.1 - 8.1e-13 48.3 0.0 1.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFP04838.1 - 4.3e-05 22.8 0.0 6.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 KFP04838.1 - 0.00085 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KFP04838.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.6 KFP04838.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 KFP04838.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 KFP04839.1 - 1.9e-35 122.0 0.0 2.9e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFP04839.1 - 1.7e-16 60.7 1.5 3.6e-16 59.7 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP04839.1 - 2.7e-16 59.6 0.0 5.5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP04839.1 - 1.8e-07 30.9 0.0 1.6e-05 24.6 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFP04839.1 - 1.9e-06 27.6 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KFP04839.1 - 3.2e-06 26.5 0.0 8.3e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KFP04839.1 - 8.1e-05 22.1 0.0 0.35 10.2 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KFP04839.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 KFP04839.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DPPIV_N PF00930.16 KFP04839.1 - 0.081 11.5 0.0 6 5.3 0.1 2.3 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Esterase PF00756.15 KFP04839.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Tannase PF07519.6 KFP04839.1 - 0.15 10.7 0.0 3.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Tannase and feruloyl esterase Esterase_phd PF10503.4 KFP04839.1 - 0.16 11.2 0.4 0.47 9.6 0.3 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase PhoPQ_related PF10142.4 KFP04839.1 - 0.18 10.2 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 KFP04839.1 - 0.23 9.9 0.0 2 6.8 0.0 2.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Reo_sigmaC PF04582.7 KFP04840.1 - 0.0046 16.1 5.0 0.23 10.6 0.5 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein WEMBL PF05701.6 KFP04840.1 - 0.015 13.8 32.1 0.6 8.5 14.3 2.3 1 1 2 3 3 3 0 Weak chloroplast movement under blue light DUF2383 PF09537.5 KFP04840.1 - 0.14 12.4 5.3 3.6 7.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Filament PF00038.16 KFP04840.1 - 0.2 11.0 28.5 0.41 10.0 19.7 1.4 1 1 0 1 1 1 0 Intermediate filament protein MAD PF05557.8 KFP04840.1 - 0.22 9.5 28.4 0.34 8.9 19.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Cast PF10174.4 KFP04840.1 - 0.37 8.7 32.7 0.15 10.0 1.8 2.6 1 1 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone GAS PF13851.1 KFP04840.1 - 0.43 9.7 36.7 0.67 9.1 10.5 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FimP PF09766.4 KFP04840.1 - 0.43 9.5 22.0 0.012 14.6 3.8 2.2 2 0 0 2 2 2 0 Fms-interacting protein Laminin_II PF06009.7 KFP04840.1 - 0.59 9.8 21.5 0.11 12.2 4.8 2.8 2 1 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 KFP04840.1 - 0.9 8.1 34.0 0.38 9.3 10.1 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4201 PF13870.1 KFP04840.1 - 1.1 8.6 29.2 3.5 7.0 8.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 KFP04840.1 - 1.3 8.8 37.2 16 5.3 8.3 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KSR1-SAM PF13543.1 KFP04840.1 - 1.5 8.5 15.9 0.1 12.3 2.1 3.0 1 1 2 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 DUF87 PF01935.12 KFP04840.1 - 4.3 7.1 17.8 0.92 9.2 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 KFP04840.1 - 5.2 4.8 18.1 8 4.1 12.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RTBV_P46 PF06216.6 KFP04840.1 - 5.3 5.7 11.1 3.2 6.5 0.1 2.7 2 1 1 3 3 3 0 Rice tungro bacilliform virus P46 protein DUF1664 PF07889.7 KFP04840.1 - 5.5 6.7 24.9 0.87 9.3 6.2 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 KFP04840.1 - 7 6.4 32.2 1.1 9.1 7.6 2.9 2 1 0 2 2 2 0 Tropomyosin like Na_trans_assoc PF06512.8 KFP04840.1 - 7.3 6.4 14.1 40 4.0 9.8 1.9 1 1 0 1 1 1 0 Sodium ion transport-associated DUF3450 PF11932.3 KFP04840.1 - 7.4 5.7 18.6 8.7 5.5 3.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Uds1 PF15456.1 KFP04840.1 - 7.5 6.5 23.8 2.2 8.2 0.2 3.5 1 1 2 3 3 3 0 Up-regulated During Septation APG6 PF04111.7 KFP04840.1 - 9.1 5.2 32.0 5.9 5.8 8.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Pkinase PF00069.20 KFP04841.1 - 6.5e-59 199.1 0.1 8.4e-59 198.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04841.1 - 2.1e-23 82.7 0.0 2.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP04841.1 - 0.00026 20.0 0.0 0.0029 16.6 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KFP04841.1 - 0.017 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KFP04842.1 - 3.1e-87 291.9 0.0 4.1e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sema PF01403.14 KFP04842.1 - 6.3e-44 150.1 0.0 8.8e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain Pkinase PF00069.20 KFP04842.1 - 1e-38 132.9 0.0 1.7e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 KFP04842.1 - 1.2e-22 79.7 0.2 2e-09 37.3 0.0 4.5 4 0 0 4 4 4 3 IPT/TIG domain Kinase-like PF14531.1 KFP04842.1 - 0.0048 15.9 0.1 0.0086 15.0 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Mon1 PF03164.9 KFP04843.1 - 2.9e-181 602.6 1.2 3.4e-181 602.3 0.9 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 RRM_6 PF14259.1 KFP04844.1 - 1.2e-13 50.7 0.0 1.3e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 KFP04844.1 - 2.4e-05 24.0 0.9 7.2e-05 22.4 0.6 1.9 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 KFP04844.1 - 0.034 14.0 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP04844.1 - 0.16 11.6 0.0 9.6 5.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sema PF01403.14 KFP04845.1 - 6.5e-113 377.5 0.0 5.3e-67 226.2 0.0 2.1 2 0 0 2 2 2 2 Sema domain PSI PF01437.20 KFP04845.1 - 9.3e-05 22.5 9.8 0.00028 20.9 6.8 1.8 1 0 0 1 1 1 1 Plexin repeat I-set PF07679.11 KFP04845.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFP04845.1 - 0.00026 21.0 0.0 0.00081 19.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP04845.1 - 0.0081 16.0 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP04845.1 - 0.01 15.9 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin domain SNF2_N PF00176.18 KFP04846.1 - 6.5e-53 179.4 0.0 1.2e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFP04846.1 - 8.2e-13 48.0 0.0 2.3e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP04846.1 - 0.00021 21.1 0.0 0.0019 18.0 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFP04846.1 - 0.1 12.7 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF506 PF04720.7 KFP04846.1 - 6 6.4 11.8 79 2.7 7.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF506) SPOC PF07744.8 KFP04847.1 - 6.2e-27 94.4 0.0 1.5e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.17 KFP04847.1 - 4.3e-25 87.1 0.0 3.8e-14 52.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP04847.1 - 6.2e-19 67.7 0.0 4.1e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP04847.1 - 3.8e-15 55.4 0.0 3.4e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP04847.1 - 5.3e-05 23.0 0.0 0.00044 20.0 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFP04847.1 - 0.0021 17.8 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RR_TM4-6 PF06459.7 KFP04847.1 - 5.7 6.7 7.8 8.5 6.1 5.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Armet PF10208.4 KFP04848.1 - 6.2e-56 188.3 1.8 6.8e-56 188.1 1.3 1.0 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Cauli_DNA-bind PF03310.8 KFP04848.1 - 0.024 14.4 1.3 0.044 13.6 0.9 1.4 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein HeH PF12949.2 KFP04848.1 - 0.026 14.0 0.1 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 HeH/LEM domain RBD-FIP PF09457.5 KFP04848.1 - 0.36 10.6 1.8 2.7 7.8 0.2 2.2 2 0 0 2 2 2 0 FIP domain Ded_cyto PF06920.8 KFP04849.1 - 1.7e-55 187.1 0.6 3.6e-55 186.0 0.4 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFP04849.1 - 1.8e-40 138.5 0.0 6.2e-40 136.8 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Pkinase PF00069.20 KFP04850.1 - 1.6e-63 214.2 0.0 2.8e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04850.1 - 1.7e-29 102.6 0.0 2.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFP04850.1 - 7.5e-07 28.4 0.1 1.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP04850.1 - 0.00042 19.3 0.0 0.00097 18.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 KFP04850.1 - 0.017 14.7 0.0 0.084 12.4 0.0 2.0 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2132 PF09905.4 KFP04850.1 - 0.059 13.3 0.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) YrbL-PhoP_reg PF10707.4 KFP04850.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KFP04850.1 - 0.12 12.0 0.0 1 9.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH2 PF00017.19 KFP04851.1 - 1.6e-13 50.2 0.0 3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.11 KFP04851.1 - 3.9e-13 49.0 0.9 1e-12 47.6 0.6 1.8 1 0 0 1 1 1 1 SOCS box Methyltransf_26 PF13659.1 KFP04852.1 - 2.2e-19 69.6 0.0 5e-19 68.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFP04852.1 - 6.1e-15 54.9 0.0 1.4e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KFP04852.1 - 1.4e-13 51.3 0.0 2.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP04852.1 - 9.3e-11 41.5 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFP04852.1 - 1.2e-07 31.1 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KFP04852.1 - 9.4e-07 28.3 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 KFP04852.1 - 8.1e-06 25.5 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 KFP04852.1 - 1.7e-05 23.9 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KFP04852.1 - 2e-05 24.8 0.0 4.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP04852.1 - 5.4e-05 23.6 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP04852.1 - 0.00057 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KFP04852.1 - 0.004 17.9 0.0 0.0092 16.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP04852.1 - 0.0054 16.4 0.0 0.03 14.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 KFP04852.1 - 0.019 14.4 0.0 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 DNA methylase Met_10 PF02475.11 KFP04852.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 KFP04852.1 - 0.038 13.5 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 KFP04852.1 - 0.038 13.5 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KFP04852.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_3 PF01596.12 KFP04852.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_5 PF01795.14 KFP04852.1 - 0.14 11.3 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 MraW methylase family TehB PF03848.9 KFP04852.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Herpes_gE PF02480.11 KFP04853.1 - 0.0067 14.7 0.0 0.0074 14.6 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 KFP04853.1 - 0.017 14.5 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4446 PF14584.1 KFP04853.1 - 0.063 13.1 0.0 0.081 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF1469 PF07332.6 KFP04853.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) CEP19 PF14933.1 KFP04853.1 - 0.1 12.8 0.1 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 CEP19-like protein TM1586_NiRdase PF14512.1 KFP04854.1 - 0.054 12.6 0.2 0.056 12.6 0.1 1.0 1 0 0 1 1 1 0 Putative TM nitroreductase Epimerase_Csub PF13950.1 KFP04854.1 - 0.08 12.8 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit VWA PF00092.23 KFP04855.1 - 5.3e-10 39.3 0.0 6.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFP04855.1 - 7.7e-08 32.6 0.0 9.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Cache_1 PF02743.13 KFP04855.1 - 0.00028 20.3 0.0 0.00066 19.1 0.0 1.7 1 0 0 1 1 1 1 Cache domain VWA_3 PF13768.1 KFP04855.1 - 0.00049 19.8 0.0 0.0007 19.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Cytochrom_B561 PF03188.11 KFP04857.1 - 5.9e-31 107.1 9.1 8.8e-31 106.5 6.3 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4131 PF13567.1 KFP04857.1 - 0.066 12.6 9.8 0.14 11.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NPR2 PF06218.6 KFP04858.1 - 1.3e-112 376.6 7.8 2.8e-95 319.5 2.9 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 KFP04858.1 - 0.052 12.0 0.0 0.25 9.8 0.0 2.0 2 1 1 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2738 PF10927.3 KFP04858.1 - 0.075 12.0 0.1 0.31 10.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2738) zf-MYND PF01753.13 KFP04859.1 - 5e-10 39.0 18.8 5e-10 39.0 13.0 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 KFP04859.1 - 0.093 12.3 7.6 0.16 11.5 5.3 1.4 1 0 0 1 1 1 0 HIT zinc finger RA PF00788.18 KFP04860.1 - 1.1e-16 61.0 1.7 1.7e-16 60.5 0.1 2.1 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFP04860.1 - 0.073 13.0 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Ras-binding domain of Byr2 TUSC2 PF15000.1 KFP04861.1 - 3.9e-31 107.3 0.0 4.2e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Tumour suppressor candidate 2 DUF346 PF03984.8 KFP04861.1 - 0.066 12.6 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) Glyco_hydro_56 PF01630.13 KFP04862.1 - 7.4e-138 458.7 0.6 9.1e-138 458.5 0.4 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF PF00008.22 KFP04862.1 - 0.0056 16.6 3.9 0.16 11.9 0.1 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.8 KFP04862.1 - 0.071 13.2 13.6 1.4 9.1 3.5 2.6 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_56 PF01630.13 KFP04863.1 - 2.7e-125 417.4 0.1 3.2e-125 417.2 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase EGF_2 PF07974.8 KFP04863.1 - 0.008 16.3 9.6 0.27 11.4 0.7 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.22 KFP04863.1 - 0.33 10.9 2.6 10 6.1 0.4 2.6 2 0 0 2 2 2 0 EGF-like domain 6PF2K PF01591.13 KFP04864.1 - 2e-102 340.9 0.8 2e-102 340.9 0.5 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFP04864.1 - 4.3e-36 124.3 0.0 7.9e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFP04864.1 - 2.4e-09 37.2 0.0 6.7e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KFP04864.1 - 0.00018 20.7 0.2 0.00035 19.8 0.1 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFP04864.1 - 0.00029 21.6 0.6 0.0022 18.7 0.1 2.6 2 1 1 3 3 3 1 AAA domain Prefoldin PF02996.12 KFP04864.1 - 0.00063 19.3 1.2 0.0009 18.8 0.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit Zeta_toxin PF06414.7 KFP04864.1 - 0.008 15.2 0.0 0.021 13.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin His_Phos_2 PF00328.17 KFP04864.1 - 0.032 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA_18 PF13238.1 KFP04864.1 - 0.051 13.8 0.2 0.39 11.0 0.0 2.4 2 1 1 3 3 3 0 AAA domain Pkinase PF00069.20 KFP04865.1 - 4.9e-65 219.2 0.0 7.1e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04865.1 - 8.4e-38 129.9 0.0 1.6e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFP04865.1 - 5.3e-31 106.1 20.5 1.5e-16 59.8 5.1 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFP04865.1 - 4.4e-09 36.7 1.8 8.4e-09 35.8 1.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFP04865.1 - 0.00067 18.6 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF4206 PF13901.1 KFP04865.1 - 0.0013 18.3 12.6 0.023 14.2 2.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4206) zf-RING-like PF08746.6 KFP04865.1 - 0.025 14.5 19.8 0.22 11.5 4.5 2.7 2 0 0 2 2 2 0 RING-like domain C1_3 PF07649.7 KFP04865.1 - 0.028 14.4 14.2 0.027 14.4 2.1 3.4 2 1 0 2 2 2 0 C1-like domain Prok-RING_1 PF14446.1 KFP04865.1 - 0.033 13.9 14.4 0.15 11.7 2.2 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.2 KFP04865.1 - 0.063 13.1 13.7 0.15 11.9 2.1 2.7 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 KFP04865.1 - 0.067 12.8 18.4 0.17 11.5 2.4 2.6 2 0 0 2 2 2 0 PHD-finger PHD_2 PF13831.1 KFP04865.1 - 0.3 10.4 10.5 1.9 7.8 1.5 2.8 2 0 0 2 2 2 0 PHD-finger DUF2318 PF10080.4 KFP04865.1 - 1 9.1 11.3 0.11 12.2 1.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-Mss51 PF13824.1 KFP04865.1 - 7.4 6.5 9.6 0.64 9.9 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Rft-1 PF04506.8 KFP04866.1 - 2.9e-103 346.1 28.4 9.5e-103 344.4 19.7 1.7 1 1 0 1 1 1 1 Rft protein Phtf-FEM1B_bdg PF12129.3 KFP04866.1 - 0.34 10.2 8.2 0.089 12.1 3.1 1.9 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Sec62 PF03839.11 KFP04866.1 - 6.6 6.0 9.8 0.54 9.6 2.0 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 MBT PF02820.13 KFP04867.1 - 1.2e-85 281.4 0.5 3.9e-24 84.3 0.1 4.4 4 0 0 4 4 4 4 mbt repeat DUF3588 PF12140.3 KFP04867.1 - 2e-42 144.0 0.1 5.2e-42 142.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3588) SAM_1 PF00536.25 KFP04867.1 - 1.8e-09 37.6 0.0 3.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP04867.1 - 1.5e-06 27.9 0.0 3.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFP04867.1 - 0.00059 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 KFP04867.1 - 0.0094 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Anophelin PF10731.4 KFP04867.1 - 4.9 7.3 6.1 11 6.1 4.3 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF3661 PF12400.3 KFP04868.1 - 9.2e-30 103.3 5.3 1.6e-29 102.5 3.7 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein VIT PF08487.5 KFP04870.1 - 1.9e-47 159.7 2.1 6.5e-47 158.0 1.5 2.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KFP04870.1 - 4.7e-24 85.0 0.1 7.7e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFP04870.1 - 2.7e-20 72.6 0.0 5.2e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFP04870.1 - 7.4e-20 71.7 0.1 1.3e-19 70.9 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFP04870.1 - 8e-08 32.3 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 KFP04870.1 - 5.3e-07 28.9 0.0 9.2e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 KFP04870.1 - 0.00027 20.9 0.2 0.00065 19.7 0.1 1.6 1 0 0 1 1 1 1 VWA-like domain (DUF2201) DUF1194 PF06707.6 KFP04870.1 - 0.039 12.9 0.1 0.1 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Ribosomal_TL5_C PF14693.1 KFP04870.1 - 0.046 13.9 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein TL5, C-terminal domain Spectrin PF00435.16 KFP04870.1 - 0.064 13.5 2.9 0.37 11.1 0.4 2.5 2 0 0 2 2 2 0 Spectrin repeat ITI_HC_C PF06668.7 KFP04871.1 - 1.9e-75 252.4 0.0 3.6e-75 251.5 0.0 1.5 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus VIT PF08487.5 KFP04871.1 - 3.3e-47 159.0 3.4 6.9e-47 157.9 2.4 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KFP04871.1 - 1.7e-17 63.6 0.0 2.8e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFP04871.1 - 5e-16 58.7 0.0 9.8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFP04871.1 - 7.5e-16 58.7 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KFP04871.1 - 2.9e-08 33.7 0.0 5.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 KFP04871.1 - 0.0082 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein RPAP1_N PF08621.5 KFP04871.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal DUF2201 PF09967.4 KFP04871.1 - 0.12 12.3 0.1 1.5 8.8 0.1 2.5 1 1 0 1 1 1 0 VWA-like domain (DUF2201) SPC12 PF06645.8 KFP04872.1 - 7.3e-34 115.4 0.3 8.4e-34 115.2 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 KFP04872.1 - 0.0028 16.4 0.0 0.0031 16.3 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF443 PF04276.7 KFP04872.1 - 0.067 12.6 0.1 0.077 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF443) MerC PF03203.9 KFP04872.1 - 0.07 13.5 0.0 0.082 13.2 0.0 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein SdpI PF13630.1 KFP04872.1 - 0.12 12.0 1.2 0.15 11.7 0.9 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family Glyco_transf_8 PF01501.15 KFP04873.1 - 5.9e-48 163.3 0.1 7e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_3 PF13641.1 KFP04873.1 - 0.075 12.8 1.2 17 5.1 0.0 2.8 2 1 1 3 3 3 0 Glycosyltransferase like family 2 Bromodomain PF00439.20 KFP04874.1 - 4.7e-114 372.5 26.2 2.5e-23 81.7 0.1 6.6 6 0 0 6 6 6 6 Bromodomain BAH PF01426.13 KFP04874.1 - 4.9e-51 171.4 3.8 6.6e-27 93.6 0.9 2.7 2 0 0 2 2 2 2 BAH domain HMG_box PF00505.14 KFP04874.1 - 2.2e-14 53.4 0.6 2.2e-14 53.4 0.4 2.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP04874.1 - 1.3e-10 41.5 1.2 3.7e-10 40.0 0.9 1.8 1 0 0 1 1 1 1 HMG-box domain UPF0640 PF15114.1 KFP04875.1 - 6.2e-37 124.9 3.9 6.8e-37 124.7 2.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 5_nucleotid PF05761.9 KFP04876.1 - 4.7e-159 529.6 6.6 5.4e-159 529.4 4.6 1.0 1 0 0 1 1 1 1 5' nucleotidase family PX PF00787.19 KFP04878.1 - 2.1e-19 69.3 2.5 2.5e-19 69.1 1.7 1.0 1 0 0 1 1 1 1 PX domain tRNA_bind PF01588.15 KFP04878.1 - 0.046 13.5 0.0 0.05 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative tRNA binding domain RBD-FIP PF09457.5 KFP04878.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 FIP domain V-ATPase_H_C PF11698.3 KFP04878.1 - 0.13 12.1 0.4 0.17 11.8 0.3 1.3 1 1 0 1 1 1 0 V-ATPase subunit H EF-hand_8 PF13833.1 KFP04879.1 - 3.1e-30 103.5 15.2 6.7e-15 54.4 0.2 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFP04879.1 - 5.1e-27 91.0 24.2 1e-08 33.8 0.7 4.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KFP04879.1 - 1.6e-26 92.2 9.7 3.5e-16 59.1 4.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP04879.1 - 3.3e-22 76.3 14.6 1.8e-07 30.4 1.3 4.9 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFP04879.1 - 1.1e-13 49.8 22.7 1.2e-06 27.5 0.2 5.0 5 1 1 6 6 6 3 EF hand EF-hand_9 PF14658.1 KFP04879.1 - 3.8e-12 45.9 0.6 5.6e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFP04879.1 - 1.9e-06 27.5 7.4 0.019 14.6 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFP04879.1 - 7e-05 22.8 0.8 0.0027 17.6 0.2 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 KFP04879.1 - 0.0023 17.6 0.2 0.11 12.2 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB UPF0154 PF03672.8 KFP04879.1 - 0.026 14.1 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF1707 PF08044.6 KFP04879.1 - 0.03 14.0 0.4 1 9.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_10 PF14788.1 KFP04879.1 - 0.054 13.1 0.9 0.054 13.1 0.6 2.9 3 1 1 4 4 3 0 EF hand vATP-synt_AC39 PF01992.11 KFP04879.1 - 0.066 12.3 0.7 0.08 12.0 0.5 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit PolyA_pol_arg_C PF12626.2 KFP04879.1 - 0.086 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus PTS_2-RNA PF01885.11 KFP04879.1 - 0.1 11.8 0.0 0.57 9.4 0.0 1.9 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF21 PF01595.15 KFP04879.1 - 0.12 11.6 0.1 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 EMG1 PF03587.9 KFP04879.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase RNA_pol_Rpb4 PF03874.11 KFP04879.1 - 0.15 12.0 2.4 11 6.0 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 EFhand_Ca_insen PF08726.5 KFP04879.1 - 0.16 11.9 0.9 0.46 10.4 0.3 2.0 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF1456 PF07308.8 KFP04879.1 - 0.2 11.7 2.7 6.3 6.9 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1456) HSF_DNA-bind PF00447.12 KFP04880.1 - 5.7e-18 64.9 0.1 6.7e-18 64.7 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding PI-PLC-Y PF00387.14 KFP04880.1 - 0.044 13.7 0.4 0.9 9.5 0.1 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, Y domain DSPc PF00782.15 KFP04881.1 - 2.8e-43 146.6 0.0 3.8e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFP04881.1 - 7e-05 22.2 0.0 9.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFP04881.1 - 0.0016 18.5 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate WD40 PF00400.27 KFP04882.1 - 3e-81 264.6 21.6 1.2e-12 47.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFP04882.1 - 1.5e-10 41.1 0.2 7.9e-06 25.7 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFP04882.1 - 0.00011 20.5 0.1 0.54 8.5 0.0 3.0 1 1 2 3 3 3 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 KFP04882.1 - 0.00047 19.4 1.1 0.37 10.1 0.0 3.6 4 0 0 4 4 4 2 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 KFP04882.1 - 0.011 14.0 0.0 0.32 9.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) Syntaxin-6_N PF09177.6 KFP04882.1 - 0.036 14.4 0.4 0.07 13.5 0.3 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Aminotran_1_2 PF00155.16 KFP04883.1 - 9.5e-79 264.9 0.0 1.3e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.5 KFP04883.1 - 3.4e-22 78.4 4.0 1.3e-19 70.1 2.7 2.5 1 1 0 1 1 1 1 5-aminolevulinate synthase presequence Cys_Met_Meta_PP PF01053.15 KFP04883.1 - 2.5e-07 29.3 0.0 1.8e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KFP04883.1 - 1.5e-06 27.2 0.0 2.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFP04883.1 - 0.00039 19.6 0.0 0.00079 18.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFP04883.1 - 0.0022 17.0 0.5 0.008 15.2 0.4 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cofilin_ADF PF00241.15 KFP04884.1 - 4e-25 88.1 0.3 2.8e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.27 KFP04884.1 - 4.1e-21 74.0 0.8 7.5e-08 31.9 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 KFP04884.1 - 0.016 13.4 0.0 2.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PP2C PF00481.16 KFP04885.1 - 5.2e-35 121.0 0.0 6.8e-16 58.4 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KFP04885.1 - 2e-05 24.3 0.0 0.056 13.1 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFP04885.1 - 4.5e-05 22.9 0.0 0.041 13.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C DUF4147 PF13660.1 KFP04886.1 - 1.6e-77 259.8 0.2 2e-77 259.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 KFP04886.1 - 2e-35 121.1 0.3 3.6e-35 120.2 0.2 1.4 1 0 0 1 1 1 1 MOFRL family HAUS-augmin3 PF14932.1 KFP04887.1 - 7.7e-46 156.3 11.8 7.7e-46 156.3 8.2 3.2 3 2 0 3 3 3 1 HAUS augmin-like complex subunit 3 Sema PF01403.14 KFP04888.1 - 6.3e-152 506.0 0.0 7.7e-152 505.7 0.0 1.1 1 0 0 1 1 1 1 Sema domain ig PF00047.20 KFP04888.1 - 1.1e-05 25.5 0.0 0.00032 20.7 0.0 2.7 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP04888.1 - 7.5e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain PSI PF01437.20 KFP04888.1 - 0.0019 18.3 8.9 0.0047 17.0 6.2 1.7 1 0 0 1 1 1 1 Plexin repeat I-set PF07679.11 KFP04888.1 - 0.0035 17.1 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP04888.1 - 0.019 15.0 0.0 0.071 13.2 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain Peptidase_M20 PF01546.23 KFP04889.1 - 8.9e-37 126.4 0.0 1.2e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFP04889.1 - 1.8e-13 50.2 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFP04889.1 - 0.00028 20.6 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Abhydrolase_6 PF12697.2 KFP04890.1 - 7e-17 62.0 0.4 4.3e-10 39.8 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP04890.1 - 2.4e-11 43.6 0.0 1e-06 28.4 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFP04890.1 - 3.5e-11 43.0 0.0 3.9e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFP04890.1 - 0.00062 19.1 0.0 0.00081 18.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KFP04890.1 - 0.019 14.8 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.8 KFP04890.1 - 0.054 12.9 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KFP04891.1 - 6.2e-14 52.4 0.7 2.3e-08 34.2 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP04891.1 - 4.4e-07 29.7 0.0 5.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP04891.1 - 5.7e-05 22.7 0.1 0.00053 19.6 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KFP04891.1 - 0.074 12.3 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family KH_1 PF00013.24 KFP04892.1 - 9.8e-45 150.0 13.0 7.7e-18 63.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFP04892.1 - 3.1e-34 116.0 20.0 1.5e-11 43.6 2.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFP04892.1 - 2.5e-11 42.9 5.9 0.00032 20.2 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFP04892.1 - 2.2e-07 30.4 1.3 0.014 14.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFP04892.1 - 0.00056 19.6 4.4 4 7.3 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain RRM_6 PF14259.1 KFP04893.1 - 1.5e-29 101.7 0.0 1.7e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 KFP04893.1 - 1.3e-18 66.4 2.7 2.7e-18 65.4 1.9 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 KFP04893.1 - 1.3e-15 56.7 0.0 2.8e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 KFP04893.1 - 5.8e-11 41.2 3.5 1.1e-10 40.4 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_5 PF13893.1 KFP04893.1 - 5.5e-09 35.7 0.1 0.0015 18.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KFP04893.1 - 7.4e-08 32.1 1.2 7.4e-08 32.1 0.9 2.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site GSIII_N PF12437.3 KFP04893.1 - 0.0019 17.6 0.6 0.0041 16.5 0.4 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal zf-C2H2_4 PF13894.1 KFP04893.1 - 0.055 13.8 0.2 0.055 13.8 0.1 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP04893.1 - 0.15 12.4 0.2 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sema PF01403.14 KFP04894.1 - 4.7e-171 569.1 0.0 5.5e-171 568.8 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFP04894.1 - 0.00044 20.3 8.2 0.0012 18.9 5.6 1.8 1 0 0 1 1 1 1 Plexin repeat G-alpha PF00503.15 KFP04895.1 - 2.1e-128 428.3 1.3 2.5e-128 428.0 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP04895.1 - 1.1e-14 54.1 2.8 4e-11 42.4 0.2 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP04895.1 - 5.6e-05 22.4 0.7 0.086 11.9 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KFP04895.1 - 0.01 16.3 0.3 0.83 10.1 0.0 3.0 1 1 0 2 2 2 0 Miro-like protein DUF2951 PF11166.3 KFP04895.1 - 0.016 15.0 0.3 0.049 13.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) AAA_29 PF13555.1 KFP04895.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 KFP04896.1 - 4.2e-127 424.0 4.0 4.7e-127 423.8 2.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP04896.1 - 8.2e-14 51.2 0.1 7.6e-13 48.0 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KFP04896.1 - 0.12 12.8 0.8 5.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein Aa_trans PF01490.13 KFP04897.1 - 1.1e-07 30.7 1.9 1.3e-07 30.5 1.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sema PF01403.14 KFP04898.1 - 1.4e-166 554.3 0.0 1.6e-166 554.1 0.0 1.0 1 0 0 1 1 1 1 Sema domain PSI PF01437.20 KFP04898.1 - 0.00082 19.4 7.3 0.00082 19.4 5.0 1.9 2 0 0 2 2 2 1 Plexin repeat OAS1_C PF10421.4 KFP04899.1 - 2.4e-64 216.3 0.1 4.7e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus ubiquitin PF00240.18 KFP04899.1 - 6.7e-23 79.8 0.3 5e-17 61.0 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 KFP04899.1 - 2.7e-10 39.7 0.1 1.2e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFP04899.1 - 7.1e-10 39.0 0.2 0.00083 19.5 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-like domain NTP_transf_2 PF01909.18 KFP04899.1 - 3.3e-05 24.1 0.0 9.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain V-ATPase_H_N PF03224.9 KFP04899.1 - 0.071 12.2 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 V-ATPase subunit H IFRD PF05004.8 KFP04900.1 - 3.4e-86 289.1 0.2 4.1e-86 288.8 0.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 KFP04900.1 - 7.6e-25 86.8 0.5 2.4e-24 85.2 0.3 1.8 1 0 0 1 1 1 1 Interferon-related protein conserved region Glyco_hydro_56 PF01630.13 KFP04901.1 - 3.6e-119 397.3 0.0 4.2e-119 397.1 0.0 1.0 1 0 0 1 1 1 1 Hyaluronidase WD40 PF00400.27 KFP04902.1 - 7.3e-46 152.4 10.1 4.5e-08 32.6 0.3 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANF_receptor PF01094.23 KFP04903.1 - 1.1e-90 303.8 0.2 1.4e-90 303.5 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFP04903.1 - 8.7e-74 247.8 15.4 1.4e-73 247.1 10.7 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFP04903.1 - 3e-15 55.6 8.5 8.5e-15 54.2 5.9 1.8 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFP04903.1 - 8.2e-11 41.8 0.0 3.9e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein GyrI-like PF06445.10 KFP04904.1 - 1.5e-05 25.0 0.0 3.6e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 GyrI-like small molecule binding domain UCH PF00443.24 KFP04905.1 - 1.1e-91 306.7 0.0 2.2e-91 305.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.1 KFP04905.1 - 1e-28 98.8 0.1 2.6e-28 97.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain UCH_1 PF13423.1 KFP04905.1 - 1.2e-24 87.2 1.3 5.3e-14 52.3 0.0 3.5 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFP04905.1 - 3.7e-21 75.3 0.3 9.8e-21 74.0 0.2 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 KFP04905.1 - 9.2e-06 25.2 0.1 0.00032 20.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal DUF4606 PF15379.1 KFP04905.1 - 0.043 13.9 0.2 6 6.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4606) Zn-ribbon_8 PF09723.5 KFP04905.1 - 0.044 13.7 2.6 0.92 9.5 0.2 3.0 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 KFP04905.1 - 0.16 11.2 5.5 2.7 7.2 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF106 PF01956.11 KFP04906.1 - 1.8e-36 125.2 4.6 3.2e-36 124.3 0.3 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF106 Transketolase_N PF00456.16 KFP04907.1 - 1.3e-81 274.0 0.0 2.2e-81 273.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFP04907.1 - 1.6e-41 141.7 0.0 3.2e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFP04907.1 - 6.2e-30 103.6 0.4 1.4e-29 102.5 0.3 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 KFP04907.1 - 1.4e-08 33.8 0.0 3.4e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFP04907.1 - 7.9e-06 24.9 0.0 0.00062 18.7 0.0 2.5 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KFP04907.1 - 1.4e-05 24.6 0.2 0.00065 19.2 0.1 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 KFP04907.1 - 0.0055 15.3 0.1 0.022 13.3 0.0 1.8 1 1 1 2 2 2 1 XFP N-terminal domain DCP1 PF06058.8 KFP04908.1 - 1.5e-34 118.6 0.1 2.6e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family GMC_oxred_N PF00732.14 KFP04909.1 - 2e-96 322.6 0.0 2.6e-96 322.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFP04909.1 - 1.5e-40 138.7 0.0 2.5e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KFP04909.1 - 0.00017 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFP04909.1 - 0.0012 17.8 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFP04909.1 - 0.003 17.5 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFP04909.1 - 0.0043 16.0 0.0 0.032 13.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFP04909.1 - 0.015 15.3 0.0 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFP04909.1 - 0.069 13.0 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Actin PF00022.14 KFP04910.1 - 2.1e-31 108.7 0.0 2.9e-30 105.0 0.0 2.1 1 1 0 1 1 1 1 Actin DUF2763 PF10961.3 KFP04911.1 - 3.6e-25 88.1 0.1 3.9e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) VWA_N PF08399.6 KFP04912.1 - 2.3e-41 141.2 0.3 5.3e-41 140.0 0.2 1.7 1 0 0 1 1 1 1 VWA N-terminal Cache_1 PF02743.13 KFP04912.1 - 2.2e-30 104.0 0.1 2.1e-29 100.9 0.0 2.5 2 0 0 2 2 2 1 Cache domain VWA_2 PF13519.1 KFP04912.1 - 5.2e-16 59.2 0.0 8.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFP04912.1 - 1.3e-15 57.3 0.0 2.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFP04912.1 - 5.8e-13 48.9 0.0 9.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFP04912.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein LRR_8 PF13855.1 KFP04913.1 - 1.9e-27 94.7 22.7 5.6e-14 51.6 2.7 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFP04913.1 - 5.8e-13 48.1 17.4 3.2e-06 26.6 1.8 4.0 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP04913.1 - 1.5e-07 30.4 19.4 0.0077 16.1 0.1 5.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_5 PF13306.1 KFP04913.1 - 1.6e-06 27.8 0.0 6.1e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFP04913.1 - 1.5e-05 24.5 3.8 0.032 13.8 0.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 KFP04913.1 - 0.0004 20.1 11.9 0.082 13.1 0.1 5.0 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KFP04913.1 - 0.00044 20.0 7.7 0.76 10.0 0.1 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRRNT PF01462.13 KFP04913.1 - 0.0013 18.1 1.8 0.0013 18.1 1.2 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain wnt PF00110.14 KFP04915.1 - 8.3e-120 399.6 23.6 9.5e-120 399.4 16.3 1.0 1 0 0 1 1 1 1 wnt family Cast PF10174.4 KFP04916.1 - 8.3e-283 940.1 159.8 9.6e-283 939.9 110.8 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone AAA_13 PF13166.1 KFP04916.1 - 3.9e-05 22.3 31.8 3.9e-05 22.3 22.0 5.0 1 1 4 5 5 5 2 AAA domain IncA PF04156.9 KFP04916.1 - 0.00032 20.3 48.8 0.0014 18.2 14.0 8.3 2 1 6 8 8 8 3 IncA protein DUF869 PF05911.6 KFP04916.1 - 0.0036 15.6 10.5 0.0036 15.6 7.3 7.1 3 1 4 7 7 7 4 Plant protein of unknown function (DUF869) Lebercilin PF15619.1 KFP04916.1 - 0.0054 16.1 15.2 0.0054 16.1 10.5 8.3 3 3 4 7 7 7 3 Ciliary protein causing Leber congenital amaurosis disease Reo_sigmaC PF04582.7 KFP04916.1 - 7.4 5.6 48.2 0.12 11.5 5.3 6.9 1 1 4 7 7 7 0 Reovirus sigma C capsid protein CCDC66 PF15236.1 KFP04917.1 - 6.5e-56 188.2 37.5 6.5e-56 188.2 26.0 4.5 5 0 0 5 5 5 2 Coiled-coil domain-containing protein 66 DUF3715 PF12509.3 KFP04918.1 - 8.6e-60 201.3 0.0 3.5e-59 199.3 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) RhoGEF PF00621.15 KFP04919.1 - 8.1e-40 136.6 0.1 1.5e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KFP04919.1 - 3.7e-08 33.3 0.3 2.3e-07 30.8 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFP04919.1 - 3.1e-05 24.0 0.0 6.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PH domain zf-Di19 PF05605.7 KFP04919.1 - 0.17 12.0 2.1 0.21 11.7 0.2 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SEFIR PF08357.6 KFP04920.1 - 8.5e-57 191.4 0.7 1.8e-56 190.3 0.5 1.6 1 0 0 1 1 1 1 SEFIR domain fn3 PF00041.16 KFP04920.1 - 0.022 14.8 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 0 Fibronectin type III domain DUF2141 PF09912.4 KFP04920.1 - 0.096 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) TIR_2 PF13676.1 KFP04920.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 TIR domain Homeobox PF00046.24 KFP04921.1 - 4.9e-24 83.7 0.4 9.9e-24 82.7 0.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP04921.1 - 0.0035 17.0 0.2 0.0094 15.6 0.0 1.7 2 0 0 2 2 2 1 Homeobox KN domain PID PF00640.18 KFP04922.1 - 6.7e-13 48.8 3.1 1.7e-12 47.5 0.0 3.2 3 1 1 4 4 4 1 Phosphotyrosine interaction domain (PTB/PID) PH PF00169.24 KFP04922.1 - 6.9e-06 26.2 0.0 5.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KFP04922.1 - 0.0087 16.2 0.6 0.071 13.2 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain DUF948 PF06103.6 KFP04922.1 - 2 8.3 5.5 25 4.8 0.9 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.2 KFP04923.1 - 3.8e-75 248.2 20.5 4.3e-22 78.2 0.1 5.1 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFP04923.1 - 1.1e-51 170.1 17.9 4.7e-08 32.4 0.1 10.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 KFP04923.1 - 4.6e-45 147.0 13.2 1.7e-05 24.5 0.0 10.5 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.1 KFP04923.1 - 1.3e-40 137.0 8.2 8.8e-11 42.0 0.0 7.7 4 1 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP04923.1 - 6e-30 102.5 19.4 6.1e-06 26.3 0.0 9.3 5 2 5 10 10 10 8 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFP04923.1 - 1.3e-13 50.5 7.3 1.9e-13 50.0 4.2 2.0 2 0 0 2 2 2 1 SOCS box Exo_endo_phos PF03372.18 KFP04924.1 - 1e-20 74.7 0.0 1.4e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFP04924.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Arf PF00025.16 KFP04925.1 - 1.6e-72 242.3 0.2 1.8e-72 242.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP04925.1 - 1.6e-14 53.6 0.0 1.7e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP04925.1 - 4.9e-13 48.6 0.0 5.8e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFP04925.1 - 7.7e-11 41.5 0.0 7.8e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFP04925.1 - 2.1e-10 39.8 0.4 1e-09 37.6 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 KFP04925.1 - 1.2e-08 35.4 0.0 1.7e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFP04925.1 - 8.7e-06 25.6 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KFP04925.1 - 0.081 11.9 0.1 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KFP04925.1 - 0.085 12.2 0.2 0.25 10.7 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SPA PF08616.5 KFP04926.1 - 4e-16 58.7 0.2 2.7e-14 52.8 0.0 2.6 2 0 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.16 KFP04926.1 - 1.7e-07 31.1 5.7 1.8e-07 31.0 2.3 2.2 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.4 KFP04926.1 - 0.0019 16.7 0.0 0.0037 15.8 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 RAM PF15320.1 KFP04926.1 - 0.16 12.2 0.2 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein FHA PF00498.21 KFP04927.1 - 1e-16 60.7 0.1 4.4e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 FHA domain HrpB7 PF09486.5 KFP04927.1 - 0.0023 17.8 0.6 0.0023 17.8 0.4 6.8 3 1 2 6 6 6 2 Bacterial type III secretion protein (HrpB7) AAA_13 PF13166.1 KFP04927.1 - 3.6 5.9 84.4 0.028 12.9 19.3 3.4 1 1 1 3 3 3 0 AAA domain Filamin PF00630.14 KFP04928.1 - 0 1262.7 50.8 4e-20 72.2 0.1 24.1 24 0 0 24 24 24 24 Filamin/ABP280 repeat Big_1 PF02369.11 KFP04928.1 - 3.3e-19 68.6 0.8 0.41 10.5 0.0 13.3 15 0 0 15 15 15 4 Bacterial Ig-like domain (group 1) CH PF00307.26 KFP04928.1 - 2.6e-17 62.8 0.0 1.9e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Y_Y_Y PF07495.8 KFP04928.1 - 7.1e-17 60.9 22.8 0.51 10.1 0.0 14.1 16 0 0 16 16 16 5 Y_Y_Y domain Big_3_4 PF13754.1 KFP04928.1 - 7.8e-08 32.5 33.7 1.7 9.0 0.2 14.4 16 1 1 17 17 17 2 Bacterial Ig-like domain (group 3) DUF2141 PF09912.4 KFP04928.1 - 0.00027 20.5 2.0 20 4.8 0.0 7.2 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2141) PapC_N PF13954.1 KFP04928.1 - 0.00058 19.4 0.0 3.4 7.2 0.0 5.6 6 0 0 6 6 6 1 PapC N-terminal domain BatD PF13584.1 KFP04928.1 - 0.00062 18.4 2.9 0.44 9.0 0.0 4.5 6 0 0 6 6 6 2 Oxygen tolerance YtkA PF13115.1 KFP04928.1 - 0.001 19.3 16.9 1.7 9.0 0.1 10.8 14 0 0 14 14 14 1 YtkA-like EMP24_GP25L PF01105.19 KFP04928.1 - 0.0011 18.7 0.0 47 3.6 0.0 6.9 8 0 0 8 8 8 0 emp24/gp25L/p24 family/GOLD Exo_endo_phos PF03372.18 KFP04929.1 - 9.9e-15 55.1 0.0 1.2e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFP04929.1 - 9.6e-05 21.9 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Abhydrolase_6 PF12697.2 KFP04930.1 - 9.3e-38 130.3 0.0 1.3e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP04930.1 - 1.2e-17 63.9 0.0 2.9e-16 59.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP04930.1 - 2.2e-17 63.4 0.0 1.5e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.9 KFP04930.1 - 8.2e-06 24.5 0.0 3.6e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Ndr family DUF1057 PF06342.7 KFP04930.1 - 0.0022 16.8 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) UPF0227 PF05728.7 KFP04930.1 - 0.007 16.1 0.2 2.9 7.5 0.0 2.4 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 KFP04930.1 - 0.015 14.7 0.1 1.9 7.8 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Lipase PF00151.14 KFP04930.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipase Thioesterase PF00975.15 KFP04930.1 - 0.018 15.2 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.13 KFP04930.1 - 0.031 13.5 0.0 0.51 9.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.4 KFP04930.1 - 0.035 12.9 0.0 0.38 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Ser_hydrolase PF06821.8 KFP04930.1 - 0.086 12.4 0.0 8.4 5.9 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_3 PF07859.8 KFP04930.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold IPK PF03770.11 KFP04931.1 - 1.8e-64 217.0 0.6 1.8e-64 217.0 0.4 1.6 2 0 0 2 2 2 1 Inositol polyphosphate kinase DUF2013 PF09431.5 KFP04932.1 - 1.1e-38 132.1 0.5 2.6e-38 130.9 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Cadherin PF00028.12 KFP04933.1 - 6.4e-142 462.2 17.8 5.9e-22 77.7 0.1 8.5 8 0 0 8 8 8 8 Cadherin domain Sulfate_transp PF00916.15 KFP04933.1 - 1.1e-71 241.1 14.0 1.1e-71 241.1 9.7 2.5 3 0 0 3 3 3 1 Sulfate transporter family 7tm_2 PF00002.19 KFP04933.1 - 6.7e-50 169.4 16.4 6.7e-50 169.4 11.4 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Laminin_G_2 PF02210.19 KFP04933.1 - 1.4e-48 164.1 3.3 3.5e-32 111.1 0.0 3.5 3 0 0 3 3 3 2 Laminin G domain DUF3497 PF12003.3 KFP04933.1 - 1e-44 152.5 0.0 1.7e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) Laminin_G_1 PF00054.18 KFP04933.1 - 2.2e-27 95.6 0.1 1.9e-18 66.7 0.0 3.8 3 1 0 3 3 3 2 Laminin G domain Sulfate_tra_GLY PF13792.1 KFP04933.1 - 3.9e-27 93.7 1.3 2.3e-26 91.2 0.9 2.4 1 1 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFP04933.1 - 2.1e-22 78.7 0.2 5.4e-22 77.4 0.0 1.8 2 0 0 2 2 2 1 STAS domain EGF PF00008.22 KFP04933.1 - 3.4e-20 71.6 102.5 1.5e-07 31.2 5.0 9.1 9 1 0 9 9 9 6 EGF-like domain GPS PF01825.16 KFP04933.1 - 4.9e-09 36.1 4.3 3.2e-08 33.5 3.0 2.6 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain Laminin_EGF PF00053.19 KFP04933.1 - 3.8e-08 33.1 13.0 3.8e-08 33.1 9.0 8.3 6 2 2 8 8 8 2 Laminin EGF-like (Domains III and V) Peptidase_M16 PF00675.15 KFP04934.1 - 1.5e-50 170.8 0.0 2.3e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFP04934.1 - 4e-38 130.9 0.0 1.5e-37 129.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Vps39_1 PF10366.4 KFP04934.1 - 0.13 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Adaptin_N PF01602.15 KFP04935.1 - 2.3e-133 445.3 10.4 2.8e-133 445.0 7.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFP04935.1 - 1.7e-39 135.0 0.1 5e-39 133.5 0.1 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFP04935.1 - 3.3e-15 56.1 1.0 0.004 17.3 0.0 6.6 1 1 4 6 6 6 3 HEAT repeats HEAT PF02985.17 KFP04935.1 - 7e-08 31.9 5.0 3.4 7.9 0.0 7.5 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 KFP04935.1 - 3.7e-06 27.2 2.2 0.011 16.2 0.0 3.7 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 KFP04935.1 - 0.0015 18.3 9.3 0.97 9.2 0.0 4.3 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF4381 PF14316.1 KFP04935.1 - 0.0052 16.9 0.0 3.4 7.7 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4381) HEAT_PBS PF03130.11 KFP04935.1 - 0.058 13.8 1.4 23 5.8 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 KFP04935.1 - 0.09 12.6 0.0 11 6.0 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.1 KFP04935.1 - 0.1 11.5 1.0 1 8.3 0.0 2.7 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain DUF159 PF02586.9 KFP04936.1 - 9.2e-49 165.7 0.1 1.6e-48 165.0 0.0 1.4 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 Linker_histone PF00538.14 KFP04937.1 - 5.3e-06 26.4 0.1 5.3e-06 26.4 0.1 1.7 1 1 1 2 2 2 1 linker histone H1 and H5 family DUF2572 PF10833.3 KFP04937.1 - 0.078 12.3 0.3 0.09 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) 4F5 PF04419.9 KFP04937.1 - 8.7 7.1 10.6 2.1 9.1 4.8 1.8 1 1 1 2 2 2 0 4F5 protein family Ras PF00071.17 KFP04938.1 - 1.6e-58 196.6 0.1 1.9e-58 196.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP04938.1 - 6.8e-19 68.5 0.0 1.2e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP04938.1 - 2.1e-13 49.8 0.1 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP04938.1 - 2e-07 30.9 0.0 3.7e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP04938.1 - 5.3e-07 29.0 0.0 6.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP04938.1 - 1.6e-06 27.7 0.0 4.6e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFP04938.1 - 0.00029 20.9 0.0 0.00058 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFP04938.1 - 0.00092 18.4 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 KFP04938.1 - 0.0012 17.9 0.3 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Septin NTPase_1 PF03266.10 KFP04938.1 - 0.0027 17.4 0.1 0.0051 16.5 0.0 1.5 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.4 KFP04938.1 - 0.0035 16.8 0.1 0.088 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KFP04938.1 - 0.0038 16.6 0.1 0.016 14.6 0.0 1.9 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KFP04938.1 - 0.0042 16.6 0.4 0.15 11.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KFP04938.1 - 0.0052 16.5 0.5 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 KFP04938.1 - 0.0052 16.3 0.1 0.0097 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP04938.1 - 0.0074 16.2 0.1 0.037 14.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KFP04938.1 - 0.01 15.5 0.1 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KFP04938.1 - 0.011 15.3 0.0 0.035 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 KFP04938.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 KFP04938.1 - 0.018 14.4 0.2 0.028 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain NACHT PF05729.7 KFP04938.1 - 0.058 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KFP04938.1 - 0.074 12.9 0.2 0.15 11.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KFP04938.1 - 0.15 12.4 0.1 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Ribophorin_I PF04597.9 KFP04939.1 - 2e-136 454.9 6.8 2.7e-136 454.5 4.7 1.2 1 0 0 1 1 1 1 Ribophorin I DNA_repr_REX1B PF14966.1 KFP04939.1 - 0.0021 18.3 0.2 0.005 17.1 0.2 1.6 1 0 0 1 1 1 1 DNA repair REX1-B FliD_C PF07195.7 KFP04939.1 - 0.0092 15.2 0.5 0.015 14.5 0.3 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus OmpH PF03938.9 KFP04939.1 - 0.024 14.5 0.5 0.037 13.9 0.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.13 KFP04939.1 - 0.26 11.0 2.9 0.18 11.5 0.4 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 KFP04939.1 - 0.36 10.4 3.8 0.6 9.6 2.6 1.3 1 0 0 1 1 1 0 IncA protein GATA PF00320.22 KFP04940.1 - 4.2e-31 105.9 19.3 1.4e-15 56.3 4.3 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFP04940.1 - 0.00092 18.4 9.9 0.11 11.8 0.3 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Prim_Zn_Ribbon PF08273.7 KFP04940.1 - 0.71 9.9 12.9 0.079 13.0 1.3 2.8 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2387 PF09526.5 KFP04940.1 - 1.2 9.0 9.5 11 6.0 1.4 3.2 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) eIF-5_eIF-2B PF01873.12 KFP04940.1 - 1.4 8.6 7.6 11 5.7 1.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.2 KFP04940.1 - 4.4 7.2 13.2 1.3e+02 2.4 8.5 2.8 1 1 1 2 2 2 0 Double zinc ribbon GTP_EFTU PF00009.22 KFP04941.1 - 5.6e-17 61.7 0.0 1.3e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KFP04941.1 - 4.2e-09 36.4 0.1 9.6e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.14 KFP04941.1 - 9.8e-05 21.8 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D4 PF14578.1 KFP04941.1 - 0.0014 18.1 0.0 0.0047 16.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 TIP49 PF06068.8 KFP04942.1 - 4.2e-178 592.1 0.7 4.9e-178 591.8 0.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KFP04942.1 - 4e-13 49.7 0.3 2.4e-08 34.2 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFP04942.1 - 4.1e-11 42.3 2.9 2e-05 23.7 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFP04942.1 - 9.3e-07 29.0 0.0 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFP04942.1 - 1.6e-06 28.2 0.1 0.03 14.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFP04942.1 - 1.3e-05 24.8 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KFP04942.1 - 3.5e-05 23.5 0.0 0.0029 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KFP04942.1 - 4.5e-05 22.9 0.0 0.00012 21.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFP04942.1 - 0.0003 20.3 0.1 0.26 10.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 KFP04942.1 - 0.00052 19.4 0.1 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KFP04942.1 - 0.00065 18.8 0.6 0.0013 17.8 0.2 1.6 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 KFP04942.1 - 0.0012 18.0 0.1 0.071 12.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFP04942.1 - 0.0013 19.0 0.8 0.015 15.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KFP04942.1 - 0.0014 19.4 0.0 0.0036 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFP04942.1 - 0.0015 18.4 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFP04942.1 - 0.0034 17.2 0.0 0.0094 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KFP04942.1 - 0.0059 15.8 0.1 0.018 14.2 0.1 1.8 1 0 0 1 1 1 1 PhoH-like protein DnaB_C PF03796.10 KFP04942.1 - 0.0067 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_14 PF13173.1 KFP04942.1 - 0.0092 15.8 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFP04942.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 KFP04942.1 - 0.015 14.9 0.0 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KFP04942.1 - 0.02 14.5 0.1 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KFP04942.1 - 0.023 13.7 1.0 0.15 11.1 0.0 2.5 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.4 KFP04942.1 - 0.026 13.4 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KFP04942.1 - 0.033 13.8 0.2 0.086 12.5 0.0 1.8 2 0 0 2 2 1 0 NTPase DNA_pol3_delta2 PF13177.1 KFP04942.1 - 0.04 13.5 0.0 0.59 9.7 0.0 2.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit ResIII PF04851.10 KFP04942.1 - 0.046 13.5 0.2 0.68 9.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KFP04942.1 - 0.057 12.2 0.1 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 KFP04942.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KFP04942.1 - 0.12 12.4 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain SecY PF00344.15 KFP04943.1 - 2.5e-96 322.6 13.7 3.5e-96 322.1 9.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KFP04943.1 - 1.4e-19 69.2 0.3 4.2e-19 67.7 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Phage_holin_1 PF04531.8 KFP04943.1 - 0.035 14.1 0.1 3.3 7.8 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin YlaH PF14036.1 KFP04943.1 - 0.035 14.1 3.1 0.46 10.5 0.1 3.1 3 0 0 3 3 3 0 YlaH-like protein Kelch_1 PF01344.20 KFP04944.1 - 1.4e-31 107.7 3.8 1.8e-11 43.4 0.0 4.9 4 1 0 4 4 4 4 Kelch motif BACK PF07707.10 KFP04944.1 - 1.5e-29 101.8 5.8 1.8e-29 101.6 0.8 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.1 KFP04944.1 - 2e-28 97.3 2.7 4.1e-09 36.2 0.0 5.6 3 1 3 6 6 6 4 Kelch motif BTB PF00651.26 KFP04944.1 - 5.2e-24 84.3 2.9 5.2e-24 84.3 2.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFP04944.1 - 1.6e-16 59.7 0.4 2.8e-05 23.8 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP04944.1 - 7.3e-16 57.2 4.8 1.3e-07 31.0 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 KFP04944.1 - 2.9e-13 49.5 3.1 0.00034 20.6 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP04944.1 - 4.6e-11 42.4 0.7 0.00015 21.5 0.0 4.3 4 0 0 4 4 4 2 Kelch motif DUF3342 PF11822.3 KFP04944.1 - 1.6e-05 24.2 1.8 1.6e-05 24.2 1.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) Trypsin PF00089.21 KFP04945.1 - 1.6e-59 201.1 0.6 1.7e-59 201.0 0.4 1.0 1 0 0 1 1 1 1 Trypsin C1-set PF07654.10 KFP04946.1 - 4.4e-15 55.4 0.0 5.7e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Immunoglobulin C1-set domain V-set PF07686.12 KFP04947.1 - 6.2e-15 55.0 0.1 7.4e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP04947.1 - 0.00014 21.8 0.1 0.00017 21.6 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP04947.1 - 0.0083 16.6 0.4 0.02 15.4 0.3 1.5 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP04947.1 - 0.031 14.3 0.0 0.074 13.1 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin domain Pkinase_Tyr PF07714.12 KFP04948.1 - 3e-94 314.9 0.0 4.2e-94 314.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFP04948.1 - 1.6e-74 249.5 0.2 2.4e-74 248.9 0.1 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFP04948.1 - 4.1e-46 157.2 0.0 5.7e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFP04948.1 - 3.5e-25 87.9 0.8 2.4e-14 53.2 0.1 3.2 3 0 0 3 3 3 2 Fibronectin type III domain SAM_1 PF00536.25 KFP04948.1 - 1.4e-20 73.1 0.1 2.9e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP04948.1 - 1.7e-20 72.6 0.0 3.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 KFP04948.1 - 1.6e-19 70.0 0.0 2.9e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain GCC2_GCC3 PF07699.8 KFP04948.1 - 1.4e-06 27.7 1.2 1.4e-06 27.7 0.9 2.4 2 1 1 3 3 3 1 GCC2 and GCC3 cEGF PF12662.2 KFP04948.1 - 0.0064 16.1 0.7 0.023 14.3 0.5 2.0 1 0 0 1 1 1 1 Complement Clr-like EGF-like Interfer-bind PF09294.5 KFP04948.1 - 0.028 14.4 0.0 1 9.4 0.0 3.0 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III EGF_CA PF07645.10 KFP04948.1 - 3.2 7.8 8.4 10 6.2 0.4 2.7 2 0 0 2 2 2 0 Calcium-binding EGF domain Ank_2 PF12796.2 KFP04949.1 - 1.2e-24 86.4 5.4 1.8e-13 50.6 2.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP04949.1 - 1.4e-19 70.0 0.9 5.5e-05 23.5 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP04949.1 - 3.6e-19 66.9 4.6 3.1e-05 23.8 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.25 KFP04949.1 - 4.5e-19 67.2 3.6 4.1e-05 23.1 0.1 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KFP04949.1 - 2.8e-16 59.1 4.7 0.00047 20.3 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ion_trans PF00520.26 KFP04949.1 - 2.5e-06 26.8 14.2 2.5e-06 26.8 9.9 3.0 2 1 1 3 3 3 1 Ion transport protein OKR_DC_1 PF01276.15 KFP04949.1 - 0.07 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DSBA PF01323.15 KFP04950.1 - 5.7e-36 123.8 0.0 6.8e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Rap_GAP PF02145.10 KFP04951.1 - 9.1e-63 211.0 0.0 1.4e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP GoLoco PF02188.12 KFP04951.1 - 0.00016 20.9 1.3 0.00032 19.9 0.9 1.6 1 0 0 1 1 1 1 GoLoco motif DUF3729 PF12526.3 KFP04952.1 - 0.091 14.1 2.0 0.098 14.0 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3729) Myc_target_1 PF15179.1 KFP04952.1 - 0.25 10.9 2.2 0.36 10.3 1.6 1.6 1 1 0 1 1 1 0 Myc target protein 1 TMEM51 PF15345.1 KFP04952.1 - 0.39 10.3 4.2 0.39 10.3 2.5 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 Peptidase_C14 PF00656.17 KFP04953.1 - 8.7e-37 127.1 1.1 1.3e-36 126.5 0.3 1.5 2 0 0 2 2 2 1 Caspase domain CARD PF00619.16 KFP04953.1 - 6.5e-19 67.5 0.2 2e-18 65.9 0.3 1.7 2 0 0 2 2 2 1 Caspase recruitment domain Yae1_N PF09811.4 KFP04954.1 - 3.7e-13 48.7 34.8 26 4.4 24.1 3.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal FAM131 PF15010.1 KFP04955.1 - 3e-115 385.0 12.1 3.8e-115 384.6 8.4 1.1 1 0 0 1 1 1 1 Putative cell signalling DUF240 PF03086.9 KFP04955.1 - 0.059 13.0 1.0 0.1 12.2 0.7 1.5 1 1 0 1 1 1 0 MG032/MG096/MG288 family 2 LIM PF00412.17 KFP04956.1 - 9e-34 115.3 33.9 9.7e-13 47.9 5.9 3.2 3 0 0 3 3 3 3 LIM domain Pkinase_Tyr PF07714.12 KFP04957.1 - 2.3e-96 321.8 0.0 3.7e-96 321.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFP04957.1 - 1.6e-57 194.1 0.9 2.5e-57 193.5 0.6 1.3 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFP04957.1 - 1.8e-48 164.9 0.0 2.6e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.25 KFP04957.1 - 2.3e-22 78.9 0.0 4.6e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) fn3 PF00041.16 KFP04957.1 - 2.4e-22 78.8 0.0 7.4e-10 38.8 0.0 2.8 3 0 0 3 3 2 2 Fibronectin type III domain SAM_2 PF07647.12 KFP04957.1 - 5.2e-18 64.6 0.0 1.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EphA2_TM PF14575.1 KFP04957.1 - 6.7e-13 48.8 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain GCC2_GCC3 PF07699.8 KFP04957.1 - 2.4e-05 23.8 2.5 2.4e-05 23.8 1.7 3.1 2 1 1 3 3 3 1 GCC2 and GCC3 Tissue_fac PF01108.12 KFP04957.1 - 0.0021 17.7 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 1 Tissue factor SusE PF14292.1 KFP04957.1 - 0.04 13.7 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 SusE outer membrane protein Reeler PF02014.11 KFP04957.1 - 0.046 13.9 0.1 25 5.0 0.0 3.0 3 0 0 3 3 3 0 Reeler domain Kdo PF06293.9 KFP04957.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SUKH-3 PF14433.1 KFP04957.1 - 0.14 11.9 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 SUKH-3 immunity protein PMP1_2 PF08114.6 KFP04957.1 - 0.57 9.7 3.1 7.3 6.1 1.4 2.5 2 0 0 2 2 2 0 ATPase proteolipid family NCD3G PF07562.9 KFP04957.1 - 6.1 6.6 13.3 0.056 13.1 2.0 2.7 2 1 1 3 3 2 0 Nine Cysteines Domain of family 3 GPCR 7tm_4 PF13853.1 KFP04958.1 - 1e-36 125.9 11.5 1e-36 125.9 8.0 2.8 2 1 1 3 3 3 1 Olfactory receptor 7tm_1 PF00001.16 KFP04958.1 - 3.5e-22 78.7 18.4 6.3e-22 77.9 12.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TPR_11 PF13414.1 KFP04959.1 - 9.6e-27 92.4 6.2 2.9e-13 49.2 0.1 4.7 2 2 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KFP04959.1 - 2.9e-24 83.6 1.5 2.7e-06 26.7 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFP04959.1 - 6.9e-20 69.3 5.9 0.00013 21.6 0.3 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFP04959.1 - 3.2e-18 64.3 0.5 0.0079 16.3 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFP04959.1 - 1.2e-16 60.8 13.1 5.5e-07 30.0 0.5 5.8 4 2 4 8 8 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFP04959.1 - 5.3e-15 54.5 19.8 0.0072 16.8 0.1 8.3 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFP04959.1 - 2.2e-11 42.6 0.1 0.3 10.9 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFP04959.1 - 3e-11 43.1 4.3 1.1e-06 28.4 0.9 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP04959.1 - 3.9e-11 43.1 3.9 0.013 15.7 0.0 4.9 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFP04959.1 - 1.4e-10 40.1 1.6 0.12 12.2 0.0 6.2 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KFP04959.1 - 4.5e-08 33.1 1.7 0.0013 18.7 0.0 3.0 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KFP04959.1 - 7e-08 32.4 1.9 0.1 12.7 0.1 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFP04959.1 - 6.9e-07 29.0 2.5 0.21 11.5 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP04959.1 - 9.5e-07 28.5 5.9 0.038 13.8 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP04959.1 - 0.00052 20.3 9.3 3.4 8.3 0.1 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF1641 PF07849.6 KFP04959.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Secretin_N_2 PF07655.8 KFP04959.1 - 0.1 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Imm15 PF15590.1 KFP04959.1 - 4.4 6.4 7.6 8.9 5.4 0.1 3.2 2 1 1 3 3 3 0 Immunity protein 15 Mito_carr PF00153.22 KFP04960.1 - 7.8e-67 221.0 0.0 1.4e-22 79.1 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Lipocalin_7 PF14651.1 KFP04961.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family CUB PF00431.15 KFP04962.1 - 1.3e-50 170.0 0.1 7e-27 93.6 0.0 2.4 2 0 0 2 2 2 2 CUB domain Trypsin PF00089.21 KFP04962.1 - 4.6e-50 170.2 0.0 7.1e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sushi PF00084.15 KFP04962.1 - 7e-14 51.9 16.7 4.3e-09 36.5 1.1 3.6 3 0 0 3 3 3 2 Sushi domain (SCR repeat) FXa_inhibition PF14670.1 KFP04962.1 - 2.8e-10 40.1 8.4 1e-09 38.3 4.4 2.8 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFP04962.1 - 8.4e-05 22.4 8.7 0.00011 22.0 4.2 2.7 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.2 KFP04962.1 - 0.00025 20.6 4.4 0.0015 18.0 1.6 3.0 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.22 KFP04962.1 - 0.00058 19.7 4.3 0.0024 17.7 3.0 2.2 1 0 0 1 1 1 1 EGF-like domain CUB_2 PF02408.15 KFP04962.1 - 0.0069 15.9 0.2 1.3 8.5 0.0 3.0 3 0 0 3 3 3 1 CUB-like domain Peptidase_S6 PF02395.11 KFP04962.1 - 0.031 12.4 0.2 0.047 11.8 0.2 1.2 1 0 0 1 1 1 0 Immunoglobulin A1 protease Trypsin PF00089.21 KFP04963.1 - 5e-33 114.5 0.0 5.5e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Trypsin CUB PF00431.15 KFP04964.1 - 8.5e-19 67.6 1.0 2e-18 66.4 0.1 1.9 2 0 0 2 2 2 1 CUB domain FXa_inhibition PF14670.1 KFP04964.1 - 2.2e-09 37.2 6.5 4.2e-09 36.3 4.5 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFP04964.1 - 2.5e-06 27.3 9.0 4.9e-06 26.4 6.2 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF PF00008.22 KFP04964.1 - 0.0001 22.2 8.8 0.0002 21.2 6.1 1.5 1 0 0 1 1 1 1 EGF-like domain CUB_2 PF02408.15 KFP04964.1 - 0.03 13.8 1.0 0.076 12.5 0.7 2.0 1 1 0 1 1 1 0 CUB-like domain MBOAT PF03062.14 KFP04965.1 - 2.1e-52 178.2 9.3 2.1e-52 178.2 6.4 2.5 2 1 1 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family EMG1 PF03587.9 KFP04966.1 - 8.9e-61 204.7 0.0 1e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Band_7 PF01145.20 KFP04967.1 - 3.8e-17 62.7 5.1 3.8e-17 62.7 3.5 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family Med2 PF11214.3 KFP04967.1 - 0.00093 19.2 2.0 0.0017 18.3 1.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 FYVE_2 PF02318.11 KFP04967.1 - 0.094 12.6 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger ATP-synt_E PF05680.7 KFP04967.1 - 0.32 10.9 3.9 0.74 9.8 2.7 1.6 1 0 0 1 1 1 0 ATP synthase E chain Y_phosphatase PF00102.22 KFP04968.1 - 2.3e-79 266.0 0.2 3.8e-79 265.3 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SH2 PF00017.19 KFP04968.1 - 1.5e-46 156.0 0.0 2.8e-22 78.3 0.0 2.8 2 0 0 2 2 2 2 SH2 domain DSPc PF00782.15 KFP04968.1 - 7e-06 25.6 0.1 2.7e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFP04968.1 - 0.002 18.1 0.1 0.0091 16.0 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFP04968.1 - 0.0055 16.9 0.9 0.029 14.6 0.0 2.7 4 0 0 4 4 4 1 Tyrosine phosphatase family Methyltransf_2 PF00891.13 KFP04968.1 - 0.15 11.2 0.3 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase Enolase_C PF00113.17 KFP04969.1 - 2e-160 532.6 0.0 2.5e-160 532.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFP04969.1 - 4.6e-58 194.8 0.0 7.3e-58 194.1 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KFP04969.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KFP04969.1 - 3.4e-05 22.8 0.3 7.5e-05 21.7 0.2 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KFP04969.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain LRR_4 PF12799.2 KFP04970.1 - 2.1e-26 91.0 33.9 1.5e-07 30.9 0.2 6.3 2 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP04970.1 - 4.2e-24 84.0 67.7 7.6e-09 35.1 1.9 5.1 1 1 7 8 8 8 8 Leucine rich repeat LRR_9 PF14580.1 KFP04970.1 - 4.3e-13 49.2 7.6 8.7e-13 48.2 1.6 2.4 1 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.28 KFP04970.1 - 4.7e-10 38.0 22.3 0.088 12.8 0.3 8.1 5 3 2 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 KFP04970.1 - 5.7e-07 28.7 25.2 1.2 9.6 0.2 9.5 10 0 0 10 10 10 3 Leucine rich repeat LRR_6 PF13516.1 KFP04970.1 - 0.00062 19.5 28.6 1.7 8.9 0.2 8.9 7 3 3 10 10 10 4 Leucine Rich repeat LRR_3 PF07725.7 KFP04970.1 - 1.9 8.4 14.7 9.8 6.1 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat TIM PF00121.13 KFP04971.1 - 9.2e-88 293.4 0.2 1e-87 293.2 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase WD40 PF00400.27 KFP04972.1 - 4.9e-55 181.5 23.3 1.1e-09 37.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFP04972.1 - 5.3e-08 32.8 0.0 0.0068 16.1 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A UL11 PF11094.3 KFP04972.1 - 0.015 15.0 0.5 0.045 13.5 0.3 1.8 1 0 0 1 1 1 0 Membrane-associated tegument protein Cytochrom_D1 PF02239.11 KFP04972.1 - 0.034 12.4 0.0 0.31 9.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Pox_A_type_inc PF04508.7 KFP04972.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat 2OG-FeII_Oxy_3 PF13640.1 KFP04973.1 - 3.1e-15 56.5 0.0 9.4e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFP04973.1 - 0.008 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFP04973.1 - 0.011 15.3 0.1 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_6 PF13174.1 KFP04973.1 - 0.77 10.3 4.3 2.2 8.9 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFP04973.1 - 2.2 7.9 7.9 12 5.5 0.2 3.4 3 0 0 3 3 3 0 TPR repeat V-set PF07686.12 KFP04974.1 - 3.9e-12 46.0 2.4 0.034 14.0 0.2 4.3 4 0 0 4 4 4 3 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP04974.1 - 2.6e-11 43.4 3.0 0.03 14.4 0.0 4.6 3 1 1 4 4 4 4 Immunoglobulin domain ig PF00047.20 KFP04974.1 - 1.9e-07 31.1 0.4 1.2 9.3 0.0 4.8 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.11 KFP04974.1 - 1.9e-07 30.8 0.5 0.49 10.2 0.0 4.5 4 2 1 5 5 5 3 Immunoglobulin I-set domain Tcell_CD4_Cterm PF12104.3 KFP04974.1 - 8.8e-07 28.3 12.2 1.5e-06 27.6 8.4 1.4 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region Ig_3 PF13927.1 KFP04974.1 - 1.7e-05 25.2 4.2 4.2 7.9 0.1 4.9 3 2 1 4 4 4 2 Immunoglobulin domain C2-set PF05790.10 KFP04974.1 - 0.0014 18.5 1.0 0.55 10.2 0.0 3.5 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Filamin PF00630.14 KFP04974.1 - 0.0095 16.4 0.8 2.5 8.7 0.1 3.4 3 1 0 3 3 3 1 Filamin/ABP280 repeat CD4-extracel PF09191.5 KFP04974.1 - 0.013 15.4 0.2 0.033 14.2 0.1 1.7 1 0 0 1 1 1 0 CD4, extracellular Ig_2 PF13895.1 KFP04975.1 - 1.9e-10 40.7 0.2 2.4e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP04975.1 - 8.8e-09 35.1 0.0 0.00016 21.4 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFP04975.1 - 1.6e-08 34.5 0.0 0.0001 22.3 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP04975.1 - 7e-07 29.1 0.4 0.02 14.7 0.0 2.9 1 1 1 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP04975.1 - 1.1e-06 29.0 0.2 0.0015 18.9 0.2 2.4 2 0 0 2 2 2 2 Immunoglobulin domain Receptor_2B4 PF11465.3 KFP04975.1 - 0.00074 19.4 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 Natural killer cell receptor 2B4 Mlf1IP PF10248.4 KFP04977.1 - 2.5e-76 255.1 6.3 3.1e-76 254.8 4.4 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein PCI PF01399.22 KFP04978.1 - 1.8e-11 44.2 0.3 5.5e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 PCI domain Sipho_Gp157 PF05565.6 KFP04978.1 - 0.02 14.5 0.2 0.03 13.8 0.2 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Rtf2 PF04641.7 KFP04978.1 - 0.092 11.9 2.1 0.12 11.5 1.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger AJAP1_PANP_C PF15298.1 KFP04979.1 - 7.1e-62 208.9 0.0 8.6e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Shisa PF13908.1 KFP04979.1 - 0.052 13.7 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 KFP04979.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 IncA protein zf-H2C2_2 PF13465.1 KFP04980.1 - 2.5e-25 87.4 51.4 3.2e-06 27.1 0.1 8.1 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFP04980.1 - 6.2e-21 73.4 54.1 2e-05 24.6 2.2 7.5 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP04980.1 - 1.5e-11 43.8 53.9 0.0003 20.9 1.9 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP04980.1 - 4.8e-05 23.0 35.8 0.057 13.3 0.5 6.9 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFP04980.1 - 0.0038 16.8 1.0 0.0038 16.8 0.7 4.6 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KFP04980.1 - 0.018 15.1 36.3 0.021 14.9 0.3 6.7 6 1 1 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP04980.1 - 0.11 12.7 40.3 0.073 13.3 1.5 6.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP04980.1 - 0.18 11.9 35.3 0.12 12.4 3.1 4.5 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 KFP04980.1 - 1.3 9.0 10.7 11 6.0 0.1 4.1 3 1 0 3 3 3 0 zinc-finger zf-trcl PF13451.1 KFP04980.1 - 8.6 6.0 10.5 11 5.7 0.4 3.6 3 0 0 3 3 3 0 Probable zinc-binding domain ING PF12998.2 KFP04981.1 - 3.9e-27 94.5 2.2 3.9e-27 94.5 1.5 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFP04981.1 - 4.7e-10 38.9 7.8 8.5e-10 38.1 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KFP04981.1 - 0.016 15.3 0.5 0.038 14.1 0.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 KFP04981.1 - 0.02 14.1 1.3 0.035 13.4 0.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KFP04981.1 - 0.037 14.0 5.2 0.064 13.2 3.6 1.4 1 0 0 1 1 1 0 RING-like domain HCMV_UL139 PF12507.3 KFP04981.1 - 0.047 13.8 0.3 0.11 12.6 0.2 1.7 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein ORF6C PF10552.4 KFP04981.1 - 0.78 9.4 6.9 2.9 7.6 1.3 2.2 2 0 0 2 2 2 0 ORF6C domain RNase_H2-Ydr279 PF09468.5 KFP04981.1 - 1.3 8.1 7.9 1.6 7.8 5.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LMBR1 PF04791.11 KFP04981.1 - 6.1 5.3 6.2 7 5.1 3.7 1.4 1 1 1 2 2 2 0 LMBR1-like membrane protein PBP_sp32 PF07222.7 KFP04982.1 - 1.2e-38 132.7 4.9 1.7e-36 125.6 0.1 2.4 2 0 0 2 2 2 2 Proacrosin binding protein sp32 Kazal_2 PF07648.10 KFP04982.1 - 0.0027 17.5 1.1 0.0027 17.5 0.8 3.8 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.16 KFP04983.1 - 1e-50 172.2 23.7 1.2e-50 172.0 16.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF983 PF06170.7 KFP04983.1 - 0.1 12.7 0.4 0.1 12.7 0.3 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF983) DUF3302 PF11742.3 KFP04983.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) Git3_C PF11970.3 KFP04983.1 - 1.5 8.6 9.3 0.11 12.2 0.3 3.3 2 1 2 4 4 4 0 G protein-coupled glucose receptor regulating Gpa2 C-term CHDCT2 PF08074.6 KFP04984.1 - 1.2e-95 318.0 0.5 3.2e-95 316.7 0.3 1.8 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain DUF1086 PF06461.6 KFP04984.1 - 6.1e-70 233.6 0.0 1.3e-69 232.5 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) SNF2_N PF00176.18 KFP04984.1 - 8.3e-67 225.0 0.0 1.5e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain CHDNT PF08073.7 KFP04984.1 - 2.5e-31 107.1 0.2 5.9e-31 105.9 0.1 1.7 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1087 PF06465.8 KFP04984.1 - 1.7e-26 91.8 7.0 1.7e-26 91.8 4.9 2.5 2 0 0 2 2 1 1 Domain of Unknown Function (DUF1087) PHD PF00628.24 KFP04984.1 - 5.1e-22 77.3 28.0 4.6e-11 42.2 6.3 2.5 2 0 0 2 2 2 2 PHD-finger Chromo PF00385.19 KFP04984.1 - 7.6e-20 70.3 5.4 5.7e-13 48.3 0.4 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFP04984.1 - 1e-17 63.7 0.0 2.5e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFP04984.1 - 2.9e-10 39.4 0.0 1.2e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFP04984.1 - 2.2e-06 27.6 0.7 1.4e-05 25.0 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PHD_2 PF13831.1 KFP04984.1 - 0.00015 20.9 11.2 0.025 13.8 1.9 2.6 2 0 0 2 2 2 2 PHD-finger AAA_22 PF13401.1 KFP04984.1 - 0.078 13.1 0.0 0.27 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain C1_1 PF00130.17 KFP04984.1 - 0.95 9.2 18.4 0.32 10.7 0.8 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFP04984.1 - 3.9 7.2 19.5 2.4 7.9 2.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Filament PF00038.16 KFP04985.1 - 4.2e-15 56.0 27.3 8.6e-11 41.8 1.5 2.8 3 0 0 3 3 3 2 Intermediate filament protein Snapin_Pallidin PF14712.1 KFP04985.1 - 0.0052 17.0 2.6 0.0052 17.0 1.8 2.6 3 0 0 3 3 3 1 Snapin/Pallidin PAPA-1 PF04795.7 KFP04985.1 - 0.12 13.0 0.0 0.12 13.0 0.0 3.8 3 2 2 5 5 5 0 PAPA-1-like conserved region Sds3 PF08598.6 KFP04985.1 - 2.4 7.6 16.8 1.4 8.4 3.3 2.5 1 1 1 2 2 2 0 Sds3-like DUF4097 PF13349.1 KFP04985.1 - 3 7.3 5.1 2.8 7.4 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4097) CENP-F_leu_zip PF10473.4 KFP04985.1 - 3.1 7.6 28.0 0.025 14.4 3.4 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.8 KFP04985.1 - 8.9 6.7 10.5 1 9.7 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Gp_dh_C PF02800.15 KFP04986.1 - 3.6e-72 240.9 0.0 5.8e-72 240.2 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFP04986.1 - 9.7e-56 187.9 0.1 1.9e-55 187.0 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA PF03968.9 KFP04986.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 OstA-like protein MRP-L51 PF10244.4 KFP04987.1 - 4.9e-43 145.0 1.6 5.7e-43 144.8 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit Synaptobrevin PF00957.16 KFP04988.1 - 3.4e-30 103.4 1.1 3.6e-30 103.4 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF912 PF06024.7 KFP04988.1 - 0.0062 16.5 0.1 0.0068 16.4 0.0 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Fijivirus_P9-2 PF06837.6 KFP04988.1 - 0.02 14.0 0.4 0.023 13.8 0.2 1.0 1 0 0 1 1 1 0 Fijivirus P9-2 protein Spore_III_AB PF09548.5 KFP04988.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Seryl_tRNA_N PF02403.17 KFP04988.1 - 0.13 12.3 0.2 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CD34_antigen PF06365.7 KFP04988.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family Ank_2 PF12796.2 KFP04989.1 - 2.2e-58 194.5 14.8 5.2e-18 65.1 0.2 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFP04989.1 - 2.5e-44 146.9 7.0 5.7e-07 29.0 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFP04989.1 - 3.1e-43 144.8 6.9 2.9e-09 36.8 0.1 6.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP04989.1 - 1e-36 121.2 4.2 9.3e-07 28.5 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFP04989.1 - 4.6e-36 122.5 5.1 2.2e-09 37.5 0.1 5.5 2 1 4 6 6 6 6 Ankyrin repeats (many copies) SAM_1 PF00536.25 KFP04989.1 - 3.8e-26 91.0 0.0 3.3e-15 56.0 0.0 2.9 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP04989.1 - 1.2e-22 79.5 1.0 3.2e-15 55.7 0.0 2.8 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) pRN1_helical PF13010.1 KFP04989.1 - 0.17 11.4 0.1 1.3 8.6 0.0 2.3 3 0 0 3 3 3 0 Primase helical domain PID PF00640.18 KFP04990.1 - 1.1e-31 109.6 0.4 1.4e-31 109.3 0.3 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFP04990.1 - 0.0021 17.9 0.2 0.006 16.4 0.1 1.7 1 1 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 KFP04990.1 - 0.049 13.2 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Coq4 PF05019.8 KFP04990.1 - 0.073 11.9 0.0 6.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 WD40 PF00400.27 KFP04991.1 - 1.6e-78 256.0 52.5 2.8e-10 39.6 0.1 14.1 14 0 0 14 14 14 11 WD domain, G-beta repeat NB-ARC PF00931.17 KFP04991.1 - 2.1e-65 220.4 0.0 3.7e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain CARD PF00619.16 KFP04991.1 - 1.3e-15 56.9 1.0 1.3e-15 56.9 0.7 2.0 2 0 0 2 2 2 1 Caspase recruitment domain AAA_16 PF13191.1 KFP04991.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFP04991.1 - 0.01 15.9 0.0 0.058 13.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain DUF2415 PF10313.4 KFP04991.1 - 0.046 13.3 0.4 0.58 9.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) MHC2-interact PF09307.5 KFP04992.1 - 0.00063 19.5 0.2 0.0042 16.8 0.0 2.4 2 0 0 2 2 2 1 CLIP, MHC2 interacting CAMP_factor PF07373.6 KFP04992.1 - 0.0033 16.9 8.0 0.01 15.3 3.3 2.3 2 0 0 2 2 2 1 CAMP factor (Cfa) Talin_middle PF09141.5 KFP04992.1 - 0.018 14.7 3.5 0.036 13.7 2.2 1.6 1 1 0 1 1 1 0 Talin, middle domain COG5 PF10392.4 KFP04992.1 - 0.029 14.3 13.5 0.71 9.8 2.7 3.6 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF148 PF02520.12 KFP04992.1 - 0.062 13.1 14.6 0.21 11.3 1.0 3.4 1 1 2 3 3 3 0 Domain of unknown function DUF148 NPV_P10 PF05531.7 KFP04992.1 - 0.15 12.3 16.3 0.98 9.7 3.8 4.2 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KFP04992.1 - 0.41 9.7 13.4 1.9 7.5 8.0 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 KFP04992.1 - 0.52 10.7 9.1 24 5.3 0.1 4.5 4 1 0 4 4 4 0 SlyX IncA PF04156.9 KFP04992.1 - 0.59 9.7 19.9 0.45 10.0 2.0 3.0 1 1 1 2 2 2 0 IncA protein UCH PF00443.24 KFP04992.1 - 0.65 9.0 4.8 5.4 6.0 3.1 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF948 PF06103.6 KFP04992.1 - 1.3 8.9 18.0 6.8 6.6 0.2 4.7 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF2400 PF09674.5 KFP04992.1 - 2.6 7.6 8.3 0.83 9.3 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Med9 PF07544.8 KFP04992.1 - 3.4 7.4 12.6 0.9 9.3 0.1 4.4 1 1 3 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.17 KFP04992.1 - 4.6 7.3 16.3 0.99 9.4 0.4 4.0 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Adeno_PIX PF03955.9 KFP04992.1 - 5.5 7.5 8.1 5.1 7.6 0.5 3.8 3 2 1 4 4 4 0 Adenovirus hexon-associated protein (IX) Vac_Fusion PF02346.11 KFP04992.1 - 7.8 6.0 7.8 4.7 6.7 0.1 4.1 4 1 1 5 5 5 0 Chordopoxvirus fusion protein Lectin_N PF03954.9 KFP04992.1 - 9 5.7 22.1 1 8.7 5.1 3.8 2 1 3 5 5 5 0 Hepatic lectin, N-terminal domain Mito_carr PF00153.22 KFP04993.1 - 9.5e-48 159.8 7.8 4.6e-20 71.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein LEM PF03020.10 KFP04994.1 - 6.4e-22 76.7 1.1 1.2e-21 75.8 0.8 1.5 1 0 0 1 1 1 1 LEM domain Spc24 PF08286.6 KFP04995.1 - 0.1 12.2 0.7 7.5 6.2 0.0 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Mod_r PF07200.8 KFP04995.1 - 0.23 11.3 1.8 0.37 10.6 1.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Pkinase PF00069.20 KFP04996.1 - 3.8e-74 249.0 0.0 7.9e-74 248.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP04996.1 - 5.6e-35 120.6 0.0 1.2e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP04996.1 - 3.9e-07 29.3 0.0 6.6e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP04996.1 - 0.0007 18.7 0.1 0.002 17.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFP04996.1 - 0.039 13.3 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KFP04996.1 - 0.046 12.5 0.0 0.088 11.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KFP04996.1 - 0.049 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ets PF00178.17 KFP04997.1 - 9.2e-38 128.2 3.5 1.4e-37 127.6 2.4 1.3 1 0 0 1 1 1 1 Ets-domain TPK_catalytic PF04263.11 KFP04999.1 - 4.2e-32 110.3 0.0 5e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Abhydrolase_6 PF12697.2 KFP05001.1 - 1.1e-35 123.6 0.0 1.5e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP05001.1 - 3.4e-21 75.8 0.2 8.5e-14 51.6 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFP05001.1 - 2.9e-19 69.2 0.1 1.4e-18 67.0 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFP05001.1 - 6e-07 29.2 0.2 4.2e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KFP05001.1 - 6e-05 22.5 0.4 0.23 10.8 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KFP05001.1 - 0.018 14.2 0.0 0.17 11.0 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KFP05001.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.8 KFP05001.1 - 0.02 14.3 0.0 0.059 12.7 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.13 KFP05001.1 - 0.021 14.1 0.0 3.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.20 KFP05001.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ndr PF03096.9 KFP05001.1 - 0.062 11.7 0.1 0.39 9.1 0.0 2.0 1 1 0 1 1 1 0 Ndr family Abhydrolase_8 PF06259.7 KFP05001.1 - 0.099 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Ser_hydrolase PF06821.8 KFP05001.1 - 0.14 11.7 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase BAAT_C PF08840.6 KFP05001.1 - 0.14 11.8 0.0 1.4 8.6 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hormone_recep PF00104.25 KFP05002.1 - 8.2e-40 136.1 0.0 1.1e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor CaMBD PF02888.11 KFP05004.1 - 3.4e-24 84.4 5.4 5.5e-24 83.7 3.8 1.3 1 0 0 1 1 1 1 Calmodulin binding domain SK_channel PF03530.9 KFP05004.1 - 2.7e-18 65.9 0.7 6.7e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 Calcium-activated SK potassium channel DUF1014 PF06244.7 KFP05005.1 - 1.6e-45 154.2 9.4 1.6e-45 154.2 6.5 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 KFP05005.1 - 0.004 17.4 0.6 0.004 17.4 0.4 2.9 3 1 1 4 4 4 1 HMG (high mobility group) box DUF4058 PF13267.1 KFP05005.1 - 0.12 11.4 4.2 0.1 11.7 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4058) HSP70 PF00012.15 KFP05005.1 - 6.4 4.5 16.7 8.9 4.0 11.6 1.2 1 0 0 1 1 1 0 Hsp70 protein SSF PF00474.12 KFP05006.1 - 1.3e-24 86.6 14.7 9.1e-13 47.6 4.3 2.1 1 1 1 2 2 2 2 Sodium:solute symporter family Ribosomal_L7Ae PF01248.21 KFP05008.1 - 5.8e-09 35.3 0.0 7.9e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family G-gamma PF00631.17 KFP05009.1 - 1e-18 66.8 0.0 1.1e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 GGL domain Zip PF02535.17 KFP05010.1 - 3.7e-54 183.8 7.5 5e-54 183.4 5.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.6 KFP05010.1 - 0.32 10.2 3.4 0.26 10.5 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TPR_1 PF00515.23 KFP05011.1 - 1.4e-27 94.1 5.9 2.9e-10 39.3 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFP05011.1 - 4.9e-25 86.9 8.3 5.6e-18 64.3 0.7 2.7 3 0 0 3 3 2 2 TPR repeat TPR_2 PF07719.12 KFP05011.1 - 3e-20 70.4 4.4 4e-06 26.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP05011.1 - 3.4e-15 54.9 3.0 9.4e-06 25.4 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFP05011.1 - 5.1e-14 50.9 3.3 7.4e-06 25.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFP05011.1 - 1.6e-13 50.9 2.2 8.2e-08 32.7 0.1 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFP05011.1 - 1.6e-12 46.2 0.4 0.0011 18.5 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP05011.1 - 1.4e-11 44.5 1.4 1.5e-07 31.6 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP05011.1 - 1.2e-10 41.0 0.1 0.002 18.6 0.0 4.3 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP05011.1 - 3.5e-10 39.6 1.9 2.2e-08 33.9 0.2 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP05011.1 - 5.2e-05 23.0 0.1 0.051 13.4 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 KFP05011.1 - 5.7e-05 22.7 0.9 0.29 10.6 0.0 3.2 2 2 1 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.1 KFP05011.1 - 0.00017 21.4 4.7 0.073 12.9 0.1 3.2 3 1 0 3 3 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KFP05011.1 - 0.0004 20.6 1.2 1.2 9.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 KFP05011.1 - 0.00065 20.0 1.3 0.12 12.6 0.2 2.8 2 1 0 2 2 2 1 Bacterial transcriptional activator domain NARP1 PF12569.3 KFP05011.1 - 0.001 17.9 0.1 1 8.0 0.0 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 Apc3 PF12895.2 KFP05011.1 - 0.0036 17.4 1.2 0.031 14.4 0.6 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFP05011.1 - 0.024 13.6 0.0 1.7 7.6 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP05011.1 - 0.039 13.8 0.3 12 5.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 KFP05011.1 - 0.078 12.8 1.3 11 5.8 0.9 3.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.7 KFP05011.1 - 0.084 12.4 2.7 2.3 7.8 0.1 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF627) Peptidase_M15_4 PF13539.1 KFP05011.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase MIT PF04212.13 KFP05011.1 - 0.27 11.1 6.1 7.8 6.4 0.1 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain XPC-binding PF09280.6 KFP05011.1 - 0.85 9.1 10.2 1.6 8.2 2.1 2.6 2 0 0 2 2 2 0 XPC-binding domain Peptidase_M3 PF01432.15 KFP05012.1 - 3.6e-165 550.4 0.0 4.6e-165 550.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF3740 PF12548.3 KFP05012.1 - 0.045 14.0 0.1 0.099 12.9 0.1 1.5 1 0 0 1 1 1 0 Sulfatase protein Peptidase_S8 PF00082.17 KFP05013.1 - 9.9e-44 149.5 1.4 1.6e-43 148.9 0.7 1.5 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFP05013.1 - 1.3e-29 101.7 0.1 2.3e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Imm18 PF15566.1 KFP05013.1 - 0.0011 18.2 0.5 0.74 9.1 0.0 2.5 2 0 0 2 2 2 2 Immunity protein 18 TB2_DP1_HVA22 PF03134.14 KFP05014.1 - 1.3e-25 88.9 1.8 1.5e-25 88.7 1.2 1.0 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ribosomal_S19 PF00203.16 KFP05015.1 - 1e-22 79.5 0.2 1.2e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 RRM_1 PF00076.17 KFP05016.1 - 5.2e-40 134.9 0.2 1.3e-19 69.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05016.1 - 7.6e-36 121.9 0.1 5.2e-17 61.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP05016.1 - 4.6e-18 64.8 0.2 9.4e-09 35.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFP05016.1 - 8e-05 22.3 0.3 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif NID PF07292.8 KFP05016.1 - 0.017 15.1 0.0 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) CSD PF00313.17 KFP05016.1 - 0.025 14.3 1.3 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DUF4651 PF15513.1 KFP05016.1 - 0.082 12.3 0.2 9.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Oxidored_q6 PF01058.17 KFP05018.1 - 6.5e-06 25.7 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 2 NADH ubiquinone oxidoreductase, 20 Kd subunit DIL PF01843.14 KFP05018.1 - 0.14 12.0 0.1 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 DIL domain Pkinase PF00069.20 KFP05019.1 - 3.9e-47 160.5 0.0 1.5e-30 106.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05019.1 - 3.8e-11 42.5 0.0 4.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Ephrin PF00812.12 KFP05020.1 - 5.4e-47 158.9 0.1 5.9e-47 158.8 0.1 1.0 1 0 0 1 1 1 1 Ephrin DUF1180 PF06679.7 KFP05021.1 - 1.2e-13 51.2 5.7 1.5e-12 47.6 4.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1180) RRM_1 PF00076.17 KFP05022.1 - 2.2e-26 91.2 0.1 3.6e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05022.1 - 6.8e-18 64.4 0.1 1.1e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP05022.1 - 2.2e-11 43.4 0.1 3.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP05022.1 - 0.063 13.1 0.2 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif DUF4140 PF13600.1 KFP05023.1 - 0.14 12.5 2.0 0.16 12.4 1.4 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ATP-synt_DE PF00401.15 KFP05023.1 - 0.56 10.1 11.7 2.7 7.9 7.8 2.0 1 1 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Spidroin_MaSp PF11260.3 KFP05023.1 - 0.75 9.9 3.4 0.83 9.7 2.4 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Pkinase PF00069.20 KFP05024.1 - 6e-57 192.7 0.0 7.3e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05024.1 - 2.5e-34 118.5 0.0 3.6e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP05024.1 - 2.4e-10 39.8 0.0 3.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP05024.1 - 0.048 13.3 0.1 1.1 8.9 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family RNA_pol_Rpb5_C PF01191.14 KFP05025.1 - 4.4e-35 119.1 1.1 7.2e-35 118.4 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KFP05025.1 - 2.6e-32 111.0 0.1 4.2e-32 110.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Calponin PF00402.13 KFP05026.1 - 5.6e-39 131.1 20.3 1.9e-14 52.6 0.8 3.8 3 0 0 3 3 3 3 Calponin family repeat CH PF00307.26 KFP05026.1 - 6.9e-18 64.6 0.1 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP05026.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 KFP05026.1 - 0.11 12.5 0.1 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin Membralin PF09746.4 KFP05027.1 - 9.3e-203 673.2 5.0 1.2e-202 672.9 3.5 1.1 1 0 0 1 1 1 1 Tumour-associated protein NVEALA PF14055.1 KFP05027.1 - 1.6 8.4 0.0 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 NVEALA protein ERGIC_N PF13850.1 KFP05027.1 - 3.6 7.6 5.5 2.2 8.3 0.4 2.8 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HR1 PF02185.11 KFP05028.1 - 0.016 14.9 0.2 0.023 14.4 0.2 1.3 1 0 0 1 1 1 0 Hr1 repeat WD40 PF00400.27 KFP05029.1 - 1.3e-25 88.3 5.3 9.9e-11 41.1 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_alt PF14077.1 KFP05029.1 - 2.6e-17 62.1 0.5 4.5e-17 61.4 0.4 1.4 1 0 0 1 1 1 1 Alternative WD40 repeat motif Nup160 PF11715.3 KFP05029.1 - 0.0059 14.8 0.5 0.095 10.8 0.1 2.0 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Med16 PF11635.3 KFP05030.1 - 4.4e-174 580.4 0.6 5.5e-174 580.1 0.4 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 WD40 PF00400.27 KFP05030.1 - 5.8e-08 32.3 2.9 2.7e-07 30.1 1.4 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFP05030.1 - 0.063 12.0 0.2 0.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like PAP2 PF01569.16 KFP05031.1 - 4.1e-12 45.8 4.1 6.4e-12 45.2 2.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF2085 PF09858.4 KFP05031.1 - 0.12 12.4 0.5 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) RRM_5 PF13893.1 KFP05032.1 - 1.6e-49 165.5 2.0 3.5e-13 49.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05032.1 - 1.4e-36 124.2 0.4 3.8e-10 39.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP05032.1 - 8.7e-35 118.1 0.1 1.9e-08 33.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nitroreductase PF00881.19 KFP05032.1 - 0.1 12.3 0.2 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 Nitroreductase family AKAP2_C PF15304.1 KFP05033.1 - 1.5e-51 176.0 47.2 4.9e-50 171.0 17.8 4.1 2 2 0 3 3 3 2 A-kinase anchor protein 2 C-terminus Trypsin PF00089.21 KFP05034.1 - 2.9e-51 174.1 0.0 3.7e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP05034.1 - 7.8e-05 22.0 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFP05034.1 - 0.00091 19.2 0.0 0.0085 16.0 0.0 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain zf-RING_2 PF13639.1 KFP05035.1 - 1e-15 57.2 7.0 1e-15 57.2 4.8 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFP05035.1 - 1.8e-08 34.3 3.6 4.4e-08 33.1 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFP05035.1 - 7.9e-08 32.2 6.3 7.9e-08 32.2 4.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP05035.1 - 8.9e-08 31.6 2.4 8.9e-08 31.6 1.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP05035.1 - 3e-07 30.0 5.1 3e-07 30.0 3.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFP05035.1 - 3.6e-07 29.7 5.6 3.6e-07 29.7 3.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFP05035.1 - 7.2e-05 22.5 3.5 0.0002 21.1 2.4 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 KFP05035.1 - 0.00076 19.4 6.5 0.0016 18.3 0.4 3.1 3 0 0 3 3 3 1 zinc-finger zf-RING_UBOX PF13445.1 KFP05035.1 - 0.0031 17.1 4.9 0.037 13.7 0.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 KFP05035.1 - 0.024 14.1 2.9 0.051 13.0 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF640 PF04852.7 KFP05035.1 - 0.029 14.5 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF640) Vps39_2 PF10367.4 KFP05035.1 - 0.041 14.0 0.8 8.5 6.5 0.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Opy2 PF09463.5 KFP05035.1 - 0.057 13.5 3.6 9.7 6.3 0.1 3.3 3 0 0 3 3 3 0 Opy2 protein Rad50_zn_hook PF04423.9 KFP05035.1 - 0.29 10.6 0.1 0.29 10.6 0.1 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 KFP05035.1 - 1.3 8.8 3.7 7.5 6.4 2.6 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFP05035.1 - 1.3 8.6 11.1 2.3 7.8 0.1 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KFP05035.1 - 2.1 8.4 5.0 4.2 7.4 3.5 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFP05035.1 - 3 7.8 7.9 54 3.8 5.5 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KFP05035.1 - 3.2 7.5 10.1 3.4 7.4 3.9 2.4 2 0 0 2 2 2 0 PHD-finger FGF PF00167.13 KFP05036.1 - 1.6e-31 108.5 0.0 1.8e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor Mem_trans PF03547.13 KFP05037.1 - 0.14 10.4 0.3 0.14 10.4 0.2 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF4652 PF15525.1 KFP05037.1 - 0.16 11.3 1.5 0.17 11.3 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) RNA_pol PF00940.14 KFP05038.1 - 2.6e-148 493.8 0.0 3.4e-148 493.4 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KFP05038.1 - 1.6e-44 152.4 0.0 2.9e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal cNMP_binding PF00027.24 KFP05039.1 - 5.7e-21 74.1 0.0 1e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 KFP05039.1 - 5.5e-19 68.2 10.8 1.3e-18 67.0 7.5 1.6 1 0 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.5 KFP05039.1 - 1.8e-13 49.5 0.4 1.8e-13 49.5 0.3 2.4 2 0 0 2 2 2 1 Ion transport protein N-terminal Ion_trans_2 PF07885.11 KFP05039.1 - 0.00077 19.1 0.2 0.003 17.2 0.1 2.0 2 0 0 2 2 2 1 Ion channel Ig_2 PF13895.1 KFP05040.1 - 5.6e-13 48.8 3.8 3.8e-08 33.3 0.2 3.3 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.11 KFP05040.1 - 1.6e-12 47.1 0.9 8e-09 35.2 0.0 3.4 3 1 1 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.12 KFP05040.1 - 2.6e-08 33.7 3.5 0.00034 20.4 0.1 3.6 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP05040.1 - 9.9e-07 29.1 13.4 0.006 17.0 1.8 4.2 4 1 0 4 4 4 2 Immunoglobulin domain Orthoreo_P10 PF07204.6 KFP05040.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 ig PF00047.20 KFP05040.1 - 0.027 14.5 10.0 1.7 8.8 0.3 4.2 4 1 0 4 4 4 0 Immunoglobulin domain C2-set PF05790.10 KFP05040.1 - 0.13 12.2 0.0 2.2 8.3 0.0 3.0 4 0 0 4 4 4 0 Immunoglobulin C2-set domain UQ_con PF00179.21 KFP05041.1 - 5e-46 155.6 0.0 6.5e-46 155.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP05041.1 - 0.0044 16.7 0.0 0.015 15.0 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B MFS_1 PF07690.11 KFP05042.1 - 8.1e-34 116.8 38.0 2.5e-33 115.2 26.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily PID PF00640.18 KFP05043.1 - 8.5e-30 103.5 0.0 1.2e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) C2 PF00168.25 KFP05044.1 - 3e-10 39.7 0.0 5.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Herpes_LP PF03363.8 KFP05044.1 - 1.5 8.3 13.8 0.24 10.9 2.4 2.7 2 1 0 2 2 2 0 Herpesvirus leader protein ELM2 PF01448.19 KFP05045.1 - 5e-14 52.6 0.1 1.8e-13 50.8 0.0 2.1 1 0 0 1 1 1 1 ELM2 domain Myb_DNA-binding PF00249.26 KFP05045.1 - 2.9e-05 24.0 0.3 6.3e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2002 PF09400.5 KFP05045.1 - 0.085 12.5 0.2 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) PAP2 PF01569.16 KFP05046.1 - 3.1e-23 81.8 1.4 3.1e-23 81.8 1.0 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KFP05046.1 - 0.0079 16.4 2.3 0.0079 16.4 1.6 2.2 2 1 0 2 2 2 1 PAP2 superfamily C-terminal DUF389 PF04087.9 KFP05046.1 - 0.048 13.6 0.3 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF389) DUF2976 PF11190.3 KFP05046.1 - 0.22 11.0 3.9 0.17 11.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) TLE_N PF03920.10 KFP05047.1 - 5.2e-66 220.5 10.6 7e-66 220.1 7.4 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HALZ PF02183.13 KFP05047.1 - 0.031 13.9 0.7 0.069 12.8 0.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper TLE_N PF03920.10 KFP05048.1 - 2.2e-68 228.2 7.8 2.8e-68 227.8 5.4 1.1 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain HALZ PF02183.13 KFP05048.1 - 0.00083 19.0 1.3 0.0024 17.5 0.9 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper FliG_N PF14842.1 KFP05048.1 - 0.022 14.8 0.5 0.051 13.6 0.1 1.8 2 0 0 2 2 2 0 FliG N-terminal domain FliG_M PF14841.1 KFP05048.1 - 0.078 12.9 0.7 0.21 11.6 0.2 1.8 1 1 1 2 2 2 0 FliG middle domain DUF2828 PF11443.3 KFP05048.1 - 0.082 11.0 0.1 0.098 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Orthopox_A5L PF06193.6 KFP05048.1 - 0.1 12.5 0.5 3.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like G-alpha PF00503.15 KFP05049.1 - 1.4e-117 392.7 2.0 1.5e-117 392.5 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP05049.1 - 3.5e-12 45.9 0.2 2.2e-11 43.3 0.2 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP05049.1 - 0.0062 16.4 0.1 0.48 10.4 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFP05049.1 - 0.035 14.6 0.1 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Trypsin PF00089.21 KFP05050.1 - 1.9e-24 86.4 0.0 5.3e-17 62.1 0.0 2.0 1 1 1 2 2 2 2 Trypsin DUF1986 PF09342.6 KFP05050.1 - 0.057 12.6 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Trypsin PF00089.21 KFP05051.1 - 7.3e-60 202.2 0.0 8.2e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFP05051.1 - 0.11 12.4 0.2 0.91 9.5 0.2 2.3 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_M28 PF04389.12 KFP05052.1 - 1.9e-11 44.0 0.0 3.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 KFP05052.1 - 7.4e-07 28.6 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Nicastrin RRM_1 PF00076.17 KFP05053.1 - 1.7e-37 126.9 0.0 5.5e-17 61.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05053.1 - 8.9e-26 89.6 0.2 1.8e-11 43.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP05053.1 - 2.1e-24 85.0 0.1 4.1e-10 39.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KFP05053.1 - 0.0091 15.9 0.0 0.62 10.0 0.0 2.5 2 0 0 2 2 2 1 RNA binding domain Peripla_BP_4 PF13407.1 KFP05053.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Nup35_RRM_2 PF14605.1 KFP05053.1 - 0.11 12.2 0.0 1.4 8.7 0.0 2.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif CAF1-p150_C2 PF15539.1 KFP05055.1 - 8.9e-113 376.2 1.3 8.9e-113 376.2 0.9 1.9 2 0 0 2 2 2 1 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF-1_p150 PF11600.3 KFP05055.1 - 5.5e-71 238.3 64.0 5.5e-71 238.3 44.4 3.0 5 0 0 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CAF1-p150_N PF15557.1 KFP05055.1 - 3.4e-36 124.7 6.2 9.1e-36 123.3 4.3 1.8 1 0 0 1 1 1 1 CAF1 complex subunit p150, region binding to PCNA CAF1A PF12253.3 KFP05055.1 - 2.1e-27 95.0 9.7 2.1e-27 95.0 6.7 4.5 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A PUB PF09409.5 KFP05056.1 - 3.3e-22 78.0 0.1 6.3e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 PUB domain UBX PF00789.15 KFP05056.1 - 1.5e-09 37.7 0.0 3.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 UBX domain LEDGF PF11467.3 KFP05057.1 - 3.3e-39 132.8 2.2 7.9e-39 131.6 1.5 1.6 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) PWWP PF00855.12 KFP05057.1 - 6.3e-07 29.5 3.4 1.6e-06 28.1 0.0 2.7 2 0 0 2 2 2 1 PWWP domain Perilipin PF03036.11 KFP05058.1 - 4.1e-141 470.3 20.8 2.3e-140 467.8 14.4 1.8 1 1 0 1 1 1 1 Perilipin family Prefoldin_3 PF13758.1 KFP05058.1 - 0.0034 17.1 0.3 0.01 15.5 0.2 1.9 2 0 0 2 2 2 1 Prefoldin subunit YbjQ_1 PF01906.12 KFP05058.1 - 0.0079 16.6 2.4 0.072 13.5 0.3 2.5 2 0 0 2 2 2 1 Putative heavy-metal-binding DUF1662 PF07878.6 KFP05058.1 - 0.043 13.5 0.7 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) DUF445 PF04286.7 KFP05058.1 - 0.072 12.5 1.2 0.18 11.2 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF445) PilJ PF13675.1 KFP05058.1 - 0.26 11.6 10.2 1.9 8.8 0.1 3.0 2 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Phage_GPO PF05929.6 KFP05058.1 - 1.2 8.3 6.5 0.32 10.2 1.7 1.8 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Carbpep_Y_N PF05388.6 KFP05058.1 - 1.2 9.3 5.5 4.3 7.5 1.6 3.2 3 1 0 3 3 3 0 Carboxypeptidase Y pro-peptide DUF4404 PF14357.1 KFP05058.1 - 1.4 9.4 7.6 8.6 6.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) YlbD_coat PF14071.1 KFP05058.1 - 4 7.5 6.7 0.38 10.8 0.7 2.3 2 1 0 2 2 2 0 Putative coat protein Hpt PF01627.18 KFP05058.1 - 6.9 6.7 10.1 2.5 8.1 3.4 2.8 2 0 0 2 2 2 0 Hpt domain Glypican PF01153.14 KFP05059.1 - 6.5e-116 388.1 1.7 7.3e-116 388.0 1.2 1.0 1 0 0 1 1 1 1 Glypican DUF713 PF05218.9 KFP05059.1 - 0.013 15.1 0.2 0.053 13.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF713) fn3 PF00041.16 KFP05061.1 - 2.1e-134 438.0 24.6 2.5e-16 59.5 0.0 9.3 9 0 0 9 9 9 9 Fibronectin type III domain Fibrinogen_C PF00147.13 KFP05061.1 - 3.5e-67 226.4 10.7 1.4e-66 224.4 7.4 1.9 1 1 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EGF_2 PF07974.8 KFP05061.1 - 1.7e-12 47.2 99.5 0.00029 20.9 9.3 6.0 6 0 0 6 6 6 4 EGF-like domain hEGF PF12661.2 KFP05061.1 - 3.4e-12 45.6 42.6 0.0037 17.2 0.8 5.9 5 0 0 5 5 5 5 Human growth factor-like EGF Interfer-bind PF09294.5 KFP05061.1 - 7.2e-12 45.2 0.0 0.76 9.8 0.0 7.9 8 1 1 9 9 9 3 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.4 KFP05061.1 - 0.015 14.4 0.3 13 4.8 0.0 4.0 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) EGF PF00008.22 KFP05061.1 - 0.42 10.6 84.7 0.017 15.0 8.0 6.3 6 0 0 6 6 6 0 EGF-like domain SusE PF14292.1 KFP05061.1 - 8 6.3 13.0 35 4.2 0.0 6.2 7 0 0 7 7 7 0 SusE outer membrane protein TNF PF00229.13 KFP05062.1 - 2.7e-19 68.9 0.1 4.5e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family TNF PF00229.13 KFP05063.1 - 1.4e-34 118.4 0.1 1.8e-34 118.0 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family C1q PF00386.16 KFP05063.1 - 0.17 11.9 0.3 0.38 10.7 0.2 1.7 1 1 0 1 1 1 0 C1q domain DUF4481 PF14800.1 KFP05064.1 - 1.8e-47 161.8 4.6 1.9e-47 161.6 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) COQ7 PF03232.8 KFP05064.1 - 0.04 13.3 0.1 0.063 12.7 0.1 1.3 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 V-ATPase_G PF03179.10 KFP05065.1 - 7.7e-24 84.0 6.6 8.6e-24 83.8 4.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_F6 PF05511.6 KFP05065.1 - 0.036 13.9 0.3 0.046 13.6 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 GA PF01468.12 KFP05065.1 - 0.12 12.5 1.9 0.14 12.3 0.9 1.4 1 1 0 1 1 1 0 GA module Frigida PF07899.6 KFP05065.1 - 0.2 10.4 2.4 0.22 10.2 1.7 1.2 1 0 0 1 1 1 0 Frigida-like protein DUF2315 PF10231.4 KFP05065.1 - 0.32 10.8 1.6 0.38 10.6 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Sds3 PF08598.6 KFP05065.1 - 1.7 8.0 8.3 1.4e+02 1.9 5.7 2.0 1 1 0 1 1 1 0 Sds3-like PDZ PF00595.19 KFP05066.1 - 1.4e-25 89.2 0.7 2.7e-15 56.2 0.1 2.7 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP05066.1 - 2.3e-08 33.8 0.0 0.00013 21.8 0.0 3.2 2 1 1 3 3 3 2 PDZ domain Sec1 PF00995.18 KFP05067.1 - 4e-18 65.3 0.0 4.4e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 KFP05068.1 - 1.2e-124 417.0 4.3 1.4e-124 416.8 2.9 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.1 KFP05068.1 - 0.0076 16.3 0.7 0.019 14.9 0.5 1.6 1 0 0 1 1 1 1 Putative coat protein Rapamycin_bind PF08771.6 KFP05068.1 - 0.017 15.2 0.5 0.99 9.5 0.2 2.5 2 0 0 2 2 2 0 Rapamycin binding domain Ctr PF04145.10 KFP05069.1 - 1.4e-20 73.7 0.7 2e-20 73.2 0.5 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Ion_trans PF00520.26 KFP05070.1 - 2.8e-213 702.4 80.4 4.9e-58 195.6 16.1 4.4 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.6 KFP05070.1 - 9.2e-14 50.3 0.0 3.7e-13 48.4 0.0 2.1 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.7 KFP05070.1 - 2.8e-07 29.3 82.1 5.7e-06 25.0 6.9 9.2 7 3 2 9 9 9 5 Polycystin cation channel Tmemb_9 PF05434.6 KFP05070.1 - 0.04 13.6 1.3 12 5.6 0.0 3.2 3 0 0 3 3 3 0 TMEM9 Ank_2 PF12796.2 KFP05071.1 - 1.2e-57 192.2 6.3 1.4e-26 92.6 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP05071.1 - 2.8e-52 172.0 4.5 7e-08 31.9 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFP05071.1 - 5e-44 147.9 8.0 6.4e-14 52.0 0.0 5.5 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP05071.1 - 2.6e-41 138.7 12.5 5.1e-09 36.0 0.1 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP05071.1 - 5.7e-40 131.3 4.9 1.6e-06 27.7 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat SET PF00856.23 KFP05071.1 - 1.9e-27 96.5 0.1 1.9e-27 96.5 0.1 3.4 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.11 KFP05071.1 - 8.7e-19 67.7 13.5 8.7e-19 67.7 9.3 3.8 3 1 0 3 3 3 1 Pre-SET motif Arrestin_C PF02752.17 KFP05072.1 - 1.5e-20 73.7 0.1 3.2e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KFP05072.1 - 1.2e-19 70.5 0.1 9.6e-18 64.4 0.0 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KFP05072.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Arrestin_N terminal like Gln-synt_C PF00120.19 KFP05073.1 - 3.8e-63 213.0 0.0 4.6e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KFP05073.1 - 1.2e-18 66.4 0.0 1.9e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain COBRA1 PF06209.8 KFP05074.1 - 5e-266 882.7 3.0 5.9e-266 882.4 2.1 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) TFCD_C PF12612.3 KFP05074.1 - 0.054 12.9 0.1 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal GDA1_CD39 PF01150.12 KFP05075.1 - 7.1e-33 113.7 0.0 8.2e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Tubulin_C PF03953.12 KFP05076.1 - 1.4e-50 170.5 0.1 2.4e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KFP05076.1 - 6.1e-44 150.4 0.0 1e-43 149.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 KFP05076.1 - 0.0058 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF2475 PF10629.4 KFP05078.1 - 1.2e-07 31.8 0.1 7.7e-05 22.8 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2475) DUF2475 PF10629.4 KFP05079.1 - 3.1e-13 49.7 0.1 3.1e-13 49.7 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2475) Pkinase_Tyr PF07714.12 KFP05080.1 - 2.4e-84 282.4 0.0 3.3e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP05080.1 - 2e-44 151.6 0.0 3.4e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.1 KFP05080.1 - 0.00061 19.5 0.5 0.0011 18.7 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family F5_F8_type_C PF00754.20 KFP05080.1 - 0.003 17.3 0.8 0.011 15.5 0.0 2.3 3 0 0 3 3 3 1 F5/8 type C domain Mid2 PF04478.7 KFP05080.1 - 0.0079 15.6 0.5 0.015 14.7 0.3 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rifin_STEVOR PF02009.11 KFP05080.1 - 0.014 15.0 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Rifin/stevor family Kinase-like PF14531.1 KFP05080.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like F5_F8_type_C PF00754.20 KFP05081.1 - 1.9e-13 50.3 0.0 2.2e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Phe_ZIP PF08916.6 KFP05081.1 - 0.13 12.5 0.2 0.4 11.0 0.1 1.7 2 0 0 2 2 2 0 Phenylalanine zipper Torsin PF06309.6 KFP05082.1 - 2.3e-14 53.3 0.0 6.4e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 Torsin AAA_22 PF13401.1 KFP05082.1 - 0.0058 16.7 0.2 0.29 11.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFP05082.1 - 0.013 15.7 0.1 0.088 13.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KFP05082.1 - 0.022 14.9 0.0 0.064 13.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFP05082.1 - 0.034 14.1 0.0 0.2 11.6 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 KFP05082.1 - 0.087 11.7 0.0 0.28 10.1 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Cullin PF00888.17 KFP05083.1 - 7.6e-73 245.9 9.2 3.6e-71 240.4 1.5 3.3 2 1 1 3 3 3 2 Cullin family APC2 PF08672.6 KFP05083.1 - 1e-23 83.3 0.6 3.1e-23 81.7 0.4 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Ribosomal_S2 PF00318.15 KFP05083.1 - 0.038 13.1 0.1 0.32 10.2 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S2 Phostensin PF13914.1 KFP05084.1 - 2.4e-40 137.7 6.3 1.2e-39 135.4 0.6 2.4 2 0 0 2 2 2 2 Phostensin PP1-binding and SH3-binding region IQ PF00612.22 KFP05085.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.7 4 0 0 4 4 4 0 IQ calmodulin-binding motif MRP-L27 PF09809.4 KFP05086.1 - 2.5e-45 152.7 0.0 2.9e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 WD40 PF00400.27 KFP05087.1 - 2e-10 40.1 5.5 2.9e-05 23.7 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat zf-MYND PF01753.13 KFP05088.1 - 4e-08 33.0 15.5 6.3e-08 32.3 10.7 1.4 1 0 0 1 1 1 1 MYND finger HNH_3 PF13392.1 KFP05088.1 - 5.6e-05 22.4 0.1 0.00012 21.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease zf-TAZ PF02135.11 KFP05088.1 - 2.7 8.0 11.1 4.3 7.4 7.7 1.2 1 0 0 1 1 1 0 TAZ zinc finger DUF2665 PF11654.3 KFP05089.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) SHIPPO-rpt PF07004.7 KFP05090.1 - 0.029 15.2 0.1 0.067 14.1 0.1 1.7 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat TP1 PF02079.11 KFP05090.1 - 0.13 12.0 0.1 15 5.4 0.0 2.1 2 0 0 2 2 2 0 Nuclear transition protein 1 Ribosomal_L11 PF00298.14 KFP05091.1 - 5.3e-12 45.7 0.1 7.3e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 KFP05091.1 - 7.9e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain LRR_8 PF13855.1 KFP05092.1 - 1.5e-21 75.8 16.5 1.2e-09 37.8 2.7 4.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 KFP05092.1 - 2.3e-17 62.2 18.3 8.6e-10 38.0 2.6 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP05092.1 - 1.8e-12 45.4 10.2 0.066 13.2 0.0 6.8 6 0 0 6 6 6 4 Leucine Rich Repeat zf-C3HC4_3 PF13920.1 KFP05092.1 - 2.1e-12 46.4 20.1 2.1e-12 46.4 13.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LRR_7 PF13504.1 KFP05092.1 - 2.5e-06 26.7 18.7 0.22 11.8 0.1 7.1 7 0 0 7 7 6 3 Leucine rich repeat SAM_1 PF00536.25 KFP05092.1 - 9.9e-06 25.6 0.8 0.00022 21.3 0.0 3.1 3 0 0 3 3 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP05092.1 - 0.00085 19.1 0.3 0.0055 16.5 0.0 2.7 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_2 PF13923.1 KFP05092.1 - 0.0043 17.0 23.1 0.0043 17.0 16.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KFP05092.1 - 0.0086 15.5 10.5 0.018 14.5 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 LRR_6 PF13516.1 KFP05092.1 - 0.041 13.9 7.4 18 5.8 0.2 5.0 4 0 0 4 4 4 0 Leucine Rich repeat zf-RING_2 PF13639.1 KFP05092.1 - 0.088 12.6 21.8 0.21 11.4 15.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 KFP05092.1 - 7 6.4 26.3 0.47 10.2 14.7 1.7 2 0 0 2 2 1 0 zinc-RING finger domain Ctr PF04145.10 KFP05093.1 - 3.7e-48 163.2 5.2 4.7e-48 162.9 3.6 1.1 1 0 0 1 1 1 1 Ctr copper transporter family HAD_2 PF13419.1 KFP05094.1 - 7e-24 84.9 0.0 8.3e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFP05094.1 - 2.2e-10 40.1 0.0 3.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFP05094.1 - 1.9e-07 31.7 0.0 2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ALAD PF00490.16 KFP05095.1 - 1.2e-113 379.2 0.0 1.5e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CBFD_NFYB_HMF PF00808.18 KFP05096.1 - 1.6e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SpoU_methylase PF00588.14 KFP05096.1 - 0.0055 16.5 0.0 0.0068 16.2 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Histone PF00125.19 KFP05096.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1510 PF07423.6 KFP05096.1 - 0.011 15.1 10.1 0.0099 15.2 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 KFP05096.1 - 0.057 11.9 12.8 0.052 12.0 8.9 1.1 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 KFP05096.1 - 0.059 12.8 11.0 0.066 12.7 7.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 KFP05096.1 - 0.15 10.0 11.1 0.15 10.0 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 KFP05096.1 - 0.35 10.3 11.9 0.39 10.2 8.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2956 PF11169.3 KFP05096.1 - 0.39 10.6 8.6 0.59 10.1 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) FLO_LFY PF01698.11 KFP05096.1 - 0.42 9.3 7.0 0.45 9.3 4.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Vfa1 PF08432.5 KFP05096.1 - 0.53 10.2 15.0 0.63 10.0 10.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TraH_2 PF06871.6 KFP05096.1 - 0.54 9.6 4.9 0.65 9.4 3.4 1.1 1 0 0 1 1 1 0 TraH_2 Peptidase_S49_N PF08496.5 KFP05096.1 - 0.75 9.5 4.0 0.91 9.2 2.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GAGA_bind PF06217.7 KFP05096.1 - 1 9.2 5.7 1.1 9.1 4.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CobT PF06213.7 KFP05096.1 - 1.1 8.3 15.8 1.1 8.2 11.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.12 KFP05096.1 - 1.4 8.7 5.6 1.3 8.7 3.9 1.1 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 KFP05096.1 - 2.7 5.5 6.9 2.6 5.6 4.8 1.0 1 0 0 1 1 1 0 Ycf1 PBP_sp32 PF07222.7 KFP05096.1 - 4.2 6.4 10.6 4.8 6.2 7.3 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nucleoplasmin PF03066.10 KFP05096.1 - 4.5 6.7 14.3 5.9 6.3 9.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 KFP05096.1 - 6.3 5.8 11.4 8.2 5.4 7.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4337 PF14235.1 KFP05096.1 - 7.1 6.4 5.9 8.9 6.1 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3987 PF13148.1 KFP05096.1 - 8.4 4.8 9.7 10 4.5 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NPR3 PF03666.8 KFP05096.1 - 8.9 4.7 8.1 10 4.5 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 C2 PF00168.25 KFP05097.1 - 5.6e-17 61.3 0.1 7.7e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 KFP05097.1 - 0.00082 18.9 0.0 0.00099 18.6 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain Pep_M12B_propep PF01562.14 KFP05097.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide RGS PF00615.14 KFP05098.1 - 1.2e-38 131.8 4.3 1.3e-38 131.6 3.0 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain RloB PF13707.1 KFP05098.1 - 0.059 13.0 1.4 0.066 12.8 1.0 1.1 1 0 0 1 1 1 0 RloB-like protein zf-C2H2_6 PF13912.1 KFP05099.1 - 3e-10 39.6 27.9 2.8e-07 30.2 0.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFP05099.1 - 2.7e-07 30.4 24.1 0.0046 17.1 1.7 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP05099.1 - 1.3e-06 28.3 28.6 0.24 11.8 2.0 5.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type Dimer_Tnp_hAT PF05699.9 KFP05099.1 - 2.1e-05 24.0 0.1 5.7e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KFP05099.1 - 0.00062 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-met PF12874.2 KFP05099.1 - 0.067 13.4 0.5 0.067 13.4 0.3 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DBD_Tnp_Hermes PF10683.4 KFP05099.1 - 0.071 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain zf-H2C2_2 PF13465.1 KFP05099.1 - 0.073 13.3 23.3 1.6 9.1 0.9 5.6 5 0 0 5 5 5 0 Zinc-finger double domain zf-BED PF02892.10 KFP05099.1 - 0.13 12.0 23.2 1.2 9.0 2.2 4.8 5 0 0 5 5 5 0 BED zinc finger Lig_chan PF00060.21 KFP05100.1 - 2.3e-32 111.7 0.1 3.9e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel ANF_receptor PF01094.23 KFP05100.1 - 2.6e-30 105.4 0.0 2.9e-29 101.9 0.0 2.6 1 1 0 1 1 1 1 Receptor family ligand binding region SBP_bac_3 PF00497.15 KFP05100.1 - 2.4e-21 76.0 0.0 6e-21 74.7 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFP05100.1 - 1.4e-19 69.8 0.0 3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site CaM_bdg_C0 PF10562.4 KFP05100.1 - 4e-16 58.5 3.6 7.6e-16 57.6 2.5 1.5 1 0 0 1 1 1 1 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peripla_BP_6 PF13458.1 KFP05100.1 - 4.4e-05 23.0 0.0 0.0001 21.7 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein zf-RING_2 PF13639.1 KFP05101.1 - 7.3e-08 32.1 6.3 7.3e-08 32.1 4.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFP05101.1 - 8.7e-06 25.3 4.8 8.7e-06 25.3 3.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP05101.1 - 0.00026 20.8 0.3 0.00026 20.8 0.2 2.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFP05101.1 - 0.00036 20.1 0.3 0.00036 20.1 0.2 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFP05101.1 - 0.0016 18.0 4.5 0.0016 18.0 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP05102.1 - 0.00065 19.4 12.5 0.00065 19.4 8.7 2.4 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFP05102.1 - 0.0031 17.2 14.3 0.0031 17.2 9.9 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFP05102.1 - 0.015 14.9 14.1 0.015 14.9 9.8 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP05102.1 - 0.015 15.3 14.6 0.015 15.3 10.1 3.1 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFP05102.1 - 0.071 12.8 10.4 0.12 12.1 6.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger PhnA_Zn_Ribbon PF08274.7 KFP05102.1 - 0.44 10.3 7.9 17 5.3 0.0 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon ADK_lid PF05191.9 KFP05102.1 - 0.45 10.2 9.7 0.22 11.2 2.6 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid GcpE PF04551.9 KFP05102.1 - 0.74 8.5 4.7 0.19 10.5 0.5 1.7 1 1 0 2 2 2 0 GcpE protein FYVE PF01363.16 KFP05102.1 - 6.7 6.6 15.5 27 4.7 10.8 2.2 1 1 0 1 1 1 0 FYVE zinc finger DUF329 PF03884.9 KFP05102.1 - 8.8 5.9 10.2 6.1 6.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF329) zf-RING_2 PF13639.1 KFP05103.1 - 7.4e-10 38.4 6.6 1.1e-09 38.0 4.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFP05103.1 - 1.3e-09 37.6 5.0 1.9e-09 37.0 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFP05103.1 - 1.5e-08 34.1 5.3 2.7e-08 33.3 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP05103.1 - 6.1e-08 32.2 6.8 1.8e-07 30.7 4.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP05103.1 - 3.6e-07 29.9 3.3 8.3e-07 28.7 2.3 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFP05103.1 - 5.1e-07 29.3 1.0 5.1e-07 29.3 0.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFP05103.1 - 1.3e-06 28.2 6.4 2.2e-06 27.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFP05103.1 - 2.4e-05 23.8 6.0 7.6e-05 22.2 4.2 1.8 1 1 1 2 2 2 2 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KFP05103.1 - 0.0042 16.8 3.0 0.0066 16.2 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFP05103.1 - 0.01 15.9 5.5 0.012 15.7 3.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DUF4428 PF14471.1 KFP05103.1 - 0.044 13.5 3.6 0.55 10.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-P11 PF03854.9 KFP05103.1 - 0.08 12.4 10.6 0.18 11.3 2.8 2.7 1 1 1 2 2 2 0 P-11 zinc finger NMD3 PF04981.8 KFP05103.1 - 0.18 10.9 3.4 0.2 10.7 2.4 1.1 1 0 0 1 1 1 0 NMD3 family DUF329 PF03884.9 KFP05103.1 - 0.24 10.9 6.0 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF329) FYVE PF01363.16 KFP05103.1 - 0.4 10.5 4.2 0.91 9.4 3.0 1.6 1 1 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.1 KFP05103.1 - 0.76 9.3 11.0 7.8 6.1 0.2 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 KFP05103.1 - 1.5 8.5 3.7 2 8.1 2.6 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DZR PF12773.2 KFP05103.1 - 4 7.3 7.5 51 3.8 5.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.15 KFP05103.1 - 4.2 6.9 9.2 89 2.7 6.4 2.4 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.10 KFP05103.1 - 4.7 6.8 8.0 6.1 6.4 2.8 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger DUF1644 PF07800.7 KFP05103.1 - 8.2 6.2 7.0 9.2 6.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-met2 PF12907.2 KFP05103.1 - 9.1 6.3 6.9 96 3.0 1.9 3.4 3 1 0 3 3 3 0 Zinc-binding FAD_binding_1 PF00667.15 KFP05104.1 - 2.5e-48 164.3 0.0 3.9e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFP05104.1 - 1.7e-33 115.6 0.0 2.6e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFP05104.1 - 3.1e-17 63.1 0.0 5.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HTH_20 PF12840.2 KFP05104.1 - 0.09 12.6 0.6 7 6.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Tmemb_185A PF10269.4 KFP05105.1 - 5.3e-07 29.4 16.0 1.7e-05 24.5 2.8 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein GDA1_CD39 PF01150.12 KFP05106.1 - 1e-99 334.0 0.0 1.4e-99 333.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SH3_1 PF00018.23 KFP05107.1 - 1.3e-16 59.7 0.0 6e-13 47.9 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFP05107.1 - 1.3e-10 40.7 0.0 1.3e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KFP05107.1 - 5.2e-07 29.0 0.0 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 KFP05107.1 - 0.00014 21.4 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.12 KFP05108.1 - 1.2e-08 34.2 1.8 0.0034 17.1 0.0 3.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFP05108.1 - 7.4e-08 31.9 0.2 0.00077 19.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFP05108.1 - 2.8e-07 29.8 0.0 0.0014 18.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP05108.1 - 1.9e-06 27.7 1.8 1.7e-05 24.6 1.3 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP05108.1 - 0.00028 20.4 0.1 0.022 14.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP05108.1 - 0.0004 20.1 0.2 0.56 10.0 0.0 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP05108.1 - 0.00076 19.9 0.6 0.026 15.1 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP05108.1 - 0.0022 18.1 1.0 0.0092 16.1 0.3 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFP05108.1 - 0.011 16.1 0.3 0.14 12.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFP05108.1 - 0.041 14.2 0.6 0.12 12.6 0.4 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Apc5 PF12862.2 KFP05108.1 - 0.14 12.0 0.6 0.35 10.7 0.4 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DNA_pol_A_exo1 PF01612.15 KFP05109.1 - 7.8e-21 74.3 0.1 1.9e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Mut7-C PF01927.11 KFP05109.1 - 2.3e-14 53.6 0.7 5.2e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 Mut7-C RNAse domain Fels1 PF05666.6 KFP05109.1 - 0.056 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like Kunitz_BPTI PF00014.18 KFP05110.1 - 1.2e-35 121.4 21.9 5.8e-18 64.8 5.0 2.6 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Lipocalin PF00061.18 KFP05110.1 - 2e-27 95.9 0.0 2.7e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Ras PF00071.17 KFP05111.1 - 8.1e-12 44.8 0.1 1e-05 24.9 0.2 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFP05111.1 - 3.7e-08 33.8 0.0 3.7e-08 33.8 0.0 3.4 3 1 0 3 3 3 1 Miro-like protein Arf PF00025.16 KFP05111.1 - 5.5e-06 25.7 0.1 1.8e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP05111.1 - 0.0016 18.3 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KFP05111.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-MYND PF01753.13 KFP05112.1 - 0.00028 20.7 15.9 0.00052 19.8 11.0 1.5 1 0 0 1 1 1 1 MYND finger Ocnus PF05005.10 KFP05113.1 - 4.1e-23 81.3 0.0 4.5e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) fn1 PF00039.13 KFP05113.1 - 0.033 14.0 0.1 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type I domain PPO1_DWL PF12142.3 KFP05113.1 - 0.042 13.3 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Polyphenol oxidase middle domain MBF1 PF08523.5 KFP05114.1 - 6.9e-29 99.6 4.5 6.9e-29 99.6 3.1 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KFP05114.1 - 1.4e-12 47.2 0.2 2.2e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KFP05114.1 - 2.1e-05 24.4 0.1 3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KFP05114.1 - 0.0004 20.5 0.0 0.00069 19.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain BTB PF00651.26 KFP05115.1 - 3.6e-26 91.3 0.0 6.3e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP05115.1 - 3.5e-10 39.6 17.1 1.7e-06 28.0 0.4 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP05115.1 - 2.7e-08 33.6 24.2 0.00029 20.9 1.5 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP05115.1 - 1.4e-06 28.1 16.8 0.034 14.4 0.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger DUF968 PF06147.6 KFP05115.1 - 0.25 11.2 8.0 0.44 10.4 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) zf-C2H2_jaz PF12171.3 KFP05115.1 - 0.33 11.1 15.1 5 7.3 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP05115.1 - 1.5 9.1 13.7 2.1 8.7 0.5 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP05115.1 - 5.4 7.0 11.8 5 7.1 0.3 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger BTB PF00651.26 KFP05116.1 - 2.4e-26 91.9 0.2 3.9e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFP05116.1 - 5.7e-17 60.9 17.0 2.9e-05 24.1 1.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP05116.1 - 2e-13 49.8 16.2 5.1e-07 29.6 0.4 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP05116.1 - 1.2e-12 47.2 12.7 0.00032 20.8 0.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFP05116.1 - 3.2e-08 33.5 8.3 0.0047 17.0 0.1 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP05116.1 - 5.5e-07 29.5 7.0 0.025 14.7 0.3 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF3342 PF11822.3 KFP05116.1 - 1.4e-05 24.4 0.1 1.4e-05 24.4 0.1 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3342) zf-BED PF02892.10 KFP05116.1 - 2.4e-05 23.9 15.3 0.069 12.9 0.4 3.5 2 1 1 3 3 3 3 BED zinc finger zf-C2H2_2 PF12756.2 KFP05116.1 - 0.022 14.8 10.9 0.11 12.6 0.0 3.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF4187 PF13821.1 KFP05116.1 - 0.36 10.4 2.8 6.3 6.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) zf-Di19 PF05605.7 KFP05116.1 - 0.64 10.1 8.9 1.8 8.7 2.7 3.2 3 1 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFP05116.1 - 0.83 9.3 11.3 4.2 7.1 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_1 PF00130.17 KFP05116.1 - 3.3 7.5 7.2 5.4 6.8 0.6 2.8 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PyrI_C PF02748.10 KFP05116.1 - 3.7 7.0 8.4 7.6 6.0 0.1 3.5 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-trcl PF13451.1 KFP05116.1 - 4 7.1 7.7 3.6 7.2 3.0 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain RasGEF PF00617.14 KFP05117.1 - 1.6e-54 184.5 1.2 2.7e-54 183.7 0.8 1.4 1 1 0 1 1 1 1 RasGEF domain PH PF00169.24 KFP05117.1 - 8.8e-07 29.0 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Fibrinogen_C PF00147.13 KFP05118.1 - 5.6e-77 258.4 12.3 8e-77 257.9 8.5 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Fer4_NifH PF00142.13 KFP05118.1 - 0.01 15.0 2.1 0.02 14.0 1.4 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF2115 PF09888.4 KFP05118.1 - 0.01 15.9 4.8 0.02 14.9 3.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) WD40 PF00400.27 KFP05119.1 - 5.2e-20 70.5 14.8 3.5e-08 33.0 0.0 6.9 7 2 0 7 7 7 4 WD domain, G-beta repeat F-box-like PF12937.2 KFP05119.1 - 3e-08 33.2 5.2 7.5e-08 31.9 2.3 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFP05119.1 - 1.2e-05 24.8 1.5 4.6e-05 22.9 0.5 2.3 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KFP05119.1 - 0.069 11.2 6.6 1.4 6.9 0.2 3.0 2 1 0 3 3 3 0 Nucleoporin Nup120/160 CNH PF00780.17 KFP05120.1 - 1.5e-65 221.3 0.2 3.2e-65 220.2 0.1 1.6 1 0 0 1 1 1 1 CNH domain Rap_GAP PF02145.10 KFP05120.1 - 6.1e-64 214.8 0.1 1.1e-63 214.0 0.1 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Laminin_G_3 PF13385.1 KFP05121.1 - 2.5e-25 89.5 0.0 4.6e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sushi PF00084.15 KFP05121.1 - 2.4e-15 56.6 60.6 3.9e-07 30.3 3.4 8.7 8 2 1 9 9 9 4 Sushi domain (SCR repeat) Notch PF00066.12 KFP05121.1 - 2.1e-11 43.8 38.6 2.8e-07 30.6 2.1 6.7 8 0 0 8 8 5 3 LNR domain Peptidase_M43 PF05572.8 KFP05121.1 - 2.2e-08 33.8 0.1 7.6e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KFP05121.1 - 0.0036 17.8 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like fn3 PF00041.16 KFP05121.1 - 0.0039 17.2 0.9 3.3 7.9 0.0 3.4 3 0 0 3 3 3 1 Fibronectin type III domain Reprolysin_4 PF13583.1 KFP05121.1 - 0.0074 15.8 0.1 0.025 14.1 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP05121.1 - 0.014 15.5 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Laminin_G_2 PF02210.19 KFP05121.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain Peptidase_M57 PF12388.3 KFP05121.1 - 0.12 11.6 0.4 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 KFP05121.1 - 0.16 11.7 0.1 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Matrixin FXa_inhibition PF14670.1 KFP05122.1 - 1.2e-10 41.3 43.3 8.2e-10 38.6 2.8 4.1 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site MACPF PF01823.14 KFP05122.1 - 2.1e-06 27.5 1.0 4.3e-06 26.5 0.2 1.8 2 0 0 2 2 2 1 MAC/Perforin domain fn3 PF00041.16 KFP05122.1 - 0.0087 16.1 0.0 0.029 14.5 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain cEGF PF12662.2 KFP05122.1 - 4.3 7.0 10.7 0.35 10.5 0.5 3.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like NHL PF01436.16 KFP05123.1 - 5.7e-30 101.7 1.7 2.5e-05 23.9 0.1 5.8 6 0 0 6 6 6 5 NHL repeat zf-RING_UBOX PF13445.1 KFP05123.1 - 1.1e-11 44.2 8.2 3.1e-11 42.8 5.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFP05123.1 - 6.1e-09 35.7 10.2 6.1e-09 35.7 7.1 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP05123.1 - 1.9e-08 33.9 8.8 1.9e-08 33.9 6.1 3.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFP05123.1 - 5e-07 29.3 9.2 5e-07 29.3 6.4 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFP05123.1 - 2.2e-06 27.2 10.4 2.2e-06 27.2 7.2 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 KFP05123.1 - 2.8e-05 23.9 3.8 2.8e-05 23.9 2.6 3.3 3 1 0 3 3 3 1 B-box zinc finger zf-C3HC4_4 PF15227.1 KFP05123.1 - 4.5e-05 23.2 9.1 4.5e-05 23.2 6.3 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 KFP05123.1 - 9.5e-05 22.1 0.8 9.5e-05 22.1 0.6 2.4 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 KFP05123.1 - 0.00021 20.8 5.6 0.00021 20.8 3.9 2.9 4 0 0 4 4 3 1 RING/Ubox like zinc-binding domain SGL PF08450.7 KFP05123.1 - 0.0026 17.1 0.0 18 4.6 0.0 3.9 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region FYVE PF01363.16 KFP05123.1 - 0.0091 15.8 2.4 0.0091 15.8 1.6 3.0 3 1 0 3 3 3 2 FYVE zinc finger LRR_8 PF13855.1 KFP05124.1 - 1.2e-55 185.1 54.4 7.9e-13 47.9 1.7 10.1 5 3 3 9 9 9 8 Leucine rich repeat TIR PF01582.15 KFP05124.1 - 1.4e-28 99.0 0.0 2.8e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain LRR_4 PF12799.2 KFP05124.1 - 3e-26 90.5 56.7 5.9e-07 28.9 0.6 11.4 5 3 8 13 13 13 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP05124.1 - 6.2e-16 55.9 54.2 0.8 9.9 0.0 16.7 17 1 1 18 18 18 8 Leucine Rich Repeat TIR_2 PF13676.1 KFP05124.1 - 3.4e-09 36.7 0.0 1e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 TIR domain LRR_6 PF13516.1 KFP05124.1 - 1.3e-08 34.0 54.3 0.21 11.7 0.6 14.3 15 1 1 16 16 16 7 Leucine Rich repeat LRR_7 PF13504.1 KFP05124.1 - 3.5e-06 26.3 46.5 12 6.6 0.0 14.7 15 0 0 15 15 15 1 Leucine rich repeat LRR_9 PF14580.1 KFP05124.1 - 0.0009 18.8 10.9 0.037 13.5 0.2 3.7 3 1 1 4 4 4 2 Leucine-rich repeat Col_cuticle_N PF01484.12 KFP05124.1 - 2.4 7.8 7.0 2.2 8.0 3.3 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Yae1_N PF09811.4 KFP05125.1 - 1.8e-11 43.3 31.1 2.3 7.8 21.6 3.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Biliv-reduc_cat PF09166.5 KFP05127.1 - 2e-54 182.5 0.0 3e-54 181.9 0.0 1.3 1 0 0 1 1 1 1 Biliverdin reductase, catalytic GFO_IDH_MocA PF01408.17 KFP05127.1 - 6.2e-18 65.4 0.1 1.5e-17 64.1 0.1 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HECT PF00632.20 KFP05128.1 - 1e-90 304.1 0.0 1.5e-90 303.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFP05128.1 - 5.1e-17 61.4 0.4 1.6e-09 37.4 0.4 2.8 2 0 0 2 2 2 2 WW domain C2 PF00168.25 KFP05128.1 - 9.8e-10 38.1 0.0 2.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Keratin_B2_2 PF13885.1 KFP05128.1 - 0.21 11.3 22.3 0.74 9.5 15.5 2.0 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein RFXA_RFXANK_bdg PF15289.1 KFP05128.1 - 1.2 9.3 4.0 0.59 10.3 0.0 2.5 3 0 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain Ribosomal_L32p PF01783.18 KFP05129.1 - 1.9e-08 34.3 6.9 3.2e-08 33.6 4.8 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.10 KFP05129.1 - 0.0012 18.2 0.7 0.0022 17.3 0.5 1.4 1 0 0 1 1 1 1 RecR protein zf-UBR PF02207.15 KFP05129.1 - 0.016 14.9 0.6 0.022 14.4 0.4 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.2 KFP05129.1 - 0.049 13.4 1.9 0.1 12.4 1.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Proteasome PF00227.21 KFP05130.1 - 6.2e-60 201.7 0.0 8.3e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFP05130.1 - 2.2e-06 26.8 0.1 3.7e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PBP_dimer PF03717.10 KFP05130.1 - 0.014 15.4 0.0 2.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain DUF1308 PF07000.6 KFP05131.1 - 3.2e-120 401.0 0.1 3.7e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Yae1_N PF09811.4 KFP05134.1 - 3.4e-13 48.8 69.8 1.5e+04 -35.8 48.4 6.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Robl_LC7 PF03259.12 KFP05135.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Roadblock/LC7 domain MFS_1 PF07690.11 KFP05136.1 - 5.5e-33 114.1 37.0 1.2e-18 66.9 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFP05136.1 - 0.036 13.8 6.7 1.7 8.4 0.5 4.0 4 0 0 4 4 4 0 MFS_1 like family SPOC PF07744.8 KFP05137.1 - 1.3e-30 106.3 0.0 2.2e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.17 KFP05137.1 - 2.8e-19 68.5 0.0 1.9e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05137.1 - 2.7e-17 62.4 0.0 4.6e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP05137.1 - 1.1e-10 41.1 0.0 3.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFP05137.1 - 2.7e-07 30.2 0.0 0.00047 19.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFP05137.1 - 7.3e-05 22.5 0.0 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Ion_trans PF00520.26 KFP05138.1 - 2.9e-31 108.3 10.0 2.9e-31 108.3 6.9 1.5 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP05138.1 - 1.7e-29 101.8 0.0 3.8e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP05138.1 - 7.4e-10 38.4 4.8 7.4e-10 38.4 3.3 2.5 2 0 0 2 2 2 1 Ion channel DUF202 PF02656.10 KFP05138.1 - 0.93 9.7 7.3 34 4.7 0.0 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF202) PKD_channel PF08016.7 KFP05138.1 - 1 7.6 8.1 0.096 11.0 1.8 1.8 1 1 1 2 2 2 0 Polycystin cation channel SNF PF00209.13 KFP05139.1 - 2.6e-222 738.9 34.3 3.2e-222 738.6 23.7 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Homeobox PF00046.24 KFP05140.1 - 4.8e-25 86.9 7.2 5.7e-25 86.7 5.0 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP05140.1 - 0.00014 21.4 0.1 0.00023 20.7 0.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain DUF3402 PF11882.3 KFP05141.1 - 2.5e-134 448.3 0.4 4e-134 447.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KFP05141.1 - 6.9e-68 228.6 0.0 4.2e-62 209.6 0.0 2.2 2 0 0 2 2 2 2 N1221-like protein AdoHcyase PF05221.12 KFP05142.1 - 1.1e-26 93.3 0.7 5.1e-18 64.9 0.0 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase GST_C PF00043.20 KFP05143.1 - 1.3e-15 57.1 0.2 2e-15 56.5 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFP05143.1 - 6.1e-07 29.8 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFP05143.1 - 4.1e-06 26.8 0.0 9.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFP05143.1 - 0.001 18.8 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFP05143.1 - 0.013 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain A_deaminase PF00962.17 KFP05144.1 - 3.3e-119 397.6 1.7 4.8e-119 397.1 1.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase G-alpha PF00503.15 KFP05145.1 - 1.6e-127 425.3 2.5 1.9e-127 425.2 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP05145.1 - 2.8e-14 52.7 0.4 5.2e-13 48.6 0.0 2.7 2 1 1 3 3 3 1 ADP-ribosylation factor family Miro PF08477.8 KFP05145.1 - 0.0013 19.2 0.8 1 9.8 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein Proteasome PF00227.21 KFP05146.1 - 2.2e-56 190.1 0.0 2.7e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFP05146.1 - 3.8e-12 45.2 0.0 6.5e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cytochrom_C552 PF02335.10 KFP05147.1 - 0.03 13.0 0.2 0.036 12.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c552 Shisa PF13908.1 KFP05148.1 - 1.6e-11 44.7 11.1 1.7e-11 44.6 7.7 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Tropomodulin PF03250.9 KFP05149.1 - 8.2e-10 38.3 1.5 8.2e-10 38.3 1.0 2.8 3 1 0 3 3 3 1 Tropomodulin WH2 PF02205.15 KFP05149.1 - 0.00031 20.2 0.4 0.00031 20.2 0.3 2.1 2 0 0 2 2 2 1 WH2 motif Tim17 PF02466.14 KFP05150.1 - 8.2e-35 119.6 4.5 9.8e-35 119.3 3.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HlyIII PF03006.15 KFP05151.1 - 5.9e-69 231.8 21.3 7.2e-69 231.5 14.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4405 PF14358.1 KFP05151.1 - 0.0069 16.4 2.2 0.0069 16.4 1.5 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF4405) NfeD PF01957.13 KFP05151.1 - 0.056 13.5 0.1 0.056 13.5 0.1 3.1 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF962 PF06127.6 KFP05151.1 - 2.6 7.9 9.6 0.061 13.2 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF4131 PF13567.1 KFP05151.1 - 4.8 6.5 20.0 0.61 9.4 3.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) UQ_con PF00179.21 KFP05152.1 - 6.8e-37 126.0 0.0 7.5e-37 125.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KFP05152.1 - 0.003 17.2 0.1 0.0056 16.3 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KFP05152.1 - 0.0034 17.2 0.1 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 KFP05152.1 - 0.0063 16.2 0.0 0.0073 16.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Frag1 PF10277.4 KFP05153.1 - 5.3e-45 153.5 18.7 6.2e-45 153.3 13.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Bac_export_2 PF01312.14 KFP05153.1 - 0.35 9.7 7.0 0.34 9.7 4.4 1.5 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF3989 PF13150.1 KFP05153.1 - 1 8.8 5.4 0.91 9.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) CDP-OH_P_transf PF01066.16 KFP05154.1 - 2.2e-20 72.8 6.8 2.2e-20 72.8 4.7 3.0 2 1 1 3 3 3 1 CDP-alcohol phosphatidyltransferase DENN PF02141.16 KFP05155.1 - 7.1e-57 192.1 2.1 1.3e-56 191.2 1.4 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFP05155.1 - 1.4e-25 88.9 1.0 2.9e-25 88.0 0.1 1.9 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 KFP05155.1 - 5e-18 64.9 1.3 9.1e-18 64.0 0.9 1.5 1 0 0 1 1 1 1 dDENN domain HPD PF05044.7 KFP05155.1 - 0.016 14.8 0.1 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Homeo-prospero domain 7tm_6 PF02949.15 KFP05155.1 - 0.053 12.3 0.1 0.083 11.7 0.1 1.4 1 0 0 1 1 1 0 7tm Odorant receptor I-set PF07679.11 KFP05156.1 - 1.8e-33 114.2 0.0 1.2e-16 60.3 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain fn3 PF00041.16 KFP05156.1 - 1.2e-20 73.4 0.0 1.4e-14 54.0 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ig_2 PF13895.1 KFP05156.1 - 9.2e-15 54.5 0.0 4.1e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP05156.1 - 1.6e-06 28.1 0.3 0.0019 18.3 0.1 2.6 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.7 KFP05156.1 - 2.1e-06 27.5 0.1 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Herpes_gI PF01688.12 KFP05156.1 - 0.00072 18.7 0.0 0.0091 15.1 0.0 2.1 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein I C1-set PF07654.10 KFP05156.1 - 0.0014 18.6 0.4 1.8 8.6 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin C1-set domain Ig_3 PF13927.1 KFP05156.1 - 0.002 18.5 0.1 0.39 11.2 0.0 3.4 2 1 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP05156.1 - 0.004 17.0 0.0 1.5 8.7 0.0 2.9 2 1 0 2 2 2 1 Immunoglobulin V-set domain HTH_27 PF13463.1 KFP05156.1 - 0.098 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF3484 PF11983.3 KFP05156.1 - 1.4 9.7 5.1 5.7 7.8 0.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3484) FAP PF07174.6 KFP05156.1 - 6.9 5.8 26.7 11 5.1 18.5 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) 7tm_1 PF00001.16 KFP05157.1 - 5.4e-53 179.7 13.8 6.1e-53 179.5 9.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05157.1 - 1.3e-10 40.9 10.8 7.6e-10 38.3 7.5 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP05157.1 - 9.6e-05 21.6 4.8 9.6e-05 21.6 3.3 2.3 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx CcmH PF03918.9 KFP05157.1 - 0.044 12.7 0.6 0.12 11.3 0.0 2.0 3 0 0 3 3 3 0 Cytochrome C biogenesis protein UPF0182 PF03699.8 KFP05157.1 - 0.13 10.1 4.1 0.15 9.9 2.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF3382 PF11862.3 KFP05157.1 - 0.16 11.8 7.1 4.9 7.1 0.1 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF3382) Basic PF01586.11 KFP05158.1 - 7.5e-27 93.8 0.2 1.7e-26 92.7 0.1 1.6 2 0 0 2 2 2 1 Myogenic Basic domain HLH PF00010.21 KFP05158.1 - 4.5e-13 48.6 5.5 9.1e-13 47.6 3.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3080 PF11279.3 KFP05158.1 - 0.021 13.9 0.3 0.03 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) SAM_2 PF07647.12 KFP05159.1 - 2.2e-25 88.2 1.2 5.1e-11 42.2 0.1 3.9 3 0 0 3 3 3 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP05159.1 - 5.9e-25 87.2 5.7 1.6e-12 47.4 0.1 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) DUF4279 PF14106.1 KFP05159.1 - 0.069 13.0 2.1 0.27 11.1 0.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) TPR_MLP1_2 PF07926.7 KFP05159.1 - 0.6 9.8 52.0 64 3.2 4.6 5.7 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein F-box-like PF12937.2 KFP05160.1 - 0.095 12.4 2.3 0.2 11.3 1.6 1.5 1 0 0 1 1 1 0 F-box-like Tmemb_9 PF05434.6 KFP05161.1 - 4.9e-67 224.3 0.4 7e-67 223.8 0.3 1.2 1 0 0 1 1 1 1 TMEM9 Arif-1 PF06770.6 KFP05161.1 - 0.12 11.7 1.6 0.2 11.0 1.1 1.3 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) fn3 PF00041.16 KFP05162.1 - 2.2e-60 200.7 12.6 9.4e-17 60.9 0.2 5.2 5 0 0 5 5 5 4 Fibronectin type III domain I-set PF07679.11 KFP05162.1 - 1.8e-54 181.5 0.6 7.2e-17 61.0 0.0 7.2 8 1 1 9 9 9 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05162.1 - 1.5e-18 66.6 0.0 6.2e-08 32.6 0.0 4.7 4 0 0 4 4 4 2 Immunoglobulin domain Tissue_fac PF01108.12 KFP05162.1 - 7.8e-11 41.6 0.1 0.081 12.6 0.0 4.4 4 0 0 4 4 4 4 Tissue factor Receptor_2B4 PF11465.3 KFP05162.1 - 1.6e-08 34.4 0.0 0.0046 16.8 0.0 3.8 3 0 0 3 3 3 2 Natural killer cell receptor 2B4 V-set PF07686.12 KFP05162.1 - 4.9e-08 32.8 1.8 0.054 13.4 0.0 5.5 3 3 1 4 4 4 1 Immunoglobulin V-set domain ig PF00047.20 KFP05162.1 - 1.2e-06 28.5 3.0 0.18 11.9 0.0 4.6 4 1 0 4 4 4 2 Immunoglobulin domain C2-set_2 PF08205.7 KFP05162.1 - 5.8e-06 26.1 0.3 0.16 11.8 0.0 3.5 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain SusE PF14292.1 KFP05162.1 - 2.9e-05 23.8 3.3 6 6.7 0.0 5.1 4 2 1 5 5 5 1 SusE outer membrane protein Ig_3 PF13927.1 KFP05162.1 - 3.3e-05 24.2 9.6 0.0047 17.4 0.4 6.0 6 3 1 7 7 7 1 Immunoglobulin domain ChitinaseA_N PF08329.5 KFP05162.1 - 0.0036 17.0 1.0 1.7 8.3 0.0 2.9 2 0 0 2 2 2 2 Chitinase A, N-terminal domain Herpes_gE PF02480.11 KFP05162.1 - 0.0082 14.4 0.0 0.11 10.7 0.0 2.6 3 0 0 3 3 3 1 Alphaherpesvirus glycoprotein E Qn_am_d_aII PF14930.1 KFP05162.1 - 0.097 12.6 0.4 12 5.9 0.0 3.1 3 0 0 3 3 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Reeler PF02014.11 KFP05162.1 - 0.098 12.9 2.1 38 4.5 0.0 4.6 5 0 0 5 5 5 0 Reeler domain Arm PF00514.18 KFP05163.1 - 5.1e-30 102.2 6.3 5.1e-10 38.8 0.0 7.6 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP05163.1 - 6.8e-07 29.4 0.2 0.0036 17.5 0.0 3.1 2 2 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KFP05163.1 - 8.2e-05 22.9 0.8 0.43 11.1 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 KFP05163.1 - 0.00052 19.8 0.1 0.62 10.2 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Adaptin_N PF01602.15 KFP05163.1 - 0.038 12.3 0.8 4.1 5.6 0.1 2.5 1 1 2 3 3 3 0 Adaptin N terminal region DUF383 PF04063.9 KFP05163.1 - 0.064 12.7 0.5 3.8 7.0 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF383) Mo25 PF08569.6 KFP05163.1 - 0.099 11.6 0.0 0.44 9.5 0.0 1.9 2 0 0 2 2 2 0 Mo25-like Arm_2 PF04826.8 KFP05163.1 - 0.099 11.7 1.5 0.8 8.7 0.1 2.6 2 1 1 3 3 3 0 Armadillo-like V-ATPase_H_C PF11698.3 KFP05163.1 - 0.11 12.4 0.0 0.4 10.5 0.0 1.9 1 0 0 1 1 1 0 V-ATPase subunit H Troponin PF00992.15 KFP05164.1 - 5.3e-42 143.0 39.9 2.8e-39 134.1 22.4 2.0 1 1 1 2 2 2 2 Troponin NBP1 PF08537.5 KFP05164.1 - 2.9 6.9 25.6 0.041 13.0 8.5 2.4 2 1 0 2 2 2 0 Fungal Nap binding protein NBP1 Troponin PF00992.15 KFP05165.1 - 3e-50 169.6 6.8 4.1e-50 169.2 4.7 1.2 1 0 0 1 1 1 1 Troponin IFT20 PF14931.1 KFP05165.1 - 0.031 14.1 4.6 0.22 11.4 0.4 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 XkdW PF09636.5 KFP05165.1 - 0.048 13.5 1.5 0.21 11.4 1.0 2.1 1 1 0 1 1 1 0 XkdW protein ADIP PF11559.3 KFP05165.1 - 0.051 13.4 2.6 0.14 12.0 1.5 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 KFP05165.1 - 5.8 6.6 9.3 9.5 5.9 4.1 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PH PF00169.24 KFP05166.1 - 1.4e-05 25.1 0.0 1.9e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 PH domain FAM194 PF14977.1 KFP05166.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 FAM194 protein LIM PF00412.17 KFP05167.1 - 2.6e-30 104.2 25.7 5e-17 61.7 3.7 2.1 2 0 0 2 2 2 2 LIM domain PHF5 PF03660.9 KFP05167.1 - 0.11 12.5 13.0 0.15 12.1 3.2 2.2 2 0 0 2 2 2 0 PHF5-like protein DZR PF12773.2 KFP05167.1 - 0.44 10.3 23.6 0.25 11.2 4.4 4.0 2 2 0 2 2 2 0 Double zinc ribbon zf-DNA_Pol PF08996.5 KFP05167.1 - 1.8 7.8 14.5 0.55 9.5 0.3 2.3 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger E6 PF00518.12 KFP05167.1 - 2 8.8 10.0 2.3 8.5 0.1 2.8 2 1 0 2 2 2 0 Early Protein (E6) zf-MYND PF01753.13 KFP05167.1 - 4.4 7.2 25.0 2.2 8.2 1.1 4.3 3 1 1 4 4 4 0 MYND finger zf-C3HC4_2 PF13923.1 KFP05167.1 - 5.8 7.0 23.2 0.17 11.9 0.5 4.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF4428 PF14471.1 KFP05167.1 - 6.5 6.5 16.5 0.99 9.2 1.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zf-TFIIB PF13453.1 KFP05167.1 - 7.6 5.8 17.8 0.93 8.7 0.4 3.8 4 0 0 4 4 4 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.5 KFP05167.1 - 8.2 6.4 21.9 0.21 11.5 2.7 4.0 4 1 0 4 4 4 0 Zinc ribbon domain C2 PF00168.25 KFP05168.1 - 4.7e-54 180.1 0.4 1.4e-26 92.1 0.1 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 KFP05168.1 - 0.00016 21.1 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 CEP76 C2 domain DOCK-C2 PF14429.1 KFP05168.1 - 0.00021 20.9 0.4 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins FAM176 PF14851.1 KFP05168.1 - 0.0047 16.6 0.7 0.0085 15.7 0.5 1.4 1 0 0 1 1 1 1 FAM176 family DUF1510 PF07423.6 KFP05168.1 - 0.0097 15.3 0.1 0.028 13.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Orthopox_A36R PF05950.6 KFP05168.1 - 0.041 13.8 0.1 0.074 12.9 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Trypan_PARP PF05887.6 KFP05168.1 - 0.042 13.6 0.1 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EphA2_TM PF14575.1 KFP05168.1 - 0.048 14.0 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0561 PF10573.4 KFP05168.1 - 0.06 13.2 0.2 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 TMEM52 PF14979.1 KFP05168.1 - 0.13 12.2 3.6 0.23 11.3 2.5 1.3 1 0 0 1 1 1 0 Transmembrane 52 Prothymosin PF03247.9 KFP05168.1 - 0.62 10.2 15.7 0.11 12.6 6.3 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family Peptidase_M1 PF01433.15 KFP05169.1 - 1.2e-67 228.6 0.0 1.5e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFP05169.1 - 2.1e-40 137.5 0.5 3.3e-40 136.9 0.3 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFP05169.1 - 7.6e-19 68.0 0.0 1.9e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Kelch_3 PF13415.1 KFP05170.1 - 5.2e-40 134.7 5.2 3e-08 33.6 0.0 7.6 8 0 0 8 8 8 7 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP05170.1 - 3.3e-37 126.0 5.0 1.6e-09 37.3 0.0 5.4 4 1 1 5 5 5 5 Galactose oxidase, central domain BTB PF00651.26 KFP05170.1 - 8.7e-34 115.8 5.4 6.9e-21 74.3 0.0 4.8 2 2 2 4 4 4 4 BTB/POZ domain Kelch_1 PF01344.20 KFP05170.1 - 9.3e-33 111.5 1.6 2.3e-08 33.4 0.0 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 KFP05170.1 - 9.8e-33 111.5 6.5 7.9e-08 32.0 0.3 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 KFP05170.1 - 5.7e-27 92.7 7.2 2.5e-09 36.8 0.0 5.6 4 1 1 5 5 5 5 Kelch motif Kelch_2 PF07646.10 KFP05170.1 - 1.9e-19 68.5 2.0 1.5e-06 27.7 0.0 5.3 5 0 0 5 5 5 3 Kelch motif BACK PF07707.10 KFP05170.1 - 0.0024 17.6 12.2 0.0053 16.5 0.7 4.7 5 0 0 5 5 5 1 BTB And C-terminal Kelch RAG2 PF03089.9 KFP05170.1 - 0.0088 14.8 0.1 0.15 10.7 0.0 2.6 3 0 0 3 3 3 1 Recombination activating protein 2 ROF PF07073.7 KFP05170.1 - 0.23 11.5 6.5 2.5 8.1 0.6 2.4 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) PLU-1 PF08429.6 KFP05171.1 - 1.6e-97 326.4 15.3 1.7e-92 309.8 4.1 3.6 3 0 0 3 3 3 3 PLU-1-like protein JmjC PF02373.17 KFP05171.1 - 2.1e-44 150.4 0.7 4.8e-44 149.2 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 KFP05171.1 - 1.2e-25 88.9 37.8 2.8e-11 42.9 2.8 4.1 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 KFP05171.1 - 1.3e-24 85.8 0.0 4.2e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 KFP05171.1 - 2.5e-18 65.8 11.4 1.5e-17 63.3 7.9 2.5 1 0 0 1 1 1 1 C5HC2 zinc finger Lipoprotein_20 PF13942.1 KFP05171.1 - 0.0015 18.0 1.0 0.074 12.5 0.0 2.7 2 0 0 2 2 2 1 YfhG lipoprotein Tubulin PF00091.20 KFP05172.1 - 9.7e-70 234.7 0.0 1.2e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFP05172.1 - 1.9e-47 160.4 0.0 3.6e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFP05172.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Trypsin PF00089.21 KFP05174.1 - 1.4e-67 227.4 0.3 1.6e-67 227.3 0.2 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP05174.1 - 0.0011 18.3 0.1 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF316 PF03761.10 KFP05174.1 - 0.0024 17.2 0.0 0.56 9.5 0.0 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF316) Trypsin_2 PF13365.1 KFP05174.1 - 0.024 14.6 0.0 0.05 13.5 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain Ion_trans PF00520.26 KFP05175.1 - 1.2e-211 697.1 80.3 2e-62 210.0 10.3 4.3 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.6 KFP05175.1 - 2.9e-16 58.3 1.3 1.1e-15 56.5 0.9 2.1 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.7 KFP05175.1 - 6.7e-09 34.6 29.6 4.3e-08 32.0 6.0 8.4 7 3 1 8 8 8 3 Polycystin cation channel Kinesin PF00225.18 KFP05176.1 - 3.8e-103 344.7 0.0 3.8e-103 344.7 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain WD40 PF00400.27 KFP05176.1 - 3.4e-40 134.5 9.6 4.5e-06 26.3 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Ets PF00178.17 KFP05177.1 - 4.5e-29 100.4 2.1 9.5e-29 99.3 1.4 1.6 1 0 0 1 1 1 1 Ets-domain SAM_PNT PF02198.11 KFP05177.1 - 4.1e-18 64.9 0.0 1.8e-17 62.8 0.0 2.1 3 0 0 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain AT_hook PF02178.14 KFP05177.1 - 0.29 10.9 6.0 0.74 9.6 4.1 1.7 1 0 0 1 1 1 0 AT hook motif 7tm_1 PF00001.16 KFP05178.1 - 9.1e-27 93.8 14.0 1.3e-26 93.3 9.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PDR_CDR PF06422.7 KFP05178.1 - 0.024 14.3 4.4 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 CDR ABC transporter Arf PF00025.16 KFP05179.1 - 2.2e-39 134.4 0.0 2.6e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP05179.1 - 5.1e-14 51.9 0.0 5.6e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP05179.1 - 1.2e-06 29.0 0.0 4.4e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KFP05179.1 - 4.7e-06 25.9 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFP05179.1 - 1.6e-05 23.7 0.0 2.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFP05179.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP05179.1 - 0.0023 17.1 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Y_phosphatase PF00102.22 KFP05180.1 - 1.5e-74 250.2 0.0 1.9e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP05180.1 - 5.8e-05 22.6 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP05180.1 - 0.0039 17.4 0.0 0.0093 16.2 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family LRR_8 PF13855.1 KFP05181.1 - 4.4e-73 240.9 47.0 2.9e-13 49.3 0.4 8.0 2 2 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFP05181.1 - 5.3e-41 137.6 29.1 7e-09 35.1 0.0 8.8 3 3 2 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP05181.1 - 1e-26 88.8 29.0 0.046 13.7 0.1 15.0 15 1 1 16 16 16 9 Leucine Rich Repeat LRR_5 PF13306.1 KFP05181.1 - 3.8e-21 75.1 0.0 2.3e-08 33.7 0.0 4.0 1 1 2 4 4 4 4 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFP05181.1 - 1.1e-13 49.6 25.1 1.7 8.9 0.1 13.1 12 2 2 14 14 14 4 Leucine Rich repeat LRR_7 PF13504.1 KFP05181.1 - 5.2e-13 46.9 30.1 0.22 11.8 0.1 12.9 14 0 0 14 14 14 4 Leucine rich repeat LRR_9 PF14580.1 KFP05181.1 - 4.5e-09 36.0 3.5 0.09 12.3 0.1 5.0 1 1 6 7 7 7 6 Leucine-rich repeat 7tm_1 PF00001.16 KFP05181.1 - 6.6e-09 35.2 13.1 1e-08 34.6 9.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.1 KFP05183.1 - 6e-50 166.8 34.5 3.5e-13 49.1 1.7 6.5 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 KFP05183.1 - 8.8e-28 95.4 41.9 5.5e-06 25.8 0.3 8.1 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP05183.1 - 1.7e-16 60.1 0.0 4e-08 33.0 0.0 2.8 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) I-set PF07679.11 KFP05183.1 - 8.8e-14 51.1 0.0 1.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFP05183.1 - 3e-12 44.7 39.0 0.07 13.1 0.1 12.5 13 0 0 13 13 13 5 Leucine Rich Repeat LRR_9 PF14580.1 KFP05183.1 - 3.6e-09 36.4 10.8 0.013 15.0 0.9 4.6 1 1 4 5 5 5 3 Leucine-rich repeat Ig_2 PF13895.1 KFP05183.1 - 5e-08 32.9 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_6 PF13516.1 KFP05183.1 - 1.2e-07 31.0 29.2 0.37 10.9 0.1 10.9 9 3 3 12 12 12 3 Leucine Rich repeat LRR_7 PF13504.1 KFP05183.1 - 2.2e-07 29.9 32.1 0.41 11.0 0.1 11.8 11 1 1 12 12 12 1 Leucine rich repeat Ig_3 PF13927.1 KFP05183.1 - 3e-05 24.4 0.0 9.1e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP05183.1 - 0.00025 20.9 0.0 0.00082 19.2 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain SWIB PF02201.13 KFP05184.1 - 2.5e-10 39.8 0.0 4.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-C3HC4_3 PF13920.1 KFP05184.1 - 1.7e-08 33.9 6.9 1.7e-08 33.9 4.8 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 KFP05184.1 - 1.8e-06 26.9 8.4 1.8e-06 26.9 5.8 2.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.1 KFP05184.1 - 0.0003 20.7 7.4 0.0003 20.7 5.1 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF596 PF04591.7 KFP05184.1 - 0.11 12.4 0.0 26 4.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF596 DZR PF12773.2 KFP05184.1 - 0.12 12.1 17.8 1.8 8.4 1.7 2.9 2 0 0 2 2 2 0 Double zinc ribbon PI3_PI4_kinase PF00454.22 KFP05186.1 - 5.3e-53 179.9 0.2 9.5e-53 179.0 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFP05186.1 - 1.2e-36 125.6 0.3 2.5e-36 124.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 KFP05186.1 - 3e-29 101.6 0.0 7.4e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 KFP05186.1 - 1.1e-25 89.6 0.0 4.1e-25 87.7 0.1 2.0 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain C2 PF00168.25 KFP05186.1 - 4e-15 55.4 0.0 8.9e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain PX PF00787.19 KFP05186.1 - 0.0002 21.1 0.0 0.0033 17.2 0.0 2.6 1 1 0 1 1 1 1 PX domain DUF4135 PF13575.1 KFP05186.1 - 0.076 12.0 0.1 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PP1c_bdg PF10488.4 KFP05187.1 - 4.2e-74 249.5 22.7 3e-73 246.6 15.8 1.9 1 1 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region DCA16 PF15349.1 KFP05187.1 - 0.017 14.4 1.2 0.027 13.8 0.8 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 VEFS-Box PF09733.4 KFP05187.1 - 8.3 6.0 9.7 6 6.5 1.0 2.3 2 0 0 2 2 2 0 VEFS-Box of polycomb protein PH PF00169.24 KFP05188.1 - 1.6e-10 41.1 1.1 1e-09 38.5 0.8 2.3 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP05188.1 - 1.8e-07 31.3 0.1 9.5e-07 29.0 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain AAA_13 PF13166.1 KFP05188.1 - 0.13 10.6 5.5 0.28 9.6 3.8 1.4 1 0 0 1 1 1 0 AAA domain Got1 PF04178.7 KFP05189.1 - 1.3e-16 60.7 20.3 1.6e-16 60.4 14.1 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Asp PF00026.18 KFP05190.1 - 2.5e-111 371.9 0.0 2.9e-111 371.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFP05190.1 - 1.8e-06 28.0 0.0 3.8e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 KFP05190.1 - 9.3e-06 25.2 0.2 1.7e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.1 KFP05190.1 - 0.0003 20.3 0.0 0.0014 18.1 0.0 2.1 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Kelch_6 PF13964.1 KFP05190.1 - 0.11 12.6 1.2 16 5.8 0.1 2.6 2 0 0 2 2 2 0 Kelch motif Choline_kinase PF01633.15 KFP05191.1 - 6.5e-58 195.7 0.0 1e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFP05191.1 - 1.8e-13 50.8 0.0 2.7e-13 50.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFP05191.1 - 5.3e-05 22.4 0.4 0.00016 20.8 0.3 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase Caps_assemb_Wzi PF14052.1 KFP05191.1 - 0.0011 17.9 0.6 0.0014 17.5 0.4 1.1 1 0 0 1 1 1 1 Capsule assembly protein Wzi LSM PF01423.17 KFP05192.1 - 9.2e-17 60.3 0.1 1e-16 60.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain E1-E2_ATPase PF00122.15 KFP05193.1 - 1.3e-58 197.7 1.7 3.2e-58 196.5 1.2 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFP05193.1 - 6.7e-44 149.5 3.7 5.9e-43 146.4 1.1 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.3 KFP05193.1 - 1.1e-28 99.4 0.0 2.7e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.21 KFP05193.1 - 1.2e-25 91.2 0.0 2.6e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP05193.1 - 1.7e-17 63.1 0.0 4.1e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFP05193.1 - 2.4e-16 58.9 0.0 8.7e-16 57.1 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFP05193.1 - 1.5e-13 51.3 0.0 3.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFP05193.1 - 9.6e-07 28.6 0.2 0.00018 21.1 0.2 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase LRR_8 PF13855.1 KFP05194.1 - 1.5e-32 111.1 34.5 4.1e-13 48.8 5.1 6.9 3 2 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 KFP05194.1 - 3.6e-31 106.2 34.4 3.1e-08 33.0 2.2 8.1 5 3 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP05194.1 - 8.6e-20 67.7 32.8 0.017 15.0 0.0 11.3 9 2 2 11 11 11 7 Leucine Rich Repeat LRR_7 PF13504.1 KFP05194.1 - 1.9e-11 42.1 25.2 0.38 11.1 0.0 10.6 11 0 0 11 11 11 3 Leucine rich repeat LRR_6 PF13516.1 KFP05194.1 - 2.7e-10 39.2 29.1 0.17 12.0 0.0 10.1 10 1 1 11 11 11 3 Leucine Rich repeat LRRNT PF01462.13 KFP05194.1 - 4.5e-06 25.9 3.5 4.5e-06 25.9 2.5 3.4 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFP05194.1 - 0.0055 16.4 1.7 0.053 13.2 0.2 2.5 1 1 1 2 2 2 1 Leucine rich repeats (6 copies) FNIP PF05725.7 KFP05194.1 - 0.018 14.9 8.7 4.3 7.3 0.0 4.3 2 2 2 4 4 4 0 FNIP Repeat LRR_8 PF13855.1 KFP05195.1 - 2e-32 110.6 47.9 1.2e-08 34.6 0.1 6.0 2 2 6 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 KFP05195.1 - 2.6e-24 81.4 21.7 0.0099 15.7 0.0 11.3 11 0 0 11 11 11 7 Leucine Rich Repeat LRR_4 PF12799.2 KFP05195.1 - 5.2e-23 80.2 26.6 8.2e-07 28.5 0.9 7.5 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFP05195.1 - 5.5e-14 50.6 21.9 0.12 12.5 0.7 10.3 9 1 2 11 11 11 3 Leucine Rich repeat LRR_7 PF13504.1 KFP05195.1 - 9.1e-13 46.1 22.9 2.8 8.5 0.0 10.5 11 1 1 12 12 12 4 Leucine rich repeat LRR_9 PF14580.1 KFP05195.1 - 7.9e-09 35.3 1.5 0.038 13.5 0.2 3.5 1 1 2 3 3 3 3 Leucine-rich repeat LRRNT PF01462.13 KFP05195.1 - 1.3e-06 27.7 1.9 1.3e-06 27.7 1.3 3.2 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFP05195.1 - 3.8e-06 26.6 3.5 8.3e-05 22.2 0.0 2.7 2 2 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_3 PF07725.7 KFP05195.1 - 4.1 7.3 9.5 37 4.3 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat BTG PF07742.7 KFP05196.1 - 1.7e-38 130.7 0.0 2e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 BTG family Glyco_hydro_18 PF00704.23 KFP05197.1 - 4.6e-114 381.4 1.8 5.5e-114 381.1 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.19 KFP05197.1 - 1.9e-10 40.5 7.2 4e-10 39.4 5.0 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain GHL15 PF14885.1 KFP05197.1 - 0.0063 16.6 0.1 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 15 Bromo_TP PF07524.8 KFP05199.1 - 1.9e-30 104.4 0.7 5e-30 103.0 0.2 1.8 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.4 KFP05199.1 - 4.7e-25 87.3 1.1 1.3e-24 86.0 0.7 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term CENP-S PF15630.1 KFP05199.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Kinetochore component CENP-S TFIID-31kDa PF02291.10 KFP05199.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF3090 PF11290.3 KFP05199.1 - 0.028 13.9 0.3 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) CBFD_NFYB_HMF PF00808.18 KFP05199.1 - 0.036 14.1 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 KFP05199.1 - 0.094 12.6 0.3 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Cyclin_N PF00134.18 KFP05200.1 - 2.7e-28 98.0 0.4 4.2e-28 97.4 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP05200.1 - 9.9e-20 70.6 0.8 3.3e-19 68.9 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Herp-Cyclin PF09241.5 KFP05200.1 - 0.00055 20.1 0.1 0.0011 19.1 0.1 1.5 1 0 0 1 1 1 1 Herpesviridae viral cyclin K-cyclin_vir_C PF09080.5 KFP05200.1 - 0.00065 19.8 0.4 0.0011 19.1 0.3 1.3 1 0 0 1 1 1 1 K cyclin, C terminal Bystin PF05291.6 KFP05201.1 - 2.3e-141 470.0 0.4 2.8e-141 469.7 0.3 1.0 1 0 0 1 1 1 1 Bystin Med20 PF08612.6 KFP05202.1 - 3.8e-41 140.6 0.0 4.3e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex FXa_inhibition PF14670.1 KFP05203.1 - 1.6e-57 191.2 187.8 1.1e-10 41.3 6.1 12.8 12 2 0 12 12 12 9 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP05203.1 - 1.3e-35 120.6 86.9 7.1e-08 31.9 0.1 11.8 11 0 0 11 11 11 7 Complement Clr-like EGF-like GCC2_GCC3 PF07699.8 KFP05203.1 - 1.8e-29 101.0 28.4 1.5e-12 46.9 4.1 6.7 6 1 1 7 7 7 4 GCC2 and GCC3 EGF_CA PF07645.10 KFP05203.1 - 3.9e-28 97.1 95.8 4.6e-09 36.1 7.0 11.8 13 1 0 13 13 13 6 Calcium-binding EGF domain EGF_3 PF12947.2 KFP05203.1 - 7.2e-20 70.6 146.7 2.6e-10 40.0 8.2 11.8 11 0 0 11 11 11 8 EGF domain EGF PF00008.22 KFP05203.1 - 9e-20 70.2 140.6 1.6e-06 27.9 5.1 11.9 13 0 0 13 13 13 9 EGF-like domain CUB PF00431.15 KFP05203.1 - 2e-18 66.4 0.0 5.8e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 CUB domain hEGF PF12661.2 KFP05203.1 - 0.03 14.3 0.4 0.03 14.3 0.3 11.2 11 0 0 11 11 11 0 Human growth factor-like EGF PID PF00640.18 KFP05204.1 - 1.9e-31 108.9 0.4 2.5e-31 108.5 0.3 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFP05204.1 - 0.00021 21.1 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain PID_2 PF14719.1 KFP05204.1 - 0.0043 16.7 0.0 0.0052 16.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Kdo PF06293.9 KFP05204.1 - 0.069 12.2 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank PF00023.25 KFP05205.1 - 1.2e-48 160.5 15.5 1.1e-07 31.2 0.3 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFP05205.1 - 2.2e-46 156.1 8.5 2.3e-21 75.9 0.6 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP05205.1 - 2.4e-44 148.9 12.4 1.3e-11 44.6 0.0 5.8 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP05205.1 - 1.1e-42 143.0 17.7 2.9e-10 40.0 0.7 7.0 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP05205.1 - 1.5e-41 136.2 6.2 1e-06 28.3 0.0 7.0 6 0 0 6 6 6 6 Ankyrin repeat SAM_1 PF00536.25 KFP05205.1 - 5.2e-23 80.9 0.1 1.4e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP05205.1 - 6.3e-21 73.9 0.3 2.4e-13 49.7 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TAFII28 PF04719.9 KFP05206.1 - 1.4e-38 130.5 0.0 2.6e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 KFP05206.1 - 2.7e-06 27.3 0.1 5.7e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFP05206.1 - 0.003 17.6 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Cdc6_C PF09079.6 KFP05206.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal SRP_SPB PF02978.14 KFP05206.1 - 0.11 12.7 2.5 0.29 11.4 1.8 1.7 1 1 0 1 1 1 0 Signal peptide binding domain SpoU_sub_bind PF08032.7 KFP05206.1 - 0.62 10.2 2.5 15 5.8 0.3 2.8 2 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Chorein_N PF12624.2 KFP05207.1 - 5.7e-12 45.2 0.1 8.3e-10 38.2 0.0 2.8 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter zf-U1 PF06220.7 KFP05208.1 - 1.6e-20 72.3 8.3 2.1e-20 71.9 5.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KFP05208.1 - 0.011 15.7 9.9 0.079 13.1 6.8 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP05208.1 - 1 9.6 5.4 10 6.5 3.8 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type Ets PF00178.17 KFP05210.1 - 1.1e-33 115.2 0.5 1.1e-33 115.2 0.3 1.6 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFP05210.1 - 4.4e-25 87.2 0.1 8.2e-25 86.3 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain FCH PF00611.18 KFP05211.1 - 8.5e-22 77.1 0.5 8.5e-22 77.1 0.3 3.3 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFP05211.1 - 1.1e-16 60.1 0.3 2.7e-16 58.8 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP05211.1 - 1.1e-14 53.5 0.1 2.1e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP05211.1 - 1.2e-07 31.0 0.0 2.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RE_NgoFVII PF09565.5 KFP05211.1 - 0.068 12.1 2.8 0.12 11.2 1.9 1.3 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Laminin_II PF06009.7 KFP05211.1 - 1.2 8.8 8.9 0.17 11.6 2.4 2.2 2 1 0 2 2 2 0 Laminin Domain II LOH1CR12 PF10158.4 KFP05211.1 - 3.5 7.4 9.9 1.7 8.4 3.8 2.3 1 1 0 2 2 2 0 Tumour suppressor protein Phlebovirus_NSM PF07246.6 KFP05211.1 - 3.8 6.5 12.1 5.8 5.9 7.9 1.6 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Tho2 PF11262.3 KFP05211.1 - 5.4 5.9 16.0 0.91 8.5 6.4 2.6 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 NUDIX PF00293.23 KFP05213.1 - 9.7e-17 60.8 0.5 1.1e-16 60.6 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain ANF_receptor PF01094.23 KFP05214.1 - 1.5e-100 336.3 0.0 2e-100 336.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFP05214.1 - 1.7e-82 276.3 17.3 2.3e-82 275.9 12.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFP05214.1 - 1.7e-14 53.2 11.3 3.8e-14 52.1 7.8 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFP05214.1 - 2.5e-11 43.5 0.0 1.2e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 Periplasmic binding protein DUF2318 PF10080.4 KFP05214.1 - 0.0049 16.6 1.1 0.012 15.3 0.8 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) DUF336 PF03928.9 KFP05214.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF336) 7tm_1 PF00001.16 KFP05215.1 - 1.5e-52 178.3 11.4 2.1e-52 177.8 7.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.4 KFP05215.1 - 4.5e-25 87.0 3.3 1.1e-24 85.7 2.3 1.7 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.4 KFP05215.1 - 1.9e-10 40.3 11.1 1.3e-09 37.6 7.7 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 KFP05215.1 - 6.1e-08 32.1 12.9 9.8e-08 31.4 8.9 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP05215.1 - 3.3e-06 26.4 13.7 4.9e-06 25.8 9.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv TAS2R PF05296.8 KFP05215.1 - 0.33 9.7 11.5 1.7 7.4 0.8 2.2 2 0 0 2 2 2 0 Mammalian taste receptor protein (TAS2R) Git3 PF11710.3 KFP05215.1 - 0.36 10.3 8.8 1.6 8.2 6.1 2.2 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF2852 PF11014.3 KFP05215.1 - 2.2 8.2 4.5 1.4 8.9 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) MSC PF09402.5 KFP05216.1 - 6.2e-44 150.0 1.4 6.2e-44 150.0 1.0 1.3 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain Bcl-2 PF00452.14 KFP05217.1 - 2.3e-26 91.8 0.1 5.1e-26 90.7 0.0 1.6 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Bcl-2_3 PF15286.1 KFP05217.1 - 0.075 13.4 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like DUF3143 PF11341.3 KFP05217.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) TspO_MBR PF03073.10 KFP05218.1 - 8.4e-48 161.6 8.2 9.5e-48 161.4 5.7 1.0 1 0 0 1 1 1 1 TspO/MBR family Macro PF01661.16 KFP05219.1 - 3.5e-10 39.7 0.0 4.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Macro domain CBFB_NFYA PF02045.10 KFP05220.1 - 3e-28 98.1 9.3 5.2e-28 97.3 6.4 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B V-set PF07686.12 KFP05221.1 - 5.6e-10 39.1 0.5 1.8e-09 37.4 0.2 1.8 1 1 1 2 2 2 1 Immunoglobulin V-set domain Sterol-sensing PF12349.3 KFP05221.1 - 0.0074 15.7 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Brevenin PF03032.10 KFP05221.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family Herpes_gE PF02480.11 KFP05221.1 - 0.019 13.2 0.3 0.53 8.4 0.0 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Gemini_mov PF01708.11 KFP05221.1 - 0.072 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein HemY_N PF07219.8 KFP05221.1 - 0.076 12.5 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 HemY protein N-terminus Sex_peptide PF08138.6 KFP05221.1 - 0.18 11.6 0.9 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Sex peptide (SP) family MDFI PF15316.1 KFP05222.1 - 1e-59 201.4 47.3 1.1e-59 201.3 32.8 1.0 1 0 0 1 1 1 1 MyoD family inhibitor Asp PF00026.18 KFP05223.1 - 9.7e-86 287.8 0.0 1.2e-85 287.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFP05223.1 - 8.5e-07 29.0 0.0 2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFP05223.1 - 5.9e-06 25.9 0.0 1.7e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal A1_Propeptide PF07966.7 KFP05223.1 - 8.2e-06 25.4 0.2 1.9e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 A1 Propeptide Asp PF00026.18 KFP05224.1 - 1.5e-106 356.2 0.1 1.8e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease A1_Propeptide PF07966.7 KFP05224.1 - 3.8e-09 35.9 3.1 4.1e-09 35.9 0.8 2.0 2 0 0 2 2 2 1 A1 Propeptide TAXi_N PF14543.1 KFP05224.1 - 1.7e-06 28.0 0.2 6.7e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFP05224.1 - 2e-06 28.2 0.0 0.0061 17.0 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KFP05224.1 - 1.2e-05 24.8 0.0 0.00016 21.2 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal IRS PF02174.12 KFP05225.1 - 3.6e-28 97.1 0.1 7.4e-28 96.0 0.0 1.4 1 0 0 1 1 1 1 PTB domain (IRS-1 type) LIM PF00412.17 KFP05226.1 - 3e-15 56.0 18.3 1.3e-07 31.6 2.4 2.4 2 0 0 2 2 2 2 LIM domain PET PF06297.9 KFP05226.1 - 9.4e-12 44.5 0.3 1.6e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 PET Domain UCH PF00443.24 KFP05228.1 - 9e-63 211.8 3.0 1e-62 211.7 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFP05228.1 - 1.1e-21 76.6 7.6 1.1e-21 76.6 5.3 2.9 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFP05228.1 - 1e-18 67.7 9.8 9e-15 54.8 0.2 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF2955 PF11168.3 KFP05228.1 - 0.25 11.0 0.0 0.42 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) ArfGap PF01412.13 KFP05228.1 - 0.36 10.6 7.4 0.083 12.6 1.9 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Yae1_N PF09811.4 KFP05229.1 - 6.7e-05 22.3 26.1 91 2.7 18.1 2.7 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Ribosomal_L1 PF00687.16 KFP05230.1 - 5.6e-48 163.1 5.6 6.7e-48 162.9 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TetR PF13972.1 KFP05230.1 - 0.12 11.8 0.1 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor zf-H2C2_2 PF13465.1 KFP05231.1 - 3.4e-25 87.0 15.4 1.3e-10 40.9 0.3 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFP05231.1 - 1e-11 44.4 13.4 3.6e-07 30.1 0.3 3.3 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP05231.1 - 2.8e-10 39.7 8.6 3.6e-05 23.7 0.1 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-TRAF PF02176.13 KFP05231.1 - 6.7e-06 26.3 0.8 6.7e-06 26.3 0.6 1.8 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 KFP05231.1 - 0.00039 20.4 4.8 0.055 13.6 0.2 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 KFP05231.1 - 0.0077 15.8 1.6 1.4 8.6 0.6 2.8 1 1 2 3 3 3 1 Ogr/Delta-like zinc finger zf-Di19 PF05605.7 KFP05231.1 - 0.018 15.1 3.8 0.92 9.6 0.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 KFP05231.1 - 0.036 13.9 5.5 1.1 9.1 0.6 2.6 1 1 1 2 2 2 0 IBR domain zf-met PF12874.2 KFP05231.1 - 0.14 12.3 1.1 3.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-UBP PF02148.14 KFP05231.1 - 0.2 11.8 2.4 0.83 9.8 0.1 2.3 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein CCAP PF11105.3 KFP05231.1 - 0.24 11.1 0.7 0.24 11.1 0.5 1.2 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a CHORD PF04968.7 KFP05231.1 - 0.87 9.8 3.6 9.3 6.5 0.2 2.3 1 1 1 2 2 2 0 CHORD zf-C2HC_2 PF13913.1 KFP05231.1 - 9.2 6.0 10.5 5.6 6.7 0.1 3.4 4 1 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KFP05232.1 - 3.7e-08 33.2 12.6 0.00019 21.5 1.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP05232.1 - 1.3e-05 25.1 8.9 0.02 15.2 0.9 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP05232.1 - 0.0036 17.1 9.1 0.0088 15.9 0.3 2.5 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP05232.1 - 0.011 16.0 18.6 0.064 13.5 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Ogr_Delta PF04606.7 KFP05232.1 - 0.019 14.5 1.7 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 KFP05232.1 - 0.053 13.4 5.3 3.9 7.4 0.4 2.3 1 1 1 2 2 2 0 Zinc ribbon domain FYVE_2 PF02318.11 KFP05232.1 - 0.1 12.4 1.0 0.11 12.4 0.7 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger SAE2 PF08573.5 KFP05232.1 - 0.19 12.4 2.8 0.22 12.2 1.4 1.5 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF2688 PF10892.3 KFP05232.1 - 0.28 10.8 2.1 0.34 10.6 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) IBR PF01485.16 KFP05232.1 - 0.34 10.8 4.3 0.49 10.3 3.0 1.3 1 0 0 1 1 1 0 IBR domain zf-RING_2 PF13639.1 KFP05232.1 - 0.91 9.4 5.3 1.9 8.4 3.6 1.6 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KFP05232.1 - 1.3 9.0 5.3 1.4 9.0 2.6 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1059 PF06348.6 KFP05232.1 - 1.4 8.8 0.1 1.4 8.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1059) TFIIS_C PF01096.13 KFP05232.1 - 3.1 7.4 6.0 9.9 5.8 1.6 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_2 PF12756.2 KFP05232.1 - 3.5 7.7 9.3 2.3 8.3 0.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PH PF00169.24 KFP05233.1 - 4.5e-17 62.1 0.8 2e-16 60.0 0.6 2.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP05233.1 - 0.00021 21.5 4.5 0.00021 21.5 3.1 3.5 2 2 0 2 2 2 1 Pleckstrin homology domain EF-hand_6 PF13405.1 KFP05233.1 - 0.088 12.7 0.0 0.39 10.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Ribosomal_L2_C PF03947.13 KFP05233.1 - 0.14 12.0 0.1 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain zf-C4 PF00105.13 KFP05235.1 - 3.7e-09 36.6 5.0 5.8e-09 36.0 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FA_FANCE PF11510.3 KFP05236.1 - 1.4e-64 217.7 15.4 2.1e-64 217.2 10.7 1.2 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE MRVI1 PF05781.7 KFP05237.1 - 1.8e-51 175.1 3.1 2.4e-51 174.7 2.1 1.0 1 0 0 1 1 1 1 MRVI1 protein She9_MDM33 PF05546.6 KFP05237.1 - 0.0089 15.5 1.5 0.011 15.2 1.1 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Ribosomal_S10 PF00338.17 KFP05237.1 - 0.028 14.2 0.4 0.087 12.6 0.3 1.7 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e Not3 PF04065.10 KFP05237.1 - 0.053 12.7 3.4 0.066 12.4 2.3 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Exonuc_VII_L PF02601.10 KFP05237.1 - 0.064 12.4 2.2 0.078 12.1 1.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.1 KFP05237.1 - 0.11 12.4 14.3 0.19 11.7 5.3 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 KFP05237.1 - 0.17 10.7 8.5 0.25 10.2 5.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Gag_p17 PF00540.13 KFP05237.1 - 0.22 11.2 2.3 0.32 10.7 0.8 1.7 1 1 1 2 2 2 0 gag gene protein p17 (matrix protein) HR1 PF02185.11 KFP05237.1 - 0.26 11.0 11.2 2.4 7.9 1.5 3.2 3 0 0 3 3 3 0 Hr1 repeat APG6 PF04111.7 KFP05237.1 - 0.42 9.6 4.7 0.52 9.3 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 KFP05237.1 - 0.65 8.3 2.8 0.8 8.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FliJ PF02050.11 KFP05237.1 - 1.1 9.2 12.7 1.5 8.8 0.2 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Plasmid_RAQPRD PF09686.5 KFP05237.1 - 1.7 8.7 7.5 0.55 10.3 0.5 2.5 1 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) GrpE PF01025.14 KFP05237.1 - 2.4 7.6 7.9 7.8 6.0 3.0 2.2 1 1 1 2 2 2 0 GrpE YlqD PF11068.3 KFP05237.1 - 3.1 7.8 8.8 0.48 10.4 3.4 1.6 2 0 0 2 2 2 0 YlqD protein Exo_endo_phos PF03372.18 KFP05239.1 - 2.9e-18 66.6 0.0 4.1e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC2_membrane_4 PF12730.2 KFP05239.1 - 0.023 13.8 1.0 0.023 13.8 0.7 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein TEA PF01285.13 KFP05240.1 - 3.5e-186 619.5 0.0 4.3e-186 619.2 0.0 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Rotamase_2 PF13145.1 KFP05240.1 - 0.00077 20.0 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Myb_DNA-binding PF00249.26 KFP05240.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain CLAMP PF14769.1 KFP05240.1 - 0.11 12.6 2.0 4.3 7.5 0.7 2.3 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DUF1690 PF07956.6 KFP05240.1 - 0.11 12.4 2.3 0.27 11.2 0.9 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Tub PF01167.13 KFP05241.1 - 2.1e-116 387.1 0.0 2.4e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.3 KFP05241.1 - 0.13 11.7 0.1 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) FKBP_C PF00254.23 KFP05242.1 - 6.7e-45 151.0 0.0 1.6e-27 95.3 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 KFP05242.1 - 8.4e-18 63.7 3.1 2.8e-13 49.3 0.8 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFP05242.1 - 2e-16 58.8 8.3 9.1e-09 34.5 0.6 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFP05242.1 - 3.7e-11 42.0 6.3 3e-05 23.5 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP05242.1 - 7.3e-09 34.7 4.7 0.00042 19.8 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP05242.1 - 3.8e-07 29.9 0.6 0.00087 19.1 0.4 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP05242.1 - 1.2e-06 28.7 0.2 0.00012 22.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP05242.1 - 8.3e-06 25.2 0.2 4.1e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP05242.1 - 2.3e-05 24.1 0.2 8.7e-05 22.3 0.0 2.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFP05242.1 - 3.3e-05 23.6 1.4 0.0046 16.8 0.1 2.5 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KFP05242.1 - 0.00024 21.3 1.1 0.1 13.1 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFP05242.1 - 0.0006 20.4 0.1 0.0056 17.3 0.0 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP05242.1 - 0.0038 17.3 5.3 0.038 14.1 1.2 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFP05242.1 - 0.021 15.4 0.1 0.11 13.1 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFP05242.1 - 0.12 12.6 2.0 20 5.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Colipase_C PF02740.9 KFP05243.1 - 8.5e-24 83.0 3.2 1.4e-23 82.4 2.2 1.3 1 0 0 1 1 1 1 Colipase, C-terminal domain Colipase PF01114.13 KFP05243.1 - 1.8e-16 59.3 8.4 1.8e-16 59.3 5.9 1.6 2 0 0 2 2 2 1 Colipase, N-terminal domain Colipase-like PF15083.1 KFP05243.1 - 0.00012 21.9 6.7 0.00013 21.7 4.7 1.1 1 0 0 1 1 1 1 Colipase-like Metallothi_Euk2 PF12809.2 KFP05243.1 - 0.00054 20.2 12.8 0.00058 20.1 8.9 1.1 1 0 0 1 1 1 1 Eukaryotic metallothionein Prokineticin PF06607.6 KFP05243.1 - 1.8 8.7 8.3 4.1 7.5 5.7 1.6 1 1 0 1 1 1 0 Prokineticin L_HGMIC_fpl PF10242.4 KFP05244.1 - 3.3e-60 203.2 6.7 3.7e-60 203.0 4.7 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.15 KFP05244.1 - 0.00037 20.1 6.1 0.00055 19.6 4.2 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF4064 PF13273.1 KFP05244.1 - 0.2 11.7 3.4 8 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) YrhC PF14143.1 KFP05244.1 - 1.3 8.9 4.0 15 5.6 1.3 2.6 1 1 0 2 2 2 0 YrhC-like protein KdgT PF03812.8 KFP05244.1 - 2.9 6.9 8.4 0.94 8.5 3.3 1.9 2 1 0 2 2 2 0 2-keto-3-deoxygluconate permease Pkinase PF00069.20 KFP05245.1 - 3.2e-42 144.4 0.1 1.4e-23 83.3 0.1 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05245.1 - 2.2e-14 53.1 0.0 1.1e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFP05246.1 - 0.0065 15.6 0.0 0.0075 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KFP05247.1 - 3.6e-66 222.9 0.1 4.4e-66 222.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05247.1 - 7.8e-27 93.9 0.1 1.2e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP05247.1 - 3.9e-05 23.4 0.0 7.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFP05247.1 - 8.1e-05 21.7 0.1 0.00013 21.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP05247.1 - 0.00054 19.0 0.1 0.0016 17.4 0.0 1.8 2 1 0 2 2 2 1 Kinase-like DUF3754 PF12576.3 KFP05247.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) Epimerase_2 PF02350.14 KFP05247.1 - 0.11 11.1 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase zf-HC5HC2H_2 PF13832.1 KFP05248.1 - 9.1e-39 131.8 6.2 9.1e-39 131.8 4.3 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 KFP05248.1 - 2.1e-34 119.0 0.9 2.1e-34 119.0 0.6 3.1 3 0 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 KFP05248.1 - 1.1e-26 92.7 4.3 1.1e-26 92.7 3.0 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 KFP05248.1 - 4.1e-23 81.0 0.1 1.2e-22 79.6 0.1 1.8 1 0 0 1 1 1 1 Bromodomain PWWP PF00855.12 KFP05248.1 - 6.9e-14 51.8 0.0 2.4e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 PWWP domain PHD_2 PF13831.1 KFP05248.1 - 4e-12 45.2 6.6 4e-12 45.2 4.6 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KFP05248.1 - 2.8e-06 26.9 28.8 0.00049 19.7 11.8 2.8 2 0 0 2 2 2 2 PHD-finger DNA_topoisoIV PF00521.15 KFP05248.1 - 0.018 13.9 4.2 0.035 12.9 2.9 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A C1_1 PF00130.17 KFP05248.1 - 0.1 12.3 19.2 0.013 15.2 4.3 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RabGAP-TBC PF00566.13 KFP05249.1 - 4.1e-51 173.5 2.0 5.6e-51 173.0 1.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 KFP05250.1 - 7.9e-45 153.0 0.0 1.7e-44 151.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05250.1 - 2.8e-12 46.2 0.0 5.3e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP05250.1 - 4.4e-08 32.4 0.0 5.4e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP05250.1 - 7.9e-07 28.3 0.0 1.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP05250.1 - 0.0091 15.7 0.3 0.017 14.8 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP05250.1 - 0.062 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RecR PF02132.10 KFP05250.1 - 0.071 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 RecR protein Mito_carr PF00153.22 KFP05251.1 - 1.1e-15 57.1 0.2 3.1e-10 39.6 0.0 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein CAP PF00188.21 KFP05252.1 - 5.1e-22 78.6 0.4 7.1e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CDI PF02234.14 KFP05254.1 - 6.4e-21 73.8 3.3 7.1e-21 73.7 2.3 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor DUF2746 PF10874.3 KFP05254.1 - 0.13 12.4 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) RRM_1 PF00076.17 KFP05255.1 - 8.1e-18 63.8 0.0 1.2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05255.1 - 4e-11 42.7 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP05255.1 - 3.6e-10 39.5 0.0 4.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KFP05256.1 - 1.3e-57 194.9 0.3 1.3e-57 194.9 0.2 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05256.1 - 1.1e-28 100.0 2.5 1.3e-20 73.5 0.2 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KFP05256.1 - 6.3e-07 29.8 0.9 1.4e-06 28.7 0.6 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFP05256.1 - 3e-06 26.4 0.4 3.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP05256.1 - 0.003 16.6 0.7 0.0051 15.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP05256.1 - 0.0031 17.2 0.1 0.028 14.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Alpha-2-MRAP_N PF06400.6 KFP05256.1 - 0.026 14.1 1.5 0.055 13.1 1.1 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, N-terminal domain Seadorna_VP7 PF07387.6 KFP05256.1 - 0.078 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BTB_2 PF02214.17 KFP05257.1 - 4.6e-06 26.7 0.0 9.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.26 KFP05258.1 - 1.1e-33 116.2 8.7 1.4e-33 115.8 4.5 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP05258.1 - 1.5e-28 98.8 0.1 2.6e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP05258.1 - 1.8e-13 49.9 6.0 1.8e-13 49.9 4.2 2.5 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFP05258.1 - 8.1e-05 21.2 0.6 0.00014 20.3 0.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KFP05259.1 - 7.3e-35 120.0 5.7 1.1e-34 119.4 2.5 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP05259.1 - 2.2e-19 69.4 0.1 4e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP05259.1 - 1.7e-13 50.0 6.0 1.7e-13 50.0 4.2 2.5 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFP05259.1 - 8.3e-05 21.1 0.9 0.00017 20.1 0.7 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KFP05260.1 - 4.4e-35 120.7 5.1 4.4e-35 120.7 3.6 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP05260.1 - 7.1e-29 99.8 0.1 1.2e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP05260.1 - 3.1e-14 52.4 4.8 3.1e-14 52.4 3.3 2.5 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 KFP05260.1 - 0.001 17.5 0.9 0.001 17.5 0.6 1.5 2 0 0 2 2 2 1 Polycystin cation channel DUF202 PF02656.10 KFP05260.1 - 5.5 7.2 5.4 1.1e+02 3.1 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Ion_trans PF00520.26 KFP05261.1 - 2.5e-33 115.0 9.9 5.6e-33 113.8 5.6 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP05261.1 - 8e-24 83.6 0.1 1.7e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP05261.1 - 4.8e-13 48.6 6.0 4.8e-13 48.6 4.1 2.9 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.7 KFP05261.1 - 4.2e-05 22.1 0.2 4.2e-05 22.1 0.1 2.1 1 1 0 2 2 2 1 Polycystin cation channel DUF423 PF04241.10 KFP05261.1 - 0.11 12.4 0.4 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF202 PF02656.10 KFP05261.1 - 0.26 11.5 3.4 34 4.7 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) I-set PF07679.11 KFP05262.1 - 1.5e-72 239.5 0.0 2e-13 49.9 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05262.1 - 1.4e-51 172.5 0.0 8.7e-11 41.8 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFP05262.1 - 1.2e-42 144.2 0.0 1.4e-06 28.6 0.0 7.0 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 KFP05262.1 - 1.4e-42 143.7 15.5 4.1e-12 46.0 0.0 5.6 5 0 0 5 5 5 5 Fibronectin type III domain ig PF00047.20 KFP05262.1 - 2.1e-31 107.8 0.0 4.6e-08 33.0 0.0 7.3 7 0 0 7 7 7 5 Immunoglobulin domain Bravo_FIGEY PF13882.1 KFP05262.1 - 7.1e-26 90.9 8.1 1.8e-25 89.6 5.6 1.7 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.12 KFP05262.1 - 1e-14 54.3 2.4 0.0019 18.0 0.0 7.3 5 5 1 6 6 6 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP05262.1 - 2e-11 43.6 0.6 0.067 13.1 0.0 6.6 6 1 1 7 7 7 2 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP05262.1 - 2.5e-05 22.7 0.0 1 7.5 0.0 4.0 3 1 1 4 4 4 2 Alphaherpesvirus glycoprotein E BiPBP_C PF06832.7 KFP05262.1 - 3e-05 23.8 0.1 0.075 12.9 0.0 4.0 5 0 0 5 5 4 1 Penicillin-Binding Protein C-terminus Family V-set_CD47 PF08204.6 KFP05262.1 - 0.004 16.9 0.3 10 5.9 0.0 3.9 4 0 0 4 4 4 1 CD47 immunoglobulin-like domain I-set PF07679.11 KFP05263.1 - 4.3e-68 225.2 0.0 6.7e-16 57.9 0.0 6.8 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05263.1 - 3.6e-56 187.2 0.1 1.8e-10 40.7 0.0 6.7 5 1 1 6 6 6 6 Immunoglobulin domain Ig_3 PF13927.1 KFP05263.1 - 1.9e-49 165.9 0.1 1.5e-08 35.0 0.0 7.8 7 1 1 8 8 8 6 Immunoglobulin domain fn3 PF00041.16 KFP05263.1 - 8.2e-45 150.8 4.7 2.1e-16 59.7 0.0 4.5 4 0 0 4 4 4 4 Fibronectin type III domain ig PF00047.20 KFP05263.1 - 5.7e-34 116.0 2.3 2.6e-05 24.2 0.0 8.3 8 1 0 8 8 8 5 Immunoglobulin domain V-set PF07686.12 KFP05263.1 - 4.7e-29 100.5 2.4 2e-05 24.4 0.0 8.4 5 2 1 6 6 6 6 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP05263.1 - 3.5e-07 30.0 1.4 0.055 13.3 0.0 4.9 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFP05263.1 - 1.6e-05 24.7 0.0 0.99 9.3 0.0 3.6 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Sp38 PF07354.7 KFP05263.1 - 0.00012 20.8 0.1 0.013 14.1 0.0 3.0 2 1 0 3 3 3 1 Zona-pellucida-binding protein (Sp38) C2-set PF05790.10 KFP05263.1 - 0.00019 21.3 0.1 7.9 6.5 0.0 5.4 5 1 1 6 6 6 1 Immunoglobulin C2-set domain Interfer-bind PF09294.5 KFP05263.1 - 0.0021 18.0 0.0 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III ig PF00047.20 KFP05264.1 - 0.0053 16.8 0.1 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFP05264.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain TSP_1 PF00090.14 KFP05264.1 - 2.9 8.0 7.5 0.9 9.7 2.2 2.2 2 0 0 2 2 2 0 Thrombospondin type 1 domain WD40 PF00400.27 KFP05265.1 - 3.2e-15 55.3 23.9 1.6e-07 30.9 1.6 6.7 7 1 0 7 7 7 5 WD domain, G-beta repeat DUF3312 PF11768.3 KFP05265.1 - 0.2 9.8 0.1 0.31 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Pkinase PF00069.20 KFP05266.1 - 3.3e-43 147.7 0.0 1.1e-42 145.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05266.1 - 4.1e-36 124.3 0.0 7.5e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP05266.1 - 8e-05 21.7 0.4 0.00023 20.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP05266.1 - 0.0021 17.1 0.4 0.0054 15.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP05266.1 - 0.0058 16.3 0.2 0.28 10.8 0.0 3.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family SSPI PF14098.1 KFP05266.1 - 0.075 12.9 0.9 0.34 10.8 0.6 2.2 1 0 0 1 1 1 0 Small, acid-soluble spore protein I Tmemb_cc2 PF10267.4 KFP05267.1 - 5.8e-191 634.2 8.1 9.5e-191 633.5 5.6 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein ABC2_membrane_3 PF12698.2 KFP05267.1 - 0.0091 15.0 0.6 0.029 13.4 0.1 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF1479 PF07350.7 KFP05267.1 - 0.014 13.9 4.3 0.035 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) DUF2313 PF10076.4 KFP05267.1 - 0.014 14.7 1.1 0.024 14.0 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) Baculo_PEP_C PF04513.7 KFP05267.1 - 0.031 14.1 0.8 0.031 14.1 0.6 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 KFP05267.1 - 0.045 11.2 15.0 0.0026 15.3 4.2 2.3 2 0 0 2 2 2 0 Prominin Lipoprotein_20 PF13942.1 KFP05267.1 - 0.31 10.5 16.3 0.77 9.2 1.0 2.5 2 1 0 2 2 2 0 YfhG lipoprotein DUF2207 PF09972.4 KFP05267.1 - 3 6.3 6.8 0.53 8.8 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3584 PF12128.3 KFP05267.1 - 4.5 4.4 28.9 0.65 7.2 9.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3417 PF11897.3 KFP05267.1 - 7 6.6 11.4 14 5.6 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) OmpH PF03938.9 KFP05267.1 - 8.2 6.3 28.1 0.58 10.0 8.1 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Kelch_1 PF01344.20 KFP05268.1 - 1.3e-47 159.0 0.0 9e-09 34.7 0.0 7.1 7 0 0 7 7 7 7 Kelch motif Kelch_6 PF13964.1 KFP05268.1 - 2.9e-41 137.9 0.3 2.3e-08 33.8 0.0 7.1 3 3 4 7 7 7 7 Kelch motif Kelch_4 PF13418.1 KFP05268.1 - 2e-26 91.4 0.5 1.5e-06 27.8 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KFP05268.1 - 3.6e-22 77.9 0.1 9.4e-06 25.6 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP05268.1 - 1.2e-19 69.1 0.0 3.3e-05 23.4 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KFP05268.1 - 6.1e-10 38.8 0.6 0.019 14.9 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Ribosomal_L34e PF01199.13 KFP05269.1 - 9.2e-38 128.3 8.1 1.1e-37 128.0 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e OST3_OST6 PF04756.8 KFP05270.1 - 1.4e-30 105.9 0.2 2.1e-30 105.3 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family DUF998 PF06197.8 KFP05270.1 - 0.74 9.1 5.0 6.6 6.0 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF998) Aminotran_3 PF00202.16 KFP05271.1 - 1.7e-76 257.2 0.0 2.1e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF3301 PF11743.3 KFP05271.1 - 0.033 13.6 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Sec23_trunk PF04811.10 KFP05272.1 - 5.1e-79 265.0 0.0 1.2e-78 263.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFP05272.1 - 8.7e-27 92.5 3.5 2.9e-26 90.8 2.4 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFP05272.1 - 2.9e-21 75.8 0.0 7.6e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFP05272.1 - 7.1e-16 57.4 5.1 1.4e-15 56.5 3.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFP05272.1 - 5.5e-11 42.0 0.0 1.3e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Sen15 PF09631.5 KFP05272.1 - 0.052 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Sen15 protein DUF607 PF04678.8 KFP05273.1 - 2.3e-58 197.0 1.4 2.9e-58 196.7 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF607 NDUF_C2 PF06374.6 KFP05273.1 - 0.0019 18.1 2.2 0.0032 17.4 0.3 2.0 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Wbp11 PF09429.5 KFP05273.1 - 4.7 7.2 7.4 4.5 7.3 0.5 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 Peptidase_C14 PF00656.17 KFP05274.1 - 1.2e-50 172.5 0.1 1.4e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain PLA2G12 PF06951.6 KFP05275.1 - 8.7e-64 214.6 10.4 9.5e-64 214.4 7.2 1.0 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_2 PF05826.7 KFP05275.1 - 0.28 11.1 12.3 1.5 8.7 1.5 2.4 1 1 1 2 2 2 0 Phospholipase A2 Trypsin PF00089.21 KFP05276.1 - 2.5e-34 118.8 0.0 2.5e-34 118.8 0.0 1.6 2 0 0 2 2 2 1 Trypsin Ldl_recept_a PF00057.13 KFP05276.1 - 8.9e-14 51.1 28.9 7.3e-09 35.3 8.8 4.1 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SRCR PF00530.13 KFP05276.1 - 3.8e-09 36.7 3.7 3.8e-09 36.7 2.6 3.4 2 1 2 4 4 4 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFP05276.1 - 4.9e-06 26.6 3.1 5.2e-06 26.6 0.9 2.1 1 1 1 2 2 2 1 Scavenger receptor cysteine-rich domain Gar1 PF04410.9 KFP05277.1 - 3e-38 130.7 0.1 3.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region 7tm_1 PF00001.16 KFP05278.1 - 1.5e-46 158.6 15.1 1.8e-46 158.3 10.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05278.1 - 1.9e-11 43.6 12.2 2.2e-11 43.3 8.5 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Ldl_recept_b PF00058.12 KFP05279.1 - 2.2e-43 146.2 0.7 3.4e-09 36.8 0.0 7.8 8 0 0 8 8 8 6 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFP05279.1 - 5.2e-36 122.4 147.0 4.3e-08 33.1 4.7 11.4 11 0 0 11 11 11 8 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP05279.1 - 6.9e-32 108.7 77.0 2.2e-05 23.9 3.2 11.6 11 0 0 11 11 11 9 Complement Clr-like EGF-like EGF_CA PF07645.10 KFP05279.1 - 8.8e-22 76.8 51.4 1.3e-07 31.4 7.0 11.3 11 0 0 11 11 11 5 Calcium-binding EGF domain EGF PF00008.22 KFP05279.1 - 3.1e-19 68.5 111.8 1.9e-05 24.4 3.0 11.0 10 0 0 10 10 10 8 EGF-like domain EGF_3 PF12947.2 KFP05279.1 - 1.5e-16 60.0 116.6 5.4e-06 26.2 8.4 10.8 10 0 0 10 10 10 7 EGF domain SGL PF08450.7 KFP05279.1 - 8.2e-07 28.6 0.2 0.33 10.2 0.0 4.4 2 1 2 4 4 4 2 SMP-30/Gluconolaconase/LRE-like region MMtag PF10159.4 KFP05279.1 - 0.082 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Kinase phosphorylation protein ELO PF01151.13 KFP05280.1 - 3.3e-65 219.8 25.1 3.7e-65 219.6 17.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Homeobox PF00046.24 KFP05281.1 - 8.1e-23 79.8 9.2 1.4e-22 79.0 6.4 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFP05281.1 - 6.3e-10 38.2 0.9 6.3e-10 38.2 0.6 2.0 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.6 KFP05281.1 - 0.0026 17.4 0.7 0.0099 15.5 0.5 2.0 1 0 0 1 1 1 1 Homeobox KN domain HTH_32 PF13565.1 KFP05281.1 - 0.55 11.0 4.3 0.16 12.7 0.6 1.8 1 1 1 2 2 2 0 Homeodomain-like domain DUF4605 PF15378.1 KFP05282.1 - 2.4e-28 97.5 7.4 3.7e-28 97.0 4.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4605) PHO4 PF01384.15 KFP05283.1 - 3.9e-128 426.6 0.0 7.1e-128 425.8 0.0 1.4 1 1 0 1 1 1 1 Phosphate transporter family Vpu PF00558.14 KFP05283.1 - 0.019 14.4 0.2 0.019 14.4 0.1 2.1 2 0 0 2 2 2 0 Vpu protein Syndecan PF01034.15 KFP05283.1 - 0.17 11.5 4.5 0.8 9.4 0.1 3.7 3 0 0 3 3 3 0 Syndecan domain Pkinase_Tyr PF07714.12 KFP05284.1 - 4.3e-09 35.8 0.1 5.7e-08 32.1 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KFP05284.1 - 1.8e-07 30.6 0.0 1.8e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain PIP49_C PF12260.3 KFP05284.1 - 0.00047 19.6 0.1 0.00073 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 TPR_19 PF14559.1 KFP05285.1 - 0.0088 16.3 0.1 0.04 14.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFP05285.1 - 0.019 14.5 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Apc3 PF12895.2 KFP05285.1 - 0.053 13.6 0.6 0.24 11.5 0.1 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KFP05285.1 - 0.14 12.8 0.1 4.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CHGN PF05679.11 KFP05286.1 - 1.5e-56 192.1 0.1 2.2e-56 191.6 0.0 1.3 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_tranf_2_2 PF10111.4 KFP05286.1 - 8.1e-11 41.5 0.1 1.6e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFP05286.1 - 2.7e-10 39.5 0.9 6e-10 38.4 0.6 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.21 KFP05286.1 - 0.0021 17.7 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 LUC7 PF03194.10 KFP05286.1 - 0.018 14.5 0.7 0.031 13.8 0.5 1.3 1 0 0 1 1 1 0 LUC7 N_terminus THOC7 PF05615.8 KFP05286.1 - 0.078 13.2 0.4 0.078 13.2 0.3 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 SH2 PF00017.19 KFP05287.1 - 7.7e-14 51.2 0.0 1.7e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 SH2 domain TetM_leader PF08076.6 KFP05287.1 - 0.11 12.0 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Sulfotransfer_1 PF00685.22 KFP05288.1 - 3.6e-86 288.7 0.0 4.1e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP05288.1 - 0.0018 19.2 0.1 0.0043 18.0 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 KFP05288.1 - 0.019 14.4 0.1 5.9 6.3 0.0 2.7 2 1 0 2 2 2 0 Stf0 sulphotransferase UDPGT PF00201.13 KFP05289.1 - 2.5e-220 732.2 0.0 2.8e-220 732.0 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 KFP05289.1 - 1.5e-06 27.6 0.0 0.00012 21.3 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 KFP05289.1 - 4.2e-06 26.5 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Citrate_synt PF00285.16 KFP05289.1 - 0.093 11.4 0.0 5.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Citrate synthase Leo1 PF04004.8 KFP05289.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Leo1-like protein Prominin PF05478.6 KFP05289.1 - 2 5.8 6.0 2.9 5.3 4.2 1.2 1 0 0 1 1 1 0 Prominin YTH PF04146.10 KFP05290.1 - 5.3e-42 142.7 0.0 8.1e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Pkinase_Tyr PF07714.12 KFP05291.1 - 3.1e-98 327.9 0.0 3.6e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP05291.1 - 3.1e-50 170.7 0.0 3.7e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFP05291.1 - 1.4e-16 60.6 0.3 2.3e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.9 KFP05291.1 - 0.027 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.7 KFP05292.1 - 1.8e-27 95.2 0.5 4.1e-27 94.1 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFP05292.1 - 7e-26 90.3 0.1 1.4e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFP05292.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFP05292.1 - 0.11 11.9 0.3 0.21 10.9 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KFP05292.1 - 0.16 11.8 1.3 0.39 10.5 0.5 1.9 2 0 0 2 2 2 0 ThiF family ADH_N PF08240.7 KFP05293.1 - 7e-28 96.5 0.4 2.3e-27 94.8 0.3 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFP05293.1 - 2e-21 75.8 0.5 3.6e-21 75.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFP05293.1 - 0.0026 18.6 0.0 0.0055 17.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFP05293.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M24 PF00557.19 KFP05294.1 - 4e-49 167.0 0.3 4.9e-49 166.7 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 IF4E PF01652.13 KFP05295.1 - 3.7e-58 195.6 0.1 4.4e-58 195.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tetraspannin PF00335.15 KFP05296.1 - 4e-49 166.8 17.5 5.2e-49 166.5 12.1 1.1 1 0 0 1 1 1 1 Tetraspanin family zf-DHHC PF01529.15 KFP05296.1 - 0.14 11.5 1.5 0.48 9.7 0.0 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Arm PF00514.18 KFP05297.1 - 3.5e-30 102.7 19.6 9.9e-08 31.5 0.1 8.2 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP05297.1 - 7.9e-08 32.4 9.8 0.067 13.4 0.0 5.4 3 2 2 5 5 5 4 HEAT repeats V-ATPase_H_N PF03224.9 KFP05297.1 - 0.00016 20.8 8.1 0.048 12.7 1.2 4.5 1 1 1 2 2 2 2 V-ATPase subunit H HEAT_EZ PF13513.1 KFP05297.1 - 0.0025 18.2 8.9 4.5 7.9 0.1 5.1 6 0 0 6 6 6 2 HEAT-like repeat Nitr_red_bet_C PF14711.1 KFP05297.1 - 0.044 13.2 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal HEAT PF02985.17 KFP05297.1 - 0.99 9.6 3.8 82 3.6 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat Yae1_N PF09811.4 KFP05298.1 - 3e-14 52.2 41.0 3.2e+03 -2.3 28.4 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal ZU5 PF00791.15 KFP05299.1 - 3.5e-38 129.3 0.1 6.8e-38 128.4 0.1 1.5 1 0 0 1 1 1 1 ZU5 domain I-set PF07679.11 KFP05299.1 - 2.6e-12 46.4 1.8 5.2e-11 42.2 0.1 3.1 3 0 0 3 3 3 1 Immunoglobulin I-set domain Death PF00531.17 KFP05299.1 - 3.4e-12 45.9 0.1 6.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Death domain TSP_1 PF00090.14 KFP05299.1 - 4.5e-10 39.4 29.4 7e-08 32.4 5.8 2.7 2 0 0 2 2 2 2 Thrombospondin type 1 domain Ig_2 PF13895.1 KFP05299.1 - 1.4e-08 34.7 3.6 6.6e-07 29.3 0.0 4.1 3 2 0 4 4 4 1 Immunoglobulin domain Ig_3 PF13927.1 KFP05299.1 - 5.3e-05 23.6 0.2 0.00093 19.6 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain V-set PF07686.12 KFP05299.1 - 0.00085 19.1 0.0 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin V-set domain Pkinase PF00069.20 KFP05300.1 - 3.2e-54 183.8 0.0 4.3e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05300.1 - 2.2e-38 131.8 0.0 2.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFP05300.1 - 1.2e-15 56.4 0.3 2.9e-15 55.2 0.2 1.7 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFP05300.1 - 1.2e-10 41.8 1.4 2e-10 41.1 0.4 1.9 2 0 0 2 2 2 1 Activin types I and II receptor domain Adeno_E3_CR2 PF02439.10 KFP05300.1 - 0.016 14.7 0.6 0.029 13.9 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4448 PF14610.1 KFP05300.1 - 0.045 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) APH PF01636.18 KFP05300.1 - 0.18 11.5 0.0 0.38 10.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family 7tm_1 PF00001.16 KFP05301.1 - 2.3e-60 203.8 20.5 2.9e-60 203.5 14.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05301.1 - 6e-17 61.6 16.4 7.6e-17 61.3 11.3 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP05301.1 - 1.7e-09 37.2 7.5 2.9e-09 36.4 5.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFP05301.1 - 5.9e-09 35.4 19.0 1.1e-08 34.5 13.2 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.3 KFP05301.1 - 0.0033 17.0 11.7 0.0033 17.0 8.1 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 CcmH PF03918.9 KFP05301.1 - 0.047 12.6 0.0 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein PepSY_TM_2 PF13703.1 KFP05301.1 - 0.78 9.9 8.8 0.27 11.4 2.0 2.7 2 0 0 2 2 2 0 PepSY-associated TM helix Phage_Treg PF04761.7 KFP05302.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator GST_N PF02798.15 KFP05303.1 - 2.7e-20 72.3 0.0 6.8e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFP05303.1 - 2.5e-07 30.6 0.1 3.9e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFP05303.1 - 3.8e-06 27.0 0.0 8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFP05303.1 - 5.6e-06 26.7 0.3 1.1e-05 25.7 0.2 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFP05303.1 - 0.00054 19.7 1.2 0.0017 18.2 0.8 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFP05303.1 - 0.0026 17.7 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SNF2_N PF00176.18 KFP05304.1 - 8.9e-70 234.8 1.7 1.4e-69 234.1 1.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFP05304.1 - 1.2e-13 50.7 0.0 3.3e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP05304.1 - 2.5e-07 30.7 0.5 2.6e-06 27.4 0.0 3.0 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit CUE PF02845.11 KFP05304.1 - 1.4e-06 27.6 0.5 0.033 13.6 0.0 2.6 2 0 0 2 2 2 2 CUE domain DEAD PF00270.24 KFP05304.1 - 5.5e-06 25.9 0.0 1.5e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 KFP05304.1 - 0.024 14.5 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif MFMR PF07777.6 KFP05304.1 - 0.56 10.1 7.8 1.3 8.8 5.4 1.6 1 0 0 1 1 1 0 G-box binding protein MFMR Mito_carr PF00153.22 KFP05305.1 - 1.8e-55 184.6 4.9 2.9e-21 74.9 0.4 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein LRR_8 PF13855.1 KFP05306.1 - 7.3e-77 253.0 68.9 7.6e-16 57.6 2.5 7.9 2 1 7 9 9 9 9 Leucine rich repeat I-set PF07679.11 KFP05306.1 - 3.4e-54 180.6 0.0 1.2e-21 76.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain LRR_4 PF12799.2 KFP05306.1 - 1.2e-41 139.7 47.2 5.2e-06 25.9 1.3 9.6 3 1 5 10 10 10 10 Leucine Rich repeats (2 copies) Ig_2 PF13895.1 KFP05306.1 - 5.1e-37 125.8 0.1 5.3e-12 45.6 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP05306.1 - 1.2e-27 96.1 0.0 1.1e-09 38.6 0.1 4.4 3 2 0 3 3 3 3 Immunoglobulin domain LRR_1 PF00560.28 KFP05306.1 - 6.3e-27 89.4 38.6 0.26 11.4 0.0 15.8 16 0 0 16 16 15 10 Leucine Rich Repeat LRR_5 PF13306.1 KFP05306.1 - 1e-26 93.1 0.0 3.6e-09 36.3 0.0 4.1 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) ig PF00047.20 KFP05306.1 - 6e-20 71.1 0.0 2.8e-08 33.7 0.0 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP05306.1 - 1.7e-18 66.6 0.1 0.00016 21.5 0.0 4.0 3 2 0 3 3 3 3 Immunoglobulin V-set domain LRR_6 PF13516.1 KFP05306.1 - 3.1e-12 45.2 42.4 1.9 8.8 0.0 14.6 15 1 1 16 16 15 3 Leucine Rich repeat C2-set_2 PF08205.7 KFP05306.1 - 3.5e-10 39.6 0.1 0.0022 17.8 0.0 3.6 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain LRR_7 PF13504.1 KFP05306.1 - 4.8e-09 34.9 48.2 3.8 8.1 0.2 15.6 16 0 0 16 16 16 2 Leucine rich repeat LRR_9 PF14580.1 KFP05306.1 - 8.8e-08 31.8 7.3 0.083 12.4 0.1 4.8 1 1 4 5 5 5 2 Leucine-rich repeat LRRCT PF01463.19 KFP05306.1 - 0.0063 16.6 0.0 0.026 14.7 0.0 2.2 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain BACK PF07707.10 KFP05307.1 - 2.9e-31 107.3 1.9 2.1e-30 104.5 0.5 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFP05307.1 - 1e-28 98.6 15.3 3.9e-10 39.0 0.3 5.8 6 0 0 6 6 6 4 Kelch motif BTB PF00651.26 KFP05307.1 - 1.9e-28 98.6 0.3 3.6e-28 97.7 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 KFP05307.1 - 1.4e-26 91.5 3.0 4.3e-06 26.6 0.0 5.8 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFP05307.1 - 2e-12 46.6 0.9 0.011 15.4 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP05307.1 - 3.2e-12 45.6 6.7 3.9e-06 26.4 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 KFP05307.1 - 5.5e-10 39.1 0.7 0.0063 16.6 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF3342 PF11822.3 KFP05307.1 - 0.0015 17.7 0.1 0.005 16.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3342) Kelch_5 PF13854.1 KFP05307.1 - 0.0017 18.2 2.3 22 5.1 0.0 4.4 4 0 0 4 4 4 0 Kelch motif PSII_BNR PF14870.1 KFP05307.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.6 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 MFS_1 PF07690.11 KFP05308.1 - 3.8e-45 154.1 22.6 1.7e-38 132.2 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFP05308.1 - 3.9e-07 29.7 11.9 0.053 13.3 0.0 5.3 5 1 1 6 6 6 3 MFS_1 like family DUF2371 PF10177.4 KFP05308.1 - 0.74 9.6 2.6 4.6 7.1 0.0 3.1 3 1 1 4 4 4 0 Uncharacterised conserved protein (DUF2371) ATP-grasp_2 PF08442.5 KFP05309.1 - 1.6e-76 256.2 0.7 2.5e-76 255.5 0.5 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KFP05309.1 - 4.9e-27 94.4 0.2 1.1e-26 93.3 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KFP05309.1 - 1.3e-09 37.6 0.3 2.6e-09 36.6 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KFP05309.1 - 0.0011 18.5 0.1 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KFP05309.1 - 0.038 13.7 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DUF552 PF04472.7 KFP05309.1 - 0.055 13.3 0.1 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF552) ATP-grasp PF02222.17 KFP05309.1 - 0.087 12.1 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain TAFA PF12020.3 KFP05310.1 - 4.9e-55 183.6 12.0 5.4e-55 183.4 8.3 1.0 1 0 0 1 1 1 1 TAFA family TAFA PF12020.3 KFP05311.1 - 1.2e-25 89.4 2.0 2.3e-25 88.5 1.4 1.5 1 0 0 1 1 1 1 TAFA family DUF718 PF05336.8 KFP05311.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF718) DUF563 PF04577.9 KFP05312.1 - 7.1e-25 88.1 0.3 1.1e-24 87.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TMF_TATA_bd PF12325.3 KFP05313.1 - 5.7e-37 126.1 10.4 5.7e-37 126.1 7.2 7.7 2 1 4 7 7 7 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KFP05313.1 - 3.5e-18 65.1 25.0 3.5e-18 65.1 17.4 11.2 5 4 6 11 11 11 5 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 KFP05313.1 - 0.006 16.9 3.7 0.006 16.9 2.5 9.6 5 3 8 13 13 13 3 SlyX E2_bind PF08825.5 KFP05314.1 - 2.9e-26 91.0 0.4 6.4e-26 89.9 0.3 1.6 1 0 0 1 1 1 1 E2 binding domain ThiF PF00899.16 KFP05314.1 - 1.1e-25 90.0 0.0 3.9e-24 85.0 0.0 3.0 2 1 0 2 2 2 1 ThiF family UBACT PF02134.16 KFP05314.1 - 3.5e-23 80.9 0.2 6.8e-23 80.0 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KFP05314.1 - 4.5e-12 45.1 0.8 1e-11 44.0 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KFP05314.1 - 4.2e-05 23.0 0.0 9.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 KFP05314.1 - 0.00043 20.4 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 KFP05314.1 - 0.0058 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.22 KFP05314.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.3 KFP05314.1 - 0.16 11.8 0.7 0.35 10.7 0.5 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein PRA1 PF03208.14 KFP05315.1 - 1.2e-18 66.9 1.4 1.4e-18 66.7 0.9 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF1049 PF06305.6 KFP05315.1 - 0.018 14.5 4.0 1.8 8.1 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4446 PF14584.1 KFP05315.1 - 0.029 14.1 1.7 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF2781 PF10914.3 KFP05315.1 - 0.032 13.9 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF3981 PF13139.1 KFP05315.1 - 0.07 13.1 1.6 0.14 12.1 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) Spin-Ssty PF02513.12 KFP05315.1 - 0.095 12.2 0.5 0.23 11.0 0.3 1.6 1 0 0 1 1 1 0 Spin/Ssty Family Melibiase PF02065.13 KFP05315.1 - 0.1 11.2 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Melibiase DUF192 PF02643.10 KFP05315.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized ACR, COG1430 DUF3487 PF11990.3 KFP05315.1 - 0.22 10.9 4.5 0.48 9.8 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) Baculo_11_kDa PF06143.6 KFP05315.1 - 3.8 6.9 5.7 12 5.3 0.8 2.3 1 1 1 2 2 2 0 Baculovirus 11 kDa family DUF3338 PF11819.3 KFP05316.1 - 5.4e-59 197.5 7.6 5.4e-59 197.5 5.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) FERM_C PF09380.5 KFP05316.1 - 3.1e-19 68.9 0.5 1e-18 67.2 0.4 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFP05316.1 - 1.5e-16 60.6 0.1 1.5e-16 60.6 0.0 3.1 3 0 0 3 3 3 1 FERM central domain FERM_N PF09379.5 KFP05316.1 - 2.2e-15 56.4 0.0 6e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain DHQ_synthase PF01761.15 KFP05317.1 - 3.7e-57 193.2 0.0 4.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 KFP05317.1 - 2.6e-15 56.4 0.0 5.7e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 KFP05317.1 - 1.6e-05 23.7 0.0 2.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase MDFI PF15316.1 KFP05318.1 - 3.9e-16 59.5 14.1 4.6e-16 59.3 9.8 1.1 1 0 0 1 1 1 1 MyoD family inhibitor Fork_head PF00250.13 KFP05319.1 - 5.4e-26 90.4 0.1 1.6e-25 88.9 0.1 1.8 1 0 0 1 1 1 1 Fork head domain Ribosomal_L27e PF01777.13 KFP05319.1 - 7.4 6.7 8.8 5.7 7.1 0.2 3.2 3 1 0 3 3 3 0 Ribosomal L27e protein family Yae1_N PF09811.4 KFP05320.1 - 9.9e-23 79.3 79.2 1.5e+04 -33.3 54.9 6.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal IF4E PF01652.13 KFP05321.1 - 2.1e-39 134.7 0.0 2.4e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E 7tm_1 PF00001.16 KFP05322.1 - 1.4e-33 116.0 11.4 2e-33 115.6 7.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Prokineticin PF06607.6 KFP05323.1 - 9.3e-40 134.6 9.4 1e-39 134.5 6.5 1.0 1 0 0 1 1 1 1 Prokineticin zf-RanBP PF00641.13 KFP05324.1 - 1.5e-08 33.5 2.4 3e-08 32.6 1.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MIP-T3 PF10243.4 KFP05324.1 - 2.3 6.5 29.1 2.9 6.2 20.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SHQ1 PF04925.10 KFP05325.1 - 2.2e-67 226.1 0.6 3.8e-67 225.4 0.4 1.3 1 0 0 1 1 1 1 SHQ1 protein Glyco_transf_8 PF01501.15 KFP05326.1 - 2.5e-15 56.5 0.1 5.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF3539 PF12058.3 KFP05326.1 - 0.071 12.9 0.1 0.51 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3539) PPP4R2 PF09184.6 KFP05327.1 - 1.6e-90 303.6 0.3 1.6e-90 303.6 0.2 2.8 1 1 2 3 3 3 1 PPP4R2 CDC27 PF09507.5 KFP05327.1 - 5.9 6.0 44.8 7.8 5.6 31.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PDZ PF00595.19 KFP05328.1 - 9.2e-20 70.6 1.3 1.6e-14 53.8 0.1 2.5 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP05328.1 - 3.8e-07 29.8 0.3 3.6e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.1 KFP05328.1 - 0.0033 17.1 0.0 0.0098 15.6 0.0 1.8 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ PF00595.19 KFP05329.1 - 4.4e-08 33.1 0.3 7.5e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) zf-C3HC4 PF00097.20 KFP05329.1 - 6.7e-08 32.0 6.2 1.7e-07 30.7 4.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP05329.1 - 7.1e-08 32.1 8.0 1.9e-07 30.7 5.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP05329.1 - 1e-07 31.8 8.0 2.5e-07 30.6 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP05329.1 - 3.8e-07 29.7 6.6 1e-06 28.3 4.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP05329.1 - 3.7e-06 26.4 5.3 8.3e-06 25.3 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP05329.1 - 1.7e-05 24.5 7.8 3.7e-05 23.5 5.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Sina PF03145.11 KFP05329.1 - 0.00078 19.1 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-RING_6 PF14835.1 KFP05329.1 - 0.0016 18.1 2.5 0.0043 16.7 1.7 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 KFP05329.1 - 0.0049 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.2 KFP05329.1 - 0.015 15.4 2.8 0.046 13.8 1.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFP05329.1 - 0.092 12.4 6.1 0.28 10.9 4.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger PDZ_2 PF13180.1 KFP05329.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Prok-RING_4 PF14447.1 KFP05329.1 - 0.17 11.4 5.9 0.6 9.7 4.1 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Syntaxin_2 PF14523.1 KFP05330.1 - 4.9e-22 77.8 8.2 4.9e-22 77.8 5.7 2.1 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KFP05330.1 - 3.1e-08 33.1 8.5 4.1e-08 32.7 3.0 3.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFP05330.1 - 1.7e-06 28.1 4.4 1.7e-06 28.1 3.0 2.4 3 0 0 3 3 2 1 Syntaxin DUF1664 PF07889.7 KFP05330.1 - 0.026 14.2 10.1 2.4 7.9 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Talin_middle PF09141.5 KFP05330.1 - 0.028 14.1 2.7 3.2 7.3 0.1 2.5 2 1 0 2 2 2 0 Talin, middle domain AAA_13 PF13166.1 KFP05330.1 - 0.1 11.0 7.7 0.15 10.4 5.3 1.2 1 0 0 1 1 1 0 AAA domain NYD-SP28 PF14772.1 KFP05330.1 - 0.11 12.6 0.2 0.11 12.6 0.1 2.7 2 1 0 2 2 2 0 Sperm tail MCPsignal PF00015.16 KFP05330.1 - 0.11 12.0 10.8 1 8.8 0.5 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cauli_AT PF03233.8 KFP05330.1 - 0.14 11.9 5.6 0.26 11.0 0.1 2.3 1 1 0 2 2 2 0 Aphid transmission protein Herpes_UL33 PF03581.8 KFP05330.1 - 0.14 12.0 1.0 0.97 9.3 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus UL33-like protein HAUS-augmin3 PF14932.1 KFP05330.1 - 0.2 10.7 11.5 0.068 12.3 0.4 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 MerR-DNA-bind PF09278.6 KFP05330.1 - 0.5 10.8 4.2 0.54 10.6 0.3 2.6 2 1 1 3 3 3 0 MerR, DNA binding Noelin-1 PF12308.3 KFP05330.1 - 1 9.1 4.5 0.4 10.4 0.3 2.2 2 1 1 3 3 3 0 Neurogenesis glycoprotein Sipho_Gp157 PF05565.6 KFP05330.1 - 1.1 8.8 6.2 0.21 11.1 0.5 2.3 2 1 0 2 2 2 0 Siphovirus Gp157 TMF_TATA_bd PF12325.3 KFP05330.1 - 1.2 8.9 10.0 2.5 7.8 0.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding 4HB_MCP_1 PF12729.2 KFP05330.1 - 2.1 7.6 7.3 0.43 9.9 1.1 2.3 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction Fib_alpha PF08702.5 KFP05330.1 - 2.4 8.3 12.2 3.1 7.9 2.8 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MAT1 PF06391.8 KFP05330.1 - 3.5 7.1 8.2 2.1 7.8 1.3 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 CorA PF01544.13 KFP05330.1 - 3.6 6.5 9.7 3.1 6.7 0.7 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HisKA PF00512.20 KFP05330.1 - 3.7 7.6 5.9 1.3 9.0 1.1 2.3 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TBPIP PF07106.8 KFP05330.1 - 8.3 5.9 11.1 1.1 8.7 1.1 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 7tm_4 PF13853.1 KFP05331.1 - 1.9e-60 202.8 11.9 1.9e-60 202.8 8.2 2.0 2 1 0 2 2 2 1 Olfactory receptor 7tm_1 PF00001.16 KFP05331.1 - 3.5e-14 52.5 11.2 4.8e-14 52.1 7.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Reticulon PF02453.12 KFP05331.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.8 3 1 0 3 3 3 0 Reticulon Cadherin PF00028.12 KFP05332.1 - 5.5e-83 273.3 2.3 2.1e-18 66.3 0.0 5.3 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFP05332.1 - 9e-52 175.0 0.4 9e-52 175.0 0.3 1.7 2 0 0 2 2 2 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFP05332.1 - 5.7e-05 22.5 0.0 1.1 8.8 0.0 4.2 4 0 0 4 4 4 2 Cadherin-like O-antigen_lig PF13425.1 KFP05332.1 - 0.046 13.7 0.9 0.1 12.5 0.6 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein 7tm_1 PF00001.16 KFP05333.1 - 5.2e-39 133.9 34.5 2.1e-37 128.6 23.9 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05333.1 - 1.2e-10 40.9 34.0 2.4e-10 40.0 23.6 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx UPF0489 PF12640.2 KFP05334.1 - 5.2e-47 160.0 0.2 1.1e-46 159.0 0.1 1.6 1 0 0 1 1 1 1 UPF0489 domain Ribonucleas_3_3 PF14622.1 KFP05335.1 - 9.2e-43 145.2 8.6 4.5e-24 84.8 0.0 3.5 4 0 0 4 4 4 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KFP05335.1 - 3e-42 143.6 2.5 4.5e-21 75.4 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease III domain dsrm PF00035.20 KFP05335.1 - 9e-14 51.8 0.0 9e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif 5_3_exonuc PF01367.15 KFP05335.1 - 0.14 12.4 0.1 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Cadherin PF00028.12 KFP05336.1 - 1.8e-76 252.4 10.4 5.3e-19 68.2 0.1 5.4 5 0 0 5 5 5 5 Cadherin domain Cadherin_C PF01049.12 KFP05336.1 - 1.1e-57 194.2 0.9 2.7e-57 192.9 0.6 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin_2 PF08266.7 KFP05336.1 - 0.00029 20.3 0.0 2.6 7.6 0.0 3.8 3 1 0 3 3 3 2 Cadherin-like ASFV_J13L PF05568.6 KFP05336.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein 7TM_GPCR_Srw PF10324.4 KFP05336.1 - 0.11 11.6 0.2 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Peptidase_S8 PF00082.17 KFP05337.1 - 4.1e-59 200.0 1.2 5.5e-59 199.6 0.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFP05337.1 - 4.7e-30 103.2 0.4 8.3e-30 102.4 0.3 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Proho_convert PF12177.3 KFP05337.1 - 3.3e-24 84.1 2.0 3.3e-24 84.1 1.4 2.3 2 0 0 2 2 2 1 Prohormone convertase enzyme Calpain_inhib PF00748.14 KFP05340.1 - 1.8e-127 419.9 98.7 5.4e-40 136.8 12.6 6.2 5 1 1 6 6 6 5 Calpain inhibitor Peptidase_M1 PF01433.15 KFP05341.1 - 2.2e-131 438.5 0.0 2.8e-131 438.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFP05341.1 - 1.7e-47 162.2 0.0 2.4e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFP05341.1 - 2.6e-15 56.6 0.1 5.3e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Pkinase PF00069.20 KFP05342.1 - 8.9e-74 247.9 0.0 1.7e-73 246.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05342.1 - 1.1e-38 132.8 0.0 1.8e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFP05342.1 - 2.6e-13 49.1 0.1 5e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 KFP05342.1 - 2e-06 26.9 0.0 3.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP05342.1 - 7.5e-06 25.8 0.0 0.023 14.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP05342.1 - 4.6e-05 22.5 0.1 9.7e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP05342.1 - 0.013 14.8 0.1 0.03 13.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 KFP05342.1 - 0.032 13.8 0.1 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 Choline/ethanolamine kinase PAX PF00292.13 KFP05345.1 - 2.5e-73 243.6 0.7 4e-73 243.0 0.5 1.3 1 0 0 1 1 1 1 'Paired box' domain Pax2_C PF12403.3 KFP05345.1 - 3e-42 142.9 7.1 3e-42 142.9 4.9 2.1 2 0 0 2 2 2 1 Paired-box protein 2 C terminal HTH_29 PF13551.1 KFP05345.1 - 6.3e-05 23.0 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KFP05345.1 - 9.1e-05 21.9 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 KFP05345.1 - 0.0057 17.4 0.1 0.13 13.0 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.2 KFP05345.1 - 0.017 14.4 0.3 0.078 12.4 0.0 2.0 2 0 0 2 2 2 0 InsA C-terminal domain Ribosomal_S13_N PF08069.7 KFP05345.1 - 0.049 13.4 0.1 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Homeobox PF00046.24 KFP05345.1 - 0.081 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Homeobox domain zf-CCHC PF00098.18 KFP05347.1 - 6.7e-12 44.7 42.9 3.3e-07 29.9 0.8 5.9 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.1 KFP05347.1 - 0.00015 21.3 37.0 0.0009 18.9 2.8 5.1 1 1 3 4 4 4 3 Zinc knuckle RIG-I_C-RD PF11648.3 KFP05347.1 - 0.0092 15.8 2.3 0.06 13.2 0.6 2.2 2 0 0 2 2 2 1 C-terminal domain of RIG-I zf-CCHC_4 PF14392.1 KFP05347.1 - 0.067 12.8 0.4 0.067 12.8 0.3 5.0 4 1 1 5 5 5 0 Zinc knuckle Zn_ribbon_2 PF12674.2 KFP05347.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.5 2 1 1 3 3 3 0 Putative zinc ribbon domain zf-CCHC_2 PF13696.1 KFP05347.1 - 5.8 6.4 34.9 1.6 8.3 2.7 5.2 3 1 2 5 5 5 0 Zinc knuckle 2-Hacid_dh_C PF02826.14 KFP05348.1 - 1.6e-60 203.3 0.0 1.9e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFP05348.1 - 6.3e-08 32.6 0.0 9.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.25 KFP05348.1 - 1.2e-07 31.2 0.0 1.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 KFP05348.1 - 8.4e-07 29.3 0.0 1.6e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KFP05348.1 - 0.0052 16.1 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 KFP05348.1 - 0.029 14.1 0.1 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.15 KFP05348.1 - 0.037 14.1 0.0 0.096 12.7 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KFP05348.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain BTB PF00651.26 KFP05349.1 - 1.9e-29 101.8 1.1 4e-29 100.8 0.7 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.3 KFP05349.1 - 0.0042 16.2 0.1 0.0079 15.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Rota_NS35 PF02509.9 KFP05349.1 - 0.024 13.3 0.1 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 RNA_pol_I_A49 PF06870.7 KFP05350.1 - 9.3e-95 317.4 0.1 3e-78 263.0 0.1 2.0 2 0 0 2 2 2 2 A49-like RNA polymerase I associated factor Mito_carr PF00153.22 KFP05351.1 - 3.7e-32 109.8 0.1 4.8e-12 45.4 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KFP05352.1 - 4.9e-21 73.7 10.3 2e-06 27.4 0.4 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat CMD PF02627.15 KFP05353.1 - 1.8e-13 50.1 0.1 2.1e-12 46.7 0.0 2.0 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family PA26 PF04636.8 KFP05353.1 - 0.086 11.5 0.0 0.17 10.5 0.0 1.5 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1961 PF09224.6 KFP05353.1 - 0.094 11.7 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) Integrase_Zn PF02022.14 KFP05353.1 - 0.1 12.0 0.3 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain tRNA_m1G_MT PF01746.16 KFP05354.1 - 1.8e-24 86.3 0.0 2e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Opiods_neuropep PF01160.13 KFP05355.1 - 5.1e-20 70.9 1.8 7.8e-20 70.3 1.2 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide Op_neuropeptide PF08035.6 KFP05355.1 - 5e-07 29.1 37.8 0.013 15.0 0.3 7.3 7 0 0 7 7 7 7 Opioids neuropeptide RVT_1 PF00078.22 KFP05356.1 - 8.3e-15 54.7 0.0 2.3e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 KFP05357.1 - 7.9e-10 38.2 1.5 2e-05 24.2 1.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat RVT_1 PF00078.22 KFP05358.1 - 0.0051 16.1 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNF111_N PF15303.1 KFP05359.1 - 1.1e-65 221.7 33.9 1.4e-64 218.2 23.5 2.0 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus ATP-synt_ab PF00006.20 KFP05360.1 - 1.6e-72 243.5 0.0 2.4e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFP05360.1 - 1.3e-27 96.4 0.5 2.7e-27 95.4 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFP05360.1 - 2e-18 66.3 1.9 5.3e-18 65.0 1.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.1 KFP05360.1 - 0.0019 18.2 2.5 0.0038 17.2 1.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) HAS-barrel PF09378.5 KFP05360.1 - 0.016 15.1 1.7 0.091 12.6 1.2 2.2 1 1 0 1 1 1 0 HAS barrel domain DUF2042 PF09743.4 KFP05361.1 - 1.1e-100 336.4 0.3 1.1e-100 336.4 0.2 2.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2042) LIM PF00412.17 KFP05362.1 - 1.4e-46 156.4 64.7 3.5e-13 49.3 4.7 5.1 5 0 0 5 5 5 5 LIM domain 7tm_1 PF00001.16 KFP05363.1 - 1.2e-49 168.7 24.2 1.7e-49 168.3 16.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05363.1 - 6.4e-07 28.7 25.1 1.2e-06 27.8 17.4 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF756 PF05506.7 KFP05363.1 - 0.071 13.6 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF756) zf-LITAF-like PF10601.4 KFP05363.1 - 6.4 6.7 9.6 18 5.2 0.5 3.5 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain UPF0240 PF06784.6 KFP05364.1 - 1.8e-37 128.7 0.2 2e-37 128.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) NAP PF00956.13 KFP05364.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Kelch_1 PF01344.20 KFP05365.1 - 4.1e-39 131.8 8.5 5.4e-08 32.2 0.0 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFP05365.1 - 3.6e-35 118.6 4.9 7.7e-08 32.1 0.0 6.9 2 1 4 6 6 6 5 Kelch motif BTB PF00651.26 KFP05365.1 - 2.4e-27 95.0 1.5 1.5e-26 92.5 0.2 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.1 KFP05365.1 - 5.2e-20 70.9 4.6 0.0037 16.9 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain BACK PF07707.10 KFP05365.1 - 3.3e-17 62.2 1.5 7.8e-17 61.0 1.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.10 KFP05365.1 - 5.3e-16 57.6 3.3 0.028 14.2 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 KFP05365.1 - 7.1e-16 57.8 6.1 0.00099 19.2 0.0 7.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP05365.1 - 2.5e-15 56.0 3.0 0.034 14.1 0.1 6.5 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.1 KFP05365.1 - 0.036 14.3 0.5 35 4.8 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain Pou PF00157.12 KFP05367.1 - 3.8e-39 132.1 0.3 6.9e-39 131.3 0.2 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFP05367.1 - 1.8e-19 69.1 0.3 4.2e-19 67.9 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 KFP05367.1 - 4.1e-05 23.6 0.0 0.01 16.0 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain Homeobox_KN PF05920.6 KFP05367.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain F-box-like PF12937.2 KFP05368.1 - 2.7e-08 33.4 2.8 1.4e-07 31.1 1.9 2.4 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KFP05368.1 - 2.8e-08 33.1 11.7 0.038 13.6 0.0 6.0 2 1 4 7 7 7 5 Leucine Rich repeats (2 copies) F-box PF00646.28 KFP05368.1 - 4.4e-08 32.5 0.4 4.4e-08 32.5 0.3 2.8 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 KFP05368.1 - 1.7e-07 30.9 15.3 0.0056 16.4 0.7 5.6 2 1 5 7 7 7 6 Leucine rich repeat LRR_6 PF13516.1 KFP05368.1 - 9.5e-07 28.2 16.8 0.25 11.5 0.0 8.0 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 KFP05368.1 - 7.8e-06 25.2 10.9 6.3 7.2 0.0 8.1 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 KFP05368.1 - 0.00059 19.6 13.4 8.3 7.1 0.0 7.9 6 2 1 7 7 7 2 Leucine rich repeat PRANC PF09372.5 KFP05368.1 - 0.042 13.8 0.2 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 PRANC domain Adeno_E3_CR2 PF02439.10 KFP05368.1 - 0.22 11.1 0.9 0.41 10.2 0.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GST_C_3 PF14497.1 KFP05369.1 - 4e-19 68.9 0.0 8.8e-19 67.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFP05369.1 - 1.2e-05 25.1 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KFP05369.1 - 0.00088 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.1 KFP05369.1 - 0.0016 18.6 0.0 0.043 14.0 0.0 2.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.1 KFP05370.1 - 6.8e-23 81.1 0.0 9.8e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP05370.1 - 3.2e-18 65.9 0.0 5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP05370.1 - 3.8e-16 59.0 0.0 4.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP05370.1 - 4.5e-15 55.9 0.0 7.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP05370.1 - 1.8e-12 47.7 0.0 2.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFP05370.1 - 2.5e-08 33.3 0.0 3.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KFP05370.1 - 4.8e-07 30.0 0.0 7.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFP05370.1 - 7.4e-07 28.5 0.0 1.1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFP05370.1 - 2.2e-05 23.8 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 KFP05370.1 - 2.3e-05 23.8 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 KFP05370.1 - 4.3e-05 22.7 0.0 7.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFP05370.1 - 0.0001 22.2 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFP05370.1 - 0.00072 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 KFP05370.1 - 0.00086 18.0 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.7 KFP05370.1 - 0.0041 16.4 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.9 KFP05370.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KFP05370.1 - 0.13 11.9 0.1 0.46 10.1 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain UCH PF00443.24 KFP05372.1 - 3.2e-49 167.4 2.2 5.5e-49 166.6 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFP05372.1 - 1.6e-17 63.3 10.0 1.6e-17 63.3 6.9 2.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFP05372.1 - 4.2e-15 55.9 9.6 7.8e-12 45.2 6.6 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase THOC7 PF05615.8 KFP05372.1 - 0.0052 17.0 0.9 0.014 15.6 0.6 1.7 1 0 0 1 1 1 1 Tho complex subunit 7 Rhodanese PF00581.15 KFP05373.1 - 1e-07 32.2 0.0 1.1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Cyclin_N PF00134.18 KFP05374.1 - 9.6e-15 54.2 2.9 1e-12 47.7 0.5 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP05374.1 - 0.00093 19.1 1.0 0.028 14.3 0.0 2.8 1 1 1 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.14 KFP05374.1 - 0.01 15.6 0.2 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat SIM_C PF06621.7 KFP05375.1 - 5.7e-121 403.5 17.1 8.3e-121 403.0 11.9 1.2 1 0 0 1 1 1 1 Single-minded protein C-terminus PAS_3 PF08447.6 KFP05375.1 - 9.5e-20 70.4 1.5 3.8e-13 49.3 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 KFP05375.1 - 1.8e-19 69.7 0.1 1.7e-13 50.4 0.0 2.9 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 KFP05375.1 - 7.9e-16 57.8 0.0 5.8e-12 45.3 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KFP05375.1 - 1.4e-06 28.6 0.0 0.075 13.4 0.0 2.8 3 0 0 3 3 3 2 PAS domain HLH PF00010.21 KFP05375.1 - 2.7e-06 26.9 1.0 3.8e-05 23.2 0.5 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.5 KFP05375.1 - 9.8e-06 25.5 0.0 0.025 14.6 0.0 2.8 3 0 0 3 3 3 2 PAS fold Sec63 PF02889.11 KFP05376.1 - 2.3e-177 588.8 1.1 3.7e-108 361.4 0.1 2.8 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 KFP05376.1 - 2.8e-56 189.6 1.5 3.7e-28 98.1 0.4 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KFP05376.1 - 1.5e-17 64.0 0.1 3.6e-08 33.4 0.1 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFP05376.1 - 2.6e-12 46.4 0.0 6.8e-07 29.0 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFP05376.1 - 1.9e-06 28.0 1.2 0.04 14.0 0.0 3.5 3 1 0 3 3 3 2 AAA domain T2SE PF00437.15 KFP05376.1 - 0.00013 21.0 0.0 0.57 9.0 0.0 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein PhoH PF02562.11 KFP05376.1 - 0.00021 20.5 0.1 0.22 10.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 KFP05376.1 - 0.0042 16.8 0.0 1.9 8.2 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 KFP05376.1 - 0.0042 16.5 0.4 0.36 10.2 0.0 3.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_10 PF12846.2 KFP05376.1 - 0.016 14.6 0.1 2.7 7.3 0.0 3.3 3 1 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 KFP05376.1 - 1.7 8.9 5.6 10 6.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain Flavoprotein PF02441.14 KFP05378.1 - 2.4e-47 159.7 0.0 2.9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein SCAMP PF04144.8 KFP05379.1 - 4e-75 251.5 12.0 4.7e-75 251.3 8.3 1.0 1 0 0 1 1 1 1 SCAMP family Chloroplast_duf PF14476.1 KFP05379.1 - 0.12 11.0 1.4 0.2 10.4 0.9 1.3 1 0 0 1 1 1 0 Petal formation-expressed Alba PF01918.16 KFP05380.1 - 1.6e-16 59.6 1.0 2.1e-16 59.2 0.7 1.2 1 0 0 1 1 1 1 Alba COX5A PF02284.11 KFP05381.1 - 4.9e-57 190.5 0.0 5.5e-57 190.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va PMI_typeI PF01238.16 KFP05382.1 - 2.7e-128 428.0 0.0 3.4e-128 427.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I SCAMP PF04144.8 KFP05383.1 - 5.9e-78 260.7 13.3 7.1e-78 260.5 9.2 1.1 1 0 0 1 1 1 1 SCAMP family Wzz PF02706.10 KFP05383.1 - 0.13 12.0 0.1 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Chain length determinant protein UPF0542 PF15086.1 KFP05383.1 - 0.21 11.3 0.8 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 KfrA_N PF11740.3 KFP05383.1 - 9.9 6.6 15.9 0.53 10.7 7.2 1.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Pkinase PF00069.20 KFP05384.1 - 1.8e-63 214.1 0.0 2.6e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05384.1 - 4.4e-39 134.1 0.0 6.1e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.13 KFP05384.1 - 2.2e-35 120.3 14.0 2.1e-21 75.5 1.4 2.7 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Kdo PF06293.9 KFP05384.1 - 2.4e-05 23.5 0.1 6.9e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFP05384.1 - 0.0026 17.3 0.0 0.0072 15.9 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KFP05384.1 - 0.0087 15.8 2.0 0.013 15.2 0.0 2.2 2 2 0 2 2 2 1 Phosphotransferase enzyme family Synaphin PF05835.7 KFP05385.1 - 1.6e-38 132.0 11.2 1.8e-38 131.8 7.8 1.0 1 0 0 1 1 1 1 Synaphin protein AHSP PF09236.5 KFP05385.1 - 0.072 13.2 1.4 0.16 12.2 1.0 1.5 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein PFEMP PF03011.10 KFP05385.1 - 0.13 12.5 3.4 0.18 12.1 2.2 1.4 1 1 0 1 1 1 0 PFEMP DBL domain Complex1_LYR PF05347.10 KFP05385.1 - 0.21 11.4 1.9 0.5 10.1 0.8 1.9 1 1 1 2 2 2 0 Complex 1 protein (LYR family) PRP38_assoc PF12871.2 KFP05385.1 - 9 6.9 7.9 3.1 8.4 2.2 2.2 2 1 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Pkinase_Tyr PF07714.12 KFP05386.1 - 2e-78 263.0 0.2 1.9e-59 200.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KFP05386.1 - 1.2e-40 139.2 0.0 5.7e-38 130.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP05386.1 - 7e-24 83.4 0.1 1.5e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFP05386.1 - 1.8e-13 49.6 0.0 3.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP05386.1 - 2.8e-09 36.4 0.0 6.2e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP05386.1 - 1.5e-06 27.5 0.0 3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 KFP05386.1 - 0.0023 17.7 0.0 0.018 14.7 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFP05386.1 - 0.0023 16.9 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_3 PF08239.6 KFP05386.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain YjeF_N PF03853.10 KFP05387.1 - 7.7e-18 64.6 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KFP05387.1 - 1.7e-12 47.7 0.0 3.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.2 KFP05387.1 - 4.4e-12 45.6 0.0 1.5e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Scd6-like Sm domain HIM1 PF08732.5 KFP05387.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 HIM1 Pkinase PF00069.20 KFP05388.1 - 4.1e-56 190.0 0.3 5.6e-56 189.5 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05388.1 - 9.1e-23 80.6 0.2 3.4e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase ARID PF01388.16 KFP05389.1 - 6.5e-21 74.0 0.1 1.1e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Enkurin PF13864.1 KFP05389.1 - 0.049 13.8 1.0 0.082 13.1 0.7 1.3 1 0 0 1 1 1 0 Calmodulin-binding Yae1_N PF09811.4 KFP05390.1 - 1.8e-12 46.5 32.8 5.1 6.7 22.7 3.3 1 1 0 1 1 1 1 Essential protein Yae1, N terminal RUN PF02759.14 KFP05391.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 RUN domain DUF4206 PF13901.1 KFP05392.1 - 2.3e-59 200.3 1.4 4.2e-59 199.4 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) PH PF00169.24 KFP05392.1 - 6.6e-05 23.0 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 PH domain Prok-RING_2 PF14445.1 KFP05392.1 - 1.2 9.1 10.2 0.77 9.7 0.6 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 2 GCIP PF13324.1 KFP05393.1 - 1.3e-07 31.1 0.1 1.4e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting FAM163 PF15069.1 KFP05393.1 - 0.048 14.2 1.2 0.057 13.9 0.8 1.3 1 1 0 1 1 1 0 FAM163 family EphA2_TM PF14575.1 KFP05393.1 - 0.12 12.7 0.2 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_S19e PF01090.14 KFP05394.1 - 8e-21 73.9 0.3 8.3e-13 47.9 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein S19e HTH_12 PF08461.5 KFP05394.1 - 0.031 14.0 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain ANF_receptor PF01094.23 KFP05395.1 - 1.1e-73 248.0 0.1 1.3e-73 247.8 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Lig_chan-Glu_bd PF10613.4 KFP05395.1 - 2.1e-29 101.2 0.4 5.3e-29 99.9 0.1 1.9 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site Peripla_BP_6 PF13458.1 KFP05395.1 - 4.9e-10 39.2 0.0 7.2e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein NUDE_C PF04880.8 KFP05396.1 - 1.4e-70 237.0 0.9 1.4e-70 237.0 0.6 2.8 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region HALZ PF02183.13 KFP05396.1 - 0.0081 15.8 2.4 0.0081 15.8 1.7 3.2 3 0 0 3 3 3 1 Homeobox associated leucine zipper LXG PF04740.7 KFP05396.1 - 0.019 14.7 12.9 0.022 14.5 6.8 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily CCDC92 PF14916.1 KFP05396.1 - 0.34 10.5 7.9 0.59 9.7 0.0 3.4 2 1 1 3 3 3 0 Coiled-coil domain of unknown function ERM PF00769.14 KFP05396.1 - 0.47 9.9 30.9 0.07 12.6 9.3 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.1 KFP05396.1 - 0.48 9.5 27.5 1.7 7.7 2.9 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 KFP05396.1 - 0.56 10.5 19.4 4 7.8 3.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 KFP05396.1 - 1.1 9.0 28.8 0.058 13.1 5.6 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Sigma54_AID PF00309.15 KFP05396.1 - 1.4 8.4 6.4 0.32 10.5 0.4 2.7 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) CENP-F_leu_zip PF10473.4 KFP05396.1 - 1.4 8.7 30.8 0.55 10.0 16.3 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.4 KFP05396.1 - 2.1 8.3 14.5 0.098 12.5 2.4 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein DUF904 PF06005.7 KFP05396.1 - 3.5 7.9 31.4 3.2 8.1 3.5 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF4407 PF14362.1 KFP05396.1 - 4 6.2 17.4 8.6 5.2 12.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 KFP05396.1 - 4.3 7.1 30.2 33 4.2 15.1 3.3 1 1 1 2 2 2 0 Tropomyosin like Rootletin PF15035.1 KFP05396.1 - 4.6 7.1 32.2 4 7.3 8.4 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.7 KFP05396.1 - 6 6.6 9.9 13 5.5 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 KFP05396.1 - 7.1 6.7 0.0 7.1 6.7 0.0 5.9 6 1 0 6 6 6 0 Viral A-type inclusion protein repeat HCO3_cotransp PF00955.16 KFP05398.1 - 5.4e-214 711.5 7.6 7.6e-214 711.0 5.2 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFP05398.1 - 5.8e-82 275.0 0.0 8.1e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain PTS_EIIA_2 PF00359.17 KFP05398.1 - 0.025 14.2 0.0 0.065 12.9 0.0 1.6 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF4200 PF13863.1 KFP05399.1 - 9.8e-23 80.4 30.2 9.8e-23 80.4 20.9 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Arabinose_Isome PF02610.10 KFP05399.1 - 0.37 9.6 11.0 0.14 11.0 5.6 1.7 1 1 1 2 2 2 0 L-arabinose isomerase V-set PF07686.12 KFP05400.1 - 2.4e-05 24.2 0.2 4.2e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Immunoglobulin V-set domain Septin PF00735.13 KFP05401.1 - 3.2e-111 370.8 2.9 3.6e-111 370.7 2.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFP05401.1 - 1.5e-09 37.8 0.2 4.5e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP05401.1 - 4e-07 29.3 0.4 8.6e-07 28.2 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFP05401.1 - 4e-06 26.7 2.1 0.0018 18.1 0.4 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KFP05401.1 - 8e-06 25.4 0.8 4.9e-05 22.8 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KFP05401.1 - 1.1e-05 24.7 0.1 1.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KFP05401.1 - 5.7e-05 23.5 0.1 0.00015 22.2 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFP05401.1 - 9.4e-05 21.8 0.2 0.00033 20.0 0.0 2.0 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 KFP05401.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain IIGP PF05049.8 KFP05401.1 - 0.0014 17.5 0.6 0.017 13.9 0.0 2.4 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 KFP05401.1 - 0.0018 18.5 1.3 0.0033 17.7 0.6 1.7 1 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 KFP05401.1 - 0.0027 17.8 0.0 0.0066 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KFP05401.1 - 0.0027 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family PduV-EutP PF10662.4 KFP05401.1 - 0.0034 16.8 0.2 0.079 12.4 0.1 2.4 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KFP05401.1 - 0.0055 15.8 0.2 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KFP05401.1 - 0.0058 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KFP05401.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 KFP05401.1 - 0.017 13.8 1.0 0.034 12.8 0.7 1.8 1 1 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.1 KFP05401.1 - 0.018 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KFP05401.1 - 0.025 14.2 0.1 0.048 13.3 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KFP05401.1 - 0.03 13.9 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KFP05401.1 - 0.03 13.5 0.1 0.062 12.5 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_32 PF13654.1 KFP05401.1 - 0.031 12.9 0.0 0.052 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFP05401.1 - 0.037 13.9 0.2 0.11 12.4 0.0 1.9 2 1 0 2 2 1 0 AAA domain NB-ARC PF00931.17 KFP05401.1 - 0.039 12.8 0.1 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain GBP PF02263.14 KFP05401.1 - 0.04 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain FeoB_N PF02421.13 KFP05401.1 - 0.045 13.0 0.2 0.13 11.4 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.21 KFP05401.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 KFP05401.1 - 0.083 13.1 2.6 1.1 9.5 0.3 2.8 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFP05401.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 KFP05401.1 - 0.15 11.4 0.6 3.6 6.9 0.1 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain M_domain PF12938.2 KFP05402.1 - 1.5e-46 159.1 33.0 1.5e-46 159.1 22.9 9.1 4 2 3 8 8 8 1 M domain of GW182 Ago_hook PF10427.4 KFP05402.1 - 1.7e-17 63.8 27.5 1.7e-17 63.8 19.1 11.9 7 2 5 12 12 12 1 Argonaute hook UBA PF00627.26 KFP05402.1 - 1.2e-06 28.1 0.1 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RRM_5 PF13893.1 KFP05402.1 - 2.9e-06 27.0 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP05402.1 - 0.00029 20.4 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05402.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) THOC7 PF05615.8 KFP05402.1 - 0.22 11.8 3.6 0.39 10.9 2.5 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Ras PF00071.17 KFP05404.1 - 4.7e-39 133.3 0.0 5.4e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP05404.1 - 9e-20 71.3 0.0 1.3e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP05404.1 - 1.4e-09 37.3 0.0 1.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP05404.1 - 1.1e-06 28.1 0.0 2.6e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP05404.1 - 1.4e-05 24.3 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFP05404.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFP05404.1 - 0.0057 16.7 0.1 0.048 13.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFP05404.1 - 0.0063 15.7 0.0 0.013 14.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFP05404.1 - 0.012 15.6 0.2 0.047 13.6 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 KFP05404.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 KFP05404.1 - 0.027 14.1 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 KFP05404.1 - 0.11 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PRELI PF04707.9 KFP05405.1 - 1.1e-52 177.7 0.4 1.7e-52 177.1 0.3 1.3 1 0 0 1 1 1 1 PRELI-like family CRAL_TRIO PF00650.15 KFP05405.1 - 2.1e-41 141.0 0.0 3.8e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFP05405.1 - 9e-09 35.3 0.3 8.1e-08 32.2 0.1 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFP05405.1 - 0.0025 17.7 0.0 0.026 14.4 0.0 2.3 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain Phage_fiber_2 PF03406.8 KFP05405.1 - 0.27 10.8 1.6 0.55 9.9 1.1 1.4 1 0 0 1 1 1 0 Phage tail fibre repeat Glyco_transf_18 PF15024.1 KFP05407.1 - 2.5e-237 788.7 1.5 3e-236 785.1 1.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 18 RRM_1 PF00076.17 KFP05408.1 - 5.2e-18 64.4 0.0 8e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05408.1 - 2.4e-13 49.8 0.0 3.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP05408.1 - 9.7e-07 28.5 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFP05408.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1777 PF08648.7 KFP05408.1 - 0.079 12.6 55.3 0.072 12.8 37.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Methyltransf_16 PF10294.4 KFP05409.1 - 3.5e-07 29.8 0.0 0.00016 21.1 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase JmjC PF02373.17 KFP05410.1 - 1.2e-29 102.8 0.0 2.4e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KFP05410.1 - 7.9e-21 74.6 0.1 1.3e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain SR-25 PF10500.4 KFP05410.1 - 0.53 9.7 13.8 1.1 8.6 9.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.8 KFP05410.1 - 2.9 5.6 17.5 4 5.1 12.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_transf_29 PF00777.13 KFP05411.1 - 1.7e-64 217.5 0.0 1.9e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Globin PF00042.17 KFP05412.1 - 1.4e-24 86.5 0.1 2.2e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Globin DUF592 PF04574.8 KFP05412.1 - 0.062 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Acetyltransf_1 PF00583.19 KFP05413.1 - 1.6e-12 47.2 0.0 2.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFP05413.1 - 1.2e-07 31.7 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFP05413.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFP05413.1 - 0.026 14.3 0.0 0.081 12.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.21 KFP05414.1 - 2.1e-22 79.0 0.0 4.7e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DAGK_cat PF00781.19 KFP05415.1 - 1.7e-21 75.9 0.0 2.3e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pribosyl_synth PF14572.1 KFP05416.1 - 3.6e-102 339.7 0.5 3.6e-102 339.7 0.4 1.6 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFP05416.1 - 8.9e-37 125.3 0.2 1.8e-36 124.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFP05416.1 - 0.00018 21.2 2.5 0.00096 18.8 1.1 2.6 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Viral_env_E26 PF11050.3 KFP05416.1 - 0.099 11.8 0.1 0.21 10.7 0.1 1.5 1 0 0 1 1 1 0 Virus envelope protein E26 SseC PF04888.7 KFP05417.1 - 0.37 10.0 2.7 25 4.0 0.0 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family NPV_P10 PF05531.7 KFP05417.1 - 7.6 6.8 10.6 2.4 8.4 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_3 PF13920.1 KFP05418.1 - 3.6e-08 32.9 6.6 8.5e-08 31.7 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP05418.1 - 7.6e-05 22.6 8.2 0.00018 21.4 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Fork_head PF00250.13 KFP05419.1 - 2.1e-38 130.2 0.1 3.8e-38 129.4 0.1 1.4 1 0 0 1 1 1 1 Fork head domain Exo70 PF03081.10 KFP05420.1 - 1.2e-81 274.4 2.3 1.2e-81 274.4 1.6 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit GIT1_C PF12205.3 KFP05420.1 - 0.0021 17.8 0.4 0.052 13.3 0.0 2.6 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term Vps52 PF04129.7 KFP05420.1 - 0.014 13.9 4.3 0.24 9.8 0.9 2.3 2 0 0 2 2 2 0 Vps52 / Sac2 family Scaffolding_pro PF11418.3 KFP05420.1 - 0.02 15.2 1.2 0.56 10.5 0.1 3.4 3 0 0 3 3 3 0 Phi29 scaffolding protein HTH_Crp_2 PF13545.1 KFP05420.1 - 0.076 12.8 0.1 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain COG5 PF10392.4 KFP05420.1 - 1.9 8.4 10.2 0.031 14.2 1.2 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 BAG PF02179.11 KFP05420.1 - 2 8.5 9.0 19 5.4 0.1 4.6 6 0 0 6 6 6 0 BAG domain 7tm_1 PF00001.16 KFP05421.1 - 2e-61 207.3 21.7 2.3e-61 207.1 15.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.4 KFP05421.1 - 7.3e-13 48.3 18.1 3e-11 43.0 12.6 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srsx PF10320.4 KFP05421.1 - 6e-11 41.9 19.7 7e-11 41.7 13.7 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP05421.1 - 0.00023 20.3 24.8 0.001 18.2 17.2 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx SecG PF03840.9 KFP05421.1 - 0.001 18.7 2.6 1.2 8.9 0.0 3.4 3 0 0 3 3 3 2 Preprotein translocase SecG subunit SUR7 PF06687.7 KFP05421.1 - 0.048 13.2 0.5 0.048 13.2 0.3 3.2 3 2 0 3 3 3 0 SUR7/PalI family MutS_III PF05192.13 KFP05422.1 - 0.00014 21.7 1.8 0.016 14.9 0.6 3.0 1 1 0 2 2 2 1 MutS domain III TPR_6 PF13174.1 KFP05422.1 - 0.0012 19.1 3.1 1.8 9.2 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFP05422.1 - 0.018 14.6 2.3 0.82 9.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFP05422.1 - 0.45 10.5 11.7 0.41 10.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFP05422.1 - 1.9 8.4 13.4 0.5 10.3 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFP05422.1 - 2.6 8.2 7.5 12 6.1 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Plectin PF00681.15 KFP05423.1 - 2.6e-51 170.8 1.0 9.7e-15 53.8 0.1 7.5 5 1 2 7 7 7 6 Plectin repeat Ten1_2 PF15490.1 KFP05424.1 - 4.6e-42 142.3 0.0 5.1e-42 142.1 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit ACOX PF01756.14 KFP05425.1 - 1.6e-66 223.2 0.6 2.5e-66 222.6 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KFP05425.1 - 2.5e-27 95.6 0.3 7.8e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KFP05425.1 - 5.3e-07 29.0 0.1 1.1e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFP05425.1 - 0.0033 17.5 0.0 0.01 15.9 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain QRPTase_C PF01729.14 KFP05426.1 - 2e-23 82.7 0.0 2.2e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain DUF1537 PF07005.6 KFP05426.1 - 0.0058 16.3 0.2 0.007 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 PIRT PF15099.1 KFP05427.1 - 7.9e-49 164.1 0.1 9.2e-49 163.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Claudin_2 PF13903.1 KFP05427.1 - 0.0049 16.5 0.2 0.0057 16.3 0.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction 7TM_GPCR_Srz PF10325.4 KFP05427.1 - 0.0051 15.9 0.8 0.0059 15.7 0.6 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srz DUF1686 PF07937.6 KFP05427.1 - 0.0085 15.7 0.1 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1686) SdpI PF13630.1 KFP05427.1 - 0.024 14.3 2.6 1.6 8.4 2.1 2.1 1 1 1 2 2 2 0 SdpI/YhfL protein family Neurensin PF14927.1 KFP05427.1 - 0.029 13.7 1.7 0.56 9.5 0.1 2.1 1 1 1 2 2 2 0 Neurensin DUF2663 PF10864.3 KFP05427.1 - 0.036 14.2 0.2 0.049 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) YajC PF02699.10 KFP05427.1 - 0.037 13.6 0.3 0.073 12.7 0.2 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF1469 PF07332.6 KFP05427.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) NfeD PF01957.13 KFP05427.1 - 0.097 12.8 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding PI3K_1B_p101 PF10486.4 KFP05428.1 - 1.3e-65 221.5 0.4 1.4e-65 221.4 0.3 1.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Laminin_N PF00055.12 KFP05429.1 - 1.2e-31 109.4 0.0 2.6e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) NTR PF01759.16 KFP05429.1 - 6.7e-31 106.1 1.3 1.7e-30 104.8 0.9 1.7 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.19 KFP05429.1 - 1.9e-10 40.4 14.6 1.9e-10 40.4 10.1 3.4 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) F5_F8_type_C PF00754.20 KFP05429.1 - 0.00023 21.0 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain DUF3217 PF11506.3 KFP05429.1 - 0.13 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) SNARE PF05739.14 KFP05430.1 - 6.8e-14 51.3 5.7 6.8e-14 51.3 3.9 2.3 2 0 0 2 2 2 1 SNARE domain Baculo_PEP_C PF04513.7 KFP05430.1 - 0.0069 16.2 5.0 0.056 13.2 0.1 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus KH_5 PF13184.1 KFP05430.1 - 0.063 13.0 3.0 9.2 6.1 0.2 3.2 2 2 1 3 3 3 0 NusA-like KH domain DUF3802 PF12290.3 KFP05430.1 - 0.55 10.5 3.9 0.45 10.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) DUF2664 PF10867.3 KFP05430.1 - 7.2 7.3 7.9 1.7 9.3 0.8 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2664) TLD PF07534.11 KFP05431.1 - 3.3e-29 101.6 0.0 2.5e-15 56.7 0.0 2.4 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.13 KFP05431.1 - 8.1e-23 81.0 0.3 1.5e-22 80.1 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 KFP05432.1 - 3.1e-45 150.4 29.0 7.1e-07 28.8 0.0 11.4 12 0 0 12 12 12 8 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFP05432.1 - 4.5e-05 22.3 1.8 0.72 8.5 0.1 4.1 2 1 1 3 3 3 2 Nup133 N terminal like Lgl_C PF08596.5 KFP05432.1 - 0.00079 18.0 0.1 0.0042 15.6 0.0 2.0 1 1 1 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal PQQ_3 PF13570.1 KFP05432.1 - 0.035 14.3 4.1 8.2 6.8 0.0 5.8 7 1 1 8 8 8 0 PQQ-like domain UCH PF00443.24 KFP05433.1 - 2.1e-05 23.7 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BAR PF03114.13 KFP05434.1 - 7e-55 186.0 5.2 1.3e-54 185.1 3.6 1.4 1 0 0 1 1 1 1 BAR domain RhoGAP PF00620.22 KFP05434.1 - 1e-45 155.0 0.1 5.9e-45 152.5 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain p450 PF00067.17 KFP05435.1 - 8.4e-130 433.3 0.1 9.5e-130 433.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2080 PF09853.4 KFP05435.1 - 0.15 11.7 0.6 1.3 8.7 0.0 2.5 3 0 0 3 3 3 0 Putative transposon-encoded protein (DUF2080) DUF846 PF05832.7 KFP05436.1 - 6.2e-55 184.8 8.3 7.4e-55 184.5 5.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM192 PF14802.1 KFP05436.1 - 0.12 11.1 0.4 0.19 10.5 0.3 1.2 1 0 0 1 1 1 0 TMEM192 family PMP22_Claudin PF00822.15 KFP05437.1 - 1.1e-31 109.7 7.9 1.2e-31 109.6 5.5 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP05437.1 - 5.7e-09 35.8 11.7 6.5e-09 35.7 8.1 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2723 PF11028.3 KFP05437.1 - 0.011 15.2 3.6 0.013 14.9 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Amastin PF07344.6 KFP05437.1 - 0.017 14.7 6.6 0.019 14.5 4.6 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF373 PF04123.8 KFP05437.1 - 0.03 13.3 3.1 0.032 13.2 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SUR7 PF06687.7 KFP05437.1 - 0.057 12.9 9.9 0.077 12.5 6.9 1.2 1 0 0 1 1 1 0 SUR7/PalI family L_HGMIC_fpl PF10242.4 KFP05437.1 - 0.065 13.2 7.2 0.043 13.8 4.0 1.4 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein PepSY_TM PF03929.11 KFP05437.1 - 0.069 13.5 0.1 0.069 13.5 0.1 3.0 3 1 0 3 3 3 0 PepSY-associated TM helix Claudin_3 PF06653.6 KFP05437.1 - 0.16 11.6 6.8 0.2 11.3 4.7 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Sugar_tr PF00083.19 KFP05437.1 - 0.17 10.4 6.6 0.19 10.2 4.6 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Clc-like PF07062.7 KFP05437.1 - 0.19 10.9 10.1 0.36 10.0 7.0 1.6 1 1 0 1 1 1 0 Clc-like 7TMR-DISM_7TM PF07695.6 KFP05437.1 - 0.27 10.8 13.8 0.53 9.9 8.3 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling CD20 PF04103.10 KFP05437.1 - 0.4 10.6 6.0 0.72 9.7 0.5 2.1 2 0 0 2 2 2 0 CD20-like family DUF2207 PF09972.4 KFP05437.1 - 0.76 8.2 5.4 0.81 8.1 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3923 PF13061.1 KFP05437.1 - 1.1 9.1 10.3 0.26 11.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) DUF3139 PF11337.3 KFP05437.1 - 2.2 8.6 3.8 20 5.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) DUF4013 PF13197.1 KFP05437.1 - 6.1 6.1 11.8 0.88 8.8 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) Sulfotransfer_1 PF00685.22 KFP05438.1 - 2.7e-31 108.8 0.0 3.2e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFP05438.1 - 0.0057 16.3 0.0 0.052 13.2 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family RICTOR_M PF14666.1 KFP05438.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain UbiA PF01040.13 KFP05439.1 - 7.6e-31 107.2 19.8 1e-30 106.8 13.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CSF-1 PF05337.6 KFP05439.1 - 0.033 13.5 0.1 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) Sulfotransfer_1 PF00685.22 KFP05440.1 - 2.7e-31 108.8 0.0 3.2e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFP05440.1 - 0.0057 16.3 0.0 0.052 13.2 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family RICTOR_M PF14666.1 KFP05440.1 - 0.13 11.2 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain TIMP PF00965.12 KFP05441.1 - 0.0034 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase NTR PF01759.16 KFP05441.1 - 0.03 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Glycos_transf_2 PF00535.21 KFP05442.1 - 5.8e-18 65.1 0.0 1.1e-17 64.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 KFP05442.1 - 8.4e-08 31.6 0.0 1.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KFP05442.1 - 3.3e-07 30.3 0.0 4.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KFP05442.1 - 0.00016 21.9 0.0 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 TFCD_C PF12612.3 KFP05443.1 - 1e-61 207.7 0.5 2.4e-59 199.9 0.0 3.0 3 0 0 3 3 3 2 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 KFP05443.1 - 1.5e-06 28.4 17.2 0.12 12.8 0.0 8.6 8 3 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.1 KFP05443.1 - 0.00021 21.4 4.4 0.088 13.1 0.2 5.4 3 2 2 5 5 5 1 HEAT repeats HEAT PF02985.17 KFP05443.1 - 0.0017 18.2 13.3 0.068 13.2 0.0 8.4 10 1 0 10 10 10 1 HEAT repeat HEAT_PBS PF03130.11 KFP05443.1 - 0.23 12.0 4.6 26 5.6 0.0 5.7 8 0 0 8 8 8 0 PBS lyase HEAT-like repeat zf-C2H2_7 PF15269.1 KFP05444.1 - 1.5e-36 123.9 11.3 4.9e-36 122.3 7.8 1.9 1 0 0 1 1 1 1 Zinc-finger zf-C2H2 PF00096.21 KFP05444.1 - 5.2 7.6 13.0 0.88 10.0 4.7 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Fructosamin_kin PF03881.9 KFP05445.1 - 3.6e-73 246.0 0.0 6.3e-73 245.2 0.0 1.4 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFP05445.1 - 3.3e-15 56.4 0.0 4.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFP05445.1 - 0.00063 19.1 0.0 0.025 13.9 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 KFP05445.1 - 0.0028 16.7 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH_6_hur PF04655.9 KFP05445.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Fructosamin_kin PF03881.9 KFP05446.1 - 3e-69 233.1 0.2 6.9e-69 231.9 0.2 1.5 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFP05446.1 - 5.8e-09 36.0 0.0 7.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFP05446.1 - 0.068 12.5 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.27 KFP05447.1 - 4.6e-06 26.3 1.0 0.13 12.2 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3761 PF12587.3 KFP05447.1 - 0.0026 17.8 0.1 0.0057 16.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3761) Me-amine-dh_H PF06433.6 KFP05447.1 - 0.044 12.4 0.2 5.2 5.5 0.1 2.4 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) DUF1513 PF07433.6 KFP05447.1 - 0.12 11.2 0.0 0.41 9.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) Fork_head PF00250.13 KFP05448.1 - 4.2e-41 138.8 0.2 6.8e-41 138.2 0.2 1.3 1 0 0 1 1 1 1 Fork head domain Fe_hyd_lg_C PF02906.9 KFP05449.1 - 1.5e-82 277.1 0.1 2.2e-82 276.5 0.1 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 KFP05449.1 - 7.3e-11 41.9 1.4 1.2e-10 41.2 0.1 2.0 2 0 0 2 2 2 1 Iron hydrogenase small subunit DUF4564 PF15169.1 KFP05450.1 - 1.6e-80 269.3 0.0 1.7e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) TMEM220 PF15071.1 KFP05450.1 - 0.0083 16.5 0.2 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Transmembrane family 220, helix UbiA PF01040.13 KFP05450.1 - 0.026 13.7 1.5 0.038 13.2 1.0 1.4 1 1 0 1 1 1 0 UbiA prenyltransferase family Glyco_hydro_20 PF00728.17 KFP05451.1 - 3.7e-16 59.2 0.5 6.8e-16 58.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain DUF3279 PF11682.3 KFP05451.1 - 0.035 13.6 0.7 0.18 11.3 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3279) 2OG-FeII_Oxy_3 PF13640.1 KFP05452.1 - 6.3e-20 71.5 0.3 9.7e-20 70.9 0.2 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFP05452.1 - 1.7e-12 46.7 0.6 4.1e-12 45.5 0.4 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.4 KFP05452.1 - 0.016 14.5 0.3 0.37 10.1 0.2 2.3 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA 2OG-FeII_Oxy PF03171.15 KFP05452.1 - 0.051 13.8 0.1 0.087 13.1 0.1 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 7tm_1 PF00001.16 KFP05453.1 - 7.2e-19 67.9 4.6 8.4e-19 67.7 3.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05453.1 - 0.00019 20.6 1.2 0.00025 20.2 0.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFP05453.1 - 0.00044 19.4 1.0 0.00059 19.0 0.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Anticodon_1 PF08264.8 KFP05453.1 - 0.061 13.0 0.4 0.12 12.1 0.2 1.5 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA DUF1129 PF06570.6 KFP05453.1 - 0.087 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Defensin_beta PF00711.14 KFP05454.1 - 3.5e-08 33.2 11.8 4.4e-08 32.9 8.2 1.1 1 0 0 1 1 1 1 Beta defensin Defensin_propep PF00879.13 KFP05454.1 - 0.0011 18.8 3.8 0.0013 18.6 2.6 1.1 1 0 0 1 1 1 1 Defensin propeptide TRAM1 PF08390.6 KFP05456.1 - 3e-22 77.8 0.5 3e-22 77.8 0.4 2.0 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 KFP05456.1 - 1.1e-18 67.5 17.1 2e-18 66.6 11.9 1.4 1 0 0 1 1 1 1 TLC domain RhodobacterPufX PF11511.3 KFP05456.1 - 0.033 13.5 0.0 0.12 11.7 0.0 2.0 1 0 0 1 1 1 0 Intrinsic membrane protein PufX DUF3112 PF11309.3 KFP05456.1 - 0.76 9.5 7.7 5.1 6.8 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) DUF1126 PF06565.7 KFP05457.1 - 5.2e-49 163.3 1.8 3.1e-15 55.3 0.0 3.7 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_1 PF00036.27 KFP05457.1 - 0.058 12.7 0.2 0.21 10.9 0.1 2.1 1 0 0 1 1 1 0 EF hand S_layer_N PF05123.7 KFP05457.1 - 0.14 11.7 0.0 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 S-layer like family, N-terminal region HlyIII PF03006.15 KFP05458.1 - 2.4e-45 154.6 17.8 2.4e-45 154.6 12.3 1.4 2 0 0 2 2 2 1 Haemolysin-III related MCM PF00493.18 KFP05459.1 - 2.1e-128 427.7 0.5 3.1e-128 427.2 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFP05459.1 - 2.5e-13 50.5 0.0 8.5e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFP05459.1 - 1.1e-07 31.2 0.0 6.9e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFP05459.1 - 0.0036 16.9 0.0 0.012 15.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFP05459.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KFP05459.1 - 0.047 13.1 0.0 0.2 11.1 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain U79_P34 PF03064.11 KFP05459.1 - 0.24 10.9 6.0 0.41 10.1 4.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 IL17 PF06083.6 KFP05460.1 - 3.1e-28 97.6 0.1 4.7e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Interleukin-17 IL17 PF06083.6 KFP05461.1 - 4.2e-32 110.0 0.4 7.5e-32 109.2 0.3 1.4 1 0 0 1 1 1 1 Interleukin-17 TF_AP-2 PF03299.9 KFP05462.1 - 3.1e-98 327.4 0.0 8.6e-98 325.9 0.0 1.6 2 0 0 2 2 2 1 Transcription factor AP-2 TF_AP-2 PF03299.9 KFP05463.1 - 4.8e-92 307.2 0.0 6.9e-92 306.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor AP-2 CAP PF00188.21 KFP05464.1 - 4e-22 79.0 8.9 5e-22 78.6 6.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Crisp PF08562.5 KFP05464.1 - 0.065 13.5 7.3 0.065 13.5 5.0 2.0 2 0 0 2 2 2 0 Crisp Crisp PF08562.5 KFP05465.1 - 6.7e-23 80.7 15.9 1.8e-22 79.3 11.0 1.8 1 0 0 1 1 1 1 Crisp CAP PF00188.21 KFP05465.1 - 3.8e-20 72.6 5.2 5.4e-20 72.1 3.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ShK PF01549.19 KFP05465.1 - 0.059 13.7 6.6 0.059 13.7 4.6 3.6 3 1 1 4 4 4 0 ShK domain-like Ammonium_transp PF00909.16 KFP05466.1 - 1.3e-74 251.1 25.4 1.4e-74 250.9 17.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family p450 PF00067.17 KFP05467.1 - 9.3e-118 393.6 1.4 3.6e-117 391.7 0.0 1.9 1 1 0 2 2 2 1 Cytochrome P450 Pox_polyA_pol_N PF12630.2 KFP05467.1 - 0.16 12.0 2.1 0.45 10.6 1.4 1.6 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain CENP-Q PF13094.1 KFP05468.1 - 1.1e-15 58.0 15.6 1.7e-15 57.3 10.8 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin PF00261.15 KFP05468.1 - 0.12 11.4 10.3 0.29 10.1 7.2 1.7 1 1 0 1 1 1 0 Tropomyosin DUF4404 PF14357.1 KFP05468.1 - 0.9 9.9 7.0 2.2 8.7 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Syntaxin-6_N PF09177.6 KFP05468.1 - 1.1 9.7 7.9 8.7 6.8 2.8 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc24 PF08286.6 KFP05468.1 - 1.1 8.9 8.5 0.43 10.2 3.3 2.2 1 1 1 3 3 3 0 Spc24 subunit of Ndc80 ATG16 PF08614.6 KFP05468.1 - 1.2 8.9 13.0 0.45 10.2 7.0 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Kinesin-relat_1 PF12711.2 KFP05468.1 - 1.3 9.4 8.6 0.24 11.8 1.7 2.7 2 1 0 2 2 2 0 Kinesin motor V_ATPase_I PF01496.14 KFP05468.1 - 2.2 6.0 6.2 2.4 5.8 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nsp1_C PF05064.8 KFP05468.1 - 3.1 7.4 13.4 2.8 7.6 4.3 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region MM_CoA_mutase PF01642.17 KFP05469.1 - 3.2e-251 833.9 0.0 3.7e-251 833.7 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 KFP05469.1 - 2.3e-12 46.8 0.2 6.1e-12 45.4 0.1 1.8 2 0 0 2 2 2 1 B12 binding domain PMBR PF09373.5 KFP05469.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Pseudomurein-binding repeat 7tm_1 PF00001.16 KFP05470.1 - 3.9e-39 134.3 14.3 4.6e-39 134.0 9.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP05470.1 - 4e-06 26.1 13.1 7.6e-06 25.2 9.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Bac_rhodopsin PF01036.13 KFP05470.1 - 0.038 13.2 7.7 0.049 12.9 3.6 2.2 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein ChlI PF13541.1 KFP05470.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase DUF1230 PF06799.6 KFP05470.1 - 0.26 11.1 5.9 0.57 10.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) MerB PF03243.10 KFP05470.1 - 0.53 10.1 2.5 0.73 9.6 0.4 2.0 2 0 0 2 2 2 0 Alkylmercury lyase zf-H2C2_2 PF13465.1 KFP05472.1 - 1.5e-27 94.5 85.9 2.2e-07 30.8 3.4 10.2 9 2 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFP05472.1 - 2.9e-18 64.9 78.2 0.0031 17.7 5.9 8.5 9 0 0 9 9 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP05472.1 - 4.1e-10 39.2 68.0 0.0037 17.5 4.2 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP05472.1 - 7.4e-05 22.7 13.7 0.015 15.5 0.1 9.4 9 3 0 9 9 8 5 C2H2-type zinc-finger domain BolA PF01722.13 KFP05472.1 - 0.0036 17.2 3.4 1.5 8.8 0.2 3.1 3 0 0 3 3 3 2 BolA-like protein zf-C2H2_7 PF15269.1 KFP05472.1 - 0.0048 16.7 2.4 0.0048 16.7 1.7 6.6 3 3 4 7 7 6 3 Zinc-finger C1_3 PF07649.7 KFP05472.1 - 0.025 14.5 31.7 0.27 11.3 0.1 6.8 8 0 0 8 8 8 0 C1-like domain DUF2225 PF09986.4 KFP05472.1 - 0.045 13.1 0.3 0.045 13.1 0.2 3.8 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) RNA_pol_L_2 PF13656.1 KFP05472.1 - 0.054 12.9 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain GAGA PF09237.6 KFP05472.1 - 0.12 12.0 12.6 0.23 11.0 0.2 3.9 4 0 0 4 4 4 0 GAGA factor C1_1 PF00130.17 KFP05472.1 - 0.64 9.7 32.1 1.1 8.9 0.6 5.7 4 2 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.3 KFP05472.1 - 1.5 9.0 0.0 0.66 10.1 1.5 7.7 8 0 0 8 8 7 0 Zinc-finger double-stranded RNA-binding DUF1390 PF07150.6 KFP05472.1 - 7.1 5.9 12.9 0.18 11.1 1.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1390) Myb_Cef PF11831.3 KFP05473.1 - 3.2e-75 252.3 4.4 3.2e-75 252.3 3.0 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KFP05473.1 - 9.6e-20 70.3 8.6 1.2e-11 44.4 0.7 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFP05473.1 - 5.6e-18 64.8 10.2 1.3e-13 50.8 3.4 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain TFIID-18kDa PF02269.11 KFP05475.1 - 1.3e-29 101.8 0.1 4.5e-29 100.1 0.2 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit GST_N_3 PF13417.1 KFP05476.1 - 6.4e-09 35.9 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFP05476.1 - 1.3e-06 28.1 0.0 4.4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFP05476.1 - 2e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFP05476.1 - 0.0002 21.7 0.1 0.00048 20.5 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFP05476.1 - 0.0016 18.3 0.7 0.05 13.6 0.0 2.9 2 2 1 3 3 3 1 Glutathione S-transferase, C-terminal domain Phosphodiest PF01663.17 KFP05478.1 - 2.4e-80 270.5 1.2 2.9e-80 270.3 0.8 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFP05478.1 - 6.7e-07 28.7 0.0 0.00022 20.5 0.0 2.4 3 0 0 3 3 3 2 Sulfatase Metalloenzyme PF01676.13 KFP05478.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF1501 PF07394.7 KFP05478.1 - 0.028 13.2 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Phosphodiest PF01663.17 KFP05479.1 - 2.7e-78 263.8 1.6 3.1e-78 263.6 1.1 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFP05479.1 - 5.6e-07 29.0 0.0 0.02 14.0 0.0 2.4 2 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.13 KFP05479.1 - 0.004 16.5 0.0 0.0085 15.5 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily Calcipressin PF04847.7 KFP05480.1 - 2.3e-60 203.3 0.3 2.8e-60 203.0 0.2 1.1 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 KFP05480.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP05480.1 - 0.013 15.1 0.3 0.022 14.3 0.2 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 KFP05481.1 - 1.1e-58 198.9 0.2 1.5e-58 198.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 KFP05482.1 - 6.3e-68 224.5 1.2 2.3e-22 78.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TUDOR PF00567.19 KFP05483.1 - 6.2e-151 494.2 8.0 4.3e-31 107.2 0.2 7.7 7 0 0 7 7 7 7 Tudor domain SMN PF06003.7 KFP05483.1 - 1.3e-12 47.4 0.1 0.0062 15.6 0.0 4.5 4 0 0 4 4 4 4 Survival motor neuron protein (SMN) DUF4537 PF15057.1 KFP05483.1 - 2.6e-10 40.1 0.3 0.36 10.6 0.0 6.2 6 0 0 6 6 6 3 Domain of unknown function (DUF4537) Agenet PF05641.7 KFP05483.1 - 0.0087 16.1 7.0 4.6 7.4 0.0 6.1 7 0 0 7 7 7 1 Agenet domain DUF1325 PF07039.6 KFP05483.1 - 0.031 13.8 0.0 31 4.1 0.0 3.7 4 0 0 4 4 4 0 SGF29 tudor-like domain PAF-AH_p_II PF03403.8 KFP05485.1 - 1.4e-172 573.2 0.0 1.7e-172 572.9 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFP05485.1 - 1.9e-14 53.6 0.0 2.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFP05485.1 - 8.5e-09 34.6 0.1 4.7e-07 28.9 0.1 2.2 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFP05485.1 - 7.9e-06 24.8 0.0 0.024 13.4 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase Peptidase_S9 PF00326.16 KFP05485.1 - 9e-05 21.7 0.0 0.0003 20.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFP05485.1 - 0.00023 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFP05485.1 - 0.0072 15.7 0.1 0.45 9.9 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KFP05485.1 - 0.014 14.8 0.0 0.073 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative esterase DLH PF01738.13 KFP05485.1 - 0.02 14.1 0.0 0.065 12.4 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.7 KFP05485.1 - 0.052 12.0 0.0 0.62 8.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 KFP05485.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFP05485.1 - 0.081 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.6 KFP05485.1 - 0.086 12.5 0.0 0.39 10.3 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal S4 PF01479.20 KFP05486.1 - 5.8e-07 28.8 0.0 1.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ank_2 PF12796.2 KFP05487.1 - 5.2e-23 81.1 0.2 7.7e-19 67.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP05487.1 - 2.1e-15 56.7 1.1 4.4e-09 36.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP05487.1 - 3.4e-15 54.9 2.9 4.6e-08 32.4 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFP05487.1 - 5.9e-14 51.7 3.1 8.2e-06 25.8 0.2 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP05487.1 - 2e-13 49.1 0.8 8.5e-05 22.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat TAS2R PF05296.8 KFP05488.1 - 1.7e-58 197.8 37.9 2e-58 197.6 26.3 1.0 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) DUF4227 PF14004.1 KFP05488.1 - 2.1 8.2 5.8 1.3 8.9 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) TAS2R PF05296.8 KFP05489.1 - 2.6e-57 194.0 33.4 3e-57 193.8 23.1 1.0 1 0 0 1 1 1 1 Mammalian taste receptor protein (TAS2R) Myosin_head PF00063.16 KFP05490.1 - 1.6e-243 809.7 8.7 1.9e-243 809.5 6.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KFP05490.1 - 8.9e-06 24.9 6.3 0.0012 18.2 1.2 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KFP05490.1 - 0.0013 18.8 0.1 0.0078 16.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain Myosin_N PF02736.14 KFP05490.1 - 0.04 13.6 0.2 0.098 12.3 0.1 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Nop10p PF04135.7 KFP05490.1 - 0.051 13.3 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family AAA_10 PF12846.2 KFP05490.1 - 0.067 12.6 1.2 0.42 10.0 0.1 2.4 2 1 0 2 2 2 0 AAA-like domain T2SE PF00437.15 KFP05490.1 - 0.074 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 KFP05490.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KFP05490.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain EzrA PF06160.7 KFP05491.1 - 0.0013 17.0 12.8 0.0018 16.5 8.9 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Lectin_N PF03954.9 KFP05491.1 - 0.0022 17.4 2.8 0.005 16.2 1.9 1.6 1 1 0 1 1 1 1 Hepatic lectin, N-terminal domain DUF342 PF03961.8 KFP05491.1 - 0.0068 14.8 10.2 0.0075 14.7 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) AAA_13 PF13166.1 KFP05491.1 - 0.017 13.5 9.4 0.02 13.4 6.5 1.0 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.12 KFP05491.1 - 0.031 13.9 13.6 0.59 9.8 1.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF2408 PF10303.4 KFP05491.1 - 0.043 13.9 8.8 0.057 13.5 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Acetate_kinase PF00871.12 KFP05491.1 - 0.073 11.5 0.3 0.14 10.6 0.0 1.5 1 1 1 2 2 2 0 Acetokinase family TMF_DNA_bd PF12329.3 KFP05491.1 - 0.077 12.8 17.9 0.54 10.1 3.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 KFP05491.1 - 0.081 12.1 23.7 0.53 9.4 16.5 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KFP05491.1 - 0.094 11.7 19.9 0.14 11.2 13.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2492 PF10678.4 KFP05491.1 - 0.12 12.5 1.2 0.22 11.5 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2492) Baculo_p24 PF05073.7 KFP05491.1 - 0.14 11.6 3.5 0.19 11.3 2.5 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Sipho_Gp157 PF05565.6 KFP05491.1 - 0.16 11.5 11.8 0.19 11.2 7.7 1.4 1 1 0 1 1 1 0 Siphovirus Gp157 IZUMO PF15005.1 KFP05491.1 - 0.16 12.0 8.7 0.17 11.8 5.6 1.3 1 1 0 1 1 1 0 Izumo sperm-egg fusion TMF_TATA_bd PF12325.3 KFP05491.1 - 0.17 11.6 20.7 0.49 10.1 5.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Herpes_ICP4_N PF03584.10 KFP05491.1 - 0.24 10.8 1.6 0.36 10.3 1.1 1.2 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Uds1 PF15456.1 KFP05491.1 - 0.25 11.3 12.2 1.3 9.0 2.3 2.4 2 1 0 2 2 2 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 KFP05491.1 - 0.28 11.2 14.7 6.1 6.9 10.2 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RdRP_4 PF02123.11 KFP05491.1 - 0.29 9.8 5.0 0.34 9.5 3.5 1.0 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase FlaC_arch PF05377.6 KFP05491.1 - 0.29 11.0 9.2 4.9 7.1 0.8 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2508 PF10704.4 KFP05491.1 - 0.3 11.2 10.1 0.19 11.8 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF4407 PF14362.1 KFP05491.1 - 0.34 9.8 9.4 0.67 8.8 6.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GABP-alpha PF11620.3 KFP05491.1 - 0.36 10.8 7.4 4.3 7.4 0.5 2.3 1 1 1 2 2 2 0 GA-binding protein alpha chain bZIP_1 PF00170.16 KFP05491.1 - 0.38 10.7 18.1 0.99 9.4 5.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 KFP05491.1 - 0.39 10.2 25.1 49 3.4 17.4 2.1 1 1 0 1 1 1 0 IncA protein WHIM3 PF15614.1 KFP05491.1 - 0.43 10.3 2.1 1.1 9.1 1.5 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 YajC PF02699.10 KFP05491.1 - 0.43 10.2 0.0 0.43 10.2 0.0 2.6 3 1 0 3 3 2 0 Preprotein translocase subunit MRP-S27 PF10037.4 KFP05491.1 - 0.64 8.8 11.9 0.7 8.7 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF812 PF05667.6 KFP05491.1 - 0.84 8.0 13.9 1.2 7.5 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF148 PF02520.12 KFP05491.1 - 0.86 9.4 8.9 0.41 10.4 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 NPV_P10 PF05531.7 KFP05491.1 - 0.99 9.6 10.1 3.1 8.0 0.9 2.5 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein PilJ PF13675.1 KFP05491.1 - 1 9.6 7.3 2.5 8.4 5.1 1.7 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 KFP05491.1 - 1.1 9.1 7.0 8 6.2 4.1 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 KFP05491.1 - 1.2 9.1 7.2 0.93 9.5 1.2 2.6 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Vir_act_alpha_C PF10400.4 KFP05491.1 - 1.2 9.5 16.5 3.6 8.0 0.3 2.9 1 1 2 3 3 3 0 Virulence activator alpha C-term Striatin PF08232.7 KFP05491.1 - 1.4 9.2 18.5 4.2 7.6 3.6 2.1 1 1 1 2 2 2 0 Striatin family V_ATPase_I PF01496.14 KFP05491.1 - 1.5 6.5 14.1 2.6 5.8 9.8 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 KFP05491.1 - 1.9 8.6 11.9 1.9 8.6 7.6 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC155 PF14662.1 KFP05491.1 - 2.9 7.4 23.2 0.85 9.1 5.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF479 PF04336.7 KFP05491.1 - 3.8 7.6 9.0 3.7 7.7 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF479 Prefoldin_2 PF01920.15 KFP05491.1 - 4.2 7.1 22.3 1.6 8.5 1.9 2.7 3 0 0 3 3 2 0 Prefoldin subunit Phage_GPO PF05929.6 KFP05491.1 - 4.4 6.4 7.9 5.6 6.1 5.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CENP-F_leu_zip PF10473.4 KFP05491.1 - 4.6 7.0 25.4 18 5.1 17.6 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SEO_N PF14576.1 KFP05491.1 - 4.7 6.4 9.1 0.29 10.3 1.4 2.0 1 1 1 2 2 2 0 Sieve element occlusion N-terminus CENP-Q PF13094.1 KFP05491.1 - 5 7.1 25.7 6 6.8 6.0 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.10 KFP05491.1 - 5.2 6.1 10.5 6.4 5.8 7.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3763 PF12592.3 KFP05491.1 - 5.2 6.7 13.4 1.2 8.8 1.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3763) TBPIP PF07106.8 KFP05491.1 - 6.3 6.3 17.8 8.1 5.9 4.7 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IL6 PF00489.12 KFP05491.1 - 6.5 6.3 9.3 19 4.8 4.3 2.1 1 1 1 2 2 2 0 Interleukin-6/G-CSF/MGF family Syntaxin-6_N PF09177.6 KFP05491.1 - 6.5 7.2 12.1 7 7.1 1.5 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 KFP05491.1 - 6.9 6.4 19.6 24 4.6 13.6 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 KFP05491.1 - 7 6.3 19.0 4.4 7.0 4.0 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Peptidase_S46 PF10459.4 KFP05491.1 - 9.1 4.5 10.1 11 4.2 7.0 1.0 1 0 0 1 1 1 0 Peptidase S46 Ax_dynein_light PF10211.4 KFP05491.1 - 9.6 5.9 20.9 11 5.8 7.1 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain IQ PF00612.22 KFP05492.1 - 0.00016 21.0 0.4 0.00036 19.9 0.3 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ca_chan_IQ PF08763.6 KFP05492.1 - 0.21 10.8 2.2 0.35 10.1 1.5 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Brr6_like_C_C PF10104.4 KFP05493.1 - 0.3 10.5 1.0 1.2 8.7 0.7 1.9 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain YjfB_motility PF14070.1 KFP05493.1 - 0.49 10.2 3.4 1.6 8.5 2.4 1.9 1 0 0 1 1 1 0 Putative motility protein WW PF00397.21 KFP05494.1 - 2e-09 37.1 0.1 2.9e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 WW domain Asp PF00026.18 KFP05495.1 - 8.9e-36 123.7 0.0 1.4e-35 123.1 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KFP05495.1 - 3.9e-11 42.7 0.0 5.7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal zf-RING_2 PF13639.1 KFP05496.1 - 2.7e-07 30.2 8.3 4.8e-07 29.4 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP05496.1 - 0.00038 20.4 8.9 0.00081 19.4 6.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFP05496.1 - 0.0043 17.0 5.7 0.009 16.0 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP05496.1 - 0.023 14.3 11.2 0.045 13.4 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KFP05496.1 - 0.049 13.6 9.6 0.091 12.8 6.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_5 PF14634.1 KFP05496.1 - 0.055 13.2 8.8 0.13 12.0 6.1 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 KFP05496.1 - 0.26 11.1 6.7 0.65 9.8 4.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 KFP05496.1 - 0.67 10.0 6.0 1.2 9.1 4.2 1.4 1 0 0 1 1 1 0 RING-like domain Baculo_PEP_C PF04513.7 KFP05496.1 - 8.9 6.1 12.6 22 4.8 0.1 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S8 PF00082.17 KFP05497.1 - 3.9e-46 157.4 1.1 1.4e-45 155.6 0.7 1.8 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFP05497.1 - 2.6e-26 91.1 0.0 6.1e-26 90.0 0.0 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain CH PF00307.26 KFP05498.1 - 1.2e-11 44.5 0.0 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.13 KFP05498.1 - 4e-10 38.8 4.2 4.6e-09 35.4 1.4 2.5 2 0 0 2 2 2 2 Calponin family repeat SID-1_RNA_chan PF13965.1 KFP05499.1 - 4.1e-170 566.7 32.3 5e-138 460.7 16.7 2.9 2 1 0 2 2 2 2 dsRNA-gated channel SID-1 MARVEL PF01284.18 KFP05499.1 - 1.3 8.8 14.4 0.028 14.2 1.2 3.0 3 0 0 3 3 3 0 Membrane-associating domain Lipase_GDSL_2 PF13472.1 KFP05500.1 - 7.4e-07 29.4 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.20 KFP05501.1 - 1.5e-68 230.8 0.0 3.2e-68 229.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05501.1 - 3.1e-35 121.4 1.8 5.3e-35 120.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP05501.1 - 9.1e-07 28.1 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP05501.1 - 0.01 14.9 0.3 0.025 13.6 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apolipoprotein PF01442.13 KFP05502.1 - 3.2e-55 186.7 19.3 3.2e-55 186.7 13.4 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 KFP05502.1 - 5.3e-08 33.1 10.6 0.015 15.6 0.9 5.0 1 1 4 5 5 5 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KFP05502.1 - 7.3e-06 26.2 11.9 81 3.6 8.2 5.1 1 1 0 1 1 1 0 YtxH-like protein Baculo_PEP_C PF04513.7 KFP05502.1 - 2.6e-05 24.0 6.3 0.065 13.0 0.2 3.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 KFP05502.1 - 0.0011 18.4 7.4 0.39 10.0 0.2 3.3 1 1 3 4 4 4 2 Bacillus haemolytic enterotoxin (HBL) KMP11 PF03037.11 KFP05502.1 - 0.0029 18.1 3.1 1.1 9.8 0.2 3.3 1 1 2 3 3 3 1 Kinetoplastid membrane protein 11 Exo70 PF03081.10 KFP05502.1 - 0.004 15.9 1.0 0.034 12.9 0.1 2.0 1 1 1 2 2 2 1 Exo70 exocyst complex subunit Dynamin_M PF01031.15 KFP05502.1 - 0.0049 15.6 1.5 0.0099 14.6 0.8 1.5 1 1 0 1 1 1 1 Dynamin central region DUF948 PF06103.6 KFP05502.1 - 0.0054 16.5 4.6 0.14 12.0 0.1 3.7 1 1 4 5 5 5 1 Bacterial protein of unknown function (DUF948) 4HB_MCP_1 PF12729.2 KFP05502.1 - 0.0069 15.7 8.9 0.015 14.6 2.9 2.3 1 1 1 2 2 2 1 Four helix bundle sensory module for signal transduction ApoC-I PF04691.7 KFP05502.1 - 0.013 15.1 8.6 1.3 8.7 0.1 4.5 3 1 3 6 6 5 0 Apolipoprotein C-I (ApoC-1) Exonuc_VII_L PF02601.10 KFP05502.1 - 0.015 14.5 8.2 0.06 12.5 5.5 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF2959 PF11172.3 KFP05502.1 - 0.018 14.8 10.8 0.044 13.5 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Spectrin PF00435.16 KFP05502.1 - 0.019 15.2 11.1 0.55 10.5 4.2 2.4 2 0 0 2 2 2 0 Spectrin repeat NIT PF08376.5 KFP05502.1 - 0.022 14.3 4.9 0.33 10.4 0.5 2.4 2 0 0 2 2 2 0 Nitrate and nitrite sensing DUF2317 PF10079.4 KFP05502.1 - 0.022 13.4 13.9 0.055 12.0 2.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Arc_PepC PF06819.6 KFP05502.1 - 0.022 14.6 0.2 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Phe_tRNA-synt_N PF02912.13 KFP05502.1 - 0.027 14.1 5.7 0.22 11.2 0.3 3.6 3 1 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Prominin PF05478.6 KFP05502.1 - 0.027 12.0 4.0 0.13 9.8 0.2 2.1 1 1 1 2 2 2 0 Prominin ApoA-II PF04711.8 KFP05502.1 - 0.039 13.8 6.3 4.7 7.1 0.1 3.8 2 2 0 3 3 3 0 Apolipoprotein A-II (ApoA-II) ApoLp-III PF07464.6 KFP05502.1 - 0.046 13.7 11.9 0.42 10.6 3.2 3.0 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF4015 PF13200.1 KFP05502.1 - 0.052 12.4 0.3 0.53 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase domain ApoO PF09769.4 KFP05502.1 - 0.056 13.1 2.1 0.79 9.4 0.3 2.8 2 1 1 3 3 3 0 Apolipoprotein O AAA_13 PF13166.1 KFP05502.1 - 0.076 11.4 8.4 0.19 10.1 5.3 1.7 1 1 0 1 1 1 0 AAA domain KapB PF08810.5 KFP05502.1 - 0.078 13.0 6.9 0.46 10.5 0.9 3.3 1 1 3 4 4 4 0 Kinase associated protein B DUF1732 PF08340.6 KFP05502.1 - 0.08 12.7 2.1 1.2 9.0 0.4 2.9 3 1 0 3 3 2 0 Domain of unknown function (DUF1732) Fib_alpha PF08702.5 KFP05502.1 - 0.087 12.9 6.1 0.2 11.7 1.2 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Hemerythrin PF01814.18 KFP05502.1 - 0.1 12.7 5.9 0.55 10.3 1.9 2.6 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain VirE PF05272.6 KFP05502.1 - 0.12 11.8 2.8 0.57 9.6 0.2 2.2 1 1 1 2 2 2 0 Virulence-associated protein E AAR2 PF05282.6 KFP05502.1 - 0.13 11.2 5.4 0.78 8.6 0.5 2.5 1 1 2 3 3 3 0 AAR2 protein COG2 PF06148.6 KFP05502.1 - 0.16 11.8 10.2 9 6.1 0.2 4.3 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3829 PF12889.2 KFP05502.1 - 0.18 11.0 8.5 0.77 8.8 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) OmpH PF03938.9 KFP05502.1 - 0.19 11.6 13.1 6.6 6.6 9.0 2.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Acyl-CoA_dh_C PF12806.2 KFP05502.1 - 0.2 11.5 1.9 2.6 7.9 0.0 3.3 1 1 5 6 6 5 0 Acetyl-CoA dehydrogenase C-terminal like DUF2458 PF10454.4 KFP05502.1 - 0.27 11.1 11.9 0.98 9.2 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) LMP PF04778.7 KFP05502.1 - 0.3 10.8 5.1 0.3 10.8 0.4 2.3 1 1 2 3 3 3 0 LMP repeated region NPV_P10 PF05531.7 KFP05502.1 - 0.39 10.9 8.1 1.5 9.0 1.4 3.8 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IZUMO PF15005.1 KFP05502.1 - 0.4 10.7 6.6 0.29 11.1 2.0 2.1 1 1 1 2 2 2 0 Izumo sperm-egg fusion Vac_Fusion PF02346.11 KFP05502.1 - 0.49 9.8 4.0 6.9 6.1 0.7 3.5 2 2 0 2 2 2 0 Chordopoxvirus fusion protein Phasin PF05597.6 KFP05502.1 - 0.49 10.1 11.1 1.3 8.7 2.0 3.0 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) His_Phos_1 PF00300.17 KFP05502.1 - 0.57 10.2 4.2 1.4 8.9 0.3 2.7 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 1) Swi5 PF07061.6 KFP05502.1 - 0.75 9.6 5.8 5 6.9 0.0 3.4 2 2 1 3 3 3 0 Swi5 Atg14 PF10186.4 KFP05502.1 - 0.79 8.6 13.7 0.34 9.8 6.2 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 KFP05502.1 - 0.8 9.2 15.4 0.53 9.8 5.0 2.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SBP_bac_7 PF03480.8 KFP05502.1 - 0.86 8.6 7.5 1.5 7.8 0.3 2.7 1 1 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Peptidase_S46 PF10459.4 KFP05502.1 - 0.88 7.9 5.8 0.96 7.7 4.0 1.2 1 0 0 1 1 1 0 Peptidase S46 CpXC PF14353.1 KFP05502.1 - 0.92 9.4 3.5 4.4 7.2 0.4 2.8 1 1 1 2 2 2 0 CpXC protein CDC37_N PF03234.9 KFP05502.1 - 1.6 9.0 9.6 1.1 9.5 3.7 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding FlgN PF05130.7 KFP05502.1 - 1.9 8.7 18.0 7.9 6.7 4.6 3.5 1 1 2 3 3 3 0 FlgN protein Snapin_Pallidin PF14712.1 KFP05502.1 - 2 8.7 10.9 17 5.8 4.0 3.3 1 1 2 3 3 2 0 Snapin/Pallidin DUF342 PF03961.8 KFP05502.1 - 2.1 6.6 9.5 1.4 7.2 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FUSC PF04632.7 KFP05502.1 - 2.2 6.5 6.9 9.8 4.4 2.8 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1451 PF07295.6 KFP05502.1 - 4.6 7.0 11.4 2 8.1 2.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1451) DUF733 PF05306.6 KFP05502.1 - 5.2 7.4 11.5 5.5 7.3 4.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF733) Med9 PF07544.8 KFP05502.1 - 5.4 6.8 9.8 2.4 7.9 2.1 3.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Flg_hook PF02120.11 KFP05502.1 - 5.6 6.7 7.7 6.3 6.5 1.6 3.6 2 1 1 3 3 2 0 Flagellar hook-length control protein FliK IncA PF04156.9 KFP05502.1 - 5.8 6.4 21.6 56 3.2 0.2 2.7 1 1 1 2 2 2 0 IncA protein ACCA PF03255.9 KFP05502.1 - 6.2 6.3 8.4 6.1 6.3 2.2 3.0 1 1 3 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit zf-ZPR1 PF03367.8 KFP05504.1 - 1.4e-102 339.6 0.2 1.4e-51 173.8 0.0 2.0 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Elf1 PF05129.8 KFP05504.1 - 0.039 13.6 1.9 0.3 10.8 0.3 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.7 KFP05504.1 - 0.062 13.0 1.2 0.11 12.2 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.5 KFP05504.1 - 0.23 11.4 4.8 34 4.4 0.0 3.5 3 0 0 3 3 3 0 Zinc ribbon domain UPF0547 PF10571.4 KFP05504.1 - 0.39 10.4 5.5 4.5 7.0 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DZR PF12773.2 KFP05504.1 - 0.99 9.2 4.7 2.1 8.2 1.6 2.5 2 1 0 2 2 2 0 Double zinc ribbon I-set PF07679.11 KFP05505.1 - 1.2e-25 89.1 0.1 2.5e-11 43.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05505.1 - 2.1e-25 88.6 1.4 4.6e-11 42.6 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP05505.1 - 6.6e-20 71.1 3.0 1.1e-07 31.7 0.1 4.4 3 1 0 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP05505.1 - 5.9e-18 65.1 10.9 9.8e-10 38.7 0.0 3.8 4 0 0 4 4 3 3 Immunoglobulin domain ig PF00047.20 KFP05505.1 - 1.3e-16 60.4 4.2 1.8e-05 24.7 0.0 4.0 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.7 KFP05505.1 - 1.6e-12 47.1 3.4 6.4e-11 41.9 0.0 3.3 4 0 0 4 4 3 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP05505.1 - 0.00045 18.6 0.6 0.22 9.7 0.1 3.0 2 1 1 3 3 3 1 Alphaherpesvirus glycoprotein E C2-set PF05790.10 KFP05505.1 - 0.014 15.3 0.1 24 4.9 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain OppC_N PF12911.2 KFP05505.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Syndecan PF01034.15 KFP05505.1 - 0.044 13.4 0.1 0.26 10.9 0.1 2.0 2 0 0 2 2 2 0 Syndecan domain DUF3439 PF11921.3 KFP05505.1 - 0.4 10.4 9.4 0.87 9.3 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rubella_E2 PF05749.6 KFP05505.1 - 0.7 9.0 4.1 0.86 8.7 2.3 1.5 1 1 0 1 1 1 0 Rubella membrane glycoprotein E2 RNase_T PF00929.19 KFP05506.1 - 1.4e-23 84.0 0.0 1.7e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.17 KFP05507.1 - 2.8e-09 36.4 0.0 4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05507.1 - 6.3e-07 29.2 0.0 9.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP05507.1 - 7.1e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.1 KFP05508.1 - 1.3e-37 126.2 50.4 5.8e-07 29.4 0.9 9.6 10 0 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFP05508.1 - 1.5e-28 97.3 61.2 0.00019 21.6 1.7 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type BTB PF00651.26 KFP05508.1 - 1.2e-25 89.6 2.8 2.3e-25 88.7 1.9 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KFP05508.1 - 1.5e-25 87.6 55.7 8.5e-05 22.6 1.7 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP05508.1 - 2e-19 68.7 43.4 3.6e-05 23.4 0.1 9.5 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP05508.1 - 1.9e-18 66.0 36.4 8.4e-05 22.5 0.1 9.6 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP05508.1 - 6.9e-15 54.6 44.7 0.00039 20.5 0.4 9.5 9 0 0 9 9 9 5 Zinc-finger of C2H2 type Endonuclease_7 PF02945.10 KFP05508.1 - 0.011 15.4 1.3 0.011 15.4 0.9 3.9 2 2 2 4 4 4 0 Recombination endonuclease VII zf-C2H2_2 PF12756.2 KFP05508.1 - 0.021 14.9 42.6 0.17 12.0 0.3 8.2 1 1 6 7 7 7 0 C2H2 type zinc-finger (2 copies) DZR PF12773.2 KFP05508.1 - 0.031 14.0 24.5 1.1 9.0 3.9 5.1 2 2 0 2 2 2 0 Double zinc ribbon GATA PF00320.22 KFP05508.1 - 0.45 9.8 11.2 7.4 6.0 0.2 4.8 4 0 0 4 4 4 0 GATA zinc finger Neur_chan_LBD PF02931.18 KFP05509.1 - 1.2e-53 181.5 4.1 1.5e-53 181.1 2.9 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP05509.1 - 4.2e-26 92.2 0.0 5.7e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region UCH PF00443.24 KFP05510.1 - 1e-49 169.1 0.5 1e-49 169.1 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP05510.1 - 1.9e-15 57.1 1.7 1.9e-15 57.1 1.2 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PMP22_Claudin PF00822.15 KFP05511.1 - 1.8e-14 53.7 0.3 2e-14 53.5 0.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP05511.1 - 2.1e-05 24.2 0.4 3.6e-05 23.5 0.3 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction IRK PF01007.15 KFP05512.1 - 5.3e-143 475.8 0.4 6e-143 475.7 0.3 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KFP05512.1 - 0.034 13.8 4.4 0.094 12.4 3.0 1.9 1 1 0 1 1 1 0 Ion channel Ion_trans PF00520.26 KFP05512.1 - 0.056 12.6 3.4 0.081 12.1 2.4 1.2 1 0 0 1 1 1 0 Ion transport protein Ufd2P_core PF10408.4 KFP05513.1 - 4.2e-183 610.0 9.8 5.9e-183 609.5 6.8 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KFP05513.1 - 1.7e-32 111.2 0.6 5.6e-32 109.5 0.4 2.0 1 0 0 1 1 1 1 U-box domain ATP-synt_G PF04718.10 KFP05514.1 - 9.9e-28 96.8 0.0 1.2e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit SET PF00856.23 KFP05515.1 - 1.9e-23 83.5 0.7 1.9e-23 83.5 0.5 5.4 5 1 0 5 5 5 1 SET domain FYRC PF05965.9 KFP05515.1 - 3.2e-23 81.3 0.0 9.4e-23 79.8 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 KFP05515.1 - 2.3e-16 58.9 0.2 4.9e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.1 KFP05515.1 - 1e-14 54.4 11.0 1e-14 54.4 7.6 5.7 4 1 1 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.24 KFP05515.1 - 3.2e-14 52.3 53.6 3.3e-08 33.0 8.4 5.7 5 1 2 7 7 7 3 PHD-finger zf-CXXC PF02008.15 KFP05515.1 - 2.1e-13 49.8 24.3 2.1e-13 49.8 16.9 5.4 5 0 0 5 5 5 1 CXXC zinc finger domain zf-HC5HC2H_2 PF13832.1 KFP05515.1 - 1.7e-08 34.3 9.9 1.7e-08 34.3 6.9 5.1 4 1 1 5 5 5 1 PHD-zinc-finger like domain PHD_2 PF13831.1 KFP05515.1 - 1.2e-05 24.4 25.8 0.0014 17.8 2.0 4.2 3 0 0 3 3 3 2 PHD-finger TPR_2 PF07719.12 KFP05516.1 - 0.00088 19.0 0.2 0.16 11.9 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFP05516.1 - 0.0021 17.6 0.1 0.0049 16.4 0.0 1.6 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 KFP05516.1 - 0.13 11.8 0.0 9.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Adap_comp_sub PF00928.16 KFP05518.1 - 8.2e-38 129.9 0.3 1.3e-37 129.3 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFP05518.1 - 4.7e-06 26.3 0.3 8.6e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.11 KFP05519.1 - 9.4e-39 133.1 31.3 1.4e-38 132.5 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP05519.1 - 1.6 7.2 38.0 0.055 12.0 8.0 3.7 2 2 1 3 3 3 0 Sugar (and other) transporter Cytochrome-c551 PF10643.4 KFP05519.1 - 8.3 5.6 7.3 16 4.6 1.0 2.3 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Sybindin PF04099.7 KFP05520.1 - 3.5e-50 169.4 0.0 3.8e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KFP05520.1 - 7.8e-09 35.4 0.0 9.6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_S25 PF03297.10 KFP05521.1 - 8.8e-47 157.4 5.6 1.1e-46 157.2 3.9 1.1 1 0 0 1 1 1 1 S25 ribosomal protein MRVI1 PF05781.7 KFP05521.1 - 0.0082 14.5 0.1 0.0096 14.3 0.1 1.1 1 0 0 1 1 1 1 MRVI1 protein TrmB PF01978.14 KFP05521.1 - 0.026 14.1 0.2 0.1 12.3 0.1 1.8 1 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB CCDC84 PF14968.1 KFP05522.1 - 1.3e-42 146.5 5.8 1.4e-42 146.4 4.0 1.0 1 0 0 1 1 1 1 Coiled coil protein 84 Fork_head PF00250.13 KFP05523.1 - 1.1e-22 79.8 0.0 1.3e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Fork head domain DUF3872 PF12988.2 KFP05523.1 - 0.037 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) DEAD PF00270.24 KFP05525.1 - 4.3e-39 133.7 2.5 4.7e-39 133.5 0.3 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP05525.1 - 3.6e-25 87.6 0.1 8.3e-25 86.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KFP05525.1 - 0.00062 18.9 0.1 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.18 KFP05525.1 - 0.014 14.2 0.1 0.016 13.9 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain VPS11_C PF12451.3 KFP05526.1 - 1.8e-19 69.2 0.2 7.3e-19 67.3 0.1 2.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 KFP05526.1 - 2.2e-16 59.7 14.5 6.4e-15 55.0 2.7 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KFP05526.1 - 2.3e-07 30.5 9.0 7.2e-07 28.9 6.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP05526.1 - 9.3e-07 28.7 7.5 2.1e-06 27.6 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP05526.1 - 8e-06 25.8 2.8 2.1e-05 24.5 1.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP05526.1 - 0.00012 21.6 8.0 0.00027 20.5 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP05526.1 - 0.0012 18.4 5.8 0.0025 17.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP05526.1 - 0.0018 17.9 8.6 0.0046 16.6 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 KFP05526.1 - 0.013 15.0 1.7 0.055 13.1 0.0 2.8 3 0 0 3 3 3 0 TPR repeat zf-C3HC4_4 PF15227.1 KFP05526.1 - 0.019 14.8 8.2 0.057 13.3 5.7 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DivIC PF04977.10 KFP05526.1 - 0.025 14.0 4.1 0.074 12.5 2.8 1.8 1 0 0 1 1 1 0 Septum formation initiator zf-Apc11 PF12861.2 KFP05526.1 - 0.031 14.0 1.8 0.11 12.3 1.3 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger BTB_2 PF02214.17 KFP05526.1 - 0.1 12.8 1.5 0.23 11.6 0.2 2.3 2 0 0 2 2 1 0 BTB/POZ domain zf-RING_6 PF14835.1 KFP05526.1 - 0.17 11.6 1.2 0.4 10.5 0.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KFP05526.1 - 0.88 9.1 5.2 2.5 7.6 3.6 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prefoldin_2 PF01920.15 KFP05526.1 - 1.9 8.3 12.2 6.3 6.6 3.2 3.7 3 0 0 3 3 3 0 Prefoldin subunit zf-RING-like PF08746.6 KFP05526.1 - 4.3 7.4 6.5 12 5.9 4.5 1.8 1 0 0 1 1 1 0 RING-like domain Porphobil_deam PF01379.15 KFP05527.1 - 4.1e-86 287.3 0.0 5.5e-86 286.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KFP05527.1 - 1.4e-19 69.9 0.1 2.4e-18 66.0 0.1 2.4 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CUE PF02845.11 KFP05527.1 - 0.0026 17.2 0.2 0.32 10.5 0.0 2.8 3 0 0 3 3 3 1 CUE domain CagA PF03507.8 KFP05527.1 - 0.021 14.6 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 CagA exotoxin MGS PF02142.17 KFP05527.1 - 0.03 14.2 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 MGS-like domain Nuf2 PF03800.9 KFP05529.1 - 8.6e-42 142.5 6.0 1.2e-41 142.1 0.1 2.6 2 0 0 2 2 2 1 Nuf2 family Prominin PF05478.6 KFP05529.1 - 0.00097 16.8 5.4 0.00097 16.8 3.7 2.1 2 0 0 2 2 2 1 Prominin Filament PF00038.16 KFP05529.1 - 0.1 12.0 47.2 0.073 12.5 10.0 4.0 1 1 1 3 3 3 0 Intermediate filament protein G-gamma PF00631.17 KFP05529.1 - 0.26 11.0 4.4 0.58 9.9 0.1 2.9 2 0 0 2 2 2 0 GGL domain ATG16 PF08614.6 KFP05529.1 - 1.2 8.8 42.1 0.036 13.8 15.4 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KFP05529.1 - 1.9 7.5 7.6 2.6 7.1 1.9 2.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein COG5 PF10392.4 KFP05529.1 - 2.1 8.3 27.7 0.024 14.5 7.4 4.1 2 1 2 5 5 5 0 Golgi transport complex subunit 5 Met_10 PF02475.11 KFP05529.1 - 6.2 6.3 11.7 0.31 10.5 0.8 3.2 3 1 1 4 4 4 0 Met-10+ like-protein ATP-synt_F6 PF05511.6 KFP05529.1 - 8.4 6.3 13.2 0.049 13.5 1.2 3.0 2 2 0 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 MAPEG PF01124.13 KFP05530.1 - 3.9e-24 84.7 1.2 4.4e-24 84.5 0.9 1.0 1 0 0 1 1 1 1 MAPEG family DmsC PF04976.7 KFP05530.1 - 0.041 13.1 0.2 0.071 12.3 0.1 1.4 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) Aldedh PF00171.17 KFP05531.1 - 1.5e-174 580.7 0.0 1.7e-174 580.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF106 PF01956.11 KFP05532.1 - 9e-42 142.4 0.8 1e-41 142.2 0.5 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 ATG19_autophagy PF12744.2 KFP05532.1 - 0.0016 17.7 1.3 0.002 17.4 0.9 1.1 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding Exonuc_VII_L PF02601.10 KFP05532.1 - 0.0092 15.2 0.1 0.0092 15.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit OmpH PF03938.9 KFP05532.1 - 0.024 14.5 3.7 0.034 14.0 2.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 KFP05532.1 - 0.025 14.4 0.7 0.038 13.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TRAM1 PF08390.6 KFP05532.1 - 0.029 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 TRAM1-like protein TMPIT PF07851.8 KFP05532.1 - 0.29 10.1 2.9 2.8 6.9 0.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF1090 PF06476.7 KFP05532.1 - 0.71 9.5 12.6 1.1 8.9 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DivIC PF04977.10 KFP05532.1 - 0.8 9.2 11.5 0.43 10.0 1.8 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF3671 PF12420.3 KFP05532.1 - 1.3 8.9 5.7 0.13 12.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function Bap31 PF05529.7 KFP05532.1 - 1.7 8.0 8.6 0.56 9.6 4.3 1.4 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF3435 PF11917.3 KFP05532.1 - 3.2 6.3 6.4 4.3 5.9 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF874 PF05917.6 KFP05532.1 - 5 5.8 11.1 6.6 5.4 7.7 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Atg14 PF10186.4 KFP05532.1 - 6 5.7 7.4 8.4 5.2 5.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PBP_sp32 PF07222.7 KFP05532.1 - 8.5 5.4 7.0 12 5.0 4.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PRK PF00485.13 KFP05533.1 - 3.1e-46 157.4 0.7 3.5e-46 157.2 0.5 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KFP05533.1 - 0.13 12.5 0.5 0.36 11.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain Kelch_1 PF01344.20 KFP05534.1 - 1.3e-90 296.7 14.2 5e-17 61.1 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFP05534.1 - 1.1e-56 186.7 7.1 2.9e-10 39.8 0.0 6.3 1 1 5 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KFP05534.1 - 8.4e-41 137.5 7.0 6.3e-08 32.2 0.0 6.3 3 1 3 6 6 6 6 Galactose oxidase, central domain BACK PF07707.10 KFP05534.1 - 6.7e-38 128.6 0.3 1.3e-37 127.7 0.0 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_3 PF13415.1 KFP05534.1 - 6e-37 124.9 15.6 6.1e-06 26.2 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFP05534.1 - 1.1e-33 115.4 0.3 2.6e-33 114.3 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 KFP05534.1 - 1.7e-31 106.7 7.0 1e-06 28.2 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 KFP05534.1 - 5.1e-09 35.8 13.3 0.11 12.4 0.0 6.2 7 0 0 7 7 7 4 Kelch motif Varsurf_PPLC PF03490.8 KFP05534.1 - 0.093 12.4 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C PQQ_3 PF13570.1 KFP05534.1 - 4.2 7.7 14.3 1.2 9.5 0.4 4.4 4 0 0 4 4 4 0 PQQ-like domain CENP-L PF13092.1 KFP05535.1 - 2.3e-35 121.7 0.0 3e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 tRNA-synt_2 PF00152.15 KFP05536.1 - 2.5e-111 371.7 0.0 3.2e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.9 KFP05536.1 - 6.9e-13 48.5 0.0 2.4e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 GAD domain tRNA_anti-codon PF01336.20 KFP05536.1 - 1.5e-08 34.4 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KFP05536.1 - 0.019 14.5 2.8 0.34 10.4 0.1 2.7 2 1 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) RGS PF00615.14 KFP05537.1 - 2.7e-38 130.6 2.1 3.5e-38 130.3 1.5 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 KFP05538.1 - 2e-37 127.8 4.1 2.5e-37 127.5 2.8 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.14 KFP05540.1 - 9e-09 35.4 0.0 0.0023 18.0 0.0 3.5 4 0 0 4 4 4 2 Regulator of G protein signaling domain Gln-synt_C PF00120.19 KFP05541.1 - 3.5e-66 222.9 0.0 4.4e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KFP05541.1 - 2.8e-21 74.8 0.0 4.7e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain AhpC-TSA PF00578.16 KFP05542.1 - 1.1e-14 54.1 0.0 1.2e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFP05542.1 - 2.3e-05 23.9 0.0 2.4e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin Syntaxin-6_N PF09177.6 KFP05543.1 - 1.1e-24 86.6 0.5 1.1e-24 86.6 0.3 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KFP05543.1 - 1.2e-15 56.9 3.4 1.2e-15 56.9 2.3 2.1 2 1 0 2 2 2 1 SNARE domain DUF3753 PF12575.3 KFP05543.1 - 0.05 13.4 2.6 0.15 11.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) UPF0184 PF03670.8 KFP05543.1 - 0.06 13.5 0.4 0.6 10.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Fusion_gly PF00523.13 KFP05543.1 - 0.07 11.1 0.2 0.12 10.3 0.1 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 FliD_C PF07195.7 KFP05543.1 - 0.11 11.8 3.6 3.1 7.0 0.0 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Syntaxin PF00804.20 KFP05543.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.7 1 1 1 2 2 2 0 Syntaxin Rifin_STEVOR PF02009.11 KFP05543.1 - 0.14 11.7 0.8 0.19 11.3 0.5 1.3 1 1 0 1 1 1 0 Rifin/stevor family TBPIP PF07106.8 KFP05543.1 - 0.22 11.0 8.6 0.064 12.8 0.4 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GP41 PF00517.12 KFP05543.1 - 0.43 10.0 8.7 1.3 8.5 0.3 2.5 1 1 1 2 2 2 0 Retroviral envelope protein DUF4492 PF14899.1 KFP05543.1 - 0.53 9.8 3.3 1.5 8.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Cortex-I_coil PF09304.5 KFP05543.1 - 2.2 8.3 8.7 7.9 6.5 0.3 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil Activator-TraM PF11657.3 KFP05543.1 - 9.8 5.6 10.3 11 5.5 0.0 3.0 2 1 1 3 3 3 0 Transcriptional activator TraM EXS PF03124.9 KFP05544.1 - 2.1e-116 388.7 22.8 3.2e-116 388.1 15.8 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KFP05544.1 - 2.1e-22 80.1 15.8 4e-22 79.3 7.6 2.5 2 1 0 2 2 2 1 SPX domain DUF1154 PF06631.6 KFP05544.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Ank_4 PF13637.1 KFP05545.1 - 2.5e-21 75.6 1.2 5.6e-14 52.2 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFP05545.1 - 5.6e-21 74.6 0.1 9e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP05545.1 - 2.3e-20 71.2 0.3 4.2e-09 35.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFP05545.1 - 8.5e-19 67.1 0.2 1.2e-11 44.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP05545.1 - 1.5e-14 52.6 0.4 5.5e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat ACBP PF00887.14 KFP05545.1 - 3.4e-14 52.2 0.2 5.9e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein GBP_repeat PF02526.9 KFP05545.1 - 0.1 12.0 0.0 4.2 6.8 0.0 2.9 3 0 0 3 3 3 0 Glycophorin-binding protein NeuB PF03102.9 KFP05545.1 - 0.11 11.6 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NeuB family LIM PF00412.17 KFP05546.1 - 1.8e-32 111.1 19.6 1.1e-16 60.5 2.1 2.2 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFP05546.1 - 2.1e-21 75.2 2.4 3.5e-21 74.5 1.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP05546.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain PSP1 PF04468.7 KFP05546.1 - 0.071 13.1 0.1 0.26 11.2 0.1 2.0 1 1 0 1 1 1 0 PSP1 C-terminal conserved region Orbi_VP3 PF01700.11 KFP05546.1 - 0.13 9.6 0.0 0.18 9.2 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein PHF5 PF03660.9 KFP05546.1 - 0.52 10.3 9.8 0.037 14.0 2.0 2.2 1 1 1 2 2 2 0 PHF5-like protein zf-RING_5 PF14634.1 KFP05546.1 - 4.8 6.9 0.0 4.8 6.9 0.0 3.6 2 1 0 2 2 2 0 zinc-RING finger domain DUF164 PF02591.10 KFP05546.1 - 8 6.3 10.0 9.9 6.0 1.1 2.8 2 0 0 2 2 2 0 Putative zinc ribbon domain Evr1_Alr PF04777.8 KFP05547.1 - 5.5e-26 90.2 0.1 3.9e-25 87.5 0.0 2.2 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.15 KFP05547.1 - 2.7e-05 23.7 0.0 0.00073 19.1 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 KFP05547.1 - 0.0043 17.2 0.0 8.3 6.6 0.0 3.5 3 0 0 3 3 3 1 Thioredoxin-like domain DUF3330 PF11809.3 KFP05547.1 - 0.038 13.8 0.2 1.7 8.5 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3330) HyaE PF07449.6 KFP05547.1 - 0.053 13.4 0.0 2.7 7.9 0.0 2.7 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Zn-ribbon_8 PF09723.5 KFP05547.1 - 0.16 11.9 3.0 8.7 6.3 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain CAP_GLY PF01302.20 KFP05548.1 - 7.9e-22 76.7 0.1 1.4e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LAP1C PF05609.7 KFP05549.1 - 8.1e-95 318.2 0.1 8.9e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) LAP1C PF05609.7 KFP05550.1 - 2.1e-86 290.4 0.0 2.4e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) F5_F8_type_C PF00754.20 KFP05551.1 - 2e-26 92.3 0.5 2e-26 92.3 0.3 1.9 2 0 0 2 2 2 1 F5/8 type C domain CUB PF00431.15 KFP05551.1 - 7e-25 87.2 0.0 1.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 CUB domain LCCL PF03815.14 KFP05551.1 - 1.3e-17 63.5 0.5 2.6e-17 62.5 0.1 1.7 2 0 0 2 2 2 1 LCCL domain Syndecan PF01034.15 KFP05551.1 - 0.065 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Sex_peptide PF08138.6 KFP05551.1 - 0.13 12.0 0.7 0.34 10.7 0.1 2.0 2 0 0 2 2 2 0 Sex peptide (SP) family CDC50 PF03381.10 KFP05552.1 - 1.8e-86 289.7 3.3 2.6e-86 289.2 2.3 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CMS1 PF14617.1 KFP05553.1 - 3.9e-28 98.2 3.1 1.6e-27 96.2 2.1 1.7 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KFP05553.1 - 2.4e-05 23.8 0.0 3.7e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase efThoc1 PF11957.3 KFP05553.1 - 0.011 14.2 2.9 0.14 10.6 0.0 2.0 1 1 1 2 2 2 0 THO complex subunit 1 transcription elongation factor DUF3408 PF11888.3 KFP05553.1 - 0.036 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Herpes_ori_bp PF02399.10 KFP05553.1 - 0.063 11.2 0.2 0.067 11.1 0.2 1.0 1 0 0 1 1 1 0 Origin of replication binding protein CortBP2 PF09727.4 KFP05554.1 - 8.1e-76 253.8 28.0 8.1e-76 253.8 19.4 6.8 2 2 4 6 6 6 2 Cortactin-binding protein-2 RabGAP-TBC PF00566.13 KFP05555.1 - 5.7e-21 74.9 2.2 9.4e-21 74.2 1.5 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 KFP05555.1 - 1.7e-07 31.5 0.0 9.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain eIF3_N PF09440.5 KFP05555.1 - 0.067 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain CN_hydrolase PF00795.17 KFP05556.1 - 1.9e-34 118.6 0.0 2.6e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPR_11 PF13414.1 KFP05557.1 - 3.1e-51 170.8 26.3 2.3e-20 72.0 0.9 6.7 5 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFP05557.1 - 8.1e-37 123.3 23.1 3.9e-07 29.4 0.1 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFP05557.1 - 8.4e-32 106.5 24.6 2.2e-05 24.0 0.0 10.7 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 KFP05557.1 - 2.3e-21 74.3 8.9 0.0024 18.3 0.0 8.4 5 2 4 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFP05557.1 - 7e-20 69.2 16.1 0.0087 15.7 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFP05557.1 - 7.6e-19 67.4 18.0 1.1e-05 25.3 0.2 6.8 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFP05557.1 - 3.7e-16 59.3 8.5 0.0064 17.1 0.0 6.8 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFP05557.1 - 1.9e-15 55.6 14.4 0.007 16.4 0.0 9.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP05557.1 - 2.4e-12 46.9 15.4 0.005 17.1 0.0 6.6 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFP05557.1 - 2.4e-11 43.3 3.8 0.0019 18.0 0.4 6.1 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP05557.1 - 2.8e-11 43.0 11.5 1.6 9.3 0.0 9.3 10 1 0 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFP05557.1 - 2.4e-10 39.3 3.7 0.04 13.7 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat MIT PF04212.13 KFP05557.1 - 1.7e-06 27.8 6.5 0.01 15.7 0.2 4.1 3 1 0 3 3 2 2 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 KFP05557.1 - 1.8e-06 27.9 26.6 0.11 12.6 3.9 5.7 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.7 KFP05557.1 - 0.015 15.0 2.1 0.61 9.8 0.0 3.7 4 0 0 4 4 3 0 Mad3/BUB1 homology region 1 PPR PF01535.15 KFP05557.1 - 0.039 13.9 0.3 6.4 6.9 0.0 3.6 3 0 0 3 3 2 0 PPR repeat RPN7 PF10602.4 KFP05557.1 - 0.04 13.2 7.6 0.043 13.2 0.2 3.4 4 0 0 4 4 4 0 26S proteasome subunit RPN7 LNP1 PF15419.1 KFP05558.1 - 1.6e-52 178.1 23.9 2e-52 177.8 16.6 1.1 1 0 0 1 1 1 1 Leukemia NUP98 fusion partner 1 Neur_chan_memb PF02932.11 KFP05558.1 - 8.8 6.1 6.5 12 5.6 4.3 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF716 PF04819.7 KFP05559.1 - 5.8e-44 148.8 12.4 9.8e-44 148.1 8.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF716) 7tm_2 PF00002.19 KFP05560.1 - 1e-38 132.8 16.5 1.9e-38 131.9 11.5 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.16 KFP05560.1 - 9.4e-11 41.6 5.3 9.4e-11 41.6 3.7 1.9 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain NfeD PF01957.13 KFP05560.1 - 0.79 9.8 5.8 1.9 8.6 0.1 3.3 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding PB1 PF00564.19 KFP05561.1 - 6.5e-16 57.7 0.3 1.5e-15 56.6 0.2 1.6 2 0 0 2 2 2 1 PB1 domain fn3 PF00041.16 KFP05562.1 - 4e-17 62.1 9.5 2.9e-11 43.3 0.7 3.9 3 1 0 3 3 3 2 Fibronectin type III domain Interfer-bind PF09294.5 KFP05562.1 - 2.4e-05 24.3 1.3 0.15 12.1 0.0 3.5 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Phe_tRNA-synt_N PF02912.13 KFP05563.1 - 0.12 12.1 0.1 5 6.9 0.0 2.8 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain SEA PF01390.15 KFP05564.1 - 8.8e-36 121.8 1.0 5.2e-20 71.1 0.3 2.7 2 0 0 2 2 2 2 SEA domain EGF PF00008.22 KFP05564.1 - 0.0026 17.6 12.1 0.0032 17.3 3.2 2.5 2 0 0 2 2 2 2 EGF-like domain Arb2 PF09757.4 KFP05565.1 - 5.5e-22 78.0 0.0 1.4e-21 76.7 0.0 1.6 1 1 0 1 1 1 1 Arb2 domain PGAP1 PF07819.8 KFP05565.1 - 0.00086 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.17 KFP05565.1 - 0.033 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 KFP05565.1 - 0.044 13.6 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KFP05565.1 - 0.098 11.9 0.2 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DIM1 PF02966.11 KFP05566.1 - 3.3e-55 185.2 0.1 3.8e-55 185.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KFP05566.1 - 7.8e-06 25.5 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin tRNA_m1G_MT PF01746.16 KFP05567.1 - 4.4e-34 117.6 1.2 6.2e-34 117.2 0.1 1.7 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase CDH PF02611.10 KFP05567.1 - 0.018 14.3 0.1 0.045 12.9 0.0 1.7 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase PCNP PF15473.1 KFP05568.1 - 3.7e-71 238.3 13.3 4.1e-71 238.1 9.2 1.0 1 0 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family DUF4602 PF15375.1 KFP05568.1 - 0.052 13.6 3.7 0.092 12.8 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) DUF566 PF04484.7 KFP05568.1 - 2.2 7.7 5.2 2.4 7.5 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MRI PF15325.1 KFP05568.1 - 5.1 8.1 10.2 0.9 10.5 0.6 2.1 1 1 0 2 2 2 0 Modulator of retrovirus infection zf-H2C2_2 PF13465.1 KFP05569.1 - 3.5e-52 172.2 88.7 1.9e-08 34.2 0.2 14.0 14 1 0 14 14 14 10 Zinc-finger double domain zf-C2H2 PF00096.21 KFP05569.1 - 7.5e-41 136.0 95.0 0.00027 21.0 1.2 13.4 13 0 0 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP05569.1 - 1.8e-31 106.1 83.5 0.0026 17.9 0.4 13.3 13 0 0 13 13 13 11 C2H2-type zinc finger BTB PF00651.26 KFP05569.1 - 7.1e-23 80.7 1.9 1.5e-22 79.6 1.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_jaz PF12171.3 KFP05569.1 - 3.2e-16 58.9 62.8 0.00091 19.2 0.4 12.4 11 1 1 12 12 11 8 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP05569.1 - 3.7e-07 29.8 75.7 0.0019 18.0 0.3 12.6 13 0 0 13 13 13 6 C2H2-type zinc finger zf-met PF12874.2 KFP05569.1 - 7.9e-07 29.0 60.7 0.039 14.1 0.6 11.4 11 0 0 11 11 10 4 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP05569.1 - 1e-06 28.7 51.4 0.0015 18.5 0.5 8.5 5 3 2 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFP05569.1 - 4.1e-05 23.6 70.6 0.26 11.4 0.3 11.8 4 2 10 14 14 14 6 C2H2 type zinc-finger (2 copies) DZR PF12773.2 KFP05569.1 - 0.02 14.6 39.1 1.6 8.5 1.8 8.0 5 2 0 5 5 5 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 KFP05569.1 - 1.1 9.0 12.9 1.9 8.3 0.0 6.2 6 2 0 6 6 6 0 PhnA Zinc-Ribbon Ribosomal_L24e PF01246.15 KFP05570.1 - 1.5e-35 120.8 1.1 1.5e-35 120.8 0.8 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e Band_3_cyto PF07565.8 KFP05570.1 - 0.46 9.9 3.9 0.55 9.7 2.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Red1 PF07964.6 KFP05570.1 - 0.58 8.2 7.9 0.7 7.9 5.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 WTX PF09422.5 KFP05570.1 - 1.9 7.3 7.5 2.2 7.1 5.2 1.0 1 0 0 1 1 1 0 WTX protein DUF4658 PF15555.1 KFP05570.1 - 4 7.3 7.8 1.2 9.0 3.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4658) LRR_4 PF12799.2 KFP05571.1 - 2.4e-30 103.6 18.8 2.1e-08 33.5 2.1 4.6 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFP05571.1 - 6.6e-15 55.1 1.2 5.3e-12 45.6 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 KFP05571.1 - 1.6e-14 53.3 44.7 2.1e-08 33.7 4.9 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_7 PF13504.1 KFP05571.1 - 3.8e-06 26.2 13.3 10 6.8 0.1 8.0 7 0 0 7 7 7 1 Leucine rich repeat IQ PF00612.22 KFP05571.1 - 0.00021 20.6 0.1 0.0004 19.7 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_1 PF00560.28 KFP05571.1 - 0.00031 20.3 19.4 0.1 12.6 0.2 6.9 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 KFP05571.1 - 0.041 13.9 24.0 0.48 10.6 0.6 7.3 6 1 1 7 7 7 0 Leucine Rich repeat Thyroglobulin_1 PF00086.13 KFP05573.1 - 4.1e-30 102.9 27.6 3.9e-16 58.1 3.1 3.0 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.4 KFP05573.1 - 1.1e-14 54.3 0.7 2.5e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.10 KFP05573.1 - 2.3e-07 30.6 1.9 2.3e-07 30.6 1.3 2.2 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_1 PF00036.27 KFP05573.1 - 2.8e-05 23.1 0.2 0.78 9.1 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFP05573.1 - 2.9e-05 24.1 0.0 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair Kazal_1 PF00050.16 KFP05573.1 - 0.00025 21.0 3.9 0.00025 21.0 2.7 2.6 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_6 PF13405.1 KFP05573.1 - 0.00031 20.3 0.2 0.96 9.5 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFP05573.1 - 0.0081 15.4 0.0 0.25 10.7 0.0 3.3 3 0 0 3 3 3 1 EF hand Sulfotransfer_1 PF00685.22 KFP05574.1 - 9.6e-46 156.1 0.9 1.1e-45 156.0 0.6 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP05574.1 - 0.00094 20.1 0.0 0.001 20.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family DUF1266 PF06889.6 KFP05574.1 - 0.0023 17.7 0.6 0.003 17.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1266) Dapper PF15268.1 KFP05575.1 - 6.1e-216 719.6 44.4 6.8e-216 719.5 30.8 1.0 1 0 0 1 1 1 1 Dapper DivIC PF04977.10 KFP05575.1 - 0.0059 16.0 1.7 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Septum formation initiator HlyD PF00529.15 KFP05575.1 - 0.017 14.4 0.4 0.057 12.7 0.0 1.9 2 0 0 2 2 2 0 HlyD family secretion protein PspA_IM30 PF04012.7 KFP05575.1 - 0.71 9.1 6.0 0.071 12.4 0.7 1.7 2 0 0 2 2 2 0 PspA/IM30 family IncA PF04156.9 KFP05575.1 - 1.6 8.2 9.3 3.8 7.0 2.4 2.5 2 0 0 2 2 2 0 IncA protein LURAP PF14854.1 KFP05575.1 - 6.7 6.4 9.7 0.094 12.4 0.6 2.5 2 0 0 2 2 2 0 Leucine rich adaptor protein FERM_M PF00373.13 KFP05576.1 - 2.3e-19 69.7 0.4 6.2e-19 68.4 0.3 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFP05576.1 - 1e-17 63.9 0.4 2.3e-17 62.7 0.3 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FERM_C PF09380.5 KFP05576.1 - 4.4e-17 62.0 0.0 1.1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Kinesin PF00225.18 KFP05577.1 - 5.6e-82 275.1 0.0 1.6e-46 158.5 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Geminin PF07412.7 KFP05577.1 - 0.15 11.7 3.6 5.3 6.6 0.0 2.6 3 0 0 3 3 3 0 Geminin UNC-93 PF05978.11 KFP05579.1 - 2.6e-11 43.2 8.7 2.6e-11 43.2 6.0 3.3 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KFP05579.1 - 1.2e-08 34.1 31.7 3.5e-05 22.7 9.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFP05579.1 - 0.00026 19.5 21.1 0.00034 19.1 2.4 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein DUF2306 PF10067.4 KFP05579.1 - 0.88 9.7 5.1 18 5.5 0.1 3.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) Ribonuclease_T2 PF00445.13 KFP05580.1 - 4.2e-39 134.1 4.3 4.9e-39 133.9 3.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family Pkinase PF00069.20 KFP05581.1 - 3.2e-148 491.9 0.0 2.1e-73 246.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05581.1 - 1.4e-77 260.3 0.0 3.1e-41 141.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFP05581.1 - 8.7e-15 54.4 0.0 3.6e-07 29.4 0.0 3.1 3 1 0 3 3 3 2 Kinase-like Kdo PF06293.9 KFP05581.1 - 3.9e-10 39.1 0.0 1.6e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KFP05581.1 - 7.3e-09 36.0 1.0 1.4e-08 35.0 0.7 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 KFP05581.1 - 4e-06 26.7 0.0 0.097 12.3 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP05581.1 - 4.4e-06 26.1 0.0 0.0058 15.9 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFP05581.1 - 0.0013 18.1 0.1 0.16 11.3 0.0 2.7 3 0 0 3 3 3 1 RIO1 family tRNA-synt_1f PF01921.13 KFP05581.1 - 0.16 10.5 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Choline_kinase PF01633.15 KFP05581.1 - 0.19 11.2 0.0 20 4.6 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase MPC PF03650.8 KFP05583.1 - 1.3e-34 118.7 0.2 1.3e-34 118.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Got1 PF04178.7 KFP05584.1 - 4.6e-30 104.1 14.3 6.1e-30 103.7 9.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Polysacc_synt_C PF14667.1 KFP05584.1 - 0.03 14.1 9.6 0.041 13.6 6.6 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Na_Ca_ex PF01699.19 KFP05584.1 - 0.22 11.0 8.1 0.035 13.7 2.5 1.8 1 1 1 2 2 2 0 Sodium/calcium exchanger protein DUF1686 PF07937.6 KFP05584.1 - 0.39 10.3 2.8 0.12 11.9 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) DUF3429 PF11911.3 KFP05584.1 - 1.3 9.0 10.2 0.087 12.7 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) DUF4064 PF13273.1 KFP05584.1 - 1.9 8.6 7.5 10 6.3 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) 7TMR-DISM_7TM PF07695.6 KFP05584.1 - 2.2 7.8 15.2 5.9 6.5 3.0 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling PTPS_related PF10131.4 KFP05584.1 - 3.6 5.6 10.4 3.8 5.5 7.2 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DoxX_2 PF13564.1 KFP05584.1 - 4.2 7.3 10.7 9.4 6.2 3.2 2.1 1 1 1 2 2 2 0 DoxX-like family DUF4149 PF13664.1 KFP05584.1 - 5.9 7.0 9.8 13 5.9 5.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) Mad3_BUB1_I PF08311.7 KFP05585.1 - 3.3e-36 123.8 0.0 1.3e-35 121.9 0.0 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KFP05585.1 - 1.7e-17 63.4 0.0 3.3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05585.1 - 9.8e-08 31.3 0.0 1.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.12 KFP05586.1 - 7.6e-90 300.4 0.0 1e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP05586.1 - 1.7e-42 145.4 0.0 2.3e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ig_2 PF13895.1 KFP05586.1 - 4.8e-15 55.4 0.0 2.9e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain fn3 PF00041.16 KFP05586.1 - 1.5e-14 53.8 0.0 1.4e-06 28.3 0.1 2.9 3 0 0 3 3 3 2 Fibronectin type III domain I-set PF07679.11 KFP05586.1 - 6.9e-11 41.8 0.0 0.00011 21.9 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP05586.1 - 3.5e-10 40.2 3.1 1.6e-05 25.3 0.3 3.2 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFP05586.1 - 7.3e-08 32.4 0.1 0.033 14.3 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFP05586.1 - 0.00014 21.7 0.2 0.061 13.2 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin V-set domain Kinase-like PF14531.1 KFP05586.1 - 0.25 10.2 0.0 0.42 9.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-CCCH PF00642.19 KFP05587.1 - 8e-11 41.3 22.0 4.4e-05 23.0 0.9 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFP05587.1 - 0.25 11.3 23.5 0.17 11.9 1.1 3.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type SNAP PF14938.1 KFP05588.1 - 8.1e-101 336.8 20.6 9e-101 336.7 14.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KFP05588.1 - 1e-08 34.9 10.6 3.3e-05 23.7 3.2 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFP05588.1 - 8.1e-05 22.1 21.3 0.0086 15.7 2.1 4.4 2 1 3 5 5 5 4 TPR repeat TPR_7 PF13176.1 KFP05588.1 - 9.6e-05 21.8 11.9 0.18 11.6 0.0 6.2 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFP05588.1 - 0.00063 19.4 15.3 1.3 9.1 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFP05588.1 - 0.00066 19.9 10.5 5.6 7.6 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFP05588.1 - 0.0012 18.7 3.2 5.5 7.0 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFP05588.1 - 0.0012 19.4 5.2 0.082 13.6 1.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFP05588.1 - 0.0059 17.1 5.7 35 5.4 0.0 5.1 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFP05588.1 - 0.013 15.2 16.5 0.25 11.2 0.7 5.2 5 1 2 7 7 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFP05588.1 - 0.024 14.9 7.5 0.11 12.8 1.7 3.3 2 2 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KFP05588.1 - 0.034 14.0 13.0 5.8 6.8 0.0 5.2 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain NSF PF02071.15 KFP05588.1 - 0.066 13.7 35.6 0.45 11.2 1.8 8.2 8 0 0 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat IL4 PF00727.13 KFP05588.1 - 0.14 12.0 0.6 0.51 10.2 0.1 2.1 2 0 0 2 2 2 0 Interleukin 4 CBP PF12192.3 KFP05588.1 - 0.86 9.6 4.7 11 6.1 0.2 4.1 4 2 0 4 4 4 0 Fungal calcium binding protein Sel1 PF08238.7 KFP05588.1 - 4.8 7.9 13.2 3.3 8.4 0.4 4.5 5 1 1 6 6 4 0 Sel1 repeat zf-H2C2_2 PF13465.1 KFP05589.1 - 4.5e-77 250.7 84.3 3.2e-10 39.7 0.3 12.2 12 0 0 12 12 12 12 Zinc-finger double domain zf-C2H2 PF00096.21 KFP05589.1 - 2.4e-51 169.0 97.4 3.8e-06 26.9 0.5 12.1 12 0 0 12 12 12 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP05589.1 - 8e-39 129.1 94.6 2.7e-06 27.3 0.2 12.1 12 0 0 12 12 12 12 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP05589.1 - 4.7e-20 71.1 57.9 0.018 15.1 0.0 12.3 12 0 0 12 12 12 9 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP05589.1 - 2.3e-17 62.5 69.6 0.00066 19.7 0.2 12.0 12 0 0 12 12 12 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP05589.1 - 1.3e-11 43.9 89.0 0.013 15.3 2.2 13.5 12 2 0 12 12 12 7 C2H2-type zinc finger BolA PF01722.13 KFP05589.1 - 1.4e-06 28.1 12.3 0.096 12.6 0.8 6.0 3 2 3 6 6 6 3 BolA-like protein C1_1 PF00130.17 KFP05589.1 - 3.1e-05 23.6 59.2 0.0011 18.6 1.3 8.9 2 2 5 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) RRN7 PF11781.3 KFP05589.1 - 0.0006 19.2 47.9 1.7 8.2 0.1 11.5 12 0 0 12 12 12 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 KFP05589.1 - 0.00079 19.0 39.6 1.3 8.7 0.0 9.0 8 0 0 8 8 8 4 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 KFP05589.1 - 0.033 14.1 73.5 1.2 9.1 0.0 11.7 7 3 4 11 11 11 0 Zinc ribbon domain Prok-RING_1 PF14446.1 KFP05589.1 - 0.04 13.6 57.9 0.94 9.2 0.1 12.1 11 1 0 11 11 11 0 Prokaryotic RING finger family 1 Ta0938 PF11494.3 KFP05589.1 - 0.068 13.2 22.4 2 8.5 0.3 6.0 2 2 5 7 7 7 0 Ta0938 zf-FCS PF06467.9 KFP05589.1 - 0.16 11.6 45.1 2.7 7.6 0.2 9.0 5 2 4 9 9 9 0 MYM-type Zinc finger with FCS sequence motif IBD PF10416.4 KFP05589.1 - 0.83 9.4 5.9 16 5.3 0.1 4.1 3 1 1 5 5 5 0 Transcription-initiator DNA-binding domain IBD C1_4 PF07975.7 KFP05589.1 - 6 6.9 57.9 1.1 9.3 3.3 8.5 1 1 8 10 10 10 0 TFIIH C1-like domain ARS2 PF04959.8 KFP05589.1 - 6.6 6.8 10.1 0.51 10.5 1.9 2.8 2 1 1 3 3 3 0 Arsenite-resistance protein 2 7tm_1 PF00001.16 KFP05590.1 - 1.7e-67 227.2 12.9 2e-67 227.0 8.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05590.1 - 4.6e-15 55.4 2.9 5.4e-15 55.2 2.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP05590.1 - 4.8e-08 32.4 1.9 4.8e-08 32.4 1.3 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srv PF10323.4 KFP05590.1 - 0.00055 19.1 2.0 0.0011 18.2 1.4 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srw PF10324.4 KFP05590.1 - 0.00075 18.7 5.1 0.011 14.8 0.0 2.4 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Alg6_Alg8 PF03155.10 KFP05590.1 - 0.013 14.3 1.3 0.013 14.3 0.9 2.0 2 0 0 2 2 2 0 ALG6, ALG8 glycosyltransferase family Herpes_US9 PF06072.6 KFP05590.1 - 0.038 13.8 0.5 0.038 13.8 0.4 2.5 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF454 PF04304.8 KFP05590.1 - 0.19 11.8 4.8 1.5 8.9 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Fork_head PF00250.13 KFP05591.1 - 3.8e-47 158.2 0.3 8.8e-47 157.0 0.2 1.6 1 0 0 1 1 1 1 Fork head domain Fork_head_N PF08430.7 KFP05591.1 - 5.6e-25 88.3 45.3 5.6e-25 88.3 31.4 2.3 2 0 0 2 2 2 1 Forkhead N-terminal region HNF_C PF09354.5 KFP05591.1 - 2e-22 80.0 11.1 2e-22 80.0 7.7 3.8 2 1 2 4 4 4 1 HNF3 C-terminal domain Innate_immun PF12782.2 KFP05591.1 - 4.9 6.2 10.5 8.6 5.4 7.3 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Homeobox PF00046.24 KFP05592.1 - 3.9e-15 55.2 0.0 8.6e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP05592.1 - 0.045 13.4 0.4 0.045 13.4 0.2 2.1 3 0 0 3 3 3 0 Homeobox KN domain XRN_N PF03159.13 KFP05594.1 - 7.3e-115 382.3 0.1 1.4e-114 381.4 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Rap_GAP PF02145.10 KFP05595.1 - 1.1e-64 217.2 0.0 2e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Pyr_redox_2 PF07992.9 KFP05596.1 - 0.0033 17.3 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFP05596.1 - 0.065 13.2 0.1 8.4 6.3 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_10 PF13673.1 KFP05596.1 - 0.088 12.9 0.2 2.9 8.0 0.0 3.0 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain Na_Ca_ex PF01699.19 KFP05597.1 - 4.1e-55 185.2 34.6 6.3e-31 106.8 7.7 2.6 2 1 1 3 3 3 2 Sodium/calcium exchanger protein PBP1_TM PF14812.1 KFP05597.1 - 0.0063 16.7 1.2 0.017 15.3 0.8 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3449 PF11931.3 KFP05597.1 - 0.0076 15.7 1.6 0.013 15.0 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Herpes_LMP1 PF05297.6 KFP05597.1 - 0.0092 14.9 0.6 0.0092 14.9 0.4 3.2 3 0 0 3 3 3 1 Herpesvirus latent membrane protein 1 (LMP1) TFIIA PF03153.8 KFP05597.1 - 0.014 15.2 4.4 0.018 14.9 3.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.3 KFP05597.1 - 0.16 11.9 9.4 0.24 11.3 6.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 KFP05597.1 - 0.31 11.3 10.5 0.69 10.1 7.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 KFP05597.1 - 0.46 10.2 6.2 0.38 10.5 3.1 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal AF1Q PF15017.1 KFP05597.1 - 0.56 10.1 9.9 1.3 9.0 6.9 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Nucleoplasmin PF03066.10 KFP05597.1 - 0.68 9.4 11.6 0.56 9.7 6.3 1.9 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 KFP05597.1 - 1.5 8.0 9.7 2.3 7.3 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein SPC25 PF06703.6 KFP05597.1 - 1.8 8.1 5.9 2.1 7.8 0.3 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Nop14 PF04147.7 KFP05597.1 - 2.6 5.8 11.3 3.6 5.3 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KFP05597.1 - 3 6.7 6.9 5.5 5.8 4.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.14 KFP05597.1 - 4.8 7.6 7.8 10 6.5 5.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Daxx PF03344.10 KFP05597.1 - 7.5 4.9 14.2 10 4.4 9.9 1.1 1 0 0 1 1 1 0 Daxx Family LAT PF15234.1 KFP05597.1 - 7.7 5.9 10.9 14 5.1 7.6 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells DUF843 PF05814.6 KFP05597.1 - 8.7 6.2 8.7 0.87 9.4 1.1 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) VPS9 PF02204.13 KFP05598.1 - 3.6e-23 81.5 0.9 6.7e-23 80.6 0.1 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RA PF00788.18 KFP05598.1 - 3.3e-13 49.9 0.2 7.7e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH2 PF00017.19 KFP05598.1 - 0.0075 16.0 0.0 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 SH2 domain RelB PF04221.7 KFP05598.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 RelB antitoxin Acetyltransf_1 PF00583.19 KFP05599.1 - 2.6e-14 53.0 0.1 4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFP05599.1 - 1.4e-08 34.3 0.1 2.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KFP05599.1 - 3.6e-07 30.2 0.0 5.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFP05599.1 - 2.7e-05 24.2 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFP05599.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C2 PF00648.16 KFP05600.1 - 1e-145 484.3 0.0 1.3e-145 484.0 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFP05600.1 - 3.2e-52 176.0 0.0 5.3e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 KFP05600.1 - 5.9e-09 34.5 0.2 0.0023 17.1 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KFP05600.1 - 1.6e-07 30.5 0.0 0.0024 17.5 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFP05600.1 - 6e-07 28.9 2.5 0.00012 21.5 0.0 3.6 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 KFP05600.1 - 8.2e-06 25.8 0.2 0.089 12.9 0.0 2.5 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP05600.1 - 0.0032 16.7 0.1 0.61 9.5 0.0 2.8 2 0 0 2 2 2 1 EF hand DUF2207 PF09972.4 KFP05600.1 - 0.16 10.5 7.5 0.054 12.0 2.5 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RVT_1 PF00078.22 KFP05603.1 - 4.3e-28 98.1 0.0 5.5e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFP05603.1 - 5.4e-05 22.6 0.2 0.00012 21.5 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVT_1 PF00078.22 KFP05604.1 - 1.3e-14 54.0 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAC PF01849.13 KFP05605.1 - 4.1e-24 83.8 0.3 6.1e-24 83.3 0.2 1.3 1 0 0 1 1 1 1 NAC domain LolA PF03548.10 KFP05605.1 - 0.083 12.5 0.6 0.11 12.1 0.4 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA dUTPase PF00692.14 KFP05606.1 - 2.4e-21 75.5 0.1 3.2e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP05606.1 - 0.003 17.4 0.3 0.0082 16.0 0.2 1.8 1 1 1 2 2 2 1 Retroviral aspartyl protease zf-Di19 PF05605.7 KFP05607.1 - 2.8e-05 24.1 0.1 6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Di19_C PF14571.1 KFP05607.1 - 7.5e-05 22.9 2.5 7.5e-05 22.9 1.8 2.4 1 1 1 2 2 2 1 Stress-induced protein Di19, C-terminal TFIIA PF03153.8 KFP05607.1 - 0.6 9.9 6.6 0.72 9.6 4.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1282 PF06930.7 KFP05608.1 - 0.033 13.8 2.2 0.054 13.1 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) SHR3_chaperone PF08229.6 KFP05608.1 - 0.22 10.4 3.0 0.37 9.7 2.1 1.8 1 1 0 1 1 1 0 ER membrane protein SH3 SUR7 PF06687.7 KFP05608.1 - 4.9 6.6 15.6 30 4.0 10.8 2.2 1 1 0 1 1 1 0 SUR7/PalI family TatC PF00902.13 KFP05608.1 - 9.3 5.5 13.1 4.2 6.7 2.0 2.2 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) Kinesin PF00225.18 KFP05609.1 - 1e-60 205.2 0.0 1.6e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Asparaginase PF00710.15 KFP05610.1 - 4.4e-111 370.7 0.0 9.2e-111 369.6 0.0 1.5 2 0 0 2 2 2 1 Asparaginase Ank_2 PF12796.2 KFP05610.1 - 8.4e-21 74.1 0.0 1.2e-18 67.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP05610.1 - 9e-19 67.4 0.1 1.2e-11 44.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFP05610.1 - 4.1e-15 54.7 0.0 9e-09 34.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFP05610.1 - 4e-14 52.2 0.6 2.6e-10 40.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP05610.1 - 3.4e-12 45.3 0.4 1.9e-06 27.5 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat DDE_Tnp_1_7 PF13843.1 KFP05610.1 - 0.084 11.9 0.0 0.19 10.7 0.0 1.5 2 0 0 2 2 2 0 Transposase IS4 HA2 PF04408.18 KFP05611.1 - 4.1e-16 58.8 0.0 8.8e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) TUDOR PF00567.19 KFP05611.1 - 2.7e-14 53.0 0.0 2.2e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 Tudor domain Helicase_C PF00271.26 KFP05611.1 - 2.6e-12 46.4 0.0 5.9e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_6 PF14259.1 KFP05611.1 - 0.04 13.8 0.0 0.089 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RD3 PF14473.1 KFP05612.1 - 3.7e-49 165.6 2.5 5e-49 165.1 1.8 1.1 1 0 0 1 1 1 1 RD3 protein Mit_proteolip PF08039.6 KFP05613.1 - 1.9e-10 40.5 2.5 1.9e-10 40.5 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial proteolipid Ank PF00023.25 KFP05614.1 - 5.5e-19 66.9 1.3 5.1e-09 35.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFP05614.1 - 1e-17 64.2 0.1 2.1e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP05614.1 - 6.1e-14 52.0 0.4 1.3e-09 38.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_1 PF00018.23 KFP05614.1 - 8.8e-14 50.6 1.5 1.7e-13 49.6 1.1 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.1 KFP05614.1 - 1.4e-12 46.5 1.2 8.8e-06 25.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.1 KFP05614.1 - 5.5e-12 45.0 0.2 1.1e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.1 KFP05614.1 - 1.6e-11 44.0 1.9 2.3e-09 37.2 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_2 PF07653.12 KFP05614.1 - 6.8e-10 38.2 0.0 1.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 KFP05614.1 - 0.0028 17.2 20.7 0.0028 17.2 14.3 2.6 2 0 0 2 2 2 1 IncA protein GAGA_bind PF06217.7 KFP05614.1 - 0.4 10.6 11.0 0.5 10.2 0.1 2.6 2 0 0 2 2 2 0 GAGA binding protein-like family FYVE PF01363.16 KFP05615.1 - 1.1e-11 44.4 23.9 2.1e-11 43.5 16.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KFP05615.1 - 7.9 6.4 20.3 49 3.8 13.3 2.5 1 1 1 2 2 2 0 FYVE-type zinc finger Rad51 PF08423.6 KFP05616.1 - 2.9e-26 91.9 0.0 2.8e-25 88.7 0.0 2.0 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFP05616.1 - 2.7e-08 33.4 0.0 4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KFP05616.1 - 3.4e-05 23.0 0.1 0.032 13.2 0.0 2.2 1 1 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 KFP05616.1 - 0.00014 21.1 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 KaiC RNA_pol_A_CTD PF03118.10 KFP05616.1 - 0.0038 16.6 0.1 0.0082 15.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH_5 PF14520.1 KFP05616.1 - 0.0086 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Phage-MuB_C PF09077.6 KFP05616.1 - 0.096 12.3 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Mu B transposition protein, C terminal TPR_12 PF13424.1 KFP05617.1 - 6.3e-74 243.9 27.7 2.8e-23 81.6 1.0 5.9 4 1 3 7 7 6 5 Tetratricopeptide repeat Rab5-bind PF09311.6 KFP05617.1 - 3.9e-68 228.9 15.4 4.5e-66 222.1 9.7 4.2 5 0 0 5 5 4 2 Rabaptin-like protein TPR_10 PF13374.1 KFP05617.1 - 8.3e-65 213.0 12.4 4.9e-16 58.0 0.0 6.8 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KFP05617.1 - 6e-31 103.7 18.7 6.6e-06 25.5 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFP05617.1 - 5.2e-29 98.6 31.3 1.1e-07 31.0 0.3 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFP05617.1 - 2.8e-25 87.7 18.8 2.4e-11 43.1 1.5 4.9 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 KFP05617.1 - 1e-20 71.9 26.9 0.00039 20.1 1.8 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFP05617.1 - 5.4e-20 71.5 10.4 2.8e-06 27.8 0.1 4.8 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFP05617.1 - 8.7e-15 54.8 10.8 1.2e-05 25.5 0.2 4.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFP05617.1 - 9.6e-15 53.7 10.4 0.18 12.4 0.3 7.0 3 1 4 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFP05617.1 - 1.7e-11 43.3 10.4 0.065 13.4 0.1 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP05617.1 - 2.9e-11 42.2 19.7 0.073 12.8 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KFP05617.1 - 8.5e-11 41.8 9.4 6.7e-06 26.1 2.2 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFP05617.1 - 2.4e-07 30.5 0.0 8.8 7.0 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.15 KFP05617.1 - 0.00041 20.1 3.0 0.16 11.9 0.0 4.5 7 0 0 7 7 3 1 PPR repeat DUF972 PF06156.8 KFP05617.1 - 0.0041 17.4 6.0 0.0041 17.4 4.2 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF972) PPR_3 PF13812.1 KFP05617.1 - 0.0056 16.8 1.1 3.3 8.2 0.0 4.5 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TMF_DNA_bd PF12329.3 KFP05617.1 - 0.01 15.6 10.3 0.01 15.6 7.1 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SHNi-TPR PF10516.4 KFP05617.1 - 0.014 14.5 4.0 5.8 6.2 0.0 4.6 5 0 0 5 5 5 0 SHNi-TPR PPR_2 PF13041.1 KFP05617.1 - 0.066 13.1 0.3 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family TPR_6 PF13174.1 KFP05617.1 - 0.25 11.8 0.2 0.25 11.8 0.1 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat COG2 PF06148.6 KFP05617.1 - 0.38 10.6 8.7 0.2 11.5 3.9 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3366 PF11846.3 KFP05617.1 - 2.4 7.9 8.8 12 5.7 1.7 4.1 2 1 1 4 4 3 0 Domain of unknown function (DUF3366) TPR_3 PF07720.7 KFP05617.1 - 7.2 6.5 17.2 2.1 8.2 0.9 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF2315 PF10231.4 KFP05618.1 - 5.2e-49 165.3 1.1 6.2e-49 165.1 0.8 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2315) GCD14 PF08704.5 KFP05619.1 - 6.1e-110 366.5 0.0 7.3e-110 366.2 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KFP05619.1 - 2.1e-07 30.6 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP05619.1 - 5.1e-07 30.2 0.0 8.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFP05619.1 - 2.5e-05 23.9 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KFP05619.1 - 4.9e-05 23.3 0.0 8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.1 KFP05619.1 - 0.0037 16.7 0.6 0.0073 15.8 0.4 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.1 KFP05619.1 - 0.0067 17.2 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KFP05619.1 - 0.0094 15.0 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 KFP05619.1 - 0.015 15.6 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFP05619.1 - 0.025 15.0 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFP05619.1 - 0.031 14.7 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KFP05619.1 - 0.085 11.9 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ATP-gua_Ptrans PF00217.14 KFP05620.1 - 6.6e-91 303.9 0.0 9e-91 303.5 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 KFP05620.1 - 8e-35 118.8 0.0 1.2e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain Pkinase PF00069.20 KFP05621.1 - 3.8e-78 262.2 0.0 6e-78 261.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05621.1 - 2.7e-45 154.4 0.0 5.3e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFP05621.1 - 7.2e-19 66.9 0.0 1.2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 KFP05621.1 - 1.3e-07 30.8 0.0 2.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFP05621.1 - 6.8e-05 22.2 0.3 0.00015 21.1 0.2 1.5 1 0 0 1 1 1 1 RIO1 family UBA PF00627.26 KFP05621.1 - 0.00084 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Kdo PF06293.9 KFP05621.1 - 0.0025 16.8 0.1 0.0045 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.6 KFP05621.1 - 0.041 14.0 0.2 0.13 12.4 0.2 1.9 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YrbL-PhoP_reg PF10707.4 KFP05621.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL eIF-5_eIF-2B PF01873.12 KFP05622.1 - 9.4e-47 157.7 0.6 4.4e-46 155.6 0.1 2.1 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 KFP05622.1 - 1.4e-25 89.0 2.8 1.4e-25 89.0 2.0 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon LIN37 PF15306.1 KFP05622.1 - 3.5 7.5 7.4 0.83 9.6 2.2 2.1 2 0 0 2 2 2 0 LIN37 PGA2 PF07543.7 KFP05622.1 - 4.9 6.9 10.5 8.3 6.2 0.4 2.8 2 0 0 2 2 2 0 Protein trafficking PGA2 Luciferase_N PF05295.6 KFP05623.1 - 0.081 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Mating_N PF12731.2 KFP05623.1 - 0.12 12.2 2.3 0.29 11.0 1.6 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 Sec6 PF06046.8 KFP05624.1 - 6.2e-68 229.2 11.3 7e-68 229.0 7.8 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 RE_XamI PF09572.5 KFP05624.1 - 0.029 13.8 0.1 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 XamI restriction endonuclease Sec6 PF06046.8 KFP05625.1 - 5.4e-60 203.0 7.0 6.9e-60 202.6 4.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF1767 PF08585.7 KFP05625.1 - 0.037 14.2 1.1 5.5 7.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1767) SBP PF03110.9 KFP05625.1 - 0.078 13.2 0.3 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 SBP domain Lbh PF15317.1 KFP05627.1 - 3e-30 104.3 2.7 3.5e-30 104.1 1.9 1.1 1 0 0 1 1 1 1 Cardiac transcription factor regulator, Developmental protein CNH PF00780.17 KFP05628.1 - 9.1e-69 231.9 0.1 1.7e-68 231.0 0.0 1.4 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFP05628.1 - 9.1e-55 185.6 1.9 1.1e-54 185.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05628.1 - 6.8e-29 100.7 0.0 6.8e-29 100.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DMPK_coil PF08826.5 KFP05628.1 - 7.8e-26 89.7 11.6 7.8e-26 89.7 8.1 9.3 7 2 3 10 10 9 1 DMPK coiled coil domain like C1_1 PF00130.17 KFP05628.1 - 1.2e-09 37.7 5.4 2.5e-09 36.7 3.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFP05628.1 - 0.00023 21.5 2.2 0.00049 20.5 1.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Myosin_tail_1 PF01576.14 KFP05628.1 - 0.00054 17.8 105.1 0.0033 15.2 49.0 2.1 1 1 1 2 2 2 2 Myosin tail PBD PF00786.23 KFP05628.1 - 0.0019 18.5 0.7 0.0062 16.9 0.1 2.3 2 0 0 2 2 1 1 P21-Rho-binding domain Reo_sigmaC PF04582.7 KFP05628.1 - 0.017 14.2 14.7 0.99 8.5 0.6 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 KFP05628.1 - 0.043 13.2 88.2 0.071 12.5 12.6 4.7 1 1 2 4 4 4 0 Intermediate filament protein Baculo_PEP_C PF04513.7 KFP05628.1 - 1.3 8.8 20.2 0.65 9.8 0.4 4.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KFP05628.1 - 5.9 6.4 100.4 0.88 9.1 17.4 5.6 2 1 3 5 5 4 0 IncA protein Amnionless PF14828.1 KFP05629.1 - 1.9e-115 385.8 0.0 2.1e-115 385.6 0.0 1.0 1 0 0 1 1 1 1 Amnionless MATH PF00917.21 KFP05630.1 - 1.1e-28 99.8 0.0 1.3e-27 96.4 0.0 2.5 2 0 0 2 2 2 1 MATH domain zf-TRAF PF02176.13 KFP05630.1 - 4.3e-25 87.8 23.9 2e-16 60.0 5.2 4.4 2 2 2 4 4 3 2 TRAF-type zinc finger Sina PF03145.11 KFP05630.1 - 0.00016 21.4 23.5 0.018 14.6 1.1 3.7 1 1 3 4 4 4 2 Seven in absentia protein family FliJ PF02050.11 KFP05630.1 - 0.0012 18.8 9.0 0.0024 17.9 6.3 1.4 1 0 0 1 1 1 1 Flagellar FliJ protein zf-C3HC4 PF00097.20 KFP05630.1 - 0.0013 18.3 14.6 0.0013 18.3 10.1 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Cast PF10174.4 KFP05630.1 - 0.0018 16.4 8.4 0.0027 15.8 5.8 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone zf-RING_5 PF14634.1 KFP05630.1 - 0.0035 17.0 13.8 0.0035 17.0 9.5 3.3 3 2 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFP05630.1 - 0.006 16.5 13.6 0.006 16.5 9.4 3.1 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP05630.1 - 0.0066 16.3 12.1 0.0066 16.3 8.4 2.7 2 1 1 3 3 1 1 zinc finger of C3HC4-type, RING BLOC1_2 PF10046.4 KFP05630.1 - 0.014 15.4 7.1 0.42 10.7 3.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HrpB7 PF09486.5 KFP05630.1 - 0.019 14.9 3.2 0.052 13.4 0.2 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) zf-RING_6 PF14835.1 KFP05630.1 - 0.092 12.5 6.4 0.1 12.3 3.1 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Tropomyosin_1 PF12718.2 KFP05630.1 - 0.096 12.5 13.7 0.22 11.3 9.5 1.7 1 1 0 1 1 1 0 Tropomyosin like IncA PF04156.9 KFP05630.1 - 0.11 12.1 12.1 0.19 11.2 8.4 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KFP05630.1 - 0.13 10.0 7.1 0.18 9.6 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 KFP05630.1 - 0.28 10.9 17.1 0.57 9.9 9.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Med9 PF07544.8 KFP05630.1 - 0.38 10.5 10.9 0.94 9.2 3.5 2.9 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.1 KFP05630.1 - 0.39 9.8 15.1 0.094 11.8 7.7 2.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 KFP05630.1 - 0.71 9.0 8.4 1.1 8.4 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.6 KFP05630.1 - 0.87 9.0 8.0 0.17 11.3 2.6 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 SNARE PF05739.14 KFP05630.1 - 1.1 9.0 7.6 0.37 10.5 2.5 2.1 2 0 0 2 2 2 0 SNARE domain ADIP PF11559.3 KFP05630.1 - 1.5 8.7 18.3 0.25 11.2 8.5 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KFP05630.1 - 2.9 6.9 6.0 1.9 7.6 1.2 1.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Myb_DNA-binding PF00249.26 KFP05631.1 - 1.1e-16 60.6 0.4 1.8e-08 34.3 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELM2 PF01448.19 KFP05631.1 - 5.5e-05 23.7 0.7 0.0002 21.9 0.0 2.4 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-bind_6 PF13921.1 KFP05631.1 - 0.00053 20.0 3.2 0.44 10.6 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF2422 PF10337.4 KFP05631.1 - 1.4 7.6 3.9 2.1 7.0 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Ank_2 PF12796.2 KFP05632.1 - 8.1e-14 51.7 0.0 9.7e-07 29.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP05632.1 - 2.1e-08 34.1 0.4 2.4e-07 30.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP05632.1 - 1.7e-07 31.5 0.3 1.1e-05 25.8 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KFP05632.1 - 9.4e-07 28.3 1.8 3.2e-06 26.6 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFP05632.1 - 0.015 15.4 0.5 0.32 11.3 0.1 3.1 3 0 0 3 3 3 0 Ankyrin repeat Hyd_WA PF06462.7 KFP05633.1 - 4.9e-50 166.8 22.0 1.7e-08 33.9 0.5 9.1 9 0 0 9 9 9 6 Propeller WD40 PF00400.27 KFP05633.1 - 0.0029 17.4 0.0 0.029 14.2 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat SART-1 PF03343.8 KFP05633.1 - 0.025 12.9 0.4 0.042 12.2 0.3 1.3 1 0 0 1 1 1 0 SART-1 family DUF3256 PF11644.3 KFP05634.1 - 0.006 16.1 0.9 0.0084 15.6 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3256) AAA_8 PF12780.2 KFP05634.1 - 0.031 13.2 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Med17 PF10156.4 KFP05634.1 - 0.035 12.3 2.0 0.33 9.1 0.2 2.0 2 0 0 2 2 2 0 Subunit 17 of Mediator complex zf-C2H2 PF00096.21 KFP05636.1 - 0.03 14.6 0.1 0.072 13.4 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pkinase PF00069.20 KFP05637.1 - 5.4e-70 235.5 0.0 6.8e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05637.1 - 1.3e-32 112.8 0.0 1.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP05637.1 - 2e-05 23.7 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP05637.1 - 0.0069 15.4 0.0 0.02 13.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 KFP05638.1 - 2.7e-16 58.7 12.0 8.6e-07 28.6 0.2 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 KFP05638.1 - 0.0013 18.3 0.3 1.7 8.3 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KFP05638.1 - 0.011 15.4 0.0 0.076 12.7 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A HSP90 PF00183.13 KFP05639.1 - 4.2e-273 906.5 39.2 5.1e-273 906.2 27.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KFP05639.1 - 3.2e-12 46.1 0.0 7.4e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFP05639.1 - 5.8e-12 45.4 0.1 5.8e-12 45.4 0.1 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.9 KFP05639.1 - 0.4 8.6 13.7 0.83 7.6 9.5 1.4 1 0 0 1 1 1 0 CDC45-like protein SF3a60_bindingd PF12108.3 KFP05639.1 - 0.85 9.2 5.4 6.1 6.4 0.1 2.8 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF1510 PF07423.6 KFP05639.1 - 7 5.9 26.1 0.21 10.9 11.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Dynein_heavy PF03028.10 KFP05641.1 - 7.2e-238 791.2 0.5 7.2e-238 791.2 0.4 2.2 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 KFP05641.1 - 1.5e-195 650.9 9.0 1.5e-195 650.9 6.3 4.9 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KFP05641.1 - 8e-118 393.4 15.0 8e-118 393.4 10.4 5.1 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KFP05641.1 - 6.8e-82 274.4 0.0 3.2e-81 272.2 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KFP05641.1 - 5e-44 149.8 0.2 4.7e-43 146.6 0.0 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KFP05641.1 - 6.1e-44 150.0 0.0 4.2e-43 147.2 0.0 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KFP05641.1 - 3.2e-42 144.5 14.6 3.2e-42 144.5 10.1 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KFP05641.1 - 3.8e-30 104.4 0.0 2.5e-12 46.7 0.0 5.9 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KFP05641.1 - 3.2e-21 75.6 0.0 1.1e-20 73.8 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KFP05641.1 - 2.7e-13 50.1 5.9 0.036 14.1 0.0 7.0 8 0 0 8 8 6 4 AAA domain AAA PF00004.24 KFP05641.1 - 1.1e-12 48.3 0.0 0.04 14.1 0.0 5.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFP05641.1 - 1.8e-11 44.1 0.3 0.022 14.6 0.0 6.3 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.1 KFP05641.1 - 1.5e-10 41.3 5.6 0.014 15.4 0.0 6.4 7 0 0 7 7 6 3 AAA ATPase domain AAA_17 PF13207.1 KFP05641.1 - 1.8e-09 38.4 0.0 0.056 14.2 0.0 6.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 KFP05641.1 - 2.1e-09 37.7 9.2 0.082 13.2 0.0 7.7 8 0 0 8 8 7 2 AAA domain Mg_chelatase PF01078.16 KFP05641.1 - 5.8e-07 28.8 0.5 0.11 11.6 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFP05641.1 - 5.1e-06 26.1 0.1 0.34 10.6 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain IstB_IS21 PF01695.12 KFP05641.1 - 6.4e-05 22.4 1.3 0.17 11.2 0.0 4.8 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_29 PF13555.1 KFP05641.1 - 0.0001 21.7 0.0 2 8.0 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFP05641.1 - 0.00014 22.2 3.3 3.3 8.0 0.0 5.3 4 0 0 4 4 3 2 ABC transporter RNA_helicase PF00910.17 KFP05641.1 - 0.0017 18.5 0.0 12 6.1 0.0 5.1 5 0 0 5 5 5 0 RNA helicase Phlebovirus_NSM PF07246.6 KFP05641.1 - 0.0022 17.2 2.1 0.0022 17.2 1.4 2.7 2 0 0 2 2 1 1 Phlebovirus nonstructural protein NS-M AAA_25 PF13481.1 KFP05641.1 - 0.0093 15.3 0.0 0.76 9.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KFP05641.1 - 0.0097 15.3 4.5 4 6.7 0.0 5.1 5 0 0 5 5 5 1 AAA-like domain B56 PF01603.15 KFP05642.1 - 3.5e-177 589.1 11.7 4.3e-177 588.8 8.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) T4_deiodinase PF00837.12 KFP05643.1 - 9.8e-61 204.7 0.0 1.1e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase T4_deiodinase PF00837.12 KFP05644.1 - 1e-41 142.5 0.0 1.2e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase EGF PF00008.22 KFP05646.1 - 2.7e-31 107.1 90.5 9.9e-09 35.0 7.1 6.7 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.2 KFP05646.1 - 4.5e-14 51.4 47.3 0.001 18.9 0.6 7.4 6 0 0 6 6 6 6 Human growth factor-like EGF EGF_2 PF07974.8 KFP05646.1 - 5.6e-10 39.2 102.3 0.0059 16.7 6.3 6.4 6 0 0 6 6 6 6 EGF-like domain Laminin_EGF PF00053.19 KFP05646.1 - 0.039 13.8 71.2 0.16 11.9 5.7 6.5 3 2 3 6 6 6 0 Laminin EGF-like (Domains III and V) EGF_CA PF07645.10 KFP05646.1 - 3.5 7.7 81.9 0.22 11.5 6.7 6.7 4 1 2 6 6 6 0 Calcium-binding EGF domain Yae1_N PF09811.4 KFP05647.1 - 9.2e-15 53.8 48.9 1.5e+04 -9.7 33.9 4.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ribosomal_S4e PF00900.15 KFP05648.1 - 1.7e-32 110.9 0.7 2.7e-32 110.2 0.5 1.3 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KFP05648.1 - 3.9e-21 74.5 3.1 8.7e-21 73.4 2.2 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 KFP05648.1 - 7.2e-06 25.5 0.6 4.3e-05 23.0 0.1 2.6 2 1 0 2 2 2 1 KOW motif S4 PF01479.20 KFP05648.1 - 1.5e-05 24.3 0.0 2.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain Glyco_hydro_15 PF00723.16 KFP05649.1 - 2.1e-152 507.8 0.0 2.6e-152 507.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 TGF_beta PF00019.15 KFP05650.1 - 2.6e-28 98.3 0.1 4.4e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP05650.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 TGF-beta propeptide PDZ_assoc PF10600.4 KFP05650.1 - 0.078 13.2 0.5 0.62 10.3 0.1 2.6 3 0 0 3 3 3 0 PDZ-associated domain of NMDA receptors ASD2 PF08687.6 KFP05652.1 - 7e-56 189.4 7.2 7.7e-56 189.3 5.0 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Cyclin_N PF00134.18 KFP05653.1 - 1.4e-05 24.6 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Gal_Lectin PF02140.13 KFP05654.1 - 1e-36 125.1 8.1 8e-18 64.5 0.9 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain FAM176 PF14851.1 KFP05654.1 - 1.7e-07 31.0 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 FAM176 family DUF3395 PF11875.3 KFP05654.1 - 0.17 11.5 0.1 9.5 5.8 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3395) Dickkopf_N PF04706.7 KFP05654.1 - 0.63 10.2 6.7 1.2 9.3 0.8 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region GST_N_3 PF13417.1 KFP05655.1 - 9.2e-07 28.9 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFP05655.1 - 7.3e-06 25.8 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFP05655.1 - 1.6e-05 24.7 0.0 3e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KFP05655.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF1533 PF07550.6 KFP05655.1 - 0.023 14.7 0.1 0.054 13.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1533) GST_C_3 PF14497.1 KFP05655.1 - 0.039 14.4 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFP05655.1 - 0.061 13.3 0.0 0.2 11.6 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidase PF01425.16 KFP05657.1 - 4.9e-81 272.8 0.0 8e-81 272.1 0.0 1.3 1 1 0 1 1 1 1 Amidase TSC22 PF01166.13 KFP05658.1 - 2e-30 104.5 5.8 2e-30 104.5 4.1 2.0 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF972 PF06156.8 KFP05658.1 - 0.00068 19.9 1.1 0.00068 19.9 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF972) DivIC PF04977.10 KFP05658.1 - 0.00086 18.7 3.6 0.0045 16.4 1.7 2.2 2 0 0 2 2 2 1 Septum formation initiator MAD PF05557.8 KFP05658.1 - 0.0038 15.3 3.1 0.0096 14.0 2.2 1.5 2 0 0 2 2 2 1 Mitotic checkpoint protein DUF904 PF06005.7 KFP05658.1 - 0.0097 16.1 8.3 0.0097 16.1 5.8 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF904) DUF16 PF01519.11 KFP05658.1 - 0.016 15.3 1.1 0.029 14.6 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF2216 PF10226.4 KFP05658.1 - 0.038 13.4 0.9 0.23 10.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) DUF948 PF06103.6 KFP05658.1 - 0.053 13.3 0.3 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) bZIP_2 PF07716.10 KFP05658.1 - 0.069 12.9 5.2 0.16 11.8 3.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF3371 PF11851.3 KFP05658.1 - 0.1 13.2 1.0 1.4 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF1895 PF08988.5 KFP05658.1 - 0.18 11.8 1.0 0.49 10.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1895) Fzo_mitofusin PF04799.8 KFP05658.1 - 0.25 10.7 2.6 0.15 11.4 0.6 1.5 2 0 0 2 2 2 0 fzo-like conserved region IncA PF04156.9 KFP05658.1 - 2.3 7.7 7.5 2.7 7.5 4.7 1.4 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 KFP05658.1 - 4.7 7.2 8.1 1.5 8.8 3.7 1.7 2 0 0 2 2 2 0 bZIP transcription factor SPRY PF00622.23 KFP05660.1 - 8.4e-16 58.1 0.1 1.5e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.19 KFP05660.1 - 3.1e-09 36.5 12.2 2.2e-08 33.8 0.6 4.5 6 0 0 6 6 6 2 B-box zinc finger zf-C3HC4_3 PF13920.1 KFP05660.1 - 3.2e-08 33.1 5.9 3.2e-08 33.1 4.1 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP05660.1 - 1.4e-07 31.3 10.2 1.4e-07 31.3 7.1 3.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) fn3 PF00041.16 KFP05660.1 - 5.4e-07 29.6 0.2 1e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4 PF00097.20 KFP05660.1 - 7.4e-07 28.7 8.9 7.4e-07 28.7 6.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP05660.1 - 1.7e-06 27.7 11.4 1.7e-06 27.7 7.9 3.9 5 0 0 5 5 5 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFP05660.1 - 2.6e-06 27.1 9.8 2.6e-06 27.1 6.8 3.0 2 1 0 2 2 2 1 Ring finger domain PRY PF13765.1 KFP05660.1 - 3.6e-06 26.4 0.0 1.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 SPRY-associated domain zf-RING_UBOX PF13445.1 KFP05660.1 - 5.4e-05 22.8 6.2 0.00022 20.8 4.3 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFP05660.1 - 7.4e-05 22.3 8.0 7.4e-05 22.3 5.5 3.7 4 0 0 4 4 4 1 zinc-RING finger domain FAD-oxidase_C PF02913.14 KFP05660.1 - 0.1 11.8 0.3 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain zf-H2C2_2 PF13465.1 KFP05660.1 - 2.5 8.5 6.6 33 5.0 0.0 4.6 4 0 0 4 4 4 0 Zinc-finger double domain SNF2_N PF00176.18 KFP05661.1 - 8.2e-59 198.8 0.0 2.1e-58 197.4 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFP05661.1 - 2.4e-15 56.1 0.4 9.5e-14 51.0 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP05661.1 - 3e-10 40.2 0.0 9.1e-10 38.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFP05661.1 - 2.1e-07 30.6 0.0 6.3e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KFP05661.1 - 7.5e-06 24.9 0.0 1.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.1 KFP05661.1 - 0.0022 16.8 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD_2 PF06733.10 KFP05661.1 - 0.017 14.4 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 TK PF00265.13 KFP05661.1 - 0.17 11.4 1.2 16 5.0 0.1 2.6 3 0 0 3 3 3 0 Thymidine kinase Exo_endo_phos PF03372.18 KFP05662.1 - 2.6e-32 112.7 0.0 4.3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 KFP05662.1 - 1e-25 90.1 0.1 1.8e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Sigma70_r1_1 PF03979.9 KFP05662.1 - 0.068 13.1 0.1 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Creatinase_N PF01321.13 KFP05663.1 - 4.7e-17 62.7 0.0 4.3e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.19 KFP05664.1 - 4.5e-33 114.5 0.0 5.3e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 URO-D PF01208.12 KFP05664.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) SAM_1 PF00536.25 KFP05665.1 - 5.2e-09 36.1 0.2 7.8e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP05665.1 - 5.4e-09 35.7 0.7 7.9e-09 35.2 0.5 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 KFP05665.1 - 1.5e-06 27.5 0.0 2.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SLY PF12485.3 KFP05665.1 - 1.9e-06 28.1 0.4 4e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Lymphocyte signaling adaptor protein SH3_1 PF00018.23 KFP05665.1 - 0.0054 16.0 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP05665.1 - 0.058 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain zf-DHHC PF01529.15 KFP05666.1 - 1.3e-40 138.6 3.4 1.3e-40 138.6 2.3 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase UPF0182 PF03699.8 KFP05666.1 - 0.025 12.5 0.1 0.025 12.5 0.0 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) DUF4131 PF13567.1 KFP05666.1 - 0.22 10.9 8.8 0.22 10.9 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Utp14 PF04615.8 KFP05667.1 - 8e-158 526.8 28.5 7e-90 302.2 14.8 2.2 1 1 0 2 2 2 2 Utp14 protein Ank_2 PF12796.2 KFP05668.1 - 1.6e-17 63.6 0.1 1.6e-11 44.3 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP05668.1 - 8.1e-16 56.9 1.6 7.6e-07 28.6 0.3 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFP05668.1 - 2.2e-14 52.1 1.0 5.5e-06 26.1 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFP05668.1 - 9e-12 45.1 2.6 3.1e-08 33.8 0.3 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP05668.1 - 1.8e-09 37.5 5.2 0.00044 20.3 0.4 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AIF_C PF14721.1 KFP05669.1 - 2.3e-60 202.6 0.0 3.4e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.9 KFP05669.1 - 5.5e-24 85.1 0.0 1.6e-23 83.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFP05669.1 - 7.9e-13 48.6 0.3 3.3e-11 43.4 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AIF-MLS PF14962.1 KFP05669.1 - 7.3e-12 45.3 0.0 7.3e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Mitochondria Localisation Sequence DAO PF01266.19 KFP05669.1 - 9.2e-07 28.0 8.1 0.00025 20.0 0.0 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFP05669.1 - 3.9e-06 27.0 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFP05669.1 - 1.2e-05 25.1 3.9 0.33 10.7 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFP05669.1 - 0.0013 17.7 0.7 0.22 10.4 0.0 3.0 2 1 1 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 KFP05669.1 - 0.0036 15.8 0.7 0.51 8.7 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 KFP05669.1 - 0.0065 15.4 0.0 0.086 11.7 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 KFP05669.1 - 0.019 14.0 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KFP05669.1 - 0.021 13.8 0.6 0.62 9.0 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFP05669.1 - 0.054 13.5 3.0 4.4 7.4 0.1 3.1 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Reductase_C PF14759.1 KFP05669.1 - 0.095 13.0 0.0 0.4 11.0 0.0 2.0 1 0 0 1 1 1 0 Reductase C-terminal PYNP_C PF07831.8 KFP05669.1 - 0.098 12.1 0.1 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Ribosomal_S4e PF00900.15 KFP05669.1 - 0.13 11.9 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal family S4e Trp_halogenase PF04820.9 KFP05669.1 - 0.13 10.8 0.2 31 3.0 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase tRNA-synt_1g PF09334.6 KFP05670.1 - 2.8e-76 256.7 0.0 3.7e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFP05670.1 - 9.5e-13 47.0 0.0 2e-10 39.3 0.0 2.7 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFP05670.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFP05670.1 - 0.00024 20.3 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.17 KFP05671.1 - 1.3e-15 56.8 0.1 1.9e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP05671.1 - 1.2e-11 44.2 0.2 1.8e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05671.1 - 2.2e-09 37.1 0.0 3.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFP05671.1 - 0.0059 16.3 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 KFP05672.1 - 3.4e-40 135.6 0.1 9.2e-21 73.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein ThiW PF09512.5 KFP05672.1 - 0.13 12.0 2.4 0.25 11.1 1.6 1.5 1 1 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) RRM_1 PF00076.17 KFP05673.1 - 7.7e-08 31.8 0.0 1.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05673.1 - 1.7e-05 24.6 0.0 3.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFP05673.1 - 0.0098 15.6 0.1 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KFP05673.1 - 0.06 13.2 0.1 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF464 PF04327.7 KFP05673.1 - 3.7 7.8 5.6 25 5.1 1.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF464) RhoGAP PF00620.22 KFP05674.1 - 1e-39 135.5 0.7 3.3e-29 101.4 0.0 2.5 3 0 0 3 3 3 2 RhoGAP domain RGCC PF15151.1 KFP05675.1 - 3.1e-40 137.3 0.1 3.3e-40 137.2 0.1 1.0 1 0 0 1 1 1 1 Response gene to complement 32 protein family DUF465 PF04325.8 KFP05675.1 - 0.054 13.2 0.2 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Pheromone PF08015.6 KFP05675.1 - 2.4 9.0 4.8 2.4 9.0 0.1 2.3 2 1 0 2 2 2 0 Fungal mating-type pheromone Voltage_CLC PF00654.15 KFP05676.1 - 1.9e-93 313.3 20.5 1.9e-93 313.3 14.2 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFP05676.1 - 4.3e-16 58.4 2.0 2e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain TNF PF00229.13 KFP05677.1 - 1.5e-35 121.5 0.1 2.2e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family I-set PF07679.11 KFP05678.1 - 1.3e-13 50.6 0.0 1.8e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain V-set PF07686.12 KFP05678.1 - 2.4e-11 43.5 0.1 9.1e-07 28.7 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP05678.1 - 5.2e-10 39.6 0.2 3.8e-07 30.5 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.1 KFP05678.1 - 5.3e-10 39.2 0.2 9.2e-08 32.1 0.1 2.2 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP05678.1 - 1e-06 28.7 0.1 0.00068 19.7 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin domain TauD PF02668.11 KFP05679.1 - 3.4e-37 128.5 0.3 4.8e-37 128.0 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KFP05679.1 - 2.2e-05 24.7 0.0 4.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 KFP05679.1 - 0.0036 16.2 0.0 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 CsiD Pou PF00157.12 KFP05680.1 - 1.3e-31 108.1 0.0 2.2e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFP05680.1 - 7.5e-18 63.8 1.7 1.8e-17 62.7 1.2 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 KFP05680.1 - 0.00025 21.1 0.2 0.0094 16.1 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.2 KFP05680.1 - 0.00083 19.3 0.0 0.049 13.6 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.6 KFP05680.1 - 0.027 14.1 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Lsr2 PF11774.3 KFP05680.1 - 0.12 12.2 0.2 0.2 11.6 0.1 1.4 1 1 0 1 1 1 0 Lsr2 7tm_1 PF00001.16 KFP05682.1 - 2.3e-31 108.8 11.4 7.8e-31 107.1 7.9 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05682.1 - 2.5e-05 23.5 9.8 0.00084 18.5 0.3 3.2 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFP05682.1 - 0.0059 15.7 9.1 0.0095 15.0 1.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw RNA_pol_L_2 PF13656.1 KFP05683.1 - 2.6e-26 90.8 0.0 3.1e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFP05683.1 - 2.1e-07 29.9 0.0 3.1e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Longin PF13774.1 KFP05684.1 - 1.3e-28 98.3 0.6 2.2e-28 97.6 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFP05684.1 - 2.6e-28 97.4 2.8 4e-28 96.8 1.9 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF3753 PF12575.3 KFP05684.1 - 1.3 8.8 10.2 2.2 8.1 2.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) SLAIN PF15301.1 KFP05685.1 - 1.7e-109 366.4 39.4 2e-109 366.1 27.3 1.1 1 0 0 1 1 1 1 SLAIN motif-containing family DUF4095 PF13338.1 KFP05685.1 - 0.0086 16.2 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4095) LIM PF00412.17 KFP05686.1 - 0.002 18.1 14.5 0.003 17.5 10.1 1.3 1 0 0 1 1 1 1 LIM domain Endonuclease_7 PF02945.10 KFP05686.1 - 1.8 8.3 9.3 2.7 7.7 6.5 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII 3Beta_HSD PF01073.14 KFP05687.1 - 1.4e-69 233.8 0.0 1.8e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFP05687.1 - 7e-38 130.3 0.0 9e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFP05687.1 - 1.1e-15 57.3 0.0 1.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFP05687.1 - 5.5e-15 55.8 0.0 8.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFP05687.1 - 1.2e-11 43.9 0.0 3.8e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.8 KFP05687.1 - 2.3e-07 30.3 0.0 3.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KFP05687.1 - 4.6e-07 29.0 0.0 3.5e-06 26.1 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFP05687.1 - 0.001 19.0 0.1 1.2 9.0 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase NAD_binding_2 PF03446.10 KFP05687.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 KFP05687.1 - 0.088 12.4 0.1 3.7 7.1 0.0 2.2 1 1 1 2 2 2 0 KR domain EF-hand_1 PF00036.27 KFP05688.1 - 8.3e-31 102.9 16.6 9.8e-09 33.9 0.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFP05688.1 - 2.5e-27 94.7 9.2 1.5e-14 53.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP05688.1 - 3.9e-25 87.2 15.7 1.5e-12 46.9 0.6 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFP05688.1 - 3.2e-24 82.5 10.3 6.1e-08 31.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFP05688.1 - 9.8e-18 62.6 16.9 2.5e-05 23.4 0.1 4.6 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 KFP05688.1 - 8e-16 57.7 0.2 1e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFP05688.1 - 1.4e-06 27.9 6.3 0.092 12.4 0.7 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 KFP05688.1 - 0.004 15.5 0.5 0.016 13.5 0.2 1.8 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) SPARC_Ca_bdg PF10591.4 KFP05688.1 - 0.0077 16.2 1.5 2.3 8.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SRI PF08236.6 KFP05688.1 - 0.042 13.8 3.6 0.18 11.7 0.2 2.7 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DUF4373 PF14297.1 KFP05688.1 - 0.072 13.3 3.5 3.5 8.0 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4373) DUF21 PF01595.15 KFP05688.1 - 0.074 12.3 1.8 0.74 9.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF4601 PF15373.1 KFP05688.1 - 0.089 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) Toprim_2 PF13155.1 KFP05688.1 - 0.13 12.6 2.7 6.9 7.0 0.5 2.3 1 1 1 2 2 2 0 Toprim-like TBPIP PF07106.8 KFP05688.1 - 0.27 10.7 5.2 1.3 8.5 0.6 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF892 PF05974.7 KFP05688.1 - 0.46 10.2 3.1 1.4 8.7 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF892) MgtE_N PF03448.12 KFP05688.1 - 0.68 10.2 4.2 0.36 11.1 0.5 2.2 3 0 0 3 3 2 0 MgtE intracellular N domain DUF217 PF02697.9 KFP05688.1 - 4.2 7.7 9.3 1.1 9.5 1.4 3.1 1 1 3 4 4 4 0 Uncharacterized ACR, COG1753 DJ-1_PfpI PF01965.19 KFP05689.1 - 9.7e-14 51.0 0.1 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Sua5_yciO_yrdC PF01300.13 KFP05690.1 - 2.7e-33 114.7 0.0 3.8e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Grp1_Fun34_YaaH PF01184.14 KFP05690.1 - 0.00012 21.4 16.9 0.00012 21.4 11.7 4.5 3 1 2 5 5 5 1 GPR1/FUN34/yaaH family MmgE_PrpD PF03972.9 KFP05691.1 - 4e-57 193.3 0.0 5e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF927 PF06048.6 KFP05691.1 - 0.18 11.0 0.3 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF927) Glyoxalase_2 PF12681.2 KFP05692.1 - 5.7e-13 49.4 0.0 6.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFP05692.1 - 1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFP05692.1 - 0.013 15.4 0.0 0.043 13.7 0.0 1.8 1 1 1 2 2 2 0 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFP05692.1 - 0.019 14.9 0.0 0.06 13.3 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 KFP05692.1 - 0.086 12.5 0.0 0.97 9.1 0.0 2.0 2 0 0 2 2 2 0 CppA N-terminal zf-C2H2 PF00096.21 KFP05694.1 - 1.4e-13 50.2 24.9 0.00011 22.2 3.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP05694.1 - 4e-10 39.4 24.9 9.6e-06 25.6 0.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP05694.1 - 1.2e-08 34.7 22.9 0.0071 16.6 0.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP05694.1 - 0.83 9.8 8.8 4 7.6 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RPAP2_Rtr1 PF04181.8 KFP05694.1 - 1.3 9.1 4.2 3.9 7.6 2.9 1.8 1 1 0 1 1 1 0 Rtr1/RPAP2 family zf-H2C2_2 PF13465.1 KFP05695.1 - 1.2e-10 41.1 11.2 3.7e-05 23.7 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP05695.1 - 1.6e-08 34.3 10.8 0.00056 20.1 0.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP05695.1 - 3e-05 24.0 10.9 0.0096 16.1 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP05695.1 - 0.66 10.3 0.1 0.66 10.3 0.0 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Gtr1_RagA PF04670.7 KFP05696.1 - 2.4e-108 360.6 1.0 3.1e-108 360.2 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KFP05696.1 - 7.7e-09 35.1 0.0 1.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFP05696.1 - 1.8e-08 33.8 0.1 3.1e-08 33.0 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP05696.1 - 9.1e-06 25.6 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFP05696.1 - 3.7e-05 24.2 0.1 0.00013 22.4 0.0 2.0 2 1 1 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 KFP05696.1 - 0.0019 17.6 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP05696.1 - 0.0042 16.3 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFP05696.1 - 0.014 14.9 0.2 0.06 12.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 KFP05696.1 - 0.022 13.6 1.7 0.23 10.3 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFP05696.1 - 0.023 15.0 0.2 0.044 14.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KFP05696.1 - 0.035 13.6 0.3 0.063 12.8 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 KFP05696.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF4606 PF15379.1 KFP05697.1 - 5.1e-38 129.3 1.0 5.6e-38 129.1 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4606) Myotub-related PF06602.9 KFP05698.1 - 2e-143 477.4 0.0 2.5e-143 477.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KFP05698.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Vps36_ESCRT-II PF11605.3 KFP05698.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Y_phosphatase2 PF03162.8 KFP05698.1 - 0.0021 17.4 0.1 0.13 11.6 0.1 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KFP05698.1 - 0.0022 18.2 0.1 0.0063 16.7 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KFP05698.1 - 0.0038 16.8 0.1 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain WTX PF09422.5 KFP05699.1 - 1.9e-59 201.8 24.5 1.9e-22 79.9 4.1 3.0 2 1 1 3 3 3 3 WTX protein RhoGEF PF00621.15 KFP05701.1 - 2.1e-46 158.0 2.8 2.1e-46 158.0 2.0 1.8 2 1 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KFP05701.1 - 1.4e-12 46.9 0.2 3e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP05701.1 - 2.2e-10 39.7 1.8 4.8e-10 38.6 1.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP05701.1 - 1.3e-09 37.3 0.1 3.4e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFP05701.1 - 2.5e-06 27.6 0.3 5.4e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 PH domain CSD PF00313.17 KFP05701.1 - 0.057 13.2 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain SH3_3 PF08239.6 KFP05701.1 - 0.086 13.0 0.3 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Pkinase_Tyr PF07714.12 KFP05702.1 - 3.5e-102 340.9 0.0 5.2e-102 340.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP05702.1 - 3.1e-45 154.3 0.0 4.5e-31 107.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain I-set PF07679.11 KFP05702.1 - 1.1e-33 114.9 1.6 5.1e-19 67.9 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05702.1 - 1.9e-23 82.3 4.2 4.9e-10 39.4 0.0 3.3 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFP05702.1 - 1.5e-20 73.4 6.0 4.3e-09 36.7 0.0 3.7 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.20 KFP05702.1 - 1e-13 51.1 2.4 7.5e-06 25.9 0.1 3.9 4 1 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 KFP05702.1 - 4.8e-11 42.5 7.5 4.2e-06 26.6 1.1 4.4 3 2 0 3 3 3 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP05702.1 - 0.0009 19.1 0.2 0.01 15.6 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP05702.1 - 0.002 16.4 0.2 1.1 7.4 0.0 2.7 1 1 0 2 2 2 2 Alphaherpesvirus glycoprotein E FAM176 PF14851.1 KFP05702.1 - 0.097 12.3 0.2 4.1 7.0 0.0 2.7 3 0 0 3 3 3 0 FAM176 family Caudal_act PF04731.7 KFP05703.1 - 9.3e-51 171.7 13.9 1.2e-50 171.4 9.6 1.1 1 0 0 1 1 1 1 Caudal like protein activation region Homeobox PF00046.24 KFP05703.1 - 1.8e-20 72.3 5.8 2.7e-20 71.7 4.0 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP05703.1 - 0.042 13.5 0.9 0.082 12.6 0.6 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 KFP05703.1 - 0.071 12.1 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Caudal_act PF04731.7 KFP05704.1 - 3.1e-48 163.5 12.8 4.1e-48 163.1 8.8 1.1 1 0 0 1 1 1 1 Caudal like protein activation region Homeobox PF00046.24 KFP05704.1 - 6.2e-22 76.9 3.0 9.4e-22 76.3 2.1 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP05704.1 - 0.017 14.7 0.6 0.038 13.6 0.4 1.6 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 KFP05704.1 - 0.093 11.8 0.1 0.2 10.7 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Erf4 PF10256.4 KFP05705.1 - 5.4e-26 90.7 0.1 6.1e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Fip1 PF05182.8 KFP05706.1 - 1e-26 91.8 0.7 1.6e-26 91.3 0.5 1.3 1 0 0 1 1 1 1 Fip1 motif PDZ PF00595.19 KFP05708.1 - 7e-64 211.9 3.8 2.1e-16 59.8 0.1 4.2 4 0 0 4 4 4 4 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP05708.1 - 2.6e-23 81.6 0.7 0.00021 21.1 0.0 4.3 4 0 0 4 4 4 4 PDZ domain zf-C3HC4 PF00097.20 KFP05708.1 - 2.3e-07 30.3 8.6 5.6e-07 29.1 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP05708.1 - 3.1e-06 27.1 7.2 1e-05 25.4 5.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tricorn_PDZ PF14685.1 KFP05708.1 - 3.2e-06 26.8 0.1 5.5 6.8 0.0 4.4 4 0 0 4 4 4 2 Tricorn protease PDZ domain zf-RING_2 PF13639.1 KFP05708.1 - 4.4e-06 26.4 7.4 4.4e-06 26.4 5.1 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 KFP05708.1 - 7.8e-06 25.5 6.5 2.3e-05 23.9 4.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP05708.1 - 1.5e-05 24.7 9.5 5e-05 23.0 6.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFP05708.1 - 2.7e-05 23.7 6.4 7.1e-05 22.4 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFP05708.1 - 5.6e-05 22.7 3.9 5.6e-05 22.7 2.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KFP05708.1 - 0.00082 19.2 0.3 0.021 14.7 0.0 2.8 1 1 1 2 2 2 1 U-box domain zf-TRAF PF02176.13 KFP05708.1 - 0.0045 17.3 1.3 0.013 15.8 0.9 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger SR-25 PF10500.4 KFP05708.1 - 0.011 15.2 4.0 0.025 14.0 2.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.8 KFP05708.1 - 0.072 12.4 1.5 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal zf-rbx1 PF12678.2 KFP05708.1 - 0.57 10.3 9.9 0.07 13.2 3.2 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger Ras PF00071.17 KFP05709.1 - 4.3e-23 81.4 0.0 1.8e-22 79.4 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFP05709.1 - 1.7e-09 38.1 0.0 3.6e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFP05709.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family UCH PF00443.24 KFP05710.1 - 9.2e-68 228.2 4.6 1.1e-67 228.0 3.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP05710.1 - 1.9e-38 132.6 2.8 2.2e-38 132.3 2.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KFP05710.1 - 0.027 13.7 10.8 0.87 8.8 6.3 2.9 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3510 PF12022.3 KFP05710.1 - 0.048 13.7 0.5 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) NapB PF03892.9 KFP05710.1 - 0.31 10.7 2.8 0.79 9.3 2.0 1.7 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) 7tm_1 PF00001.16 KFP05711.1 - 1e-31 110.0 12.9 1.2e-31 109.8 8.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.11 KFP05712.1 - 9.3e-22 77.2 33.0 1.2e-11 43.9 9.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.1 KFP05713.1 - 5.1e-15 55.0 7.5 8.1e-15 54.3 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP05713.1 - 1.5e-09 37.8 2.6 2.8e-09 36.9 1.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP05713.1 - 1.6e-06 27.6 7.6 2.6e-06 26.9 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP05713.1 - 8.9e-06 25.2 4.2 1.3e-05 24.7 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP05713.1 - 1.3e-05 24.7 6.4 2.1e-05 24.1 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFP05713.1 - 3.8e-05 23.4 1.4 7.9e-05 22.4 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KFP05713.1 - 6.7e-05 22.8 7.5 0.00011 22.1 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFP05713.1 - 0.048 13.2 4.4 0.086 12.4 3.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KFP05713.1 - 0.055 13.0 2.2 0.1 12.1 1.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 KFP05713.1 - 1.1 9.2 7.0 1.9 8.5 4.8 1.3 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 KFP05713.1 - 1.2 9.2 7.5 2.2 8.3 5.2 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFP05713.1 - 1.8 8.5 5.2 6.3 6.8 3.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Ndc1_Nup PF09531.5 KFP05714.1 - 2 6.7 5.4 5.3 5.3 3.7 1.7 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_tran PF00005.22 KFP05716.1 - 2.1e-34 118.7 0.0 4.2e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KFP05716.1 - 9.8e-29 100.6 9.0 1.2e-28 100.2 6.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KFP05716.1 - 1.3e-06 27.8 0.0 0.00059 19.1 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFP05716.1 - 2.8e-05 24.1 0.2 0.0038 17.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KFP05716.1 - 0.00013 22.0 0.7 0.18 11.7 0.1 3.0 2 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KFP05716.1 - 0.00026 20.4 0.2 0.00082 18.8 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KFP05716.1 - 0.0018 19.1 0.1 0.0063 17.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KFP05716.1 - 0.0074 16.2 0.0 0.038 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KFP05716.1 - 0.0076 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KFP05716.1 - 0.0076 16.3 0.1 0.088 12.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFP05716.1 - 0.022 14.6 0.3 0.063 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFP05716.1 - 0.024 14.9 0.0 0.081 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFP05716.1 - 0.03 13.7 0.1 0.062 12.7 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 KFP05716.1 - 0.045 12.9 0.0 0.14 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KFP05716.1 - 0.047 13.1 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 KFP05716.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_ab PF00006.20 KFP05716.1 - 0.087 12.3 0.1 0.16 11.4 0.1 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 KFP05716.1 - 0.096 13.1 0.1 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein UPRTase PF14681.1 KFP05717.1 - 2.5e-36 124.8 0.0 1.7e-29 102.5 0.0 2.1 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFP05717.1 - 3.1e-05 23.7 0.0 4.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 14-3-3 PF00244.15 KFP05717.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein zf-DHHC PF01529.15 KFP05718.1 - 1.1e-40 138.9 13.1 1.1e-40 138.9 9.1 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 KFP05718.1 - 0.089 12.1 4.3 0.12 11.7 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pex24p PF06398.6 KFP05718.1 - 0.67 8.6 6.2 4.4 6.0 4.5 1.8 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Spt4 PF06093.8 KFP05718.1 - 3 7.7 8.2 3.9 7.4 4.8 1.8 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger FGF PF00167.13 KFP05719.1 - 5.5e-32 110.0 0.1 6.3e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor SIR2 PF02146.12 KFP05719.1 - 0.1 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Sir2 family SNF2_N PF00176.18 KFP05720.1 - 5.7e-63 212.4 0.0 5.7e-63 212.4 0.0 2.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFP05720.1 - 1.1e-14 53.9 0.0 5.1e-14 51.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OST3_OST6 PF04756.8 KFP05721.1 - 1.1e-50 171.3 0.0 1.7e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KFP05721.1 - 1.6e-05 24.4 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4131 PF13567.1 KFP05721.1 - 0.046 13.1 3.6 0.1 11.9 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) COX7B PF05392.6 KFP05722.1 - 6.6e-34 115.3 0.0 7.2e-34 115.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB HMA PF00403.21 KFP05723.1 - 4.9e-79 260.4 12.0 2e-12 47.0 0.1 7.4 7 0 0 7 7 7 6 Heavy-metal-associated domain Hydrolase PF00702.21 KFP05723.1 - 6.2e-74 249.0 1.1 3e-73 246.8 0.3 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFP05723.1 - 4.1e-48 163.4 1.5 4.1e-48 163.4 1.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KFP05723.1 - 4e-14 53.2 0.0 1.3e-13 51.5 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_3 PF08777.6 KFP05723.1 - 1.8e-06 27.7 0.0 1.5 8.7 0.0 4.9 5 0 0 5 5 5 2 RNA binding motif Hydrolase_3 PF08282.7 KFP05723.1 - 6.3e-06 25.9 2.5 0.00068 19.2 1.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KFP05723.1 - 0.0025 17.6 0.1 0.016 15.0 0.0 2.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2997 PF11211.3 KFP05723.1 - 5.1 6.5 10.3 2.6 7.4 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2997) I-set PF07679.11 KFP05724.1 - 8.1e-11 41.6 0.2 4.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05724.1 - 2.8e-10 40.1 0.2 1.4e-05 25.0 0.0 2.2 1 1 1 2 2 2 2 Immunoglobulin domain V-set PF07686.12 KFP05724.1 - 2.8e-08 33.6 2.5 5.2e-06 26.3 0.1 3.1 1 1 1 2 2 2 1 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP05724.1 - 3.9e-08 33.6 1.7 0.0031 17.9 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP05724.1 - 1.5e-07 31.4 3.5 0.00032 20.7 0.4 3.1 2 1 0 2 2 2 2 Immunoglobulin domain V-set_CD47 PF08204.6 KFP05724.1 - 0.0049 16.6 0.5 0.11 12.2 0.3 2.7 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Herpes_gE PF02480.11 KFP05724.1 - 0.034 12.4 0.0 0.057 11.6 0.0 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF616 PF04765.8 KFP05724.1 - 0.067 12.3 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF616) YcgR_2 PF12945.2 KFP05724.1 - 0.082 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein YcgR PARP PF00644.15 KFP05725.1 - 3.8e-14 52.6 0.3 8.7e-14 51.4 0.2 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain LIM PF00412.17 KFP05726.1 - 1.1e-22 79.8 16.1 6.8e-15 54.8 7.1 2.3 2 0 0 2 2 2 2 LIM domain Homeobox PF00046.24 KFP05726.1 - 5e-15 54.8 0.2 8.2e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP05726.1 - 0.0014 18.3 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain eRF1_1 PF03463.10 KFP05727.1 - 7.6e-47 158.1 0.1 1.3e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KFP05727.1 - 3.1e-35 121.3 0.0 5e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KFP05727.1 - 1e-26 93.4 0.1 2.9e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 MethyTransf_Reg PF10119.4 KFP05727.1 - 0.0085 16.5 0.1 0.11 12.9 0.0 2.5 1 1 1 2 2 2 1 Predicted methyltransferase regulatory domain Integrin_alpha2 PF08441.7 KFP05728.1 - 6.8e-81 272.4 12.5 9.6e-81 271.9 8.7 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.23 KFP05728.1 - 5.7e-41 140.1 0.6 1.3e-40 139.0 0.4 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.18 KFP05728.1 - 8.9e-14 50.7 10.0 3.4e-06 26.5 0.6 3.6 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.1 KFP05728.1 - 1.2e-10 41.8 0.2 2.1e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.1 KFP05728.1 - 2.6e-06 27.7 4.0 0.016 15.5 0.1 4.0 4 0 0 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 KFP05728.1 - 1.4e-05 25.0 1.8 0.27 11.2 0.1 4.5 4 0 0 4 4 4 1 FG-GAP repeat Ferritin PF00210.19 KFP05728.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain Integrin_alpha PF00357.15 KFP05728.1 - 0.14 11.9 4.3 0.32 10.8 3.0 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Kazal_2 PF07648.10 KFP05729.1 - 1e-34 118.1 31.5 1.1e-13 50.7 1.1 4.9 4 1 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP05729.1 - 6e-25 87.0 38.9 8.5e-10 38.5 5.3 4.1 3 1 0 3 3 3 3 Kazal-type serine protease inhibitor domain FOLN PF09289.5 KFP05729.1 - 1.2e-08 34.6 15.2 1.2e-08 34.6 10.5 4.8 5 1 0 5 5 5 2 Follistatin/Osteonectin-like EGF domain ETC_C1_NDUFA4 PF04800.7 KFP05730.1 - 2.3e-32 110.8 0.3 3.5e-32 110.2 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.4 KFP05730.1 - 0.011 15.6 0.0 0.03 14.2 0.0 1.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Arf PF00025.16 KFP05731.1 - 7.3e-30 103.4 0.0 8.6e-30 103.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KFP05731.1 - 3.7e-08 33.8 0.0 4.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KFP05731.1 - 3.7e-07 29.6 0.0 4.2e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP05731.1 - 4e-07 29.4 0.0 4.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFP05731.1 - 1.1e-05 24.6 0.0 1.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP05731.1 - 4.1e-05 23.5 0.0 9.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFP05731.1 - 0.00089 18.0 1.0 0.026 13.2 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 KFP05731.1 - 0.0015 18.6 0.0 0.0023 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFP05731.1 - 0.0017 18.5 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFP05731.1 - 0.0032 17.3 0.0 0.0045 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP05731.1 - 0.0048 16.9 0.4 0.011 15.7 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KFP05731.1 - 0.01 15.5 0.0 0.16 11.5 0.0 2.1 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KFP05731.1 - 0.011 16.0 0.4 0.088 13.1 0.3 2.0 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 KFP05731.1 - 0.018 14.5 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KFP05731.1 - 0.031 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFP05731.1 - 0.037 14.8 0.0 0.044 14.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFP05731.1 - 0.046 13.8 0.1 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 RNA helicase PduV-EutP PF10662.4 KFP05731.1 - 0.058 12.8 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KFP05731.1 - 0.059 12.9 0.0 3.4 7.1 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KFP05731.1 - 0.12 11.6 0.2 0.2 10.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 HSP20 PF00011.16 KFP05732.1 - 1.5e-14 53.6 0.0 2.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BAR_3_WASP_bdg PF10456.4 KFP05733.1 - 1.9e-113 377.5 6.2 2.8e-113 377.0 4.3 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.19 KFP05733.1 - 9.2e-23 80.1 0.6 1.9e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KFP05733.1 - 0.0051 16.1 2.8 0.0051 16.1 2.0 2.2 2 0 0 2 2 2 1 Vps5 C terminal like IGFBP PF00219.13 KFP05734.1 - 2.1e-05 24.9 20.9 2.1e-05 24.9 14.5 2.4 2 0 0 2 2 2 1 Insulin-like growth factor binding protein WD40 PF00400.27 KFP05735.1 - 0.00026 20.7 4.7 0.00085 19.1 0.1 2.8 3 1 0 3 3 3 2 WD domain, G-beta repeat GSHPx PF00255.14 KFP05736.1 - 2.2e-35 120.2 0.0 2.9e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KFP05736.1 - 1.1e-07 31.5 0.0 1.9e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFP05736.1 - 0.00031 20.3 0.0 0.00049 19.6 0.0 1.4 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 KFP05736.1 - 0.064 12.8 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 SCO1/SenC HA2 PF04408.18 KFP05737.1 - 7.2e-18 64.4 0.1 7.2e-18 64.4 0.1 3.1 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFP05737.1 - 3e-15 56.0 0.0 4.4e-14 52.2 0.0 3.0 2 1 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFP05737.1 - 9.2e-11 41.4 0.1 2.2e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFP05737.1 - 1.6e-09 37.4 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFP05737.1 - 3.7e-06 27.0 0.1 1.4e-05 25.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFP05737.1 - 0.0033 16.3 0.0 0.0068 15.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KFP05737.1 - 0.019 14.4 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KFP05737.1 - 0.044 13.3 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KFP05737.1 - 0.051 13.5 2.1 1.1 9.2 0.1 3.3 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 KFP05737.1 - 0.096 12.9 4.8 0.63 10.3 0.0 3.0 3 0 0 3 3 2 0 ABC transporter Bestrophin PF01062.16 KFP05737.1 - 0.16 10.9 0.5 0.51 9.2 0.1 2.0 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel rRNA_proc-arch PF13234.1 KFP05738.1 - 2.3e-101 338.4 1.7 3.8e-101 337.7 1.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KFP05738.1 - 8.3e-66 220.6 0.7 1.7e-65 219.6 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KFP05738.1 - 4e-20 71.9 0.0 9.9e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP05738.1 - 1.6e-08 34.2 0.0 4.9e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP05738.1 - 0.0067 16.2 0.0 0.056 13.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PAP2 PF01569.16 KFP05739.1 - 1.5e-21 76.4 2.3 1.6e-21 76.3 0.9 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KFP05739.1 - 0.0079 16.4 3.1 0.0079 16.4 2.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily C-terminal LrgB PF04172.11 KFP05739.1 - 0.035 13.2 0.1 0.072 12.2 0.1 1.5 1 0 0 1 1 1 0 LrgB-like family MVP_shoulder PF11978.3 KFP05739.1 - 0.12 12.3 0.0 4.2 7.2 0.0 2.6 2 1 1 3 3 3 0 Shoulder domain Aa_trans PF01490.13 KFP05740.1 - 6.8e-24 84.0 39.2 2.2e-14 52.8 5.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Pox_A14 PF05767.7 KFP05740.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DEAD PF00270.24 KFP05741.1 - 2.7e-47 160.3 0.0 2.1e-46 157.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP05741.1 - 9e-28 95.9 0.1 2.8e-27 94.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFP05741.1 - 0.0001 21.2 0.0 0.00016 20.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFP05741.1 - 0.0072 16.1 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KFP05741.1 - 0.13 10.6 0.0 0.31 9.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) fn3 PF00041.16 KFP05742.1 - 1.2e-26 92.6 6.9 8.3e-10 38.6 0.2 4.1 4 0 0 4 4 4 4 Fibronectin type III domain Big_3_4 PF13754.1 KFP05742.1 - 0.0025 18.0 0.6 3.4 8.0 0.0 2.9 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 3) Big_5 PF13205.1 KFP05742.1 - 0.0037 17.8 0.5 0.0037 17.8 0.3 2.3 2 1 0 2 2 2 1 Bacterial Ig-like domain Interfer-bind PF09294.5 KFP05742.1 - 0.02 14.9 0.1 5.4 7.0 0.0 2.9 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF4528 PF15031.1 KFP05742.1 - 0.13 11.9 0.5 0.3 10.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) fn3 PF00041.16 KFP05743.1 - 1.2e-33 115.0 10.1 7.2e-10 38.8 0.5 5.6 5 0 0 5 5 5 4 Fibronectin type III domain Lep_receptor_Ig PF06328.6 KFP05743.1 - 5e-33 112.8 0.8 1.5e-32 111.2 0.6 1.9 1 0 0 1 1 1 1 Ig-like C2-type domain EpoR_lig-bind PF09067.5 KFP05743.1 - 4.1e-06 26.7 0.0 9.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 KFP05743.1 - 7.1e-06 26.1 1.1 5.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding DUF3377 PF11857.3 KFP05743.1 - 0.013 15.1 0.4 0.038 13.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Sarcoglycan_2 PF05510.8 KFP05743.1 - 0.073 11.3 0.0 0.13 10.5 0.0 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Ank_2 PF12796.2 KFP05744.1 - 1.3e-45 153.6 4.2 1.7e-12 47.5 0.2 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFP05744.1 - 1.1e-40 135.4 11.5 8.3e-08 31.6 0.0 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 KFP05744.1 - 1.8e-37 126.5 11.6 2.6e-09 37.0 0.5 7.1 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP05744.1 - 3.8e-37 126.0 8.4 1e-09 38.6 0.0 7.3 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP05744.1 - 7.9e-28 93.7 5.0 2.1e-05 24.3 0.0 8.9 9 0 0 9 9 9 6 Ankyrin repeat DUF1908 PF08926.6 KFP05744.1 - 0.00077 18.3 0.0 0.00077 18.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Elicitin PF00964.12 KFP05744.1 - 3.6 7.5 7.2 5.9 6.9 0.1 3.8 3 1 1 4 4 4 0 Elicitin Pkinase PF00069.20 KFP05745.1 - 6.9e-59 199.1 0.0 2.4e-58 197.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05745.1 - 9.8e-33 113.3 0.1 1.6e-31 109.2 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP05745.1 - 4.7e-06 25.7 1.8 0.079 11.9 0.0 3.5 3 1 0 3 3 3 2 Kinase-like zf-RING_2 PF13639.1 KFP05745.1 - 0.00024 20.8 11.6 0.00071 19.3 8.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP05745.1 - 0.017 15.2 5.7 0.057 13.5 4.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 KFP05745.1 - 0.086 12.8 7.7 0.27 11.2 5.3 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain APH PF01636.18 KFP05745.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-Apc11 PF12861.2 KFP05745.1 - 0.15 11.8 4.7 0.43 10.4 3.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 KFP05745.1 - 0.47 10.1 13.3 0.067 12.8 6.2 2.0 2 0 0 2 2 2 0 PHD-finger SET PF00856.23 KFP05746.1 - 2.9e-05 24.4 0.3 0.00012 22.3 0.1 2.2 2 1 0 2 2 2 1 SET domain ELM2 PF01448.19 KFP05747.1 - 2.6e-16 59.9 0.1 1.2e-15 57.8 0.0 2.1 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-binding PF00249.26 KFP05747.1 - 1.8e-05 24.7 0.2 4.3e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain NEMO PF11577.3 KFP05747.1 - 0.00073 19.2 0.3 0.0031 17.2 0.6 1.8 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO GAT PF03127.9 KFP05747.1 - 0.016 15.1 0.0 0.056 13.4 0.0 1.9 1 0 0 1 1 1 0 GAT domain dUTPase PF00692.14 KFP05748.1 - 6.2e-19 67.7 0.1 8.7e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP05748.1 - 0.058 13.3 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.20 KFP05750.1 - 2.5e-69 233.3 0.0 4.5e-69 232.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 KFP05750.1 - 1.3e-39 134.0 2.1 2.8e-19 68.8 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 KFP05750.1 - 6.3e-37 127.0 0.0 1e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP05750.1 - 1.2e-05 24.4 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP05750.1 - 0.063 13.0 1.0 3.2 7.4 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.17 KFP05751.1 - 2.3e-61 205.9 2.3 2.9e-61 205.5 1.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP05751.1 - 6.5e-20 71.8 0.1 1.1e-19 71.1 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP05751.1 - 3.1e-14 52.5 0.3 4.2e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFP05751.1 - 7.9e-08 31.7 1.3 0.00012 21.3 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFP05751.1 - 5.1e-06 25.8 0.6 6.6e-06 25.4 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP05751.1 - 6.3e-05 22.4 0.1 0.00019 20.9 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP05751.1 - 0.0019 18.1 0.1 0.0044 16.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP05751.1 - 0.0024 17.1 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B ORC3_N PF07034.6 KFP05751.1 - 0.0032 16.4 0.5 0.0043 16.0 0.4 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus G-alpha PF00503.15 KFP05751.1 - 0.014 14.1 1.8 2.8 6.5 0.0 3.4 2 2 2 4 4 4 0 G-protein alpha subunit Septin PF00735.13 KFP05751.1 - 0.032 13.2 0.2 0.58 9.1 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 KFP05751.1 - 0.046 13.6 0.2 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFP05751.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain PDEase_I PF00233.14 KFP05754.1 - 6e-106 353.5 5.0 6e-106 353.5 3.5 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DEP PF00610.16 KFP05755.1 - 6.4e-16 57.8 0.0 2.4e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 KFP05755.1 - 1.3e-07 31.3 0.1 4.4e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain DUF148 PF02520.12 KFP05755.1 - 0.014 15.2 0.1 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 AAA_7 PF12775.2 KFP05755.1 - 0.048 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 ELO PF01151.13 KFP05756.1 - 2.3e-61 207.3 27.6 2.6e-61 207.1 19.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 KFP05757.1 - 2.6e-33 112.6 9.1 9.3e-09 34.8 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KFP05757.1 - 0.04 12.0 4.1 6.2 4.8 0.0 3.0 1 1 0 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFP05757.1 - 0.078 11.2 0.1 0.9 7.7 0.1 2.4 1 1 0 1 1 1 0 Cytochrome D1 heme domain TLV_coat PF00429.14 KFP05758.1 - 0.049 12.0 0.2 0.055 11.9 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) NDUFA12 PF05071.11 KFP05759.1 - 6.4e-06 26.5 2.1 6.4e-06 26.5 1.5 1.5 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 EcoEI_R_C PF08463.5 KFP05759.1 - 0.031 14.1 0.2 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 EcoEI R protein C-terminal DUF947 PF06102.7 KFP05759.1 - 0.035 13.9 1.7 0.044 13.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Cytochrom_B562 PF07361.6 KFP05759.1 - 0.058 13.8 0.2 0.071 13.5 0.2 1.3 1 0 0 1 1 1 0 Cytochrome b562 UPF0542 PF15086.1 KFP05760.1 - 6.8e-39 131.4 3.0 7.4e-39 131.3 2.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 7tm_1 PF00001.16 KFP05760.1 - 0.046 12.8 0.0 0.051 12.6 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SieB PF14163.1 KFP05760.1 - 0.055 13.0 0.1 0.063 12.8 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Motilin_ghrelin PF04644.7 KFP05760.1 - 8.9 6.2 8.4 17 5.3 5.8 1.4 1 0 0 1 1 1 0 Motilin/ghrelin SWIM PF04434.12 KFP05761.1 - 0.059 12.8 3.4 0.18 11.3 2.4 1.9 1 0 0 1 1 1 0 SWIM zinc finger Toxin_67 PF15545.1 KFP05762.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative toxin 67 Kinesin PF00225.18 KFP05763.1 - 4e-94 315.0 0.1 4e-94 315.0 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Lipase PF00151.14 KFP05764.1 - 1.3e-107 359.9 0.0 1.6e-107 359.5 0.0 1.1 1 0 0 1 1 1 1 Lipase PLAT PF01477.18 KFP05764.1 - 4.7e-22 78.4 1.4 7.9e-22 77.7 0.9 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain Abhydrolase_6 PF12697.2 KFP05764.1 - 3.6e-08 33.5 0.0 4.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP05764.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family W2 PF02020.13 KFP05764.1 - 0.018 14.9 0.2 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Sec7 PF01369.15 KFP05765.1 - 4.5e-51 173.2 1.0 8.3e-51 172.3 0.7 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KFP05765.1 - 1.8e-39 134.5 1.3 4e-39 133.4 0.5 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KFP05765.1 - 1.1e-12 48.0 0.2 2.6e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP05765.1 - 0.016 15.4 0.3 0.051 13.8 0.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain RNA_pol_Rpb2_2 PF04561.9 KFP05765.1 - 0.07 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 NIPSNAP PF07978.8 KFP05767.1 - 1.6e-53 178.9 0.9 4.4e-27 94.0 0.1 2.0 2 0 0 2 2 2 2 NIPSNAP ABC2_membrane_3 PF12698.2 KFP05768.1 - 1.3e-56 192.0 47.4 5.6e-44 150.5 12.9 3.2 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 KFP05768.1 - 2e-52 177.1 0.0 8.1e-29 100.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFP05768.1 - 1.4e-19 71.1 0.1 3.5e-08 33.7 0.0 4.8 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KFP05768.1 - 0.00077 18.9 2.0 0.061 12.8 0.3 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KFP05768.1 - 0.0037 17.6 5.0 0.02 15.2 0.2 2.7 2 0 0 2 2 2 1 AAA domain DUF4162 PF13732.1 KFP05768.1 - 0.0057 17.1 0.0 0.23 11.9 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.1 KFP05768.1 - 0.012 14.6 0.0 2.6 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain SbcCD_C PF13558.1 KFP05768.1 - 0.02 14.7 0.0 8.5 6.3 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KFP05768.1 - 0.12 11.5 0.3 4.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 THOC7 PF05615.8 KFP05768.1 - 0.41 10.8 0.1 0.94 9.7 0.1 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 Glyco_transf_8 PF01501.15 KFP05769.1 - 1.5e-35 122.7 0.0 2.8e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KFP05769.1 - 0.0024 17.2 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 KFP05769.1 - 0.021 14.5 0.1 0.046 13.4 0.1 1.6 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Bet_v_1 PF00407.14 KFP05769.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family SNF2_N PF00176.18 KFP05770.1 - 1.9e-83 279.7 0.1 2.6e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KFP05770.1 - 1.4e-18 66.7 0.0 3.2e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KFP05770.1 - 5.6e-11 42.1 0.0 2.2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KFP05770.1 - 1.5e-09 37.4 9.7 3.9e-09 36.1 6.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFP05770.1 - 1.8e-08 33.8 7.8 3.9e-08 32.8 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP05770.1 - 4.1e-08 33.1 10.8 4.1e-08 33.1 7.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP05770.1 - 5.8e-08 32.2 10.6 1.4e-07 31.0 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP05770.1 - 2e-06 27.4 8.8 2e-06 27.4 6.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP05770.1 - 1.1e-05 25.2 10.8 2.5e-05 24.0 7.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFP05770.1 - 5.1e-05 23.3 2.5 0.00016 21.7 1.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFP05770.1 - 0.00024 20.8 1.7 0.00056 19.6 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HDA2-3 PF11496.3 KFP05770.1 - 0.0011 17.9 0.3 0.57 8.9 0.0 3.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 zf-RING_UBOX PF13445.1 KFP05770.1 - 0.0038 16.9 7.7 0.0096 15.6 5.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KFP05770.1 - 0.023 14.2 5.3 0.062 12.8 3.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KFP05770.1 - 0.061 13.1 9.2 0.023 14.4 3.9 2.1 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFP05770.1 - 0.21 11.1 5.3 0.45 10.1 3.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tubulin PF00091.20 KFP05772.1 - 4.3e-68 229.3 0.0 5.5e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFP05772.1 - 3.4e-51 172.5 0.0 6.9e-51 171.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFP05772.1 - 0.0022 17.4 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain HPS3_C PF14763.1 KFP05773.1 - 2e-181 602.6 2.9 3.4e-181 601.9 2.0 1.4 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, C-terminal HPS3_Mid PF14762.1 KFP05773.1 - 3.4e-150 499.8 5.4 3.4e-150 499.8 3.8 1.5 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.1 KFP05773.1 - 1.3e-64 217.5 0.0 2.5e-64 216.6 0.0 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 Cu-oxidase_2 PF07731.9 KFP05774.1 - 5.6e-29 100.4 19.6 1.6e-14 53.6 5.0 6.6 6 1 0 6 6 6 5 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFP05774.1 - 5.8e-28 96.9 7.9 1.2e-08 34.6 0.0 5.9 5 1 0 5 5 5 4 Multicopper oxidase L6_membrane PF05805.7 KFP05775.1 - 7.9e-61 205.0 17.1 8.8e-61 204.8 11.8 1.0 1 0 0 1 1 1 1 L6 membrane protein DUF3753 PF12575.3 KFP05775.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3753) DUF2231 PF09990.4 KFP05775.1 - 1.5 9.2 5.9 1.2 9.4 0.2 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) L6_membrane PF05805.7 KFP05776.1 - 4.4e-74 248.2 13.6 5e-74 248.1 9.5 1.0 1 0 0 1 1 1 1 L6 membrane protein Yip1 PF04893.12 KFP05776.1 - 0.00098 18.6 1.6 0.00098 18.6 1.1 1.8 2 0 0 2 2 2 1 Yip1 domain P12 PF12669.2 KFP05776.1 - 6.3 7.0 17.7 0.79 9.9 5.6 3.0 2 0 0 2 2 2 0 Virus attachment protein p12 family L6_membrane PF05805.7 KFP05777.1 - 1.4e-74 249.8 17.3 1.9e-74 249.4 12.0 1.2 1 0 0 1 1 1 1 L6 membrane protein Tic20 PF09685.5 KFP05777.1 - 2.7 7.9 9.5 2.2 8.3 2.6 2.8 2 1 0 2 2 2 0 Tic20-like protein HIM1 PF08732.5 KFP05778.1 - 0.076 11.4 0.0 0.92 7.9 0.0 1.9 2 0 0 2 2 2 0 HIM1 HCaRG PF07258.9 KFP05779.1 - 2.4e-27 95.6 3.0 2.6e-27 95.5 2.1 1.0 1 0 0 1 1 1 1 HCaRG protein SOCS PF12610.3 KFP05779.1 - 0.046 14.0 0.5 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Suppressor of cytokine signalling HTH_1 PF00126.22 KFP05779.1 - 0.057 13.1 0.7 0.4 10.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family zf-RING_2 PF13639.1 KFP05780.1 - 1.6e-15 56.5 7.7 2.8e-15 55.8 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFP05780.1 - 2.8e-12 46.1 0.0 6.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFP05780.1 - 1.3e-08 34.7 3.5 2.7e-08 33.8 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP05780.1 - 1.5e-08 34.1 8.4 2.5e-08 33.4 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP05780.1 - 6.5e-07 29.2 8.6 1.1e-06 28.5 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP05780.1 - 8.9e-07 28.5 7.1 1.4e-06 27.8 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP05780.1 - 1e-06 28.2 5.7 1.7e-06 27.6 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Neur_chan_memb PF02932.11 KFP05780.1 - 0.00039 20.3 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-Apc11 PF12861.2 KFP05780.1 - 0.0025 17.5 6.2 0.0077 16.0 4.3 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_11_kDa PF06143.6 KFP05780.1 - 0.046 13.0 0.6 1.7 8.0 0.1 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family PHD PF00628.24 KFP05780.1 - 0.1 12.2 8.6 0.17 11.5 5.9 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KFP05780.1 - 0.19 11.8 7.7 0.39 10.8 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 KFP05780.1 - 0.53 9.9 8.6 1 8.9 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2976 PF11190.3 KFP05780.1 - 0.79 9.2 3.3 2 8.0 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Cys_rich_CPCC PF14206.1 KFP05780.1 - 1.5 8.4 6.5 9.4 5.8 0.0 3.1 2 1 1 3 3 3 0 Cysteine-rich CPCC FANCL_C PF11793.3 KFP05780.1 - 5.7 6.9 8.9 46 4.0 6.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Profilin PF00235.14 KFP05781.1 - 6.8e-12 45.5 0.0 7.5e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Profilin TSC22 PF01166.13 KFP05782.1 - 1.2e-28 98.8 5.6 1.4e-28 98.6 3.9 1.1 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 KFP05782.1 - 0.0029 17.9 3.0 0.0035 17.6 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIC PF04977.10 KFP05782.1 - 0.0044 16.4 3.2 0.005 16.2 1.9 1.4 1 1 0 1 1 1 1 Septum formation initiator MAD PF05557.8 KFP05782.1 - 0.0048 15.0 2.5 0.0053 14.9 1.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF16 PF01519.11 KFP05782.1 - 0.026 14.7 0.9 0.027 14.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.4 KFP05782.1 - 0.027 14.3 1.5 0.027 14.3 1.0 1.4 2 0 0 2 2 2 0 Haemolysin XhlA CtsR PF05848.6 KFP05782.1 - 0.039 13.9 0.7 0.043 13.7 0.5 1.1 1 0 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) DUF904 PF06005.7 KFP05782.1 - 0.048 13.9 9.0 0.21 11.9 6.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Sipho_Gp157 PF05565.6 KFP05782.1 - 0.048 13.2 0.8 0.056 13.0 0.5 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Cep57_CLD_2 PF14197.1 KFP05782.1 - 0.054 13.4 5.1 0.073 13.0 3.6 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Fzo_mitofusin PF04799.8 KFP05782.1 - 0.13 11.6 1.5 0.15 11.4 1.1 1.0 1 0 0 1 1 1 0 fzo-like conserved region Shugoshin_N PF07558.6 KFP05782.1 - 0.3 10.8 4.7 0.51 10.1 3.2 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.16 KFP05782.1 - 0.85 9.6 5.0 1.1 9.2 3.3 1.5 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 KFP05782.1 - 0.88 9.4 6.1 1.6 8.5 4.2 1.5 1 1 0 1 1 1 0 Basic region leucine zipper eIF2A PF08662.6 KFP05783.1 - 8.1e-81 270.3 2.0 1.4e-78 263.0 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KFP05783.1 - 0.14 12.0 4.6 45 4.1 0.0 4.9 4 1 0 4 4 4 0 WD domain, G-beta repeat Rdx PF10262.4 KFP05784.1 - 1.4e-14 53.8 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Rdx family FAM194 PF14977.1 KFP05785.1 - 7.5e-56 188.3 0.0 8.8e-56 188.1 0.0 1.0 1 0 0 1 1 1 1 FAM194 protein Sina PF03145.11 KFP05786.1 - 2.2e-76 255.9 0.3 2.2e-76 255.9 0.2 1.4 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_3 PF13920.1 KFP05786.1 - 3.3e-05 23.4 6.2 3.3e-05 23.4 4.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP05786.1 - 0.0021 18.0 10.9 0.0021 18.0 7.6 2.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP05786.1 - 0.041 13.6 10.3 0.21 11.3 7.1 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KFP05786.1 - 0.57 9.8 9.9 2 8.1 6.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP05786.1 - 5 7.0 14.5 0.36 10.7 5.9 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4205 PF13898.1 KFP05787.1 - 1.8e-29 102.5 0.0 2e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Claudin_2 PF13903.1 KFP05788.1 - 0.0011 18.7 9.7 0.0011 18.7 6.7 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction UPF0104 PF03706.8 KFP05788.1 - 0.0013 18.0 6.2 0.0013 18.0 4.3 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0104) Synaptobrevin PF00957.16 KFP05788.1 - 0.26 10.8 1.8 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 Synaptobrevin Med12-LCEWAV PF12145.3 KFP05789.1 - 2.6e-191 636.2 0.2 4.2e-191 635.6 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.5 KFP05789.1 - 2.8e-14 52.8 0.2 6.2e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Nipped-B_C PF12830.2 KFP05789.1 - 0.0041 16.7 0.7 1.7 8.2 0.1 3.1 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus 7tm_1 PF00001.16 KFP05790.1 - 2.9e-35 121.6 22.9 3.4e-35 121.4 15.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ni_hydr_CYTB PF01292.15 KFP05790.1 - 0.11 11.9 5.3 0.57 9.5 3.4 2.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PgaD PF13994.1 KFP05790.1 - 0.15 11.5 5.5 0.42 10.0 0.5 2.8 2 1 1 3 3 3 0 PgaD-like protein YtpI PF14007.1 KFP05790.1 - 0.43 10.5 0.1 0.43 10.5 0.0 4.0 3 1 1 4 4 4 0 YtpI-like protein ATP-synt_8 PF00895.15 KFP05790.1 - 3.4 7.9 15.2 4.3 7.6 0.2 4.3 4 0 0 4 4 4 0 ATP synthase protein 8 7tm_1 PF00001.16 KFP05791.1 - 9.5e-44 149.4 21.4 1.1e-43 149.2 14.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP05791.1 - 0.0055 15.8 29.4 0.11 11.5 20.3 2.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF360 PF04020.8 KFP05791.1 - 0.75 10.1 7.4 5.1 7.4 1.0 3.0 2 1 1 3 3 3 0 Membrane protein of unknown function 7tm_1 PF00001.16 KFP05792.1 - 5.9e-36 123.9 19.3 6.9e-36 123.7 13.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP05792.1 - 4.3e-05 22.7 14.8 6.3e-05 22.2 10.2 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2852 PF11014.3 KFP05792.1 - 0.12 12.3 1.1 0.99 9.3 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) NfeD PF01957.13 KFP05792.1 - 0.47 10.5 0.1 0.47 10.5 0.1 2.4 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF373 PF04123.8 KFP05792.1 - 0.92 8.4 4.3 1.1 8.2 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) 7tm_1 PF00001.16 KFP05793.1 - 3.4e-40 137.8 20.6 3.9e-40 137.6 14.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3611 PF12263.3 KFP05793.1 - 0.0019 17.5 0.6 0.0019 17.5 0.4 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3611) DUF2976 PF11190.3 KFP05793.1 - 0.15 11.6 8.7 0.041 13.3 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) NfeD PF01957.13 KFP05793.1 - 3.8 7.6 6.6 1.5 8.9 0.2 2.6 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding zf-LITAF-like PF10601.4 KFP05793.1 - 9.2 6.2 8.5 1.9 8.4 0.2 3.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain I-set PF07679.11 KFP05794.1 - 1.7e-44 149.6 0.0 7.1e-11 41.8 0.0 4.2 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05794.1 - 1e-28 99.2 0.0 9.1e-07 28.9 0.0 4.3 3 1 1 4 4 4 4 Immunoglobulin domain ig PF00047.20 KFP05794.1 - 1.9e-25 88.7 0.0 4.5e-07 29.8 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin domain Ig_3 PF13927.1 KFP05794.1 - 8.1e-25 87.1 0.0 1.5e-06 28.5 0.0 4.5 4 1 0 4 4 4 4 Immunoglobulin domain V-set PF07686.12 KFP05794.1 - 5.7e-15 55.2 0.0 0.0016 18.3 0.0 4.4 3 1 1 4 4 4 4 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP05794.1 - 7e-07 29.0 3.7 0.079 12.8 0.0 4.4 4 1 1 5 5 5 3 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 KFP05794.1 - 0.072 13.0 0.0 7.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 LRR_8 PF13855.1 KFP05795.1 - 5e-28 96.6 9.7 4.2e-13 48.8 0.4 3.3 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP05795.1 - 3.5e-15 55.2 11.0 0.00045 19.7 0.4 4.2 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP05795.1 - 1.2e-12 46.0 9.5 0.16 12.1 0.0 7.1 6 1 1 7 7 7 4 Leucine Rich Repeat LRR_5 PF13306.1 KFP05795.1 - 1.8e-08 34.1 0.3 0.00099 18.8 0.0 2.4 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFP05795.1 - 0.02 14.9 10.3 6.5 7.1 0.0 6.2 6 1 1 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 KFP05795.1 - 0.097 12.9 12.6 31 5.3 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat 7tm_1 PF00001.16 KFP05796.1 - 1.5e-40 138.9 15.2 1.8e-40 138.6 10.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4064 PF13273.1 KFP05796.1 - 0.041 13.9 3.0 5.7 7.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) zf-CCCH PF00642.19 KFP05797.1 - 6.1e-10 38.5 25.4 0.00025 20.6 0.7 5.1 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1540 PF07561.6 KFP05797.1 - 0.88 9.6 5.2 23 5.1 0.1 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1540) 7tm_1 PF00001.16 KFP05798.1 - 1.4e-47 162.0 20.0 2.2e-47 161.3 13.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TrbE PF11100.3 KFP05798.1 - 3.1 7.7 11.8 0.17 11.7 3.1 2.6 2 1 0 2 2 2 0 Conjugal transfer protein TrbE RhoGEF PF00621.15 KFP05799.1 - 2.4e-38 131.7 5.7 4.5e-38 130.9 4.0 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 KFP05799.1 - 4.5e-12 45.1 0.1 1.3e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP05799.1 - 3.5e-11 42.5 0.1 6.9e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP05799.1 - 4.5e-10 38.8 0.0 1.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFP05799.1 - 5e-08 33.0 3.0 6.2e-08 32.7 0.1 2.4 2 1 0 2 2 2 1 PH domain NAGLU_C PF12972.2 KFP05799.1 - 0.034 13.5 0.2 0.073 12.4 0.1 1.5 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain HA2 PF04408.18 KFP05800.1 - 1.4e-22 79.6 0.1 2.9e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFP05800.1 - 2.1e-18 66.1 0.0 8.5e-18 64.2 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFP05800.1 - 2.4e-13 49.7 0.1 5.2e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFP05800.1 - 1.9e-12 46.9 0.2 1.4e-11 44.1 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFP05800.1 - 2.6e-08 34.0 0.2 7.1e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFP05800.1 - 0.00048 19.8 0.1 0.0015 18.2 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 KFP05800.1 - 0.0014 17.8 0.0 0.0038 16.3 0.0 1.7 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 KFP05800.1 - 0.0091 15.9 0.7 0.15 11.9 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KFP05800.1 - 0.027 14.7 0.1 0.027 14.7 0.1 2.7 2 1 1 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 KFP05800.1 - 0.039 13.9 0.1 3.4 7.6 0.0 3.0 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.1 KFP05800.1 - 0.059 13.3 0.3 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KFP05800.1 - 0.059 12.2 0.0 0.14 11.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 KFP05800.1 - 0.23 11.7 0.8 0.8 10.0 0.1 2.3 2 1 0 2 2 2 0 ABC transporter Peptidase_M13_N PF05649.8 KFP05802.1 - 3.7e-131 437.7 1.3 3.7e-131 437.7 0.9 1.5 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFP05802.1 - 7.9e-64 214.6 0.0 1.6e-63 213.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 Acatn PF13000.2 KFP05804.1 - 7.9e-99 331.6 16.8 6.7e-58 196.5 4.5 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 GATase PF00117.23 KFP05805.1 - 1.6e-39 135.3 0.0 1.1e-38 132.5 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KFP05805.1 - 1.4e-30 104.8 0.0 3.1e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KFP05805.1 - 2.1e-13 49.7 0.1 1.6e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KFP05805.1 - 7.8e-13 48.3 0.0 2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 KFP05805.1 - 3.4e-08 33.0 0.1 2.6e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KFP05805.1 - 2.4e-06 27.2 0.0 4.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KFP05805.1 - 2.4e-06 26.3 0.0 9.7e-06 24.3 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.15 KFP05805.1 - 0.00033 20.2 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.9 KFP05805.1 - 0.00043 19.7 0.1 0.00099 18.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 KFP05805.1 - 0.00093 19.0 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 KFP05805.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase rve PF00665.21 KFP05805.1 - 0.017 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain CW_binding_2 PF04122.7 KFP05805.1 - 0.019 15.1 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 LytR_C PF13399.1 KFP05805.1 - 0.023 15.0 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator GATase_3 PF07685.9 KFP05805.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Aldo_ket_red PF00248.16 KFP05806.1 - 3.2e-30 104.9 0.0 4.3e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KFP05807.1 - 3.8e-17 62.0 0.0 4.3e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRAP-gamma PF07074.7 KFP05808.1 - 9.7e-90 298.5 8.0 1.1e-89 298.4 5.5 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Kei1 PF08552.6 KFP05808.1 - 0.014 15.0 2.5 0.018 14.6 1.8 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3784 PF12650.2 KFP05808.1 - 0.25 11.3 5.7 2.7 7.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF2681 PF10883.3 KFP05808.1 - 6.5 7.0 6.5 3.1e+02 1.6 4.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) PARP PF00644.15 KFP05809.1 - 2.9e-35 121.5 4.2 3.8e-34 117.9 2.9 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain GAS PF13851.1 KFP05810.1 - 0.0046 16.1 31.2 0.23 10.6 8.6 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 KFP05810.1 - 0.011 14.4 25.3 0.019 13.6 7.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.4 KFP05810.1 - 0.011 14.4 22.2 0.15 10.7 5.1 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 IncA PF04156.9 KFP05810.1 - 0.029 13.9 36.9 0.23 11.0 11.2 2.7 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 KFP05810.1 - 0.062 13.1 34.4 0.064 13.1 9.0 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 KFP05810.1 - 0.61 9.8 27.9 0.29 10.9 4.2 3.8 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KFP05810.1 - 0.74 8.9 6.5 3 6.9 0.1 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KFP05810.1 - 0.9 9.8 10.6 16 5.8 0.0 4.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KFP05810.1 - 1.2 8.9 14.0 1.6 8.5 1.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KFP05810.1 - 1.9 8.8 27.2 4.8 7.5 0.8 4.4 1 1 2 4 4 4 0 Protein of unknown function (DUF972) Syntaxin-6_N PF09177.6 KFP05810.1 - 2 8.8 16.3 5.5 7.4 2.4 3.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal APG6 PF04111.7 KFP05810.1 - 2.1 7.3 31.1 0.58 9.1 8.9 2.1 1 1 0 2 2 2 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 KFP05810.1 - 2.9 7.7 31.7 4.8 7.0 8.2 2.6 2 1 0 2 2 2 0 Tropomyosin like Fib_alpha PF08702.5 KFP05810.1 - 3.2 7.8 20.0 4.4 7.4 3.7 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CCDC155 PF14662.1 KFP05810.1 - 3.2 7.2 32.1 0.2 11.2 2.5 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 Ku_C PF03730.9 KFP05810.1 - 3.9 8.0 15.6 0.25 11.9 2.3 3.5 2 2 2 4 4 4 0 Ku70/Ku80 C-terminal arm DUF4559 PF15112.1 KFP05810.1 - 4.9 6.2 20.6 3.3 6.7 5.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Bacillus_HBL PF05791.6 KFP05810.1 - 6.2 6.1 18.7 0.086 12.1 2.5 3.2 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) UPF0449 PF15136.1 KFP05810.1 - 8 6.7 18.4 2.4 8.4 3.0 3.8 2 2 2 4 4 4 0 Uncharacterised protein family UPF0449 FliD_N PF02465.13 KFP05810.1 - 8.9 6.7 15.1 6.9 7.1 3.6 3.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus GAS PF13851.1 KFP05811.1 - 0.26 10.4 59.8 1.1 8.4 16.4 3.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Cyclin_N PF00134.18 KFP05812.1 - 9.2e-11 41.3 0.2 4.4e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP05812.1 - 2.4e-05 24.2 0.1 8.6e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.14 KFP05812.1 - 0.00016 21.4 0.3 0.13 12.1 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat DUF936 PF06075.7 KFP05812.1 - 0.0009 18.2 14.6 0.00093 18.2 10.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) PH PF00169.24 KFP05813.1 - 2.5e-11 43.6 2.8 5.3e-11 42.6 0.3 2.5 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 KFP05813.1 - 3.5e-08 33.6 2.7 4.4e-07 30.1 1.8 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 KFP05813.1 - 0.077 13.1 0.4 0.38 10.9 0.3 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Homeobox PF00046.24 KFP05814.1 - 2.6e-06 26.9 8.8 0.0037 16.8 2.3 2.4 2 0 0 2 2 2 2 Homeobox domain Mlf1IP PF10248.4 KFP05816.1 - 9.6e-78 259.7 8.3 1.1e-77 259.6 5.7 1.0 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein GTP_EFTU PF00009.22 KFP05817.1 - 1.1e-61 207.5 0.0 1.7e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFP05817.1 - 3.6e-32 110.4 0.2 1.2e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 KFP05817.1 - 4.1e-31 106.6 0.0 1e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KFP05817.1 - 1.9e-24 85.3 0.0 4.7e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFP05817.1 - 3.2e-15 55.9 0.0 9.7e-15 54.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFP05817.1 - 0.004 17.0 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KFP05817.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.5 KFP05817.1 - 0.12 11.6 0.0 0.38 9.9 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Latexin PF06907.7 KFP05818.1 - 2.2e-43 148.0 0.1 2.6e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Latexin Latexin PF06907.7 KFP05819.1 - 1.8e-71 239.7 0.2 2.1e-71 239.6 0.1 1.0 1 0 0 1 1 1 1 Latexin IQ-like PF15157.1 KFP05820.1 - 4.1e-44 148.7 2.0 4.5e-44 148.5 1.4 1.0 1 0 0 1 1 1 1 IQ-like LCD1 PF09798.4 KFP05820.1 - 0.023 12.7 1.2 0.025 12.5 0.8 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Fmp27_WPPW PF10359.4 KFP05820.1 - 0.029 12.8 0.7 0.031 12.7 0.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IQ PF00612.22 KFP05820.1 - 0.072 12.7 0.2 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Allexi_40kDa PF05549.6 KFP05820.1 - 0.15 11.2 0.5 0.16 11.1 0.3 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein TBPIP PF07106.8 KFP05820.1 - 0.19 11.2 2.9 0.23 10.9 2.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KFP05820.1 - 0.67 9.5 2.9 0.79 9.2 2.0 1.1 1 0 0 1 1 1 0 IncA protein SCHIP-1 PF10148.4 KFP05821.1 - 1.2e-121 404.5 14.5 1.3e-121 404.3 10.0 1.0 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 FEZ PF07763.8 KFP05821.1 - 5.7e-05 22.9 6.2 0.0001 22.1 4.3 1.6 1 1 0 1 1 1 1 FEZ-like protein FAM117 PF15388.1 KFP05821.1 - 0.8 8.8 7.0 1.8 7.7 4.8 1.5 1 1 0 1 1 1 0 Protein Family FAM117 FIIND PF13553.1 KFP05822.1 - 1.4e-21 77.0 0.0 1.6e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Function to find zf-RING_2 PF13639.1 KFP05823.1 - 1.7e-09 37.3 6.4 1.7e-09 37.3 4.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.19 KFP05823.1 - 2.1e-08 33.8 2.3 2.1e-08 33.8 1.6 3.3 4 0 0 4 4 4 1 B-box zinc finger zf-C3HC4 PF00097.20 KFP05823.1 - 1.4e-07 31.0 3.8 1.4e-07 31.0 2.7 2.8 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP05823.1 - 2.5e-07 30.2 4.2 2.5e-07 30.2 2.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFP05823.1 - 2.9e-07 30.4 7.1 2.9e-07 30.4 4.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP05823.1 - 2.2e-06 27.2 3.8 2.2e-06 27.2 2.6 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFP05823.1 - 4.3e-06 26.3 2.9 4.3e-06 26.3 2.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFP05823.1 - 1.9e-05 24.4 7.2 1.9e-05 24.4 5.0 3.1 2 2 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFP05823.1 - 0.0022 17.7 5.6 0.0022 17.7 3.9 2.1 2 1 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.10 KFP05823.1 - 0.0043 16.9 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 U-box domain DUF349 PF03993.7 KFP05823.1 - 0.0076 16.3 1.7 0.0081 16.2 0.1 1.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF349) Mu-like_Com PF10122.4 KFP05823.1 - 0.02 13.9 1.5 0.12 11.4 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com Prok-RING_4 PF14447.1 KFP05823.1 - 0.032 13.7 2.1 0.032 13.7 1.4 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFP05823.1 - 0.47 10.0 4.6 2.9 7.5 3.2 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DASH_Dad3 PF08656.5 KFP05823.1 - 0.72 9.5 5.7 0.84 9.3 2.6 2.2 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF848 PF05852.6 KFP05823.1 - 4.6 7.0 9.7 5.7 6.7 5.6 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Arm PF00514.18 KFP05824.1 - 2e-89 290.7 21.0 9.4e-14 50.6 0.2 9.8 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP05824.1 - 1.1e-24 86.5 0.0 4.5e-08 33.2 0.0 5.7 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 KFP05824.1 - 1e-18 65.6 4.5 0.0014 18.5 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat IBB PF01749.15 KFP05824.1 - 2.7e-18 65.8 2.6 5.1e-18 65.0 1.8 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFP05824.1 - 2.4e-16 59.6 5.3 2e-06 28.0 0.0 6.0 4 3 3 7 7 7 4 HEAT-like repeat Adaptin_N PF01602.15 KFP05824.1 - 1.4e-07 30.2 2.1 1.1e-06 27.3 1.5 2.3 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.8 KFP05824.1 - 1.2e-06 27.7 1.2 0.046 12.8 0.2 3.5 2 1 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.3 KFP05824.1 - 4.4e-06 26.6 0.5 1.1 9.2 0.1 4.3 4 1 1 5 5 5 3 V-ATPase subunit H V-ATPase_H_N PF03224.9 KFP05824.1 - 3.4e-05 23.1 1.2 0.0012 18.0 0.3 2.6 1 1 0 2 2 2 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFP05824.1 - 0.00086 17.6 0.7 0.19 9.9 0.1 3.2 2 2 1 3 3 3 1 Proteasome non-ATPase 26S subunit Atx10homo_assoc PF09759.4 KFP05824.1 - 0.0011 18.6 0.2 5.5 6.7 0.1 4.3 2 1 2 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Mo25 PF08569.6 KFP05824.1 - 0.021 13.8 0.1 0.078 11.9 0.0 2.0 2 1 0 2 2 2 0 Mo25-like Cnd3 PF12719.2 KFP05824.1 - 0.056 12.4 0.1 4.7 6.0 0.0 3.6 2 2 2 4 4 4 0 Nuclear condensing complex subunits, C-term domain RasGEF_N_2 PF14663.1 KFP05824.1 - 0.065 13.1 0.2 1 9.3 0.0 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1981 PF09324.5 KFP05824.1 - 0.092 12.2 0.3 1.6 8.2 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) CTNNBL PF08216.6 KFP05824.1 - 1.5 8.4 11.2 11 5.6 0.2 5.1 5 2 2 7 7 7 0 Catenin-beta-like, Arm-motif containing nuclear Arf PF00025.16 KFP05825.1 - 4.7e-59 198.5 0.0 5.2e-59 198.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP05825.1 - 2.3e-15 56.3 0.0 2.6e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFP05825.1 - 3e-15 55.8 3.6 3.7e-12 45.6 0.6 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KFP05825.1 - 2.1e-12 47.5 0.1 2.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFP05825.1 - 3e-09 36.3 0.0 3.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFP05825.1 - 6.9e-09 35.1 0.1 8.1e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP05825.1 - 2.1e-06 27.6 0.0 4.4e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP05825.1 - 3e-06 26.7 0.0 1.5e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Thioredoxin_2 PF13098.1 KFP05825.1 - 0.025 14.7 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain PP2C PF00481.16 KFP05826.1 - 4.6e-52 176.9 0.0 5.2e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFP05826.1 - 3.9e-10 39.5 0.0 6.1e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFP05826.1 - 9.8e-05 22.1 0.0 0.019 14.6 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) NOPS PF08075.6 KFP05826.1 - 0.075 13.4 0.2 2.9 8.3 0.0 2.4 2 0 0 2 2 2 0 NOPS (NUC059) domain Trypsin PF00089.21 KFP05827.1 - 2.5e-69 233.2 0.0 2.8e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.6 KFP05827.1 - 6.3e-10 38.7 0.1 8e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFP05827.1 - 0.00056 19.8 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Lectin_C PF00059.16 KFP05828.1 - 1.8e-13 51.0 0.8 3.1e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 Lectin C-type domain DUF3377 PF11857.3 KFP05828.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EURL PF06937.6 KFP05829.1 - 6.9e-152 504.7 5.9 7.7e-152 504.5 4.1 1.0 1 0 0 1 1 1 1 EURL protein FEZ PF07763.8 KFP05829.1 - 0.0022 17.7 0.8 0.0035 17.0 0.5 1.3 1 0 0 1 1 1 1 FEZ-like protein APG6 PF04111.7 KFP05829.1 - 0.042 12.8 1.3 0.07 12.1 0.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-CCHC_2 PF13696.1 KFP05829.1 - 0.047 13.1 4.9 0.25 10.8 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Med21 PF11221.3 KFP05829.1 - 0.17 11.8 2.3 5.4 6.9 0.9 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex V-set PF07686.12 KFP05830.1 - 1e-18 67.2 0.3 6.6e-15 54.9 0.0 2.8 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFP05830.1 - 2.4e-17 62.5 0.0 3.2e-08 33.3 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05830.1 - 1.1e-14 54.2 1.0 3.5e-09 36.6 0.1 2.9 2 1 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP05830.1 - 1.6e-12 47.7 0.3 8.5e-07 29.3 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP05830.1 - 3.4e-10 39.9 0.2 9.4e-05 22.4 0.0 3.3 2 1 0 2 2 2 2 Immunoglobulin domain Herpes_gE PF02480.11 KFP05830.1 - 2e-05 23.0 1.0 0.034 12.4 0.1 3.0 1 1 2 3 3 3 2 Alphaherpesvirus glycoprotein E FAM163 PF15069.1 KFP05830.1 - 4.8e-05 23.9 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 FAM163 family Shisa PF13908.1 KFP05830.1 - 0.00068 19.8 0.4 0.0013 18.9 0.3 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 KFP05830.1 - 0.00077 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KFP05830.1 - 0.001 18.5 0.5 0.0022 17.5 0.3 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 V-set_CD47 PF08204.6 KFP05830.1 - 0.0044 16.7 0.0 1.2 8.9 0.0 2.5 2 1 0 2 2 2 1 CD47 immunoglobulin-like domain Syndecan PF01034.15 KFP05830.1 - 0.01 15.4 0.4 0.032 13.8 0.1 1.9 2 0 0 2 2 2 0 Syndecan domain Sp38 PF07354.7 KFP05830.1 - 0.011 14.3 0.0 0.023 13.3 0.0 1.4 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) LRR19-TM PF15176.1 KFP05830.1 - 0.027 14.1 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain C2-set PF05790.10 KFP05830.1 - 0.056 13.4 0.3 5.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Immunoglobulin C2-set domain RSN1_TM PF13967.1 KFP05830.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Keratin PF02422.11 KFP05831.1 - 2.3e-16 59.5 11.3 2.5e-16 59.4 7.9 1.0 1 0 0 1 1 1 1 Keratin LELP1 PF15042.1 KFP05831.1 - 1.6 8.9 6.0 1.9 8.6 4.2 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Keratin PF02422.11 KFP05832.1 - 6.5e-12 45.2 11.8 7.8e-12 45.0 8.2 1.2 1 0 0 1 1 1 1 Keratin PAAR_motif PF05488.8 KFP05832.1 - 0.77 9.7 3.9 0.86 9.6 1.8 1.6 1 1 1 2 2 2 0 PAAR motif LRRNT PF01462.13 KFP05832.1 - 1.7 8.2 11.5 0.21 11.1 5.1 1.7 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DUF3432 PF11914.3 KFP05832.1 - 4.6 7.3 10.8 3.1 7.9 6.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP05833.1 - 2.6e-20 72.2 12.7 3e-20 72.0 8.8 1.1 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFP05833.1 - 0.031 14.2 3.6 0.039 13.9 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP05834.1 - 1e-18 67.1 17.8 1e-18 67.1 12.3 2.0 1 1 1 2 2 2 1 Keratin TIL PF01826.12 KFP05834.1 - 0.26 11.4 10.1 0.42 10.7 7.0 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF3432 PF11914.3 KFP05834.1 - 0.56 10.2 4.1 0.81 9.7 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP05835.1 - 6.8e-23 80.4 9.5 7.3e-23 80.3 6.6 1.0 1 0 0 1 1 1 1 Keratin Cornifin PF02389.10 KFP05835.1 - 0.015 15.0 5.8 0.015 15.0 4.0 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3432 PF11914.3 KFP05835.1 - 0.12 12.4 2.6 0.15 12.1 1.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP05836.1 - 4.3e-19 68.2 15.8 4.6e-19 68.1 10.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP05837.1 - 4.1e-18 65.1 16.7 4.3e-18 65.0 11.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP05838.1 - 1.5e-20 73.0 11.0 1.6e-20 72.9 7.6 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFP05838.1 - 0.91 9.5 8.8 2.1 8.4 6.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP05839.1 - 8.8e-23 80.1 9.4 9.1e-23 80.0 6.5 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP05840.1 - 4.2e-22 77.9 8.9 4.4e-22 77.8 6.2 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP05841.1 - 1.8e-34 117.6 13.8 3.2e-34 116.7 9.5 1.5 1 1 0 1 1 1 1 Keratin HEV_ORF1 PF02444.11 KFP05842.1 - 0.058 13.6 6.9 0.059 13.5 4.8 1.0 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) Keratin PF02422.11 KFP05843.1 - 2.8e-38 129.8 12.2 2.8e-38 129.8 8.5 2.0 1 1 1 2 2 2 2 Keratin Lamprin PF06403.6 KFP05843.1 - 0.61 9.8 25.1 0.81 9.4 17.4 1.2 1 0 0 1 1 1 0 Lamprin HEV_ORF1 PF02444.11 KFP05844.1 - 0.18 12.0 5.8 0.18 11.9 4.1 1.1 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) Keratin PF02422.11 KFP05845.1 - 1e-35 121.6 12.7 1e-35 121.6 8.8 2.4 1 1 1 2 2 2 1 Keratin Tetraspannin PF00335.15 KFP05847.1 - 3.4e-46 157.3 11.0 7.5e-46 156.1 7.7 1.5 1 1 0 1 1 1 1 Tetraspanin family GATase_5 PF13507.1 KFP05847.1 - 0.025 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Claudin_2 PF13903.1 KFP05847.1 - 0.36 10.4 4.0 0.34 10.5 1.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 KFP05848.1 - 1.4e-51 174.8 11.5 2.3e-51 174.1 8.0 1.3 1 1 0 1 1 1 1 Tetraspanin family p53-inducible11 PF14936.1 KFP05849.1 - 2e-97 324.3 1.0 2.3e-97 324.1 0.7 1.0 1 0 0 1 1 1 1 Tumour protein p53-inducible protein 11 DUF3483 PF11982.3 KFP05849.1 - 0.007 15.6 0.2 0.01 15.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3483) SET PF00856.23 KFP05850.1 - 0.0013 19.0 2.0 0.0083 16.4 0.0 2.9 2 2 0 2 2 2 1 SET domain C2 PF00168.25 KFP05851.1 - 4.4e-21 74.5 0.0 6.4e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.19 KFP05851.1 - 6.7e-05 22.6 0.2 0.011 15.4 0.0 2.9 2 1 1 3 3 3 2 Phosphoinositide 3-kinase C2 Astacin PF01400.19 KFP05852.1 - 2.2e-61 206.5 0.3 3.9e-61 205.7 0.0 1.5 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) CUB PF00431.15 KFP05852.1 - 1.6e-30 105.3 0.1 4.5e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 CUB domain Dynamin_N PF00350.18 KFP05853.1 - 6.3e-20 71.6 0.0 4e-19 69.0 0.0 2.3 2 1 0 2 2 2 1 Dynamin family EF-hand_4 PF12763.2 KFP05853.1 - 1.3e-15 56.9 0.0 5.7e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 KFP05853.1 - 8.5e-08 32.1 0.0 5e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFP05853.1 - 0.00018 21.9 0.1 0.011 16.2 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein EF-hand_1 PF00036.27 KFP05853.1 - 0.001 18.1 0.6 0.0036 16.4 0.1 2.2 2 0 0 2 2 2 1 EF hand GTP_EFTU PF00009.22 KFP05853.1 - 0.0049 16.3 0.0 0.036 13.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain UPF0278 PF08745.6 KFP05853.1 - 0.03 13.5 0.2 0.068 12.4 0.0 1.6 2 0 0 2 2 2 0 UPF0278 family AAA_28 PF13521.1 KFP05853.1 - 0.032 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFP05853.1 - 0.037 14.1 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KFP05853.1 - 0.041 13.3 0.1 8.2 5.8 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain EF-hand_7 PF13499.1 KFP05853.1 - 0.05 13.7 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair MobB PF03205.9 KFP05853.1 - 0.075 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KFP05853.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 KFP05853.1 - 0.12 11.8 0.0 0.6 9.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family PLA2_B PF01735.13 KFP05854.1 - 1.2e-26 92.9 0.0 1.6e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 KFP05855.1 - 2.7e-36 124.8 0.1 1.1e-32 112.8 0.0 2.4 2 1 0 2 2 2 2 Lysophospholipase catalytic domain C2 PF00168.25 KFP05855.1 - 6.6e-18 64.3 0.3 6.6e-18 64.3 0.2 1.9 2 0 0 2 2 2 1 C2 domain PLA2_B PF01735.13 KFP05856.1 - 2e-33 115.3 0.1 4.1e-32 110.9 0.0 2.5 2 1 1 3 3 3 1 Lysophospholipase catalytic domain C2 PF00168.25 KFP05856.1 - 3.4e-15 55.6 0.6 1.4e-14 53.6 0.3 2.2 2 0 0 2 2 2 1 C2 domain ECH PF00378.15 KFP05856.1 - 0.18 10.8 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family PLA2_B PF01735.13 KFP05857.1 - 1.5e-25 89.3 0.0 1.8e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF1133 PF06576.6 KFP05857.1 - 0.0082 15.3 0.1 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1133) C2 PF00168.25 KFP05858.1 - 2.6e-16 59.2 2.8 1.6e-15 56.6 0.4 2.0 1 1 1 2 2 2 2 C2 domain PLA2_B PF01735.13 KFP05859.1 - 2.6e-40 138.0 0.2 8.1e-34 116.6 0.0 3.0 2 1 1 3 3 3 3 Lysophospholipase catalytic domain CNH PF00780.17 KFP05860.1 - 3.2e-50 171.1 0.1 7e-50 169.9 0.1 1.6 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 KFP05860.1 - 2.1e-32 111.3 2.8 2.1e-32 111.3 2.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KFP05860.1 - 1.4e-31 108.8 4.8 1.4e-31 108.8 3.4 2.7 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 KFP05860.1 - 2.2e-11 43.5 10.4 1.2e-06 28.2 0.7 4.0 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-FCS PF06467.9 KFP05860.1 - 0.0078 15.8 0.2 0.02 14.5 0.1 1.8 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif Lgl_C PF08596.5 KFP05860.1 - 0.072 11.5 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Apc3 PF12895.2 KFP05860.1 - 0.27 11.4 3.3 0.92 9.6 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Lung_7-TM_R PF06814.8 KFP05861.1 - 3.9e-80 268.9 24.8 2.4e-78 263.0 17.2 2.1 1 1 0 1 1 1 1 Lung seven transmembrane receptor Glyco_hydro_31 PF01055.21 KFP05862.1 - 1.2e-149 498.8 4.6 3.7e-149 497.3 3.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFP05862.1 - 5.4e-17 61.3 0.0 1.5e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Peptidase_C2 PF00648.16 KFP05863.1 - 1.3e-148 493.8 0.8 2.8e-147 489.4 0.5 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KFP05863.1 - 3.5e-59 198.6 0.0 8.8e-59 197.3 0.0 1.7 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 KFP05863.1 - 6.6e-19 65.7 12.4 5.1e-07 28.5 0.1 6.1 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KFP05863.1 - 1.1e-17 62.2 6.5 0.0011 18.6 0.0 5.8 6 0 0 6 6 6 4 EF-hand domain EF-hand_7 PF13499.1 KFP05863.1 - 2.6e-14 53.0 10.4 1.5e-05 24.9 0.2 4.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP05863.1 - 4.2e-14 51.9 11.4 1.5e-09 37.2 0.5 4.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP05863.1 - 2e-12 45.8 8.8 0.00026 20.1 0.0 4.7 5 0 0 5 5 5 3 EF hand CEP76-C2 PF15627.1 KFP05863.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain EF-hand_4 PF12763.2 KFP05863.1 - 0.024 14.3 3.5 0.55 10.0 0.2 2.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.27 KFP05864.1 - 4.2e-32 108.8 5.2 5.9e-05 22.7 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFP05864.1 - 0.0084 15.8 0.1 0.086 12.6 0.0 2.6 1 1 2 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 KFP05864.1 - 0.089 13.0 1.4 1.9e+02 2.5 0.0 4.8 6 0 0 6 6 6 0 PQQ-like domain PQQ PF01011.16 KFP05864.1 - 0.37 10.4 0.9 2.1e+02 1.7 0.0 4.4 5 0 0 5 5 5 0 PQQ enzyme repeat SNARE PF05739.14 KFP05865.1 - 2.4e-17 62.3 13.1 1.1e-11 44.2 2.6 2.5 2 0 0 2 2 2 2 SNARE domain SNAP-25 PF00835.14 KFP05865.1 - 1e-12 48.5 1.1 1.8e-12 47.8 0.7 1.4 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.3 KFP05865.1 - 9.8e-06 25.5 5.6 0.0037 17.2 0.9 2.7 2 1 1 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.7 KFP05865.1 - 0.065 13.4 3.4 4.7 7.5 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec20 PF03908.8 KFP05865.1 - 0.094 12.4 2.1 0.087 12.5 0.5 1.6 2 0 0 2 2 2 0 Sec20 DUF16 PF01519.11 KFP05865.1 - 0.1 12.8 1.7 0.51 10.5 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.7 KFP05865.1 - 0.62 9.8 6.3 0.2 11.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LRR_4 PF12799.2 KFP05866.1 - 1.8e-28 97.6 30.8 1.2e-08 34.3 2.8 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP05866.1 - 2.9e-21 74.9 22.1 5.1e-14 51.7 1.3 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFP05866.1 - 4.1e-18 62.6 20.9 0.035 14.1 0.2 8.0 8 0 0 8 8 8 7 Leucine Rich Repeat LRR_7 PF13504.1 KFP05866.1 - 3.4e-11 41.4 22.6 0.14 12.4 0.0 7.9 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 KFP05866.1 - 6.7e-09 34.9 24.7 0.44 10.7 0.6 7.6 6 1 1 7 7 7 5 Leucine Rich repeat LRR_9 PF14580.1 KFP05866.1 - 7.5e-05 22.3 5.8 0.0095 15.5 0.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat HAUS2 PF15003.1 KFP05867.1 - 2.5e-39 135.0 6.7 2.8e-39 134.8 4.7 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Laminin_II PF06009.7 KFP05867.1 - 0.015 15.0 0.6 0.027 14.2 0.1 1.6 2 0 0 2 2 2 0 Laminin Domain II DUF3910 PF13049.1 KFP05867.1 - 0.032 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) KNOX2 PF03791.8 KFP05867.1 - 0.08 12.2 0.3 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 KNOX2 domain Vac_Fusion PF02346.11 KFP05867.1 - 1.2 8.6 5.6 1.9 7.9 0.1 2.8 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Kinesin PF00225.18 KFP05868.1 - 5.2e-74 248.9 3.7 3.6e-40 137.6 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain FHA PF00498.21 KFP05868.1 - 2.9e-06 27.2 0.2 9.8e-06 25.6 0.2 2.0 1 0 0 1 1 1 1 FHA domain START PF01852.14 KFP05869.1 - 1.9e-09 37.1 0.0 3.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 START domain DUF883 PF05957.8 KFP05869.1 - 4.6 7.7 9.2 0.35 11.2 2.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.20 KFP05870.1 - 1.8e-31 109.2 0.0 3e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP05870.1 - 6.7e-18 64.6 0.0 1.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP05870.1 - 0.12 12.1 0.0 6.6 6.3 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tetraspannin PF00335.15 KFP05871.1 - 1e-37 129.5 9.7 1.2e-37 129.3 6.7 1.0 1 0 0 1 1 1 1 Tetraspanin family Peptidase_U4 PF03419.8 KFP05871.1 - 0.036 13.1 0.8 0.045 12.8 0.1 1.4 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Cation_efflux PF01545.16 KFP05871.1 - 0.062 12.3 0.4 0.088 11.8 0.3 1.2 1 0 0 1 1 1 0 Cation efflux family DUF2627 PF11118.3 KFP05871.1 - 0.13 12.3 1.5 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) ArfGap PF01412.13 KFP05871.1 - 0.55 10.0 6.0 0.49 10.1 3.1 1.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf RVT_1 PF00078.22 KFP05872.1 - 8.2e-19 67.8 0.0 1.9e-18 66.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) dUTPase PF00692.14 KFP05873.1 - 3.2e-18 65.4 0.0 4.4e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 dUTPase TIR PF01582.15 KFP05874.1 - 2.2e-26 91.9 0.0 3.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 TIR domain Ig_3 PF13927.1 KFP05874.1 - 3.7e-07 30.5 0.0 8.6e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP05874.1 - 8.2e-06 25.5 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFP05874.1 - 5.6e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain TIR_2 PF13676.1 KFP05874.1 - 0.0001 22.4 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain Ig_2 PF13895.1 KFP05874.1 - 0.00045 20.2 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Hormone_recep PF00104.25 KFP05875.1 - 9.3e-20 70.6 0.0 8.8e-19 67.4 0.0 1.9 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor NR_Repeat PF14046.1 KFP05875.1 - 0.15 11.8 1.7 0.49 10.1 1.2 1.9 1 1 0 1 1 1 0 Nuclear receptor repeat DUF4569 PF15133.1 KFP05876.1 - 1e-104 350.2 7.2 1.2e-104 350.0 5.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) FGGY_N PF00370.16 KFP05877.1 - 1.7e-74 250.2 0.1 2.5e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KFP05877.1 - 3.6e-63 212.7 0.2 9.1e-63 211.4 0.1 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain CUE PF02845.11 KFP05878.1 - 1.2e-09 37.4 0.2 3.4e-09 36.0 0.1 1.8 2 0 0 2 2 2 1 CUE domain zf-RanBP PF00641.13 KFP05878.1 - 4.7e-05 22.4 1.7 4.7e-05 22.4 1.2 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Striatin PF08232.7 KFP05879.1 - 0.0017 18.7 1.7 0.0017 18.7 1.2 1.5 2 0 0 2 2 2 1 Striatin family DUF2051 PF09738.4 KFP05879.1 - 0.0062 15.8 0.5 0.0083 15.4 0.3 1.3 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) DUF2353 PF09789.4 KFP05879.1 - 0.017 14.3 0.4 0.017 14.3 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Syntaxin PF00804.20 KFP05879.1 - 0.03 14.4 2.2 0.041 14.0 0.5 1.8 2 0 0 2 2 2 0 Syntaxin Nop25 PF09805.4 KFP05879.1 - 0.1 12.6 0.2 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4600 PF15372.1 KFP05879.1 - 0.11 12.7 1.2 0.15 12.2 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Tropomyosin_1 PF12718.2 KFP05879.1 - 0.14 11.9 2.7 0.08 12.7 0.5 1.6 2 0 0 2 2 2 0 Tropomyosin like DUF972 PF06156.8 KFP05879.1 - 0.26 11.6 3.1 0.13 12.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KFP05879.1 - 0.63 10.3 5.9 1.5 9.1 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 KFP05879.1 - 0.96 9.4 6.8 0.12 12.3 1.2 2.2 3 0 0 3 3 2 0 bZIP transcription factor HALZ PF02183.13 KFP05879.1 - 1 9.0 9.5 4.3 7.1 0.2 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper Flg_hook PF02120.11 KFP05879.1 - 1.5 8.5 6.1 9.1 6.0 4.2 2.2 1 1 0 1 1 1 0 Flagellar hook-length control protein FliK Spectrin PF00435.16 KFP05880.1 - 2.9e-177 577.1 279.3 4.7e-20 71.8 2.7 24.7 24 1 0 24 24 24 22 Spectrin repeat CH PF00307.26 KFP05880.1 - 3.1e-38 130.1 6.1 2.2e-19 69.4 0.0 6.1 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP05880.1 - 3.9e-09 36.0 0.3 6.9e-05 22.4 0.0 4.0 4 0 0 4 4 4 2 CAMSAP CH domain Claudin_2 PF13903.1 KFP05882.1 - 9.4e-12 44.9 10.6 1.1e-11 44.7 7.4 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KFP05882.1 - 0.015 15.3 3.8 0.021 14.8 2.6 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Git3 PF11710.3 KFP05882.1 - 0.017 14.7 1.0 0.019 14.5 0.7 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Claudin_3 PF06653.6 KFP05882.1 - 0.063 12.9 3.6 0.085 12.5 2.5 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like ApoO PF09769.4 KFP05882.1 - 0.14 11.8 1.4 0.2 11.3 1.0 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF3525 PF12039.3 KFP05882.1 - 0.17 10.3 0.3 0.2 10.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Yip1 PF04893.12 KFP05882.1 - 0.9 9.0 12.7 1.4 8.4 8.8 1.3 1 1 0 1 1 1 0 Yip1 domain DUF131 PF01998.12 KFP05882.1 - 0.94 8.8 3.8 1.2 8.5 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF131 DUF4064 PF13273.1 KFP05882.1 - 1.8 8.6 6.2 24 5.0 2.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF485 PF04341.7 KFP05882.1 - 2 8.1 9.8 0.084 12.5 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF485 2TM PF13239.1 KFP05882.1 - 3.8 7.6 6.7 0.14 12.2 0.5 1.6 2 0 0 2 2 2 0 2TM domain CH PF00307.26 KFP05886.1 - 6.7e-08 32.5 0.8 2.4e-07 30.7 0.1 2.2 2 1 1 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP05886.1 - 9.9e-06 25.1 0.4 3.1e-05 23.5 0.0 2.0 2 1 0 2 2 2 1 CAMSAP CH domain LANC_like PF05147.8 KFP05888.1 - 1e-63 215.1 0.0 1.2e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.8 KFP05888.1 - 0.01 15.1 0.8 1.8 7.8 0.1 2.3 1 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 KFP05888.1 - 0.093 10.9 0.0 0.48 8.6 0.0 1.7 1 1 1 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) XK-related PF09815.4 KFP05889.1 - 6.3e-59 199.6 20.1 7.4e-59 199.4 13.9 1.1 1 0 0 1 1 1 1 XK-related protein Pox_polyA_pol PF03296.8 KFP05889.1 - 0.025 14.1 0.6 0.076 12.5 0.4 1.7 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain NAD_binding_6 PF08030.7 KFP05890.1 - 3.3e-22 79.0 0.1 6.2e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFP05890.1 - 8.3e-21 73.8 0.0 1.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFP05890.1 - 3.7e-20 72.2 5.9 3.7e-20 72.2 4.1 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFP05890.1 - 1.1e-06 28.6 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFP05890.1 - 0.13 12.8 0.0 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Tctex-1 PF03645.8 KFP05891.1 - 1.9e-34 117.5 2.1 2.1e-34 117.3 1.5 1.0 1 0 0 1 1 1 1 Tctex-1 family C2 PF00168.25 KFP05892.1 - 8.7e-43 144.0 0.8 2.7e-20 72.0 0.1 2.4 2 0 0 2 2 2 2 C2 domain FYVE_2 PF02318.11 KFP05892.1 - 4.2e-19 68.5 9.9 7.2e-19 67.8 6.9 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger DUF4174 PF13778.1 KFP05893.1 - 9.2e-28 96.7 0.0 1.2e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) HYR PF02494.11 KFP05893.1 - 2.1e-26 91.7 0.0 3.7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 HYR domain Sushi PF00084.15 KFP05893.1 - 1.7e-25 89.1 24.8 1.5e-10 41.2 2.8 3.4 2 1 1 3 3 3 3 Sushi domain (SCR repeat) RCC1 PF00415.13 KFP05894.1 - 2.9e-68 225.9 15.9 3.3e-12 46.4 0.1 8.0 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFP05894.1 - 9e-39 130.2 21.5 7.3e-09 35.0 0.1 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.10 KFP05894.1 - 0.00066 19.3 0.0 6.2 6.7 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 KFP05894.1 - 0.0083 15.8 9.0 2.1 8.2 0.0 4.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KFP05894.1 - 0.074 13.2 3.2 53 4.2 0.0 4.4 4 0 0 4 4 4 0 Kelch motif OTCace PF00185.19 KFP05895.1 - 4e-47 160.0 0.0 6e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 KFP05895.1 - 7.2e-44 148.8 0.0 1.3e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Ank_2 PF12796.2 KFP05896.1 - 6.3e-19 68.1 0.6 1.4e-18 67.0 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP05896.1 - 1.2e-17 62.7 1.5 1.1e-05 24.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFP05896.1 - 1.4e-14 52.6 1.0 0.0015 18.5 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFP05896.1 - 1.2e-13 51.1 4.3 5.9e-08 33.0 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP05896.1 - 2.5e-13 49.7 3.1 2.9e-08 33.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Renin_r PF07850.9 KFP05897.1 - 9e-45 151.0 2.5 1.4e-44 150.3 1.7 1.3 1 0 0 1 1 1 1 Renin receptor-like protein Glycophorin_A PF01102.13 KFP05897.1 - 0.046 13.4 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Med14 PF08638.6 KFP05898.1 - 2e-51 174.0 0.2 5.4e-51 172.6 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 RE_SinI PF09570.5 KFP05898.1 - 0.031 13.2 0.0 0.074 12.0 0.0 1.5 1 0 0 1 1 1 0 SinI restriction endonuclease Armet PF10208.4 KFP05898.1 - 0.21 11.2 0.1 0.41 10.3 0.1 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding UCH PF00443.24 KFP05899.1 - 2.7e-60 203.7 0.7 7.4e-60 202.3 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP05899.1 - 9.5e-25 87.6 0.0 3.3e-19 69.4 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L2_C PF03947.13 KFP05901.1 - 2.4e-41 140.5 1.5 3.5e-41 140.0 1.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFP05901.1 - 1e-18 67.0 0.1 2.6e-18 65.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Guanylate_kin PF00625.16 KFP05902.1 - 4.6e-61 205.4 0.1 6.3e-61 205.0 0.1 1.2 1 0 0 1 1 1 1 Guanylate kinase SH3_2 PF07653.12 KFP05902.1 - 6.1e-13 48.0 0.0 1.1e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP05902.1 - 1.2e-08 34.2 0.9 3.1e-08 32.8 0.7 1.8 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP05902.1 - 1e-06 28.2 0.0 2.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain 7tm_1 PF00001.16 KFP05903.1 - 6.3e-23 81.2 22.3 4.3e-12 45.7 2.6 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Amino_oxidase PF01593.19 KFP05904.1 - 1.8e-65 221.8 0.0 2.1e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFP05904.1 - 1.6e-09 37.6 0.0 4.6e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFP05904.1 - 0.00015 20.8 0.2 0.084 11.7 0.1 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFP05904.1 - 0.0062 16.6 0.0 3.2 7.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFP05904.1 - 0.063 12.3 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 KFP05905.1 - 3.5e-70 237.3 0.0 4.2e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFP05905.1 - 4.2e-08 33.0 0.0 1.2e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFP05905.1 - 0.0013 17.7 0.0 0.41 9.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Cys_knot PF00007.17 KFP05906.1 - 2e-06 27.8 13.0 2.9e-06 27.3 9.0 1.2 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.10 KFP05906.1 - 4.3e-05 22.8 8.7 5e-05 22.6 6.0 1.1 1 0 0 1 1 1 1 DAN domain DUF1126 PF06565.7 KFP05907.1 - 1.9e-43 145.5 2.1 4.3e-14 51.6 0.0 3.5 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_1 PF00036.27 KFP05907.1 - 0.017 14.3 0.0 0.081 12.2 0.0 2.3 1 0 0 1 1 1 0 EF hand FUN14 PF04930.10 KFP05908.1 - 1.8e-35 121.2 3.0 2.1e-35 120.9 2.1 1.1 1 0 0 1 1 1 1 FUN14 family JmjC PF02373.17 KFP05909.1 - 3.4e-33 114.2 1.9 3.4e-33 114.2 1.3 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_1 PF00515.23 KFP05909.1 - 3.1e-30 102.5 19.4 1.6e-06 27.4 0.1 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFP05909.1 - 2.4e-24 84.7 18.8 3.8e-08 32.8 0.2 5.7 4 1 3 7 7 7 5 TPR repeat TPR_2 PF07719.12 KFP05909.1 - 1.6e-19 68.2 17.8 0.001 18.7 0.3 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFP05909.1 - 1.9e-16 59.7 11.7 0.0005 19.9 0.1 5.3 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFP05909.1 - 2e-15 55.6 3.6 6.9e-05 22.7 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFP05909.1 - 4.3e-12 46.3 6.0 0.0025 18.4 0.7 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP05909.1 - 3.8e-11 41.9 17.1 0.13 12.1 0.5 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFP05909.1 - 1.8e-07 30.3 7.4 0.77 9.7 0.1 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP05909.1 - 8.7e-07 29.0 3.7 0.56 11.0 0.0 5.7 3 2 4 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP05909.1 - 3.9e-06 26.6 4.8 0.016 15.0 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP05909.1 - 1.4e-05 25.3 9.0 0.069 13.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP05909.1 - 0.0028 17.7 22.2 0.1 12.7 1.7 4.5 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 KFP05909.1 - 0.039 13.0 14.2 0.043 12.9 1.4 3.2 2 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 KFP05909.1 - 4.5 7.9 12.1 20 5.9 0.1 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat PIP49_C PF12260.3 KFP05910.1 - 3.9e-41 140.5 0.0 7.4e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 DUF1340 PF07067.6 KFP05910.1 - 0.28 10.3 1.5 0.6 9.2 0.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1340) V-set PF07686.12 KFP05911.1 - 3.7e-12 46.1 3.6 5.5e-10 39.1 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP05911.1 - 2.2e-10 40.2 0.1 1.2e-09 37.9 0.1 2.2 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.1 KFP05911.1 - 6.2e-10 39.4 7.2 2.1e-05 24.9 1.6 4.1 2 2 2 4 4 4 3 Immunoglobulin domain I-set PF07679.11 KFP05911.1 - 1.2e-09 37.8 0.1 0.00033 20.4 0.0 2.6 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05911.1 - 4.5e-09 36.3 2.1 0.00024 21.1 0.4 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP05911.1 - 2.3e-08 34.0 3.1 0.0063 16.6 0.4 3.5 2 2 1 3 3 3 2 Immunoglobulin domain C1-set PF07654.10 KFP05911.1 - 2.5e-07 30.6 2.8 1.8e-05 24.6 0.2 3.3 3 0 0 3 3 3 1 Immunoglobulin C1-set domain Lep_receptor_Ig PF06328.6 KFP05911.1 - 0.00037 20.3 3.9 0.0056 16.5 0.0 3.3 3 1 1 4 4 4 1 Ig-like C2-type domain MLANA PF14991.1 KFP05911.1 - 0.0096 15.9 1.7 0.024 14.6 1.1 1.8 1 1 0 1 1 1 1 Protein melan-A DUF4328 PF14219.1 KFP05911.1 - 0.054 12.7 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF2987 PF11205.3 KFP05911.1 - 0.07 12.7 0.7 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) RELT PF12606.3 KFP05911.1 - 0.11 11.6 0.7 0.35 10.0 0.3 2.0 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 V-set PF07686.12 KFP05912.1 - 2.4e-08 33.8 0.0 3.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP05912.1 - 0.0043 17.1 0.1 0.0093 16.0 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP05912.1 - 0.017 15.2 0.0 0.47 10.6 0.0 2.6 1 1 0 1 1 1 0 Immunoglobulin domain V-set_CD47 PF08204.6 KFP05912.1 - 0.028 14.1 0.1 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Ig_3 PF13927.1 KFP05912.1 - 0.052 14.0 0.1 0.65 10.5 0.0 2.3 1 1 0 1 1 1 0 Immunoglobulin domain I-set PF07679.11 KFP05912.1 - 0.065 13.1 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin I-set domain DJ-1_PfpI PF01965.19 KFP05913.1 - 4e-14 52.3 0.6 5.4e-14 51.8 0.4 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family WD40 PF00400.27 KFP05914.1 - 2.2e-40 135.0 31.8 1.6e-12 46.8 0.1 10.7 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 KFP05914.1 - 2e-28 98.4 0.8 3.1e-28 97.8 0.6 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KFP05914.1 - 3.7e-08 33.3 0.9 0.11 12.1 0.0 5.1 2 1 1 5 5 5 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KFP05914.1 - 0.0051 16.4 0.4 1.1 8.9 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Utp13 PF08625.6 KFP05914.1 - 0.042 13.4 0.7 0.2 11.3 0.5 2.1 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Amidase02_C PF12123.3 KFP05914.1 - 0.1 12.2 0.2 1 9.0 0.0 2.7 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase TRAPPC10 PF12584.3 KFP05915.1 - 5.7e-23 81.0 0.0 8.1e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TRAPPC10 PF12584.3 KFP05916.1 - 5.8e-05 22.6 0.2 0.00014 21.3 0.0 1.7 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Seryl_tRNA_N PF02403.17 KFP05916.1 - 0.11 12.4 1.4 0.2 11.7 1.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Acyltransferase PF01553.16 KFP05918.1 - 4.5e-14 52.0 0.0 7.5e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase AKAP95 PF04988.7 KFP05919.1 - 3.2e-19 69.2 1.6 3.5e-19 69.1 1.1 1.0 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 KFP05919.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KFP05919.1 - 0.0039 17.3 2.0 0.0055 16.8 1.4 1.3 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KFP05919.1 - 0.0042 17.1 0.2 0.0047 17.0 0.1 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KFP05919.1 - 0.025 14.9 0.7 0.036 14.4 0.5 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3449 PF11931.3 KFP05919.1 - 0.027 13.9 0.4 0.027 13.9 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Sep15_SelM PF08806.6 KFP05919.1 - 0.13 12.0 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Sep15/SelM redox domain zf-C2HC_2 PF13913.1 KFP05919.1 - 0.18 11.5 0.8 0.51 10.0 0.5 1.8 1 1 0 1 1 1 0 zinc-finger of a C2HC-type Tis11B_N PF04553.7 KFP05920.1 - 0.053 13.6 0.2 0.074 13.2 0.1 1.3 1 0 0 1 1 1 0 Tis11B like protein, N terminus AKAP95 PF04988.7 KFP05921.1 - 1.8e-73 245.7 8.0 1.8e-73 245.7 5.5 1.6 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) DUF3505 PF12013.3 KFP05921.1 - 0.038 14.2 2.8 0.43 10.8 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) zf-C2H2_4 PF13894.1 KFP05922.1 - 4.7e-11 42.1 18.8 0.081 13.2 0.6 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-FCS PF06467.9 KFP05922.1 - 2.2e-10 39.9 2.2 0.062 12.9 0.0 4.8 5 0 0 5 5 5 3 MYM-type Zinc finger with FCS sequence motif zf-C2H2 PF00096.21 KFP05922.1 - 3.5e-10 39.6 19.9 0.039 14.3 0.3 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFP05922.1 - 7.4e-07 29.1 8.9 1.2 9.3 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding AnfO_nitrog PF09582.5 KFP05922.1 - 7.1e-06 25.3 0.0 0.31 10.1 0.0 3.8 4 0 0 4 4 4 2 Iron only nitrogenase protein AnfO (AnfO_nitrog) zf-C2H2_2 PF12756.2 KFP05922.1 - 0.00034 20.6 4.9 23 5.1 0.0 5.1 5 0 0 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KFP05922.1 - 0.00055 19.6 3.6 19 5.1 0.0 5.1 5 0 0 5 5 5 0 BED zinc finger DNA_III_psi PF03603.8 KFP05922.1 - 0.018 14.9 0.0 46 3.8 0.0 3.8 4 0 0 4 4 4 0 DNA polymerase III psi subunit BiPBP_C PF06832.7 KFP05922.1 - 0.079 12.8 0.0 28 4.7 0.0 3.1 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family zf-met PF12874.2 KFP05922.1 - 0.57 10.4 15.4 6.6 7.0 0.5 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KFP05922.1 - 3.3 7.7 13.8 33 4.5 0.1 5.0 5 0 0 5 5 5 0 Zinc ribbon domain zf-C2H2_4 PF13894.1 KFP05923.1 - 1.3e-05 25.1 21.6 0.59 10.5 0.6 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP05923.1 - 4.8e-05 23.3 27.6 0.049 13.8 0.3 5.3 5 0 0 5 5 5 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KFP05923.1 - 0.00013 22.0 23.2 0.0037 17.5 0.2 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KFP05923.1 - 0.001 19.1 12.7 1.4 9.0 0.0 4.7 3 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFP05923.1 - 0.043 13.9 10.8 0.31 11.2 1.5 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP05923.1 - 5 7.1 9.6 3.2 7.7 0.4 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger A2M_comp PF07678.9 KFP05924.1 - 1.5e-48 165.1 0.0 1.8e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 A-macroglobulin complement component Prenyltrans_2 PF13249.1 KFP05924.1 - 2.4e-05 24.6 0.0 0.011 16.1 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFP05924.1 - 0.017 15.1 0.0 0.051 13.5 0.0 1.6 1 1 1 2 2 2 0 Prenyltransferase-like WD40 PF00400.27 KFP05925.1 - 4.1e-54 178.6 26.1 3e-08 33.2 0.3 12.8 12 0 0 12 12 12 12 WD domain, G-beta repeat eIF2A PF08662.6 KFP05925.1 - 1.1e-05 25.1 0.1 0.00041 20.1 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PSII_BNR PF14870.1 KFP05925.1 - 0.039 12.9 0.0 9.9 5.0 0.0 2.5 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Hira PF07569.6 KFP05925.1 - 0.059 12.5 0.0 0.46 9.6 0.0 2.5 3 0 0 3 3 3 0 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 KFP05925.1 - 0.3 9.3 2.1 2 6.6 0.1 2.9 3 1 0 3 3 3 0 Cytochrome D1 heme domain Pkinase_Tyr PF07714.12 KFP05928.1 - 1.8e-87 292.6 0.0 2.5e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP05928.1 - 3.1e-41 141.2 0.0 4.3e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFP05928.1 - 2.4e-17 62.5 1.2 3.5e-14 52.4 0.1 2.8 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP05928.1 - 7.5e-16 58.0 0.0 3.5e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain fn3 PF00041.16 KFP05928.1 - 6.3e-15 55.0 0.2 6.8e-09 35.7 0.1 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ig_3 PF13927.1 KFP05928.1 - 1.3e-09 38.4 1.5 0.01 16.3 0.0 4.1 3 1 0 3 3 3 2 Immunoglobulin domain V-set PF07686.12 KFP05928.1 - 2.2e-06 27.5 0.0 1.5e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFP05928.1 - 2.5e-06 27.4 0.7 2.1e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 Immunoglobulin domain DUF4229 PF14012.1 KFP05928.1 - 0.035 14.0 0.2 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Kinase-like PF14531.1 KFP05928.1 - 0.042 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TMEM151 PF14857.1 KFP05929.1 - 6.7e-204 677.2 14.6 7.5e-204 677.1 10.1 1.0 1 0 0 1 1 1 1 TMEM151 family RPAP1_C PF08620.5 KFP05930.1 - 4e-26 90.6 0.4 8.8e-26 89.5 0.3 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KFP05930.1 - 2.1e-16 59.2 3.0 5.1e-16 57.9 2.1 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pkinase_Tyr PF07714.12 KFP05931.1 - 4.5e-87 291.4 0.0 6.4e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP05931.1 - 1.4e-34 119.4 0.0 2.2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gly_rich PF12810.2 KFP05931.1 - 1.2e-17 64.3 29.0 1.8e-17 63.7 20.1 1.1 1 0 0 1 1 1 1 Glycine rich protein Kinase-like PF14531.1 KFP05931.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like IPK PF03770.11 KFP05932.1 - 6.5e-42 143.4 0.0 1.5e-41 142.2 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase Sulfotransfer_2 PF03567.9 KFP05933.1 - 5.2e-44 150.8 1.9 6.1e-44 150.6 1.3 1.0 1 0 0 1 1 1 1 Sulfotransferase family Complex1_LYR PF05347.10 KFP05933.1 - 0.04 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) SPOB_ab PF14682.1 KFP05933.1 - 0.097 12.4 0.5 25 4.7 0.1 3.0 3 1 0 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal Plus-3 PF03126.13 KFP05934.1 - 1.4e-37 128.0 0.0 1.4e-37 128.0 0.0 2.3 3 0 0 3 3 3 1 Plus-3 domain EF-hand_6 PF13405.1 KFP05936.1 - 6.9e-17 59.7 0.9 4.2e-07 29.3 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 KFP05936.1 - 4.7e-16 56.7 2.3 4.7e-06 25.5 0.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFP05936.1 - 4.1e-15 55.6 2.6 2.1e-10 40.5 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP05936.1 - 7.2e-08 31.9 4.9 2.2e-05 23.9 0.3 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP05936.1 - 1.8e-07 30.2 5.2 0.01 15.1 0.2 3.4 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.4 KFP05936.1 - 1.8e-05 24.7 0.0 0.00054 19.9 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.3 KFP05936.1 - 0.00073 19.2 0.1 0.0026 17.5 0.0 2.0 2 0 0 2 2 2 1 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.2 KFP05936.1 - 0.051 13.3 1.3 1.9 8.2 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFP05936.1 - 0.12 12.3 0.1 3.9 7.4 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain SNF2_N PF00176.18 KFP05937.1 - 2.7e-71 239.8 5.7 2.7e-71 239.8 4.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 KFP05937.1 - 8.4e-51 171.6 20.8 8.4e-51 171.6 14.4 3.9 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 KFP05937.1 - 6.2e-14 51.6 0.0 1.6e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EGF PF00008.22 KFP05938.1 - 1.5e-38 130.3 126.7 2.3e-09 37.0 6.8 8.9 8 0 0 8 8 8 8 EGF-like domain MNNL PF07657.8 KFP05938.1 - 3.7e-22 78.0 0.4 3.7e-22 78.0 0.3 4.0 4 1 1 5 5 5 1 N terminus of Notch ligand hEGF PF12661.2 KFP05938.1 - 1.7e-17 62.1 85.2 0.0031 17.4 2.4 9.2 8 0 0 8 8 8 8 Human growth factor-like EGF EGF_2 PF07974.8 KFP05938.1 - 3.6e-14 52.6 144.6 0.011 15.8 6.7 8.7 8 0 0 8 8 8 8 EGF-like domain cEGF PF12662.2 KFP05938.1 - 6.4e-07 28.9 84.2 0.011 15.3 6.8 8.8 8 1 0 8 8 8 5 Complement Clr-like EGF-like Laminin_EGF PF00053.19 KFP05938.1 - 9.6e-06 25.4 105.1 0.019 14.8 6.5 8.6 2 2 6 8 8 8 4 Laminin EGF-like (Domains III and V) EGF_CA PF07645.10 KFP05938.1 - 7.5e-05 22.6 7.6 7.5e-05 22.6 5.3 9.2 4 2 4 8 8 8 3 Calcium-binding EGF domain EGF_3 PF12947.2 KFP05938.1 - 0.0002 21.2 6.9 0.0002 21.2 4.8 9.2 7 2 1 8 8 8 5 EGF domain DUF4381 PF14316.1 KFP05938.1 - 0.036 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pep3_Vps18 PF05131.9 KFP05939.1 - 5.2e-45 152.4 1.0 6.9e-44 148.8 0.0 2.6 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KFP05939.1 - 5.4e-12 45.5 18.7 6.8e-10 38.7 2.6 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KFP05939.1 - 0.00071 19.3 0.3 0.00071 19.3 0.2 2.9 4 0 0 4 4 3 1 Ring finger domain Lact-deh-memb PF09330.6 KFP05939.1 - 0.0031 16.9 1.1 0.19 11.0 0.1 2.7 2 0 0 2 2 2 1 D-lactate dehydrogenase, membrane binding Vps39_2 PF10367.4 KFP05939.1 - 0.0033 17.5 0.3 0.0033 17.5 0.2 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 KFP05939.1 - 0.0058 16.3 0.3 0.023 14.3 0.2 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFP05939.1 - 0.016 15.3 0.2 0.061 13.4 0.1 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFP05939.1 - 0.03 14.1 0.2 0.1 12.4 0.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1664 PF07889.7 KFP05939.1 - 0.044 13.5 1.0 0.1 12.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KFP05939.1 - 0.059 13.4 1.5 0.92 9.6 0.0 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.4 KFP05939.1 - 0.57 10.1 5.9 0.82 9.6 1.3 2.6 3 0 0 3 3 3 0 Zinc finger-containing protein Ras PF00071.17 KFP05940.1 - 4.2e-47 159.5 0.0 5.1e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP05940.1 - 4.3e-18 65.9 0.0 6.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP05940.1 - 1.7e-05 24.1 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP05940.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Kunitz_BPTI PF00014.18 KFP05941.1 - 1.4e-32 111.6 22.2 9.2e-19 67.3 5.2 3.6 4 0 0 4 4 3 2 Kunitz/Bovine pancreatic trypsin inhibitor domain MANEC PF07502.9 KFP05941.1 - 1.8e-26 91.9 0.6 1.8e-26 91.9 0.4 2.5 4 0 0 4 4 2 1 MANEC domain Ldl_recept_a PF00057.13 KFP05941.1 - 4.6e-09 36.0 12.6 2e-08 34.0 8.7 2.2 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A DUF912 PF06024.7 KFP05941.1 - 0.0018 18.2 0.2 0.0046 16.9 0.0 1.7 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Y_Y_Y PF07495.8 KFP05941.1 - 0.0047 16.6 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 Y_Y_Y domain PKD PF00801.15 KFP05941.1 - 0.0061 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 PKD domain REJ PF02010.10 KFP05941.1 - 0.009 14.3 0.2 0.042 12.1 0.2 1.9 1 1 0 1 1 1 1 REJ domain CSF-1 PF05337.6 KFP05941.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) Chordopox_A13L PF05961.6 KFP05941.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF1628 PF07790.6 KFP05941.1 - 0.13 13.0 0.4 0.38 11.5 0.0 1.9 3 0 0 3 3 2 0 Protein of unknown function (DUF1628) EphA2_TM PF14575.1 KFP05941.1 - 0.2 12.0 0.4 0.48 10.8 0.0 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain PP1_inhibitor PF05361.7 KFP05942.1 - 4.7e-22 78.2 4.7 5e-22 78.1 3.2 1.0 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor FYVE PF01363.16 KFP05943.1 - 0.0011 18.7 13.9 0.0011 18.7 9.6 2.8 2 1 0 2 2 2 1 FYVE zinc finger PilJ PF13675.1 KFP05943.1 - 6.9 7.0 8.7 7.7 6.8 0.1 3.3 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term UPF0444 PF15475.1 KFP05945.1 - 1e-43 147.2 11.4 1.1e-43 147.1 7.9 1.0 1 0 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Sulfotransfer_1 PF00685.22 KFP05946.1 - 2.5e-58 197.4 0.0 3e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP05946.1 - 2.2e-05 25.4 0.2 5.6e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 KFP05946.1 - 0.052 13.0 0.0 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Stf0 sulphotransferase TPT PF03151.11 KFP05947.1 - 2.5e-13 49.9 26.3 1.3e-11 44.3 6.2 2.5 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 KFP05947.1 - 2.5e-11 43.0 13.2 3.5e-11 42.5 9.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFP05947.1 - 1.8e-07 31.2 21.6 0.0002 21.4 3.9 2.7 2 2 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KFP05947.1 - 0.0089 16.2 2.7 0.0089 16.2 1.9 3.7 3 2 1 4 4 4 2 Multidrug resistance efflux transporter FAD_binding_7 PF03441.9 KFP05948.1 - 3.5e-103 344.6 0.1 4.4e-103 344.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFP05948.1 - 5.2e-26 91.3 0.0 1.5e-25 89.8 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase Peripla_BP_6 PF13458.1 KFP05948.1 - 0.033 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein PID PF00640.18 KFP05949.1 - 4.7e-33 114.1 0.3 7.7e-33 113.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) SH3_9 PF14604.1 KFP05949.1 - 6.6e-12 44.8 0.1 1.4e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP05949.1 - 1.2e-05 24.6 0.0 2.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain PID_2 PF14719.1 KFP05949.1 - 0.0021 17.7 0.1 0.0034 17.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFP05949.1 - 0.13 12.1 0.8 0.32 10.9 0.1 2.0 2 1 0 2 2 2 0 Phosphotyrosine-binding domain Pex16 PF08610.5 KFP05950.1 - 1.5e-79 267.4 3.5 1.7e-79 267.2 2.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF29 PF01724.11 KFP05950.1 - 2.5 7.9 5.9 0.51 10.1 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function DUF29 Glyco_transf_49 PF13896.1 KFP05951.1 - 1.6e-52 178.6 0.4 3.8e-41 141.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_8 PF01501.15 KFP05951.1 - 1.9e-21 76.5 0.3 3.2e-21 75.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_2 PF10111.4 KFP05951.1 - 0.0022 17.1 0.0 0.0055 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Herpes_BLRF2 PF05812.7 KFP05951.1 - 0.0035 17.1 0.1 0.0065 16.2 0.1 1.4 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein bZIP_2 PF07716.10 KFP05951.1 - 0.094 12.5 5.3 0.31 10.8 3.7 1.9 1 0 0 1 1 1 0 Basic region leucine zipper PHD PF00628.24 KFP05952.1 - 9.8e-13 47.5 6.5 2.1e-12 46.5 4.5 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KFP05952.1 - 0.0012 18.5 3.3 0.016 14.8 1.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KFP05952.1 - 0.0012 18.0 0.8 0.0032 16.7 0.6 1.8 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KFP05952.1 - 0.0013 18.4 1.1 0.0013 18.4 0.8 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.14 KFP05952.1 - 0.0065 15.9 2.0 0.019 14.5 1.4 1.8 1 0 0 1 1 1 1 AT hook motif zf-HC5HC2H PF13771.1 KFP05952.1 - 0.02 15.0 2.4 0.021 14.9 0.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain ADK_lid PF05191.9 KFP05952.1 - 0.035 13.7 2.0 0.13 11.9 1.4 2.0 1 0 0 1 1 1 0 Adenylate kinase, active site lid Seryl_tRNA_N PF02403.17 KFP05952.1 - 0.61 10.1 16.9 0.6 10.1 3.2 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-RING_2 PF13639.1 KFP05952.1 - 0.76 9.6 7.5 1.5 8.6 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain C1_3 PF07649.7 KFP05952.1 - 1.5 8.9 4.8 2.7 8.1 3.4 1.4 1 0 0 1 1 1 0 C1-like domain Erp_C PF06780.6 KFP05952.1 - 2.7 7.8 10.4 0.17 11.7 2.6 2.2 2 0 0 2 2 2 0 Erp protein C-terminus DUF2935 PF11155.3 KFP05952.1 - 4.5 7.3 7.5 3.5 7.7 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) bZIP_1 PF00170.16 KFP05954.1 - 2.4e-15 56.1 13.9 5.4e-15 55.0 9.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP05954.1 - 1.5e-09 37.5 9.2 1.5e-09 37.5 6.4 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFP05954.1 - 3e-05 24.2 10.7 6.6e-05 23.1 7.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor TPR_MLP1_2 PF07926.7 KFP05954.1 - 0.08 12.6 10.6 0.15 11.7 7.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KFP05954.1 - 0.15 11.1 6.7 0.24 10.4 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 KFP05954.1 - 0.22 11.3 11.7 0.41 10.5 8.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3552 PF12072.3 KFP05954.1 - 0.23 10.6 9.3 0.35 10.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DAGK_acc PF00609.14 KFP05956.1 - 2.9e-46 157.5 0.0 5.2e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KFP05956.1 - 1.4e-32 111.8 0.0 3.9e-32 110.4 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ank_2 PF12796.2 KFP05956.1 - 9.6e-16 57.9 0.1 1.2e-08 35.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) C1_1 PF00130.17 KFP05956.1 - 3e-12 46.0 25.8 9.4e-10 38.0 9.7 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_5 PF13857.1 KFP05956.1 - 1.6e-11 44.0 0.0 2.4e-05 24.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP05956.1 - 2.1e-11 42.9 0.0 2.4e-05 24.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 KFP05956.1 - 1.5e-10 40.3 0.0 0.00084 19.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFP05956.1 - 3e-09 37.1 0.0 6.1e-05 23.4 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PTN_MK_C PF01091.13 KFP05957.1 - 2.3e-29 101.1 8.9 2.3e-29 101.1 6.1 2.8 2 1 1 3 3 3 1 PTN/MK heparin-binding protein family, C-terminal domain PTN_MK_N PF05196.8 KFP05957.1 - 1.7e-27 95.1 19.1 1.7e-27 95.1 13.2 2.4 2 1 0 2 2 2 1 PTN/MK heparin-binding protein family, N-terminal domain 7tm_1 PF00001.16 KFP05958.1 - 1e-80 270.5 11.8 1.8e-80 269.7 8.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP05958.1 - 4.9e-07 29.1 15.7 1e-05 24.8 5.0 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx PgaD PF13994.1 KFP05958.1 - 1.2 8.6 8.1 0.071 12.5 0.3 2.5 3 0 0 3 3 3 0 PgaD-like protein WD40 PF00400.27 KFP05959.1 - 4.5e-14 51.6 2.0 2.6e-09 36.6 0.7 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 KFP05959.1 - 0.036 13.7 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DDE_Tnp_4 PF13359.1 KFP05960.1 - 1.3e-32 112.5 0.0 2e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 KFP05960.1 - 6.2e-06 25.7 0.0 5.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein ATG13 PF10033.4 KFP05961.1 - 9.6e-33 113.5 0.0 2.4e-32 112.2 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 13 RhoGAP PF00620.22 KFP05962.1 - 1.3e-44 151.4 0.2 2.7e-44 150.4 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 KFP05962.1 - 2.2e-40 137.9 5.5 3e-40 137.5 1.2 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KFP05962.1 - 7.4e-10 38.5 0.2 1.6e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain zf-H2C2_2 PF13465.1 KFP05963.1 - 1e-17 63.4 11.4 2.8e-06 27.3 0.1 3.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFP05963.1 - 6.8e-11 41.8 10.4 6.2e-05 23.1 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP05963.1 - 5e-10 38.9 12.2 0.00012 22.1 0.7 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP05963.1 - 1.1e-09 38.0 2.4 0.00043 20.3 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP05963.1 - 1.4e-07 31.1 7.8 0.01 15.7 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 KFP05963.1 - 0.00029 20.5 1.6 0.00029 20.5 1.1 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 KFP05963.1 - 0.00083 18.7 3.5 0.0025 17.2 0.1 2.4 2 1 0 2 2 2 1 zinc-ribbon domain zf-met PF12874.2 KFP05963.1 - 0.00098 19.2 6.1 0.029 14.5 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-AN1 PF01428.11 KFP05963.1 - 0.0039 17.0 4.4 4.4 7.2 0.0 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger FYDLN_acid PF09538.5 KFP05963.1 - 0.0078 16.7 1.1 3.4 8.2 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-CHY PF05495.7 KFP05963.1 - 0.0083 16.2 3.0 0.039 14.1 2.1 1.9 1 1 0 1 1 1 1 CHY zinc finger zf-ISL3 PF14690.1 KFP05963.1 - 0.033 14.2 5.4 7.2 6.7 1.8 3.1 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2321 PF10083.4 KFP05963.1 - 0.043 13.3 2.8 0.18 11.2 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-DNL PF05180.7 KFP05963.1 - 0.08 12.6 2.5 0.1 12.2 0.2 2.0 2 0 0 2 2 2 0 DNL zinc finger zf-HYPF PF07503.7 KFP05963.1 - 0.13 11.7 10.4 7 6.1 4.3 3.0 2 1 0 2 2 2 0 HypF finger C1_1 PF00130.17 KFP05963.1 - 0.13 11.9 5.2 2.1 8.1 0.7 2.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.7 KFP05963.1 - 0.14 12.2 7.0 0.14 12.2 1.7 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-LITAF-like PF10601.4 KFP05963.1 - 0.16 11.8 2.2 4.2 7.3 0.0 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-RING_5 PF14634.1 KFP05963.1 - 0.18 11.5 5.0 1.1 8.9 1.6 2.6 2 1 0 2 2 2 0 zinc-RING finger domain zf-C2H2_2 PF12756.2 KFP05963.1 - 0.2 11.8 5.0 3.9 7.6 0.1 2.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 KFP05963.1 - 0.2 12.0 3.3 4.8 7.6 1.4 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger DZR PF12773.2 KFP05963.1 - 0.27 11.0 7.4 10 6.0 0.1 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-LYAR PF08790.6 KFP05963.1 - 0.31 10.7 5.8 1.8 8.3 0.0 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger IBR PF01485.16 KFP05963.1 - 0.36 10.7 4.8 4.4 7.2 3.3 2.2 1 1 0 1 1 1 0 IBR domain GAGA PF09237.6 KFP05963.1 - 0.37 10.4 2.5 0.21 11.2 0.5 1.5 1 1 0 1 1 1 0 GAGA factor C1_4 PF07975.7 KFP05963.1 - 0.39 10.7 5.5 4.7 7.2 3.9 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain FYVE PF01363.16 KFP05963.1 - 0.43 10.4 4.9 0.32 10.8 0.9 2.1 1 1 1 2 2 2 0 FYVE zinc finger zinc_ribbon_4 PF13717.1 KFP05963.1 - 0.54 9.9 8.3 3 7.6 2.9 3.0 2 1 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 KFP05963.1 - 0.59 9.8 4.4 0.3 10.7 0.7 1.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_5 PF13719.1 KFP05963.1 - 0.6 9.7 8.3 2.8 7.5 2.9 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KFP05963.1 - 0.6 10.0 10.9 5.6 7.0 0.5 3.0 2 1 1 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.9 KFP05963.1 - 0.62 9.7 4.3 15 5.3 0.1 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid Elf1 PF05129.8 KFP05963.1 - 0.76 9.5 6.1 5.9 6.6 1.3 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF1610 PF07754.6 KFP05963.1 - 0.89 9.7 9.7 2 8.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Gin PF10764.4 KFP05963.1 - 1.2 8.8 4.0 10 5.8 0.1 2.7 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin TFIIS_C PF01096.13 KFP05963.1 - 1.3 8.7 7.1 13 5.5 0.2 3.0 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Tnp_zf-ribbon_2 PF13842.1 KFP05963.1 - 2.1 8.8 7.3 56 4.2 0.0 2.8 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Endonuclease_7 PF02945.10 KFP05963.1 - 2.4 7.9 4.9 1.7 8.4 1.9 1.8 1 1 1 2 2 2 0 Recombination endonuclease VII DUF2197 PF09963.4 KFP05963.1 - 2.5 8.1 5.7 1.7 8.6 0.0 2.5 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-MYND PF01753.13 KFP05963.1 - 3 7.7 6.8 42 4.1 4.7 2.7 1 1 1 2 2 2 0 MYND finger RRN7 PF11781.3 KFP05963.1 - 3.1 7.3 5.7 6.6 6.3 0.1 2.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 KFP05963.1 - 3.1 7.1 7.2 17 4.8 1.2 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding zf-trcl PF13451.1 KFP05963.1 - 3.3 7.4 10.3 66 3.2 0.1 3.0 2 1 0 2 2 2 0 Probable zinc-binding domain CpXC PF14353.1 KFP05963.1 - 3.4 7.6 7.4 1.2 9.0 0.2 2.8 1 1 2 3 3 3 0 CpXC protein XPA_N PF01286.13 KFP05963.1 - 6.2 6.5 6.0 18 5.1 0.1 3.0 3 0 0 3 3 3 0 XPA protein N-terminal Zn_Tnp_IS1 PF03811.8 KFP05963.1 - 6.7 6.3 12.9 3.6 7.1 0.2 2.9 2 1 0 2 2 2 0 InsA N-terminal domain Ogr_Delta PF04606.7 KFP05963.1 - 6.9 6.4 6.5 13 5.5 1.5 2.5 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Fer4_4 PF12800.2 KFP05963.1 - 8.4 7.0 6.9 36 5.0 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain LIM PF00412.17 KFP05963.1 - 9.1 6.4 9.4 34 4.6 0.1 2.9 1 1 2 3 3 3 0 LIM domain zf-ribbon_3 PF13248.1 KFP05963.1 - 9.8 5.5 8.7 7.6 5.8 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain MMS1_N PF10433.4 KFP05964.1 - 1.9e-95 319.9 0.1 6.4e-95 318.1 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KFP05964.1 - 1.5e-83 280.6 0.1 1.7e-82 277.1 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region Beta_propel PF09826.4 KFP05964.1 - 0.017 13.4 0.0 0.027 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta propeller domain Dak2 PF02734.12 KFP05965.1 - 3.6e-48 163.5 2.8 5.5e-48 162.9 1.9 1.3 1 0 0 1 1 1 1 DAK2 domain Dak1 PF02733.12 KFP05965.1 - 5.3e-19 67.9 0.7 1.3e-09 37.0 0.0 2.9 2 1 1 3 3 3 2 Dak1 domain Cytochrom_B561 PF03188.11 KFP05966.1 - 4.3e-43 146.4 7.4 4.3e-43 146.4 5.1 1.7 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 PepSY_TM_3 PF13706.1 KFP05966.1 - 0.017 14.5 1.3 0.017 14.5 0.9 3.4 4 0 0 4 4 4 0 PepSY-associated TM helix Cytochrom_B_N PF00033.14 KFP05966.1 - 0.28 10.5 23.4 0.042 13.1 10.5 2.6 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 KFP05966.1 - 3.5 6.9 23.6 32 3.8 9.9 3.0 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4079 PF13301.1 KFP05966.1 - 4.5 7.2 15.7 0.23 11.4 4.5 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4079) DUF2427 PF10348.4 KFP05966.1 - 7.3 6.2 10.7 0.59 9.7 0.8 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) TMEM138 PF14935.1 KFP05967.1 - 7.9e-37 126.2 1.1 8.8e-37 126.1 0.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 138 Transmemb_17 PF09799.4 KFP05968.1 - 1.4e-13 51.0 1.0 1.5e-13 50.9 0.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein InaF-motif PF15018.1 KFP05968.1 - 0.16 11.4 3.9 0.34 10.3 2.7 1.6 1 1 0 1 1 1 0 TRP-interacting helix RRM_1 PF00076.17 KFP05969.1 - 1.7e-07 30.7 0.0 4.3e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP05969.1 - 5.9e-05 22.9 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.2 KFP05969.1 - 2.5 8.7 34.4 0.52 10.8 21.4 1.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1509 PF07420.6 KFP05969.1 - 7.8 5.6 21.1 0.023 14.0 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1509) Sdh5 PF03937.11 KFP05970.1 - 3.2e-11 42.7 0.1 4.4e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase cNMP_binding PF00027.24 KFP05971.1 - 1.2e-56 188.5 0.0 1.7e-17 62.9 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KFP05971.1 - 8.6e-23 81.3 0.1 1.8e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PKD_channel PF08016.7 KFP05972.1 - 9.6e-11 40.7 15.8 1.9e-10 39.7 10.9 1.5 1 0 0 1 1 1 1 Polycystin cation channel GPP34 PF05719.6 KFP05973.1 - 1.3e-52 178.8 0.5 1.5e-52 178.6 0.4 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M15_2 PF05951.8 KFP05973.1 - 0.014 14.8 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Lipase_GDSL_2 PF13472.1 KFP05974.1 - 6.7e-08 32.8 0.0 1.4e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Mito_fiss_reg PF05308.6 KFP05974.1 - 0.088 12.1 3.4 0.17 11.2 2.3 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator Bcr-Abl_Oligo PF09036.5 KFP05974.1 - 0.33 10.9 2.0 12 5.9 0.2 2.7 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain RVT_1 PF00078.22 KFP05975.1 - 0.0058 16.0 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KFP05976.1 - 0.055 12.8 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CotJB PF12652.2 KFP05976.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 CotJB protein dUTPase PF00692.14 KFP05977.1 - 1.3e-18 66.6 0.4 2.1e-18 66.0 0.3 1.3 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP05977.1 - 0.00011 22.0 0.1 0.00024 20.9 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KFP05977.1 - 0.061 13.1 0.2 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PC4 PF02229.11 KFP05978.1 - 1.2e-23 82.0 0.3 2.3e-23 81.1 0.2 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) QLQ PF08880.6 KFP05978.1 - 0.016 14.5 0.2 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 QLQ SR-25 PF10500.4 KFP05978.1 - 0.052 13.0 11.7 0.067 12.6 8.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpc4 PF05132.9 KFP05978.1 - 0.23 11.4 3.2 0.28 11.1 2.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.7 KFP05978.1 - 1.7 8.4 5.5 2.1 8.1 3.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 dUTPase PF00692.14 KFP05979.1 - 7.8e-19 67.4 0.2 1.1e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP05979.1 - 0.058 13.3 0.2 0.24 11.3 0.0 2.1 2 1 0 2 2 2 0 Retroviral aspartyl protease TGF_beta PF00019.15 KFP05980.1 - 6.3e-29 100.3 2.2 6.3e-29 100.3 1.5 1.6 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP05980.1 - 2e-21 76.4 0.2 2.6e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 TGF-beta propeptide Xylanase PF13201.1 KFP05981.1 - 0.098 11.4 0.1 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 Putative glycoside hydrolase xylanase HCMV_UL139 PF12507.3 KFP05981.1 - 0.33 11.1 2.8 7.5 6.7 0.1 2.1 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Jiv90 PF14901.1 KFP05982.1 - 1.5e-25 89.0 0.0 1.6e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone zf-NADH-PPase PF09297.6 KFP05982.1 - 0.14 11.6 0.7 0.25 10.8 0.5 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain G-alpha PF00503.15 KFP05984.1 - 4e-87 292.4 0.5 4.8e-87 292.1 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP05984.1 - 2.7e-10 39.7 0.2 1.2e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KFP05984.1 - 0.0039 17.6 0.2 0.71 10.3 0.1 2.4 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KFP05984.1 - 0.043 13.3 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFP05984.1 - 0.061 13.2 0.0 0.99 9.3 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFP05984.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 KFP05984.1 - 0.5 9.4 2.2 6 5.9 0.2 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region HIT PF01230.18 KFP05985.1 - 1.7e-10 41.2 0.0 1.9e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 HIT domain dUTPase PF00692.14 KFP05986.1 - 2.9e-17 62.3 0.0 3.6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP05986.1 - 0.0031 17.3 0.1 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease RVT_1 PF00078.22 KFP05987.1 - 4.3e-29 101.3 0.0 5.6e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KFP05988.1 - 3.3e-27 94.9 0.1 5.3e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 KFP05988.1 - 2.1e-12 46.2 0.2 3.5e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.19 KFP05988.1 - 2.2e-11 44.2 1.1 3.9e-11 43.4 0.2 1.8 2 0 0 2 2 2 1 RNase H DDE_Tnp_IS240 PF13610.1 KFP05988.1 - 3.5e-06 27.0 0.0 6.7e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 DDE domain rve_3 PF13683.1 KFP05988.1 - 0.02 14.4 0.0 0.055 13.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DUF4577 PF15145.1 KFP05988.1 - 0.058 13.2 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) TLV_coat PF00429.14 KFP05989.1 - 0.087 11.2 0.1 0.099 11.0 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) CUB PF00431.15 KFP05992.1 - 3.4e-20 72.1 0.0 5.2e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 CUB domain PDGF PF00341.12 KFP05992.1 - 1.9e-09 37.5 4.1 3.3e-09 36.7 2.9 1.4 1 0 0 1 1 1 1 PDGF/VEGF domain Dynein_heavy PF03028.10 KFP05993.1 - 1.1e-130 436.9 0.0 1.1e-130 436.9 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KFP05993.1 - 1.5e-111 372.7 2.4 1.5e-111 372.7 1.6 4.8 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KFP05993.1 - 1.7e-82 276.4 0.0 8.7e-82 274.1 0.0 2.2 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KFP05993.1 - 3.5e-44 150.3 0.3 1.5e-43 148.2 0.1 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 DHC_N1 PF08385.7 KFP05993.1 - 1.2e-43 149.4 0.9 1.2e-43 149.4 0.6 4.7 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.9 KFP05993.1 - 3.7e-37 127.1 0.0 9.8e-23 80.4 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) MT PF12777.2 KFP05993.1 - 8.4e-27 93.8 14.1 1.6e-26 92.9 9.1 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 KFP05993.1 - 1.4e-26 93.1 0.0 7.5e-26 90.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 KFP05993.1 - 5.5e-18 65.0 0.9 1.9e-17 63.2 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KFP05993.1 - 4.4e-10 39.7 3.1 0.0012 18.9 0.0 6.1 5 0 0 5 5 5 2 AAA domain AAA_17 PF13207.1 KFP05993.1 - 6.6e-06 26.9 0.0 0.017 15.8 0.0 4.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KFP05993.1 - 1.1e-05 24.6 0.4 0.0028 16.8 0.0 3.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA PF00004.24 KFP05993.1 - 4.7e-05 23.6 5.7 0.56 10.4 0.0 5.5 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFP05993.1 - 0.00037 20.5 26.2 0.22 11.4 0.0 7.9 8 1 1 9 9 9 3 AAA ATPase domain ABC_tran PF00005.22 KFP05993.1 - 0.00046 20.4 11.8 0.036 14.3 0.0 5.6 6 0 0 6 6 5 2 ABC transporter AAA_28 PF13521.1 KFP05993.1 - 0.002 18.1 0.2 0.1 12.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain IncA PF04156.9 KFP05993.1 - 0.002 17.7 8.1 0.002 17.7 5.6 7.1 6 0 0 6 6 5 2 IncA protein RNA_helicase PF00910.17 KFP05993.1 - 0.0021 18.1 0.4 1.5 9.0 0.0 4.3 4 0 0 4 4 3 1 RNA helicase AAA_18 PF13238.1 KFP05993.1 - 0.0026 18.0 0.7 2.3 8.5 0.0 5.4 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KFP05993.1 - 0.0072 15.8 0.1 0.71 9.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KFP05993.1 - 0.008 16.0 1.7 0.072 12.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KFP05993.1 - 0.56 9.9 0.4 15 5.4 0.0 3.1 2 0 0 2 2 2 0 Part of AAA domain Reo_sigmaC PF04582.7 KFP05993.1 - 7.5 5.6 7.2 1.1 8.4 0.5 2.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Cullin_binding PF03556.10 KFP05994.1 - 2.8e-32 111.3 5.6 3.8e-32 110.8 3.9 1.2 1 0 0 1 1 1 1 Cullin binding Peptidase_M10 PF00413.19 KFP05995.1 - 3e-65 218.6 0.0 5.1e-65 217.9 0.0 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFP05995.1 - 2.9e-41 138.9 4.4 9.3e-14 50.8 0.0 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFP05995.1 - 1e-11 44.6 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFP05995.1 - 0.012 15.0 0.1 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFP05995.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFP05995.1 - 0.056 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFP05995.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 KFP05995.1 - 0.18 11.2 0.0 1.9 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Reprolysin_4 PF13583.1 KFP05995.1 - 0.22 11.0 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFP05996.1 - 6.8e-61 204.5 0.1 1.5e-60 203.3 0.0 1.6 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.14 KFP05996.1 - 1.7e-44 149.2 9.9 3.6e-15 55.4 0.1 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFP05996.1 - 2.6e-12 46.5 0.0 4.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFP05996.1 - 0.005 16.2 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFP05996.1 - 0.0069 16.9 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFP05996.1 - 0.039 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KFP05997.1 - 5.1e-60 201.6 0.1 1.1e-59 200.6 0.0 1.6 2 0 0 2 2 2 1 Matrixin Hemopexin PF00045.14 KFP05997.1 - 7.7e-36 121.5 9.7 1.4e-12 47.1 0.4 4.4 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFP05997.1 - 8.4e-10 38.4 0.9 7.8e-09 35.3 0.0 2.6 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 KFP05997.1 - 7.5e-07 29.7 0.0 2.9e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 KFP05997.1 - 0.00035 20.0 0.6 0.67 9.3 0.1 2.6 3 0 0 3 3 3 2 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 KFP05997.1 - 0.00041 20.3 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFP05997.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP05997.1 - 0.0022 18.0 0.0 0.007 16.4 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 KFP05997.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 DUF3152 PF11350.3 KFP05997.1 - 0.028 13.9 0.3 0.17 11.3 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3152) Peptidase_M10 PF00413.19 KFP05998.1 - 2.9e-60 202.4 0.0 4.7e-60 201.7 0.0 1.3 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFP05998.1 - 2.2e-43 145.7 5.6 6.9e-13 48.1 0.0 4.3 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFP05998.1 - 1.8e-15 56.6 0.6 6.5e-15 54.8 0.1 2.1 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFP05998.1 - 0.0018 17.6 0.2 0.44 9.9 0.0 2.3 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFP05998.1 - 0.011 16.2 0.3 0.022 15.2 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFP05998.1 - 0.02 14.8 0.1 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFP05998.1 - 0.024 14.6 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 KFP05998.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Reprolysin_4 PF13583.1 KFP05998.1 - 0.056 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KFP05998.1 - 0.087 11.6 0.1 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.3 KFP05998.1 - 0.13 10.6 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.19 KFP05999.1 - 5.5e-61 204.8 0.0 8e-61 204.2 0.0 1.2 1 0 0 1 1 1 1 Matrixin PG_binding_1 PF01471.13 KFP05999.1 - 2.2e-11 43.5 0.0 4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFP05999.1 - 0.00039 19.8 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Reprolysin_3 PF13582.1 KFP05999.1 - 0.011 16.2 0.8 0.018 15.5 0.6 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFP05999.1 - 0.029 14.2 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFP05999.1 - 0.038 13.5 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP05999.1 - 0.13 12.3 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MGC-24 PF05283.6 KFP06000.1 - 8.1e-07 29.0 16.2 1e-06 28.6 11.2 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Alpha_GJ PF03229.8 KFP06000.1 - 0.37 11.1 5.4 0.45 10.8 3.7 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Mucin PF01456.12 KFP06000.1 - 5.4 6.7 21.9 6.9 6.4 15.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein BIR PF00653.16 KFP06001.1 - 9.6e-68 224.5 13.7 3.7e-23 81.7 0.4 3.8 4 0 0 4 4 4 3 Inhibitor of Apoptosis domain CARD PF00619.16 KFP06001.1 - 1.2e-21 76.3 0.4 2.7e-21 75.1 0.3 1.7 1 0 0 1 1 1 1 Caspase recruitment domain zf-C3HC4_3 PF13920.1 KFP06001.1 - 7.8e-15 54.2 8.5 7.8e-15 54.2 5.9 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP06001.1 - 5.1e-06 26.4 12.1 5.1e-06 26.4 8.4 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP06001.1 - 0.0026 17.4 8.7 0.0026 17.4 6.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFP06001.1 - 0.0051 16.3 3.7 0.0051 16.3 2.5 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF2039 PF10217.4 KFP06001.1 - 0.23 11.4 4.5 0.82 9.7 3.1 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RNA_pol_N PF01194.12 KFP06001.1 - 0.61 10.1 6.4 9.8 6.2 0.0 3.4 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit WW PF00397.21 KFP06002.1 - 1.3e-09 37.7 0.3 2.9e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 WW domain DUF4498 PF14926.1 KFP06003.1 - 1.5e-96 322.2 3.8 1.7e-96 322.1 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) K1377 PF15352.1 KFP06004.1 - 1.1e-212 708.8 52.3 1.4e-212 708.4 36.3 1.1 1 0 0 1 1 1 1 Susceptibility to monomelic amyotrophy Prog_receptor PF02161.10 KFP06005.1 - 1.2e-35 123.3 11.4 1.5e-35 123.1 7.9 1.1 1 0 0 1 1 1 1 Progesterone receptor zf-C4 PF00105.13 KFP06005.1 - 1.3e-26 92.6 15.6 1.3e-26 92.6 10.8 1.5 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFP06005.1 - 4.3e-26 91.2 6.9 6.4e-26 90.7 4.8 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor RhoGAP PF00620.22 KFP06006.1 - 9.7e-41 138.9 0.3 6.3e-40 136.2 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.1 KFP06006.1 - 3.8e-09 35.9 0.0 9e-09 34.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP06006.1 - 1.2e-05 24.6 0.0 2.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP06006.1 - 0.12 11.9 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain PH_11 PF15413.1 KFP06006.1 - 0.12 12.6 1.7 2.9 8.1 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain OmpH PF03938.9 KFP06006.1 - 1 9.2 7.3 3 7.7 5.1 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Phe_tRNA-synt_N PF02912.13 KFP06007.1 - 0.13 12.0 0.2 5 6.9 0.0 2.8 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF4211 PF13926.1 KFP06009.1 - 9.8e-33 112.7 1.8 9.8e-33 112.7 1.2 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) DUF4196 PF13846.1 KFP06009.1 - 1.3e-07 31.8 0.6 1.3e-07 31.8 0.4 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4196) DUF2185 PF09951.4 KFP06009.1 - 0.027 14.2 0.7 0.29 10.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) Myotub-related PF06602.9 KFP06012.1 - 2.6e-147 490.2 0.0 3.5e-147 489.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 KFP06012.1 - 2.7e-11 42.7 0.0 5.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 KFP06012.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP06012.1 - 0.0026 17.3 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP06012.1 - 0.0057 16.9 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family NYD-SP28_assoc PF14775.1 KFP06012.1 - 0.022 14.4 3.7 0.52 10.0 0.5 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain 3-PAP PF12578.3 KFP06012.1 - 0.075 12.8 0.4 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein Cep57_CLD PF14073.1 KFP06013.1 - 2.6e-64 216.3 37.2 2.6e-64 216.3 25.8 2.4 2 1 0 2 2 2 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.8 KFP06013.1 - 4.6e-20 71.3 6.4 4.6e-20 71.3 4.5 4.2 3 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 KFP06013.1 - 0.0017 17.9 6.4 0.0017 17.9 4.5 3.3 2 1 1 3 3 3 2 IncA protein Lebercilin PF15619.1 KFP06013.1 - 0.0026 17.1 6.5 0.0026 17.1 4.5 3.6 2 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.3 KFP06013.1 - 0.0088 15.7 11.2 0.0088 15.7 7.8 4.0 2 2 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF3708 PF12501.3 KFP06013.1 - 0.32 10.8 1.2 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter TMCO5 PF14992.1 KFP06013.1 - 3 6.9 43.3 0.89 8.6 22.0 2.6 2 1 0 2 2 2 0 TMCO5 family Flagellin_N PF00669.15 KFP06013.1 - 4.8 6.9 11.3 2.4 7.9 0.9 3.4 3 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region DUF3552 PF12072.3 KFP06014.1 - 0.011 14.9 13.4 0.011 14.9 9.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Myosin_HC-like PF07058.6 KFP06014.1 - 0.28 10.2 10.6 1.2 8.2 5.4 2.3 2 1 0 2 2 2 0 Myosin II heavy chain-like OmpH PF03938.9 KFP06014.1 - 0.33 10.8 11.3 0.89 9.4 7.8 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Metal_resist PF13801.1 KFP06014.1 - 0.67 9.9 7.3 2.3 8.2 1.6 2.4 2 0 0 2 2 2 0 Heavy-metal resistance ATP-synt_B PF00430.13 KFP06014.1 - 0.83 9.4 10.1 0.22 11.3 4.6 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Innate_immun PF12782.2 KFP06014.1 - 1.8 7.7 15.7 3.2 6.8 10.9 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF2614 PF11023.3 KFP06014.1 - 3.1 7.6 8.4 1.9 8.3 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) GAS PF13851.1 KFP06014.1 - 6.1 5.9 22.5 0.15 11.2 8.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cwf_Cwc_15 PF04889.7 KFP06016.1 - 2.1e-75 253.6 24.3 5.2e-75 252.3 16.8 1.6 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.8 KFP06016.1 - 0.21 9.3 11.0 0.24 9.1 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Corona_nucleoca PF00937.13 KFP06016.1 - 0.84 8.5 7.2 1 8.2 5.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Angiomotin_C PF12240.3 KFP06017.1 - 2.3e-91 304.8 30.7 7.3e-91 303.2 9.7 3.7 2 1 0 2 2 2 2 Angiomotin C terminal NPV_P10 PF05531.7 KFP06017.1 - 0.82 9.9 4.6 0.81 9.9 1.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.1 KFP06017.1 - 1.7 8.0 41.3 2.4 7.5 21.6 3.4 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.4 KFP06017.1 - 7.3 6.7 23.9 1.2 9.3 6.3 3.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ank_2 PF12796.2 KFP06018.1 - 1.7e-35 121.2 6.4 9.9e-22 77.0 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP06018.1 - 2e-34 115.6 4.8 1.9e-13 49.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KFP06018.1 - 9.9e-33 111.9 5.8 1.1e-14 54.4 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP06018.1 - 1.5e-25 86.6 3.8 4.2e-07 29.5 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFP06018.1 - 2.5e-25 87.9 12.3 1.4e-10 41.0 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Tcell_CD4_Cterm PF12104.3 KFP06018.1 - 0.07 12.7 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region PBP1_TM PF14812.1 KFP06018.1 - 6.5 7.1 9.6 2.3 8.6 1.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mre11_DNA_bind PF04152.9 KFP06019.1 - 2.8e-47 160.8 0.5 2.8e-47 160.8 0.4 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KFP06019.1 - 6.2e-28 97.5 3.4 9e-28 97.0 2.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFP06019.1 - 6.8e-07 29.2 0.0 2.4e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 7tm_1 PF00001.16 KFP06020.1 - 1.2e-59 201.5 25.3 1.9e-59 200.9 17.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06020.1 - 3.5e-18 65.7 24.7 4.3e-18 65.3 17.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2109 PF09882.4 KFP06020.1 - 0.68 9.9 7.4 0.44 10.5 1.3 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Innexin PF00876.13 KFP06021.1 - 4.4e-14 52.3 6.1 8.8e-14 51.3 4.2 1.6 1 1 0 1 1 1 1 Innexin DUF3733 PF12534.3 KFP06021.1 - 0.036 13.3 0.2 0.036 13.3 0.2 2.2 3 0 0 3 3 3 0 Leucine-rich repeat containing protein 8 L6_membrane PF05805.7 KFP06022.1 - 3.4e-56 189.9 16.4 3.9e-56 189.7 11.4 1.0 1 0 0 1 1 1 1 L6 membrane protein V-set PF07686.12 KFP06023.1 - 7.4e-08 32.2 0.2 1.1e-07 31.7 0.2 1.2 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP06023.1 - 0.00045 20.0 0.2 0.0022 17.8 0.2 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Receptor_2B4 PF11465.3 KFP06023.1 - 0.0005 19.9 0.1 0.00085 19.2 0.1 1.3 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 DUF3754 PF12576.3 KFP06023.1 - 0.023 14.3 0.4 1.3 8.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Med17 PF10156.4 KFP06024.1 - 3.8e-96 322.1 2.7 5e-96 321.7 1.9 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DUF1907 PF08925.6 KFP06025.1 - 6.4e-128 425.7 0.0 7.3e-128 425.5 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) TAF1D PF15333.1 KFP06026.1 - 2.7e-54 184.2 24.1 7.3e-51 173.0 16.7 3.0 1 1 0 1 1 1 1 TATA box-binding protein-associated factor 1D ALMS_motif PF15309.1 KFP06027.1 - 3.1e-12 46.5 17.8 3.1e-12 46.5 12.3 1.5 2 0 0 2 2 2 1 ALMS motif Snapin_Pallidin PF14712.1 KFP06029.1 - 0.033 14.5 4.4 0.037 14.3 3.0 1.2 1 0 0 1 1 1 0 Snapin/Pallidin RAP1 PF07218.6 KFP06030.1 - 0.036 12.1 0.3 0.038 12.0 0.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF763 PF05559.6 KFP06030.1 - 0.25 10.2 1.1 0.29 10.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) ABC_tran_2 PF12848.2 KFP06030.1 - 0.25 11.1 7.8 0.51 10.2 5.4 1.4 1 0 0 1 1 1 0 ABC transporter eIF3_subunit PF08597.5 KFP06030.1 - 0.53 9.8 6.8 0.86 9.1 4.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit APG6 PF04111.7 KFP06030.1 - 8.5 5.3 8.5 12 4.8 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CPSase_L_D3 PF02787.14 KFP06031.1 - 0.00067 19.4 0.4 0.00097 18.8 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF1690 PF07956.6 KFP06031.1 - 0.1 12.6 5.1 0.12 12.3 3.3 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) FUSC-like PF12805.2 KFP06031.1 - 0.14 11.0 5.4 0.16 10.8 3.7 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Phage_GPO PF05929.6 KFP06031.1 - 0.18 11.0 4.2 0.21 10.8 2.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase vATP-synt_E PF01991.13 KFP06031.1 - 0.4 9.9 11.7 0.44 9.7 8.1 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit MRP-S26 PF14943.1 KFP06031.1 - 3.1 7.3 14.5 2 7.9 8.7 1.6 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 DUF4519 PF15012.1 KFP06032.1 - 1.1e-27 95.6 5.0 1.2e-27 95.5 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF4448 PF14610.1 KFP06032.1 - 3.4e-05 23.4 0.1 3.7e-05 23.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 KFP06032.1 - 0.00037 20.4 0.0 0.00038 20.4 0.0 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3899 PF13038.1 KFP06032.1 - 0.00042 20.4 0.0 0.00044 20.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) DUF2232 PF09991.4 KFP06032.1 - 0.0019 17.2 0.0 0.0021 17.1 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) Vma12 PF11712.3 KFP06032.1 - 0.005 16.5 0.0 0.0054 16.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3753 PF12575.3 KFP06032.1 - 0.015 15.0 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF106 PF01956.11 KFP06032.1 - 0.024 14.1 0.1 0.026 14.0 0.0 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 FTCD_C PF04961.7 KFP06032.1 - 0.034 13.5 0.1 0.034 13.5 0.1 1.0 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF3357 PF11837.3 KFP06032.1 - 0.037 13.8 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3290 PF11694.3 KFP06032.1 - 0.06 13.0 0.3 0.076 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2077 PF09850.4 KFP06032.1 - 0.063 12.6 0.0 0.069 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) AHSP PF09236.5 KFP06032.1 - 0.069 13.3 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein DUF4064 PF13273.1 KFP06032.1 - 0.076 13.1 0.0 0.085 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) CoatB PF10389.4 KFP06032.1 - 0.082 12.7 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage coat protein B DUF2208 PF09973.4 KFP06032.1 - 0.084 12.0 0.0 0.084 12.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) CD34_antigen PF06365.7 KFP06032.1 - 0.099 12.2 0.0 0.099 12.2 0.0 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family ODV-E18 PF10717.4 KFP06032.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RskA PF10099.4 KFP06032.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA UPF0233 PF06781.7 KFP06032.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2116 PF09889.4 KFP06032.1 - 1.5 8.6 3.6 2.3 8.0 2.5 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Protocadherin PF08374.6 KFP06032.1 - 2.6 7.6 4.8 3.3 7.3 3.3 1.3 1 1 0 1 1 1 0 Protocadherin Phage_Treg PF04761.7 KFP06033.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator 7tm_1 PF00001.16 KFP06034.1 - 2.9e-43 147.8 25.6 3.4e-43 147.6 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP06034.1 - 1.9e-05 23.9 23.5 2.8e-05 23.3 16.3 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx OTOS PF15182.1 KFP06034.1 - 0.084 12.5 0.0 0.3 10.7 0.0 2.0 1 0 0 1 1 1 0 Otospiralin Git3 PF11710.3 KFP06034.1 - 0.73 9.3 24.7 0.27 10.7 11.2 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Cadherin PF00028.12 KFP06035.1 - 0 1178.0 67.5 1.1e-22 80.1 0.0 25.6 25 0 0 25 25 25 25 Cadherin domain Laminin_G_2 PF02210.19 KFP06035.1 - 1e-22 80.5 0.5 2.1e-21 76.3 0.1 3.0 3 0 0 3 3 3 1 Laminin G domain Laminin_G_1 PF00054.18 KFP06035.1 - 8.4e-17 61.4 0.0 6.1e-16 58.6 0.0 2.6 2 0 0 2 2 2 1 Laminin G domain Cadherin_2 PF08266.7 KFP06035.1 - 1.1e-15 56.9 0.0 0.8 9.3 0.0 11.8 13 0 0 13 13 13 4 Cadherin-like EGF PF00008.22 KFP06035.1 - 3.3e-13 49.3 53.7 0.00012 21.9 5.8 4.6 4 0 0 4 4 4 4 EGF-like domain EGF_CA PF07645.10 KFP06035.1 - 2.8e-05 24.0 10.7 2.8e-05 24.0 7.4 4.6 3 1 1 4 4 4 1 Calcium-binding EGF domain MLANA PF14991.1 KFP06035.1 - 0.0022 17.9 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein melan-A CHORD PF04968.7 KFP06036.1 - 1.3e-47 159.8 20.6 8.9e-29 99.5 4.1 2.8 4 0 0 4 4 4 2 CHORD CS PF04969.11 KFP06036.1 - 2.6e-17 63.1 0.2 6.6e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 CS domain DUF2733 PF10813.3 KFP06036.1 - 0.037 13.5 5.9 1.8 8.2 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) TFR_dimer PF04253.10 KFP06037.1 - 5.2e-41 139.1 0.0 1.7e-40 137.4 0.0 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFP06037.1 - 2.6e-15 56.6 0.0 6.3e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFP06037.1 - 4.7e-12 45.4 0.0 1.1e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 PA domain IQ-like PF15157.1 KFP06037.1 - 0.00028 21.0 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 IQ-like TFR_dimer PF04253.10 KFP06038.1 - 3.3e-40 136.5 0.1 7.1e-40 135.4 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFP06038.1 - 3e-15 56.4 0.0 7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFP06038.1 - 6e-12 45.1 0.0 1.7e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 PA domain NAD_binding_6 PF08030.7 KFP06039.1 - 1.2e-22 80.5 0.0 4.2e-21 75.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KFP06039.1 - 2e-18 66.6 4.4 2e-18 66.6 3.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFP06039.1 - 1.4e-15 57.0 0.0 2.9e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KFP06039.1 - 0.00045 20.7 0.0 0.052 14.1 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cytochrom_B_N PF00033.14 KFP06039.1 - 0.014 14.7 0.6 0.68 9.2 0.1 2.4 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 KFP06039.1 - 0.029 13.7 3.1 1.9 7.8 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 FAD_binding_6 PF00970.19 KFP06039.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Tyrosinase PF00264.15 KFP06040.1 - 3.2e-42 145.2 1.2 5.1e-42 144.5 0.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Laminin_EGF PF00053.19 KFP06040.1 - 0.0013 18.5 3.4 0.0013 18.5 2.3 2.3 2 0 0 2 2 2 1 Laminin EGF-like (Domains III and V) Ldr_toxin PF13940.1 KFP06040.1 - 0.0043 16.7 1.6 0.011 15.4 1.1 1.7 1 0 0 1 1 1 1 Toxin Ldr, type I toxin-antitoxin system SKG6 PF08693.5 KFP06040.1 - 0.19 11.0 0.3 0.34 10.2 0.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain 7tm_3 PF00003.17 KFP06041.1 - 9e-74 247.7 25.0 1.3e-73 247.2 17.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 KFP06041.1 - 2.7e-46 157.9 0.0 3.9e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region GluR_Homer-bdg PF10606.4 KFP06041.1 - 5.7e-25 86.9 11.7 2.1e-24 85.1 8.1 2.1 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.9 KFP06041.1 - 1.9e-18 65.9 13.5 3.6e-18 65.0 9.4 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFP06041.1 - 0.0014 18.0 0.0 0.0042 16.4 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein Ras PF00071.17 KFP06042.1 - 4.7e-42 143.1 0.0 5.6e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06042.1 - 2.3e-18 66.8 0.0 3.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06042.1 - 4.3e-10 39.1 0.1 4.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP06042.1 - 1.8e-07 30.5 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP06042.1 - 0.00056 19.3 0.1 0.015 14.7 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFP06042.1 - 0.005 16.9 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KFP06042.1 - 0.0096 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KFP06042.1 - 0.027 13.9 0.0 0.54 9.7 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KFP06042.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Tim17 PF02466.14 KFP06044.1 - 1.4e-07 31.5 0.9 3.3e-07 30.4 0.1 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF4010 PF13194.1 KFP06044.1 - 0.044 13.0 0.6 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Frizzled PF01534.12 KFP06045.1 - 1.8e-135 450.9 24.2 4.9e-133 442.9 16.7 2.0 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFP06045.1 - 4.8e-18 65.6 2.6 9e-18 64.7 1.8 1.5 1 0 0 1 1 1 1 Fz domain TctB PF07331.6 KFP06045.1 - 0.028 14.0 0.3 0.028 14.0 0.2 3.3 2 2 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family Ndc1_Nup PF09531.5 KFP06045.1 - 2.1 6.6 10.8 0.019 13.4 1.8 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Trypsin PF00089.21 KFP06046.1 - 3.9e-11 42.9 0.1 3e-10 40.0 0.1 2.3 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFP06046.1 - 1.8e-07 31.1 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain FB_lectin PF07367.6 KFP06046.1 - 0.11 12.1 0.4 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Fungal fruit body lectin Malic_M PF03949.10 KFP06047.1 - 3e-94 315.3 0.5 3.8e-94 314.9 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFP06047.1 - 2.5e-71 239.0 0.0 3.9e-71 238.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Peptidase_S28 PF05577.7 KFP06048.1 - 1.7e-99 333.3 0.0 2e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KFP06048.1 - 7.6e-07 29.2 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP06048.1 - 0.00011 21.8 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFP06048.1 - 0.00014 21.6 0.1 0.00031 20.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFP06048.1 - 0.00064 18.9 0.1 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.6 KFP06048.1 - 0.0016 16.9 0.0 0.0029 16.1 0.0 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 DUF2920 PF11144.3 KFP06048.1 - 0.023 13.7 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Rep_fac-A_C PF08646.5 KFP06049.1 - 1.3e-10 41.1 0.1 2.5e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain Ras PF00071.17 KFP06051.1 - 1.3e-49 167.6 0.0 1.6e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06051.1 - 2.6e-17 63.4 0.0 4.3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06051.1 - 9.1e-14 51.0 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP06051.1 - 2.8e-07 29.9 0.0 7.6e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP06051.1 - 0.00011 21.6 0.0 0.0048 16.3 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA PF00004.24 KFP06051.1 - 0.00026 21.1 0.0 0.0015 18.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KFP06051.1 - 0.00031 20.3 0.1 0.37 10.3 0.1 2.3 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KFP06051.1 - 0.00044 20.1 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.9 KFP06051.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFP06051.1 - 0.0015 18.6 0.1 0.0037 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KFP06051.1 - 0.0024 17.3 0.1 0.024 14.1 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KFP06051.1 - 0.0032 16.7 0.2 2.3 7.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.1 KFP06051.1 - 0.016 15.1 0.3 0.029 14.3 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 KFP06051.1 - 0.018 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.14 KFP06051.1 - 0.028 13.8 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KFP06051.1 - 0.031 13.9 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 KFP06051.1 - 0.037 13.9 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFP06051.1 - 0.095 11.8 0.0 0.25 10.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 CTD_bind PF04818.8 KFP06052.1 - 7.8e-06 26.0 0.1 2.5e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. SHOCT PF09851.4 KFP06052.1 - 0.0033 16.8 1.0 0.01 15.2 0.1 2.2 2 0 0 2 2 2 1 Short C-terminal domain Ank_2 PF12796.2 KFP06053.1 - 1.5e-49 166.2 9.0 3.6e-15 56.0 0.3 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP06053.1 - 6e-41 138.1 13.0 2.2e-10 40.7 0.1 7.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 KFP06053.1 - 1.4e-40 135.0 17.9 1.4e-07 30.9 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KFP06053.1 - 1.7e-33 113.8 20.7 1.2e-09 38.0 0.0 8.3 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP06053.1 - 1.6e-24 83.5 11.0 0.00019 21.3 0.0 8.5 9 0 0 9 9 9 5 Ankyrin repeat Vps51 PF08700.6 KFP06053.1 - 0.055 13.3 3.2 0.16 11.8 2.2 1.8 1 0 0 1 1 1 0 Vps51/Vps67 CRAM_rpt PF07016.6 KFP06053.1 - 2.6 7.4 7.0 9.7 5.6 0.3 2.6 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor IncA PF04156.9 KFP06053.1 - 8.5 5.9 14.0 14 5.2 9.7 1.4 1 0 0 1 1 1 0 IncA protein DUF1640 PF07798.6 KFP06054.1 - 8.1e-69 231.1 11.9 9.5e-69 230.9 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Vac_Fusion PF02346.11 KFP06054.1 - 0.013 14.9 3.3 0.052 12.9 0.1 3.1 2 2 1 3 3 3 0 Chordopoxvirus fusion protein DUF3509 PF12021.3 KFP06054.1 - 0.041 13.6 2.9 0.2 11.4 2.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3509) MHC_I_2 PF14586.1 KFP06054.1 - 0.041 13.4 0.2 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 HALZ PF02183.13 KFP06054.1 - 0.044 13.5 1.5 0.073 12.8 0.3 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 KFP06054.1 - 2.9 8.2 11.3 1.5 9.2 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CemA PF03040.9 KFP06054.1 - 3.6 7.1 9.7 9.5 5.7 0.0 2.9 1 1 2 3 3 3 0 CemA family FlaC_arch PF05377.6 KFP06054.1 - 3.8 7.4 6.6 3.1 7.7 1.2 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2175 PF09943.4 KFP06054.1 - 6.6 6.8 9.2 2.6 8.1 2.1 2.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Guanylate_kin PF00625.16 KFP06055.1 - 1.3e-64 216.9 0.1 2.3e-64 216.2 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.23 KFP06055.1 - 2.8e-09 36.1 0.2 7.3e-09 34.8 0.2 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP06055.1 - 4.4e-09 35.6 0.0 9.4e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFP06055.1 - 8.8e-05 22.0 0.0 0.00021 20.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.19 KFP06055.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Ribosomal_L29 PF00831.18 KFP06055.1 - 0.15 11.7 1.7 13 5.5 0.4 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein RHD PF00554.17 KFP06056.1 - 1.3e-76 256.0 0.0 2.1e-76 255.3 0.0 1.4 1 0 0 1 1 1 1 Rel homology domain (RHD) TPD PF14811.1 KFP06057.1 - 0.0071 15.8 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif TFIID_20kDa PF03847.8 KFP06057.1 - 0.27 11.5 3.4 69 3.8 0.0 4.0 4 0 0 4 4 4 0 Transcription initiation factor TFIID subunit A Peroxin-13_N PF04088.8 KFP06058.1 - 3.3e-46 157.1 0.1 5.7e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 KFP06058.1 - 5.2e-10 38.7 0.1 1.3e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFP06058.1 - 1.2e-06 27.7 0.0 2.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP06058.1 - 3.8e-06 26.2 0.0 7.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3342 PF11822.3 KFP06059.1 - 8.9e-107 356.8 11.4 1.2e-106 356.4 7.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BTB PF00651.26 KFP06059.1 - 0.087 12.8 0.2 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 BTB/POZ domain Cadherin PF00028.12 KFP06060.1 - 2.5e-25 88.5 1.1 3.3e-16 59.2 0.1 2.6 2 1 0 2 2 2 2 Cadherin domain Cadherin_pro PF08758.6 KFP06060.1 - 0.0076 16.0 0.0 0.62 9.8 0.0 2.2 2 0 0 2 2 2 2 Cadherin prodomain like Cadherin PF00028.12 KFP06062.1 - 4.1e-07 30.1 0.6 1.4e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 Cadherin domain VIT1 PF01988.14 KFP06062.1 - 0.041 13.3 0.7 0.26 10.7 0.5 2.0 1 1 0 1 1 1 0 VIT family AHSA1 PF08327.6 KFP06063.1 - 3.7e-16 59.3 0.0 7.1e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.6 KFP06063.1 - 1.1e-13 51.1 1.0 2.1e-13 50.2 0.3 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal CRM1_C PF08767.6 KFP06064.1 - 1.3e-137 458.0 8.4 1.7e-137 457.6 0.9 2.7 2 0 0 2 2 2 2 CRM1 C terminal Xpo1 PF08389.7 KFP06064.1 - 9.6e-39 132.6 3.6 9.6e-39 132.6 2.5 5.4 7 1 0 7 7 7 1 Exportin 1-like protein IBN_N PF03810.14 KFP06064.1 - 5e-12 45.5 0.2 2.6e-11 43.2 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain UPF0564 PF10595.4 KFP06065.1 - 3.7e-79 266.2 38.4 7.1e-79 265.2 26.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 Cpn60_TCP1 PF00118.19 KFP06066.1 - 1.1e-145 485.9 14.3 1.3e-145 485.7 9.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KFP06066.1 - 0.0098 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 Phage Tail Protein X LRR_8 PF13855.1 KFP06067.1 - 3.5e-35 119.5 41.2 3.4e-11 42.7 1.0 5.4 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFP06067.1 - 5.1e-17 61.0 26.2 2.3e-05 23.9 1.9 7.1 4 2 3 7 7 7 6 Leucine Rich repeats (2 copies) fn3 PF00041.16 KFP06067.1 - 1e-10 41.5 0.1 3e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain LRR_1 PF00560.28 KFP06067.1 - 6.9e-05 22.3 30.8 1.5 9.1 0.2 9.7 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.1 KFP06067.1 - 0.00023 20.9 22.4 4.7 7.5 0.1 7.4 7 1 1 8 8 8 4 Leucine Rich repeat LRR_7 PF13504.1 KFP06067.1 - 3.3 8.2 28.4 26 5.6 0.0 8.6 10 0 0 10 10 10 0 Leucine rich repeat FERM_M PF00373.13 KFP06068.1 - 5.2e-42 142.9 0.3 1.3e-41 141.7 0.2 1.7 1 0 0 1 1 1 1 FERM central domain PH PF00169.24 KFP06068.1 - 3.4e-08 33.6 0.0 1.2e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 PH domain FERM_N PF09379.5 KFP06068.1 - 2.5e-05 24.2 0.0 0.00018 21.4 0.0 2.5 2 1 0 2 2 2 1 FERM N-terminal domain PH_8 PF15409.1 KFP06068.1 - 0.049 13.7 0.0 0.049 13.7 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain TGFb_propeptide PF00688.13 KFP06069.1 - 3.6e-46 157.3 2.0 5e-46 156.9 1.4 1.2 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFP06069.1 - 1.1e-41 141.3 0.8 2e-41 140.5 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain DUF908 PF06012.7 KFP06069.1 - 0.011 15.0 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FMN_dh PF01070.13 KFP06070.1 - 2.3e-135 451.0 0.0 2.7e-135 450.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFP06070.1 - 7.3e-06 25.0 0.2 1.5e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KFP06070.1 - 1.7e-05 24.0 0.5 0.14 11.2 0.0 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KFP06070.1 - 2.2e-05 23.5 0.1 3.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KFP06070.1 - 0.00055 19.2 0.5 0.0073 15.5 0.1 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein Dus PF01207.12 KFP06070.1 - 0.0037 16.1 0.1 1.4 7.6 0.0 2.4 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 KFP06070.1 - 0.0038 16.2 0.2 0.013 14.4 0.0 1.9 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase CdhD PF03599.11 KFP06070.1 - 0.0055 15.2 0.0 0.0084 14.6 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit PA PF02225.17 KFP06070.1 - 0.021 14.5 0.3 4.8 6.9 0.1 2.7 2 1 1 3 3 3 0 PA domain NMO PF03060.10 KFP06070.1 - 0.022 13.9 2.1 0.054 12.6 1.5 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.12 KFP06070.1 - 0.044 12.9 0.5 0.23 10.5 0.0 2.3 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI Thioredoxin PF00085.15 KFP06071.1 - 3.9e-19 68.2 0.0 4.9e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFP06071.1 - 0.0072 16.5 0.1 0.15 12.2 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFP06071.1 - 0.016 15.3 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KFP06071.1 - 0.032 13.7 0.1 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 KFP06071.1 - 0.086 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain DUF953 PF06110.6 KFP06071.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 KFP06071.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like PI-PLC-X PF00388.14 KFP06072.1 - 3.1e-65 218.0 0.0 3.1e-65 218.0 0.0 2.6 3 1 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PLC-beta_C PF08703.5 KFP06072.1 - 2.3e-57 193.7 47.2 2.3e-57 193.7 32.7 2.7 3 0 0 3 3 3 1 PLC-beta C terminal PI-PLC-Y PF00387.14 KFP06072.1 - 8.8e-45 151.4 2.0 8.8e-45 151.4 1.4 4.0 3 1 1 4 4 4 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFP06072.1 - 6.7e-24 83.7 0.1 6.7e-24 83.7 0.0 3.5 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like Lamp PF01299.12 KFP06073.1 - 3.2e-27 95.4 0.1 4.1e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Chordopox_A13L PF05961.6 KFP06073.1 - 0.088 12.7 0.1 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Pkinase PF00069.20 KFP06074.1 - 8.3e-70 234.8 0.0 1.2e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06074.1 - 4.8e-45 153.6 0.0 6.8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFP06074.1 - 1.1e-13 51.3 0.1 3.3e-13 49.8 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KFP06074.1 - 3.3e-08 32.8 0.0 6.3e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFP06074.1 - 0.021 14.5 0.2 2.7 7.6 0.0 3.0 1 1 2 3 3 3 0 Phosphotransferase enzyme family Med15 PF09606.5 KFP06074.1 - 2.1 6.4 10.8 3.9 5.5 7.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal adh_short PF00106.20 KFP06075.1 - 3.1e-10 40.2 0.0 6.3e-10 39.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase DUF1776 PF08643.5 KFP06075.1 - 2.2e-05 23.7 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 KFP06075.1 - 0.00024 20.9 0.0 0.00038 20.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HMG_box PF00505.14 KFP06075.1 - 0.0021 18.3 2.1 0.0034 17.6 0.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box Ank_2 PF12796.2 KFP06076.1 - 1.1e-67 224.4 4.2 1.5e-20 73.3 0.0 5.8 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFP06076.1 - 2.8e-61 200.4 8.9 6.2e-10 38.3 0.0 10.2 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KFP06076.1 - 3e-49 164.5 7.4 2e-15 56.8 0.0 7.9 4 1 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP06076.1 - 1.7e-45 148.4 7.9 8.7e-08 31.6 0.0 10.2 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 KFP06076.1 - 2.5e-43 145.1 9.8 1.2e-08 34.9 0.0 9.6 4 3 6 10 10 10 8 Ankyrin repeats (many copies) SNAP-25 PF00835.14 KFP06077.1 - 3.9e-18 65.9 0.1 8.5e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 SNAP-25 family SNARE PF05739.14 KFP06077.1 - 8.3e-18 63.8 14.9 4.9e-12 45.3 4.2 2.2 2 0 0 2 2 2 2 SNARE domain V-SNARE_C PF12352.3 KFP06077.1 - 0.057 13.4 3.1 0.3 11.1 0.0 2.7 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF4200 PF13863.1 KFP06077.1 - 0.26 11.2 2.4 1.3 9.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Cpn60_TCP1 PF00118.19 KFP06078.1 - 6e-84 282.3 0.0 7.7e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EGF PF00008.22 KFP06079.1 - 2.4e-78 257.4 280.6 1.4e-09 37.7 5.6 19.5 19 1 0 19 19 19 14 EGF-like domain MNNL PF07657.8 KFP06079.1 - 2.8e-30 104.0 2.6 2.8e-30 104.0 1.8 6.3 6 0 0 6 6 6 1 N terminus of Notch ligand DSL PF01414.14 KFP06079.1 - 1.8e-27 95.0 8.6 1.8e-27 95.0 5.9 15.6 14 3 3 17 17 17 2 Delta serrate ligand EGF_2 PF07974.8 KFP06079.1 - 2.8e-25 88.1 324.2 0.00034 20.7 7.4 19.8 19 0 0 19 19 19 15 EGF-like domain hEGF PF12661.2 KFP06079.1 - 1.8e-19 68.4 189.8 0.012 15.5 2.5 19.6 19 0 0 19 19 19 14 Human growth factor-like EGF EGF_CA PF07645.10 KFP06079.1 - 6.6e-07 29.2 25.0 4.5e-05 23.3 6.0 19.3 10 5 9 20 20 20 11 Calcium-binding EGF domain Peptidase_S49_N PF08496.5 KFP06079.1 - 0.48 10.2 0.3 0.75 9.5 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PHR PF08005.7 KFP06080.1 - 5.2e-45 153.3 0.6 8.8e-45 152.5 0.4 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 KFP06080.1 - 5.3e-24 84.3 0.0 4.1e-23 81.4 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFP06080.1 - 3.2e-07 30.1 3.3 4.1e-07 29.7 0.8 2.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch SR-25 PF10500.4 KFP06080.1 - 0.011 15.2 0.2 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_membrane PF00664.18 KFP06082.1 - 1.5e-96 323.0 39.0 8.9e-49 166.3 11.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region CFTR_R PF14396.1 KFP06082.1 - 7.8e-94 313.0 1.2 7.8e-94 313.0 0.8 1.8 2 0 0 2 2 2 1 Cystic fibrosis TM conductance regulator (CFTR), regulator domain ABC_tran PF00005.22 KFP06082.1 - 5.7e-35 120.5 0.0 6.1e-22 78.3 0.0 3.6 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFP06082.1 - 5.2e-06 25.8 0.0 0.0029 16.8 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFP06082.1 - 3.1e-05 24.0 2.3 0.0089 16.0 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KFP06082.1 - 4.1e-05 22.7 0.3 0.00038 19.6 0.0 2.7 4 0 0 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 KFP06082.1 - 0.025 13.7 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFP06082.1 - 1.3 9.2 13.0 3.9 7.7 4.1 3.7 3 1 0 3 3 3 0 AAA domain Ank_2 PF12796.2 KFP06083.1 - 1.6e-37 127.6 5.3 5.6e-21 74.6 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP06083.1 - 2.5e-34 115.3 1.0 2.3e-09 36.5 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KFP06083.1 - 5.8e-27 93.5 4.9 2.5e-11 43.7 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP06083.1 - 4.7e-26 90.2 3.5 2.2e-12 46.7 0.3 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP06083.1 - 5.4e-24 81.8 0.6 1.4e-06 28.0 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat SAM_1 PF00536.25 KFP06083.1 - 1.6e-09 37.7 0.2 3.3e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP06083.1 - 1.9e-08 34.0 0.2 4.7e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) wnt PF00110.14 KFP06084.1 - 9.4e-121 402.7 27.7 1.1e-120 402.5 19.2 1.0 1 0 0 1 1 1 1 wnt family ST7 PF04184.7 KFP06085.1 - 4.7e-276 916.2 3.3 6.5e-276 915.7 2.3 1.2 1 0 0 1 1 1 1 ST7 protein TPR_6 PF13174.1 KFP06085.1 - 0.00013 22.1 0.5 0.00058 20.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.15 KFP06085.1 - 0.041 13.4 0.1 0.095 12.3 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_2 PF07719.12 KFP06085.1 - 0.12 12.2 5.7 2.7 8.1 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFP06085.1 - 0.13 11.9 2.8 20 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFP06085.1 - 3.2 8.1 7.3 1.3 9.3 0.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFP06085.1 - 9.2 7.0 12.1 0.75 10.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat F-actin_cap_A PF01267.12 KFP06086.1 - 5.4e-103 343.7 3.4 6e-103 343.6 2.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.12 KFP06086.1 - 0.044 12.9 1.3 0.088 11.9 0.9 1.5 1 1 0 1 1 1 0 F-actin capping protein, beta subunit Sema PF01403.14 KFP06087.1 - 2.5e-105 352.5 5.1 3.9e-105 351.8 3.5 1.2 1 0 0 1 1 1 1 Sema domain Pkinase_Tyr PF07714.12 KFP06087.1 - 3e-93 311.6 0.0 4.5e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06087.1 - 6.2e-43 146.8 0.0 1.1e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 KFP06087.1 - 4.6e-34 116.2 7.9 3.5e-15 55.7 0.1 4.9 4 0 0 4 4 4 4 IPT/TIG domain PSI PF01437.20 KFP06087.1 - 6.6e-08 32.5 16.2 3e-07 30.4 11.3 2.2 1 0 0 1 1 1 1 Plexin repeat Kinase-like PF14531.1 KFP06087.1 - 2.3e-05 23.4 0.0 5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Caveolin PF01146.12 KFP06088.1 - 5.6e-56 188.2 4.4 6.1e-56 188.1 3.1 1.0 1 0 0 1 1 1 1 Caveolin Caveolin PF01146.12 KFP06089.1 - 4.4e-53 178.8 6.2 4.8e-53 178.7 4.3 1.0 1 0 0 1 1 1 1 Caveolin Flu_C_NS2 PF03555.9 KFP06090.1 - 0.037 13.9 0.4 0.051 13.5 0.3 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) DUF4498 PF14926.1 KFP06091.1 - 0.051 12.7 0.1 0.052 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) Pkinase_Tyr PF07714.12 KFP06092.1 - 2.9e-50 170.7 0.0 5.6e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06092.1 - 4.5e-43 147.2 0.0 8.2e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain KSR1-SAM PF13543.1 KFP06092.1 - 5.9e-22 77.8 0.2 9.9e-22 77.1 0.2 1.4 1 0 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 Kinase-like PF14531.1 KFP06092.1 - 5.3e-05 22.3 0.0 8.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like C1_1 PF00130.17 KFP06092.1 - 0.00038 20.1 12.4 0.00073 19.2 8.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.17 KFP06092.1 - 0.003 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFP06092.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING-like PF08746.6 KFP06092.1 - 0.1 12.6 7.9 0.29 11.1 5.5 1.8 1 0 0 1 1 1 0 RING-like domain TRAP_alpha PF03896.11 KFP06092.1 - 0.23 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NO_synthase PF02898.10 KFP06093.1 - 3.8e-218 723.4 0.3 5.3e-218 723.0 0.2 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain FAD_binding_1 PF00667.15 KFP06093.1 - 2.8e-68 229.6 0.0 9e-68 227.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 KFP06093.1 - 1e-41 142.2 0.0 2e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFP06093.1 - 1.5e-21 77.0 0.0 4.3e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Complex1_LYR PF05347.10 KFP06094.1 - 8.9e-15 54.2 0.8 9.7e-15 54.1 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFP06094.1 - 7.4e-14 51.7 0.3 8.8e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Sigma70_r4 PF04545.11 KFP06094.1 - 0.074 12.3 1.3 8.8 5.7 0.1 2.3 2 1 0 2 2 2 0 Sigma-70, region 4 DUF982 PF06169.7 KFP06094.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF982) CitG PF01874.11 KFP06094.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.3 1 1 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Pkinase PF00069.20 KFP06095.1 - 6.5e-68 228.6 0.0 8.6e-68 228.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06095.1 - 5.1e-31 107.6 0.0 7.9e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06095.1 - 0.00015 20.8 0.0 0.00052 19.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP06095.1 - 0.029 14.0 6.5 0.15 11.7 4.5 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family YppG PF14179.1 KFP06095.1 - 0.44 11.1 5.4 8.3 7.0 3.8 2.4 2 0 0 2 2 2 0 YppG-like protein DUF2781 PF10914.3 KFP06096.1 - 4.9e-20 71.8 1.6 5.2e-20 71.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) IFT20 PF14931.1 KFP06097.1 - 5.4e-32 110.1 8.8 6e-32 110.0 6.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 HRDC PF00570.18 KFP06097.1 - 0.018 14.7 0.8 0.024 14.3 0.6 1.2 1 0 0 1 1 1 0 HRDC domain DUF3135 PF11333.3 KFP06097.1 - 0.056 13.5 1.4 0.073 13.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) OmpH PF03938.9 KFP06097.1 - 0.54 10.1 8.2 0.71 9.8 5.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YebO PF13974.1 KFP06097.1 - 3.9 7.3 6.9 2.6 7.9 3.3 1.8 1 1 1 2 2 2 0 YebO-like protein BTB_2 PF02214.17 KFP06098.1 - 2e-20 72.7 0.0 4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KFP06098.1 - 4.5e-06 26.6 0.0 9.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RUN PF02759.14 KFP06099.1 - 3.7e-38 130.3 0.0 1.7e-37 128.1 0.0 2.2 2 0 0 2 2 2 1 RUN domain RabGAP-TBC PF00566.13 KFP06099.1 - 4.5e-31 107.9 10.0 2.3e-29 102.4 4.3 2.7 3 0 0 3 3 3 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 KFP06099.1 - 3.2e-07 29.8 0.0 0.00029 20.2 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3548) HLH PF00010.21 KFP06100.1 - 4.9e-13 48.5 2.0 1.5e-12 47.0 1.4 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sipho_Gp157 PF05565.6 KFP06100.1 - 0.002 17.7 2.5 0.0036 16.8 1.8 1.4 1 0 0 1 1 1 1 Siphovirus Gp157 DDE_Tnp_IS66 PF03050.9 KFP06100.1 - 0.057 12.6 2.1 0.087 12.0 1.4 1.2 1 0 0 1 1 1 0 Transposase IS66 family DUF773 PF05600.7 KFP06100.1 - 0.83 8.3 8.3 0.081 11.6 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF773) DUF2630 PF10944.3 KFP06100.1 - 2 8.5 6.9 0.8 9.8 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) APG6 PF04111.7 KFP06100.1 - 2.1 7.2 7.6 3 6.8 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFP06100.1 - 4.7 6.7 6.9 7.3 6.1 4.8 1.3 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 KFP06101.1 - 4.9e-87 283.0 18.6 4.3e-14 51.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFP06101.1 - 1.6e-12 46.3 12.2 0.0049 15.0 0.0 6.5 2 2 5 7 7 7 5 Nucleoporin Nup120/160 LisH PF08513.6 KFP06101.1 - 9.9e-09 34.6 0.4 2.3e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 KFP06101.1 - 1.2e-05 24.3 0.5 0.77 8.4 0.0 4.4 1 1 3 4 4 4 2 Nup133 N terminal like Rav1p_C PF12234.3 KFP06101.1 - 0.012 13.7 0.1 0.05 11.7 0.0 1.8 2 0 0 2 2 2 0 RAVE protein 1 C terminal Pox_A_type_inc PF04508.7 KFP06101.1 - 0.037 13.8 0.4 0.037 13.8 0.3 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 KFP06101.1 - 0.12 12.6 1.5 0.21 11.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CLU PF13236.1 KFP06102.1 - 2.2e-91 305.1 0.0 3.8e-91 304.4 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KFP06102.1 - 2.6e-57 193.4 0.1 6.1e-57 192.2 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KFP06102.1 - 1.4e-24 86.0 4.4 3.4e-24 84.7 0.1 2.8 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KFP06102.1 - 1.2e-17 63.6 9.6 1.5e-08 34.4 0.3 3.7 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFP06102.1 - 2.1e-11 43.3 4.0 0.00073 19.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP06102.1 - 0.0074 15.9 0.7 2.9 7.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.7 KFP06102.1 - 0.012 15.4 0.0 0.042 13.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_11 PF13414.1 KFP06102.1 - 0.015 14.8 6.5 0.7 9.5 0.2 3.1 2 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.12 KFP06102.1 - 0.23 11.4 2.8 2.6 8.1 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat CCDC92 PF14916.1 KFP06103.1 - 1.7e-15 56.3 13.4 1.7e-15 56.3 9.3 2.1 1 1 1 2 2 2 1 Coiled-coil domain of unknown function Transposase_22 PF02994.9 KFP06103.1 - 0.022 13.2 8.5 0.04 12.4 5.9 1.4 1 1 0 1 1 1 0 L1 transposable element CENP-P PF13096.1 KFP06103.1 - 0.033 13.5 1.4 0.046 13.0 0.9 1.2 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P FlxA PF14282.1 KFP06103.1 - 0.047 13.6 11.8 1.4 8.8 4.6 2.1 1 1 1 2 2 2 0 FlxA-like protein bZIP_1 PF00170.16 KFP06103.1 - 0.28 11.1 13.8 0.46 10.4 3.8 3.1 2 1 0 2 2 2 0 bZIP transcription factor EIAV_Rev PF11129.3 KFP06103.1 - 0.33 10.9 5.1 0.46 10.4 1.7 1.9 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus APG6 PF04111.7 KFP06103.1 - 0.37 9.8 14.7 0.45 9.5 10.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_S49_N PF08496.5 KFP06103.1 - 0.51 10.1 4.9 0.63 9.8 3.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NYD-SP28 PF14772.1 KFP06103.1 - 0.61 10.2 14.7 1.1 9.4 0.1 3.3 1 1 2 3 3 3 0 Sperm tail DivIC PF04977.10 KFP06103.1 - 0.67 9.4 16.4 9.2 5.8 2.5 3.1 1 1 1 2 2 2 0 Septum formation initiator IncA PF04156.9 KFP06103.1 - 1 8.9 21.9 3.6 7.1 15.2 1.8 1 1 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 KFP06103.1 - 1.5 8.7 6.7 3.6 7.5 0.8 3.0 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 KFP06103.1 - 2.6 7.8 18.2 7 6.4 12.4 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Tox-ODYAM1 PF15642.1 KFP06103.1 - 3.3 6.2 9.1 3.8 6.0 6.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Spc7 PF08317.6 KFP06103.1 - 4.5 5.8 15.0 5.5 5.5 10.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TPD52 PF04201.10 KFP06103.1 - 4.9 6.8 15.8 1.4 8.6 5.0 2.4 1 1 1 2 2 2 0 Tumour protein D52 family DUF724 PF05266.9 KFP06103.1 - 5.6 6.5 16.1 1.9 8.0 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TBPIP PF07106.8 KFP06103.1 - 6.1 6.3 14.4 9.5 5.7 3.5 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rap_GAP PF02145.10 KFP06104.1 - 1e-56 191.3 0.0 2.1e-56 190.3 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP WSC PF01822.14 KFP06105.1 - 3.8e-31 106.8 18.1 6.4e-20 70.8 7.0 2.3 2 0 0 2 2 2 2 WSC domain Sulfotransfer_1 PF00685.22 KFP06105.1 - 3.2e-08 33.1 0.2 6e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase domain DUF2859 PF11072.3 KFP06105.1 - 0.025 14.0 0.2 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) CarbpepA_inh PF02977.10 KFP06106.1 - 0.008 15.7 1.8 0.008 15.7 1.2 2.9 3 0 0 3 3 3 1 Carboxypeptidase A inhibitor DZR PF12773.2 KFP06106.1 - 0.11 12.3 12.0 0.08 12.7 1.9 3.6 3 1 0 3 3 3 0 Double zinc ribbon zf-C2H2_4 PF13894.1 KFP06106.1 - 0.13 12.6 5.6 2.3 8.7 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP06106.1 - 5.6 7.5 16.2 1.2 9.5 0.6 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type Na_sulph_symp PF00939.14 KFP06107.1 - 5.3e-116 388.2 23.7 6.2e-116 388.0 16.5 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFP06107.1 - 2.5e-17 62.5 41.1 2.2e-06 26.4 8.1 3.1 3 0 0 3 3 3 3 Citrate transporter UPF0121 PF03661.8 KFP06107.1 - 0.98 8.5 6.0 0.57 9.3 2.6 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) Med31 PF05669.7 KFP06108.1 - 5.2e-43 144.9 9.2 6.9e-43 144.5 6.4 1.1 1 0 0 1 1 1 1 SOH1 DUF953 PF06110.6 KFP06109.1 - 1.4e-45 153.5 0.0 1.5e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.1 KFP06109.1 - 0.02 15.0 0.2 0.036 14.2 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KFP06109.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin DDHD PF02862.12 KFP06110.1 - 9.8e-47 159.6 0.0 2.3e-46 158.4 0.0 1.7 1 0 0 1 1 1 1 DDHD domain LNS2 PF08235.8 KFP06110.1 - 1.2e-37 128.9 0.1 2e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Acid_phosphat_B PF03767.9 KFP06110.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF1466 PF07326.6 KFP06111.1 - 2.2e-10 40.2 0.6 2.5e-10 40.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1466) Ldh_1_N PF00056.18 KFP06111.1 - 0.052 13.3 0.1 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F-box-like PF12937.2 KFP06112.1 - 8.8e-09 34.9 2.1 8.8e-09 34.9 1.4 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFP06112.1 - 1.6e-06 27.5 0.2 1.6e-06 27.5 0.1 2.7 3 0 0 3 3 3 1 F-box domain Tektin PF03148.9 KFP06113.1 - 4.8e-139 463.1 32.1 5.4e-139 463.0 22.2 1.0 1 0 0 1 1 1 1 Tektin family HN PF00423.14 KFP06113.1 - 1.7 6.8 7.7 0.62 8.2 1.6 2.4 1 1 1 2 2 2 0 Haemagglutinin-neuraminidase CH PF00307.26 KFP06114.1 - 1.7e-17 63.4 0.3 3.3e-17 62.4 0.1 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP06114.1 - 2.2e-06 27.2 0.1 4.5e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Ank_2 PF12796.2 KFP06115.1 - 2.7e-20 72.4 0.0 4.5e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP06115.1 - 1.8e-19 68.4 0.1 1.4e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KFP06115.1 - 2.6e-18 65.6 0.0 2.4e-10 40.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP06115.1 - 5.4e-18 64.9 0.1 5.6e-12 45.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP06115.1 - 8e-14 50.3 0.1 1.4e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat FAM180 PF15173.1 KFP06117.1 - 1.2e-61 206.4 0.4 1.3e-61 206.3 0.3 1.0 1 0 0 1 1 1 1 FAM180 family Flag1_repress PF03614.8 KFP06117.1 - 0.068 12.7 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Na_sulph_symp PF00939.14 KFP06118.1 - 6e-98 328.7 10.3 9.9e-98 328.0 7.2 1.3 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFP06118.1 - 1.4e-14 53.5 27.2 5.8e-07 28.4 7.0 3.1 2 1 1 3 3 3 3 Citrate transporter ArsB PF02040.10 KFP06118.1 - 3.8e-06 26.1 11.4 0.0047 15.9 2.6 2.6 2 0 0 2 2 2 2 Arsenical pump membrane protein Lipase_GDSL_2 PF13472.1 KFP06119.1 - 0.00013 22.2 0.0 0.00025 21.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family C2 PF00168.25 KFP06121.1 - 2.5e-56 187.4 0.2 7.1e-29 99.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 KFP06121.1 - 0.002 17.6 0.0 0.25 10.8 0.0 2.6 2 0 0 2 2 2 2 CEP76 C2 domain PI3K_C2 PF00792.19 KFP06121.1 - 0.003 17.3 0.0 2.6 7.7 0.0 3.4 3 1 0 3 3 3 2 Phosphoinositide 3-kinase C2 ETS_PEA3_N PF04621.8 KFP06121.1 - 0.0066 15.7 2.3 0.01 15.1 1.6 1.2 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain MOZART1 PF12554.3 KFP06122.1 - 3.4e-23 80.8 0.3 3.9e-23 80.6 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated BORA_N PF15280.1 KFP06123.1 - 6.2e-65 218.5 5.3 6.2e-65 218.5 3.6 1.9 2 0 0 2 2 2 1 Protein aurora borealis N-terminus IRS PF02174.12 KFP06124.1 - 2.7e-27 94.3 0.1 6.5e-27 93.0 0.1 1.6 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Cpn60_TCP1 PF00118.19 KFP06125.1 - 4.6e-138 460.8 7.7 5.4e-138 460.6 5.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Asp PF00026.18 KFP06126.1 - 3.6e-114 381.2 0.0 4.1e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFP06126.1 - 2.4e-08 34.1 0.0 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal A1_Propeptide PF07966.7 KFP06126.1 - 8.9e-06 25.3 0.7 1.6e-05 24.4 0.5 1.4 1 0 0 1 1 1 1 A1 Propeptide TAXi_C PF14541.1 KFP06126.1 - 8.1e-05 22.2 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Bestrophin PF01062.16 KFP06127.1 - 9.3e-94 313.6 5.3 1.2e-93 313.3 3.7 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sec2p PF06428.6 KFP06128.1 - 1e-25 89.4 8.7 2.1e-25 88.5 5.9 1.6 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.14 KFP06128.1 - 0.00091 17.0 10.6 0.0013 16.6 7.4 1.1 1 0 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 KFP06128.1 - 0.0092 14.5 4.1 0.012 14.1 2.9 1.1 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 KFP06128.1 - 0.099 9.9 7.5 0.14 9.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 KFP06128.1 - 0.51 9.3 9.1 0.76 8.7 6.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 KFP06128.1 - 0.9 9.4 14.8 2.2 8.2 10.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 KFP06128.1 - 0.95 9.5 10.1 2.1 8.3 7.0 1.5 1 0 0 1 1 1 0 DivIVA protein Tropomyosin_1 PF12718.2 KFP06128.1 - 1.3 8.8 15.9 3.9 7.3 11.0 1.7 1 1 0 1 1 1 0 Tropomyosin like IncA PF04156.9 KFP06128.1 - 6.7 6.2 13.3 19 4.7 9.2 1.6 1 1 0 1 1 1 0 IncA protein NOT2_3_5 PF04153.13 KFP06129.1 - 5.4e-34 116.9 0.2 1e-33 116.0 0.1 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CaKB PF03185.10 KFP06130.1 - 2.9e-55 186.7 0.2 3.3e-55 186.6 0.1 1.0 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit fn3 PF00041.16 KFP06131.1 - 4.1e-163 529.9 44.7 2.2e-12 46.9 0.5 18.6 19 0 0 19 19 19 16 Fibronectin type III domain Y_phosphatase PF00102.22 KFP06131.1 - 1e-80 270.4 0.2 2e-80 269.5 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Cna_B PF05738.8 KFP06131.1 - 0.00068 19.3 8.5 1.2 8.9 0.2 7.4 10 0 0 10 10 10 1 Cna protein B-type domain DSPc PF00782.15 KFP06131.1 - 0.003 17.1 0.0 0.0075 15.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Interfer-bind PF09294.5 KFP06131.1 - 0.003 17.5 12.9 2.5 8.1 0.0 7.8 9 0 0 9 9 9 2 Interferon-alpha/beta receptor, fibronectin type III Y_phosphatase3 PF13350.1 KFP06131.1 - 0.0035 17.6 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP06131.1 - 0.0044 17.0 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate UPF0052 PF01933.13 KFP06131.1 - 0.055 12.7 0.1 0.14 11.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 SusE PF14292.1 KFP06131.1 - 0.24 11.2 22.5 10 5.9 0.0 8.8 12 0 0 12 12 12 0 SusE outer membrane protein Y_phosphatase PF00102.22 KFP06132.1 - 2.3e-77 259.4 0.1 4.3e-77 258.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP06132.1 - 0.00023 20.7 0.0 0.00053 19.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP06132.1 - 0.002 18.3 0.1 0.005 17.1 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family LRR_8 PF13855.1 KFP06133.1 - 1.1e-85 281.2 61.3 2.8e-15 55.8 2.3 8.6 2 2 8 10 10 10 9 Leucine rich repeat LRR_4 PF12799.2 KFP06133.1 - 7.1e-48 159.5 35.7 4e-08 32.7 0.0 9.9 6 3 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP06133.1 - 2.7e-33 114.4 0.0 7.9e-12 45.0 0.0 4.6 2 1 3 5 5 5 4 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP06133.1 - 6.7e-31 101.5 44.2 0.031 14.2 0.3 17.5 17 1 1 18 18 18 9 Leucine Rich Repeat LRR_7 PF13504.1 KFP06133.1 - 5.9e-19 64.8 36.4 0.44 10.9 0.3 15.6 16 0 0 16 16 16 5 Leucine rich repeat 7tm_1 PF00001.16 KFP06133.1 - 1.3e-15 57.2 15.1 1.9e-15 56.7 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_6 PF13516.1 KFP06133.1 - 1.4e-10 40.1 41.2 0.29 11.3 0.2 14.5 15 1 1 16 16 16 3 Leucine Rich repeat LRR_9 PF14580.1 KFP06133.1 - 2.7e-09 36.8 6.2 0.31 10.5 0.1 5.0 1 1 4 5 5 5 4 Leucine-rich repeat 7TM_GPCR_Srx PF10328.4 KFP06133.1 - 4.9 6.1 17.4 16 4.4 12.1 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx zf-C3H1 PF10650.4 KFP06134.1 - 1.3e-09 37.2 7.4 3e-09 36.1 5.2 1.7 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_14 PF13428.1 KFP06134.1 - 1.8e-07 31.1 9.1 0.19 12.4 0.0 6.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP06134.1 - 2e-07 31.2 7.6 0.11 12.7 0.1 6.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP06134.1 - 1.5e-06 27.9 4.7 0.024 14.8 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFP06134.1 - 5.4e-05 22.7 15.6 0.00097 18.7 0.3 5.1 5 2 1 6 6 6 3 TPR repeat TPR_12 PF13424.1 KFP06134.1 - 0.002 18.0 3.8 0.014 15.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFP06134.1 - 0.014 16.0 2.8 2.3 8.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF92 PF01940.11 KFP06136.1 - 1.7e-72 243.2 3.8 2.5e-72 242.6 2.6 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF975 PF06161.6 KFP06136.1 - 0.79 9.4 10.0 6.9 6.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF975) Sigma_reg_N PF13800.1 KFP06136.1 - 0.85 9.6 4.1 6.1 6.9 0.5 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Imm_superinfect PF14373.1 KFP06136.1 - 1.3 8.7 7.9 0.085 12.5 0.7 2.6 3 0 0 3 3 3 0 Superinfection immunity protein Ras PF00071.17 KFP06137.1 - 1.5e-43 147.9 0.1 1.8e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06137.1 - 2.9e-12 47.1 0.0 5.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06137.1 - 7.9e-10 38.2 0.1 9.7e-10 37.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP06137.1 - 2e-05 24.1 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RHH_1 PF01402.16 KFP06137.1 - 0.073 12.9 0.2 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PduV-EutP PF10662.4 KFP06137.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3548 PF12068.3 KFP06138.1 - 1.2e-87 292.6 1.1 1.2e-87 292.6 0.8 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3548) RabGAP-TBC PF00566.13 KFP06138.1 - 1.5e-11 44.1 1.3 2.5e-11 43.4 0.9 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 7tm_1 PF00001.16 KFP06139.1 - 2.4e-19 69.4 7.8 7.9e-17 61.2 0.4 2.3 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DCX PF03607.12 KFP06140.1 - 5.5e-39 131.5 0.0 3.2e-22 77.8 0.0 2.6 2 0 0 2 2 2 2 Doublecortin FHIPEP PF00771.15 KFP06140.1 - 4 5.6 5.0 1.7 6.8 1.3 1.9 1 1 0 1 1 1 0 FHIPEP family PLAT PF01477.18 KFP06141.1 - 1.3e-15 57.7 0.0 2.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain XK-related PF09815.4 KFP06143.1 - 8.9e-106 353.6 24.4 1e-105 353.4 16.9 1.0 1 0 0 1 1 1 1 XK-related protein Acyltransferase PF01553.16 KFP06145.1 - 5.4e-08 32.3 0.0 1.6e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.8 KFP06145.1 - 5.5e-05 22.0 0.0 9.2e-05 21.2 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Pkinase_Tyr PF07714.12 KFP06147.1 - 1.1e-96 322.9 0.0 1.3e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06147.1 - 1.1e-49 168.9 0.0 1.5e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP06147.1 - 1.5e-24 85.5 0.0 3.3e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFP06147.1 - 1.3e-16 59.7 0.1 2.9e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP06147.1 - 1e-11 44.2 0.1 2.5e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP06147.1 - 2.3e-09 36.5 0.4 7e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 KFP06147.1 - 0.0079 16.3 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Kinesin PF00225.18 KFP06148.1 - 1.5e-95 319.7 0.2 2.6e-95 318.9 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF342 PF03961.8 KFP06148.1 - 0.082 11.3 1.4 0.15 10.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ribosomal_S10 PF00338.17 KFP06149.1 - 5.4e-34 115.9 0.4 6.3e-34 115.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pkinase PF00069.20 KFP06150.1 - 1.4e-56 191.5 0.0 1.7e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06150.1 - 3.7e-42 144.1 0.0 4.4e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06150.1 - 0.00087 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-H2C2_2 PF13465.1 KFP06151.1 - 3.1e-28 96.6 57.8 2.6e-05 24.3 0.7 8.5 8 0 0 8 8 8 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFP06151.1 - 3.6e-23 80.4 64.6 0.00018 21.6 1.0 7.5 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP06151.1 - 2.3e-20 71.3 54.2 0.00052 20.1 1.7 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP06151.1 - 2e-07 30.9 46.2 0.04 14.0 1.0 7.2 7 1 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP06151.1 - 9.8e-06 25.2 31.9 0.0015 18.3 0.1 6.7 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.2 KFP06151.1 - 0.0002 21.4 28.0 0.59 10.4 0.3 5.9 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFP06151.1 - 0.038 14.1 40.5 0.79 9.8 1.1 5.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFP06151.1 - 3.1 8.0 37.1 0.34 11.0 0.3 5.2 2 1 4 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 KFP06151.1 - 4.8 6.7 23.7 0.3 10.5 1.3 5.4 4 2 2 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1903 PF08991.5 KFP06152.1 - 0.00021 21.3 0.5 0.00024 21.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KFP06152.1 - 0.071 13.0 5.3 0.11 12.4 3.6 1.3 1 0 0 1 1 1 0 CHCH domain Trypsin PF00089.21 KFP06153.1 - 1.7e-60 204.3 0.0 1.8e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFP06153.1 - 0.00032 20.6 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.6 KFP06153.1 - 0.00035 19.9 0.1 0.0017 17.7 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1986) Med26 PF08711.6 KFP06154.1 - 1.4e-17 62.9 0.0 5.2e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Sulfotransfer_2 PF03567.9 KFP06155.1 - 1.8e-48 165.4 0.5 2.5e-48 164.9 0.3 1.2 1 0 0 1 1 1 1 Sulfotransferase family Spore_III_AB PF09548.5 KFP06155.1 - 0.017 14.8 0.1 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF3552 PF12072.3 KFP06155.1 - 0.72 9.0 4.7 1.3 8.2 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PH PF00169.24 KFP06156.1 - 7.3e-09 35.7 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 PH domain YppG PF14179.1 KFP06156.1 - 0.034 14.7 2.4 0.05 14.2 1.6 1.2 1 0 0 1 1 1 0 YppG-like protein PH_11 PF15413.1 KFP06156.1 - 0.12 12.6 0.5 0.17 12.1 0.4 1.4 1 1 0 1 1 1 0 Pleckstrin homology domain TCRP1 PF14944.1 KFP06157.1 - 1.5e-95 318.6 46.9 1.7e-95 318.5 32.5 1.0 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 7tm_1 PF00001.16 KFP06158.1 - 2.1e-36 125.3 17.4 2.5e-36 125.1 12.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF606 PF04657.8 KFP06158.1 - 0.0014 18.7 0.2 0.0014 18.7 0.1 2.7 2 1 0 3 3 3 1 Protein of unknown function, DUF606 7tm_1 PF00001.16 KFP06159.1 - 7.4e-29 100.6 23.5 8.8e-29 100.4 16.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) C1q PF00386.16 KFP06160.1 - 5.1e-40 136.4 0.4 6.4e-40 136.0 0.3 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP06160.1 - 5e-11 41.9 23.5 1.3e-10 40.6 16.3 1.6 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.13 KFP06160.1 - 0.17 11.4 2.0 0.77 9.3 1.4 1.8 1 1 0 1 1 1 0 TNF(Tumour Necrosis Factor) family PPV_E2_N PF00508.12 KFP06160.1 - 0.22 10.6 2.2 0.17 11.0 0.4 1.6 1 1 1 2 2 2 0 E2 (early) protein, N terminal Glyco_transf_29 PF00777.13 KFP06161.1 - 5.8e-63 212.5 0.0 9.2e-63 211.8 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) MYEOV2 PF15004.1 KFP06162.1 - 1.2e-33 115.4 6.0 1.2e-33 115.3 4.2 1.0 1 0 0 1 1 1 1 Myeloma-overexpressed-like Sushi PF00084.15 KFP06163.1 - 9.8e-15 54.6 5.8 9.4e-10 38.6 0.4 2.7 3 0 0 3 3 3 2 Sushi domain (SCR repeat) Sushi PF00084.15 KFP06164.1 - 2.3e-15 56.6 1.2 2e-10 40.8 0.1 2.1 2 0 0 2 2 2 2 Sushi domain (SCR repeat) Sushi PF00084.15 KFP06165.1 - 6.7e-34 116.0 9.1 9e-13 48.3 0.6 3.1 2 1 1 3 3 3 3 Sushi domain (SCR repeat) HRM PF02793.17 KFP06165.1 - 0.0015 18.5 5.4 0.31 11.0 0.2 3.3 3 0 0 3 3 3 2 Hormone receptor domain CBM_14 PF01607.19 KFP06165.1 - 0.029 14.2 4.8 1.3 8.9 0.1 2.9 3 0 0 3 3 3 0 Chitin binding Peritrophin-A domain cEGF PF12662.2 KFP06165.1 - 4.7 6.9 7.0 5.5 6.7 0.1 3.2 3 1 0 3 3 3 0 Complement Clr-like EGF-like Sushi PF00084.15 KFP06166.1 - 3.9e-71 235.2 39.1 1.1e-10 41.6 0.0 7.1 7 0 0 7 7 7 7 Sushi domain (SCR repeat) cEGF PF12662.2 KFP06166.1 - 0.00041 19.9 17.6 0.96 9.1 0.1 6.8 7 0 0 7 7 7 3 Complement Clr-like EGF-like DUF281 PF03436.8 KFP06166.1 - 0.051 13.6 1.5 1.1 9.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF281) Sushi PF00084.15 KFP06167.1 - 2.3e-58 194.3 32.0 8.2e-12 45.3 0.2 6.2 6 0 0 6 6 6 6 Sushi domain (SCR repeat) HRM PF02793.17 KFP06167.1 - 1.5e-05 24.8 28.6 0.12 12.4 0.1 6.4 5 3 0 5 5 5 3 Hormone receptor domain Sushi PF00084.15 KFP06168.1 - 4.3e-16 58.9 2.9 5e-11 42.7 0.5 2.1 2 0 0 2 2 2 2 Sushi domain (SCR repeat) cEGF PF12662.2 KFP06168.1 - 0.18 11.4 2.3 0.21 11.2 0.4 2.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like 6PF2K PF01591.13 KFP06169.1 - 5.1e-102 339.6 1.4 7.1e-102 339.1 1.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFP06169.1 - 1e-35 123.1 0.0 1.5e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFP06169.1 - 8.2e-10 38.7 0.0 1.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFP06169.1 - 5.3e-06 25.8 0.1 1.1e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFP06169.1 - 2.6e-05 25.0 0.3 9.5e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF421 PF04239.7 KFP06169.1 - 0.0087 15.5 0.0 0.037 13.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF421) Zeta_toxin PF06414.7 KFP06169.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KFP06169.1 - 0.053 13.8 0.1 0.95 9.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KFP06169.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase His_Phos_2 PF00328.17 KFP06169.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) OTU PF02338.14 KFP06170.1 - 3.4e-11 43.7 0.0 6.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.2 KFP06170.1 - 0.036 14.1 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFP06170.1 - 0.4 10.9 2.1 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SARG PF15385.1 KFP06171.1 - 3.5e-98 330.1 42.8 4.1e-96 323.3 29.7 2.0 1 1 0 1 1 1 1 Specifically androgen-regulated gene protein V-set PF07686.12 KFP06172.1 - 7.8e-61 202.9 10.5 1.3e-15 57.2 0.3 5.3 5 0 0 5 5 5 5 Immunoglobulin V-set domain I-set PF07679.11 KFP06172.1 - 7e-10 38.6 3.0 0.28 11.0 0.1 5.8 5 2 0 5 5 5 4 Immunoglobulin I-set domain ig PF00047.20 KFP06172.1 - 1.4e-09 37.9 22.3 0.037 14.1 1.0 7.5 5 2 0 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.1 KFP06172.1 - 5.5e-09 36.0 14.7 0.0079 16.2 0.3 5.8 5 1 0 5 5 5 2 Immunoglobulin domain Pkinase PF00069.20 KFP06173.1 - 1.8e-47 161.6 0.0 2.1e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06173.1 - 4.3e-24 84.9 0.0 6.3e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFP06173.1 - 1.6e-05 24.0 0.1 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP06173.1 - 0.00089 18.2 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KFP06173.1 - 0.049 13.1 0.1 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.20 KFP06174.1 - 9e-61 205.2 0.2 1.6e-60 204.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06174.1 - 1e-21 77.1 0.1 2.3e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFP06174.1 - 3.9e-05 23.5 0.0 0.0024 17.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP06174.1 - 0.00065 19.0 3.1 0.027 13.8 0.0 2.5 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KFP06174.1 - 0.00083 18.9 0.2 0.002 17.7 0.1 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFP06174.1 - 0.0036 16.6 2.1 0.0043 16.4 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KFP06174.1 - 0.015 14.4 0.1 0.026 13.5 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RA PF00788.18 KFP06175.1 - 6.5e-17 61.8 0.2 1.6e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Pkinase PF00069.20 KFP06176.1 - 2.5e-48 164.4 0.0 3.5e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06176.1 - 2.1e-28 99.1 0.0 3.1e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06176.1 - 6.6e-05 22.0 0.0 0.0023 16.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP06176.1 - 0.023 14.4 0.0 1.9 8.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family RhoGAP PF00620.22 KFP06177.1 - 4.1e-35 120.6 1.1 6e-34 116.8 0.0 3.4 2 2 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KFP06177.1 - 2.8e-19 69.0 3.3 2.8e-19 69.0 2.3 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KFP06177.1 - 3.6e-10 39.0 0.0 6.7e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP06177.1 - 3.9e-09 35.8 0.0 8.5e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFP06177.1 - 3.9e-09 35.9 0.0 7.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.6 KFP06177.1 - 0.0072 16.2 7.1 0.021 14.7 1.8 3.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) KIP1 PF07765.7 KFP06177.1 - 0.34 10.7 4.7 3.9 7.4 0.3 3.3 3 0 0 3 3 3 0 KIP1-like protein DUF4164 PF13747.1 KFP06177.1 - 4.3 7.5 11.0 1.2 9.2 2.3 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) FAM72 PF14976.1 KFP06178.1 - 1.8e-32 112.2 0.0 1.9e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 FAM72 protein 7tm_1 PF00001.16 KFP06179.1 - 1.1e-56 191.9 3.4 1.3e-56 191.6 2.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06179.1 - 6.4e-11 41.9 0.8 9.3e-11 41.3 0.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP06179.1 - 7.7e-06 25.2 0.0 1.3e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Srg PF02118.16 KFP06179.1 - 1 8.7 9.2 0.047 13.1 1.8 2.1 2 0 0 2 2 2 0 Srg family chemoreceptor MFS_2 PF13347.1 KFP06179.1 - 1.9 6.7 11.1 0.27 9.5 0.7 2.6 1 1 0 2 2 2 0 MFS/sugar transport protein Asp PF00026.18 KFP06180.1 - 3.7e-125 417.3 0.2 4.3e-125 417.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFP06180.1 - 3.9e-10 39.9 0.3 2.7e-09 37.1 0.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFP06180.1 - 4.9e-05 23.7 0.2 0.058 13.8 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KFP06180.1 - 0.0013 18.2 0.1 0.0088 15.5 0.0 2.2 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal A1_Propeptide PF07966.7 KFP06180.1 - 0.0081 15.9 0.2 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 A1 Propeptide Ras PF00071.17 KFP06181.1 - 1e-32 112.7 0.0 1.1e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06181.1 - 4.5e-10 40.0 0.0 6.9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06181.1 - 1.9e-08 33.7 0.0 2.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP06181.1 - 0.00052 19.4 0.0 0.0011 18.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Sulfate_transp PF00916.15 KFP06182.1 - 3.8e-40 137.6 11.7 7.4e-38 130.1 7.1 3.7 3 1 0 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFP06182.1 - 1e-26 92.4 1.7 1e-26 92.4 1.2 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFP06182.1 - 4.8e-25 87.2 0.0 7.6e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain Peptidase_M20 PF01546.23 KFP06183.1 - 2.1e-27 95.8 0.0 3.9e-27 95.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFP06183.1 - 7.2e-17 61.1 0.0 1.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain MgtE PF01769.11 KFP06184.1 - 1.2e-45 155.0 19.3 5.1e-29 101.2 4.9 2.7 2 1 1 3 3 3 2 Divalent cation transporter Ras PF00071.17 KFP06185.1 - 1.5e-45 154.4 0.0 1.8e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06185.1 - 1.4e-17 64.2 0.0 2.3e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06185.1 - 5.2e-15 55.1 0.1 6.6e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP06185.1 - 3.4e-05 23.1 0.2 6.6e-05 22.1 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFP06185.1 - 0.00035 19.8 0.0 0.00053 19.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFP06185.1 - 0.0013 18.2 0.0 0.003 17.0 0.0 1.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KFP06185.1 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KFP06185.1 - 0.0044 16.9 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KFP06185.1 - 0.0083 15.6 0.1 2.4 7.6 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein DLIC PF05783.6 KFP06185.1 - 0.017 13.8 0.1 1 7.9 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.1 KFP06185.1 - 0.05 13.7 0.0 0.078 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFP06185.1 - 0.099 12.8 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2276 PF10040.4 KFP06185.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) AAA_16 PF13191.1 KFP06185.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 KFP06185.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MFS_1 PF07690.11 KFP06187.1 - 3.4e-13 49.0 32.8 2e-12 46.4 16.8 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFP06187.1 - 3.3e-11 42.2 1.0 3.3e-11 42.2 0.7 3.2 4 0 0 4 4 4 2 MFS/sugar transport protein FAM220 PF15487.1 KFP06187.1 - 0.52 9.6 3.6 0.78 9.0 2.5 1.1 1 0 0 1 1 1 0 FAM220 family Ets PF00178.17 KFP06188.1 - 8.5e-38 128.3 2.1 1.3e-37 127.8 1.4 1.2 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 KFP06188.1 - 0.079 13.1 0.3 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding MFS_1 PF07690.11 KFP06189.1 - 4.7e-13 48.5 34.0 1.4e-07 30.5 15.1 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KFP06190.1 - 2.5e-70 236.5 0.0 3e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06190.1 - 7.4e-33 113.7 0.0 9.6e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06190.1 - 6.6e-06 25.2 0.0 9.1e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP06190.1 - 0.0024 16.9 0.1 0.0057 15.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFP06190.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KFP06190.1 - 0.037 13.3 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KFP06190.1 - 0.079 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vac14_Fig4_bd PF11916.3 KFP06191.1 - 4.9e-79 263.7 8.5 7.6e-79 263.0 5.9 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding IMD PF08397.6 KFP06192.1 - 6.4e-88 293.7 1.8 8.6e-88 293.2 1.3 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain DUF3987 PF13148.1 KFP06192.1 - 0.032 12.7 1.3 0.057 11.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) IL34 PF15036.1 KFP06193.1 - 3.1e-45 153.7 2.0 3.4e-45 153.6 1.4 1.0 1 0 0 1 1 1 1 Interleukin 34 U3_assoc_6 PF08640.6 KFP06193.1 - 0.16 11.7 0.6 0.28 10.9 0.4 1.5 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 COG4 PF08318.7 KFP06194.1 - 5.2e-99 331.1 5.6 8e-99 330.5 3.9 1.3 1 0 0 1 1 1 1 COG4 transport protein 7TMR-HDED PF07697.6 KFP06194.1 - 0.013 15.2 0.7 9.3 5.9 0.0 3.3 2 1 1 3 3 3 0 7TM-HD extracellular Fucokinase PF07959.7 KFP06195.1 - 4.7e-96 321.8 0.0 6.9e-96 321.3 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.8 KFP06195.1 - 4.4e-07 30.0 0.0 1.7e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KFP06195.1 - 1.9e-05 24.6 0.2 4.9e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Glyco_transf_29 PF00777.13 KFP06196.1 - 1.1e-99 332.9 0.0 1.3e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) mono-CXXC PF15626.1 KFP06196.1 - 0.0062 16.4 3.9 0.03 14.2 0.3 2.4 2 0 0 2 2 2 1 single CXXC unit G_glu_transpept PF01019.16 KFP06196.1 - 0.019 13.4 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase MIase PF02426.11 KFP06196.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Muconolactone delta-isomerase DAO PF01266.19 KFP06197.1 - 9.2e-70 235.3 0.1 1.2e-69 234.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KFP06197.1 - 2.2e-57 193.8 0.0 3.8e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFP06197.1 - 3.3e-21 75.1 0.0 1.2e-20 73.3 0.0 2.0 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAD_binding_2 PF00890.19 KFP06197.1 - 6e-07 28.6 0.6 1.5e-06 27.3 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KFP06197.1 - 6.2e-07 29.6 0.5 3.2e-05 24.1 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KFP06197.1 - 0.0001 21.5 0.3 0.23 10.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.9 KFP06197.1 - 0.00038 19.2 1.8 0.025 13.2 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KFP06197.1 - 0.0032 17.4 0.2 0.01 15.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFP06197.1 - 0.0039 16.2 2.6 0.052 12.5 2.0 2.4 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFP06197.1 - 0.0044 16.9 0.2 0.067 13.0 0.1 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFP06197.1 - 0.005 16.9 0.0 0.031 14.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KFP06197.1 - 0.0053 15.8 0.5 0.24 10.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 KFP06197.1 - 0.0092 15.1 1.3 0.023 13.7 0.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFP06197.1 - 0.036 12.5 0.6 0.085 11.3 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KFP06197.1 - 0.039 14.3 2.1 4 7.9 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFP06197.1 - 0.088 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Cys_rich_FGFR PF00839.12 KFP06198.1 - 1.6e-199 646.0 119.0 1.8e-19 69.4 1.4 15.3 16 0 0 16 16 16 15 Cysteine rich repeat Pkinase_Tyr PF07714.12 KFP06199.1 - 2.8e-42 144.6 0.0 1e-40 139.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06199.1 - 5.8e-32 110.8 0.0 1.1e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Glu-tRNAGln PF02686.10 KFP06199.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit RNA_pol_A_CTD PF03118.10 KFP06199.1 - 0.1 12.0 0.2 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF972 PF06156.8 KFP06199.1 - 0.31 11.3 4.3 2.2 8.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) FA_hydroxylase PF04116.8 KFP06200.1 - 2.8e-13 50.2 12.6 2.8e-13 50.2 8.7 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 KFP06200.1 - 0.034 13.7 3.8 0.034 13.7 2.6 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.8 KFP06200.1 - 0.062 13.3 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Kua-UEV1_localn PF10520.4 KFP06200.1 - 6.3 6.4 11.6 0.43 10.2 2.6 2.2 1 1 1 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain WD40 PF00400.27 KFP06201.1 - 8.6e-19 66.6 17.4 1.3e-06 27.9 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KFP06201.1 - 3.4e-05 23.6 0.6 0.025 14.3 0.1 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.1 KFP06201.1 - 0.71 9.7 15.3 0.043 13.6 4.9 2.9 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 KFP06201.1 - 8.6 6.5 16.3 1.4 9.0 7.8 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 KFP06202.1 - 5.4e-14 51.7 7.4 4.1e-12 45.7 2.7 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 KFP06202.1 - 8.4e-06 25.7 12.3 2.2e-05 24.4 3.6 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP06202.1 - 7.5e-05 22.7 8.1 0.00096 19.2 3.0 2.5 1 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFP06202.1 - 0.00014 21.4 7.9 0.003 17.1 1.3 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KFP06202.1 - 0.00073 19.2 6.2 0.016 14.9 1.6 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 RINGv PF12906.2 KFP06202.1 - 0.0012 18.8 7.2 0.026 14.5 3.2 2.4 2 0 0 2 2 2 1 RING-variant domain zf-RING_5 PF14634.1 KFP06202.1 - 0.0013 18.4 6.7 0.04 13.6 1.9 2.3 2 0 0 2 2 2 2 zinc-RING finger domain FANCL_C PF11793.3 KFP06202.1 - 0.0022 17.9 6.3 0.061 13.2 2.3 2.5 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 KFP06202.1 - 0.0026 17.3 9.6 0.011 15.4 2.8 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PRP21_like_P PF12230.3 KFP06202.1 - 0.0084 15.6 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein zf-RING_UBOX PF13445.1 KFP06202.1 - 0.038 13.6 7.8 0.059 13.1 2.4 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.7 KFP06202.1 - 0.095 12.8 0.1 0.095 12.8 0.1 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KFP06202.1 - 0.13 12.6 1.6 0.18 12.2 0.1 2.1 2 0 0 2 2 1 0 C2H2-type zinc finger zf-RING_4 PF14570.1 KFP06202.1 - 0.38 10.3 8.4 2.1 8.0 2.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain C1_1 PF00130.17 KFP06202.1 - 0.93 9.2 6.1 12 5.7 0.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FAD-oxidase_C PF02913.14 KFP06203.1 - 4.2e-47 160.5 0.0 6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFP06203.1 - 6.5e-08 32.1 0.2 1.4e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Anth_Ig PF05587.8 KFP06204.1 - 9.2e-49 163.6 0.4 1.3e-48 163.1 0.3 1.2 1 0 0 1 1 1 1 Anthrax receptor extracellular domain VWA PF00092.23 KFP06204.1 - 9.7e-22 77.5 0.0 1.3e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFP06204.1 - 6.2e-16 58.9 0.0 7.9e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFP06204.1 - 1.5e-06 27.5 0.0 2.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein RhoGAP PF00620.22 KFP06205.1 - 3.8e-43 146.7 1.9 1.5e-42 144.8 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KFP06205.1 - 1.8e-15 57.0 0.0 5.5e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFP06205.1 - 6e-05 23.2 2.5 6e-05 23.2 1.7 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KFP06205.1 - 9.9e-05 22.3 0.0 0.0049 16.9 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain CENP-F_leu_zip PF10473.4 KFP06205.1 - 0.01 15.7 23.0 0.02 14.7 15.9 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.8 KFP06205.1 - 0.013 15.0 13.4 0.027 14.1 8.4 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region Tropomyosin_1 PF12718.2 KFP06205.1 - 0.031 14.1 20.0 0.052 13.3 13.9 1.3 1 0 0 1 1 1 0 Tropomyosin like B PF02216.11 KFP06205.1 - 0.19 11.5 2.3 0.46 10.2 1.6 1.6 1 0 0 1 1 1 0 B domain DUF2951 PF11166.3 KFP06205.1 - 2.2 8.2 15.4 4.7 7.1 10.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) AAA_13 PF13166.1 KFP06205.1 - 6.4 5.1 16.7 8.9 4.6 11.6 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KFP06205.1 - 6.9 6.2 16.9 0.88 9.1 8.5 1.8 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 KFP06205.1 - 9.9 5.0 18.5 15 4.4 12.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CTP_transf_1 PF01148.15 KFP06206.1 - 9.8e-90 300.7 25.8 1.2e-89 300.4 17.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PCNA_C PF02747.10 KFP06207.1 - 3.7e-68 227.3 0.0 6.8e-68 226.4 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 KFP06207.1 - 7.7e-62 206.4 0.9 1.4e-61 205.5 0.6 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 KFP06207.1 - 8.8e-08 31.5 0.0 1e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KFP06207.1 - 1.4e-07 30.6 0.0 6.8e-06 25.0 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 KFP06207.1 - 0.012 14.6 0.0 0.15 10.9 0.0 2.2 1 1 0 2 2 2 0 Hus1-like protein DUF872 PF05915.7 KFP06208.1 - 9e-28 96.4 0.8 1.1e-27 96.1 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) UbiA PF01040.13 KFP06208.1 - 0.013 14.7 0.9 0.015 14.5 0.6 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF308 PF03729.8 KFP06208.1 - 0.033 14.1 11.0 0.05 13.5 6.9 1.7 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Pox_A14 PF05767.7 KFP06208.1 - 0.07 13.0 0.9 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF973 PF06157.6 KFP06208.1 - 0.23 10.4 4.9 0.3 10.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF1700 PF08006.6 KFP06208.1 - 0.23 10.7 2.9 0.3 10.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Neurensin PF14927.1 KFP06208.1 - 0.33 10.3 3.5 0.48 9.8 0.1 2.0 1 1 1 2 2 2 0 Neurensin RseC_MucC PF04246.7 KFP06208.1 - 0.93 9.0 4.3 1.2 8.6 3.0 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SdpI PF13630.1 KFP06208.1 - 2.4 7.9 7.9 3.3 7.4 5.5 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family Tetraspannin PF00335.15 KFP06208.1 - 2.7 7.1 5.0 3.5 6.8 3.5 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2627 PF11118.3 KFP06208.1 - 5.2 7.2 7.8 1.1 9.4 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Xan_ur_permease PF00860.15 KFP06209.1 - 5.2e-92 308.3 20.6 7.6e-92 307.7 14.2 1.2 1 0 0 1 1 1 1 Permease family RA PF00788.18 KFP06210.1 - 1.8e-12 47.5 0.0 3.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFP06210.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Ras-binding domain of Byr2 Prominin PF05478.6 KFP06211.1 - 2.8e-129 432.0 0.0 3.6e-129 431.6 0.0 1.0 1 0 0 1 1 1 1 Prominin USP8_dimer PF08969.6 KFP06212.1 - 1.5e-19 69.9 0.2 1.5e-19 69.9 0.1 2.1 2 1 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.16 KFP06212.1 - 2.7e-19 68.9 0.1 2.7e-19 68.9 0.0 2.2 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KFP06212.1 - 9.7e-08 31.5 0.6 6.5e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain LIN37 PF15306.1 KFP06212.1 - 0.63 10.0 9.5 0.055 13.4 3.0 1.9 1 1 0 1 1 1 0 LIN37 DUF572 PF04502.8 KFP06212.1 - 0.77 8.9 11.4 1.1 8.3 7.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3959 PF13105.1 KFP06212.1 - 4.8 6.4 5.2 7.5 5.8 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Actin PF00022.14 KFP06213.1 - 1.7e-161 537.0 0.0 2e-161 536.8 0.0 1.0 1 0 0 1 1 1 1 Actin dNK PF01712.14 KFP06214.1 - 1.1e-26 93.5 0.0 1.3e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 KFP06214.1 - 0.019 15.2 0.2 0.047 13.9 0.1 1.7 1 1 1 2 2 2 0 AAA domain Yae1_N PF09811.4 KFP06215.1 - 2.6e-20 71.6 64.3 1.5e+04 -24.9 44.6 5.7 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Tet_JBP PF12851.2 KFP06216.1 - 8e-72 240.0 0.0 1.1e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Ras PF00071.17 KFP06217.1 - 1.9e-43 147.6 0.5 2.2e-43 147.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06217.1 - 1.9e-13 50.9 0.1 3.5e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06217.1 - 2.5e-05 23.6 0.1 2.6e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP06217.1 - 2.6e-05 23.7 0.1 3.2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP06217.1 - 0.006 16.5 0.1 0.0086 16.0 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFP06217.1 - 0.06 12.5 0.1 0.11 11.7 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit UBA PF00627.26 KFP06218.1 - 3.3e-25 87.2 0.0 5.1e-08 32.5 0.0 3.8 3 0 0 3 3 3 3 UBA/TS-N domain UBA_4 PF14555.1 KFP06218.1 - 3.8e-05 23.1 0.1 0.33 10.5 0.0 3.4 3 0 0 3 3 3 2 UBA-like domain Rap1_C PF11626.3 KFP06218.1 - 0.0005 19.8 0.0 5.2 7.0 0.0 3.6 3 0 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain ubiquitin PF00240.18 KFP06218.1 - 0.001 18.4 2.0 0.0057 16.0 1.4 2.3 2 0 0 2 2 2 1 Ubiquitin family TPR_2 PF07719.12 KFP06218.1 - 0.017 14.9 9.0 1.1 9.3 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RuvA_C PF07499.8 KFP06218.1 - 0.043 13.9 0.1 20 5.4 0.0 3.5 3 0 0 3 3 3 0 RuvA, C-terminal domain TPR_12 PF13424.1 KFP06218.1 - 0.13 12.2 6.3 8.1 6.4 0.3 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat UBA_3 PF09288.5 KFP06218.1 - 0.3 10.6 4.3 10 5.8 0.0 3.8 4 0 0 4 4 4 0 Fungal ubiquitin-associated domain TPR_1 PF00515.23 KFP06218.1 - 1.3 8.8 4.3 5.6 6.7 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FGGY_N PF00370.16 KFP06220.1 - 1.8e-21 76.5 0.0 1.2e-13 50.9 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KFP06220.1 - 1.9e-10 40.6 0.0 5.4e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_C PF02782.11 KFP06221.1 - 1.2e-11 44.5 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.20 KFP06224.1 - 5.8e-56 189.5 0.0 7.8e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06224.1 - 5.1e-26 91.2 0.0 8.3e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 KFP06224.1 - 2e-11 44.3 13.6 2e-11 44.3 9.4 2.1 2 0 0 2 2 2 1 Activin types I and II receptor domain Endonuclease_NS PF01223.18 KFP06225.1 - 2.2e-52 177.7 0.0 2.8e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease UQ_con PF00179.21 KFP06226.1 - 1.4e-47 160.6 0.1 1.5e-47 160.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP06226.1 - 0.00017 21.3 0.0 0.00019 21.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFP06226.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFP06226.1 - 0.03 14.0 0.1 0.049 13.3 0.1 1.3 1 1 0 1 1 1 0 UEV domain TMEM173 PF15009.1 KFP06227.1 - 2.6e-90 302.3 0.1 3.2e-90 302.0 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 173 LRR_4 PF12799.2 KFP06228.1 - 1.6e-20 72.2 13.4 1.5e-06 27.7 0.5 4.8 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP06228.1 - 4.6e-18 64.7 11.1 1.7e-07 30.8 1.6 4.3 2 2 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 KFP06228.1 - 3e-10 39.0 8.8 0.89 9.8 0.0 7.1 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 KFP06228.1 - 6.6e-09 34.5 18.7 0.31 11.2 0.2 8.0 7 1 1 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 KFP06228.1 - 3.1e-07 29.5 16.1 0.75 10.2 0.1 7.5 6 1 1 7 7 7 2 Leucine rich repeat LRRCT PF01463.19 KFP06228.1 - 0.068 13.4 2.6 0.29 11.5 0.1 3.5 4 0 0 4 4 4 0 Leucine rich repeat C-terminal domain Proteasom_PSMB PF10508.4 KFP06229.1 - 0.00073 17.9 0.8 0.012 13.8 0.1 2.7 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 KFP06229.1 - 0.0012 19.0 9.8 1.4 9.2 0.0 4.0 3 1 1 4 4 4 3 HEAT repeats Arm PF00514.18 KFP06229.1 - 0.074 12.9 0.2 0.074 12.9 0.1 6.8 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat DUF2454 PF10521.4 KFP06229.1 - 0.83 8.5 11.3 0.17 10.8 0.1 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF2454) HEAT PF02985.17 KFP06229.1 - 3.2 8.0 14.3 1.6 8.9 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat L51_S25_CI-B8 PF05047.11 KFP06230.1 - 1.3e-17 63.2 0.0 1.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain WD40 PF00400.27 KFP06231.1 - 4e-25 86.7 0.1 0.00012 21.8 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFP06231.1 - 0.0061 15.3 0.0 0.09 11.5 0.0 2.1 2 0 0 2 2 2 1 Nup133 N terminal like BBS2_Mid PF14783.1 KFP06231.1 - 0.012 15.3 0.0 0.077 12.7 0.0 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region RRM_1 PF00076.17 KFP06232.1 - 6.5e-05 22.4 0.0 9.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP06232.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) B12-binding_2 PF02607.12 KFP06232.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain tRNA-synt_His PF13393.1 KFP06233.1 - 1.1e-32 113.3 0.0 1.5e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 KFP06233.1 - 2e-13 50.0 0.0 3.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 KFP06233.1 - 4.1e-12 46.0 0.0 6.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.2 KFP06233.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.15 KFP06233.1 - 0.027 13.2 0.0 0.39 9.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) zf-C2H2_jaz PF12171.3 KFP06234.1 - 6.3e-07 29.3 1.2 1.4e-06 28.2 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP06234.1 - 2.5e-06 27.4 1.3 4e-06 26.8 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 KFP06234.1 - 0.00013 21.4 1.0 0.00022 20.7 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger DUF1777 PF08648.7 KFP06234.1 - 0.003 17.3 12.1 0.003 17.3 8.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Cgr1 PF03879.9 KFP06234.1 - 0.0057 16.8 18.0 0.0057 16.8 12.5 2.3 2 0 0 2 2 2 1 Cgr1 family CCDC84 PF14968.1 KFP06234.1 - 0.12 11.8 12.4 0.03 13.8 4.9 1.9 1 1 1 2 2 2 0 Coiled coil protein 84 CAF-1_p150 PF11600.3 KFP06234.1 - 0.99 8.7 31.9 0.018 14.4 12.7 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF87 PF01935.12 KFP06234.1 - 1.9 8.2 6.2 2.4 7.9 4.3 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF3959 PF13105.1 KFP06234.1 - 4.2 6.6 6.3 6.7 5.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Caldesmon PF02029.10 KFP06234.1 - 5.9 5.1 25.6 0.21 9.9 11.7 1.9 2 0 0 2 2 2 0 Caldesmon PID PF00640.18 KFP06237.1 - 2e-48 163.9 0.0 1.1e-28 99.9 0.0 2.1 2 0 0 2 2 2 2 Phosphotyrosine interaction domain (PTB/PID) WW PF00397.21 KFP06237.1 - 4.6e-06 26.3 5.4 1e-05 25.2 3.8 1.7 1 0 0 1 1 1 1 WW domain PTB PF08416.8 KFP06237.1 - 1.1e-05 25.3 0.0 3.4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotyrosine-binding domain SRA1 PF07304.6 KFP06238.1 - 1.5e-51 174.2 0.0 1.9e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Se-cys_synth_N PF12390.3 KFP06238.1 - 0.0041 17.1 1.2 2 8.5 0.0 2.8 3 0 0 3 3 3 2 Selenocysteine synthase N terminal eIF_4EBP PF05456.6 KFP06239.1 - 3.2e-17 62.2 0.1 3.4e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) HCO3_cotransp PF00955.16 KFP06240.1 - 7.9e-221 734.1 0.5 9.7e-221 733.8 0.3 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFP06240.1 - 2.4e-67 227.1 0.0 3.6e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain EGF PF00008.22 KFP06241.1 - 1.3e-05 25.0 5.2 2.8e-05 23.9 3.6 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFP06241.1 - 0.00046 20.0 3.0 0.0011 18.9 2.1 1.7 1 0 0 1 1 1 1 Human growth factor-like EGF CD34_antigen PF06365.7 KFP06241.1 - 0.065 12.8 0.1 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family AP_endonuc_2 PF01261.19 KFP06241.1 - 0.088 12.0 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Laminin_EGF PF00053.19 KFP06241.1 - 2.5 8.1 6.0 7.4 6.5 4.1 1.9 1 1 0 1 1 1 0 Laminin EGF-like (Domains III and V) Prefoldin_2 PF01920.15 KFP06242.1 - 8.4e-20 70.5 13.0 9.4e-20 70.3 9.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.4 KFP06242.1 - 0.017 14.6 3.9 0.019 14.4 2.7 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein Mvb12 PF09452.5 KFP06242.1 - 0.52 10.5 2.7 5.7 7.1 0.1 2.1 1 1 0 2 2 2 0 ESCRT-I subunit Mvb12 IncA PF04156.9 KFP06242.1 - 0.93 9.0 7.7 3.6 7.1 0.7 2.1 2 0 0 2 2 2 0 IncA protein Neuregulin PF02158.10 KFP06244.1 - 5.9e-97 324.9 16.8 8.5e-97 324.4 11.7 1.2 1 0 0 1 1 1 1 Neuregulin family I-set PF07679.11 KFP06244.1 - 6.7e-18 64.3 0.0 1.3e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP06244.1 - 2.8e-13 49.7 0.2 2e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.20 KFP06244.1 - 6.7e-13 48.5 0.0 1.9e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP06244.1 - 2.1e-07 31.3 0.0 1.3e-06 28.7 0.0 2.4 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP06244.1 - 2e-06 27.6 0.1 1.1e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP06244.1 - 0.0012 18.6 0.0 0.0042 16.9 0.0 1.9 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain hEGF PF12661.2 KFP06244.1 - 0.045 13.8 3.3 0.13 12.4 2.3 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 KFP06244.1 - 0.86 9.8 9.5 4.6 7.4 6.6 2.4 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 KFP06244.1 - 0.95 9.5 9.8 0.45 10.5 4.8 2.1 2 0 0 2 2 2 0 EGF-like domain Sec7 PF01369.15 KFP06245.1 - 2.7e-50 170.6 1.3 2.7e-50 170.6 0.1 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 KFP06245.1 - 8.6e-38 129.1 3.4 1.2e-37 128.7 0.1 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 KFP06245.1 - 4.6e-12 46.0 0.1 1.2e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 PH domain zf-CXXC PF02008.15 KFP06246.1 - 1.4e-07 31.1 23.5 2.3e-07 30.5 16.3 1.3 1 0 0 1 1 1 1 CXXC zinc finger domain RsbRD_N PF14361.1 KFP06246.1 - 0.035 14.5 0.1 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain QueC PF06508.8 KFP06246.1 - 3.7 6.7 11.3 2.1 7.5 0.6 2.3 1 1 1 2 2 2 0 Queuosine biosynthesis protein QueC zf-RING_2 PF13639.1 KFP06247.1 - 1e-13 50.8 6.4 1.8e-13 50.0 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFP06247.1 - 4.4e-09 35.9 0.2 1.1e-08 34.6 0.1 1.7 1 1 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KFP06247.1 - 3.7e-08 33.3 2.3 7.7e-08 32.3 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFP06247.1 - 7.2e-08 31.9 3.6 1.2e-07 31.2 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP06247.1 - 1.6e-07 30.8 4.7 2.8e-07 30.0 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP06247.1 - 3.2e-07 29.9 4.0 5.3e-07 29.2 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFP06247.1 - 6.3e-07 29.3 6.8 1.2e-06 28.4 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UPF0233 PF06781.7 KFP06247.1 - 0.0044 16.5 0.5 0.01 15.4 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0233) zf-Apc11 PF12861.2 KFP06247.1 - 0.0081 15.9 2.3 0.015 15.0 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ninjurin PF04923.7 KFP06247.1 - 0.017 14.8 0.5 0.037 13.7 0.3 1.5 1 0 0 1 1 1 0 Ninjurin PspB PF06667.7 KFP06247.1 - 0.027 14.4 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Phage shock protein B MSC PF09402.5 KFP06247.1 - 0.071 11.8 0.2 0.15 10.7 0.1 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PgaD PF13994.1 KFP06247.1 - 0.076 12.4 0.4 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 PgaD-like protein BatD PF13584.1 KFP06247.1 - 0.079 11.5 0.2 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance RINGv PF12906.2 KFP06247.1 - 0.16 12.0 4.2 0.31 11.0 2.9 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KFP06247.1 - 0.29 10.8 4.2 0.58 9.9 2.9 1.5 1 0 0 1 1 1 0 PHD-finger NOA36 PF06524.7 KFP06249.1 - 7.1e-165 547.8 43.1 8e-165 547.6 29.9 1.0 1 0 0 1 1 1 1 NOA36 protein IL15 PF02372.10 KFP06250.1 - 1.7e-41 141.1 11.7 2e-41 140.9 8.1 1.0 1 0 0 1 1 1 1 Interleukin 15 UCH PF00443.24 KFP06252.1 - 7.3e-47 159.7 0.9 1.1e-46 159.1 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP06252.1 - 2.4e-23 83.0 0.0 6.4e-23 81.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PH PF00169.24 KFP06253.1 - 2.3e-16 59.8 0.2 1.1e-15 57.7 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFP06253.1 - 3.1e-07 30.6 0.4 1.4e-06 28.4 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFP06253.1 - 0.051 13.4 0.3 0.15 12.0 0.2 1.7 1 1 0 1 1 1 0 PH domain SNF2_N PF00176.18 KFP06254.1 - 3.1e-85 285.5 0.5 6.4e-85 284.5 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 KFP06254.1 - 6.9e-44 148.3 2.1 2.4e-43 146.6 1.5 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KFP06254.1 - 1e-28 100.0 1.8 1e-28 100.0 1.3 2.9 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KFP06254.1 - 6.2e-16 58.0 0.0 2.4e-15 56.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP06254.1 - 2.4e-08 34.0 0.0 3.8e-07 30.1 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFP06254.1 - 6.5e-08 32.2 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 KFP06254.1 - 0.00026 20.9 0.1 0.79 9.8 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain DBINO PF13892.1 KFP06254.1 - 0.0011 18.9 0.3 0.0011 18.9 0.2 3.6 3 0 0 3 3 3 1 DNA-binding domain AAA_22 PF13401.1 KFP06254.1 - 0.1 12.7 0.0 2.5 8.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain GSDH PF07995.6 KFP06255.1 - 2.7e-18 66.1 0.0 4.1e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase EGF_2 PF07974.8 KFP06255.1 - 0.00055 20.0 8.0 0.00055 20.0 5.5 3.5 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.2 KFP06255.1 - 1.1 9.5 14.5 1.4 9.1 0.9 3.4 2 0 0 2 2 2 0 Human growth factor-like EGF APC10 PF03256.11 KFP06256.1 - 3.1e-79 265.0 0.1 3.6e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) CHB_HEX_C_1 PF13290.1 KFP06256.1 - 0.0057 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain PITH PF06201.8 KFP06256.1 - 0.018 14.7 0.1 0.075 12.8 0.1 1.8 1 1 0 1 1 1 0 PITH domain ABC_tran PF00005.22 KFP06257.1 - 6.2e-38 130.2 0.0 1.2e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 KFP06257.1 - 9.2e-15 53.9 7.3 2.6e-14 52.4 5.1 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KFP06257.1 - 4.7e-12 46.4 3.5 0.041 13.8 0.1 4.9 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 KFP06257.1 - 1.4e-10 40.7 3.3 0.0019 17.5 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFP06257.1 - 1e-08 34.6 0.2 0.21 10.6 0.0 4.2 4 0 0 4 4 4 3 AAA ATPase domain AAA_16 PF13191.1 KFP06257.1 - 2.6e-08 34.0 0.0 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.22 KFP06257.1 - 7.3e-07 28.5 1.7 7.3e-07 28.5 1.2 3.5 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_22 PF13401.1 KFP06257.1 - 2.7e-06 27.5 0.1 0.0022 18.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFP06257.1 - 1.3e-05 24.6 0.1 0.061 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 KFP06257.1 - 2.2e-05 24.6 0.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KFP06257.1 - 4.1e-05 22.8 2.6 0.083 12.0 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFP06257.1 - 7.4e-05 23.5 0.3 0.59 10.9 0.1 3.0 2 2 0 2 2 2 2 AAA domain Miro PF08477.8 KFP06257.1 - 0.00013 22.4 0.6 0.62 10.5 0.0 3.5 3 1 0 3 3 3 1 Miro-like protein NACHT PF05729.7 KFP06257.1 - 0.00013 21.6 0.5 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Fer4_6 PF12837.2 KFP06257.1 - 0.00017 21.3 1.2 0.00017 21.3 0.8 3.2 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_33 PF13671.1 KFP06257.1 - 0.00052 19.9 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFP06257.1 - 0.00055 20.2 0.0 0.45 10.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFP06257.1 - 0.0012 18.2 0.0 0.54 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFP06257.1 - 0.0018 17.9 0.4 0.39 10.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KFP06257.1 - 0.002 18.4 0.1 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFP06257.1 - 0.002 18.2 0.0 1.8 8.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase Fer4_21 PF14697.1 KFP06257.1 - 0.0026 17.5 1.5 0.0026 17.5 1.1 2.4 2 1 2 4 4 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFP06257.1 - 0.0026 17.5 2.0 0.0026 17.5 1.4 3.1 3 0 0 3 3 2 1 4Fe-4S binding domain SRP54 PF00448.17 KFP06257.1 - 0.0029 17.0 1.9 0.28 10.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain VirE PF05272.6 KFP06257.1 - 0.0043 16.5 0.0 0.98 8.8 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_7 PF12838.2 KFP06257.1 - 0.0052 17.1 1.6 0.0052 17.1 1.1 3.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain UPF0079 PF02367.12 KFP06257.1 - 0.0062 16.1 0.2 0.089 12.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_10 PF13237.1 KFP06257.1 - 0.014 15.1 2.0 0.014 15.1 1.4 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 KFP06257.1 - 0.017 14.6 0.5 0.33 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFP06257.1 - 0.018 14.9 0.1 3.4 7.6 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 KFP06257.1 - 0.021 15.5 0.6 0.021 15.5 0.4 3.0 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 KFP06257.1 - 0.021 14.7 0.4 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 KFP06257.1 - 0.024 14.9 2.2 0.024 14.9 1.6 3.2 2 1 1 3 3 3 0 4Fe-4S dicluster domain Rad17 PF03215.10 KFP06257.1 - 0.051 12.2 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KFP06257.1 - 0.058 12.2 0.1 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 KFP06257.1 - 0.062 12.0 0.2 6.3 5.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 KFP06257.1 - 0.068 12.8 1.1 0.95 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFP06257.1 - 0.093 12.2 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFP06257.1 - 0.13 12.2 0.0 18 5.2 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFP06257.1 - 0.2 11.0 0.3 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Fer4_8 PF13183.1 KFP06257.1 - 0.45 10.5 11.1 0.11 12.5 1.0 2.5 2 1 1 3 3 2 0 4Fe-4S dicluster domain AAA_10 PF12846.2 KFP06257.1 - 1.7 8.0 4.9 11 5.3 0.1 2.8 3 1 0 3 3 3 0 AAA-like domain OTU PF02338.14 KFP06258.1 - 4.1e-16 59.6 0.1 9.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFP06258.1 - 0.0011 18.3 0.1 0.22 10.8 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain SMN PF06003.7 KFP06258.1 - 0.012 14.7 0.0 0.012 14.7 0.0 3.5 5 0 0 5 5 5 0 Survival motor neuron protein (SMN) MH2 PF03166.9 KFP06259.1 - 2.4e-45 154.6 0.1 3.4e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFP06259.1 - 2.1e-42 143.3 1.2 4.4e-42 142.2 0.8 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFP06259.1 - 2.5e-05 23.9 0.9 5.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Interferon-regulatory factor 3 DUF605 PF04652.11 KFP06259.1 - 0.47 9.8 8.6 0.5 9.7 5.9 1.1 1 0 0 1 1 1 0 Vta1 like ArgK PF03308.11 KFP06260.1 - 7.7e-95 316.6 0.2 1e-94 316.2 0.1 1.2 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 KFP06260.1 - 1.2e-05 24.7 0.0 6e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KFP06260.1 - 3.3e-05 24.0 0.8 0.0037 17.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 KFP06260.1 - 0.00034 20.2 0.0 0.0008 19.0 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.1 KFP06260.1 - 0.002 18.0 0.0 0.096 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFP06260.1 - 0.0044 17.3 0.0 0.014 15.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KFP06260.1 - 0.0053 16.4 0.2 0.028 14.1 0.0 2.3 3 0 0 3 3 3 1 Part of AAA domain CbiA PF01656.18 KFP06260.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 KFP06260.1 - 0.0074 16.2 0.5 0.037 14.0 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KFP06260.1 - 0.0089 15.7 0.1 0.059 13.0 0.0 2.2 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KFP06260.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KFP06260.1 - 0.011 15.5 0.1 0.067 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFP06260.1 - 0.027 14.7 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KFP06260.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFP06260.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 KFP06260.1 - 0.03 13.6 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase NTPase_1 PF03266.10 KFP06260.1 - 0.031 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 KFP06260.1 - 0.04 14.7 0.0 0.13 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KFP06260.1 - 0.05 12.7 0.1 0.41 9.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.9 KFP06260.1 - 0.054 12.4 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.18 KFP06260.1 - 0.092 12.7 0.0 0.28 11.1 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 KFP06260.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFP06260.1 - 0.13 11.7 0.0 0.52 9.7 0.0 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 KFP06260.1 - 0.17 12.0 0.0 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase zf-C2H2 PF00096.21 KFP06261.1 - 2e-14 52.9 80.2 0.00025 21.2 0.2 9.2 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP06261.1 - 4.7e-12 45.5 73.1 0.00054 20.1 3.2 11.1 11 1 0 11 11 11 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP06261.1 - 2.2e-11 43.2 74.0 0.0048 17.1 3.7 9.4 9 0 0 9 9 9 6 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP06261.1 - 7.6e-09 35.2 77.3 0.021 15.0 4.0 8.9 8 0 0 8 8 8 5 C2H2-type zinc-finger domain zf-met PF12874.2 KFP06261.1 - 0.0085 16.2 64.4 0.39 11.0 1.8 9.1 9 0 0 9 9 8 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP06261.1 - 0.014 15.3 0.2 0.014 15.3 0.1 5.1 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP06261.1 - 0.37 10.9 0.0 0.079 13.1 0.4 7.8 9 0 0 9 9 7 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KFP06261.1 - 0.81 9.3 0.0 0.81 9.3 0.0 4.8 5 0 0 5 5 5 0 GAGA factor zf-C2H2_7 PF15269.1 KFP06261.1 - 6.4 6.7 44.3 0.14 12.0 0.8 7.5 5 2 3 8 8 8 0 Zinc-finger zf-Sec23_Sec24 PF04810.10 KFP06261.1 - 8 6.1 22.0 11 5.7 0.0 6.8 7 1 1 8 8 8 0 Sec23/Sec24 zinc finger DUF899 PF05988.7 KFP06261.1 - 9 5.6 10.1 0.12 11.7 0.3 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF899) LSM PF01423.17 KFP06262.1 - 5.4e-18 64.2 0.1 6.2e-18 64.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFP06262.1 - 2.5e-05 24.1 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Reeler PF02014.11 KFP06263.1 - 8.5e-32 110.1 0.0 9.9e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Reeler domain DUF4137 PF13593.1 KFP06264.1 - 8.9e-74 248.3 21.8 1e-73 248.2 15.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KFP06264.1 - 3.6e-15 55.8 13.4 3.6e-15 55.8 9.3 2.3 2 1 0 3 3 3 1 Sodium Bile acid symporter family MRAP PF15183.1 KFP06264.1 - 2.8 7.5 6.3 0.17 11.4 0.3 2.0 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Pou PF00157.12 KFP06265.1 - 1.5e-31 107.8 0.0 2.7e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeobox PF00046.24 KFP06265.1 - 9.2e-18 63.6 1.8 2.4e-17 62.3 1.3 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_31 PF13560.1 KFP06265.1 - 0.00027 21.0 0.0 0.007 16.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 KFP06265.1 - 0.00078 19.4 0.0 0.042 13.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Homeobox_KN PF05920.6 KFP06265.1 - 0.024 14.3 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain TPR_11 PF13414.1 KFP06266.1 - 1.2e-12 47.2 8.1 0.00057 19.4 0.2 4.2 4 0 0 4 4 4 3 TPR repeat TPR_12 PF13424.1 KFP06266.1 - 3.2e-11 43.0 11.5 1.6e-05 24.7 0.5 4.2 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KFP06266.1 - 2.7e-07 29.8 2.1 0.007 16.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFP06266.1 - 3.3e-07 29.7 10.5 0.33 10.9 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFP06266.1 - 1.1e-06 27.9 9.2 0.029 13.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP06266.1 - 0.00026 21.3 4.8 11 6.9 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP06266.1 - 0.00031 20.5 1.0 0.053 13.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP06266.1 - 0.001 18.7 9.1 0.54 10.1 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFP06266.1 - 0.0095 16.0 4.4 24 5.4 0.0 4.9 5 1 0 5 5 4 0 Tetratricopeptide repeat Cation_ATPase_N PF00690.21 KFP06266.1 - 0.073 12.5 0.4 2.9 7.4 0.0 2.8 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Cap_synth_GfcB PF11102.3 KFP06266.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Group 4 capsule polysaccharide formation lipoprotein gfcB SHNi-TPR PF10516.4 KFP06266.1 - 0.088 12.0 0.1 2.2 7.6 0.0 2.8 2 0 0 2 2 2 0 SHNi-TPR TPR_4 PF07721.9 KFP06266.1 - 0.16 12.5 2.9 58 4.5 0.2 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFP06266.1 - 2.4 8.8 7.0 37 5.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFP06266.1 - 2.8 8.1 12.4 10 6.2 0.1 5.3 5 2 2 7 7 7 0 Tetratricopeptide repeat 7tm_1 PF00001.16 KFP06268.1 - 2.7e-38 131.6 10.0 2.7e-38 131.6 7.0 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06268.1 - 0.0024 17.0 14.0 0.12 11.4 8.8 3.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Solute_trans_a PF03619.11 KFP06269.1 - 1.1e-99 333.2 17.4 1.3e-99 333.0 12.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-C4 PF00105.13 KFP06270.1 - 1.2e-28 99.0 12.9 2.2e-28 98.2 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFP06270.1 - 3.1e-14 52.5 0.0 5.8e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Lipase_GDSL_2 PF13472.1 KFP06271.1 - 2.4e-07 31.0 0.0 5.3e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.20 KFP06272.1 - 1.4e-72 243.9 0.0 2.1e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DCX PF03607.12 KFP06272.1 - 1e-45 153.1 0.1 8e-24 83.0 0.0 2.7 2 0 0 2 2 2 2 Doublecortin Pkinase_Tyr PF07714.12 KFP06272.1 - 4.2e-33 114.5 0.0 6.5e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06272.1 - 0.0015 17.5 0.0 0.0037 16.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFP06272.1 - 0.038 13.3 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KFP06272.1 - 0.059 12.4 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mab-21 PF03281.9 KFP06273.1 - 1.7e-89 299.8 0.0 2.3e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein Beach PF02138.13 KFP06274.1 - 1.2e-113 379.1 0.1 2.2e-113 378.1 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.16 KFP06274.1 - 6.3e-16 58.0 9.7 1.5e-15 56.7 6.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.1 KFP06274.1 - 9.1e-15 54.4 0.0 2.8e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KFP06274.1 - 5e-14 51.5 11.8 3.1e-08 33.1 0.3 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Laminin_G_3 PF13385.1 KFP06274.1 - 1.9e-06 28.1 0.0 4.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CTP_transf_1 PF01148.15 KFP06276.1 - 7.9e-87 291.1 25.0 9.8e-87 290.8 17.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Acyltransferase PF01553.16 KFP06278.1 - 7.3e-19 67.5 0.1 1.4e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase ELFV_dehydrog_N PF02812.13 KFP06278.1 - 0.083 12.4 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Acyltransferase PF01553.16 KFP06279.1 - 1.6e-11 43.7 0.0 2.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Tropomyosin PF00261.15 KFP06280.1 - 0.00017 20.7 1.3 0.00017 20.7 0.9 2.0 2 0 0 2 2 2 1 Tropomyosin DUF3199 PF11436.3 KFP06280.1 - 0.0087 15.9 0.1 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3199) DUF2096 PF09869.4 KFP06280.1 - 0.045 13.6 0.2 0.045 13.6 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) DUF948 PF06103.6 KFP06280.1 - 0.053 13.3 2.7 0.16 11.8 1.8 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2508 PF10704.4 KFP06280.1 - 6.3 7.0 7.2 9.9 6.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Ribosomal_S18 PF01084.15 KFP06281.1 - 6e-23 80.4 0.1 2.2e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 Ribosomal_S5 PF00333.15 KFP06281.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Glyco_hydro_79n PF03662.9 KFP06282.1 - 3.8e-24 84.8 0.1 2.9e-23 82.0 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain UbiA PF01040.13 KFP06283.1 - 6e-34 117.4 10.4 8.6e-34 116.9 7.2 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4018 PF13210.1 KFP06283.1 - 0.021 14.1 0.4 0.089 12.1 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4018) PepSY_TM PF03929.11 KFP06283.1 - 0.43 11.0 0.0 0.43 11.0 0.0 4.1 4 0 0 4 4 4 0 PepSY-associated TM helix PepSY_TM_1 PF13172.1 KFP06283.1 - 6.9 6.5 9.0 0.12 12.1 0.8 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix PLAC8 PF04749.12 KFP06284.1 - 4.8e-15 56.0 18.3 2.5e-14 53.7 12.7 1.8 1 1 0 1 1 1 1 PLAC8 family ABC2_membrane PF01061.19 KFP06285.1 - 4e-34 117.6 23.1 4e-34 117.6 16.0 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KFP06285.1 - 3.8e-22 79.0 0.1 8.4e-22 77.9 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 KFP06285.1 - 3.4e-08 33.7 0.1 0.0036 17.3 0.1 2.6 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 KFP06285.1 - 3.5e-05 23.1 0.1 0.031 13.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFP06285.1 - 4.9e-05 23.7 0.7 0.00029 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KFP06285.1 - 0.00079 18.5 0.3 1.6 7.6 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KFP06285.1 - 0.0063 17.3 0.0 0.061 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFP06285.1 - 0.0074 15.8 0.1 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KFP06285.1 - 0.016 14.2 27.2 0.036 13.0 18.8 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_16 PF13191.1 KFP06285.1 - 0.026 14.5 0.0 0.05 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KFP06285.1 - 0.048 13.9 0.1 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFP06285.1 - 0.088 12.9 0.2 0.51 10.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFP06285.1 - 0.13 12.1 0.1 0.48 10.3 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KFP06285.1 - 0.18 11.5 1.1 0.41 10.4 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 PKD_channel PF08016.7 KFP06286.1 - 6.2e-158 525.6 18.1 7.3e-158 525.4 12.5 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KFP06286.1 - 3.5e-23 81.8 27.7 7.1e-23 80.8 19.2 1.5 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.27 KFP06286.1 - 0.00047 19.2 1.0 0.038 13.2 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KFP06286.1 - 0.0033 17.1 0.9 0.073 12.9 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KFP06286.1 - 0.0091 15.5 0.6 0.022 14.3 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KFP06286.1 - 0.024 14.7 0.5 0.058 13.5 0.4 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF445 PF04286.7 KFP06286.1 - 0.09 12.2 0.2 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Osteopontin PF00865.13 KFP06287.1 - 2.4e-26 92.6 10.8 1.6e-16 60.3 0.7 2.0 1 1 1 2 2 2 2 Osteopontin LRR19-TM PF15176.1 KFP06287.1 - 0.35 10.5 2.7 0.67 9.6 1.9 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain BSP_II PF05432.6 KFP06289.1 - 5.5e-51 173.5 94.8 3.5e-25 88.8 2.0 3.2 2 1 0 2 2 2 2 Bone sialoprotein II (BSP-II) UPF0564 PF10595.4 KFP06289.1 - 0.053 12.4 9.8 0.074 11.9 6.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF605 PF04652.11 KFP06289.1 - 0.06 12.7 6.4 0.071 12.5 4.4 1.2 1 0 0 1 1 1 0 Vta1 like NAM-associated PF14303.1 KFP06289.1 - 0.57 10.4 12.6 1 9.6 8.7 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Nucleoplasmin PF03066.10 KFP06289.1 - 0.89 9.0 40.1 0.64 9.5 5.9 3.0 3 0 0 3 3 3 0 Nucleoplasmin Hid1 PF12722.2 KFP06289.1 - 1.1 6.8 6.8 1.3 6.6 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BAT2_N PF07001.6 KFP06289.1 - 1.8 8.8 10.2 0.25 11.6 3.7 2.0 1 1 1 2 2 2 0 BAT2 N-terminus SAPS PF04499.10 KFP06289.1 - 3.9 5.9 17.0 5.9 5.4 11.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC27 PF09507.5 KFP06289.1 - 5.4 6.1 24.0 8.4 5.4 16.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Utp14 PF04615.8 KFP06289.1 - 6.3 4.8 28.3 9.5 4.2 19.6 1.2 1 0 0 1 1 1 0 Utp14 protein DMP1 PF07263.6 KFP06290.1 - 1.2e-06 27.5 38.4 1.4e-06 27.3 26.6 1.0 1 0 0 1 1 1 1 Dentin matrix protein 1 (DMP1) Macoilin PF09726.4 KFP06290.1 - 2.9 6.0 16.9 2.9 6.0 11.7 1.0 1 0 0 1 1 1 0 Transmembrane protein SPARC_Ca_bdg PF10591.4 KFP06291.1 - 1.8e-40 137.5 0.7 3.1e-40 136.7 0.5 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_1 PF00050.16 KFP06291.1 - 6.6e-12 45.2 6.3 6.6e-12 45.2 4.4 2.2 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain FOLN PF09289.5 KFP06291.1 - 7.3e-10 38.5 11.0 7.3e-10 38.5 7.6 2.2 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain Kazal_2 PF07648.10 KFP06291.1 - 4.8e-09 36.0 3.0 4.8e-09 36.0 2.1 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.1 KFP06291.1 - 0.074 13.2 0.2 19 5.4 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair NUDIX PF00293.23 KFP06292.1 - 7.2e-11 41.8 0.3 3e-10 39.8 0.2 1.9 1 1 0 1 1 1 1 NUDIX domain Bcl-2 PF00452.14 KFP06293.1 - 1.4e-28 98.9 0.1 3.2e-28 97.8 0.0 1.6 2 0 0 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family Pkinase PF00069.20 KFP06294.1 - 1.2e-71 240.8 0.0 1.5e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06294.1 - 8.4e-53 179.0 0.0 1.3e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06294.1 - 0.0003 19.8 0.0 0.00092 18.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 KFP06294.1 - 0.0011 18.2 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) APH PF01636.18 KFP06294.1 - 0.032 13.9 0.0 0.58 9.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4288 PF14119.1 KFP06294.1 - 0.088 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) RhoGEF PF00621.15 KFP06295.1 - 1.3e-35 122.8 3.3 2.6e-35 121.9 2.3 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KFP06295.1 - 1.8e-26 92.3 0.6 5.7e-15 55.3 0.3 2.7 2 0 0 2 2 2 2 PH domain FERM_C PF09380.5 KFP06295.1 - 7.6e-26 90.1 0.2 1.7e-25 89.0 0.1 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFP06295.1 - 9.6e-18 64.0 0.1 3.7e-17 62.1 0.1 2.1 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.6 KFP06295.1 - 3.6e-13 49.0 0.9 9e-13 47.8 0.6 1.7 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.13 KFP06295.1 - 1e-08 35.3 0.0 2.9e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 FERM central domain PH_7 PF15408.1 KFP06295.1 - 0.0066 16.3 0.1 0.13 12.1 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KFP06295.1 - 0.078 13.2 7.2 11 6.2 1.2 4.2 3 2 0 3 3 3 0 Pleckstrin homology domain Septin PF00735.13 KFP06296.1 - 1.9e-126 420.8 0.1 2.6e-126 420.3 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFP06296.1 - 1.9e-07 31.0 0.0 4.8e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP06296.1 - 7.8e-06 25.4 0.1 0.0017 17.7 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFP06296.1 - 0.00013 21.8 1.6 0.023 14.5 0.0 3.0 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 KFP06296.1 - 0.00015 21.0 0.2 0.00039 19.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFP06296.1 - 0.00017 20.7 0.8 0.00037 19.6 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Ras PF00071.17 KFP06296.1 - 0.00048 19.5 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.1 KFP06296.1 - 0.0021 18.2 0.3 0.011 15.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 KFP06296.1 - 0.0047 16.4 0.0 0.0099 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain HrpB7 PF09486.5 KFP06296.1 - 0.0055 16.6 1.2 0.012 15.5 0.8 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Miro PF08477.8 KFP06296.1 - 0.0067 16.9 0.1 0.046 14.2 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KFP06296.1 - 0.011 14.8 0.2 0.17 11.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 KFP06296.1 - 0.013 15.8 1.2 0.021 15.1 0.1 1.9 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 KFP06296.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KFP06296.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KFP06296.1 - 0.077 12.7 0.5 0.16 11.6 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KFP06296.1 - 0.46 10.4 4.6 20 5.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KFP06296.1 - 0.9 9.8 6.5 10 6.3 4.5 2.1 1 1 0 1 1 1 0 AAA domain KH_1 PF00013.24 KFP06297.1 - 8.9e-188 608.1 61.0 1.7e-15 56.4 1.4 15.7 15 1 0 15 15 15 15 KH domain KH_3 PF13014.1 KFP06297.1 - 1.3e-129 420.3 56.6 3.4e-12 45.7 0.9 15.6 16 0 0 16 16 16 14 KH domain SLS PF14611.1 KFP06297.1 - 6.9e-26 90.9 19.4 7.5e-07 28.7 0.1 8.6 3 3 6 9 9 9 6 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KFP06297.1 - 1.2e-14 53.6 52.9 0.011 15.2 1.2 12.4 10 3 1 12 12 12 8 KH domain BMC PF00936.14 KFP06297.1 - 1.7e-09 37.1 4.1 3 7.5 0.0 9.7 11 0 0 11 11 11 1 BMC domain KH_5 PF13184.1 KFP06297.1 - 2.6e-08 33.5 24.1 2.3 8.1 0.0 11.2 12 0 0 12 12 12 4 NusA-like KH domain DUF2096 PF09869.4 KFP06297.1 - 2.1e-05 24.4 22.0 2.8 7.7 0.0 9.4 10 1 1 11 11 11 3 Uncharacterized protein conserved in archaea (DUF2096) Lactamase_B_4 PF13691.1 KFP06297.1 - 0.0084 15.5 0.0 10 5.6 0.0 3.7 3 0 0 3 3 3 1 tRNase Z endonuclease SCO1-SenC PF02630.9 KFP06297.1 - 0.051 13.1 2.6 5.2 6.6 0.1 3.4 2 0 0 2 2 2 0 SCO1/SenC LRR_4 PF12799.2 KFP06298.1 - 4.3e-40 134.7 43.6 6.5e-10 38.4 1.7 6.2 4 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP06298.1 - 9e-27 92.6 81.0 1e-08 34.8 4.6 5.0 2 1 5 7 7 7 7 Leucine rich repeat LRR_9 PF14580.1 KFP06298.1 - 1.8e-19 69.9 22.0 8.8e-09 35.1 4.1 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 KFP06298.1 - 1.9e-12 45.3 40.3 0.095 12.7 0.1 10.7 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 KFP06298.1 - 9.9e-09 34.3 30.1 0.095 12.8 0.3 10.1 7 4 1 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 KFP06298.1 - 8.9e-08 31.1 23.0 0.61 10.5 0.1 9.6 8 3 1 9 9 9 3 Leucine rich repeat DUF717 PF05338.7 KFP06298.1 - 0.35 10.8 8.0 0.56 10.1 0.2 4.2 4 2 0 4 4 4 0 Protein of unknown function (DUF717) UB2H PF14814.1 KFP06298.1 - 0.39 10.4 10.6 26 4.6 0.1 5.2 2 2 4 6 6 6 0 Bifunctional transglycosylase second domain MUG2_C PF08593.5 KFP06298.1 - 0.65 10.2 18.0 3.9 7.7 0.0 6.2 7 0 0 7 7 7 0 Meiotically up-regulated glycoproteins C-terminal LRR_3 PF07725.7 KFP06298.1 - 3.5 7.5 5.5 74 3.4 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Mab-21 PF03281.9 KFP06299.1 - 5.3e-20 71.7 0.0 7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein PP2C PF00481.16 KFP06300.1 - 3.8e-63 213.2 0.2 4.6e-63 212.9 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFP06300.1 - 2.7e-06 26.9 0.0 4.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C C1q PF00386.16 KFP06301.1 - 0.00073 19.5 0.1 0.0016 18.4 0.0 1.7 1 1 0 1 1 1 1 C1q domain BACK PF07707.10 KFP06302.1 - 1.9e-28 98.2 0.1 4.3e-28 97.1 0.0 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFP06302.1 - 6.4e-27 93.7 0.0 1.1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.20 KFP06302.1 - 4.4e-26 90.1 20.0 1.2e-08 34.3 0.1 7.7 6 2 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFP06302.1 - 6.7e-26 89.3 14.0 1.5e-06 28.1 0.0 6.7 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFP06302.1 - 7.4e-13 47.7 6.6 0.28 11.0 0.0 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.1 KFP06302.1 - 1.2e-10 40.9 10.2 0.0017 18.0 0.0 6.6 5 2 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP06302.1 - 1e-09 38.1 1.3 0.0091 15.9 0.0 4.2 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 KFP06302.1 - 2.2e-09 37.2 8.5 3e-05 24.0 0.4 5.6 4 2 1 5 5 5 2 Galactose oxidase, central domain Git3 PF11710.3 KFP06302.1 - 0.15 11.6 0.4 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 ETS_PEA3_N PF04621.8 KFP06303.1 - 4.9e-134 446.8 12.4 6.4e-134 446.5 8.6 1.1 1 0 0 1 1 1 1 PEA3 subfamily ETS-domain transcription factor N terminal domain Ets PF00178.17 KFP06303.1 - 1.4e-35 121.2 0.1 2.2e-35 120.6 0.1 1.3 1 0 0 1 1 1 1 Ets-domain DAGK_acc PF00609.14 KFP06304.1 - 8.9e-56 188.4 0.0 1.4e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAG_kinase_N PF14513.1 KFP06304.1 - 5.1e-47 159.5 0.0 1e-46 158.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus DAGK_cat PF00781.19 KFP06304.1 - 7.8e-31 106.2 0.0 1.3e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KFP06304.1 - 1.6e-23 82.1 26.0 3.5e-12 45.8 6.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.27 KFP06304.1 - 3e-10 38.6 2.3 0.00047 19.2 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFP06304.1 - 5.2e-09 36.1 0.6 1.3e-08 34.8 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP06304.1 - 4.2e-08 32.4 0.6 0.0013 18.4 0.1 3.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KFP06304.1 - 3.5e-06 26.1 1.4 0.011 15.0 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFP06304.1 - 7.5e-06 25.4 1.2 0.089 12.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP06304.1 - 0.00013 21.9 0.1 0.00041 20.3 0.0 1.9 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region C1_3 PF07649.7 KFP06304.1 - 1.7 8.7 21.0 0.45 10.5 1.6 3.0 3 0 0 3 3 3 0 C1-like domain IncA PF04156.9 KFP06305.1 - 9.3e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 IncA protein Rhabdo_glycop PF00974.13 KFP06305.1 - 0.0051 15.1 0.3 0.0058 14.9 0.2 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Corona_S2 PF01601.11 KFP06305.1 - 0.007 14.5 2.2 0.011 13.8 1.6 1.3 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Shisa PF13908.1 KFP06305.1 - 0.016 15.3 5.4 0.019 15.1 3.7 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.6 KFP06305.1 - 0.04 13.6 0.9 0.076 12.7 0.6 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF1191 PF06697.7 KFP06305.1 - 0.048 12.4 1.1 0.074 11.8 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) FAM176 PF14851.1 KFP06305.1 - 0.057 13.0 1.0 0.081 12.6 0.7 1.1 1 0 0 1 1 1 0 FAM176 family TMEM154 PF15102.1 KFP06305.1 - 0.062 13.0 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 KFP06305.1 - 0.062 13.6 0.6 0.12 12.7 0.4 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CCER1 PF15482.1 KFP06305.1 - 0.25 10.9 8.0 0.31 10.6 5.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Rad60-SLD PF11976.3 KFP06306.1 - 8.8e-22 76.5 0.6 7.8e-11 41.5 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFP06306.1 - 1e-07 31.2 0.1 6.1e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family DUF2777 PF10949.3 KFP06306.1 - 0.072 12.7 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) DUF3581 PF12119.3 KFP06306.1 - 0.11 11.6 0.0 0.14 11.4 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3581) UQ_con PF00179.21 KFP06307.1 - 3.2e-47 159.4 0.0 3.5e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EPTP PF03736.12 KFP06308.1 - 3.9e-59 196.1 12.5 1e-13 50.7 0.1 7.6 7 0 0 7 7 7 7 EPTP domain Laminin_G_2 PF02210.19 KFP06308.1 - 1.5e-06 28.2 0.0 3.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.1 KFP06308.1 - 1.9e-06 28.2 0.0 5.8e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_1 PF00054.18 KFP06308.1 - 0.0029 17.6 0.0 0.0079 16.2 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain LRR_8 PF13855.1 KFP06309.1 - 2.6e-16 59.1 0.5 6.8e-13 48.1 0.0 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KFP06309.1 - 1.3e-10 39.7 0.2 0.0014 18.4 0.1 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.2 KFP06309.1 - 2.4e-10 39.7 0.1 0.00022 20.7 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT PF01462.13 KFP06309.1 - 4.5e-07 29.1 2.8 8.3e-07 28.3 2.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFP06309.1 - 8.7e-07 28.1 0.3 0.032 14.3 0.0 3.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFP06309.1 - 2.5e-05 23.8 0.0 0.29 11.3 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeat LRR_5 PF13306.1 KFP06309.1 - 0.0094 15.6 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LSR PF05624.9 KFP06309.1 - 2.4 7.9 10.4 0.94 9.2 4.1 2.2 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Ion_trans PF00520.26 KFP06310.1 - 1.8e-13 50.2 12.0 1.8e-13 50.2 8.3 2.0 2 0 0 2 2 2 1 Ion transport protein DUF1794 PF08768.6 KFP06311.1 - 5.4e-51 172.4 0.0 8.4e-51 171.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) THAP PF05485.7 KFP06311.1 - 2e-14 53.5 0.5 5.7e-14 52.0 0.3 1.8 1 0 0 1 1 1 1 THAP domain DUF4201 PF13870.1 KFP06311.1 - 0.0091 15.4 0.9 0.019 14.4 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) HrpB7 PF09486.5 KFP06311.1 - 0.011 15.6 0.5 0.094 12.6 0.2 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DivIC PF04977.10 KFP06311.1 - 0.19 11.2 1.7 0.47 9.9 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator Peptidase_C54 PF03416.14 KFP06312.1 - 8.3e-107 356.4 0.0 1.1e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 PI3K_p85B PF02192.11 KFP06312.1 - 0.081 12.3 0.0 0.28 10.6 0.0 1.9 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain PH PF00169.24 KFP06312.1 - 0.088 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 PH domain Thymidylate_kin PF02223.12 KFP06313.1 - 1.9e-36 125.2 0.0 2.2e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase ING PF12998.2 KFP06314.1 - 1e-16 61.0 1.9 1.4e-16 60.6 1.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFP06314.1 - 4.1e-10 39.1 8.3 7.9e-10 38.2 5.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 KFP06314.1 - 0.014 15.4 5.3 0.024 14.6 3.7 1.4 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.1 KFP06314.1 - 0.03 14.4 1.4 0.048 13.8 0.3 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain HD_3 PF13023.1 KFP06314.1 - 0.071 12.8 0.7 0.097 12.4 0.5 1.2 1 0 0 1 1 1 0 HD domain RRF PF01765.14 KFP06314.1 - 0.12 11.8 3.2 0.16 11.4 2.2 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Gal-3-0_sulfotr PF06990.6 KFP06315.1 - 1.7e-133 445.1 4.9 1.9e-133 445.0 3.4 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 KFP06315.1 - 0.0002 21.1 0.1 0.00039 20.1 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family BNR_2 PF13088.1 KFP06316.1 - 2.4e-30 105.7 0.0 3e-26 92.3 0.0 2.1 2 0 0 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.1 KFP06316.1 - 8.4e-06 25.0 0.0 1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KFP06316.1 - 0.0013 18.2 3.6 0.84 9.7 0.1 3.9 3 0 0 3 3 3 2 BNR/Asp-box repeat L6_membrane PF05805.7 KFP06317.1 - 4.2e-49 166.7 8.9 4.8e-49 166.5 6.1 1.0 1 0 0 1 1 1 1 L6 membrane protein UBX PF00789.15 KFP06318.1 - 4.3e-18 65.1 0.0 7.9e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 KFP06318.1 - 1.1e-12 47.7 0.1 2.2e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KFP06318.1 - 4.9e-09 35.5 0.1 1.3e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 UBA-like domain Thioredox_DsbH PF03190.10 KFP06318.1 - 0.02 14.6 0.3 0.035 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 zf-RING_5 PF14634.1 KFP06319.1 - 0.012 15.2 11.1 0.047 13.4 7.7 2.1 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.1 KFP06319.1 - 0.041 13.4 7.8 0.14 11.7 5.4 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 KFP06319.1 - 0.3 10.7 12.4 1.2 8.8 8.6 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP06319.1 - 0.52 10.1 12.7 1.6 8.6 8.8 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KFP06319.1 - 0.8 9.7 12.4 3.1 7.8 8.6 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP06319.1 - 3.5 7.3 17.4 0.08 12.6 6.7 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFP06319.1 - 3.8 7.1 13.0 1.1 8.8 6.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain WD40 PF00400.27 KFP06320.1 - 5e-20 70.5 2.1 0.00018 21.2 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat LRR_8 PF13855.1 KFP06321.1 - 7.1e-48 160.2 57.9 1.1e-09 37.8 0.2 9.2 5 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFP06321.1 - 1.3e-32 110.8 58.7 0.00021 20.8 1.6 12.8 6 4 6 14 14 14 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP06321.1 - 2.6e-20 69.3 59.3 0.13 12.3 0.1 19.2 18 2 1 19 19 19 7 Leucine Rich Repeat LRR_6 PF13516.1 KFP06321.1 - 2.1e-08 33.3 61.4 0.56 10.4 0.1 17.0 16 2 3 19 19 19 4 Leucine Rich repeat LRR_7 PF13504.1 KFP06321.1 - 1.2e-05 24.7 65.0 8.6 7.0 0.1 17.0 18 1 0 18 18 18 5 Leucine rich repeat LRR_5 PF13306.1 KFP06321.1 - 0.0016 18.1 0.1 0.13 11.9 0.0 3.5 3 1 1 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFP06321.1 - 0.16 11.5 10.6 3.8 7.0 0.0 4.7 1 1 1 4 4 4 0 Leucine-rich repeat CEP19 PF14933.1 KFP06322.1 - 4.3e-34 118.0 3.1 4.8e-34 117.9 2.1 1.0 1 0 0 1 1 1 1 CEP19-like protein PIG-X PF08320.7 KFP06323.1 - 2.1e-35 121.9 0.0 2.4e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 Pkinase PF00069.20 KFP06324.1 - 5e-73 245.4 0.0 7.6e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06324.1 - 1.1e-47 162.3 0.0 1.7e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFP06324.1 - 7.3e-24 83.9 0.0 2e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KFP06324.1 - 4.7e-09 35.6 0.0 0.00014 20.9 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 KFP06324.1 - 0.00078 19.2 0.0 0.0092 15.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP06324.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIP PF00230.15 KFP06325.1 - 6e-10 38.9 7.0 9.5e-10 38.3 4.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein Gal-3-0_sulfotr PF06990.6 KFP06326.1 - 2.6e-121 405.0 0.1 2.9e-121 404.9 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 KFP06326.1 - 2.8e-06 27.1 0.0 8e-05 22.4 0.0 2.5 1 1 0 1 1 1 1 Sulfotransferase family RhoGEF PF00621.15 KFP06327.1 - 3.8e-49 167.0 7.5 3.8e-49 167.0 5.2 1.6 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KFP06327.1 - 3.1e-12 45.8 0.2 5.8e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFP06327.1 - 8.1e-10 38.8 0.8 1.7e-09 37.8 0.5 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 KFP06327.1 - 8.8e-10 37.8 2.0 1.7e-09 36.9 1.4 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP06327.1 - 5.3e-08 32.2 0.0 9.9e-08 31.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain 7tm_1 PF00001.16 KFP06328.1 - 3.9e-08 32.7 28.6 7.7e-08 31.7 19.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Kelch_1 PF01344.20 KFP06329.1 - 1.5e-43 146.0 0.1 8.4e-12 44.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFP06329.1 - 2.3e-33 112.9 0.1 2.2e-06 27.5 0.0 5.8 2 1 4 6 6 6 5 Kelch motif BACK PF07707.10 KFP06329.1 - 5.6e-31 106.4 0.2 1.3e-30 105.2 0.2 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 KFP06329.1 - 3.4e-27 94.6 4.6 4.9e-27 94.1 1.7 2.2 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 KFP06329.1 - 2e-24 84.3 0.3 0.00014 21.5 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 KFP06329.1 - 9.5e-17 60.5 0.0 0.029 14.1 0.0 6.0 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KFP06329.1 - 2.4e-16 59.4 0.1 0.012 15.7 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP06329.1 - 3.9e-12 45.8 0.9 0.00086 19.2 0.0 5.9 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.3 KFP06329.1 - 0.0001 21.5 2.1 0.00015 20.9 0.5 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_1 PF01344.20 KFP06330.1 - 5.5e-53 176.2 20.7 1.1e-13 50.4 0.0 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFP06330.1 - 3.3e-37 125.1 9.2 6.1e-07 29.3 0.0 6.5 3 1 3 6 6 6 6 Kelch motif BACK PF07707.10 KFP06330.1 - 3.7e-32 110.2 0.5 3.7e-32 110.2 0.3 1.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFP06330.1 - 6.5e-29 100.1 1.5 1.5e-28 98.9 0.6 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFP06330.1 - 2.6e-28 97.5 5.2 5.9e-05 23.1 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP06330.1 - 1.4e-24 85.6 7.2 3.1e-05 23.6 0.0 6.9 6 2 1 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP06330.1 - 3.1e-21 74.2 11.7 1.1e-05 24.9 0.1 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFP06330.1 - 9.8e-10 38.1 9.7 0.092 12.7 0.1 6.0 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 KFP06330.1 - 0.0024 17.0 0.8 0.0045 16.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) YEATS PF03366.11 KFP06331.1 - 7.3e-25 86.5 0.9 7.3e-25 86.5 0.6 2.3 2 0 0 2 2 2 1 YEATS family Aminotran_1_2 PF00155.16 KFP06332.1 - 9.7e-59 199.1 0.0 1.1e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFP06332.1 - 1.1e-05 24.7 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFP06332.1 - 0.0045 15.7 0.0 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V AMOP PF03782.12 KFP06333.1 - 4.8e-41 140.2 4.7 4.8e-41 140.2 3.2 2.2 2 0 0 2 2 2 1 AMOP domain TSP_1 PF00090.14 KFP06333.1 - 5e-07 29.7 12.4 5e-07 29.7 8.6 2.4 2 0 0 2 2 2 1 Thrombospondin type 1 domain Asparaginase_2 PF01112.13 KFP06334.1 - 1.6e-41 142.1 0.1 2.5e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Asparaginase Methyltransf_11 PF08241.7 KFP06335.1 - 1.4e-21 76.8 0.0 2.1e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP06335.1 - 7e-15 55.1 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP06335.1 - 2.6e-13 49.8 0.0 3.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP06335.1 - 5.5e-11 42.7 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP06335.1 - 1.2e-10 41.7 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFP06335.1 - 5.5e-10 38.7 0.0 8.9e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 KFP06335.1 - 1.5e-06 26.8 0.0 2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 KFP06335.1 - 0.0002 21.9 0.0 0.00047 20.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP06335.1 - 0.001 18.4 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFP06335.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFP06335.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.7 KFP06335.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.6 KFP06335.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Macro PF01661.16 KFP06336.1 - 1.5e-43 147.4 0.5 2.6e-43 146.6 0.3 1.4 1 0 0 1 1 1 1 Macro domain LRR_8 PF13855.1 KFP06337.1 - 1.6e-30 104.5 31.7 5.5e-12 45.2 1.8 5.3 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 KFP06337.1 - 2.6e-21 74.7 41.9 3e-08 33.0 1.2 7.2 2 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP06337.1 - 2.1e-13 48.3 34.1 0.069 13.2 0.2 11.4 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_5 PF13306.1 KFP06337.1 - 3e-08 33.4 0.3 0.00012 21.8 0.0 3.8 1 1 3 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFP06337.1 - 1.8e-06 27.5 9.2 0.0077 15.8 1.7 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 KFP06337.1 - 0.00053 19.7 34.1 6.2 7.4 0.1 10.9 12 0 0 12 12 12 1 Leucine rich repeat LRRNT PF01462.13 KFP06337.1 - 0.00057 19.2 3.3 0.0017 17.7 1.4 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain fn3 PF00041.16 KFP06337.1 - 0.004 17.2 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.19 KFP06337.1 - 0.023 14.9 0.0 0.073 13.3 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Herpes_gE PF02480.11 KFP06337.1 - 0.049 11.8 0.0 0.069 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kinesin PF00225.18 KFP06338.1 - 1.2e-111 372.6 0.7 1.2e-111 372.6 0.5 4.0 3 1 1 5 5 5 1 Kinesin motor domain PX PF00787.19 KFP06338.1 - 3.3e-16 59.0 0.6 3.3e-16 59.0 0.4 3.6 3 1 0 3 3 3 1 PX domain RecO_N_2 PF13114.1 KFP06338.1 - 0.021 14.5 0.0 0.096 12.4 0.0 2.1 1 0 0 1 1 1 0 RecO N terminal PLAC9 PF15205.1 KFP06338.1 - 0.91 9.8 4.9 4.3 7.6 0.2 3.5 3 1 0 3 3 3 0 Placenta-specific protein 9 RRM_1 PF00076.17 KFP06339.1 - 8.1e-27 92.6 0.5 1.5e-14 53.3 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06339.1 - 1.2e-17 63.4 0.5 2.2e-11 43.3 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP06339.1 - 9.4e-15 54.3 0.4 8.2e-07 28.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KFP06339.1 - 4.2e-05 23.2 0.6 0.0009 18.8 0.0 2.5 2 1 0 2 2 2 1 Calcipressin DUF45 PF01863.12 KFP06339.1 - 0.044 13.5 0.6 0.11 12.3 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF45 SH3_2 PF07653.12 KFP06340.1 - 2.8e-18 65.1 0.0 4.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KFP06340.1 - 2.7e-05 23.6 0.1 5.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF239 PF03080.10 KFP06340.1 - 0.018 14.1 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF239) Peptidase_S8 PF00082.17 KFP06342.1 - 2.3e-53 181.2 3.6 3.3e-53 180.6 2.5 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFP06342.1 - 4.7e-30 103.2 0.1 9.5e-30 102.2 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Filament PF00038.16 KFP06343.1 - 1.3e-22 80.6 44.1 4.1e-22 79.0 14.1 2.8 4 0 0 4 4 4 2 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFP06343.1 - 0.0082 15.8 38.9 0.017 14.8 8.4 5.3 4 2 0 4 4 4 2 TPR/MLP1/MLP2-like protein Lectin_N PF03954.9 KFP06343.1 - 0.22 10.9 4.3 0.24 10.7 0.5 2.7 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 KFP06343.1 - 1.7 8.4 14.3 0.19 11.5 0.7 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.4 KFP06343.1 - 6.5 6.4 6.9 2 8.0 0.7 3.1 4 1 0 4 4 4 0 Apolipoprotein O 7tm_1 PF00001.16 KFP06344.1 - 2.7e-48 164.3 23.8 3.5e-48 163.9 16.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06344.1 - 1.5e-05 24.2 27.0 2.1e-05 23.8 18.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFP06345.1 - 7.7e-13 48.4 4.3 8.6e-13 48.3 3.0 1.0 1 0 0 1 1 1 1 Olfactory receptor EF-hand_4 PF12763.2 KFP06346.1 - 2e-42 143.1 0.0 9.9e-23 79.8 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFP06346.1 - 2.3e-12 45.2 2.3 0.002 17.3 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KFP06346.1 - 9.7e-11 41.6 0.5 7.8e-05 22.7 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP06346.1 - 6.1e-09 35.0 1.1 0.12 12.3 0.1 5.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 KFP06346.1 - 0.00015 21.3 2.5 0.046 13.3 0.1 4.0 3 1 1 4 4 4 1 EF-hand domain pair Macoilin PF09726.4 KFP06346.1 - 0.00064 18.1 26.2 0.0011 17.3 18.1 1.2 1 0 0 1 1 1 1 Transmembrane protein EzrA PF06160.7 KFP06346.1 - 0.00083 17.6 30.8 0.0047 15.1 22.3 1.5 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA IFT57 PF10498.4 KFP06346.1 - 0.00089 18.0 27.9 0.002 16.9 19.3 1.5 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 EF-hand_5 PF13202.1 KFP06346.1 - 0.0011 18.1 2.4 0.34 10.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 KFP06346.1 - 0.0031 17.3 0.6 0.79 9.6 0.0 3.6 4 0 0 4 4 3 1 EF-hand domain Reo_sigmaC PF04582.7 KFP06346.1 - 0.0044 16.2 16.9 0.16 11.1 4.3 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Spc7 PF08317.6 KFP06346.1 - 0.0072 15.0 42.2 0.046 12.3 13.9 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein Prominin PF05478.6 KFP06346.1 - 0.012 13.1 20.9 0.016 12.7 14.5 1.1 1 0 0 1 1 1 0 Prominin IncA PF04156.9 KFP06346.1 - 0.023 14.2 59.2 0.037 13.6 20.5 2.8 2 1 1 3 3 3 0 IncA protein MAD PF05557.8 KFP06346.1 - 0.065 11.3 35.7 0.1 10.6 24.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4201 PF13870.1 KFP06346.1 - 0.14 11.5 36.3 0.018 14.5 13.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) AAA_13 PF13166.1 KFP06346.1 - 0.15 10.4 34.2 0.68 8.3 23.8 1.8 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.6 KFP06346.1 - 0.46 10.3 22.2 0.17 11.7 3.2 3.4 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CALCOCO1 PF07888.6 KFP06346.1 - 0.98 7.6 34.1 1.5 7.0 23.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MCPsignal PF00015.16 KFP06346.1 - 2.1 7.8 20.1 0.023 14.2 2.8 2.5 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Atg14 PF10186.4 KFP06346.1 - 2.2 7.1 40.3 3.2 6.6 9.1 2.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 KFP06346.1 - 7.5 6.3 31.7 5.1 6.8 0.8 3.2 1 1 2 3 3 3 0 Laminin Domain II FUSC PF04632.7 KFP06346.1 - 8.7 4.6 6.4 14 3.9 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spectrin PF00435.16 KFP06346.1 - 9.7 6.5 35.9 4.2 7.6 10.5 2.9 1 1 1 2 2 2 0 Spectrin repeat zf-C2H2 PF00096.21 KFP06347.1 - 2e-15 56.0 23.7 2.2e-05 24.5 3.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP06347.1 - 9.3e-12 44.4 19.8 0.00098 19.2 1.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP06347.1 - 1.1e-10 41.1 12.7 5.5e-07 29.5 3.1 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP06347.1 - 0.04 14.0 6.0 3.1 8.0 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP06347.1 - 0.14 12.3 10.1 1.6 9.0 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Adap_comp_sub PF00928.16 KFP06348.1 - 8.4e-87 290.5 0.5 4.4e-79 265.2 0.1 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFP06348.1 - 3.5e-05 23.5 0.8 5.7e-05 22.8 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SH3_5 PF08460.5 KFP06348.1 - 0.098 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain DUF1754 PF08555.5 KFP06349.1 - 5.1e-08 33.4 19.1 4.3e-05 24.0 6.1 2.6 2 1 1 3 3 3 2 Eukaryotic family of unknown function (DUF1754) UPF0172 PF03665.8 KFP06349.1 - 0.0057 16.1 1.8 0.007 15.8 1.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF4407 PF14362.1 KFP06349.1 - 0.074 11.9 3.8 0.086 11.7 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L17 PF01196.14 KFP06349.1 - 0.24 12.0 4.5 0.31 11.6 3.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L17 Wx5_PLAF3D7 PF09688.5 KFP06349.1 - 0.25 11.3 3.6 0.28 11.1 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) Phlebovirus_NSM PF07246.6 KFP06349.1 - 0.25 10.4 5.2 0.31 10.1 3.6 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Sec62 PF03839.11 KFP06349.1 - 0.69 9.2 9.2 0.76 9.1 6.4 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 EF-hand_7 PF13499.1 KFP06350.1 - 8.4e-14 51.4 4.1 5.4e-12 45.6 0.8 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP06350.1 - 7.2e-12 43.6 4.2 1.5e-05 23.9 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFP06350.1 - 6.6e-10 38.0 4.3 0.0045 16.7 0.2 3.8 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KFP06350.1 - 8.2e-07 28.5 4.0 0.00024 20.6 0.2 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP06350.1 - 3.4e-06 26.1 0.8 0.00089 18.4 0.1 3.0 3 0 0 3 3 3 2 EF hand AF0941-like PF14591.1 KFP06350.1 - 0.0027 17.7 0.0 0.011 15.8 0.0 1.9 2 1 0 2 2 2 1 AF0941-like SPARC_Ca_bdg PF10591.4 KFP06350.1 - 0.08 12.9 0.7 0.19 11.7 0.4 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Ras PF00071.17 KFP06351.1 - 7e-45 152.3 0.1 8.4e-45 152.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06351.1 - 1.2e-10 41.9 0.0 2.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06351.1 - 6.8e-06 25.4 0.2 8e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family BsuPI PF12690.2 KFP06351.1 - 0.045 13.4 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Intracellular proteinase inhibitor DUF3963 PF13124.1 KFP06351.1 - 0.059 13.1 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Gtr1_RagA PF04670.7 KFP06351.1 - 0.1 11.7 0.0 0.3 10.2 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Tropomyosin PF00261.15 KFP06352.1 - 1.9e-105 351.1 85.8 2.9e-99 330.9 42.9 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.2 KFP06352.1 - 4.5e-41 140.0 73.7 5.4e-37 126.8 27.9 3.1 2 1 0 2 2 2 2 Tropomyosin like Laminin_II PF06009.7 KFP06352.1 - 9.3e-08 31.9 31.7 0.00023 20.9 4.7 3.3 1 1 2 3 3 3 2 Laminin Domain II MscS_porin PF12795.2 KFP06352.1 - 9.8e-05 21.7 38.6 0.025 13.9 12.3 2.7 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain Laminin_I PF06008.9 KFP06352.1 - 0.00016 21.0 49.0 0.0009 18.6 8.7 3.1 1 1 2 3 3 3 2 Laminin Domain I TMF_DNA_bd PF12329.3 KFP06352.1 - 0.00057 19.6 14.9 0.00057 19.6 10.3 6.0 1 1 5 6 6 5 3 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KFP06352.1 - 0.0006 19.4 56.8 0.001 18.6 14.9 3.0 1 1 1 2 2 1 1 IncA protein Reo_sigmaC PF04582.7 KFP06352.1 - 0.002 17.3 7.0 0.025 13.7 0.6 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFP06352.1 - 0.0047 15.4 49.6 0.066 11.6 19.9 2.0 1 1 1 2 2 2 2 AAA domain CENP-F_leu_zip PF10473.4 KFP06352.1 - 0.0063 16.3 66.2 0.021 14.6 21.7 2.5 2 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 KFP06352.1 - 0.013 15.3 52.7 0.014 15.1 7.2 3.7 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) WEMBL PF05701.6 KFP06352.1 - 0.025 13.0 70.3 0.008 14.6 12.7 3.8 1 1 3 4 4 4 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 KFP06352.1 - 0.026 12.2 67.7 2.4 5.7 46.9 2.5 1 1 0 1 1 1 0 Myosin tail Flagellin_N PF00669.15 KFP06352.1 - 0.074 12.8 13.8 0.58 9.9 2.8 3.6 1 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF869 PF05911.6 KFP06352.1 - 0.099 10.8 52.9 1.5 6.9 19.4 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) RmuC PF02646.11 KFP06352.1 - 0.15 10.9 28.1 0.096 11.5 1.2 3.9 1 1 3 4 4 4 0 RmuC family DUF4200 PF13863.1 KFP06352.1 - 0.29 11.0 67.9 0.51 10.2 18.0 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) SlyX PF04102.7 KFP06352.1 - 0.36 11.2 38.1 0.15 12.4 0.6 5.8 2 2 2 5 5 5 0 SlyX NPV_P10 PF05531.7 KFP06352.1 - 0.39 10.9 19.3 2.6 8.3 1.6 4.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KFP06352.1 - 0.6 10.2 31.9 0.85 9.7 4.6 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family EzrA PF06160.7 KFP06352.1 - 0.75 7.8 50.0 5.7 4.9 7.3 3.4 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA ADIP PF11559.3 KFP06352.1 - 0.96 9.3 49.1 1.1 9.1 4.6 4.0 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding FH2 PF02181.18 KFP06352.1 - 1.3 7.7 38.4 0.11 11.3 5.9 3.2 1 1 2 3 3 3 0 Formin Homology 2 Domain APG6 PF04111.7 KFP06352.1 - 1.4 7.9 60.7 3.6 6.5 15.5 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF3584 PF12128.3 KFP06352.1 - 1.9 5.6 54.1 0.8 6.9 16.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) LOH1CR12 PF10158.4 KFP06352.1 - 2.3 7.9 15.2 0.31 10.8 1.0 3.5 2 2 2 4 4 4 0 Tumour suppressor protein Nup54 PF13874.1 KFP06352.1 - 3.2 7.4 34.4 2.3 7.9 1.0 4.1 1 1 4 5 5 5 0 Nucleoporin complex subunit 54 GAS PF13851.1 KFP06352.1 - 4.5 6.4 61.7 6.1 5.9 11.6 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Flagellin_C PF00700.16 KFP06352.1 - 6.4 7.0 14.7 4.5 7.5 0.2 4.4 2 2 2 4 4 4 0 Bacterial flagellin C-terminal helical region Uds1 PF15456.1 KFP06352.1 - 8.1 6.4 49.4 4.6 7.2 4.8 5.4 1 1 4 5 5 5 0 Up-regulated During Septation GTPase_Cys_C PF12631.2 KFP06352.1 - 8.5 6.8 21.4 0.22 11.9 3.2 4.5 1 1 2 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE V_ATPase_I PF01496.14 KFP06352.1 - 8.8 4.0 36.8 34 2.0 25.5 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TGF_beta PF00019.15 KFP06353.1 - 6.3e-34 116.4 0.1 6.3e-34 116.4 0.1 1.6 2 0 0 2 2 2 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP06353.1 - 6.4e-30 104.2 0.0 4.9e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 TGF-beta propeptide CI-B14_5a PF07347.7 KFP06354.1 - 1.2e-27 95.5 0.7 1.4e-27 95.2 0.5 1.3 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ribosomal_S28e PF01200.13 KFP06355.1 - 9.8e-30 102.1 1.9 1.1e-29 102.0 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ank_2 PF12796.2 KFP06356.1 - 5.1e-32 110.0 13.9 2.2e-18 66.3 0.6 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP06356.1 - 2e-29 101.3 10.3 7.1e-12 45.4 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KFP06356.1 - 3.5e-29 99.1 11.7 3.6e-10 39.1 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFP06356.1 - 6.2e-25 86.6 9.9 1.1e-11 44.5 0.2 4.3 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP06356.1 - 7e-21 72.2 7.4 2.9e-06 26.9 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 KFP06357.1 - 3.6e-61 203.5 5.2 4.7e-19 68.5 0.1 4.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFP06357.1 - 1.8e-53 175.7 11.0 3.9e-08 32.7 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KFP06357.1 - 8.5e-37 124.8 8.5 1.5e-10 41.3 0.1 5.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP06357.1 - 1.4e-36 123.6 9.7 6.9e-10 38.8 0.1 6.9 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP06357.1 - 1.9e-35 117.3 1.5 4.3e-06 26.4 0.0 8.0 7 1 0 7 7 7 7 Ankyrin repeat TPR_12 PF13424.1 KFP06357.1 - 0.0018 18.1 0.1 0.073 13.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFP06357.1 - 0.02 14.7 3.5 0.14 12.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP06357.1 - 0.024 14.5 0.2 0.51 10.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TIR_2 PF13676.1 KFP06358.1 - 0.00016 21.7 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.15 KFP06358.1 - 0.014 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 TIR domain DUF2007 PF09413.5 KFP06358.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) Perilipin PF03036.11 KFP06359.1 - 2e-112 375.8 13.0 2.3e-112 375.6 9.0 1.0 1 0 0 1 1 1 1 Perilipin family UPF0444 PF15475.1 KFP06359.1 - 0.033 14.2 7.4 0.051 13.6 2.7 2.3 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 DUF2452 PF10504.4 KFP06359.1 - 0.14 11.3 4.5 3.8 6.7 0.0 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2452) COG5 PF10392.4 KFP06359.1 - 1.2 9.0 7.1 0.85 9.5 0.1 3.3 3 1 1 4 4 4 0 Golgi transport complex subunit 5 SAD_SRA PF02182.12 KFP06360.1 - 9e-56 187.4 0.1 2e-55 186.3 0.1 1.6 1 0 0 1 1 1 1 SAD/SRA domain DUF3590 PF12148.3 KFP06360.1 - 1.4e-41 139.9 0.4 2.9e-41 138.9 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3590) PHD PF00628.24 KFP06360.1 - 1.4e-12 47.0 7.7 1.4e-12 47.0 5.3 3.5 3 1 0 3 3 3 1 PHD-finger zf-C3HC4_2 PF13923.1 KFP06360.1 - 0.00058 19.8 13.4 0.00058 19.8 9.3 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP06360.1 - 0.00059 19.4 13.2 0.00059 19.4 9.2 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 KFP06360.1 - 0.00063 18.9 0.8 0.00063 18.9 0.5 2.9 4 0 0 4 4 4 1 PHD-finger zf-RING_2 PF13639.1 KFP06360.1 - 0.0037 17.0 12.5 0.0037 17.0 8.6 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KFP06360.1 - 0.013 15.2 11.9 0.013 15.2 8.3 3.5 2 1 0 2 2 2 0 zinc-RING finger domain Tudor-knot PF11717.3 KFP06360.1 - 0.023 14.4 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain JmjC PF02373.17 KFP06361.1 - 5e-44 149.1 0.0 1.3e-43 147.9 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KFP06361.1 - 3.2e-36 123.6 8.8 3.2e-36 123.6 6.1 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFP06361.1 - 5.6e-18 64.8 5.4 5.6e-18 64.8 3.7 3.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 KFP06361.1 - 8.5e-14 50.7 0.0 2.1e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.1 KFP06361.1 - 2.3e-13 49.1 6.6 2.3e-13 49.1 4.6 2.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KFP06361.1 - 1.1e-06 28.2 22.2 4.4e-05 23.0 1.8 3.6 3 0 0 3 3 3 2 PHD-finger LBR_tudor PF09465.5 KFP06361.1 - 0.0014 18.1 0.8 0.22 11.2 0.0 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain Rad9_Rad53_bind PF08605.5 KFP06361.1 - 0.039 13.7 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding DUF4537 PF15057.1 KFP06361.1 - 0.04 13.7 0.1 0.45 10.3 0.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.5 KFP06361.1 - 0.2 11.5 0.2 1.7 8.4 0.2 2.2 1 1 1 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor Tmemb_161AB PF10268.4 KFP06365.1 - 7.5e-170 565.6 6.9 8.3e-170 565.4 4.8 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Mito_carr PF00153.22 KFP06366.1 - 7.4e-73 240.3 1.7 2.2e-26 91.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Arm PF00514.18 KFP06367.1 - 2.5e-11 42.9 5.9 0.059 13.2 0.0 5.9 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 KFP06367.1 - 0.00069 19.3 2.6 0.59 9.9 0.1 4.3 3 1 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.3 KFP06367.1 - 0.04 13.5 0.2 0.25 10.9 0.0 2.4 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Surp PF01805.15 KFP06368.1 - 3.8e-19 68.0 0.1 2.2e-11 43.2 0.0 2.7 2 0 0 2 2 2 2 Surp module G-patch PF01585.18 KFP06368.1 - 2.2e-14 52.9 4.2 4.6e-14 51.9 2.9 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFP06368.1 - 0.0033 17.2 2.6 0.0033 17.2 1.8 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site Nop14 PF04147.7 KFP06368.1 - 0.33 8.8 13.1 0.63 7.8 9.1 1.4 1 0 0 1 1 1 0 Nop14-like family Sema PF01403.14 KFP06369.1 - 1.3e-127 425.9 0.0 2.1e-127 425.2 0.0 1.3 1 1 1 2 2 2 1 Sema domain PSI PF01437.20 KFP06369.1 - 2.5e-05 24.3 7.1 2.5e-05 24.3 4.9 2.0 2 0 0 2 2 2 1 Plexin repeat WH1 PF00568.18 KFP06370.1 - 7.5e-37 125.4 0.3 1.4e-36 124.5 0.2 1.5 1 0 0 1 1 1 1 WH1 domain TfoX_N PF04993.8 KFP06370.1 - 0.12 12.1 0.6 0.34 10.7 0.4 1.7 1 0 0 1 1 1 0 TfoX N-terminal domain DUF3461 PF11944.3 KFP06370.1 - 2.1 8.2 9.6 0.085 12.6 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Reo_sigmaC PF04582.7 KFP06370.1 - 2.9 6.9 10.4 4.4 6.4 1.6 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein FtsQ PF03799.10 KFP06370.1 - 4.6 7.4 7.5 9.2 6.4 2.0 2.8 1 1 1 2 2 2 0 Cell division protein FtsQ Phage_GP20 PF06810.6 KFP06370.1 - 6 6.2 23.7 5.1 6.5 7.4 2.7 2 1 0 2 2 2 0 Phage minor structural protein GP20 CorA PF01544.13 KFP06370.1 - 8.3 5.3 10.3 15 4.4 7.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DEAD PF00270.24 KFP06371.1 - 1.1e-28 99.7 1.4 6.1e-28 97.4 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP06371.1 - 4.2e-23 80.9 0.0 8.8e-23 79.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Coatomer_E PF04733.9 KFP06372.1 - 1.4e-113 378.9 3.8 1.5e-113 378.7 2.6 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KFP06372.1 - 1.6e-10 41.1 4.9 9.9e-05 22.6 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP06372.1 - 3.2e-09 36.5 8.8 0.0002 21.6 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFP06372.1 - 6.5e-08 32.1 0.4 1.8e-05 24.2 0.0 2.8 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 KFP06372.1 - 1.7e-07 31.6 0.7 0.00044 20.8 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFP06372.1 - 2.7e-07 29.9 5.6 0.00027 20.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP06372.1 - 5.9e-07 29.5 1.6 0.012 15.7 0.2 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFP06372.1 - 1.9e-06 27.7 0.8 0.0039 17.0 0.0 3.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFP06372.1 - 2.3e-05 23.8 2.2 0.0041 16.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP06372.1 - 0.00011 21.5 5.0 0.0014 18.1 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFP06372.1 - 0.00094 19.0 1.3 0.0092 15.8 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 KFP06372.1 - 0.012 15.4 3.0 4.1 7.6 0.0 3.9 4 0 0 4 4 4 0 PPR repeat TPR_8 PF13181.1 KFP06372.1 - 0.017 14.9 1.2 4.9 7.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 KFP06372.1 - 0.018 14.9 3.8 11 6.1 0.4 3.8 4 0 0 4 4 4 0 PPR repeat family TPR_6 PF13174.1 KFP06372.1 - 0.02 15.3 5.7 1.3 9.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFP06372.1 - 0.034 14.3 0.7 24 5.4 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF964 PF06133.6 KFP06372.1 - 0.065 13.2 2.1 1.9 8.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF964) TPR_4 PF07721.9 KFP06372.1 - 0.089 13.2 0.1 24 5.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFP06372.1 - 2.1 8.2 10.4 4.9 7.0 2.6 3.0 1 1 1 3 3 3 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.11 KFP06373.1 - 2.4e-36 125.1 26.1 2.7e-36 124.9 18.1 1.0 1 0 0 1 1 1 1 TLC domain TGF_beta PF00019.15 KFP06375.1 - 2.4e-42 143.4 0.1 4.2e-42 142.6 0.1 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP06375.1 - 1.8e-11 43.8 4.8 3.1e-11 43.0 2.4 2.1 2 1 0 2 2 2 1 TGF-beta propeptide UPF1_Zn_bind PF09416.5 KFP06376.1 - 1.9e-73 245.1 7.7 5e-73 243.7 5.2 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KFP06376.1 - 3.4e-61 206.1 0.0 6.1e-61 205.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFP06376.1 - 7.6e-52 176.2 0.5 1.3e-51 175.5 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFP06376.1 - 2.8e-14 52.5 0.2 6.9e-14 51.3 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFP06376.1 - 4.4e-12 46.0 0.1 1.4e-10 41.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFP06376.1 - 2.6e-07 30.6 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFP06376.1 - 0.0002 20.4 0.2 0.0041 16.1 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 KFP06376.1 - 0.00043 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Helicase KaiC PF06745.8 KFP06376.1 - 0.00061 18.9 0.0 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 KaiC SRP54 PF00448.17 KFP06376.1 - 0.0047 16.4 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.16 KFP06376.1 - 0.017 14.4 0.1 0.75 9.0 0.0 2.7 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 KFP06376.1 - 0.041 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.9 KFP06376.1 - 0.044 12.7 0.0 4.5 6.1 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_25 PF13481.1 KFP06376.1 - 0.05 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KFP06376.1 - 0.054 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.2 KFP06376.1 - 0.058 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain UvrD_C_2 PF13538.1 KFP06376.1 - 0.077 13.1 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain Ribosomal_S13_N PF08069.7 KFP06376.1 - 0.18 11.6 0.0 0.53 10.1 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA PF00004.24 KFP06376.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TSP_C PF05735.7 KFP06377.1 - 9.8e-107 355.0 1.7 1.4e-106 354.5 1.2 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region TSP_3 PF02412.13 KFP06377.1 - 5.6e-55 182.5 134.2 8.5e-12 44.3 7.8 9.4 7 2 1 8 8 8 8 Thrombospondin type 3 repeat EGF_CA PF07645.10 KFP06377.1 - 1.1e-18 66.9 43.8 3.9e-09 36.3 5.3 5.6 4 0 0 4 4 4 4 Calcium-binding EGF domain COMP PF11598.3 KFP06377.1 - 4e-13 49.1 4.9 4e-13 49.1 3.4 2.0 2 0 0 2 2 2 1 Cartilage oligomeric matrix protein cEGF PF12662.2 KFP06377.1 - 4.2e-11 42.2 26.4 1.2e-05 24.7 2.0 5.8 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.2 KFP06377.1 - 1.4e-07 31.3 51.8 0.00019 21.2 3.8 6.0 6 0 0 6 6 6 4 EGF domain hEGF PF12661.2 KFP06377.1 - 0.0015 18.4 17.0 0.73 10.0 0.6 6.2 4 0 0 4 4 4 2 Human growth factor-like EGF EGF PF00008.22 KFP06377.1 - 0.012 15.6 3.5 0.012 15.6 2.4 5.5 4 0 0 4 4 4 0 EGF-like domain TORC_M PF12885.2 KFP06378.1 - 2.1e-71 238.5 10.0 2.1e-71 238.5 6.9 2.8 3 1 1 4 4 4 1 Transducer of regulated CREB activity middle domain TORC_C PF12886.2 KFP06378.1 - 1.4e-34 118.0 1.8 3.2e-34 116.9 1.3 1.7 1 0 0 1 1 1 1 Transducer of regulated CREB activity, C terminus Kelch_1 PF01344.20 KFP06379.1 - 7e-41 137.5 14.0 9.9e-09 34.6 0.6 6.2 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 KFP06379.1 - 7.5e-35 117.6 2.8 3e-07 30.3 0.0 5.8 3 1 3 6 6 6 5 Kelch motif BACK PF07707.10 KFP06379.1 - 3.6e-25 87.7 0.2 6.9e-25 86.8 0.2 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFP06379.1 - 6.5e-19 67.4 0.6 0.0041 16.8 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP06379.1 - 8.1e-19 66.5 6.4 0.00012 21.6 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 KFP06379.1 - 1.9e-13 50.1 0.1 0.012 15.7 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP06379.1 - 8.3e-13 47.9 6.9 0.16 11.9 0.1 6.0 6 0 0 6 6 6 4 Kelch motif BTB PF00651.26 KFP06379.1 - 9.9e-13 48.0 0.0 1.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PQQ_3 PF13570.1 KFP06379.1 - 0.033 14.4 0.1 4.1 7.7 0.1 3.7 4 0 0 4 4 4 0 PQQ-like domain BSMAP PF12280.3 KFP06380.1 - 2.3e-13 50.5 0.0 2.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF997 PF06196.7 KFP06380.1 - 0.034 13.6 1.1 0.044 13.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) EpoR_lig-bind PF09067.5 KFP06381.1 - 6.1e-14 51.8 0.0 8.8e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding IL6Ra-bind PF09240.5 KFP06381.1 - 1.8e-08 34.4 0.1 4.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding Lep_receptor_Ig PF06328.6 KFP06381.1 - 0.029 14.2 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Ig-like C2-type domain Ig_2 PF13895.1 KFP06381.1 - 0.047 13.8 2.6 1.3 9.1 1.8 2.4 1 1 0 1 1 1 0 Immunoglobulin domain fn3 PF00041.16 KFP06381.1 - 0.048 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain IL4Ra_N PF09238.5 KFP06381.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal ubiquitin PF00240.18 KFP06382.1 - 4.3e-35 118.9 0.3 5.9e-35 118.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 KFP06382.1 - 6.7e-30 102.4 11.8 1.1e-29 101.7 8.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 KFP06382.1 - 5.4e-21 74.0 0.5 5.4e-21 74.0 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFP06382.1 - 3.3e-06 27.2 0.1 1.2e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFP06382.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KFP06382.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFP06382.1 - 0.03 14.5 0.1 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 KFP06382.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Fer2_3 PF13085.1 KFP06382.1 - 0.3 10.9 2.5 0.69 9.7 0.2 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain KxDL PF10241.4 KFP06383.1 - 2.4e-30 104.2 1.1 3.1e-30 103.8 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein TPR_11 PF13414.1 KFP06384.1 - 3.6e-20 71.3 2.6 3.8e-11 42.4 0.7 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFP06384.1 - 1e-16 59.7 3.5 3.1e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP06384.1 - 4.1e-14 51.2 3.1 9e-06 25.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_C PF00254.23 KFP06384.1 - 5e-13 48.8 0.0 1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_16 PF13432.1 KFP06384.1 - 4.6e-11 43.0 1.2 1.9e-08 34.7 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFP06384.1 - 1e-08 34.9 1.5 0.00073 19.3 0.1 2.7 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 KFP06384.1 - 1.2e-08 34.7 3.7 2.8e-06 27.1 0.4 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP06384.1 - 1.3e-08 34.6 0.0 0.00029 21.1 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP06384.1 - 9.1e-08 31.3 3.1 7.3e-05 22.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP06384.1 - 8.6e-07 29.2 0.7 6e-06 26.4 0.1 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP06384.1 - 9e-07 28.6 0.0 8.4e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP06384.1 - 9.1e-07 28.2 0.7 0.0017 17.9 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP06384.1 - 8.9e-05 22.5 0.9 0.0013 18.7 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFP06384.1 - 9.1e-05 22.3 0.3 0.0053 16.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFP06384.1 - 0.00054 19.8 2.4 1.1 9.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.3 KFP06384.1 - 0.00076 18.3 0.4 0.00098 17.9 0.3 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 KFP06384.1 - 0.0013 19.0 0.5 0.1 13.1 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat MIT PF04212.13 KFP06384.1 - 0.0035 17.1 1.6 0.94 9.3 0.1 2.7 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain SPO22 PF08631.5 KFP06384.1 - 0.0068 15.5 2.6 0.072 12.1 0.8 2.2 1 1 1 2 2 2 1 Meiosis protein SPO22/ZIP4 like Alkyl_sulf_dimr PF14863.1 KFP06384.1 - 0.026 14.7 0.1 0.067 13.4 0.0 1.6 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Stk19 PF10494.4 KFP06384.1 - 0.054 12.8 0.5 0.11 11.8 0.4 1.4 1 1 0 1 1 1 0 Serine-threonine protein kinase 19 TPR_20 PF14561.1 KFP06384.1 - 0.056 13.5 0.2 0.26 11.4 0.1 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat ELL PF10390.4 KFP06385.1 - 8.8e-97 323.7 0.0 8.8e-97 323.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.8 KFP06385.1 - 5.7e-37 126.5 12.4 5.7e-37 126.5 8.6 2.9 3 0 0 3 3 3 1 Occludin homology domain Pox_Ag35 PF03286.9 KFP06385.1 - 0.036 13.5 7.9 0.078 12.4 5.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 KFP06385.1 - 0.27 10.8 6.5 0.6 9.7 4.5 1.5 1 0 0 1 1 1 0 FAM176 family Med4 PF10018.4 KFP06385.1 - 0.9 8.9 11.3 0.061 12.7 1.3 2.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 RP-C_C PF11800.3 KFP06385.1 - 2.5 7.7 10.5 1.1 8.8 0.5 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Seryl_tRNA_N PF02403.17 KFP06385.1 - 3.2 7.8 13.7 0.28 11.2 1.3 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NAD_binding_5 PF07994.7 KFP06386.1 - 1.3e-92 310.4 0.0 1.6e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KFP06386.1 - 5.5e-24 84.1 0.5 1.1e-23 83.2 0.3 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Peptidase_C15 PF01470.12 KFP06387.1 - 1.1e-18 67.8 0.0 1.3e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase DUF3060 PF11259.3 KFP06387.1 - 0.0085 15.6 0.4 2.4 7.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3060) LSM PF01423.17 KFP06388.1 - 2.5e-11 42.9 0.0 3.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain bZIP_1 PF00170.16 KFP06389.1 - 3e-19 68.7 17.6 3.4e-19 68.5 12.2 1.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KFP06389.1 - 2.3e-10 40.5 8.5 2.9e-10 40.2 5.9 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KFP06389.1 - 4.5e-09 35.9 16.1 8.5e-09 35.0 11.2 1.5 1 1 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.8 KFP06389.1 - 0.00025 20.1 2.9 0.00028 19.9 2.0 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF904 PF06005.7 KFP06389.1 - 0.0029 17.8 4.8 0.0029 17.8 3.3 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF904) Jun PF03957.8 KFP06389.1 - 0.0044 16.7 1.9 0.0044 16.7 1.3 1.6 2 0 0 2 2 2 1 Jun-like transcription factor PspA_IM30 PF04012.7 KFP06389.1 - 0.0044 16.4 4.4 0.0044 16.4 3.1 1.6 1 1 1 2 2 2 1 PspA/IM30 family DUF3450 PF11932.3 KFP06389.1 - 0.0044 16.3 2.1 0.0053 16.0 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.4 KFP06389.1 - 0.0054 16.7 2.9 0.0069 16.3 2.0 1.0 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 IncA PF04156.9 KFP06389.1 - 0.022 14.3 4.8 0.029 13.9 3.3 1.1 1 0 0 1 1 1 0 IncA protein MAD PF05557.8 KFP06389.1 - 0.027 12.5 6.0 0.033 12.3 4.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.6 KFP06389.1 - 0.058 13.2 1.3 0.058 13.2 0.9 1.6 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KFP06389.1 - 0.066 13.0 0.4 0.077 12.8 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 KFP06389.1 - 0.091 12.7 6.0 0.12 12.3 4.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 KFP06389.1 - 0.1 12.4 9.9 0.14 12.0 6.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Uds1 PF15456.1 KFP06389.1 - 0.14 12.1 6.0 0.2 11.6 4.2 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Atg14 PF10186.4 KFP06389.1 - 0.17 10.8 8.2 0.22 10.4 5.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF947 PF06102.7 KFP06389.1 - 0.18 11.6 5.9 0.21 11.3 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Adeno_PIX PF03955.9 KFP06389.1 - 0.19 12.2 0.8 0.23 12.0 0.5 1.1 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) BCAS2 PF05700.6 KFP06389.1 - 0.19 11.1 4.4 0.26 10.7 3.0 1.3 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) AKNA PF12443.3 KFP06389.1 - 0.25 11.3 4.5 1.4 9.0 3.1 1.9 1 1 0 1 1 1 0 AT-hook-containing transcription factor Syntaxin-6_N PF09177.6 KFP06389.1 - 0.32 11.4 3.2 0.56 10.6 2.2 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 KFP06389.1 - 0.32 8.7 1.6 0.36 8.6 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KFP06389.1 - 0.45 10.1 5.3 0.57 9.8 3.7 1.1 1 0 0 1 1 1 0 Mnd1 family TSC22 PF01166.13 KFP06389.1 - 0.46 10.4 3.1 0.7 9.8 1.3 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF972 PF06156.8 KFP06389.1 - 0.47 10.8 5.1 1.1 9.6 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HlyD PF00529.15 KFP06389.1 - 0.56 9.4 4.6 0.68 9.1 3.2 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DivIC PF04977.10 KFP06389.1 - 0.66 9.5 8.8 0.55 9.7 2.7 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF342 PF03961.8 KFP06389.1 - 0.96 7.7 3.8 1.1 7.6 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 KFP06389.1 - 0.98 9.2 3.7 1.3 8.8 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NYD-SP28_assoc PF14775.1 KFP06389.1 - 1.2 8.8 4.0 0.48 10.1 0.6 2.0 2 1 0 2 2 2 0 Sperm tail C-terminal domain FlxA PF14282.1 KFP06389.1 - 1.4 8.9 5.8 2.9 7.8 4.0 1.7 1 1 0 1 1 1 0 FlxA-like protein YscO PF07321.7 KFP06389.1 - 1.8 8.3 11.0 2.8 7.7 4.0 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO HALZ PF02183.13 KFP06389.1 - 2.3 7.9 6.9 4.1 7.2 2.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 KFP06389.1 - 2.5 7.9 10.6 0.36 10.6 3.5 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Striatin PF08232.7 KFP06389.1 - 3.6 7.9 9.3 14 5.9 6.5 1.8 1 1 0 1 1 1 0 Striatin family DUF724 PF05266.9 KFP06389.1 - 3.9 7.0 7.3 4.8 6.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4140 PF13600.1 KFP06389.1 - 4.9 7.6 7.6 34 4.9 4.9 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PDEase_I PF00233.14 KFP06390.1 - 4.3e-104 347.4 7.2 4.3e-104 347.4 5.0 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ras PF00071.17 KFP06391.1 - 1.4e-61 206.5 0.8 1.7e-61 206.3 0.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06391.1 - 8.1e-19 68.2 0.0 1.2e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06391.1 - 1.3e-14 53.8 0.1 1.7e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFP06391.1 - 5.2e-06 25.8 0.1 6.3e-05 22.2 0.0 2.0 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFP06391.1 - 5.6e-05 22.3 0.1 7.1e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP06391.1 - 0.00014 21.4 0.0 0.00053 19.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP06391.1 - 0.0037 17.1 0.0 0.0062 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP06391.1 - 0.01 15.0 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 KFP06391.1 - 0.018 14.9 0.1 0.043 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KFP06391.1 - 0.061 12.3 0.0 0.77 8.7 0.0 2.2 2 0 0 2 2 2 0 Septin G-alpha PF00503.15 KFP06391.1 - 0.079 11.6 0.5 4 6.0 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_17 PF13207.1 KFP06391.1 - 0.087 13.6 0.1 2.2 9.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain GILT PF03227.11 KFP06392.1 - 2.5e-17 62.7 0.1 3.9e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) SH2 PF00017.19 KFP06393.1 - 7.8e-41 137.7 0.1 9.9e-20 70.1 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.22 KFP06393.1 - 2e-25 89.1 1.4 7.6e-25 87.3 0.0 2.4 2 1 1 3 3 3 1 RhoGAP domain SH3_1 PF00018.23 KFP06393.1 - 2.6e-05 23.5 0.3 0.0039 16.5 0.0 3.3 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 KFP06393.1 - 0.0053 16.3 0.3 0.023 14.2 0.2 2.2 2 1 0 2 2 2 1 Variant SH3 domain ATG11 PF10377.4 KFP06393.1 - 0.0059 16.5 0.7 0.0059 16.5 0.5 1.8 2 0 0 2 2 2 1 Autophagy-related protein 11 SH3_2 PF07653.12 KFP06393.1 - 0.007 15.8 0.3 0.028 13.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain CENP-Q PF13094.1 KFP06393.1 - 0.082 12.9 14.5 0.11 12.4 9.4 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1908 PF08926.6 KFP06394.1 - 4.8e-154 511.1 0.3 4.8e-154 511.1 0.2 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF1908) Pkinase PF00069.20 KFP06394.1 - 5.2e-65 219.1 0.0 1.5e-64 217.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06394.1 - 1.4e-27 96.4 0.0 3.1e-27 95.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PDZ PF00595.19 KFP06394.1 - 3.3e-08 33.5 0.0 7.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP06394.1 - 3.5e-06 26.8 0.0 7.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.1 KFP06394.1 - 4.2e-05 22.6 0.0 0.00077 18.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP06394.1 - 0.00097 18.9 0.0 0.074 12.7 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 KFP06394.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain RIO1 PF01163.17 KFP06394.1 - 0.037 13.3 0.1 0.037 13.3 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 KFP06394.1 - 0.22 10.3 0.2 0.4 9.4 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Arrestin_N PF00339.24 KFP06395.1 - 5.8e-39 133.2 0.0 7e-38 129.7 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFP06395.1 - 4e-26 91.7 0.0 1.3e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.10 KFP06395.1 - 0.0024 16.7 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 LDB19 PF13002.2 KFP06395.1 - 0.07 12.6 0.0 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 Arrestin_N terminal like DUF4601 PF15373.1 KFP06396.1 - 1.5e-62 211.9 14.8 1.9e-62 211.5 10.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4601) PEX11 PF05648.9 KFP06397.1 - 8.4e-38 129.8 0.1 9.2e-38 129.7 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ATP_synt_I PF03899.10 KFP06397.1 - 0.043 13.9 1.6 0.048 13.8 0.4 1.6 1 1 1 2 2 2 0 ATP synthase I chain OAD_gamma PF04277.8 KFP06397.1 - 0.056 13.8 0.0 0.087 13.2 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Kelch_1 PF01344.20 KFP06398.1 - 2.9e-48 161.1 1.5 2.8e-11 42.7 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFP06398.1 - 4.9e-30 102.4 5.7 1e-07 31.8 0.2 6.3 1 1 5 6 6 6 5 Kelch motif BACK PF07707.10 KFP06398.1 - 2.5e-29 101.1 0.8 4.4e-29 100.3 0.3 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.26 KFP06398.1 - 7.1e-27 93.5 0.2 1.3e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 KFP06398.1 - 6.4e-25 86.6 1.9 5e-07 29.7 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP06398.1 - 1.5e-20 72.6 2.3 2.6e-06 27.1 0.0 6.0 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP06398.1 - 1.4e-19 69.0 5.6 5.9e-05 22.6 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KFP06398.1 - 5e-15 55.0 1.9 7.5e-07 28.9 0.0 6.2 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.3 KFP06398.1 - 0.00046 19.4 0.1 0.00081 18.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) HTH_12 PF08461.5 KFP06398.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain PQQ_3 PF13570.1 KFP06398.1 - 0.14 12.5 6.2 2.8 8.3 0.0 3.6 5 0 0 5 5 2 0 PQQ-like domain Rax2 PF12768.2 KFP06398.1 - 0.18 10.9 0.1 2.3 7.3 0.0 2.2 1 1 0 2 2 2 0 Cortical protein marker for cell polarity RhoGEF PF00621.15 KFP06399.1 - 4.3e-36 124.4 3.0 4.3e-36 124.4 2.1 2.4 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFP06399.1 - 8.7e-07 29.0 0.0 3.3e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 PH domain EAP30 PF04157.11 KFP06400.1 - 0.029 13.5 2.3 3.9 6.5 0.5 2.5 1 1 1 2 2 2 0 EAP30/Vps36 family PLC-beta_C PF08703.5 KFP06400.1 - 0.051 13.2 14.6 0.76 9.4 0.6 2.2 2 0 0 2 2 2 0 PLC-beta C terminal Baculo_PEP_C PF04513.7 KFP06400.1 - 0.061 13.1 1.0 0.21 11.3 0.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliT PF05400.8 KFP06400.1 - 0.11 12.8 11.8 0.12 12.8 1.5 2.3 2 0 0 2 2 2 0 Flagellar protein FliT IZUMO PF15005.1 KFP06400.1 - 0.14 12.1 3.3 0.29 11.1 1.7 1.9 1 1 1 2 2 2 0 Izumo sperm-egg fusion Lipoprotein_7 PF01540.11 KFP06400.1 - 0.17 10.9 4.0 0.22 10.5 2.8 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Prominin PF05478.6 KFP06400.1 - 0.2 9.1 4.0 0.24 8.8 2.8 1.1 1 0 0 1 1 1 0 Prominin DASH_Duo1 PF08651.5 KFP06400.1 - 0.22 11.1 2.1 1.8 8.1 0.1 2.7 1 1 1 2 2 2 0 DASH complex subunit Duo1 DUF3417 PF11897.3 KFP06400.1 - 0.34 10.8 3.4 1.3 8.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) DUF4298 PF14131.1 KFP06400.1 - 0.99 9.3 4.0 12 5.8 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) Syntaxin-6_N PF09177.6 KFP06400.1 - 1.7 9.1 5.2 5.1 7.5 1.0 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Sas10_Utp3 PF04000.10 KFP06400.1 - 3.4 7.9 11.7 17 5.6 3.3 3.4 3 1 1 4 4 4 0 Sas10/Utp3/C1D family IncA PF04156.9 KFP06400.1 - 5.5 6.5 24.4 0.42 10.1 6.1 2.1 1 1 0 2 2 2 0 IncA protein Syntaxin_2 PF14523.1 KFP06400.1 - 6.2 6.9 9.6 1.3 9.1 2.8 2.4 1 1 0 2 2 2 0 Syntaxin-like protein PilO PF04350.8 KFP06400.1 - 7.8 6.3 10.3 4.2 7.2 0.1 2.7 1 1 2 3 3 3 0 Pilus assembly protein, PilO A2M_comp PF07678.9 KFP06401.1 - 4.4e-80 268.4 1.4 6.6e-80 267.8 0.9 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 KFP06401.1 - 4.2e-36 123.7 1.9 1.6e-33 115.3 0.0 3.6 3 0 0 3 3 3 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 KFP06401.1 - 1.8e-29 101.1 0.2 1.8e-29 101.1 0.1 3.8 5 0 0 5 5 5 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 KFP06401.1 - 3.7e-28 97.5 0.0 1e-27 96.1 0.0 1.9 1 0 0 1 1 1 1 A-macroglobulin receptor Methyltransf_FA PF12248.3 KFP06401.1 - 1.7e-27 95.3 0.1 5.3e-27 93.8 0.1 1.9 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase Thiol-ester_cl PF10569.4 KFP06401.1 - 5.3e-17 60.7 0.1 1.3e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region A2M_N PF01835.14 KFP06401.1 - 1.7e-16 60.2 0.0 7.8e-16 58.1 0.0 2.3 1 0 0 1 1 1 1 MG2 domain Prenyltrans_2 PF13249.1 KFP06401.1 - 9.3e-09 35.6 1.9 0.0027 18.0 0.0 3.2 1 1 2 3 3 3 3 Prenyltransferase-like Kazal_2 PF07648.10 KFP06401.1 - 7.6e-08 32.1 2.7 2.1e-07 30.7 1.9 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Rib PF08428.5 KFP06401.1 - 0.00045 19.9 0.2 0.0094 15.6 0.0 2.8 2 0 0 2 2 2 1 Rib/alpha-like repeat Prenyltrans_1 PF13243.1 KFP06401.1 - 0.0011 18.9 0.1 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 Prenyltransferase-like Kazal_1 PF00050.16 KFP06401.1 - 0.0016 18.4 10.3 0.0018 18.2 6.0 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain 7tm_1 PF00001.16 KFP06402.1 - 1.1e-48 165.5 21.3 1.1e-48 165.5 14.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP06402.1 - 0.00052 19.2 13.1 0.00072 18.7 9.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srw PF10324.4 KFP06402.1 - 0.31 10.1 14.8 0.028 13.5 2.9 2.5 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw PAH PF02671.16 KFP06403.1 - 1.1e-45 153.0 9.5 7.9e-19 67.0 0.2 4.0 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KFP06403.1 - 1.5e-42 143.3 0.5 1.5e-42 143.3 0.3 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor IL3 PF02059.10 KFP06403.1 - 0.064 13.2 1.1 0.84 9.6 0.0 3.0 3 0 0 3 3 3 0 Interleukin-3 Pkinase_Tyr PF07714.12 KFP06404.1 - 5.8e-88 294.3 0.8 7.6e-88 293.9 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06404.1 - 4.4e-45 153.8 0.2 6.2e-45 153.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP06404.1 - 9.2e-40 134.3 0.1 2e-20 72.3 0.1 2.5 2 0 0 2 2 2 2 SH2 domain RIO1 PF01163.17 KFP06404.1 - 0.00071 18.9 2.3 0.0012 18.2 1.6 1.2 1 0 0 1 1 1 1 RIO1 family ADAM_spacer1 PF05986.9 KFP06405.1 - 5.4e-32 110.0 0.0 8.5e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Pep_M12B_propep PF01562.14 KFP06405.1 - 3.8e-27 94.6 0.1 6.2e-27 93.9 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide TSP_1 PF00090.14 KFP06405.1 - 2.2e-18 66.0 83.4 7.2e-07 29.2 5.4 7.4 7 0 0 7 7 7 5 Thrombospondin type 1 domain Reprolysin PF01421.14 KFP06405.1 - 2.3e-12 46.9 0.8 4.6e-11 42.6 0.6 2.5 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease PLAC PF08686.6 KFP06405.1 - 1.2e-10 41.4 9.8 4.7e-10 39.5 6.8 2.2 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain Myosin_head PF00063.16 KFP06406.1 - 7.9e-242 804.1 0.7 1.2e-241 803.5 0.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFP06406.1 - 6.2e-61 205.1 0.1 1.2e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 KFP06406.1 - 9.5e-15 53.9 0.1 3.8e-14 51.9 0.1 2.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP06406.1 - 1.5e-13 49.8 0.4 5.5e-13 48.0 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFP06406.1 - 1.7e-11 43.4 0.1 3.7e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 KFP06406.1 - 0.007 16.5 0.1 0.032 14.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KFP06406.1 - 0.01 14.8 0.1 0.019 13.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KFP06406.1 - 0.014 15.4 0.0 0.082 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain IQ PF00612.22 KFP06406.1 - 0.016 14.8 1.5 0.053 13.1 1.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif ABC_tran PF00005.22 KFP06406.1 - 0.048 13.9 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 KFP06406.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ATP_bind_2 PF03668.10 KFP06406.1 - 0.14 11.2 0.5 0.47 9.4 0.1 2.0 2 0 0 2 2 2 0 P-loop ATPase protein family LRR_4 PF12799.2 KFP06407.1 - 1.4e-14 53.2 16.6 1.1e-08 34.4 3.9 3.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP06407.1 - 2.8e-09 36.5 18.0 3.7e-07 29.8 3.2 2.8 1 1 2 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 KFP06407.1 - 3.4e-08 33.2 0.2 4.5e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KFP06407.1 - 1.7e-06 27.2 10.0 0.19 12.0 0.2 5.4 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 KFP06407.1 - 1.8e-05 24.3 11.5 0.0047 16.8 0.4 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KFP06407.1 - 0.00079 19.1 14.1 0.017 15.0 0.3 4.8 5 1 0 5 5 5 2 Leucine Rich Repeat Ceramidase PF05875.7 KFP06408.1 - 7.3e-59 199.0 17.3 8.9e-59 198.7 12.0 1.0 1 0 0 1 1 1 1 Ceramidase AMP-binding PF00501.23 KFP06409.1 - 2.7e-80 269.8 0.0 3.2e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Carla_C4 PF01623.12 KFP06409.1 - 0.04 13.6 2.0 0.1 12.3 1.4 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Peptidase_C1 PF00112.18 KFP06410.1 - 4.3e-54 183.7 0.1 6.8e-54 183.0 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KFP06410.1 - 5.6e-16 58.5 1.1 9.1e-16 57.8 0.8 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KFP06410.1 - 0.057 11.9 0.2 0.099 11.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase C1-like family UPF0556 PF10572.4 KFP06411.1 - 7e-80 265.7 0.0 7.5e-80 265.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 DUF758 PF05527.6 KFP06412.1 - 2.6e-96 320.5 3.3 2.9e-96 320.4 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) DUF3877 PF12993.2 KFP06412.1 - 0.0059 16.1 0.5 0.0085 15.6 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3387 PF11867.3 KFP06412.1 - 0.034 13.0 2.0 0.05 12.5 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Pilus_CpaD PF09476.5 KFP06412.1 - 0.066 12.6 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Pico_P2B PF01552.12 KFP06412.1 - 0.098 12.8 0.1 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Picornavirus 2B protein Thioredoxin_6 PF13848.1 KFP06414.1 - 3.1e-23 82.5 0.0 1.2e-19 70.8 0.0 3.4 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin PF00085.15 KFP06414.1 - 3.1e-09 36.4 0.0 1.5e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin DUF1266 PF06889.6 KFP06414.1 - 0.82 9.4 3.0 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DUF1084 PF06454.6 KFP06415.1 - 0.0046 16.0 6.3 0.0057 15.7 2.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) AAA PF00004.24 KFP06416.1 - 5.2e-44 149.6 0.0 1e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP06416.1 - 1.6e-07 31.5 0.8 0.00042 20.4 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KFP06416.1 - 1.7e-07 31.4 0.3 5.4e-06 26.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KFP06416.1 - 6.3e-06 26.1 0.0 7.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFP06416.1 - 9.6e-06 25.3 0.2 0.00025 20.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFP06416.1 - 1.9e-05 23.8 0.0 4.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFP06416.1 - 4.5e-05 24.2 0.2 0.00023 21.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFP06416.1 - 0.00095 19.0 0.0 0.0036 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFP06416.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KFP06416.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFP06416.1 - 0.0023 18.2 0.0 0.013 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 KFP06416.1 - 0.0032 16.4 0.0 0.012 14.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KFP06416.1 - 0.0032 16.9 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFP06416.1 - 0.0035 16.7 0.1 0.018 14.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 KFP06416.1 - 0.0063 16.1 0.0 0.02 14.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFP06416.1 - 0.0082 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 KFP06416.1 - 0.0094 15.5 0.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFP06416.1 - 0.0097 14.6 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Thymidylate_kin PF02223.12 KFP06416.1 - 0.01 15.2 0.2 0.8 9.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.16 KFP06416.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Phage_GP20 PF06810.6 KFP06416.1 - 0.023 14.1 6.3 0.054 12.9 3.1 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 NACHT PF05729.7 KFP06416.1 - 0.026 14.1 0.0 0.14 11.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain TPR_MLP1_2 PF07926.7 KFP06416.1 - 0.026 14.2 1.7 0.052 13.2 1.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_28 PF13521.1 KFP06416.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Med3 PF11593.3 KFP06416.1 - 0.031 13.5 0.2 0.044 13.0 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SKI PF01202.17 KFP06416.1 - 0.036 13.9 0.4 0.4 10.5 0.0 2.5 2 1 1 3 3 3 0 Shikimate kinase KaiC PF06745.8 KFP06416.1 - 0.041 13.0 0.1 0.48 9.4 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.1 KFP06416.1 - 0.044 13.3 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 KFP06416.1 - 0.052 12.0 0.3 5.9 5.2 0.2 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFP06416.1 - 0.055 13.1 0.3 0.4 10.3 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase Syntaxin-6_N PF09177.6 KFP06416.1 - 0.07 13.5 0.5 8.6 6.8 0.3 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal PhoH PF02562.11 KFP06416.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein APG6 PF04111.7 KFP06416.1 - 0.087 11.8 1.9 0.14 11.2 1.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 KFP06416.1 - 0.095 12.6 6.5 0.043 13.7 2.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) AAA_23 PF13476.1 KFP06416.1 - 0.18 12.0 4.7 29 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4140 PF13600.1 KFP06416.1 - 0.22 11.9 1.6 0.58 10.6 1.1 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GvpK PF05121.7 KFP06416.1 - 0.32 10.8 3.2 1.6 8.6 0.5 2.9 3 0 0 3 3 3 0 Gas vesicle protein K TSC22 PF01166.13 KFP06416.1 - 0.59 10.1 4.2 3.2 7.7 1.2 2.8 3 0 0 3 3 2 0 TSC-22/dip/bun family Med4 PF10018.4 KFP06416.1 - 0.94 8.8 4.1 2.1 7.7 2.8 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 IncA PF04156.9 KFP06416.1 - 9.2 5.8 8.9 2.7 7.5 4.2 1.5 2 0 0 2 2 1 0 IncA protein Acetyltransf_1 PF00583.19 KFP06417.1 - 8.2e-11 41.7 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFP06417.1 - 7.2e-10 38.8 0.0 9.8e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFP06417.1 - 0.00028 20.8 0.0 0.00036 20.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFP06417.1 - 0.0062 16.6 0.0 0.007 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFP06417.1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FERM_M PF00373.13 KFP06418.1 - 4.7e-48 162.5 0.6 1.1e-47 161.2 0.1 1.9 2 0 0 2 2 2 1 FERM central domain PH PF00169.24 KFP06418.1 - 8.4e-09 35.5 0.1 2.4e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 PH domain FERM_N PF09379.5 KFP06418.1 - 3.2e-07 30.3 0.0 1.2e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 FERM N-terminal domain Tenui_NCP PF04876.7 KFP06418.1 - 0.022 14.3 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein DDHD PF02862.12 KFP06419.1 - 6.2e-57 192.9 0.0 3.8e-56 190.4 0.0 2.1 1 1 0 1 1 1 1 DDHD domain DUF676 PF05057.9 KFP06419.1 - 0.052 12.8 1.2 3.6 6.8 0.1 2.3 1 1 1 2 2 2 0 Putative serine esterase (DUF676) TGFb_propeptide PF00688.13 KFP06420.1 - 3.4e-76 255.7 3.6 5.5e-76 255.0 2.5 1.3 1 0 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFP06420.1 - 5.4e-41 139.1 0.8 9.7e-41 138.3 0.6 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain CDKN3 PF05706.7 KFP06421.1 - 8.8e-72 239.9 1.4 1.1e-71 239.7 1.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 KFP06421.1 - 1.1e-08 34.7 0.0 1.4e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP06421.1 - 6.6e-06 25.7 0.0 9.3e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFP06421.1 - 0.036 14.1 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFP06421.1 - 0.1 12.8 0.2 4.6 7.4 0.2 2.2 1 1 1 2 2 2 0 Tyrosine phosphatase family zf-C3HC4_3 PF13920.1 KFP06422.1 - 2.8e-11 42.8 11.3 6.7e-11 41.6 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP06422.1 - 0.017 15.1 14.3 0.017 15.1 9.9 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.25 KFP06423.1 - 1.1e-12 47.8 0.1 2.1e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP06423.1 - 1.3e-09 37.7 0.1 2.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PHAT PF09246.5 KFP06423.1 - 0.0001 21.8 0.1 0.063 12.8 0.0 3.0 3 0 0 3 3 3 2 PHAT Telomere_Sde2 PF13019.1 KFP06423.1 - 0.0099 15.5 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 Telomere stability and silencing GTP_cyclohydroI PF01227.17 KFP06424.1 - 1.3e-76 255.8 0.1 1.5e-76 255.6 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KFP06424.1 - 0.00034 20.5 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein MAPKK1_Int PF08923.5 KFP06424.1 - 0.055 13.0 0.2 0.073 12.7 0.1 1.2 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting WD40 PF00400.27 KFP06425.1 - 6.8e-27 92.3 11.7 3.8e-10 39.2 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3639 PF12341.3 KFP06425.1 - 2.3e-11 43.4 0.0 5.7e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) HMG_box PF00505.14 KFP06425.1 - 1.8e-07 31.3 0.0 4.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box eIF2A PF08662.6 KFP06425.1 - 6.8e-07 29.1 0.2 5.6e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFP06425.1 - 0.00049 18.3 0.1 0.044 11.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 HMG_box_2 PF09011.5 KFP06425.1 - 0.0096 16.2 0.0 0.035 14.4 0.0 2.0 1 0 0 1 1 1 1 HMG-box domain Hira PF07569.6 KFP06425.1 - 0.033 13.4 0.3 0.86 8.7 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split SOCS PF12610.3 KFP06426.1 - 2.2e-18 66.3 3.3 2.2e-18 66.3 2.3 2.0 2 0 0 2 2 2 1 Suppressor of cytokine signalling SOCS_box PF07525.11 KFP06426.1 - 1e-12 47.6 0.1 2e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 SOCS box SH2 PF00017.19 KFP06426.1 - 4e-08 32.9 0.0 9.1e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Gal-bind_lectin PF00337.17 KFP06428.1 - 1.9e-36 124.3 0.0 2.4e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin GKAP PF03359.8 KFP06429.1 - 4.1e-11 43.1 2.1 4.1e-11 43.1 1.5 2.3 2 0 0 2 2 2 1 Guanylate-kinase-associated protein (GKAP) protein F-box-like PF12937.2 KFP06430.1 - 0.00064 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFP06430.1 - 0.0085 15.7 0.3 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 F-box domain Atg14 PF10186.4 KFP06431.1 - 1.9e-59 201.0 8.7 2.4e-59 200.7 6.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KFP06431.1 - 2 6.2 6.0 2.5 5.8 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 KFP06431.1 - 4.3 6.4 11.0 6.3 5.8 7.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TBP PF00352.16 KFP06432.1 - 1.2e-57 191.2 0.3 3.3e-32 109.7 0.1 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFP06432.1 - 0.00019 21.3 0.0 0.83 9.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF2346 PF09803.4 KFP06433.1 - 0.0022 17.8 0.2 0.0022 17.8 0.1 8.5 9 2 1 10 10 10 1 Uncharacterized conserved protein (DUF2346) HALZ PF02183.13 KFP06433.1 - 0.0046 16.6 3.1 0.0046 16.6 2.2 14.3 12 3 0 12 12 12 4 Homeobox associated leucine zipper DUF972 PF06156.8 KFP06433.1 - 0.012 15.9 9.8 0.012 15.9 6.8 15.8 5 2 12 17 17 17 0 Protein of unknown function (DUF972) PIG-P PF08510.7 KFP06433.1 - 0.18 11.4 0.5 1.2 8.7 0.0 2.9 2 0 0 2 2 2 0 PIG-P Pellino PF04710.9 KFP06434.1 - 6.2e-227 753.1 0.3 6.9e-227 752.9 0.2 1.0 1 0 0 1 1 1 1 Pellino zf-C3HC4_3 PF13920.1 KFP06434.1 - 1.9e-05 24.2 3.5 0.04 13.5 0.4 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP06434.1 - 0.0017 18.3 7.9 0.27 11.2 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFP06434.1 - 0.0034 17.0 1.9 0.28 10.9 0.2 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFP06434.1 - 0.19 11.5 14.7 1.5 8.6 2.2 3.1 2 1 0 2 2 2 0 Ring finger domain DUF2723 PF11028.3 KFP06435.1 - 2.2e-38 131.5 6.6 2.2e-38 131.5 4.6 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2723) TF_Otx PF03529.8 KFP06436.1 - 9.3e-38 128.3 14.4 9.3e-38 128.3 10.0 2.6 2 1 1 3 3 3 2 Otx1 transcription factor Sec10 PF07393.6 KFP06437.1 - 1.6e-152 509.2 29.8 1.2e-150 503.0 15.2 3.5 2 1 0 2 2 2 1 Exocyst complex component Sec10 S-methyl_trans PF02574.11 KFP06437.1 - 0.042 13.1 0.2 0.079 12.2 0.1 1.4 1 0 0 1 1 1 0 Homocysteine S-methyltransferase Phage_GP20 PF06810.6 KFP06437.1 - 1.5 8.2 13.3 0.032 13.6 2.9 2.6 3 0 0 3 3 3 0 Phage minor structural protein GP20 ACCA PF03255.9 KFP06437.1 - 7.7 6.0 9.8 0.33 10.5 1.1 2.7 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Acetyltransf_1 PF00583.19 KFP06438.1 - 1.2e-17 63.7 0.0 2.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFP06438.1 - 1.4e-10 41.2 0.1 2.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFP06438.1 - 3.4e-09 36.8 0.0 6.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFP06438.1 - 4.1e-09 36.0 0.0 7.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KFP06438.1 - 4.5e-07 29.8 0.0 7.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFP06438.1 - 6e-06 26.4 0.0 9.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFP06438.1 - 0.0003 20.6 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 KFP06438.1 - 0.025 13.3 0.1 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase TGS PF02824.16 KFP06438.1 - 0.14 11.9 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 TGS domain DUF4619 PF15398.1 KFP06439.1 - 4.7e-92 308.5 1.2 5.2e-92 308.4 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4619) EmrE PF13536.1 KFP06440.1 - 7.8e-10 38.9 0.7 7.8e-10 38.9 0.5 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFP06440.1 - 1.5e-06 28.2 5.0 1.5e-06 28.2 3.5 4.1 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 KFP06440.1 - 5.4e-06 25.4 9.8 8.9e-06 24.7 6.8 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KFP06440.1 - 0.0083 15.7 2.2 0.0083 15.7 1.6 2.7 3 0 0 3 3 3 1 Triose-phosphate Transporter family CDC45 PF02724.9 KFP06441.1 - 0.016 13.2 1.0 0.021 12.8 0.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Drc1-Sld2 PF11719.3 KFP06441.1 - 0.018 14.1 1.2 0.029 13.4 0.8 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.7 KFP06441.1 - 0.02 12.8 8.5 0.028 12.3 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KFP06441.1 - 0.14 11.1 4.4 0.24 10.3 3.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 KFP06441.1 - 0.39 10.3 4.8 3.1 7.4 3.8 2.1 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 KFP06441.1 - 0.53 9.7 14.4 1.2 8.6 10.0 1.6 1 0 0 1 1 1 0 Nucleoplasmin RRN3 PF05327.6 KFP06441.1 - 0.71 7.9 4.8 0.98 7.4 3.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_3_Rpc31 PF11705.3 KFP06441.1 - 1 9.2 15.9 1.9 8.3 11.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Paf1 PF03985.8 KFP06441.1 - 1.6 7.3 9.9 2.7 6.6 6.8 1.2 1 0 0 1 1 1 0 Paf1 Sigma70_ner PF04546.8 KFP06441.1 - 3.4 7.2 12.6 6.8 6.2 8.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 KFP06441.1 - 5.3 6.1 14.0 0.26 10.3 4.2 2.5 2 0 0 2 2 2 0 Myc amino-terminal region Actin PF00022.14 KFP06442.1 - 7e-78 261.7 0.0 1.3e-76 257.5 0.0 1.9 1 1 0 1 1 1 1 Actin Proteasome PF00227.21 KFP06443.1 - 5.2e-51 172.6 0.1 6.2e-51 172.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFP06443.1 - 7.2e-15 53.9 0.1 1.2e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RBB1NT PF08169.6 KFP06444.1 - 5.1e-31 106.4 1.6 2.1e-30 104.5 1.1 2.1 1 0 0 1 1 1 1 RBB1NT (NUC162) domain ARID PF01388.16 KFP06444.1 - 5.1e-22 77.5 0.0 1.4e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.3 KFP06444.1 - 1.9e-14 53.1 2.2 5.6e-14 51.5 1.5 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.12 KFP06444.1 - 0.22 11.7 0.0 0.22 11.7 0.0 4.3 5 0 0 5 5 5 0 PWWP domain zf-Tim10_DDP PF02953.10 KFP06445.1 - 8.1e-18 63.4 3.1 1e-17 63.1 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.4 KFP06445.1 - 0.018 14.8 1.1 0.026 14.2 0.6 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TALPID3 PF15324.1 KFP06446.1 - 0 1688.9 66.4 0 1426.4 26.6 2.0 1 1 1 2 2 2 2 Hedgehog signalling target Synaptonemal_3 PF15191.1 KFP06446.1 - 0.058 13.1 6.5 4.4 7.0 0.3 4.0 3 1 1 4 4 4 0 Synaptonemal complex central element protein 3 DUF948 PF06103.6 KFP06446.1 - 0.14 12.0 8.3 0.37 10.6 0.0 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Dapper PF15268.1 KFP06447.1 - 3.7e-202 674.1 29.6 1.9e-155 519.6 16.1 2.0 1 1 1 2 2 2 2 Dapper Ion_trans_2 PF07885.11 KFP06448.1 - 1.9e-33 113.9 18.4 2.5e-18 65.5 0.2 3.0 3 0 0 3 3 3 2 Ion channel DUF1104 PF06518.6 KFP06448.1 - 0.006 16.6 0.9 0.01 15.9 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1104) Carot_N PF09150.5 KFP06448.1 - 0.1 12.3 0.8 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal IclR PF01614.13 KFP06448.1 - 0.11 12.1 0.3 0.3 10.8 0.1 1.7 2 0 0 2 2 2 0 Bacterial transcriptional regulator Mab-21 PF03281.9 KFP06449.1 - 2.5e-09 36.6 1.4 2.5e-09 36.6 1.0 1.6 1 1 0 1 1 1 1 Mab-21 protein FH2 PF02181.18 KFP06450.1 - 3.1e-104 348.8 12.7 3.1e-104 348.8 8.8 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 KFP06450.1 - 4.3e-62 209.0 2.3 4.3e-62 209.0 1.6 2.5 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 KFP06450.1 - 6.9e-49 165.7 0.7 6.9e-49 165.7 0.5 3.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain PP2C_C PF07830.8 KFP06450.1 - 0.0066 16.5 0.6 0.0066 16.5 0.4 3.3 3 0 0 3 3 3 1 Protein serine/threonine phosphatase 2C, C-terminal domain Fe_bilin_red PF05996.7 KFP06450.1 - 0.011 15.1 4.5 0.019 14.4 2.1 2.1 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase Herpes_teg_N PF04843.7 KFP06450.1 - 0.022 14.2 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Totivirus_coat PF05518.6 KFP06450.1 - 6.5 4.4 5.4 10 3.8 3.8 1.2 1 0 0 1 1 1 0 Totivirus coat protein Pro_racemase PF05544.6 KFP06451.1 - 7.3e-57 192.6 0.1 8.2e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 Proline racemase DUF766 PF05571.7 KFP06452.1 - 9.1e-87 291.0 12.8 1e-59 202.3 6.9 1.9 2 0 0 2 2 2 2 Protein of unknown function (DUF766) Pex24p PF06398.6 KFP06453.1 - 0.24 10.1 9.1 0.026 13.3 0.8 2.2 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Hema_stalk PF08720.5 KFP06453.1 - 0.28 10.6 2.6 0.59 9.6 1.7 1.7 1 1 0 1 1 1 0 Influenza C hemagglutinin stalk PSP1 PF04468.7 KFP06453.1 - 0.32 10.9 6.7 0.17 11.9 0.9 2.8 1 1 1 2 2 2 0 PSP1 C-terminal conserved region GAS PF13851.1 KFP06453.1 - 0.61 9.2 29.5 0.77 8.9 3.5 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 KFP06453.1 - 1.4 7.8 19.1 1.1 8.1 2.6 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3496 PF12001.3 KFP06453.1 - 2 8.6 14.9 0.078 13.2 1.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3496) Fib_alpha PF08702.5 KFP06453.1 - 2.4 8.2 13.8 4.5 7.3 6.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CemA PF03040.9 KFP06453.1 - 5.2 6.5 14.4 0.11 12.0 1.9 2.1 1 1 1 2 2 2 0 CemA family DEAD_assoc PF08494.6 KFP06454.1 - 0.015 15.0 2.4 0.018 14.7 1.6 1.3 1 0 0 1 1 1 0 DEAD/H associated AKNA PF12443.3 KFP06454.1 - 0.16 12.0 4.1 0.23 11.4 2.3 1.8 1 1 0 1 1 1 0 AT-hook-containing transcription factor GvpO PF05800.6 KFP06454.1 - 0.38 10.6 5.7 0.18 11.7 1.0 2.2 1 1 0 2 2 2 0 Gas vesicle synthesis protein GvpO CDC37_N PF03234.9 KFP06454.1 - 2.1 8.6 10.0 3.1 8.1 6.9 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding COG2 PF06148.6 KFP06454.1 - 9.4 6.1 8.0 11 5.8 2.6 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Reticulon PF02453.12 KFP06455.1 - 4.6e-59 198.8 8.1 6.4e-59 198.3 5.6 1.2 1 0 0 1 1 1 1 Reticulon EI24 PF07264.6 KFP06455.1 - 3.7 6.9 10.6 7.8 5.8 0.9 2.1 1 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Pecanex_C PF05041.10 KFP06457.1 - 1.1e-50 171.8 0.0 1.9e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) adh_short PF00106.20 KFP06458.1 - 3.3e-31 108.4 0.1 4.2e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP06458.1 - 5.9e-14 52.1 0.0 8.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFP06458.1 - 1e-13 51.6 0.0 1.3e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.14 KFP06458.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KFP06458.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding DUF3341 PF11821.3 KFP06458.1 - 0.14 11.5 0.2 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) PP2C PF00481.16 KFP06459.1 - 1.4e-87 293.2 0.0 1.8e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.8 KFP06459.1 - 5.9e-36 122.4 0.1 1.3e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain PP2C_2 PF13672.1 KFP06459.1 - 0.00013 21.3 0.0 0.00027 20.4 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C ATG16 PF08614.6 KFP06460.1 - 0.0093 15.8 5.5 0.0093 15.8 3.8 3.5 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 KFP06460.1 - 8.9 6.4 28.8 0.24 11.5 0.6 3.7 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Apc3 PF12895.2 KFP06461.1 - 0.048 13.7 0.5 0.078 13.1 0.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Homeobox PF00046.24 KFP06462.1 - 1.3e-14 53.5 1.4 3.3e-14 52.2 0.2 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KFP06462.1 - 2.8e-12 46.1 0.5 6.2e-12 45.0 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFP06462.1 - 0.0017 17.3 0.2 0.0079 15.2 0.0 2.1 1 1 1 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 KFP06462.1 - 0.0068 16.2 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix KilA-N PF04383.8 KFP06462.1 - 0.15 11.6 0.6 1.1 8.8 0.1 2.0 2 0 0 2 2 2 0 KilA-N domain Homeobox PF00046.24 KFP06463.1 - 3.6e-13 48.9 1.0 7.9e-13 47.8 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP06463.1 - 4.2e-07 29.5 0.3 1.1e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFP06463.1 - 0.045 12.8 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MAT1 PF06391.8 KFP06464.1 - 1e-82 276.5 20.5 1.2e-82 276.3 14.2 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 AAA_23 PF13476.1 KFP06464.1 - 0.17 12.2 11.0 0.2 11.9 7.6 1.3 1 0 0 1 1 1 0 AAA domain DUF763 PF05559.6 KFP06464.1 - 0.45 9.4 3.3 0.59 9.0 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Activator_LAG-3 PF11498.3 KFP06464.1 - 0.98 8.0 10.9 1.3 7.6 7.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Orbi_VP5 PF00901.12 KFP06464.1 - 1.6 6.8 11.5 2.1 6.4 8.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 RNA_pol_Rpb1_5 PF04998.12 KFP06464.1 - 8.5 5.5 6.8 12 5.0 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Met_10 PF02475.11 KFP06465.1 - 9.5e-28 97.1 0.0 1.3e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Aa_trans PF01490.13 KFP06466.1 - 5.5e-75 252.3 40.9 6.9e-75 252.0 28.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein C2 PF00168.25 KFP06467.1 - 8.7e-13 47.9 0.2 1.1e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 C2 domain Aida_C2 PF14186.1 KFP06467.1 - 0.09 12.0 0.1 0.55 9.4 0.1 1.8 1 1 1 2 2 2 0 Cytoskeletal adhesion C1_1 PF00130.17 KFP06468.1 - 1.6e-31 107.8 31.0 4.2e-16 58.4 4.6 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 KFP06468.1 - 0.0078 16.0 2.2 0.0078 16.0 1.5 2.8 2 1 0 2 2 2 1 Double zinc ribbon DUF2321 PF10083.4 KFP06468.1 - 0.12 11.8 3.4 0.56 9.7 0.7 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-CCHC_4 PF14392.1 KFP06468.1 - 0.34 10.6 0.1 0.34 10.6 0.1 3.6 4 0 0 4 4 4 0 Zinc knuckle zf-ribbon_3 PF13248.1 KFP06468.1 - 0.59 9.4 5.5 7.1 5.9 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain FYVE_2 PF02318.11 KFP06468.1 - 0.88 9.4 20.0 2 8.3 5.6 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger HLH PF00010.21 KFP06469.1 - 5.7e-05 22.7 0.3 6.8e-05 22.4 0.2 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HIF-1 PF11413.3 KFP06470.1 - 4.9e-17 60.8 7.0 1.2e-16 59.6 4.9 1.7 1 0 0 1 1 1 1 Hypoxia-inducible factor-1 C2 PF00168.25 KFP06471.1 - 1.3e-15 57.0 0.0 5.2e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain SERTA PF06031.8 KFP06472.1 - 3e-14 52.0 1.6 4.5e-14 51.4 1.1 1.3 1 0 0 1 1 1 1 SERTA motif Ion_trans PF00520.26 KFP06473.1 - 3.1e-25 88.5 3.8 6e-25 87.6 2.6 1.5 1 0 0 1 1 1 1 Ion transport protein PAS_9 PF13426.1 KFP06473.1 - 1.6e-16 60.5 0.0 6.6e-16 58.5 0.0 2.1 2 0 0 2 2 2 1 PAS domain Ion_trans_2 PF07885.11 KFP06473.1 - 1.4e-13 50.3 3.3 4.9e-13 48.5 2.3 2.0 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.24 KFP06473.1 - 1.9e-12 46.8 0.0 3.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PAS PF00989.19 KFP06473.1 - 5.3e-07 29.4 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 KFP06473.1 - 0.0028 17.7 0.0 0.0064 16.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold Ion_trans_N PF08412.5 KFP06473.1 - 0.0037 16.5 0.1 0.011 15.0 0.1 1.8 1 0 0 1 1 1 1 Ion transport protein N-terminal Cupin_2 PF07883.6 KFP06473.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain PAS_4 PF08448.5 KFP06473.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold NPV_P10 PF05531.7 KFP06473.1 - 0.013 15.7 1.6 0.045 14.0 1.1 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Cupin_3 PF05899.7 KFP06473.1 - 0.046 13.0 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PAS_10 PF13596.1 KFP06473.1 - 0.076 13.2 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 PAS domain Ras PF00071.17 KFP06474.1 - 1.4e-48 164.3 0.0 1.6e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06474.1 - 4.3e-17 62.7 0.0 6.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06474.1 - 2.1e-05 23.8 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MobB PF03205.9 KFP06474.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Cys_knot PF00007.17 KFP06475.1 - 1.5e-17 63.5 7.1 1.8e-17 63.3 4.9 1.1 1 0 0 1 1 1 1 Cystine-knot domain DAN PF03045.10 KFP06475.1 - 0.0076 15.6 1.9 0.01 15.2 1.3 1.4 1 1 0 1 1 1 1 DAN domain B56 PF01603.15 KFP06476.1 - 1.3e-172 574.0 9.3 1.5e-172 573.8 6.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 KFP06476.1 - 0.12 11.7 5.9 1.2 8.5 0.5 3.3 3 2 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal WD40 PF00400.27 KFP06477.1 - 5.5e-18 64.0 8.2 7.5e-05 22.4 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PAP2 PF01569.16 KFP06478.1 - 4.2e-18 65.2 5.4 4.2e-18 65.2 3.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily ERbeta_N PF12497.3 KFP06479.1 - 2.2e-35 120.7 8.2 4.3e-35 119.8 5.7 1.5 1 0 0 1 1 1 1 Estrogen receptor beta Hormone_recep PF00104.25 KFP06479.1 - 1e-33 116.2 0.8 1.6e-33 115.5 0.5 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP06479.1 - 1.4e-31 108.5 13.3 2.7e-31 107.5 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) FTHFS PF01268.14 KFP06480.1 - 1.4e-260 865.0 0.0 1.8e-260 864.7 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KFP06480.1 - 1.3e-67 225.9 1.7 1.3e-67 225.9 1.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KFP06480.1 - 2e-32 111.6 0.4 5.1e-32 110.3 0.3 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain BTB PF00651.26 KFP06482.1 - 2e-20 72.8 0.1 5.3e-20 71.4 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.21 KFP06482.1 - 8.3e-08 32.1 16.7 0.0001 22.4 0.6 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP06482.1 - 4.8e-07 29.6 13.8 0.0021 18.2 0.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP06482.1 - 7.5e-06 25.9 7.7 0.013 15.5 1.3 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP06482.1 - 0.00096 19.2 5.2 0.65 10.1 1.5 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFP06482.1 - 0.0018 17.8 2.5 0.038 13.6 0.1 2.6 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-FCS PF06467.9 KFP06482.1 - 0.069 12.7 1.8 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif PyrI_C PF02748.10 KFP06482.1 - 0.078 12.4 0.8 12 5.4 0.2 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 KFP06482.1 - 0.17 12.0 6.5 0.43 10.7 0.1 2.9 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KFP06482.1 - 0.21 11.8 4.9 0.2 11.9 0.3 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FYVE PF01363.16 KFP06482.1 - 0.28 11.1 6.3 4.3 7.2 2.4 2.5 2 0 0 2 2 2 0 FYVE zinc finger BTB PF00651.26 KFP06483.1 - 5.5e-19 68.1 1.3 5.5e-19 68.1 0.9 1.9 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KFP06483.1 - 2.4e-13 49.3 61.8 0.0058 16.8 0.1 10.5 10 1 0 10 10 10 7 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP06483.1 - 6.1e-09 35.7 67.8 0.012 15.9 0.3 10.5 9 1 1 10 10 10 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP06483.1 - 2.8e-07 30.4 51.3 0.00026 21.1 2.3 9.3 9 1 0 9 9 9 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP06483.1 - 0.0015 18.5 0.3 0.0081 16.2 0.2 8.8 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP06483.1 - 0.0028 17.7 43.1 0.095 12.9 0.3 9.2 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP06483.1 - 3.7 7.7 46.9 0.18 11.9 2.2 7.5 4 2 5 9 9 9 0 Drought induced 19 protein (Di19), zinc-binding HSP70 PF00012.15 KFP06484.1 - 1.3e-275 915.0 11.3 1.4e-275 914.9 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFP06484.1 - 2e-17 62.7 0.7 7.7e-16 57.5 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 KFP06484.1 - 0.00014 21.6 1.0 0.064 13.0 0.0 3.6 2 2 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.11 KFP06484.1 - 0.00024 20.7 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KFP06484.1 - 0.0048 16.0 2.3 0.019 14.0 0.1 2.7 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 KFP06484.1 - 0.015 14.1 0.1 0.15 10.8 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain TFIIB PF00382.14 KFP06485.1 - 3.2e-33 113.3 0.0 1.1e-15 57.1 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KFP06485.1 - 1.8e-26 92.2 12.0 1.8e-26 92.2 8.3 2.9 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KFP06485.1 - 1.4e-08 34.4 0.3 0.00022 20.7 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain PHR PF08005.7 KFP06486.1 - 1.9e-46 157.9 0.9 3.3e-46 157.1 0.6 1.4 1 0 0 1 1 1 1 PHR domain BTB PF00651.26 KFP06486.1 - 1.8e-24 85.8 0.1 1.8e-23 82.6 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFP06486.1 - 5.2e-07 29.4 3.1 9.5e-07 28.6 0.7 2.4 2 1 0 2 2 2 1 BTB And C-terminal Kelch Ribosomal_60s PF00428.14 KFP06487.1 - 0.092 13.1 2.6 0.11 12.8 1.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein NUDIX PF00293.23 KFP06488.1 - 1.1e-16 60.7 0.0 1.3e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain ESPR PF13018.1 KFP06488.1 - 0.019 14.5 0.4 0.036 13.7 0.3 1.4 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system EGF PF00008.22 KFP06489.1 - 4.5e-69 227.8 283.6 2.2e-08 33.8 5.4 18.8 19 0 0 19 19 19 14 EGF-like domain MNNL PF07657.8 KFP06489.1 - 4.2e-27 93.8 1.2 4.2e-27 93.8 0.8 5.2 6 0 0 6 6 6 1 N terminus of Notch ligand DSL PF01414.14 KFP06489.1 - 9.2e-27 92.8 6.4 9.2e-27 92.8 4.4 13.3 10 3 5 15 15 15 1 Delta serrate ligand hEGF PF12661.2 KFP06489.1 - 6.9e-17 60.2 169.2 0.0072 16.3 4.3 19.3 18 0 0 18 18 18 13 Human growth factor-like EGF EGF_2 PF07974.8 KFP06489.1 - 1.9e-15 56.7 326.3 0.0061 16.6 5.0 20.1 20 0 0 20 20 20 14 EGF-like domain EGF_CA PF07645.10 KFP06489.1 - 4e-06 26.7 21.5 4.3e-05 23.4 5.0 19.8 9 4 11 20 20 20 10 Calcium-binding EGF domain DUF2920 PF11144.3 KFP06489.1 - 0.02 13.9 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) HSA PF07529.8 KFP06489.1 - 0.18 11.6 0.8 0.48 10.2 0.6 1.7 1 0 0 1 1 1 0 HSA PepSY_TM_2 PF13703.1 KFP06489.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix SERTA PF06031.8 KFP06490.1 - 1.5e-18 65.7 2.6 1.5e-18 65.7 1.8 1.8 2 0 0 2 2 2 1 SERTA motif Glycohydro_20b2 PF14845.1 KFP06490.1 - 0.039 14.5 0.2 0.058 14.0 0.2 1.4 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like Clathrin_bdg PF15045.1 KFP06491.1 - 3.7e-24 84.0 0.2 8e-24 82.9 0.2 1.6 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking PDZ PF00595.19 KFP06493.1 - 2e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) NTPase_1 PF03266.10 KFP06495.1 - 1.2e-55 187.7 0.2 1.4e-55 187.5 0.2 1.0 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.1 KFP06495.1 - 0.088 12.7 0.2 2.3 8.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFP06495.1 - 0.091 12.9 0.1 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KFP06495.1 - 0.12 12.0 0.2 0.25 11.0 0.1 1.8 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pecanex_C PF05041.10 KFP06496.1 - 1.8e-121 403.4 0.0 3.3e-121 402.6 0.0 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Pkinase_Tyr PF07714.12 KFP06497.1 - 6e-31 107.4 0.0 1.1e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06497.1 - 1.7e-24 86.4 0.0 3.6e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DUF3552 PF12072.3 KFP06497.1 - 0.046 12.9 13.3 0.079 12.1 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.9 KFP06497.1 - 5 7.0 10.1 9.8 6.0 7.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CN_hydrolase PF00795.17 KFP06498.1 - 9.8e-31 106.5 0.0 1.2e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.20 KFP06499.1 - 1.3e-65 221.1 0.0 1.4e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06499.1 - 3.9e-33 114.6 0.0 4.8e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06499.1 - 2.1e-07 30.2 0.0 3.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP06499.1 - 0.0066 16.2 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFP06499.1 - 0.067 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFP06499.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CagZ PF09053.5 KFP06499.1 - 0.14 11.4 0.1 0.3 10.3 0.1 1.5 1 0 0 1 1 1 0 CagZ I-set PF07679.11 KFP06500.1 - 2.6e-160 520.7 0.0 9.5e-16 57.4 0.0 13.3 13 0 0 13 13 13 12 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP06500.1 - 1.4e-105 345.5 4.6 2.3e-11 43.6 0.0 13.2 13 0 0 13 13 13 12 Immunoglobulin domain Ig_3 PF13927.1 KFP06500.1 - 3.2e-81 267.7 27.3 1.5e-09 38.1 0.1 15.0 13 0 0 13 13 13 13 Immunoglobulin domain ig PF00047.20 KFP06500.1 - 1e-58 195.3 9.2 4.3e-07 29.9 0.0 13.2 12 1 0 12 12 12 10 Immunoglobulin domain V-set PF07686.12 KFP06500.1 - 4.3e-56 187.7 15.8 6.6e-06 25.9 0.0 14.1 12 2 1 13 13 13 11 Immunoglobulin V-set domain LRR_8 PF13855.1 KFP06500.1 - 4.8e-29 99.8 6.4 3.1e-11 42.8 0.5 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP06500.1 - 7.1e-15 54.2 2.2 0.0028 17.2 0.0 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) Sp38 PF07354.7 KFP06500.1 - 8.6e-08 31.1 0.0 1.8 7.1 0.0 6.0 8 0 0 8 8 8 3 Zona-pellucida-binding protein (Sp38) LRR_1 PF00560.28 KFP06500.1 - 9.8e-06 24.9 8.1 10 6.5 0.0 7.5 7 0 0 7 7 7 1 Leucine Rich Repeat LRRNT PF01462.13 KFP06500.1 - 0.15 11.5 7.5 0.034 13.6 2.3 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Ca_chan_IQ PF08763.6 KFP06500.1 - 0.28 10.4 0.4 0.79 9.0 0.3 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Sulfatase PF00884.18 KFP06501.1 - 3.1e-85 286.0 0.0 4.2e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFP06501.1 - 8.7e-53 178.1 0.1 1.4e-52 177.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFP06501.1 - 7.7e-12 45.2 0.1 5e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFP06501.1 - 0.084 11.2 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase PF00884.18 KFP06502.1 - 2.6e-42 145.0 0.0 4.4e-42 144.3 0.0 1.3 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFP06502.1 - 3e-05 24.3 0.2 6.2e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KFP06502.1 - 0.00027 20.3 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 KFP06502.1 - 0.019 13.7 0.7 0.026 13.2 0.5 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3040 PF11239.3 KFP06502.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) ERG4_ERG24 PF01222.12 KFP06503.1 - 1.8e-182 606.7 10.6 2.2e-182 606.4 7.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family LBR_tudor PF09465.5 KFP06503.1 - 8.6e-33 111.7 0.3 1.8e-32 110.7 0.2 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1295 PF06966.7 KFP06503.1 - 3.2e-06 26.6 0.4 7.8e-06 25.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KFP06503.1 - 1.6e-05 24.9 0.1 9.4e-05 22.4 0.1 2.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 KFP06503.1 - 0.0028 17.8 0.3 0.0028 17.8 0.2 2.6 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Macoilin PF09726.4 KFP06503.1 - 0.062 11.5 8.8 0.095 10.9 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1325 PF07039.6 KFP06503.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain WH1 PF00568.18 KFP06504.1 - 6e-40 135.4 0.2 8.3e-40 134.9 0.1 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.6 KFP06504.1 - 2.6e-20 71.4 4.9 2.6e-20 71.4 3.4 2.5 2 0 0 2 2 2 1 VASP tetramerisation domain CAF-1_p150 PF11600.3 KFP06504.1 - 0.6 9.4 62.4 0.012 15.0 31.1 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SRP9-21 PF05486.7 KFP06505.1 - 3.3e-12 45.9 0.1 3.7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF3128 PF11326.3 KFP06505.1 - 0.033 14.3 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) DUF221 PF02714.10 KFP06506.1 - 1.5e-88 296.8 21.2 1.5e-88 296.8 14.7 3.3 2 1 1 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFP06506.1 - 3.8e-22 78.5 1.9 3.8e-22 78.5 1.3 4.6 4 1 0 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFP06506.1 - 3.2e-14 53.2 2.6 7e-14 52.1 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 KFP06506.1 - 8.4e-05 22.1 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MpPF26 PF07666.6 KFP06506.1 - 0.0034 17.2 2.9 0.0034 17.2 2.0 4.8 5 0 0 5 5 5 1 M penetrans paralogue family 26 RRM_6 PF14259.1 KFP06506.1 - 0.069 13.1 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TGFb_propeptide PF00688.13 KFP06507.1 - 6.9e-28 97.5 1.2 1.2e-27 96.7 0.9 1.3 1 1 0 1 1 1 1 TGF-beta propeptide TGF_beta PF00019.15 KFP06507.1 - 5.2e-11 42.7 4.7 3.4e-08 33.6 3.3 2.4 1 1 0 1 1 1 1 Transforming growth factor beta like domain Telomere_Sde2 PF13019.1 KFP06508.1 - 1e-31 109.7 1.7 1.6e-31 109.2 1.1 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Virul_Fac PF10139.4 KFP06508.1 - 0.013 13.4 0.7 0.016 13.1 0.5 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor DUF3456 PF11938.3 KFP06508.1 - 0.029 14.3 1.1 0.049 13.6 0.8 1.4 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP PVL_ORF50 PF07768.6 KFP06508.1 - 0.062 13.2 3.9 0.1 12.5 2.7 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Ferritin_2 PF13668.1 KFP06508.1 - 0.12 12.2 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Ferritin-like domain Histone PF00125.19 KFP06509.1 - 1.7e-33 114.5 0.2 2e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFP06509.1 - 6.2e-05 23.1 0.0 8.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KFP06509.1 - 0.013 14.7 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 KFP06509.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GOLD_2 PF13897.1 KFP06510.1 - 6.7e-69 230.3 5.3 6.7e-69 230.3 3.7 3.1 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking ACBP PF00887.14 KFP06510.1 - 1.6e-15 56.5 0.0 5.2e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein PAT1 PF09770.4 KFP06510.1 - 0.95 7.6 28.7 1.6 6.8 19.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 KFP06510.1 - 2.2 5.9 21.6 0.66 7.6 12.8 1.6 2 0 0 2 2 2 0 Ycf1 U79_P34 PF03064.11 KFP06510.1 - 4.3 6.7 17.9 0.55 9.7 8.2 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 KFP06510.1 - 5.5 6.2 23.8 2.3 7.5 9.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Merozoite_SPAM PF07133.6 KFP06510.1 - 5.7 6.8 32.7 2.1 8.1 13.9 2.4 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Homeobox PF00046.24 KFP06511.1 - 1.1e-11 44.1 0.3 1.4e-11 43.8 0.2 1.1 1 0 0 1 1 1 1 Homeobox domain DIRP PF06584.8 KFP06512.1 - 3.6e-42 142.6 0.1 9.2e-42 141.3 0.1 1.7 1 0 0 1 1 1 1 DIRP FTA4 PF13093.1 KFP06512.1 - 0.022 14.2 2.0 0.053 12.9 1.4 1.8 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 zf-PARP PF00645.13 KFP06513.1 - 8.9e-17 61.1 8.1 9.4e-11 41.8 0.2 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF1109 PF06532.6 KFP06514.1 - 0.0039 16.6 1.4 0.0052 16.2 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1109) Sec23_trunk PF04811.10 KFP06515.1 - 4.7e-81 271.7 0.0 6.8e-81 271.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFP06515.1 - 6.4e-35 118.6 0.1 1.3e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFP06515.1 - 2.4e-30 104.8 0.0 5.6e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KFP06515.1 - 6.7e-16 57.7 0.0 2.3e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 KFP06515.1 - 3.7e-15 55.2 5.8 6.4e-15 54.4 4.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Tyr_Deacylase PF02580.11 KFP06516.1 - 1.7e-41 141.6 0.0 2.1e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Toprim_C_rpt PF13368.1 KFP06516.1 - 0.028 14.9 0.1 0.049 14.1 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Laminin_G_2 PF02210.19 KFP06518.1 - 4.1e-132 434.2 10.4 7e-30 103.6 0.0 5.2 5 0 0 5 5 5 5 Laminin G domain Laminin_G_1 PF00054.18 KFP06518.1 - 7.1e-88 291.3 4.2 8.7e-25 87.2 0.0 6.5 5 1 0 5 5 5 5 Laminin G domain Laminin_G_3 PF13385.1 KFP06518.1 - 2e-19 70.3 4.7 0.00059 20.1 0.0 5.3 5 0 0 5 5 5 5 Concanavalin A-like lectin/glucanases superfamily EGF PF00008.22 KFP06518.1 - 5.2e-08 32.6 18.4 0.00017 21.4 5.3 2.8 2 0 0 2 2 2 2 EGF-like domain DUF1080 PF06439.6 KFP06518.1 - 0.00064 19.6 0.0 6.1 6.6 0.0 3.6 3 0 0 3 3 3 2 Domain of Unknown Function (DUF1080) Yae1_N PF09811.4 KFP06519.1 - 2.4e-08 33.3 18.1 5e-05 22.7 4.9 2.3 2 0 0 2 2 2 2 Essential protein Yae1, N terminal Lipase_GDSL_2 PF13472.1 KFP06520.1 - 1.1e-05 25.6 0.0 2.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family 7tm_1 PF00001.16 KFP06521.1 - 4.5e-39 134.1 28.1 7e-39 133.5 19.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.1 KFP06521.1 - 9.1e-15 54.1 18.2 2.2e-06 27.2 0.3 4.2 2 1 2 4 4 4 4 Leucine rich repeat GnHR_trans PF12369.3 KFP06521.1 - 9.4e-11 42.0 0.2 3.6e-10 40.1 0.1 2.0 2 0 0 2 2 2 1 Gonadotropin hormone receptor transmembrane region LRR_5 PF13306.1 KFP06521.1 - 1.7e-05 24.5 0.1 5.1e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_4 PF12799.2 KFP06521.1 - 7.4e-05 22.2 11.2 0.046 13.3 1.5 4.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP06521.1 - 9.1e-05 21.9 10.5 0.13 12.3 0.1 6.2 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KFP06521.1 - 0.024 14.7 5.9 4.2 7.9 0.4 4.5 4 0 0 4 4 4 0 Leucine rich repeat 7tm_1 PF00001.16 KFP06522.1 - 6.8e-38 130.2 20.2 9.2e-38 129.8 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.1 KFP06522.1 - 2.2e-17 62.5 6.1 7.6e-05 22.3 1.7 4.4 2 2 2 4 4 4 4 Leucine rich repeat LRR_5 PF13306.1 KFP06522.1 - 7.1e-11 41.9 0.1 0.00013 21.6 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) GnHR_trans PF12369.3 KFP06522.1 - 0.00037 20.8 2.3 0.00045 20.6 0.6 1.9 2 0 0 2 2 2 1 Gonadotropin hormone receptor transmembrane region LRR_4 PF12799.2 KFP06522.1 - 0.003 17.1 6.6 0.42 10.2 0.0 4.0 3 2 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP06522.1 - 4.7 7.6 9.5 62 4.2 0.0 6.1 7 1 0 7 7 7 0 Leucine Rich Repeat TFIIA PF03153.8 KFP06523.1 - 2.9e-88 297.2 25.0 5.1e-87 293.2 17.3 2.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Adap_comp_sub PF00928.16 KFP06523.1 - 3.6e-56 190.1 0.7 6.2e-56 189.4 0.5 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Beta_helix PF13229.1 KFP06524.1 - 3.9e-61 205.4 61.2 1.6e-24 86.4 10.6 4.4 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.8 KFP06524.1 - 5.8e-44 150.0 48.5 1.1e-17 64.0 5.0 4.9 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) F-box-like PF12937.2 KFP06524.1 - 2.7e-16 59.0 0.3 5.7e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like zf-UBR PF02207.15 KFP06524.1 - 3.9e-12 45.7 12.7 3.9e-12 45.7 8.8 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.28 KFP06524.1 - 5.1e-08 32.3 2.1 7e-08 31.9 0.2 2.0 2 0 0 2 2 2 1 F-box domain I-set PF07679.11 KFP06525.1 - 8.9e-71 233.8 0.0 1.2e-16 60.2 0.0 6.5 6 0 0 6 6 6 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP06525.1 - 3e-51 171.4 0.0 1.1e-09 38.2 0.0 5.5 5 0 0 5 5 5 5 Immunoglobulin domain fn3 PF00041.16 KFP06525.1 - 1e-45 153.7 20.3 3.5e-15 55.8 1.3 4.4 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.12 KFP06525.1 - 1.5e-33 115.0 2.6 3.1e-06 27.0 0.0 8.1 7 3 0 7 7 7 5 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP06525.1 - 1.6e-32 111.7 1.5 1.7e-07 31.5 0.0 7.3 8 0 0 8 8 7 5 Immunoglobulin domain ig PF00047.20 KFP06525.1 - 2.8e-32 110.6 1.2 3.1e-06 27.2 0.0 8.0 7 2 0 7 7 7 5 Immunoglobulin domain Tissue_fac PF01108.12 KFP06525.1 - 1.6e-09 37.4 3.6 2.9e-06 26.9 0.4 3.6 2 1 1 3 3 3 2 Tissue factor Sp38 PF07354.7 KFP06525.1 - 0.00021 20.0 0.1 3.1 6.3 0.0 4.0 5 0 0 5 5 5 2 Zona-pellucida-binding protein (Sp38) C2-set_2 PF08205.7 KFP06525.1 - 0.00055 19.7 6.8 1.6 8.6 0.0 5.3 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Interfer-bind PF09294.5 KFP06525.1 - 0.006 16.5 0.1 3 7.9 0.0 3.2 3 0 0 3 3 3 1 Interferon-alpha/beta receptor, fibronectin type III V-set_CD47 PF08204.6 KFP06525.1 - 0.008 15.9 0.4 32 4.2 0.0 4.1 4 0 0 4 4 4 0 CD47 immunoglobulin-like domain I-set PF07679.11 KFP06526.1 - 3e-70 232.0 0.1 6.3e-13 48.3 0.0 7.0 8 0 0 8 8 8 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP06526.1 - 4.7e-57 190.0 0.1 1.1e-10 41.4 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 KFP06526.1 - 6.4e-52 173.6 4.8 9.2e-12 44.9 0.0 5.6 5 0 0 5 5 5 5 Fibronectin type III domain Ig_3 PF13927.1 KFP06526.1 - 3.1e-42 142.8 4.8 1.4e-07 31.9 0.0 7.7 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.20 KFP06526.1 - 6.5e-30 103.0 6.5 3e-06 27.2 0.0 7.5 8 0 0 8 8 8 5 Immunoglobulin domain Bravo_FIGEY PF13882.1 KFP06526.1 - 4.5e-27 94.7 4.9 9.3e-27 93.7 3.4 1.6 1 0 0 1 1 1 1 Bravo-like intracellular region V-set PF07686.12 KFP06526.1 - 1.4e-26 92.6 3.3 0.00033 20.5 0.1 7.9 4 4 1 6 6 6 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP06526.1 - 6.3e-09 35.6 1.5 0.12 12.2 0.0 6.0 7 0 0 7 7 7 2 CD80-like C2-set immunoglobulin domain C2-set PF05790.10 KFP06526.1 - 0.0041 17.0 0.5 15 5.6 0.0 4.5 6 0 0 6 6 6 0 Immunoglobulin C2-set domain Receptor_2B4 PF11465.3 KFP06526.1 - 0.0063 16.4 0.3 6.9 6.6 0.0 3.8 3 1 1 4 4 4 1 Natural killer cell receptor 2B4 UBA PF00627.26 KFP06527.1 - 9.8e-08 31.6 0.0 0.046 13.5 0.0 3.7 3 0 0 3 3 3 3 UBA/TS-N domain HBS1_N PF08938.5 KFP06527.1 - 0.054 13.6 0.0 0.42 10.7 0.0 2.4 2 0 0 2 2 2 0 HBS1 N-terminus RNase_T PF00929.19 KFP06527.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Exonuclease Lipase_GDSL_2 PF13472.1 KFP06528.1 - 3e-07 30.7 0.0 6.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4611 PF15387.1 KFP06528.1 - 0.17 12.0 0.8 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) BTB PF00651.26 KFP06529.1 - 5.2e-33 113.3 1.3 1.7e-32 111.6 0.3 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP06529.1 - 2.8e-07 30.5 0.7 2.8e-07 30.5 0.5 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 KFP06529.1 - 0.0052 16.9 0.9 0.73 10.1 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type RNA_pol_3_Rpc31 PF11705.3 KFP06529.1 - 0.0071 16.3 7.0 0.018 14.9 4.8 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 zf-C2H2_4 PF13894.1 KFP06529.1 - 0.0079 16.4 0.4 2.1 8.8 0.0 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 KFP06529.1 - 0.021 14.9 0.2 0.046 13.8 0.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding CDC45 PF02724.9 KFP06529.1 - 0.087 10.8 5.7 0.12 10.4 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 KFP06529.1 - 0.13 10.4 6.8 0.18 10.0 4.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein zf-C2H2_jaz PF12171.3 KFP06529.1 - 0.16 12.1 1.5 50 4.1 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Sigma70_ner PF04546.8 KFP06529.1 - 0.17 11.4 10.3 1.7 8.1 8.2 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Daxx PF03344.10 KFP06529.1 - 0.18 10.2 18.7 0.25 9.7 13.0 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 KFP06529.1 - 0.19 10.8 15.0 0.28 10.2 10.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.6 KFP06529.1 - 0.25 11.1 6.2 0.45 10.2 4.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal BSP_II PF05432.6 KFP06529.1 - 0.29 10.3 19.4 0.47 9.6 13.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 KFP06529.1 - 0.78 9.4 7.7 1.5 8.4 5.3 1.4 1 0 0 1 1 1 0 FAM176 family BTV_NS2 PF04514.7 KFP06529.1 - 0.8 8.5 7.1 1.3 7.8 4.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2722 PF10846.3 KFP06529.1 - 1.2 8.0 6.1 1.8 7.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) zf-C2H2 PF00096.21 KFP06529.1 - 1.4 9.4 6.1 7 7.2 0.1 3.4 3 0 0 3 3 2 0 Zinc finger, C2H2 type TRAP_alpha PF03896.11 KFP06529.1 - 1.9 7.4 9.8 3.2 6.6 6.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mpp10 PF04006.7 KFP06529.1 - 2.7 6.2 21.4 4.3 5.5 14.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 KFP06529.1 - 3.5 5.4 19.0 5.2 4.8 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 KFP06529.1 - 4.3 6.3 11.5 9.5 5.2 8.0 1.5 1 0 0 1 1 1 0 Myc amino-terminal region DUF605 PF04652.11 KFP06529.1 - 5.2 6.3 9.5 8.4 5.6 6.6 1.3 1 0 0 1 1 1 0 Vta1 like MH2 PF03166.9 KFP06530.1 - 1.1e-77 259.9 0.0 1.5e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFP06530.1 - 2.4e-45 152.7 4.5 4.4e-45 151.8 3.1 1.5 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFP06530.1 - 4.8e-05 23.0 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 PI3_PI4_kinase PF00454.22 KFP06531.1 - 3.2e-45 154.4 1.1 1.3e-44 152.4 0.7 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFP06531.1 - 1e-30 106.2 7.8 1.4e-30 105.8 3.2 2.5 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PX PF00787.19 KFP06531.1 - 1.6e-11 43.9 1.1 6.5e-11 42.0 0.8 2.0 1 0 0 1 1 1 1 PX domain PI3K_C2 PF00792.19 KFP06531.1 - 1.6e-10 40.8 0.2 4.5e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 KFP06531.1 - 1.7e-05 24.5 0.0 0.00027 20.7 0.0 2.5 2 0 0 2 2 2 1 C2 domain PI3K_rbd PF00794.13 KFP06531.1 - 0.032 14.1 0.2 0.14 12.1 0.0 2.2 3 0 0 3 3 3 0 PI3-kinase family, ras-binding domain PI-PLC-X PF00388.14 KFP06532.1 - 2.7e-62 208.4 0.1 4.8e-62 207.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFP06532.1 - 1.8e-43 147.2 0.1 3.6e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFP06532.1 - 1.6e-21 76.1 2.2 2e-21 75.7 0.5 1.9 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFP06532.1 - 3.2e-17 62.1 0.1 1.4e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 C2 domain 7tm_1 PF00001.16 KFP06533.1 - 1e-06 28.0 0.1 1e-06 28.0 0.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) RVT_1 PF00078.22 KFP06534.1 - 7.6e-23 80.9 0.0 8.8e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3884 PF13024.1 KFP06534.1 - 0.11 11.8 0.1 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Thiolase_N PF00108.18 KFP06535.1 - 3e-76 255.9 0.0 3.3e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KFP06535.1 - 0.014 14.8 0.4 0.025 14.0 0.3 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain zf-CSL PF05207.8 KFP06536.1 - 2.1e-17 62.3 0.4 3.3e-17 61.7 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger DUF164 PF02591.10 KFP06536.1 - 0.05 13.4 0.2 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Putative zinc ribbon domain YwqJ-deaminase PF14431.1 KFP06536.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 YwqJ-like deaminase TF_Zn_Ribbon PF08271.7 KFP06536.1 - 0.46 9.8 2.4 0.75 9.1 1.5 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding NAD_binding_1 PF00175.16 KFP06537.1 - 6.9e-13 49.1 0.0 1.5e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFP06537.1 - 5.3e-08 32.9 0.0 9.6e-07 28.8 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KFP06537.1 - 0.0045 17.0 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF1707 PF08044.6 KFP06537.1 - 0.11 12.2 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Raftlin PF15250.1 KFP06538.1 - 5.8e-192 638.2 0.7 7.1e-192 637.9 0.5 1.1 1 0 0 1 1 1 1 Raftlin DUF4177 PF13783.1 KFP06538.1 - 0.013 15.0 0.1 0.32 10.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4177) RRM_1 PF00076.17 KFP06539.1 - 1.5e-14 53.3 0.7 2.3e-14 52.7 0.5 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP06539.1 - 8.5e-13 48.0 0.2 1.3e-12 47.4 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06539.1 - 2.5e-06 27.2 0.1 5.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI-PLC-X PF00388.14 KFP06540.1 - 2.3e-59 199.0 0.1 5.2e-59 197.8 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFP06540.1 - 3.1e-43 146.5 0.3 9.6e-43 144.9 0.2 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFP06540.1 - 7.4e-26 89.9 0.1 1.8e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFP06540.1 - 8.2e-17 60.8 0.0 1.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain Mcp5_PH PF12814.2 KFP06540.1 - 3.4e-05 23.7 0.0 8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 KFP06540.1 - 0.00012 22.1 0.1 0.00051 20.2 0.0 2.1 2 0 0 2 2 2 1 PH domain RabGAP-TBC PF00566.13 KFP06541.1 - 8.6e-29 100.5 12.9 1.4e-27 96.6 8.9 2.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CUT PF02376.10 KFP06543.1 - 2e-35 120.4 10.6 8.7e-28 95.9 0.2 4.4 4 1 1 5 5 5 2 CUT domain Homeobox PF00046.24 KFP06543.1 - 5.8e-08 32.2 0.0 1.4e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain PAT1 PF09770.4 KFP06543.1 - 0.029 12.6 33.7 0.0077 14.5 8.3 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HTH_3 PF01381.17 KFP06543.1 - 0.05 13.4 0.0 0.46 10.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix RuvA_C PF07499.8 KFP06543.1 - 0.066 13.3 0.1 0.38 10.9 0.1 2.3 2 0 0 2 2 2 0 RuvA, C-terminal domain HSA PF07529.8 KFP06544.1 - 3.6e-19 68.3 13.3 3.6e-19 68.3 9.2 1.8 2 0 0 2 2 2 1 HSA DUF1336 PF07059.7 KFP06544.1 - 0.049 13.0 1.5 0.055 12.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) DUF272 PF03312.10 KFP06544.1 - 0.12 12.6 1.5 0.18 12.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF272) PX PF00787.19 KFP06544.1 - 0.14 11.9 4.0 0.091 12.5 1.1 1.9 1 1 1 2 2 2 0 PX domain CR6_interact PF10147.4 KFP06544.1 - 0.81 8.9 26.3 0.035 13.4 5.9 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DBINO PF13892.1 KFP06544.1 - 1.3 9.0 31.1 13 5.8 21.6 1.9 1 1 0 1 1 1 0 DNA-binding domain DUF619 PF04768.8 KFP06544.1 - 2.6 7.4 6.4 19 4.6 4.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF619) DUF3042 PF11240.3 KFP06544.1 - 4.7 7.0 6.1 5.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) CorA PF01544.13 KFP06544.1 - 5.5 5.9 10.5 6.7 5.6 7.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mgr1 PF08602.5 KFP06544.1 - 7.3 5.4 8.6 8.3 5.3 6.0 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit RNase_PH PF01138.16 KFP06545.1 - 5e-16 59.2 0.1 3.5e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFP06545.1 - 2.7e-07 30.4 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-C3HC4 PF00097.20 KFP06546.1 - 6.6e-11 41.6 10.3 1e-10 41.0 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP06546.1 - 4.1e-09 36.1 8.5 6.7e-09 35.4 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP06546.1 - 2.4e-08 33.8 9.4 3.6e-08 33.2 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP06546.1 - 1e-06 28.3 8.5 1.5e-06 27.7 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP06546.1 - 1.1e-05 25.0 8.9 1.8e-05 24.3 6.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP06546.1 - 2.7e-05 23.9 8.4 4.7e-05 23.1 5.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KFP06546.1 - 3e-05 23.4 5.8 4.5e-05 22.8 4.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KFP06546.1 - 0.0002 20.8 7.0 0.0004 19.9 4.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KFP06546.1 - 0.00062 19.4 4.0 0.001 18.8 2.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFP06546.1 - 0.0033 17.1 5.0 0.0074 15.9 3.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KFP06546.1 - 0.0073 15.8 7.4 0.012 15.1 5.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-UDP PF14569.1 KFP06546.1 - 0.023 14.4 1.0 0.047 13.4 0.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-rbx1 PF12678.2 KFP06546.1 - 0.038 14.1 5.5 0.1 12.7 3.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFP06546.1 - 0.13 12.0 2.5 0.26 11.1 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_4 PF13894.1 KFP06546.1 - 0.25 11.7 1.7 8.8 6.9 0.1 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C4_Topoisom PF01396.14 KFP06546.1 - 0.38 10.2 3.7 0.15 11.6 0.5 1.8 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DZR PF12773.2 KFP06546.1 - 1.7 8.5 6.6 19 5.1 4.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon DUF329 PF03884.9 KFP06546.1 - 4.6 6.8 6.9 2.5 7.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-C4H2 PF10146.4 KFP06548.1 - 5.4e-87 291.6 22.2 6.1e-87 291.4 15.4 1.0 1 0 0 1 1 1 1 Zinc finger-containing protein Sec20 PF03908.8 KFP06548.1 - 0.0082 15.8 4.3 0.012 15.2 0.1 2.3 1 1 1 2 2 2 1 Sec20 DZR PF12773.2 KFP06548.1 - 0.011 15.4 1.6 0.024 14.4 1.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon BLOC1_2 PF10046.4 KFP06548.1 - 0.035 14.2 8.4 1.5 8.9 0.2 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lipoprotein_7 PF01540.11 KFP06548.1 - 0.042 12.9 4.6 0.072 12.1 3.2 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein zf-P11 PF03854.9 KFP06548.1 - 0.075 12.5 2.3 0.15 11.5 1.6 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_3 PF13920.1 KFP06548.1 - 0.092 12.4 4.2 0.16 11.6 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KFP06548.1 - 0.11 12.1 2.8 0.21 11.1 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Polysacc_synt_4 PF04669.8 KFP06548.1 - 0.25 10.7 2.7 0.4 10.0 1.9 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis DUF4041 PF13250.1 KFP06548.1 - 0.37 10.3 2.4 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Spc7 PF08317.6 KFP06548.1 - 0.49 9.0 13.1 0.63 8.6 9.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.13 KFP06548.1 - 0.6 9.8 12.3 2.6 7.8 2.6 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.7 KFP06548.1 - 0.93 9.3 5.4 1.6 8.5 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_IE-1 PF05290.6 KFP06548.1 - 1.1 8.9 4.4 5.8 6.6 0.3 2.5 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) TMF_TATA_bd PF12325.3 KFP06548.1 - 1.3 8.7 19.9 3.6 7.3 1.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Tup_N PF08581.5 KFP06548.1 - 1.8 8.7 12.9 0.94 9.7 5.2 2.7 1 1 1 2 2 2 0 Tup N-terminal DUF3450 PF11932.3 KFP06548.1 - 2 7.5 17.4 0.15 11.3 2.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) WAC_Acf1_DNA_bd PF10537.4 KFP06548.1 - 2.5 8.3 5.4 5.5 7.2 0.8 2.4 1 1 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF972 PF06156.8 KFP06548.1 - 3.1 8.1 16.9 4.8 7.5 3.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KFP06548.1 - 7.3 4.9 14.3 0.18 10.2 5.1 1.7 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 KFP06548.1 - 8.8 5.8 21.2 24 4.4 14.7 1.8 1 1 0 1 1 1 0 IncA protein RNase_Zc3h12a PF11977.3 KFP06549.1 - 6.5e-64 214.4 0.0 9.1e-64 213.9 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 PF14608.1 KFP06549.1 - 0.63 10.1 10.0 1.1 9.3 6.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Omega-toxin PF06357.6 KFP06549.1 - 0.73 9.4 7.8 0.069 12.7 2.1 1.7 2 0 0 2 2 2 0 Omega-atracotoxin zf-CCCH PF00642.19 KFP06549.1 - 1 9.1 7.7 2.5 7.8 3.9 2.2 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Las1 PF04031.8 KFP06551.1 - 1.3e-45 154.7 0.0 1.6e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Las1-like ERM PF00769.14 KFP06552.1 - 1.1e-72 244.5 70.1 1.1e-72 244.5 48.6 2.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family FERM_C PF09380.5 KFP06552.1 - 4.8e-33 113.2 0.0 1.7e-32 111.4 0.0 2.0 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFP06552.1 - 8.6e-26 90.5 0.6 8.6e-26 90.5 0.4 4.0 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.5 KFP06552.1 - 5.4e-19 68.0 0.2 5.4e-19 68.0 0.1 3.2 3 0 0 3 3 3 1 FERM N-terminal domain Fer2 PF00111.22 KFP06553.1 - 4.1e-08 32.8 0.7 5.7e-08 32.3 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RE_NgoPII PF09521.5 KFP06553.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 NgoPII restriction endonuclease DUF3856 PF12968.2 KFP06553.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) RhoGAP PF00620.22 KFP06554.1 - 1.6e-35 121.9 0.0 1.5e-34 118.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KFP06554.1 - 8e-07 29.2 0.5 2.2e-06 27.7 0.1 1.9 2 0 0 2 2 2 1 PH domain RA PF00788.18 KFP06554.1 - 2.2e-05 24.8 0.0 6.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFP06554.1 - 0.00018 21.3 0.0 0.00062 19.6 0.0 1.9 1 0 0 1 1 1 1 Ras-binding domain of Byr2 DUF2183 PF09949.4 KFP06554.1 - 0.15 12.0 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) V-set PF07686.12 KFP06555.1 - 3.8e-16 58.9 0.1 4.6e-09 36.1 0.0 3.1 2 1 1 3 3 3 2 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP06555.1 - 1.2e-13 51.0 0.0 3.1e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP06555.1 - 4.1e-11 43.2 0.1 2.7e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.11 KFP06555.1 - 3.8e-09 36.2 0.0 0.002 17.9 0.0 3.0 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFP06555.1 - 7e-09 35.6 1.2 0.0019 18.2 0.1 3.9 2 2 1 3 3 3 2 Immunoglobulin domain V-set_CD47 PF08204.6 KFP06555.1 - 0.034 13.9 0.0 0.071 12.8 0.0 1.5 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain V-set PF07686.12 KFP06556.1 - 1.7e-13 50.4 0.0 1e-07 31.8 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFP06556.1 - 5.6e-09 35.7 0.0 0.00019 21.2 0.0 2.5 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP06556.1 - 6e-08 32.7 0.0 0.0025 17.8 0.0 2.5 2 2 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP06556.1 - 8.4e-07 29.0 0.0 0.0052 16.8 0.0 2.9 3 0 0 3 3 3 2 Immunoglobulin domain Ig_3 PF13927.1 KFP06556.1 - 9.9e-07 29.1 0.1 0.073 13.5 0.0 2.8 3 1 0 3 3 3 2 Immunoglobulin domain HSF_DNA-bind PF00447.12 KFP06557.1 - 3.2e-26 91.5 1.3 6.5e-26 90.5 0.9 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Vert_HS_TF PF06546.6 KFP06557.1 - 1.4e-18 67.2 4.2 2.2e-18 66.5 2.9 1.3 1 0 0 1 1 1 1 Vertebrate heat shock transcription factor Nnf1 PF03980.9 KFP06557.1 - 0.015 15.2 0.8 0.039 13.9 0.6 1.7 1 0 0 1 1 1 0 Nnf1 TBPIP PF07106.8 KFP06557.1 - 0.076 12.5 4.9 0.028 13.9 1.6 1.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Muted PF14942.1 KFP06557.1 - 0.11 12.4 4.5 0.24 11.2 3.1 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Phage_GPO PF05929.6 KFP06557.1 - 0.17 11.1 1.4 0.31 10.2 1.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Cu-oxidase_2 PF07731.9 KFP06558.1 - 7.6e-29 99.9 14.4 1.7e-11 43.7 0.7 6.0 5 1 0 5 5 5 5 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFP06558.1 - 1.6e-24 85.9 2.3 1.5e-07 31.1 0.0 5.3 5 0 0 5 5 5 3 Multicopper oxidase 7tm_1 PF00001.16 KFP06559.1 - 5.9e-59 199.2 28.8 3e-58 196.9 20.6 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06559.1 - 2e-14 53.3 27.9 2.6e-14 53.0 19.4 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2109 PF09882.4 KFP06559.1 - 0.97 9.4 8.5 0.5 10.3 2.2 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) 7tm_1 PF00001.16 KFP06560.1 - 1.9e-58 197.6 23.3 2.9e-58 197.0 16.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06560.1 - 3.6e-16 59.1 21.7 4.5e-16 58.7 15.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx PhaC_N PF07167.8 KFP06560.1 - 0.098 12.0 0.1 9.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DUF2109 PF09882.4 KFP06560.1 - 1.7 8.6 10.4 0.18 11.7 1.8 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2109) TNFR_c6 PF00020.13 KFP06561.1 - 4.3e-11 42.6 31.9 1.6e-06 28.0 4.2 3.8 4 1 0 4 4 4 2 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFP06561.1 - 0.0061 16.1 25.3 0.0091 15.5 2.4 3.4 2 1 1 3 3 3 2 GCC2 and GCC3 NCD3G PF07562.9 KFP06561.1 - 0.14 11.8 21.3 0.75 9.5 2.5 3.8 2 1 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR UPF0560 PF10577.4 KFP06561.1 - 0.15 10.2 0.2 0.2 9.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hormone_recep PF00104.25 KFP06562.1 - 1.8e-31 108.8 2.7 2.8e-31 108.2 1.9 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP06562.1 - 3.4e-25 88.0 14.2 6.3e-25 87.1 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) RhoGAP PF00620.22 KFP06563.1 - 2.8e-41 140.6 0.1 9e-41 139.0 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain Patched PF02460.13 KFP06563.1 - 1.6 6.5 3.6 2.1 6.1 2.5 1.2 1 0 0 1 1 1 0 Patched family YlqD PF11068.3 KFP06563.1 - 4.1 7.4 7.9 1.7 8.6 2.2 2.4 2 0 0 2 2 2 0 YlqD protein Yip1 PF04893.12 KFP06564.1 - 2.7e-18 66.0 12.8 2.7e-18 66.0 8.9 1.7 1 1 1 2 2 2 1 Yip1 domain RhoGAP PF00620.22 KFP06565.1 - 2.7e-39 134.1 0.2 5.4e-39 133.2 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain START PF01852.14 KFP06565.1 - 3.9e-37 127.5 0.0 8.8e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 START domain SAM_2 PF07647.12 KFP06565.1 - 0.027 14.3 0.0 0.077 12.8 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LRR_8 PF13855.1 KFP06566.1 - 1.7e-44 149.3 24.0 2e-14 53.0 1.0 5.4 1 1 4 5 5 5 5 Leucine rich repeat 7tm_1 PF00001.16 KFP06566.1 - 1e-25 90.3 7.5 1.5e-25 89.7 5.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LRR_4 PF12799.2 KFP06566.1 - 4.3e-24 83.6 24.5 2.9e-06 26.7 2.1 6.3 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP06566.1 - 6.9e-18 64.6 0.0 1.5e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP06566.1 - 7.3e-11 40.5 23.8 0.082 12.9 0.0 10.3 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_9 PF14580.1 KFP06566.1 - 2.9e-09 36.7 1.5 7.4e-06 25.6 0.2 3.1 1 1 2 3 3 3 3 Leucine-rich repeat Ldl_recept_a PF00057.13 KFP06566.1 - 7e-09 35.4 5.5 7e-09 35.4 3.8 1.9 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A LRR_6 PF13516.1 KFP06566.1 - 1.1e-05 24.9 9.5 3 8.1 0.1 7.7 7 2 1 8 8 8 1 Leucine Rich repeat LRRNT PF01462.13 KFP06566.1 - 0.00017 20.9 0.5 0.00045 19.6 0.3 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFP06566.1 - 0.0012 18.7 25.1 2.2 8.8 0.0 9.4 10 1 0 10 10 10 2 Leucine rich repeat Ephrin PF00812.12 KFP06567.1 - 2.2e-45 153.7 2.1 2.6e-45 153.5 0.1 1.9 2 0 0 2 2 2 1 Ephrin DUF4381 PF14316.1 KFP06567.1 - 0.002 18.2 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Herpes_gE PF02480.11 KFP06567.1 - 0.005 15.1 0.1 0.0089 14.3 0.0 1.4 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Baculo_11_kDa PF06143.6 KFP06567.1 - 0.0087 15.4 0.7 0.016 14.5 0.5 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family Shisa PF13908.1 KFP06567.1 - 0.027 14.6 0.2 0.079 13.1 0.0 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator P12 PF12669.2 KFP06567.1 - 0.036 14.2 0.2 0.079 13.1 0.1 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family Orthoreo_P10 PF07204.6 KFP06567.1 - 0.038 13.7 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Cytomega_TRL10 PF06084.6 KFP06567.1 - 0.054 13.3 0.2 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Protocadherin PF08374.6 KFP06567.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DUF912 PF06024.7 KFP06567.1 - 0.091 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1517 PF07466.6 KFP06567.1 - 0.093 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) PalH PF08733.5 KFP06567.1 - 0.1 11.4 0.0 0.32 9.7 0.0 1.6 2 0 0 2 2 2 0 PalH/RIM21 EphA2_TM PF14575.1 KFP06567.1 - 0.12 12.7 0.3 0.25 11.7 0.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MSC PF09402.5 KFP06567.1 - 0.13 10.9 0.2 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Syndecan PF01034.15 KFP06567.1 - 0.15 11.7 2.6 0.25 11.0 1.8 1.3 1 0 0 1 1 1 0 Syndecan domain WSS_VP PF12175.3 KFP06567.1 - 0.18 10.8 0.7 0.29 10.1 0.5 1.3 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Yae1_N PF09811.4 KFP06568.1 - 2.3e-15 55.8 44.2 1.5e+04 -4.7 30.6 4.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal TNF PF00229.13 KFP06569.1 - 1.3e-17 63.5 0.1 1.8e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Collagen PF01391.13 KFP06569.1 - 1e-07 31.3 45.1 5.4e-05 22.6 31.2 2.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) LRR_8 PF13855.1 KFP06570.1 - 1.1e-55 185.1 53.8 1.2e-11 44.2 0.8 10.5 5 3 5 11 11 11 10 Leucine rich repeat LRR_4 PF12799.2 KFP06570.1 - 1.2e-44 149.2 54.8 3.3e-06 26.6 1.8 11.4 9 2 2 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP06570.1 - 4.7e-31 102.0 61.8 0.17 11.9 0.0 19.9 16 4 4 20 20 20 13 Leucine Rich Repeat LRR_7 PF13504.1 KFP06570.1 - 2.5e-11 41.8 81.2 1.6 9.2 0.0 19.8 18 3 3 21 21 21 8 Leucine rich repeat LRR_6 PF13516.1 KFP06570.1 - 8.8e-09 34.5 68.5 2.8 8.2 0.4 18.1 18 1 1 19 19 19 5 Leucine Rich repeat LRR_5 PF13306.1 KFP06570.1 - 4.7e-05 23.0 0.0 0.4 10.3 0.0 3.3 4 0 0 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 KFP06570.1 - 0.0094 15.5 1.1 0.87 9.1 0.0 3.5 2 1 1 3 3 3 1 Leucine-rich repeat LRRNT PF01462.13 KFP06570.1 - 0.046 13.2 0.3 0.14 11.6 0.2 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain FNIP PF05725.7 KFP06570.1 - 8.9 6.3 11.2 4.1 7.4 0.2 4.5 7 0 0 7 7 7 0 FNIP Repeat wnt PF00110.14 KFP06571.1 - 2.9e-105 351.8 10.5 3.3e-105 351.6 7.3 1.0 1 0 0 1 1 1 1 wnt family TAP42 PF04177.7 KFP06572.1 - 4.1e-75 252.8 0.2 1.1e-74 251.4 0.1 1.6 1 1 0 1 1 1 1 TAP42-like family Ribosomal_60s PF00428.14 KFP06572.1 - 0.025 14.9 0.3 2.1 8.7 0.0 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein DAGAT PF03982.8 KFP06573.1 - 2.9e-116 387.3 0.0 4.3e-116 386.7 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Ras PF00071.17 KFP06574.1 - 1.6e-55 186.9 0.4 2e-55 186.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06574.1 - 1.4e-17 64.3 0.1 3.4e-17 63.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFP06574.1 - 1.2e-12 47.3 0.5 1.4e-12 47.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP06574.1 - 2.6e-07 30.2 0.1 4.3e-07 29.5 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP06574.1 - 0.00091 18.4 0.1 0.0013 17.9 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFP06574.1 - 0.0079 15.4 0.1 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 KFP06574.1 - 0.037 13.1 0.2 0.045 12.8 0.2 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PDZ PF00595.19 KFP06575.1 - 6.9e-18 64.6 0.2 7.8e-18 64.4 0.1 1.0 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP06575.1 - 2.6e-08 33.6 0.0 2.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Kinesin PF00225.18 KFP06576.1 - 2.2e-115 384.9 0.0 2.2e-115 384.9 0.0 3.0 4 1 1 5 5 5 1 Kinesin motor domain TFIID-31kDa PF02291.10 KFP06577.1 - 6.5e-55 184.4 0.1 9.1e-55 183.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 KFP06577.1 - 9.1e-07 28.9 0.1 1.6e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KFP06577.1 - 6.8e-06 25.7 0.1 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KFP06577.1 - 0.00033 20.7 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_30kDa PF03540.8 KFP06577.1 - 0.046 13.5 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit 7tm_1 PF00001.16 KFP06579.1 - 1.3e-43 149.0 25.6 1.6e-43 148.7 17.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP06579.1 - 1.8e-07 30.5 22.9 2.5e-07 30.1 15.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx Git3 PF11710.3 KFP06579.1 - 5 6.6 24.9 2.5 7.5 10.9 2.2 1 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 HMG_box_2 PF09011.5 KFP06580.1 - 1.8e-50 169.1 11.1 7e-30 103.2 5.5 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KFP06580.1 - 1.3e-45 153.5 10.1 1.4e-27 95.6 0.1 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.1 KFP06580.1 - 6.3e-05 22.6 11.0 0.018 14.8 1.9 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Nucleoplasmin PF03066.10 KFP06580.1 - 0.36 10.3 11.0 0.64 9.5 7.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin YABBY PF04690.8 KFP06580.1 - 0.84 9.8 4.2 0.3 11.2 0.4 2.1 2 1 1 3 3 3 0 YABBY protein CD99L2 PF12301.3 KFP06581.1 - 4.9e-46 156.4 2.0 5.8e-46 156.2 1.4 1.0 1 0 0 1 1 1 1 CD99 antigen like protein 2 ACT_7 PF13840.1 KFP06581.1 - 0.13 11.7 1.6 0.13 11.7 0.3 1.6 2 0 0 2 2 2 0 ACT domain Myotub-related PF06602.9 KFP06582.1 - 1.1e-146 488.1 0.0 1.4e-146 487.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 KFP06582.1 - 4.3e-08 32.5 0.0 9.1e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 KFP06582.1 - 0.00017 21.0 0.0 0.00037 19.9 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFP06582.1 - 0.00035 20.8 0.0 0.0007 19.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 KFP06582.1 - 0.00065 19.2 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4441 PF14536.1 KFP06582.1 - 0.056 13.4 1.1 0.13 12.2 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Myotub-related PF06602.9 KFP06583.1 - 1e-146 488.2 0.1 1.5e-146 487.7 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 KFP06583.1 - 6e-13 48.1 0.0 1.4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 KFP06583.1 - 0.00025 20.4 0.0 0.00054 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP06583.1 - 0.00045 19.8 0.0 0.00092 18.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP06583.1 - 0.0035 17.6 0.1 0.0084 16.3 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family 3-PAP PF12578.3 KFP06583.1 - 0.019 14.7 0.9 0.053 13.3 0.5 1.9 1 1 0 1 1 1 0 Myotubularin-associated protein ASCH PF04266.9 KFP06584.1 - 0.038 14.3 0.0 0.045 14.1 0.0 1.3 1 1 0 1 1 1 0 ASCH domain Tmemb_185A PF10269.4 KFP06585.1 - 1.3e-69 234.4 27.2 1.3e-69 234.4 18.8 1.4 2 0 0 2 2 2 1 Transmembrane Fragile-X-F protein Sulfatase PF00884.18 KFP06586.1 - 2e-51 174.9 0.1 2.9e-51 174.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFP06586.1 - 4.8e-10 39.2 0.1 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFP06586.1 - 0.0011 17.5 0.0 0.01 14.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF229) AF-4 PF05110.8 KFP06587.1 - 2.5e-177 592.1 81.7 2.7e-177 591.9 56.6 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein ADAM_spacer1 PF05986.9 KFP06589.1 - 8.1e-33 112.6 0.1 1.3e-32 111.9 0.1 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFP06589.1 - 2.8e-29 102.1 0.4 4.3e-29 101.5 0.3 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.1 KFP06589.1 - 8.1e-16 58.5 1.9 8.1e-16 58.5 1.3 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFP06589.1 - 1.8e-11 44.6 0.2 1.8e-11 44.6 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP06589.1 - 2.5e-10 40.2 0.7 5e-10 39.2 0.2 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP06589.1 - 2.8e-10 40.5 1.2 5.7e-10 39.5 0.9 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.14 KFP06589.1 - 3e-07 30.4 7.5 3e-07 30.4 5.2 7.0 7 1 0 7 7 7 3 Thrombospondin type 1 domain DUF955 PF06114.8 KFP06589.1 - 0.02 14.6 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Pep_M12B_propep PF01562.14 KFP06589.1 - 0.05 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Reprolysin family propeptide Yae1_N PF09811.4 KFP06590.1 - 1.7e-18 65.8 57.0 1.5e+04 -17.6 39.5 5.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal RRM_1 PF00076.17 KFP06591.1 - 3.5e-12 45.7 0.0 6.2e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP06591.1 - 2e-08 34.0 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06591.1 - 8.1e-08 32.0 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4611 PF15387.1 KFP06591.1 - 0.0025 17.9 1.0 0.0042 17.1 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) RP-C_C PF11800.3 KFP06591.1 - 0.12 12.0 1.5 0.18 11.4 1.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region eIF-5_eIF-2B PF01873.12 KFP06592.1 - 5.5e-49 164.9 1.9 9.3e-49 164.2 1.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Maf1 PF09174.5 KFP06593.1 - 1.5e-66 223.6 0.0 2e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator zf-RanBP PF00641.13 KFP06594.1 - 4.1e-08 32.1 1.7 7.1e-08 31.4 1.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PHD PF00628.24 KFP06594.1 - 0.34 10.6 2.8 0.55 9.9 0.3 2.3 2 0 0 2 2 2 0 PHD-finger Cytochrom_C1 PF02167.10 KFP06595.1 - 6.9e-83 277.6 0.0 8e-83 277.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KFP06595.1 - 0.0026 17.8 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KFP06595.1 - 0.0084 16.9 0.0 0.019 15.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome c Gaa1 PF04114.9 KFP06596.1 - 1.7e-155 518.5 0.1 2.3e-155 518.1 0.1 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component FH2 PF02181.18 KFP06597.1 - 2.1e-90 303.2 12.8 2.5e-90 303.0 8.9 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain CPDase PF07823.6 KFP06597.1 - 0.021 14.3 0.7 0.069 12.6 0.3 1.9 1 1 1 2 2 2 0 Cyclic phosphodiesterase-like protein DUF1539 PF07560.6 KFP06597.1 - 0.042 13.7 1.0 0.1 12.4 0.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Arch_fla_DE PF04659.8 KFP06597.1 - 0.052 13.3 0.9 0.31 10.8 0.5 2.3 2 0 0 2 2 2 0 Archaeal flagella protein FF PF01846.14 KFP06598.1 - 5.7e-46 154.2 25.1 1.4e-15 56.9 0.4 6.6 6 0 0 6 6 6 5 FF domain WW PF00397.21 KFP06598.1 - 1.1e-18 66.7 19.1 1.4e-09 37.6 5.7 2.7 2 0 0 2 2 2 2 WW domain TPR_6 PF13174.1 KFP06598.1 - 7.6 7.2 7.5 14 6.3 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF162 PF02589.10 KFP06598.1 - 7.7 5.9 8.4 1.4 8.3 0.5 2.7 3 0 0 3 3 3 0 Uncharacterised ACR, YkgG family COG1556 Glycos_transf_2 PF00535.21 KFP06599.1 - 1.4e-33 116.0 0.0 2.3e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP06599.1 - 1.7e-27 95.9 0.8 2.6e-27 95.2 0.5 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFP06599.1 - 7.7e-12 45.4 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFP06599.1 - 2.8e-07 29.9 0.1 5.8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP06599.1 - 1.3e-05 24.4 0.0 7.4e-05 21.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFP06599.1 - 0.0042 17.4 0.0 0.99 9.8 0.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like IRK PF01007.15 KFP06600.1 - 5.6e-161 534.9 0.1 6.2e-161 534.8 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel DUF3311 PF11755.3 KFP06600.1 - 0.0083 15.6 2.1 0.016 14.7 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) Ion_trans_2 PF07885.11 KFP06600.1 - 0.21 11.2 10.8 1 9.0 7.5 2.1 1 1 0 1 1 1 0 Ion channel DAO PF01266.19 KFP06601.1 - 8.2e-50 169.6 0.0 1.1e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 KFP06601.1 - 3.4e-11 43.1 0.7 8.1e-11 41.9 0.5 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP06601.1 - 4.6e-10 38.0 0.4 0.0003 19.8 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP06601.1 - 5.2e-09 35.2 0.2 8.2e-05 22.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain FAD_oxidored PF12831.2 KFP06601.1 - 1.9e-08 33.8 0.1 1.7e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFP06601.1 - 3.9e-08 32.5 0.1 2.7e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KFP06601.1 - 5.8e-06 25.4 0.0 0.0016 17.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KFP06601.1 - 6.2e-05 22.9 0.1 0.0021 17.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 KFP06601.1 - 0.00015 21.2 0.6 0.00055 19.4 0.2 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP06601.1 - 0.0003 19.9 0.6 0.77 9.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 KFP06601.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain HI0933_like PF03486.9 KFP06601.1 - 0.0032 16.0 0.0 0.005 15.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KFP06601.1 - 0.012 15.6 0.6 0.043 13.8 0.1 2.3 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFP06601.1 - 0.019 14.0 0.0 0.049 12.7 0.0 1.7 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KFP06601.1 - 0.032 14.6 1.0 0.25 11.7 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFP06601.1 - 0.041 12.9 0.1 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain CENP-T PF15511.1 KFP06602.1 - 0.025 13.8 16.0 0.032 13.4 11.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Myc_N PF01056.13 KFP06602.1 - 0.038 13.1 14.3 0.021 13.9 8.9 1.3 1 1 0 1 1 1 0 Myc amino-terminal region BUD22 PF09073.5 KFP06602.1 - 1.1 8.2 13.4 1.2 8.1 9.3 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KFP06602.1 - 1.9 6.3 15.0 2.1 6.1 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 KFP06602.1 - 2.6 8.0 15.8 1 9.3 6.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) PBP1_TM PF14812.1 KFP06602.1 - 3.1 8.1 7.5 1.4 9.2 3.5 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 KFP06602.1 - 4 5.3 8.1 5 5.0 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PDZ PF00595.19 KFP06603.1 - 2.2e-09 37.3 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP06603.1 - 8.8e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Pkinase PF00069.20 KFP06604.1 - 1.6e-52 178.2 0.0 2.5e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06604.1 - 1.9e-33 115.6 0.0 2.7e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFP06604.1 - 1.3e-17 62.7 0.3 3.3e-17 61.4 0.2 1.8 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFP06604.1 - 1.5e-11 44.7 14.3 1.5e-11 44.7 9.9 2.0 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 KFP06604.1 - 0.025 14.3 0.0 0.064 12.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KFP06605.1 - 2.4e-62 210.4 0.0 3.4e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06605.1 - 1.6e-36 125.7 0.0 2.3e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFP06605.1 - 1.3e-16 59.5 0.4 2.6e-16 58.6 0.3 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFP06605.1 - 1.7e-09 38.1 12.6 5e-09 36.6 8.7 1.9 1 0 0 1 1 1 1 Activin types I and II receptor domain APH PF01636.18 KFP06605.1 - 0.0037 17.0 0.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family TMEM154 PF15102.1 KFP06605.1 - 0.0041 16.8 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family Choline_kinase PF01633.15 KFP06605.1 - 0.18 11.3 0.5 13 5.2 0.1 3.0 2 1 1 4 4 4 0 Choline/ethanolamine kinase DUF4083 PF13314.1 KFP06605.1 - 0.22 11.3 1.4 0.45 10.3 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Arm PF00514.18 KFP06607.1 - 2.8e-40 134.7 17.3 1.1e-09 37.7 0.0 9.2 10 0 0 10 10 10 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP06607.1 - 1.7e-09 37.8 1.5 0.00033 20.8 0.0 3.7 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KFP06607.1 - 2.5e-07 30.1 4.0 0.96 9.7 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KFP06607.1 - 0.018 15.5 1.9 9.6 6.8 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat DAP PF15228.1 KFP06608.1 - 1.1e-11 45.2 1.0 1.3e-11 45.0 0.7 1.0 1 0 0 1 1 1 1 Death-associated protein Ank_2 PF12796.2 KFP06609.1 - 2.2e-84 277.9 17.5 6.9e-24 84.0 0.0 5.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFP06609.1 - 2.6e-56 184.7 9.1 8.2e-08 31.6 0.0 11.4 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 KFP06609.1 - 1.3e-46 156.1 6.5 8.1e-10 38.9 0.0 8.3 2 2 7 9 9 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP06609.1 - 1.3e-38 127.0 3.4 0.00075 19.5 0.0 10.8 11 0 0 11 11 10 6 Ankyrin repeat Ank_5 PF13857.1 KFP06609.1 - 1.1e-37 127.2 4.3 8.6e-11 41.7 0.0 7.4 2 2 5 7 7 7 7 Ankyrin repeats (many copies) TPR_11 PF13414.1 KFP06609.1 - 3e-10 39.5 8.0 6.6e-07 28.8 2.6 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFP06609.1 - 1.3e-07 31.0 7.0 0.25 11.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFP06609.1 - 4.4e-05 23.2 1.8 0.006 16.4 0.7 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP06609.1 - 0.0015 18.0 6.1 3.4 7.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP06609.1 - 0.0021 18.7 8.0 0.022 15.4 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP06609.1 - 0.0061 16.2 0.5 0.18 11.6 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP06609.1 - 0.01 16.1 3.7 0.87 9.9 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFP06609.1 - 0.017 15.0 3.1 0.025 14.5 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFP06609.1 - 0.018 15.6 4.3 0.15 12.7 1.7 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFP06609.1 - 0.023 14.8 1.5 0.26 11.5 0.5 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFP06609.1 - 0.089 12.6 0.2 8.7 6.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RP-C_C PF11800.3 KFP06609.1 - 3.6 7.2 9.8 0.11 12.1 2.1 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region WD40 PF00400.27 KFP06610.1 - 8.7e-64 209.3 25.7 2.8e-12 45.9 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat U-box PF04564.10 KFP06610.1 - 4.5e-27 93.8 0.2 1.1e-26 92.6 0.1 1.7 1 0 0 1 1 1 1 U-box domain SAM_2 PF07647.12 KFP06610.1 - 5.1e-13 48.6 0.2 8.7e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP06610.1 - 1.3e-09 38.1 0.1 2.2e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) eIF2A PF08662.6 KFP06610.1 - 3.5e-06 26.8 0.0 0.036 13.7 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KFP06610.1 - 7.4e-06 24.4 0.0 0.039 12.2 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3312) SAM_PNT PF02198.11 KFP06610.1 - 5.1e-05 22.9 0.0 0.00019 21.1 0.0 1.9 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain zf-Nse PF11789.3 KFP06610.1 - 0.00057 19.3 0.0 0.0017 17.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Bromodomain PF00439.20 KFP06611.1 - 4.8e-24 84.0 0.0 2.4e-23 81.8 0.0 2.3 1 0 0 1 1 1 1 Bromodomain DDT PF02791.12 KFP06611.1 - 2.9e-14 52.5 0.1 6.1e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 DDT domain MBD PF01429.14 KFP06611.1 - 1.5e-13 50.0 0.2 4.1e-13 48.6 0.1 1.7 1 0 0 1 1 1 1 Methyl-CpG binding domain PHD PF00628.24 KFP06611.1 - 1.8e-11 43.5 9.3 5.1e-11 42.0 6.4 1.8 1 0 0 1 1 1 1 PHD-finger WHIM2 PF15613.1 KFP06611.1 - 0.011 15.5 0.3 0.032 14.1 0.2 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Daxx PF03344.10 KFP06611.1 - 0.23 9.9 117.9 0.0022 16.5 21.6 4.4 4 0 0 4 4 4 0 Daxx Family RINGv PF12906.2 KFP06612.1 - 6.8e-15 54.8 8.1 1.5e-14 53.7 5.6 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KFP06612.1 - 0.0002 21.2 4.0 0.0002 21.2 2.8 1.8 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KFP06612.1 - 0.0012 18.6 4.9 0.0027 17.5 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP06612.1 - 0.3 11.2 2.1 0.68 10.0 1.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger LRR_8 PF13855.1 KFP06613.1 - 1.1e-21 76.3 42.9 1.8e-08 34.0 3.3 3.8 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 KFP06613.1 - 3.8e-17 61.4 24.3 5.7e-07 29.0 0.8 4.4 2 2 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFP06613.1 - 8.4e-09 35.2 4.5 1.3e-08 34.6 2.5 1.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 KFP06613.1 - 2.9e-06 26.5 18.6 0.82 9.9 0.1 6.5 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 KFP06613.1 - 3e-05 23.6 17.9 0.025 14.6 0.3 6.1 5 2 1 6 6 6 4 Leucine Rich repeat LRR_7 PF13504.1 KFP06613.1 - 0.0025 17.7 15.7 8.8 7.0 0.0 6.7 5 2 1 6 6 6 1 Leucine rich repeat adh_short PF00106.20 KFP06614.1 - 1.9e-25 89.7 0.0 2.5e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFP06614.1 - 1.3e-10 41.4 0.1 1.8e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFP06614.1 - 7.8e-06 25.6 0.0 1.6e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KFP06614.1 - 0.00024 20.0 0.0 0.00096 18.1 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KFP06614.1 - 0.00027 20.9 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFP06614.1 - 0.0076 15.2 0.0 0.015 14.3 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KFP06614.1 - 0.02 14.3 0.6 0.15 11.4 0.4 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 KFP06614.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Peptidase_S8 PF00082.17 KFP06615.1 - 3.4e-43 147.8 0.0 4.8e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family ABM PF03992.11 KFP06616.1 - 1.9e-08 34.1 0.2 5.8e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase EF-hand_8 PF13833.1 KFP06616.1 - 2.7e-06 26.8 2.4 2.5e-05 23.8 1.6 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP06616.1 - 1.7e-05 23.7 1.6 0.025 13.8 0.1 2.8 1 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP06616.1 - 4.8e-05 22.8 1.4 0.06 13.2 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KFP06616.1 - 8.1e-05 22.6 2.3 0.00023 21.2 1.6 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP06616.1 - 0.0011 18.2 4.0 0.15 11.4 0.0 3.3 1 1 2 3 3 3 2 EF hand SICA_beta PF12878.2 KFP06616.1 - 0.057 13.2 0.1 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 SICA extracellular beta domain FAM92 PF06730.6 KFP06616.1 - 0.057 12.7 0.1 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 FAM92 protein RVT_1 PF00078.22 KFP06617.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_3 PF13738.1 KFP06618.1 - 3.3e-11 43.6 0.0 5.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFP06618.1 - 3.8e-05 23.6 0.0 0.00015 21.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.1 KFP06619.1 - 7.4e-68 229.0 41.5 9e-68 228.7 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFP06619.1 - 3.1e-26 91.7 32.1 3.1e-26 91.7 22.2 1.3 1 1 0 1 1 1 1 Amino acid permease DUF1762 PF08574.5 KFP06620.1 - 5.1e-07 30.0 16.7 5.1e-07 30.0 11.6 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF1762) Exo_endo_phos PF03372.18 KFP06621.1 - 2.1e-08 34.4 0.0 3.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SCPU PF05229.10 KFP06621.1 - 0.014 15.5 0.5 0.9 9.6 0.0 2.5 2 0 0 2 2 2 0 Spore Coat Protein U domain CBM_6 PF03422.10 KFP06621.1 - 0.037 14.1 0.1 0.09 12.9 0.1 1.7 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) LCAT PF02450.10 KFP06622.1 - 9.4e-84 281.6 0.6 1.2e-83 281.3 0.4 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 KFP06622.1 - 6.4e-06 25.4 0.7 0.025 13.6 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 KFP06622.1 - 0.00056 19.8 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFP06622.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 KFP06622.1 - 0.045 13.0 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 KFP06622.1 - 0.089 12.5 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family RRM_6 PF14259.1 KFP06623.1 - 3.4e-50 167.9 0.0 7e-17 61.1 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP06623.1 - 8.4e-15 54.1 0.0 0.0026 17.3 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06623.1 - 0.00026 20.7 0.3 2.8 7.8 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KFP06623.1 - 0.0084 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DUF4283 PF14111.1 KFP06623.1 - 0.065 12.3 0.0 30 3.6 0.0 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4283) CedA PF10729.4 KFP06623.1 - 0.089 12.3 0.0 6.2 6.4 0.0 3.1 3 0 0 3 3 3 0 Cell division activator CedA DUF4049 PF13258.1 KFP06623.1 - 0.17 10.8 0.0 0.42 9.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) RHD PF00554.17 KFP06624.1 - 3.4e-24 85.4 0.6 4.3e-22 78.6 0.1 3.1 3 1 0 3 3 3 2 Rel homology domain (RHD) TIG PF01833.19 KFP06624.1 - 2.5e-05 24.1 0.1 0.00016 21.5 0.1 2.6 1 1 0 1 1 1 1 IPT/TIG domain AA_permease PF00324.16 KFP06625.1 - 4.1e-62 210.0 33.3 2.7e-37 128.2 5.0 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KFP06625.1 - 4.4e-16 58.4 38.8 2.5e-15 55.9 9.1 2.1 2 0 0 2 2 2 2 Amino acid permease KCl_Cotrans_1 PF03522.10 KFP06625.1 - 1.6e-11 43.5 0.1 3.7e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 K-Cl Co-transporter type 1 (KCC1) SNF PF00209.13 KFP06626.1 - 4.7e-238 790.8 34.0 5.4e-238 790.6 23.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EF-hand_1 PF00036.27 KFP06627.1 - 1.4e-19 67.8 9.0 1.3e-05 24.1 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KFP06627.1 - 4e-17 60.5 4.5 9e-05 22.0 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFP06627.1 - 1.1e-15 56.9 9.7 3.3e-06 26.5 0.0 4.2 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.1 KFP06627.1 - 5.2e-15 55.3 9.5 8.5e-10 38.6 0.8 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP06627.1 - 8.3e-15 53.3 11.1 0.00013 21.1 0.1 4.0 4 0 0 4 4 4 3 EF hand Acyltransferase PF01553.16 KFP06627.1 - 4.9e-13 48.6 0.0 8.5e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase EF-hand_4 PF12763.2 KFP06627.1 - 0.00067 19.3 1.4 0.53 10.0 0.0 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KFP06627.1 - 0.0044 17.0 0.0 0.035 14.1 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KFP06627.1 - 0.24 11.0 1.6 0.95 9.1 0.1 2.7 3 0 0 3 3 3 0 EF hand Peptidase_M10 PF00413.19 KFP06628.1 - 1.2e-65 219.8 0.2 1.2e-64 216.7 0.1 2.2 1 1 0 1 1 1 1 Matrixin fn2 PF00040.14 KFP06628.1 - 5.6e-56 186.2 36.7 5.2e-19 67.9 2.4 3.7 3 0 0 3 3 3 3 Fibronectin type II domain Hemopexin PF00045.14 KFP06628.1 - 6.7e-42 140.9 9.4 5.9e-13 48.3 0.4 4.6 4 0 0 4 4 4 4 Hemopexin PG_binding_1 PF01471.13 KFP06628.1 - 3.8e-09 36.3 0.0 9.1e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Reprolysin_3 PF13582.1 KFP06628.1 - 0.0069 16.8 0.1 0.051 14.0 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 KFP06628.1 - 0.012 14.9 0.0 4.7 6.5 0.0 2.5 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 KFP06628.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF3152 PF11350.3 KFP06628.1 - 0.12 11.9 0.0 0.82 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) Reprolysin_2 PF13574.1 KFP06628.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Homeobox_KN PF05920.6 KFP06629.1 - 1.7e-16 59.6 0.2 2.8e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFP06629.1 - 5.6e-09 35.4 1.9 6.8e-09 35.2 1.3 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP06629.1 - 0.0052 15.8 0.1 0.0092 15.0 0.0 1.5 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez MRP-S32 PF10210.4 KFP06629.1 - 0.13 12.6 2.0 0.14 12.5 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Phage_P2_GpE PF06528.7 KFP06629.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Phage P2 GpE Homeobox_KN PF05920.6 KFP06633.1 - 5.1e-16 58.0 0.3 8.5e-16 57.3 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFP06633.1 - 7.5e-09 35.0 0.4 9.1e-09 34.8 0.3 1.1 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP06633.1 - 0.0045 16.0 0.1 0.0092 15.0 0.0 1.6 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 KFP06633.1 - 0.016 15.2 0.1 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 Helicase associated domain MRP-S32 PF10210.4 KFP06633.1 - 0.05 13.9 1.1 0.06 13.6 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 FTO_CTD PF12934.2 KFP06634.1 - 1.2e-13 50.9 0.2 1.3e-13 50.9 0.2 1.0 1 0 0 1 1 1 1 FTO C-terminal domain Ribosomal_L31 PF01197.13 KFP06634.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L31 FTO_NTD PF12933.2 KFP06635.1 - 1.7e-100 335.3 0.0 2.5e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.2 KFP06635.1 - 2.4e-46 157.4 3.7 4.4e-46 156.6 2.6 1.4 1 0 0 1 1 1 1 FTO C-terminal domain DUF3250 PF11618.3 KFP06636.1 - 2e-42 143.7 9.4 1.5e-36 124.8 0.4 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3250) C2 PF00168.25 KFP06636.1 - 1e-07 31.6 0.1 2.9e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 C2 domain ATG16 PF08614.6 KFP06636.1 - 0.0025 17.6 6.5 0.0025 17.6 4.5 5.9 3 2 2 5 5 5 1 Autophagy protein 16 (ATG16) UQ_con PF00179.21 KFP06637.1 - 5.8e-22 77.6 0.0 8.8e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RB_A PF01858.12 KFP06638.1 - 8.4e-78 260.5 0.4 2.1e-77 259.2 0.3 1.7 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.15 KFP06638.1 - 3.6e-57 191.6 0.0 1.8e-56 189.3 0.0 2.3 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.3 KFP06638.1 - 1.2e-44 150.9 0.1 3.8e-44 149.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) BCS1_N PF08740.6 KFP06638.1 - 0.032 13.8 0.8 0.28 10.7 0.2 2.2 2 0 0 2 2 2 0 BCS1 N terminal Imm-NTF2 PF15655.1 KFP06638.1 - 0.072 13.5 0.3 0.21 12.0 0.2 1.8 1 0 0 1 1 1 0 NTF2 fold immunity protein HMG_box PF00505.14 KFP06640.1 - 6.9e-18 64.6 0.4 1.8e-17 63.3 0.2 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP06640.1 - 1.3e-12 47.9 0.7 5.8e-12 45.7 0.5 2.2 1 0 0 1 1 1 1 HMG-box domain PA-IL PF07828.7 KFP06640.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 PA-IL-like protein zf-C2H2 PF00096.21 KFP06641.1 - 1.6e-33 112.9 74.5 4.6e-05 23.5 0.1 10.6 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP06641.1 - 4.5e-32 108.0 65.2 0.00011 22.2 0.4 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP06641.1 - 1.4e-29 100.8 73.9 4e-08 33.1 0.7 12.0 13 0 0 13 13 12 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP06641.1 - 1.1e-27 95.4 42.5 0.00011 22.1 1.2 9.5 9 0 0 9 9 9 8 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP06641.1 - 3.8e-26 90.4 53.0 0.00057 20.0 0.4 9.8 9 0 0 9 9 9 8 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP06641.1 - 6e-08 32.3 56.2 0.047 13.6 1.1 9.6 9 0 0 9 9 9 5 C2H2-type zinc finger IZUMO PF15005.1 KFP06641.1 - 0.00012 22.1 0.3 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 Izumo sperm-egg fusion zf-C2HC_2 PF13913.1 KFP06641.1 - 0.01 15.5 39.0 1.1 8.9 0.1 8.0 8 0 0 8 8 8 3 zinc-finger of a C2HC-type BolA PF01722.13 KFP06641.1 - 0.013 15.3 6.1 4.5 7.3 0.0 5.0 5 0 0 5 5 5 0 BolA-like protein zf-C2H2_2 PF12756.2 KFP06641.1 - 0.046 13.8 46.7 1.2 9.2 0.7 9.1 5 4 5 10 10 10 0 C2H2 type zinc-finger (2 copies) Imm-NTF2-2 PF15631.1 KFP06641.1 - 0.15 12.0 0.0 1.4e+02 2.5 0.0 3.9 4 0 0 4 4 4 0 NTF2 fold immunity protein Elf1 PF05129.8 KFP06641.1 - 2 8.1 29.3 0.87 9.3 0.7 5.7 4 1 1 5 5 5 0 Transcription elongation factor Elf1 like Rad50_zn_hook PF04423.9 KFP06641.1 - 6.8 6.2 10.4 7.5 6.1 0.0 5.0 5 0 0 5 5 5 0 Rad50 zinc hook motif PX PF00787.19 KFP06642.1 - 6.6e-16 58.1 6.4 1.7e-15 56.8 2.6 2.6 3 0 0 3 3 3 1 PX domain TPR_12 PF13424.1 KFP06642.1 - 0.0018 18.1 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Ocnus PF05005.10 KFP06642.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) TPR_11 PF13414.1 KFP06642.1 - 0.076 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 TPR repeat EF-hand_6 PF13405.1 KFP06643.1 - 0.0017 18.0 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain Nitroreductase PF00881.19 KFP06643.1 - 0.0044 16.8 0.2 0.071 12.9 0.0 2.3 2 1 0 2 2 2 1 Nitroreductase family EF-hand_1 PF00036.27 KFP06643.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 EF hand Ribosomal_L23 PF00276.15 KFP06643.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L23 EF-hand_7 PF13499.1 KFP06643.1 - 0.024 14.7 0.0 0.088 12.9 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair DUF3512 PF12024.3 KFP06644.1 - 2.1e-88 295.7 0.1 2.1e-88 295.7 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.20 KFP06644.1 - 4.7e-22 77.6 1.6 9.8e-22 76.6 1.1 1.6 1 0 0 1 1 1 1 Bromodomain DUF2796 PF10986.3 KFP06644.1 - 4 7.3 11.1 0.06 13.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) PAP_assoc PF03828.14 KFP06645.1 - 1.5e-15 56.9 0.1 4.8e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFP06645.1 - 7.2e-15 55.0 0.1 1.8e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain HEAT_2 PF13646.1 KFP06646.1 - 6e-07 29.6 5.5 0.00062 19.9 0.0 4.3 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KFP06646.1 - 3.3e-06 26.7 9.1 0.12 12.4 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KFP06646.1 - 4.8e-06 26.8 1.3 0.00045 20.6 0.3 4.2 3 2 1 4 4 4 1 HEAT-like repeat Arm PF00514.18 KFP06646.1 - 0.003 17.3 0.1 0.003 17.3 0.0 5.9 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat Tmemb_18A PF09771.4 KFP06647.1 - 3.6e-59 198.2 0.4 3.9e-59 198.1 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 188 CopD PF05425.8 KFP06647.1 - 0.0036 17.4 0.1 0.0044 17.2 0.0 1.1 1 0 0 1 1 1 1 Copper resistance protein D DUF418 PF04235.7 KFP06647.1 - 0.047 13.3 0.3 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF418) zf-C2H2 PF00096.21 KFP06648.1 - 1.6e-58 191.6 220.0 0.00022 21.3 0.8 30.8 31 0 0 31 31 31 27 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP06648.1 - 2.4e-49 162.1 203.8 0.005 17.0 0.4 30.5 31 0 0 31 31 31 22 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP06648.1 - 1.8e-41 138.3 193.7 5e-05 23.3 0.3 31.4 33 0 0 33 33 33 20 Zinc-finger double domain zf-Di19 PF05605.7 KFP06648.1 - 1.3e-24 86.0 188.4 9.1e-05 22.5 1.3 20.3 17 4 3 22 22 22 14 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFP06648.1 - 4.5e-21 74.0 165.7 2.2e-06 27.3 0.1 27.1 29 1 1 30 30 30 13 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP06648.1 - 2.3e-19 68.9 162.8 0.0011 19.0 0.8 26.3 26 2 2 28 28 28 14 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP06648.1 - 1.1e-05 25.5 174.1 0.38 10.8 4.2 24.8 7 5 9 19 19 19 7 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFP06648.1 - 0.00097 19.2 8.0 0.0028 17.7 1.5 23.5 26 0 0 26 26 26 8 Zinc-finger of C2H2 type C1q PF00386.16 KFP06649.1 - 1e-20 74.0 0.1 1.1e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 C1q domain RNase_Zc3h12a PF11977.3 KFP06650.1 - 2.6e-57 193.0 0.0 5.8e-57 191.8 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Sina PF03145.11 KFP06651.1 - 4e-81 271.4 0.2 6.3e-81 270.7 0.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family Lon_C PF05362.8 KFP06652.1 - 1.7e-79 265.8 0.0 2.8e-79 265.2 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KFP06652.1 - 8.3e-22 77.8 0.0 2.9e-21 76.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KFP06652.1 - 1.8e-16 60.4 0.3 1.8e-16 60.4 0.2 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KFP06652.1 - 6.5e-09 35.6 0.0 1.7e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFP06652.1 - 2.8e-06 27.4 0.3 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ChlI PF13541.1 KFP06652.1 - 7.7e-06 25.4 0.0 2.3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.6 KFP06652.1 - 0.00017 21.2 0.0 0.00041 19.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFP06652.1 - 0.00075 20.3 0.0 0.0031 18.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KFP06652.1 - 0.0015 17.3 0.0 0.015 13.9 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.9 KFP06652.1 - 0.0018 18.2 0.0 0.0051 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KFP06652.1 - 0.0034 16.1 0.2 0.8 8.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus DUF258 PF03193.11 KFP06652.1 - 0.0036 16.4 0.0 0.0087 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFP06652.1 - 0.0037 17.3 0.0 0.035 14.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFP06652.1 - 0.0057 16.9 0.3 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFP06652.1 - 0.012 14.6 0.0 0.04 12.9 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 KFP06652.1 - 0.013 15.4 0.0 0.042 13.7 0.0 1.9 1 0 0 1 1 1 0 Shikimate kinase AAA_33 PF13671.1 KFP06652.1 - 0.038 13.8 0.5 0.1 12.5 0.0 2.0 3 0 0 3 3 1 0 AAA domain IstB_IS21 PF01695.12 KFP06652.1 - 0.039 13.3 0.2 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 KFP06652.1 - 0.04 13.6 0.0 0.15 11.7 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KFP06652.1 - 0.05 13.5 0.0 0.62 9.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 KFP06652.1 - 0.068 12.7 3.2 0.14 11.7 0.3 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KFP06652.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Birna_VP4 PF01768.11 KFP06652.1 - 0.14 11.2 0.1 0.28 10.1 0.0 1.5 1 0 0 1 1 1 0 Birnavirus VP4 protein Glyco_hydro_15 PF00723.16 KFP06653.1 - 5.3e-108 361.4 0.0 6.9e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 VCBS PF13517.1 KFP06654.1 - 8.6e-15 54.8 17.3 3.6e-05 24.0 1.2 5.1 2 2 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFP06654.1 - 1.5e-11 43.6 7.9 0.098 12.3 0.1 6.1 6 0 0 6 6 6 4 FG-GAP repeat K1 PF02960.9 KFP06654.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 K1 glycoprotein CUB PF00431.15 KFP06655.1 - 3.8e-42 142.8 0.2 2.1e-27 95.3 0.0 2.9 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.13 KFP06655.1 - 3.1e-06 26.9 4.7 3.1e-06 26.9 3.2 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A CTDII PF01556.13 KFP06656.1 - 2.3e-25 88.3 0.1 6.4e-23 80.4 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KFP06656.1 - 4.4e-17 61.5 0.9 8.2e-17 60.6 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KFP06656.1 - 3.5e-07 30.1 11.1 7.2e-07 29.1 7.7 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFP06656.1 - 0.38 10.4 2.3 2 8.1 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Borealin PF10512.4 KFP06657.1 - 3e-12 46.4 0.0 3.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 RHD PF00554.17 KFP06657.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 1 0 1 1 1 0 Rel homology domain (RHD) Aminotran_1_2 PF00155.16 KFP06658.1 - 1.2e-32 113.3 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II UPF0547 PF10571.4 KFP06659.1 - 0.00091 18.8 2.4 0.0015 18.2 1.7 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 G-7-MTase PF12803.2 KFP06659.1 - 0.2 10.7 2.2 0.68 9.0 1.0 1.8 1 1 1 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Vfa1 PF08432.5 KFP06659.1 - 0.25 11.3 7.6 0.29 11.1 5.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 KFP06659.1 - 1.5 8.6 6.2 1.6 8.5 4.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dsh_C PF12316.3 KFP06659.1 - 6.1 6.8 7.3 7.5 6.6 5.1 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal NPR3 PF03666.8 KFP06659.1 - 7.5 4.9 8.4 8.7 4.7 5.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase PF00069.20 KFP06660.1 - 7.9e-20 71.0 0.0 9e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06660.1 - 1.2e-05 24.5 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Vps35 PF03635.12 KFP06661.1 - 0 1013.2 14.2 0 1013.0 9.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 FerA PF08165.6 KFP06661.1 - 0.015 14.9 0.1 0.066 12.8 0.0 2.2 1 0 0 1 1 1 0 FerA (NUC095) domain 7tm_1 PF00001.16 KFP06662.1 - 1.5e-62 211.1 9.1 2.1e-62 210.5 6.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06662.1 - 4.3e-08 32.6 15.5 8.2e-06 25.1 5.7 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP06662.1 - 4.1e-05 22.8 11.6 4.1e-05 22.8 8.1 2.0 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF4491 PF14898.1 KFP06662.1 - 0.022 14.8 1.0 0.1 12.7 0.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4491) YesK PF14150.1 KFP06662.1 - 0.64 10.1 11.5 0.75 9.9 1.0 3.4 2 1 1 3 3 3 0 YesK-like protein Beta_helix PF13229.1 KFP06663.1 - 3.6e-11 43.0 0.2 6.6e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 KFP06663.1 - 2.5e-08 33.4 0.0 4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.2 KFP06663.1 - 0.022 14.8 0.1 1.3 9.0 0.0 2.4 1 1 1 2 2 2 0 Pectate lyase superfamily protein Hormone_recep PF00104.25 KFP06664.1 - 2.2e-39 134.6 0.0 2.8e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-DHHC PF01529.15 KFP06665.1 - 4.1e-39 133.7 9.2 4.1e-39 133.7 6.3 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase PorB PF11565.3 KFP06666.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha helical Porin B Fork_head PF00250.13 KFP06668.1 - 2.8e-44 149.0 0.0 3e-44 148.9 0.0 1.0 1 0 0 1 1 1 1 Fork head domain Fork_head PF00250.13 KFP06669.1 - 3.6e-46 155.1 0.1 5.9e-46 154.4 0.1 1.3 1 0 0 1 1 1 1 Fork head domain 5-FTHF_cyc-lig PF01812.15 KFP06670.1 - 1.3e-23 83.7 0.0 2.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.17 KFP06670.1 - 5.7e-05 22.6 0.0 0.00016 21.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP06670.1 - 9.4e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06670.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fork_head PF00250.13 KFP06671.1 - 2e-39 133.4 0.0 7.7e-39 131.6 0.0 1.9 2 0 0 2 2 2 1 Fork head domain I-set PF07679.11 KFP06672.1 - 5.8e-77 253.6 0.0 1.6e-13 50.3 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP06672.1 - 9.5e-63 208.3 3.0 1.7e-10 40.8 0.0 7.5 7 0 0 7 7 7 6 Immunoglobulin domain Ig_3 PF13927.1 KFP06672.1 - 1.2e-42 144.2 15.2 1.4e-07 31.8 0.0 8.1 8 1 0 8 8 7 6 Immunoglobulin domain ig PF00047.20 KFP06672.1 - 7.2e-38 128.5 0.1 3.1e-07 30.4 0.0 7.5 6 1 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 KFP06672.1 - 5.3e-33 112.9 16.0 1.1e-10 41.4 0.3 4.7 4 0 0 4 4 4 4 Fibronectin type III domain V-set PF07686.12 KFP06672.1 - 7e-33 112.9 3.5 5.8e-07 29.4 0.0 8.7 8 2 0 8 8 8 5 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP06672.1 - 3.1e-08 33.3 1.7 0.3 10.9 0.0 5.8 6 0 0 6 6 6 2 CD80-like C2-set immunoglobulin domain Sp38 PF07354.7 KFP06672.1 - 1.3e-05 24.0 0.1 0.11 11.0 0.0 4.1 4 0 0 4 4 4 1 Zona-pellucida-binding protein (Sp38) Tissue_fac PF01108.12 KFP06672.1 - 1.9e-05 24.3 2.6 0.017 14.8 0.1 3.2 2 1 1 3 3 3 2 Tissue factor C2-set PF05790.10 KFP06672.1 - 0.0063 16.4 0.1 32 4.5 0.0 5.5 5 1 1 6 6 6 0 Immunoglobulin C2-set domain Interfer-bind PF09294.5 KFP06672.1 - 0.0078 16.2 0.2 7.2 6.7 0.0 3.0 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III I-set PF07679.11 KFP06673.1 - 4e-69 228.5 0.0 6.6e-14 51.5 0.0 6.7 6 0 0 6 6 6 6 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP06673.1 - 1.6e-53 178.7 0.1 4.5e-09 36.3 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin domain fn3 PF00041.16 KFP06673.1 - 1.8e-42 143.3 14.4 1.5e-15 57.0 0.1 4.5 4 0 0 4 4 4 4 Fibronectin type III domain Ig_3 PF13927.1 KFP06673.1 - 5.4e-41 138.9 9.4 3.7e-08 33.7 0.0 8.1 9 0 0 9 9 9 6 Immunoglobulin domain ig PF00047.20 KFP06673.1 - 3e-40 136.1 0.0 4.7e-08 33.0 0.0 7.1 6 0 0 6 6 6 6 Immunoglobulin domain V-set PF07686.12 KFP06673.1 - 9.7e-36 122.1 1.0 4.3e-08 33.0 0.0 7.9 4 3 2 6 6 6 6 Immunoglobulin V-set domain V-set_CD47 PF08204.6 KFP06673.1 - 2.2e-05 24.2 0.8 9.8 5.9 0.0 4.8 4 0 0 4 4 4 2 CD47 immunoglobulin-like domain Tissue_fac PF01108.12 KFP06673.1 - 2.5e-05 23.9 2.6 0.018 14.8 0.1 3.4 2 1 1 3 3 3 2 Tissue factor C2-set_2 PF08205.7 KFP06673.1 - 0.00014 21.7 0.2 0.5 10.2 0.0 4.2 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Sp38 PF07354.7 KFP06673.1 - 0.00082 18.1 0.0 0.33 9.5 0.0 3.8 5 0 0 5 5 5 1 Zona-pellucida-binding protein (Sp38) Herpes_gE PF02480.11 KFP06673.1 - 0.022 13.0 0.9 7.1 4.7 0.0 4.2 5 1 0 6 6 6 0 Alphaherpesvirus glycoprotein E IL6Ra-bind PF09240.5 KFP06674.1 - 1.3e-24 86.2 0.3 6.1e-24 84.0 0.1 2.1 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFP06674.1 - 9e-06 25.3 9.5 0.0044 16.7 0.4 3.5 2 2 1 3 3 3 2 Tissue factor fn3 PF00041.16 KFP06674.1 - 0.0053 16.8 1.5 0.55 10.4 0.1 3.1 3 0 0 3 3 3 1 Fibronectin type III domain EpoR_lig-bind PF09067.5 KFP06674.1 - 0.022 14.7 1.2 0.067 13.1 0.8 1.8 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding PolyA_pol PF01743.15 KFP06675.1 - 1e-31 109.7 0.3 1.7e-31 109.0 0.2 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KFP06675.1 - 9.5e-13 47.5 0.0 6.1e-12 44.9 0.0 2.1 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KFP06675.1 - 0.041 13.7 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative UPF0181 PF03701.9 KFP06675.1 - 0.12 11.6 0.4 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) LON PF02190.11 KFP06676.1 - 5.1e-21 75.2 0.0 6.9e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Yippee-Mis18 PF03226.9 KFP06676.1 - 0.069 13.2 5.7 0.07 13.1 2.6 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LRR_8 PF13855.1 KFP06677.1 - 9.6e-50 166.1 66.4 2.2e-12 46.5 4.1 6.8 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFP06677.1 - 3.9e-31 106.1 45.1 3.9e-09 35.9 1.0 7.9 4 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP06677.1 - 3.3e-24 85.0 1.0 2.5e-11 43.4 2.4 3.8 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) I-set PF07679.11 KFP06677.1 - 2e-16 59.5 0.1 1.1e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain LRR_1 PF00560.28 KFP06677.1 - 5.9e-12 43.8 38.2 0.011 15.6 0.1 12.4 13 0 0 13 13 13 3 Leucine Rich Repeat LRR_7 PF13504.1 KFP06677.1 - 2.1e-11 42.0 19.9 1.7 9.2 0.0 11.3 12 0 0 12 12 11 4 Leucine rich repeat LRR_6 PF13516.1 KFP06677.1 - 8e-09 34.6 36.1 0.071 13.2 0.3 11.2 10 1 1 11 11 11 4 Leucine Rich repeat Ig_3 PF13927.1 KFP06677.1 - 2.1e-08 34.5 0.7 5.5e-08 33.1 0.1 2.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.12 KFP06677.1 - 3.1e-08 33.4 0.0 8.9e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin V-set domain LRR_9 PF14580.1 KFP06677.1 - 1.7e-07 31.0 18.8 0.016 14.7 1.5 4.3 1 1 3 4 4 4 3 Leucine-rich repeat Ig_2 PF13895.1 KFP06677.1 - 3.5e-07 30.2 0.0 1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP06677.1 - 2.9e-05 24.1 1.7 0.00017 21.6 0.1 3.1 3 1 0 3 3 3 1 Immunoglobulin domain LRRNT PF01462.13 KFP06677.1 - 0.00014 21.2 1.0 0.00014 21.2 0.7 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain fn3 PF00041.16 KFP06677.1 - 0.0015 18.5 1.1 0.0037 17.3 0.8 1.7 1 0 0 1 1 1 1 Fibronectin type III domain LRRCT PF01463.19 KFP06677.1 - 0.0059 16.7 0.1 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain SET PF00856.23 KFP06678.1 - 3.5e-26 92.4 0.0 1.3e-25 90.6 0.0 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 KFP06678.1 - 2e-07 31.2 9.4 2e-07 31.2 6.5 1.8 2 0 0 2 2 2 1 Pre-SET motif TCR PF03638.10 KFP06678.1 - 1.7 8.5 21.0 0.44 10.4 2.0 3.2 3 0 0 3 3 3 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain FGE-sulfatase PF03781.11 KFP06679.1 - 3.3e-87 292.1 5.8 3.7e-87 291.9 4.0 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 RYDR_ITPR PF01365.16 KFP06680.1 - 2e-128 425.6 26.5 5.4e-72 241.3 0.4 4.0 5 0 0 5 5 5 2 RIH domain Ins145_P3_rec PF08709.6 KFP06680.1 - 1.6e-98 327.9 0.0 3.8e-96 320.2 0.0 2.6 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.14 KFP06680.1 - 7.3e-72 240.8 0.0 6.9e-70 234.4 0.0 2.5 2 0 0 2 2 2 1 MIR domain RIH_assoc PF08454.6 KFP06680.1 - 1.4e-32 111.5 6.4 1.4e-32 111.5 4.5 5.1 5 1 0 5 5 5 1 RyR and IP3R Homology associated Ion_trans PF00520.26 KFP06680.1 - 6.5e-09 35.3 9.2 6.5e-09 35.3 6.4 2.4 2 0 0 2 2 2 1 Ion transport protein Hairy_orange PF07527.8 KFP06681.1 - 3.1e-09 36.4 0.4 7.9e-09 35.1 0.2 1.8 1 0 0 1 1 1 1 Hairy Orange Arf PF00025.16 KFP06682.1 - 1e-39 135.5 0.1 1.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP06682.1 - 4.1e-15 55.5 0.0 4.6e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06682.1 - 9.4e-07 29.3 0.0 3e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KFP06682.1 - 2.9e-06 26.6 0.0 3.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFP06682.1 - 1.4e-05 23.9 0.1 2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFP06682.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP06682.1 - 0.0041 16.3 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Glyco_hydro_47 PF01532.15 KFP06683.1 - 9.7e-139 462.8 0.0 1.1e-138 462.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ANF_receptor PF01094.23 KFP06685.1 - 5.6e-100 334.5 0.0 7e-100 334.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFP06685.1 - 2.8e-85 285.4 14.0 4e-85 284.9 9.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFP06685.1 - 8.3e-15 54.2 9.8 1.6e-14 53.3 6.8 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFP06685.1 - 1.5e-10 40.9 0.0 1.4e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 Periplasmic binding protein DUF2318 PF10080.4 KFP06685.1 - 0.063 13.0 1.5 0.18 11.5 1.0 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Caveolin PF01146.12 KFP06686.1 - 4.7e-66 220.9 1.6 5e-66 220.8 1.1 1.0 1 0 0 1 1 1 1 Caveolin 7tm_1 PF00001.16 KFP06687.1 - 3.7e-42 144.2 14.6 4.2e-42 144.0 10.1 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06687.1 - 0.0017 17.5 12.3 0.0025 16.9 8.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Vma12 PF11712.3 KFP06687.1 - 1.3 8.6 3.1 1.3 8.6 0.4 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4118 PF13493.1 KFP06687.1 - 7.4 6.8 10.7 0.89 9.7 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) MENTAL PF10457.4 KFP06687.1 - 8.3 5.9 10.9 7.9 6.0 4.5 2.6 2 1 0 2 2 2 0 Cholesterol-capturing domain SAP PF02037.22 KFP06688.1 - 8.6e-09 34.7 0.2 1.8e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_6 PF14835.1 KFP06688.1 - 8e-08 31.9 9.4 3.3e-07 29.9 3.3 2.5 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 KFP06688.1 - 3.8e-07 29.6 10.2 3.8e-07 29.6 7.1 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP06688.1 - 2.7e-06 27.2 11.0 2.7e-06 27.2 7.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP06688.1 - 3.3e-05 23.6 12.3 3.3e-05 23.6 8.5 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFP06688.1 - 0.0014 18.2 16.3 0.0014 18.2 6.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP06688.1 - 0.002 17.7 13.0 0.002 17.7 9.0 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFP06688.1 - 0.014 15.5 6.7 0.014 15.5 4.7 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger SPT16 PF08644.6 KFP06688.1 - 0.3 10.9 5.1 0.72 9.6 3.6 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) zf-RING_UBOX PF13445.1 KFP06688.1 - 1.8 8.3 12.8 0.026 14.2 3.4 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFP06688.1 - 5.8 6.8 20.7 0.94 9.4 10.4 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RhoGAP PF00620.22 KFP06689.1 - 1.1e-47 161.4 0.0 4e-47 159.6 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KFP06689.1 - 6.8e-20 71.0 4.9 2.8e-19 69.0 3.4 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFP06689.1 - 9.1e-11 41.1 0.0 1.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP06689.1 - 2.4e-10 39.6 0.0 9.8e-10 37.6 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFP06689.1 - 2.4e-10 39.7 0.0 6e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.6 KFP06689.1 - 0.008 16.0 0.4 0.052 13.4 0.2 2.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Flg_hook PF02120.11 KFP06689.1 - 0.026 14.1 0.8 0.079 12.6 0.5 1.8 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK UPF0020 PF01170.13 KFP06690.1 - 4.6e-44 150.1 0.0 6.9e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KFP06690.1 - 1.5e-15 57.2 0.0 2.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain THUMP PF02926.12 KFP06690.1 - 1.7e-13 50.6 0.3 7.2e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 THUMP domain Methyltransf_31 PF13847.1 KFP06690.1 - 0.00011 21.8 0.0 0.00045 19.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP06690.1 - 0.015 15.7 0.0 0.067 13.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KFP06690.1 - 0.023 14.0 0.0 0.071 12.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KFP06690.1 - 0.06 13.9 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2457 PF10446.4 KFP06690.1 - 8.5 4.9 17.7 11 4.5 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VHL PF01847.11 KFP06691.1 - 7.2e-68 227.0 0.2 8.1e-68 226.8 0.2 1.0 1 0 0 1 1 1 1 von Hippel-Lindau disease tumour suppressor protein STAT2_C PF12188.3 KFP06691.1 - 0.08 12.7 1.3 0.2 11.5 0.1 2.2 3 0 0 3 3 3 0 Signal transducer and activator of transcription 2 C terminal WD40 PF00400.27 KFP06692.1 - 1.1e-47 158.3 21.5 3.3e-10 39.4 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFP06692.1 - 0.11 12.1 12.5 0.32 10.7 0.2 4.3 2 2 2 4 4 4 0 Transcription factor IIIC subunit delta N-term Ribosomal_L32e PF01655.13 KFP06693.1 - 1.6e-50 169.7 4.1 2e-50 169.4 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 CAAP1 PF15335.1 KFP06693.1 - 0.11 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 DUF1947 PF09183.5 KFP06693.1 - 0.18 11.5 1.9 0.3 10.8 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) HhH-GPD PF00730.20 KFP06694.1 - 3.8e-07 30.3 0.0 4.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein WD40 PF00400.27 KFP06695.1 - 2.1e-26 90.7 14.3 9.3e-10 38.0 0.0 7.3 6 1 0 6 6 6 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFP06695.1 - 1.4e-06 27.4 5.8 0.0019 17.0 0.2 5.0 5 1 0 5 5 5 2 Coatomer WD associated region zf-RING_2 PF13639.1 KFP06695.1 - 0.003 17.3 3.5 0.014 15.1 2.4 2.3 1 0 0 1 1 1 1 Ring finger domain Apc3 PF12895.2 KFP06695.1 - 0.0043 17.1 7.8 1.6 8.8 0.2 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 KFP06695.1 - 0.0055 16.2 1.5 0.34 10.5 0.0 3.3 1 1 2 3 3 3 1 Region in Clathrin and VPS eIF2A PF08662.6 KFP06695.1 - 0.0078 15.9 0.5 0.56 9.8 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_7 PF13176.1 KFP06695.1 - 0.029 14.1 9.4 0.032 14.0 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFP06695.1 - 0.14 12.1 19.6 0.32 11.0 0.5 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFP06695.1 - 0.65 9.6 8.8 28 4.4 1.5 4.9 5 1 0 5 5 5 0 TPR repeat TPR_12 PF13424.1 KFP06695.1 - 1 9.3 8.1 1.2 9.1 0.1 4.1 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFP06695.1 - 4.7 8.1 7.2 47 5.0 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat 7tm_1 PF00001.16 KFP06696.1 - 7.9e-50 169.3 14.8 1.1e-49 168.9 10.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rhodopsin_N PF10413.4 KFP06696.1 - 7.6e-26 89.4 1.5 2.1e-25 88.0 1.0 1.9 1 0 0 1 1 1 1 Amino terminal of the G-protein receptor rhodopsin 7TM_GPCR_Srw PF10324.4 KFP06696.1 - 8.8e-09 34.9 18.4 3e-08 33.1 12.7 1.8 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.4 KFP06696.1 - 2.5e-08 33.3 19.9 3.6e-08 32.8 13.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFP06696.1 - 3.6e-08 32.8 17.3 5.5e-08 32.2 12.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP06696.1 - 0.00019 20.6 21.1 0.00026 20.1 14.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srh PF10318.4 KFP06696.1 - 0.00042 19.2 10.9 0.00042 19.2 7.5 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh TAS2R PF05296.8 KFP06696.1 - 0.0011 17.9 11.5 0.0029 16.5 1.4 2.1 2 0 0 2 2 2 2 Mammalian taste receptor protein (TAS2R) 60KD_IMP PF02096.15 KFP06696.1 - 0.24 11.0 8.0 0.41 10.2 4.7 2.0 1 1 1 2 2 2 0 60Kd inner membrane protein DUF788 PF05620.6 KFP06696.1 - 0.48 10.2 0.0 0.48 10.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF788) Tmemb_cc2 PF10267.4 KFP06698.1 - 2.9e-180 599.0 14.6 2.9e-180 599.0 10.1 1.6 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein TRH PF05438.7 KFP06699.1 - 4.3e-52 176.5 13.7 6.4e-50 169.4 4.8 2.0 1 1 1 2 2 2 2 Thyrotropin-releasing hormone (TRH) Chal_sti_synt_C PF02797.10 KFP06699.1 - 2.7e-05 24.1 0.0 6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Med2 PF11214.3 KFP06699.1 - 0.032 14.2 0.0 0.078 13.0 0.0 1.8 1 0 0 1 1 1 0 Mediator complex subunit 2 Rbsn PF11464.3 KFP06700.1 - 1.5e-43 146.1 15.7 9.8e-22 76.2 0.4 2.7 2 0 0 2 2 2 2 Rabenosyn Rab binding domain FYVE PF01363.16 KFP06700.1 - 6.1e-19 67.6 6.3 2.1e-18 65.9 4.3 2.0 1 0 0 1 1 1 1 FYVE zinc finger HypA PF01155.14 KFP06700.1 - 0.0035 17.0 0.4 0.0035 17.0 0.3 3.2 4 0 0 4 4 4 1 Hydrogenase expression/synthesis hypA family TerY-C PF15616.1 KFP06700.1 - 0.026 14.4 1.8 0.22 11.4 0.1 2.9 2 0 0 2 2 2 0 TerY-C metal binding domain RNA_POL_M_15KD PF02150.11 KFP06700.1 - 0.16 11.7 4.9 0.28 10.9 0.5 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-RING_3 PF14369.1 KFP06700.1 - 0.55 10.2 6.8 0.21 11.5 0.2 3.0 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 KFP06700.1 - 3.2 7.6 13.4 2.2 8.1 3.4 3.2 3 1 0 3 3 3 0 Double zinc ribbon L51_S25_CI-B8 PF05047.11 KFP06701.1 - 1.1e-13 50.6 0.9 2.4e-13 49.5 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RICH PF05062.7 KFP06701.1 - 0.13 12.4 2.8 0.22 11.6 1.9 1.3 1 0 0 1 1 1 0 RICH domain Hormone_recep PF00104.25 KFP06702.1 - 1.6e-35 122.1 2.0 2.7e-35 121.3 1.4 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP06702.1 - 4.2e-32 110.1 16.3 8.5e-32 109.2 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) XS PF03468.9 KFP06702.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 XS domain Reo_sigmaC PF04582.7 KFP06704.1 - 0.18 10.9 19.8 0.063 12.4 2.4 4.2 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Raptor_N PF14538.1 KFP06704.1 - 0.42 10.4 0.0 0.42 10.4 0.0 3.9 3 2 1 5 5 5 0 Raptor N-terminal CASPase like domain zf-C2H2 PF00096.21 KFP06705.1 - 1.9e-15 56.1 20.5 7.1e-06 26.0 1.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP06705.1 - 3e-12 46.1 6.9 2.3e-07 30.7 0.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP06705.1 - 8e-11 41.4 19.8 0.00063 19.8 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFP06705.1 - 0.0016 18.5 6.2 0.039 14.1 0.5 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFP06705.1 - 0.057 13.6 15.5 0.17 12.1 0.0 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain IBR PF01485.16 KFP06705.1 - 0.22 11.4 4.4 1.1 9.1 3.0 2.0 1 1 0 1 1 1 0 IBR domain zf-C2H2_6 PF13912.1 KFP06705.1 - 0.6 10.0 3.8 0.46 10.4 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 KFP06705.1 - 2 8.2 10.1 4.6 7.0 1.0 2.6 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 KFP06705.1 - 8.2 6.7 11.2 3.6 7.8 0.1 3.4 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFP06706.1 - 2e-14 52.9 22.9 8.5e-06 25.8 2.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP06706.1 - 1.8e-11 43.7 8.9 8.5e-08 32.1 1.0 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP06706.1 - 1.5e-07 31.2 20.5 0.0081 16.4 0.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFP06706.1 - 0.016 15.3 3.6 2.3 8.5 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP06706.1 - 0.11 12.7 4.0 4.2 7.6 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP06706.1 - 2 8.4 7.5 0.42 10.5 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HCaRG PF07258.9 KFP06707.1 - 2.4e-25 89.0 0.0 2.9e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 HCaRG protein Peptidase_C12 PF01088.16 KFP06708.1 - 8.4e-73 244.0 0.0 9.4e-73 243.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 LMP PF04778.7 KFP06708.1 - 0.059 13.1 0.5 0.085 12.6 0.4 1.2 1 0 0 1 1 1 0 LMP repeated region CH PF00307.26 KFP06709.1 - 2e-08 34.2 0.0 9.4e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain PDZ PF00595.19 KFP06709.1 - 5.3e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 KFP06709.1 - 7.9e-07 29.0 8.1 2e-06 27.7 5.6 1.8 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 KFP06709.1 - 0.00018 21.3 0.0 0.00046 20.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DNA_pol_B_palm PF14792.1 KFP06710.1 - 5.2e-40 135.9 0.0 1.1e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KFP06710.1 - 4.5e-22 77.3 0.1 2.5e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KFP06710.1 - 9e-18 63.7 0.0 1.7e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KFP06710.1 - 7.2e-12 45.3 0.7 3.8e-10 39.8 0.3 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KFP06710.1 - 8.9e-10 38.5 0.2 1.1e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.18 KFP06710.1 - 0.00086 18.8 0.2 0.93 9.3 0.2 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.2 KFP06710.1 - 0.002 17.9 0.0 0.62 9.9 0.0 2.7 1 1 1 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.3 KFP06710.1 - 0.0088 15.9 0.0 0.041 13.8 0.0 2.1 1 1 0 1 1 1 1 Pathogenicity locus NTP_transf_2 PF01909.18 KFP06710.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_3 PF12836.2 KFP06710.1 - 0.03 14.2 0.6 5 7.1 0.0 3.3 4 1 0 4 4 4 0 Helix-hairpin-helix motif DUF3701 PF12482.3 KFP06710.1 - 0.09 12.5 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Phage integrase protein Porin_3 PF01459.17 KFP06711.1 - 3.7e-79 265.8 6.5 4.1e-79 265.6 4.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin PagL PF09411.5 KFP06711.1 - 0.08 13.0 1.3 2.6 8.1 0.3 2.7 1 1 2 3 3 3 0 Lipid A 3-O-deacylase (PagL) Pkinase PF00069.20 KFP06712.1 - 1.4e-41 142.4 0.0 4.9e-41 140.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06712.1 - 5.3e-27 94.5 0.0 1.4e-26 93.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.3 KFP06712.1 - 8.1e-19 67.1 8.4 8.1e-19 67.1 5.8 2.7 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain ubiquitin PF00240.18 KFP06712.1 - 2.3e-05 23.6 0.2 7.1e-05 22.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Kdo PF06293.9 KFP06712.1 - 8.7e-05 21.6 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP06712.1 - 0.00097 18.9 0.6 0.0048 16.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP06712.1 - 0.0025 17.1 0.0 0.0065 15.8 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL NPV_P10 PF05531.7 KFP06712.1 - 0.66 10.2 5.0 8.4 6.7 0.6 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-C4H2 PF10146.4 KFP06712.1 - 8.3 6.3 8.1 3.5 7.5 1.3 2.8 1 1 0 2 2 2 0 Zinc finger-containing protein Trypsin PF00089.21 KFP06713.1 - 3.8e-68 229.3 0.0 5.6e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFP06713.1 - 1.5e-46 156.3 28.1 2.3e-24 85.2 3.7 3.1 4 0 0 4 4 4 2 Kringle domain fn1 PF00039.13 KFP06713.1 - 0.00066 19.4 4.1 0.0051 16.5 2.8 2.7 1 0 0 1 1 1 1 Fibronectin type I domain DUF316 PF03761.10 KFP06713.1 - 0.0064 15.8 0.1 3.1 7.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF316) Adap_comp_sub PF00928.16 KFP06714.1 - 2.6e-74 249.6 0.0 3.2e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFP06714.1 - 3.4e-05 23.5 0.8 6.2e-05 22.7 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyltransferase PF01553.16 KFP06716.1 - 1.9e-18 66.1 0.1 3.7e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase FTCD_N PF07837.7 KFP06716.1 - 0.12 11.8 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Formiminotransferase domain, N-terminal subdomain Sld5 PF05916.6 KFP06717.1 - 7.1e-06 26.2 0.1 9.7e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein Erf4 PF10256.4 KFP06718.1 - 1.4e-21 76.5 0.0 1.5e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3920 PF13058.1 KFP06718.1 - 0.071 12.9 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) TC1 PF15063.1 KFP06719.1 - 5.2e-39 131.6 0.2 6.4e-39 131.3 0.1 1.1 1 0 0 1 1 1 1 Thyroid cancer protein 1 Toprim_4 PF13662.1 KFP06719.1 - 0.042 13.8 0.3 0.043 13.8 0.2 1.3 1 1 0 1 1 1 0 Toprim domain R3H-assoc PF13902.1 KFP06719.1 - 0.071 13.0 0.2 0.11 12.4 0.1 1.3 1 1 0 1 1 1 0 R3H-associated N-terminal domain Reprolysin PF01421.14 KFP06720.1 - 6.6e-66 221.7 0.0 1.2e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFP06720.1 - 1.3e-39 135.0 0.4 2.8e-39 133.8 0.3 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR PF08516.7 KFP06720.1 - 1.4e-38 131.5 6.8 1.4e-38 131.5 4.7 3.3 3 0 0 3 3 1 1 ADAM cysteine-rich Disintegrin PF00200.18 KFP06720.1 - 6.8e-23 80.6 28.4 6.8e-23 80.6 19.7 4.5 3 1 1 4 4 3 1 Disintegrin Reprolysin_5 PF13688.1 KFP06720.1 - 1.8e-21 76.9 0.2 5.2e-21 75.4 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFP06720.1 - 2.1e-19 70.2 0.1 4.6e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP06720.1 - 1.3e-13 51.3 0.7 2.6e-13 50.4 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP06720.1 - 6.7e-13 48.6 0.1 1.1e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EGF_2 PF07974.8 KFP06720.1 - 0.0022 18.1 11.8 0.0022 18.1 8.1 6.9 7 1 1 8 8 5 1 EGF-like domain Peptidase_M10 PF00413.19 KFP06720.1 - 0.011 15.5 0.1 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 KFP06720.1 - 0.02 13.7 0.5 0.035 12.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.3 KFP06720.1 - 0.039 13.2 1.2 0.069 12.4 0.8 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M43 PF05572.8 KFP06720.1 - 0.052 13.1 0.1 0.052 13.1 0.1 2.0 2 0 0 2 2 1 0 Pregnancy-associated plasma protein-A NDUF_B5 PF09781.4 KFP06720.1 - 0.17 11.1 0.2 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit PH PF00169.24 KFP06721.1 - 2.8e-19 69.2 0.6 4.6e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFP06721.1 - 1.3e-12 47.9 0.6 0.00011 22.4 0.0 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFP06721.1 - 9.8e-08 31.9 2.6 0.00026 21.0 0.1 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 KFP06721.1 - 0.00028 20.8 0.0 0.00054 19.8 0.0 1.5 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 KFP06721.1 - 0.0011 19.0 0.0 0.0059 16.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Pkinase_Tyr PF07714.12 KFP06722.1 - 4.2e-104 347.2 0.0 6.2e-104 346.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06722.1 - 4.6e-49 166.9 0.0 6.9e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFP06722.1 - 1.3e-37 127.4 0.0 5.2e-14 51.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP06722.1 - 1.6e-28 98.6 0.1 1.5e-09 37.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP06722.1 - 5.8e-22 77.5 0.6 1.5e-06 28.2 0.0 4.4 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP06722.1 - 3.8e-17 62.5 0.1 7.7e-06 26.3 0.0 4.5 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP06722.1 - 1.9e-12 47.0 1.6 0.00052 19.8 0.0 4.9 3 3 0 3 3 3 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP06722.1 - 0.00014 21.6 0.2 0.21 11.5 0.0 3.8 2 1 2 4 4 4 1 CD80-like C2-set immunoglobulin domain Herpes_gE PF02480.11 KFP06722.1 - 0.042 12.1 4.3 6.9 4.8 0.0 3.2 3 1 0 3 3 3 0 Alphaherpesvirus glycoprotein E V-set_CD47 PF08204.6 KFP06722.1 - 0.063 13.0 0.1 0.81 9.4 0.0 2.7 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain DUF4396 PF14342.1 KFP06722.1 - 0.13 12.3 0.5 0.22 11.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) LETM1 PF07766.8 KFP06723.1 - 3.3e-106 354.2 7.4 3.8e-106 354.0 5.1 1.0 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KFP06723.1 - 0.024 14.1 0.1 0.12 11.9 0.1 2.2 1 1 0 1 1 1 0 SAP domain SET PF00856.23 KFP06724.1 - 4.8e-25 88.7 0.5 4.8e-25 88.7 0.3 2.7 2 1 0 2 2 2 1 SET domain PWWP PF00855.12 KFP06724.1 - 3.3e-16 59.2 1.2 3.3e-16 59.2 0.8 2.4 2 1 0 2 2 2 1 PWWP domain PHD PF00628.24 KFP06724.1 - 8.2e-15 54.2 72.9 2.4e-06 27.1 4.6 6.6 4 2 2 6 6 6 4 PHD-finger zf-HC5HC2H PF13771.1 KFP06724.1 - 0.011 15.8 14.3 0.011 15.8 9.9 6.4 2 2 3 5 5 5 0 PHD-like zinc-binding domain PAP2 PF01569.16 KFP06725.1 - 5.7e-26 90.7 3.6 2.2e-25 88.8 1.1 2.0 2 0 0 2 2 2 1 PAP2 superfamily YhhN PF07947.9 KFP06725.1 - 0.034 13.5 6.8 0.072 12.4 2.3 2.6 1 1 1 2 2 2 0 YhhN-like protein PAP2_C PF14360.1 KFP06725.1 - 0.074 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 PAP2 superfamily C-terminal DDHD PF02862.12 KFP06726.1 - 1.7e-52 178.4 0.0 2.6e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 DDHD domain SAM_1 PF00536.25 KFP06726.1 - 3.3e-14 52.8 0.0 5.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WWE PF02825.15 KFP06726.1 - 4.5e-13 48.4 1.2 2e-07 30.3 0.0 2.8 1 1 1 2 2 2 2 WWE domain SAM_2 PF07647.12 KFP06726.1 - 2.1e-06 27.5 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KFP06726.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 IGR protein motif LSM PF01423.17 KFP06727.1 - 0.0013 18.1 0.1 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 KFP06728.1 - 2.9e-49 167.5 0.0 4e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06728.1 - 1.4e-27 96.4 0.0 2e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06728.1 - 3.5e-05 22.8 0.0 5.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RGS PF00615.14 KFP06728.1 - 0.014 15.5 0.1 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Regulator of G protein signaling domain APH PF01636.18 KFP06728.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family START PF01852.14 KFP06729.1 - 1.3e-43 148.6 0.0 1.6e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc PF03364.15 KFP06729.1 - 0.0076 16.2 0.0 0.025 14.5 0.0 1.9 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport TB2_DP1_HVA22 PF03134.14 KFP06730.1 - 1e-20 73.2 10.0 1.4e-20 72.8 6.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Halogen_Hydrol PF10112.4 KFP06730.1 - 0.18 11.1 0.6 0.2 11.0 0.4 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PH PF00169.24 KFP06731.1 - 9.5e-07 28.9 0.0 1e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 PH domain Polysacc_synt_4 PF04669.8 KFP06732.1 - 0.0097 15.2 0.0 0.0098 15.2 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis IBN_N PF03810.14 KFP06733.1 - 2.8e-11 43.1 1.6 1.3e-10 41.0 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_C PF08767.6 KFP06733.1 - 0.00054 18.9 0.4 0.0018 17.2 0.3 1.9 1 0 0 1 1 1 1 CRM1 C terminal GDNF PF02351.11 KFP06734.1 - 2.4e-45 152.9 43.7 2.8e-20 72.6 3.8 3.1 3 0 0 3 3 3 3 GDNF/GAS1 domain ATP-synt_ab PF00006.20 KFP06735.1 - 7.2e-62 208.6 0.0 9.7e-62 208.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFP06735.1 - 1.9e-17 63.7 0.1 3.9e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFP06735.1 - 6.6e-12 45.4 0.4 1.6e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KFP06735.1 - 0.013 15.4 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain Glyco_hydro_31 PF01055.21 KFP06736.1 - 1.7e-151 505.0 5.4 2.4e-151 504.5 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Trefoil PF00088.13 KFP06736.1 - 4.3e-19 67.8 13.9 1.7e-11 43.5 4.2 2.6 2 0 0 2 2 2 2 Trefoil (P-type) domain dUTPase PF00692.14 KFP06738.1 - 1.1e-17 63.7 0.0 1.4e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP06738.1 - 0.00063 19.6 0.0 0.0029 17.4 0.0 2.0 2 1 1 3 3 3 1 Retroviral aspartyl protease RVT_1 PF00078.22 KFP06739.1 - 2.6e-25 89.0 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFP06739.1 - 0.048 13.2 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase thumb domain rve PF00665.21 KFP06740.1 - 2.9e-28 98.3 0.1 5.5e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 KFP06740.1 - 2.9e-13 49.0 0.4 5.2e-13 48.1 0.2 1.5 1 0 0 1 1 1 1 Integrase Zinc binding domain RNase_H PF00075.19 KFP06740.1 - 3.6e-09 37.0 0.0 6.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 RNase H DDE_Tnp_IS240 PF13610.1 KFP06740.1 - 7.2e-06 26.0 0.1 8.2e-05 22.5 0.0 2.2 2 1 1 3 3 3 1 DDE domain Baculo_LEF5_C PF11792.3 KFP06740.1 - 0.023 14.0 0.1 0.045 13.1 0.1 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain rve_3 PF13683.1 KFP06740.1 - 0.027 14.0 0.0 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain KH_1 PF00013.24 KFP06741.1 - 2.5e-43 145.5 12.6 3.4e-19 68.2 0.9 3.5 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFP06741.1 - 4.4e-34 115.5 11.0 6.9e-13 47.9 2.5 3.7 3 0 0 3 3 3 3 KH domain ROKNT PF08067.6 KFP06741.1 - 5.9e-23 80.4 9.8 9.6e-23 79.7 6.8 1.3 1 0 0 1 1 1 1 ROKNT (NUC014) domain KH_2 PF07650.12 KFP06741.1 - 1e-15 57.0 2.3 0.00055 19.4 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFP06741.1 - 2.1e-07 30.4 8.6 7.8e-06 25.4 0.2 3.4 3 1 0 3 3 3 2 KH domain KH_5 PF13184.1 KFP06741.1 - 7.1e-05 22.5 2.1 0.7 9.7 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain Phi-29_GP3 PF05435.6 KFP06741.1 - 0.029 13.6 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 C1q PF00386.16 KFP06742.1 - 3.9e-17 62.4 0.3 8.4e-17 61.3 0.2 1.6 1 0 0 1 1 1 1 C1q domain EMI PF07546.8 KFP06742.1 - 2.1e-15 56.9 3.3 3.9e-15 56.0 2.3 1.5 1 0 0 1 1 1 1 EMI domain Phlebovirus_NSM PF07246.6 KFP06742.1 - 0.0074 15.4 0.7 0.0074 15.4 0.5 3.0 3 1 1 4 4 4 1 Phlebovirus nonstructural protein NS-M Synuclein PF01387.12 KFP06743.1 - 1.4e-52 177.0 25.6 1.6e-52 176.8 17.7 1.0 1 0 0 1 1 1 1 Synuclein Apolipoprotein PF01442.13 KFP06743.1 - 0.018 14.5 0.2 0.02 14.4 0.2 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MoaF PF10703.4 KFP06743.1 - 0.047 12.7 1.3 0.048 12.7 0.9 1.0 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F DSRB PF10781.4 KFP06743.1 - 0.088 12.3 0.4 0.51 9.8 0.1 2.3 1 1 1 2 2 2 0 Dextransucrase DSRB EndoU_bacteria PF14436.1 KFP06743.1 - 0.1 12.4 1.8 0.12 12.1 1.3 1.1 1 0 0 1 1 1 0 Bacterial EndoU nuclease YtxH PF12732.2 KFP06743.1 - 3.1 8.2 6.7 19 5.7 4.6 2.0 1 1 0 1 1 1 0 YtxH-like protein Augurin PF15187.1 KFP06744.1 - 5.7e-19 68.0 2.7 6.1e-19 67.9 1.9 1.0 1 0 0 1 1 1 1 Oesophageal cancer-related gene 4 ELFV_dehydrog PF00208.16 KFP06745.1 - 1.7e-55 188.2 0.0 9.5e-53 179.2 0.0 2.1 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFP06745.1 - 2.8e-34 117.5 0.0 5.1e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AlaDh_PNT_C PF01262.16 KFP06745.1 - 0.026 14.1 0.1 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFP06745.1 - 0.043 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SF3b10 PF07189.6 KFP06745.1 - 0.11 12.3 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) GRIN_C PF15235.1 KFP06747.1 - 2.6e-44 150.6 0.3 7.4e-44 149.1 0.2 1.8 1 0 0 1 1 1 1 G protein-regulated inducer of neurite outgrowth C-terminus ARA70 PF12489.3 KFP06748.1 - 1.9e-68 228.4 37.1 5.2e-38 130.0 3.5 5.4 5 2 0 5 5 5 3 Nuclear coactivator Tim17 PF02466.14 KFP06749.1 - 1.7e-18 66.8 2.3 1.9e-18 66.7 1.6 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family APG6 PF04111.7 KFP06749.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PARG_cat PF05028.9 KFP06750.1 - 6.5e-130 433.3 0.0 9.7e-130 432.7 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) E1_dh PF00676.15 KFP06751.1 - 3.5e-83 278.7 0.1 6e-83 278.0 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 KFP06751.1 - 2.4e-67 225.8 0.0 3.7e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Carn_acyltransf PF00755.15 KFP06752.1 - 1.5e-216 720.0 0.0 1.7e-216 719.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.11 KFP06753.1 - 2.4e-28 98.8 33.9 4.4e-27 94.7 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 KFP06753.1 - 0.0065 15.2 0.3 0.0065 15.2 0.2 1.5 2 0 0 2 2 2 1 BT1 family LacY_symp PF01306.14 KFP06753.1 - 0.16 10.5 4.8 0.13 10.8 0.7 2.2 2 1 0 2 2 2 0 LacY proton/sugar symporter 7tm_1 PF00001.16 KFP06754.1 - 1.5e-24 86.5 13.1 4.2e-23 81.7 9.0 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06754.1 - 0.045 12.9 6.5 0.087 11.9 4.5 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx E1_dh PF00676.15 KFP06754.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component 7TM_GPCR_Srx PF10328.4 KFP06754.1 - 0.38 9.8 14.5 0.029 13.4 3.0 2.6 2 1 1 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srx LRR_8 PF13855.1 KFP06755.1 - 3.8e-30 103.4 13.1 3e-13 49.3 2.3 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP06755.1 - 1.5e-13 49.9 22.5 3.9e-06 26.3 1.6 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP06755.1 - 3e-11 41.7 3.4 0.042 13.8 0.0 4.8 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_7 PF13504.1 KFP06755.1 - 4.6e-07 28.9 12.0 0.069 13.3 0.2 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFP06755.1 - 0.0025 17.7 5.2 0.21 11.7 0.1 3.7 3 1 0 3 3 3 2 Leucine Rich repeat I-set PF07679.11 KFP06755.1 - 0.0032 17.2 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Cadherin PF00028.12 KFP06756.1 - 1.1e-69 230.7 5.4 8.3e-16 58.0 0.0 6.4 6 0 0 6 6 6 6 Cadherin domain He_PIG PF05345.7 KFP06756.1 - 0.015 15.3 3.2 2.9 8.0 0.0 4.7 5 0 0 5 5 5 0 Putative Ig domain DUF1720 PF08226.6 KFP06757.1 - 3.5 7.7 8.0 0.86 9.7 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) IQ PF00612.22 KFP06758.1 - 2e-06 26.9 1.5 2e-06 26.9 1.0 2.8 3 0 0 3 3 3 1 IQ calmodulin-binding motif OmpH PF03938.9 KFP06758.1 - 0.09 12.7 2.7 2.4 8.0 1.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GAS PF13851.1 KFP06758.1 - 5 6.2 14.5 0.23 10.6 3.1 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Oxysterol_BP PF01237.13 KFP06759.1 - 1.3e-11 43.5 0.2 2.3e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KFP06759.1 - 2.6e-05 24.1 0.0 9.5e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Syntaxin-6_N PF09177.6 KFP06759.1 - 0.0012 19.2 5.0 0.085 13.2 0.4 3.3 2 1 1 3 3 3 1 Syntaxin 6, N-terminal PH PF00169.24 KFP06759.1 - 0.0017 18.5 0.0 0.0048 17.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 KFP06759.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Herpes_IE68 PF02479.11 KFP06759.1 - 0.031 13.4 1.2 0.1 11.7 0.2 2.2 2 0 0 2 2 2 0 Herpesvirus immediate early protein DUF1284 PF06935.6 KFP06759.1 - 0.034 14.3 0.8 0.076 13.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) MbeD_MobD PF04899.7 KFP06759.1 - 0.1 12.4 2.1 0.44 10.4 0.3 2.3 2 0 0 2 2 2 0 MbeD/MobD like DUF4061 PF13270.1 KFP06759.1 - 0.44 10.6 3.0 14 5.8 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) MerR-DNA-bind PF09278.6 KFP06759.1 - 0.85 10.0 9.0 0.7 10.3 2.9 2.6 2 1 0 2 2 2 0 MerR, DNA binding DUF4254 PF14063.1 KFP06759.1 - 1.9 8.1 6.8 5.3 6.6 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4254) CENP-F_leu_zip PF10473.4 KFP06759.1 - 8.2 6.2 11.2 0.74 9.6 2.1 2.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Oxysterol_BP PF01237.13 KFP06760.1 - 2.2e-24 85.6 0.1 2.5e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Pro_dh PF01619.13 KFP06762.1 - 2.1e-81 273.3 0.3 2.6e-81 273.0 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase His_Phos_1 PF00300.17 KFP06762.1 - 0.045 13.8 0.3 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) HrpB2 PF09487.5 KFP06762.1 - 0.1 12.8 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Laminin_EGF PF00053.19 KFP06763.1 - 6.2e-23 80.4 175.7 0.003 17.4 9.4 11.0 2 1 8 10 10 10 9 Laminin EGF-like (Domains III and V) hEGF PF12661.2 KFP06763.1 - 0.028 14.5 1.6 0.028 14.5 1.1 17.4 21 0 0 21 21 21 0 Human growth factor-like EGF DGCR6 PF07324.6 KFP06764.1 - 5e-52 176.2 6.7 5.4e-52 176.1 4.7 1.0 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein MEKHLA PF08670.6 KFP06764.1 - 0.024 14.1 0.1 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 MEKHLA domain DUF2458 PF10454.4 KFP06764.1 - 0.04 13.7 2.4 0.049 13.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) AA_permease_2 PF13520.1 KFP06765.1 - 2.5e-49 167.9 39.4 2.5e-49 167.9 27.3 1.9 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFP06765.1 - 1.7e-38 132.1 44.3 1.8e-38 132.1 23.2 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.1 KFP06765.1 - 8.9e-21 73.5 8.6 8.9e-21 73.5 6.0 4.2 3 1 0 3 3 3 1 C-terminus of AA_permease P2X_receptor PF00864.14 KFP06766.1 - 1.3e-123 412.4 0.2 1.4e-123 412.3 0.2 1.0 1 0 0 1 1 1 1 ATP P2X receptor WAP PF00095.16 KFP06766.1 - 0.12 12.3 3.3 0.14 12.1 0.9 2.1 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Transmemb_17 PF09799.4 KFP06767.1 - 1.8e-19 70.0 4.7 2e-19 69.9 3.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein DUF221 PF02714.10 KFP06767.1 - 0.089 11.6 3.2 0.092 11.5 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF221 TPT PF03151.11 KFP06767.1 - 0.24 11.0 1.8 0.27 10.8 1.3 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family Pyr_redox_2 PF07992.9 KFP06768.1 - 9.3e-35 120.3 0.0 8.1e-34 117.2 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFP06768.1 - 3.1e-19 69.1 1.3 1.2e-14 54.4 0.2 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KFP06768.1 - 5.5e-16 57.9 0.1 1.3e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.19 KFP06768.1 - 1.7e-10 40.3 0.8 0.00029 19.8 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFP06768.1 - 3.1e-10 40.4 0.9 3.7e-05 23.8 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFP06768.1 - 1e-08 34.1 3.4 0.003 16.0 0.1 4.0 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.1 KFP06768.1 - 1e-07 31.8 0.1 0.00033 20.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Reductase_C PF14759.1 KFP06768.1 - 1.3e-07 31.7 0.0 3.8e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.1 KFP06768.1 - 2e-07 30.7 0.0 1.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain FAD_binding_3 PF01494.14 KFP06768.1 - 4.6e-06 25.9 0.2 0.0014 17.8 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 KFP06768.1 - 1.1e-05 24.5 4.0 0.0014 17.5 0.0 3.8 3 1 1 4 4 4 1 FAD binding domain Lycopene_cycl PF05834.7 KFP06768.1 - 1.8e-05 23.8 1.1 0.16 10.8 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 KFP06768.1 - 3.9e-05 22.7 1.1 0.64 8.8 0.0 3.9 3 1 1 4 4 4 2 Glucose inhibited division protein A Thi4 PF01946.12 KFP06768.1 - 0.0002 20.5 1.0 0.18 10.8 0.0 3.0 3 0 0 3 3 3 2 Thi4 family NAD_binding_9 PF13454.1 KFP06768.1 - 0.00039 20.2 0.5 1.6 8.4 0.0 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFP06768.1 - 0.0019 17.1 0.1 0.027 13.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Malic_M PF03949.10 KFP06768.1 - 0.0044 16.6 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 1 1 Malic enzyme, NAD binding domain Shikimate_DH PF01488.15 KFP06768.1 - 0.0049 16.9 0.1 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KFP06768.1 - 0.0053 16.7 0.1 4.1 7.4 0.0 2.9 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.13 KFP06768.1 - 0.012 15.3 0.0 0.73 9.4 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KFP06768.1 - 0.013 15.2 4.2 0.27 11.0 0.0 3.0 3 0 0 3 3 3 0 ThiF family ApbA PF02558.11 KFP06768.1 - 0.034 13.5 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KFP06768.1 - 0.04 13.6 0.0 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 KFP06768.1 - 0.05 13.8 1.3 1.6 9.0 0.0 3.0 2 1 0 3 3 3 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFP06768.1 - 0.07 12.2 0.1 2.3 7.3 0.0 2.8 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFP06768.1 - 0.099 12.0 0.8 3.3 7.0 0.1 2.8 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 KFP06768.1 - 0.12 10.9 1.3 4.6 5.7 0.0 2.7 2 1 1 3 3 3 0 Tryptophan halogenase DUF1744 PF08490.7 KFP06769.1 - 3e-151 503.4 0.1 4.9e-151 502.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KFP06769.1 - 1e-80 271.0 0.9 1.2e-79 267.5 0.2 2.3 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KFP06769.1 - 2.3e-22 79.4 0.4 8e-21 74.3 0.1 3.0 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KFP06769.1 - 1.5e-08 34.4 0.3 5.3e-08 32.6 0.2 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KFP06769.1 - 1.1e-06 28.5 1.2 1.2e-05 25.1 0.0 3.2 3 1 0 4 4 4 1 RNase_H superfamily NAD_binding_9 PF13454.1 KFP06769.1 - 0.27 10.9 0.8 0.74 9.5 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding APP_N PF02177.11 KFP06769.1 - 0.52 10.2 6.8 0.048 13.5 0.2 2.4 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding DUF4544 PF15077.1 KFP06770.1 - 3.8e-11 42.9 0.2 5.9e-11 42.3 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4544) Phospholip_A2_2 PF05826.7 KFP06771.1 - 1.7e-20 72.8 0.4 2.3e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 Phospholipase A2 Exo_endo_phos PF03372.18 KFP06772.1 - 7e-27 94.9 0.1 9.4e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CALCOCO1 PF07888.6 KFP06772.1 - 1.2e-08 33.7 0.3 1.6e-08 33.3 0.2 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Smoothelin PF12510.3 KFP06773.1 - 3.2e-38 129.3 39.5 9.7e-18 63.7 7.7 3.7 3 0 0 3 3 3 3 Smoothelin cytoskeleton protein CH PF00307.26 KFP06773.1 - 2.4e-21 75.7 0.1 5.2e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP06773.1 - 1.4e-09 37.4 0.0 2.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain HATPase_c_3 PF13589.1 KFP06774.1 - 1.7e-18 66.5 0.3 5.6e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.10 KFP06774.1 - 3.1e-17 62.0 4.5 7.9e-17 60.6 3.1 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger Atg14 PF10186.4 KFP06774.1 - 7.9 5.3 18.3 1.8 7.4 1.8 3.4 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Phe_tRNA-synt_N PF02912.13 KFP06776.1 - 0.056 13.1 0.3 4.8 6.9 0.0 3.0 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain FERM_C PF09380.5 KFP06777.1 - 1.5e-35 121.2 0.4 3.3e-35 120.1 0.0 1.8 2 0 0 2 2 2 1 FERM C-terminal PH-like domain ERM PF00769.14 KFP06777.1 - 5.4e-25 88.3 46.0 5.4e-25 88.3 31.9 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family FERM_M PF00373.13 KFP06777.1 - 1.4e-24 86.6 1.0 1.4e-24 86.6 0.7 2.9 2 1 1 3 3 3 1 FERM central domain FERM_N PF09379.5 KFP06777.1 - 9.2e-13 48.0 0.2 9.2e-13 48.0 0.1 2.7 3 1 0 3 3 3 1 FERM N-terminal domain DUF956 PF06115.6 KFP06777.1 - 0.092 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF956) EF-hand_1 PF00036.27 KFP06778.1 - 0.00093 18.3 0.3 0.031 13.5 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KFP06778.1 - 0.0014 17.9 0.7 0.067 12.5 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFP06778.1 - 0.004 16.7 0.6 0.41 10.3 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP06778.1 - 0.067 13.0 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KFP06778.1 - 0.1 12.7 1.3 4.8 7.3 0.1 2.3 2 1 0 2 2 2 0 EF-hand domain pair zf-CCCH PF00642.19 KFP06779.1 - 7.4e-09 35.0 2.3 1.2e-08 34.3 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-U1 PF06220.7 KFP06779.1 - 5.7e-08 32.1 3.9 1.2e-07 31.1 2.7 1.6 1 0 0 1 1 1 1 U1 zinc finger IFRD PF05004.8 KFP06779.1 - 0.039 13.0 0.0 0.79 8.7 0.0 2.0 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) zf-C2H2_jaz PF12171.3 KFP06779.1 - 0.51 10.5 10.9 0.8 9.9 5.8 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCCH_2 PF14608.1 KFP06779.1 - 0.63 10.1 4.6 2.9 8.0 3.2 2.0 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type UCR_UQCRX_QCR9 PF05365.7 KFP06780.1 - 2.4e-27 94.3 0.1 2.5e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Myotub-related PF06602.9 KFP06781.1 - 4.6e-147 489.4 0.2 6.8e-147 488.8 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KFP06781.1 - 0.00016 21.0 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP06781.1 - 0.0021 17.6 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP06781.1 - 0.0025 18.0 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family HORMA PF02301.13 KFP06782.1 - 1.5e-45 155.2 0.0 2e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 HORMA domain LIF_OSM PF01291.12 KFP06783.1 - 2.5e-29 102.3 0.6 2.7e-29 102.1 0.4 1.0 1 0 0 1 1 1 1 LIF / OSM family PqqD PF05402.7 KFP06783.1 - 0.06 13.3 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) CcmH PF03918.9 KFP06783.1 - 0.085 11.8 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein ACT_7 PF13840.1 KFP06784.1 - 1.3e-26 91.8 0.2 1.2e-18 66.4 0.1 2.3 2 0 0 2 2 2 2 ACT domain RabGAP-TBC PF00566.13 KFP06785.1 - 1.7e-54 184.5 0.0 2.4e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRRCT PF01463.19 KFP06785.1 - 0.14 12.5 2.1 30 5.3 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain CENP-F_leu_zip PF10473.4 KFP06786.1 - 0.042 13.7 82.1 0.089 12.6 16.1 4.9 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 KFP06786.1 - 0.11 12.3 0.2 0.11 12.3 0.1 5.7 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) GAS PF13851.1 KFP06786.1 - 0.32 10.1 70.6 0.53 9.4 0.2 4.2 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF2400 PF09674.5 KFP06786.1 - 8.2 6.0 9.4 1.7 8.3 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) zf-RING_2 PF13639.1 KFP06787.1 - 8.3e-14 51.1 9.2 2e-13 49.8 6.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFP06787.1 - 2.8e-07 30.0 6.1 6.9e-07 28.8 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP06787.1 - 3.6e-07 30.1 9.5 1.3e-06 28.4 6.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFP06787.1 - 1.9e-06 27.4 6.1 3.7e-06 26.5 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP06787.1 - 5.1e-06 26.0 3.6 9.7e-06 25.1 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP06787.1 - 2e-05 24.5 7.2 5e-05 23.2 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFP06787.1 - 0.07 12.9 5.2 0.2 11.5 3.6 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HTH_31 PF13560.1 KFP06787.1 - 0.31 11.2 0.2 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain CRAL_TRIO PF00650.15 KFP06788.1 - 2.2e-41 140.9 0.0 3e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KFP06788.1 - 4.7e-07 29.8 0.0 7.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain GOLD_2 PF13897.1 KFP06788.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Gal-3-0_sulfotr PF06990.6 KFP06789.1 - 4.2e-154 513.0 2.2 4.7e-154 512.9 1.5 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.1 KFP06789.1 - 0.16 12.8 2.9 0.2 12.5 1.6 1.5 1 1 0 1 1 1 0 Sulfotransferase family Pescadillo_N PF06732.6 KFP06790.1 - 2.2e-119 397.8 1.6 2.2e-119 397.8 1.1 2.4 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KFP06790.1 - 6.7e-09 35.7 0.0 3.2e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Nucleoplasmin PF03066.10 KFP06790.1 - 0.0014 18.1 10.6 0.0014 18.1 7.3 2.1 3 0 0 3 3 3 1 Nucleoplasmin CDC45 PF02724.9 KFP06790.1 - 0.073 11.1 13.8 0.14 10.1 9.6 1.4 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 KFP06790.1 - 0.95 8.4 11.2 12 4.7 7.7 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Cobalamin_bind PF01122.14 KFP06791.1 - 1.3e-72 244.1 0.0 1.4e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF533 PF04391.7 KFP06791.1 - 0.031 13.6 0.1 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Peptidase_C69 PF03577.10 KFP06792.1 - 1.2e-08 34.2 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.11 KFP06792.1 - 0.12 11.8 0.0 0.76 9.1 0.0 2.2 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase zf-H2C2_2 PF13465.1 KFP06793.1 - 2.8e-12 46.2 5.1 7.5e-07 29.1 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP06793.1 - 3.5e-11 42.7 30.9 3.5e-05 23.8 0.7 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP06793.1 - 1.7e-08 34.1 20.0 0.0015 18.6 0.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP06793.1 - 0.0066 16.5 5.8 24 5.2 0.0 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP06793.1 - 0.056 13.3 18.8 0.24 11.3 1.9 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.10 KFP06793.1 - 1.5 8.6 11.9 0.028 14.1 2.1 2.5 1 1 2 3 3 3 0 BED zinc finger zf-C2H2 PF00096.21 KFP06794.1 - 1.8e-14 53.1 7.8 2.3e-08 33.8 0.6 2.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP06794.1 - 1.5e-11 43.9 6.9 5.7e-10 38.9 0.5 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP06794.1 - 2.3e-10 40.0 6.5 0.00015 21.8 0.3 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KFP06794.1 - 6.3e-09 35.7 4.1 7.2e-05 22.8 0.3 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP06794.1 - 1.4e-08 34.3 3.2 0.00016 21.4 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP06794.1 - 1.8e-08 34.2 1.2 0.0013 18.8 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFP06794.1 - 9.9e-05 22.3 0.8 0.00015 21.8 0.6 1.3 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 KFP06794.1 - 0.00052 19.4 0.9 0.043 13.2 0.1 2.1 2 0 0 2 2 2 1 Rad50 zinc hook motif Zn-ribbon_8 PF09723.5 KFP06794.1 - 0.00077 19.3 1.4 0.013 15.4 1.0 2.0 1 1 0 1 1 1 1 Zinc ribbon domain ADK_lid PF05191.9 KFP06794.1 - 0.0015 18.1 2.0 0.012 15.2 0.1 2.4 2 1 0 2 2 2 1 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.1 KFP06794.1 - 0.0021 17.4 0.0 0.003 16.9 0.0 1.3 1 1 0 1 1 1 1 zinc-ribbon domain zf-LYAR PF08790.6 KFP06794.1 - 0.003 17.2 2.3 0.5 10.1 0.1 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Prok-RING_1 PF14446.1 KFP06794.1 - 0.0031 17.2 0.9 0.52 10.0 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-TFIIB PF13453.1 KFP06794.1 - 0.0043 16.2 0.4 0.011 14.9 0.3 1.6 1 1 0 1 1 1 1 Transcription factor zinc-finger BolA PF01722.13 KFP06794.1 - 0.0049 16.8 0.2 1.7 8.6 0.0 2.0 1 1 1 2 2 2 1 BolA-like protein zf-H2C2_5 PF13909.1 KFP06794.1 - 0.0052 16.9 4.3 0.5 10.7 0.1 2.5 2 1 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 KFP06794.1 - 0.0058 16.7 0.8 0.45 10.6 0.2 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) Prok-RING_4 PF14447.1 KFP06794.1 - 0.013 15.0 1.1 0.17 11.4 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 KFP06794.1 - 0.013 15.2 1.1 0.02 14.6 0.8 1.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 KFP06794.1 - 0.014 15.0 0.9 0.028 14.0 0.6 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CGNR PF11706.3 KFP06794.1 - 0.022 14.2 3.0 0.75 9.3 0.2 2.1 2 0 0 2 2 2 0 CGNR zinc finger zinc_ribbon_5 PF13719.1 KFP06794.1 - 0.024 14.2 1.7 1.5 8.4 1.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFP06794.1 - 0.029 13.5 2.0 0.54 9.5 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFP06794.1 - 0.029 14.0 1.6 1.8 8.3 1.1 2.1 1 1 0 1 1 1 0 zinc-ribbon domain DUF329 PF03884.9 KFP06794.1 - 0.029 13.9 1.6 2 8.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF329) DUF2225 PF09986.4 KFP06794.1 - 0.031 13.7 1.3 0.47 9.8 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) XPA_N PF01286.13 KFP06794.1 - 0.034 13.8 0.7 1.7 8.3 0.1 2.1 2 0 0 2 2 2 0 XPA protein N-terminal HNH PF01844.18 KFP06794.1 - 0.035 13.9 1.5 3.2 7.6 0.1 2.2 2 0 0 2 2 2 0 HNH endonuclease UPF0547 PF10571.4 KFP06794.1 - 0.037 13.7 4.3 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-HYPF PF07503.7 KFP06794.1 - 0.04 13.3 2.2 1.4 8.3 2.1 2.2 1 1 1 2 2 2 0 HypF finger zf-BED PF02892.10 KFP06794.1 - 0.044 13.5 1.6 5.5 6.8 0.1 2.1 1 1 0 2 2 2 0 BED zinc finger zf-ISL3 PF14690.1 KFP06794.1 - 0.044 13.8 4.0 1.4 8.9 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2256 PF10013.4 KFP06794.1 - 0.046 13.4 0.7 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_5 PF14634.1 KFP06794.1 - 0.065 12.9 1.3 0.62 9.8 0.9 2.0 1 1 0 1 1 1 0 zinc-RING finger domain FYVE PF01363.16 KFP06794.1 - 0.086 12.7 1.2 0.21 11.5 0.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger LIM PF00412.17 KFP06794.1 - 0.089 12.8 0.5 0.62 10.1 0.3 1.9 1 1 0 1 1 1 0 LIM domain zf-RING_2 PF13639.1 KFP06794.1 - 0.1 12.4 1.7 0.41 10.5 1.3 1.8 1 1 1 2 2 2 0 Ring finger domain zf-IS66 PF13005.2 KFP06794.1 - 0.1 12.5 1.5 9.5 6.2 0.1 2.4 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 RRN7 PF11781.3 KFP06794.1 - 0.12 11.8 0.6 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-met2 PF12907.2 KFP06794.1 - 0.12 12.3 2.2 0.21 11.5 0.4 2.0 2 0 0 2 2 2 0 Zinc-binding GAGA PF09237.6 KFP06794.1 - 0.16 11.5 0.9 0.19 11.3 0.5 1.4 1 1 0 1 1 1 0 GAGA factor FYDLN_acid PF09538.5 KFP06794.1 - 0.17 12.4 0.8 3.4 8.3 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_4 PF14570.1 KFP06794.1 - 0.24 11.0 2.5 0.82 9.3 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2HC_2 PF13913.1 KFP06794.1 - 0.26 10.9 4.2 6.8 6.4 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFP06794.1 - 0.37 10.8 6.0 1 9.3 0.1 2.1 2 0 0 2 2 2 0 zinc-finger TF_Zn_Ribbon PF08271.7 KFP06794.1 - 0.49 9.7 3.1 8.9 5.7 0.3 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding NADH-G_4Fe-4S_3 PF10588.4 KFP06794.1 - 1.3 8.2 3.4 0.36 10.1 0.2 1.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1610 PF07754.6 KFP06794.1 - 7.3 6.8 6.6 18 5.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) SAND PF01342.16 KFP06795.1 - 4.3e-35 119.2 0.1 8.1e-35 118.4 0.1 1.4 1 0 0 1 1 1 1 SAND domain DUF948 PF06103.6 KFP06795.1 - 0.0029 17.4 3.0 0.0029 17.4 2.1 2.4 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF948) YTH PF04146.10 KFP06796.1 - 1.8e-47 160.4 0.0 2.7e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain DUF4106 PF13388.1 KFP06796.1 - 1.6 7.5 8.2 2.7 6.8 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PMSR PF01625.16 KFP06797.1 - 5.4e-17 62.1 0.1 6.1e-17 61.9 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Metal_resist PF13801.1 KFP06797.1 - 0.021 14.8 2.1 0.028 14.4 1.4 1.1 1 0 0 1 1 1 0 Heavy-metal resistance UcrQ PF02939.11 KFP06797.1 - 0.026 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 UcrQ family HLH PF00010.21 KFP06798.1 - 5.1e-12 45.3 0.0 7.3e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain E2F_TDP PF02319.15 KFP06799.1 - 2.9e-24 84.4 0.1 4.5e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Caps_synth_GfcC PF06251.6 KFP06799.1 - 0.1 11.7 0.5 0.16 11.1 0.3 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC TFIIS_M PF07500.9 KFP06800.1 - 2.3e-34 117.8 0.5 2.9e-34 117.5 0.4 1.3 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KFP06800.1 - 1.1e-18 66.5 7.2 2.3e-18 65.5 5.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KFP06800.1 - 1e-15 56.9 0.7 2.7e-15 55.6 0.5 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain 7tm_1 PF00001.16 KFP06801.1 - 3.5e-61 206.5 17.2 4.1e-61 206.3 11.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 KFP06801.1 - 1.5e-06 27.5 10.3 0.00066 18.9 0.7 2.1 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srsx PF10320.4 KFP06801.1 - 0.00046 19.4 15.0 0.04 13.0 10.4 2.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srw PF10324.4 KFP06801.1 - 0.0013 17.9 12.4 0.0039 16.3 8.5 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw SYS1 PF09801.4 KFP06801.1 - 0.039 13.9 0.6 0.039 13.9 0.4 2.4 2 1 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network Herpes_US9 PF06072.6 KFP06801.1 - 0.14 11.9 0.2 0.14 11.9 0.1 2.9 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 RCC1 PF00415.13 KFP06802.1 - 3.6e-49 164.7 9.6 3.2e-12 46.4 0.2 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFP06802.1 - 6.6e-15 54.2 21.5 0.0035 16.9 1.5 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat CorA PF01544.13 KFP06804.1 - 0.065 12.2 3.0 0.094 11.7 1.9 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 KFP06804.1 - 0.3 10.9 1.8 0.55 10.0 1.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 KFP06804.1 - 1.1 9.0 17.5 2.7 7.7 12.1 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.1 KFP06804.1 - 1.9 7.6 24.2 0.32 10.1 11.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 KFP06804.1 - 2.6 7.6 15.8 0.35 10.5 6.1 2.2 2 0 0 2 2 2 0 Mnd1 family DUF3552 PF12072.3 KFP06804.1 - 5.2 6.2 21.0 0.33 10.1 10.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) TPR_MLP1_2 PF07926.7 KFP06804.1 - 8.4 6.1 25.1 8.3 6.1 1.1 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_C1 PF00112.18 KFP06805.1 - 7.6e-72 241.7 5.0 9.4e-72 241.4 3.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KFP06805.1 - 1.5e-09 37.9 0.2 2.6e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KFP06805.1 - 0.002 16.7 0.4 0.13 10.7 0.2 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Pkinase_Tyr PF07714.12 KFP06806.1 - 2.5e-93 311.8 0.0 3.2e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06806.1 - 9.6e-50 169.1 0.0 1.3e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP06806.1 - 3.6e-27 93.9 0.2 8.2e-27 92.8 0.1 1.7 2 0 0 2 2 2 1 SH2 domain SH3_9 PF14604.1 KFP06806.1 - 0.00024 20.5 0.1 0.00067 19.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.18 KFP06806.1 - 0.00063 19.5 0.0 0.039 13.6 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family SH3_1 PF00018.23 KFP06806.1 - 0.0017 17.7 0.3 0.0073 15.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFP06806.1 - 0.0023 17.3 0.4 0.0053 16.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain WH2 PF02205.15 KFP06807.1 - 1.9e-08 33.6 0.0 3.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 WH2 motif 7tm_1 PF00001.16 KFP06808.1 - 9.4e-40 136.3 20.6 1.4e-39 135.7 14.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) UPF0197 PF05251.7 KFP06808.1 - 4.1 7.7 10.5 0.54 10.5 0.3 3.5 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0197) C2 PF00168.25 KFP06809.1 - 4.6e-35 119.3 0.1 2.7e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 C2 domain DUF778 PF05608.7 KFP06810.1 - 4.5e-41 139.9 2.0 4.3e-40 136.8 1.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF778) CTX_RstB PF07459.6 KFP06810.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 CTX phage RstB protein WD40 PF00400.27 KFP06812.1 - 1.9e-34 116.2 3.6 7.4e-08 31.9 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat TPR_11 PF13414.1 KFP06812.1 - 6.8e-17 60.8 11.2 5.8e-14 51.4 2.9 2.5 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 KFP06812.1 - 1.4e-07 31.1 1.4 0.0057 16.7 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP06812.1 - 5.6e-07 29.8 0.7 0.0057 16.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFP06812.1 - 5e-06 26.0 9.0 0.042 13.7 0.3 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFP06812.1 - 1.2e-05 24.6 10.4 0.11 12.1 0.6 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP06812.1 - 1.7e-05 25.3 2.4 0.02 15.5 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP06812.1 - 3.2e-05 24.1 0.7 0.16 12.6 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP06812.1 - 6.2e-05 23.0 4.6 0.00012 22.1 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFP06812.1 - 0.00018 21.7 0.3 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFP06812.1 - 0.18 11.7 2.2 0.26 11.1 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.16 KFP06813.1 - 3.7e-82 275.8 43.5 4.3e-82 275.6 30.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family OprF PF05736.6 KFP06813.1 - 0.064 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 OprF membrane domain DUF1419 PF07215.6 KFP06813.1 - 0.25 11.2 2.0 3.7 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) DUF1693 PF07984.7 KFP06814.1 - 3e-161 535.9 2.2 3.4e-161 535.7 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1693) DUF4656 PF15551.1 KFP06815.1 - 1.1e-139 465.7 20.0 5.9e-105 351.4 4.4 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4656) CS PF04969.11 KFP06816.1 - 1.5e-18 67.0 0.1 5.1e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.1 KFP06816.1 - 2.7e-10 40.0 1.2 7.1e-10 38.6 0.8 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. ATP-synt_E PF05680.7 KFP06816.1 - 5.7 6.9 13.3 22 5.1 9.2 2.0 1 0 0 1 1 1 0 ATP synthase E chain Hormone_recep PF00104.25 KFP06817.1 - 1e-22 80.2 0.1 1.5e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor G-patch PF01585.18 KFP06818.1 - 2.3e-08 33.6 1.1 2.3e-08 33.6 0.8 1.6 2 0 0 2 2 2 1 G-patch domain Ribosomal_60s PF00428.14 KFP06818.1 - 0.14 12.5 9.9 0.29 11.5 6.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein 14-3-3 PF00244.15 KFP06819.1 - 1.8e-106 354.5 6.9 2e-106 354.4 4.8 1.0 1 0 0 1 1 1 1 14-3-3 protein His_Phos_2 PF00328.17 KFP06819.1 - 0.011 15.0 0.4 0.012 14.9 0.3 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) TMCO5 PF14992.1 KFP06819.1 - 0.03 13.4 2.5 0.038 13.1 1.7 1.3 1 0 0 1 1 1 0 TMCO5 family DUF837 PF05769.6 KFP06819.1 - 0.069 12.6 4.2 0.11 12.0 0.3 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF837) FliM PF02154.10 KFP06819.1 - 0.091 12.4 0.0 0.29 10.7 0.0 1.7 1 1 1 2 2 2 0 Flagellar motor switch protein FliM CCDC-167 PF15188.1 KFP06819.1 - 0.12 12.3 0.8 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-DHHC PF01529.15 KFP06820.1 - 5.8e-39 133.2 4.8 5.8e-39 133.2 3.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 KFP06820.1 - 0.55 9.6 8.7 0.27 10.6 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Mannosyl_trans2 PF04188.8 KFP06821.1 - 1.8e-130 435.8 4.5 2.3e-130 435.5 3.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3518 PF12031.3 KFP06822.1 - 8.4e-144 477.0 0.1 1.6e-143 476.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3518) ARID PF01388.16 KFP06822.1 - 1.1e-24 86.1 0.0 2.7e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Sigma70_ner PF04546.8 KFP06822.1 - 0.24 10.9 4.3 0.51 9.9 3.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region alpha-hel2 PF14456.1 KFP06822.1 - 0.32 9.6 1.8 0.57 8.8 1.2 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Pkinase PF00069.20 KFP06823.1 - 1e-147 490.2 0.0 9.2e-75 251.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06823.1 - 4.3e-78 261.9 0.0 7.1e-41 139.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFP06823.1 - 2.3e-15 56.3 0.0 1.2e-07 31.0 0.0 3.5 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 KFP06823.1 - 2.1e-10 40.0 0.0 5.7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFP06823.1 - 1.2e-05 24.7 0.0 0.008 15.5 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL APH PF01636.18 KFP06823.1 - 3.1e-05 23.8 0.0 0.21 11.3 0.0 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family tRNA-synt_1f PF01921.13 KFP06823.1 - 0.00059 18.6 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) RIO1 PF01163.17 KFP06823.1 - 0.012 14.9 0.0 0.41 9.9 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Pkinase_C PF00433.19 KFP06823.1 - 0.016 15.6 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Choline_kinase PF01633.15 KFP06823.1 - 0.12 11.9 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase HMG14_17 PF01101.13 KFP06824.1 - 5e-21 75.1 21.6 5.7e-21 75.0 15.0 1.0 1 0 0 1 1 1 1 HMG14 and HMG17 TT_ORF2 PF02957.10 KFP06824.1 - 7 7.3 7.8 8.2 7.1 5.4 1.3 1 0 0 1 1 1 0 TT viral ORF2 Prenyltransf PF01255.14 KFP06825.1 - 4.7e-83 277.7 0.2 6.1e-83 277.3 0.1 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RecX PF02631.11 KFP06825.1 - 0.45 10.7 7.2 1.6 8.9 0.1 2.5 2 1 0 2 2 2 0 RecX family CSD PF00313.17 KFP06826.1 - 1.6e-17 63.0 0.3 4e-17 61.7 0.2 1.7 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain zf-CCHC PF00098.18 KFP06826.1 - 1.1e-06 28.2 11.2 6.2e-05 22.7 2.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KFP06826.1 - 5.8e-05 22.6 10.6 0.036 13.7 0.9 2.5 2 0 0 2 2 2 2 Zinc knuckle Viral_NABP PF05515.6 KFP06826.1 - 0.33 11.2 2.8 0.61 10.3 1.9 1.5 1 0 0 1 1 1 0 Viral nucleic acid binding zf-CCHC_6 PF15288.1 KFP06826.1 - 0.66 9.6 7.2 7 6.4 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 KFP06826.1 - 3.8 7.0 10.6 0.4 10.2 3.8 2.0 1 1 1 2 2 2 0 Zinc knuckle Crystall PF00030.14 KFP06827.1 - 3.5e-134 436.9 0.1 4.7e-25 87.2 0.0 6.2 6 0 0 6 6 6 6 Beta/Gamma crystallin Crystall_3 PF08964.5 KFP06827.1 - 4e-07 29.6 0.1 9.6 6.0 0.0 6.8 8 0 0 8 8 8 2 Beta/Gamma crystallin Ricin_B_lectin PF00652.17 KFP06827.1 - 4.3e-07 30.0 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KFP06827.1 - 0.008 16.5 0.0 0.029 14.7 0.0 1.9 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like SEP PF08059.8 KFP06828.1 - 3.3e-17 62.5 0.3 7.6e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KFP06828.1 - 7.6e-10 38.7 0.0 7e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 UBX domain Abhydrolase_4 PF08386.5 KFP06828.1 - 0.058 13.2 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein Nup54 PF13874.1 KFP06828.1 - 0.11 12.1 4.1 0.26 10.9 2.8 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF2730 PF10805.3 KFP06828.1 - 0.14 11.9 4.7 0.35 10.6 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.10 KFP06828.1 - 0.41 10.1 4.4 1.1 8.8 3.1 1.7 1 0 0 1 1 1 0 Septum formation initiator TMPIT PF07851.8 KFP06828.1 - 0.46 9.4 2.5 0.67 8.9 1.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.7 KFP06828.1 - 1.9 8.2 4.8 4.1 7.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) XhlA PF10779.4 KFP06828.1 - 3.2 7.7 9.3 9.7 6.1 6.4 1.9 1 1 0 1 1 1 0 Haemolysin XhlA IncA PF04156.9 KFP06828.1 - 7.1 6.1 10.1 14 5.2 7.0 1.5 1 0 0 1 1 1 0 IncA protein SH3BGR PF04908.10 KFP06829.1 - 6.5e-38 128.6 0.0 7.4e-38 128.4 0.0 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KFP06829.1 - 1.7e-07 31.1 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Reo_sigmaC PF04582.7 KFP06830.1 - 0.39 9.8 16.3 0.083 12.0 1.8 3.3 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Gtr1_RagA PF04670.7 KFP06832.1 - 3.5e-63 212.8 2.5 4.6e-63 212.4 1.8 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KFP06832.1 - 0.019 14.1 0.1 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family TSC22 PF01166.13 KFP06833.1 - 0.0028 17.5 1.7 0.0039 17.1 1.2 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family HALZ PF02183.13 KFP06833.1 - 0.02 14.5 0.7 0.037 13.7 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF904 PF06005.7 KFP06833.1 - 0.029 14.6 2.4 0.044 14.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 KFP06833.1 - 0.13 12.5 1.0 0.88 9.9 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Connexin PF00029.14 KFP06834.1 - 2.1e-49 166.0 0.2 3.2e-49 165.4 0.1 1.2 1 0 0 1 1 1 1 Connexin Connexin_CCC PF10582.4 KFP06834.1 - 3.6e-24 84.3 0.2 9e-24 83.0 0.1 1.7 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain CemA PF03040.9 KFP06834.1 - 6.4 6.3 6.4 9.1 5.8 0.0 2.5 3 0 0 3 3 3 0 CemA family zf-C2H2_jaz PF12171.3 KFP06835.1 - 1.8e-09 37.4 3.8 2.5e-09 36.9 2.7 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP06835.1 - 0.00072 19.6 0.1 0.00092 19.2 0.1 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFP06835.1 - 0.0051 16.9 1.5 0.0071 16.5 1.1 1.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 KFP06835.1 - 0.017 14.9 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.20 KFP06837.1 - 5.1e-53 179.8 0.1 3.5e-52 177.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06837.1 - 3.8e-33 114.6 0.4 5.2e-23 81.4 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KFP06837.1 - 0.0044 16.7 0.1 0.022 14.4 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFP06837.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFP06837.1 - 0.056 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KFP06837.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-C3HC4_2 PF13923.1 KFP06838.1 - 7.5e-10 38.6 6.2 7.5e-10 38.6 4.3 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFP06838.1 - 8.4e-10 38.2 2.8 2.6e-09 36.6 1.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFP06838.1 - 9e-09 35.0 5.3 9e-09 35.0 3.7 2.4 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFP06838.1 - 2.5e-08 33.4 3.4 2.5e-08 33.4 2.4 2.8 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP06838.1 - 2.8e-07 30.1 4.8 2.8e-07 30.1 3.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP06838.1 - 3.7e-07 29.7 4.4 3.7e-07 29.7 3.1 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP06838.1 - 2.5e-06 27.2 7.1 2.5e-06 27.2 4.9 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.19 KFP06838.1 - 5.1e-06 26.2 6.6 5.1e-06 26.2 4.6 3.6 4 0 0 4 4 4 1 B-box zinc finger zf-RING_6 PF14835.1 KFP06838.1 - 0.0002 21.0 0.2 0.0002 21.0 0.2 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF745 PF05335.8 KFP06838.1 - 0.0018 17.8 3.4 0.037 13.5 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF745) DUF1664 PF07889.7 KFP06838.1 - 0.081 12.7 0.5 0.2 11.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF641 PF04859.7 KFP06838.1 - 0.22 11.2 2.6 0.4 10.4 1.8 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-MIZ PF02891.15 KFP06838.1 - 0.6 9.6 9.8 5.2 6.6 6.8 2.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Cation_efflux PF01545.16 KFP06839.1 - 6.7e-18 64.7 1.6 7.6e-18 64.5 1.1 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1275 PF06912.6 KFP06839.1 - 0.0046 16.1 0.3 0.0049 16.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3353 PF11833.3 KFP06839.1 - 0.043 13.2 0.5 0.054 12.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Glyco_transf_64 PF09258.5 KFP06840.1 - 2e-79 266.2 0.0 2.3e-78 262.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.10 KFP06840.1 - 8.9e-58 195.7 0.0 1.2e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Exostosin family PAF-AH_p_II PF03403.8 KFP06841.1 - 2.4e-139 463.8 0.0 2.7e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFP06841.1 - 2e-17 63.3 0.0 3.2e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP06841.1 - 1.4e-10 41.4 0.0 1.8e-08 34.5 0.0 2.5 2 1 1 3 3 3 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFP06841.1 - 7.1e-07 28.3 0.0 4.2e-06 25.8 0.0 2.1 2 1 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFP06841.1 - 1.2e-05 24.2 0.2 0.02 13.7 0.0 2.7 3 0 0 3 3 3 2 Chlorophyllase Peptidase_S9 PF00326.16 KFP06841.1 - 1.3e-05 24.5 0.0 3.5e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KFP06841.1 - 0.0002 20.8 0.0 0.00048 19.6 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 KFP06841.1 - 0.0072 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFP06841.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 KFP06841.1 - 0.012 15.0 0.0 0.22 10.9 0.0 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.13 KFP06841.1 - 0.022 14.0 0.0 0.044 13.0 0.0 1.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KFP06841.1 - 0.027 14.0 0.0 0.06 12.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFP06841.1 - 0.13 12.1 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_8 PF06259.7 KFP06841.1 - 0.16 11.4 0.0 0.42 10.0 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase HlyIII PF03006.15 KFP06842.1 - 1.7e-42 145.3 13.1 2.7e-42 144.6 9.1 1.3 1 0 0 1 1 1 1 Haemolysin-III related Mito_fiss_reg PF05308.6 KFP06843.1 - 4e-83 278.6 2.1 4.7e-83 278.4 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial fission regulator EF-hand_7 PF13499.1 KFP06844.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP06844.1 - 0.023 13.9 0.0 0.064 12.5 0.0 1.8 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.4 KFP06844.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_6 PF13405.1 KFP06844.1 - 0.035 13.9 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain PID PF00640.18 KFP06846.1 - 7.4e-15 55.1 0.0 8.7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PID_2 PF14719.1 KFP06846.1 - 1.8e-12 47.2 0.0 2e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PTB PF08416.8 KFP06846.1 - 5.3e-07 29.6 0.0 7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine-binding domain MIF PF01187.13 KFP06846.1 - 0.091 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Macoilin PF09726.4 KFP06847.1 - 4.2e-294 977.2 16.9 4.8e-294 977.0 11.7 1.0 1 0 0 1 1 1 1 Transmembrane protein Reo_sigmaC PF04582.7 KFP06847.1 - 0.0032 16.6 8.5 0.11 11.6 0.9 2.3 2 0 0 2 2 2 2 Reovirus sigma C capsid protein FtsQ PF03799.10 KFP06847.1 - 0.52 10.5 7.0 4.6 7.4 0.0 3.7 3 2 1 4 4 4 0 Cell division protein FtsQ Mto2_bdg PF12808.2 KFP06847.1 - 2.4 8.3 20.7 1.6 8.8 1.3 4.4 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region V_ATPase_I PF01496.14 KFP06847.1 - 2.7 5.7 29.0 1.5 6.5 18.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 KFP06847.1 - 5.3 7.0 18.7 3.9 7.4 2.4 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.7 KFP06847.1 - 7.2 6.6 14.1 5.4 7.0 0.3 5.7 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat IncA PF04156.9 KFP06847.1 - 7.6 6.0 50.7 4.6 6.7 16.2 4.3 2 1 2 4 4 4 0 IncA protein ApoO PF09769.4 KFP06847.1 - 9.6 5.8 12.8 0.35 10.5 0.7 3.4 1 1 1 2 2 2 0 Apolipoprotein O Ammonium_transp PF00909.16 KFP06848.1 - 3.9e-46 157.3 23.0 4.6e-46 157.0 16.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TH1 PF04858.8 KFP06848.1 - 0.17 10.0 0.1 0.24 9.5 0.0 1.1 1 0 0 1 1 1 0 TH1 protein UPF0220 PF05255.6 KFP06849.1 - 9.2e-51 171.3 4.9 1e-50 171.2 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4064 PF13273.1 KFP06849.1 - 0.26 11.3 2.8 0.8 9.8 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SYF2 PF08231.7 KFP06851.1 - 4.4e-53 179.5 10.7 4.4e-53 179.5 7.4 1.4 2 0 0 2 2 2 1 SYF2 splicing factor FUSC-like PF12805.2 KFP06851.1 - 0.00072 18.5 0.3 0.001 18.0 0.2 1.2 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS rve_3 PF13683.1 KFP06851.1 - 0.044 13.3 0.3 0.87 9.1 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain ARD PF03079.9 KFP06851.1 - 8.5 6.3 10.7 0.85 9.5 0.7 2.4 1 1 2 3 3 3 0 ARD/ARD' family Runt PF00853.14 KFP06852.1 - 4.2e-53 178.4 0.4 6.2e-53 177.8 0.3 1.3 1 0 0 1 1 1 1 Runt domain RunxI PF08504.6 KFP06852.1 - 2e-46 156.5 6.3 2e-46 156.5 4.4 1.9 2 0 0 2 2 2 1 Runx inhibition domain GST_N_3 PF13417.1 KFP06854.1 - 1.6e-07 31.4 0.0 3.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFP06854.1 - 5.5e-05 22.9 0.0 9.3e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFP06854.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFP06854.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFP06854.1 - 0.0035 17.2 0.3 0.032 14.2 0.1 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PWI PF01480.12 KFP06855.1 - 1.6e-30 105.0 0.1 3.4e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 PWI domain DUF2976 PF11190.3 KFP06856.1 - 0.00068 19.1 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2976) Shisa PF13908.1 KFP06856.1 - 0.018 15.1 0.3 0.021 15.0 0.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CbtB PF09489.5 KFP06856.1 - 0.019 14.8 0.4 0.032 14.1 0.3 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Adeno_E3_CR2 PF02439.10 KFP06856.1 - 0.019 14.4 1.8 0.027 14.0 1.2 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3609 PF12259.3 KFP06856.1 - 0.034 12.8 0.0 0.039 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF1705 PF08019.7 KFP06856.1 - 0.042 13.3 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) Peptidase_M56 PF05569.6 KFP06856.1 - 0.046 12.6 0.0 0.046 12.6 0.0 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 SKG6 PF08693.5 KFP06856.1 - 0.047 13.0 1.3 0.082 12.2 0.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1049 PF06305.6 KFP06856.1 - 0.048 13.1 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1043 PF06295.7 KFP06856.1 - 0.095 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) m04gp34like PF12216.3 KFP06856.1 - 0.12 11.7 0.2 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Immune evasion protein EphA2_TM PF14575.1 KFP06856.1 - 0.14 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Fst_toxin PF13955.1 KFP06856.1 - 0.96 9.1 7.7 1.7 8.4 5.3 1.4 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system Calcipressin PF04847.7 KFP06857.1 - 1.1e-58 197.8 0.9 1.5e-58 197.4 0.6 1.2 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 KFP06857.1 - 0.0027 17.4 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mg_trans_NIPA PF05653.9 KFP06858.1 - 9.3e-70 234.9 19.4 1.2e-69 234.5 13.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA BatA PF07584.6 KFP06858.1 - 5.2 7.3 6.5 21 5.3 0.4 3.5 3 1 0 3 3 3 0 Aerotolerance regulator N-terminal CP2 PF04516.10 KFP06859.1 - 4.9e-80 268.0 0.1 6.9e-80 267.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tissue_fac PF01108.12 KFP06860.1 - 4e-23 81.2 0.1 7.4e-23 80.3 0.1 1.4 1 0 0 1 1 1 1 Tissue factor Interfer-bind PF09294.5 KFP06860.1 - 1.3e-08 34.8 1.7 1.9e-08 34.2 0.5 1.9 2 1 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III IL6Ra-bind PF09240.5 KFP06860.1 - 0.022 14.9 0.2 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding Tissue_fac PF01108.12 KFP06861.1 - 1e-22 79.8 0.1 1.1e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Tissue factor Pkinase_Tyr PF07714.12 KFP06862.1 - 1.1e-75 254.1 0.0 1.6e-75 253.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_lbd PF01404.14 KFP06862.1 - 4.1e-75 251.4 0.0 6.9e-75 250.7 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Pkinase PF00069.20 KFP06862.1 - 1.7e-28 99.4 0.0 3e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.16 KFP06862.1 - 1.7e-24 85.7 8.4 2.1e-12 46.9 2.2 3.5 3 1 0 3 3 3 2 Fibronectin type III domain EphA2_TM PF14575.1 KFP06862.1 - 1.2e-20 73.6 0.0 2.6e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SAM_1 PF00536.25 KFP06862.1 - 1.1e-17 63.8 0.0 2.1e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP06862.1 - 3.3e-15 55.6 0.0 9.3e-15 54.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SusE PF14292.1 KFP06862.1 - 1.7e-05 24.6 1.7 0.011 15.5 0.6 2.5 2 0 0 2 2 2 2 SusE outer membrane protein GCC2_GCC3 PF07699.8 KFP06862.1 - 0.0023 17.4 3.1 0.0023 17.4 2.1 2.9 3 0 0 3 3 3 1 GCC2 and GCC3 Interfer-bind PF09294.5 KFP06862.1 - 0.0025 17.8 0.2 0.024 14.6 0.5 2.2 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III SpoA PF01052.15 KFP06862.1 - 0.0068 15.9 0.0 6.2 6.4 0.0 2.9 3 0 0 3 3 3 2 Surface presentation of antigens (SPOA) CD34_antigen PF06365.7 KFP06862.1 - 0.022 14.3 0.0 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 CD34/Podocalyxin family Y_Y_Y PF07495.8 KFP06862.1 - 0.24 11.1 1.8 5.3 6.8 1.2 2.4 2 0 0 2 2 2 0 Y_Y_Y domain zf-H2C2_2 PF13465.1 KFP06863.1 - 3.5e-30 102.7 46.5 1.5e-08 34.5 0.3 7.3 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFP06863.1 - 2.8e-27 93.3 39.9 0.00015 21.9 1.0 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP06863.1 - 1e-18 66.2 35.0 0.0026 17.9 0.5 6.7 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP06863.1 - 5.4e-06 26.3 23.2 0.011 15.7 1.5 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding Marek_A PF02124.10 KFP06863.1 - 0.0061 16.0 1.4 0.76 9.1 0.1 3.1 2 1 1 3 3 3 1 Marek's disease glycoprotein A zf-met PF12874.2 KFP06863.1 - 0.077 13.2 0.5 0.077 13.2 0.4 5.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type Exo_endo_phos PF03372.18 KFP06864.1 - 1.3e-34 120.2 0.0 1.8e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 KFP06864.1 - 7.6e-27 93.7 0.0 1.8e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DUF3449 PF11931.3 KFP06865.1 - 1.7e-75 252.9 5.7 1.7e-75 252.9 4.0 2.3 2 2 1 3 3 3 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.1 KFP06865.1 - 8.9e-29 98.5 1.4 1.9e-28 97.4 1.0 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.3 KFP06865.1 - 2.7e-15 55.5 0.7 5.6e-15 54.5 0.5 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain MMR_HSR1_C PF08438.5 KFP06865.1 - 0.077 13.2 0.3 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 GTPase of unknown function C-terminal LIM PF00412.17 KFP06866.1 - 4.5e-48 161.1 72.1 3.1e-12 46.3 4.2 5.1 5 0 0 5 5 5 5 LIM domain Ureidogly_hydro PF04115.7 KFP06866.1 - 0.034 13.5 0.0 0.65 9.3 0.0 2.6 1 1 2 3 3 3 0 Ureidoglycolate hydrolase Utp11 PF03998.8 KFP06867.1 - 7.7e-56 189.6 19.6 8.6e-56 189.4 13.6 1.0 1 0 0 1 1 1 1 Utp11 protein GvpK PF05121.7 KFP06867.1 - 0.12 12.2 2.2 3.9 7.3 0.5 2.3 1 1 1 2 2 2 0 Gas vesicle protein K TPR_MLP1_2 PF07926.7 KFP06867.1 - 0.23 11.2 6.3 0.69 9.6 0.8 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Takusan PF04822.8 KFP06867.1 - 0.82 9.4 5.7 3 7.6 0.3 2.9 2 1 1 3 3 3 0 Takusan YebO PF13974.1 KFP06867.1 - 9.6 6.0 7.2 1.2 8.9 1.4 2.2 2 1 0 2 2 2 0 YebO-like protein dCMP_cyt_deam_1 PF00383.17 KFP06868.1 - 3.2e-18 65.2 0.4 3.1e-09 36.4 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Mo25 PF08569.6 KFP06869.1 - 9e-132 439.1 11.3 1e-131 438.9 7.9 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 KFP06869.1 - 0.0075 16.5 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats UME PF08064.8 KFP06869.1 - 0.043 13.7 1.1 0.19 11.6 0.1 2.6 2 2 1 3 3 3 0 UME (NUC010) domain HEAT PF02985.17 KFP06869.1 - 0.12 12.5 0.0 19 5.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat zf-HC5HC2H PF13771.1 KFP06870.1 - 8.2e-12 45.1 2.7 8.2e-12 45.1 1.9 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFP06870.1 - 1.5e-06 28.1 2.8 5.3e-06 26.3 1.9 2.0 1 1 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.24 KFP06870.1 - 0.045 13.4 0.8 0.045 13.4 0.6 2.9 3 0 0 3 3 3 0 PHD-finger RCC1 PF00415.13 KFP06871.1 - 8.4e-64 211.6 26.4 4.3e-16 58.8 1.9 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFP06871.1 - 1e-32 111.0 32.2 1.8e-10 40.1 0.2 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KFP06871.1 - 9.1e-22 77.1 0.9 8.1e-20 70.8 0.1 2.3 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 KFP06871.1 - 8.1e-06 25.6 1.2 0.011 15.6 0.1 3.1 2 1 0 2 2 2 2 BTB And C-terminal Kelch SUKH-3 PF14433.1 KFP06871.1 - 0.056 13.2 0.5 2.2 8.0 0.0 3.3 3 0 0 3 3 3 0 SUKH-3 immunity protein PQQ_3 PF13570.1 KFP06871.1 - 1.1 9.5 4.3 12 6.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain Arf PF00025.16 KFP06872.1 - 3.9e-52 176.0 0.0 4.5e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KFP06872.1 - 4e-10 38.9 0.0 3e-08 32.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KFP06872.1 - 1.7e-09 37.2 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06872.1 - 2.6e-09 37.6 0.0 3.4e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFP06872.1 - 7.2e-09 35.1 0.0 8.7e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFP06872.1 - 7.2e-06 25.3 0.0 8.9e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP06872.1 - 0.00023 21.0 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arm PF00514.18 KFP06873.1 - 4e-86 280.2 16.9 3.2e-13 48.9 0.3 9.7 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP06873.1 - 4.6e-23 81.2 0.1 6.5e-09 35.9 0.0 5.9 2 2 5 7 7 7 6 HEAT repeats HEAT PF02985.17 KFP06873.1 - 2.1e-18 64.6 7.9 0.0013 18.6 0.0 6.9 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.1 KFP06873.1 - 2.9e-18 65.7 1.9 2.5e-06 27.7 0.1 6.6 3 3 4 7 7 7 5 HEAT-like repeat Adaptin_N PF01602.15 KFP06873.1 - 4.8e-09 35.0 0.1 8.7e-09 34.2 0.1 1.3 1 1 0 1 1 1 1 Adaptin N terminal region IBB PF01749.15 KFP06873.1 - 3e-08 33.6 0.9 5.4e-08 32.9 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 KFP06873.1 - 7.3e-07 28.5 0.6 0.74 8.8 0.0 4.3 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.9 KFP06873.1 - 3e-05 23.3 0.4 0.0066 15.5 0.1 2.6 1 1 1 2 2 2 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFP06873.1 - 5.1e-05 21.7 0.3 0.012 13.8 0.0 3.0 2 2 0 3 3 3 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 KFP06873.1 - 0.0004 20.2 0.5 6.5 6.7 0.0 4.2 4 1 1 5 5 5 1 V-ATPase subunit H Cnd3 PF12719.2 KFP06873.1 - 0.0099 14.8 0.1 1.3 7.8 0.0 3.4 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF1981 PF09324.5 KFP06873.1 - 0.02 14.3 0.7 0.59 9.7 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) Mo25 PF08569.6 KFP06873.1 - 0.022 13.8 0.1 0.063 12.2 0.0 1.8 1 0 0 1 1 1 0 Mo25-like RasGEF_N_2 PF14663.1 KFP06873.1 - 0.057 13.3 0.0 0.61 10.0 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RuvA_C PF07499.8 KFP06873.1 - 6.1 7.0 6.0 34 4.7 0.0 4.3 5 0 0 5 5 5 0 RuvA, C-terminal domain SPRY PF00622.23 KFP06875.1 - 3.8e-12 46.3 0.0 4.8e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 SPRY domain IMS_HHH PF11798.3 KFP06875.1 - 0.15 12.1 0.0 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 IMS family HHH motif BTB_2 PF02214.17 KFP06876.1 - 3.2e-18 65.7 0.2 7.1e-18 64.6 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain DUF4286 PF14114.1 KFP06876.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) RNase_H2-Ydr279 PF09468.5 KFP06877.1 - 1.1e-49 169.2 0.3 1.5e-49 168.8 0.2 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF4057 PF13266.1 KFP06877.1 - 0.058 12.8 0.2 0.078 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) FAM124 PF15067.1 KFP06878.1 - 1.4e-113 378.1 0.0 2e-113 377.6 0.0 1.2 1 0 0 1 1 1 1 FAM124 family Serpin PF00079.15 KFP06879.1 - 4.4e-91 305.7 1.7 5e-91 305.6 1.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) WD40 PF00400.27 KFP06880.1 - 1.4e-32 110.4 10.1 1.7e-10 40.3 1.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat FYVE PF01363.16 KFP06880.1 - 2.6e-15 56.0 8.2 5.9e-15 54.9 5.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger Nucleoporin_N PF08801.6 KFP06880.1 - 1.9e-07 30.2 0.2 0.077 11.7 0.0 3.7 2 1 1 4 4 4 2 Nup133 N terminal like FYVE_2 PF02318.11 KFP06880.1 - 0.061 13.2 4.8 0.14 12.0 3.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.19 KFP06880.1 - 1.2 9.0 9.7 0.16 11.9 0.4 3.3 3 0 0 3 3 3 0 B-box zinc finger DiS_P_DiS PF06750.8 KFP06880.1 - 3.4 7.5 6.4 32 4.3 4.0 2.8 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain adh_short PF00106.20 KFP06881.1 - 3.2e-20 72.7 0.0 5.4e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP06881.1 - 8.7e-11 41.8 0.2 1.7e-10 40.8 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFP06881.1 - 3.4e-09 36.4 0.0 4.3e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFP06881.1 - 4e-08 33.3 0.0 7.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFP06881.1 - 3.4e-06 27.1 1.7 0.00096 19.1 0.2 2.9 2 1 1 3 3 3 2 NADH(P)-binding DUF1776 PF08643.5 KFP06881.1 - 7.4e-05 22.0 0.1 0.0054 15.9 0.1 2.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 KFP06881.1 - 0.093 11.6 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KFP06881.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hydrolase PF00702.21 KFP06882.1 - 9.4e-74 248.4 1.1 3.3e-73 246.6 0.9 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFP06882.1 - 2e-62 207.2 0.1 6.1e-11 42.2 0.0 6.6 6 0 0 6 6 6 6 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 KFP06882.1 - 7.5e-48 162.5 2.7 2.3e-47 160.9 1.8 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFP06882.1 - 4.4e-15 56.3 0.0 1.1e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFP06882.1 - 1.9e-07 30.9 2.3 5.1e-05 22.9 0.3 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KFP06882.1 - 0.00072 19.4 0.9 0.0095 15.8 0.1 2.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Toxin_63 PF15541.1 KFP06882.1 - 0.0056 16.6 0.0 1.7 8.6 0.0 2.8 2 0 0 2 2 2 1 Putative toxin 63 SapB_2 PF03489.12 KFP06882.1 - 0.074 13.0 0.6 0.39 10.7 0.1 2.5 3 0 0 3 3 3 0 Saposin-like type B, region 2 DUF2200 PF09966.4 KFP06882.1 - 0.16 11.8 2.8 7.9 6.3 0.0 3.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2200) Glycos_transf_1 PF00534.15 KFP06883.1 - 1.5e-27 96.0 0.0 3e-27 95.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFP06883.1 - 9.1e-11 42.0 0.0 6.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFP06883.1 - 2.8e-05 24.3 0.0 4.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFP06883.1 - 0.0056 16.4 0.0 0.28 10.8 0.0 2.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Pkinase PF00069.20 KFP06884.1 - 1.7e-59 201.1 0.1 2.7e-59 200.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06884.1 - 2.6e-42 144.6 0.0 4.2e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06884.1 - 4.7e-07 29.0 0.0 7.6e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF2924 PF11149.3 KFP06885.1 - 2.4 8.1 9.0 25 4.8 6.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) CKAP2_C PF15297.1 KFP06886.1 - 4.1e-72 242.9 31.0 3.2e-49 167.6 3.6 3.3 2 1 1 3 3 3 2 Cytoskeleton-associated protein 2 C-terminus EAP30 PF04157.11 KFP06887.1 - 1.5e-58 197.6 3.8 3.1e-58 196.5 1.8 1.9 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KFP06887.1 - 3.5e-15 55.5 0.0 7e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KFP06887.1 - 0.0082 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF1448 PF07289.6 KFP06887.1 - 0.013 14.4 0.1 0.048 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1448) MA3 PF02847.12 KFP06887.1 - 0.04 13.6 0.9 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 MA3 domain Glyco_transf_8 PF01501.15 KFP06887.1 - 0.04 13.2 0.0 0.4 9.9 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferase family 8 RPW8 PF05659.6 KFP06887.1 - 0.072 12.6 1.1 0.13 11.7 0.8 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fib_alpha PF08702.5 KFP06887.1 - 0.086 12.9 0.4 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4319 PF14203.1 KFP06887.1 - 2 8.0 5.4 0.84 9.2 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) TSP_1 PF00090.14 KFP06888.1 - 5.7e-11 42.3 7.5 2.2e-10 40.4 5.2 2.1 1 0 0 1 1 1 1 Thrombospondin type 1 domain Fibrinogen_C PF00147.13 KFP06889.1 - 4.6e-60 203.1 9.4 5.1e-60 203.0 6.5 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4250 PF14056.1 KFP06890.1 - 0.29 10.9 2.3 0.45 10.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) PTEN_C2 PF10409.4 KFP06891.1 - 4.3e-16 58.8 0.5 1.8e-15 56.8 0.1 2.1 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 KFP06891.1 - 1.5e-09 37.5 0.0 6e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Ion_trans PF00520.26 KFP06891.1 - 2.5e-07 30.1 8.2 4.5e-07 29.3 5.3 1.6 1 1 0 1 1 1 1 Ion transport protein Y_phosphatase PF00102.22 KFP06891.1 - 5.4e-06 25.9 0.0 1.4e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFP06891.1 - 6.5e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 1 0 1 1 1 1 Inositol hexakisphosphate PKD_channel PF08016.7 KFP06891.1 - 0.017 13.5 3.8 0.027 12.9 2.6 1.3 1 0 0 1 1 1 0 Polycystin cation channel Y_phosphatase3 PF13350.1 KFP06891.1 - 0.019 15.1 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Mito_carr PF00153.22 KFP06892.1 - 8e-61 201.7 7.7 3.8e-20 71.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MRP-S31 PF15433.1 KFP06893.1 - 6.5e-67 226.0 6.8 7.1e-67 225.9 4.7 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Sulfatase PF00884.18 KFP06894.1 - 4.4e-13 49.1 0.1 4.7e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFP06894.1 - 1.3e-07 31.3 0.0 1.3e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 KFP06894.1 - 0.0016 17.3 0.0 0.0016 17.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Amino_oxidase PF01593.19 KFP06895.1 - 1.6e-79 268.0 0.0 3.2e-79 267.1 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFP06895.1 - 1.4e-14 53.8 0.6 3.4e-14 52.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFP06895.1 - 3.5e-06 26.1 0.0 9.2e-06 24.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFP06895.1 - 1.3e-05 24.2 0.9 1.9e-05 23.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KFP06895.1 - 1.6e-05 25.0 0.2 3.2e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFP06895.1 - 0.00081 19.7 1.8 0.0029 17.9 0.5 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFP06895.1 - 0.0022 17.8 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFP06895.1 - 0.0035 16.4 1.4 0.0092 15.0 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KFP06895.1 - 0.0055 15.2 0.4 0.013 13.9 0.3 1.7 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KFP06895.1 - 0.014 14.5 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 KFP06895.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KFP06895.1 - 0.015 15.0 0.5 0.052 13.3 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 KFP06895.1 - 0.028 13.2 0.3 0.044 12.6 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KFP06895.1 - 0.042 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KFP06895.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMO-like PF00743.14 KFP06895.1 - 0.15 10.2 0.0 0.22 9.6 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like ThiF PF00899.16 KFP06895.1 - 0.16 11.7 0.1 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 KFP06895.1 - 0.16 10.8 0.8 0.44 9.4 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein 7tm_1 PF00001.16 KFP06896.1 - 6.2e-83 277.8 13.2 7.7e-83 277.5 9.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06896.1 - 3.7e-17 62.3 7.8 6.8e-17 61.4 5.4 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP06896.1 - 2.4e-05 23.5 11.0 2.4e-05 23.5 7.6 2.0 3 0 0 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Srx COX6B PF02297.12 KFP06897.1 - 1.2e-18 66.8 5.4 1.4e-18 66.6 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KFP06897.1 - 0.0052 16.7 1.2 0.019 14.9 0.9 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 KFP06897.1 - 0.094 12.6 2.4 0.33 10.9 1.5 1.9 1 1 1 2 2 2 0 CHCH domain EamA PF00892.15 KFP06898.1 - 2.6e-07 30.7 2.6 2.6e-07 30.7 1.8 3.9 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 KFP06898.1 - 5.1e-07 29.8 3.2 5.1e-07 29.8 2.2 4.0 2 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 KFP06898.1 - 1.2e-06 28.2 0.5 1.2e-06 28.2 0.4 2.8 3 1 0 3 3 3 1 Triose-phosphate Transporter family DUF914 PF06027.7 KFP06898.1 - 4.7e-06 25.6 22.6 7.2e-06 25.0 15.6 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) Ion_trans_2 PF07885.11 KFP06899.1 - 5.9e-26 89.9 13.0 6.8e-17 60.9 3.0 2.3 2 0 0 2 2 2 2 Ion channel Ferric_reduct PF01794.14 KFP06899.1 - 0.028 14.4 2.7 0.045 13.8 1.9 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Bac_transf PF02397.11 KFP06899.1 - 0.88 8.6 2.7 1.7 7.7 1.1 1.9 2 0 0 2 2 2 0 Bacterial sugar transferase DUF2818 PF10993.3 KFP06899.1 - 0.94 10.0 6.0 0.48 10.9 1.7 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) VIT1 PF01988.14 KFP06899.1 - 2.2 7.6 4.6 0.65 9.4 0.7 1.8 1 1 1 2 2 2 0 VIT family Sulfotransfer_2 PF03567.9 KFP06900.1 - 2.2e-48 165.1 0.9 2.2e-48 165.1 0.6 1.4 2 0 0 2 2 2 1 Sulfotransferase family Toxin_43 PF15604.1 KFP06900.1 - 0.57 10.2 5.6 1 9.3 3.9 1.4 1 0 0 1 1 1 0 Putative toxin 43 zf-CCCH PF00642.19 KFP06901.1 - 1.3e-11 43.8 21.4 0.00052 19.6 0.3 4.7 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ras PF00071.17 KFP06902.1 - 9.3e-19 67.3 0.0 1e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 KFP06902.1 - 0.0029 17.0 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFP06902.1 - 0.003 16.8 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B TPP_enzyme_M PF00205.17 KFP06902.1 - 0.024 14.3 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain FERM_C PF09380.5 KFP06903.1 - 1e-26 92.9 0.4 2.1e-26 91.9 0.3 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFP06903.1 - 6.7e-15 55.3 0.3 1.1e-14 54.6 0.2 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFP06903.1 - 9.2e-14 51.2 0.1 9.2e-14 51.2 0.1 2.9 3 1 0 3 3 3 1 FERM N-terminal domain FA PF08736.6 KFP06903.1 - 6.6e-13 48.2 4.3 6.8e-13 48.1 1.8 2.0 2 0 0 2 2 2 1 FERM adjacent (FA) Pkinase PF00069.20 KFP06905.1 - 6.9e-72 241.7 0.0 8e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06905.1 - 2.9e-54 183.8 0.0 3.6e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06905.1 - 0.00019 20.4 0.0 0.0012 17.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP06905.1 - 0.0064 16.2 0.0 1.3 8.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF4288 PF14119.1 KFP06905.1 - 0.079 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) IL6Ra-bind PF09240.5 KFP06906.1 - 8.2e-18 64.4 0.3 1.5e-17 63.5 0.2 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFP06906.1 - 8.2e-07 28.9 0.4 1.8e-06 27.9 0.3 1.5 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Tissue_fac PF01108.12 KFP06906.1 - 8.1e-06 25.5 2.2 0.0052 16.5 0.1 2.3 2 0 0 2 2 2 2 Tissue factor fn3 PF00041.16 KFP06906.1 - 0.00017 21.6 0.4 0.0045 17.0 0.1 2.5 2 1 0 2 2 2 1 Fibronectin type III domain TMEM154 PF15102.1 KFP06906.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DOCK-C2 PF14429.1 KFP06907.1 - 1.1e-56 191.3 0.2 5.4e-56 189.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 KFP06907.1 - 4.7e-33 112.9 2.9 1.6e-32 111.2 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) PH PF00169.24 KFP06907.1 - 3.5e-10 40.0 0.8 8.5e-10 38.7 0.5 1.7 1 0 0 1 1 1 1 PH domain WD40 PF00400.27 KFP06908.1 - 9.8e-36 120.3 5.6 6.2e-07 29.0 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFP06908.1 - 0.038 13.7 0.1 1.8 8.3 0.0 3.2 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Kelch_1 PF01344.20 KFP06909.1 - 1.3e-55 184.7 6.9 1.2e-11 43.9 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFP06909.1 - 5.4e-37 124.4 2.3 1e-06 28.6 0.1 6.6 2 1 4 6 6 6 6 Kelch motif BACK PF07707.10 KFP06909.1 - 2.2e-27 94.9 0.0 4.7e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 KFP06909.1 - 6.8e-25 87.2 0.3 3.7e-24 84.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFP06909.1 - 1.2e-24 85.7 2.6 0.00011 22.1 0.0 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP06909.1 - 1.3e-24 84.9 4.8 3.1e-05 23.5 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFP06909.1 - 9.8e-22 76.4 1.0 0.00078 19.1 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP06909.1 - 7.9e-12 44.8 14.2 0.0044 16.9 0.2 5.7 5 0 0 5 5 5 4 Kelch motif SNF PF00209.13 KFP06911.1 - 3.9e-185 616.2 40.5 4.9e-185 615.9 28.1 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Caveolin PF01146.12 KFP06911.1 - 1.8 8.1 11.1 0.04 13.5 1.9 2.4 2 0 0 2 2 2 0 Caveolin LRR_8 PF13855.1 KFP06912.1 - 2.2e-32 110.5 40.6 3.4e-14 52.3 5.6 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP06912.1 - 5.9e-20 70.4 49.4 5.5e-07 29.0 1.7 4.9 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP06912.1 - 3.2e-18 62.9 33.5 0.0032 17.2 0.1 7.3 7 0 0 7 7 7 7 Leucine Rich Repeat LRR_5 PF13306.1 KFP06912.1 - 5.1e-10 39.1 2.1 9.5e-07 28.5 0.6 2.0 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFP06912.1 - 6.3e-07 28.5 34.2 0.39 11.1 0.2 7.8 8 0 0 8 8 8 5 Leucine rich repeat LRR_6 PF13516.1 KFP06912.1 - 7.6e-05 22.3 34.3 0.68 10.1 0.4 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.1 KFP06912.1 - 0.0043 16.6 1.4 0.22 11.0 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat CH PF00307.26 KFP06913.1 - 8.3e-83 273.5 0.9 2.5e-22 78.9 0.0 4.7 5 0 0 5 5 5 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFP06913.1 - 1e-12 48.0 0.1 3.3e-12 46.3 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP06913.1 - 8.2e-08 31.0 2.7 1.3e-05 24.1 0.5 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 KFP06913.1 - 1e-06 28.2 0.1 2.8e-05 23.6 0.0 2.8 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_5 PF13202.1 KFP06913.1 - 0.00023 20.3 5.9 0.00026 20.1 0.1 3.6 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 KFP06913.1 - 0.0058 16.4 0.4 0.064 13.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KFP06913.1 - 0.007 15.9 0.5 0.035 13.7 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair Ribosomal_S7 PF00177.16 KFP06913.1 - 0.15 11.6 0.1 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e MPLKIP PF15502.1 KFP06914.1 - 1.2 9.8 9.8 1.4 9.6 6.8 1.1 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein LRR_8 PF13855.1 KFP06915.1 - 3.3e-24 84.3 11.6 1.2e-09 37.7 1.2 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KFP06915.1 - 3.5e-24 83.9 18.8 8.7e-08 31.6 2.9 5.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP06915.1 - 1.3e-18 64.1 18.1 0.024 14.6 0.2 8.9 8 0 0 8 8 8 6 Leucine Rich Repeat CH PF00307.26 KFP06915.1 - 4.6e-10 39.5 0.0 1.2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_7 PF13504.1 KFP06915.1 - 1.4e-09 36.5 13.6 2.8 8.5 0.2 8.3 8 0 0 8 8 8 2 Leucine rich repeat CAMSAP_CH PF11971.3 KFP06915.1 - 0.00072 19.1 0.0 0.0028 17.2 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain LRR_6 PF13516.1 KFP06915.1 - 0.0042 17.0 15.1 22 5.5 0.1 7.0 6 1 0 6 6 6 0 Leucine Rich repeat CDC24 PF06395.6 KFP06915.1 - 0.0048 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin IL6Ra-bind PF09240.5 KFP06916.1 - 7.4e-23 80.5 0.2 2.2e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 Interleukin-6 receptor alpha chain, binding fn3 PF00041.16 KFP06916.1 - 1e-09 38.4 0.2 0.0023 18.0 0.1 3.2 3 0 0 3 3 3 2 Fibronectin type III domain EpoR_lig-bind PF09067.5 KFP06916.1 - 0.0004 20.3 0.1 0.001 19.0 0.1 1.6 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding Tissue_fac PF01108.12 KFP06916.1 - 0.0033 17.1 1.4 1.5 8.5 0.0 3.3 2 1 1 3 3 3 2 Tissue factor 7tm_1 PF00001.16 KFP06917.1 - 9.4e-68 228.1 13.8 1.4e-67 227.6 9.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP06917.1 - 7.7e-13 48.1 14.3 2e-12 46.8 9.9 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP06917.1 - 0.0011 18.1 13.2 0.0011 18.1 9.1 2.4 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx RseC_MucC PF04246.7 KFP06917.1 - 0.046 13.2 0.2 0.046 13.2 0.2 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Pox_P21 PF05313.7 KFP06917.1 - 2.1 7.5 10.2 0.041 13.1 0.7 2.6 3 0 0 3 3 3 0 Poxvirus P21 membrane protein GDPD PF03009.12 KFP06918.1 - 1.4e-21 77.1 0.1 3.5e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family SPO22 PF08631.5 KFP06919.1 - 3.7e-56 190.2 16.6 7.3e-55 186.0 2.4 3.4 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.12 KFP06919.1 - 1.1e-07 31.1 7.8 0.0083 15.9 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP06919.1 - 1.4e-07 31.3 9.9 0.00016 21.5 0.5 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFP06919.1 - 8.6e-05 22.1 1.4 8.6e-05 22.1 0.9 4.4 6 0 0 6 6 6 1 TPR repeat TPR_1 PF00515.23 KFP06919.1 - 0.00052 19.5 10.6 0.042 13.4 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP06919.1 - 0.00054 20.2 3.2 0.025 14.9 0.0 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFP06919.1 - 0.0068 17.0 0.1 0.17 12.5 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP06919.1 - 0.011 15.4 0.0 0.011 15.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF493 PF04359.9 KFP06919.1 - 0.039 14.3 0.3 0.15 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF493) TPR_14 PF13428.1 KFP06919.1 - 0.26 12.0 3.7 4.7 8.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.17 KFP06920.1 - 2.6e-18 65.4 0.0 3.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06920.1 - 9.4e-14 51.0 0.0 1.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP06920.1 - 1.4e-13 50.5 0.0 1.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.1 KFP06921.1 - 1.9e-51 174.9 22.0 1.9e-51 174.9 15.3 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KFP06921.1 - 2.8e-35 121.5 26.9 2.8e-35 121.5 18.6 2.3 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 KFP06921.1 - 1.1e-23 82.7 6.9 1.1e-23 82.7 4.8 4.3 4 0 0 4 4 4 1 C-terminus of AA_permease PX PF00787.19 KFP06922.1 - 2.2e-21 75.7 0.2 2.4e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 PX domain PA26 PF04636.8 KFP06923.1 - 4.2e-168 559.7 0.2 4.7e-168 559.5 0.1 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) CMD PF02627.15 KFP06923.1 - 0.0036 17.1 0.0 0.0095 15.7 0.0 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family IL6Ra-bind PF09240.5 KFP06924.1 - 1.1e-18 67.2 0.0 2.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding EpoR_lig-bind PF09067.5 KFP06924.1 - 5.3e-08 32.7 0.1 1.2e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFP06924.1 - 1.7e-07 31.2 2.3 3.4e-07 30.2 0.5 2.2 2 0 0 2 2 2 1 Fibronectin type III domain COesterase PF00135.23 KFP06925.1 - 1.1e-187 624.9 0.0 1.3e-187 624.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFP06925.1 - 2.7e-05 23.8 0.1 8.1e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Connexin PF00029.14 KFP06926.1 - 7.9e-49 164.1 1.1 7.9e-49 164.1 0.8 2.4 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFP06926.1 - 1.5e-31 107.9 7.1 5.5e-31 106.1 5.0 2.0 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain DUF912 PF06024.7 KFP06926.1 - 1.5 8.9 3.8 35 4.5 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NOPS PF08075.6 KFP06927.1 - 1.8e-29 101.9 2.1 4.6e-29 100.5 1.4 1.8 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_1 PF00076.17 KFP06927.1 - 4e-29 100.0 0.0 2.8e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP06927.1 - 1.1e-19 70.0 0.0 1e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06927.1 - 3.1e-10 39.7 0.0 0.0011 18.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3256 PF11644.3 KFP06927.1 - 0.19 11.2 0.7 0.32 10.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Aldedh PF00171.17 KFP06927.1 - 1.5 7.0 4.9 2 6.6 3.4 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Totivirus_coat PF05518.6 KFP06927.1 - 6.3 4.4 8.4 8 4.1 5.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein CHORD PF04968.7 KFP06928.1 - 2.8e-53 178.0 27.2 1.5e-27 95.5 5.7 2.9 4 0 0 4 4 4 2 CHORD CS PF04969.11 KFP06928.1 - 1.2e-14 54.6 0.3 2.1e-14 53.8 0.2 1.4 1 0 0 1 1 1 1 CS domain zf-tcix PF14952.1 KFP06928.1 - 0.0067 15.7 1.9 1.4 8.2 0.1 2.8 2 0 0 2 2 2 2 Putative treble-clef, zinc-finger, Zn-binding DUF2733 PF10813.3 KFP06928.1 - 4.2 6.9 5.4 15 5.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Ras PF00071.17 KFP06929.1 - 3.1e-56 189.2 0.0 3.7e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06929.1 - 2.4e-17 63.5 0.0 3.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06929.1 - 6.5e-10 38.5 0.0 8.6e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP06929.1 - 0.0018 17.7 0.0 0.03 13.7 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP06929.1 - 0.019 14.0 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3799 PF12684.2 KFP06929.1 - 0.089 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) MMR_HSR1 PF01926.18 KFP06929.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3591 PF12157.3 KFP06930.1 - 1e-156 521.9 0.0 1.3e-155 518.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 KFP06930.1 - 5.3e-45 151.2 3.3 2e-22 78.8 0.5 3.0 2 0 0 2 2 2 2 Bromodomain TBP-binding PF09247.6 KFP06930.1 - 5.9e-24 84.0 3.1 2.4e-23 82.0 2.2 2.2 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.1 KFP06930.1 - 2.6e-15 55.7 0.3 7.9e-15 54.2 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle Glyco_transf_41 PF13844.1 KFP06931.1 - 1.5e-273 906.7 0.0 2e-273 906.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_1 PF00515.23 KFP06931.1 - 6.5e-98 316.7 27.4 2.2e-10 39.6 0.2 13.5 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_11 PF13414.1 KFP06931.1 - 4.6e-93 304.9 35.8 2.4e-16 59.1 0.4 8.8 7 2 2 9 9 9 8 TPR repeat TPR_17 PF13431.1 KFP06931.1 - 3.3e-75 242.1 27.5 5e-07 29.4 0.0 13.8 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_2 PF07719.12 KFP06931.1 - 1.1e-73 237.3 27.7 2.2e-08 33.3 0.3 13.2 13 0 0 13 13 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 KFP06931.1 - 4.4e-65 215.5 39.2 6.1e-14 51.7 0.2 7.9 1 1 9 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFP06931.1 - 8e-55 182.4 19.3 3.3e-10 40.3 0.2 8.4 5 2 3 8 8 8 8 Tetratricopeptide repeat TPR_14 PF13428.1 KFP06931.1 - 5.4e-54 175.7 16.6 1.3e-05 25.3 0.1 12.5 4 2 8 12 12 12 11 Tetratricopeptide repeat TPR_8 PF13181.1 KFP06931.1 - 1.3e-52 171.7 8.6 1.1e-05 24.8 0.1 12.3 12 0 0 12 12 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 KFP06931.1 - 1.5e-44 146.2 18.1 2.4e-05 23.8 0.0 13.1 13 1 1 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 KFP06931.1 - 2.7e-39 133.3 17.9 5.1e-06 26.7 0.4 9.5 3 3 6 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 KFP06931.1 - 5.8e-26 89.6 42.9 1.5e-05 24.7 0.2 12.3 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.1 KFP06931.1 - 1.8e-20 71.8 12.8 0.21 12.1 0.0 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFP06931.1 - 1.8e-15 56.5 15.9 0.015 15.1 0.0 6.7 4 2 3 7 7 7 5 Tetratricopeptide repeat NARP1 PF12569.3 KFP06931.1 - 1.6e-14 53.5 5.9 0.0014 17.5 0.0 5.8 1 1 4 6 6 6 3 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 KFP06931.1 - 4.2e-14 51.4 10.0 1.3 9.6 0.2 9.4 9 0 0 9 9 8 1 Tetratricopeptide repeat MIT PF04212.13 KFP06931.1 - 2.9e-09 36.6 21.5 0.024 14.5 0.0 8.9 7 2 3 10 10 8 3 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 KFP06931.1 - 6.9e-08 31.8 8.2 0.0003 19.9 0.4 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP06931.1 - 1.1e-07 31.8 23.3 0.00031 20.7 0.8 5.9 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 KFP06931.1 - 3.3e-06 26.7 1.2 1.5 8.7 0.0 5.8 5 1 1 6 6 5 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 KFP06931.1 - 2.5e-05 23.6 15.4 0.15 11.2 0.3 5.2 3 1 2 5 5 5 2 Est1 DNA/RNA binding domain FAT PF02259.18 KFP06931.1 - 0.00016 20.7 1.5 1.5 7.6 0.1 5.1 2 2 1 3 3 3 1 FAT domain TPR_21 PF09976.4 KFP06931.1 - 0.00031 20.6 12.8 0.42 10.5 0.0 5.4 5 2 0 5 5 4 2 Tetratricopeptide repeat TPR_5 PF12688.2 KFP06931.1 - 0.0053 16.7 5.1 1.7 8.7 0.1 4.2 3 2 2 5 5 4 2 Tetratrico peptide repeat RPN7 PF10602.4 KFP06931.1 - 0.0056 16.0 8.1 20 4.5 0.0 6.5 4 2 5 9 9 9 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.4 KFP06931.1 - 0.0066 15.6 3.3 26 4.1 0.0 5.4 7 0 0 7 7 7 0 SHNi-TPR DUF3366 PF11846.3 KFP06931.1 - 0.0081 16.0 17.2 0.045 13.6 0.2 4.7 4 1 1 6 6 4 2 Domain of unknown function (DUF3366) Tcf25 PF04910.9 KFP06931.1 - 0.013 14.4 0.5 0.04 12.8 0.1 2.0 2 0 0 2 2 2 0 Transcriptional repressor TCF25 DUF627 PF04781.7 KFP06931.1 - 0.022 14.3 0.8 6.2 6.4 0.0 4.4 3 1 2 5 5 5 0 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.1 KFP06931.1 - 0.07 13.0 0.6 0.99 9.3 0.0 3.3 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.7 KFP06931.1 - 0.077 12.5 0.3 29 4.2 0.0 3.6 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.1 KFP06931.1 - 0.27 11.3 14.1 1.9 8.6 0.2 6.2 4 2 1 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.12 KFP06931.1 - 0.35 11.1 13.4 3.9 7.7 0.6 5.3 3 2 2 6 6 6 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.1 KFP06931.1 - 1.5 9.0 5.5 3.9 7.7 0.2 3.8 4 2 0 4 4 4 0 Alkyl sulfatase dimerisation SprT-like PF10263.4 KFP06932.1 - 5.9e-15 55.2 0.0 2.4e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 SprT-like family TCL1_MTCP1 PF01840.12 KFP06933.1 - 1.6e-20 72.8 0.0 1.7e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 TCL1/MTCP1 family DUF1903 PF08991.5 KFP06934.1 - 1.7e-12 47.2 5.5 1.8e-12 47.2 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) FUN14 PF04930.10 KFP06935.1 - 1.6e-32 111.7 3.5 2e-32 111.4 2.4 1.1 1 0 0 1 1 1 1 FUN14 family SH3BGR PF04908.10 KFP06935.1 - 0.042 13.7 0.0 6.9 6.6 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Guanylate_kin PF00625.16 KFP06936.1 - 6.7e-58 195.1 0.1 1.2e-57 194.3 0.1 1.4 1 0 0 1 1 1 1 Guanylate kinase PDZ PF00595.19 KFP06936.1 - 3.5e-19 68.7 2.2 5.7e-19 68.0 0.8 1.9 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) SH3_2 PF07653.12 KFP06936.1 - 2.6e-10 39.6 0.0 7.6e-10 38.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP06936.1 - 4.4e-09 35.5 1.1 2.5e-08 33.1 0.8 2.2 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP06936.1 - 1.3e-07 31.1 0.0 3.1e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PDZ_2 PF13180.1 KFP06936.1 - 1.4e-05 24.8 0.2 0.00011 22.0 0.1 2.2 2 0 0 2 2 2 1 PDZ domain DUF258 PF03193.11 KFP06936.1 - 0.00087 18.5 0.0 0.0019 17.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Tricorn_PDZ PF14685.1 KFP06936.1 - 0.0021 17.7 0.4 0.27 11.0 0.1 3.2 3 1 0 3 3 3 1 Tricorn protease PDZ domain MMR_HSR1 PF01926.18 KFP06936.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RBFA PF02033.13 KFP06936.1 - 0.085 12.8 0.1 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 Ribosome-binding factor A IstB_IS21 PF01695.12 KFP06936.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DKCLD PF08068.7 KFP06937.1 - 1.7e-23 82.3 0.7 1.2e-22 79.5 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KFP06937.1 - 3e-23 82.6 0.2 3e-20 72.9 0.1 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KFP06937.1 - 7.3e-18 64.0 1.0 1.2e-17 63.3 0.7 1.4 1 0 0 1 1 1 1 PUA domain Methyltransf_31 PF13847.1 KFP06938.1 - 2.1e-13 50.1 0.0 3.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KFP06938.1 - 1.6e-12 46.7 0.1 4e-11 42.1 0.0 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.2 KFP06938.1 - 3.4e-08 34.0 0.0 6.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP06938.1 - 1.1e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP06938.1 - 1.9e-07 30.6 0.0 4.5e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KFP06938.1 - 8e-05 21.7 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KFP06938.1 - 0.00017 21.9 0.0 0.00046 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KFP06938.1 - 0.0023 17.5 0.1 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 KFP06938.1 - 0.0079 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 KFP06938.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KFP06938.1 - 0.022 13.9 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KFP06938.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DoxX_2 PF13564.1 KFP06939.1 - 9.2e-08 31.9 1.8 1.6e-07 31.1 1.3 1.4 1 1 0 1 1 1 1 DoxX-like family DUF4131 PF13567.1 KFP06939.1 - 0.012 14.9 1.2 0.083 12.2 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) HCV_NS2 PF01538.13 KFP06939.1 - 0.084 12.2 1.2 0.12 11.8 0.8 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DUF843 PF05814.6 KFP06939.1 - 0.1 12.4 2.6 0.12 12.2 0.5 1.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DoxX PF07681.7 KFP06939.1 - 0.35 11.3 5.6 0.041 14.2 0.8 1.8 2 1 0 2 2 2 0 DoxX DUF308 PF03729.8 KFP06939.1 - 0.39 10.7 0.0 0.39 10.7 0.0 3.2 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) NS3_envE PF02723.9 KFP06939.1 - 7.8 6.4 6.6 6.7 6.7 0.5 2.7 2 1 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E CENP-I PF07778.6 KFP06940.1 - 1.7e-226 752.3 14.9 2.3e-226 751.9 10.3 1.1 1 0 0 1 1 1 1 Mis6 TPR_11 PF13414.1 KFP06941.1 - 1.9e-08 33.8 5.2 6.4e-05 22.5 1.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFP06941.1 - 9.9e-06 25.0 5.1 0.023 14.5 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF1932 PF09130.6 KFP06941.1 - 0.23 11.2 1.7 13 5.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) TAFII55_N PF04658.8 KFP06942.1 - 1.1e-56 190.7 0.4 1.1e-56 190.7 0.3 2.2 2 1 0 2 2 2 1 TAFII55 protein conserved region Mo25 PF08569.6 KFP06942.1 - 0.23 10.4 9.8 0.45 9.5 6.8 1.4 1 0 0 1 1 1 0 Mo25-like Atg14 PF10186.4 KFP06942.1 - 1.4 7.7 18.3 2.4 7.0 12.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-Tim10_DDP PF02953.10 KFP06943.1 - 2.8e-12 45.7 0.1 3.4e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase_Tyr PF07714.12 KFP06944.1 - 1.3e-92 309.5 0.0 1.8e-92 309.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP06944.1 - 1.6e-47 161.8 0.0 2.2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP06944.1 - 3.6e-23 81.1 0.1 7.5e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFP06944.1 - 2.6e-12 45.9 0.0 5.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain BTK PF00779.14 KFP06944.1 - 5.1e-10 38.7 3.1 1.1e-09 37.6 2.2 1.6 1 0 0 1 1 1 1 BTK motif SH3_9 PF14604.1 KFP06944.1 - 3.2e-07 29.8 0.0 7.8e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 KFP06944.1 - 8e-05 21.7 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_2 PF07653.12 KFP06944.1 - 9.9e-05 21.7 0.0 0.00026 20.3 0.0 1.8 1 1 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFP06944.1 - 0.00013 22.0 0.0 0.00075 19.6 0.0 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain PH PF00169.24 KFP06944.1 - 0.0084 16.2 0.1 3.3 7.9 0.0 2.7 2 0 0 2 2 2 1 PH domain APH PF01636.18 KFP06944.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFP06944.1 - 0.06 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L44 PF00935.14 KFP06945.1 - 2e-32 111.0 10.0 2e-32 111.0 6.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 KFP06945.1 - 0.28 11.0 4.1 0.11 12.3 1.1 1.7 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Neur_chan_LBD PF02931.18 KFP06946.1 - 3.5e-55 186.4 0.1 4.9e-55 186.0 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP06946.1 - 1.1e-44 153.1 0.9 2e-38 132.6 0.1 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.17 KFP06947.1 - 2.4e-56 189.5 0.0 3.2e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP06947.1 - 6.5e-19 68.5 0.0 9.7e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP06947.1 - 7.1e-10 38.3 0.0 7.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP06947.1 - 2.2e-06 26.9 0.0 4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP06947.1 - 2.6e-06 27.3 0.0 4.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP06947.1 - 8.9e-06 25.2 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFP06947.1 - 0.0029 16.8 0.1 0.01 15.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFP06947.1 - 0.014 15.3 0.0 0.071 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 KFP06947.1 - 0.06 13.0 0.1 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 KFP06947.1 - 0.08 13.0 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KFP06947.1 - 0.08 12.2 0.0 0.16 11.2 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Thymosin PF01290.15 KFP06948.1 - 2.1e-20 72.0 9.6 2.3e-20 71.9 6.7 1.0 1 0 0 1 1 1 1 Thymosin beta-4 family DUF4522 PF15022.1 KFP06948.1 - 0.055 13.1 0.2 0.058 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) WH2 PF02205.15 KFP06948.1 - 0.076 12.6 0.7 0.098 12.2 0.5 1.2 1 0 0 1 1 1 0 WH2 motif Pribosyl_synth PF14572.1 KFP06949.1 - 2e-44 151.5 2.3 1.3e-37 129.3 1.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFP06949.1 - 3.4e-34 117.0 0.5 2.1e-33 114.4 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFP06949.1 - 2.3e-10 40.2 0.9 5.4e-10 39.0 0.5 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFP06949.1 - 0.00027 20.1 0.1 0.00043 19.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FERM_N PF09379.5 KFP06950.1 - 4.3e-07 29.8 0.1 5.4e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 FERM N-terminal domain PIH1 PF08190.7 KFP06951.1 - 3e-09 36.7 0.0 3e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Nsp1_C PF05064.8 KFP06952.1 - 5.1e-40 135.7 8.5 5.1e-40 135.7 5.9 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region AAA_32 PF13654.1 KFP06952.1 - 0.13 10.9 5.3 0.17 10.5 3.7 1.2 1 0 0 1 1 1 0 AAA domain Prp18 PF02840.10 KFP06952.1 - 0.41 10.4 7.9 4.2 7.1 1.9 2.3 1 1 1 2 2 2 0 Prp18 domain DUF4164 PF13747.1 KFP06952.1 - 0.76 9.9 10.0 0.062 13.4 1.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF342 PF03961.8 KFP06952.1 - 1.5 7.1 6.9 1.6 7.0 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Laminin_II PF06009.7 KFP06952.1 - 2.2 8.0 9.3 2.6 7.7 0.7 2.3 1 1 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 KFP06952.1 - 9.1 6.1 12.3 1.6 8.5 2.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 KFP06952.1 - 9.2 6.4 10.9 5 7.3 2.5 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RRM_6 PF14259.1 KFP06953.1 - 6.7e-09 35.6 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP06953.1 - 6.8e-09 35.2 0.0 1.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06953.1 - 0.0001 22.0 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KFP06953.1 - 0.025 14.1 0.0 0.6 9.6 0.0 2.3 2 0 0 2 2 2 0 Calcipressin PMP22_Claudin PF00822.15 KFP06954.1 - 4.3e-25 88.2 6.5 5.2e-25 88.0 4.5 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 KFP06954.1 - 4.2e-08 33.0 5.7 5.3e-08 32.7 3.6 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KFP06954.1 - 0.0063 16.1 5.6 0.0064 16.1 3.2 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF4064 PF13273.1 KFP06954.1 - 0.022 14.8 1.1 7.4 6.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Myf5 PF12232.3 KFP06954.1 - 0.12 13.0 0.7 0.3 11.7 0.5 1.8 1 0 0 1 1 1 0 Myogenic determination factor 5 ATP_synt_I PF03899.10 KFP06954.1 - 2.4 8.3 6.4 0.23 11.6 0.8 2.0 2 0 0 2 2 2 0 ATP synthase I chain DUF872 PF05915.7 KFP06954.1 - 4.9 7.0 5.8 0.42 10.4 0.2 2.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Ion_trans PF00520.26 KFP06955.1 - 1.2e-19 70.3 1.8 1.7e-19 69.8 1.3 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.24 KFP06955.1 - 1.6e-16 59.8 0.0 2.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.11 KFP06955.1 - 0.074 12.7 7.0 0.27 10.9 4.9 2.1 1 1 0 1 1 1 0 Ion channel Neur_chan_memb PF02932.11 KFP06956.1 - 2.5e-44 151.9 6.4 2.2e-39 135.7 0.8 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP06956.1 - 8.2e-39 132.9 1.6 1.1e-38 132.6 1.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_LBD PF02931.18 KFP06957.1 - 7.1e-50 169.1 0.0 1e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP06957.1 - 6.1e-47 160.5 6.2 6.4e-38 130.9 2.7 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_memb PF02932.11 KFP06958.1 - 3.6e-56 190.7 0.0 5.5e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.18 KFP06958.1 - 5.1e-39 133.6 0.1 7e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain SOXp PF12336.3 KFP06959.1 - 1.3e-31 109.0 2.9 1.3e-31 109.0 2.0 2.6 2 1 1 3 3 3 1 SOX transcription factor HMG_box PF00505.14 KFP06959.1 - 6.4e-27 93.6 3.0 9.6e-27 93.0 1.5 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFP06959.1 - 2.3e-11 43.9 2.0 3.7e-11 43.2 1.4 1.4 1 0 0 1 1 1 1 HMG-box domain MgtE_N PF03448.12 KFP06960.1 - 0.0037 17.5 27.4 12 6.3 19.0 2.3 1 1 0 1 1 1 1 MgtE intracellular N domain JHBP PF06585.6 KFP06960.1 - 0.029 13.1 13.0 9.9e+02 -1.7 9.0 3.8 1 1 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF445 PF04286.7 KFP06960.1 - 1 8.8 27.9 2.8 7.3 19.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF2939 PF11159.3 KFP06960.1 - 1.5 9.0 30.4 1.5e+04 -15.9 21.1 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Host_attach PF10116.4 KFP06960.1 - 3.4 7.8 27.4 1.5e+04 -12.8 19.0 4.5 1 1 0 1 1 1 0 Protein required for attachment to host cells DUF1104 PF06518.6 KFP06960.1 - 3.8 7.7 76.3 1.5e+04 -29.7 52.9 3.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) RHD3 PF05879.7 KFP06960.1 - 4.1 5.2 26.4 4.3 5.1 18.3 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) WASH-7_mid PF14744.1 KFP06960.1 - 4.8 5.9 22.0 3.7e+02 -0.3 15.3 2.0 1 1 0 1 1 1 0 WASH complex subunit 7 MgtE_N PF03448.12 KFP06961.1 - 5.4e-05 23.4 50.6 1.5e+04 -16.8 35.1 3.3 1 1 0 1 1 1 0 MgtE intracellular N domain DUF445 PF04286.7 KFP06961.1 - 0.78 9.2 52.1 3.8e+02 0.3 36.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) RHD3 PF05879.7 KFP06961.1 - 1.3 6.8 49.2 1.5 6.6 34.1 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) LRR_8 PF13855.1 KFP06963.1 - 1.9e-60 200.5 73.5 5.2e-17 61.3 0.9 6.6 2 2 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.2 KFP06963.1 - 2.8e-29 100.1 37.4 5e-10 38.7 0.2 7.8 3 2 8 11 11 11 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP06963.1 - 9.4e-17 60.9 0.4 3.8e-08 33.1 0.6 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP06963.1 - 1.4e-12 45.7 41.8 0.043 13.8 0.0 12.9 13 0 0 13 13 13 5 Leucine Rich Repeat LRRNT PF01462.13 KFP06963.1 - 0.00032 20.0 4.1 0.00032 20.0 2.8 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 KFP06963.1 - 0.0033 17.3 41.5 1.1 9.7 0.2 10.7 11 0 0 11 11 11 3 Leucine rich repeat LRR_8 PF13855.1 KFP06964.1 - 3.9e-53 177.0 57.0 6.3e-16 57.8 0.8 6.4 2 2 5 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 KFP06964.1 - 1.6e-19 69.1 44.5 1.8e-05 24.2 0.2 8.0 2 2 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP06964.1 - 1.1e-16 60.6 0.1 4.6e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP06964.1 - 4e-15 53.5 37.6 0.13 12.3 0.2 12.8 12 0 0 12 12 12 5 Leucine Rich Repeat LRRNT PF01462.13 KFP06964.1 - 0.00022 20.6 1.5 0.00022 20.6 1.0 2.9 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Sialidase PF02973.11 KFP06964.1 - 0.023 13.6 0.1 0.082 11.8 0.0 1.9 2 0 0 2 2 2 0 Sialidase, N-terminal domain IncA PF04156.9 KFP06964.1 - 0.099 12.2 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 IncA protein LRR_9 PF14580.1 KFP06964.1 - 0.59 9.6 9.2 8.5 5.9 0.5 3.6 2 2 1 3 3 3 0 Leucine-rich repeat Fe-ADH PF00465.14 KFP06966.1 - 1.3e-104 349.7 0.0 1.5e-104 349.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KFP06966.1 - 7.6e-15 54.8 0.0 3.8e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF4648 PF15505.1 KFP06967.1 - 1.3e-35 123.0 0.1 1.4e-35 123.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4648) Cmyb_C PF09316.5 KFP06968.1 - 6.9e-70 234.0 4.4 9e-70 233.6 1.7 2.3 2 0 0 2 2 2 1 C-myb, C-terminal Myb_DNA-binding PF00249.26 KFP06968.1 - 4e-51 170.8 16.1 2.5e-17 62.6 1.4 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFP06968.1 - 3.3e-42 142.3 20.1 4.6e-19 68.2 1.3 4.3 2 1 2 4 4 4 3 Myb-like DNA-binding domain LMSTEN PF07988.7 KFP06968.1 - 2.8e-26 90.5 0.3 5.7e-26 89.5 0.2 1.6 1 0 0 1 1 1 1 LMSTEN motif DegQ PF08181.6 KFP06968.1 - 0.027 14.2 2.1 0.083 12.6 0.6 2.3 2 0 0 2 2 2 0 DegQ (SacQ) family Sigma70_r4_2 PF08281.7 KFP06968.1 - 0.12 11.9 0.0 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 Spore_III_AB PF09548.5 KFP06968.1 - 0.12 12.1 0.4 3.7 7.2 0.0 3.0 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Rap1_C PF11626.3 KFP06968.1 - 0.22 11.4 9.9 27 4.7 4.2 3.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain OTU PF02338.14 KFP06969.1 - 1.7e-25 89.9 0.0 4.2e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Mut7-C PF01927.11 KFP06969.1 - 0.11 12.4 0.1 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 Mut7-C RNAse domain Pkinase PF00069.20 KFP06970.1 - 3.1e-66 223.1 0.0 3.6e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06970.1 - 1.5e-34 119.2 0.0 1.8e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP06970.1 - 2.8e-05 23.2 0.0 8.4e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 KFP06970.1 - 0.0006 20.2 0.1 0.001 19.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 KFP06970.1 - 0.0056 15.7 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP06970.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MCM PF00493.18 KFP06971.1 - 1.9e-16 59.7 0.0 1.1e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 MCM2/3/5 family LRR_4 PF12799.2 KFP06972.1 - 2.1e-19 68.6 26.5 7.2e-07 28.6 2.6 5.2 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP06972.1 - 7.7e-13 48.0 19.6 4.8e-05 23.0 1.9 4.3 2 2 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 KFP06972.1 - 4.2e-11 42.7 10.1 1.3e-05 24.8 0.7 2.5 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 KFP06972.1 - 4.2e-10 38.2 20.4 0.18 11.9 0.1 7.1 6 2 1 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 KFP06972.1 - 1.7e-08 33.6 22.8 0.09 12.9 0.0 6.6 4 2 2 6 6 6 5 Leucine Rich repeat LRR_7 PF13504.1 KFP06972.1 - 7.5e-05 22.3 14.3 0.89 10.0 0.0 6.4 7 0 0 7 7 7 3 Leucine rich repeat DUF1268 PF06896.6 KFP06972.1 - 3 8.2 5.9 11 6.4 1.4 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1268) FNIP PF05725.7 KFP06972.1 - 4.2 7.4 8.5 16 5.5 3.2 3.5 2 1 0 2 2 2 0 FNIP Repeat JAB PF01398.16 KFP06973.1 - 2.5e-32 110.9 0.0 3.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KFP06973.1 - 1.3e-06 27.8 0.0 2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 KFP06973.1 - 0.0037 16.7 0.0 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Sec7 PF01369.15 KFP06974.1 - 1.7e-72 243.1 0.6 6.9e-72 241.1 0.4 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KFP06974.1 - 7.6e-56 188.1 4.6 7.6e-56 188.1 3.2 3.4 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFP06974.1 - 1.1e-31 108.1 0.1 1.1e-31 108.1 0.1 5.2 8 0 0 8 8 8 1 Domain of unknown function (DUF1981) Peptidase_M14 PF00246.19 KFP06975.1 - 3.4e-85 286.0 0.1 4.6e-85 285.5 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KFP06975.1 - 3.2e-15 55.5 0.1 3.2e-15 55.5 0.1 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Pkinase PF00069.20 KFP06976.1 - 1.7e-38 132.2 0.0 2.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06976.1 - 4.8e-31 107.7 0.0 7.6e-31 107.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFP06976.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 1 0 1 1 1 0 RIO1 family Acetyltransf_13 PF13880.1 KFP06977.1 - 3.4e-30 103.6 0.0 7.2e-30 102.5 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KFP06977.1 - 6.6e-18 63.9 0.8 1.3e-17 63.0 0.5 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF814 PF05670.8 KFP06978.1 - 3.5e-08 33.1 0.0 5.6e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF814) Syntaxin PF00804.20 KFP06979.1 - 6.3e-06 26.2 6.2 0.12 12.5 1.1 3.9 1 1 2 4 4 4 2 Syntaxin WEMBL PF05701.6 KFP06979.1 - 4.9e-05 21.9 1.3 4.9e-05 21.9 0.9 1.9 1 1 1 2 2 2 1 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 KFP06979.1 - 0.00013 19.8 4.4 0.00017 19.4 3.1 1.1 1 0 0 1 1 1 1 Myosin tail DUF1664 PF07889.7 KFP06979.1 - 0.0021 17.8 5.5 1.2 8.9 1.0 3.6 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) AAA_13 PF13166.1 KFP06979.1 - 0.0023 16.5 2.7 0.0071 14.8 0.1 2.0 1 1 1 2 2 2 1 AAA domain HAUS-augmin3 PF14932.1 KFP06979.1 - 0.0042 16.3 2.1 0.0042 16.3 1.5 2.3 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 DUF2703 PF10865.3 KFP06979.1 - 0.0069 16.3 1.8 0.046 13.6 0.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2703) NPV_P10 PF05531.7 KFP06979.1 - 0.0085 16.3 5.2 2 8.7 1.4 4.4 3 1 1 4 4 4 1 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KFP06979.1 - 0.0099 15.0 10.8 0.35 9.9 1.5 3.0 1 1 2 3 3 3 2 Reovirus sigma C capsid protein DUF948 PF06103.6 KFP06979.1 - 0.02 14.7 6.2 0.82 9.5 0.4 4.0 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF904 PF06005.7 KFP06979.1 - 0.035 14.3 2.6 2.5 8.4 2.0 2.9 3 1 0 3 3 2 0 Protein of unknown function (DUF904) Syntaxin-6_N PF09177.6 KFP06979.1 - 0.091 13.1 8.9 2.7 8.4 0.8 3.8 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 KFP06979.1 - 0.095 12.5 6.6 2.5 7.9 1.7 2.5 2 0 0 2 2 2 0 Tropomyosin like MCPsignal PF00015.16 KFP06979.1 - 0.17 11.3 4.6 3.6 7.0 0.4 3.0 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TPR_MLP1_2 PF07926.7 KFP06979.1 - 0.18 11.5 10.4 0.025 14.3 2.0 2.6 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Transcrip_act PF04949.8 KFP06979.1 - 0.2 11.2 2.6 0.78 9.3 0.4 2.4 3 0 0 3 3 3 0 Transcriptional activator ADIP PF11559.3 KFP06979.1 - 0.43 10.4 6.5 1.2 9.0 0.0 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding BCAS2 PF05700.6 KFP06979.1 - 0.44 9.9 7.7 2.9 7.2 0.2 3.1 2 1 1 3 3 3 0 Breast carcinoma amplified sequence 2 (BCAS2) Cep57_CLD_2 PF14197.1 KFP06979.1 - 0.48 10.3 9.7 3 7.8 0.4 3.2 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Kazal_1 PF00050.16 KFP06979.1 - 0.49 10.4 3.3 3.1 7.8 0.2 2.4 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Lebercilin PF15619.1 KFP06979.1 - 0.66 9.3 10.6 1.6 8.1 2.1 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.17 KFP06979.1 - 1.3 9.0 5.3 5 7.1 0.4 3.5 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 KFP06979.1 - 3.1 7.3 19.6 0.44 10.1 6.9 2.5 1 1 1 2 2 2 0 IncA protein FlaC_arch PF05377.6 KFP06979.1 - 7.7 6.4 10.3 25 4.8 0.2 4.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Clusterin PF01093.12 KFP06980.1 - 7.2e-129 430.4 5.7 8.6e-111 370.8 2.1 2.0 2 0 0 2 2 2 2 Clusterin U1snRNP70_N PF12220.3 KFP06980.1 - 1.5 9.1 6.9 0.63 10.4 1.3 2.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EamA PF00892.15 KFP06981.1 - 4.1e-09 36.5 15.3 5.1e-07 29.7 0.3 3.0 2 1 0 2 2 2 2 EamA-like transporter family DUF914 PF06027.7 KFP06981.1 - 4.1e-08 32.4 3.6 2.4e-07 29.9 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 KFP06981.1 - 1.7e-07 31.0 7.5 0.00013 21.6 1.5 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KFP06981.1 - 1.1e-05 24.6 0.1 2.1e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KFP06981.1 - 0.0092 14.9 4.9 0.027 13.3 0.4 2.1 1 1 1 2 2 2 1 UAA transporter family EmrE PF13536.1 KFP06981.1 - 3.5 7.8 17.2 0.091 12.9 1.5 3.1 2 2 1 3 3 3 0 Multidrug resistance efflux transporter Ion_trans_2 PF07885.11 KFP06982.1 - 5.6e-38 128.5 15.6 7e-20 70.5 0.1 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 KFP06982.1 - 1.7e-05 24.1 12.5 0.0027 16.9 0.2 3.0 1 1 1 2 2 2 2 Ion transport protein IRK PF01007.15 KFP06982.1 - 0.061 12.1 1.1 0.35 9.6 0.0 2.2 2 0 0 2 2 2 0 Inward rectifier potassium channel hGDE_N PF14699.1 KFP06982.1 - 0.27 11.1 1.3 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain from the human glycogen debranching enzyme DUF2254 PF10011.4 KFP06982.1 - 8.3 4.7 6.4 8.2 4.7 0.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2254) 7tm_1 PF00001.16 KFP06984.1 - 5.5e-10 38.8 0.5 5.5e-10 38.8 0.3 1.3 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Kelch_1 PF01344.20 KFP06985.1 - 6.6e-70 230.4 9.2 1.2e-14 53.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFP06985.1 - 5.3e-46 152.9 4.4 3.3e-09 36.5 0.0 6.3 4 1 2 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFP06985.1 - 2.6e-30 103.8 9.1 1.1e-06 28.6 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP06985.1 - 2.7e-28 96.6 9.6 3.5e-05 23.3 0.0 6.3 6 0 0 6 6 6 5 Kelch motif BACK PF07707.10 KFP06985.1 - 2.2e-27 94.8 0.7 2.2e-27 94.8 0.5 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFP06985.1 - 9.8e-27 92.4 6.6 7.5e-06 25.6 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFP06985.1 - 2.5e-25 88.6 2.8 3.5e-25 88.1 1.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.1 KFP06985.1 - 6.4e-08 32.3 9.2 0.54 10.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif AF-4 PF05110.8 KFP06986.1 - 0 1200.1 83.9 0 1199.9 58.1 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Y_phosphatase PF00102.22 KFP06987.1 - 3.8e-77 258.7 0.0 4.3e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP06987.1 - 4.5e-05 23.0 0.0 8.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFP06987.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate RVT_1 PF00078.22 KFP06988.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lipase_GDSL_2 PF13472.1 KFP06989.1 - 7.3e-05 22.9 0.0 0.00018 21.7 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.20 KFP06990.1 - 7.5e-67 225.2 0.0 9.5e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP06990.1 - 7.2e-31 107.1 0.0 1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFP06990.1 - 4.3e-07 29.2 0.1 6.6e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP06990.1 - 0.00018 20.5 0.1 0.00033 19.6 0.1 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFP06990.1 - 0.00024 20.5 0.3 0.00044 19.6 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFP06990.1 - 0.00047 19.9 0.0 0.00075 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RhoGAP PF00620.22 KFP06992.1 - 9.1e-49 164.9 0.0 2.6e-48 163.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KFP06992.1 - 1.7e-14 53.8 0.2 1.7e-14 53.8 0.1 2.9 2 2 0 2 2 2 1 PH domain PH_11 PF15413.1 KFP06992.1 - 3.8e-07 30.3 0.3 3.8e-07 30.3 0.2 3.4 4 1 0 4 4 4 1 Pleckstrin homology domain Tropomyosin_1 PF12718.2 KFP06992.1 - 0.01 15.7 11.7 0.01 15.7 8.1 2.2 2 0 0 2 2 2 0 Tropomyosin like PH_9 PF15410.1 KFP06992.1 - 0.012 15.7 0.4 0.42 10.7 0.3 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain ADIP PF11559.3 KFP06992.1 - 2 8.2 15.7 0.028 14.3 4.4 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KFP06992.1 - 2.6 7.5 14.3 4 6.9 8.1 2.4 2 1 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 KFP06992.1 - 6.9 6.7 15.5 8.6 6.4 3.7 3.7 2 1 1 3 3 3 0 bZIP transcription factor PCI PF01399.22 KFP06993.1 - 5.8e-18 65.1 3.6 1e-17 64.3 0.0 2.8 3 1 0 3 3 3 1 PCI domain TPR_12 PF13424.1 KFP06993.1 - 0.0029 17.4 4.3 0.22 11.5 1.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP06993.1 - 0.011 15.5 1.5 1.3 8.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.4 KFP06993.1 - 0.017 14.5 0.8 0.031 13.6 0.6 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_14 PF13428.1 KFP06993.1 - 0.15 12.7 0.1 0.15 12.7 0.1 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF972 PF06156.8 KFP06993.1 - 1.2 9.5 7.6 3.5 8.0 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF972) TPR_19 PF14559.1 KFP06993.1 - 2.5 8.5 8.6 0.38 11.1 1.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TCR PF03638.10 KFP06994.1 - 3.8e-24 84.2 55.7 6.6e-13 48.2 15.3 2.7 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain WD40 PF00400.27 KFP06995.1 - 2.8e-14 52.3 7.8 0.0097 15.7 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Sec16_C PF12931.2 KFP06995.1 - 6.8e-07 29.3 1.6 1.7e-06 28.0 1.1 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.6 KFP06995.1 - 0.00054 19.7 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 KFP06995.1 - 0.014 15.2 0.1 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Prp18 domain FA_desaturase PF00487.19 KFP06996.1 - 1.8e-18 66.9 11.1 2.5e-18 66.4 7.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase UbiA PF01040.13 KFP06996.1 - 0.0094 15.1 1.6 1.1 8.4 0.2 2.2 2 0 0 2 2 2 2 UbiA prenyltransferase family PetL PF05115.9 KFP06996.1 - 0.84 9.5 4.5 0.36 10.7 0.8 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Frag1 PF10277.4 KFP06997.1 - 6.9e-44 149.8 8.3 8.1e-44 149.6 5.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 KFP06997.1 - 3.9e-05 23.0 6.3 3.9e-05 23.0 4.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF998) DUF1129 PF06570.6 KFP06997.1 - 0.025 13.9 0.8 0.025 13.9 0.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) HAD_2 PF13419.1 KFP06998.1 - 1.3e-19 71.0 0.0 1.8e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 KFP06999.1 - 5.6e-40 134.8 0.1 9.2e-19 66.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP06999.1 - 7.1e-31 105.9 0.0 2.3e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP06999.1 - 9.7e-12 44.5 0.0 9.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP06999.1 - 1.5e-05 24.7 0.3 0.013 15.3 0.1 2.8 2 2 1 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFP06999.1 - 0.00024 20.8 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 KFP06999.1 - 0.013 15.4 0.8 1.4 9.0 0.0 3.1 4 0 0 4 4 4 0 Nmi/IFP 35 domain (NID) RRM_1 PF00076.17 KFP07000.1 - 5.4e-42 141.2 0.8 9.9e-21 73.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07000.1 - 1e-32 111.8 0.1 3.4e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07000.1 - 2.2e-12 46.6 0.4 7.5e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP07000.1 - 3.5e-07 30.0 0.8 0.018 14.8 0.0 2.7 2 1 0 2 2 2 2 RNA binding motif NID PF07292.8 KFP07000.1 - 0.00011 22.1 1.4 0.024 14.6 0.0 2.5 2 1 0 2 2 2 2 Nmi/IFP 35 domain (NID) Nup35_RRM_2 PF14605.1 KFP07000.1 - 0.0015 18.2 0.0 0.059 13.1 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif HORMA PF02301.13 KFP07001.1 - 2.1e-44 151.5 0.3 2.4e-44 151.3 0.2 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 KFP07001.1 - 0.038 13.4 0.2 0.051 13.0 0.1 1.4 1 1 0 1 1 1 0 Autophagy-related protein 13 PAC2 PF09754.4 KFP07001.1 - 0.097 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 PAC2 family Ribosomal_L30_N PF08079.7 KFP07002.1 - 5.8e-15 55.0 8.5 5.8e-15 55.0 5.9 1.8 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KFP07002.1 - 2.1e-13 49.5 1.6 2.1e-13 49.5 1.1 2.4 2 1 1 3 3 3 1 Ribosomal protein L30p/L7e PDEase_I PF00233.14 KFP07003.1 - 3.8e-70 236.3 1.2 3.8e-70 236.3 0.8 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFP07003.1 - 2e-42 144.9 0.0 2.6e-22 79.5 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFP07003.1 - 7.4e-15 55.1 0.0 4.2e-06 26.8 0.0 2.9 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 KFP07003.1 - 5.7e-14 52.8 0.0 9.5e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 GAF domain UCH PF00443.24 KFP07004.1 - 1.5e-19 70.1 0.5 3.5e-19 68.9 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Calsarcin PF05556.6 KFP07005.1 - 6e-85 284.7 0.4 7.3e-85 284.4 0.3 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) Calsarcin PF05556.6 KFP07006.1 - 3.7e-05 23.1 12.7 0.8 8.8 0.0 3.9 3 1 0 3 3 3 3 Calcineurin-binding protein (Calsarcin) PDZ_2 PF13180.1 KFP07006.1 - 0.00089 19.1 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KFP07006.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Sec23_trunk PF04811.10 KFP07007.1 - 2.4e-82 275.9 0.1 4e-82 275.2 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFP07007.1 - 5.3e-23 80.4 0.1 1e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFP07007.1 - 1.5e-17 63.9 1.6 2.3e-17 63.2 0.0 2.2 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFP07007.1 - 2.7e-14 52.4 9.0 5.9e-14 51.3 6.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFP07007.1 - 2.2e-08 33.6 0.0 5.8e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat MT-A70 PF05063.9 KFP07008.1 - 4.8e-63 211.8 0.0 6.6e-63 211.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 SRCR PF00530.13 KFP07009.1 - 1.2e-117 384.8 31.3 5.1e-33 113.3 3.3 4.1 4 0 0 4 4 4 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.1 KFP07009.1 - 2.7e-23 82.0 16.6 2.6e-06 27.5 1.2 4.8 4 1 0 4 4 4 4 Scavenger receptor cysteine-rich domain SapB_2 PF03489.12 KFP07009.1 - 0.035 14.1 0.2 1.1e+02 2.9 0.0 4.1 4 0 0 4 4 4 0 Saposin-like type B, region 2 HMG_CoA_synt_N PF01154.12 KFP07009.1 - 0.13 11.8 0.7 2.9 7.4 0.0 2.6 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal HSNSD PF12062.3 KFP07010.1 - 3.3e-258 856.9 0.7 4.8e-258 856.3 0.5 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 KFP07010.1 - 4.7e-43 147.3 0.0 7.8e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP07010.1 - 0.002 19.0 0.9 0.0044 17.9 0.1 2.0 2 0 0 2 2 2 1 Sulfotransferase family RVT_1 PF00078.22 KFP07012.1 - 0.084 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phe_tRNA-synt_N PF02912.13 KFP07013.1 - 0.089 12.5 0.2 1.1 8.9 0.0 2.6 2 1 1 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain HSNSD PF12062.3 KFP07014.1 - 1.1e-256 851.9 0.0 1.8e-256 851.1 0.0 1.4 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 KFP07014.1 - 9.8e-42 143.0 0.0 1.6e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP07014.1 - 0.0015 19.5 0.1 0.0069 17.3 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family UDPGT PF00201.13 KFP07015.1 - 3.8e-120 401.8 0.0 4.5e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFP07015.1 - 9.4e-06 25.3 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Imm20 PF15568.1 KFP07015.1 - 0.0027 17.5 0.1 0.0052 16.6 0.1 1.4 1 0 0 1 1 1 1 Immunity protein 20 Sulfatase PF00884.18 KFP07018.1 - 2.4e-45 155.0 0.1 3.6e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KFP07018.1 - 2.4e-05 24.6 0.0 7.1e-05 23.0 0.0 1.8 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase PKD PF00801.15 KFP07019.1 - 1.8e-08 33.9 0.0 1.6e-07 30.9 0.0 2.4 2 1 0 2 2 2 1 PKD domain BNR PF02012.15 KFP07019.1 - 3.3e-06 26.0 5.8 1.4 9.0 0.2 5.2 4 0 0 4 4 4 3 BNR/Asp-box repeat PH PF00169.24 KFP07020.1 - 1.2e-26 92.9 4.0 6.4e-14 52.0 1.0 2.9 3 0 0 3 3 3 2 PH domain ERM PF00769.14 KFP07020.1 - 2.1e-05 24.1 9.2 2.1e-05 24.1 6.4 1.8 2 0 0 2 2 2 1 Ezrin/radixin/moesin family PH_9 PF15410.1 KFP07020.1 - 4.2e-05 23.6 0.8 1.4 9.1 0.3 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 KFP07020.1 - 0.0029 17.8 5.7 0.35 11.1 0.2 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain GAS PF13851.1 KFP07020.1 - 0.2 10.8 17.7 0.53 9.4 12.3 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KFP07020.1 - 0.48 9.4 13.0 1.2 8.0 9.0 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 KFP07020.1 - 0.92 9.3 17.6 0.63 9.8 3.1 3.1 3 0 0 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.14 KFP07020.1 - 3 5.5 4.7 5.6 4.6 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LIM PF00412.17 KFP07021.1 - 8.2e-40 134.6 43.7 7.9e-14 51.4 2.1 4.3 4 0 0 4 4 4 4 LIM domain VHP PF02209.14 KFP07021.1 - 5.6e-17 61.1 2.3 9.3e-17 60.4 1.6 1.4 1 0 0 1 1 1 1 Villin headpiece domain TPR_12 PF13424.1 KFP07022.1 - 5.8e-20 71.0 42.9 2.5e-06 27.3 0.9 8.8 7 2 1 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFP07022.1 - 4e-07 29.5 44.7 0.0043 16.6 2.5 8.4 5 2 5 10 10 10 4 TPR repeat TPR_1 PF00515.23 KFP07022.1 - 1.2e-05 24.6 39.1 0.028 14.0 0.1 11.1 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP07022.1 - 1.5e-05 24.5 41.6 0.31 11.0 0.3 11.0 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFP07022.1 - 9.4e-05 22.2 12.5 4 7.5 0.3 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFP07022.1 - 0.00019 21.7 11.4 11 6.9 0.1 7.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFP07022.1 - 0.00038 21.0 22.7 0.088 13.5 0.1 7.8 7 1 1 8 8 8 1 Tetratricopeptide repeat SH3_1 PF00018.23 KFP07022.1 - 0.00073 18.8 0.1 0.0071 15.7 0.0 2.4 2 0 0 2 2 2 1 SH3 domain TPR_21 PF09976.4 KFP07022.1 - 0.0089 15.9 1.3 0.037 13.9 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP07022.1 - 0.0091 15.7 42.2 0.028 14.2 0.2 10.5 11 2 3 14 14 13 2 Tetratricopeptide repeat SH3_2 PF07653.12 KFP07022.1 - 0.025 14.0 0.0 0.069 12.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain TPR_19 PF14559.1 KFP07022.1 - 0.4 11.0 18.9 0.053 13.8 0.5 5.8 5 2 3 8 8 7 0 Tetratricopeptide repeat DUF1877 PF08974.5 KFP07022.1 - 0.41 10.2 4.4 0.26 10.9 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) TPR_7 PF13176.1 KFP07022.1 - 0.95 9.4 26.3 0.26 11.1 0.1 8.2 10 0 0 10 10 8 0 Tetratricopeptide repeat Trypsin_2 PF13365.1 KFP07023.1 - 3.1e-19 69.1 0.2 4.4e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KFP07023.1 - 2.4e-15 56.6 0.0 3.3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.4 KFP07023.1 - 1.7e-05 23.5 2.0 0.03 12.7 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.8 KFP07023.1 - 0.00054 19.0 0.1 0.25 10.2 0.0 2.1 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.11 KFP07023.1 - 0.016 14.5 0.2 4.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF31) HAS-barrel PF09378.5 KFP07023.1 - 0.072 12.9 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 HAS barrel domain AdoMet_MTase PF07757.8 KFP07024.1 - 2.4e-41 140.3 0.1 4.6e-41 139.4 0.1 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KFP07024.1 - 0.0058 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP07024.1 - 0.0061 16.1 0.0 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KFP07024.1 - 0.014 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KFP07024.1 - 0.031 13.9 0.1 0.096 12.3 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFP07024.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF1247 PF06851.6 KFP07024.1 - 0.12 11.9 1.4 0.16 11.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) 7tm_1 PF00001.16 KFP07025.1 - 1.4e-38 132.5 19.1 1.8e-38 132.1 13.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PGG PF13962.1 KFP07025.1 - 0.027 14.0 1.0 0.027 14.0 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function gpUL132 PF11359.3 KFP07025.1 - 1.8 7.8 6.8 0.5 9.6 1.7 2.0 2 0 0 2 2 2 0 Glycoprotein UL132 Git3 PF11710.3 KFP07025.1 - 1.9 7.9 15.0 1.9 7.9 9.1 1.9 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Peptidase_M14 PF00246.19 KFP07026.1 - 7.2e-77 258.7 0.0 9.4e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Fz PF01392.17 KFP07026.1 - 4.6e-19 68.8 3.7 1.2e-18 67.5 2.5 1.7 1 0 0 1 1 1 1 Fz domain CarboxypepD_reg PF13620.1 KFP07026.1 - 2.7e-15 56.1 0.0 5.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFP07026.1 - 1.6e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Glypican PF01153.14 KFP07026.1 - 0.027 13.0 2.3 0.042 12.4 1.6 1.1 1 0 0 1 1 1 0 Glypican AstE_AspA PF04952.9 KFP07026.1 - 0.037 12.9 0.0 1.8 7.3 0.1 2.5 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family RVT_1 PF00078.22 KFP07027.1 - 6e-14 51.9 0.0 9.9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFP07027.1 - 3.2e-07 29.8 0.1 5.5e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Homeobox PF00046.24 KFP07028.1 - 1.4e-19 69.4 1.3 2e-19 68.9 0.9 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP07028.1 - 0.09 12.4 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.3 KFP07028.1 - 0.1 11.6 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez 7tm_1 PF00001.16 KFP07029.1 - 1.5e-79 266.8 4.3 2.2e-79 266.2 3.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP07029.1 - 3.8e-09 36.0 17.7 3.4e-06 26.4 5.2 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP07029.1 - 8.3e-07 28.4 12.5 0.00027 20.1 1.7 2.3 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srv 7TM_GPCR_Srx PF10328.4 KFP07029.1 - 4.8e-06 25.8 15.7 1.9e-05 23.9 4.5 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srx Alpha-2-MRAP_C PF06401.6 KFP07030.1 - 2.7e-101 337.8 29.7 2.7e-101 337.8 20.6 1.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N PF06400.6 KFP07030.1 - 6.4e-29 100.0 23.6 2.7e-28 98.0 3.3 3.5 3 1 0 3 3 3 3 Alpha-2-macroglobulin RAP, N-terminal domain Med30 PF11315.3 KFP07030.1 - 0.0081 16.3 3.6 0.0081 16.3 2.5 2.0 1 1 1 2 2 2 1 Mediator complex subunit 30 IL7 PF01415.11 KFP07030.1 - 0.025 14.2 0.5 0.059 13.0 0.3 1.6 1 0 0 1 1 1 0 Interleukin 7/9 family PriCT_2 PF08707.6 KFP07030.1 - 0.046 13.6 0.8 0.51 10.2 0.1 2.3 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) DUF2278 PF10042.4 KFP07030.1 - 0.14 11.8 3.1 0.2 11.3 1.8 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) DNA_ligase_A_C PF04679.10 KFP07030.1 - 3.3 8.1 5.5 12 6.3 0.1 3.0 2 1 0 3 3 3 0 ATP dependent DNA ligase C terminal region Spectrin PF00435.16 KFP07030.1 - 6.9 7.0 20.8 2.2 8.6 4.0 2.9 3 1 0 3 3 3 0 Spectrin repeat IRS PF02174.12 KFP07031.1 - 4.1e-09 35.9 0.0 9.6e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Trypsin PF00089.21 KFP07032.1 - 1.9e-74 249.9 0.4 2.8e-74 249.4 0.3 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFP07032.1 - 3.3e-25 87.9 1.3 3.3e-25 87.9 0.9 2.7 3 0 0 3 3 3 1 Kringle domain fn2 PF00040.14 KFP07032.1 - 2.1e-13 50.0 6.9 2.1e-13 50.0 4.8 3.3 2 0 0 2 2 2 1 Fibronectin type II domain EGF PF00008.22 KFP07032.1 - 1.9e-10 40.5 32.8 3.4e-06 26.8 7.8 3.9 3 0 0 3 3 3 2 EGF-like domain fn1 PF00039.13 KFP07032.1 - 3.4e-05 23.5 1.7 3.4e-05 23.5 1.1 3.0 3 0 0 3 3 3 1 Fibronectin type I domain EGF_2 PF07974.8 KFP07032.1 - 5.5e-05 23.2 33.4 0.0041 17.2 9.2 4.2 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.2 KFP07032.1 - 0.0059 16.5 5.2 0.0059 16.5 3.6 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF cEGF PF12662.2 KFP07032.1 - 1.4 8.6 11.3 0.18 11.4 3.3 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like RBD PF02196.10 KFP07033.1 - 1.1e-35 121.1 0.3 2.1e-19 69.0 0.0 2.9 3 0 0 3 3 3 2 Raf-like Ras-binding domain RGS PF00615.14 KFP07033.1 - 2.5e-28 98.5 3.3 4.4e-28 97.7 2.3 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PDZ PF00595.19 KFP07033.1 - 8.5e-14 51.4 0.1 1.1e-12 47.9 0.0 2.9 3 1 1 4 4 4 1 PDZ domain (Also known as DHR or GLGF) GoLoco PF02188.12 KFP07033.1 - 1.8e-09 36.6 0.2 1.8e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 GoLoco motif PID PF00640.18 KFP07033.1 - 5.5e-05 23.1 0.1 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) TUG-UBL1 PF11470.3 KFP07033.1 - 0.00079 19.3 0.0 0.092 12.6 0.0 3.2 3 0 0 3 3 3 1 GLUT4 regulating protein TUG PDZ_2 PF13180.1 KFP07033.1 - 0.00081 19.2 0.0 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Myb_DNA-bind_4 PF13837.1 KFP07034.1 - 1.4e-11 44.3 1.3 1.4e-11 44.3 0.9 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain PBC PF03792.8 KFP07034.1 - 0.016 14.9 7.7 0.3 10.7 2.5 2.3 2 1 0 2 2 2 0 PBC domain GPI PF06560.6 KFP07034.1 - 0.09 11.7 0.1 0.2 10.6 0.1 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) MADF_DNA_bdg PF10545.4 KFP07034.1 - 0.14 12.3 0.2 0.14 12.3 0.1 2.6 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TipAS PF07739.8 KFP07034.1 - 2.8 8.2 7.1 0.56 10.5 0.3 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF3652 PF12372.3 KFP07035.1 - 1.9e-16 59.3 0.1 2.3e-15 55.9 0.0 2.6 2 0 0 2 2 2 1 Huntingtin protein region HEAT PF02985.17 KFP07035.1 - 2.3e-10 39.6 5.3 0.098 12.7 0.0 8.1 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KFP07035.1 - 7.1e-09 35.8 0.8 0.22 11.8 0.0 5.4 3 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KFP07035.1 - 0.00012 22.4 8.0 1.1 9.8 0.1 7.6 6 0 0 6 6 6 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFP07035.1 - 0.0053 17.1 0.7 2 8.8 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region PRANC PF09372.5 KFP07035.1 - 0.067 13.1 0.7 5.2 7.1 0.1 3.3 3 0 0 3 3 3 0 PRANC domain Pkinase PF00069.20 KFP07036.1 - 1.3e-60 204.7 0.0 1.8e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07036.1 - 1.1e-34 119.7 0.0 1.5e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFP07036.1 - 4.9e-22 78.2 0.2 1.2e-21 76.9 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kinase-like PF14531.1 KFP07036.1 - 0.00014 20.9 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UDPG_MGDP_dh_C PF03720.10 KFP07036.1 - 0.14 12.2 0.1 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Nop14 PF04147.7 KFP07037.1 - 5.7e-256 851.6 38.0 6.4e-256 851.4 26.4 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2810 PF10928.3 KFP07037.1 - 0.025 14.2 0.7 3 7.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2810) PAP_central PF04928.12 KFP07037.1 - 1.1 7.9 6.3 1.3 7.7 3.1 2.0 2 0 0 2 2 2 0 Poly(A) polymerase central domain MFS_1 PF07690.11 KFP07038.1 - 1.7e-35 122.3 45.9 4.6e-30 104.5 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP07038.1 - 5.5e-12 44.9 7.5 5.5e-12 44.9 5.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFP07038.1 - 1.2e-06 26.9 3.0 1.2e-06 26.9 2.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Abhydro_lipase PF04083.11 KFP07038.1 - 0.041 13.2 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Aldolase_II PF00596.16 KFP07039.1 - 5.1e-44 150.0 0.1 8.7e-44 149.3 0.1 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PH PF00169.24 KFP07040.1 - 6e-15 55.3 0.5 2.1e-14 53.6 0.1 2.0 2 0 0 2 2 2 1 PH domain SH2 PF00017.19 KFP07040.1 - 3e-06 26.9 0.0 7.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PH_6 PF15406.1 KFP07040.1 - 0.0038 17.2 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain TMEM171 PF15471.1 KFP07040.1 - 1.3 7.7 3.9 2.8 6.6 2.7 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 EABR PF12180.3 KFP07041.1 - 1.8e-18 65.5 3.8 1.8e-18 65.5 2.6 2.6 2 1 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 FlxA PF14282.1 KFP07041.1 - 0.00015 21.7 4.1 0.00015 21.7 2.8 5.9 2 1 3 5 5 5 1 FlxA-like protein ATG16 PF08614.6 KFP07041.1 - 0.0012 18.7 15.8 0.0012 18.7 11.0 3.6 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) DUF1192 PF06698.6 KFP07041.1 - 0.031 14.0 0.3 0.031 14.0 0.2 4.9 5 1 1 6 6 6 0 Protein of unknown function (DUF1192) Filament PF00038.16 KFP07041.1 - 0.58 9.5 51.2 3.3 7.0 0.2 3.2 2 1 1 3 3 3 0 Intermediate filament protein Spc7 PF08317.6 KFP07041.1 - 6.2 5.3 51.4 0.32 9.6 12.7 3.7 3 1 1 4 4 4 0 Spc7 kinetochore protein zf-RING_2 PF13639.1 KFP07043.1 - 5.3e-14 51.7 8.2 7.9e-14 51.2 4.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP07043.1 - 3.2e-10 39.8 7.2 6.6e-10 38.8 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP07043.1 - 8.3e-10 38.1 6.4 1.6e-09 37.2 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP07043.1 - 1.2e-09 37.7 5.8 2.2e-09 36.8 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP07043.1 - 4.8e-09 35.7 6.6 9.7e-09 34.8 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFP07043.1 - 3.5e-06 26.5 3.7 9.3e-06 25.1 2.6 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KFP07043.1 - 4.3e-06 26.7 0.8 1e-05 25.5 0.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFP07043.1 - 3.8e-05 23.3 2.7 0.00023 20.7 1.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFP07043.1 - 0.00066 19.4 10.0 0.016 15.1 7.0 2.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KFP07043.1 - 0.0013 18.2 4.2 0.0025 17.3 0.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-UDP PF14569.1 KFP07043.1 - 0.014 15.1 2.1 0.014 15.1 1.5 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_6 PF14835.1 KFP07043.1 - 0.014 15.1 5.3 0.092 12.5 3.6 2.2 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Rtf2 PF04641.7 KFP07043.1 - 0.017 14.3 7.1 0.05 12.7 4.9 2.0 1 1 0 1 1 1 0 Rtf2 RING-finger DUF1272 PF06906.6 KFP07043.1 - 0.13 12.0 5.8 0.32 10.8 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-P11 PF03854.9 KFP07043.1 - 0.16 11.4 7.3 0.049 13.1 2.3 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-Apc11 PF12861.2 KFP07043.1 - 0.2 11.4 3.6 0.41 10.5 2.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 KFP07043.1 - 0.37 10.6 7.5 0.1 12.4 1.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Nse PF11789.3 KFP07043.1 - 0.86 9.1 7.1 1.8 8.1 3.8 2.4 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit BTV_NS2 PF04514.7 KFP07043.1 - 1.1 8.0 5.1 1.3 7.8 3.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FANCL_C PF11793.3 KFP07043.1 - 1.1 9.2 7.9 5.1 7.1 3.8 2.7 2 1 0 2 2 1 0 FANCL C-terminal domain zinc-ribbons_6 PF07191.7 KFP07043.1 - 1.4 8.7 7.2 6 6.7 5.0 2.1 1 1 0 1 1 1 0 zinc-ribbons DUF329 PF03884.9 KFP07043.1 - 3.8 7.1 7.4 3.8 7.1 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF329) Zn-ribbon_8 PF09723.5 KFP07043.1 - 5.5 7.0 7.3 4 7.4 2.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.16 KFP07043.1 - 7 6.6 13.1 3 7.8 4.8 2.7 2 1 1 3 3 3 0 FYVE zinc finger IBR PF01485.16 KFP07043.1 - 8.5 6.3 9.7 61 3.5 6.7 2.6 1 1 0 1 1 1 0 IBR domain GDPD PF03009.12 KFP07044.1 - 5 6.5 7.4 5.9 6.3 4.3 1.7 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family FYVE PF01363.16 KFP07045.1 - 1.4e-19 69.7 12.1 1.4e-19 69.7 8.4 3.1 3 1 0 3 3 3 1 FYVE zinc finger HAUS-augmin3 PF14932.1 KFP07046.1 - 5e-57 193.0 24.3 5e-57 193.0 16.9 3.9 2 2 2 4 4 4 1 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 KFP07046.1 - 0.023 14.5 18.1 0.041 13.7 1.7 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_pol_A PF00476.15 KFP07047.1 - 4.5e-81 272.4 0.9 6.2e-81 271.9 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase family A Acetyltransf_1 PF00583.19 KFP07048.1 - 7.5e-16 57.9 0.1 1e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFP07048.1 - 2.9e-11 43.3 0.0 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFP07048.1 - 1.5e-08 34.7 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFP07048.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFP07048.1 - 5.1e-06 26.2 0.0 1.6e-05 24.6 0.0 1.7 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KFP07048.1 - 1.5e-05 25.2 0.1 1.8e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFP07048.1 - 0.00016 21.6 0.0 0.00021 21.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFP07048.1 - 0.0021 17.7 1.0 0.0039 16.9 0.1 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 KFP07048.1 - 0.0056 16.5 0.3 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Neuropep_like PF15161.1 KFP07049.1 - 1.2e-28 98.3 0.2 1.4e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Neuropeptide-like Neuropep_like PF15161.1 KFP07050.1 - 3.7e-43 144.8 0.5 5.9e-43 144.1 0.4 1.3 1 0 0 1 1 1 1 Neuropeptide-like PWWP PF00855.12 KFP07051.1 - 4.4e-42 142.1 7.5 2.2e-22 79.0 1.4 3.5 2 0 0 2 2 2 2 PWWP domain SET PF00856.23 KFP07051.1 - 5.8e-26 91.7 0.5 5.8e-26 91.7 0.4 4.0 2 2 0 2 2 2 1 SET domain PHD PF00628.24 KFP07051.1 - 7.8e-18 63.9 63.9 7.3e-08 31.9 2.1 6.5 4 2 2 6 6 6 4 PHD-finger HMG_box PF00505.14 KFP07051.1 - 1.3e-11 44.5 0.1 5e-11 42.7 0.1 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box zf-HC5HC2H PF13771.1 KFP07051.1 - 1.1e-05 25.5 62.3 0.01 15.9 0.1 7.4 4 2 2 6 6 6 4 PHD-like zinc-binding domain SAF PF08666.7 KFP07051.1 - 0.19 12.1 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 SAF domain zf-HC5HC2H_2 PF13832.1 KFP07051.1 - 5.7 6.9 59.5 0.018 15.0 1.0 6.7 3 2 4 7 7 7 0 PHD-zinc-finger like domain LETM1 PF07766.8 KFP07052.1 - 7.6e-116 385.8 7.8 7.6e-116 385.8 5.4 3.2 2 1 2 4 4 4 1 LETM1-like protein EF-hand_7 PF13499.1 KFP07052.1 - 9.3e-06 25.6 0.4 0.001 19.1 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP07052.1 - 0.0068 16.1 0.1 1.7 8.7 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFP07052.1 - 0.01 15.4 0.5 0.19 11.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP07052.1 - 0.011 14.9 0.2 0.19 11.1 0.1 2.9 3 0 0 3 3 3 0 EF hand SAP PF02037.22 KFP07052.1 - 0.011 15.1 0.2 0.011 15.1 0.1 3.3 3 0 0 3 3 2 0 SAP domain MinC_N PF05209.8 KFP07052.1 - 0.018 14.8 0.7 1 9.1 0.0 3.4 3 0 0 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain EF-hand_5 PF13202.1 KFP07052.1 - 0.037 13.3 0.6 0.16 11.3 0.2 2.5 2 0 0 2 2 2 0 EF hand Acetyltransf_11 PF13720.1 KFP07052.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.2 4 0 0 4 4 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Cob_adeno_trans PF01923.13 KFP07052.1 - 4.6 7.0 11.9 6.2 6.5 4.4 3.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF3573 PF12097.3 KFP07052.1 - 8.2 4.9 6.9 36 2.7 3.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3573) Pkinase_Tyr PF07714.12 KFP07053.1 - 8e-104 346.2 0.0 1.3e-103 345.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP07053.1 - 3.9e-48 163.8 0.0 5.2e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.11 KFP07053.1 - 7.1e-37 125.1 0.0 4.5e-14 52.0 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP07053.1 - 4.4e-29 100.4 0.6 2.2e-09 37.2 0.0 3.7 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.20 KFP07053.1 - 3.4e-23 81.5 3.2 1.5e-06 28.2 0.0 4.0 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP07053.1 - 5.5e-22 78.0 1.6 7e-08 32.8 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP07053.1 - 1.5e-15 57.1 5.3 4.3e-05 23.3 0.0 5.6 4 2 0 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP07053.1 - 0.00036 20.3 0.4 0.021 14.7 0.0 3.2 2 1 2 4 4 4 1 CD80-like C2-set immunoglobulin domain V-set_CD47 PF08204.6 KFP07053.1 - 0.028 14.1 1.0 0.81 9.4 0.0 3.1 3 1 0 3 3 3 0 CD47 immunoglobulin-like domain Kinase-like PF14531.1 KFP07053.1 - 0.047 12.6 0.1 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Kinase-like TACC PF05010.9 KFP07054.1 - 8.1e-80 267.4 38.1 8.1e-80 267.4 26.4 1.8 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) HTH_37 PF13744.1 KFP07054.1 - 0.38 10.5 7.0 0.13 12.0 0.7 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain DUF1342 PF07072.6 KFP07054.1 - 1.2 8.7 13.6 0.027 14.1 1.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1342) DUF3584 PF12128.3 KFP07054.1 - 7.2 3.7 34.0 0.039 11.2 15.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Tmpp129 PF10272.4 KFP07055.1 - 2.5e-154 513.3 0.4 2.8e-154 513.1 0.3 1.0 1 0 0 1 1 1 1 Putative transmembrane protein precursor C1_4 PF07975.7 KFP07055.1 - 0.03 14.3 1.5 0.03 14.3 1.1 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3577 PF12101.3 KFP07055.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) zf-RING_2 PF13639.1 KFP07055.1 - 3.2 7.6 16.2 12 5.8 11.2 2.1 1 1 0 1 1 1 0 Ring finger domain SLBP_RNA_bind PF15247.1 KFP07056.1 - 2.1e-33 113.9 4.6 2.1e-33 113.9 3.2 1.7 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain SPATIAL PF15256.1 KFP07056.1 - 0.061 13.3 1.8 0.077 13.0 1.1 1.3 1 1 0 1 1 1 0 SPATIAL FAM53 PF15242.1 KFP07057.1 - 4.6e-120 400.9 19.4 5.8e-120 400.5 13.5 1.1 1 0 0 1 1 1 1 Family of FAM53 Phospholip_A2_3 PF09056.6 KFP07058.1 - 0.032 14.4 1.4 0.053 13.7 0.5 1.6 2 0 0 2 2 2 0 Prokaryotic phospholipase A2 Macro PF01661.16 KFP07058.1 - 0.1 12.5 1.3 0.39 10.6 0.2 2.0 2 0 0 2 2 2 0 Macro domain DUF4060 PF13269.1 KFP07058.1 - 0.11 12.4 0.3 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) Apolipoprotein PF01442.13 KFP07058.1 - 0.16 11.4 10.6 2.6 7.5 0.4 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain CLTH PF10607.4 KFP07059.1 - 4.8e-29 100.9 0.4 1.1e-28 99.8 0.3 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KFP07059.1 - 0.0021 17.7 0.8 0.053 13.2 0.0 2.9 2 0 0 2 2 2 1 RING-type zinc-finger LisH PF08513.6 KFP07059.1 - 0.096 12.4 0.5 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 LisH 2-Hacid_dh_C PF02826.14 KFP07060.1 - 4.1e-57 192.1 0.0 5.9e-57 191.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFP07060.1 - 1.7e-28 98.7 0.0 2.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFP07060.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 KFP07060.1 - 0.022 15.0 0.0 0.066 13.5 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Cellsynth_D PF03500.8 KFP07060.1 - 0.063 12.9 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Cellulose synthase subunit D Spond_N PF06468.8 KFP07062.1 - 1.5e-88 295.6 0.3 1.9e-88 295.2 0.2 1.1 1 0 0 1 1 1 1 Spondin_N TSP_1 PF00090.14 KFP07062.1 - 0.02 15.0 2.9 0.037 14.1 2.0 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 domain Neogenin_C PF06583.7 KFP07062.1 - 0.054 13.0 0.2 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 Neogenin C-terminus EMP24_GP25L PF01105.19 KFP07063.1 - 1.9e-45 154.8 0.6 2.1e-45 154.6 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF342 PF03961.8 KFP07063.1 - 0.017 13.5 0.4 0.022 13.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-RING_5 PF14634.1 KFP07064.1 - 1.2e-09 37.7 12.7 1.2e-09 37.7 8.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFP07064.1 - 0.0074 15.9 5.9 0.0074 15.9 4.1 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFP07064.1 - 0.011 15.7 13.3 0.011 15.7 9.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP07064.1 - 0.013 15.1 10.4 0.013 15.1 7.2 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3338 PF11819.3 KFP07064.1 - 0.022 14.2 1.6 0.034 13.5 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) Flp_N PF03930.9 KFP07064.1 - 0.024 14.3 0.8 0.038 13.7 0.6 1.3 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus IncA PF04156.9 KFP07064.1 - 0.12 11.9 3.6 0.17 11.4 2.5 1.1 1 0 0 1 1 1 0 IncA protein zf-RING_2 PF13639.1 KFP07064.1 - 0.22 11.4 13.9 0.42 10.4 8.1 2.4 1 1 1 2 2 2 0 Ring finger domain YlqD PF11068.3 KFP07064.1 - 0.56 10.2 5.2 0.78 9.7 3.6 1.2 1 0 0 1 1 1 0 YlqD protein zf-RING_6 PF14835.1 KFP07064.1 - 3.3 7.5 8.5 6.7 6.5 5.9 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2HC5 PF06221.8 KFP07064.1 - 3.4 7.5 11.8 12 5.7 8.2 2.1 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type I-set PF07679.11 KFP07065.1 - 1.7e-47 159.1 0.0 1e-17 63.7 0.0 3.4 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP07065.1 - 2.5e-30 104.3 0.0 3.3e-12 46.3 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.20 KFP07065.1 - 6.3e-23 80.6 0.1 5.8e-10 39.1 0.0 4.3 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.12 KFP07065.1 - 1.5e-19 69.9 0.9 6e-07 29.3 0.0 4.6 2 2 1 3 3 3 3 Immunoglobulin V-set domain Ig_3 PF13927.1 KFP07065.1 - 2.3e-19 69.6 0.1 8.1e-07 29.4 0.0 4.4 3 2 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.7 KFP07065.1 - 1.5e-06 28.0 0.3 0.00089 19.1 0.0 3.1 3 0 0 3 3 3 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 KFP07065.1 - 0.00048 20.0 0.0 2.8 7.8 0.0 3.2 3 0 0 3 3 3 1 Natural killer cell receptor 2B4 Herpes_gI PF01688.12 KFP07065.1 - 0.024 13.7 0.0 15 4.6 0.0 3.1 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein I V-set_CD47 PF08204.6 KFP07065.1 - 0.12 12.0 0.2 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain HLH PF00010.21 KFP07066.1 - 7.3e-06 25.5 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_transf_29 PF00777.13 KFP07067.1 - 2.2e-72 243.4 0.0 2.7e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) PPR_2 PF13041.1 KFP07068.1 - 1.2e-24 86.0 5.8 1.8e-07 30.9 0.1 7.7 7 1 1 8 8 8 3 PPR repeat family PPR_3 PF13812.1 KFP07068.1 - 2.4e-13 49.1 7.5 0.002 18.2 0.0 9.2 11 1 0 11 11 11 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFP07068.1 - 3.1e-06 26.5 0.6 4.9 6.7 0.3 6.5 6 2 0 6 6 6 2 PPR repeat PPR PF01535.15 KFP07068.1 - 1e-05 25.1 17.1 0.33 11.0 0.1 8.8 11 0 0 11 11 11 2 PPR repeat ECSIT PF06239.6 KFP07068.1 - 0.00046 19.1 0.3 0.91 8.3 0.2 2.9 3 0 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway Mitofilin PF09731.4 KFP07069.1 - 6.6e-176 586.4 37.1 8.7e-176 586.0 25.7 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein MRP-S23 PF10484.4 KFP07069.1 - 0.0084 16.0 0.1 0.058 13.2 0.1 2.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 Baculo_PEP_C PF04513.7 KFP07069.1 - 0.1 12.4 14.2 0.65 9.8 0.3 4.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L35p PF01632.14 KFP07070.1 - 1.3e-23 82.6 7.2 1.8e-23 82.1 5.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 DUF3437 PF11919.3 KFP07070.1 - 0.057 13.1 0.2 0.12 12.1 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) PMSR PF01625.16 KFP07070.1 - 0.11 12.4 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase IL33 PF15095.1 KFP07070.1 - 0.39 10.1 2.0 0.43 9.9 1.4 1.1 1 0 0 1 1 1 0 Interleukin 33 TB2_DP1_HVA22 PF03134.14 KFP07071.1 - 2.3e-31 107.3 10.8 3.4e-31 106.8 7.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2306 PF10067.4 KFP07071.1 - 0.03 14.4 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Halogen_Hydrol PF10112.4 KFP07071.1 - 0.066 12.6 0.1 0.093 12.1 0.1 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein JmjC PF02373.17 KFP07072.1 - 4.7e-12 46.1 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-UDP PF14569.1 KFP07072.1 - 2.9 7.7 6.9 0.37 10.5 1.2 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger Snf7 PF03357.16 KFP07073.1 - 2.5e-41 140.9 16.3 2.5e-41 140.9 11.3 1.3 2 0 0 2 2 2 1 Snf7 zf-ZPR1 PF03367.8 KFP07073.1 - 0.0061 15.7 1.1 0.0061 15.7 0.8 1.7 2 0 0 2 2 2 1 ZPR1 zinc-finger domain DUF3915 PF13054.1 KFP07073.1 - 0.093 12.6 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Cauli_AT PF03233.8 KFP07073.1 - 0.58 9.8 5.9 0.11 12.2 0.4 2.1 1 1 0 2 2 2 0 Aphid transmission protein IF3_C PF00707.17 KFP07073.1 - 1 9.1 6.7 0.11 12.1 1.1 2.0 2 1 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain DUF3818 PF12825.2 KFP07073.1 - 1.2 7.7 6.9 1.6 7.3 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) NPV_P10 PF05531.7 KFP07073.1 - 4.8 7.5 6.1 25 5.1 0.4 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-RING_2 PF13639.1 KFP07074.1 - 3.3e-11 42.8 10.9 3.3e-11 42.8 7.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP07074.1 - 8e-07 28.9 11.5 8e-07 28.9 7.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP07074.1 - 5.3e-06 25.9 8.2 1.4e-05 24.6 5.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP07074.1 - 1.4e-05 24.7 8.2 1.4e-05 24.7 5.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFP07074.1 - 4.2e-05 23.5 11.4 0.00012 22.1 7.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFP07074.1 - 0.0012 18.4 13.1 0.0012 18.4 9.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFP07074.1 - 0.004 16.9 8.6 0.01 15.6 6.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFP07074.1 - 0.049 13.3 5.1 0.066 12.9 2.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger CLTH PF10607.4 KFP07075.1 - 9.4e-31 106.4 0.0 1.7e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KFP07075.1 - 1.5e-18 66.2 1.0 3.5e-18 65.0 0.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFP07075.1 - 8.1e-05 22.3 0.2 0.00021 21.0 0.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.3 KFP07075.1 - 0.0068 15.9 1.2 0.016 14.7 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SnoaL_4 PF13577.1 KFP07075.1 - 0.02 14.8 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain zf-C3HC4_2 PF13923.1 KFP07075.1 - 0.093 12.7 0.1 0.093 12.7 0.1 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP07075.1 - 0.68 9.7 4.2 0.23 11.2 0.8 1.8 2 0 0 2 2 2 0 zinc-RING finger domain V-set PF07686.12 KFP07076.1 - 3.7e-14 52.5 0.3 4.6e-14 52.2 0.2 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFP07076.1 - 3.3e-09 36.7 1.1 4.7e-09 36.2 0.8 1.2 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP07076.1 - 0.0011 19.4 1.2 0.0017 18.8 0.8 1.3 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP07076.1 - 0.017 14.9 0.1 0.029 14.2 0.1 1.5 1 1 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP07076.1 - 0.028 14.5 0.8 0.049 13.7 0.6 1.5 1 1 0 1 1 1 0 Immunoglobulin domain zf-met PF12874.2 KFP07077.1 - 1.3e-27 95.1 18.4 1.2e-06 28.5 0.1 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP07077.1 - 3e-15 55.8 15.5 0.00048 20.1 0.1 4.4 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KFP07077.1 - 4.4e-09 35.7 17.1 0.0013 18.2 0.7 4.3 4 0 0 4 4 4 3 U1 zinc finger zf-C2H2_2 PF12756.2 KFP07077.1 - 0.00032 20.7 13.2 0.32 11.1 0.0 4.1 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) DUF2248 PF10005.4 KFP07077.1 - 0.019 13.8 7.3 0.75 8.6 5.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) C1_1 PF00130.17 KFP07077.1 - 0.24 11.1 9.5 4.1 7.2 0.1 3.6 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vps39_2 PF10367.4 KFP07077.1 - 0.65 10.2 7.6 8.9 6.5 4.1 2.8 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C2H2 PF00096.21 KFP07077.1 - 9.6 6.7 10.8 12 6.4 0.1 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-MYND PF01753.13 KFP07078.1 - 1.5e-09 37.5 17.9 1.5e-09 37.5 12.4 2.8 3 0 0 3 3 3 1 MYND finger SET PF00856.23 KFP07078.1 - 1.9e-09 38.0 0.5 1.8e-08 34.8 0.3 2.4 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 KFP07078.1 - 0.00018 21.3 0.9 0.01 15.7 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Lipocalin_7 PF14651.1 KFP07079.1 - 5.7e-35 119.8 4.1 6.4e-35 119.6 2.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin PF00061.18 KFP07079.1 - 6.5e-15 55.3 2.7 7.1e-15 55.2 1.9 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF669 PF05037.8 KFP07079.1 - 0.11 12.3 1.3 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF669) GTP_EFTU_D4 PF14578.1 KFP07079.1 - 0.82 9.3 4.9 11 5.7 0.2 2.2 1 1 0 2 2 2 0 Elongation factor Tu domain 4 Thr_synth_N PF14821.1 KFP07080.1 - 1.6e-24 85.7 0.0 6.4e-24 83.7 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KFP07080.1 - 5.2e-13 48.9 0.0 8.8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_56 PF07429.6 KFP07080.1 - 0.052 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Fork_head PF00250.13 KFP07081.1 - 0.00094 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Fork head domain 7tm_1 PF00001.16 KFP07082.1 - 1.1e-69 234.4 28.0 1.3e-69 234.2 19.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP07082.1 - 6.8e-08 31.9 32.7 7.1e-07 28.6 22.6 2.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP07082.1 - 4.2 6.3 33.7 13 4.7 22.5 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx Rib_5-P_isom_A PF06026.9 KFP07083.1 - 4.6e-57 192.0 0.1 6e-57 191.7 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) UPRTase PF14681.1 KFP07083.1 - 0.049 12.8 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Sugar-bind PF04198.8 KFP07083.1 - 0.056 12.3 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Peptidase_C93 PF06035.6 KFP07083.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP TBPIP_N PF15517.1 KFP07083.1 - 0.11 12.1 0.0 18 5.0 0.0 3.0 2 1 1 3 3 3 0 TBP-interacting protein N-terminus CoA_binding PF02629.14 KFP07084.1 - 7.1e-32 109.7 1.7 4.2e-31 107.3 0.1 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KFP07084.1 - 7e-23 80.9 0.0 1.2e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFP07084.1 - 2e-08 33.9 0.0 3.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KFP07084.1 - 1.9e-05 24.8 0.0 5.2e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain UQ_con PF00179.21 KFP07085.1 - 9.5e-46 154.7 0.0 1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFP07085.1 - 0.056 13.3 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain Ank_2 PF12796.2 KFP07086.1 - 2.9e-105 344.8 25.8 8.2e-19 67.7 0.0 11.5 4 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07086.1 - 1.5e-98 317.9 40.5 5.7e-12 44.8 0.0 22.1 22 1 0 22 22 22 17 Ankyrin repeat Ank_4 PF13637.1 KFP07086.1 - 5.6e-70 230.6 29.4 1.1e-07 32.2 0.0 18.2 6 6 13 19 19 19 15 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP07086.1 - 1.3e-69 228.6 33.1 3.3e-09 36.6 0.0 15.0 11 3 4 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07086.1 - 3.7e-66 212.4 30.1 6e-05 22.8 0.0 20.5 22 0 0 22 22 22 14 Ankyrin repeat FYVE PF01363.16 KFP07086.1 - 1.8e-16 59.8 9.8 4.2e-16 58.5 6.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger BTB PF00651.26 KFP07086.1 - 3e-15 56.1 0.1 1.1e-14 54.3 0.1 2.0 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 KFP07086.1 - 0.015 15.1 0.4 0.015 15.1 0.3 2.5 3 1 0 3 3 3 0 BTB And C-terminal Kelch FYVE_2 PF02318.11 KFP07086.1 - 1.1 9.2 12.2 0.31 10.9 5.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Sec2p PF06428.6 KFP07088.1 - 0.034 13.9 1.1 0.038 13.8 0.8 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Spc7 PF08317.6 KFP07088.1 - 0.054 12.1 1.0 0.055 12.1 0.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.7 KFP07088.1 - 0.071 12.9 3.9 0.17 11.7 0.7 2.6 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat Sec8_exocyst PF04048.9 KFP07088.1 - 0.13 11.9 0.8 0.13 11.9 0.6 1.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain E1-E2_ATPase PF00122.15 KFP07089.1 - 9.5e-68 227.6 1.9 2.2e-67 226.4 1.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFP07089.1 - 3.3e-44 150.5 4.0 3.3e-44 150.5 2.8 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFP07089.1 - 6.7e-31 108.3 0.0 3.2e-24 86.5 0.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP07089.1 - 1.2e-22 79.6 1.0 2.2e-22 78.8 0.7 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFP07089.1 - 5.5e-15 56.0 0.3 3e-14 53.6 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFP07089.1 - 7.4e-07 29.0 1.4 1.3e-06 28.1 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase P2X_receptor PF00864.14 KFP07090.1 - 1.2e-168 560.6 0.4 1.4e-168 560.3 0.2 1.0 1 0 0 1 1 1 1 ATP P2X receptor Pkinase PF00069.20 KFP07091.1 - 5.2e-66 222.4 0.0 8e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07091.1 - 6e-33 114.0 0.0 1e-30 106.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFP07091.1 - 2.4e-08 33.2 0.0 3.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP07091.1 - 0.2 11.3 0.4 0.53 9.9 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DER1 PF04511.10 KFP07092.1 - 7e-64 214.9 11.7 8e-64 214.7 8.1 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KFP07092.1 - 0.29 11.1 19.0 0.47 10.4 13.2 1.3 1 1 0 1 1 1 0 Rhomboid family DUF2304 PF10066.4 KFP07092.1 - 4.3 7.2 6.6 0.75 9.6 1.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) OB_NTP_bind PF07717.11 KFP07093.1 - 1.2e-22 79.8 0.0 2.3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFP07093.1 - 1.5e-22 79.5 0.0 3.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFP07093.1 - 5.1e-13 48.6 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFP07093.1 - 3.4e-06 26.6 0.8 2.1e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFP07093.1 - 0.011 15.8 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MAM33 PF02330.11 KFP07094.1 - 5.5e-70 235.2 4.5 6.1e-70 235.1 3.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF524 PF04411.7 KFP07094.1 - 0.0067 16.2 0.1 0.018 14.8 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF524) RPA_interact_C PF14768.1 KFP07095.1 - 2.8e-19 69.2 5.0 2.8e-19 69.2 3.5 2.0 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RPA_interact_M PF14767.1 KFP07095.1 - 5.4e-15 55.8 11.2 9.9e-15 55.0 7.8 1.5 1 0 0 1 1 1 1 Replication protein A interacting middle RPA_interact_N PF14766.1 KFP07095.1 - 2.3e-05 23.7 3.6 3.8e-05 23.0 2.5 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Cnd3 PF12719.2 KFP07095.1 - 0.036 13.0 0.7 0.047 12.6 0.5 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain FeThRed_B PF02943.10 KFP07095.1 - 0.045 13.4 0.5 0.045 13.4 0.3 2.0 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain Zn_Tnp_IS1595 PF12760.2 KFP07095.1 - 0.16 11.7 1.1 13 5.7 0.3 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_2 PF13639.1 KFP07095.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.7 2 1 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.1 KFP07095.1 - 0.2 11.4 1.9 0.5 10.1 0.9 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Rabaptin PF03528.10 KFP07096.1 - 1.9e-78 259.2 33.9 3.4e-43 145.8 12.2 9.5 4 3 2 6 6 6 3 Rabaptin Rab5-bind PF09311.6 KFP07096.1 - 8.2e-45 152.9 39.7 8.2e-45 152.9 27.5 5.7 3 1 1 5 5 5 2 Rabaptin-like protein Laminin_II PF06009.7 KFP07096.1 - 0.0061 16.3 8.6 0.0061 16.3 5.9 7.3 3 3 5 8 8 8 1 Laminin Domain II Fib_succ_major PF09603.5 KFP07096.1 - 0.11 13.0 0.1 0.11 13.0 0.1 3.3 3 2 0 3 3 3 0 Fibrobacter succinogenes major domain (Fib_succ_major) Rep_fac_C PF08542.6 KFP07097.1 - 3.1e-23 81.5 0.4 1.4e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 KFP07097.1 - 2.5e-13 50.3 0.1 4.2e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KFP07097.1 - 8.1e-12 45.1 0.0 1.7e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KFP07097.1 - 4.4e-07 29.8 0.0 7.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP07097.1 - 2.5e-06 27.5 0.0 0.00016 21.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFP07097.1 - 3.1e-06 27.3 0.3 0.00091 19.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFP07097.1 - 7.2e-06 25.6 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KFP07097.1 - 3.5e-05 23.4 0.0 7.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 KFP07097.1 - 8.4e-05 21.8 0.0 0.0011 18.1 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KFP07097.1 - 0.00012 21.5 0.1 0.095 12.1 0.0 2.5 1 1 1 2 2 2 2 AAA-like domain Rad17 PF03215.10 KFP07097.1 - 0.00031 19.5 0.1 0.27 9.8 0.0 2.4 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 KFP07097.1 - 0.00039 20.0 0.0 0.00059 19.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KFP07097.1 - 0.00043 19.8 0.9 0.083 12.3 0.0 2.9 1 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_18 PF13238.1 KFP07097.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 KFP07097.1 - 0.0013 17.8 0.1 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 KFP07097.1 - 0.0018 17.7 0.4 0.007 15.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFP07097.1 - 0.0021 17.1 0.0 0.005 15.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFP07097.1 - 0.003 17.2 0.0 0.0075 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KFP07097.1 - 0.0047 16.4 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 KFP07097.1 - 0.011 15.9 0.0 0.034 14.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KFP07097.1 - 0.014 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KFP07097.1 - 0.021 13.6 0.1 0.058 12.1 0.1 1.7 1 1 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 KFP07097.1 - 0.022 14.3 0.4 0.2 11.2 0.3 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFP07097.1 - 0.023 14.3 0.2 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 NTPase SNF2_N PF00176.18 KFP07097.1 - 0.027 13.2 0.1 5.7 5.6 0.0 2.3 1 1 1 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.4 KFP07097.1 - 0.03 13.3 0.4 0.3 10.0 0.3 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KFP07097.1 - 0.034 14.9 1.2 0.087 13.6 0.7 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFP07097.1 - 0.037 13.4 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFP07097.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFP07097.1 - 0.066 13.3 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase T2SE PF00437.15 KFP07097.1 - 0.082 11.7 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 KFP07097.1 - 0.094 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4597 PF15366.1 KFP07097.1 - 0.13 11.8 0.6 1.9 8.1 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4597) Auts2 PF15336.1 KFP07098.1 - 4.2e-107 356.9 17.7 4.2e-107 356.9 12.2 4.2 3 1 1 4 4 4 1 Autism susceptibility gene 2 protein ACT_7 PF13840.1 KFP07099.1 - 6.2e-35 118.5 0.0 1.3e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 ACT domain RCC1 PF00415.13 KFP07100.1 - 6.2e-60 199.2 16.7 7.6e-11 42.0 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFP07100.1 - 6.5e-26 89.3 38.8 7.7e-07 28.5 0.1 7.7 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SH3_1 PF00018.23 KFP07101.1 - 8.2e-30 101.9 0.9 1.5e-15 56.3 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 KFP07101.1 - 3.9e-25 87.1 0.5 2.8e-11 42.8 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 KFP07101.1 - 3e-21 74.6 0.0 8e-12 44.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain p47_phox_C PF08944.6 KFP07101.1 - 1.6e-16 60.1 3.6 1.6e-16 60.1 2.5 2.0 2 0 0 2 2 2 1 NADPH oxidase subunit p47Phox, C terminal domain PX PF00787.19 KFP07101.1 - 8.7e-16 57.7 1.3 8.7e-16 57.7 0.9 1.7 2 0 0 2 2 2 1 PX domain SH3_3 PF08239.6 KFP07101.1 - 0.00034 20.7 1.7 0.034 14.3 0.1 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_6 PF12913.2 KFP07101.1 - 0.062 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type GTF2I PF02946.9 KFP07102.1 - 1e-179 582.8 11.5 3.3e-30 103.7 0.1 6.2 6 0 0 6 6 6 6 GTF2I-like repeat Herpes_IE68 PF02479.11 KFP07102.1 - 0.016 14.4 2.5 1.7 7.8 0.1 4.2 5 0 0 5 5 5 0 Herpesvirus immediate early protein DUF1115 PF06544.7 KFP07102.1 - 0.23 11.1 4.8 1.3 8.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) GTF2I PF02946.9 KFP07103.1 - 6.3e-159 516.1 12.2 5.4e-32 109.4 0.0 5.3 5 0 0 5 5 5 5 GTF2I-like repeat CENP-P PF13096.1 KFP07103.1 - 0.061 12.6 1.8 3.4 6.9 0.2 3.7 4 0 0 4 4 4 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DUSP PF06337.7 KFP07103.1 - 0.079 13.3 0.0 42 4.6 0.0 3.4 4 0 0 4 4 4 0 DUSP domain SR-25 PF10500.4 KFP07103.1 - 2.1 7.7 20.3 0.056 12.8 9.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Lamprin PF06403.6 KFP07104.1 - 0.7 9.6 12.7 0.85 9.3 2.5 1.8 1 1 0 1 1 1 0 Lamprin CAP_GLY PF01302.20 KFP07105.1 - 3.8e-47 157.8 4.8 7.5e-24 83.2 0.2 2.3 2 0 0 2 2 2 2 CAP-Gly domain SBDS_C PF09377.5 KFP07106.1 - 1.7e-41 140.7 1.1 2.1e-41 140.5 0.8 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain DUF2407 PF10302.4 KFP07106.1 - 0.027 14.6 0.9 0.053 13.7 0.6 1.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Dehydratase_SU PF02287.10 KFP07106.1 - 0.029 14.1 0.2 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 Dehydratase small subunit DUF2356 PF10189.4 KFP07106.1 - 0.12 11.4 0.3 0.16 10.9 0.2 1.2 1 0 0 1 1 1 0 Conserved protein (DUF2356) Septin PF00735.13 KFP07107.1 - 1.1e-129 431.4 0.4 1.3e-129 431.2 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFP07107.1 - 2e-07 30.9 0.0 5e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP07107.1 - 1.8e-06 27.2 0.0 4.9e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFP07107.1 - 2.7e-06 26.9 0.1 0.002 17.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KFP07107.1 - 0.00026 20.1 0.1 0.00065 18.8 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 KFP07107.1 - 0.003 17.0 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Dynamin_N PF00350.18 KFP07107.1 - 0.0036 17.1 2.6 0.36 10.6 0.0 2.8 2 1 1 3 3 3 2 Dynamin family Ras PF00071.17 KFP07107.1 - 0.0041 16.5 0.1 0.012 14.9 0.0 1.8 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP07107.1 - 0.0054 17.2 0.2 0.042 14.3 0.0 2.3 2 1 1 3 3 3 1 Miro-like protein AAA_22 PF13401.1 KFP07107.1 - 0.0061 16.6 0.1 0.12 12.5 0.0 2.6 1 1 2 3 3 3 1 AAA domain ABC_tran PF00005.22 KFP07107.1 - 0.014 15.7 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KFP07107.1 - 0.03 13.8 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KFP07107.1 - 0.039 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CRISPR_Cas2 PF09827.4 KFP07107.1 - 0.055 13.6 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 CRISPR associated protein Cas2 FtsK_SpoIIIE PF01580.13 KFP07107.1 - 0.067 12.6 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Abhydrolase_6 PF12697.2 KFP07109.1 - 1e-09 38.6 0.0 1.2e-09 38.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP07109.1 - 2.5e-05 23.9 0.0 3.8e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2048 PF09752.4 KFP07109.1 - 0.0063 15.4 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Myotub-related PF06602.9 KFP07110.1 - 8e-145 482.0 0.0 1e-144 481.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KFP07110.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP07110.1 - 0.0049 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP07110.1 - 0.0073 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family zf-RING_2 PF13639.1 KFP07111.1 - 6e-15 54.7 9.1 6e-15 54.7 6.3 2.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFP07111.1 - 3.6e-08 33.3 8.7 3.6e-08 33.3 6.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP07111.1 - 2.3e-07 30.3 7.7 2.3e-07 30.3 5.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP07111.1 - 2.1e-06 27.6 7.3 2.1e-06 27.6 5.1 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP07111.1 - 4.1e-05 23.2 6.5 4.1e-05 23.2 4.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFP07111.1 - 0.00075 19.1 4.5 0.00075 19.1 3.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFP07111.1 - 0.044 13.7 4.2 0.12 12.3 2.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KFP07111.1 - 1.1 9.0 12.3 1.2 8.9 4.7 2.7 2 0 0 2 2 2 0 PHD-finger zf-Apc11 PF12861.2 KFP07111.1 - 9.5 6.1 14.4 0.27 11.0 4.8 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spt4 PF06093.8 KFP07112.1 - 1.2e-26 92.3 0.1 1.4e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Acyltransferase PF01553.16 KFP07113.1 - 2e-35 121.0 0.1 3.9e-35 120.1 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase An_peroxidase PF03098.10 KFP07114.1 - 3.1e-168 560.4 0.0 3.7e-168 560.2 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase IL8 PF00048.15 KFP07115.1 - 2.8e-23 81.6 0.1 2.8e-23 81.6 0.1 1.5 2 0 0 2 2 2 1 Small cytokines (intecrine/chemokine), interleukin-8 like ANTH PF07651.11 KFP07116.1 - 2.4e-73 246.2 8.1 4.8e-72 242.0 0.1 2.5 2 0 0 2 2 2 2 ANTH domain I_LWEQ PF01608.12 KFP07116.1 - 4e-58 195.6 8.4 4e-58 195.6 5.8 3.8 2 1 2 4 4 4 1 I/LWEQ domain ENTH PF01417.15 KFP07116.1 - 0.0049 16.7 0.6 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 ENTH domain IncA PF04156.9 KFP07116.1 - 1 8.9 72.7 1.6 8.2 22.9 3.5 2 1 1 3 3 3 0 IncA protein POM121 PF15229.1 KFP07117.1 - 8.9e-93 309.9 21.5 8.9e-93 309.9 14.9 3.1 3 0 0 3 3 3 1 POM121 family Nol1_Nop2_Fmu PF01189.12 KFP07118.1 - 1.2e-32 113.4 0.0 1.5e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KFP07118.1 - 0.00057 19.4 0.0 0.0032 17.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KFP07118.1 - 0.0024 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KFP07118.1 - 0.0029 17.6 0.1 0.0073 16.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF4415 PF14384.1 KFP07118.1 - 0.07 13.3 0.5 0.73 10.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4415) Ubie_methyltran PF01209.13 KFP07118.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPR_11 PF13414.1 KFP07119.1 - 3.3e-15 55.4 8.1 2e-08 33.7 0.3 2.3 1 1 1 2 2 2 2 TPR repeat FKBP_C PF00254.23 KFP07119.1 - 2.1e-12 46.8 0.0 6.1e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_12 PF13424.1 KFP07119.1 - 7e-11 41.9 4.4 6.4e-08 32.4 0.7 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP07119.1 - 5e-10 38.5 7.6 0.00067 19.3 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFP07119.1 - 7.1e-08 31.7 5.9 0.00095 18.6 0.2 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFP07119.1 - 3.4e-06 26.4 0.9 0.3 10.9 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP07119.1 - 1.8e-05 24.9 0.8 0.005 17.3 0.2 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KFP07119.1 - 9.7e-05 22.4 6.6 0.029 14.4 0.9 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KFP07119.1 - 0.0002 21.1 2.2 0.0049 16.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP07119.1 - 0.00031 20.3 2.0 0.15 11.9 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFP07119.1 - 0.0013 19.3 1.7 0.023 15.3 0.6 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP07119.1 - 0.0029 17.8 3.2 0.028 14.7 1.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFP07119.1 - 0.0068 16.2 3.7 0.59 10.0 0.1 2.8 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat Couple_hipA PF13657.1 KFP07119.1 - 0.036 14.3 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 HipA N-terminal domain Frizzled PF01534.12 KFP07120.1 - 6e-142 472.2 19.5 7.2e-142 471.9 13.5 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFP07120.1 - 0.0001 22.6 0.1 0.00026 21.3 0.1 1.7 1 0 0 1 1 1 1 Fz domain zf-DHHC PF01529.15 KFP07120.1 - 0.058 12.7 0.1 0.058 12.7 0.1 3.0 2 1 1 3 3 3 0 DHHC palmitoyltransferase Bromodomain PF00439.20 KFP07121.1 - 2.3e-22 78.7 0.1 5e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 Bromodomain WAC_Acf1_DNA_bd PF10537.4 KFP07121.1 - 1.7e-21 76.3 0.5 1.7e-21 76.3 0.3 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.24 KFP07121.1 - 5.3e-11 42.0 2.1 1.7e-10 40.3 1.4 1.9 1 0 0 1 1 1 1 PHD-finger WHIM2 PF15613.1 KFP07121.1 - 2.1e-08 33.7 0.3 5.1e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 KFP07121.1 - 4.6e-06 26.2 0.1 1.8e-05 24.4 0.1 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 KFP07121.1 - 6e-05 22.7 0.2 0.00028 20.5 0.1 2.2 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 PHD_2 PF13831.1 KFP07121.1 - 0.0042 16.3 0.5 0.01 15.1 0.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 KFP07121.1 - 0.056 13.2 2.3 0.15 11.9 1.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.1 KFP07121.1 - 0.28 10.9 3.5 0.47 10.2 0.7 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger HLH PF00010.21 KFP07122.1 - 1.4e-13 50.3 1.7 2.2e-13 49.6 0.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 KFP07122.1 - 0.15 12.3 2.2 0.2 11.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 KFP07122.1 - 0.33 10.4 3.2 0.63 9.5 2.2 1.4 1 0 0 1 1 1 0 Septum formation initiator WD40 PF00400.27 KFP07123.1 - 3.3e-22 77.4 4.4 1.6e-08 34.0 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KFP07123.1 - 0.016 14.9 0.0 0.33 10.6 0.0 2.7 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A BNIP3 PF06553.7 KFP07124.1 - 1.2 8.5 10.2 0.6 9.4 5.8 1.4 1 1 0 1 1 1 0 BNIP3 AAA_4 PF04326.9 KFP07125.1 - 3.2e-17 62.8 0.2 1.5e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 Divergent AAA domain DUF2075 PF09848.4 KFP07125.1 - 2.3e-06 26.8 0.0 5.7e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 KFP07125.1 - 7.5e-05 22.8 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 KFP07125.1 - 0.0004 19.6 0.0 0.31 10.2 0.0 2.4 1 1 1 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 KFP07125.1 - 0.0019 18.3 0.2 0.51 10.4 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 KFP07125.1 - 0.0038 17.4 0.0 0.053 13.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFP07125.1 - 0.0045 16.8 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFP07125.1 - 0.039 14.7 0.0 0.21 12.4 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFP07125.1 - 0.092 12.1 0.0 8.8 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain ResIII PF04851.10 KFP07125.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KFP07125.1 - 0.17 11.6 0.0 0.83 9.4 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Syntaxin PF00804.20 KFP07126.1 - 4.7e-48 161.6 8.0 4.7e-48 161.6 5.5 2.5 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 KFP07126.1 - 1.1e-24 85.9 1.5 1.1e-24 85.9 1.1 3.2 3 1 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 KFP07126.1 - 5.1e-06 26.4 13.1 2e-05 24.5 6.1 3.1 2 2 1 3 3 3 1 Syntaxin-like protein GNVR PF13807.1 KFP07126.1 - 0.0041 16.8 0.1 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase MCPsignal PF00015.16 KFP07126.1 - 0.0074 15.8 7.6 0.22 11.0 0.6 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF148 PF02520.12 KFP07126.1 - 0.0075 16.0 1.5 0.0075 16.0 1.0 2.5 3 0 0 3 3 2 1 Domain of unknown function DUF148 Laminin_II PF06009.7 KFP07126.1 - 0.0096 15.6 1.6 0.0096 15.6 1.1 2.4 2 1 0 2 2 2 1 Laminin Domain II DUF948 PF06103.6 KFP07126.1 - 0.027 14.3 3.0 5.4 6.9 0.4 3.7 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SIMPL PF04402.9 KFP07126.1 - 0.052 13.3 2.3 0.11 12.3 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Ferritin PF00210.19 KFP07126.1 - 0.059 13.1 3.5 0.034 13.8 0.8 1.8 2 0 0 2 2 2 0 Ferritin-like domain Lzipper-MIP1 PF14389.1 KFP07126.1 - 0.064 13.3 2.7 0.12 12.5 0.0 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ApoLp-III PF07464.6 KFP07126.1 - 0.065 13.2 10.0 0.074 13.0 2.9 2.9 1 1 2 3 3 2 0 Apolipophorin-III precursor (apoLp-III) WXG100 PF06013.7 KFP07126.1 - 0.071 13.1 2.8 2.3 8.3 0.1 3.4 4 0 0 4 4 3 0 Proteins of 100 residues with WXG DUF966 PF06136.8 KFP07126.1 - 0.13 11.6 8.6 0.13 11.6 5.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF966) DUF479 PF04336.7 KFP07126.1 - 0.15 12.1 3.2 12 6.0 0.1 3.0 1 1 0 2 2 2 0 Protein of unknown function, DUF479 AATF-Che1 PF13339.1 KFP07126.1 - 0.25 11.4 10.1 0.23 11.5 4.2 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor PspA_IM30 PF04012.7 KFP07126.1 - 0.31 10.3 10.4 0.06 12.7 3.4 2.2 2 1 1 3 3 3 0 PspA/IM30 family DUF1664 PF07889.7 KFP07126.1 - 0.33 10.7 11.7 0.45 10.3 2.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) ETRAMP PF09716.5 KFP07126.1 - 0.48 10.4 4.5 0.57 10.1 0.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Med9 PF07544.8 KFP07126.1 - 0.57 9.9 7.6 0.36 10.6 0.7 3.2 2 2 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LOH1CR12 PF10158.4 KFP07126.1 - 0.58 9.9 7.7 4.8 6.9 0.5 2.6 2 1 0 2 2 2 0 Tumour suppressor protein Syntaxin-6_N PF09177.6 KFP07126.1 - 0.63 10.4 12.6 0.25 11.7 2.6 3.1 2 1 1 3 3 2 0 Syntaxin 6, N-terminal Filo_VP35 PF02097.10 KFP07126.1 - 0.63 9.1 5.8 0.33 10.0 0.5 2.1 1 1 1 2 2 2 0 Filoviridae VP35 HAUS6_N PF14661.1 KFP07126.1 - 0.74 9.1 6.3 1.1 8.5 0.3 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.8 KFP07126.1 - 0.75 8.1 14.4 0.08 11.3 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 KFP07126.1 - 0.76 9.7 16.4 1.3 8.9 2.2 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ISG65-75 PF11727.3 KFP07126.1 - 0.84 8.6 11.0 0.028 13.4 2.0 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Phage_GPO PF05929.6 KFP07126.1 - 0.95 8.6 9.2 0.91 8.7 2.9 2.6 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF745 PF05335.8 KFP07126.1 - 1.1 8.6 6.7 2.9 7.3 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) MRC1 PF09444.5 KFP07126.1 - 1.3 9.3 9.2 3.1 8.1 6.4 1.7 1 0 0 1 1 1 0 MRC1-like domain COG5 PF10392.4 KFP07126.1 - 1.4 8.8 9.1 2.2 8.2 0.5 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 CorA PF01544.13 KFP07126.1 - 2.3 7.1 10.5 0.55 9.2 0.9 2.8 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF883 PF05957.8 KFP07126.1 - 3.6 8.0 8.2 4.2 7.8 0.8 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4404 PF14357.1 KFP07126.1 - 3.7 8.0 9.6 2.6 8.5 2.1 3.5 1 1 4 5 5 4 0 Domain of unknown function (DUF4404) Ead_Ea22 PF13935.1 KFP07126.1 - 3.9 7.7 12.5 2.8 8.2 3.4 2.6 2 2 0 2 2 2 0 Ead/Ea22-like protein Dna2 PF08696.6 KFP07126.1 - 4 6.7 10.1 1.3 8.2 0.9 2.5 1 1 0 2 2 2 0 DNA replication factor Dna2 DUF2203 PF09969.4 KFP07126.1 - 4.7 7.4 11.2 15 5.7 2.9 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.6 KFP07126.1 - 5.1 6.9 13.4 15 5.4 3.9 3.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UBN2 PF14223.1 KFP07126.1 - 5.2 6.8 12.3 0.53 10.0 1.6 2.9 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type APG6 PF04111.7 KFP07126.1 - 5.4 5.9 15.3 0.4 9.6 6.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 TBPIP PF07106.8 KFP07126.1 - 6.5 6.2 17.1 0.28 10.7 4.3 2.5 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Erp_C PF06780.6 KFP07126.1 - 7.6 6.3 13.6 3 7.6 6.1 2.5 2 2 0 2 2 1 0 Erp protein C-terminus YtxH PF12732.2 KFP07126.1 - 8.9 6.7 10.3 50 4.3 5.3 3.3 1 1 1 2 2 2 0 YtxH-like protein WBS_methylT PF12589.3 KFP07127.1 - 1.3e-22 80.0 4.2 1.9e-22 79.5 2.9 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KFP07127.1 - 1.6e-10 41.3 0.0 2.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP07127.1 - 5.3e-06 26.7 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP07127.1 - 6e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP07127.1 - 0.00011 22.7 0.0 0.00017 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP07127.1 - 0.00015 21.4 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP07127.1 - 0.00063 20.1 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP07127.1 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Fibrinogen_C PF00147.13 KFP07128.1 - 8.7e-27 94.2 0.2 9.5e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain EF-hand_1 PF00036.27 KFP07129.1 - 9.6e-18 62.0 6.6 8.1e-09 34.1 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 KFP07129.1 - 1.7e-16 60.1 1.9 1e-13 51.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP07129.1 - 4.6e-15 54.0 2.4 3.4e-08 32.7 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFP07129.1 - 2.2e-13 49.6 8.6 1.1e-10 40.9 0.2 4.1 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP07129.1 - 4.5e-13 47.8 9.1 6.9e-06 25.1 0.0 4.1 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 KFP07129.1 - 0.0024 17.8 0.2 0.0095 15.9 0.0 2.1 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFP07129.1 - 0.0068 16.1 0.1 0.018 14.7 0.1 1.7 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFP07129.1 - 0.0075 16.1 0.0 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 KFP07129.1 - 0.042 13.8 0.2 0.24 11.4 0.0 2.3 2 1 0 2 2 2 0 Ca2+ insensitive EF hand Glycos_transf_2 PF00535.21 KFP07130.1 - 6.6e-27 94.2 0.0 1.2e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP07130.1 - 1.4e-18 67.1 0.1 2.3e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFP07130.1 - 2.9e-07 30.5 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFP07130.1 - 2.9e-06 26.5 0.0 4.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFP07130.1 - 0.00069 19.0 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.1 KFP07130.1 - 0.043 14.1 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like I-set PF07679.11 KFP07131.1 - 3.9e-82 270.2 1.2 2.3e-19 69.0 0.1 5.7 5 0 0 5 5 5 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP07131.1 - 2.5e-48 162.1 0.1 6.6e-10 38.9 0.0 5.4 5 0 0 5 5 5 5 Immunoglobulin domain ig PF00047.20 KFP07131.1 - 5.2e-38 128.9 0.5 2.3e-07 30.8 0.0 6.5 7 1 0 7 7 6 5 Immunoglobulin domain Ig_3 PF13927.1 KFP07131.1 - 2.5e-33 114.3 1.4 2.6e-06 27.8 0.0 6.0 5 0 0 5 5 5 5 Immunoglobulin domain V-set PF07686.12 KFP07131.1 - 1.9e-31 108.2 0.7 1.3e-05 25.0 0.0 6.1 5 1 0 5 5 5 5 Immunoglobulin V-set domain fn3 PF00041.16 KFP07131.1 - 2.1e-30 104.6 2.6 2.8e-17 62.6 0.7 2.6 2 0 0 2 2 2 2 Fibronectin type III domain C2-set_2 PF08205.7 KFP07131.1 - 3.7e-13 49.1 1.4 0.0025 17.6 0.0 5.4 5 0 0 5 5 5 3 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.3 KFP07131.1 - 4.9e-06 26.4 1.5 2.7 7.9 0.0 5.3 6 1 0 6 6 6 3 Natural killer cell receptor 2B4 Herpes_gE PF02480.11 KFP07131.1 - 9.2e-06 24.1 0.2 0.17 10.1 0.0 3.8 1 1 2 4 4 4 2 Alphaherpesvirus glycoprotein E Interfer-bind PF09294.5 KFP07131.1 - 0.0006 19.8 0.0 0.1 12.6 0.0 2.9 2 0 0 2 2 2 1 Interferon-alpha/beta receptor, fibronectin type III C1-set PF07654.10 KFP07131.1 - 0.0011 18.9 0.0 1.8 8.6 0.0 3.9 4 0 0 4 4 4 1 Immunoglobulin C1-set domain C2-set PF05790.10 KFP07131.1 - 0.045 13.7 0.3 7.8 6.5 0.0 4.4 5 0 0 5 5 5 0 Immunoglobulin C2-set domain Yae1_N PF09811.4 KFP07132.1 - 1.6e-18 65.8 60.2 0.00046 19.6 5.3 5.4 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Hormone_recep PF00104.25 KFP07133.1 - 1.2e-41 142.0 0.1 1.7e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP07133.1 - 6.5e-31 106.3 17.1 6.5e-31 106.3 11.8 1.7 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) Arrestin_C PF02752.17 KFP07134.1 - 8e-21 74.5 0.1 1e-19 70.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KFP07134.1 - 6e-17 61.8 0.1 5e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.10 KFP07134.1 - 0.095 11.4 0.0 0.15 10.8 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Sulfotransfer_2 PF03567.9 KFP07135.1 - 2.8e-33 115.6 1.2 3.6e-33 115.3 0.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 KFP07135.1 - 3.9e-08 32.3 0.3 5.4e-08 31.8 0.2 1.2 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase RNA_pol_Rpb1_1 PF04997.7 KFP07136.1 - 1.8e-49 168.8 0.0 1.9e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 ANF_receptor PF01094.23 KFP07137.1 - 1.1e-32 113.2 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region TrkA_N PF02254.13 KFP07137.1 - 0.081 12.9 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Glyco_trans_4_4 PF13579.1 KFP07137.1 - 0.14 12.2 14.6 0.07 13.2 2.3 2.8 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain HNOBA PF07701.9 KFP07138.1 - 2.7e-07 30.0 0.5 3.1e-07 29.8 0.3 1.0 1 0 0 1 1 1 1 Heme NO binding associated KOW PF00467.24 KFP07140.1 - 0.00074 19.1 0.2 0.0011 18.5 0.2 1.3 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KFP07140.1 - 0.0064 16.3 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain LRR_8 PF13855.1 KFP07141.1 - 1.3e-20 72.8 14.2 1.1e-13 50.6 1.7 2.9 2 1 1 3 3 3 2 Leucine rich repeat 7tm_2 PF00002.19 KFP07141.1 - 4.2e-14 52.2 6.2 8.3e-14 51.2 4.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) I-set PF07679.11 KFP07141.1 - 1e-07 31.7 0.0 2.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin I-set domain GPS PF01825.16 KFP07141.1 - 8e-07 29.0 0.1 8e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Latrophilin/CL-1-like GPS domain LRR_4 PF12799.2 KFP07141.1 - 1.5e-05 24.4 12.5 0.00061 19.3 4.0 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP07141.1 - 0.00049 19.8 0.9 0.0032 17.1 0.0 2.6 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP07141.1 - 0.013 15.4 12.4 0.17 12.0 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.1 KFP07141.1 - 0.052 13.6 4.1 1.4 9.2 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat LRR_7 PF13504.1 KFP07141.1 - 4.6 7.8 8.5 3.1 8.4 0.1 3.7 3 0 0 3 3 3 0 Leucine rich repeat Sulfotransfer_1 PF00685.22 KFP07142.1 - 4.1e-33 114.7 0.1 5.6e-33 114.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.9 KFP07142.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family DNA_pol_lambd_f PF10391.4 KFP07143.1 - 1.6e-20 72.3 0.1 3.2e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KFP07143.1 - 3.3e-20 71.5 0.1 8.1e-20 70.2 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KFP07143.1 - 2.5e-13 49.9 0.0 6.6e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 KFP07143.1 - 2.1e-08 34.1 0.0 5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm BRCT PF00533.21 KFP07143.1 - 2.7e-06 27.4 0.0 7.8e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 KFP07143.1 - 3e-06 27.4 0.0 7.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.3 KFP07143.1 - 0.039 13.8 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus PTCB-BRCT PF12738.2 KFP07143.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain SH2 PF00017.19 KFP07144.1 - 1.6e-10 40.6 0.1 5.7e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 SH2 domain DUF2862 PF11061.3 KFP07144.1 - 0.064 12.9 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) zf-H2C2_2 PF13465.1 KFP07145.1 - 0.034 14.4 45.4 0.21 11.9 1.1 7.9 7 0 0 7 7 7 0 Zinc-finger double domain zf-C2H2 PF00096.21 KFP07145.1 - 0.06 13.7 53.5 0.25 11.7 0.9 8.0 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07145.1 - 1.5 9.3 51.4 0.5 10.8 0.1 8.3 7 1 1 8 8 8 0 C2H2-type zinc finger PhnA_Zn_Ribbon PF08274.7 KFP07145.1 - 3.5 7.5 9.4 0.17 11.7 1.5 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Cyclin_C PF02984.14 KFP07146.1 - 9.4e-26 90.0 11.7 3.4e-25 88.2 0.3 3.1 2 1 1 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 KFP07146.1 - 2.8e-18 65.6 0.9 2.8e-18 65.6 0.6 2.7 3 1 1 4 4 4 1 Cyclin, N-terminal domain DUF3535 PF12054.3 KFP07149.1 - 2.2e-138 461.5 7.8 9.9e-137 456.1 3.7 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KFP07149.1 - 1.8e-56 191.1 0.0 6.7e-56 189.2 0.0 2.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.17 KFP07149.1 - 5.8e-22 75.7 20.5 0.0021 17.9 0.0 12.9 12 0 0 12 12 12 6 HEAT repeat HEAT_2 PF13646.1 KFP07149.1 - 3.3e-15 56.1 0.7 0.00086 19.5 0.1 7.4 4 2 4 8 8 8 6 HEAT repeats Helicase_C PF00271.26 KFP07149.1 - 4e-13 49.0 0.0 9.8e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KFP07149.1 - 5.7e-12 45.8 0.2 0.0089 16.3 0.0 5.6 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFP07149.1 - 7.9e-11 42.1 8.4 0.0042 17.5 0.1 9.0 8 2 1 9 9 9 1 HEAT-like repeat Arm PF00514.18 KFP07149.1 - 0.018 14.8 4.7 0.14 12.0 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RRM_1 PF00076.17 KFP07150.1 - 2.4e-12 46.2 0.0 3.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07150.1 - 6.1e-07 29.3 0.0 2.2e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.7 KFP07150.1 - 0.03 13.8 0.6 0.071 12.6 0.4 1.6 1 0 0 1 1 1 0 U1 zinc finger HSP20 PF00011.16 KFP07150.1 - 0.11 12.3 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Hsp20/alpha crystallin family zf-B_box PF00643.19 KFP07150.1 - 0.11 12.4 6.3 0.24 11.2 4.4 1.5 1 0 0 1 1 1 0 B-box zinc finger SKG6 PF08693.5 KFP07150.1 - 0.84 9.0 2.5 1.7 7.9 1.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RINGv PF12906.2 KFP07151.1 - 5e-14 52.0 9.9 7.5e-14 51.5 6.9 1.3 1 0 0 1 1 1 1 RING-variant domain DUF2517 PF10725.4 KFP07151.1 - 0.00038 20.0 0.1 0.0009 18.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) zf-RING_2 PF13639.1 KFP07151.1 - 0.00055 19.7 6.0 0.0012 18.6 4.2 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KFP07151.1 - 0.034 14.0 5.7 0.075 13.0 3.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KFP07151.1 - 0.28 10.8 4.9 0.6 9.7 3.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CSL PF05207.8 KFP07151.1 - 0.51 9.8 3.4 1.7 8.2 2.4 1.8 1 1 0 1 1 1 0 CSL zinc finger PHD PF00628.24 KFP07151.1 - 2.3 8.0 8.3 3.9 7.2 5.8 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_M16 PF00675.15 KFP07152.1 - 4.2e-48 162.8 0.2 3.6e-46 156.6 0.1 2.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFP07152.1 - 2.1e-37 128.5 0.4 1.3e-21 77.1 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Sorb PF02208.11 KFP07152.1 - 0.17 11.2 0.3 0.53 9.7 0.2 1.8 1 0 0 1 1 1 0 Sorbin homologous domain Kinesin PF00225.18 KFP07153.1 - 1.4e-115 385.5 0.1 1.4e-115 385.5 0.0 3.3 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bind PF13931.1 KFP07153.1 - 6.3e-40 136.6 3.1 6.3e-40 136.6 2.2 5.0 4 2 0 5 5 5 1 Kinesin-associated microtubule-binding Homeobox PF00046.24 KFP07154.1 - 0.00029 20.4 7.3 0.00029 20.4 5.1 1.8 2 0 0 2 2 2 1 Homeobox domain Pox_Ag35 PF03286.9 KFP07154.1 - 0.63 9.5 3.7 0.73 9.3 2.6 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein p450 PF00067.17 KFP07156.1 - 2.3e-56 191.2 0.0 3.9e-56 190.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFP07157.1 - 2.3e-58 197.8 0.1 6.8e-52 176.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 EABR PF12180.3 KFP07158.1 - 6.8e-18 63.7 1.9 1.8e-17 62.3 1.3 1.8 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 ADIP PF11559.3 KFP07158.1 - 0.53 10.1 64.7 0.23 11.3 10.8 4.5 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Methyltrn_RNA_4 PF09936.4 KFP07158.1 - 6.7 6.1 6.6 0.52 9.7 0.6 2.2 2 2 0 2 2 2 0 SAM-dependent RNA methyltransferase Reo_sigmaC PF04582.7 KFP07158.1 - 8.9 5.3 10.3 3.1 6.8 1.2 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Lipocalin PF00061.18 KFP07159.1 - 3e-24 85.6 0.0 4.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.7 KFP07159.1 - 8.5e-07 28.8 0.3 1.4e-06 28.1 0.2 1.3 1 1 0 1 1 1 1 Lipocalin-like domain Triabin PF03973.8 KFP07159.1 - 1.8e-05 24.4 0.9 5.1e-05 22.9 0.6 1.7 1 1 0 1 1 1 1 Triabin PDEase_I PF00233.14 KFP07160.1 - 6e-91 304.3 2.8 6e-91 304.3 1.9 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 KFP07160.1 - 1.9e-33 115.7 0.0 1.7e-16 60.6 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 KFP07160.1 - 5.6e-11 42.6 0.0 3.1e-06 27.2 0.0 2.6 2 1 0 2 2 2 2 GAF domain GAF_2 PF13185.1 KFP07160.1 - 1.6e-07 31.9 0.0 0.0007 20.1 0.0 2.4 2 0 0 2 2 2 2 GAF domain Fra10Ac1 PF09725.4 KFP07161.1 - 1.1e-52 177.0 4.9 1.1e-52 177.0 3.4 1.8 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 Neur_chan_memb PF02932.11 KFP07161.1 - 1.6 8.5 6.2 0.16 11.8 1.2 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FYDLN_acid PF09538.5 KFP07161.1 - 7.9 7.1 16.6 0.51 10.9 5.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) EPTP PF03736.12 KFP07162.1 - 6.7e-95 310.6 20.7 1.1e-15 57.0 0.0 7.2 7 0 0 7 7 7 7 EPTP domain LRR_8 PF13855.1 KFP07162.1 - 5.8e-23 80.4 9.5 2.6e-15 55.9 3.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFP07162.1 - 3.8e-10 39.1 6.1 2.4e-05 23.8 1.4 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP07162.1 - 5.7e-08 32.5 0.9 5.7e-08 32.5 0.6 2.1 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP07162.1 - 3.8e-06 26.1 9.7 0.006 16.4 0.4 4.8 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.1 KFP07162.1 - 0.07 12.6 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 KFP07162.1 - 0.14 12.4 4.6 5.9 7.5 0.4 3.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 KFP07162.1 - 3.6 7.9 6.6 39 4.7 0.3 3.8 3 0 0 3 3 3 0 Leucine Rich repeat PI-PLC-Y PF00387.14 KFP07164.1 - 6.2e-34 116.5 0.0 1.5e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RA PF00788.18 KFP07164.1 - 4.3e-25 88.0 0.1 9.2e-19 67.7 0.1 2.5 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain C2 PF00168.25 KFP07164.1 - 4.4e-10 39.2 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain CBF PF03914.12 KFP07165.1 - 5e-38 130.1 0.2 5e-38 130.1 0.1 2.3 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 KFP07165.1 - 9.9e-33 112.2 2.9 9.9e-33 112.2 2.0 3.2 3 0 0 3 3 3 1 Nucleolar complex-associated protein PIN_3 PF13470.1 KFP07165.1 - 1.1 9.9 4.4 3.4 8.3 0.5 2.8 2 0 0 2 2 2 0 PIN domain RabGAP-TBC PF00566.13 KFP07166.1 - 2.3e-47 161.2 0.0 4e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 KFP07167.1 - 3.2e-135 440.8 51.4 3.1e-23 81.9 2.4 9.6 3 3 6 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07167.1 - 3.7e-135 433.5 47.4 6.7e-12 44.5 0.2 18.4 20 0 0 20 20 20 15 Ankyrin repeat Ank_5 PF13857.1 KFP07167.1 - 1.6e-107 349.0 49.4 3.5e-14 52.4 0.2 15.9 5 5 13 18 18 18 15 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP07167.1 - 3.4e-107 349.1 23.9 4.1e-14 52.6 0.2 14.7 7 5 7 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07167.1 - 4e-95 302.0 31.7 2e-07 30.5 0.1 18.2 20 0 0 20 20 20 15 Ankyrin repeat PARP PF00644.15 KFP07167.1 - 9.1e-27 93.8 3.8 2.6e-24 85.8 2.6 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_2 PF07647.12 KFP07167.1 - 1.4e-13 50.4 0.1 3.5e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP07167.1 - 3.9e-11 42.9 0.2 9.5e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Shigella_OspC PF06128.6 KFP07167.1 - 4.9e-06 26.2 0.0 1.5 8.2 0.0 4.8 4 0 0 4 4 4 1 Shigella flexneri OspC protein Vps39_1 PF10366.4 KFP07167.1 - 0.00018 21.4 1.0 1 9.4 0.0 3.6 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 CBM_21 PF03370.8 KFP07168.1 - 2.6e-36 124.0 2.6 4.3e-36 123.3 1.8 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KFP07168.1 - 0.00097 19.1 0.5 0.0025 17.8 0.4 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) HECT PF00632.20 KFP07170.1 - 1.1e-84 284.3 0.4 1.6e-84 283.8 0.3 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CENP-B_dimeris PF09026.5 KFP07170.1 - 0.27 11.4 2.6 0.74 10.0 1.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C3HC4 PF00097.20 KFP07171.1 - 4.5e-08 32.6 11.5 4.5e-08 32.6 8.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP07171.1 - 4.1e-07 29.9 11.1 4.1e-07 29.9 7.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP07171.1 - 2.5e-05 24.0 9.5 2.5e-05 24.0 6.6 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KFP07171.1 - 0.00011 21.7 10.5 0.00011 21.7 7.3 3.2 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFP07171.1 - 0.00013 21.7 10.5 0.00013 21.7 7.3 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KFP07171.1 - 0.0019 17.8 8.4 0.0019 17.8 5.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KFP07171.1 - 0.0048 16.3 7.5 0.0091 15.5 5.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KFP07171.1 - 0.025 14.3 2.9 0.025 14.3 2.0 2.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFP07171.1 - 0.13 12.0 9.8 0.045 13.4 4.3 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Zn_Tnp_IS1595 PF12760.2 KFP07171.1 - 0.19 11.5 0.2 0.19 11.5 0.2 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-rbx1 PF12678.2 KFP07171.1 - 3.2 7.9 12.7 1.7 8.8 6.0 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger Ank_2 PF12796.2 KFP07172.1 - 3.5e-36 123.4 0.8 2.8e-21 75.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07172.1 - 8.3e-35 116.8 1.3 3.7e-09 35.9 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFP07172.1 - 3.4e-29 100.6 0.3 3.3e-10 40.1 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP07172.1 - 6.7e-29 99.2 2.4 5.2e-08 32.8 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07172.1 - 2.1e-25 86.2 0.0 6.6e-06 25.8 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat RRM_3 PF08777.6 KFP07172.1 - 0.16 11.8 2.8 0.33 10.8 2.0 1.5 1 0 0 1 1 1 0 RNA binding motif RNase_P_p30 PF01876.11 KFP07173.1 - 5e-51 171.8 0.0 6.3e-51 171.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 PTS_EIIA_2 PF00359.17 KFP07173.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.8 2 1 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7tm_1 PF00001.16 KFP07174.1 - 8.4e-82 274.1 13.2 9.9e-82 273.9 9.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP07174.1 - 3.5e-09 36.1 12.6 6.1e-09 35.4 8.8 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP07174.1 - 0.011 14.8 16.0 0.0075 15.4 9.4 2.1 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4491 PF14898.1 KFP07174.1 - 2.1 8.5 7.4 3.1 8.0 0.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) Kinesin PF00225.18 KFP07175.1 - 1.4e-93 313.2 1.7 1.4e-93 313.2 1.2 3.9 3 1 1 4 4 4 1 Kinesin motor domain Reo_sigmaC PF04582.7 KFP07175.1 - 0.011 14.9 37.4 0.039 13.1 2.0 5.1 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Fumble PF03630.9 KFP07176.1 - 1.5e-147 490.9 0.1 1.7e-147 490.7 0.1 1.0 1 0 0 1 1 1 1 Fumble Yae1_N PF09811.4 KFP07177.1 - 1.6e-16 59.5 47.3 1.5e+04 -7.8 32.8 4.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal MFS_1 PF07690.11 KFP07178.1 - 2.5e-36 125.1 35.0 3.6e-22 78.5 6.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFP07178.1 - 0.00019 21.1 7.0 0.32 10.8 0.3 4.3 4 1 1 5 5 5 2 MFS_1 like family TAP_C PF03943.8 KFP07178.1 - 0.12 11.8 0.9 0.28 10.6 0.3 1.8 2 0 0 2 2 2 0 TAP C-terminal domain Abhydrolase_1 PF00561.15 KFP07179.1 - 2.6e-25 89.3 0.2 3.2e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFP07179.1 - 2.7e-11 43.4 0.1 1.4e-10 41.0 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP07179.1 - 2.8e-11 43.7 0.0 5.1e-11 42.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 KFP07179.1 - 2.7e-05 23.4 0.0 5.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.8 KFP07179.1 - 0.0002 20.9 0.0 0.0021 17.5 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 KFP07179.1 - 0.035 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 KFP07179.1 - 0.072 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 KFP07179.1 - 0.096 12.1 0.1 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FA_hydroxylase PF04116.8 KFP07180.1 - 2.1e-14 53.8 19.5 2.1e-14 53.8 13.5 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Actin PF00022.14 KFP07181.1 - 4.1e-162 539.0 0.0 4.7e-162 538.8 0.0 1.0 1 0 0 1 1 1 1 Actin USP8_dimer PF08969.6 KFP07182.1 - 4.1e-15 55.7 0.0 5.5e-15 55.3 0.0 1.3 1 1 0 1 1 1 1 USP8 dimerisation domain TPR_8 PF13181.1 KFP07182.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydro_lipase PF04083.11 KFP07183.1 - 4.2e-22 77.2 0.1 9.5e-22 76.1 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFP07183.1 - 1.4e-16 60.7 0.0 6.5e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFP07183.1 - 7.1e-11 42.4 0.0 1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP07183.1 - 2.6e-09 36.9 0.2 9.3e-09 35.1 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_6 PF13480.1 KFP07183.1 - 0.08 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 KFP07184.1 - 9.2e-31 106.0 0.7 1.7e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07184.1 - 1.7e-30 103.2 0.0 2.7e-08 33.2 0.0 5.3 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFP07184.1 - 8.5e-27 92.5 3.2 4e-12 45.9 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP07184.1 - 2.2e-23 82.1 3.1 1.9e-07 31.3 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07184.1 - 1.9e-22 77.0 3.2 2.5e-06 27.1 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat DUF3098 PF11297.3 KFP07184.1 - 0.014 15.0 0.9 0.028 14.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) Abhydro_lipase PF04083.11 KFP07185.1 - 8e-23 79.5 0.1 1.7e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFP07185.1 - 9.6e-20 71.1 0.1 6.2e-18 65.1 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFP07185.1 - 3.4e-11 43.4 0.0 7.1e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP07185.1 - 1e-09 38.2 0.4 6.6e-09 35.6 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Imm24 PF15570.1 KFP07185.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 24 Abhydro_lipase PF04083.11 KFP07186.1 - 6.9e-22 76.5 0.2 1.6e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFP07186.1 - 8.9e-21 74.4 0.0 2e-20 73.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFP07186.1 - 5.7e-12 46.0 0.0 7.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP07186.1 - 5.3e-09 35.9 0.0 2e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family TMEM95 PF15203.1 KFP07187.1 - 0.024 14.0 0.2 0.041 13.2 0.2 1.3 1 0 0 1 1 1 0 TMEM95 family Cytochrom_B_N_2 PF13631.1 KFP07187.1 - 0.03 14.1 0.1 0.03 14.1 0.1 1.6 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB IL8 PF00048.15 KFP07188.1 - 1.8e-10 40.5 1.1 2.1e-10 40.4 0.8 1.0 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like zf-CSL PF05207.8 KFP07188.1 - 0.077 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 CSL zinc finger SNF2_N PF00176.18 KFP07189.1 - 3e-75 252.8 0.0 3e-75 252.8 0.0 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFP07189.1 - 6.5e-13 48.3 0.5 1.8e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TGF_beta PF00019.15 KFP07190.1 - 4.7e-35 120.0 0.3 8.5e-35 119.2 0.2 1.4 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP07190.1 - 4.8e-34 117.7 0.3 6.7e-34 117.2 0.2 1.2 1 0 0 1 1 1 1 TGF-beta propeptide Homeobox PF00046.24 KFP07191.1 - 3.9e-25 87.2 5.1 6.7e-25 86.4 3.5 1.4 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFP07191.1 - 2.9e-07 29.7 1.5 2.9e-07 29.7 1.0 2.3 2 0 0 2 2 2 1 OAR domain Homeobox_KN PF05920.6 KFP07191.1 - 0.024 14.3 0.5 0.097 12.3 0.0 2.1 2 0 0 2 2 2 0 Homeobox KN domain TP2 PF01254.13 KFP07191.1 - 0.036 14.3 0.8 0.036 14.3 0.6 2.2 2 0 0 2 2 2 0 Nuclear transition protein 2 V-set PF07686.12 KFP07193.1 - 9.7e-09 35.1 0.1 1.5e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP07193.1 - 7.7e-06 25.6 0.0 1.8e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP07193.1 - 3.7e-05 23.7 0.0 0.00014 21.8 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Shisa PF13908.1 KFP07193.1 - 0.03 14.4 0.2 0.043 13.9 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Beach PF02138.13 KFP07194.1 - 3.4e-105 351.3 0.2 6.5e-105 350.4 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KFP07194.1 - 5.2e-13 48.7 0.1 1.1e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KFP07194.1 - 2.8e-10 39.6 24.3 1.5e-08 34.2 0.1 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat LRR_4 PF12799.2 KFP07195.1 - 2.4e-24 84.4 33.9 6.2e-09 35.2 2.8 5.1 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP07195.1 - 6.9e-24 83.3 52.0 5.8e-09 35.5 2.4 4.1 2 1 4 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 KFP07195.1 - 1.7e-13 48.5 19.3 0.016 15.1 0.1 7.4 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 KFP07195.1 - 3.2e-11 41.5 8.5 0.085 13.0 0.2 7.6 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 KFP07195.1 - 1.1e-07 31.1 11.5 0.13 12.4 0.1 6.5 7 1 0 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.1 KFP07195.1 - 1.1 8.8 5.4 1.3 8.5 1.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeat RIX1 PF08167.7 KFP07196.1 - 0.0055 16.4 3.1 0.029 14.0 0.0 3.2 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis FmrO PF07091.6 KFP07196.1 - 0.027 13.4 0.2 0.063 12.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) RhoGAP PF00620.22 KFP07197.1 - 1.4e-48 164.3 0.0 4.2e-48 162.7 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KFP07197.1 - 0.029 14.5 0.0 0.092 12.9 0.0 1.8 1 0 0 1 1 1 0 PH domain I_LWEQ PF01608.12 KFP07197.1 - 0.11 12.3 6.6 0.15 12.0 3.8 1.8 2 0 0 2 2 2 0 I/LWEQ domain DUF4337 PF14235.1 KFP07197.1 - 0.13 12.0 2.8 0.14 11.9 1.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) APG6 PF04111.7 KFP07197.1 - 0.19 10.7 9.9 0.33 9.9 6.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFP07197.1 - 0.52 9.8 16.0 0.26 10.8 8.7 2.1 2 0 0 2 2 2 0 IncA protein Tropomyosin_1 PF12718.2 KFP07197.1 - 0.75 9.6 18.0 2.6 7.8 12.2 1.9 1 1 0 1 1 1 0 Tropomyosin like Striatin PF08232.7 KFP07197.1 - 1.1 9.5 16.7 0.057 13.7 6.6 2.3 2 1 1 3 3 3 0 Striatin family SPX PF03105.14 KFP07197.1 - 3.1 7.5 10.0 3.6 7.2 6.9 1.3 1 1 0 1 1 1 0 SPX domain V_ATPase_I PF01496.14 KFP07197.1 - 6.4 4.4 7.9 9.5 3.9 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 KFP07198.1 - 5e-66 222.4 0.0 6.3e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07198.1 - 1.2e-29 103.1 0.0 1.6e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFP07198.1 - 5.6e-07 28.8 0.1 8.7e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP07198.1 - 5.1e-05 22.3 0.1 9.1e-05 21.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFP07198.1 - 0.00034 20.0 0.2 0.00066 19.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFP07198.1 - 0.00057 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FERM_M PF00373.13 KFP07199.1 - 1.5e-26 93.0 1.8 5.1e-26 91.3 1.2 1.9 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.5 KFP07199.1 - 2e-20 72.7 2.0 3.2e-20 72.1 0.1 2.2 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFP07199.1 - 6.9e-18 64.4 2.4 8.9e-18 64.1 0.4 2.2 2 0 0 2 2 2 1 FERM N-terminal domain PDZ PF00595.19 KFP07200.1 - 4.8e-09 36.2 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP07200.1 - 5.4e-06 26.2 0.0 9.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Y_phosphatase PF00102.22 KFP07201.1 - 8.3e-71 238.0 0.0 1.1e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFP07201.1 - 0.00091 18.8 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP07201.1 - 0.00098 19.4 0.0 0.034 14.3 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP07201.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate TGF_beta PF00019.15 KFP07202.1 - 1.7e-34 118.2 0.2 3.4e-34 117.2 0.2 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP07202.1 - 9.5e-06 25.0 0.2 3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 TGF-beta propeptide TGF_beta PF00019.15 KFP07203.1 - 1.5e-36 124.8 0.5 3.2e-36 123.7 0.4 1.6 1 0 0 1 1 1 1 Transforming growth factor beta like domain TGFb_propeptide PF00688.13 KFP07203.1 - 1.6e-32 112.7 0.0 2.4e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 TGF-beta propeptide Peptidase_S41 PF03572.13 KFP07204.1 - 2.3e-127 420.8 0.0 4.9e-32 110.6 0.0 4.2 4 0 0 4 4 4 4 Peptidase family S41 DUF3436 PF11918.3 KFP07204.1 - 1.1e-21 76.7 2.7 2.2e-20 72.6 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3436) muHD PF10291.4 KFP07204.1 - 0.00077 18.7 0.0 1.2 8.2 0.0 3.6 4 0 0 4 4 4 2 Muniscin C-terminal mu homology domain zf-C2H2 PF00096.21 KFP07205.1 - 0.0028 17.9 32.3 0.094 13.0 4.1 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type SET PF00856.23 KFP07205.1 - 0.038 14.2 2.8 0.069 13.4 0.0 2.7 2 2 0 2 2 2 0 SET domain zf-C2H2_2 PF12756.2 KFP07205.1 - 0.29 11.2 17.7 9.7 6.3 0.2 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Uso1_p115_C PF04871.8 KFP07205.1 - 0.53 10.2 9.0 0.94 9.4 5.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C2H2_4 PF13894.1 KFP07205.1 - 0.55 10.6 26.6 0.2 12.0 3.8 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 KFP07205.1 - 8 6.8 18.7 0.19 11.9 0.8 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Anth_Ig PF05587.8 KFP07206.1 - 9.1e-45 150.8 1.4 1.4e-44 150.2 1.0 1.3 1 0 0 1 1 1 1 Anthrax receptor extracellular domain VWA PF00092.23 KFP07206.1 - 1.3e-16 60.8 0.0 1.8e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFP07206.1 - 8.9e-09 35.6 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFP07206.1 - 0.00021 20.5 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Ant_C PF05586.6 KFP07207.1 - 2.7e-41 139.9 1.1 3.3e-41 139.6 0.7 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region 7tm_1 PF00001.16 KFP07208.1 - 2.2e-51 174.5 27.6 2.5e-51 174.3 19.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP07208.1 - 2.2e-05 23.7 26.6 3.7e-05 23.0 18.5 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.3 KFP07208.1 - 0.68 9.4 19.6 0.015 14.8 7.5 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF4131 PF13567.1 KFP07208.1 - 3.6 6.9 7.5 1.4 8.2 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PSP94 PF05825.6 KFP07209.1 - 2e-21 76.0 10.6 2.1e-21 75.9 7.4 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) Pacifastin_I PF05375.8 KFP07209.1 - 0.03 13.8 10.8 0.03 13.8 7.5 2.1 2 2 0 2 2 2 0 Pacifastin inhibitor (LCMII) CXCXC PF03128.9 KFP07209.1 - 3.7 7.8 0.0 3.7 7.8 0.0 4.1 5 0 0 5 5 5 0 CXCXC repeat PSP94 PF05825.6 KFP07210.1 - 5e-21 74.7 5.7 5.6e-21 74.6 4.0 1.0 1 0 0 1 1 1 1 Beta-microseminoprotein (PSP-94) VWC PF00093.13 KFP07210.1 - 0.0032 17.5 6.1 0.0096 16.0 4.2 1.8 1 1 0 1 1 1 1 von Willebrand factor type C domain RINGv PF12906.2 KFP07211.1 - 1.3e-15 57.1 17.0 4.5e-15 55.4 11.8 2.0 1 0 0 1 1 1 1 RING-variant domain DctQ PF04290.7 KFP07211.1 - 0.0027 17.4 0.9 0.004 16.9 0.6 1.2 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component zf-RING_2 PF13639.1 KFP07211.1 - 0.013 15.3 16.3 0.013 15.3 11.3 2.7 3 0 0 3 3 3 0 Ring finger domain p450 PF00067.17 KFP07213.1 - 1.3e-149 498.7 0.1 1.4e-149 498.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3216 PF11505.3 KFP07213.1 - 0.044 13.5 0.0 2.2 8.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3216) Imm47 PF15586.1 KFP07213.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 47 BLOC1_2 PF10046.4 KFP07214.1 - 8.3e-30 102.8 5.5 1e-29 102.5 3.8 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ParB PF08775.5 KFP07214.1 - 0.0018 18.5 1.8 0.0029 17.9 1.3 1.3 1 0 0 1 1 1 1 ParB family DUF3782 PF12644.2 KFP07214.1 - 0.0058 16.3 0.1 0.39 10.5 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3782) NPV_P10 PF05531.7 KFP07214.1 - 0.042 14.0 0.2 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PKD_channel PF08016.7 KFP07215.1 - 6.5e-156 519.0 17.8 6.5e-156 519.0 12.4 1.4 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 KFP07215.1 - 2.2e-24 85.8 30.3 2.2e-24 85.8 21.0 1.6 2 0 0 2 2 2 1 Ion transport protein EF-hand_1 PF00036.27 KFP07215.1 - 0.0022 17.1 2.0 0.2 11.0 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KFP07215.1 - 0.0025 17.9 0.7 0.0025 17.9 0.5 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP07215.1 - 0.0028 17.3 2.1 0.46 10.5 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KFP07215.1 - 0.003 17.1 0.8 0.028 14.0 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair PDR_CDR PF06422.7 KFP07215.1 - 0.61 9.7 0.0 0.61 9.7 0.0 2.9 4 0 0 4 4 4 0 CDR ABC transporter CwfJ_C_1 PF04677.10 KFP07216.1 - 3.1e-34 117.2 0.0 5.1e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.20 KFP07217.1 - 4e-42 144.1 0.1 9.7e-42 142.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07217.1 - 2.2e-25 89.2 0.0 5.8e-25 87.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase IKKbetaNEMObind PF12179.3 KFP07217.1 - 7.8e-12 44.8 1.0 2.6e-11 43.1 0.7 2.0 1 0 0 1 1 1 1 I-kappa-kinase-beta NEMO binding domain Kdo PF06293.9 KFP07217.1 - 8.6e-05 21.6 0.0 0.00021 20.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP07217.1 - 0.0029 17.3 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP07217.1 - 0.0091 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Band_7 PF01145.20 KFP07218.1 - 8.5e-16 58.3 0.0 8.5e-16 58.3 0.0 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family Bundlin PF05307.6 KFP07218.1 - 0.012 15.4 0.1 0.032 14.1 0.0 1.8 2 0 0 2 2 2 0 Bundlin DUF4346 PF14251.1 KFP07218.1 - 0.08 12.6 2.6 0.12 12.1 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) Spc97_Spc98 PF04130.8 KFP07219.1 - 3.6e-124 415.0 13.0 3.6e-124 415.0 9.0 1.9 2 0 0 2 2 2 1 Spc97 / Spc98 family zf-C2H2_4 PF13894.1 KFP07220.1 - 0.033 14.5 0.1 0.059 13.7 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger PRAP PF15314.1 KFP07221.1 - 1e-14 54.4 6.1 1.4e-14 54.0 4.3 1.3 1 0 0 1 1 1 1 Proline-rich acidic protein 1, pregnancy-specific uterine DUF3710 PF12502.3 KFP07221.1 - 0.015 14.6 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) ECH PF00378.15 KFP07222.1 - 1.6e-65 220.6 1.0 1.8e-65 220.4 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFP07222.1 - 0.025 14.3 0.1 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 MMR_HSR1 PF01926.18 KFP07223.1 - 3.4e-13 49.5 0.0 5.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP07223.1 - 4.6e-06 25.9 0.1 5.6e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 KFP07223.1 - 0.00044 19.4 0.0 0.00066 18.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KFP07223.1 - 0.00053 19.2 0.4 0.0011 18.1 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function, DUF258 IIGP PF05049.8 KFP07223.1 - 0.0017 17.2 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 KFP07223.1 - 0.0028 17.4 1.0 0.29 10.9 0.2 2.3 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.4 KFP07223.1 - 0.0031 17.0 0.0 2.9 7.3 0.0 2.8 4 0 0 4 4 4 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFP07223.1 - 0.0032 17.4 0.0 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 KFP07223.1 - 0.019 14.3 0.1 3.3 7.0 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFP07223.1 - 0.037 14.1 0.0 0.32 11.1 0.0 2.3 2 1 1 3 3 3 0 AAA domain Miro PF08477.8 KFP07223.1 - 0.041 14.3 0.0 0.097 13.1 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 KFP07223.1 - 0.059 12.8 0.1 7.8 5.9 0.0 2.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KFP07223.1 - 0.11 12.7 0.1 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KFP07223.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin DUF815 PF05673.8 KFP07223.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Ras PF00071.17 KFP07223.1 - 0.13 11.6 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Ras family MobB PF03205.9 KFP07223.1 - 0.14 11.8 0.5 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KFP07223.1 - 0.15 11.5 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 KFP07223.1 - 0.15 10.6 0.0 0.73 8.4 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Abhydro_lipase PF04083.11 KFP07224.1 - 1.4e-18 65.9 0.0 2.9e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFP07224.1 - 1.2e-14 54.4 0.0 1e-13 51.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFP07224.1 - 1.6e-06 27.9 0.0 1.1e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP07224.1 - 4.9e-05 23.3 0.0 0.00014 21.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 KFP07224.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Amino_oxidase PF01593.19 KFP07225.1 - 3.2e-06 26.4 0.1 0.039 13.0 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase PTEN_C2 PF10409.4 KFP07227.1 - 4e-44 149.5 3.2 6.3e-44 148.9 2.2 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 KFP07227.1 - 9.4e-09 34.9 0.0 4.2e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFP07227.1 - 3.1e-05 23.4 0.0 7.6e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFP07227.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP07227.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate DUF3256 PF11644.3 KFP07227.1 - 0.02 14.3 0.3 0.052 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) AAA PF00004.24 KFP07228.1 - 7.8e-37 126.4 0.0 2.2e-36 124.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP07228.1 - 5.7e-07 29.7 0.1 0.00024 21.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFP07228.1 - 5.1e-06 26.5 0.5 0.00024 21.1 0.4 2.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFP07228.1 - 1.3e-05 24.3 0.0 4.7e-05 22.5 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFP07228.1 - 1.8e-05 25.5 0.1 4.9e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFP07228.1 - 2.9e-05 23.9 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFP07228.1 - 9e-05 22.2 0.1 0.00091 18.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KFP07228.1 - 0.00015 21.2 1.5 0.23 10.8 0.1 2.5 2 1 1 3 3 2 2 AAA domain Zeta_toxin PF06414.7 KFP07228.1 - 0.00025 20.1 0.0 0.00087 18.4 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin DEAD PF00270.24 KFP07228.1 - 0.0024 17.4 0.1 0.22 10.9 0.0 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_33 PF13671.1 KFP07228.1 - 0.0029 17.5 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFP07228.1 - 0.0035 16.5 0.0 0.035 13.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KFP07228.1 - 0.0059 16.0 0.1 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.10 KFP07228.1 - 0.007 15.0 0.2 0.018 13.7 0.1 1.9 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_2 PF07724.9 KFP07228.1 - 0.0077 16.1 0.0 0.032 14.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KFP07228.1 - 0.0082 16.4 0.2 0.043 14.1 0.0 2.3 3 0 0 3 3 2 1 AAA domain SKI PF01202.17 KFP07228.1 - 0.01 15.6 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.17 KFP07228.1 - 0.021 14.9 0.0 0.046 13.9 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KFP07228.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 KFP07228.1 - 0.029 14.4 0.3 0.22 11.5 0.0 2.7 3 1 0 3 3 2 0 Sigma-54 interaction domain TIP49 PF06068.8 KFP07228.1 - 0.03 13.0 0.0 0.066 11.9 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 KFP07228.1 - 0.036 13.2 0.1 0.46 9.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 KFP07228.1 - 0.037 14.0 1.3 0.94 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 KFP07228.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFP07228.1 - 0.11 11.6 0.3 0.7 8.9 0.0 2.4 2 1 1 3 3 3 0 KaiC AAA_10 PF12846.2 KFP07228.1 - 0.12 11.8 0.2 7.2 5.9 0.0 2.8 2 1 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 KFP07228.1 - 0.21 11.5 0.3 3.1 7.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 KFP07228.1 - 0.27 11.5 1.1 1.1 9.5 0.0 2.5 3 2 0 3 3 3 0 ABC transporter APS_kinase PF01583.15 KFP07229.1 - 2.3e-73 245.0 0.0 3.7e-73 244.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 KFP07229.1 - 1.2e-66 224.1 0.0 1.8e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 KFP07229.1 - 3.6e-51 172.7 0.0 7.1e-51 171.7 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KFP07229.1 - 2.5e-07 30.6 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFP07229.1 - 2.2e-05 25.2 0.0 6.8e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFP07229.1 - 3.3e-05 24.1 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhdYeFM_antitox PF02604.14 KFP07229.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system KTI12 PF08433.5 KFP07229.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 KFP07229.1 - 0.17 11.4 0.0 0.44 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain His_Phos_2 PF00328.17 KFP07230.1 - 8e-21 74.7 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PAP2_C PF14360.1 KFP07231.1 - 1.4e-30 105.3 14.4 1.4e-30 105.3 10.0 2.4 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 KFP07231.1 - 4.9e-06 26.2 9.3 4.9e-06 26.2 6.5 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KFP07231.1 - 5.6e-05 22.7 6.2 5.6e-05 22.7 4.3 1.8 1 1 1 2 2 2 1 PAP2 superfamily SAM_1 PF00536.25 KFP07231.1 - 0.00024 21.2 0.0 0.00063 19.8 0.0 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP07231.1 - 0.031 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFP07231.1 - 0.084 12.6 0.2 0.084 12.6 0.1 2.9 3 1 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain RRM_1 PF00076.17 KFP07232.1 - 1.2e-40 137.0 1.4 3.7e-17 61.6 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07232.1 - 4.2e-32 109.9 0.4 1.6e-10 40.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.1 KFP07232.1 - 7.8e-30 103.0 0.1 1.9e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_5 PF13893.1 KFP07232.1 - 6.7e-23 80.3 0.4 2e-08 33.9 0.2 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFP07232.1 - 0.00056 19.5 0.1 0.22 11.2 0.0 2.6 3 0 0 3 3 3 2 Limkain b1 dsrm PF00035.20 KFP07232.1 - 0.14 12.7 0.8 6.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Double-stranded RNA binding motif Spc42p PF11544.3 KFP07233.1 - 0.13 12.2 1.8 0.3 11.0 1.3 1.5 1 0 0 1 1 1 0 Spindle pole body component Spc42p Med4 PF10018.4 KFP07233.1 - 0.13 11.6 1.0 0.18 11.1 0.6 1.4 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF641 PF04859.7 KFP07233.1 - 0.14 11.8 2.9 0.11 12.2 0.5 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4279 PF14106.1 KFP07233.1 - 0.16 11.8 0.4 0.35 10.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) TMF_DNA_bd PF12329.3 KFP07233.1 - 0.21 11.4 5.5 0.33 10.8 0.9 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Rabaptin PF03528.10 KFP07233.1 - 0.23 11.3 3.3 8.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Rabaptin Med9 PF07544.8 KFP07233.1 - 0.5 10.1 3.4 0.63 9.8 1.5 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 KFP07233.1 - 1.1 8.8 5.2 1.4 8.4 3.6 1.4 1 1 0 1 1 1 0 IncA protein Pkinase PF00069.20 KFP07234.1 - 5.9e-69 232.0 0.0 8.1e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07234.1 - 4e-36 124.4 0.0 6.2e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 KFP07234.1 - 1.6e-35 120.7 0.1 2.2e-21 75.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.1 KFP07234.1 - 1.5e-05 24.1 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFP07234.1 - 0.0095 15.6 0.0 0.36 10.5 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 KFP07234.1 - 0.045 14.2 4.0 0.16 12.5 2.8 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Cadherin PF00028.12 KFP07236.1 - 3.3e-17 62.5 0.0 6.2e-11 42.4 0.0 2.3 2 1 0 2 2 2 2 Cadherin domain Sema PF01403.14 KFP07237.1 - 9.1e-125 416.5 0.0 1e-124 416.3 0.0 1.0 1 0 0 1 1 1 1 Sema domain PQQ_3 PF13570.1 KFP07237.1 - 0.015 15.5 0.5 22 5.4 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain Iso_dh PF00180.15 KFP07238.1 - 2e-57 194.7 0.0 7.6e-50 169.8 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Peptidase_M1 PF01433.15 KFP07239.1 - 3.4e-43 148.2 0.0 3.8e-26 92.1 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M1 EMP24_GP25L PF01105.19 KFP07240.1 - 5.3e-29 101.2 0.0 5.8e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GOLD_2 PF13897.1 KFP07240.1 - 0.038 14.2 0.1 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Ank_2 PF12796.2 KFP07241.1 - 8.7e-36 122.1 6.0 4.3e-18 65.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07241.1 - 2.4e-18 64.9 3.6 1.1e-06 28.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFP07241.1 - 3.7e-15 55.9 0.9 4e-05 24.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP07241.1 - 1.1e-12 47.7 2.7 9.6e-08 32.0 0.1 3.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07241.1 - 1.3e-12 46.6 0.9 0.00053 19.9 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat FMN_dh PF01070.13 KFP07241.1 - 0.0065 15.3 0.0 0.0089 14.9 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NAD_binding_10 PF13460.1 KFP07241.1 - 0.033 14.2 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Hydrolase PF00702.21 KFP07241.1 - 0.1 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RasGEF PF00617.14 KFP07242.1 - 6.9e-59 198.7 0.5 2e-58 197.2 0.4 1.8 1 0 0 1 1 1 1 RasGEF domain RhoGEF PF00621.15 KFP07242.1 - 3.7e-34 118.1 0.8 3.7e-34 118.1 0.6 2.2 3 0 0 3 3 3 1 RhoGEF domain RasGEF_N PF00618.15 KFP07242.1 - 3.8e-23 81.5 2.5 1.1e-16 60.8 0.1 3.9 4 0 0 4 4 4 2 RasGEF N-terminal motif PH PF00169.24 KFP07242.1 - 7.4e-18 64.6 0.9 9.3e-17 61.1 0.1 2.8 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 KFP07242.1 - 0.00082 19.6 0.2 0.0061 16.7 0.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain IQ PF00612.22 KFP07242.1 - 0.0065 16.0 1.4 0.018 14.6 1.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif HR1 PF02185.11 KFP07242.1 - 5.7 6.7 12.3 1.9 8.2 2.0 3.2 3 0 0 3 3 3 0 Hr1 repeat Peptidase_C1 PF00112.18 KFP07243.1 - 6.1e-75 251.8 0.4 6.9e-75 251.6 0.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 KFP07243.1 - 4.8e-05 22.0 0.8 0.0073 14.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family WD40 PF00400.27 KFP07244.1 - 9.8e-10 37.9 7.3 3.5e-05 23.5 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat gpW PF02831.10 KFP07244.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 gpW FERM_M PF00373.13 KFP07245.1 - 3.1e-22 79.0 0.0 5.4e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 KFP07245.1 - 7.9e-17 61.0 0.2 1.6e-15 56.9 0.1 2.5 2 0 0 2 2 2 1 FERM N-terminal domain FA PF08736.6 KFP07245.1 - 2.4e-16 59.2 0.3 6.8e-16 57.7 0.2 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_C PF09380.5 KFP07245.1 - 1.2e-14 54.2 0.3 2.3e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain YcxB PF14317.1 KFP07245.1 - 0.0015 17.7 0.2 0.0031 16.7 0.1 1.5 1 0 0 1 1 1 1 YcxB-like protein Cbl_N PF02262.11 KFP07247.1 - 0.0097 15.6 3.1 0.033 13.9 0.4 2.2 1 1 1 2 2 2 1 CBL proto-oncogene N-terminal domain 1 Atg14 PF10186.4 KFP07247.1 - 0.56 9.1 28.0 2.2 7.1 9.7 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 NIF PF03031.13 KFP07248.1 - 2.8e-54 183.0 1.1 2.8e-54 183.0 0.8 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase eIF3_subunit PF08597.5 KFP07249.1 - 8.5e-61 205.6 25.8 9.5e-61 205.4 17.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit BRICHOS PF04089.9 KFP07249.1 - 0.18 11.6 0.1 0.18 11.6 0.0 2.4 1 1 2 3 3 3 0 BRICHOS domain Gag_p17 PF00540.13 KFP07249.1 - 1.1 9.0 6.4 6.6 6.5 0.0 2.2 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) MscL PF01741.13 KFP07249.1 - 1.7 8.8 8.0 15 5.7 0.0 2.5 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL YjgP_YjgQ PF03739.9 KFP07249.1 - 2.3 6.8 3.8 3.9 6.1 2.6 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF59 PF01883.14 KFP07250.1 - 1.9e-05 24.5 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 ADAM_spacer1 PF05986.9 KFP07251.1 - 5.1e-33 113.3 0.0 9.8e-33 112.4 0.0 1.5 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Reprolysin PF01421.14 KFP07251.1 - 1.8e-29 102.7 0.0 4.2e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.14 KFP07251.1 - 2.9e-26 91.3 140.3 1.5e-08 34.6 4.9 10.8 12 0 0 12 12 12 8 Thrombospondin type 1 domain Pep_M12B_propep PF01562.14 KFP07251.1 - 2.3e-21 75.9 0.0 4.8e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 KFP07251.1 - 3.3e-14 53.2 1.1 4.5e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFP07251.1 - 1.5e-10 41.6 0.1 3.6e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP07251.1 - 5e-10 39.7 1.5 7.6e-10 39.1 0.0 2.1 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFP07251.1 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFP07251.1 - 0.08 12.6 0.2 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Matrixin SAM_decarbox PF01536.11 KFP07251.1 - 1.3 7.6 4.2 0.55 8.8 0.3 1.9 2 0 0 2 2 2 0 Adenosylmethionine decarboxylase MRG PF05712.8 KFP07252.1 - 1.4e-56 190.5 0.2 2.2e-56 189.8 0.1 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KFP07252.1 - 3.8e-10 39.3 1.0 2.1e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Neur_chan_memb PF02932.11 KFP07252.1 - 0.25 11.1 1.0 0.34 10.7 0.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ank_2 PF12796.2 KFP07253.1 - 6.1e-42 141.8 7.2 7.6e-16 58.2 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07253.1 - 3.8e-36 121.1 3.8 1e-07 31.3 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFP07253.1 - 2.8e-31 107.2 1.1 9.7e-10 38.6 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP07253.1 - 6e-31 105.7 5.7 3.7e-08 33.3 0.1 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07253.1 - 4.1e-25 85.3 0.4 0.00016 21.5 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Seryl_tRNA_N PF02403.17 KFP07253.1 - 0.00041 20.3 9.0 0.00041 20.3 6.3 13.1 2 1 13 15 15 15 1 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 KFP07253.1 - 0.00048 18.7 146.9 0.03 12.7 10.7 7.8 2 1 6 8 8 8 5 AAA domain Filament PF00038.16 KFP07253.1 - 0.00055 19.4 170.7 0.0043 16.5 33.8 8.4 2 1 5 7 7 7 5 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFP07253.1 - 0.0023 17.6 12.7 0.0023 17.6 8.8 11.0 4 3 5 10 10 9 2 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 KFP07253.1 - 0.0051 16.7 2.0 0.0051 16.7 1.4 10.1 10 3 1 11 11 11 2 Proteins of 100 residues with WXG DUF2681 PF10883.3 KFP07253.1 - 0.0089 16.2 5.3 0.0089 16.2 3.6 12.0 8 5 4 13 13 12 1 Protein of unknown function (DUF2681) Myosin_tail_1 PF01576.14 KFP07253.1 - 0.032 11.9 190.1 0.0067 14.2 23.1 7.9 2 1 3 7 7 7 0 Myosin tail Reo_sigmaC PF04582.7 KFP07253.1 - 0.048 12.8 49.7 0.012 14.8 1.0 7.8 4 2 5 10 10 10 0 Reovirus sigma C capsid protein TLE_N PF03920.10 KFP07254.1 - 4e-52 175.6 7.7 6e-52 175.0 5.3 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.27 KFP07254.1 - 3.9e-30 102.6 23.0 1.6e-08 34.1 0.4 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFP07254.1 - 0.053 11.8 0.0 1.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Pox_A8 PF04745.7 KFP07254.1 - 0.16 10.8 0.1 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 VITF-3 subunit protein Ribosomal_S18 PF01084.15 KFP07254.1 - 0.25 11.2 0.5 0.45 10.4 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S18 Kinesin PF00225.18 KFP07255.1 - 3.4e-101 338.2 1.7 4.2e-101 338.0 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain ADIP PF11559.3 KFP07255.1 - 0.11 12.4 18.7 0.1 12.5 11.3 2.2 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tnp_P_element PF12017.3 KFP07255.1 - 0.22 10.7 5.5 0.26 10.5 2.7 1.9 1 1 1 2 2 2 0 Transposase protein IncA PF04156.9 KFP07255.1 - 0.24 10.9 18.7 0.51 9.8 13.0 1.6 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KFP07255.1 - 0.92 9.3 27.1 0.029 14.1 13.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 KFP07255.1 - 1.5 8.7 13.5 1.6 8.7 8.4 1.7 1 1 0 1 1 1 0 FlxA-like protein XhlA PF10779.4 KFP07255.1 - 2.9 7.8 10.5 0.86 9.5 4.6 2.2 1 1 0 2 2 2 0 Haemolysin XhlA AAA_23 PF13476.1 KFP07255.1 - 5 7.3 22.2 0.11 12.8 7.6 3.2 3 0 0 3 3 3 0 AAA domain HlyIII PF03006.15 KFP07256.1 - 1.1e-27 96.8 15.3 1.7e-27 96.2 10.6 1.2 1 0 0 1 1 1 1 Haemolysin-III related C5-epim_C PF06662.8 KFP07258.1 - 2.4e-76 255.2 0.1 4.1e-76 254.5 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus EspG PF06872.6 KFP07258.1 - 0.21 9.9 0.0 1.2 7.4 0.0 1.9 2 0 0 2 2 2 0 EspG protein NAD_binding_6 PF08030.7 KFP07259.1 - 5.1e-29 101.2 0.0 7.7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFP07259.1 - 3.4e-22 78.2 0.0 5.8e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFP07259.1 - 1.2e-17 64.1 1.9 2.3e-17 63.2 1.3 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_6 PF13405.1 KFP07259.1 - 7.9e-12 44.0 0.1 0.0023 17.6 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 KFP07259.1 - 5.1e-11 41.0 0.0 0.00023 20.2 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFP07259.1 - 1.2e-10 41.3 0.0 0.00019 21.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP07259.1 - 8.5e-09 34.3 1.0 5e-05 22.4 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFP07259.1 - 2.9e-05 23.5 0.0 0.084 12.5 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair NAD_binding_1 PF00175.16 KFP07259.1 - 0.0042 17.6 0.0 0.16 12.5 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFP07259.1 - 0.005 16.9 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain LRR_8 PF13855.1 KFP07260.1 - 5e-13 48.5 15.1 1.4e-08 34.3 3.7 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 KFP07260.1 - 1.4e-12 46.9 19.2 9.1e-09 34.7 5.5 3.3 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KFP07260.1 - 4.6e-12 45.8 0.3 6.4e-12 45.3 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 KFP07260.1 - 4.6e-07 29.2 13.0 0.00036 20.2 0.2 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 KFP07260.1 - 8.7e-07 28.1 12.9 0.039 14.1 0.2 4.9 5 0 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 KFP07260.1 - 3.3e-06 26.3 9.3 0.016 15.1 0.1 4.3 4 1 0 4 4 4 3 Leucine Rich Repeat BUD22 PF09073.5 KFP07260.1 - 0.0012 18.0 19.6 0.0012 17.9 13.6 1.1 1 0 0 1 1 1 1 BUD22 LRR_2 PF07723.8 KFP07260.1 - 0.24 11.9 2.2 17 6.0 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Nop14 PF04147.7 KFP07260.1 - 0.6 7.9 38.5 0.68 7.7 26.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFP07260.1 - 7.7 4.4 25.9 11 3.9 17.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Integrin_alpha2 PF08441.7 KFP07261.1 - 2.8e-83 280.2 1.4 4.3e-83 279.6 0.9 1.2 1 0 0 1 1 1 1 Integrin alpha VWA PF00092.23 KFP07261.1 - 1.8e-39 135.2 0.1 3.1e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FG-GAP PF01839.18 KFP07261.1 - 7.2e-14 50.9 2.9 0.00038 20.0 0.0 3.7 3 0 0 3 3 3 3 FG-GAP repeat VWA_2 PF13519.1 KFP07261.1 - 2.6e-12 47.1 0.0 4.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VCBS PF13517.1 KFP07261.1 - 2.4e-06 27.8 1.5 0.0015 18.8 0.0 3.0 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 KFP07261.1 - 0.00069 19.5 13.1 0.27 11.2 0.1 5.3 6 0 0 6 6 6 2 FG-GAP repeat vWA-TerF-like PF10138.4 KFP07261.1 - 0.039 13.7 0.1 0.097 12.4 0.1 1.6 1 0 0 1 1 1 0 vWA found in TerF C terminus Cytochrom_B_N_2 PF13631.1 KFP07262.1 - 4.2e-07 29.9 0.0 4.2e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ank PF00023.25 KFP07263.1 - 6e-49 161.5 15.4 1.3e-09 37.3 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_2 PF12796.2 KFP07263.1 - 1.2e-46 156.9 10.9 2.3e-19 69.5 1.5 5.7 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP07263.1 - 3.6e-36 122.8 6.9 4.3e-13 49.3 0.1 6.7 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07263.1 - 2e-32 107.9 14.6 1.4e-07 31.0 0.0 9.0 8 1 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KFP07263.1 - 2.3e-31 107.1 15.2 3.9e-09 36.4 0.5 8.0 3 2 4 7 7 7 6 Ankyrin repeats (many copies) CLN6 PF15156.1 KFP07264.1 - 2.9e-151 502.3 18.6 3.3e-151 502.1 12.9 1.0 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 Zn_dep_PLPC PF00882.13 KFP07264.1 - 0.0087 15.7 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C DUF3397 PF11877.3 KFP07264.1 - 0.04 13.9 0.1 0.04 13.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) Herpes_LMP1 PF05297.6 KFP07264.1 - 0.17 10.8 8.2 0.036 13.0 3.4 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3959 PF13105.1 KFP07264.1 - 0.2 10.9 4.0 0.3 10.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) EF-hand_7 PF13499.1 KFP07266.1 - 1.6e-13 50.6 0.0 6.7e-08 32.5 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP07266.1 - 1.3e-10 40.2 0.1 4e-05 23.1 0.0 3.9 2 1 2 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFP07266.1 - 1.5e-10 40.4 0.4 2.9e-06 26.7 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP07266.1 - 2.8e-10 38.7 1.3 0.00058 18.9 0.1 4.1 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.1 KFP07266.1 - 6.2e-10 38.8 0.0 0.0003 20.6 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 KFP07266.1 - 0.0096 15.5 0.8 0.34 10.5 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) PINIT PF14324.1 KFP07267.1 - 8.3e-46 155.6 0.2 1.8e-45 154.5 0.1 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFP07267.1 - 4.3e-20 70.9 5.2 8.5e-20 70.0 3.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFP07267.1 - 0.00087 18.7 1.7 0.0023 17.3 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KFP07267.1 - 0.0095 15.4 0.2 0.024 14.1 0.1 1.8 1 0 0 1 1 1 1 SAP domain Peptidase_M42 PF05343.9 KFP07267.1 - 0.21 10.3 0.1 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase zf-C3HC4 PF00097.20 KFP07267.1 - 0.57 9.8 4.9 2.1 8.0 3.4 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KFP07267.1 - 5.4 6.7 8.5 0.29 10.8 1.7 2.1 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.20 KFP07268.1 - 3.2e-59 200.2 0.0 4.1e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07268.1 - 2.7e-38 131.5 0.0 3.6e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 KFP07268.1 - 4.1e-12 45.6 0.0 8.8e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.1 KFP07268.1 - 3.6e-06 26.1 0.0 1.1e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KFP07268.1 - 0.089 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KFP07268.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4528 PF15031.1 KFP07269.1 - 1.3e-60 202.7 0.0 1.5e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4528) Adaptin_binding PF10199.4 KFP07270.1 - 4.3e-24 85.3 3.2 5.7e-24 84.9 2.2 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.17 KFP07270.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Ras family MH2 PF03166.9 KFP07271.1 - 1.9e-77 259.2 0.0 2.6e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFP07271.1 - 3.6e-44 148.9 3.1 7.9e-44 147.8 2.1 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFP07271.1 - 7.4e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Interferon-regulatory factor 3 MH2 PF03166.9 KFP07272.1 - 6.8e-58 195.4 0.0 7.6e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.4 KFP07272.1 - 0.022 14.3 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 AbiH PF14253.1 KFP07273.1 - 0.045 13.3 0.1 0.062 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF1409 PF07197.7 KFP07274.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) DUF2369 PF10179.4 KFP07276.1 - 9e-67 225.2 6.2 2e-61 207.7 2.1 2.2 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.16 KFP07276.1 - 1.3e-08 34.8 1.9 0.0043 17.1 0.1 4.5 5 0 0 5 5 5 3 Fibronectin type III domain Arc_PepC PF06819.6 KFP07276.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Alpha-amylase_N PF02903.9 KFP07276.1 - 0.041 13.8 0.3 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Alpha amylase, N-terminal ig-like domain KH_1 PF00013.24 KFP07277.1 - 1.6e-34 117.3 5.7 8.7e-14 50.9 0.2 5.4 5 0 0 5 5 5 3 KH domain KH_3 PF13014.1 KFP07277.1 - 1.8e-25 88.1 8.4 6.1e-11 41.7 0.2 5.6 6 0 0 6 6 6 2 KH domain SAM_1 PF00536.25 KFP07277.1 - 3e-14 52.9 0.1 6.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP07277.1 - 5.8e-12 45.2 0.1 1.4e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SLS PF14611.1 KFP07277.1 - 2.5e-07 30.3 0.4 0.047 13.1 0.3 3.9 1 1 1 3 3 3 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KFP07277.1 - 0.0015 18.0 0.8 0.27 10.8 0.1 2.8 3 0 0 3 3 3 1 KH domain KH_4 PF13083.1 KFP07277.1 - 0.085 12.5 0.3 0.24 11.0 0.2 1.8 1 0 0 1 1 1 0 KH domain fn3 PF00041.16 KFP07278.1 - 1.5e-07 31.4 0.3 3.7e-07 30.1 0.0 1.8 2 1 0 2 2 2 1 Fibronectin type III domain DUF918 PF06033.6 KFP07278.1 - 0.034 13.6 0.6 0.11 11.9 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Drc1-Sld2 PF11719.3 KFP07279.1 - 0.044 12.8 19.9 0.023 13.8 1.4 3.2 2 1 1 3 3 3 0 DNA replication and checkpoint protein PilO PF04350.8 KFP07279.1 - 0.075 12.9 0.3 0.075 12.9 0.2 2.3 3 0 0 3 3 3 0 Pilus assembly protein, PilO RhoGAP PF00620.22 KFP07280.1 - 3.7e-40 137.0 0.2 4.4e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain DAG_kinase_N PF14513.1 KFP07280.1 - 0.092 12.9 0.1 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus MFS_1 PF07690.11 KFP07281.1 - 2.2e-33 115.4 20.4 2.3e-20 72.6 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2046 PF09755.4 KFP07282.1 - 5.3e-135 449.2 46.3 6.2e-135 449.0 32.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) SLAM PF06214.6 KFP07282.1 - 0.11 12.4 2.0 1.8 8.5 0.2 2.4 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein Death PF00531.17 KFP07283.1 - 4.4e-20 71.2 0.0 8.5e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 Death domain Ank PF00023.25 KFP07284.1 - 1.5e-197 630.4 70.6 1.2e-09 37.4 0.0 23.7 23 1 1 24 24 24 22 Ankyrin repeat Ank_2 PF12796.2 KFP07284.1 - 1.7e-194 630.8 83.8 3.6e-23 81.6 1.1 11.2 1 1 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFP07284.1 - 2.1e-124 392.7 40.9 3.6e-06 26.6 0.0 23.8 24 0 0 24 24 24 22 Ankyrin repeat Ank_4 PF13637.1 KFP07284.1 - 5.3e-124 402.6 43.0 1.1e-10 41.7 0.2 16.4 6 4 12 18 18 18 18 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP07284.1 - 5e-120 388.8 45.2 1.3e-10 41.1 0.0 17.1 3 3 17 20 20 20 19 Ankyrin repeats (many copies) ZU5 PF00791.15 KFP07284.1 - 1.7e-40 136.8 3.0 7.8e-38 128.3 0.1 2.9 2 0 0 2 2 2 2 ZU5 domain Asp_protease_2 PF13650.1 KFP07284.1 - 0.049 14.1 0.0 2.1 8.8 0.0 3.2 2 0 0 2 2 2 0 Aspartyl protease BTB PF00651.26 KFP07285.1 - 2e-28 98.6 5.0 1.1e-16 60.7 0.0 3.8 4 0 0 4 4 4 3 BTB/POZ domain Ras PF00071.17 KFP07285.1 - 8.7e-24 83.7 0.0 1.9e-23 82.6 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFP07285.1 - 8.7e-13 48.8 0.0 3e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein BACK PF07707.10 KFP07285.1 - 0.42 10.4 4.2 1.1 9.1 0.2 3.2 3 1 1 4 4 4 0 BTB And C-terminal Kelch Tmem26 PF09772.4 KFP07286.1 - 1.3e-104 349.3 11.1 1.5e-104 349.1 7.7 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 CLAMP PF14769.1 KFP07287.1 - 1.3e-19 70.2 0.0 1.8e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Spore_III_AB PF09548.5 KFP07287.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ARID PF01388.16 KFP07288.1 - 7.1e-20 70.6 0.0 1.7e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Anillin PF08174.6 KFP07289.1 - 4.5e-28 98.0 0.1 1.1e-27 96.7 0.1 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KFP07289.1 - 1.6e-09 37.9 0.1 6.2e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFP07289.1 - 0.00022 21.4 0.0 0.00064 19.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain HR1 PF02185.11 KFP07289.1 - 0.00068 19.3 1.5 0.0014 18.2 0.3 2.1 2 0 0 2 2 2 1 Hr1 repeat UvrD_C PF13361.1 KFP07290.1 - 0.0028 17.1 7.0 0.0043 16.5 4.9 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MCP_N PF05581.7 KFP07290.1 - 0.015 15.4 0.3 0.039 14.0 0.1 1.7 1 1 0 1 1 1 0 Vibrio chemotaxis protein N terminus Tropomyosin PF00261.15 KFP07290.1 - 0.055 12.5 20.5 0.087 11.8 14.2 1.2 1 0 0 1 1 1 0 Tropomyosin ERM PF00769.14 KFP07290.1 - 0.16 11.4 16.2 0.24 10.8 11.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Sugarporin_N PF11471.3 KFP07290.1 - 0.17 11.5 0.3 0.17 11.5 0.2 3.7 4 0 0 4 4 3 0 Maltoporin periplasmic N-terminal extension FliD_C PF07195.7 KFP07290.1 - 0.25 10.6 2.8 0.62 9.3 1.9 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FUSC PF04632.7 KFP07290.1 - 0.46 8.8 5.0 0.58 8.5 3.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family RBD-FIP PF09457.5 KFP07290.1 - 0.48 10.2 0.1 0.48 10.2 0.1 3.7 3 1 1 4 4 4 0 FIP domain DUF4094 PF13334.1 KFP07290.1 - 0.6 10.5 5.4 7.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF342 PF03961.8 KFP07290.1 - 0.67 8.3 10.7 0.49 8.7 6.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) ATP-synt_E_2 PF08112.6 KFP07290.1 - 0.79 9.8 4.8 6.7 6.8 0.2 2.9 2 1 0 2 2 2 0 ATP synthase epsilon subunit Exonuc_VII_L PF02601.10 KFP07290.1 - 0.81 8.8 15.0 2.4 7.2 10.4 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Amidase PF01425.16 KFP07290.1 - 1.4 7.6 4.0 1.9 7.2 2.8 1.1 1 0 0 1 1 1 0 Amidase COG2 PF06148.6 KFP07290.1 - 2.1 8.2 9.8 1.6 8.6 2.4 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC-like PF12805.2 KFP07290.1 - 2.2 7.1 7.4 0.38 9.6 1.9 1.8 1 1 0 2 2 2 0 FUSC-like inner membrane protein yccS APG6 PF04111.7 KFP07290.1 - 2.7 6.9 18.5 4.1 6.3 6.7 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Cache_2 PF08269.6 KFP07290.1 - 3.5 7.6 8.6 9.5 6.2 2.0 3.0 2 1 0 2 2 2 0 Cache domain UPF0449 PF15136.1 KFP07290.1 - 4.8 7.4 9.5 8.1 6.7 2.3 3.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Mit_KHE1 PF10173.4 KFP07290.1 - 7.1 6.4 7.7 15 5.3 2.3 2.6 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF904 PF06005.7 KFP07290.1 - 8 6.8 18.7 0.53 10.6 4.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 KFP07290.1 - 9.3 6.6 12.5 7.9 6.8 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1875 PF08961.5 KFP07291.1 - 2.4e-127 423.2 12.0 2.8e-127 423.0 8.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) MIT PF04212.13 KFP07291.1 - 4.3e-05 23.3 0.9 0.00011 21.9 0.6 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DivIC PF04977.10 KFP07291.1 - 0.00044 19.6 2.2 0.00044 19.6 1.5 2.0 2 1 0 2 2 2 1 Septum formation initiator HALZ PF02183.13 KFP07291.1 - 0.0012 18.5 2.7 0.0012 18.5 1.9 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF972 PF06156.8 KFP07291.1 - 0.0044 17.3 0.8 0.0044 17.3 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF972) TPR_11 PF13414.1 KFP07291.1 - 0.0054 16.3 0.5 0.011 15.3 0.4 1.5 1 0 0 1 1 1 1 TPR repeat DUF904 PF06005.7 KFP07291.1 - 0.0096 16.1 2.0 0.0096 16.1 1.4 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF904) TPR_2 PF07719.12 KFP07291.1 - 0.12 12.3 2.6 0.12 12.3 0.7 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF724 PF05266.9 KFP07291.1 - 3.1 7.3 13.7 0.15 11.7 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) JmjC PF02373.17 KFP07292.1 - 2.1e-11 44.0 0.0 1.3e-10 41.5 0.0 2.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C3HC4_2 PF13923.1 KFP07292.1 - 2 8.4 6.5 5.8 7.0 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_3 PF07649.7 KFP07292.1 - 9.7 6.3 8.3 20 5.2 5.8 1.5 1 0 0 1 1 1 0 C1-like domain TB2_DP1_HVA22 PF03134.14 KFP07293.1 - 7.9e-31 105.6 10.8 1.3e-30 105.0 7.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Sugar_tr PF00083.19 KFP07294.1 - 5.9e-33 114.1 15.6 7.2e-33 113.8 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP07294.1 - 1.2e-28 99.8 33.3 9.6e-21 73.8 9.9 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily G2F PF07474.7 KFP07296.1 - 9.5e-65 217.5 0.0 1.5e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 G2F domain Ldl_recept_b PF00058.12 KFP07296.1 - 1.3e-34 118.1 0.5 1.9e-13 50.4 0.0 5.1 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B NIDO PF06119.9 KFP07296.1 - 1.2e-27 96.4 0.0 3.1e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 Nidogen-like EGF_3 PF12947.2 KFP07296.1 - 1.9e-22 78.9 77.6 1.7e-09 37.4 6.0 5.4 5 0 0 5 5 5 5 EGF domain EGF_CA PF07645.10 KFP07296.1 - 7.9e-18 64.1 68.5 3.4e-09 36.5 5.1 5.4 5 0 0 5 5 4 4 Calcium-binding EGF domain cEGF PF12662.2 KFP07296.1 - 1.7e-14 53.1 50.9 9e-06 25.2 4.1 5.2 5 0 0 5 5 4 4 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KFP07296.1 - 5.2e-06 26.4 9.7 5.2e-06 26.4 6.7 5.5 5 0 0 5 5 4 2 Coagulation Factor Xa inhibitory site SGL PF08450.7 KFP07296.1 - 5e-05 22.7 0.1 0.0048 16.3 0.0 3.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region hEGF PF12661.2 KFP07296.1 - 0.00052 19.9 25.5 0.01 15.8 0.7 6.0 5 0 0 5 5 5 2 Human growth factor-like EGF EGF PF00008.22 KFP07296.1 - 0.0052 16.7 71.7 0.0058 16.5 6.9 5.7 5 0 0 5 5 5 4 EGF-like domain EGF_MSP1_1 PF12946.2 KFP07296.1 - 8 6.3 47.6 3.1 7.6 0.1 5.4 5 0 0 5 5 5 0 MSP1 EGF domain 1 RLL PF10036.4 KFP07297.1 - 3.9e-88 295.0 0.8 4.4e-88 294.8 0.5 1.0 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein G-gamma PF00631.17 KFP07298.1 - 9.3e-21 73.3 0.0 1e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain FERM_C PF09380.5 KFP07299.1 - 3.5e-15 55.9 0.0 9.3e-15 54.6 0.0 1.8 1 1 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.5 KFP07299.1 - 4.1e-15 55.5 0.1 1.1e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain FERM_M PF00373.13 KFP07299.1 - 2.2e-14 53.7 0.4 2.2e-14 53.7 0.3 2.0 2 1 0 2 2 2 1 FERM central domain FAM176 PF14851.1 KFP07300.1 - 0.00032 20.4 0.0 0.00045 19.9 0.0 1.1 1 0 0 1 1 1 1 FAM176 family Thioredoxin PF00085.15 KFP07300.1 - 0.0052 16.4 0.0 0.047 13.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin PROL5-SMR PF15621.1 KFP07300.1 - 0.19 12.1 0.9 0.28 11.6 0.0 1.6 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family EBV-NA3 PF05009.7 KFP07300.1 - 0.66 9.1 3.2 1.1 8.5 2.2 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SPRY PF00622.23 KFP07301.1 - 1.5e-11 44.4 0.0 3e-09 37.0 0.0 2.6 1 1 0 1 1 1 1 SPRY domain fn3 PF00041.16 KFP07301.1 - 7.8e-10 38.7 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PRY PF13765.1 KFP07301.1 - 0.0022 17.5 0.0 0.0061 16.0 0.0 1.8 1 1 1 2 2 2 1 SPRY-associated domain ATP-synt_E_2 PF08112.6 KFP07301.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase epsilon subunit DUF4200 PF13863.1 KFP07301.1 - 0.35 10.8 3.1 0.5 10.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.4 KFP07301.1 - 0.35 11.0 2.1 15 5.8 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.1 KFP07301.1 - 0.51 9.9 3.9 0.97 9.0 2.7 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Phosphorylase PF00343.15 KFP07302.1 - 0 1218.7 0.9 0 1218.5 0.6 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Abhydrolase_6 PF12697.2 KFP07303.1 - 8e-21 74.9 0.2 1.5e-20 74.0 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP07303.1 - 1.5e-20 73.3 0.2 4.7e-20 71.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP07303.1 - 1.5e-08 34.5 0.0 1.8e-06 27.6 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFP07303.1 - 1.6e-07 31.1 0.0 2.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFP07303.1 - 1.9e-07 30.7 0.1 0.011 15.2 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KFP07303.1 - 0.00075 18.7 0.2 0.0027 16.9 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.15 KFP07303.1 - 0.0012 19.0 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KFP07303.1 - 0.0019 18.0 0.2 0.0034 17.2 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF2424 PF10340.4 KFP07303.1 - 0.0035 16.0 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_4 PF08386.5 KFP07303.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Cutinase PF01083.17 KFP07303.1 - 0.021 14.5 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 KFP07303.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LIP PF03583.9 KFP07303.1 - 0.036 13.2 0.1 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Rhodanese PF00581.15 KFP07303.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain GAS PF13851.1 KFP07305.1 - 0.014 14.6 15.7 0.4 9.8 4.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0240 PF06784.6 KFP07305.1 - 0.018 14.7 4.4 0.02 14.5 3.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Tropomyosin PF00261.15 KFP07305.1 - 0.042 12.9 12.2 0.066 12.2 8.5 1.3 1 0 0 1 1 1 0 Tropomyosin GCR PF02155.10 KFP07305.1 - 0.079 11.6 0.2 0.089 11.5 0.2 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor DUF4351 PF14261.1 KFP07305.1 - 0.082 12.7 0.4 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) Baculo_PEP_C PF04513.7 KFP07305.1 - 0.11 12.2 5.7 1.1 9.1 4.0 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_C65 PF10275.4 KFP07305.1 - 0.36 10.1 3.3 0.38 10.0 2.3 1.1 1 0 0 1 1 1 0 Peptidase C65 Otubain KIAA1430 PF13879.1 KFP07305.1 - 0.36 11.2 6.3 0.5 10.8 3.7 1.7 1 1 0 1 1 1 0 KIAA1430 homologue Fmp27_WPPW PF10359.4 KFP07305.1 - 0.42 8.9 6.0 0.46 8.8 4.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain APG6 PF04111.7 KFP07305.1 - 0.93 8.4 12.4 1 8.3 8.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 LMBR1 PF04791.11 KFP07305.1 - 1.3 7.4 4.5 1.4 7.3 3.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2992 PF11208.3 KFP07305.1 - 1.3 8.8 8.1 1.5 8.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) MerR-DNA-bind PF09278.6 KFP07305.1 - 2.2 8.7 8.7 4 7.8 0.4 2.5 2 1 0 2 2 2 0 MerR, DNA binding XhlA PF10779.4 KFP07305.1 - 2.3 8.2 13.7 1.5e+03 -0.9 9.5 2.2 1 1 0 1 1 1 0 Haemolysin XhlA H-kinase_dim PF02895.9 KFP07305.1 - 2.8 8.3 5.8 16 5.8 4.0 2.0 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF1664 PF07889.7 KFP07305.1 - 3.4 7.4 6.7 8.4 6.2 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 KFP07305.1 - 3.9 7.0 9.8 5 6.6 6.8 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KFP07305.1 - 4.3 7.7 10.8 8.4 6.7 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ERM PF00769.14 KFP07305.1 - 4.7 6.6 14.5 5.2 6.5 10.0 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family WW PF00397.21 KFP07306.1 - 3.1e-14 52.4 16.1 2.7e-09 36.7 3.4 3.5 3 0 0 3 3 3 2 WW domain MBD PF01429.14 KFP07306.1 - 0.076 12.5 0.1 7.9 6.0 0.0 2.6 2 0 0 2 2 2 0 Methyl-CpG binding domain Suppressor_APC PF11414.3 KFP07306.1 - 0.98 9.2 7.5 0.55 10.0 2.8 2.2 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein GBP PF02263.14 KFP07307.1 - 5.1e-93 310.8 0.2 6.8e-93 310.4 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 KFP07307.1 - 2.1e-06 27.1 0.1 3.3e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Tic20 PF09685.5 KFP07307.1 - 0.014 15.3 0.9 0.035 14.0 0.7 1.6 1 0 0 1 1 1 0 Tic20-like protein DUF1977 PF09320.6 KFP07307.1 - 0.11 12.7 0.6 0.28 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) CNH PF00780.17 KFP07308.1 - 2.3e-78 263.3 0.8 4.3e-78 262.5 0.5 1.5 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFP07308.1 - 3.4e-57 193.5 0.0 5e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07308.1 - 6.9e-35 120.3 0.0 1.2e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP07308.1 - 0.0011 17.9 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KFP07309.1 - 5.2e-79 265.0 0.0 6.1e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07309.1 - 3.6e-36 124.5 0.0 2.7e-35 121.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP07309.1 - 0.02 13.8 0.0 0.38 9.6 0.0 2.2 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 KFP07309.1 - 0.032 13.9 0.2 0.23 11.1 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFP07309.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 LRR_8 PF13855.1 KFP07310.1 - 0.0028 17.3 1.6 0.28 10.9 0.0 2.6 3 0 0 3 3 3 2 Leucine rich repeat DAO PF01266.19 KFP07311.1 - 8.5e-58 195.9 0.0 9.9e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFP07311.1 - 0.0001 22.4 0.0 0.35 10.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFP07311.1 - 0.0004 20.3 0.1 0.0012 18.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFP07311.1 - 0.00042 19.4 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KFP07311.1 - 0.1 12.4 0.0 2.1 8.1 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RasGEF PF00617.14 KFP07312.1 - 4.2e-51 173.3 0.8 9.5e-51 172.2 0.6 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFP07312.1 - 1.1e-31 109.0 1.2 1.2e-30 105.6 0.0 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif RhoGEF PF00621.15 KFP07312.1 - 2.2e-17 63.5 2.4 2.2e-17 63.5 1.7 2.2 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 KFP07312.1 - 2.1e-11 43.9 0.3 1.5e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 PH domain Histone PF00125.19 KFP07312.1 - 1.6e-07 31.3 0.0 6.3e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PH_10 PF15411.1 KFP07312.1 - 0.0072 16.4 0.2 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 KFP07312.1 - 0.054 13.6 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Methyltransf_16 PF10294.4 KFP07313.1 - 5e-51 172.5 0.0 5.9e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFP07313.1 - 4.7e-08 32.9 0.0 5.7e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP07313.1 - 1.5e-05 25.5 0.0 2.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP07313.1 - 0.00031 20.1 0.1 0.00043 19.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 KFP07313.1 - 0.0012 18.3 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KFP07313.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP07313.1 - 0.0026 18.1 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP07313.1 - 0.0027 17.7 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFP07313.1 - 0.069 12.6 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KFP07313.1 - 0.078 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KFP07313.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TAT_signal PF10518.4 KFP07313.1 - 2.5 8.3 8.1 0.15 12.0 2.0 1.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Arf PF00025.16 KFP07316.1 - 3.9e-77 257.4 0.0 4.3e-77 257.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP07316.1 - 1.4e-14 53.7 0.0 1.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP07316.1 - 2.5e-13 49.6 0.0 3.1e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFP07316.1 - 1.1e-11 44.0 1.5 4e-08 32.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFP07316.1 - 9.8e-11 41.2 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFP07316.1 - 4.6e-08 33.5 0.0 6.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFP07316.1 - 0.0002 21.2 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP07316.1 - 0.0019 17.6 0.1 0.013 14.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KFP07316.1 - 0.0082 15.2 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ion_trans PF00520.26 KFP07317.1 - 9e-192 632.2 87.4 5.4e-64 215.1 7.3 4.8 4 0 0 4 4 4 4 Ion transport protein Na_trans_assoc PF06512.8 KFP07317.1 - 3.7e-38 131.8 5.4 3.7e-38 131.8 3.7 2.1 2 0 0 2 2 2 1 Sodium ion transport-associated PKD_channel PF08016.7 KFP07317.1 - 4.1e-07 28.7 5.8 4.1e-07 28.7 4.0 10.1 8 3 2 10 10 10 8 Polycystin cation channel IQ PF00612.22 KFP07317.1 - 0.029 13.9 0.7 0.098 12.3 0.5 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif NPCC PF08058.6 KFP07317.1 - 2.6 7.8 7.4 0.44 10.3 0.1 3.6 4 0 0 4 4 4 0 Nuclear pore complex component DUF3337 PF11816.3 KFP07318.1 - 5.8e-83 279.0 0.1 8.3e-83 278.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.27 KFP07318.1 - 2.2e-43 144.5 6.0 3.3e-08 33.1 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFP07318.1 - 0.0054 15.5 2.0 5.9 5.5 0.0 3.9 1 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 KFP07318.1 - 0.025 12.7 6.0 3.1 5.8 1.1 4.0 1 1 1 3 3 3 0 Nucleoporin Nup120/160 LIM PF00412.17 KFP07321.1 - 1.4e-08 34.6 10.3 1.6e-08 34.4 7.1 1.0 1 0 0 1 1 1 1 LIM domain DUF2685 PF10886.3 KFP07321.1 - 0.28 11.2 9.7 0.45 10.5 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2685) zf-RING_2 PF13639.1 KFP07321.1 - 0.54 10.1 9.1 0.73 9.7 6.3 1.4 1 1 0 1 1 1 0 Ring finger domain Rad50_zn_hook PF04423.9 KFP07321.1 - 0.63 9.5 4.2 1.1 8.8 2.9 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF2175 PF09943.4 KFP07321.1 - 2.1 8.4 5.6 1.8 8.6 2.3 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Sugar_tr PF00083.19 KFP07322.1 - 3.7e-39 134.5 12.1 5.1e-39 134.1 8.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP07322.1 - 6.2e-37 127.1 35.0 2.1e-32 112.2 15.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFP07322.1 - 1.1e-05 23.9 16.7 1.3e-05 23.7 1.3 3.3 3 1 0 4 4 4 2 MFS/sugar transport protein Tr-sialidase_C PF11052.3 KFP07322.1 - 8.1 6.4 11.7 1.2 9.0 0.7 2.8 2 0 0 2 2 2 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal MFS_1 PF07690.11 KFP07323.1 - 7.8e-23 80.7 51.9 1.2e-18 67.0 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP07323.1 - 4.2e-16 58.5 24.4 1.7e-09 36.8 6.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KFP07323.1 - 0.00037 19.0 3.0 0.00037 19.0 2.1 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein Pkinase PF00069.20 KFP07324.1 - 1.9e-62 210.7 0.0 2.4e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07324.1 - 7.3e-45 153.0 0.0 1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.3 KFP07324.1 - 1e-12 47.4 0.0 1.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C terminal Kinase-like PF14531.1 KFP07324.1 - 0.00036 19.5 0.0 0.00069 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TIR PF01582.15 KFP07325.1 - 5.6e-20 71.2 0.3 7.7e-20 70.7 0.2 1.2 1 0 0 1 1 1 1 TIR domain TIR_2 PF13676.1 KFP07325.1 - 5.3e-13 48.9 0.0 7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 TIR domain ETC_C1_NDUFA4 PF04800.7 KFP07325.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 ETC complex I subunit conserved region Thiolase_N PF00108.18 KFP07326.1 - 2.3e-88 295.6 1.1 3.3e-88 295.0 0.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFP07326.1 - 8.3e-50 167.3 0.2 1.9e-49 166.1 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFP07326.1 - 0.00026 20.6 1.1 0.058 13.0 0.1 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KFP07326.1 - 0.00029 20.4 0.5 0.00099 18.6 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KFP07326.1 - 0.00031 20.6 0.0 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PapD-like PF14874.1 KFP07327.1 - 5.1e-05 23.1 0.2 0.23 11.4 0.0 3.7 4 0 0 4 4 4 2 Flagellar-associated PapD-like MYCBPAP PF14646.1 KFP07327.1 - 0.029 13.1 3.2 0.32 9.6 0.0 3.5 5 0 0 5 5 5 0 MYCBP-associated protein family PI-PLC-X PF00388.14 KFP07328.1 - 6.3e-69 230.0 0.1 1.4e-68 228.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFP07328.1 - 1.4e-46 157.2 0.0 3e-46 156.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFP07328.1 - 8.7e-23 80.1 0.1 8.7e-23 80.1 0.1 2.4 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFP07328.1 - 7.3e-20 70.6 0.3 1.5e-19 69.6 0.2 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_10 PF14788.1 KFP07328.1 - 9e-06 25.2 0.7 2.1e-05 24.0 0.5 1.7 1 0 0 1 1 1 1 EF hand Gelsolin PF00626.17 KFP07329.1 - 8.1e-103 336.2 0.0 7.9e-20 70.3 0.0 6.2 6 0 0 6 6 6 6 Gelsolin repeat NIF PF03031.13 KFP07330.1 - 6.8e-51 172.0 0.0 9.3e-51 171.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Yae1_N PF09811.4 KFP07331.1 - 3.3e-14 52.1 40.4 1.4e+03 -1.2 28.0 4.0 1 1 0 1 1 1 0 Essential protein Yae1, N terminal tRNA-synt_2b PF00587.20 KFP07332.1 - 6.2e-71 237.5 0.0 1.2e-70 236.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFP07332.1 - 1.5e-23 82.5 0.2 9.8e-23 79.9 0.0 2.3 2 1 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.15 KFP07332.1 - 4.3e-10 39.0 5.7 1.5e-09 37.4 3.9 2.0 1 0 0 1 1 1 1 WHEP-TRS domain OS-D PF03392.8 KFP07332.1 - 0.0032 17.4 0.4 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 Insect pheromone-binding family, A10/OS-D zf-C2H2 PF00096.21 KFP07334.1 - 6.3e-38 126.8 53.9 2.6e-08 33.7 0.8 6.1 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP07334.1 - 1.1e-29 101.2 50.8 2.6e-09 36.8 0.3 7.2 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP07334.1 - 1.3e-24 84.6 47.7 2.1e-06 27.6 0.7 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP07334.1 - 1.6e-12 46.8 38.5 0.0004 20.1 0.6 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KFP07334.1 - 3.4e-06 26.9 34.0 0.0092 15.9 3.4 5.8 3 1 2 5 5 5 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFP07334.1 - 3.3e-05 23.5 29.9 0.011 15.5 1.7 3.6 3 0 0 3 3 3 2 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFP07334.1 - 0.00011 21.6 31.2 1.3 8.6 0.2 6.0 4 1 1 5 5 5 3 zinc-ribbon domain C1_4 PF07975.7 KFP07334.1 - 0.00014 21.8 21.3 0.046 13.7 3.9 4.5 1 1 4 5 5 5 2 TFIIH C1-like domain GAGA PF09237.6 KFP07334.1 - 0.00023 20.6 18.0 0.046 13.3 0.1 5.0 2 2 3 5 5 5 2 GAGA factor zf-Di19 PF05605.7 KFP07334.1 - 0.00027 20.9 23.8 0.075 13.1 0.4 3.8 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFP07334.1 - 0.00035 20.6 22.6 0.73 10.0 0.0 5.6 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding CpXC PF14353.1 KFP07334.1 - 0.00038 20.4 22.2 1.8 8.5 0.1 5.6 2 1 4 6 6 6 1 CpXC protein zinc_ribbon_4 PF13717.1 KFP07334.1 - 0.00057 19.5 31.0 2.2 8.0 0.1 6.0 5 1 0 5 5 5 2 zinc-ribbon domain Prok-RING_1 PF14446.1 KFP07334.1 - 0.00073 19.2 18.7 5.9 6.6 0.1 6.0 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 FYDLN_acid PF09538.5 KFP07334.1 - 0.0017 18.9 15.6 3 8.4 0.1 5.6 1 1 4 5 5 5 1 Protein of unknown function (FYDLN_acid) SprT-like PF10263.4 KFP07334.1 - 0.0021 17.7 21.8 0.24 11.0 0.6 3.3 1 1 1 3 3 3 2 SprT-like family Elf1 PF05129.8 KFP07334.1 - 0.0026 17.3 22.4 0.021 14.5 0.5 4.0 1 1 2 3 3 3 2 Transcription elongation factor Elf1 like DNA_RNApol_7kD PF03604.8 KFP07334.1 - 0.005 16.2 27.0 0.32 10.5 0.8 6.1 5 1 0 5 5 5 2 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 KFP07334.1 - 0.016 15.0 29.0 22 4.9 10.9 4.1 2 2 0 2 2 2 0 Double zinc ribbon zf-ISL3 PF14690.1 KFP07334.1 - 0.021 14.8 33.0 0.35 10.9 0.2 6.2 6 0 0 6 6 6 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.14 KFP07334.1 - 0.026 14.2 22.3 0.047 13.3 0.8 4.0 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C2HC_2 PF13913.1 KFP07334.1 - 0.067 12.8 0.8 0.067 12.8 0.5 6.6 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFP07334.1 - 0.072 13.1 24.1 1 9.4 0.1 5.2 6 0 0 6 6 5 0 zinc-finger zinc-ribbons_6 PF07191.7 KFP07334.1 - 0.081 12.7 23.4 2.3 8.0 3.0 5.2 1 1 3 4 4 4 0 zinc-ribbons DUF1610 PF07754.6 KFP07334.1 - 0.09 12.9 0.6 0.09 12.9 0.4 6.2 6 0 0 6 6 6 0 Domain of unknown function (DUF1610) ADK_lid PF05191.9 KFP07334.1 - 0.16 11.6 24.9 0.25 11.0 1.3 5.5 4 2 0 4 4 4 0 Adenylate kinase, active site lid DUF329 PF03884.9 KFP07334.1 - 0.23 11.0 22.1 2.3 7.8 0.1 5.7 6 0 0 6 6 5 0 Domain of unknown function (DUF329) BolA PF01722.13 KFP07334.1 - 0.24 11.3 12.5 3.8 7.5 0.0 4.8 2 2 3 6 6 6 0 BolA-like protein Cren7 PF11520.3 KFP07334.1 - 0.24 11.0 1.9 80 2.9 0.0 4.2 5 0 0 5 5 4 0 Chromatin protein Cren7 A2L_zn_ribbon PF08792.5 KFP07334.1 - 0.3 10.5 27.6 2.3 7.7 0.1 6.0 6 0 0 6 6 6 0 A2L zinc ribbon domain LIM PF00412.17 KFP07334.1 - 0.38 10.8 24.4 0.11 12.5 0.6 5.0 2 1 3 5 5 5 0 LIM domain Terminase_GpA PF05876.7 KFP07334.1 - 0.39 8.9 22.9 0.028 12.7 0.8 3.0 2 1 1 3 3 3 0 Phage terminase large subunit (GpA) zf-DNA_Pol PF08996.5 KFP07334.1 - 0.4 10.0 21.4 0.075 12.3 2.0 3.2 1 1 2 3 3 3 0 DNA Polymerase alpha zinc finger zinc_ribbon_2 PF13240.1 KFP07334.1 - 0.46 10.0 35.0 0.18 11.3 2.3 5.5 4 2 0 4 4 4 0 zinc-ribbon domain TFIIS_C PF01096.13 KFP07334.1 - 0.62 9.7 32.3 4.3 7.0 0.1 6.2 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.1 KFP07334.1 - 0.87 8.8 34.6 0.91 8.8 0.2 6.1 6 0 0 6 6 6 0 zinc-ribbon domain YhfH PF14149.1 KFP07334.1 - 4.5 7.1 32.3 6.1 6.7 0.1 6.2 5 1 1 6 6 6 0 YhfH-like protein RRN7 PF11781.3 KFP07334.1 - 4.5 6.8 19.5 9.2 5.8 0.1 5.5 6 0 0 6 6 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_ribbon_recom PF13408.1 KFP07334.1 - 8 6.8 31.9 0.55 10.5 0.3 4.9 1 1 2 4 4 3 0 Recombinase zinc beta ribbon domain 7tm_2 PF00002.19 KFP07335.1 - 7.1e-79 264.3 23.2 8.7e-79 264.0 16.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP07335.1 - 3e-20 71.9 2.5 6.6e-20 70.8 1.7 1.6 1 0 0 1 1 1 1 Hormone receptor domain DUF2976 PF11190.3 KFP07335.1 - 5.7 6.5 7.4 25 4.5 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF4205 PF13898.1 KFP07337.1 - 5.6e-142 472.5 0.1 6.4e-142 472.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) MIP PF00230.15 KFP07338.1 - 5.7e-79 264.7 10.4 6.7e-79 264.5 7.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein 7tm_2 PF00002.19 KFP07339.1 - 2e-77 259.5 17.8 2.4e-77 259.2 12.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP07339.1 - 1.3e-21 76.3 1.3 3.2e-21 75.1 0.9 1.7 1 0 0 1 1 1 1 Hormone receptor domain Dicty_CAR PF05462.6 KFP07339.1 - 0.00052 19.0 16.5 0.00066 18.6 11.1 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KFP07341.1 - 3.8e-81 271.7 11.8 5.1e-81 271.3 8.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP07341.1 - 2e-07 30.9 0.1 2e-07 30.9 0.1 2.3 2 0 0 2 2 2 1 Hormone receptor domain Na_Ca_ex PF01699.19 KFP07341.1 - 8.3 6.0 10.1 0.13 11.9 1.5 2.0 2 1 0 2 2 2 0 Sodium/calcium exchanger protein 7tm_2 PF00002.19 KFP07342.1 - 1.9e-53 181.0 5.8 5.6e-34 117.2 0.2 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP07342.1 - 4.9e-21 74.4 1.9 1.2e-20 73.2 1.3 1.7 1 0 0 1 1 1 1 Hormone receptor domain Yae1_N PF09811.4 KFP07343.1 - 4.7e-10 38.8 24.0 1.7e-05 24.2 7.3 2.7 2 1 0 2 2 2 2 Essential protein Yae1, N terminal 7tm_2 PF00002.19 KFP07344.1 - 4.7e-80 268.1 23.0 6.2e-80 267.7 15.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.17 KFP07344.1 - 3.2e-22 78.2 2.9 7.7e-22 77.0 2.0 1.7 1 0 0 1 1 1 1 Hormone receptor domain DUF843 PF05814.6 KFP07344.1 - 0.46 10.3 3.4 0.65 9.8 0.1 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Longin PF13774.1 KFP07347.1 - 2.5e-15 55.7 0.0 4.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain 7tm_1 PF00001.16 KFP07348.1 - 9.8e-09 34.7 14.3 3.5e-08 32.8 9.9 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP07348.1 - 0.0065 15.6 6.6 0.0065 15.6 4.6 2.6 1 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.4 KFP07348.1 - 0.01 15.1 2.2 0.01 15.1 1.5 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc 7tm_1 PF00001.16 KFP07349.1 - 0.00016 20.9 14.5 0.00016 20.9 10.0 2.8 1 1 2 3 3 3 2 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.16 KFP07350.1 - 6.1e-07 28.8 20.0 1.3e-06 27.7 13.8 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TctB PF07331.6 KFP07350.1 - 0.087 12.4 6.9 0.18 11.4 4.7 1.5 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family 7TMR-DISM_7TM PF07695.6 KFP07350.1 - 0.37 10.4 20.4 0.32 10.6 9.7 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2830 PF11125.3 KFP07350.1 - 8.5 6.1 10.3 2.5 7.8 3.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2830) 7tm_1 PF00001.16 KFP07351.1 - 2.2e-10 40.1 21.3 6.3e-10 38.6 14.8 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP07351.1 - 0.0014 17.8 5.4 0.0014 17.8 3.7 2.8 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx Ras PF00071.17 KFP07352.1 - 3.2e-52 176.1 0.0 3.7e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP07352.1 - 1.5e-21 77.1 0.0 2e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP07352.1 - 4.1e-07 29.4 0.0 5.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP07352.1 - 0.0045 16.9 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KFP07352.1 - 0.0093 15.6 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KFP07352.1 - 0.019 14.9 0.9 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Gtr1_RagA PF04670.7 KFP07352.1 - 0.038 13.1 0.0 0.062 12.4 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFP07352.1 - 0.1 12.0 0.1 0.39 10.1 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 KFP07352.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KFP07352.1 - 0.13 12.2 0.2 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain zf-CXXC PF02008.15 KFP07354.1 - 1e-12 47.6 21.5 1e-12 47.6 14.9 2.8 2 0 0 2 2 2 1 CXXC zinc finger domain F-box PF00646.28 KFP07354.1 - 8.2e-09 34.8 11.5 1.3e-08 34.2 3.4 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFP07354.1 - 3e-08 33.2 6.7 6.5e-08 32.1 4.6 1.6 1 0 0 1 1 1 1 F-box-like JmjC PF02373.17 KFP07354.1 - 3e-05 24.2 4.0 0.00022 21.4 0.4 3.1 2 1 0 2 2 2 1 JmjC domain, hydroxylase LRR_6 PF13516.1 KFP07354.1 - 0.0003 20.5 9.4 2.9 8.2 0.1 6.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.28 KFP07354.1 - 0.0013 18.5 5.7 43 4.6 0.0 6.5 5 1 1 6 6 6 0 Leucine Rich Repeat Cupin_8 PF13621.1 KFP07354.1 - 0.05 13.1 0.2 0.3 10.5 0.1 2.0 1 1 0 1 1 1 0 Cupin-like domain Cupin_1 PF00190.17 KFP07354.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Cupin LRR_4 PF12799.2 KFP07354.1 - 2.1 8.0 13.5 16 5.2 0.1 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP07354.1 - 3.1 7.6 13.5 4.3 7.1 0.0 4.2 3 2 1 5 5 5 0 Leucine rich repeat Pkinase PF00069.20 KFP07356.1 - 3.2e-59 200.2 0.0 1.7e-58 197.8 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07356.1 - 1.3e-23 83.3 0.0 2.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 KFP07356.1 - 5.8e-18 65.1 3.5 1.2e-17 64.1 2.4 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain PH PF00169.24 KFP07356.1 - 1.7e-10 40.9 0.0 4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KFP07356.1 - 0.0044 16.0 0.0 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 KFP07356.1 - 0.0052 17.0 0.4 0.056 13.6 0.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain HTH_WhiA PF02650.9 KFP07356.1 - 0.053 13.9 0.4 0.14 12.5 0.2 1.7 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Gly_acyl_tr_N PF06021.6 KFP07357.1 - 3.2e-17 62.6 0.0 9.2e-09 35.0 0.0 2.1 2 0 0 2 2 2 2 Aralkyl acyl-CoA:amino acid N-acyltransferase Gly_acyl_tr_C PF08444.5 KFP07357.1 - 3.5e-06 26.9 0.0 5.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_1 PF00583.19 KFP07357.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Metallophos PF00149.23 KFP07358.1 - 1.6e-44 151.6 0.4 1.9e-44 151.5 0.3 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 KFP07359.1 - 8.6e-27 93.9 0.1 4.4e-26 91.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_C PF00433.19 KFP07359.1 - 5.7e-09 36.3 2.7 1.5e-08 35.0 1.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_Tyr PF07714.12 KFP07359.1 - 1.4e-07 30.8 0.0 2.8e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Mito_fiss_reg PF05308.6 KFP07359.1 - 9.8 5.4 9.7 17 4.6 6.7 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF1899 PF08953.6 KFP07360.1 - 4e-35 119.2 0.0 6.6e-35 118.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) DUF1900 PF08954.6 KFP07360.1 - 7.6e-31 106.4 0.0 1.4e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 KFP07360.1 - 2.4e-24 84.2 10.5 1.5e-09 37.3 0.7 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 KFP07360.1 - 0.0034 17.1 0.0 0.018 14.7 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A EF-hand_1 PF00036.27 KFP07361.1 - 1.6e-24 83.2 11.2 5.1e-08 31.6 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFP07361.1 - 1.3e-19 70.0 5.8 9.1e-11 41.7 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP07361.1 - 7.5e-19 67.1 10.5 2.1e-08 33.6 0.3 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KFP07361.1 - 4.6e-18 63.4 6.3 6.2e-07 28.7 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KFP07361.1 - 7.8e-17 59.7 16.3 9.4e-07 27.9 0.0 4.9 4 1 1 5 5 5 3 EF hand EF-hand_4 PF12763.2 KFP07361.1 - 0.0058 16.3 3.3 0.27 10.9 0.0 3.0 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFP07361.1 - 0.0082 16.0 0.2 0.65 9.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KFP07361.1 - 0.012 15.6 0.1 0.98 9.4 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 KFP07361.1 - 0.023 14.4 0.5 5.5 6.7 0.0 2.7 2 1 0 2 2 2 0 Tellurite resistance protein TerB Dockerin_1 PF00404.13 KFP07361.1 - 0.36 10.6 9.9 1.5 8.6 0.9 2.9 3 0 0 3 3 3 0 Dockerin type I repeat Oxysterol_BP PF01237.13 KFP07362.1 - 2.7e-25 88.6 1.8 3.2e-25 88.3 1.3 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Syntaxin PF00804.20 KFP07363.1 - 1.9e-33 114.6 8.7 3.5e-33 113.8 6.0 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.14 KFP07363.1 - 1.3e-10 40.7 4.9 4.8e-09 35.7 0.0 3.2 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 KFP07363.1 - 3.6e-06 26.9 7.1 9.8e-06 25.5 4.9 1.7 1 1 0 1 1 1 1 Syntaxin-like protein AAA_13 PF13166.1 KFP07363.1 - 0.027 12.9 7.7 0.036 12.5 5.4 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 KFP07363.1 - 0.04 14.3 3.5 0.093 13.1 1.8 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal APG6 PF04111.7 KFP07363.1 - 0.048 12.7 6.7 0.063 12.3 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 KFP07363.1 - 0.051 13.5 4.7 0.7 9.8 2.4 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) RP-C_C PF11800.3 KFP07363.1 - 0.065 12.9 5.2 0.094 12.4 3.2 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region Peptidase_C65 PF10275.4 KFP07363.1 - 0.078 12.3 2.3 0.11 11.8 1.6 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain Phage_GPO PF05929.6 KFP07363.1 - 0.09 12.0 4.6 0.15 11.3 3.2 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Apc4 PF12896.2 KFP07363.1 - 0.093 12.0 0.3 0.16 11.2 0.1 1.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 WXG100 PF06013.7 KFP07363.1 - 0.13 12.2 4.4 8.7 6.4 0.4 2.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG FlaC_arch PF05377.6 KFP07363.1 - 0.18 11.6 11.0 0.55 10.1 0.7 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 KFP07363.1 - 0.23 9.8 6.7 0.31 9.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DASH_Duo1 PF08651.5 KFP07363.1 - 0.36 10.4 3.1 5 6.7 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF1664 PF07889.7 KFP07363.1 - 1.2 8.9 5.0 1.4 8.6 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3560 PF12083.3 KFP07363.1 - 1.6 8.7 6.2 2.1 8.3 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3560) COG2 PF06148.6 KFP07363.1 - 2 8.3 7.8 3.4 7.5 0.8 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 KFP07363.1 - 2.5 5.8 5.9 3 5.5 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L16 PF00252.13 KFP07364.1 - 1.2e-24 86.6 0.0 1.6e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Cobalamin_bind PF01122.14 KFP07365.1 - 6e-20 71.1 0.0 7.8e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF4430 PF14478.1 KFP07365.1 - 2.9e-11 43.2 0.0 4.1e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) Bile_Hydr_Trans PF04775.9 KFP07366.1 - 1.9e-32 111.5 0.0 2.2e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA thioester hydrolase/BAAT N-terminal region BAAT_C PF08840.6 KFP07367.1 - 1.3e-52 178.6 0.0 1.4e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KFP07367.1 - 5.6e-06 25.7 0.0 0.00021 20.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFP07367.1 - 5.8e-06 26.1 0.0 9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP07367.1 - 0.0001 22.2 0.1 0.00057 19.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFP07367.1 - 0.0017 17.8 0.0 0.016 14.6 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Zona_pellucida PF00100.18 KFP07368.1 - 1.5e-55 188.5 0.0 2.5e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.13 KFP07368.1 - 0.044 13.4 7.2 0.048 13.2 3.3 2.4 2 0 0 2 2 2 0 Trefoil (P-type) domain WD40 PF00400.27 KFP07369.1 - 3.6e-44 147.1 11.7 2.6e-11 42.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat U-box PF04564.10 KFP07369.1 - 7.5e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain Nup160 PF11715.3 KFP07369.1 - 8.4e-05 20.9 1.1 0.0043 15.2 0.1 2.7 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFP07369.1 - 0.00021 19.7 0.0 0.24 9.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 KFP07369.1 - 0.00078 19.2 0.0 0.87 9.2 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF1830 PF08865.6 KFP07369.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Hydrolase PF00702.21 KFP07371.1 - 1.5e-28 100.6 0.0 6.2e-27 95.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFP07371.1 - 1.6e-23 82.9 0.0 2.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFP07371.1 - 2e-22 78.9 0.5 4.4e-22 77.8 0.4 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFP07371.1 - 8.3e-15 55.4 0.4 2.1e-14 54.1 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFP07371.1 - 6.9e-06 25.8 1.5 9.8e-06 25.3 0.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-H2C2_2 PF13465.1 KFP07373.1 - 4e-43 143.6 68.8 2.3e-08 33.8 0.3 9.6 9 1 0 9 9 9 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFP07373.1 - 4.6e-37 124.1 72.2 1.2e-06 28.5 1.1 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07373.1 - 3.9e-20 70.6 68.5 0.00016 21.7 1.2 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP07373.1 - 1.8e-06 27.6 44.0 0.029 14.2 0.2 8.6 8 1 0 8 8 8 4 C2H2-type zinc finger C1_4 PF07975.7 KFP07373.1 - 3e-05 23.9 27.4 0.0088 16.0 0.0 5.8 2 1 3 5 5 5 1 TFIIH C1-like domain C1_1 PF00130.17 KFP07373.1 - 0.0004 20.0 34.4 0.039 13.6 1.4 5.9 4 2 2 6 6 6 4 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 KFP07373.1 - 0.0025 17.7 38.3 0.45 10.5 2.2 7.4 4 3 2 6 6 6 2 Zinc ribbon domain FYDLN_acid PF09538.5 KFP07373.1 - 0.0057 17.2 13.6 2.2 8.8 0.1 5.6 1 1 3 5 5 5 1 Protein of unknown function (FYDLN_acid) zf-C2H2_jaz PF12171.3 KFP07373.1 - 0.014 15.4 41.3 2.2 8.5 0.1 7.7 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding BolA PF01722.13 KFP07373.1 - 0.02 14.8 2.6 7.5 6.5 0.0 3.5 2 1 1 3 3 3 0 BolA-like protein Elf1 PF05129.8 KFP07373.1 - 0.14 11.8 0.2 0.14 11.8 0.2 4.4 2 2 2 4 4 4 0 Transcription elongation factor Elf1 like XPA_N PF01286.13 KFP07373.1 - 0.16 11.7 27.4 8 6.2 0.1 7.6 8 0 0 8 8 8 0 XPA protein N-terminal zf-RING_3 PF14369.1 KFP07373.1 - 0.27 11.2 28.9 1.3 9.0 0.0 7.1 7 1 0 7 7 6 0 zinc-finger zf-ISL3 PF14690.1 KFP07373.1 - 0.81 9.7 39.2 2.7 8.1 1.1 7.3 7 0 0 7 7 7 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-AN1 PF01428.11 KFP07373.1 - 0.99 9.3 45.9 0.36 10.7 3.3 7.2 5 1 2 7 7 7 0 AN1-like Zinc finger DUF2180 PF09947.4 KFP07373.1 - 1.5 8.6 15.9 0.74 9.6 3.5 4.0 2 2 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-CHCC PF10276.4 KFP07373.1 - 1.8 8.4 14.6 0.46 10.3 0.1 4.5 5 0 0 5 5 5 0 Zinc-finger domain zf-IS66 PF13005.2 KFP07373.1 - 2.4 8.2 0.0 2.4 8.2 0.0 6.6 7 0 0 7 7 6 0 zinc-finger binding domain of transposase IS66 TFIIS_C PF01096.13 KFP07373.1 - 2.4 7.8 32.3 5.1 6.8 0.3 7.0 7 0 0 7 7 7 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 KFP07373.1 - 2.4 8.0 39.0 0.087 12.6 1.3 5.8 4 1 2 6 6 6 0 Transposase zinc-ribbon domain HypA PF01155.14 KFP07373.1 - 2.5 7.8 23.2 2.4 7.8 1.3 4.3 2 2 1 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF2688 PF10892.3 KFP07373.1 - 3.8 7.2 11.4 2.7 7.7 0.0 4.5 5 1 0 5 5 5 0 Protein of unknown function (DUF2688) YhfH PF14149.1 KFP07373.1 - 5.7 6.8 30.1 1.6 8.6 0.1 6.5 7 0 0 7 7 7 0 YhfH-like protein SPRY PF00622.23 KFP07374.1 - 1.8e-19 70.0 0.0 2.2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 SPRY domain PRY PF13765.1 KFP07374.1 - 3.3e-19 68.1 0.0 5.1e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 SPRY-associated domain M-inducer_phosp PF06617.8 KFP07375.1 - 9e-48 162.5 5.8 1.6e-47 161.8 4.0 1.4 1 0 0 1 1 1 1 M-phase inducer phosphatase Rhodanese PF00581.15 KFP07375.1 - 7.5e-16 58.4 0.0 1.7e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain MBOAT PF03062.14 KFP07376.1 - 1.9e-30 106.1 9.6 1.9e-30 106.1 6.7 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family UPF0004 PF00919.15 KFP07377.1 - 4.8e-21 74.4 0.0 9.7e-21 73.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.16 KFP07377.1 - 4.6e-20 72.4 0.2 2e-19 70.3 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.15 KFP07377.1 - 4.3e-06 26.4 0.0 8.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Hormone_1 PF00103.15 KFP07379.1 - 2.5e-74 249.2 0.1 2.8e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Neurensin PF14927.1 KFP07382.1 - 4e-51 172.1 0.0 4.8e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 Neurensin DUF624 PF04854.9 KFP07382.1 - 0.0081 15.9 1.2 0.037 13.8 0.3 2.1 1 1 1 2 2 2 1 Protein of unknown function, DUF624 COX8 PF02285.10 KFP07382.1 - 0.36 10.3 1.4 0.73 9.4 0.9 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII DCX PF03607.12 KFP07383.1 - 1.2e-42 143.3 0.0 6.9e-21 73.6 0.0 2.2 2 0 0 2 2 2 2 Doublecortin FG-GAP PF01839.18 KFP07385.1 - 2.9e-24 84.1 24.4 3.6e-07 29.6 0.3 5.4 5 0 0 5 5 5 4 FG-GAP repeat VCBS PF13517.1 KFP07385.1 - 7.3e-16 58.2 7.4 1e-07 32.1 0.6 3.9 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 KFP07385.1 - 0.00011 21.6 1.1 0.046 13.1 0.0 3.3 3 1 1 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region BBS2_Mid PF14783.1 KFP07385.1 - 0.0058 16.3 0.0 14 5.4 0.0 4.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region C2 PF00168.25 KFP07386.1 - 1e-34 118.1 0.0 2.5e-17 62.5 0.0 2.7 2 0 0 2 2 2 2 C2 domain PDZ PF00595.19 KFP07386.1 - 9e-11 41.8 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FYVE_2 PF02318.11 KFP07386.1 - 3.2e-07 30.2 6.8 9.5e-07 28.7 4.7 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger Asparaginase_2 PF01112.13 KFP07387.1 - 4.2e-77 258.9 4.5 5.6e-77 258.5 3.1 1.1 1 0 0 1 1 1 1 Asparaginase Glyco_transf_43 PF03360.11 KFP07388.1 - 9e-42 142.9 0.1 1e-41 142.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 43 ArfGap PF01412.13 KFP07389.1 - 6.6e-33 112.9 0.2 6.6e-33 112.9 0.1 2.1 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf Plasmodium_Vir PF05795.6 KFP07389.1 - 0.00021 20.6 1.6 0.0003 20.1 1.1 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein PIG-S PF10510.4 KFP07389.1 - 0.12 11.0 5.1 2.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF1674 PF07896.7 KFP07390.1 - 3.8e-18 65.4 5.9 5.7e-18 64.8 4.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF676 PF05057.9 KFP07391.1 - 5.2e-61 205.7 0.0 9.4e-61 204.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 KFP07391.1 - 2.2e-29 101.2 6.2 3.1e-18 65.6 1.5 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3657) PGAP1 PF07819.8 KFP07391.1 - 2.5e-05 23.9 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 KFP07391.1 - 8.2e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase LMBR1 PF04791.11 KFP07392.1 - 5.3e-16 58.2 17.5 1.2e-15 57.0 1.9 2.3 2 1 0 2 2 2 2 LMBR1-like membrane protein DUF4294 PF14127.1 KFP07392.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) PspB PF06667.7 KFP07392.1 - 0.42 10.5 9.3 0.36 10.8 0.3 3.7 3 0 0 3 3 3 0 Phage shock protein B 7tm_2 PF00002.19 KFP07393.1 - 3.4e-62 209.7 15.1 4.7e-62 209.2 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF3497 PF12003.3 KFP07393.1 - 2.2e-49 167.7 0.1 3.3e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3497) TSP_1 PF00090.14 KFP07393.1 - 3.9e-39 132.5 79.9 3.3e-12 46.3 7.5 5.0 5 0 0 5 5 5 4 Thrombospondin type 1 domain GPS PF01825.16 KFP07393.1 - 8.5e-14 51.3 2.5 8.5e-14 51.3 1.7 2.9 3 0 0 3 3 3 1 Latrophilin/CL-1-like GPS domain HRM PF02793.17 KFP07393.1 - 5.9e-08 32.6 0.4 5.9e-08 32.6 0.3 4.0 3 1 0 3 3 3 1 Hormone receptor domain NDUF_B12 PF08122.7 KFP07393.1 - 0.018 14.7 0.1 0.048 13.3 0.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Laminin_G_2 PF02210.19 KFP07395.1 - 4.3e-21 75.2 1.8 2.7e-16 59.7 0.1 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFP07395.1 - 1.2e-19 70.5 0.2 1.7e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.22 KFP07395.1 - 1.2e-18 66.7 48.2 1.1e-05 25.2 4.1 5.0 4 1 0 4 4 4 4 EGF-like domain EGF_2 PF07974.8 KFP07395.1 - 0.00019 21.4 58.4 0.045 13.9 8.3 4.9 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.2 KFP07395.1 - 0.36 10.9 30.1 0.47 10.6 2.0 6.2 4 1 0 4 4 4 0 Human growth factor-like EGF Laminin_G_2 PF02210.19 KFP07396.1 - 6e-38 129.7 0.2 2.7e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFP07396.1 - 4.1e-34 117.4 0.0 2.7e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Laminin G domain EGF PF00008.22 KFP07396.1 - 8.5e-08 32.0 13.8 0.0016 18.3 4.1 3.0 2 0 0 2 2 2 2 EGF-like domain Laminin_G_3 PF13385.1 KFP07396.1 - 2.1e-06 28.0 0.1 0.0014 18.8 0.0 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily FXa_inhibition PF14670.1 KFP07396.1 - 0.00014 21.9 15.6 0.0048 16.9 1.6 2.8 2 1 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.8 KFP07396.1 - 0.0042 17.1 25.2 0.07 13.3 8.3 3.1 2 1 0 2 2 2 2 EGF-like domain DUF3248 PF11609.3 KFP07396.1 - 0.11 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) hEGF PF12661.2 KFP07396.1 - 3.4 7.9 17.8 0.18 11.9 0.6 3.7 3 0 0 3 3 3 0 Human growth factor-like EGF TFIIS_M PF07500.9 KFP07397.1 - 1.3e-32 112.2 3.4 1.3e-32 112.2 2.3 2.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KFP07397.1 - 6.9e-22 78.1 0.0 3.6e-21 75.8 0.0 2.3 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 KFP07397.1 - 7.4e-10 38.3 10.1 2.2e-09 36.8 7.0 1.9 1 0 0 1 1 1 1 PHD-finger DUF1212 PF06738.7 KFP07397.1 - 1.2 8.5 0.0 2.5 7.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Y_phosphatase PF00102.22 KFP07398.1 - 2.5e-11 43.3 0.0 1.1e-06 28.1 0.0 2.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFP07398.1 - 1e-07 31.6 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KFP07398.1 - 0.013 15.7 0.2 0.2 11.9 0.1 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP07398.1 - 0.014 15.4 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_S13 PF02113.10 KFP07398.1 - 0.095 11.1 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Gln-synt_C PF00120.19 KFP07399.1 - 4.7e-49 166.8 0.0 9.5e-49 165.8 0.0 1.5 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KFP07399.1 - 8.7e-07 28.4 0.2 6e-06 25.7 0.1 2.3 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SPARC_Ca_bdg PF10591.4 KFP07400.1 - 2.8e-30 104.6 0.3 6.1e-30 103.5 0.2 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Thyroglobulin_1 PF00086.13 KFP07400.1 - 8.6e-17 60.2 5.7 8.6e-17 60.2 4.0 3.1 3 0 0 3 3 3 1 Thyroglobulin type-1 repeat Kazal_2 PF07648.10 KFP07400.1 - 8.9e-11 41.5 5.6 2.5e-10 40.1 3.9 1.8 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP07400.1 - 8.7e-10 38.4 5.3 4.9e-09 36.0 3.7 2.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Torsin PF06309.6 KFP07401.1 - 2.2e-40 137.4 0.9 2.4e-40 137.3 0.6 1.0 1 0 0 1 1 1 1 Torsin DUF815 PF05673.8 KFP07401.1 - 0.054 12.4 0.1 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KFP07401.1 - 0.064 12.7 0.0 0.077 12.4 0.0 1.3 1 1 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.9 KFP07401.1 - 0.1 11.5 0.1 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase 7tm_4 PF13853.1 KFP07402.1 - 6.3e-43 146.0 7.9 7.2e-43 145.8 5.5 1.0 1 0 0 1 1 1 1 Olfactory receptor 7tm_1 PF00001.16 KFP07402.1 - 0.00043 19.4 5.2 0.00053 19.1 3.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4519 PF15012.1 KFP07402.1 - 0.046 13.6 2.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) RhoGEF PF00621.15 KFP07404.1 - 1.3e-48 165.2 5.5 1.3e-48 165.2 3.8 1.6 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KFP07404.1 - 4e-13 48.7 0.2 8e-13 47.7 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP07404.1 - 1.8e-10 40.0 2.1 4.3e-10 38.8 1.5 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KFP07404.1 - 5.5e-10 39.3 0.7 1.2e-09 38.2 0.5 1.5 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 KFP07404.1 - 5.4e-08 32.2 0.0 1.3e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_5 PF15405.1 KFP07404.1 - 0.015 15.2 4.7 0.018 15.0 0.5 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain C1q PF00386.16 KFP07405.1 - 5.4e-39 133.0 0.1 6.8e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP07405.1 - 1e-29 101.8 82.0 1.5e-10 40.4 16.8 3.7 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Peptidase_M3 PF01432.15 KFP07406.1 - 2.3e-144 481.8 0.0 3.3e-144 481.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 FtsK_SpoIIIE PF01580.13 KFP07406.1 - 0.039 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family TNFR_c6 PF00020.13 KFP07408.1 - 5.5e-05 23.1 17.6 0.00015 21.7 2.9 5.3 6 2 0 6 6 6 2 TNFR/NGFR cysteine-rich region HEPN PF05168.9 KFP07409.1 - 7.7e-10 38.6 0.1 4.1e-09 36.3 0.1 2.4 1 0 0 1 1 1 1 HEPN domain HATPase_c_3 PF13589.1 KFP07409.1 - 7.8e-06 25.5 0.6 1.8 8.2 0.0 5.1 3 3 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4368 PF14287.1 KFP07409.1 - 0.002 17.9 0.0 0.006 16.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) DnaJ PF00226.26 KFP07409.1 - 0.011 15.5 0.2 0.034 13.8 0.1 1.9 1 0 0 1 1 1 0 DnaJ domain Sarcoglycan_1 PF04790.8 KFP07410.1 - 1.7e-107 358.5 0.0 1.9e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 Sarcoglycan complex subunit protein DUF2345 PF10106.4 KFP07410.1 - 0.0068 16.0 0.0 0.031 13.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) FGF PF00167.13 KFP07411.1 - 5.6e-46 155.2 0.2 6.7e-46 155.0 0.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor EF-hand_8 PF13833.1 KFP07412.1 - 2.4e-13 49.4 10.2 1.7e-09 37.1 0.1 5.0 5 1 0 5 5 5 2 EF-hand domain pair EF-hand_7 PF13499.1 KFP07412.1 - 1.6e-10 40.9 7.3 1.6e-05 24.9 0.2 3.9 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP07412.1 - 1.3e-09 36.6 11.8 0.00031 19.8 0.2 5.5 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.1 KFP07412.1 - 3.3e-08 32.7 7.3 0.002 17.8 0.1 4.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_4 PF12763.2 KFP07412.1 - 0.0046 16.6 3.4 0.12 12.1 0.2 3.4 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 KFP07412.1 - 0.024 13.9 4.7 3.4 7.1 0.1 4.0 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.4 KFP07412.1 - 0.046 13.7 0.2 7.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region zf-DHHC PF01529.15 KFP07413.1 - 7.6e-44 149.1 12.2 7.6e-44 149.1 8.4 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase HemY_N PF07219.8 KFP07413.1 - 0.79 9.3 0.0 0.79 9.3 0.0 2.5 2 1 1 3 3 3 0 HemY protein N-terminus Spt4 PF06093.8 KFP07413.1 - 1.2 9.0 6.3 2.4 8.0 4.4 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger MRP-63 PF14978.1 KFP07414.1 - 4.7e-38 129.5 4.3 5.4e-38 129.3 3.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosome protein 63 Annexin PF00191.15 KFP07415.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Annexin eIF-3c_N PF05470.7 KFP07415.1 - 0.11 10.5 3.1 0.15 10.1 2.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SAP18 PF06487.7 KFP07416.1 - 4.1e-25 87.9 0.0 4.6e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF2312 PF10073.4 KFP07416.1 - 0.082 12.2 0.0 4.6 6.6 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Pkinase PF00069.20 KFP07417.1 - 9e-58 195.4 0.1 2.7e-37 128.3 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07417.1 - 6.2e-29 100.8 0.1 1.7e-20 73.2 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase UBA PF00627.26 KFP07417.1 - 5.9e-05 22.7 0.4 0.00018 21.1 0.3 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Pkinase_C PF00433.19 KFP07417.1 - 0.00011 22.6 1.3 0.00031 21.2 0.9 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFP07417.1 - 0.0037 16.2 0.1 0.0096 14.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP07417.1 - 0.0073 16.0 0.2 0.062 13.0 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFP07417.1 - 0.037 13.1 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family N6-adenineMlase PF10237.4 KFP07419.1 - 1.4e-64 216.6 0.0 1.6e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 KFP07419.1 - 0.00069 19.0 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KFP07419.1 - 0.0013 18.3 0.0 0.0039 16.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP07419.1 - 0.042 13.8 0.0 0.052 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain IL17 PF06083.6 KFP07420.1 - 5.9e-29 99.9 0.5 8e-29 99.5 0.4 1.1 1 0 0 1 1 1 1 Interleukin-17 TPR_2 PF07719.12 KFP07421.1 - 1e-38 128.1 12.2 0.00013 21.6 0.1 11.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFP07421.1 - 1.8e-37 126.7 17.3 1.5e-12 46.9 0.9 7.1 5 1 1 7 7 6 4 TPR repeat TPR_1 PF00515.23 KFP07421.1 - 6e-32 107.9 31.8 1.7e-06 27.3 0.0 11.3 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFP07421.1 - 1.1e-29 102.1 22.9 6.4e-08 32.4 1.1 8.6 6 2 4 10 10 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 KFP07421.1 - 4.6e-27 91.6 4.8 0.00026 20.5 0.0 10.2 10 1 1 11 11 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFP07421.1 - 3.7e-22 78.4 3.9 2.3e-06 27.8 0.2 7.2 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFP07421.1 - 4.2e-21 75.0 0.0 7e-07 29.7 0.1 6.6 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFP07421.1 - 9.2e-21 72.8 18.3 0.028 14.8 0.1 11.3 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFP07421.1 - 2e-19 68.3 0.1 0.093 13.4 0.0 9.4 5 2 5 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFP07421.1 - 3.6e-18 63.8 30.9 0.0015 18.2 0.1 11.2 10 2 2 12 12 12 4 Tetratricopeptide repeat Apc3 PF12895.2 KFP07421.1 - 1.1e-15 57.5 18.2 3.3e-06 27.1 2.0 6.1 3 3 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KFP07421.1 - 1.8e-10 40.3 13.1 0.12 12.3 0.1 8.5 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP07421.1 - 7.7e-08 31.9 21.8 0.036 14.2 0.2 9.8 10 1 0 10 10 9 1 Tetratricopeptide repeat TPR_21 PF09976.4 KFP07421.1 - 7.8e-06 25.8 10.0 0.0006 19.7 3.6 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP07421.1 - 1.5e-05 24.7 0.0 2.2 8.2 0.0 5.4 5 2 1 6 6 5 1 Tetratricopeptide repeat Sel1 PF08238.7 KFP07421.1 - 0.00038 20.9 15.9 3.5 8.3 0.0 7.4 8 0 0 8 8 6 1 Sel1 repeat TPR_20 PF14561.1 KFP07421.1 - 0.0021 18.1 6.1 0.7 10.0 0.0 5.3 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFP07421.1 - 0.0035 16.4 11.7 0.038 13.0 5.0 3.8 2 2 1 4 4 4 1 Tetratricopeptide repeat FumaraseC_C PF10415.4 KFP07421.1 - 0.0097 15.9 0.2 1.1 9.4 0.1 3.2 2 0 0 2 2 2 1 Fumarase C C-terminus Fis1_TPR_C PF14853.1 KFP07421.1 - 0.025 14.4 9.4 13 5.7 0.0 6.2 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 KFP07421.1 - 0.09 13.2 0.0 64 4.4 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.13 KFP07421.1 - 0.1 12.5 22.9 0.66 9.9 0.5 7.2 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain Como_LCP PF02247.11 KFP07421.1 - 0.1 10.9 0.8 0.17 10.2 0.5 1.2 1 0 0 1 1 1 0 Large coat protein 3HCDH_N PF02737.13 KFP07422.1 - 1.9e-47 161.2 0.0 2.5e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFP07422.1 - 6e-15 55.4 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Connexin PF00029.14 KFP07423.1 - 8.6e-51 170.5 0.2 8.6e-51 170.5 0.1 2.0 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFP07423.1 - 9.3e-33 111.8 5.7 2.1e-32 110.7 4.0 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain 7tm_1 PF00001.16 KFP07423.1 - 0.013 14.6 4.4 0.054 12.6 0.4 2.1 1 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.1 KFP07423.1 - 0.023 15.0 0.3 18 5.8 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain COX6A PF02046.10 KFP07423.1 - 0.039 13.8 3.8 0.078 12.8 0.1 2.6 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VIa Connexin PF00029.14 KFP07424.1 - 8.5e-51 170.5 0.3 8.5e-51 170.5 0.2 1.8 2 1 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFP07424.1 - 1.4e-31 108.1 4.7 3.1e-31 106.9 3.2 1.6 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain MFS_1 PF07690.11 KFP07424.1 - 0.038 12.7 0.5 0.063 11.9 0.4 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily COX6A PF02046.10 KFP07424.1 - 0.13 12.1 0.8 1.4 8.8 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIa Connexin PF00029.14 KFP07425.1 - 1.7e-53 179.1 1.1 2.7e-53 178.5 0.1 1.7 2 0 0 2 2 2 1 Connexin Connexin_CCC PF10582.4 KFP07425.1 - 1.8e-33 114.1 2.7 3.2e-33 113.3 1.9 1.4 1 0 0 1 1 1 1 Gap junction channel protein cysteine-rich domain Adeno_E3_14_5 PF04834.7 KFP07425.1 - 0.093 13.1 0.3 0.093 13.1 0.2 4.6 4 1 0 4 4 4 0 Early E3 14.5 kDa protein zf-FCS PF06467.9 KFP07426.1 - 5e-73 240.5 115.2 4e-12 45.5 2.2 10.5 10 0 0 10 10 10 10 MYM-type Zinc finger with FCS sequence motif DUF3504 PF12012.3 KFP07426.1 - 6.9e-68 227.7 0.4 6.9e-68 227.7 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3504) Arc_trans_TRASH PF08394.5 KFP07426.1 - 0.00021 21.4 5.1 0.00021 21.4 3.5 7.8 8 1 0 8 8 8 1 Archaeal TRASH domain Ribosomal_L24e PF01246.15 KFP07426.1 - 0.058 13.2 31.0 0.059 13.2 0.3 6.8 6 1 1 7 7 7 0 Ribosomal protein L24e YHS PF04945.8 KFP07426.1 - 0.35 10.7 0.0 0.33 10.8 0.4 8.2 9 0 0 9 9 9 0 YHS domain RRM_1 PF00076.17 KFP07427.1 - 1.2e-33 114.5 0.0 4.5e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07427.1 - 1.8e-22 79.0 0.0 1.4e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.6 KFP07427.1 - 5.2e-13 49.1 6.5 4.2e-12 46.2 0.5 3.2 2 1 1 3 3 3 1 NOPS (NUC059) domain RRM_5 PF13893.1 KFP07427.1 - 8.3e-13 47.9 0.0 1.4e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3256 PF11644.3 KFP07427.1 - 0.12 11.8 0.5 0.17 11.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Aldedh PF00171.17 KFP07427.1 - 2.2 6.5 6.8 2.9 6.1 4.7 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Ank_2 PF12796.2 KFP07428.1 - 3.8e-26 91.2 7.0 6.8e-14 51.9 1.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07428.1 - 4.3e-20 70.4 3.2 2.6e-07 30.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFP07428.1 - 1.3e-19 69.7 0.1 2.1e-09 37.3 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP07428.1 - 1.2e-17 63.8 0.8 7.8e-08 32.6 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07428.1 - 6.6e-15 53.7 2.0 3.2e-05 23.7 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Chromo PF00385.19 KFP07428.1 - 1.9e-10 40.2 0.7 8.6e-10 38.1 0.5 2.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2852 PF11014.3 KFP07429.1 - 0.004 17.1 16.4 0.015 15.2 6.0 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF2852) FlgN PF05130.7 KFP07429.1 - 0.0084 16.3 3.0 0.0084 16.3 2.1 4.4 4 1 0 4 4 4 1 FlgN protein Calici_MSP PF05752.6 KFP07429.1 - 1.6 8.3 9.6 13 5.3 2.4 2.9 2 0 0 2 2 2 0 Calicivirus minor structural protein Tcp10_C PF07202.8 KFP07430.1 - 8.5e-90 299.0 8.7 8.5e-90 299.0 6.0 1.3 2 0 0 2 2 2 1 T-complex protein 10 C-terminus DUF4520 PF15016.1 KFP07430.1 - 5.6e-05 22.6 0.1 0.54 9.8 0.0 3.7 1 1 1 3 3 3 2 Domain of unknown function (DUF4520) MORN_2 PF07661.8 KFP07430.1 - 0.00018 21.1 4.6 45 4.5 0.1 6.9 6 2 2 8 8 8 0 MORN repeat variant Acyltransferase PF01553.16 KFP07430.1 - 0.054 12.9 0.0 1.3 8.4 0.0 2.3 1 1 0 2 2 2 0 Acyltransferase Plant_vir_prot PF01307.12 KFP07430.1 - 0.062 13.0 1.7 4 7.2 0.0 2.8 1 1 2 3 3 3 0 Plant viral movement protein Rib PF08428.5 KFP07430.1 - 0.7 9.6 5.4 18 5.1 0.1 4.4 3 1 0 4 4 4 0 Rib/alpha-like repeat TUDOR PF00567.19 KFP07431.1 - 7.8e-87 287.2 8.9 1.1e-20 73.6 0.1 7.6 7 1 0 7 7 7 5 Tudor domain Agenet PF05641.7 KFP07431.1 - 0.00025 21.1 0.0 10 6.3 0.0 4.3 3 0 0 3 3 3 2 Agenet domain STAS PF01740.16 KFP07431.1 - 0.0013 18.1 0.0 0.0041 16.5 0.0 1.8 1 0 0 1 1 1 1 STAS domain Tudor-knot PF11717.3 KFP07431.1 - 0.011 15.3 0.0 11 5.8 0.0 3.3 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain RA PF00788.18 KFP07432.1 - 1.6e-12 47.7 0.0 9.6e-12 45.2 0.0 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 KFP07432.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 TUG-UBL1 PF11470.3 KFP07432.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG PH PF00169.24 KFP07432.1 - 0.16 12.2 4.4 0.44 10.7 0.7 2.5 2 1 0 2 2 2 0 PH domain RhoGAP PF00620.22 KFP07433.1 - 1.4e-39 135.1 0.0 1.8e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF2183 PF09949.4 KFP07433.1 - 0.0082 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Fer2 PF00111.22 KFP07435.1 - 9.7e-08 31.6 0.2 1.3e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-CHY PF05495.7 KFP07435.1 - 0.033 14.3 0.7 0.091 12.9 0.5 1.6 1 1 0 1 1 1 0 CHY zinc finger ERM PF00769.14 KFP07436.1 - 8.6e-83 277.6 50.6 8.6e-83 277.6 35.0 2.6 2 1 1 3 3 3 1 Ezrin/radixin/moesin family FERM_C PF09380.5 KFP07436.1 - 2.5e-33 114.1 0.0 7.1e-33 112.6 0.0 1.9 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_M PF00373.13 KFP07436.1 - 3.6e-26 91.7 1.8 3.6e-26 91.7 1.2 3.6 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFP07436.1 - 2.8e-19 68.9 0.3 2.8e-19 68.9 0.2 2.9 3 0 0 3 3 3 1 FERM N-terminal domain RNase_Zc3h12a PF11977.3 KFP07437.1 - 1.4e-64 216.5 0.0 2e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Omega-toxin PF06357.6 KFP07437.1 - 0.0095 15.5 4.8 0.018 14.6 3.3 1.3 1 0 0 1 1 1 1 Omega-atracotoxin RNase_Zc3h12a_2 PF14626.1 KFP07437.1 - 0.018 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 PF14608.1 KFP07437.1 - 0.67 10.0 10.0 1.1 9.3 6.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type TMEM154 PF15102.1 KFP07438.1 - 0.0028 17.3 0.1 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF1049 PF06305.6 KFP07438.1 - 0.004 16.6 0.1 0.0073 15.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) 7tm_1 PF00001.16 KFP07438.1 - 0.0068 15.5 0.0 0.0068 15.5 0.0 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Brr6_like_C_C PF10104.4 KFP07438.1 - 0.0069 15.8 1.8 0.011 15.2 1.2 1.3 1 1 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain EphA2_TM PF14575.1 KFP07438.1 - 0.032 14.6 0.2 0.048 14.0 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PIRT PF15099.1 KFP07438.1 - 0.051 12.8 0.3 0.07 12.3 0.2 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Potyvirid-P3 PF13608.1 KFP07438.1 - 0.052 12.6 0.4 0.061 12.4 0.3 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein RELT PF12606.3 KFP07438.1 - 0.062 12.4 0.6 0.091 11.9 0.4 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF2681 PF10883.3 KFP07438.1 - 0.066 13.4 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3328 PF11807.3 KFP07438.1 - 0.067 12.8 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) SieB PF14163.1 KFP07438.1 - 0.087 12.3 0.2 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF3357 PF11837.3 KFP07438.1 - 0.093 12.5 0.1 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2663 PF10864.3 KFP07438.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) OAD_gamma PF04277.8 KFP07438.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ATP-synt_8 PF00895.15 KFP07438.1 - 0.16 12.1 0.6 0.34 11.1 0.4 1.5 1 0 0 1 1 1 0 ATP synthase protein 8 DEAD PF00270.24 KFP07439.1 - 7.4e-45 152.4 1.1 1.2e-44 151.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFP07439.1 - 8.1e-22 76.5 0.3 1.8e-21 75.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFP07439.1 - 1.4e-20 72.9 0.0 3.4e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAS_11 PF14598.1 KFP07439.1 - 0.038 13.9 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain Glyco_transf_90 PF05686.7 KFP07440.1 - 7.6e-86 288.2 0.3 9.6e-86 287.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.14 KFP07440.1 - 0.0039 17.7 0.0 0.0072 16.8 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat Glyco_trans_1_2 PF13524.1 KFP07440.1 - 0.039 14.2 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Thiolase_N PF00108.18 KFP07442.1 - 5.8e-102 340.1 2.3 7.9e-102 339.7 1.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFP07442.1 - 1.8e-46 156.5 2.6 5.5e-46 154.9 0.3 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFP07442.1 - 2.2e-05 24.0 3.2 2.2e-05 24.0 2.2 2.3 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Cullin PF00888.17 KFP07443.1 - 5.5e-165 550.2 18.0 8.1e-165 549.7 12.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFP07443.1 - 2.1e-20 72.3 7.8 5.8e-20 70.8 5.4 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Ras PF00071.17 KFP07444.1 - 1.3e-29 102.7 0.0 1.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP07444.1 - 0.0076 16.7 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein CENP-M PF11111.3 KFP07444.1 - 0.095 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Arf PF00025.16 KFP07444.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF914 PF06027.7 KFP07445.1 - 9.5e-146 484.9 21.6 1.1e-145 484.6 15.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFP07445.1 - 1.3e-09 38.1 30.4 8e-05 22.6 4.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KFP07445.1 - 5.7e-06 26.5 6.8 5.7e-06 26.5 4.7 2.6 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 KFP07445.1 - 0.00072 19.2 25.8 0.005 16.5 10.8 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KFP07445.1 - 0.0013 17.6 22.1 0.0017 17.3 15.3 1.1 1 0 0 1 1 1 1 UAA transporter family ELMO_CED12 PF04727.8 KFP07446.1 - 7.7e-50 168.7 0.0 1e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family 2OG-FeII_Oxy_2 PF13532.1 KFP07447.1 - 1.1e-22 80.8 0.0 2.3e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.7 KFP07447.1 - 5.5e-15 55.6 0.1 2.7e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 KFP07447.1 - 2.6e-09 37.2 0.0 5.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 KFP07447.1 - 1.4e-08 34.2 0.0 3.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.1 KFP07447.1 - 5.3e-07 29.3 0.0 1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP07447.1 - 5.4e-07 29.4 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP07447.1 - 5.6e-07 29.8 0.1 2.5e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain RRM_6 PF14259.1 KFP07447.1 - 2.4e-06 27.4 0.0 6.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07447.1 - 1.6e-05 24.6 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_8 PF05148.10 KFP07447.1 - 2.1e-05 24.2 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase DUF1891 PF09004.5 KFP07447.1 - 9.6e-05 21.6 0.1 0.00037 19.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1891) Methyltransf_12 PF08242.7 KFP07447.1 - 0.00012 22.4 0.0 0.00038 20.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFP07447.1 - 0.0024 17.0 0.0 0.0059 15.7 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFP07447.1 - 0.0026 18.3 0.1 0.007 16.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP07447.1 - 0.0039 17.2 0.1 0.0092 16.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFP07447.1 - 0.033 13.5 0.1 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW SYCE1 PF15233.1 KFP07448.1 - 2.7 7.9 10.0 0.23 11.3 2.9 2.0 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 VOMI PF03762.12 KFP07449.1 - 5.8e-33 114.2 0.6 6.9e-33 114.0 0.4 1.1 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) Aconitase PF00330.15 KFP07449.1 - 0.16 10.3 0.0 0.34 9.3 0.0 1.5 2 0 0 2 2 2 0 Aconitase family (aconitate hydratase) HNOBA PF07701.9 KFP07450.1 - 3.7e-63 212.6 2.4 1.7e-62 210.5 1.7 1.9 1 1 0 1 1 1 1 Heme NO binding associated Guanylate_cyc PF00211.15 KFP07450.1 - 1.1e-60 204.1 0.0 1.9e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOB PF07700.10 KFP07450.1 - 4.9e-16 58.7 0.2 7.5e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Heme NO binding ACPS PF01648.15 KFP07451.1 - 3.5e-17 62.2 0.0 3.1e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily BTB PF00651.26 KFP07452.1 - 2.6e-27 94.9 1.1 2.6e-27 94.9 0.8 2.3 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFP07452.1 - 8.1e-27 93.0 2.8 8.1e-27 93.0 2.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFP07452.1 - 8.3e-27 92.4 7.3 2e-07 30.4 0.0 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KFP07452.1 - 1.8e-26 91.1 4.1 1.1e-05 25.3 0.0 6.7 2 2 4 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KFP07452.1 - 2.6e-12 46.3 0.0 0.013 15.2 0.0 5.0 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KFP07452.1 - 3.4e-10 39.7 0.1 1.1 9.4 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP07452.1 - 7.5e-07 28.6 4.8 0.087 12.6 0.0 5.8 6 1 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 KFP07452.1 - 0.00069 19.5 0.1 2.8 8.0 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Myb_DNA-bind_5 PF13873.1 KFP07453.1 - 2.1e-23 81.9 6.1 8.6e-23 80.0 4.3 2.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFP07453.1 - 0.0079 16.2 2.0 0.02 15.0 1.4 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2125 PF09898.4 KFP07453.1 - 0.081 12.2 2.2 0.31 10.2 1.5 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) Flagellin_C PF00700.16 KFP07453.1 - 0.1 12.7 3.3 0.12 12.5 0.5 2.4 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Myb_DNA-binding PF00249.26 KFP07453.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain HALZ PF02183.13 KFP07453.1 - 0.17 11.6 39.6 0.26 11.0 1.3 5.9 3 2 3 6 6 6 0 Homeobox associated leucine zipper FtsL PF04999.8 KFP07453.1 - 3.2 7.5 34.1 1.9 8.2 4.9 4.3 1 1 3 4 4 4 0 Cell division protein FtsL ANF_receptor PF01094.23 KFP07454.1 - 8.9e-62 208.8 0.0 1.7e-61 207.9 0.0 1.5 2 0 0 2 2 2 1 Receptor family ligand binding region Lig_chan PF00060.21 KFP07454.1 - 4.3e-60 201.7 0.0 7e-60 201.0 0.0 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.4 KFP07454.1 - 5.8e-27 93.4 0.1 1.5e-26 92.1 0.1 1.8 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.15 KFP07454.1 - 1.4e-25 89.8 0.0 2.6e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Peripla_BP_6 PF13458.1 KFP07454.1 - 0.00014 21.3 0.0 0.0015 17.9 0.0 2.2 2 1 0 2 2 2 1 Periplasmic binding protein Actin PF00022.14 KFP07455.1 - 6.2e-152 505.5 0.0 7e-152 505.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFP07455.1 - 0.12 12.8 0.0 0.38 11.1 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Nucleoporin_C PF03177.9 KFP07457.1 - 7.3e-92 308.7 17.7 9.9e-92 308.3 12.3 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KFP07457.1 - 4.6e-20 71.7 1.2 8.2e-20 70.9 0.8 1.3 1 0 0 1 1 1 1 Nup133 N terminal like ABC_membrane PF00664.18 KFP07458.1 - 3.8e-56 190.5 6.8 5.4e-56 190.0 4.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFP07458.1 - 3.4e-33 114.8 0.0 7.8e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KFP07458.1 - 2e-07 30.4 0.0 6.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFP07458.1 - 3.2e-07 30.6 0.1 9e-06 25.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 KFP07458.1 - 0.00021 20.0 0.0 0.0074 14.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 KFP07458.1 - 0.00024 20.5 0.1 0.0025 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFP07458.1 - 0.00056 20.1 0.5 0.011 15.9 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFP07458.1 - 0.0007 19.6 1.0 0.0041 17.1 0.7 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KFP07458.1 - 0.00096 18.6 0.1 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFP07458.1 - 0.0021 18.1 0.3 0.027 14.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFP07458.1 - 0.0022 17.7 0.3 0.013 15.2 0.0 2.4 2 0 0 2 2 1 1 Part of AAA domain DUF258 PF03193.11 KFP07458.1 - 0.0068 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFP07458.1 - 0.0074 17.1 0.1 0.025 15.3 0.0 1.8 1 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KFP07458.1 - 0.0096 15.6 0.2 0.069 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KFP07458.1 - 0.056 13.3 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFP07458.1 - 0.063 12.8 0.0 0.59 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFP07458.1 - 0.075 12.9 0.2 0.28 11.1 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KFP07458.1 - 0.12 12.0 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KFP07458.1 - 0.15 12.3 0.0 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 KFP07459.1 - 4.6e-62 203.8 7.1 9.2e-13 47.5 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KFP07459.1 - 1e-39 135.8 3.0 1.5e-39 135.2 2.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 KFP07459.1 - 3.7e-06 25.3 0.6 0.001 17.2 0.1 2.9 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFP07459.1 - 0.066 12.2 0.0 0.41 9.7 0.0 2.2 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal CAGE1 PF15066.1 KFP07459.1 - 0.11 10.9 0.8 0.34 9.2 0.0 1.8 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family Glycos_transf_2 PF00535.21 KFP07460.1 - 5.2e-25 88.0 0.0 8.9e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP07460.1 - 2.5e-22 79.2 2.9 4.2e-22 78.4 2.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFP07460.1 - 4.1e-08 33.3 0.0 6.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFP07460.1 - 2.7e-06 26.7 0.0 5.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP07460.1 - 7.2e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFP07460.1 - 0.0001 22.6 0.1 0.0038 17.5 0.1 2.7 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DDE_Tnp_1_7 PF13843.1 KFP07461.1 - 1.2e-81 274.5 0.9 1.3e-81 274.3 0.6 1.0 1 0 0 1 1 1 1 Transposase IS4 HEPN PF05168.9 KFP07461.1 - 0.085 12.7 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 HEPN domain DUF3510 PF12022.3 KFP07462.1 - 2.2e-39 134.4 1.6 1.4e-38 131.8 0.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3510) COG2 PF06148.6 KFP07462.1 - 2.1e-09 37.3 5.7 1.4e-08 34.7 0.7 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 KFP07462.1 - 0.00065 19.4 3.4 0.0043 16.8 0.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KFP07462.1 - 0.26 11.0 1.1 7.1 6.4 0.0 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serpin PF00079.15 KFP07463.1 - 5.3e-58 196.9 0.0 6.9e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Peptidase_C2 PF00648.16 KFP07464.1 - 1e-138 461.3 0.3 2.2e-138 460.2 0.1 1.6 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.17 KFP07464.1 - 5.5e-58 194.7 0.0 8.6e-58 194.1 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_1 PF00036.27 KFP07464.1 - 1.5e-11 42.7 2.7 5.4e-05 22.2 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 KFP07464.1 - 4.1e-11 41.7 0.9 0.0017 18.0 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFP07464.1 - 2.3e-09 36.7 1.0 3.8e-07 29.6 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 KFP07464.1 - 4.8e-09 36.2 1.8 0.00039 20.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP07464.1 - 0.00082 18.6 1.3 2 7.9 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 KFP07464.1 - 0.0078 15.9 0.9 0.022 14.4 0.6 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF777 PF05606.6 KFP07464.1 - 0.025 13.7 0.2 0.048 12.8 0.2 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) Toprim PF01751.17 KFP07464.1 - 0.092 12.7 0.1 0.42 10.6 0.0 2.1 3 0 0 3 3 3 0 Toprim domain TPR_11 PF13414.1 KFP07467.1 - 1.6e-34 117.3 7.5 1.6e-08 34.0 0.2 4.8 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFP07467.1 - 6.4e-29 98.3 13.8 1.6e-08 33.7 0.2 7.9 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 KFP07467.1 - 1.5e-27 93.2 7.0 3.1e-06 26.6 0.2 7.7 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFP07467.1 - 9.4e-21 73.9 0.1 2.1e-09 37.8 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFP07467.1 - 4.9e-18 63.4 7.8 1.9e-06 27.2 0.1 7.0 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFP07467.1 - 1.1e-16 60.5 23.8 4.5e-08 32.9 0.8 4.1 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFP07467.1 - 1.9e-15 55.7 0.8 0.46 10.8 0.1 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFP07467.1 - 9.3e-13 47.8 6.9 0.00016 21.4 0.1 4.3 3 1 2 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFP07467.1 - 1.6e-12 47.5 5.8 1.9e-06 28.0 0.8 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFP07467.1 - 6.4e-10 38.7 6.6 0.0022 18.4 0.1 6.4 2 1 3 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP07467.1 - 6.7e-07 29.3 5.8 0.032 14.3 0.6 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFP07467.1 - 0.00012 21.5 5.1 0.0045 16.6 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFP07467.1 - 0.00015 21.9 4.5 0.47 11.0 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFP07467.1 - 0.00028 20.0 7.3 2.3 7.5 0.1 4.6 4 0 0 4 4 4 1 SHNi-TPR NARP1 PF12569.3 KFP07467.1 - 0.00032 19.5 0.5 0.65 8.6 0.1 2.5 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 BTAD PF03704.12 KFP07467.1 - 0.0061 16.8 1.1 0.8 10.0 0.1 2.7 1 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 KFP07467.1 - 0.02 14.8 1.9 0.46 10.4 0.1 3.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 KFP07467.1 - 0.038 13.0 1.0 1.7 7.6 0.0 2.5 1 1 1 3 3 3 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 KFP07467.1 - 0.087 12.6 0.8 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Arv1 PF04161.8 KFP07468.1 - 4.2e-35 121.5 4.3 5.2e-35 121.2 2.9 1.1 1 0 0 1 1 1 1 Arv1-like family SPRY PF00622.23 KFP07469.1 - 5.1e-15 55.6 0.0 9.5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-B_box PF00643.19 KFP07469.1 - 1.1e-09 37.9 3.7 2.9e-09 36.6 2.6 1.8 1 0 0 1 1 1 1 B-box zinc finger fn3 PF00041.16 KFP07469.1 - 1.3e-08 34.8 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PRY PF13765.1 KFP07469.1 - 1.8e-05 24.1 0.1 4.2e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 SPRY-associated domain Laminin_G_3 PF13385.1 KFP07469.1 - 0.00056 20.1 1.2 0.0011 19.2 0.3 1.8 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Barstar PF01337.13 KFP07469.1 - 0.0099 15.6 0.7 0.2 11.5 0.0 2.2 1 1 1 2 2 2 1 Barstar (barnase inhibitor) YlbD_coat PF14071.1 KFP07469.1 - 0.051 13.6 1.9 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Putative coat protein zf-UBR PF02207.15 KFP07469.1 - 0.12 12.0 4.7 1.1 9.0 3.3 2.5 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) IBR PF01485.16 KFP07469.1 - 0.38 10.6 5.9 0.47 10.3 1.5 2.5 2 0 0 2 2 2 0 IBR domain DUF4602 PF15375.1 KFP07470.1 - 5.9e-20 71.7 16.4 6.4e-20 71.5 11.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) Vfa1 PF08432.5 KFP07470.1 - 4.3 7.3 13.3 4.7 7.2 9.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PDCD2_C PF04194.8 KFP07471.1 - 4.3e-50 169.4 1.1 4.9e-50 169.3 0.8 1.0 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain TBP PF00352.16 KFP07472.1 - 2e-65 216.1 0.2 6.3e-32 108.7 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Pollen_allerg_2 PF01620.11 KFP07472.1 - 0.022 15.0 0.6 0.089 13.1 0.0 1.9 1 1 1 2 2 2 0 Ribonuclease (pollen allergen) TFIIA PF03153.8 KFP07472.1 - 1.6 8.5 11.2 1.9 8.2 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Auxin_repressed PF05564.7 KFP07472.1 - 1.8 9.1 6.2 4.2 8.0 4.3 1.7 1 1 0 1 1 1 0 Dormancy/auxin associated protein Proteasome PF00227.21 KFP07473.1 - 1.2e-26 93.1 0.1 1.6e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytochrom_C1 PF02167.10 KFP07473.1 - 0.07 12.7 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C1 family zf-H2C2_2 PF13465.1 KFP07474.1 - 1.1e-49 164.4 55.3 3.9e-10 39.5 0.9 6.9 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFP07474.1 - 1.4e-40 135.1 51.7 3.4e-08 33.3 3.3 7.1 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07474.1 - 6.4e-29 98.1 49.3 6.2e-05 23.0 0.4 7.0 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP07474.1 - 5.7e-24 83.2 30.3 3.8e-05 23.4 0.1 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP07474.1 - 1.7e-18 66.1 19.4 0.0079 16.3 0.0 6.4 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KFP07474.1 - 8.7e-12 44.3 26.1 0.0054 16.3 0.2 6.4 6 0 0 6 6 6 4 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFP07474.1 - 3.8e-11 42.7 15.8 0.086 12.8 0.1 6.1 6 0 0 6 6 6 3 zinc-finger zf-Di19 PF05605.7 KFP07474.1 - 4.8e-10 39.4 19.7 1.7e-05 24.8 0.4 4.8 2 2 3 5 5 4 4 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 KFP07474.1 - 6.2e-10 38.5 2.1 0.02 14.5 0.0 4.2 2 1 2 4 4 4 2 GAGA factor Zn-ribbon_8 PF09723.5 KFP07474.1 - 2.5e-09 36.9 24.5 0.0085 16.0 2.7 5.8 1 1 5 6 6 6 6 Zinc ribbon domain zf-met PF12874.2 KFP07474.1 - 2e-08 34.1 30.2 0.27 11.4 0.2 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type TerY-C PF15616.1 KFP07474.1 - 3.4e-08 33.5 13.2 0.0039 17.1 0.4 3.1 1 1 2 3 3 3 3 TerY-C metal binding domain DZR PF12773.2 KFP07474.1 - 4.7e-08 32.7 16.1 0.024 14.4 0.6 3.6 2 1 1 3 3 3 3 Double zinc ribbon zf-ribbon_3 PF13248.1 KFP07474.1 - 7.7e-08 31.3 26.4 0.26 10.5 0.3 6.2 6 0 0 6 6 6 3 zinc-ribbon domain XPA_N PF01286.13 KFP07474.1 - 9.6e-08 31.5 8.6 0.7 9.6 0.1 6.1 6 0 0 6 6 6 1 XPA protein N-terminal zf-ISL3 PF14690.1 KFP07474.1 - 7.4e-07 29.1 28.9 0.64 10.1 0.3 6.2 6 0 0 6 6 6 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-CHY PF05495.7 KFP07474.1 - 1.1e-06 28.6 16.6 0.00019 21.5 2.3 3.1 1 1 2 3 3 3 2 CHY zinc finger CpXC PF14353.1 KFP07474.1 - 1.2e-06 28.5 15.5 0.33 10.9 0.0 5.9 5 1 0 6 6 6 2 CpXC protein Prok-RING_1 PF14446.1 KFP07474.1 - 4.2e-06 26.3 7.9 9 6.1 0.0 6.1 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 YhfH PF14149.1 KFP07474.1 - 1.8e-05 24.3 15.0 13 5.7 0.0 6.2 6 0 0 6 6 6 0 YhfH-like protein zinc_ribbon_2 PF13240.1 KFP07474.1 - 1.9e-05 24.0 33.6 0.86 9.1 5.1 5.9 5 1 1 6 6 6 3 zinc-ribbon domain FYDLN_acid PF09538.5 KFP07474.1 - 5.5e-05 23.7 12.8 2.8 8.5 0.0 5.2 1 1 3 4 4 4 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.2 KFP07474.1 - 9.8e-05 22.0 32.2 0.13 12.0 3.9 5.0 3 2 2 5 5 5 2 Transposase zinc-ribbon domain DUF164 PF02591.10 KFP07474.1 - 0.00019 21.2 14.6 14 5.6 0.1 6.0 6 0 0 6 6 6 0 Putative zinc ribbon domain zf-BED PF02892.10 KFP07474.1 - 0.0002 21.0 35.4 0.48 10.2 0.6 6.2 4 2 2 6 6 6 3 BED zinc finger DUF329 PF03884.9 KFP07474.1 - 0.00023 20.6 14.9 2.6 7.6 0.1 6.0 6 0 0 6 6 6 0 Domain of unknown function (DUF329) HypA PF01155.14 KFP07474.1 - 0.00028 20.5 11.9 0.49 10.1 0.2 3.6 1 1 3 4 4 4 3 Hydrogenase expression/synthesis hypA family zf-HIT PF04438.11 KFP07474.1 - 0.00032 20.2 25.9 0.68 9.6 0.2 5.9 6 0 0 6 6 6 2 HIT zinc finger zinc_ribbon_5 PF13719.1 KFP07474.1 - 0.00046 19.7 23.5 1.4 8.5 2.1 6.0 5 1 1 6 6 6 1 zinc-ribbon domain zf-CSL PF05207.8 KFP07474.1 - 0.00055 19.3 16.7 0.27 10.7 0.9 4.1 1 1 4 5 5 5 2 CSL zinc finger zf-AN1 PF01428.11 KFP07474.1 - 0.00075 19.3 18.3 5.9 6.8 0.1 6.1 6 0 0 6 6 6 0 AN1-like Zinc finger zf-LYAR PF08790.6 KFP07474.1 - 0.001 18.6 18.9 3.3 7.5 0.2 6.3 7 0 0 7 7 6 0 LYAR-type C2HC zinc finger C1_3 PF07649.7 KFP07474.1 - 0.0014 18.5 14.4 4 7.5 0.0 5.6 6 0 0 6 6 6 0 C1-like domain TFIIS_C PF01096.13 KFP07474.1 - 0.0019 17.7 22.9 4.7 6.9 0.1 6.2 6 0 0 6 6 6 0 Transcription factor S-II (TFIIS) Terminase_GpA PF05876.7 KFP07474.1 - 0.002 16.5 18.4 0.36 9.1 1.6 3.0 1 1 2 3 3 3 3 Phage terminase large subunit (GpA) Evr1_Alr PF04777.8 KFP07474.1 - 0.0026 17.6 16.8 0.038 13.8 0.1 4.8 1 1 3 5 5 5 2 Erv1 / Alr family DUF1610 PF07754.6 KFP07474.1 - 0.0026 17.8 43.3 0.26 11.4 1.1 6.1 6 0 0 6 6 6 3 Domain of unknown function (DUF1610) zinc_ribbon_4 PF13717.1 KFP07474.1 - 0.0034 17.0 24.2 3.5 7.4 2.2 6.0 5 1 1 6 6 6 0 zinc-ribbon domain zf-C4_Topoisom PF01396.14 KFP07474.1 - 0.0038 16.6 11.8 6.8 6.2 0.1 4.8 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger C1_4 PF07975.7 KFP07474.1 - 0.0051 16.7 17.6 4.7 7.3 0.6 5.3 1 1 4 5 5 5 0 TFIIH C1-like domain UPF0547 PF10571.4 KFP07474.1 - 0.014 15.0 33.0 0.61 9.8 0.2 6.2 6 0 0 6 6 6 0 Uncharacterised protein family UPF0547 Sgf11 PF08209.6 KFP07474.1 - 0.017 14.3 15.5 8.8 5.7 0.0 5.9 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) DNA_RNApol_7kD PF03604.8 KFP07474.1 - 0.025 14.0 18.1 11 5.6 0.1 6.1 6 0 0 6 6 6 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_2 PF12756.2 KFP07474.1 - 0.034 14.2 18.8 2.5 8.2 0.1 5.6 1 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) LIM PF00412.17 KFP07474.1 - 0.034 14.2 16.0 8 6.6 0.7 4.8 1 1 3 5 5 5 0 LIM domain zf-IS66 PF13005.2 KFP07474.1 - 0.071 13.0 20.5 4.8 7.2 0.0 5.9 6 0 0 6 6 6 0 zinc-finger binding domain of transposase IS66 cEGF PF12662.2 KFP07474.1 - 0.098 12.3 12.4 0.2 11.3 0.6 3.0 3 0 0 3 3 2 0 Complement Clr-like EGF-like Elf1 PF05129.8 KFP07474.1 - 0.1 12.2 12.5 0.68 9.6 0.2 4.1 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like Cren7 PF11520.3 KFP07474.1 - 0.1 12.2 0.8 17 5.1 0.0 3.6 4 0 0 4 4 3 0 Chromatin protein Cren7 FYVE PF01363.16 KFP07474.1 - 0.12 12.3 21.6 0.8 9.6 0.8 4.7 1 1 2 3 3 3 0 FYVE zinc finger A2L_zn_ribbon PF08792.5 KFP07474.1 - 0.12 11.9 20.2 2.1 7.9 0.2 5.8 6 0 0 6 6 6 0 A2L zinc ribbon domain IBR PF01485.16 KFP07474.1 - 0.14 12.0 20.4 3.2 7.7 1.6 4.8 1 1 2 3 3 3 0 IBR domain OrfB_Zn_ribbon PF07282.6 KFP07474.1 - 0.16 11.6 23.0 2.2 8.0 1.6 5.1 1 1 5 6 6 6 0 Putative transposase DNA-binding domain DUF2225 PF09986.4 KFP07474.1 - 0.19 11.1 13.2 3.3 7.0 0.2 4.6 3 2 2 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Zn_ribbon_recom PF13408.1 KFP07474.1 - 0.34 11.2 26.6 5.9 7.2 1.9 4.8 1 1 4 5 5 5 0 Recombinase zinc beta ribbon domain Rpr2 PF04032.11 KFP07474.1 - 0.39 10.6 12.7 1.5 8.7 0.9 3.3 2 2 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Mss51 PF13824.1 KFP07474.1 - 0.42 10.4 32.9 3.9 7.4 3.3 5.8 2 2 2 4 4 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Rad50_zn_hook PF04423.9 KFP07474.1 - 0.53 9.7 11.9 11 5.5 0.3 4.3 3 1 1 4 4 4 0 Rad50 zinc hook motif ARS2 PF04959.8 KFP07474.1 - 0.55 10.3 8.0 15 5.6 0.0 3.5 1 1 3 4 4 3 0 Arsenite-resistance protein 2 NMD3 PF04981.8 KFP07474.1 - 0.65 9.0 10.0 35 3.3 0.1 3.3 1 1 1 2 2 2 0 NMD3 family PHD PF00628.24 KFP07474.1 - 0.74 9.5 18.9 3.9 7.2 1.1 4.2 4 0 0 4 4 4 0 PHD-finger Mut7-C PF01927.11 KFP07474.1 - 1.1 9.2 18.8 6.4 6.7 1.4 5.0 1 1 4 5 5 5 0 Mut7-C RNAse domain DUF1247 PF06851.6 KFP07474.1 - 1.3 8.6 3.9 10 5.7 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1247) zf-trcl PF13451.1 KFP07474.1 - 2.1 8.0 17.8 9.2 5.9 1.8 5.5 4 2 1 5 5 5 0 Probable zinc-binding domain Ogr_Delta PF04606.7 KFP07474.1 - 2.2 8.0 28.2 0.12 11.9 1.7 5.0 1 1 4 5 5 5 0 Ogr/Delta-like zinc finger Rubredoxin PF00301.15 KFP07474.1 - 2.9 7.8 23.5 13 5.7 2.1 4.9 4 2 0 4 4 4 0 Rubredoxin RRN7 PF11781.3 KFP07474.1 - 5.2 6.6 16.9 16 5.1 0.0 5.4 6 0 0 6 6 5 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-FPG_IleRS PF06827.9 KFP07474.1 - 5.9 6.6 19.0 46 3.7 0.1 6.0 6 0 0 6 6 6 0 Zinc finger found in FPG and IleRS Cys_rich_CPXG PF14255.1 KFP07474.1 - 8 6.3 19.6 62 3.5 0.0 5.9 6 0 0 6 6 6 0 Cysteine-rich CPXCG Lar_restr_allev PF14354.1 KFP07474.1 - 8.6 6.7 27.9 55 4.1 3.4 4.9 2 2 1 3 3 3 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.1 KFP07474.1 - 8.7 6.1 23.5 39 4.0 0.3 6.1 6 0 0 6 6 6 0 Nudix N-terminal VWD PF00094.20 KFP07475.1 - 0.0002 21.5 0.2 0.00028 21.1 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type D domain VWD PF00094.20 KFP07476.1 - 3.1e-07 30.6 0.0 3.4e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type D domain zf-H2C2_2 PF13465.1 KFP07477.1 - 1.6e-23 81.7 10.9 1.2e-08 34.7 0.2 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFP07477.1 - 2.5e-13 49.5 22.2 1.7e-06 28.0 0.5 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07477.1 - 6.9e-09 35.4 23.4 8.5e-05 22.6 0.5 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP07477.1 - 9.9e-08 31.6 12.1 0.011 15.5 0.3 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP07477.1 - 0.00071 19.6 7.0 0.11 12.6 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.7 KFP07477.1 - 0.0055 16.8 3.4 0.0079 16.3 2.3 1.3 1 0 0 1 1 1 1 CHY zinc finger Prok-RING_1 PF14446.1 KFP07477.1 - 0.0055 16.4 1.3 0.9 9.3 0.0 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 RRN7 PF11781.3 KFP07477.1 - 0.0089 15.5 3.9 0.053 13.0 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase I-specific transcription initiation factor Rrn7 C1_1 PF00130.17 KFP07477.1 - 0.0094 15.6 3.1 0.12 12.0 0.2 2.2 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-met PF12874.2 KFP07477.1 - 0.01 16.0 7.0 0.028 14.6 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP07477.1 - 0.013 15.6 9.8 0.099 12.7 1.6 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KFP07477.1 - 0.04 13.5 1.2 0.04 13.5 0.8 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFP07477.1 - 0.052 13.5 6.3 4.7 7.2 0.0 3.1 3 0 0 3 3 3 0 zinc-finger LIM PF00412.17 KFP07477.1 - 0.064 13.3 7.3 4.2 7.5 0.1 2.6 2 1 0 2 2 2 0 LIM domain zf-LYAR PF08790.6 KFP07477.1 - 0.079 12.6 8.0 0.19 11.4 0.1 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-AN1 PF01428.11 KFP07477.1 - 0.09 12.6 6.7 3.2 7.7 0.1 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger DZR PF12773.2 KFP07477.1 - 0.12 12.2 7.9 0.11 12.3 0.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.14 KFP07477.1 - 0.12 12.0 4.3 0.57 9.8 3.0 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_2 PF12756.2 KFP07477.1 - 0.16 12.0 4.7 2.7 8.1 0.1 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 KFP07477.1 - 0.17 11.8 8.9 2.5 8.1 3.9 2.9 2 1 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 KFP07477.1 - 0.22 11.2 5.2 0.059 13.0 0.7 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like FYDLN_acid PF09538.5 KFP07477.1 - 0.22 12.1 2.0 9.4 6.8 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) C1_4 PF07975.7 KFP07477.1 - 0.29 11.1 6.1 3 7.9 4.2 2.1 1 1 0 1 1 1 0 TFIIH C1-like domain YhfH PF14149.1 KFP07477.1 - 0.31 10.8 2.2 3.6 7.4 0.1 2.6 3 0 0 3 3 3 0 YhfH-like protein Endonuclease_7 PF02945.10 KFP07477.1 - 0.43 10.3 3.8 1.6 8.4 0.4 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII zf-TRAF PF02176.13 KFP07477.1 - 0.48 10.8 5.1 1.6 9.1 2.0 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger C1_3 PF07649.7 KFP07477.1 - 0.57 10.2 3.6 20 5.2 0.1 3.1 3 0 0 3 3 3 0 C1-like domain PHD PF00628.24 KFP07477.1 - 0.65 9.7 5.0 4.9 6.9 3.7 2.1 1 1 1 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 KFP07477.1 - 1.1 9.0 9.5 1.7 8.5 3.0 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 KFP07477.1 - 1.7 8.9 4.1 2.5 8.4 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-BED PF02892.10 KFP07477.1 - 2 8.2 6.0 16 5.3 1.1 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C3HC4_3 PF13920.1 KFP07477.1 - 2 8.1 5.9 18 5.1 4.2 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CpXC PF14353.1 KFP07477.1 - 2.1 8.2 7.1 2.7 7.9 0.1 2.8 2 1 0 2 2 2 0 CpXC protein DUF2256 PF10013.4 KFP07477.1 - 2.2 8.0 7.6 27 4.6 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.9 KFP07477.1 - 2.4 7.9 7.3 3.3 7.4 1.3 3.1 2 1 0 2 2 2 0 Adenylate kinase, active site lid GAGA PF09237.6 KFP07477.1 - 3.1 7.4 9.1 0.58 9.7 0.1 2.6 1 1 2 3 3 3 0 GAGA factor HNH PF01844.18 KFP07477.1 - 3.7 7.4 7.9 5.9 6.8 0.0 2.7 3 0 0 3 3 2 0 HNH endonuclease zf-ISL3 PF14690.1 KFP07477.1 - 5.3 7.1 10.7 5.7 7.0 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-RING_2 PF13639.1 KFP07477.1 - 6.4 6.6 8.1 34 4.3 5.6 2.3 1 1 0 1 1 1 0 Ring finger domain IBR PF01485.16 KFP07477.1 - 8.4 6.3 7.7 29 4.6 0.2 3.0 2 1 1 3 3 3 0 IBR domain TRAPPC9-Trs120 PF08626.6 KFP07478.1 - 2.5e-241 803.5 0.0 5.3e-241 802.4 0.0 1.5 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit AF1Q PF15017.1 KFP07479.1 - 0.0028 17.5 2.4 0.0032 17.3 1.7 1.1 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator RNA_pol_3_Rpc31 PF11705.3 KFP07479.1 - 0.022 14.7 7.1 0.024 14.5 4.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4611 PF15387.1 KFP07479.1 - 0.047 13.8 2.7 0.047 13.8 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 KFP07479.1 - 0.05 13.1 5.9 0.05 13.1 4.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 KFP07479.1 - 0.18 11.6 2.4 0.21 11.4 1.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1187 PF06688.6 KFP07479.1 - 0.27 11.3 1.2 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) Mak16 PF04874.9 KFP07479.1 - 0.41 10.7 10.7 0.58 10.2 7.4 1.4 1 1 0 1 1 1 0 Mak16 protein C-terminal region DUF2457 PF10446.4 KFP07479.1 - 0.9 8.2 8.5 0.86 8.2 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase_Tyr PF07714.12 KFP07480.1 - 2.5e-93 311.8 0.0 4.1e-93 311.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP07480.1 - 6e-47 159.9 0.0 1.3e-46 158.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Focal_AT PF03623.8 KFP07480.1 - 2e-45 153.6 1.2 4.7e-45 152.4 0.9 1.6 1 0 0 1 1 1 1 Focal adhesion targeting region FERM_M PF00373.13 KFP07480.1 - 5.3e-11 42.7 0.1 5.3e-11 42.7 0.1 2.7 3 1 0 3 3 3 1 FERM central domain Kinase-like PF14531.1 KFP07480.1 - 6.8e-05 21.9 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FERM_N PF09379.5 KFP07480.1 - 0.076 13.0 0.1 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 FERM N-terminal domain DUF4085 PF13315.1 KFP07480.1 - 0.86 8.9 7.9 1.3 8.3 0.2 3.0 3 1 0 4 4 4 0 Protein of unknown function (DUF4085) uDENN PF03456.13 KFP07481.1 - 2e-06 27.6 0.0 4.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFP07482.1 - 1.6e-08 34.4 0.4 4.2e-08 33.1 0.3 1.8 1 0 0 1 1 1 1 dDENN domain bPH_3 PF14470.1 KFP07482.1 - 0.09 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain MFS_2 PF13347.1 KFP07483.1 - 3.4e-07 29.0 0.8 3.4e-07 29.0 0.6 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein 7tm_1 PF00001.16 KFP07484.1 - 5.5e-34 117.4 31.8 1.2e-33 116.3 22.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) YWFCY PF14293.1 KFP07484.1 - 1.3 8.8 7.7 8.4 6.3 0.4 3.2 3 0 0 3 3 3 0 YWFCY protein DUF3481 PF11980.3 KFP07484.1 - 3 7.7 8.2 0.11 12.3 0.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) DUF1469 PF07332.6 KFP07484.1 - 5 6.8 6.1 2.6 7.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Y_phosphatase PF00102.22 KFP07486.1 - 7.1e-11 41.8 0.0 5.3e-09 35.7 0.0 2.0 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KFP07486.1 - 1.7e-09 37.3 0.0 2.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RVT_1 PF00078.22 KFP07492.1 - 2.8e-19 69.3 0.0 4.1e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KFP07492.1 - 3.1e-07 29.8 0.1 6.2e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Brix PF04427.13 KFP07493.1 - 1.4e-17 64.0 0.5 1.5e-17 63.8 0.4 1.1 1 0 0 1 1 1 1 Brix domain adh_short PF00106.20 KFP07494.1 - 1.7e-25 89.8 0.0 2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFP07494.1 - 2.8e-09 37.1 0.0 3.4e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFP07494.1 - 7.1e-06 25.7 0.0 8.3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFP07494.1 - 0.00077 18.6 0.0 0.0009 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CHAP PF05257.11 KFP07494.1 - 0.26 10.9 0.8 5.3 6.7 0.1 2.1 1 1 1 2 2 2 0 CHAP domain ADP_PFK_GK PF04587.10 KFP07495.1 - 4.6e-119 397.5 0.0 5.3e-119 397.3 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Neogenin_C PF06583.7 KFP07496.1 - 6e-115 384.1 26.6 9.4e-115 383.5 18.4 1.3 1 0 0 1 1 1 1 Neogenin C-terminus fn3 PF00041.16 KFP07496.1 - 5.2e-85 279.6 28.8 2.1e-18 66.2 0.1 6.5 6 0 0 6 6 6 6 Fibronectin type III domain I-set PF07679.11 KFP07496.1 - 8.8e-54 179.3 0.2 3.3e-16 58.8 0.0 6.7 7 0 0 7 7 7 5 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP07496.1 - 1.5e-34 117.9 0.0 2.5e-08 33.9 0.0 5.3 5 0 0 5 5 5 4 Immunoglobulin domain Ig_3 PF13927.1 KFP07496.1 - 2e-23 82.6 6.2 1.5e-06 28.5 0.0 6.8 7 0 0 7 7 5 4 Immunoglobulin domain ig PF00047.20 KFP07496.1 - 1.3e-21 76.4 0.8 0.00014 21.9 0.0 6.4 5 1 0 5 5 5 3 Immunoglobulin domain V-set PF07686.12 KFP07496.1 - 1.5e-17 63.5 0.3 6.5e-06 26.0 0.0 6.8 6 2 0 6 6 6 3 Immunoglobulin V-set domain Interfer-bind PF09294.5 KFP07496.1 - 2.5e-15 56.3 0.2 0.042 13.8 0.0 5.9 6 0 0 6 6 6 4 Interferon-alpha/beta receptor, fibronectin type III Tissue_fac PF01108.12 KFP07496.1 - 1.9e-07 30.7 4.3 0.0055 16.4 0.0 5.2 5 1 1 6 6 6 2 Tissue factor C2-set_2 PF08205.7 KFP07496.1 - 1.5e-06 27.9 0.0 2 8.3 0.0 4.0 3 0 0 3 3 3 3 CD80-like C2-set immunoglobulin domain EphA2_TM PF14575.1 KFP07496.1 - 4.6e-05 23.7 0.8 0.0001 22.6 0.5 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SusE PF14292.1 KFP07496.1 - 0.036 13.8 0.0 2.7 7.8 0.0 3.5 4 0 0 4 4 4 0 SusE outer membrane protein Ly49 PF08391.5 KFP07496.1 - 0.05 13.7 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region TMEM154 PF15102.1 KFP07496.1 - 0.085 12.5 1.5 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family Shisa PF13908.1 KFP07496.1 - 0.097 12.8 0.1 0.097 12.8 0.0 3.2 4 0 0 4 4 2 0 Wnt and FGF inhibitory regulator V-set_CD47 PF08204.6 KFP07496.1 - 0.41 10.4 2.0 2.8 7.7 0.0 3.3 4 1 0 4 4 3 0 CD47 immunoglobulin-like domain P12 PF12669.2 KFP07496.1 - 0.46 10.7 0.8 0.94 9.7 0.6 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF2659 PF10858.3 KFP07496.1 - 0.53 9.6 0.3 0.93 8.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) NHR2 PF08788.6 KFP07497.1 - 2.8e-39 132.4 8.6 8.5e-39 130.9 6.0 1.9 1 0 0 1 1 1 1 NHR2 domain like TAFH PF07531.9 KFP07497.1 - 6.1e-35 118.7 0.9 1.2e-34 117.8 0.6 1.5 1 0 0 1 1 1 1 NHR1 homology to TAF zf-MYND PF01753.13 KFP07497.1 - 8.6e-08 31.9 18.4 8.6e-08 31.9 12.7 2.0 2 0 0 2 2 2 1 MYND finger DUF3731 PF12531.3 KFP07497.1 - 0.11 11.9 4.5 0.041 13.4 1.1 1.7 2 0 0 2 2 2 0 DNA-K related protein vATP-synt_E PF01991.13 KFP07497.1 - 0.61 9.3 12.3 1 8.6 8.6 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ATP-synt_B PF00430.13 KFP07497.1 - 8.7 6.1 13.0 18 5.1 9.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Yae1_N PF09811.4 KFP07498.1 - 5.4e-16 57.8 46.2 1.5e+04 -6.7 32.0 4.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DDE_1 PF03184.14 KFP07499.1 - 1.3e-20 73.4 0.0 4.2e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease TRIQK PF15168.1 KFP07500.1 - 4.2e-28 97.0 0.4 4.6e-28 96.9 0.3 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family TctB PF07331.6 KFP07500.1 - 0.046 13.3 0.2 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family CoxIIa PF08113.6 KFP07500.1 - 0.17 11.6 2.1 0.22 11.2 1.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family FAM92 PF06730.6 KFP07501.1 - 4.8e-109 362.8 11.0 6.1e-109 362.4 7.6 1.0 1 0 0 1 1 1 1 FAM92 protein BAR PF03114.13 KFP07501.1 - 8.5e-05 22.1 5.8 0.00014 21.4 3.7 1.4 1 1 0 1 1 1 1 BAR domain Vps5 PF09325.5 KFP07501.1 - 0.0018 17.5 6.7 0.098 11.8 4.6 2.9 1 1 0 1 1 1 1 Vps5 C terminal like P4Ha_N PF08336.6 KFP07501.1 - 0.0056 16.4 1.2 0.0056 16.4 0.8 2.0 1 1 1 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HAUS-augmin3 PF14932.1 KFP07501.1 - 0.26 10.4 8.5 0.051 12.7 3.0 1.9 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 RRM_6 PF14259.1 KFP07502.1 - 1.5e-37 127.3 0.3 7e-11 41.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP07502.1 - 3.4e-24 84.2 0.1 1.3e-06 27.8 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07502.1 - 1.5e-09 37.5 0.0 0.092 12.6 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Meckelin PF09773.4 KFP07503.1 - 2.8e-299 994.7 14.4 3.7e-299 994.3 10.0 1.1 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) PP2C PF00481.16 KFP07504.1 - 6.7e-36 123.9 0.0 6.3e-35 120.7 0.0 2.1 1 1 0 2 2 2 1 Protein phosphatase 2C Rod_C PF10493.4 KFP07504.1 - 0.019 13.3 0.0 0.026 12.8 0.0 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region AF0941-like PF14591.1 KFP07504.1 - 0.13 12.3 0.0 3.6 7.6 0.0 2.8 3 0 0 3 3 3 0 AF0941-like Ras PF00071.17 KFP07505.1 - 5.9e-31 107.0 0.1 1.8e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFP07505.1 - 1.1e-19 71.0 0.0 2.6e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 KFP07505.1 - 3.2e-05 23.2 0.0 0.00014 21.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KFP07505.1 - 0.0006 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFP07505.1 - 0.029 14.3 0.2 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KFP07505.1 - 0.032 14.5 0.0 0.062 13.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 KFP07505.1 - 0.039 13.7 2.5 0.043 13.6 0.1 2.2 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.1 KFP07505.1 - 0.098 12.7 0.2 18 5.4 0.0 3.0 1 1 1 2 2 2 0 AAA domain Myb_DNA-bind_5 PF13873.1 KFP07506.1 - 3.4e-20 71.7 5.0 4.1e-20 71.4 0.0 2.9 3 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain DUF1041 PF06292.12 KFP07506.1 - 0.0052 16.9 2.9 0.044 13.9 0.1 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1041) Myb_DNA-bind_4 PF13837.1 KFP07506.1 - 0.0061 16.6 0.2 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain zf-TRAF PF02176.13 KFP07507.1 - 1.2e-08 35.2 3.7 1.2e-08 35.2 2.6 3.2 2 1 1 3 3 2 2 TRAF-type zinc finger zf-C3HC4 PF00097.20 KFP07507.1 - 1e-07 31.5 7.5 1e-07 31.5 5.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP07507.1 - 3e-07 30.1 8.2 3e-07 30.1 5.7 2.6 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFP07507.1 - 9.8e-07 28.5 6.1 9.8e-07 28.5 4.3 2.7 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING Sina PF03145.11 KFP07507.1 - 4.4e-06 26.4 10.0 6.7e-05 22.6 3.0 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-C3HC4_2 PF13923.1 KFP07507.1 - 1.6e-05 24.8 7.6 1.6e-05 24.8 5.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP07507.1 - 2.9e-05 23.6 3.2 2.9e-05 23.6 2.2 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFP07507.1 - 0.00015 21.4 1.9 0.00052 19.7 1.3 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KFP07507.1 - 0.0013 18.3 5.6 0.0013 18.3 3.9 2.5 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFP07507.1 - 0.0017 18.0 5.2 0.0043 16.7 3.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DM PF00751.13 KFP07507.1 - 6.1 6.4 16.3 0.8 9.2 2.4 3.4 2 1 1 3 3 3 0 DM DNA binding domain RRM_6 PF14259.1 KFP07509.1 - 2.5e-48 161.9 0.0 9.9e-16 57.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP07509.1 - 4e-16 58.4 0.0 0.00036 20.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07509.1 - 3.4e-06 26.8 0.2 0.27 11.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4283 PF14111.1 KFP07509.1 - 0.0013 17.8 0.1 0.047 12.7 0.0 3.4 4 1 1 5 5 5 1 Domain of unknown function (DUF4283) Dpy19 PF10034.4 KFP07510.1 - 1.4e-197 657.8 30.0 1.6e-197 657.6 20.8 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Cadherin PF00028.12 KFP07511.1 - 5.5e-212 686.8 25.3 1.8e-20 73.0 0.0 15.4 15 0 0 15 15 15 15 Cadherin domain Cadherin_C PF01049.12 KFP07511.1 - 4.1e-38 130.7 0.2 1e-37 129.4 0.1 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region Laminin_G_2 PF02210.19 KFP07511.1 - 2.8e-37 127.6 1.4 4.5e-21 75.2 0.0 2.9 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFP07511.1 - 2.2e-26 92.3 0.1 4.7e-12 46.0 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain Cadherin_pro PF08758.6 KFP07511.1 - 2.9e-12 46.2 0.1 4.9e-05 23.0 0.0 8.0 9 0 0 9 9 9 1 Cadherin prodomain like EGF PF00008.22 KFP07511.1 - 1.1e-10 41.2 45.5 0.00022 21.0 5.8 5.0 4 0 0 4 4 4 4 EGF-like domain Cadherin_2 PF08266.7 KFP07511.1 - 1.5e-06 27.7 0.0 1 8.9 0.0 6.1 6 0 0 6 6 6 1 Cadherin-like Y_Y_Y PF07495.8 KFP07511.1 - 1.5e-06 27.8 1.9 0.11 12.2 0.0 5.3 4 0 0 4 4 4 2 Y_Y_Y domain EGF_2 PF07974.8 KFP07511.1 - 0.025 14.7 63.8 0.021 14.9 7.4 4.4 4 0 0 4 4 3 0 EGF-like domain Big_3_4 PF13754.1 KFP07511.1 - 0.064 13.5 0.0 0.064 13.5 0.0 8.2 11 0 0 11 11 11 0 Bacterial Ig-like domain (group 3) He_PIG PF05345.7 KFP07511.1 - 0.24 11.4 15.8 0.19 11.7 0.2 5.7 6 0 0 6 6 6 0 Putative Ig domain TPR_2 PF07719.12 KFP07512.1 - 0.00076 19.2 5.2 0.23 11.4 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP07512.1 - 0.0017 18.0 0.6 0.18 11.6 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP07512.1 - 0.0089 15.7 1.4 3.4 7.6 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP07512.1 - 0.19 11.4 9.0 2.6 7.8 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Cyclin_N PF00134.18 KFP07513.1 - 4.5e-40 136.1 1.3 9.5e-40 135.0 0.9 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP07513.1 - 3.3e-12 46.3 0.1 7.6e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DOR PF14839.1 KFP07514.1 - 2.4e-80 269.3 0.5 2.7e-80 269.1 0.3 1.0 1 0 0 1 1 1 1 DOR family SQS_PSY PF00494.14 KFP07515.1 - 2.3e-52 177.9 0.3 2.8e-52 177.6 0.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase FYVE PF01363.16 KFP07516.1 - 7.9e-20 70.5 7.6 1.9e-19 69.2 5.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 KFP07516.1 - 4.7e-12 46.0 0.1 9.6e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 KFP07516.1 - 0.0006 19.6 5.1 0.0011 18.8 3.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-DHHC PF01529.15 KFP07516.1 - 0.041 13.2 2.2 0.069 12.5 1.5 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase PH_11 PF15413.1 KFP07516.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain IBR PF01485.16 KFP07516.1 - 0.12 12.2 4.8 0.32 10.8 3.3 1.8 1 0 0 1 1 1 0 IBR domain zf-UDP PF14569.1 KFP07516.1 - 3.2 7.5 9.6 5.4 6.8 2.3 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger DZR PF12773.2 KFP07516.1 - 3.7 7.4 11.1 15 5.4 4.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon RMP PF14996.1 KFP07517.1 - 8.6e-47 158.7 5.9 9.4e-47 158.5 4.1 1.0 1 0 0 1 1 1 1 Retinal Maintenance Allantoicase PF03561.10 KFP07517.1 - 0.036 13.5 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Allantoicase repeat UCR_14kD PF02271.11 KFP07518.1 - 3.9e-31 106.9 3.6 4.3e-31 106.7 2.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit mTERF PF02536.9 KFP07519.1 - 7.1e-25 87.3 1.0 2.3e-13 49.4 0.1 2.2 1 1 1 2 2 2 2 mTERF PSS PF03034.10 KFP07520.1 - 9.8e-109 363.0 22.9 9.8e-109 363.0 15.8 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase Peptidase_C1 PF00112.18 KFP07520.1 - 0.049 13.5 0.1 0.088 12.6 0.1 1.3 1 0 0 1 1 1 0 Papain family cysteine protease DUF2393 PF09624.5 KFP07520.1 - 0.26 10.8 2.7 1.1 8.7 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) DUF2207 PF09972.4 KFP07520.1 - 2.1 6.8 5.7 7 5.1 1.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Syndecan PF01034.15 KFP07521.1 - 2e-33 113.8 0.0 3.4e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Protocadherin PF08374.6 KFP07521.1 - 0.025 14.2 3.0 0.12 11.9 0.0 2.2 1 1 1 2 2 2 0 Protocadherin Glycophorin_A PF01102.13 KFP07521.1 - 0.032 14.0 8.8 0.13 11.9 0.3 2.2 1 1 1 2 2 2 0 Glycophorin A Herpes_gE PF02480.11 KFP07521.1 - 0.037 12.2 0.0 0.071 11.3 0.0 1.5 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Plasmodium_Vir PF05795.6 KFP07521.1 - 0.1 11.8 0.2 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2407_C PF13373.1 KFP07521.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain MtrF PF09472.5 KFP07521.1 - 0.57 9.4 2.6 0.85 8.8 1.8 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TGF_beta_GS PF08515.7 KFP07521.1 - 2.5 7.5 4.8 0.6 9.4 0.9 1.8 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif PA PF02225.17 KFP07522.1 - 1.7e-05 24.3 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PA domain F420_oxidored PF03807.12 KFP07522.1 - 0.089 13.2 0.6 2.2 8.7 0.0 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HisG PF01634.13 KFP07522.1 - 0.097 12.2 0.1 1.1 8.8 0.0 2.4 3 0 0 3 3 3 0 ATP phosphoribosyltransferase Peptidase_M28 PF04389.12 KFP07523.1 - 1.4e-19 70.5 0.0 1.7e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFP07523.1 - 1.1e-06 28.3 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Mtp PF03821.11 KFP07524.1 - 3.4e-23 82.2 11.9 4e-23 82.0 8.2 1.0 1 0 0 1 1 1 1 Golgi 4-transmembrane spanning transporter Tetraspannin PF00335.15 KFP07524.1 - 0.11 11.7 13.0 0.094 11.9 1.6 2.2 1 1 1 2 2 2 0 Tetraspanin family DUF2244 PF10003.4 KFP07524.1 - 2.6 7.4 4.6 33 3.8 0.0 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3139 PF11337.3 KFP07524.1 - 3.9 7.8 5.1 2.6 8.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DUF3112 PF11309.3 KFP07524.1 - 7.2 6.3 11.8 15 5.3 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) VWA PF00092.23 KFP07525.1 - 2.6e-99 330.2 0.3 1.1e-48 165.2 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain FXa_inhibition PF14670.1 KFP07525.1 - 2.2e-88 290.0 155.7 1.4e-10 41.0 5.0 10.8 11 0 0 11 11 11 10 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP07525.1 - 3.9e-50 167.0 78.1 2.9e-06 26.8 1.9 10.9 10 1 0 10 10 10 10 Complement Clr-like EGF-like EGF_CA PF07645.10 KFP07525.1 - 7.3e-45 150.7 140.2 2.8e-06 27.2 4.8 10.5 10 0 0 10 10 10 10 Calcium-binding EGF domain EGF PF00008.22 KFP07525.1 - 2.3e-31 107.3 128.0 0.00052 19.9 4.5 11.0 11 0 0 11 11 11 10 EGF-like domain VWA_2 PF13519.1 KFP07525.1 - 5.8e-27 94.8 0.0 3.3e-13 50.0 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain EGF_3 PF12947.2 KFP07525.1 - 1.4e-14 53.7 148.6 0.0043 16.9 3.2 11.3 11 0 0 11 11 11 10 EGF domain Matrilin_ccoil PF10393.4 KFP07525.1 - 9.3e-08 31.3 0.9 9.3e-08 31.3 0.7 2.4 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin vWA-TerF-like PF10138.4 KFP07525.1 - 3.2e-07 30.3 0.1 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 2 vWA found in TerF C terminus Ribosomal_L7Ae PF01248.21 KFP07526.1 - 4.7e-09 35.6 0.0 5.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribonuc_L-PSP PF01042.16 KFP07527.1 - 4.6e-39 132.9 0.2 5.1e-39 132.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF3494 PF11999.3 KFP07527.1 - 0.043 13.4 0.2 0.048 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) POP1 PF06978.6 KFP07528.1 - 1.3e-42 145.5 22.6 4.2e-25 88.5 2.7 3.3 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KFP07528.1 - 7.6e-30 102.6 0.2 7.6e-30 102.6 0.1 2.6 3 0 0 3 3 3 1 POPLD (NUC188) domain EF-hand_3 PF09069.6 KFP07528.1 - 0.0042 17.1 0.0 0.37 10.8 0.0 2.9 2 0 0 2 2 2 1 EF-hand AAA_11 PF13086.1 KFP07528.1 - 0.68 9.4 6.6 1.8 8.0 1.6 2.4 2 0 0 2 2 2 0 AAA domain Mg_trans_NIPA PF05653.9 KFP07529.1 - 2.7e-88 295.7 23.5 3.1e-88 295.6 16.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KFP07529.1 - 0.00083 19.3 3.4 0.00083 19.3 2.4 3.1 2 2 1 3 3 3 1 EamA-like transporter family DUF872 PF05915.7 KFP07529.1 - 0.66 9.8 0.1 0.66 9.8 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) BTB_2 PF02214.17 KFP07530.1 - 8.6e-32 109.2 0.3 1.6e-30 105.1 0.1 2.5 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.26 KFP07530.1 - 4.6e-27 94.5 13.2 6e-27 94.2 4.1 2.5 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.11 KFP07530.1 - 8e-13 47.9 3.7 8e-13 47.9 2.6 2.0 2 0 0 2 2 2 1 Ion channel Col_cuticle_N PF01484.12 KFP07530.1 - 9.3 6.0 13.7 8.2 6.2 0.0 3.4 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.20 KFP07531.1 - 5.2e-71 238.8 0.0 8.7e-71 238.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07531.1 - 4.2e-53 180.0 1.7 8e-53 179.1 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Mst1_SARAH PF11629.3 KFP07531.1 - 4.3e-27 93.6 3.6 1.5e-26 91.9 2.5 2.0 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Kinase-like PF14531.1 KFP07531.1 - 0.02 13.8 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Kinase-like NAP PF00956.13 KFP07531.1 - 1.8 7.5 12.1 0.089 11.9 0.4 2.8 3 0 0 3 3 3 0 Nucleosome assembly protein (NAP) Aldedh PF00171.17 KFP07532.1 - 6.2e-167 555.6 1.8 7e-167 555.4 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family REJ PF02010.10 KFP07533.1 - 1.9e-21 75.9 11.3 2e-11 42.8 0.3 3.3 1 1 2 3 3 3 3 REJ domain Y_Y_Y PF07495.8 KFP07533.1 - 2.6e-16 59.1 0.0 0.0018 17.9 0.0 5.3 5 0 0 5 5 5 4 Y_Y_Y domain PKD PF00801.15 KFP07533.1 - 4.1e-13 48.8 7.9 0.03 14.0 0.3 5.7 5 0 0 5 5 5 4 PKD domain DUF4625 PF15418.1 KFP07533.1 - 2e-09 37.6 0.0 0.46 10.5 0.0 4.5 4 0 0 4 4 4 3 Domain of unknown function (DUF4625) He_PIG PF05345.7 KFP07533.1 - 1.8e-06 27.8 3.2 2.7 8.0 0.0 5.6 5 0 0 5 5 5 2 Putative Ig domain Big_3_4 PF13754.1 KFP07533.1 - 3.8e-06 27.1 10.3 0.49 10.7 0.3 5.2 5 0 0 5 5 5 3 Bacterial Ig-like domain (group 3) MANEC PF07502.9 KFP07533.1 - 0.0062 16.5 7.7 0.021 14.7 5.3 1.9 1 0 0 1 1 1 1 MANEC domain SieB PF14163.1 KFP07533.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B zf-H2C2_2 PF13465.1 KFP07534.1 - 6.1e-32 108.3 61.5 4e-08 33.1 0.7 11.7 12 0 0 12 12 12 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFP07534.1 - 3.8e-30 102.3 74.1 0.00011 22.3 0.1 10.4 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07534.1 - 1.5e-26 90.6 66.1 0.00011 22.2 0.4 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP07534.1 - 7.5e-22 76.8 45.3 0.0012 18.9 0.9 9.8 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP07534.1 - 6.3e-20 70.6 59.7 0.0022 18.1 0.3 9.8 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFP07534.1 - 0.063 13.3 44.5 0.25 11.4 1.2 8.8 4 4 5 9 9 9 0 C2H2 type zinc-finger (2 copies) BolA PF01722.13 KFP07534.1 - 0.17 11.8 2.4 32 4.5 0.1 3.6 3 0 0 3 3 3 0 BolA-like protein DUF2225 PF09986.4 KFP07534.1 - 0.35 10.3 0.0 0.35 10.3 0.0 2.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) Elf1 PF05129.8 KFP07534.1 - 1.4 8.6 28.8 1.1 9.0 0.2 5.6 4 1 1 5 5 5 0 Transcription elongation factor Elf1 like E1-E2_ATPase PF00122.15 KFP07535.1 - 1.2e-24 86.5 0.0 2.5e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFP07535.1 - 5.6e-16 59.6 0.0 1.3e-15 58.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFP07535.1 - 6.1e-14 52.6 0.0 4.4e-13 49.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFP07535.1 - 2.7e-06 27.2 0.0 1.3e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFP07535.1 - 0.00037 20.1 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF443 PF04276.7 KFP07535.1 - 0.022 14.2 0.3 0.022 14.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF443) DUF4174 PF13778.1 KFP07535.1 - 0.074 13.1 0.2 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) RHD PF00554.17 KFP07536.1 - 1.5e-25 89.8 0.1 5.5e-25 88.0 0.1 2.0 1 1 0 1 1 1 1 Rel homology domain (RHD) TIG PF01833.19 KFP07536.1 - 9.8e-07 28.6 0.0 5e-06 26.4 0.0 2.4 1 0 0 1 1 1 1 IPT/TIG domain Ion_trans PF00520.26 KFP07537.1 - 3.2e-30 104.9 1.9 1.5e-28 99.4 1.8 2.1 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP07537.1 - 1.4e-28 98.9 0.0 2.9e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP07537.1 - 5.8e-14 51.5 4.6 1.1e-13 50.6 1.1 2.4 2 0 0 2 2 2 1 Ion channel DUF979 PF06166.7 KFP07537.1 - 0.081 11.8 0.3 0.35 9.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF979) PQ-loop PF04193.9 KFP07538.1 - 3.3e-30 103.3 1.5 1.3e-19 69.4 0.0 3.8 3 1 1 4 4 4 2 PQ loop repeat MtN3_slv PF03083.11 KFP07538.1 - 0.0046 16.7 10.2 0.0047 16.7 0.5 2.6 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange DIM1 PF02966.11 KFP07539.1 - 6.8e-65 216.5 1.3 7.6e-65 216.4 0.9 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KFP07539.1 - 1.1e-05 25.0 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KFP07539.1 - 0.0048 16.8 0.1 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KFP07539.1 - 0.022 14.8 0.4 0.036 14.1 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 KFP07539.1 - 0.061 13.5 0.2 0.082 13.1 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain 2-Hacid_dh_C PF02826.14 KFP07540.1 - 6.8e-60 201.2 0.0 1.1e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFP07540.1 - 3.4e-19 68.6 0.0 3.8e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFP07540.1 - 6.4e-09 35.8 0.1 1.1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KFP07540.1 - 0.0018 18.1 0.0 0.26 11.1 0.0 2.4 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 KFP07540.1 - 0.0042 17.0 0.2 0.054 13.5 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain IlvN PF07991.7 KFP07540.1 - 0.0066 15.8 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 KFP07540.1 - 0.12 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Homeobox PF00046.24 KFP07542.1 - 0.0001 21.8 0.0 0.00026 20.5 0.0 1.6 1 0 0 1 1 1 1 Homeobox domain PRP21_like_P PF12230.3 KFP07542.1 - 0.0005 19.6 0.3 0.51 9.8 0.1 2.6 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein DUF2719 PF10891.3 KFP07542.1 - 0.18 11.4 6.4 0.37 10.4 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2719) DUF668 PF05003.7 KFP07542.1 - 0.19 11.9 0.0 0.56 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF668) zf-C2H2_4 PF13894.1 KFP07542.1 - 4.9 7.7 47.0 0.53 10.7 0.2 8.0 8 0 0 8 8 8 0 C2H2-type zinc finger Kazal_2 PF07648.10 KFP07543.1 - 1.1e-14 54.0 36.3 5.8e-07 29.3 0.4 5.7 4 1 0 5 5 5 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP07543.1 - 9.3e-12 44.7 32.2 7.1e-05 22.7 2.6 5.7 3 1 1 4 4 4 3 Kazal-type serine protease inhibitor domain VWC PF00093.13 KFP07543.1 - 0.0054 16.8 4.1 0.0054 16.8 2.8 9.6 7 3 4 11 11 11 2 von Willebrand factor type C domain Ldl_recept_a PF00057.13 KFP07543.1 - 0.0069 16.2 4.1 0.0069 16.2 2.9 6.7 5 1 1 6 6 6 2 Low-density lipoprotein receptor domain class A Pkinase PF00069.20 KFP07544.1 - 2.5e-49 167.7 0.0 4.1e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07544.1 - 1.7e-32 112.4 0.0 2.4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.7 KFP07544.1 - 2.5e-17 61.8 0.6 4.9e-17 60.9 0.4 1.5 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Activin_recp PF01064.18 KFP07544.1 - 2.7e-12 47.1 6.7 6.8e-12 45.8 4.7 1.7 1 0 0 1 1 1 1 Activin types I and II receptor domain APH PF01636.18 KFP07544.1 - 0.0088 15.8 0.0 0.022 14.4 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family AAA PF00004.24 KFP07545.1 - 3.3e-32 111.4 0.0 5.2e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP07545.1 - 3e-08 33.8 0.0 7.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFP07545.1 - 9.7e-08 32.8 0.1 4.9e-07 30.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFP07545.1 - 2e-07 31.3 0.8 3.5e-06 27.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KFP07545.1 - 1.3e-06 28.5 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFP07545.1 - 2.9e-05 23.9 0.1 7.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFP07545.1 - 3.5e-05 23.7 0.1 6.4e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KFP07545.1 - 4.3e-05 22.6 0.2 0.03 13.3 0.0 2.2 1 1 1 2 2 2 2 KAP family P-loop domain Arch_ATPase PF01637.13 KFP07545.1 - 4.8e-05 23.1 1.1 0.009 15.7 0.8 2.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KFP07545.1 - 6.9e-05 22.3 0.4 0.022 14.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KFP07545.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 KFP07545.1 - 0.00021 20.9 0.0 0.00058 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFP07545.1 - 0.00042 20.0 0.1 0.0012 18.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 KFP07545.1 - 0.00054 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 KFP07545.1 - 0.0008 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 KFP07545.1 - 0.001 18.2 0.0 0.0042 16.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFP07545.1 - 0.002 18.1 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFP07545.1 - 0.002 17.7 0.2 0.0072 16.0 0.1 2.0 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 KFP07545.1 - 0.0021 18.2 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.13 KFP07545.1 - 0.0034 16.9 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 KFP07545.1 - 0.0037 16.2 0.1 0.014 14.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFP07545.1 - 0.004 17.4 0.1 0.01 16.1 0.0 1.8 2 0 0 2 2 1 1 ABC transporter PduV-EutP PF10662.4 KFP07545.1 - 0.0051 16.3 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 KFP07545.1 - 0.007 15.9 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFP07545.1 - 0.0075 15.8 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFP07545.1 - 0.008 14.9 0.1 0.014 14.1 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus Zeta_toxin PF06414.7 KFP07545.1 - 0.0084 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KaiC PF06745.8 KFP07545.1 - 0.01 14.9 0.1 0.54 9.3 0.0 2.4 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 KFP07545.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KFP07545.1 - 0.017 14.3 0.0 0.08 12.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 KFP07545.1 - 0.026 13.6 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KFP07545.1 - 0.036 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MobB PF03205.9 KFP07545.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KFP07545.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 KFP07545.1 - 0.048 13.1 0.1 0.22 10.9 0.1 1.9 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_3 PF07726.6 KFP07545.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KFP07545.1 - 0.27 11.1 1.2 2.6 8.0 0.2 2.8 2 1 0 2 2 1 0 50S ribosome-binding GTPase DUF3512 PF12024.3 KFP07546.1 - 1.5e-88 296.2 1.7 1.5e-88 296.2 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) Bromodomain PF00439.20 KFP07546.1 - 1.7e-22 79.1 0.1 1.3e-21 76.3 0.1 2.3 2 0 0 2 2 2 1 Bromodomain Tox-ART-HYE1 PF15634.1 KFP07546.1 - 0.08 11.9 0.0 0.08 11.9 0.0 2.2 2 0 0 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase SR-25 PF10500.4 KFP07546.1 - 0.34 10.3 21.3 0.014 14.8 9.4 2.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF1510 PF07423.6 KFP07546.1 - 0.42 9.9 13.2 0.94 8.8 9.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KFP07546.1 - 1.2 7.1 12.8 2.3 6.1 8.9 1.4 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.6 KFP07546.1 - 9.8 5.7 26.2 4.9 6.7 15.3 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Borrelia_P83 PF05262.6 KFP07547.1 - 0.036 12.3 1.3 0.036 12.3 0.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein p25-alpha PF05517.7 KFP07548.1 - 1.5e-57 194.2 4.5 1.6e-57 194.0 3.1 1.0 1 0 0 1 1 1 1 p25-alpha Rep_3 PF01051.16 KFP07548.1 - 0.022 14.3 0.3 0.028 14.0 0.2 1.1 1 0 0 1 1 1 0 Initiator Replication protein CesA PF11439.3 KFP07548.1 - 0.035 14.0 0.2 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Drf_FH3 PF06367.11 KFP07548.1 - 0.044 13.1 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain Na_H_Exchanger PF00999.16 KFP07549.1 - 1.2e-79 267.6 45.1 1.4e-79 267.4 31.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LRR_4 PF12799.2 KFP07550.1 - 3.4e-05 23.3 5.6 0.068 12.8 0.1 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFP07550.1 - 0.00093 19.0 3.8 25 5.3 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.1 KFP07550.1 - 0.0053 16.4 1.1 0.0053 16.4 0.7 3.8 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 KFP07550.1 - 0.13 12.3 12.6 7.7 6.9 0.1 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KFP07550.1 - 0.32 11.3 8.2 45 4.9 0.0 6.2 5 1 1 6 6 6 0 Leucine rich repeat AA_permease PF00324.16 KFP07551.1 - 1e-49 169.2 21.1 8.1e-38 129.9 5.4 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KFP07551.1 - 9.2e-20 70.5 25.1 2.6e-18 65.8 17.4 2.1 1 1 0 1 1 1 1 Amino acid permease zf-NF-X1 PF01422.12 KFP07552.1 - 4.6e-19 67.9 189.7 8.2e-06 25.6 6.0 13.8 10 4 2 12 12 12 8 NF-X1 type zinc finger R3H PF01424.17 KFP07552.1 - 1.7e-16 59.6 0.1 3.6e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 R3H domain Laminin_II PF06009.7 KFP07553.1 - 0.069 12.9 0.1 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Laminin Domain II PTB PF08416.8 KFP07556.1 - 3.8e-42 143.2 0.0 6.9e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotyrosine-binding domain SH2 PF00017.19 KFP07556.1 - 1.1e-09 37.9 0.0 3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain PTEN_C2 PF10409.4 KFP07556.1 - 8.3e-08 32.0 0.0 2.7e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.22 KFP07556.1 - 0.01 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFP07556.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Thyroglobulin_1 PF00086.13 KFP07557.1 - 9.2e-21 72.9 3.7 1.9e-20 71.9 2.5 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF4657 PF15552.1 KFP07557.1 - 0.13 11.5 0.5 0.17 11.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) zf-CCHC_5 PF14787.1 KFP07557.1 - 0.57 9.7 7.7 5.6 6.5 0.0 2.8 2 1 0 2 2 2 0 GAG-polyprotein viral zinc-finger Glycos_transf_2 PF00535.21 KFP07558.1 - 5.4e-08 32.7 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP07560.1 - 1.2e-22 80.1 0.3 1.7e-22 79.7 0.2 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.21 KFP07560.1 - 2.5e-16 59.8 0.0 5.4e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 KFP07560.1 - 2.5e-08 33.2 0.2 6.2e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP07560.1 - 0.00044 19.4 0.0 0.0051 15.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KFP07560.1 - 0.037 13.8 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 RicinB_lectin_2 PF14200.1 KFP07560.1 - 0.13 12.6 0.0 6 7.2 0.0 2.4 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Glycos_transf_2 PF00535.21 KFP07561.1 - 6.8e-22 77.9 0.0 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP07561.1 - 7.6e-21 74.4 0.8 1.6e-20 73.3 0.5 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFP07561.1 - 7.4e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFP07561.1 - 7.7e-07 28.4 0.0 1.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP07561.1 - 3e-06 26.5 0.0 3.7e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 HMG_box_2 PF09011.5 KFP07562.1 - 8.2e-44 147.8 14.9 3e-27 94.7 4.7 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KFP07562.1 - 7.9e-41 138.1 12.9 8.9e-26 89.9 1.1 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_5 PF14887.1 KFP07562.1 - 0.00011 21.8 11.0 0.032 13.9 1.8 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box 5 Nucleoplasmin PF03066.10 KFP07562.1 - 0.24 10.9 10.4 0.4 10.2 7.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin SAP30_Sin3_bdg PF13867.1 KFP07563.1 - 2.7e-24 84.7 0.0 3.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-SAP30 PF13866.1 KFP07563.1 - 3.2e-10 39.5 0.3 5.8e-10 38.6 0.1 1.5 2 0 0 2 2 2 1 SAP30 zinc-finger SCRG1 PF15224.1 KFP07565.1 - 1.1e-44 150.1 4.0 1.2e-44 149.9 2.8 1.0 1 0 0 1 1 1 1 Scrapie-responsive protein 1 HLH PF00010.21 KFP07566.1 - 4.9e-19 67.7 0.6 4.9e-19 67.7 0.4 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain BetR PF08667.5 KFP07566.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 BetR domain Sec7 PF01369.15 KFP07567.1 - 1.1e-38 132.8 0.1 1.6e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.2 KFP07567.1 - 1.1e-07 31.5 0.6 2.7e-07 30.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFP07567.1 - 0.0041 16.7 1.3 0.0076 15.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 KFP07567.1 - 0.023 14.6 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 PRANC domain CEP44 PF15007.1 KFP07568.1 - 4.4e-53 178.5 2.4 5.1e-53 178.3 0.5 1.9 2 0 0 2 2 2 1 Centrosomal spindle body, CEP44 adh_short PF00106.20 KFP07569.1 - 8.2e-25 87.6 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFP07569.1 - 3.6e-12 46.5 0.0 5.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFP07569.1 - 1.2e-08 34.7 0.0 1.7e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFP07569.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Neur_chan_LBD PF02931.18 KFP07570.1 - 5e-54 182.7 0.1 7.3e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP07570.1 - 5.5e-44 150.8 6.0 6.6e-38 130.9 1.8 2.2 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF4227 PF14004.1 KFP07570.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) Myelin_PLP PF01275.14 KFP07572.1 - 1.6e-107 358.3 24.0 1.8e-107 358.2 16.6 1.0 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) DUF2701 PF10857.3 KFP07572.1 - 0.3 10.8 0.0 0.3 10.8 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2701) WD40 PF00400.27 KFP07573.1 - 3.7e-62 204.1 30.5 1.3e-10 40.7 0.1 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat Nup160 PF11715.3 KFP07573.1 - 7e-05 21.1 3.9 0.15 10.1 0.0 4.2 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Ank PF00023.25 KFP07574.1 - 9e-45 148.3 6.2 1.3e-09 37.4 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFP07574.1 - 2.1e-42 143.3 3.9 1.1e-18 67.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP07574.1 - 2e-32 110.9 0.9 4.7e-10 39.7 0.0 4.8 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07574.1 - 3e-31 104.3 4.9 5.4e-07 29.2 0.0 7.3 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KFP07574.1 - 1.1e-24 85.9 5.6 1.4e-07 31.5 0.0 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SOCS_box PF07525.11 KFP07574.1 - 7e-13 48.2 7.6 1.4e-12 47.2 5.2 1.6 1 0 0 1 1 1 1 SOCS box SPC22 PF04573.7 KFP07575.1 - 1.4e-53 180.7 0.1 1.7e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit AsmA_2 PF13502.1 KFP07575.1 - 0.081 12.2 0.3 0.13 11.6 0.2 1.4 1 1 0 1 1 1 0 AsmA-like C-terminal region Pyr_redox_2 PF07992.9 KFP07576.1 - 2.5e-16 60.1 0.0 4.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFP07576.1 - 0.0056 16.7 0.0 0.096 12.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S9 PF00380.14 KFP07577.1 - 7.8e-36 122.9 0.2 8.8e-36 122.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KFP07577.1 - 0.013 13.0 0.0 0.014 12.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Ank PF00023.25 KFP07578.1 - 5.1e-31 104.9 2.3 8.2e-08 31.6 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 KFP07578.1 - 1.2e-30 105.6 0.6 5.9e-14 52.1 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP07578.1 - 1.1e-28 99.0 3.2 6.5e-12 45.6 0.1 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP07578.1 - 3.8e-26 90.5 4.8 9.4e-12 44.7 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07578.1 - 2e-21 73.8 2.3 0.00014 21.7 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat C2 PF00168.25 KFP07579.1 - 8.4e-55 182.5 0.8 1.2e-26 92.4 0.3 2.2 2 0 0 2 2 2 2 C2 domain DUF1510 PF07423.6 KFP07579.1 - 0.00035 20.0 0.3 0.00097 18.5 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DOCK-C2 PF14429.1 KFP07579.1 - 0.012 15.2 0.4 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 KFP07579.1 - 0.02 14.4 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain Shisa PF13908.1 KFP07579.1 - 0.069 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 KFP07579.1 - 0.11 12.1 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 IncA protein Orthopox_F7 PF05813.7 KFP07579.1 - 0.72 9.7 5.1 1.8 8.5 2.8 2.2 2 0 0 2 2 2 0 Orthopoxvirus F7 protein E2F_TDP PF02319.15 KFP07581.1 - 2.5e-45 151.8 1.2 1.6e-21 75.5 0.2 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.7 KFP07581.1 - 9.9e-05 22.1 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC TrmB PF01978.14 KFP07581.1 - 0.00013 21.5 0.1 0.0013 18.4 0.1 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Cdc6_C PF09079.6 KFP07581.1 - 0.048 13.3 0.1 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 CDC6, C terminal Tim54 PF11711.3 KFP07581.1 - 0.43 9.1 4.0 0.26 9.8 0.9 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ank_2 PF12796.2 KFP07582.1 - 4.1e-44 148.8 2.2 4e-14 52.7 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07582.1 - 2.6e-39 131.1 2.4 6.8e-10 38.2 0.3 6.5 7 0 0 7 7 7 5 Ankyrin repeat zf-DHHC PF01529.15 KFP07582.1 - 4.1e-38 130.5 15.1 4.1e-38 130.5 10.5 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 KFP07582.1 - 1e-32 111.9 0.6 3.9e-10 39.9 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07582.1 - 1.4e-32 108.4 1.4 1.1e-05 25.1 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KFP07582.1 - 1.6e-29 101.2 3.9 6.2e-08 32.6 0.2 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Oxysterol_BP PF01237.13 KFP07583.1 - 6.4e-91 304.4 0.3 1.1e-90 303.7 0.2 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 KFP07583.1 - 7.2e-10 39.0 0.5 2.9e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 PH domain Cpn60_TCP1 PF00118.19 KFP07584.1 - 9.4e-05 21.2 0.0 0.23 10.0 0.0 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family NAP PF00956.13 KFP07585.1 - 4e-95 317.5 7.3 4e-95 317.5 5.1 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF2229 PF09989.4 KFP07585.1 - 0.013 14.9 0.7 0.02 14.3 0.5 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) ING PF12998.2 KFP07585.1 - 0.18 12.0 3.7 0.67 10.2 2.6 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF4484 PF14831.1 KFP07585.1 - 4.4 7.3 9.1 5.9 6.9 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Nop14 PF04147.7 KFP07585.1 - 6.6 4.5 18.4 0.89 7.3 6.5 2.2 2 0 0 2 2 2 0 Nop14-like family KH_1 PF00013.24 KFP07586.1 - 2.1e-05 24.0 0.1 0.00061 19.3 0.0 2.4 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KFP07586.1 - 0.00039 19.9 0.0 0.00082 18.9 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 KFP07586.1 - 0.0084 15.7 0.0 0.028 14.0 0.0 1.9 1 0 0 1 1 1 1 KH domain CAP PF00188.21 KFP07587.1 - 3.2e-20 72.8 3.6 4.1e-20 72.5 2.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Keratin PF02422.11 KFP07589.1 - 4.4e-30 103.5 9.5 4.7e-30 103.4 6.6 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07590.1 - 2.2e-23 82.0 25.6 1.1e-21 76.5 17.7 2.2 1 1 0 1 1 1 1 Keratin Collagen PF01391.13 KFP07590.1 - 0.47 10.0 22.6 0.16 11.5 13.9 1.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF3432 PF11914.3 KFP07590.1 - 1.2 9.1 7.8 1.9 8.5 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP07591.1 - 2.2e-23 82.0 25.6 1.1e-21 76.5 17.7 2.2 1 1 0 1 1 1 1 Keratin Collagen PF01391.13 KFP07591.1 - 0.47 10.0 22.6 0.16 11.5 13.9 1.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF3432 PF11914.3 KFP07591.1 - 1.2 9.1 7.8 1.9 8.5 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Keratin PF02422.11 KFP07592.1 - 1.9e-36 123.9 13.2 2e-36 123.8 9.1 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.12 KFP07592.1 - 0.1 12.6 6.8 0.14 12.3 4.7 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFP07593.1 - 1.5e-39 133.8 14.2 1.7e-39 133.7 9.8 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.12 KFP07593.1 - 0.34 11.0 6.6 0.44 10.7 4.6 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFP07595.1 - 2.5e-39 133.1 12.0 2.7e-39 133.0 8.3 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.12 KFP07595.1 - 0.36 10.9 6.8 0.48 10.5 4.7 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFP07596.1 - 2.6e-38 129.9 13.5 2.9e-38 129.7 9.4 1.0 1 0 0 1 1 1 1 Keratin UPF0515 PF15135.1 KFP07596.1 - 0.2 10.6 2.1 0.22 10.5 1.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 TIL PF01826.12 KFP07596.1 - 0.27 11.4 7.5 0.35 11.0 5.2 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFP07598.1 - 2.1e-42 143.0 10.2 2.3e-42 142.8 7.1 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07600.1 - 4.1e-43 145.3 9.9 4.5e-43 145.1 6.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07601.1 - 2.6e-38 129.9 10.7 2.8e-38 129.8 7.4 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07602.1 - 4.1e-43 145.3 9.9 4.5e-43 145.1 6.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07604.1 - 4.1e-43 145.3 9.9 4.5e-43 145.1 6.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07606.1 - 4.1e-43 145.3 9.9 4.5e-43 145.1 6.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07608.1 - 4.1e-43 145.3 9.9 4.5e-43 145.1 6.9 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07609.1 - 7.9e-15 54.6 3.2 8.5e-15 54.5 2.2 1.0 1 0 0 1 1 1 1 Keratin Keratin PF02422.11 KFP07610.1 - 7.6e-22 77.1 9.5 9.3e-22 76.8 6.6 1.0 1 0 0 1 1 1 1 Keratin TMEM171 PF15471.1 KFP07610.1 - 0.012 14.3 2.3 0.012 14.4 1.6 1.0 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF3432 PF11914.3 KFP07610.1 - 0.024 14.6 4.4 0.029 14.3 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) TIL PF01826.12 KFP07610.1 - 0.13 12.4 3.8 0.16 12.0 2.6 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFP07611.1 - 1.8e-31 107.9 13.6 2e-31 107.8 9.4 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.12 KFP07611.1 - 0.17 11.9 4.4 0.22 11.6 3.1 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFP07612.1 - 5.8e-36 122.3 13.7 6.4e-36 122.2 9.5 1.0 1 0 0 1 1 1 1 Keratin TIL PF01826.12 KFP07612.1 - 0.057 13.5 5.0 0.074 13.1 3.5 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Keratin PF02422.11 KFP07613.1 - 1.6e-23 82.5 8.8 1.7e-23 82.4 6.1 1.0 1 0 0 1 1 1 1 Keratin DUF3432 PF11914.3 KFP07613.1 - 0.035 14.1 2.2 0.041 13.9 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) S_100 PF01023.14 KFP07614.1 - 3.1e-19 68.0 1.0 4.5e-19 67.4 0.7 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.27 KFP07614.1 - 0.00053 19.1 0.9 0.0021 17.2 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFP07614.1 - 0.0008 19.4 0.3 0.0017 18.4 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair DEK_C PF08766.6 KFP07614.1 - 0.019 14.7 3.1 0.023 14.4 1.4 1.7 2 1 0 2 2 2 0 DEK C terminal domain S_100 PF01023.14 KFP07615.1 - 3.9e-20 70.8 0.5 6.7e-20 70.1 0.4 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 KFP07615.1 - 1.2e-06 28.5 0.2 1.5e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP07615.1 - 0.00014 20.9 0.4 0.0069 15.6 0.0 2.3 2 0 0 2 2 2 1 EF hand MSC PF09402.5 KFP07615.1 - 0.047 12.3 0.1 0.048 12.3 0.1 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain EF-hand_9 PF14658.1 KFP07615.1 - 0.099 12.5 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain DUF4460 PF14687.1 KFP07615.1 - 0.14 11.9 1.4 0.35 10.6 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) S_100 PF01023.14 KFP07616.1 - 6.2e-20 70.2 2.7 3.9e-19 67.6 0.3 2.2 1 1 1 2 2 2 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 KFP07616.1 - 0.00057 19.9 0.6 0.001 19.1 0.4 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP07616.1 - 0.002 17.3 0.5 0.002 17.3 0.4 2.8 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 KFP07616.1 - 0.051 13.3 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.1 KFP07616.1 - 0.058 13.2 5.2 0.99 9.4 1.3 3.0 1 1 0 2 2 2 0 EF-hand domain Rota_VP2 PF05087.7 KFP07616.1 - 0.096 10.5 0.0 0.1 10.5 0.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein EF-hand_7 PF13499.1 KFP07617.1 - 8.9e-08 32.1 0.3 1.5e-07 31.4 0.1 1.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP07617.1 - 7.4e-07 28.2 1.0 0.00015 20.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 KFP07617.1 - 1.9e-06 26.7 0.3 0.00082 18.5 0.1 2.5 2 0 0 2 2 2 2 EF hand S_100 PF01023.14 KFP07617.1 - 2e-06 26.9 0.0 3.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_6 PF13405.1 KFP07617.1 - 0.0022 17.7 0.0 0.55 10.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFP07617.1 - 0.0039 16.7 1.4 0.029 13.9 0.6 2.3 2 1 0 2 2 2 1 EF-hand domain pair S_100 PF01023.14 KFP07618.1 - 2e-06 27.0 0.0 3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain S_100 PF01023.14 KFP07619.1 - 1.1e-11 43.8 0.2 1.8e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 KFP07619.1 - 0.0034 17.4 0.3 0.012 15.7 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain pair TPR_15 PF13429.1 KFP07619.1 - 0.013 14.5 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-hand_1 PF00036.27 KFP07619.1 - 0.014 14.6 0.2 6.7 6.2 0.1 2.7 3 0 0 3 3 3 0 EF hand DUF3702 PF12486.3 KFP07619.1 - 0.12 12.0 0.1 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 ImpA domain protein S_100 PF01023.14 KFP07620.1 - 1.4e-21 75.4 1.8 1.6e-21 75.3 1.2 1.0 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain PRESAN PF09687.5 KFP07620.1 - 0.048 13.7 0.1 0.053 13.5 0.1 1.0 1 0 0 1 1 1 0 Plasmodium RESA N-terminal FoP_duplication PF13865.1 KFP07621.1 - 3.5e-20 72.2 6.5 3.5e-20 72.2 4.5 3.8 2 1 3 5 5 5 1 C-terminal duplication domain of Friend of PRMT1 Sbi-IV PF11621.3 KFP07621.1 - 1.5 8.9 10.3 7.8 6.7 0.0 3.8 2 2 2 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI Snapin_Pallidin PF14712.1 KFP07622.1 - 5.1e-17 61.9 3.4 6.2e-17 61.6 2.3 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Laminin_II PF06009.7 KFP07622.1 - 0.17 11.6 1.6 0.19 11.5 1.1 1.1 1 0 0 1 1 1 0 Laminin Domain II Vac_Fusion PF02346.11 KFP07622.1 - 0.64 9.4 3.2 0.34 10.3 0.5 1.7 2 0 0 2 2 2 0 Chordopoxvirus fusion protein SERTA PF06031.8 KFP07622.1 - 4.2 6.7 6.5 1.8 7.9 2.2 2.1 2 1 0 2 2 2 0 SERTA motif Guanylate_cyc PF00211.15 KFP07623.1 - 2.4e-39 134.6 0.0 1.8e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 KFP07623.1 - 1.4e-05 24.4 0.9 2e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 Heme NO binding associated Pkinase_Tyr PF07714.12 KFP07623.1 - 0.00029 19.9 0.0 0.00051 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.2 KFP07623.1 - 0.44 10.3 2.7 4.5 7.0 0.2 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RVT_1 PF00078.22 KFP07624.1 - 5.2e-16 58.6 0.0 7e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.22 KFP07625.1 - 1.8e-43 147.7 0.0 3.3e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 KFP07625.1 - 2.3e-07 30.4 3.3 4.5e-07 29.4 2.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TonB_2 PF13103.1 KFP07625.1 - 0.003 17.5 0.1 0.0091 16.0 0.1 1.8 1 0 0 1 1 1 1 TonB C terminal DUF2968 PF11180.3 KFP07625.1 - 0.057 12.8 5.7 0.096 12.0 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Tropomyosin_1 PF12718.2 KFP07625.1 - 0.067 13.0 7.1 0.15 11.9 4.9 1.5 1 0 0 1 1 1 0 Tropomyosin like ERM PF00769.14 KFP07625.1 - 1.3 8.5 10.4 1.6 8.2 6.0 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 KFP07625.1 - 1.4 8.4 11.7 6.7 6.2 6.7 2.2 2 0 0 2 2 2 0 IncA protein Prok-RING_1 PF14446.1 KFP07625.1 - 1.6 8.5 6.4 4.2 7.1 4.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ASC PF00858.19 KFP07626.1 - 3.1e-186 619.2 0.4 3.7e-186 619.0 0.3 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel SWIB PF02201.13 KFP07627.1 - 2.2e-26 91.3 0.1 6.8e-26 89.7 0.1 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain SusD PF07980.6 KFP07627.1 - 0.11 11.9 1.0 0.16 11.4 0.1 1.7 2 0 0 2 2 2 0 SusD family NAD_Gly3P_dh_C PF07479.9 KFP07628.1 - 7.7e-57 191.1 0.1 1.2e-56 190.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KFP07628.1 - 7.6e-49 165.4 0.0 2e-48 164.0 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KFP07628.1 - 0.11 12.9 0.1 1.6 9.1 0.0 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF643 PF04867.7 KFP07628.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF643) TRAM_LAG1_CLN8 PF03798.11 KFP07629.1 - 3e-38 131.3 28.5 3.6e-38 131.1 19.8 1.1 1 0 0 1 1 1 1 TLC domain Homeobox PF00046.24 KFP07629.1 - 1.1e-07 31.3 0.2 1.9e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 KFP07630.1 - 5.9e-07 29.4 3.9 1.1e-06 28.5 2.7 1.5 1 0 0 1 1 1 1 LIM domain SUZ PF12752.2 KFP07630.1 - 1.1 9.8 6.6 2.2 8.8 1.2 3.0 2 0 0 2 2 2 0 SUZ domain HCO3_cotransp PF00955.16 KFP07631.1 - 4e-122 408.4 3.0 4.7e-122 408.2 2.1 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFP07631.1 - 7e-98 327.2 0.0 1.1e-97 326.5 0.0 1.3 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Tetraspannin PF00335.15 KFP07632.1 - 7e-34 117.0 8.4 8.6e-34 116.7 5.8 1.1 1 0 0 1 1 1 1 Tetraspanin family 7tm_1 PF00001.16 KFP07633.1 - 4e-61 206.4 22.7 5.4e-61 205.9 15.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP07633.1 - 3.7e-06 26.3 21.1 5e-06 25.8 14.6 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Cnd2 PF05786.9 KFP07634.1 - 3.1e-16 59.1 0.2 3.1e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF3450 PF11932.3 KFP07636.1 - 0.0027 17.0 12.1 0.0027 17.0 8.4 5.9 2 2 4 6 6 6 1 Protein of unknown function (DUF3450) EcoRI PF02963.11 KFP07637.1 - 0.039 12.7 0.3 0.1 11.3 0.1 1.8 2 0 0 2 2 2 0 Restriction endonuclease EcoRI MBD_C PF14048.1 KFP07638.1 - 4.8e-26 91.1 0.0 5.9e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 Pardaxin PF07425.6 KFP07638.1 - 0.024 14.0 0.6 0.065 12.6 0.4 1.7 1 0 0 1 1 1 0 Pardaxin zf-H2C2_2 PF13465.1 KFP07639.1 - 1e-22 79.2 31.9 1.1e-08 34.9 2.1 6.6 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFP07639.1 - 5.3e-16 57.9 47.3 0.00011 22.2 0.9 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07639.1 - 8.9e-09 35.0 43.6 0.0012 19.0 0.6 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP07639.1 - 0.00026 21.0 25.8 0.16 12.1 0.3 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP07639.1 - 0.054 13.4 39.3 0.25 11.3 3.2 7.4 7 1 0 7 7 7 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP07639.1 - 0.059 13.6 1.0 0.059 13.6 0.7 6.0 6 0 0 6 6 6 0 C2H2-type zinc-finger domain GAGA PF09237.6 KFP07639.1 - 0.099 12.2 0.1 0.099 12.2 0.0 2.8 2 1 1 3 3 3 0 GAGA factor zf-met PF12874.2 KFP07639.1 - 0.1 12.8 0.2 0.1 12.8 0.1 5.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type GATA PF00320.22 KFP07639.1 - 0.14 11.5 3.1 8.4 5.8 0.1 3.7 3 0 0 3 3 3 0 GATA zinc finger RNHCP PF12647.2 KFP07639.1 - 0.3 10.9 0.1 0.3 10.9 0.1 4.7 4 1 2 6 6 6 0 RNHCP domain Peptidase_M24 PF00557.19 KFP07640.1 - 7.1e-27 94.3 0.1 8.4e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 adh_short PF00106.20 KFP07641.1 - 6.3e-32 110.8 0.9 7.7e-32 110.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFP07641.1 - 3.3e-12 46.4 0.4 4.5e-12 45.9 0.3 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFP07641.1 - 6.7e-09 35.8 0.1 8.3e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.9 KFP07641.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.1 KFP07641.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.18 KFP07641.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Rad52_Rad22 PF04098.10 KFP07642.1 - 1.2e-07 31.5 0.1 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.17 KFP07642.1 - 0.00025 20.6 0.0 0.00065 19.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07642.1 - 0.0028 17.4 0.1 0.0083 15.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1953 PF09196.5 KFP07642.1 - 0.0065 16.1 0.1 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1953) RRM_6 PF14259.1 KFP07642.1 - 0.051 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Hormone_1 PF00103.15 KFP07643.1 - 1.9e-15 56.8 0.0 2e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Somatotropin hormone family Ion_trans PF00520.26 KFP07644.1 - 7e-125 413.9 77.4 4.9e-53 179.3 14.8 3.5 4 0 0 4 4 4 3 Ion transport protein Na_trans_assoc PF06512.8 KFP07644.1 - 3.5e-58 197.4 4.1 2.3e-39 135.8 2.7 2.5 2 0 0 2 2 2 2 Sodium ion transport-associated PKD_channel PF08016.7 KFP07644.1 - 1.9e-09 36.4 57.5 7.1e-06 24.6 0.1 6.6 4 3 2 6 6 6 5 Polycystin cation channel IQ PF00612.22 KFP07644.1 - 0.0003 20.1 1.2 0.00076 18.9 0.9 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Collagen PF01391.13 KFP07645.1 - 4.9e-59 195.7 273.2 7e-08 31.8 15.7 10.6 2 1 5 7 7 7 6 Collagen triple helix repeat (20 copies) C1q PF00386.16 KFP07645.1 - 3.8e-36 123.8 0.1 4.7e-36 123.5 0.1 1.1 1 0 0 1 1 1 1 C1q domain Glyco_transf_29 PF00777.13 KFP07646.1 - 9.6e-72 241.3 0.0 1.2e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Coprogen_oxidas PF01218.13 KFP07647.1 - 6e-124 412.3 0.0 6.7e-124 412.2 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SNF2_N PF00176.18 KFP07648.1 - 2.2e-81 272.9 0.3 2.2e-81 272.9 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFP07648.1 - 1.6e-11 43.8 0.0 4.1e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFP07648.1 - 0.00014 21.7 2.1 0.00028 20.7 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit 7tm_1 PF00001.16 KFP07649.1 - 1.7e-46 158.4 19.7 2.9e-46 157.7 13.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP07649.1 - 0.00032 19.8 18.3 0.00048 19.3 12.5 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx EXOSC1 PF10447.4 KFP07649.1 - 0.059 13.3 0.2 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 Serpentine_r_xa PF03383.10 KFP07649.1 - 1.9 8.2 12.4 0.19 11.4 1.6 2.3 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa TIP41 PF04176.8 KFP07650.1 - 5.4e-74 247.3 0.7 6.5e-74 247.1 0.5 1.1 1 0 0 1 1 1 1 TIP41-like family Got1 PF04178.7 KFP07651.1 - 1.6e-32 112.0 15.8 2.4e-32 111.5 10.7 1.4 1 1 1 2 2 2 2 Got1/Sft2-like family DUF2244 PF10003.4 KFP07651.1 - 1.4 8.2 15.2 0.1 11.9 3.5 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) PhaG_MnhG_YufB PF03334.9 KFP07651.1 - 3.6 7.7 10.1 1.4 8.9 4.5 2.1 1 1 1 2 2 2 0 Na+/H+ antiporter subunit T-box PF00907.17 KFP07652.1 - 9.7e-79 263.1 0.0 1.3e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 T-box IL8 PF00048.15 KFP07653.1 - 9e-11 41.5 0.4 1.1e-10 41.3 0.3 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like DERM PF14704.1 KFP07654.1 - 8e-28 97.3 3.5 9.7e-28 97.0 2.4 1.1 1 0 0 1 1 1 1 Dermatopontin NDK PF00334.14 KFP07655.1 - 7.9e-72 239.3 0.0 8.9e-40 135.6 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF2249 PF10006.4 KFP07655.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) DASH_Hsk3 PF08227.6 KFP07656.1 - 4.7e-15 55.4 0.1 1.5e-14 53.9 0.1 1.9 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Mig-14 PF07395.6 KFP07656.1 - 0.073 12.0 0.8 0.12 11.3 0.5 1.3 1 0 0 1 1 1 0 Mig-14 MbeD_MobD PF04899.7 KFP07656.1 - 0.1 12.5 0.5 0.1 12.5 0.3 3.3 1 1 2 3 3 3 0 MbeD/MobD like DivIVA PF05103.8 KFP07656.1 - 2.8 7.9 14.9 0.64 10.0 2.3 2.6 3 0 0 3 3 3 0 DivIVA protein Folate_carrier PF01770.13 KFP07658.1 - 6.4e-175 581.5 25.7 7.7e-175 581.3 17.8 1.1 1 0 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.11 KFP07658.1 - 2.7e-09 36.2 20.8 2.7e-09 36.2 14.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily F5_F8_type_C PF00754.20 KFP07659.1 - 4.3e-55 185.0 5.0 2.3e-28 98.6 0.5 3.2 2 0 0 2 2 2 2 F5/8 type C domain Cu-oxidase_3 PF07732.10 KFP07659.1 - 8e-31 106.2 0.6 2.4e-08 33.7 0.0 5.9 5 1 0 5 5 5 4 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFP07659.1 - 1.1e-13 50.8 3.6 0.00012 21.6 0.2 5.9 5 1 0 5 5 5 4 Multicopper oxidase Autophagy_N PF03986.8 KFP07660.1 - 1.4e-54 183.7 1.3 2e-54 183.3 0.6 1.4 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KFP07660.1 - 1.3e-25 89.2 6.0 1.4e-25 89.2 3.0 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KFP07660.1 - 8.5e-16 56.7 0.7 1.6e-15 55.9 0.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Nuc_sug_transp PF04142.10 KFP07661.1 - 3.2e-79 265.4 7.9 4.5e-79 264.9 5.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KFP07661.1 - 3.5e-07 29.4 12.9 5.8e-07 28.7 8.9 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFP07661.1 - 1.7e-06 28.0 6.3 1.7e-06 28.0 4.3 3.2 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KFP07661.1 - 0.0016 18.6 7.3 0.0016 18.6 5.0 2.9 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 KFP07661.1 - 0.42 10.2 21.6 0.02 14.5 4.9 3.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF4131 PF13567.1 KFP07661.1 - 8.9 5.6 17.4 5.4 6.3 3.3 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) DUF4174 PF13778.1 KFP07662.1 - 5.5e-90 297.4 0.2 2.2e-35 121.3 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4174) DUF2570 PF10828.3 KFP07662.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) V-set PF07686.12 KFP07663.1 - 8.2e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP07663.1 - 3.1e-06 27.0 0.4 9.4e-06 25.4 0.1 1.9 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain I-set PF07679.11 KFP07663.1 - 0.00014 21.6 0.0 0.028 14.2 0.0 2.4 2 1 0 2 2 2 2 Immunoglobulin I-set domain ig PF00047.20 KFP07663.1 - 0.0014 18.6 0.8 0.0046 17.0 0.2 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.1 KFP07663.1 - 0.0033 17.9 0.2 8.7 6.9 0.0 3.4 3 0 0 3 3 3 1 Immunoglobulin domain MMR_HSR1 PF01926.18 KFP07664.1 - 6e-20 71.3 0.0 7.5e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP07664.1 - 4.3e-09 36.0 0.0 1.2e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFP07664.1 - 2.5e-06 26.8 0.0 4.5e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KFP07664.1 - 2.3e-05 24.2 0.1 0.034 13.9 0.0 2.1 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.5 KFP07664.1 - 4.4e-05 22.7 0.0 5.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFP07664.1 - 5.9e-05 23.5 0.0 0.00029 21.2 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KFP07664.1 - 0.00015 21.0 0.0 0.00024 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 KFP07664.1 - 0.0046 15.8 0.0 0.007 15.2 0.0 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_21 PF13304.1 KFP07664.1 - 0.0073 16.3 0.0 0.0088 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KFP07664.1 - 0.0088 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KFP07664.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFP07664.1 - 0.033 14.0 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KFP07664.1 - 0.035 13.2 0.0 0.062 12.4 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFP07664.1 - 0.051 13.0 0.0 0.39 10.2 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PRTase_2 PF15609.1 KFP07664.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase AAA_16 PF13191.1 KFP07664.1 - 0.092 12.7 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 KFP07664.1 - 0.098 12.1 0.0 1 8.8 0.0 2.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein TFIID-18kDa PF02269.11 KFP07665.1 - 1.6e-38 130.3 0.4 1.8e-38 130.1 0.3 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit GTP_EFTU_D2 PF03144.20 KFP07665.1 - 0.078 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF4477 PF14780.1 KFP07666.1 - 1.7e-48 164.5 3.6 2.6e-48 163.8 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) I-set PF07679.11 KFP07668.1 - 8.6e-48 160.1 0.0 2.7e-17 62.4 0.0 5.1 6 0 0 6 6 6 4 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP07668.1 - 7.7e-40 134.8 0.0 2.2e-11 43.7 0.0 4.5 4 0 0 4 4 4 4 Immunoglobulin domain fn3 PF00041.16 KFP07668.1 - 1.9e-36 124.0 1.4 6.1e-13 48.7 0.0 3.5 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.20 KFP07668.1 - 2e-24 85.4 0.0 3.5e-07 30.2 0.0 5.4 6 0 0 6 6 6 3 Immunoglobulin domain Ig_3 PF13927.1 KFP07668.1 - 4.6e-20 71.8 0.1 2.5e-07 31.0 0.1 4.8 4 0 0 4 4 4 2 Immunoglobulin domain V-set PF07686.12 KFP07668.1 - 1e-13 51.1 1.5 0.00039 20.3 0.0 6.2 3 2 0 4 4 4 3 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP07668.1 - 3.7e-10 39.5 0.5 0.01 15.7 0.0 4.6 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.7 KFP07668.1 - 6.4e-05 22.8 0.0 0.36 10.7 0.0 4.1 3 1 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family C1-set PF07654.10 KFP07668.1 - 0.0073 16.2 0.0 1.9 8.5 0.0 4.3 3 1 0 3 3 3 1 Immunoglobulin C1-set domain C2-set PF05790.10 KFP07668.1 - 0.023 14.6 0.0 20 5.2 0.0 3.6 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Y_Y_Y PF07495.8 KFP07668.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Y_Y_Y domain CD34_antigen PF06365.7 KFP07668.1 - 0.33 10.5 0.8 0.49 10.0 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family Lzipper-MIP1 PF14389.1 KFP07670.1 - 0.0058 16.7 0.4 0.0058 16.7 0.3 3.9 3 1 1 4 4 4 1 Leucine-zipper of ternary complex factor MIP1 ACCA PF03255.9 KFP07670.1 - 3.8 7.0 18.2 0.64 9.5 2.0 3.5 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CENP-B_dimeris PF09026.5 KFP07670.1 - 7.3 6.8 12.1 80 3.5 7.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LSR PF05624.9 KFP07671.1 - 2.5e-19 68.7 33.7 3.8e-19 68.1 23.4 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) V-set PF07686.12 KFP07671.1 - 0.0028 17.5 0.1 0.017 14.9 0.0 2.3 1 1 0 1 1 1 1 Immunoglobulin V-set domain Apo-VLDL-II PF05418.6 KFP07672.1 - 3.2e-46 155.4 0.1 3.8e-46 155.1 0.1 1.1 1 0 0 1 1 1 1 Apovitellenin I (Apo-VLDL-II) XendoU PF09412.5 KFP07672.1 - 0.06 12.3 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Endoribonuclease XendoU ATG_C PF09333.6 KFP07673.1 - 5.3e-06 26.4 0.0 3.1e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain COX6C PF02937.10 KFP07674.1 - 1.2e-30 105.1 1.5 1.4e-30 105.0 1.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc Ribosomal_S24e PF01282.14 KFP07674.1 - 0.061 13.1 0.2 0.08 12.7 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S24e RGS PF00615.14 KFP07675.1 - 4.9e-09 36.3 0.1 6.2e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain HHH_3 PF12836.2 KFP07675.1 - 0.0013 18.5 0.0 0.0046 16.8 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif IBR PF01485.16 KFP07676.1 - 7.3e-07 28.9 5.6 7.3e-07 28.9 3.9 1.9 2 0 0 2 2 2 1 IBR domain DNA_RNApol_7kD PF03604.8 KFP07677.1 - 5.5e-18 64.1 8.9 8.3e-18 63.5 6.2 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 KFP07677.1 - 0.0012 18.2 1.0 0.0023 17.3 0.7 1.5 1 0 0 1 1 1 1 A2L zinc ribbon domain HypA PF01155.14 KFP07677.1 - 0.008 15.8 2.6 0.012 15.2 1.8 1.3 1 1 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KFP07677.1 - 0.0088 15.8 2.6 0.012 15.3 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon Cytochrome_C7 PF14522.1 KFP07677.1 - 0.0098 15.5 0.5 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c7 zf-CHY PF05495.7 KFP07677.1 - 0.045 13.8 3.5 0.067 13.3 2.4 1.3 1 1 0 1 1 1 0 CHY zinc finger zf-ISL3 PF14690.1 KFP07677.1 - 0.1 12.6 1.8 0.1 12.6 1.3 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Mu-like_Com PF10122.4 KFP07677.1 - 0.13 11.3 5.7 0.51 9.4 0.0 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com DUF2082 PF09855.4 KFP07677.1 - 0.18 11.6 0.7 0.18 11.6 0.5 1.7 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_5 PF13719.1 KFP07677.1 - 0.22 11.1 2.5 3.3 7.3 1.7 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFP07677.1 - 0.23 11.1 2.8 5 6.9 2.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 KFP07677.1 - 0.61 10.3 5.8 2 8.7 2.4 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2296 PF10058.4 KFP07677.1 - 0.97 9.2 3.6 5.7 6.7 2.5 2.0 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Ribosomal_L44 PF00935.14 KFP07677.1 - 1.1 9.3 5.5 11 6.0 2.2 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Ribosomal_L37e PF01907.14 KFP07677.1 - 3.3 7.5 5.6 4.9 7.0 3.9 1.4 1 1 0 1 1 1 0 Ribosomal protein L37e RRN7 PF11781.3 KFP07677.1 - 4.3 6.9 6.8 12 5.5 0.3 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 KFP07677.1 - 4.8 6.8 7.0 15 5.2 2.8 2.4 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger TPR_11 PF13414.1 KFP07678.1 - 4.1e-56 186.5 15.4 2.3e-16 59.1 0.4 6.3 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFP07678.1 - 2.1e-48 160.0 19.1 1.9e-06 27.2 0.2 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 KFP07678.1 - 7.3e-35 116.0 12.3 0.00028 20.5 0.1 9.6 8 1 1 9 9 9 9 Tetratricopeptide repeat RPAP3_C PF13877.1 KFP07678.1 - 7.9e-18 64.2 0.0 2.5e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_12 PF13424.1 KFP07678.1 - 2.8e-15 56.0 12.6 6.1e-06 26.0 0.2 6.9 3 3 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFP07678.1 - 4.2e-15 55.3 5.0 3.1e-06 26.9 0.0 5.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFP07678.1 - 2.9e-13 50.0 9.8 6.7e-05 23.4 0.0 6.8 4 3 3 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP07678.1 - 9.9e-13 46.8 22.9 0.00065 19.2 0.1 8.6 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFP07678.1 - 5.1e-11 41.5 8.2 0.098 12.5 0.0 7.1 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP07678.1 - 4.6e-10 39.6 9.4 0.031 14.5 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFP07678.1 - 1.7e-08 34.2 11.0 0.07 13.0 0.1 6.4 5 2 0 6 6 6 3 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 KFP07678.1 - 2.9e-07 30.5 6.8 0.079 13.6 0.0 7.8 6 2 4 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFP07678.1 - 5.6e-07 29.2 11.0 0.16 12.2 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP07678.1 - 5.9e-07 29.5 12.8 0.031 14.4 0.1 4.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFP07678.1 - 0.00048 20.4 8.9 12 6.6 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP07678.1 - 0.001 18.9 0.5 4.3 7.4 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFP07678.1 - 0.0014 18.7 0.3 0.031 14.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 KFP07678.1 - 0.015 15.1 14.2 2.4 8.1 0.1 5.7 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 KFP07678.1 - 0.017 14.3 3.3 38 3.6 0.0 5.7 7 0 0 7 7 7 0 SHNi-TPR IBR PF01485.16 KFP07679.1 - 1.3e-22 79.4 27.3 8.3e-16 57.6 8.2 5.1 4 1 1 5 5 5 2 IBR domain zf-RING_5 PF14634.1 KFP07679.1 - 0.0013 18.3 8.2 0.0013 18.3 5.7 4.3 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP07679.1 - 0.0024 17.6 9.4 0.0024 17.6 6.5 4.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 KFP07679.1 - 0.0024 17.4 9.3 0.0024 17.4 6.4 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.1 KFP07681.1 - 1.2e-22 79.8 1.1 2.4e-11 43.8 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFP07681.1 - 9.8e-19 67.4 0.1 1.8e-12 47.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07681.1 - 1.4e-18 65.6 1.8 1.5e-07 30.8 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KFP07681.1 - 1.4e-17 63.3 0.8 1.9e-12 46.9 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07681.1 - 4.8e-12 44.8 0.2 0.00056 19.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat DUF2795 PF11387.3 KFP07681.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) RRM_1 PF00076.17 KFP07682.1 - 1.2e-69 229.9 5.4 4.8e-25 86.9 0.2 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07682.1 - 1.2e-47 159.7 1.4 2e-16 59.6 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07682.1 - 7.5e-37 124.9 0.7 2.5e-10 40.0 0.0 4.6 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KFP07682.1 - 5e-35 118.9 0.4 2.1e-34 117.0 0.2 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 KFP07682.1 - 4.1e-07 29.6 1.9 0.12 12.1 0.1 3.6 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 KFP07682.1 - 6.7e-05 22.6 10.3 0.056 13.3 0.9 3.6 4 0 0 4 4 4 2 RNA binding motif CbiG_mid PF11761.3 KFP07682.1 - 0.0014 18.8 1.3 2 8.6 0.0 4.9 6 0 0 6 6 6 1 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 KFP07682.1 - 0.0016 18.1 0.0 2.3 8.0 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif ATP-grasp_2 PF08442.5 KFP07682.1 - 0.0016 17.8 0.3 1.8 7.8 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain DUF3421 PF11901.3 KFP07682.1 - 0.0067 16.1 0.1 5.6 6.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) OB_RNB PF08206.6 KFP07682.1 - 0.0072 15.8 2.9 3.3 7.2 0.0 3.5 3 0 0 3 3 3 1 Ribonuclease B OB domain DUF1464 PF07318.7 KFP07682.1 - 0.19 10.5 1.9 0.61 8.8 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1464) 14-3-3 PF00244.15 KFP07683.1 - 7.9e-109 362.2 9.5 8.9e-109 362.0 6.6 1.0 1 0 0 1 1 1 1 14-3-3 protein FliM PF02154.10 KFP07683.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM CIA30 PF08547.7 KFP07683.1 - 0.044 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) TPR_12 PF13424.1 KFP07683.1 - 0.045 13.6 0.2 0.48 10.3 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat CCDC-167 PF15188.1 KFP07683.1 - 0.92 9.4 4.2 0.6 10.0 0.3 2.5 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF3461 PF11944.3 KFP07683.1 - 2.6 7.9 5.7 9.6 6.0 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3461) 4F5 PF04419.9 KFP07684.1 - 1.5e-10 41.5 17.6 2.1e-10 41.1 12.2 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 KFP07684.1 - 2.6e-06 27.2 0.3 5e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding zf-met PF12874.2 KFP07684.1 - 4e-05 23.6 0.2 6.4e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP07684.1 - 0.0067 16.5 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFP07684.1 - 0.022 14.9 1.4 0.045 13.9 1.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-Di19 PF05605.7 KFP07684.1 - 0.041 14.0 0.7 0.067 13.3 0.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-FCS PF06467.9 KFP07684.1 - 0.051 13.2 0.2 0.097 12.3 0.2 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PRP21_like_P PF12230.3 KFP07684.1 - 0.14 11.6 4.3 0.17 11.3 3.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2 PF00096.21 KFP07684.1 - 0.15 12.4 1.6 0.22 11.9 1.1 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ribosomal_L44 PF00935.14 KFP07684.1 - 0.18 11.8 6.6 0.33 11.0 4.6 1.5 1 1 0 1 1 1 0 Ribosomal protein L44 AKAP95 PF04988.7 KFP07684.1 - 0.4 10.4 0.1 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Potyvirid-P3 PF13608.1 KFP07684.1 - 0.42 9.6 2.4 0.46 9.5 1.7 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF3449 PF11931.3 KFP07684.1 - 6.3 6.2 8.2 1.3 8.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) CP2 PF04516.10 KFP07685.1 - 3.5e-85 284.8 3.6 5.5e-85 284.1 2.5 1.3 1 0 0 1 1 1 1 CP2 transcription factor EF-hand_1 PF00036.27 KFP07686.1 - 2.6e-20 70.0 5.1 2.2e-07 29.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFP07686.1 - 4.3e-20 71.6 1.1 1.1e-10 41.4 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP07686.1 - 2.1e-18 64.7 2.6 1e-06 27.8 0.1 4.5 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KFP07686.1 - 2.7e-17 61.0 0.7 3.5e-06 26.4 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KFP07686.1 - 1.1e-11 44.1 5.9 3.7e-06 26.4 0.2 4.3 1 1 3 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP07686.1 - 3.1e-05 23.9 0.0 0.035 14.1 0.0 2.6 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFP07686.1 - 0.00064 19.4 0.3 0.12 12.1 0.0 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Ribonuc_red_sm PF00268.16 KFP07687.1 - 3.1e-123 410.2 0.4 3.6e-123 410.0 0.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HECT PF00632.20 KFP07688.1 - 2.3e-61 207.7 0.0 3.8e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) E3_UbLigase_EDD PF11547.3 KFP07688.1 - 1.1e-33 114.5 3.4 1.1e-33 114.5 2.4 2.2 2 0 0 2 2 2 1 E3 ubiquitin ligase EDD PABP PF00658.13 KFP07688.1 - 1.9e-22 78.6 0.0 4.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain zf-UBR PF02207.15 KFP07688.1 - 2.6e-07 30.2 21.9 5.8e-07 29.1 15.2 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) HSP20 PF00011.16 KFP07689.1 - 1.3e-11 44.1 0.1 1.5e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family C1-set PF07654.10 KFP07689.1 - 0.1 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin C1-set domain zf-H2C2_2 PF13465.1 KFP07690.1 - 4.9e-12 45.5 23.1 1.5e-07 31.3 1.4 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP07690.1 - 1.1e-11 44.2 25.2 0.00061 19.9 2.1 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07690.1 - 5e-09 35.8 19.6 0.0027 17.9 1.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger RRN7 PF11781.3 KFP07690.1 - 0.0078 15.6 2.9 0.59 9.6 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-TRAF PF02176.13 KFP07690.1 - 0.077 13.3 0.6 0.077 13.3 0.4 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 KFP07690.1 - 1.3 9.1 10.4 0.22 11.6 0.8 2.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KFP07690.1 - 8.3 6.2 10.0 0.32 10.7 1.0 2.4 2 0 0 2 2 2 0 BED zinc finger Orn_Arg_deC_N PF02784.11 KFP07691.1 - 1.5e-61 207.7 0.0 1.9e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFP07691.1 - 1.5e-21 76.2 0.0 2.4e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain V-ATPase_C PF03223.10 KFP07692.1 - 8.2e-149 495.5 11.4 2.9e-148 493.7 7.9 1.7 1 1 0 1 1 1 1 V-ATPase subunit C TraG_N PF07916.6 KFP07692.1 - 0.096 11.1 0.2 0.14 10.5 0.1 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2514 PF10721.4 KFP07693.1 - 2.4 7.8 5.0 2.6 7.7 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Frizzled PF01534.12 KFP07694.1 - 4e-130 433.3 17.5 5.3e-130 432.9 12.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFP07694.1 - 1e-27 96.7 6.2 2.6e-27 95.4 4.3 1.7 1 0 0 1 1 1 1 Fz domain Folate_rec PF03024.9 KFP07694.1 - 0.011 15.3 3.8 0.011 15.3 2.6 1.7 2 0 0 2 2 2 0 Folate receptor family DUF4014 PF13198.1 KFP07694.1 - 0.02 15.2 0.3 0.33 11.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) RseC_MucC PF04246.7 KFP07694.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Collagen PF01391.13 KFP07695.1 - 2.9e-07 29.9 6.7 4.9e-07 29.1 4.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mito_carr PF00153.22 KFP07696.1 - 5.1e-66 218.4 3.1 4.4e-25 87.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sof1 PF04158.9 KFP07697.1 - 5.7e-35 119.2 9.2 9.2e-35 118.5 6.4 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 KFP07697.1 - 3e-28 96.6 10.2 7.5e-06 25.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFP07697.1 - 2.4e-07 30.6 1.1 0.00021 21.0 0.0 3.6 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A DC_STAMP PF07782.8 KFP07698.1 - 5.7e-38 130.4 2.2 5.7e-38 130.4 1.5 1.8 2 0 0 2 2 2 1 DC-STAMP-like protein Golgin_A5 PF09787.4 KFP07698.1 - 0.018 13.6 0.1 0.035 12.6 0.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2975 PF11188.3 KFP07698.1 - 8.3 6.1 9.5 45 3.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Amidohydro_1 PF01979.15 KFP07699.1 - 8.5e-26 91.3 0.0 1e-25 91.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFP07699.1 - 2.2e-14 54.1 0.0 3.6e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFP07699.1 - 4.5e-12 45.6 0.2 1.5e-11 43.9 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFP07699.1 - 1e-07 31.5 0.5 0.00027 20.3 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 KFP07699.1 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.19 KFP07699.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel CUB PF00431.15 KFP07700.1 - 6.1e-48 161.4 0.8 1.4e-25 89.4 0.0 2.7 3 0 0 3 3 3 2 CUB domain Ldl_recept_a PF00057.13 KFP07700.1 - 5.2e-36 122.2 84.7 2.4e-11 43.3 10.1 5.6 5 0 0 5 5 5 5 Low-density lipoprotein receptor domain class A zf-C2H2_6 PF13912.1 KFP07701.1 - 1.9e-31 106.9 47.0 7.2e-08 32.0 0.9 7.6 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP07701.1 - 1.9e-10 40.5 42.6 0.049 13.7 0.3 8.2 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP07701.1 - 7.6e-08 32.2 53.0 0.0045 17.1 0.4 8.8 8 1 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFP07701.1 - 1.6e-06 28.0 64.4 0.011 16.0 0.2 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07701.1 - 0.0083 16.3 52.9 0.015 15.6 0.2 8.9 9 0 0 9 9 9 3 C2H2-type zinc finger TLD PF07534.11 KFP07703.1 - 6.7e-41 139.5 0.1 7.7e-41 139.3 0.1 1.0 1 0 0 1 1 1 1 TLD Costars PF14705.1 KFP07704.1 - 2.3e-33 113.9 0.0 4.3e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Costars Fibrinogen_C PF00147.13 KFP07705.1 - 6.7e-68 228.7 5.0 9.5e-68 228.3 3.5 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain KxDL PF10241.4 KFP07705.1 - 0.72 9.7 9.3 0.76 9.7 5.4 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF4239 PF14023.1 KFP07705.1 - 1.4 8.2 8.2 2.7 7.3 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) V_ATPase_I PF01496.14 KFP07705.1 - 1.5 6.6 11.6 2 6.1 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 KFP07705.1 - 3 6.9 15.5 5.2 6.1 10.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 KFP07705.1 - 5.8 5.2 13.6 8.3 4.7 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) VSP PF03302.8 KFP07707.1 - 0.0037 15.9 11.8 0.0037 15.9 8.2 1.7 1 1 1 2 2 2 1 Giardia variant-specific surface protein Toprim PF01751.17 KFP07707.1 - 0.029 14.3 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Toprim domain eIF3_N PF09440.5 KFP07708.1 - 5e-45 152.9 4.0 5e-45 152.9 2.8 2.1 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KFP07708.1 - 1.2e-18 67.3 0.1 5.4e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KFP07708.1 - 0.025 14.3 2.4 0.073 12.8 0.0 2.8 4 0 0 4 4 4 0 COP9 signalosome, subunit CSN8 HD_assoc PF13286.1 KFP07708.1 - 0.17 12.2 1.4 2.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Phosphohydrolase-associated domain TPR_14 PF13428.1 KFP07709.1 - 7.8e-12 44.7 6.5 0.0081 16.7 0.1 5.6 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFP07709.1 - 4.7e-11 43.0 2.7 0.0019 18.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP07709.1 - 5.6e-10 38.3 11.5 0.00046 19.8 0.5 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP07709.1 - 1.8e-09 37.8 7.5 2.4e-05 24.5 0.2 3.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFP07709.1 - 1.8e-09 37.0 12.6 0.00011 21.7 4.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFP07709.1 - 7e-07 28.5 4.7 0.046 13.3 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.3 KFP07709.1 - 0.00038 19.3 3.3 0.00038 19.3 2.3 2.5 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.1 KFP07709.1 - 0.0011 18.5 12.1 0.075 12.8 0.1 4.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP07709.1 - 0.0055 16.5 3.0 6.4 6.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFP07709.1 - 0.0055 16.8 6.0 0.018 15.1 3.0 3.5 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFP07709.1 - 0.0067 16.3 17.7 0.4 10.6 3.2 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 KFP07709.1 - 0.0091 16.0 1.4 0.16 12.1 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFP07709.1 - 0.015 15.0 1.8 3.6 7.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFP07709.1 - 0.022 15.1 7.9 7.2 7.3 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFP07709.1 - 0.074 12.9 4.0 9.6 6.1 0.1 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFP07709.1 - 0.16 12.2 9.1 1.6 8.9 0.4 2.8 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_17 PF13431.1 KFP07709.1 - 0.25 11.6 11.0 2.1 8.7 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Neurensin PF14927.1 KFP07710.1 - 2.4e-09 36.7 0.0 3.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Neurensin TLV_coat PF00429.14 KFP07711.1 - 0.048 12.1 0.2 0.054 11.9 0.1 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Gon7 PF08738.5 KFP07711.1 - 0.1 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Gon7 family 7tm_1 PF00001.16 KFP07712.1 - 5.9e-56 189.4 25.3 9.9e-56 188.7 17.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP07712.1 - 6.6e-10 38.5 24.8 1.5e-09 37.4 17.2 1.5 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP07712.1 - 0.014 14.5 30.1 0.13 11.3 20.9 2.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF2227 PF09988.4 KFP07712.1 - 0.03 13.9 0.0 0.1 12.1 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) Ribosomal_L18ae PF01775.12 KFP07712.1 - 0.1 12.5 0.5 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 Ribosomal L18ae/LX protein domain RRM_1 PF00076.17 KFP07713.1 - 2e-13 49.7 0.0 3.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07713.1 - 4.8e-10 39.2 0.0 7.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07713.1 - 4.5e-07 29.6 0.0 6.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KFP07714.1 - 1.1e-28 100.0 29.8 1.1e-28 100.0 20.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP07714.1 - 1.4e-07 30.4 33.6 0.00013 20.7 23.4 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KFP07714.1 - 1.2e-06 26.9 1.1 1.2e-06 26.9 0.8 3.3 2 2 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 KFP07714.1 - 0.0053 15.2 26.3 0.0073 14.7 2.6 2.7 1 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 KFP07715.1 - 1.7e-36 125.6 32.5 7.4e-36 123.5 19.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP07715.1 - 9.2e-14 50.8 25.6 1.4e-13 50.2 17.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KFP07715.1 - 2.1e-11 42.6 17.8 1.2e-05 23.6 1.0 3.9 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 KFP07715.1 - 4.1e-06 25.4 26.3 0.00029 19.3 5.5 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein VDE PF07137.6 KFP07718.1 - 0.089 12.6 0.8 7.5 6.3 0.3 2.0 1 1 0 2 2 2 0 Violaxanthin de-epoxidase (VDE) Glycos_transf_1 PF00534.15 KFP07720.1 - 7.4e-21 74.3 0.0 1e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFP07720.1 - 7.9e-12 45.4 0.0 2.7e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFP07720.1 - 1.7e-09 37.7 0.0 4.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 VDE PF07137.6 KFP07722.1 - 0.089 12.6 0.8 7.5 6.3 0.3 2.0 1 1 0 2 2 2 0 Violaxanthin de-epoxidase (VDE) MIF PF01187.13 KFP07723.1 - 2.1e-37 127.6 0.0 2.3e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Sugar_tr PF00083.19 KFP07724.1 - 2e-23 82.7 6.9 2.2e-23 82.5 4.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP07724.1 - 0.00017 20.4 11.8 0.0019 16.9 6.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Dimer_Tnp_hAT PF05699.9 KFP07724.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region TM231 PF10149.4 KFP07724.1 - 0.23 10.4 3.1 0.37 9.7 2.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 231 Sugar_tr PF00083.19 KFP07725.1 - 1.6e-45 155.5 4.4 1.8e-45 155.3 3.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP07725.1 - 4.9e-19 68.2 7.2 5.9e-19 67.9 5.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFP07725.1 - 0.046 12.1 11.4 0.022 13.1 5.0 2.2 1 1 1 3 3 3 0 MFS/sugar transport protein DER1 PF04511.10 KFP07726.1 - 1.2e-52 178.2 11.7 1.4e-52 178.0 8.1 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KFP07726.1 - 2.4 8.1 19.8 3.7 7.5 13.8 1.3 1 1 0 1 1 1 0 Rhomboid family SNF5 PF04855.7 KFP07727.1 - 3.4e-65 219.9 4.2 2.8e-63 213.6 1.4 2.7 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 DUF1679 PF07914.6 KFP07727.1 - 0.0035 16.0 0.0 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) CHCH PF06747.8 KFP07728.1 - 3.2e-06 26.9 5.3 4.2e-06 26.5 3.7 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 KFP07728.1 - 7.7e-06 26.1 0.3 8.7e-06 25.9 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Cmc1 PF08583.5 KFP07728.1 - 0.048 13.4 0.4 0.068 12.9 0.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Herpes_gE PF02480.11 KFP07728.1 - 0.093 10.9 0.0 0.096 10.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Gly-zipper_YMGG PF13441.1 KFP07728.1 - 0.8 9.2 7.7 1.1 8.7 5.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper V-set PF07686.12 KFP07729.1 - 1.3e-16 60.5 0.0 1.5e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain Ig_2 PF13895.1 KFP07729.1 - 0.0012 18.9 0.1 0.0016 18.5 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.20 KFP07729.1 - 0.0019 18.2 0.0 0.011 15.8 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP07729.1 - 0.0038 17.0 0.0 0.008 16.0 0.0 1.4 1 1 0 1 1 1 1 Immunoglobulin I-set domain Metallophos_2 PF12850.2 KFP07730.1 - 9.9e-18 64.4 0.0 1.2e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFP07730.1 - 0.00054 19.4 0.3 0.0019 17.6 0.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase V-set PF07686.12 KFP07731.1 - 3.8e-08 33.2 0.0 4.1e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain FKBP_C PF00254.23 KFP07731.1 - 0.00098 19.1 0.0 0.0012 18.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ig_3 PF13927.1 KFP07731.1 - 0.19 12.2 1.4 1.1 9.8 1.0 2.0 1 1 0 1 1 1 0 Immunoglobulin domain ig PF00047.20 KFP07731.1 - 0.2 11.8 2.0 0.79 9.8 1.4 1.9 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 KFP07732.1 - 9.4e-18 64.1 0.2 1e-17 64.0 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFP07732.1 - 5.1e-06 26.5 1.4 3.1e-05 24.0 0.9 1.9 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP07732.1 - 2.7e-05 23.9 0.0 0.00053 19.7 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP07732.1 - 0.00077 19.5 0.2 0.0015 18.6 0.1 1.4 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP07732.1 - 0.0015 18.9 2.8 0.0072 16.8 2.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP07733.1 - 1.7e-14 53.6 0.4 1.9e-14 53.5 0.3 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP07733.1 - 0.00068 19.4 0.0 0.0021 17.8 0.0 1.6 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 KFP07733.1 - 0.0008 19.4 1.5 0.0046 17.0 1.0 2.0 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP07733.1 - 0.0035 17.8 2.1 0.018 15.5 1.5 2.0 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP07734.1 - 1.6e-14 53.7 0.2 1.8e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP07734.1 - 0.0021 17.8 0.0 0.0057 16.4 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFP07734.1 - 0.013 15.6 0.4 0.028 14.5 0.3 1.7 1 1 0 1 1 1 0 Immunoglobulin domain Ig_3 PF13927.1 KFP07734.1 - 0.068 13.6 1.1 0.2 12.2 0.7 1.8 1 1 0 1 1 1 0 Immunoglobulin domain Big_2 PF02368.13 KFP07734.1 - 0.091 12.6 1.7 1.6 8.6 0.1 2.7 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 2) V-set PF07686.12 KFP07735.1 - 4.2e-09 36.3 0.0 4.5e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFP07735.1 - 0.026 14.6 0.5 0.062 13.4 0.4 1.6 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 KFP07736.1 - 2.9e-16 59.3 0.1 3.1e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP07736.1 - 9.6e-06 25.3 0.1 3e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.20 KFP07736.1 - 1e-05 25.5 0.4 2.2e-05 24.5 0.3 1.5 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP07736.1 - 0.00024 21.5 0.8 0.0007 20.0 0.6 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFP07736.1 - 0.00077 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP07737.1 - 1.2e-17 63.8 0.2 1.3e-17 63.7 0.2 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain ig PF00047.20 KFP07737.1 - 2.4e-05 24.3 1.8 0.00013 22.0 1.2 1.9 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.11 KFP07737.1 - 9e-05 22.2 0.0 0.0015 18.3 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.1 KFP07737.1 - 0.00018 21.9 2.9 0.0004 20.8 2.0 1.6 1 1 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.1 KFP07737.1 - 0.00024 21.1 0.1 0.00034 20.6 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain DUF2518 PF10726.4 KFP07737.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Protein of function (DUF2518) V-set PF07686.12 KFP07738.1 - 9.1e-09 35.2 0.0 9.9e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain TIG PF01833.19 KFP07738.1 - 0.024 14.6 1.5 0.83 9.6 0.0 2.2 1 1 1 2 2 2 0 IPT/TIG domain ig PF00047.20 KFP07738.1 - 0.1 12.7 0.5 0.18 11.9 0.4 1.6 1 1 0 1 1 1 0 Immunoglobulin domain V-set PF07686.12 KFP07739.1 - 4.7e-17 61.9 0.2 5.1e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP07739.1 - 9.5e-07 28.5 0.0 7.2e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain ig PF00047.20 KFP07739.1 - 2.8e-05 24.1 1.2 7.8e-05 22.7 0.8 1.7 1 1 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.1 KFP07739.1 - 0.0013 19.1 1.9 0.0058 17.1 1.3 1.9 1 1 0 1 1 1 1 Immunoglobulin domain TIG PF01833.19 KFP07739.1 - 0.0041 17.0 0.3 0.37 10.8 0.0 2.1 1 1 1 2 2 2 1 IPT/TIG domain Ig_2 PF13895.1 KFP07739.1 - 0.0045 17.0 0.1 0.0064 16.5 0.1 1.2 1 0 0 1 1 1 1 Immunoglobulin domain DNA_ligase_ZBD PF03119.11 KFP07739.1 - 0.15 11.7 0.1 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Carb_anhydrase PF00194.16 KFP07740.1 - 2.1e-65 220.2 0.0 2.3e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Lectin_C PF00059.16 KFP07741.1 - 2.8e-18 66.5 2.1 3.4e-18 66.2 0.6 1.8 2 0 0 2 2 2 1 Lectin C-type domain Ldl_recept_a PF00057.13 KFP07741.1 - 8.8e-11 41.5 7.9 8.8e-11 41.5 5.5 3.5 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A Herpes_UL45 PF05473.7 KFP07741.1 - 0.00098 18.5 0.4 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 UL45 protein Es2 PF09751.4 KFP07742.1 - 2.9e-96 323.4 1.1 2.9e-96 323.4 0.8 2.2 2 1 0 2 2 2 2 Nuclear protein Es2 RED_C PF07807.6 KFP07742.1 - 0.045 13.9 0.7 0.15 12.2 0.3 2.1 1 1 0 1 1 1 0 RED-like protein C-terminal region Homeobox PF00046.24 KFP07743.1 - 3.8e-22 77.6 5.3 5.9e-22 77.0 3.7 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP07743.1 - 0.015 14.9 0.1 0.039 13.6 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain HA PF03457.9 KFP07743.1 - 0.069 13.2 2.5 3.6 7.7 0.2 2.2 2 0 0 2 2 2 0 Helicase associated domain Myb_DNA-bind_3 PF12776.2 KFP07743.1 - 0.18 12.4 1.4 0.32 11.6 1.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain BatA PF07584.6 KFP07744.1 - 0.17 12.0 1.0 0.54 10.4 0.3 2.1 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal TSP_1 PF00090.14 KFP07745.1 - 1e-09 38.3 5.6 1e-09 38.3 3.9 2.2 2 1 1 3 3 3 1 Thrombospondin type 1 domain Somatomedin_B PF01033.12 KFP07745.1 - 3.5e-08 33.2 16.7 3.5e-08 33.2 11.6 2.4 2 1 0 2 2 2 1 Somatomedin B domain Mito_carr PF00153.22 KFP07746.1 - 9.6e-69 227.1 0.4 1.6e-22 79.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3748 PF12566.3 KFP07746.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Clathrin PF00637.15 KFP07747.1 - 2.4e-213 698.3 46.6 2.9e-34 117.7 3.8 8.0 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KFP07747.1 - 6.8e-44 145.1 0.9 9.7e-08 31.8 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KFP07747.1 - 3.5e-30 103.6 1.4 1e-29 102.2 0.2 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.5 KFP07747.1 - 1.6e-11 42.9 0.3 4.8e-11 41.4 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 KFP07747.1 - 6.5e-05 21.9 4.3 0.0014 17.5 0.1 3.9 3 1 2 5 5 5 1 Coatomer WD associated region TPR_7 PF13176.1 KFP07747.1 - 0.0072 16.0 12.2 0.7 9.8 0.2 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFP07747.1 - 0.028 15.0 18.7 63 4.6 0.3 9.5 9 1 2 11 11 11 0 Tetratricopeptide repeat SNARE PF05739.14 KFP07748.1 - 6.5e-11 41.7 14.1 8e-11 41.4 2.1 2.6 3 0 0 3 3 3 2 SNARE domain Fib_alpha PF08702.5 KFP07748.1 - 0.0036 17.4 6.1 0.079 13.0 0.1 2.2 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family IncA PF04156.9 KFP07748.1 - 0.0046 16.5 6.8 0.06 12.9 3.1 2.3 1 1 0 1 1 1 1 IncA protein DUF641 PF04859.7 KFP07748.1 - 0.018 14.8 3.9 0.88 9.3 0.1 2.5 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) COG5 PF10392.4 KFP07748.1 - 0.019 14.9 2.8 0.074 13.0 0.1 2.6 3 0 0 3 3 3 0 Golgi transport complex subunit 5 V-SNARE_C PF12352.3 KFP07748.1 - 0.024 14.6 5.8 0.066 13.2 0.4 3.0 3 1 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus SNAP-25 PF00835.14 KFP07748.1 - 0.035 14.8 0.3 0.095 13.4 0.2 1.8 1 0 0 1 1 1 0 SNAP-25 family DASH_Duo1 PF08651.5 KFP07748.1 - 0.051 13.1 1.9 0.57 9.7 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF745 PF05335.8 KFP07748.1 - 0.063 12.7 0.3 0.52 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.7 KFP07748.1 - 0.068 12.9 4.1 2.2 8.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF677 PF05055.7 KFP07748.1 - 0.13 10.8 4.4 2 7.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF677) FliJ PF02050.11 KFP07748.1 - 0.16 12.0 4.9 0.45 10.5 0.2 2.8 3 0 0 3 3 3 0 Flagellar FliJ protein KxDL PF10241.4 KFP07748.1 - 0.31 10.9 4.3 4.3 7.3 0.1 2.9 3 1 1 4 4 3 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.2 KFP07748.1 - 0.37 10.6 11.3 0.076 12.8 1.2 2.9 3 0 0 3 3 3 0 Tropomyosin like BLOC1_2 PF10046.4 KFP07748.1 - 0.49 10.5 8.3 2.9 8.0 2.1 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 KFP07748.1 - 0.71 8.4 6.7 2.7 6.5 3.6 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.7 KFP07748.1 - 0.72 10.2 5.5 14 6.1 0.5 3.1 3 1 1 4 4 4 0 SlyX Syntaxin_2 PF14523.1 KFP07748.1 - 0.83 9.7 6.9 3.4 7.7 1.3 2.2 2 0 0 2 2 2 0 Syntaxin-like protein Uds1 PF15456.1 KFP07748.1 - 1.2 9.1 7.2 16 5.4 2.6 2.9 2 1 0 2 2 2 0 Up-regulated During Septation WEMBL PF05701.6 KFP07748.1 - 2.2 6.6 7.9 0.46 8.8 2.8 1.7 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF722 PF05263.6 KFP07748.1 - 3.5 7.7 6.1 0.32 11.1 0.6 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF722) DUF3552 PF12072.3 KFP07748.1 - 4.4 6.4 7.0 17 4.5 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) PspA_IM30 PF04012.7 KFP07748.1 - 4.9 6.4 7.5 0.14 11.5 0.3 2.0 3 0 0 3 3 3 0 PspA/IM30 family ADIP PF11559.3 KFP07748.1 - 6.8 6.5 9.7 0.23 11.3 0.5 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding PI3_PI4_kinase PF00454.22 KFP07749.1 - 1.3e-39 136.0 0.2 1.3e-38 132.8 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFP07749.1 - 3.8e-33 114.2 0.0 9.3e-33 112.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ipi1_N PF12333.3 KFP07749.1 - 0.0078 16.1 0.5 0.36 10.8 0.1 3.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Serpin PF00079.15 KFP07750.1 - 1.4e-108 363.3 2.4 1.9e-108 362.9 1.6 1.1 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Pec_lyase_C PF00544.14 KFP07750.1 - 0.0098 15.3 0.2 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Pectate lyase BTB PF00651.26 KFP07751.1 - 6e-27 93.8 0.4 9.5e-27 93.1 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2 PF00096.21 KFP07751.1 - 2.4e-25 87.2 24.7 9e-06 25.7 0.8 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07751.1 - 4.9e-22 76.5 21.0 1.7e-05 24.7 0.2 5.7 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP07751.1 - 1.9e-21 75.2 29.5 2.5e-08 33.7 0.2 7.5 6 1 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP07751.1 - 3.8e-18 65.0 4.5 0.00032 20.7 0.2 5.9 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP07751.1 - 6.4e-12 45.2 14.1 0.0028 17.7 0.3 5.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP07751.1 - 5.5e-10 38.8 12.1 0.06 13.2 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-Di19 PF05605.7 KFP07751.1 - 0.00082 19.4 11.5 0.13 12.3 0.4 3.8 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFP07751.1 - 0.0017 18.4 14.8 5.6 7.1 0.1 5.2 1 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.14 KFP07751.1 - 0.013 15.6 5.9 7.3 6.7 0.0 3.7 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-BED PF02892.10 KFP07751.1 - 0.074 12.8 18.5 1.8 8.4 3.4 5.6 4 1 1 5 5 5 0 BED zinc finger LIM PF00412.17 KFP07751.1 - 0.1 12.6 0.4 0.1 12.6 0.3 3.4 2 1 1 3 3 2 0 LIM domain GAGA PF09237.6 KFP07751.1 - 0.11 12.1 4.1 1.3 8.6 0.1 3.1 2 1 1 3 3 3 0 GAGA factor C1_1 PF00130.17 KFP07751.1 - 0.14 11.8 7.4 0.42 10.3 0.8 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HYPF PF07503.7 KFP07751.1 - 0.62 9.5 8.0 4.4 6.7 0.6 3.3 3 1 0 3 3 3 0 HypF finger zf-AN1 PF01428.11 KFP07751.1 - 1.9 8.4 10.6 42 4.1 0.2 4.5 4 0 0 4 4 4 0 AN1-like Zinc finger zf-RING_5 PF14634.1 KFP07751.1 - 3.9 7.2 7.6 84 3.0 0.1 3.7 2 1 0 2 2 2 0 zinc-RING finger domain UQ_con PF00179.21 KFP07752.1 - 6.5e-43 145.5 0.3 7.2e-43 145.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP07752.1 - 2e-07 30.8 0.0 2.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFP07752.1 - 5.1e-05 22.9 0.1 8.8e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KFP07752.1 - 0.00016 21.5 0.8 0.0002 21.2 0.5 1.6 1 1 0 1 1 1 1 RWD domain YdjC PF04794.7 KFP07753.1 - 1.5e-16 60.6 0.0 1.7e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein MIR PF02815.14 KFP07754.1 - 8.9e-15 54.7 0.1 5.8e-12 45.5 0.0 2.3 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.6 KFP07754.1 - 0.033 13.2 0.0 0.066 12.2 0.0 1.4 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.1 KFP07754.1 - 0.053 13.9 0.3 0.48 10.8 0.1 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Topoisom_bac PF01131.15 KFP07755.1 - 4.5e-105 351.7 0.0 5.4e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KFP07755.1 - 1.3e-13 50.7 0.0 2.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF3628 PF12300.3 KFP07755.1 - 0.096 12.7 1.7 0.17 11.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) FXR1P_C PF12235.3 KFP07755.1 - 0.52 10.4 3.2 0.96 9.5 2.2 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Fer4_11 PF13247.1 KFP07755.1 - 1.5 8.7 11.4 0.15 12.0 4.4 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain PP2C PF00481.16 KFP07756.1 - 1.7e-66 224.2 0.0 2.1e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFP07756.1 - 0.0009 18.6 0.1 0.0032 16.8 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.20 KFP07757.1 - 3.1e-66 223.1 0.2 3.6e-66 222.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07757.1 - 5.7e-32 110.7 0.0 8.5e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP07757.1 - 0.00021 21.1 0.1 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YukC PF10140.4 KFP07757.1 - 0.011 14.3 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 KFP07757.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KFP07757.1 - 0.1 11.6 0.4 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFP07757.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Yippee-Mis18 PF03226.9 KFP07758.1 - 4.1e-18 65.2 0.3 5.4e-18 64.8 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.7 KFP07758.1 - 0.008 16.3 5.3 0.023 14.8 3.7 1.8 1 1 0 1 1 1 1 CHY zinc finger RIG-I_C-RD PF11648.3 KFP07758.1 - 0.11 12.4 0.4 0.21 11.4 0.3 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 KFP07758.1 - 0.29 11.0 3.8 0.48 10.3 0.5 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Pro_isomerase PF00160.16 KFP07759.1 - 1.1e-49 168.6 0.1 2.5e-49 167.4 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KFP07759.1 - 1.8e-06 27.3 0.1 1.8e-06 27.3 0.1 2.4 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 KFP07759.1 - 0.0012 18.7 0.0 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 1 U-box domain Hira PF07569.6 KFP07760.1 - 1.9e-58 197.2 0.1 5.2e-58 195.8 0.1 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KFP07760.1 - 2.9e-40 134.7 25.4 3.1e-09 36.3 3.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat HIRA_B PF09453.5 KFP07760.1 - 1e-08 34.4 0.1 2.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 HIRA B motif MRP-L28 PF09812.4 KFP07761.1 - 1.1e-49 168.3 7.0 1.2e-49 168.1 4.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PsiA PF06952.6 KFP07761.1 - 0.039 13.0 3.0 0.05 12.6 2.1 1.1 1 0 0 1 1 1 0 PsiA protein DUF4207 PF13904.1 KFP07761.1 - 6.5 6.0 12.8 14 4.9 8.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) UFD1 PF03152.9 KFP07762.1 - 2.8e-81 270.8 0.0 3.4e-81 270.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KFP07762.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 CDC45 PF02724.9 KFP07763.1 - 1e-181 605.1 14.2 1.2e-180 601.6 9.8 2.2 1 1 0 1 1 1 1 CDC45-like protein DUF4611 PF15387.1 KFP07763.1 - 0.3 11.2 4.2 0.69 10.0 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Septin PF00735.13 KFP07764.1 - 3.7e-123 410.0 0.0 4.6e-123 409.7 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFP07764.1 - 1.9e-07 31.0 0.0 4.1e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP07764.1 - 1.4e-05 24.6 0.0 0.0012 18.3 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KFP07764.1 - 3.7e-05 22.9 0.9 0.0001 21.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 KFP07764.1 - 5.9e-05 22.9 1.8 0.047 13.5 0.0 2.9 2 1 1 3 3 3 2 Dynamin family Ras PF00071.17 KFP07764.1 - 7e-05 22.2 0.0 0.00023 20.5 0.0 1.9 1 1 0 1 1 1 1 Ras family DUF258 PF03193.11 KFP07764.1 - 9.9e-05 21.5 0.1 0.00025 20.2 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFP07764.1 - 0.00034 20.7 0.1 0.002 18.2 0.0 2.3 2 2 1 3 3 3 1 AAA domain AAA_10 PF12846.2 KFP07764.1 - 0.0026 17.2 0.1 0.0032 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 KFP07764.1 - 0.0065 15.6 0.0 0.022 13.9 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFP07764.1 - 0.012 16.0 0.5 0.045 14.2 0.0 2.2 3 0 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 KFP07764.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFP07764.1 - 0.022 15.0 2.3 0.027 14.7 0.2 2.1 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KFP07764.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KFP07764.1 - 0.045 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF977 PF06163.6 KFP07764.1 - 0.09 12.5 0.7 0.76 9.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) AAA_23 PF13476.1 KFP07764.1 - 0.16 12.3 2.2 0.66 10.2 1.5 1.9 1 1 0 1 1 1 0 AAA domain Glyco_transf_6 PF03414.8 KFP07764.1 - 0.17 10.3 0.1 0.17 10.3 0.1 1.7 2 0 0 2 2 2 0 Glycosyltransferase family 6 FtsK_SpoIIIE PF01580.13 KFP07764.1 - 0.24 10.8 2.1 0.46 9.9 0.0 2.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 KFP07765.1 - 8e-128 425.3 0.4 9e-128 425.1 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFP07765.1 - 5.7e-07 29.5 0.1 1.1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP07765.1 - 1.7e-06 27.3 0.0 3.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFP07765.1 - 1.8e-05 24.2 0.1 0.0087 15.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KFP07765.1 - 0.00078 18.6 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 KFP07765.1 - 0.0018 18.1 2.4 0.15 11.9 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KFP07765.1 - 0.0024 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain Ras PF00071.17 KFP07765.1 - 0.0062 15.9 0.1 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.1 KFP07765.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFP07765.1 - 0.025 14.0 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFP07765.1 - 0.032 14.5 0.2 0.048 13.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KFP07765.1 - 0.046 13.8 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KFP07765.1 - 0.048 14.1 0.1 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KFP07765.1 - 0.055 12.9 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KFP07765.1 - 0.42 10.9 3.0 1.4 9.1 2.1 1.8 1 1 0 1 1 1 0 AAA domain LRR_8 PF13855.1 KFP07766.1 - 6.1e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRRNT PF01462.13 KFP07766.1 - 1.9e-05 24.0 1.6 1.9e-05 24.0 1.1 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 KFP07766.1 - 0.00013 21.4 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP07766.1 - 0.00096 18.8 0.4 0.097 12.7 0.1 2.9 2 0 0 2 2 2 1 Leucine Rich Repeat Foamy_virus_ENV PF03408.9 KFP07766.1 - 0.018 12.5 4.5 0.023 12.2 3.1 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein DUF948 PF06103.6 KFP07766.1 - 0.019 14.8 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tetraspannin PF00335.15 KFP07766.1 - 2.8 7.1 11.8 0.16 11.2 3.9 1.9 1 1 1 2 2 2 0 Tetraspanin family T-box PF00907.17 KFP07767.1 - 2.3e-69 232.5 0.5 2.9e-69 232.2 0.3 1.1 1 0 0 1 1 1 1 T-box WD40 PF00400.27 KFP07768.1 - 1.7e-26 91.0 5.4 1.7e-07 30.8 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 KFP07768.1 - 0.055 12.4 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pyr_redox_2 PF07992.9 KFP07769.1 - 2.4e-35 122.2 0.0 6.4e-35 120.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFP07769.1 - 1.1e-30 105.8 0.0 2.1e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFP07769.1 - 4.2e-13 49.5 0.4 8e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFP07769.1 - 2.5e-08 33.2 5.4 4.5e-07 29.0 0.6 3.1 2 2 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 KFP07769.1 - 2.4e-06 26.7 0.1 0.007 15.3 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KFP07769.1 - 1.4e-05 24.3 0.1 2.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KFP07769.1 - 6.5e-05 22.1 0.1 0.00012 21.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFP07769.1 - 7.3e-05 21.4 1.8 0.00071 18.1 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 KFP07769.1 - 0.00018 21.4 0.4 0.00051 20.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFP07769.1 - 0.00022 20.2 2.7 0.0011 17.9 1.8 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KFP07769.1 - 0.00061 19.9 0.3 0.0062 16.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFP07769.1 - 0.0025 16.7 1.3 0.0041 16.0 0.3 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase DUF1775 PF07987.6 KFP07769.1 - 0.0057 16.5 0.6 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unkown function (DUF1775) Nup35_RRM_2 PF14605.1 KFP07769.1 - 0.065 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Lycopene_cycl PF05834.7 KFP07769.1 - 0.082 11.8 1.0 0.35 9.7 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_3 PF01596.12 KFP07770.1 - 5.4e-24 84.3 0.0 7.1e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KFP07770.1 - 3.6e-14 53.4 0.0 5.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP07770.1 - 5.2e-08 33.4 0.0 8.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP07770.1 - 1.2e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KFP07770.1 - 5.3e-05 22.6 0.0 7.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_31 PF13847.1 KFP07770.1 - 0.00016 21.3 0.1 0.00036 20.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KFP07770.1 - 0.0005 19.6 0.0 0.00077 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 KFP07770.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GCD14 PF08704.5 KFP07770.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Arm PF00514.18 KFP07771.1 - 5.9e-37 124.2 2.4 9.7e-08 31.5 0.0 7.5 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFP07771.1 - 2.4e-16 59.7 0.7 2e-08 34.4 0.0 3.2 3 0 0 3 3 3 2 HEAT repeats Arm_2 PF04826.8 KFP07771.1 - 1.7e-09 37.1 0.2 0.00028 20.0 0.0 4.0 2 2 1 4 4 4 2 Armadillo-like HEAT PF02985.17 KFP07771.1 - 1.6e-08 33.9 0.8 0.5 10.5 0.1 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KFP07771.1 - 9.5e-08 32.3 2.4 0.37 11.3 0.1 5.8 6 0 0 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 KFP07771.1 - 0.022 14.4 0.0 0.11 12.1 0.0 2.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.1 KFP07771.1 - 0.13 12.1 0.1 0.7 9.8 0.0 2.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.2 KFP07771.1 - 0.14 12.0 0.1 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 NRDE PF05742.7 KFP07772.1 - 7.5e-10 38.5 0.0 7.8e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 NRDE protein dsrm PF00035.20 KFP07773.1 - 3.6e-20 72.2 3.7 3.5e-12 46.6 0.0 3.7 3 1 0 3 3 3 2 Double-stranded RNA binding motif WW PF00397.21 KFP07773.1 - 0.0019 17.9 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 WW domain Ran_BP1 PF00638.13 KFP07774.1 - 7.8e-55 184.1 0.4 7.8e-55 184.1 0.3 1.6 2 0 0 2 2 2 1 RanBP1 domain DUF1681 PF07933.9 KFP07774.1 - 0.0045 16.5 0.2 0.0066 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF883 PF05957.8 KFP07774.1 - 0.02 15.2 1.3 8.7 6.8 0.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) His_Phos_1 PF00300.17 KFP07775.1 - 2.2e-18 66.8 0.3 3e-17 63.1 0.2 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LEM PF03020.10 KFP07776.1 - 3.3e-09 36.0 0.4 1.1e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 LEM domain Ank_2 PF12796.2 KFP07776.1 - 3e-08 33.8 0.0 1.2e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP07776.1 - 1.6e-07 31.3 0.0 0.02 15.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP07776.1 - 2.2e-07 30.3 0.0 0.00045 19.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KFP07776.1 - 3.7e-06 26.6 0.0 0.0016 18.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 KFP07776.1 - 6.5e-06 26.5 0.1 4.2e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Cauli_VI PF01693.11 KFP07776.1 - 0.023 14.6 0.0 0.1 12.6 0.0 2.2 1 0 0 1 1 1 0 Caulimovirus viroplasmin Reo_sigmaC PF04582.7 KFP07777.1 - 5.4e-08 32.4 97.0 0.0015 17.7 5.0 9.1 2 1 5 8 8 8 7 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 KFP07777.1 - 0.0068 16.1 25.6 0.0068 16.1 17.7 13.6 4 2 10 15 15 15 4 TATA element modulatory factor 1 TATA binding PAD PF03068.10 KFP07778.1 - 0.0093 14.4 0.0 0.011 14.2 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) FHA PF00498.21 KFP07779.1 - 1.9e-15 56.7 0.1 4.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KFP07779.1 - 1.4e-07 31.2 13.9 1.4e-07 31.2 9.6 3.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.1 KFP07779.1 - 8.7e-07 28.5 13.7 8.7e-07 28.5 9.5 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP07779.1 - 4.3e-06 26.6 13.7 4.3e-06 26.6 9.5 4.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP07779.1 - 2.1e-05 24.0 13.2 2.1e-05 24.0 9.1 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP07779.1 - 0.00019 21.4 6.1 0.00019 21.4 4.2 3.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KFP07779.1 - 0.00049 19.8 9.0 0.00049 19.8 6.2 3.3 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KFP07779.1 - 0.0023 17.5 15.0 0.0023 17.5 10.4 3.8 3 0 0 3 3 3 1 zinc-RING finger domain Cnl2_NKP2 PF09447.5 KFP07779.1 - 0.039 13.6 0.4 1.2 8.8 0.1 2.7 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Auts2 PF15336.1 KFP07780.1 - 3e-117 390.1 13.5 3e-117 390.1 9.4 5.1 6 1 1 7 7 7 1 Autism susceptibility gene 2 protein Glycos_transf_2 PF00535.21 KFP07782.1 - 1.4e-23 83.4 0.2 2.8e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP07782.1 - 4.5e-18 65.4 0.0 7.5e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFP07782.1 - 9.1e-08 32.1 0.0 5.4e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFP07782.1 - 0.0001 21.7 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP07782.1 - 0.0092 15.0 0.0 0.016 14.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 CBF PF03914.12 KFP07783.1 - 8.2e-49 165.2 0.5 1.3e-48 164.5 0.3 1.4 1 0 0 1 1 1 1 CBF/Mak21 family SNF2_N PF00176.18 KFP07784.1 - 7.3e-55 185.8 3.2 1.7e-54 184.6 2.2 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 KFP07784.1 - 2.8e-25 87.8 10.6 2.8e-25 87.8 7.4 2.9 2 0 0 2 2 2 1 HSA Helicase_C PF00271.26 KFP07784.1 - 0.0016 18.2 0.0 0.0058 16.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 KFP07784.1 - 0.015 15.3 0.0 0.045 13.8 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain PseudoU_synth_1 PF01416.15 KFP07785.1 - 1.3e-23 83.4 0.0 1.7e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.20 KFP07787.1 - 2.1e-66 223.7 0.1 4.3e-66 222.7 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07787.1 - 5.6e-49 166.5 0.0 1e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 KFP07787.1 - 2.6e-46 157.7 6.2 4.7e-46 156.9 4.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.9 KFP07787.1 - 7.2e-06 25.2 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFP07787.1 - 5.4e-05 22.6 0.1 9.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KFP07787.1 - 0.0001 21.3 0.0 0.00095 18.2 0.0 2.4 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 KFP07787.1 - 0.014 15.1 0.0 0.17 11.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP07787.1 - 0.033 13.7 0.2 8.9 5.8 0.0 2.8 2 1 1 3 3 3 0 Choline/ethanolamine kinase Peptidase_M10 PF00413.19 KFP07788.1 - 1.2e-47 161.5 0.6 2.1e-47 160.6 0.4 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.14 KFP07788.1 - 5.2e-47 157.3 22.2 1.6e-13 50.1 0.2 5.1 5 0 0 5 5 5 4 Hemopexin PG_binding_1 PF01471.13 KFP07788.1 - 4.7e-14 52.0 0.1 1.1e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Astacin PF01400.19 KFP07788.1 - 0.041 13.2 1.1 0.63 9.3 0.6 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.4 KFP07788.1 - 0.055 12.3 0.1 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 DRY_EERY PF09750.4 KFP07789.1 - 1e-42 145.0 1.2 1e-42 145.0 0.8 5.1 5 1 1 6 6 6 1 Alternative splicing regulator Surp PF01805.15 KFP07789.1 - 1.2e-29 101.6 8.3 1.3e-14 53.5 0.6 2.5 2 0 0 2 2 2 2 Surp module 7tm_2 PF00002.19 KFP07790.1 - 9.4e-55 185.3 19.2 9.4e-55 185.3 13.3 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Laminin_G_3 PF13385.1 KFP07790.1 - 2.2e-16 60.4 0.2 4.3e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Dicty_CAR PF05462.6 KFP07790.1 - 1.2e-07 30.9 15.6 2e-07 30.1 10.8 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ras PF00071.17 KFP07791.1 - 5.3e-50 168.9 0.0 6.3e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP07791.1 - 1.9e-17 63.8 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP07791.1 - 1.2e-11 44.2 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KFP07791.1 - 0.00021 21.4 0.1 0.00078 19.5 0.1 1.8 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KFP07791.1 - 0.00041 19.5 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP07791.1 - 0.0014 18.0 0.5 0.022 14.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFP07791.1 - 0.0078 15.4 0.0 0.013 14.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFP07791.1 - 0.016 13.8 1.7 0.76 8.4 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 KFP07791.1 - 0.017 14.4 0.1 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.18 KFP07791.1 - 0.034 14.0 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.13 KFP07791.1 - 0.062 12.3 0.0 0.097 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 KFP07791.1 - 0.063 13.4 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KFP07791.1 - 0.067 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.20 KFP07792.1 - 2.2e-36 124.1 6.2 2.2e-36 124.1 4.3 2.4 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 KFP07792.1 - 6.1e-22 77.0 3.2 6.1e-22 77.0 2.2 3.2 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 KFP07792.1 - 9.6e-06 25.5 15.2 1.1e-05 25.3 5.2 2.8 1 1 1 2 2 2 1 Syntaxin-like protein COG5 PF10392.4 KFP07792.1 - 0.0017 18.2 6.7 0.32 10.9 0.6 2.7 2 1 0 2 2 2 2 Golgi transport complex subunit 5 Med28 PF11594.3 KFP07792.1 - 0.0026 17.9 7.2 0.24 11.6 0.7 2.4 1 1 0 2 2 2 2 Mediator complex subunit 28 UBN2 PF14223.1 KFP07792.1 - 0.013 15.2 0.8 0.013 15.2 0.5 2.9 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type Takusan PF04822.8 KFP07792.1 - 0.021 14.6 0.9 0.021 14.6 0.6 3.3 3 0 0 3 3 3 0 Takusan Baculo_PEP_C PF04513.7 KFP07792.1 - 0.04 13.7 2.6 0.38 10.5 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 KFP07792.1 - 0.041 13.4 12.0 0.33 10.4 0.9 2.4 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FH2 PF02181.18 KFP07792.1 - 0.05 12.4 12.9 0.15 10.8 1.3 2.7 2 1 1 3 3 3 0 Formin Homology 2 Domain DUF1264 PF06884.6 KFP07792.1 - 0.063 12.7 0.5 0.26 10.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1264) DUF3671 PF12420.3 KFP07792.1 - 0.068 13.1 1.5 0.13 12.2 0.1 2.1 2 0 0 2 2 1 0 Protein of unknown function Serine_rich PF08824.5 KFP07792.1 - 0.12 12.0 2.6 0.62 9.7 0.2 2.4 1 1 0 2 2 2 0 Serine rich protein interaction domain T2SF PF00482.18 KFP07792.1 - 0.13 12.1 4.8 0.25 11.2 0.4 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Internalin_N PF12354.3 KFP07792.1 - 0.14 11.8 0.9 0.26 10.9 0.6 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal AAA_13 PF13166.1 KFP07792.1 - 0.14 10.5 19.2 0.02 13.4 8.9 1.8 1 1 1 2 2 2 0 AAA domain DUF1845 PF08900.6 KFP07792.1 - 0.17 11.1 0.1 0.17 11.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1845) CENP-Q PF13094.1 KFP07792.1 - 0.17 11.8 14.5 2.4 8.1 2.7 3.1 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF342 PF03961.8 KFP07792.1 - 0.21 9.9 17.3 0.0049 15.3 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Prominin PF05478.6 KFP07792.1 - 0.27 8.7 11.3 0.032 11.8 0.6 2.2 1 1 0 2 2 2 0 Prominin DUF677 PF05055.7 KFP07792.1 - 0.36 9.4 17.2 0.021 13.5 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF677) Mur_ligase_M PF08245.7 KFP07792.1 - 0.5 10.3 5.6 0.4 10.6 0.4 2.6 2 1 0 2 2 2 0 Mur ligase middle domain DUF16 PF01519.11 KFP07792.1 - 0.75 10.0 16.8 0.24 11.6 0.9 2.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF713 PF05218.9 KFP07792.1 - 0.77 9.4 11.7 0.14 11.8 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF713) FlxA PF14282.1 KFP07792.1 - 0.77 9.7 6.6 0.68 9.9 1.7 2.4 2 0 0 2 2 2 0 FlxA-like protein DUF3708 PF12501.3 KFP07792.1 - 0.78 9.5 3.5 5.1 6.9 0.1 2.7 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter Syntaxin-6_N PF09177.6 KFP07792.1 - 0.8 10.1 12.5 0.08 13.3 1.5 3.2 2 2 1 3 3 3 0 Syntaxin 6, N-terminal GreA_GreB_N PF03449.10 KFP07792.1 - 0.82 9.7 7.0 0.32 11.0 0.3 3.1 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal CM_2 PF01817.16 KFP07792.1 - 0.89 9.6 10.2 0.13 12.4 1.2 3.0 3 1 0 3 3 2 0 Chorismate mutase type II Laminin_II PF06009.7 KFP07792.1 - 1 9.1 13.2 2.3 7.9 3.3 3.0 2 1 1 3 3 3 0 Laminin Domain II FlaC_arch PF05377.6 KFP07792.1 - 1.1 9.2 16.8 1.5 8.7 0.3 4.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Sec34 PF04136.10 KFP07792.1 - 1.1 8.9 8.7 0.12 12.0 2.0 2.1 1 1 0 2 2 2 0 Sec34-like family NPV_P10 PF05531.7 KFP07792.1 - 1.2 9.4 5.5 22 5.4 1.3 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Flu_NS2 PF00601.14 KFP07792.1 - 1.4 9.1 7.4 0.29 11.3 1.0 2.7 2 2 1 3 3 3 0 Influenza non-structural protein (NS2) Filo_VP35 PF02097.10 KFP07792.1 - 1.4 8.0 7.4 0.28 10.3 1.0 2.0 1 1 0 2 2 2 0 Filoviridae VP35 DUF479 PF04336.7 KFP07792.1 - 1.6 8.8 6.4 7.1 6.7 0.1 3.4 1 1 0 2 2 2 0 Protein of unknown function, DUF479 KIP1 PF07765.7 KFP07792.1 - 1.7 8.5 4.7 6.3 6.7 0.3 3.0 3 1 0 3 3 2 0 KIP1-like protein WXG100 PF06013.7 KFP07792.1 - 1.7 8.6 9.0 11 6.0 0.1 3.8 4 1 1 5 5 4 0 Proteins of 100 residues with WXG Allexi_40kDa PF05549.6 KFP07792.1 - 1.9 7.6 10.0 0.73 9.0 1.3 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein Spectrin PF00435.16 KFP07792.1 - 3.5 7.9 10.7 0.99 9.7 2.0 2.7 2 2 0 2 2 2 0 Spectrin repeat AAA_23 PF13476.1 KFP07792.1 - 3.7 7.8 17.4 7.1 6.9 2.8 2.1 1 1 1 2 2 2 0 AAA domain DUF904 PF06005.7 KFP07792.1 - 3.8 7.8 10.2 1.3 9.4 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DASH_Duo1 PF08651.5 KFP07792.1 - 3.9 7.1 9.2 5.4 6.6 0.2 3.7 3 1 0 3 3 3 0 DASH complex subunit Duo1 DUF2203 PF09969.4 KFP07792.1 - 4.5 7.5 13.0 3.9 7.7 2.6 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF848 PF05852.6 KFP07792.1 - 5.2 6.9 14.2 0.24 11.2 2.6 2.5 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4375 PF14300.1 KFP07792.1 - 5.2 7.0 7.2 15 5.5 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) TSC22 PF01166.13 KFP07792.1 - 5.9 6.9 9.0 4.1 7.4 0.0 2.9 3 0 0 3 3 2 0 TSC-22/dip/bun family ETRAMP PF09716.5 KFP07792.1 - 6.9 6.6 10.8 0.82 9.6 1.2 2.9 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF972 PF06156.8 KFP07792.1 - 8.1 6.8 17.4 0.38 11.1 3.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) GvpK PF05121.7 KFP07792.1 - 8.7 6.2 8.1 39 4.1 0.1 3.7 2 2 1 3 3 3 0 Gas vesicle protein K SH3_2 PF07653.12 KFP07793.1 - 4.2e-33 112.6 0.0 1.4e-10 40.4 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.1 KFP07793.1 - 1.4e-30 104.5 1.7 8.5e-13 47.6 0.1 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFP07793.1 - 1.9e-16 59.1 0.1 1.1e-06 27.9 0.0 4.2 3 1 0 3 3 3 3 SH3 domain fn3 PF00041.16 KFP07793.1 - 2.2e-13 50.1 5.5 9.8e-05 22.4 0.2 4.1 3 1 0 3 3 3 3 Fibronectin type III domain ADIP PF11559.3 KFP07793.1 - 1.2 8.9 12.6 2.5 7.9 8.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1423 PF07227.6 KFP07793.1 - 1.4 7.4 6.9 2.2 6.8 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Piwi PF02171.12 KFP07794.1 - 6.4e-107 357.0 0.0 9.9e-107 356.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFP07794.1 - 7.3e-38 128.9 0.0 1.3e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Frizzled PF01534.12 KFP07795.1 - 3.3e-143 476.4 21.7 4.1e-143 476.0 15.1 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 KFP07795.1 - 2.2e-35 121.5 8.8 5.3e-35 120.2 6.1 1.7 1 0 0 1 1 1 1 Fz domain MEF2_binding PF09047.5 KFP07796.1 - 2.6e-22 78.1 7.5 6.2e-22 76.9 5.2 1.7 1 0 0 1 1 1 1 MEF2 binding TPR_11 PF13414.1 KFP07796.1 - 1.2e-14 53.7 18.3 3.2e-07 29.9 0.0 8.0 7 1 1 8 8 8 3 TPR repeat TPR_2 PF07719.12 KFP07796.1 - 1.7e-08 33.7 24.2 0.18 11.8 0.1 8.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFP07796.1 - 3.2e-05 23.7 9.1 9.9 6.6 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFP07796.1 - 3.3e-05 23.2 25.4 0.064 12.8 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP07796.1 - 0.00012 21.9 11.2 0.16 11.9 0.2 5.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP07796.1 - 0.057 14.0 3.4 7.5 7.4 0.2 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFP07796.1 - 0.12 13.0 11.7 35 5.2 0.2 6.4 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFP07796.1 - 0.45 11.0 2.1 25 5.6 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFP07796.1 - 1.3 8.9 9.2 1.9 8.4 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat T-box PF00907.17 KFP07797.1 - 2e-89 297.9 0.6 2.7e-89 297.5 0.4 1.2 1 0 0 1 1 1 1 T-box SH3_2 PF07653.12 KFP07798.1 - 1.1e-23 82.5 0.2 4.7e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.19 KFP07798.1 - 2.6e-21 75.1 0.0 4.7e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.23 KFP07798.1 - 4.2e-21 74.0 0.3 4.8e-16 57.8 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KFP07798.1 - 1.7e-18 65.9 0.1 8.7e-11 41.2 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain mit_SMPDase PF14724.1 KFP07799.1 - 0 1537.3 3.9 0 1537.1 2.7 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase G_glu_transpept PF01019.16 KFP07800.1 - 8.8e-173 575.4 0.0 1e-172 575.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase LSM PF01423.17 KFP07801.1 - 2.2e-13 49.5 0.2 3e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Kringle PF00051.13 KFP07801.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Kringle domain Guanylate_cyc_2 PF09778.4 KFP07802.1 - 3.7e-94 313.8 8.1 4.2e-94 313.6 5.6 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.1 KFP07802.1 - 1.2e-11 45.1 0.1 3.6e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase_C39 like family DUF3335 PF11814.3 KFP07802.1 - 0.00012 21.2 0.2 0.12 11.4 0.1 2.3 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.10 KFP07802.1 - 0.00031 20.5 0.1 0.004 16.9 0.1 2.4 2 1 0 2 2 2 1 Peptidase C39 family Peptidase_C70 PF12385.3 KFP07802.1 - 0.02 14.5 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 TMEM52 PF14979.1 KFP07802.1 - 0.028 14.3 3.4 0.05 13.4 2.4 1.5 1 0 0 1 1 1 0 Transmembrane 52 Doppel PF11466.3 KFP07802.1 - 0.047 13.2 0.3 0.1 12.1 0.2 1.6 1 0 0 1 1 1 0 Prion-like protein Doppel CN_hydrolase PF00795.17 KFP07803.1 - 6.6e-40 136.4 0.2 8.6e-40 136.0 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase 7tm_1 PF00001.16 KFP07804.1 - 1.1e-52 178.8 17.0 1.2e-52 178.5 11.8 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP07804.1 - 9e-08 31.5 20.4 1.3e-06 27.7 14.1 2.1 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.4 KFP07804.1 - 0.024 13.7 25.5 0.15 11.1 17.7 2.2 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Ni_hydr_CYTB PF01292.15 KFP07804.1 - 2.7 7.3 9.7 0.029 13.7 0.6 2.1 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 CH PF00307.26 KFP07805.1 - 6.9e-22 77.5 0.1 4e-21 75.0 0.1 2.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP07805.1 - 1.2e-07 31.2 0.0 3.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain TPR_MLP1_2 PF07926.7 KFP07805.1 - 0.0018 18.0 11.4 0.0018 18.0 7.9 6.7 3 1 2 5 5 5 1 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 KFP07805.1 - 0.13 10.7 88.2 0.26 9.6 50.1 3.3 2 1 0 2 2 2 0 Weak chloroplast movement under blue light RhoGAP PF00620.22 KFP07806.1 - 5.5e-50 168.9 0.2 8.9e-49 165.0 0.0 2.6 2 0 0 2 2 2 1 RhoGAP domain Bcr-Abl_Oligo PF09036.5 KFP07806.1 - 2.3e-45 152.4 0.6 7.9e-45 150.7 0.4 2.0 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain RhoGEF PF00621.15 KFP07806.1 - 2.2e-36 125.4 0.9 4.4e-36 124.4 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain C2 PF00168.25 KFP07806.1 - 4.2e-10 39.3 0.0 1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain PH PF00169.24 KFP07806.1 - 2.5e-08 34.0 0.3 9.3e-08 32.2 0.2 2.0 1 0 0 1 1 1 1 PH domain Ras PF00071.17 KFP07807.1 - 1.6e-44 151.1 0.1 2.1e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP07807.1 - 2.7e-17 63.3 0.0 4.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP07807.1 - 2.2e-15 56.3 0.0 3.1e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP07807.1 - 5.4e-06 25.7 0.0 6.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP07807.1 - 9.9e-06 25.4 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP07807.1 - 0.00024 20.5 0.0 0.0042 16.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFP07807.1 - 0.0044 16.2 0.0 0.057 12.6 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 KFP07807.1 - 0.021 14.5 0.0 0.073 12.7 0.0 1.8 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFP07807.1 - 0.05 13.0 0.0 2.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KFP07807.1 - 0.054 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain HEAT_2 PF13646.1 KFP07808.1 - 4.1e-15 55.8 7.7 7.7e-07 29.3 0.6 4.0 1 1 4 5 5 5 5 HEAT repeats Arm PF00514.18 KFP07808.1 - 2.7e-11 42.8 12.6 0.0007 19.3 0.0 7.4 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KFP07808.1 - 2.3e-10 39.4 1.3 9.3e-09 34.1 0.6 2.3 1 1 1 2 2 2 2 Adaptin N terminal region HEAT PF02985.17 KFP07808.1 - 3.9e-10 38.9 6.3 0.049 13.7 0.0 6.2 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KFP07808.1 - 2.1e-06 28.0 8.7 0.07 13.6 1.4 5.7 3 2 2 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 KFP07808.1 - 3.9e-05 23.5 0.6 1.2 8.9 0.0 4.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KFP07808.1 - 5e-05 21.7 2.2 0.008 14.4 0.7 2.8 1 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 KFP07808.1 - 0.00018 20.9 4.2 1.1 8.5 0.0 4.5 1 1 3 4 4 4 2 CLASP N terminal DUF2435 PF10363.4 KFP07808.1 - 0.016 15.0 0.8 3.1 7.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) G-alpha PF00503.15 KFP07809.1 - 7.1e-128 426.5 1.8 8.5e-128 426.3 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFP07809.1 - 9.2e-17 60.8 0.3 6.4e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP07809.1 - 0.00069 18.8 6.0 0.023 13.8 0.4 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP07809.1 - 0.0017 18.3 0.1 0.31 10.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KFP07809.1 - 0.0099 15.3 0.1 0.03 13.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.6 KFP07809.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DUF2951 PF11166.3 KFP07809.1 - 0.021 14.6 1.9 0.32 10.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Miro PF08477.8 KFP07809.1 - 0.12 12.8 2.2 6.6 7.2 0.2 2.9 3 0 0 3 3 3 0 Miro-like protein SSF PF00474.12 KFP07810.1 - 4.9e-167 555.6 24.9 8.2e-167 554.9 17.2 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family 14-3-3 PF00244.15 KFP07811.1 - 1.7e-97 325.1 8.2 1.9e-97 325.0 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Homeobox PF00046.24 KFP07812.1 - 1.8e-10 40.2 1.5 5e-10 38.8 1.0 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP07812.1 - 2.6e-06 27.0 0.2 9.8e-06 25.1 0.2 2.0 1 0 0 1 1 1 1 Homeobox KN domain CENP-B_N PF04218.8 KFP07812.1 - 0.09 12.2 0.1 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_OrfB_IS605 PF12323.3 KFP07812.1 - 0.53 9.6 3.0 4 6.8 2.1 2.3 1 1 0 1 1 1 0 Helix-turn-helix domain DUF3608 PF12257.3 KFP07813.1 - 7e-60 202.3 0.3 1.1e-59 201.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KFP07813.1 - 7e-11 41.7 0.0 1.6e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Las1 PF04031.8 KFP07813.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Las1-like DUF3375 PF11855.3 KFP07813.1 - 0.013 14.2 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Tantalus PF15386.1 KFP07814.1 - 7.9e-28 96.0 3.2 2.2e-27 94.5 2.2 1.8 1 0 0 1 1 1 1 Drosophila Tantalus-like Transferrin PF00405.12 KFP07815.1 - 7.7e-149 495.0 2.4 1e-80 271.1 0.1 2.3 2 1 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.2 KFP07815.1 - 2.5e-07 30.3 0.0 0.027 13.8 0.0 2.8 3 0 0 3 3 3 2 ABC transporter, phosphonate, periplasmic substrate-binding protein PS_Dcarbxylase PF02666.10 KFP07816.1 - 6.3e-74 247.6 0.0 7.9e-74 247.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase TGS PF02824.16 KFP07817.1 - 3.7e-24 84.3 0.2 8.1e-24 83.2 0.0 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 KFP07817.1 - 1.8e-17 63.3 0.1 4.7e-17 62.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP07817.1 - 6e-11 41.8 0.0 8.3e-10 38.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFP07817.1 - 0.00059 19.3 0.1 0.52 9.7 0.0 3.6 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFP07817.1 - 0.0011 18.8 0.4 1.6 8.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KFP07817.1 - 0.0042 15.9 0.5 0.02 13.6 0.1 2.0 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KFP07817.1 - 0.021 15.3 0.0 0.059 13.8 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 KFP07817.1 - 0.085 12.8 0.2 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain zf-C2H2_4 PF13894.1 KFP07818.1 - 2.5e-35 118.1 44.6 2.5e-05 24.2 0.0 8.5 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 KFP07818.1 - 1.3e-31 107.0 46.4 4.4e-05 23.5 0.6 8.5 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP07818.1 - 4.2e-19 67.8 58.7 7e-07 29.2 1.5 10.4 11 0 0 11 11 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFP07818.1 - 2.2e-14 53.0 30.6 0.0013 18.8 0.4 8.3 7 1 1 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP07818.1 - 1.1e-11 44.5 30.0 0.029 14.5 0.4 8.1 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP07818.1 - 0.00014 21.8 29.9 0.16 12.1 0.9 5.9 4 2 2 6 6 6 5 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFP07818.1 - 0.0038 17.0 37.7 0.019 14.8 0.9 7.9 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFP07818.1 - 0.027 14.5 27.0 36 4.5 5.2 7.3 3 1 4 7 7 7 0 C2H2 type zinc-finger (2 copies) ROS_MUCR PF05443.6 KFP07818.1 - 0.03 14.0 1.0 5.9 6.6 0.0 2.9 2 1 1 3 3 3 0 ROS/MUCR transcriptional regulator protein XPA_N PF01286.13 KFP07818.1 - 0.1 12.3 0.0 0.1 12.3 0.0 6.4 8 0 0 8 8 7 0 XPA protein N-terminal ARS2 PF04959.8 KFP07818.1 - 0.33 11.1 4.1 2.2 8.4 0.1 3.3 2 1 1 3 3 3 0 Arsenite-resistance protein 2 GAGA PF09237.6 KFP07818.1 - 0.41 10.2 22.1 4.2 7.0 0.3 6.2 6 1 1 7 7 7 0 GAGA factor DUF629 PF04780.7 KFP07818.1 - 0.66 8.4 8.8 1.5 7.2 0.7 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF629) AT_hook PF02178.14 KFP07818.1 - 8.4 6.4 13.5 0.069 12.8 2.8 2.4 2 0 0 2 2 2 0 AT hook motif Kringle PF00051.13 KFP07819.1 - 8.2e-08 32.2 1.2 1.6e-07 31.2 0.9 1.5 1 0 0 1 1 1 1 Kringle domain SDF PF00375.13 KFP07819.1 - 0.054 12.2 0.0 0.065 11.9 0.0 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family TMEM154 PF15102.1 KFP07819.1 - 0.071 12.8 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2678 PF10856.3 KFP07819.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Pkinase_Tyr PF07714.12 KFP07820.1 - 6.8e-51 172.8 0.0 1.5e-50 171.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP07820.1 - 4.7e-49 166.8 0.0 7.3e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.17 KFP07820.1 - 1.7e-26 92.0 18.8 1.1e-16 60.5 3.5 2.6 2 0 0 2 2 2 2 LIM domain PDZ PF00595.19 KFP07820.1 - 2.4e-15 56.4 0.0 4.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Kdo PF06293.9 KFP07820.1 - 0.00027 20.0 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP07820.1 - 0.007 16.1 0.1 0.024 14.3 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family PDZ_2 PF13180.1 KFP07820.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain RRN7 PF11781.3 KFP07820.1 - 0.6 9.6 10.2 0.18 11.3 2.1 2.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C3HC4_2 PF13923.1 KFP07821.1 - 1.5e-10 40.9 9.0 2e-10 40.5 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP07821.1 - 1.5e-10 40.5 7.5 2.1e-10 40.0 5.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP07821.1 - 2.6e-10 39.7 5.1 3.7e-10 39.2 3.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP07821.1 - 1.4e-09 37.6 9.4 1.9e-09 37.1 6.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFP07821.1 - 1.1e-07 31.4 6.5 1.6e-07 30.9 4.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFP07821.1 - 5.5e-06 25.9 4.8 4.4e-05 23.0 1.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 KFP07821.1 - 6.9e-05 22.6 2.6 0.0001 22.0 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFP07821.1 - 0.00011 22.0 7.7 0.00016 21.4 5.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 KFP07821.1 - 0.00051 19.7 2.8 0.00078 19.1 1.9 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 KFP07821.1 - 0.0022 18.0 9.4 0.004 17.2 6.5 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 KFP07821.1 - 0.0061 15.7 0.1 0.0077 15.4 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.1 KFP07821.1 - 0.018 14.5 5.4 0.038 13.5 3.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 KFP07821.1 - 0.047 13.4 1.5 0.1 12.3 0.9 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.1 KFP07821.1 - 0.054 13.0 4.6 0.25 10.9 3.2 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TerY-C PF15616.1 KFP07821.1 - 0.68 9.8 3.6 1 9.3 2.5 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 KFP07821.1 - 1.8 8.5 8.8 31 4.5 6.3 2.4 1 1 1 2 2 2 0 IBR domain DUF1272 PF06906.6 KFP07821.1 - 2.5 7.9 5.8 14 5.6 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Peptidase_A22B PF04258.8 KFP07823.1 - 1.5e-96 323.3 10.7 1.9e-96 323.0 7.4 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Acyl-CoA_dh_1 PF00441.19 KFP07824.1 - 1.8e-52 177.4 6.6 2.7e-52 176.8 4.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFP07824.1 - 9.1e-38 129.3 0.3 3e-37 127.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFP07824.1 - 3.2e-24 85.6 3.8 5.5e-24 84.9 2.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFP07824.1 - 3.8e-18 64.7 1.9 7.3e-18 63.8 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain GMP_PDE_delta PF05351.6 KFP07825.1 - 1.6e-78 261.9 1.6 1.8e-78 261.7 1.1 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Malectin PF11721.3 KFP07826.1 - 2.5e-36 125.0 0.2 2.5e-36 125.0 0.1 1.4 2 0 0 2 2 2 1 Di-glucose binding within endoplasmic reticulum EF-hand_1 PF00036.27 KFP07827.1 - 3.5e-31 104.1 15.4 2.4e-10 38.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KFP07827.1 - 2.3e-25 86.1 6.1 5.7e-09 35.1 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KFP07827.1 - 2.3e-24 85.3 8.1 6.9e-16 58.1 0.9 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFP07827.1 - 2.6e-21 74.9 13.0 1.9e-13 49.8 0.4 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KFP07827.1 - 2.9e-21 73.7 12.5 2e-08 33.2 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KFP07827.1 - 4.5e-09 36.1 0.1 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFP07827.1 - 2.6e-05 24.1 0.9 0.0021 18.0 0.0 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 KFP07827.1 - 0.0013 18.4 0.3 1 9.1 0.0 2.5 2 1 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_4 PF12763.2 KFP07827.1 - 0.002 17.8 1.3 0.042 13.5 0.1 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand POTRA_2 PF08479.6 KFP07827.1 - 0.0046 16.5 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 POTRA domain, ShlB-type DUF4375 PF14300.1 KFP07827.1 - 0.072 13.0 0.3 0.79 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) FliG_N PF14842.1 KFP07827.1 - 0.1 12.7 0.2 0.95 9.5 0.0 2.3 3 0 0 3 3 3 0 FliG N-terminal domain Dockerin_1 PF00404.13 KFP07827.1 - 0.16 11.7 9.8 1.8 8.4 0.9 3.5 3 0 0 3 3 3 0 Dockerin type I repeat EFhand_Ca_insen PF08726.5 KFP07827.1 - 0.34 10.9 1.4 3.5 7.6 0.1 2.7 2 2 0 2 2 2 0 Ca2+ insensitive EF hand RNase_P_Rpp14 PF01900.14 KFP07828.1 - 1e-27 96.1 0.1 1.6e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family Dynein_light PF01221.13 KFP07829.1 - 1.7e-46 156.1 1.5 1.9e-46 155.9 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.24 KFP07829.1 - 0.0039 16.3 0.1 0.0046 16.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ground-like PF04155.13 KFP07829.1 - 0.037 14.3 0.2 0.052 13.8 0.1 1.4 1 1 0 1 1 1 0 Ground-like domain CotJB PF12652.2 KFP07829.1 - 0.089 12.8 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 CotJB protein TraH PF06122.6 KFP07829.1 - 0.1 11.3 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Imm28 PF15574.1 KFP07829.1 - 0.11 12.0 0.3 0.18 11.3 0.2 1.5 1 1 0 1 1 1 0 Immunity protein 28 SpoIIIAH PF12685.2 KFP07829.1 - 0.44 10.0 3.0 0.57 9.6 2.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Ubie_methyltran PF01209.13 KFP07830.1 - 1.7e-90 302.1 0.0 2.1e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFP07830.1 - 1.3e-17 64.0 0.0 2.8e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP07830.1 - 1.1e-15 57.4 0.0 3.6e-14 52.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP07830.1 - 2.7e-11 43.7 0.0 6.1e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP07830.1 - 2.1e-08 34.5 0.0 1.5e-07 31.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP07830.1 - 4e-08 33.8 0.0 4.2e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP07830.1 - 1.6e-07 31.1 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP07830.1 - 4e-07 30.0 0.0 7.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFP07830.1 - 0.0055 16.3 0.0 0.021 14.4 0.0 2.0 3 0 0 3 3 3 1 Hypothetical methyltransferase UPF0020 PF01170.13 KFP07830.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Dynein_light PF01221.13 KFP07831.1 - 6.9e-46 154.1 1.4 7.5e-46 154.0 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.24 KFP07831.1 - 0.01 14.9 0.1 0.012 14.7 0.1 1.0 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ground-like PF04155.13 KFP07831.1 - 0.036 14.3 0.2 0.055 13.7 0.1 1.4 1 1 0 1 1 1 0 Ground-like domain CotJB PF12652.2 KFP07831.1 - 0.087 12.9 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 CotJB protein TraH PF06122.6 KFP07831.1 - 0.099 11.4 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Glu-tRNAGln PF02686.10 KFP07832.1 - 1.2e-15 57.0 0.1 2.8e-15 55.8 0.1 1.6 1 1 1 2 2 2 1 Glu-tRNAGln amidotransferase C subunit UPF0203 PF05254.7 KFP07833.1 - 2.2e-27 94.6 0.3 2.4e-27 94.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 KFP07833.1 - 0.0068 16.2 1.6 1.6 8.7 0.1 2.3 2 0 0 2 2 2 2 CHCH domain COX17 PF05051.8 KFP07833.1 - 0.069 13.1 0.5 0.18 11.8 0.3 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.12 KFP07833.1 - 0.082 12.9 2.7 0.15 12.1 1.9 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 KFP07833.1 - 0.087 12.7 1.6 0.97 9.4 1.2 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6A PF02046.10 KFP07834.1 - 2.9e-27 94.9 0.0 3.1e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RRM_1 PF00076.17 KFP07835.1 - 2.6e-33 113.4 2.4 3.5e-17 61.7 0.6 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07835.1 - 2.2e-28 98.0 1.3 1.4e-14 53.8 0.3 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07835.1 - 3.8e-13 49.0 0.8 4.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 KFP07835.1 - 0.0017 18.3 0.4 0.82 9.7 0.0 2.3 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) Med8 PF10232.4 KFP07835.1 - 0.053 13.0 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CSD PF00313.17 KFP07835.1 - 0.12 12.1 1.0 2.6 7.8 0.2 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DUF2136 PF09907.4 KFP07835.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) Phospholip_A2_1 PF00068.14 KFP07836.1 - 1e-42 145.0 16.6 1.2e-42 144.8 11.5 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFP07836.1 - 0.0072 16.0 0.0 0.013 15.3 0.0 1.5 1 1 0 1 1 1 1 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.7 KFP07836.1 - 1.1 9.2 14.1 33 4.5 9.7 2.2 1 1 0 1 1 1 0 Phospholipase A2 SIR2 PF02146.12 KFP07837.1 - 5.7e-52 176.0 0.0 7.8e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-C3HC4_3 PF13920.1 KFP07837.1 - 0.14 11.8 0.3 0.14 11.8 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L10 PF00466.15 KFP07838.1 - 7.4e-24 83.5 0.0 2.2e-23 82.0 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KFP07838.1 - 2.7e-21 75.7 7.1 2.7e-21 75.7 4.9 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein DEC-1_N PF04625.8 KFP07838.1 - 0.16 10.6 6.0 0.69 8.5 2.9 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF3554 PF12074.3 KFP07839.1 - 6.1e-74 249.4 17.3 2.3e-72 244.2 2.8 6.3 6 1 1 7 7 7 2 Domain of unknown function (DUF3554) HEAT PF02985.17 KFP07839.1 - 7.5e-51 165.6 40.3 0.0039 17.1 0.0 25.9 29 0 0 29 29 29 13 HEAT repeat HEAT_2 PF13646.1 KFP07839.1 - 3.5e-50 168.2 50.1 2e-08 34.3 0.2 19.2 12 3 5 19 19 19 10 HEAT repeats HEAT_EZ PF13513.1 KFP07839.1 - 6.2e-31 106.0 49.8 0.0021 18.4 0.0 22.9 17 7 10 27 27 27 10 HEAT-like repeat CLASP_N PF12348.3 KFP07839.1 - 4.4e-21 75.2 6.3 3.4e-05 23.3 0.0 10.8 9 2 1 11 11 11 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 KFP07839.1 - 9.5e-17 61.1 0.0 0.25 11.7 0.0 10.1 10 1 2 12 12 12 5 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFP07839.1 - 1.9e-11 44.1 3.3 0.63 9.8 0.0 9.3 8 1 1 9 9 9 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 KFP07839.1 - 3.4e-06 27.0 7.3 2.3 8.0 0.0 7.8 9 0 0 9 9 9 2 Parkin co-regulated protein Ras PF00071.17 KFP07840.1 - 2.6e-55 186.2 0.5 3.4e-55 185.8 0.4 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP07840.1 - 2.1e-16 60.5 0.2 4.8e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFP07840.1 - 7.4e-16 57.8 0.2 1e-15 57.4 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP07840.1 - 1.4e-07 31.1 0.1 2.4e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP07840.1 - 0.0037 16.4 0.8 0.0087 15.2 0.6 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP07840.1 - 0.0061 16.5 0.3 0.0094 15.8 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase bZIP_2 PF07716.10 KFP07841.1 - 0.044 13.6 1.6 0.044 13.6 1.1 8.3 5 3 5 10 10 10 0 Basic region leucine zipper DUF1601 PF07671.6 KFP07841.1 - 0.057 13.0 4.5 2.9 7.6 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) bZIP_1 PF00170.16 KFP07841.1 - 1.3 9.0 42.3 0.51 10.3 1.1 6.6 5 3 2 7 7 7 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 KFP07841.1 - 3.9 7.3 75.8 4.8 7.0 13.3 5.3 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CNH PF00780.17 KFP07842.1 - 5.2e-60 203.1 0.0 1.1e-59 202.0 0.0 1.6 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.20 KFP07842.1 - 1.9e-57 194.3 0.0 1.9e-57 194.3 0.0 3.0 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07842.1 - 9e-29 100.3 0.0 2.5e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KFP07842.1 - 9e-06 25.3 9.3 2.1e-05 24.1 6.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFP07842.1 - 0.00018 21.6 0.0 0.00073 19.7 0.0 2.2 1 0 0 1 1 1 1 PH domain V_ATPase_I PF01496.14 KFP07842.1 - 0.00063 17.7 13.9 0.00063 17.7 9.6 5.6 1 1 4 5 5 5 1 V-type ATPase 116kDa subunit family Seadorna_VP7 PF07387.6 KFP07842.1 - 0.00076 18.4 0.0 0.0025 16.7 0.0 1.9 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_C PF00433.19 KFP07842.1 - 0.00099 19.5 1.2 0.0029 18.1 0.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 KFP07842.1 - 0.0056 16.4 0.0 0.0056 16.4 0.0 4.4 5 2 1 6 6 6 1 Phosphotransferase enzyme family AMPKBI PF04739.10 KFP07843.1 - 1.1e-29 102.2 0.3 1.8e-29 101.5 0.2 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain CBM_48 PF02922.13 KFP07843.1 - 0.057 13.4 0.1 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Dispanin PF04505.7 KFP07844.1 - 3.5e-22 77.7 0.7 6.1e-22 76.9 0.2 1.5 1 1 1 2 2 2 1 Interferon-induced transmembrane protein DUF4190 PF13828.1 KFP07844.1 - 0.0015 17.9 4.3 0.0072 15.8 3.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) Claudin_3 PF06653.6 KFP07844.1 - 0.015 15.0 1.1 0.018 14.7 0.7 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF4234 PF14018.1 KFP07844.1 - 0.23 11.2 3.0 1.7 8.4 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) Homeobox PF00046.24 KFP07847.1 - 7.4e-23 79.9 8.1 1.5e-22 78.9 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP07847.1 - 0.033 13.8 0.6 0.033 13.8 0.4 1.9 2 0 0 2 2 2 0 Homeobox KN domain DUF2209 PF09974.4 KFP07847.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Homeobox PF00046.24 KFP07848.1 - 1.1e-21 76.1 7.9 2.1e-21 75.2 5.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP07848.1 - 0.01 15.5 1.7 0.026 14.2 1.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain Hox9_act PF04617.8 KFP07849.1 - 2.3e-58 197.3 0.2 3.4e-58 196.8 0.1 1.2 1 0 0 1 1 1 1 Hox9 activation region Homeobox PF00046.24 KFP07849.1 - 2.6e-21 74.9 6.2 4.2e-21 74.3 4.3 1.3 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 KFP07849.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFP07850.1 - 9.2e-22 76.4 5.9 2.6e-21 74.9 4.1 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP07850.1 - 0.054 13.2 0.4 0.054 13.2 0.3 2.6 3 0 0 3 3 3 0 Homeobox KN domain DUF3528 PF12045.3 KFP07851.1 - 3e-55 186.3 3.2 5.3e-55 185.5 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) Homeobox PF00046.24 KFP07851.1 - 5.5e-20 70.7 8.1 1.1e-19 69.7 5.6 1.5 1 0 0 1 1 1 1 Homeobox domain Baculo_p74_N PF08404.5 KFP07851.1 - 0.011 14.5 0.2 0.016 13.9 0.2 1.3 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Homeobox_KN PF05920.6 KFP07851.1 - 0.089 12.5 0.3 0.22 11.2 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KFP07852.1 - 3e-20 71.5 6.7 3.2e-20 71.4 4.7 1.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP07852.1 - 0.00047 19.1 0.1 0.00047 19.1 0.1 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFP07852.1 - 0.018 14.6 1.9 0.03 14.0 1.3 1.3 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.1 KFP07852.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox PF00046.24 KFP07854.1 - 4.1e-19 67.9 7.6 4.9e-19 67.7 5.2 1.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP07854.1 - 0.00017 21.2 2.2 0.00027 20.5 1.5 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KFP07854.1 - 0.0033 16.4 0.1 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez bZIP_1 PF00170.16 KFP07857.1 - 1.3e-12 47.4 8.0 2.4e-12 46.6 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFP07857.1 - 4.1e-10 39.3 7.8 8.5e-10 38.3 5.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFP07857.1 - 0.00012 22.3 7.0 0.00022 21.4 4.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Microtub_assoc PF07989.6 KFP07857.1 - 0.097 12.5 1.3 0.18 11.6 0.9 1.3 1 0 0 1 1 1 0 Microtubule associated dsrm PF00035.20 KFP07858.1 - 4.4e-21 75.2 0.0 1.1e-13 51.5 0.0 2.1 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFP07858.1 - 7.3e-09 35.7 0.3 0.00085 19.5 0.2 2.9 2 1 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 Pkinase PF00069.20 KFP07859.1 - 5e-52 176.6 0.0 5.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07859.1 - 4.4e-49 166.8 0.0 5.5e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP07859.1 - 0.045 13.4 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFP07859.1 - 0.058 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like KH_1 PF00013.24 KFP07860.1 - 1.6e-20 72.5 5.2 2.3e-14 52.7 0.3 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFP07860.1 - 1.5e-19 69.1 7.3 6.5e-13 48.0 2.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFP07860.1 - 0.011 15.3 2.3 0.017 14.6 0.6 1.9 2 0 0 2 2 2 0 KH domain PFK PF00365.15 KFP07861.1 - 8.4e-10 38.0 0.0 1.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Phosphofructokinase Lectin_leg-like PF03388.8 KFP07862.1 - 1.6e-78 262.9 0.0 2.2e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KFP07862.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Legume lectin domain AhpC-TSA_2 PF13911.1 KFP07862.1 - 0.0083 16.0 0.4 3.1 7.7 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA antioxidant enzyme HJURP_C PF12347.3 KFP07862.1 - 0.051 13.1 0.8 0.12 12.0 0.5 1.6 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat ApoLp-III PF07464.6 KFP07862.1 - 0.074 13.0 5.3 0.13 12.3 0.2 2.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4407 PF14362.1 KFP07862.1 - 0.37 9.6 4.0 0.52 9.2 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4404 PF14357.1 KFP07862.1 - 0.41 11.0 6.1 5 7.6 0.3 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) DUF3086 PF11285.3 KFP07862.1 - 1.1 7.9 7.6 0.21 10.3 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) OmpH PF03938.9 KFP07862.1 - 1.3 8.9 12.2 5.6 6.8 8.5 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_32 PF13654.1 KFP07862.1 - 1.4 7.4 10.5 13 4.2 7.3 2.0 1 1 0 1 1 1 0 AAA domain V-SNARE PF05008.10 KFP07862.1 - 1.7 8.8 6.9 0.19 11.8 0.7 2.5 3 0 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus DUF148 PF02520.12 KFP07862.1 - 2.7 7.8 7.6 2.8 7.7 3.1 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 Rootletin PF15035.1 KFP07862.1 - 6.2 6.7 9.7 9.5 6.1 0.3 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Kinetocho_Slk19 PF12709.2 KFP07862.1 - 7.4 6.7 10.1 2.8 8.0 0.1 3.1 3 0 0 3 3 3 0 Central kinetochore-associated Synaphin PF05835.7 KFP07863.1 - 2.2e-26 92.6 10.1 3e-26 92.2 7.0 1.2 1 0 0 1 1 1 1 Synaphin protein DUF4291 PF14124.1 KFP07863.1 - 0.1 12.1 1.6 0.13 11.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) DUF4449 PF14613.1 KFP07863.1 - 8.1 6.3 8.6 1.1 9.1 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) Peptidase_S24 PF00717.18 KFP07864.1 - 1.4e-11 43.8 0.1 2.1e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF504 PF04457.7 KFP07864.1 - 0.031 14.4 1.0 0.069 13.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF504) zf-C2H2 PF00096.21 KFP07865.1 - 4.6e-15 54.9 111.6 0.0061 16.8 0.3 15.0 15 0 0 15 15 15 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07865.1 - 1.9e-07 30.9 101.5 0.004 17.3 0.3 14.3 14 0 0 14 14 14 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP07865.1 - 1.3e-06 28.3 2.4 0.00039 20.4 0.1 10.0 12 0 0 12 12 12 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP07865.1 - 0.0018 18.4 3.4 0.024 14.8 0.2 11.0 12 0 0 12 12 12 4 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KFP07865.1 - 0.0092 16.2 83.9 0.23 11.8 0.4 14.4 15 2 1 16 16 16 6 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFP07865.1 - 0.044 13.7 0.1 0.044 13.7 0.1 11.7 13 0 0 13 13 13 0 C2H2-type zinc finger Peptidase_C14 PF00656.17 KFP07866.1 - 8.5e-20 71.4 0.0 1.8e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Caspase domain Trehalose_PPase PF02358.11 KFP07866.1 - 0.06 12.2 0.1 0.22 10.3 0.0 1.9 2 0 0 2 2 2 0 Trehalose-phosphatase Alpha_kinase PF02816.13 KFP07867.1 - 1.2e-43 148.9 0.0 1.8e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Tsg PF04668.7 KFP07867.1 - 0.0058 16.8 0.3 0.0085 16.2 0.2 1.4 1 0 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region DUF1227 PF06777.6 KFP07867.1 - 0.068 12.8 0.0 0.22 11.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1227) zf-CCHC_3 PF13917.1 KFP07867.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.6 3 0 0 3 3 3 0 Zinc knuckle HECT PF00632.20 KFP07868.1 - 1.4e-97 326.7 0.1 1.9e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFP07868.1 - 2e-47 158.5 29.5 4e-12 45.7 0.1 5.1 5 0 0 5 5 5 4 WW domain C2 PF00168.25 KFP07868.1 - 5e-18 64.7 0.1 1.2e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 C2 domain tRNA-synt_2 PF00152.15 KFP07869.1 - 2.3e-79 266.6 0.0 4.1e-79 265.7 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFP07869.1 - 1.6e-11 43.8 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.6 KFP07869.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Ferrochelatase PF00762.14 KFP07870.1 - 4.1e-106 354.5 0.0 4.7e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Homeobox PF00046.24 KFP07871.1 - 1.7e-11 43.5 1.2 2.8e-11 42.8 0.8 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP07871.1 - 3.2e-05 23.5 0.2 9.7e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Homeobox KN domain PH_3 PF14593.1 KFP07871.1 - 0.048 13.5 0.6 0.059 13.2 0.4 1.1 1 0 0 1 1 1 0 PH domain DUF2194 PF09960.4 KFP07871.1 - 0.065 11.2 0.1 0.063 11.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) WD40 PF00400.27 KFP07872.1 - 6.5e-26 89.2 25.9 7.7e-06 25.5 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KFP07872.1 - 0.19 9.8 3.2 1.3 7.0 0.8 3.0 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PITH PF06201.8 KFP07873.1 - 4.4e-46 156.4 0.0 6.5e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KFP07873.1 - 8.8e-16 57.4 0.0 1.4e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Sad1_UNC PF07738.8 KFP07873.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Ras PF00071.17 KFP07875.1 - 4.6e-55 185.4 0.0 5.9e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP07875.1 - 4.6e-16 59.3 0.0 6.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP07875.1 - 1.3e-13 50.5 0.0 2.1e-13 49.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP07875.1 - 0.00024 20.5 0.0 0.00043 19.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFP07875.1 - 0.0042 16.2 0.1 0.014 14.5 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFP07875.1 - 0.0079 16.3 0.0 0.026 14.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 KFP07875.1 - 0.011 15.3 0.6 0.21 11.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 KFP07875.1 - 0.11 11.8 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 KFP07875.1 - 0.17 11.2 0.3 1.4 8.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain cNMP_binding PF00027.24 KFP07877.1 - 2.5e-20 72.0 0.0 4.5e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 KFP07877.1 - 4.3e-17 62.0 10.0 1.1e-16 60.6 6.9 1.7 1 1 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.5 KFP07877.1 - 3.4e-12 45.4 1.2 3.4e-12 45.4 0.8 2.2 2 0 0 2 2 2 1 Ion transport protein N-terminal Ion_trans_2 PF07885.11 KFP07877.1 - 0.0086 15.7 0.6 0.0086 15.7 0.4 2.2 2 0 0 2 2 2 1 Ion channel DUF1759 PF03564.10 KFP07877.1 - 0.043 13.6 1.2 0.41 10.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) PDCD9 PF07147.7 KFP07878.1 - 1.7e-115 386.2 0.0 2e-115 385.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) FGF PF00167.13 KFP07879.1 - 3.3e-45 152.8 4.5 4.2e-45 152.4 3.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.8 KFP07879.1 - 0.00028 20.9 0.2 0.0008 19.4 0.1 1.8 1 1 1 2 2 2 2 Fascin domain SR-25 PF10500.4 KFP07879.1 - 0.011 15.1 1.5 0.011 15.1 1.0 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TraW_N PF12477.3 KFP07879.1 - 0.083 12.8 0.2 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal PNTB PF02233.11 KFP07880.1 - 3.8e-211 701.8 16.3 3.8e-211 701.8 11.3 2.3 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KFP07880.1 - 3.7e-53 179.5 1.2 6.8e-53 178.6 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KFP07880.1 - 3.9e-46 156.4 0.4 2.1e-45 154.0 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KFP07880.1 - 2.5e-32 110.8 3.1 2.5e-32 110.8 2.2 4.8 4 2 1 5 5 5 1 Domain of unknown function (DUF3814) ADH_zinc_N PF00107.21 KFP07880.1 - 0.002 17.7 2.1 0.008 15.7 0.2 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFP07880.1 - 0.0047 16.1 0.7 0.49 9.5 0.1 2.7 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 KFP07880.1 - 0.026 14.2 0.1 12 5.6 0.0 3.5 4 0 0 4 4 4 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox PF00070.22 KFP07880.1 - 0.073 13.4 0.5 0.18 12.2 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ComX PF05952.7 KFP07880.1 - 0.08 12.4 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 Bacillus competence pheromone ComX MIF4G PF02854.14 KFP07881.1 - 2.1e-27 95.9 0.0 2.8e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.10 KFP07881.1 - 0.0034 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DIT1_PvcA PF05141.7 KFP07881.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF457 PF04307.9 KFP07882.1 - 0.0055 16.0 13.5 0.011 15.0 9.4 1.5 1 1 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) HMG_CoA_synt_C PF08540.5 KFP07883.1 - 2.6e-128 427.3 0.4 3.3e-128 427.0 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFP07883.1 - 3.2e-107 355.6 0.4 4.4e-107 355.2 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 KFP07883.1 - 0.0003 20.3 0.1 0.00067 19.2 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.20 KFP07884.1 - 1.1e-69 234.4 0.0 1.5e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07884.1 - 1.3e-39 135.8 0.0 1.9e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP07884.1 - 6.8e-09 35.0 0.0 9.7e-09 34.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFP07884.1 - 0.00025 20.4 0.1 0.00038 19.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFP07884.1 - 0.002 17.2 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.26 KFP07885.1 - 9.7e-25 86.7 0.7 2.6e-24 85.3 0.3 2.0 2 0 0 2 2 2 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP07885.1 - 1.2e-15 56.8 54.9 9.9e-08 31.9 4.5 7.7 7 0 0 7 7 7 6 Zinc-finger double domain zf-C2H2 PF00096.21 KFP07885.1 - 2.3e-13 49.6 55.6 0.012 15.9 0.1 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP07885.1 - 2.4e-11 43.1 56.4 0.022 15.0 3.7 6.8 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.2 KFP07885.1 - 1.9e-06 27.8 5.5 0.00064 19.8 0.6 6.6 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP07885.1 - 1.8e-05 24.7 43.6 0.00095 19.2 0.3 6.8 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KFP07885.1 - 0.007 15.9 2.0 1.1 8.9 0.0 3.7 3 0 0 3 3 3 1 GAGA factor zf-C2H2_6 PF13912.1 KFP07885.1 - 0.055 13.3 43.2 0.28 11.1 0.1 6.7 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFP07885.1 - 2.6 8.2 38.0 2.9 8.0 1.2 6.7 2 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFP07885.1 - 9.7 5.9 21.3 0.38 10.4 0.6 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type SelP_N PF04592.9 KFP07886.1 - 6.4e-37 127.2 8.7 7e-37 127.0 6.0 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Zip PF02535.17 KFP07886.1 - 1.2 8.0 5.4 1.2 8.1 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Microvir_H PF04687.7 KFP07887.1 - 0.031 13.3 2.8 0.057 12.4 2.0 1.4 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Tropomyosin_1 PF12718.2 KFP07887.1 - 0.23 11.3 28.5 0.51 10.1 4.9 2.2 1 1 1 2 2 2 0 Tropomyosin like DUF885 PF05960.6 KFP07887.1 - 0.29 10.2 8.3 0.32 10.0 5.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) CALCOCO1 PF07888.6 KFP07887.1 - 0.53 8.5 24.3 0.25 9.5 5.4 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.4 KFP07887.1 - 4.7 7.0 29.8 0.2 11.5 13.6 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cupin_8 PF13621.1 KFP07887.1 - 9 5.7 7.1 17 4.8 4.8 1.6 1 1 0 1 1 1 0 Cupin-like domain GHBP PF12772.2 KFP07888.1 - 2.1e-104 349.1 5.0 2.8e-104 348.6 3.4 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding EpoR_lig-bind PF09067.5 KFP07888.1 - 5.4e-13 48.8 3.1 5.4e-13 48.8 2.2 2.4 3 0 0 3 3 3 1 Erythropoietin receptor, ligand binding fn3 PF00041.16 KFP07888.1 - 4.7e-07 29.8 0.2 1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain IL6Ra-bind PF09240.5 KFP07888.1 - 0.018 15.2 1.4 0.061 13.5 1.0 1.9 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding I-set PF07679.11 KFP07889.1 - 1.1e-43 147.0 0.0 8.5e-14 51.1 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ADAM_spacer1 PF05986.9 KFP07889.1 - 2.2e-35 120.9 0.0 3.6e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 ADAM-TS Spacer 1 Ig_2 PF13895.1 KFP07889.1 - 1.8e-34 117.6 0.2 1.5e-11 44.2 0.1 3.9 3 0 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.1 KFP07889.1 - 1.3e-27 96.1 8.9 2e-09 37.8 0.5 4.4 5 0 0 5 5 3 3 Immunoglobulin domain V-set PF07686.12 KFP07889.1 - 7.6e-27 93.4 1.3 1.7e-09 37.6 0.1 4.7 3 3 0 3 3 3 3 Immunoglobulin V-set domain ig PF00047.20 KFP07889.1 - 1.2e-24 86.2 0.1 1e-06 28.7 0.0 3.9 3 0 0 3 3 3 3 Immunoglobulin domain TSP_1 PF00090.14 KFP07889.1 - 1.2e-24 86.1 68.5 1.1e-08 35.0 8.2 5.9 5 0 0 5 5 4 4 Thrombospondin type 1 domain Kunitz_BPTI PF00014.18 KFP07889.1 - 2.1e-17 63.0 5.6 2.1e-17 63.0 3.9 4.8 5 1 0 5 5 3 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PLAC PF08686.6 KFP07889.1 - 3.3e-12 46.4 6.5 1.6e-11 44.2 4.5 2.4 1 0 0 1 1 1 1 PLAC (protease and lacunin) domain V-set_CD47 PF08204.6 KFP07889.1 - 0.0033 17.1 0.0 0.06 13.1 0.4 2.6 3 1 0 3 3 3 1 CD47 immunoglobulin-like domain C2-set PF05790.10 KFP07889.1 - 0.0091 15.9 0.0 2.1 8.3 0.0 3.8 4 0 0 4 4 4 1 Immunoglobulin C2-set domain Presenilin PF01080.12 KFP07890.1 - 2.5e-172 573.2 21.9 4.2e-170 565.9 15.2 2.0 1 1 0 1 1 1 1 Presenilin CHD5 PF04420.9 KFP07890.1 - 6.6 6.3 7.1 1 8.9 1.8 1.9 2 0 0 2 2 2 0 CHD5-like protein PWI PF01480.12 KFP07891.1 - 5.8e-18 64.7 0.4 1.8e-17 63.2 0.3 1.9 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 KFP07891.1 - 4.9e-09 35.6 0.0 9.2e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07891.1 - 0.0069 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 KFP07892.1 - 1.5e-30 104.9 25.2 7.7e-17 60.9 7.6 5.6 5 1 0 5 5 5 2 FYVE zinc finger GBP PF02263.14 KFP07892.1 - 0.00045 19.3 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AIG1 PF04548.11 KFP07892.1 - 0.0046 16.0 0.0 0.0091 15.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family WD40 PF00400.27 KFP07893.1 - 0.016 15.0 1.5 1.2 9.1 0.0 3.8 3 1 0 3 3 3 0 WD domain, G-beta repeat Nup160 PF11715.3 KFP07893.1 - 0.085 10.9 0.0 0.52 8.3 0.0 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Requiem_N PF14051.1 KFP07894.1 - 1.4e-37 127.4 0.2 2.5e-37 126.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PHD PF00628.24 KFP07894.1 - 2.8e-21 74.9 23.8 3.9e-12 45.6 3.6 3.4 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 KFP07894.1 - 0.006 15.8 1.5 0.006 15.8 1.0 3.9 3 1 1 4 4 4 2 PHD-finger zf-PHD-like PF15446.1 KFP07894.1 - 0.0096 15.2 2.6 0.0096 15.2 1.8 3.0 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain zf-C2H2_4 PF13894.1 KFP07894.1 - 0.01 16.0 0.8 0.01 16.0 0.5 4.3 4 1 0 4 4 4 0 C2H2-type zinc finger C1_1 PF00130.17 KFP07894.1 - 0.033 13.9 19.0 0.89 9.3 0.3 4.3 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2 PF00096.21 KFP07894.1 - 0.036 14.4 1.2 0.036 14.4 0.9 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP07894.1 - 0.057 13.7 0.4 0.057 13.7 0.3 5.4 7 1 0 7 7 7 0 Zinc-finger double domain Prok-RING_1 PF14446.1 KFP07894.1 - 0.23 11.2 21.7 0.34 10.6 4.4 4.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 RGS PF00615.14 KFP07895.1 - 1.6e-33 115.2 0.4 1.6e-33 115.2 0.3 2.3 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 KFP07895.1 - 1.3e-15 56.8 0.0 3.4e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.17 KFP07895.1 - 2.1e-13 49.7 0.0 5e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 GGL domain DUF1203 PF06718.6 KFP07895.1 - 0.017 14.9 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) AAA PF00004.24 KFP07897.1 - 1.4e-12 47.9 0.0 2.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP07897.1 - 6.9e-05 22.9 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFP07897.1 - 0.00012 22.9 0.0 0.00019 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFP07897.1 - 0.00016 21.6 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFP07897.1 - 0.00036 19.6 0.0 0.00052 19.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFP07897.1 - 0.00041 20.3 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KFP07897.1 - 0.00041 20.0 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFP07897.1 - 0.0006 19.5 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFP07897.1 - 0.00088 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KFP07897.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFP07897.1 - 0.0035 16.5 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KFP07897.1 - 0.0054 15.4 0.0 0.007 15.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 KFP07897.1 - 0.0065 15.8 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFP07897.1 - 0.0066 16.0 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFP07897.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 KFP07897.1 - 0.019 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFP07897.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.11 KFP07897.1 - 0.022 13.9 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KFP07897.1 - 0.04 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain SKI PF01202.17 KFP07897.1 - 0.061 13.1 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Shikimate kinase KaiC PF06745.8 KFP07897.1 - 0.065 12.3 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.1 KFP07897.1 - 0.072 12.6 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KFP07897.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KFP07897.1 - 0.17 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PDZ PF00595.19 KFP07898.1 - 3.7e-21 75.0 0.1 5.8e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP07898.1 - 2.3e-08 33.7 0.1 2.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 KFP07898.1 - 0.0058 16.3 0.1 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_C97 PF05903.9 KFP07899.1 - 4.8e-41 140.0 0.0 5.8e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF3670 PF12419.3 KFP07899.1 - 0.11 11.9 0.1 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 SNF2 Helicase protein LRAT PF04970.8 KFP07899.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Calx-beta PF03160.9 KFP07901.1 - 1.7e-62 207.5 8.5 9.4e-31 105.7 0.1 2.8 3 0 0 3 3 3 2 Calx-beta domain Na_Ca_ex PF01699.19 KFP07901.1 - 3e-60 201.8 27.3 1.2e-34 118.9 5.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1735 PF08522.5 KFP07901.1 - 0.068 13.5 1.6 1.8 9.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1735) Phage_XkdX PF09693.5 KFP07901.1 - 0.31 10.5 3.5 0.68 9.4 2.4 1.6 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Acyl_transf_3 PF01757.17 KFP07901.1 - 0.42 9.3 26.6 0.12 11.2 8.6 2.5 2 0 0 2 2 2 0 Acyltransferase family Thyroglobulin_1 PF00086.13 KFP07902.1 - 8.7e-28 95.4 24.9 6.8e-16 57.3 3.4 3.3 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.4 KFP07902.1 - 8.7e-14 51.5 0.0 1.8e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Kazal_2 PF07648.10 KFP07902.1 - 1.1e-05 25.2 3.6 1.1e-05 25.2 2.5 3.5 4 0 0 4 4 4 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KFP07902.1 - 0.0004 20.3 11.0 0.00041 20.2 4.1 3.4 3 0 0 3 3 3 1 Kazal-type serine protease inhibitor domain EF-hand_7 PF13499.1 KFP07902.1 - 0.002 18.2 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFP07902.1 - 0.01 15.6 0.1 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 KFP07902.1 - 0.02 14.1 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 EF hand DUF1977 PF09320.6 KFP07902.1 - 0.085 13.1 0.2 0.085 13.1 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1977) EF-hand_5 PF13202.1 KFP07902.1 - 0.14 11.5 0.0 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 EF hand RRM_1 PF00076.17 KFP07903.1 - 6.1e-31 105.8 0.1 1.7e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07903.1 - 5.9e-22 77.4 0.0 8.3e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07903.1 - 4.6e-11 42.3 0.0 3.1e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP07903.1 - 1e-06 28.4 0.1 0.0083 15.9 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KFP07903.1 - 0.00024 20.7 0.0 0.00088 19.0 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 KFP07903.1 - 0.059 13.0 0.0 6.3 6.5 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain DUF605 PF04652.11 KFP07903.1 - 0.33 10.3 4.8 0.43 9.9 3.3 1.1 1 0 0 1 1 1 0 Vta1 like CytochromB561_N PF09786.4 KFP07903.1 - 4.9 5.4 13.7 5.7 5.2 9.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 KFP07903.1 - 5.5 5.1 13.2 6 5.0 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Sushi PF00084.15 KFP07904.1 - 3.5e-09 36.8 6.5 5.9e-09 36.1 4.5 1.4 1 0 0 1 1 1 1 Sushi domain (SCR repeat) RSN1_TM PF13967.1 KFP07904.1 - 0.25 10.8 0.0 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport DUF4659 PF15558.1 KFP07905.1 - 1.7e-107 359.3 106.5 2.6e-98 329.1 67.5 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4659) KAT11 PF08214.6 KFP07907.1 - 2.8e-79 266.7 0.8 4.9e-79 265.9 0.6 1.3 1 0 0 1 1 1 1 Histone acetylation protein Creb_binding PF09030.5 KFP07907.1 - 2.5e-31 107.9 13.9 2.5e-31 107.9 9.6 7.7 3 2 6 9 9 9 1 Creb binding DUF902 PF06001.8 KFP07907.1 - 1.7e-24 85.6 8.1 1.7e-24 85.6 5.6 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) Bromodomain PF00439.20 KFP07907.1 - 9.4e-19 67.1 0.0 2.7e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.11 KFP07907.1 - 1.3e-16 60.3 25.1 1.3e-16 60.3 17.4 2.6 2 0 0 2 2 2 1 TAZ zinc finger ZZ PF00569.12 KFP07907.1 - 1.2e-14 53.5 14.2 1.2e-14 53.5 9.8 3.8 5 0 0 5 5 5 1 Zinc finger, ZZ type Paralemmin PF03285.10 KFP07907.1 - 0.00024 20.6 2.2 0.00024 20.6 1.5 1.8 2 0 0 2 2 2 1 Paralemmin Npa1 PF11707.3 KFP07907.1 - 0.00096 18.2 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal HSP90 PF00183.13 KFP07907.1 - 2 6.7 14.5 1 7.6 8.1 1.7 2 0 0 2 2 2 0 Hsp90 protein HSP90 PF00183.13 KFP07908.1 - 5.7e-80 269.2 5.6 4.7e-76 256.3 1.6 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 KFP07908.1 - 2.7e-13 49.7 0.1 1.8e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFP07908.1 - 2.6e-08 33.5 0.1 5.2e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BTB PF00651.26 KFP07909.1 - 3.1e-11 43.2 0.0 5.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Slx4 PF09494.5 KFP07910.1 - 1.7e-17 62.9 0.0 2.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease Ish1 PF10281.4 KFP07910.1 - 0.14 12.2 0.0 1.6 8.8 0.0 2.5 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Heme_oxygenase PF01126.15 KFP07911.1 - 1.1e-82 276.5 5.6 1.4e-82 276.2 3.9 1.1 1 0 0 1 1 1 1 Heme oxygenase zf-LITAF-like PF10601.4 KFP07912.1 - 2.2e-22 78.6 15.2 3.2e-22 78.1 10.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-C3HC4_3 PF13920.1 KFP07915.1 - 1.2e-14 53.6 8.9 1.9e-14 53.0 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP07915.1 - 1.2e-07 31.6 12.1 2e-07 30.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP07915.1 - 1.4e-05 24.8 11.9 2.4e-05 24.0 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFP07915.1 - 0.00043 19.9 9.9 0.00073 19.2 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KFP07915.1 - 0.014 14.9 6.1 0.028 13.9 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFP07915.1 - 0.97 9.0 8.0 1.7 8.3 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KFP07915.1 - 5.6 6.5 12.7 15 5.1 8.8 1.7 1 1 0 1 1 1 0 P-11 zinc finger DUF4507 PF14964.1 KFP07916.1 - 2.2e-127 424.7 0.2 2.6e-127 424.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) Exo_endo_phos PF03372.18 KFP07917.1 - 2.3e-09 37.5 0.0 2.6e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NanE PF04131.9 KFP07917.1 - 0.02 13.8 0.0 0.069 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Exo_endo_phos PF03372.18 KFP07918.1 - 1.2e-10 41.7 0.1 1.4e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFP07918.1 - 0.099 12.2 0.0 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase ECH PF00378.15 KFP07919.1 - 1.9e-73 246.6 0.0 2.1e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFP07919.1 - 0.052 13.3 0.6 6.5 6.5 0.0 3.0 4 0 0 4 4 4 0 Peptidase family S49 Voltage_CLC PF00654.15 KFP07920.1 - 6.9e-94 314.7 29.6 1.1e-93 314.0 17.7 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 KFP07920.1 - 2.2e-17 62.5 0.1 5.1e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain LUC7 PF03194.10 KFP07921.1 - 2.4e-83 279.5 18.2 2.4e-83 279.5 12.6 2.3 2 1 1 3 3 3 1 LUC7 N_terminus Spore_III_AB PF09548.5 KFP07921.1 - 3.7 7.2 7.2 1.3 8.8 2.6 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PQQ_2 PF13360.1 KFP07922.1 - 4.8e-06 26.2 0.6 0.014 14.8 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 KFP07922.1 - 0.00028 20.2 0.0 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat FG-GAP PF01839.18 KFP07922.1 - 0.0013 18.3 0.3 0.058 13.1 0.1 2.5 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.1 KFP07922.1 - 0.023 15.0 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_3 PF13570.1 KFP07922.1 - 0.18 12.1 0.5 22 5.4 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain RGS PF00615.14 KFP07923.1 - 2.1e-32 111.6 0.1 3.5e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain G-gamma PF00631.17 KFP07923.1 - 1.7e-09 37.3 0.2 8.5e-08 31.8 0.1 2.4 2 0 0 2 2 2 1 GGL domain DEP PF00610.16 KFP07923.1 - 2e-07 30.6 0.0 1.2e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Rho_GDI PF02115.12 KFP07924.1 - 6.8e-78 260.6 0.0 7.5e-78 260.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Thioredoxin PF00085.15 KFP07925.1 - 3.8e-51 171.1 0.0 2.2e-26 91.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KFP07925.1 - 1.1e-43 149.2 0.0 1.2e-36 126.2 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFP07925.1 - 1.3e-14 53.9 0.4 4.8e-06 26.5 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFP07925.1 - 4e-10 39.8 0.2 0.0002 21.5 0.0 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFP07925.1 - 6e-10 39.1 0.1 0.0022 18.0 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 KFP07925.1 - 7.6e-07 28.8 0.2 0.031 13.9 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KFP07925.1 - 0.0005 19.6 0.3 0.22 11.0 0.0 2.8 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.1 KFP07925.1 - 0.0011 18.7 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.1 KFP07925.1 - 0.0022 17.4 0.0 0.18 11.3 0.0 2.6 3 0 0 3 3 3 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 KFP07925.1 - 0.0033 17.3 0.0 0.32 11.0 0.0 3.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.1 KFP07925.1 - 0.0064 16.0 0.1 0.076 12.5 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_4 PF13462.1 KFP07925.1 - 0.12 12.3 0.9 5.4 6.9 0.0 3.0 2 1 0 3 3 3 0 Thioredoxin Arylsulfotrans PF05935.6 KFP07925.1 - 0.19 10.1 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) DIX PF00778.12 KFP07926.1 - 2e-31 107.5 0.8 3.6e-31 106.7 0.6 1.4 1 0 0 1 1 1 1 DIX domain RGS PF00615.14 KFP07926.1 - 2e-27 95.6 0.4 4.2e-27 94.6 0.3 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Axin_b-cat_bind PF08833.5 KFP07926.1 - 1.1e-18 66.6 2.7 3.3e-18 65.0 1.9 1.9 1 0 0 1 1 1 1 Axin beta-catenin binding domain Ribosomal_L28 PF00830.14 KFP07927.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L28 family DUF3522 PF12036.3 KFP07928.1 - 3.6e-64 215.9 18.2 3.6e-64 215.9 12.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) Globin PF00042.17 KFP07929.1 - 3.2e-30 104.7 0.0 4.2e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Globin Globin PF00042.17 KFP07930.1 - 9.3e-28 96.7 0.0 2.7e-27 95.2 0.0 1.7 2 0 0 2 2 2 1 Globin DUF111 PF01969.12 KFP07930.1 - 0.1 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 Globin PF00042.17 KFP07932.1 - 5.2e-29 100.7 0.0 7.1e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Globin NPR3 PF03666.8 KFP07933.1 - 2.1e-83 280.3 15.0 1.6e-70 237.9 7.3 4.0 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 KFP07933.1 - 0.00046 18.9 0.1 0.56 8.8 0.0 2.3 2 1 0 2 2 2 2 Nitrogen permease regulator 2 Pur_DNA_glyco PF02245.11 KFP07934.1 - 1.9e-58 196.6 0.0 2.2e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Rhomboid_SP PF12595.3 KFP07935.1 - 2.2e-106 354.1 1.5 3.6e-106 353.4 1.0 1.4 1 0 0 1 1 1 1 Rhomboid serine protease Rhomboid PF01694.17 KFP07935.1 - 5.5e-30 104.3 10.2 5.5e-30 104.3 7.1 1.7 2 0 0 2 2 2 1 Rhomboid family DUF4457 PF14652.1 KFP07936.1 - 8.7e-196 649.4 0.0 2.6e-134 447.3 0.0 4.9 3 2 1 4 4 4 4 Domain of unknown function (DUF4457) Sad1_UNC PF07738.8 KFP07936.1 - 2.2e-07 30.7 0.0 2 8.2 0.0 5.0 5 0 0 5 5 5 3 Sad1 / UNC-like C-terminal Phage-A118_gp45 PF10653.4 KFP07936.1 - 0.0083 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein gp45 of Bacteriophage A118 GSG-1 PF07803.6 KFP07937.1 - 2.6e-52 175.3 0.4 4.3e-52 174.6 0.3 1.4 1 0 0 1 1 1 1 GSG1-like protein Claudin_2 PF13903.1 KFP07937.1 - 5.7e-12 45.6 0.1 1e-11 44.8 0.1 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KFP07937.1 - 4e-07 29.8 13.5 4.7e-07 29.6 3.2 2.4 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family CD20 PF04103.10 KFP07937.1 - 2.1 8.2 13.8 2.2 8.1 4.6 3.3 3 1 0 3 3 3 0 CD20-like family Tissue_fac PF01108.12 KFP07938.1 - 2e-20 72.5 0.3 6.8e-20 70.7 0.1 2.0 2 0 0 2 2 2 1 Tissue factor Interfer-bind PF09294.5 KFP07938.1 - 4.8e-12 45.8 0.8 2.1e-11 43.8 0.5 1.9 1 1 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III fn3 PF00041.16 KFP07938.1 - 5.7e-05 23.1 0.2 0.48 10.5 0.0 2.5 2 1 0 2 2 2 2 Fibronectin type III domain Fox-1_C PF12414.3 KFP07940.1 - 2.6e-41 139.9 22.0 2.6e-41 139.9 15.2 2.8 3 0 0 3 3 3 1 Calcitonin gene-related peptide regulator C terminal RRM_1 PF00076.17 KFP07940.1 - 9.1e-19 66.8 0.1 1.7e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07940.1 - 2.4e-15 56.2 0.1 4.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07940.1 - 4.4e-11 42.4 0.2 1.8e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP07940.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif UBN_AB PF14075.1 KFP07941.1 - 6.3e-80 267.8 1.0 6.3e-80 267.8 0.7 2.7 2 1 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.5 KFP07941.1 - 4.5e-20 71.2 0.5 4.5e-20 71.2 0.4 3.6 3 0 0 3 3 3 1 HPC2 and ubinuclein domain Cellulose_synt PF03552.9 KFP07941.1 - 3.5 5.7 3.6 5.7 5.1 2.5 1.2 1 0 0 1 1 1 0 Cellulose synthase PDZ PF00595.19 KFP07942.1 - 6.1e-11 42.3 0.1 1.8e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF812 PF05667.6 KFP07942.1 - 0.005 15.4 7.6 0.007 14.9 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 KFP07942.1 - 0.14 10.0 6.1 0.19 9.5 4.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC74_C PF14917.1 KFP07942.1 - 0.24 11.4 5.5 0.68 9.9 3.8 1.9 1 1 0 1 1 1 0 Coiled coil protein 74, C terminal Laminin_II PF06009.7 KFP07942.1 - 0.41 10.4 9.9 0.77 9.5 6.9 1.5 1 0 0 1 1 1 0 Laminin Domain II Med9 PF07544.8 KFP07942.1 - 0.48 10.2 6.9 0.13 12.0 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 KFP07942.1 - 0.74 9.5 20.9 0.25 11.1 7.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KFP07942.1 - 0.77 8.7 13.0 1.2 8.1 9.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 KFP07942.1 - 2.6 8.0 19.7 11 5.9 13.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 KFP07942.1 - 2.6 8.0 13.6 1.3 9.0 7.8 1.8 2 0 0 2 2 2 0 DivIVA protein DUF1192 PF06698.6 KFP07942.1 - 3.2 7.6 5.8 12 5.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CobN-Mg_chel PF02514.11 KFP07942.1 - 4.1 4.6 7.6 5.9 4.1 5.2 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase TBPIP PF07106.8 KFP07942.1 - 6 6.3 17.9 0.88 9.1 6.8 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 KFP07942.1 - 8.2 6.8 12.2 0.85 10.0 1.6 3.2 2 1 1 3 3 3 0 SlyX PRELI PF04707.9 KFP07943.1 - 1.9e-45 154.2 0.1 5.7e-45 152.7 0.4 1.5 2 0 0 2 2 2 1 PRELI-like family CRAL_TRIO PF00650.15 KFP07943.1 - 8.3e-43 145.6 0.0 1.7e-42 144.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFP07943.1 - 4.9e-10 39.3 0.2 1.2e-09 38.0 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFP07943.1 - 0.016 15.0 0.0 0.058 13.3 0.0 1.9 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2233 PF09992.4 KFP07944.1 - 1.5e-36 125.9 0.1 2e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2233) hEGF PF12661.2 KFP07944.1 - 0.0013 18.6 18.5 0.035 14.2 1.8 4.4 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.8 KFP07944.1 - 0.0045 17.1 10.2 0.0045 17.1 7.1 4.8 3 1 1 4 4 4 3 EGF-like domain Glyco_trans_1_4 PF13692.1 KFP07945.1 - 3.1e-15 56.5 0.0 7.6e-15 55.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KFP07945.1 - 6.1e-07 29.0 0.0 8.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFP07945.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KFP07945.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_16 PF10294.4 KFP07946.1 - 5.1e-19 68.3 0.0 8.1e-09 35.1 0.0 2.1 1 1 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KFP07946.1 - 0.0026 18.3 0.0 0.004 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP07946.1 - 0.046 13.1 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KFP07946.1 - 0.085 13.3 0.0 0.19 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_C2 PF00648.16 KFP07947.1 - 8e-85 284.4 0.0 1.2e-84 283.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease zf-RanBP PF00641.13 KFP07947.1 - 4.5e-23 80.0 48.7 2.1e-07 29.9 1.4 6.0 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others DZR PF12773.2 KFP07947.1 - 3.7e-05 23.4 49.9 0.0028 17.4 5.6 5.5 3 1 1 5 5 5 4 Double zinc ribbon zf-C2H2_7 PF15269.1 KFP07949.1 - 1.4e-38 130.5 11.7 3.6e-38 129.2 8.1 1.7 1 0 0 1 1 1 1 Zinc-finger NHL PF01436.16 KFP07949.1 - 9.4e-20 69.4 4.3 0.00027 20.7 0.0 5.3 5 0 0 5 5 5 4 NHL repeat SGL PF08450.7 KFP07949.1 - 8.5e-05 22.0 0.1 0.22 10.8 0.0 2.7 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Gpi1 PF05024.10 KFP07950.1 - 2.2e-52 177.4 3.7 7.4e-52 175.7 2.5 2.0 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.17 KFP07951.1 - 8.3e-34 116.3 0.0 1.1e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SOCS_box PF07525.11 KFP07951.1 - 9.4e-11 41.3 0.4 2e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 SOCS box Miro PF08477.8 KFP07951.1 - 2.7e-09 37.5 0.0 4.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP07951.1 - 0.0079 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Kunitz_BPTI PF00014.18 KFP07952.1 - 4e-36 123.0 18.9 1.2e-19 70.2 3.6 2.4 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain NTR PF01759.16 KFP07952.1 - 1.3e-09 37.5 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Tcell_CD4_Cterm PF12104.3 KFP07952.1 - 0.0055 16.2 0.3 0.016 14.7 0.2 1.9 1 0 0 1 1 1 1 T cell CD4 receptor C terminal region DUF938 PF06080.7 KFP07953.1 - 9e-28 97.2 0.0 9.9e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.7 KFP07953.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain FAM195 PF14799.1 KFP07954.1 - 1e-31 108.7 0.6 1.1e-31 108.6 0.4 1.0 1 0 0 1 1 1 1 FAM195 family LAP2alpha PF11560.3 KFP07954.1 - 0.024 13.7 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha DUF3438 PF11920.3 KFP07954.1 - 0.13 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) ABC2_membrane_3 PF12698.2 KFP07955.1 - 2e-61 207.9 37.4 2e-34 119.1 17.2 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 KFP07955.1 - 2.7e-48 163.7 0.0 4.3e-23 82.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KFP07955.1 - 9.6e-17 61.8 0.0 5.8e-05 23.1 0.0 4.3 3 1 0 4 4 4 3 AAA domain AAA_23 PF13476.1 KFP07955.1 - 4e-05 24.0 1.4 0.0056 17.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 KFP07955.1 - 0.00087 19.1 0.0 0.063 13.2 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KFP07955.1 - 0.001 18.3 1.3 0.012 14.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFP07955.1 - 0.0016 17.5 0.0 0.42 9.5 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 KFP07955.1 - 0.002 17.6 3.0 0.055 13.0 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.1 KFP07955.1 - 0.05 13.1 0.8 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 KFP07955.1 - 0.052 12.7 0.5 10 5.3 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.1 KFP07955.1 - 0.067 13.3 0.3 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KFP07955.1 - 0.11 11.9 4.9 0.88 8.9 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 KFP07955.1 - 0.14 10.6 0.2 1.4 7.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KFP07955.1 - 0.17 11.5 1.7 2.8 7.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KFP07955.1 - 0.18 11.6 0.2 15 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KFP07955.1 - 0.56 9.3 0.3 10 5.2 0.0 2.9 3 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 KFP07955.1 - 1.5 8.2 3.9 11 5.4 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RELT PF12606.3 KFP07955.1 - 5.5 6.2 5.8 16 4.6 4.0 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Pkinase PF00069.20 KFP07956.1 - 1.5e-13 50.5 0.0 1.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP07956.1 - 2.2e-06 26.9 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase fn3 PF00041.16 KFP07958.1 - 2.1e-10 40.5 0.1 4.1e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Ank_2 PF12796.2 KFP07958.1 - 0.00029 21.0 0.0 0.00063 20.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP07958.1 - 0.00076 19.9 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP07958.1 - 0.0034 17.5 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KFP07958.1 - 0.0097 15.6 0.1 0.06 13.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Tmemb_cc2 PF10267.4 KFP07959.1 - 0.0012 17.5 1.3 0.0012 17.5 0.9 1.5 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Retrotrans_gag PF03732.12 KFP07959.1 - 0.011 15.8 1.6 0.02 14.9 0.9 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein DUF1221 PF06760.6 KFP07959.1 - 0.072 12.3 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Laminin_N PF00055.12 KFP07961.1 - 3.4e-50 170.2 1.9 9.8e-49 165.4 0.0 2.8 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) NTR PF01759.16 KFP07961.1 - 1.1e-28 99.0 1.9 3.2e-28 97.5 1.3 1.9 1 0 0 1 1 1 1 UNC-6/NTR/C345C module Laminin_EGF PF00053.19 KFP07961.1 - 1.6e-20 72.7 57.9 1.6e-11 43.9 8.3 5.0 4 1 1 5 5 5 3 Laminin EGF-like (Domains III and V) TLD PF07534.11 KFP07962.1 - 1.9e-25 89.4 0.1 2.2e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 TLD RabGAP-TBC PF00566.13 KFP07962.1 - 1e-22 80.6 0.3 1.7e-22 79.9 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ATP-synt_C PF00137.16 KFP07963.1 - 3e-31 107.1 28.3 5.1e-19 67.9 8.2 2.0 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 KFP07963.1 - 0.026 13.6 0.2 0.064 12.3 0.0 1.6 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor Amidohydro_1 PF01979.15 KFP07964.1 - 3.6e-12 46.5 0.9 9.9e-12 45.1 0.6 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFP07964.1 - 2.1e-09 37.8 0.8 5.2e-08 33.2 0.5 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFP07964.1 - 0.00014 21.6 0.0 0.00034 20.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFP07964.1 - 0.0021 17.3 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family DUF4615 PF15393.1 KFP07965.1 - 1.3e-39 135.1 2.4 1.3e-39 135.1 1.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4615) RRM_1 PF00076.17 KFP07966.1 - 2.5e-20 71.8 0.0 3.7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07966.1 - 9.2e-16 57.5 0.0 1.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07966.1 - 2.5e-10 40.0 0.0 3.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFP07966.1 - 0.00057 19.5 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 KFP07966.1 - 0.00058 19.6 0.0 0.0019 17.9 0.0 1.9 1 1 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFP07966.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF605 PF04652.11 KFP07966.1 - 0.024 14.0 22.4 0.027 13.8 15.5 1.1 1 0 0 1 1 1 0 Vta1 like SOBP PF15279.1 KFP07966.1 - 0.054 13.8 17.8 0.072 13.4 12.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 KFP07966.1 - 0.11 10.7 30.4 0.13 10.5 21.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 KFP07966.1 - 4.9 5.3 20.9 5.6 5.1 14.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF936 PF06075.7 KFP07966.1 - 5.5 5.7 39.6 6.3 5.5 27.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Telomere_reg-2 PF10193.4 KFP07967.1 - 1.1e-36 125.6 0.1 2.4e-36 124.4 0.1 1.7 1 0 0 1 1 1 1 Telomere length regulation protein L_HGMIC_fpl PF10242.4 KFP07968.1 - 0.00021 21.3 7.3 0.00054 20.0 3.4 2.5 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.7 KFP07968.1 - 0.00032 20.0 0.1 0.00032 20.0 0.1 2.2 3 1 0 3 3 3 1 Clc-like Claudin_3 PF06653.6 KFP07968.1 - 0.00091 18.9 4.6 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Tight junction protein, Claudin-like Claudin_2 PF13903.1 KFP07968.1 - 0.058 13.0 7.8 0.82 9.3 5.4 2.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Neurensin PF14927.1 KFP07968.1 - 0.06 12.7 0.3 0.16 11.3 0.1 1.9 1 1 0 1 1 1 0 Neurensin Myb_DNA-binding PF00249.26 KFP07969.1 - 0.019 14.9 0.0 0.11 12.6 0.0 2.3 1 1 0 1 1 1 0 Myb-like DNA-binding domain TSC21 PF15217.1 KFP07969.1 - 0.031 13.9 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 TSC21 family NAD_binding_2 PF03446.10 KFP07972.1 - 6.9e-41 139.8 0.0 1.3e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFP07972.1 - 5.1e-23 81.4 1.3 9.8e-23 80.5 0.9 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.12 KFP07972.1 - 5.7e-17 61.7 0.9 1.3e-16 60.5 0.6 1.6 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.12 KFP07972.1 - 6.2e-08 32.9 0.0 1.7e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KFP07972.1 - 2.5e-05 23.4 0.0 0.00018 20.7 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFP07972.1 - 0.00022 21.3 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KFP07972.1 - 0.00053 19.4 0.0 0.00097 18.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFP07972.1 - 0.0024 17.5 0.0 0.0061 16.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFP07972.1 - 0.04 13.6 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AT_hook PF02178.14 KFP07972.1 - 3.8 7.4 11.9 0.091 12.4 2.8 2.6 2 0 0 2 2 2 0 AT hook motif FRG2 PF15315.1 KFP07972.1 - 5.1 7.0 15.0 10 6.0 10.4 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Rogdi_lz PF10259.4 KFP07973.1 - 5.5e-63 212.6 1.1 7.7e-63 212.1 0.8 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein FlaC_arch PF05377.6 KFP07974.1 - 0.0095 15.8 1.9 0.0095 15.8 1.3 3.9 3 1 1 4 4 4 1 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KFP07974.1 - 7.7 6.3 20.1 2.9 7.7 3.3 3.3 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ras PF00071.17 KFP07976.1 - 2.4e-50 170.0 0.0 2.7e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP07976.1 - 4.8e-13 49.6 0.0 6.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP07976.1 - 2.2e-05 23.7 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP07976.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Lipase_3 PF01764.20 KFP07977.1 - 1.8e-15 56.7 0.0 2.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KFP07977.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP07977.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ER_lumen_recept PF00810.13 KFP07978.1 - 3e-58 196.4 9.1 4.6e-58 195.8 6.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KFP07978.1 - 0.035 13.6 1.4 0.035 13.6 1.0 2.6 2 2 1 3 3 3 0 PQ loop repeat DUF3240 PF11582.3 KFP07979.1 - 0.1 12.5 0.8 0.81 9.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3240) DREV PF05219.7 KFP07980.1 - 2.2e-135 449.6 0.0 2.5e-135 449.4 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.1 KFP07980.1 - 7.4e-12 45.2 0.0 1.4e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP07980.1 - 1e-08 35.5 0.0 1.6e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP07980.1 - 3.4e-06 27.4 0.0 5.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP07980.1 - 8.5e-06 25.4 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP07980.1 - 6.5e-05 23.4 0.0 0.00031 21.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KFP07980.1 - 0.0033 16.5 0.0 0.0071 15.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 KFP07980.1 - 0.06 12.7 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_PK PF05891.7 KFP07980.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase V-set PF07686.12 KFP07981.1 - 4.6e-08 32.9 0.2 8.6e-08 32.0 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.11 KFP07981.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain MFS_2 PF13347.1 KFP07982.1 - 1.1e-36 126.1 25.4 1.5e-36 125.7 17.6 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Myosin_tail_1 PF01576.14 KFP07983.1 - 2.9e-05 22.0 13.6 2.9e-05 22.0 9.4 2.7 3 0 0 3 3 3 1 Myosin tail CCDC155 PF14662.1 KFP07983.1 - 0.0026 17.3 18.3 0.0026 17.3 12.7 2.9 2 2 1 3 3 3 1 Coiled-coil region of CCDC155 DUF3450 PF11932.3 KFP07983.1 - 0.0064 15.7 3.9 0.0064 15.7 2.7 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF3450) BLOC1_2 PF10046.4 KFP07983.1 - 0.008 16.2 10.4 0.008 16.2 7.2 4.7 4 3 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KFP07983.1 - 0.0087 15.2 3.1 0.0087 15.2 2.1 2.4 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Vps51 PF08700.6 KFP07983.1 - 0.26 11.1 19.1 0.044 13.6 5.8 4.3 4 2 0 4 4 3 0 Vps51/Vps67 IncA PF04156.9 KFP07983.1 - 0.29 10.7 48.3 0.11 12.0 12.2 3.9 3 1 1 4 4 4 0 IncA protein Lzipper-MIP1 PF14389.1 KFP07983.1 - 0.99 9.5 29.1 0.73 9.9 3.0 5.1 5 0 0 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 CENP-F_leu_zip PF10473.4 KFP07983.1 - 1.3 8.8 44.6 0.28 11.0 6.2 4.4 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACR_tran PF00873.14 KFP07983.1 - 1.5 6.1 6.1 0.4 8.0 2.1 1.5 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family DUF1003 PF06210.6 KFP07983.1 - 3.4 7.6 17.9 2.7 7.9 1.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) DUF1664 PF07889.7 KFP07983.1 - 4.1 7.2 19.3 4.4 7.1 5.2 3.8 3 2 2 5 5 4 0 Protein of unknown function (DUF1664) ERM PF00769.14 KFP07983.1 - 6.3 6.2 38.4 0.046 13.2 11.2 2.7 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Baculo_IE-1 PF05290.6 KFP07983.1 - 6.5 6.4 8.9 7.9 6.2 0.4 3.1 3 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) NPV_P10 PF05531.7 KFP07983.1 - 9.9 6.4 17.5 1.5 9.1 0.1 4.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sin_N PF04801.8 KFP07984.1 - 8.3e-163 542.1 3.0 8.3e-163 542.1 2.1 1.7 3 0 0 3 3 3 1 Sin-like protein conserved region TORC_M PF12885.2 KFP07984.1 - 0.44 10.2 3.3 0.36 10.5 0.8 1.9 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain Alpha_kinase PF02816.13 KFP07985.1 - 7.5e-57 192.0 0.1 1.2e-56 191.3 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.7 KFP07985.1 - 4.5e-06 27.1 12.5 0.47 11.1 0.1 5.2 5 0 0 5 5 5 3 Sel1 repeat 3Beta_HSD PF01073.14 KFP07986.1 - 2e-67 226.8 0.0 2.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFP07986.1 - 8.4e-28 97.3 0.0 1.1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFP07986.1 - 4.2e-11 42.2 0.0 5.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFP07986.1 - 3e-09 36.1 0.0 4.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFP07986.1 - 3.4e-08 33.7 0.0 4.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFP07986.1 - 4.8e-08 32.2 0.4 2.2e-07 30.0 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KFP07986.1 - 6.2e-05 22.3 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KFP07986.1 - 0.17 11.8 0.3 0.46 10.3 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 KFP07987.1 - 3.3e-60 203.1 0.0 4e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFP07987.1 - 8.7e-25 87.5 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFP07987.1 - 5.7e-12 45.1 0.0 7.9e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFP07987.1 - 5.1e-07 28.8 0.0 3.1e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFP07987.1 - 1.5e-06 27.3 0.0 1.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFP07987.1 - 3.5e-05 23.8 0.0 4.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Bac_Ubq_Cox PF01654.12 KFP07988.1 - 1.2e-05 23.9 3.1 1.3e-05 23.7 2.2 1.1 1 0 0 1 1 1 1 Bacterial Cytochrome Ubiquinol Oxidase Claudin_2 PF13903.1 KFP07988.1 - 0.00016 21.4 4.7 0.00034 20.3 3.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TauE PF01925.14 KFP07988.1 - 0.038 13.4 5.3 0.046 13.1 3.7 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE L_HGMIC_fpl PF10242.4 KFP07988.1 - 0.055 13.4 5.3 0.093 12.7 3.5 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF998 PF06197.8 KFP07988.1 - 0.089 12.1 9.1 0.21 10.8 6.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Tetraspannin PF00335.15 KFP07988.1 - 0.17 11.1 7.6 0.22 10.7 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family SLAC1 PF03595.12 KFP07988.1 - 0.19 10.3 10.6 1.1 7.8 7.3 1.9 1 1 0 1 1 1 0 Voltage-dependent anion channel HlyIII PF03006.15 KFP07988.1 - 0.21 11.0 5.8 0.054 12.9 1.5 1.6 1 1 0 1 1 1 0 Haemolysin-III related DUF456 PF04306.8 KFP07988.1 - 0.24 11.4 8.9 0.12 12.4 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF2269 PF10027.4 KFP07988.1 - 0.56 9.9 4.8 0.99 9.1 3.3 1.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) 7TMR-DISM_7TM PF07695.6 KFP07988.1 - 1.7 8.2 13.0 4.4 6.9 8.2 1.8 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4131 PF13567.1 KFP07988.1 - 2.3 7.5 7.2 0.78 9.1 2.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF423 PF04241.10 KFP07988.1 - 3 7.8 6.3 0.36 10.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF1218 PF06749.7 KFP07988.1 - 4.3 7.8 6.9 1.7 9.1 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF202 PF02656.10 KFP07988.1 - 6.6 7.0 8.9 5.4e+02 0.9 6.2 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2975 PF11188.3 KFP07988.1 - 7.1 6.3 7.9 20 4.9 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2721 PF11026.3 KFP07988.1 - 7.4 6.2 10.3 3.8 7.1 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Peptidase_M16 PF00675.15 KFP07989.1 - 6.1e-31 107.1 0.0 9.9e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFP07989.1 - 1e-23 83.9 0.0 2.2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain OCD_Mu_crystall PF02423.10 KFP07990.1 - 1.5e-88 296.5 0.3 1.7e-88 296.4 0.2 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KFP07990.1 - 3.1e-08 33.8 0.0 4.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KFP07990.1 - 0.00021 21.6 0.1 0.00053 20.3 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFP07990.1 - 0.00023 21.0 0.5 0.0013 18.5 0.3 2.3 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ank_2 PF12796.2 KFP07991.1 - 3.9e-22 78.3 0.3 8.1e-18 64.5 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP07991.1 - 3.9e-18 64.2 1.8 2.3e-10 39.7 0.3 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFP07991.1 - 1.5e-17 63.2 2.8 4.2e-11 42.7 0.2 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP07991.1 - 1.3e-16 60.6 1.4 2.5e-08 34.2 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP07991.1 - 1.2e-13 49.7 0.4 1.1e-06 28.2 0.2 4.5 4 0 0 4 4 4 2 Ankyrin repeat SAM_1 PF00536.25 KFP07991.1 - 1.8e-07 31.2 0.0 4.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ribosomal_S18 PF01084.15 KFP07991.1 - 0.00063 19.5 0.2 0.0014 18.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 SAM_2 PF07647.12 KFP07991.1 - 0.0026 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Zona_pellucida PF00100.18 KFP07992.1 - 1.8e-51 175.1 0.1 6.5e-51 173.3 0.0 1.9 2 0 0 2 2 2 1 Zona pellucida-like domain CcmH PF03918.9 KFP07993.1 - 0.0075 15.2 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C biogenesis protein Hen1_L PF12623.2 KFP07993.1 - 0.095 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Dynein_heavy PF03028.10 KFP07994.1 - 7.9e-244 810.9 0.0 2.7e-243 809.1 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KFP07994.1 - 7.2e-138 459.4 9.6 7.2e-138 459.4 6.7 4.0 5 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KFP07994.1 - 1.2e-100 335.8 0.2 3.7e-100 334.2 0.1 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KFP07994.1 - 1.3e-68 230.8 0.7 2.6e-68 229.8 0.5 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KFP07994.1 - 1.6e-54 184.1 1.4 3.5e-54 183.0 1.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KFP07994.1 - 4.7e-54 183.3 0.0 9e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 KFP07994.1 - 3.5e-50 170.7 1.9 7.5e-50 169.6 1.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KFP07994.1 - 5.5e-23 81.2 0.0 2.9e-06 27.0 0.0 6.7 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFP07994.1 - 2.2e-06 27.8 0.5 0.085 13.0 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA PF00004.24 KFP07994.1 - 4.1e-06 27.0 1.3 0.38 10.9 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFP07994.1 - 4.4e-06 26.7 3.4 0.035 14.0 0.0 4.4 5 0 0 5 5 4 2 AAA ATPase domain RNA_helicase PF00910.17 KFP07994.1 - 6.8e-05 23.0 0.0 0.96 9.6 0.0 4.3 3 0 0 3 3 3 2 RNA helicase AAA_17 PF13207.1 KFP07994.1 - 7.1e-05 23.6 3.4 0.056 14.2 0.0 5.9 7 0 0 7 7 4 1 AAA domain T2SE PF00437.15 KFP07994.1 - 0.00088 18.2 1.6 0.0044 15.9 0.0 2.9 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_19 PF13245.1 KFP07994.1 - 0.0015 18.2 0.5 0.71 9.6 0.0 3.7 4 0 0 4 4 4 1 Part of AAA domain AAA_18 PF13238.1 KFP07994.1 - 0.003 17.8 0.0 2.2 8.5 0.0 4.5 4 0 0 4 4 3 1 AAA domain Sigma54_activ_2 PF14532.1 KFP07994.1 - 0.0044 17.0 0.1 8.6 6.4 0.0 4.4 4 0 0 4 4 4 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFP07994.1 - 0.053 12.6 0.3 8.8 5.4 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KFP07994.1 - 0.097 12.1 0.0 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 KFP07994.1 - 0.1 12.4 0.0 72 3.2 0.0 3.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 KFP07994.1 - 0.21 11.0 0.6 11 5.4 0.0 3.3 4 0 0 4 4 3 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KFP07994.1 - 1.2 8.5 2.5 39 3.5 0.0 3.7 4 0 0 4 4 4 0 AAA domain MerR-DNA-bind PF09278.6 KFP07994.1 - 3.7 8.0 8.9 19 5.7 2.9 3.6 2 0 0 2 2 2 0 MerR, DNA binding Complex1_LYR PF05347.10 KFP07995.1 - 3.6e-18 65.1 0.3 6.4e-18 64.3 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFP07995.1 - 7.4e-15 54.9 0.2 1.2e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFP07995.1 - 0.0014 19.0 0.8 0.003 18.0 0.2 1.7 2 0 0 2 2 2 1 Complex1_LYR-like Cullin_binding PF03556.10 KFP07996.1 - 2.8e-36 124.1 0.4 5e-36 123.3 0.3 1.4 1 0 0 1 1 1 1 Cullin binding RNase_T PF00929.19 KFP07997.1 - 2e-20 73.7 0.1 5.2e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Exonuclease RRM_1 PF00076.17 KFP07997.1 - 3e-18 65.2 0.0 9.3e-11 41.2 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP07997.1 - 6.1e-11 42.1 0.0 1.5e-06 28.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP07997.1 - 3e-05 23.7 0.0 0.0016 18.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EAV_GS PF01309.13 KFP07997.1 - 0.14 11.6 0.1 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein RNase_T PF00929.19 KFP07998.1 - 1.5e-19 70.8 0.0 2.4e-19 70.2 0.0 1.3 1 1 0 1 1 1 1 Exonuclease AMP-binding PF00501.23 KFP07999.1 - 1.7e-68 230.9 0.0 2.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFP07999.1 - 1.6e-20 73.8 1.2 2.6e-20 73.1 0.8 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SRI PF08236.6 KFP07999.1 - 0.059 13.3 1.1 0.12 12.3 0.7 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain THUMP PF02926.12 KFP08000.1 - 1.5e-23 83.2 0.4 3.2e-23 82.2 0.1 1.6 1 1 0 1 1 1 1 THUMP domain RNase_P_Rpp14 PF01900.14 KFP08000.1 - 0.021 14.6 0.0 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 Rpp14/Pop5 family DUF99 PF01949.11 KFP08000.1 - 0.055 12.5 0.2 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 VHL PF01847.11 KFP08000.1 - 0.058 12.9 0.2 0.094 12.2 0.1 1.3 1 0 0 1 1 1 0 von Hippel-Lindau disease tumour suppressor protein DUF1796 PF08795.5 KFP08000.1 - 0.068 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) AMP-binding PF00501.23 KFP08001.1 - 7.5e-81 271.6 0.0 9.7e-81 271.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFP08001.1 - 6.1e-22 78.3 0.7 1.1e-21 77.4 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KFP08002.1 - 4e-88 295.6 0.0 5.3e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFP08002.1 - 2.9e-21 76.1 1.3 6e-21 75.1 0.9 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7tm_1 PF00001.16 KFP08003.1 - 3.4e-23 82.1 21.1 4.2e-23 81.8 14.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SMAP PF15477.1 KFP08004.1 - 3.3e-19 68.9 3.6 3.3e-19 68.9 2.5 1.5 2 0 0 2 2 2 1 Small acidic protein family GDPD PF03009.12 KFP08006.1 - 2.6e-24 86.0 0.0 7.4e-24 84.6 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TMC PF07810.8 KFP08007.1 - 3.1e-37 127.3 1.2 3.1e-37 127.3 0.8 3.5 3 1 1 4 4 4 1 TMC domain LrgA PF03788.9 KFP08007.1 - 0.71 9.6 7.8 11 5.8 0.3 3.2 2 0 0 2 2 2 0 LrgA family TMC PF07810.8 KFP08009.1 - 9.1e-46 154.8 1.2 9.1e-46 154.8 0.9 2.5 2 0 0 2 2 2 1 TMC domain Pex24p PF06398.6 KFP08009.1 - 5.4 5.7 8.1 0.33 9.7 0.1 2.5 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin COQ7 PF03232.8 KFP08010.1 - 8.8e-80 266.1 0.0 1e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KFP08010.1 - 0.0056 16.9 0.1 0.028 14.7 0.1 1.9 1 1 0 1 1 1 1 Rubrerythrin PAH PF02671.16 KFP08010.1 - 0.15 11.6 0.3 0.42 10.2 0.1 1.8 2 0 0 2 2 2 0 Paired amphipathic helix repeat C2 PF00168.25 KFP08011.1 - 2.8e-40 136.0 0.1 7.8e-19 67.3 0.0 2.2 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 KFP08011.1 - 0.0018 17.9 0.7 0.07 12.7 0.1 2.6 1 1 1 2 2 2 2 C2 domain in Dock180 and Zizimin proteins Lectin_C PF00059.16 KFP08012.1 - 2.5e-19 69.8 0.4 3.1e-19 69.5 0.3 1.1 1 0 0 1 1 1 1 Lectin C-type domain PI3_PI4_kinase PF00454.22 KFP08013.1 - 3.8e-52 177.0 0.0 1.1e-51 175.5 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFP08013.1 - 2.4e-12 46.0 0.1 1e-11 44.0 0.0 2.2 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KFP08013.1 - 0.02 14.9 0.9 0.14 12.2 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Reticulon PF02453.12 KFP08014.1 - 2.5e-29 102.0 3.2 2.9e-29 101.8 2.2 1.0 1 0 0 1 1 1 1 Reticulon DUF1469 PF07332.6 KFP08014.1 - 0.17 11.6 1.5 7.2 6.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) VirB3 PF05101.8 KFP08014.1 - 0.18 11.8 3.5 0.59 10.1 0.0 2.5 2 1 1 3 3 3 0 Type IV secretory pathway, VirB3-like protein Ribosomal_S8 PF00410.14 KFP08015.1 - 1.6e-26 92.6 0.0 2.1e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Xylo_C PF12529.3 KFP08016.1 - 4.7e-69 231.3 0.0 8.8e-69 230.4 0.0 1.5 1 0 0 1 1 1 1 Xylosyltransferase C terminal Branch PF02485.16 KFP08016.1 - 1e-40 139.4 4.0 1.7e-40 138.7 2.8 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RNase_PH PF01138.16 KFP08017.1 - 1.1e-24 87.2 0.1 2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFP08017.1 - 1.1e-11 44.5 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glycos_transf_2 PF00535.21 KFP08018.1 - 4.9e-23 81.6 0.0 6.1e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFP08018.1 - 2.4e-09 37.3 0.0 7.5e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFP08018.1 - 9.3e-06 24.9 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MH2 PF03166.9 KFP08019.1 - 1.2e-77 259.8 0.3 1.6e-77 259.4 0.2 1.1 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.11 KFP08019.1 - 1.3e-42 144.0 1.2 2.9e-42 142.8 0.8 1.6 1 0 0 1 1 1 1 MH1 domain IRF-3 PF10401.4 KFP08019.1 - 2.2e-06 27.3 0.0 4.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Interferon-regulatory factor 3 DUF4223 PF13978.1 KFP08019.1 - 0.11 12.2 0.6 0.22 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Cyclin_N PF00134.18 KFP08021.1 - 6.2e-48 161.5 0.1 1.2e-47 160.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP08021.1 - 2.7e-31 107.9 0.9 6.9e-31 106.6 0.1 2.0 2 1 1 3 3 3 1 Cyclin, C-terminal domain DCX PF03607.12 KFP08022.1 - 1.8e-39 133.0 0.1 2e-24 84.9 0.0 2.4 2 0 0 2 2 2 2 Doublecortin Pkinase PF00069.20 KFP08023.1 - 3e-74 249.4 0.0 4.5e-74 248.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08023.1 - 4.9e-34 117.5 0.0 6.2e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP08023.1 - 0.00015 20.8 0.0 0.00033 19.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP08023.1 - 0.00086 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFP08023.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFP08023.1 - 0.12 11.7 0.2 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Macoilin PF09726.4 KFP08023.1 - 6.7 4.8 7.2 10 4.2 5.0 1.2 1 0 0 1 1 1 0 Transmembrane protein RVT_1 PF00078.22 KFP08024.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Mab-21 PF03281.9 KFP08025.1 - 1.4e-89 300.1 0.0 2.1e-89 299.5 0.0 1.3 1 0 0 1 1 1 1 Mab-21 protein Rep_fac_C PF08542.6 KFP08026.1 - 2.2e-23 82.0 0.3 1.1e-22 79.8 0.0 2.3 4 0 0 4 4 4 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFP08026.1 - 4e-10 39.5 0.1 9.5e-10 38.3 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 KFP08026.1 - 1.1e-06 28.2 0.0 2.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KFP08026.1 - 3.9e-06 27.0 0.0 8.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP08026.1 - 2.2e-05 24.6 0.5 0.00011 22.2 0.2 2.2 1 1 2 3 3 3 1 AAA domain ABC_tran PF00005.22 KFP08026.1 - 0.0097 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 KFP08026.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain Bac_DnaA PF00308.13 KFP08026.1 - 0.044 13.4 0.1 0.35 10.4 0.0 2.2 2 1 0 2 2 2 0 Bacterial dnaA protein Rad17 PF03215.10 KFP08026.1 - 0.048 12.3 0.1 0.071 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KFP08026.1 - 0.07 13.1 0.2 0.24 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 KFP08026.1 - 0.076 13.0 0.2 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain START PF01852.14 KFP08027.1 - 3.8e-41 140.6 0.4 6.7e-41 139.8 0.2 1.4 1 0 0 1 1 1 1 START domain RhoGAP PF00620.22 KFP08027.1 - 3.9e-36 123.9 0.9 7.5e-36 123.0 0.6 1.4 1 0 0 1 1 1 1 RhoGAP domain Ribosomal_S5_C PF03719.10 KFP08027.1 - 0.23 10.7 0.0 0.53 9.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Glyco_hydro_1 PF00232.13 KFP08028.1 - 6.1e-143 476.3 14.5 2.2e-73 246.9 3.4 4.0 2 2 1 3 3 3 3 Glycosyl hydrolase family 1 HEAT_2 PF13646.1 KFP08029.1 - 4.4e-07 30.0 2.2 0.77 10.0 0.0 6.0 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.17 KFP08029.1 - 1.6e-05 24.5 4.2 11 6.4 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.2 KFP08029.1 - 0.12 12.2 18.8 0.31 10.8 1.2 6.0 4 2 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFP08029.1 - 0.24 11.9 3.7 1.5e+02 3.0 0.0 5.8 7 0 0 7 7 7 0 HEAT-like repeat AAA_33 PF13671.1 KFP08030.1 - 5.9e-20 71.5 0.0 1.5e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFP08030.1 - 1.3e-06 27.6 0.0 4.1e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KFP08030.1 - 5.7e-05 23.9 0.0 0.00017 22.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFP08030.1 - 8.7e-05 22.8 0.4 0.0096 16.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KFP08030.1 - 0.00026 20.2 2.2 0.00044 19.5 0.0 2.4 2 1 0 2 2 2 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 KFP08030.1 - 0.0089 16.3 0.7 0.083 13.1 0.0 2.6 3 0 0 3 3 3 1 ABC transporter Viral_helicase1 PF01443.13 KFP08030.1 - 0.037 13.5 0.1 0.26 10.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KFP08030.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KFP08030.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain BRCA-2_helical PF09169.5 KFP08032.1 - 2.2e-94 314.5 0.2 1.1e-93 312.2 0.0 2.4 2 0 0 2 2 2 1 BRCA2, helical BRCA-2_OB3 PF09104.5 KFP08032.1 - 5.5e-64 214.2 0.5 6.6e-63 210.7 0.0 2.8 3 0 0 3 3 3 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 BRCA2 PF00634.13 KFP08032.1 - 4.1e-48 160.1 20.2 8.7e-11 40.8 0.1 7.3 7 0 0 7 7 7 6 BRCA2 repeat BRCA-2_OB1 PF09103.5 KFP08032.1 - 8.4e-41 138.3 0.0 1.9e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Tower PF09121.5 KFP08032.1 - 6.1e-22 77.2 4.9 1.7e-21 75.8 3.4 1.9 1 0 0 1 1 1 1 Tower zf-3CxxC PF13695.1 KFP08033.1 - 1.6e-18 66.6 19.3 2e-18 66.4 13.4 1.1 1 0 0 1 1 1 1 Zinc-binding domain FYVE_2 PF02318.11 KFP08033.1 - 3.4 7.6 18.9 0.38 10.6 9.6 1.8 1 1 1 2 2 2 0 FYVE-type zinc finger DNA_RNApol_7kD PF03604.8 KFP08033.1 - 5.9 6.4 15.1 0.17 11.4 1.3 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 KFP08033.1 - 6.6 6.4 19.5 1.9 8.2 4.8 3.0 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family dUTPase PF00692.14 KFP08034.1 - 1.3e-14 53.7 0.0 2.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 dUTPase RVP PF00077.15 KFP08034.1 - 0.042 13.7 0.6 0.075 12.9 0.1 1.6 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-C2H2 PF00096.21 KFP08035.1 - 1.2e-11 44.2 6.6 3.1e-07 30.3 0.2 2.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08035.1 - 3e-09 36.5 3.8 1.8e-05 24.7 0.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFP08035.1 - 4e-08 33.1 12.1 3e-06 27.2 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFP08035.1 - 2.1e-07 30.5 5.1 1e-05 25.2 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP08035.1 - 0.0002 21.3 2.0 0.042 14.0 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP08035.1 - 0.0022 18.1 3.4 0.036 14.2 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KFP08035.1 - 0.01 15.7 1.3 2.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain UPF0547 PF10571.4 KFP08035.1 - 0.02 14.5 1.1 0.47 10.2 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 BolA PF01722.13 KFP08035.1 - 0.09 12.7 1.1 0.1 12.5 0.8 1.1 1 0 0 1 1 1 0 BolA-like protein zf-LYAR PF08790.6 KFP08035.1 - 0.11 12.1 4.3 0.51 10.0 0.4 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger XPA_N PF01286.13 KFP08035.1 - 0.23 11.1 1.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_2 PF13240.1 KFP08035.1 - 0.39 10.2 1.8 7.6 6.1 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_5 PF13909.1 KFP08035.1 - 5.4 7.4 7.3 5.2 7.5 0.1 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain RHD PF00554.17 KFP08036.1 - 7.9e-71 237.2 0.0 1.5e-70 236.2 0.0 1.5 1 0 0 1 1 1 1 Rel homology domain (RHD) Ank_2 PF12796.2 KFP08036.1 - 1.8e-48 162.7 24.4 2.1e-15 56.8 1.6 4.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFP08036.1 - 3.1e-34 115.0 12.1 1.8e-07 30.6 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFP08036.1 - 2.5e-24 85.1 5.9 4.8e-08 33.3 0.0 5.3 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP08036.1 - 5.3e-23 78.7 8.5 0.00023 21.0 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KFP08036.1 - 3.6e-22 77.8 8.4 2.2e-08 34.0 0.1 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Death PF00531.17 KFP08036.1 - 5.7e-12 45.2 0.0 1.7e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Death domain Glyco_hydro_2_C PF02836.12 KFP08037.1 - 1.8e-08 33.6 0.0 3.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KFP08037.1 - 1.1e-06 28.2 0.1 3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain FANCI_S3 PF14677.1 KFP08037.1 - 0.057 12.8 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 FANCI solenoid 3 DUF4131 PF13567.1 KFP08037.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) UQ_con PF00179.21 KFP08038.1 - 4e-48 162.4 0.0 4.3e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP08038.1 - 0.00018 21.3 0.0 0.0002 21.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFP08038.1 - 0.0021 17.9 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFP08038.1 - 0.034 13.8 0.1 0.054 13.1 0.1 1.3 1 1 0 1 1 1 0 UEV domain zf-CDGSH PF09360.5 KFP08039.1 - 2.8e-10 39.8 0.5 4.9e-10 39.0 0.4 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type MitoNEET_N PF10660.4 KFP08039.1 - 3.9e-09 36.2 0.0 5.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus DUF1154 PF06631.6 KFP08039.1 - 1.6 8.4 0.0 1.6 8.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1154) Pkinase PF00069.20 KFP08040.1 - 3.6e-63 213.1 0.0 4.8e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08040.1 - 1.7e-31 109.2 0.0 2.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Activin_recp PF01064.18 KFP08040.1 - 6.1e-08 33.2 10.8 6.1e-08 33.2 7.5 2.4 2 0 0 2 2 2 1 Activin types I and II receptor domain APH PF01636.18 KFP08040.1 - 0.04 13.6 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PWWP PF00855.12 KFP08041.1 - 0.00054 20.1 0.1 0.0018 18.4 0.1 1.9 1 1 0 1 1 1 1 PWWP domain MBD PF01429.14 KFP08041.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyl-CpG binding domain Kinesin PF00225.18 KFP08042.1 - 1.2e-110 369.4 0.3 1.2e-110 369.4 0.2 2.6 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 KFP08042.1 - 0.83 8.7 24.1 0.094 11.8 2.4 4.0 1 1 1 4 4 4 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 KFP08042.1 - 5.9 6.7 10.1 21 4.9 0.5 4.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 RVT_1 PF00078.22 KFP08044.1 - 0.043 13.1 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2246 PF10229.4 KFP08046.1 - 2.9e-128 427.0 0.0 3.2e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) Yae1_N PF09811.4 KFP08047.1 - 5.4e-09 35.4 53.9 1.5e+04 -22.6 37.4 4.1 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Ras PF00071.17 KFP08048.1 - 7.3e-43 145.7 0.0 9.8e-43 145.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP08048.1 - 1.5e-16 60.9 0.0 2.6e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP08048.1 - 6.3e-07 28.7 0.0 9.2e-07 28.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFP08048.1 - 0.016 14.4 0.0 0.046 12.9 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KFP08048.1 - 0.032 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 KFP08048.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KFP08048.1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFP08048.1 - 0.037 13.5 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFP08048.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NID PF07292.8 KFP08049.1 - 8.3e-12 45.0 0.1 9.7e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_6 PF14259.1 KFP08049.1 - 2.8e-05 24.0 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP08049.1 - 0.00093 18.7 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP08049.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 KFP08050.1 - 3.5e-36 123.1 0.0 2e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 Nmi/IFP 35 domain (NID) RRM_6 PF14259.1 KFP08050.1 - 1.6e-05 24.8 0.0 0.4 10.6 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CUB PF00431.15 KFP08051.1 - 1.8e-36 124.5 0.1 3.2e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 CUB domain Xlink PF00193.12 KFP08051.1 - 1.2e-32 111.8 1.7 2.1e-32 111.0 1.2 1.4 1 0 0 1 1 1 1 Extracellular link domain Rif1_N PF12231.3 KFP08052.1 - 1.9e-83 280.4 6.1 1.9e-83 280.4 4.2 2.0 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal HtaA PF04213.8 KFP08052.1 - 0.016 15.4 3.0 0.24 11.6 0.1 2.7 2 0 0 2 2 2 0 Htaa Arf PF00025.16 KFP08053.1 - 1.6e-64 216.3 0.9 1.8e-64 216.2 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFP08053.1 - 2.8e-14 52.8 0.4 3.1e-14 52.7 0.3 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP08053.1 - 2.9e-12 46.1 0.3 3.5e-12 45.9 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFP08053.1 - 3.4e-11 43.6 0.1 4.5e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KFP08053.1 - 3.5e-08 32.5 1.0 1.1e-05 24.2 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 KFP08053.1 - 1.1e-07 31.8 0.2 1.4e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP08053.1 - 1.7e-07 30.6 0.4 2.1e-07 30.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP08053.1 - 0.00013 21.4 0.3 0.00092 18.6 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFP08053.1 - 0.0062 16.4 0.2 0.034 14.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 KFP08053.1 - 0.052 12.8 0.9 0.25 10.6 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Octopine_DH PF02317.12 KFP08053.1 - 0.055 13.1 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain VHS PF00790.14 KFP08054.1 - 5.1e-38 129.8 0.8 4e-37 127.0 0.0 2.3 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 KFP08054.1 - 8.5e-19 66.6 0.1 1.6e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP08054.1 - 8.9e-14 50.8 0.1 1.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP08054.1 - 9.3e-12 44.2 0.0 1.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KFP08054.1 - 4.5e-05 22.6 0.8 0.00011 21.4 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif ZapA PF05164.8 KFP08054.1 - 0.023 14.6 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapA VanY PF02557.12 KFP08054.1 - 0.049 13.4 0.7 3.3 7.5 0.0 2.8 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase FAM70 PF14967.1 KFP08054.1 - 1.4 8.0 7.7 0.85 8.7 0.8 2.3 2 0 0 2 2 2 0 FAM70 protein A2M_comp PF07678.9 KFP08055.1 - 4.4e-81 271.7 1.8 7.8e-81 270.9 1.2 1.4 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 KFP08055.1 - 1.8e-37 128.1 0.6 4.9e-35 120.2 0.0 3.2 2 1 0 2 2 2 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 KFP08055.1 - 1.6e-29 101.2 0.1 5e-29 99.7 0.1 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_recep PF07677.9 KFP08055.1 - 2.8e-26 91.5 1.6 9.1e-26 89.8 1.1 2.0 1 0 0 1 1 1 1 A-macroglobulin receptor A2M_N PF01835.14 KFP08055.1 - 5.2e-24 84.3 0.3 6.6e-22 77.6 0.0 3.9 4 0 0 4 4 4 1 MG2 domain Thiol-ester_cl PF10569.4 KFP08055.1 - 6.3e-17 60.5 1.3 1.7e-16 59.1 0.9 1.8 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 KFP08055.1 - 2.2e-13 50.6 1.5 6.5e-09 36.1 0.0 3.6 1 1 2 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFP08055.1 - 1.2e-05 25.2 0.5 0.031 14.2 0.1 2.5 2 0 0 2 2 2 2 Prenyltransferase-like SVA PF05326.6 KFP08055.1 - 0.00067 19.4 0.1 0.002 17.8 0.0 1.8 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) MG1 PF11974.3 KFP08055.1 - 0.0014 19.1 0.1 1.1 9.8 0.0 3.8 3 1 1 4 4 4 1 Alpha-2-macroglobulin MG1 domain Prenyltrans PF00432.16 KFP08055.1 - 0.071 12.6 3.5 0.072 12.6 0.0 2.9 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Big_1 PF02369.11 KFP08055.1 - 0.079 12.8 0.4 0.41 10.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) A2M_N_2 PF07703.9 KFP08056.1 - 7.3e-34 116.4 0.9 1.9e-32 111.9 0.1 3.2 4 1 0 4 4 4 1 Alpha-2-macroglobulin family N-terminal region A2M_comp PF07678.9 KFP08056.1 - 2e-28 99.2 0.2 2.9e-28 98.7 0.1 1.2 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 KFP08056.1 - 2.3e-28 97.5 0.1 1.1e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N PF01835.14 KFP08056.1 - 4.5e-22 78.1 0.1 3e-21 75.5 0.0 2.6 2 0 0 2 2 2 1 MG2 domain Thiol-ester_cl PF10569.4 KFP08056.1 - 1.3e-16 59.5 0.7 6.4e-16 57.2 0.4 2.4 2 0 0 2 2 2 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 KFP08056.1 - 0.0011 19.3 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase-like SVA PF05326.6 KFP08056.1 - 0.0018 18.0 0.3 0.0069 16.1 0.0 2.2 2 0 0 2 2 2 1 Seminal vesicle autoantigen (SVA) DUF2628 PF10947.3 KFP08056.1 - 0.032 14.0 0.2 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) A2M_comp PF07678.9 KFP08057.1 - 4.7e-41 140.6 0.0 7.5e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_N_2 PF07703.9 KFP08057.1 - 3.4e-31 107.8 0.1 2.8e-29 101.6 0.0 2.7 2 0 0 2 2 2 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 KFP08057.1 - 2.8e-30 103.7 0.8 6e-30 102.6 0.1 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N PF01835.14 KFP08057.1 - 6.5e-18 64.8 0.1 2e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 MG2 domain Thiol-ester_cl PF10569.4 KFP08057.1 - 1.7e-16 59.1 0.9 3.7e-16 58.0 0.6 1.7 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region Prenyltrans_2 PF13249.1 KFP08057.1 - 9.9e-05 22.7 0.0 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase-like SVA PF05326.6 KFP08057.1 - 0.0029 17.3 1.4 0.0072 16.1 0.0 2.3 3 0 0 3 3 3 1 Seminal vesicle autoantigen (SVA) CarboxypepD_reg PF13620.1 KFP08057.1 - 0.024 14.6 0.4 0.84 9.7 0.0 2.9 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Big_1 PF02369.11 KFP08057.1 - 0.03 14.2 2.6 0.24 11.3 0.2 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) SAM_1 PF00536.25 KFP08058.1 - 1.2e-16 60.6 0.0 2.6e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP08058.1 - 1.8e-10 40.5 0.0 3.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-FCS PF06467.9 KFP08058.1 - 4.2e-06 26.3 2.4 8.4e-06 25.3 1.7 1.6 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif SAM_PNT PF02198.11 KFP08058.1 - 0.0034 17.1 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain A2M_comp PF07678.9 KFP08059.1 - 8.7e-34 116.8 0.0 1.3e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 A-macroglobulin complement component A2M PF00207.17 KFP08059.1 - 5.5e-24 83.5 0.2 2.9e-23 81.2 0.0 2.2 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 KFP08059.1 - 7.4e-18 64.6 0.0 2.3e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family N-terminal region Thiol-ester_cl PF10569.4 KFP08059.1 - 6.9e-17 60.3 1.3 1.4e-16 59.4 0.2 2.1 2 0 0 2 2 2 1 Alpha-macro-globulin thiol-ester bond-forming region SVA PF05326.6 KFP08059.1 - 3.6e-10 39.6 0.8 8.7e-10 38.4 0.5 1.6 1 0 0 1 1 1 1 Seminal vesicle autoantigen (SVA) Prenyltrans_2 PF13249.1 KFP08059.1 - 0.00084 19.7 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFP08059.1 - 0.0055 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Prenyltransferase-like MAGP PF05507.6 KFP08060.1 - 1.2e-28 99.6 9.0 1.2e-28 99.6 6.2 1.5 2 0 0 2 2 2 1 Microfibril-associated glycoprotein (MAGP) SVWC PF15430.1 KFP08060.1 - 1.3 9.5 4.7 2 8.9 1.3 2.3 1 1 1 2 2 2 0 Single domain von Willebrand factor type C Gliadin PF13016.1 KFP08060.1 - 2.5 8.3 10.3 2.5 8.3 1.9 2.2 1 1 1 2 2 2 0 Cys-rich Gliadin N-terminal APOBEC_N PF08210.6 KFP08061.1 - 3.3e-48 163.8 0.2 3.8e-48 163.6 0.2 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 KFP08061.1 - 7.7e-23 79.6 0.1 1.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain Toxin-deaminase PF14424.1 KFP08061.1 - 0.058 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases RcbX PF02341.10 KFP08061.1 - 0.11 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 RbcX protein APOBEC_N PF08210.6 KFP08062.1 - 1.9e-25 89.6 0.0 2.1e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 KFP08062.1 - 4.5e-11 41.9 1.0 5.3e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 APOBEC-like C-terminal domain Toxin-deaminase PF14424.1 KFP08062.1 - 0.057 13.3 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases dCMP_cyt_deam_1 PF00383.17 KFP08062.1 - 0.066 12.8 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region H_lectin PF09458.5 KFP08062.1 - 0.081 12.5 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 H-type lectin domain APOBEC_N PF08210.6 KFP08063.1 - 8.8e-12 45.0 2.7 9.4e-12 44.9 1.9 1.0 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC_C PF05240.9 KFP08063.1 - 0.017 14.5 0.1 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Homeobox PF00046.24 KFP08064.1 - 4.6e-21 74.1 5.5 1e-20 73.0 3.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP08064.1 - 8.8e-05 21.4 0.5 0.00017 20.6 0.4 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFP08064.1 - 0.0014 18.3 2.9 0.014 15.0 2.0 2.5 1 1 0 1 1 1 1 Homeobox KN domain Pro-kuma_activ PF09286.6 KFP08064.1 - 0.0016 18.4 0.3 0.0039 17.2 0.2 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain HlyD PF00529.15 KFP08064.1 - 0.05 12.8 2.1 0.07 12.4 1.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Homeobox PF00046.24 KFP08065.1 - 3e-22 77.9 5.1 4.7e-22 77.3 3.5 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KFP08065.1 - 9.8e-06 24.5 0.5 1.7e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KFP08065.1 - 0.0014 18.2 0.1 0.0032 17.1 0.1 1.7 1 1 0 1 1 1 1 Homeobox KN domain Pro-kuma_activ PF09286.6 KFP08065.1 - 0.0018 18.3 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Antimicrobial21 PF14861.1 KFP08065.1 - 0.017 14.6 4.4 0.028 13.8 3.0 1.4 1 0 0 1 1 1 0 Plant antimicrobial peptide Cortex-I_coil PF09304.5 KFP08065.1 - 0.14 12.2 0.4 0.18 11.8 0.3 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil Sugar_tr PF00083.19 KFP08066.1 - 6.4e-160 532.6 26.9 7.3e-160 532.4 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP08066.1 - 4.6e-21 74.9 31.7 1.3e-19 70.1 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFP08066.1 - 9.1e-06 24.3 35.6 3.1e-05 22.5 2.2 3.5 1 1 0 3 3 3 2 MFS/sugar transport protein Phage_holin_2 PF04550.7 KFP08066.1 - 1.6 8.8 10.9 0.23 11.5 3.9 2.4 2 1 1 3 3 3 0 Phage holin family 2 YlaC PF10777.4 KFP08066.1 - 3.7 7.0 5.1 3.5 7.1 0.2 2.8 2 1 1 3 3 3 0 Inner membrane protein YlaC Fork_head PF00250.13 KFP08067.1 - 8.3e-37 125.1 0.1 3e-36 123.3 0.1 1.9 1 0 0 1 1 1 1 Fork head domain DUF1681 PF07933.9 KFP08068.1 - 3.1e-64 215.3 0.0 3.8e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Lectin_C PF00059.16 KFP08069.1 - 3.1e-11 43.8 1.4 7.6e-11 42.5 0.2 2.1 1 1 1 2 2 2 1 Lectin C-type domain Chordopox_A33R PF05966.7 KFP08069.1 - 0.037 12.7 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Lectin_C PF00059.16 KFP08070.1 - 3.4e-12 46.9 1.7 3.8e-12 46.7 0.3 1.6 1 1 1 2 2 2 1 Lectin C-type domain Chordopox_A33R PF05966.7 KFP08070.1 - 0.073 11.8 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein M60-like PF13402.1 KFP08071.1 - 1e-87 293.9 0.0 1.5e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M60-like family Lact_bio_phlase PF09508.5 KFP08071.1 - 0.0025 15.5 0.0 0.56 7.8 0.0 2.6 3 0 0 3 3 3 2 Lacto-N-biose phosphorylase FKBP_C PF00254.23 KFP08072.1 - 1.1e-47 159.9 0.1 3.5e-31 107.0 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 KFP08072.1 - 6.6e-23 80.1 14.7 1.1e-13 50.6 0.9 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFP08072.1 - 7.1e-18 63.3 10.8 5.8e-09 35.1 1.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP08072.1 - 1.7e-14 52.4 12.8 5.3e-06 25.9 0.8 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFP08072.1 - 5e-09 35.3 6.0 2.6e-05 23.6 0.6 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP08072.1 - 8.5e-08 32.6 0.7 0.038 14.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFP08072.1 - 1.3e-07 31.5 3.2 0.011 16.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP08072.1 - 2.8e-07 30.7 2.2 0.0002 21.6 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFP08072.1 - 9e-07 28.7 11.6 0.00014 21.7 0.9 3.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP08072.1 - 3.9e-06 27.0 0.1 0.018 15.6 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFP08072.1 - 1.8e-05 24.1 3.8 0.012 15.3 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFP08072.1 - 0.0015 18.4 0.2 0.0015 18.4 0.2 3.0 3 1 1 4 4 2 1 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 KFP08072.1 - 0.0078 16.0 0.3 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_9 PF13371.1 KFP08072.1 - 0.01 15.6 0.1 0.042 13.7 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFP08072.1 - 0.014 15.5 5.1 0.26 11.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFP08072.1 - 0.022 14.8 7.1 0.073 13.2 4.0 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 KFP08072.1 - 3.9 7.4 7.1 0.61 10.0 1.0 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat BBS2_Mid PF14783.1 KFP08073.1 - 2.1e-12 46.7 0.6 0.00039 20.1 0.0 3.4 3 0 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 KFP08073.1 - 0.00041 19.9 0.4 0.81 9.4 0.0 3.7 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.1 KFP08073.1 - 0.0021 18.4 1.7 0.31 11.4 0.1 3.5 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Asp_protease PF09668.5 KFP08074.1 - 2.5e-09 36.7 0.1 3.8e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KFP08074.1 - 0.0096 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KFP08074.1 - 0.035 14.6 0.0 0.057 13.9 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Fork_head PF00250.13 KFP08075.1 - 1.6e-27 95.4 0.4 3.4e-27 94.3 0.2 1.5 1 0 0 1 1 1 1 Fork head domain RHINO PF15319.1 KFP08076.1 - 2.5e-64 217.3 10.2 2.8e-64 217.1 7.1 1.0 1 0 0 1 1 1 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein LIN37 PF15306.1 KFP08076.1 - 0.062 13.2 0.2 0.062 13.2 0.1 2.0 2 0 0 2 2 2 0 LIN37 Tub PF01167.13 KFP08077.1 - 2.1e-116 387.1 0.0 2.9e-116 386.7 0.0 1.2 1 0 0 1 1 1 1 Tub family TEA PF01285.13 KFP08078.1 - 2.7e-177 590.2 0.2 3.4e-177 589.9 0.1 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 KFP08078.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Tetraspannin PF00335.15 KFP08079.1 - 1.1e-44 152.4 12.6 1.2e-44 152.2 8.8 1.0 1 0 0 1 1 1 1 Tetraspanin family Baculo_11_kDa PF06143.6 KFP08079.1 - 0.073 12.4 0.8 0.18 11.2 0.5 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family ODV-E18 PF10717.4 KFP08079.1 - 0.17 11.3 1.7 0.24 10.8 0.2 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Claudin_2 PF13903.1 KFP08079.1 - 0.25 11.0 8.3 0.074 12.7 3.3 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction EF-hand_7 PF13499.1 KFP08080.1 - 5.5e-11 42.4 0.2 3.9e-07 30.0 0.0 3.6 3 1 1 4 4 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP08080.1 - 6.8e-09 34.4 0.0 0.00091 18.3 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP08080.1 - 9.3e-09 34.4 0.1 0.0061 16.3 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFP08080.1 - 1.6e-06 27.6 0.1 1.9e-05 24.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFP08080.1 - 5.6e-05 22.2 0.1 0.028 13.7 0.0 3.3 2 0 0 2 2 2 1 EF hand Nup54 PF13874.1 KFP08080.1 - 0.023 14.3 21.9 1.3 8.6 2.1 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 SpoIIAA-like PF11964.3 KFP08080.1 - 0.047 13.9 0.2 4.2 7.7 0.0 2.7 2 0 0 2 2 2 0 SpoIIAA-like LMP PF04778.7 KFP08080.1 - 0.09 12.5 14.1 0.02 14.6 6.4 2.2 1 1 1 2 2 2 0 LMP repeated region Plasmod_Pvs28 PF06247.6 KFP08080.1 - 0.16 11.4 0.1 0.16 11.4 0.0 2.5 2 1 1 3 3 3 0 Plasmodium ookinete surface protein Pvs28 FTCD_C PF04961.7 KFP08080.1 - 3.6 6.9 7.5 1.4 8.2 3.0 1.9 1 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase ArdA PF07275.6 KFP08080.1 - 4.1 7.6 12.6 3.9 7.7 7.1 2.2 1 1 1 2 2 2 0 Antirestriction protein (ArdA) GAGA_bind PF06217.7 KFP08080.1 - 4.7 7.0 11.6 7.3 6.4 8.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Phage_Mu_Gam PF07352.7 KFP08080.1 - 7.6 6.0 20.5 0.22 11.0 0.6 2.8 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Ras PF00071.17 KFP08081.1 - 6.6e-44 149.1 0.1 7.3e-44 149.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP08081.1 - 3.4e-21 75.9 0.1 3.9e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP08081.1 - 3.2e-17 62.3 0.1 3.8e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP08081.1 - 5e-09 36.1 0.1 6.1e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFP08081.1 - 3.1e-07 29.7 0.0 3.6e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFP08081.1 - 4.1e-05 22.8 0.0 5.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KFP08081.1 - 0.00014 21.3 0.0 0.00074 19.0 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFP08081.1 - 0.0052 16.6 0.0 0.078 12.7 0.0 1.9 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 KFP08081.1 - 0.015 14.5 0.1 0.019 14.2 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 KFP08081.1 - 0.037 12.7 0.7 5 5.6 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.24 KFP08081.1 - 0.037 14.2 0.0 0.057 13.6 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KFP08081.1 - 0.04 13.4 0.1 0.89 9.0 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KFP08081.1 - 0.041 14.0 0.0 0.065 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFP08081.1 - 0.05 13.4 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFP08081.1 - 0.081 13.7 0.0 0.089 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KFP08081.1 - 0.083 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin EIIA-man PF03610.11 KFP08081.1 - 0.097 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 PTS system fructose IIA component OKR_DC_1_N PF03709.10 KFP08081.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PrmA PF06325.8 KFP08082.1 - 1.7e-09 37.2 0.0 2.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFP08082.1 - 1.8e-07 30.8 0.1 3.3e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KFP08082.1 - 6.1e-07 28.7 0.3 8e-07 28.3 0.2 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 KFP08082.1 - 1.3e-06 28.4 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP08082.1 - 2.1e-06 28.3 0.0 4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP08082.1 - 4e-06 27.2 0.0 8.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KFP08082.1 - 2.5e-05 23.9 0.1 4.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 KFP08082.1 - 7e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP08082.1 - 0.00011 21.5 0.1 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 KFP08082.1 - 0.00091 18.5 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_9 PF08003.6 KFP08082.1 - 0.0033 16.1 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KFP08082.1 - 0.0056 17.1 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFP08082.1 - 0.0092 15.4 0.1 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 KFP08082.1 - 0.01 15.3 0.2 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFP08082.1 - 0.02 13.9 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PNRC PF15365.1 KFP08082.1 - 0.021 14.8 1.2 0.044 13.8 0.8 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Methyltransf_4 PF02390.12 KFP08082.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 KFP08082.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KFP08082.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase RasGAP PF00616.14 KFP08085.1 - 2.4e-42 144.8 0.5 4.3e-42 144.0 0.3 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KFP08085.1 - 5.2e-09 35.8 0.2 1.5e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 C2 domain IL11 PF07400.6 KFP08085.1 - 0.052 13.0 0.1 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 11 zf-C2H2_jaz PF12171.3 KFP08085.1 - 0.11 12.6 0.4 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BTB PF00651.26 KFP08086.1 - 1.4e-24 86.1 0.5 4.5e-24 84.5 0.3 1.9 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFP08086.1 - 1.6e-16 59.7 53.9 1.8e-06 27.9 5.7 7.6 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08086.1 - 2.3e-11 43.3 61.6 0.015 15.6 0.2 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08086.1 - 4.1e-11 42.4 56.0 0.008 16.4 4.0 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.2 KFP08086.1 - 1.4e-06 28.3 5.8 0.00046 20.3 0.7 6.7 7 0 0 7 7 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP08086.1 - 2.6e-05 24.2 46.3 0.00053 20.0 0.4 6.7 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KFP08086.1 - 0.0016 18.0 1.1 2.3 7.8 0.0 3.7 3 0 0 3 3 3 1 GAGA factor zf-C2H2_6 PF13912.1 KFP08086.1 - 0.011 15.5 36.8 0.4 10.6 0.1 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFP08086.1 - 0.017 14.7 17.4 0.37 10.5 0.6 5.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-AD PF07776.10 KFP08086.1 - 0.098 12.6 12.6 0.85 9.6 0.0 4.3 4 1 0 4 4 4 0 Zinc-finger associated domain (zf-AD) zf-C2H2_2 PF12756.2 KFP08086.1 - 1.8 8.7 37.5 1.9 8.6 1.0 6.6 2 2 4 6 6 6 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 KFP08086.1 - 7.7 6.5 25.9 2.7 8.0 3.1 5.3 3 2 0 3 3 3 0 Zinc ribbon domain TMF_TATA_bd PF12325.3 KFP08088.1 - 0.0049 16.5 14.2 0.0049 16.5 9.8 7.0 2 1 4 6 6 6 3 TATA element modulatory factor 1 TATA binding LPP PF04728.8 KFP08088.1 - 0.019 14.7 7.4 0.093 12.5 0.3 3.8 3 1 1 4 4 4 0 Lipoprotein leucine-zipper FtsA PF14450.1 KFP08088.1 - 8.1 6.3 9.4 9 6.1 1.4 3.4 1 1 0 2 2 2 0 Cell division protein FtsA zf-HC5HC2H_2 PF13832.1 KFP08089.1 - 1.1e-33 115.5 3.0 1.1e-33 115.5 2.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFP08089.1 - 3.6e-28 97.5 2.2 3.6e-28 97.5 1.5 4.0 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.4 KFP08089.1 - 5e-21 75.6 0.1 5e-21 75.6 0.0 3.5 2 1 1 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 KFP08089.1 - 5.2e-13 48.0 6.3 5.2e-13 48.0 4.4 3.6 3 1 1 4 4 4 1 PHD-finger PHD PF00628.24 KFP08089.1 - 1.2e-11 44.1 23.3 1.1e-09 37.7 6.2 3.3 3 0 0 3 3 3 2 PHD-finger zf-RING-like PF08746.6 KFP08089.1 - 0.0061 16.5 2.8 0.0061 16.5 1.9 3.6 2 1 1 3 3 3 1 RING-like domain C1_1 PF00130.17 KFP08089.1 - 0.0063 16.2 5.1 0.0063 16.2 3.5 3.4 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KFP08089.1 - 0.042 13.5 15.3 0.94 9.2 1.1 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 La PF05383.12 KFP08090.1 - 6.1e-23 80.3 0.1 1.5e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 La domain API5 PF05918.6 KFP08090.1 - 1.8 6.9 9.0 2.8 6.3 6.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2048 PF09752.4 KFP08091.1 - 2.1e-148 493.8 0.0 2.4e-148 493.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 KFP08091.1 - 1.2e-06 28.5 0.0 1.8e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFP08091.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KFP08091.1 - 0.042 13.2 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Phage_antitermQ PF06530.7 KFP08091.1 - 0.042 13.4 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Phage antitermination protein Q Abhydrolase_1 PF00561.15 KFP08091.1 - 0.05 13.1 0.1 0.23 10.9 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KFP08092.1 - 6.7e-36 123.7 31.0 7.5e-29 100.5 14.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP08092.1 - 3e-07 29.3 21.6 3e-07 29.3 15.0 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter ESSS PF10183.4 KFP08092.1 - 0.4 11.1 2.2 8.9 6.7 0.1 2.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HSP70 PF00012.15 KFP08093.1 - 4.6e-172 573.0 12.2 2.9e-163 544.0 0.3 2.9 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 KFP08093.1 - 4.6e-08 32.0 0.0 7.9e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Ank_2 PF12796.2 KFP08094.1 - 4.7e-147 478.7 48.4 5.9e-20 71.4 0.7 9.3 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KFP08094.1 - 9.2e-129 413.3 48.3 1.5e-08 33.9 0.1 19.6 19 0 0 19 19 19 19 Ankyrin repeat Ank_4 PF13637.1 KFP08094.1 - 9e-103 335.0 28.4 1.4e-10 41.4 0.0 15.1 3 2 12 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP08094.1 - 8.1e-92 291.8 26.3 1.3e-06 28.0 0.0 19.2 20 0 0 20 20 20 17 Ankyrin repeat Ank_5 PF13857.1 KFP08094.1 - 1.1e-86 282.8 43.4 7.6e-10 38.7 0.2 14.5 5 4 9 15 15 15 14 Ankyrin repeats (many copies) AAA_17 PF13207.1 KFP08094.1 - 0.033 15.0 0.1 1.9 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFP08094.1 - 0.034 13.7 0.2 0.15 11.7 0.1 2.1 1 1 0 1 1 1 0 NACHT domain Sprouty PF05210.8 KFP08095.1 - 8.6e-34 115.8 32.7 1.4e-33 115.1 22.6 1.3 1 0 0 1 1 1 1 Sprouty protein (Spry) FAM220 PF15487.1 KFP08095.1 - 0.46 9.8 3.2 0.63 9.3 2.2 1.2 1 0 0 1 1 1 0 FAM220 family AAA PF00004.24 KFP08096.1 - 3.1e-91 302.4 0.0 3.5e-45 153.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFP08096.1 - 5.1e-15 55.1 0.0 6.5e-08 31.9 0.0 3.1 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFP08096.1 - 2.5e-12 46.6 0.1 0.00014 21.5 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFP08096.1 - 5.6e-11 42.7 0.0 5.3e-05 23.2 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 KFP08096.1 - 2e-10 39.9 0.1 0.00011 21.0 0.0 3.1 3 0 0 3 3 3 2 TIP49 C-terminus AAA_2 PF07724.9 KFP08096.1 - 1.3e-09 38.1 0.0 0.00032 20.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KFP08096.1 - 2e-09 37.6 0.1 0.0016 18.6 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFP08096.1 - 3.6e-08 34.2 0.0 0.00045 21.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFP08096.1 - 6.6e-08 32.5 0.0 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFP08096.1 - 7.7e-08 31.9 0.0 0.003 17.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KFP08096.1 - 1.5e-07 31.0 1.5 0.072 12.4 0.0 4.0 2 2 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 KFP08096.1 - 3e-07 29.8 0.7 0.0067 15.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFP08096.1 - 3.3e-07 29.6 0.0 0.0066 15.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KFP08096.1 - 6.8e-07 28.9 1.1 0.0023 17.6 0.3 3.6 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KFP08096.1 - 8.6e-07 29.0 0.0 0.0095 15.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.17 KFP08096.1 - 1.3e-06 28.5 0.0 0.0061 16.7 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 KFP08096.1 - 3.5e-06 26.9 0.0 0.0035 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KFP08096.1 - 5.3e-06 25.4 0.1 0.0038 16.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KFP08096.1 - 6.1e-06 26.2 0.0 0.03 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.13 KFP08096.1 - 7.5e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_3 PF07726.6 KFP08096.1 - 1.3e-05 24.8 0.0 0.27 10.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KFP08096.1 - 0.00019 20.6 0.0 0.093 11.8 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 KFP08096.1 - 0.00023 21.4 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFP08096.1 - 0.00034 20.1 0.0 0.36 10.3 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KFP08096.1 - 0.00035 20.2 0.4 0.12 12.0 0.0 3.3 4 0 0 4 4 3 1 NACHT domain DUF815 PF05673.8 KFP08096.1 - 0.0005 19.0 0.0 0.12 11.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 KFP08096.1 - 0.00067 18.4 0.0 0.082 11.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 KFP08096.1 - 0.001 18.6 0.6 0.15 11.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFP08096.1 - 0.001 19.3 0.0 0.98 9.7 0.0 3.0 2 1 1 3 3 3 1 ABC transporter UPF0079 PF02367.12 KFP08096.1 - 0.0022 17.6 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KFP08096.1 - 0.0033 16.9 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain CDC48_2 PF02933.12 KFP08096.1 - 0.0061 16.1 0.3 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_11 PF13086.1 KFP08096.1 - 0.0064 16.0 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KFP08096.1 - 0.011 14.5 0.1 0.43 9.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.17 KFP08096.1 - 0.019 14.8 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase IPT PF01745.11 KFP08096.1 - 0.034 13.3 0.1 0.76 8.9 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin2 PF13189.1 KFP08096.1 - 0.035 14.0 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Arch_ATPase PF01637.13 KFP08096.1 - 0.038 13.6 0.0 1.1 8.8 0.0 2.6 2 2 1 3 3 3 0 Archaeal ATPase PhoH PF02562.11 KFP08096.1 - 0.043 13.0 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.1 KFP08096.1 - 0.088 13.1 0.0 0.64 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MS_channel PF00924.13 KFP08096.1 - 0.21 10.8 0.1 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel DUF2075 PF09848.4 KFP08096.1 - 0.28 10.0 0.0 0.72 8.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NUDIX PF00293.23 KFP08097.1 - 1.1e-21 76.8 0.0 1.5e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain FGF PF00167.13 KFP08098.1 - 1.3e-27 96.0 0.0 1.4e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor IL1 PF00340.14 KFP08098.1 - 0.0006 19.2 0.3 0.0011 18.4 0.2 1.4 1 1 0 1 1 1 1 Interleukin-1 / 18 Cpn60_TCP1 PF00118.19 KFP08099.1 - 1e-20 73.8 0.3 3.6e-09 35.7 0.0 2.4 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family EF-hand_1 PF00036.27 KFP08100.1 - 9.6e-36 118.3 19.3 3.3e-09 35.3 1.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFP08100.1 - 2.8e-30 104.2 11.3 4.3e-17 61.9 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP08100.1 - 1.2e-27 93.2 12.7 3.2e-09 35.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KFP08100.1 - 3.7e-26 90.5 18.6 2e-12 46.4 0.8 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KFP08100.1 - 3.8e-21 73.4 20.9 2.9e-06 26.3 0.3 4.6 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 KFP08100.1 - 2.3e-15 56.2 0.2 2e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KFP08100.1 - 2.2e-06 27.3 9.4 0.28 10.9 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 KFP08100.1 - 0.002 16.5 0.7 0.75 8.0 0.0 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) SPARC_Ca_bdg PF10591.4 KFP08100.1 - 0.0033 17.4 0.7 1.4 8.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KFP08100.1 - 0.034 13.7 0.1 11 5.7 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) PB1 PF00564.19 KFP08100.1 - 0.037 13.7 0.5 4.9 6.9 0.1 2.6 2 0 0 2 2 2 0 PB1 domain Phg_2220_C PF09524.5 KFP08100.1 - 0.051 13.5 0.7 5 7.2 0.1 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) SRI PF08236.6 KFP08100.1 - 0.056 13.3 1.1 0.34 10.8 0.1 2.4 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DUF3349 PF11829.3 KFP08100.1 - 0.063 13.7 1.2 16 5.9 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3349) DUF4601 PF15373.1 KFP08100.1 - 0.069 11.9 0.2 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) TBPIP PF07106.8 KFP08100.1 - 0.071 12.6 2.5 1.5 8.3 0.3 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF21 PF01595.15 KFP08100.1 - 0.1 11.8 0.9 0.9 8.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 PMBR PF09373.5 KFP08100.1 - 0.14 12.2 0.1 82 3.4 0.0 4.0 4 0 0 4 4 4 0 Pseudomurein-binding repeat TerB PF05099.8 KFP08100.1 - 0.2 11.3 3.0 1.7 8.4 0.1 2.7 1 1 1 3 3 3 0 Tellurite resistance protein TerB EF-hand_10 PF14788.1 KFP08100.1 - 0.34 10.6 3.6 0.94 9.1 0.6 2.7 3 0 0 3 3 3 0 EF hand Toprim_2 PF13155.1 KFP08100.1 - 0.43 10.9 3.2 11 6.4 0.1 2.5 1 1 1 2 2 2 0 Toprim-like Excalibur PF05901.6 KFP08100.1 - 0.77 10.1 2.6 2 8.8 0.1 2.3 2 1 0 2 2 2 0 Excalibur calcium-binding domain BCNT PF07572.7 KFP08100.1 - 2.6 8.0 6.1 9 6.3 0.1 2.8 3 0 0 3 3 3 0 Bucentaur or craniofacial development DUF1542 PF07564.6 KFP08100.1 - 2.7 8.0 5.5 27 4.8 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) IL15 PF02372.10 KFP08101.1 - 4.1e-13 49.2 1.1 5.1e-13 48.9 0.8 1.1 1 0 0 1 1 1 1 Interleukin 15 eRF1_2 PF03464.10 KFP08101.1 - 0.0036 17.6 0.0 0.0051 17.1 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 IL15 PF02372.10 KFP08102.1 - 1e-30 106.3 6.2 7.5e-29 100.2 4.3 2.0 1 1 0 1 1 1 1 Interleukin 15 zf-C3HC PF07967.8 KFP08102.1 - 0.024 14.3 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 C3HC zinc finger-like DUF3615 PF12274.3 KFP08102.1 - 0.067 13.5 0.1 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3615) Spc7 PF08317.6 KFP08102.1 - 0.17 10.5 5.3 0.2 10.2 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Ion_trans PF00520.26 KFP08103.1 - 4.7e-37 127.1 14.5 4.7e-37 127.1 10.1 1.6 2 0 0 2 2 2 1 Ion transport protein TRP_2 PF08344.6 KFP08103.1 - 4.1e-31 106.6 1.5 1e-30 105.4 1.0 1.7 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.2 KFP08103.1 - 1.2e-13 51.1 0.2 9.6e-10 38.6 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PKD_channel PF08016.7 KFP08103.1 - 4.1e-12 45.2 16.5 2.3e-11 42.7 11.4 2.0 1 1 0 1 1 1 1 Polycystin cation channel Ank_4 PF13637.1 KFP08103.1 - 2.5e-11 43.7 0.0 3.7e-07 30.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KFP08103.1 - 9.3e-09 34.6 0.9 0.019 14.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KFP08103.1 - 9.8e-09 35.1 0.2 0.098 12.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP08103.1 - 8.9e-08 31.6 1.1 0.84 10.0 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat PBC PF03792.8 KFP08103.1 - 0.04 13.5 0.2 0.24 11.0 0.0 2.1 1 1 1 2 2 2 0 PBC domain BBS2_Mid PF14783.1 KFP08104.1 - 0.00088 19.0 0.0 0.0036 17.0 0.0 2.1 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Mcm10 PF09332.6 KFP08104.1 - 0.16 11.2 1.1 0.25 10.6 0.7 1.2 1 0 0 1 1 1 0 Mcm10 replication factor GAS PF13851.1 KFP08104.1 - 0.35 10.0 8.1 0.21 10.7 1.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cyclin_N PF00134.18 KFP08105.1 - 8.7e-50 167.5 0.3 1.6e-49 166.7 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP08105.1 - 2.1e-29 101.8 0.4 1.1e-28 99.5 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain RNase_PH PF01138.16 KFP08106.1 - 8.3e-16 58.5 0.0 1.6e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFP08106.1 - 6e-11 42.1 0.1 1.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Annexin PF00191.15 KFP08107.1 - 1.4e-97 319.5 9.1 2.5e-24 84.9 0.1 4.0 4 0 0 4 4 4 4 Annexin HTH_AraC PF00165.18 KFP08107.1 - 0.086 12.7 0.0 0.35 10.7 0.0 2.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Peptidase_C14 PF00656.17 KFP08107.1 - 0.094 12.3 0.2 1.6 8.3 0.0 2.5 3 0 0 3 3 3 0 Caspase domain DUF2968 PF11180.3 KFP08108.1 - 0.0055 16.1 4.8 0.0083 15.5 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF4047 PF13256.1 KFP08108.1 - 0.006 16.5 1.2 0.012 15.5 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4047) XhlA PF10779.4 KFP08108.1 - 0.053 13.4 1.1 0.053 13.4 0.8 1.9 2 0 0 2 2 2 0 Haemolysin XhlA Spc7 PF08317.6 KFP08108.1 - 0.19 10.3 10.5 0.51 8.9 7.5 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein PEP-utilisers_N PF05524.8 KFP08108.1 - 0.38 10.5 2.8 0.35 10.6 0.3 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal CDC37_N PF03234.9 KFP08108.1 - 0.8 10.0 8.4 1.2 9.3 5.8 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4140 PF13600.1 KFP08108.1 - 1.1 9.7 7.1 1.1 9.6 2.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 KFP08108.1 - 1.2 8.7 12.0 0.14 11.7 4.9 1.9 1 1 1 2 2 2 0 Mnd1 family DUF2353 PF09789.4 KFP08108.1 - 1.3 8.1 13.0 1.7 7.8 9.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) FlxA PF14282.1 KFP08108.1 - 1.5 8.7 8.1 1.4 8.9 4.7 1.6 1 1 0 1 1 1 0 FlxA-like protein DUF2369 PF10179.4 KFP08109.1 - 1.9e-103 345.7 8.6 1.1e-94 316.8 4.5 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) fn3 PF00041.16 KFP08109.1 - 2e-09 37.4 0.5 0.0031 17.6 0.0 3.9 3 0 0 3 3 3 3 Fibronectin type III domain zf-H2C2_2 PF13465.1 KFP08110.1 - 2.7e-80 260.9 116.8 1.7e-10 40.6 0.4 16.8 17 0 0 17 17 17 15 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08110.1 - 5.5e-68 221.3 115.5 2.4e-06 27.5 0.4 16.2 16 0 0 16 16 16 16 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08110.1 - 5.9e-56 182.7 101.8 0.00041 20.4 0.2 16.2 16 0 0 16 16 16 16 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP08110.1 - 4.9e-37 125.2 95.8 5.8e-06 26.2 0.7 16.2 16 0 0 16 16 16 12 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP08110.1 - 8.4e-29 98.8 93.2 0.00017 21.6 1.3 15.7 16 0 0 16 16 16 9 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP08110.1 - 5e-24 83.4 86.0 0.0012 18.7 0.6 16.6 16 0 0 16 16 16 13 C2H2-type zinc finger zf-Di19 PF05605.7 KFP08110.1 - 1.2e-10 41.2 79.9 0.0022 18.1 2.6 9.9 6 2 2 9 9 9 6 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFP08110.1 - 0.0013 18.8 91.2 0.41 10.7 0.5 13.4 1 1 10 13 13 12 5 C2H2 type zinc-finger (2 copies) Trm112p PF03966.11 KFP08110.1 - 0.0069 16.7 15.3 0.12 12.7 0.7 5.5 3 3 1 4 4 4 1 Trm112p-like protein zf-RING_3 PF14369.1 KFP08110.1 - 0.01 15.8 42.9 3.6 7.6 0.0 11.3 12 1 0 12 12 12 0 zinc-finger zf-H2C2_5 PF13909.1 KFP08110.1 - 0.012 15.8 4.7 0.079 13.2 0.3 15.4 16 1 0 16 16 16 0 C2H2-type zinc-finger domain zf-CHCC PF10276.4 KFP08110.1 - 0.11 12.3 0.3 0.11 12.3 0.2 9.2 12 0 0 12 12 11 0 Zinc-finger domain zf-CHY PF05495.7 KFP08110.1 - 0.55 10.4 87.2 0.15 12.2 3.5 8.2 2 2 7 9 9 8 0 CHY zinc finger zf-C2HC_2 PF13913.1 KFP08110.1 - 0.77 9.4 63.2 0.18 11.5 1.7 12.8 14 0 0 14 14 13 0 zinc-finger of a C2HC-type SET PF00856.23 KFP08110.1 - 0.89 9.8 5.7 6.3 7.0 3.7 2.9 1 1 0 1 1 1 0 SET domain BolA PF01722.13 KFP08110.1 - 3.8 7.5 16.0 11 6.0 0.0 6.0 5 2 1 6 6 5 0 BolA-like protein PLA2_B PF01735.13 KFP08111.1 - 1.2e-151 505.2 0.0 1.4e-150 501.7 0.0 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain C2 PF00168.25 KFP08111.1 - 1.6e-14 53.4 0.1 3.8e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain An_peroxidase PF03098.10 KFP08112.1 - 1.1e-98 330.9 0.0 4.1e-96 322.4 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase EGF PF00008.22 KFP08112.1 - 0.00083 19.2 12.5 0.0017 18.2 8.7 1.6 1 0 0 1 1 1 1 EGF-like domain Phosducin PF02114.11 KFP08113.1 - 4.3e-113 376.4 1.1 5.1e-113 376.1 0.8 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KFP08113.1 - 0.0019 17.8 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ODR4-like PF14778.1 KFP08114.1 - 1.2e-107 359.7 0.2 1.5e-107 359.4 0.1 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like TPR_MLP1_2 PF07926.7 KFP08115.1 - 2.6e-30 104.8 30.1 2.6e-30 104.8 20.9 14.5 5 4 5 12 12 12 6 TPR/MLP1/MLP2-like protein TilS PF09179.6 KFP08115.1 - 5.9 6.9 13.5 0.17 11.9 0.1 4.9 5 0 0 5 5 5 0 TilS substrate binding domain Somatomedin_B PF01033.12 KFP08116.1 - 1.6e-21 75.9 47.1 4.6e-12 45.7 12.8 3.0 2 1 1 3 3 3 2 Somatomedin B domain Hemopexin PF00045.14 KFP08116.1 - 1.3e-15 56.8 5.2 1.3e-11 43.9 0.0 3.8 5 0 0 5 5 5 2 Hemopexin RGS PF00615.14 KFP08117.1 - 5.4e-40 136.1 7.6 6.2e-40 135.9 5.3 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C12 PF01088.16 KFP08118.1 - 2.4e-62 209.9 1.2 2.4e-62 209.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TROVE PF05731.6 KFP08119.1 - 5.3e-108 361.1 0.2 6.7e-108 360.8 0.1 1.1 1 0 0 1 1 1 1 TROVE domain DUF2201 PF09967.4 KFP08119.1 - 9.9e-07 28.8 0.4 2.2e-06 27.7 0.3 1.5 1 0 0 1 1 1 1 VWA-like domain (DUF2201) VWA_2 PF13519.1 KFP08119.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFP08119.1 - 0.2 10.7 0.9 0.53 9.3 0.6 1.7 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Glutaredoxin PF00462.19 KFP08120.1 - 5.3e-21 74.3 0.0 6.3e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KFP08120.1 - 0.00024 20.8 0.0 0.0003 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 KFP08120.1 - 0.0014 18.8 0.5 0.0019 18.3 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 KFP08120.1 - 0.0059 16.2 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 KFP08120.1 - 0.0077 16.4 0.0 0.011 15.9 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) ArsC PF03960.10 KFP08120.1 - 0.011 15.8 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 ArsC family DSBA PF01323.15 KFP08120.1 - 0.014 14.9 0.2 0.85 9.1 0.0 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain DUF2117 PF09890.4 KFP08120.1 - 0.022 13.9 0.0 0.026 13.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) Thioredoxin_9 PF14595.1 KFP08120.1 - 0.053 13.0 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 KFP08120.1 - 0.061 13.3 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like CDC73 PF05179.9 KFP08121.1 - 3.1e-115 384.2 0.8 4.3e-115 383.7 0.0 1.6 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family Galactosyl_T PF01762.16 KFP08122.1 - 6.9e-66 221.5 0.0 9.8e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase BK_channel_a PF03493.13 KFP08123.1 - 1.8e-36 124.1 0.3 6.3e-36 122.3 0.2 2.0 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 KFP08123.1 - 3.6e-12 45.8 4.8 8.7e-12 44.5 2.9 2.0 2 0 0 2 2 2 1 Ion channel Phi-29_GP4 PF05464.6 KFP08123.1 - 0.15 11.9 1.2 1.2 9.0 0.4 2.6 3 0 0 3 3 3 0 Phi-29-like late genes activator (early protein GP4) Sushi PF00084.15 KFP08124.1 - 9.3e-150 487.0 151.4 1.7e-11 44.2 0.3 19.5 19 1 1 20 20 20 18 Sushi domain (SCR repeat) Sushi PF00084.15 KFP08125.1 - 1.5e-53 178.9 61.2 1.1e-09 38.5 1.5 9.3 9 0 0 9 9 9 9 Sushi domain (SCR repeat) Sushi_2 PF09014.5 KFP08125.1 - 0.0045 16.7 26.6 0.018 14.7 0.2 7.0 6 2 2 8 8 8 2 Beta-2-glycoprotein-1 fifth domain Ribosomal_L21e PF01157.13 KFP08125.1 - 0.16 11.7 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L21e zf-H2C2_2 PF13465.1 KFP08126.1 - 4.4e-53 175.0 129.5 4.5e-07 29.8 0.6 15.3 16 0 0 16 16 15 13 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08126.1 - 2.7e-43 143.7 142.3 6.1e-05 23.1 2.3 15.0 14 1 0 14 14 14 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08126.1 - 3.4e-33 111.5 128.9 0.00096 19.3 0.6 15.1 15 0 0 15 15 15 13 C2H2-type zinc finger BTB PF00651.26 KFP08126.1 - 3.3e-21 75.3 0.7 8.4e-21 74.0 0.5 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_6 PF13912.1 KFP08126.1 - 1.8e-08 34.0 102.2 0.00052 19.8 0.7 13.7 14 0 0 14 14 14 8 C2H2-type zinc finger zf-met PF12874.2 KFP08126.1 - 3.9e-08 33.2 90.5 0.00035 20.6 1.0 13.4 14 0 0 14 14 13 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP08126.1 - 2.3e-06 27.5 90.3 0.039 14.1 1.7 13.6 14 0 0 14 14 13 7 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 KFP08126.1 - 0.045 13.3 16.1 4.1 7.0 0.1 6.4 3 2 3 6 6 6 0 GAGA factor zf-C2H2_2 PF12756.2 KFP08126.1 - 0.066 13.3 84.5 0.079 13.0 0.1 13.2 3 1 7 11 11 10 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KFP08126.1 - 0.076 12.6 0.2 0.076 12.6 0.2 12.1 14 0 0 14 14 14 0 zinc-finger of a C2HC-type Thioredoxin_2 PF13098.1 KFP08126.1 - 0.65 10.2 5.2 1.2 9.3 1.5 2.9 2 0 0 2 2 2 0 Thioredoxin-like domain EGF PF00008.22 KFP08127.1 - 1e-94 309.7 272.9 9.7e-08 31.8 5.5 19.8 19 1 0 19 19 19 17 EGF-like domain Laminin_G_2 PF02210.19 KFP08127.1 - 3.5e-51 172.5 2.3 2.6e-18 66.2 0.0 3.4 3 0 0 3 3 3 3 Laminin G domain Laminin_G_1 PF00054.18 KFP08127.1 - 9.7e-39 132.3 0.3 1.1e-14 54.5 0.0 3.6 3 0 0 3 3 3 3 Laminin G domain hEGF PF12661.2 KFP08127.1 - 4.8e-18 63.9 173.6 0.0022 17.9 1.6 17.5 17 0 0 17 17 17 11 Human growth factor-like EGF EGF_CA PF07645.10 KFP08127.1 - 6.2e-18 64.5 262.3 1.4e-05 25.0 3.9 19.8 14 4 6 20 20 20 13 Calcium-binding EGF domain EGF_2 PF07974.8 KFP08127.1 - 7.6e-14 51.5 303.1 0.0016 18.5 6.1 18.8 19 0 0 19 19 19 15 EGF-like domain Laminin_G_3 PF13385.1 KFP08127.1 - 8.4e-06 26.0 0.0 0.11 12.7 0.0 3.1 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily DENN PF02141.16 KFP08128.1 - 4.8e-49 166.5 3.2 8.4e-49 165.7 2.2 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KFP08128.1 - 1.8e-18 66.3 0.0 6.7e-18 64.5 0.0 2.1 2 0 0 2 2 2 1 dDENN domain DUF4407 PF14362.1 KFP08128.1 - 0.086 11.7 1.9 0.14 11.1 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPA PF08616.5 KFP08128.1 - 0.099 12.3 0.2 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis Pkinase PF00069.20 KFP08129.1 - 3.2e-67 226.4 0.0 3.9e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08129.1 - 2.3e-48 164.5 0.0 2.8e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP08129.1 - 2.5e-08 33.2 0.0 3.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.3 KFP08129.1 - 0.0093 15.4 0.2 0.43 9.9 0.1 2.2 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Kdo PF06293.9 KFP08129.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RMMBL PF07521.7 KFP08129.1 - 0.019 14.7 0.1 0.88 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase V-ATPase_G PF03179.10 KFP08130.1 - 2.2e-33 114.6 13.3 2.5e-33 114.5 9.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit CKAP2_C PF15297.1 KFP08130.1 - 0.015 14.0 6.7 0.017 13.9 4.6 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus 7TMR-HDED PF07697.6 KFP08130.1 - 0.038 13.7 5.1 0.053 13.2 3.6 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DUF2072 PF09845.4 KFP08130.1 - 0.053 13.4 4.2 0.067 13.1 2.9 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Baculo_p24 PF05073.7 KFP08130.1 - 0.058 12.9 2.8 0.078 12.5 1.9 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein FdhE PF04216.7 KFP08130.1 - 0.069 12.8 1.4 0.08 12.6 1.0 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF2392 PF10288.4 KFP08130.1 - 0.097 13.0 2.1 0.13 12.5 1.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) HrpE PF06188.7 KFP08130.1 - 0.17 11.5 5.2 0.23 11.1 3.6 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E GA PF01468.12 KFP08130.1 - 0.19 11.9 8.2 0.12 12.5 2.5 2.7 2 1 1 3 3 3 0 GA module AIP3 PF03915.8 KFP08130.1 - 0.22 10.3 9.3 0.25 10.1 6.4 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 LPP20 PF02169.11 KFP08130.1 - 0.27 11.3 3.7 0.33 11.0 2.6 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein DUF3552 PF12072.3 KFP08130.1 - 0.55 9.4 16.7 0.88 8.7 11.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Cor1 PF04803.7 KFP08130.1 - 0.57 9.9 11.8 16 5.2 8.2 2.3 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Exonuc_VII_L PF02601.10 KFP08130.1 - 0.64 9.1 8.8 0.78 8.8 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.8 KFP08130.1 - 1.2 9.5 8.0 2.5 8.5 3.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1542 PF07564.6 KFP08130.1 - 1.3 9.1 7.7 1.1 9.3 3.4 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) RabGAP-TBC PF00566.13 KFP08130.1 - 1.5 8.2 4.3 2.6 7.4 3.0 1.5 1 1 0 1 1 1 0 Rab-GTPase-TBC domain Lipoprotein_3 PF00938.12 KFP08130.1 - 3.7 7.3 6.8 0.37 10.5 1.1 1.9 2 0 0 2 2 2 0 Lipoprotein DUF342 PF03961.8 KFP08130.1 - 4 5.7 9.4 4.6 5.5 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 KFP08130.1 - 4.3 6.9 11.9 5.3 6.6 8.2 1.1 1 0 0 1 1 1 0 Mnd1 family ATP-synt_B PF00430.13 KFP08130.1 - 5.4 6.8 14.9 2.9 7.7 7.8 1.7 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Muted PF14942.1 KFP08130.1 - 7.4 6.4 13.8 4.6 7.0 5.9 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Y_phosphatase PF00102.22 KFP08131.1 - 5.3e-161 533.2 9.8 3.8e-84 281.7 0.0 2.9 4 0 0 4 4 4 2 Protein-tyrosine phosphatase fn3 PF00041.16 KFP08131.1 - 1.5e-07 31.3 8.1 0.00019 21.4 0.1 4.9 5 1 0 5 5 5 2 Fibronectin type III domain Y_phosphatase3 PF13350.1 KFP08131.1 - 1.6e-06 28.4 0.7 0.093 12.9 0.0 3.2 3 0 0 3 3 3 2 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFP08131.1 - 1.7e-06 28.1 0.2 0.24 11.4 0.1 4.1 4 0 0 4 4 4 2 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 KFP08131.1 - 0.0041 16.5 0.0 3.7 6.9 0.0 2.7 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.15 KFP08131.1 - 0.0049 16.4 0.0 0.071 12.6 0.0 2.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Hormone_recep PF00104.25 KFP08132.1 - 1.1e-32 112.8 4.7 1.7e-32 112.2 3.3 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP08132.1 - 2.4e-32 110.9 12.0 3.9e-32 110.2 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-H2C2_2 PF13465.1 KFP08133.1 - 2.2e-21 75.0 20.5 2.1e-06 27.7 0.1 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08133.1 - 4.4e-12 45.5 36.2 0.0038 17.4 0.7 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08133.1 - 5.5e-08 32.6 29.7 0.014 15.6 3.1 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger RRN7 PF11781.3 KFP08133.1 - 0.42 10.1 3.1 31 4.1 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1595 PF12760.2 KFP08133.1 - 0.96 9.3 13.3 0.14 11.9 1.6 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.6 KFP08133.1 - 1.4 8.5 9.7 0.15 11.7 1.3 2.9 1 1 1 3 3 3 0 GAGA factor zf-C2H2_6 PF13912.1 KFP08133.1 - 8.3 6.4 24.3 0.16 11.9 0.9 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger Kinesin PF00225.18 KFP08134.1 - 7.4e-109 363.4 0.3 7.4e-109 363.4 0.2 2.2 2 0 0 2 2 2 1 Kinesin motor domain FHA PF00498.21 KFP08134.1 - 1e-08 35.1 0.1 2.4e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain DEAD PF00270.24 KFP08135.1 - 3.8e-42 143.6 1.0 3.8e-42 143.6 0.7 2.1 2 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFP08135.1 - 2.9e-20 71.8 0.1 8.4e-20 70.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-HIT PF04438.11 KFP08135.1 - 2.3e-08 33.5 1.9 3.8e-08 32.8 1.3 1.4 1 0 0 1 1 1 1 HIT zinc finger SecA_DEAD PF07517.9 KFP08135.1 - 0.0055 16.0 0.9 0.32 10.2 0.0 2.5 3 0 0 3 3 3 1 SecA DEAD-like domain ResIII PF04851.10 KFP08135.1 - 0.013 15.3 0.1 0.079 12.7 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.24 KFP08135.1 - 0.051 13.7 1.0 0.15 12.2 0.3 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CAMSAP_CKK PF08683.6 KFP08137.1 - 2.6e-47 159.5 0.1 5.9e-47 158.4 0.1 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH PF00307.26 KFP08137.1 - 9.5e-37 125.3 2.2 3.5e-36 123.5 0.8 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP08137.1 - 7.6e-35 118.4 1.5 2.5e-34 116.7 1.1 1.9 1 0 0 1 1 1 1 CAMSAP CH domain WD40 PF00400.27 KFP08138.1 - 5.3e-42 140.2 12.8 1.1e-08 34.5 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat MCLC PF05934.6 KFP08139.1 - 2.4e-164 547.6 10.4 5.6e-164 546.4 7.2 1.5 1 1 0 1 1 1 1 Mid-1-related chloride channel (MCLC) PAP2 PF01569.16 KFP08139.1 - 0.81 9.3 5.9 0.21 11.2 1.6 1.8 2 0 0 2 2 2 0 PAP2 superfamily SPC25 PF06703.6 KFP08139.1 - 2.3 7.8 7.9 2.5 7.6 3.3 2.4 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) TPR_12 PF13424.1 KFP08140.1 - 1.1e-39 134.1 31.2 3.9e-11 42.7 4.5 5.7 3 2 4 7 7 7 7 Tetratricopeptide repeat GoLoco PF02188.12 KFP08140.1 - 2.4e-38 128.6 30.4 2.9e-10 39.1 0.4 4.5 4 0 0 4 4 4 4 GoLoco motif TPR_1 PF00515.23 KFP08140.1 - 2.4e-36 121.8 31.3 6.1e-07 28.7 0.4 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFP08140.1 - 1.4e-29 99.4 21.0 1.9e-05 24.1 0.2 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFP08140.1 - 1.7e-22 78.8 24.2 7.2e-08 31.9 0.8 5.2 4 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 KFP08140.1 - 1.1e-21 74.9 30.2 5.3e-05 22.8 0.9 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 KFP08140.1 - 1.7e-16 59.5 24.3 0.016 15.1 0.9 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFP08140.1 - 3.1e-16 57.8 23.5 0.00015 21.2 0.2 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFP08140.1 - 8.3e-09 35.3 7.1 0.03 14.9 0.3 6.9 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFP08140.1 - 9.2e-09 34.9 0.1 0.64 10.6 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFP08140.1 - 1.1e-06 29.1 20.7 0.0024 18.5 1.6 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFP08140.1 - 1.6e-05 24.7 19.9 3.5 8.0 0.1 7.9 7 1 1 8 8 7 3 Tetratricopeptide repeat Rapsyn_N PF10579.4 KFP08140.1 - 2.4e-05 24.0 5.0 1.8 8.4 0.1 5.7 3 2 4 7 7 7 1 Rapsyn N-terminal myristoylation and linker region Apc3 PF12895.2 KFP08140.1 - 0.00023 21.2 14.5 0.12 12.5 3.0 5.2 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFP08140.1 - 0.0021 18.4 9.0 1.8 9.1 0.4 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat UreE_C PF05194.7 KFP08140.1 - 7.3 6.7 8.4 16 5.6 0.2 3.7 4 1 1 5 5 4 0 UreE urease accessory protein, C-terminal domain Sec1 PF00995.18 KFP08141.1 - 1.4e-138 462.9 1.9 1.6e-138 462.8 1.3 1.0 1 0 0 1 1 1 1 Sec1 family DUF2621 PF11084.3 KFP08141.1 - 0.019 14.6 0.3 0.05 13.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) PRP38 PF03371.10 KFP08142.1 - 4.6e-57 192.4 0.0 6e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Methyltransf_23 PF13489.1 KFP08143.1 - 9.4e-06 25.4 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP08143.1 - 0.021 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NT-C2 PF10358.4 KFP08144.1 - 4e-11 42.5 0.0 7.5e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins FRG2 PF15315.1 KFP08144.1 - 0.35 10.8 5.3 0.55 10.1 3.7 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Mito_carr PF00153.22 KFP08145.1 - 2.7e-75 248.1 5.7 2.3e-26 91.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KFP08145.1 - 1.7e-21 76.0 4.1 1.2e-11 44.5 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP08145.1 - 4e-21 72.6 7.5 3.1e-06 26.0 0.4 4.8 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KFP08145.1 - 2.1e-19 67.6 6.1 0.0003 20.4 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFP08145.1 - 1.4e-16 58.9 14.5 2.2e-05 23.5 0.1 5.1 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFP08145.1 - 1.3e-13 50.3 4.4 2.1e-09 36.8 0.3 4.2 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP08145.1 - 6.7e-08 32.5 0.1 0.0096 15.9 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KFP08145.1 - 1.3e-06 27.9 0.3 0.003 17.1 0.0 3.6 2 2 2 4 4 4 2 EF hand EF-hand_4 PF12763.2 KFP08145.1 - 0.00017 21.2 2.4 0.0049 16.5 0.0 2.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFP08145.1 - 0.00049 19.9 0.0 1.3 8.9 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain DUF2340 PF10209.4 KFP08145.1 - 0.03 14.4 0.1 0.19 11.8 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) Sigma_reg_C PF13791.1 KFP08145.1 - 0.044 13.8 0.7 0.078 13.0 0.5 1.3 1 0 0 1 1 1 0 Sigma factor regulator C-terminal TerB PF05099.8 KFP08145.1 - 0.048 13.3 0.1 0.63 9.7 0.0 2.3 2 0 0 2 2 2 0 Tellurite resistance protein TerB Dockerin_1 PF00404.13 KFP08145.1 - 0.25 11.1 6.7 4.3 7.2 0.1 4.2 4 0 0 4 4 4 0 Dockerin type I repeat RhoGEF PF00621.15 KFP08146.1 - 3.7e-40 137.7 8.2 8.3e-40 136.5 5.7 1.6 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.12 KFP08146.1 - 6.9e-27 92.6 0.0 1.8e-14 52.9 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 KFP08146.1 - 5.3e-19 67.5 0.1 4.3e-12 45.4 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFP08146.1 - 6.6e-17 60.6 0.1 5.6e-13 48.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH2 PF00017.19 KFP08146.1 - 1.7e-15 56.5 0.5 7.2e-15 54.5 0.4 2.1 1 0 0 1 1 1 1 SH2 domain C1_1 PF00130.17 KFP08146.1 - 1e-09 37.9 4.7 1.9e-09 37.0 3.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.24 KFP08146.1 - 2.3e-07 30.9 0.1 5.2e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 PH domain Filamin PF00630.14 KFP08146.1 - 0.0008 19.9 0.0 0.0067 16.9 0.0 2.2 2 0 0 2 2 2 1 Filamin/ABP280 repeat Prok-RING_1 PF14446.1 KFP08146.1 - 0.018 14.7 1.8 0.042 13.5 1.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 KFP08146.1 - 0.027 14.5 2.3 0.089 12.9 1.6 2.0 1 0 0 1 1 1 0 C1 domain DUF2247 PF10004.4 KFP08146.1 - 1.2 8.8 6.2 0.23 11.1 0.1 2.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) Laminin_N PF00055.12 KFP08147.1 - 4.7e-31 107.6 0.7 4.7e-31 107.6 0.5 2.4 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.19 KFP08147.1 - 9.4e-23 79.8 61.8 1.8e-08 34.1 8.0 4.8 3 1 1 4 4 4 3 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 KFP08147.1 - 0.002 18.2 9.3 0.002 18.2 6.4 7.4 6 2 2 8 8 8 1 EGF-like domain EGF PF00008.22 KFP08147.1 - 0.013 15.4 9.1 0.013 15.4 6.3 6.0 6 2 0 6 6 6 0 EGF-like domain hEGF PF12661.2 KFP08147.1 - 0.049 13.7 1.2 0.049 13.7 0.8 6.3 7 0 0 7 7 7 0 Human growth factor-like EGF SF3b10 PF07189.6 KFP08148.1 - 4.5e-40 135.3 0.0 5.2e-40 135.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.4 KFP08148.1 - 0.01 14.5 0.3 0.011 14.3 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) SNARE PF05739.14 KFP08149.1 - 1.2e-14 53.7 1.0 1.2e-14 53.7 0.7 2.7 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFP08149.1 - 1.7e-06 28.1 2.9 1.7e-06 28.1 2.0 2.6 2 1 0 2 2 2 1 Syntaxin Leu_zip PF15294.1 KFP08149.1 - 0.0041 16.2 2.3 0.0041 16.2 1.6 2.1 2 1 0 2 2 2 1 Leucine zipper Toprim_Crpt PF13342.1 KFP08149.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Spectrin PF00435.16 KFP08149.1 - 0.034 14.4 6.4 0.094 13.0 0.8 2.7 2 0 0 2 2 2 0 Spectrin repeat MCPsignal PF00015.16 KFP08149.1 - 0.034 13.6 1.2 0.2 11.1 0.1 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DivIC PF04977.10 KFP08149.1 - 0.063 12.7 0.6 0.063 12.7 0.4 2.8 3 0 0 3 3 3 0 Septum formation initiator FUSC PF04632.7 KFP08149.1 - 0.27 9.6 0.5 0.33 9.3 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.8 KFP08149.1 - 0.59 9.1 3.8 0.38 9.7 0.3 2.0 1 1 0 2 2 2 0 TMPIT-like protein KxDL PF10241.4 KFP08149.1 - 0.93 9.4 6.1 0.2 11.6 0.5 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein FlaC_arch PF05377.6 KFP08149.1 - 1.1 9.2 5.7 1 9.2 0.2 3.3 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) HisKA_3 PF07730.8 KFP08149.1 - 1.9 8.8 6.6 1.5 9.1 0.4 3.3 3 2 2 5 5 4 0 Histidine kinase Prefoldin PF02996.12 KFP08149.1 - 2.9 7.5 8.2 0.31 10.6 0.2 3.1 3 1 0 3 3 3 0 Prefoldin subunit Occludin_ELL PF07303.8 KFP08149.1 - 10 6.9 9.7 0.44 11.3 0.9 2.7 3 1 0 3 3 3 0 Occludin homology domain Spectrin PF00435.16 KFP08150.1 - 1.2e-37 128.3 79.3 2.7e-13 50.1 9.8 7.5 7 0 0 7 7 7 7 Spectrin repeat CH PF00307.26 KFP08150.1 - 3.3e-35 120.4 2.4 6.3e-18 64.8 0.0 4.1 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KFP08150.1 - 3.3e-07 29.8 1.5 0.00043 19.8 0.0 3.8 4 0 0 4 4 4 2 CAMSAP CH domain Spectrin PF00435.16 KFP08151.1 - 6.3e-17 61.7 18.6 7.7e-11 42.2 3.6 3.0 2 1 1 3 3 3 2 Spectrin repeat NPV_P10 PF05531.7 KFP08151.1 - 0.013 15.7 13.6 0.28 11.4 0.4 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4398 PF14346.1 KFP08151.1 - 0.015 15.3 2.3 0.04 13.9 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF948 PF06103.6 KFP08151.1 - 0.025 14.4 6.3 3.7 7.4 0.3 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1995 PF09353.5 KFP08151.1 - 0.042 13.4 0.4 7.1 6.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1995) DUF3702 PF12486.3 KFP08151.1 - 0.1 12.2 7.6 0.82 9.3 2.0 3.0 2 1 0 2 2 2 0 ImpA domain protein EFhand_Ca_insen PF08726.5 KFP08151.1 - 0.11 12.4 1.1 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand AAA_13 PF13166.1 KFP08151.1 - 0.31 9.4 8.5 0.97 7.8 2.0 2.1 1 1 0 1 1 1 0 AAA domain Hrs_helical PF12210.3 KFP08151.1 - 0.43 10.8 0.1 0.43 10.8 0.1 2.8 3 1 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate RmuC PF02646.11 KFP08151.1 - 2.7 6.7 12.5 0.18 10.6 1.1 3.0 3 0 0 3 3 3 0 RmuC family Occludin_ELL PF07303.8 KFP08151.1 - 3.2 8.5 13.2 41 4.9 0.5 3.6 3 1 0 3 3 3 0 Occludin homology domain DSPc PF00782.15 KFP08152.1 - 1.1e-13 50.9 0.0 1.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 KFP08152.1 - 0.00084 18.7 0.0 0.0021 17.4 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family AlaDh_PNT_N PF05222.10 KFP08152.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain PTPlike_phytase PF14566.1 KFP08152.1 - 0.095 12.7 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.7 KFP08152.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 KFP08152.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase F-box PF00646.28 KFP08153.1 - 2.1e-07 30.3 1.1 6.3e-07 28.9 0.7 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFP08153.1 - 9.7e-07 28.4 0.2 2.8e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like zf-TRAF PF02176.13 KFP08153.1 - 0.017 15.4 3.3 0.017 15.4 2.3 5.0 5 1 1 6 6 6 0 TRAF-type zinc finger BH4 PF02180.12 KFP08154.1 - 1.7 8.2 9.6 35 4.0 0.1 4.2 2 1 3 5 5 5 0 Bcl-2 homology region 4 SIC PF03482.8 KFP08154.1 - 5.2 6.6 6.6 10 5.6 4.6 1.6 1 1 0 1 1 1 0 sic protein ANF_receptor PF01094.23 KFP08155.1 - 7.4e-89 297.9 0.0 1.1e-88 297.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFP08155.1 - 5.7e-71 238.6 27.4 8.2e-71 238.1 19.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR GluR_Homer-bdg PF10606.4 KFP08155.1 - 5.2e-27 93.4 8.7 2e-26 91.6 6.0 2.1 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor NCD3G PF07562.9 KFP08155.1 - 4.3e-17 61.5 11.0 1.1e-16 60.2 7.6 1.7 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Ras PF00071.17 KFP08156.1 - 6.4e-39 132.9 0.0 7.1e-39 132.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP08156.1 - 7e-19 68.4 0.0 8.6e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP08156.1 - 2.4e-09 36.6 0.0 2.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP08156.1 - 4.1e-07 29.3 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFP08156.1 - 0.00065 19.6 0.0 0.00082 19.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFP08156.1 - 0.00078 19.5 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KFP08156.1 - 0.0009 18.9 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 KFP08156.1 - 0.0029 17.0 0.0 0.12 11.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KFP08156.1 - 0.0032 17.0 0.0 0.81 9.1 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KFP08156.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KFP08156.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF815 PF05673.8 KFP08156.1 - 0.064 12.1 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KFP08156.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KFP08156.1 - 0.099 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 KFP08156.1 - 0.1 12.0 0.0 0.68 9.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 KFP08156.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 KFP08156.1 - 0.11 12.0 0.1 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFP08156.1 - 0.15 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Globin PF00042.17 KFP08158.1 - 7.7e-08 32.6 0.1 1.5e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Globin IQ PF00612.22 KFP08158.1 - 0.0025 17.3 0.2 0.0065 16.0 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif TAFA PF12020.3 KFP08158.1 - 0.016 15.2 0.2 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 TAFA family Yae1_N PF09811.4 KFP08159.1 - 4.3e-13 48.5 33.2 6.7 6.3 23.0 3.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal LLGL PF08366.8 KFP08160.1 - 1e-43 147.5 0.0 2e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 LLGL2 WD40 PF00400.27 KFP08160.1 - 3.4e-13 48.9 7.4 0.00013 21.6 0.5 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Lgl_C PF08596.5 KFP08160.1 - 1.8e-07 29.9 0.0 7.8e-06 24.6 0.0 3.2 4 0 0 4 4 4 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.16 KFP08160.1 - 0.0027 17.2 0.0 0.0071 15.9 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF3312 PF11768.3 KFP08160.1 - 0.0063 14.7 0.0 0.022 12.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Apc4_WD40 PF12894.2 KFP08160.1 - 0.012 15.1 0.1 0.094 12.2 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ACTH_domain PF00976.13 KFP08160.1 - 0.047 13.5 0.5 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Corticotropin ACTH domain SAM_1 PF00536.25 KFP08161.1 - 6.3e-14 51.8 0.0 8.3e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP08161.1 - 6.2e-11 41.9 0.0 1.2e-10 41.0 0.0 1.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pap_E4 PF02711.9 KFP08161.1 - 0.13 13.0 2.6 0.26 12.1 1.8 1.5 1 0 0 1 1 1 0 E4 protein Mito_fiss_reg PF05308.6 KFP08161.1 - 1.4 8.2 3.4 1.6 7.9 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator RhoGEF PF00621.15 KFP08162.1 - 4e-39 134.3 1.8 4e-39 134.3 1.3 2.3 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 KFP08162.1 - 3.4e-38 129.2 0.1 5.9e-21 73.9 0.0 3.0 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ PF00595.19 KFP08162.1 - 2.4e-10 40.4 0.1 6.7e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PH PF00169.24 KFP08162.1 - 7e-06 26.1 1.3 2.2e-05 24.6 0.1 2.6 2 0 0 2 2 2 1 PH domain PDZ_2 PF13180.1 KFP08162.1 - 0.00023 20.9 0.0 0.45 10.4 0.0 2.8 2 0 0 2 2 2 2 PDZ domain NPV_P10 PF05531.7 KFP08162.1 - 0.85 9.9 2.6 11 6.3 0.0 3.8 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Sulfatase PF00884.18 KFP08165.1 - 5.9e-53 180.0 0.5 1.2e-52 178.9 0.3 1.6 1 0 0 1 1 1 1 Sulfatase DUF3740 PF12548.3 KFP08165.1 - 2.8e-51 173.6 3.8 2.8e-51 173.6 2.6 2.3 2 0 0 2 2 2 1 Sulfatase protein Phosphodiest PF01663.17 KFP08165.1 - 7.8e-09 35.3 0.7 7.8e-09 35.3 0.5 1.7 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFP08165.1 - 0.073 12.4 0.0 0.2 11.0 0.0 1.7 1 1 0 1 1 1 0 Metalloenzyme superfamily zf-C2H2_4 PF13894.1 KFP08168.1 - 3.3e-07 30.1 8.2 0.0037 17.5 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger SET PF00856.23 KFP08168.1 - 7.4e-06 26.3 0.0 0.0001 22.6 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-C2H2 PF00096.21 KFP08168.1 - 3.6e-05 23.8 12.1 0.019 15.2 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 KFP08168.1 - 0.0011 18.5 1.8 0.0011 18.5 1.3 2.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.2 KFP08168.1 - 0.042 14.0 1.5 6 7.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFP08168.1 - 0.11 12.4 7.5 2.4 8.1 0.5 3.2 4 0 0 4 4 4 0 C2H2-type zinc finger HNH PF01844.18 KFP08168.1 - 0.74 9.7 6.4 2.6 7.9 1.2 2.5 2 0 0 2 2 2 0 HNH endonuclease zf-BED PF02892.10 KFP08168.1 - 1.2 8.9 7.0 3.4 7.4 0.4 2.6 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 KFP08168.1 - 1.4 9.3 19.3 0.42 10.9 1.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain PAS_11 PF14598.1 KFP08169.1 - 2e-40 137.2 0.5 2.8e-35 120.6 0.5 2.6 2 0 0 2 2 2 2 PAS domain DUF1518 PF07469.7 KFP08169.1 - 6.3e-26 90.3 16.2 6.3e-26 90.3 11.2 4.3 3 1 0 3 3 3 1 Domain of unknown function (DUF1518) SRC-1 PF08832.5 KFP08169.1 - 2.1e-25 89.2 5.1 2.1e-25 89.2 3.5 3.1 2 0 0 2 2 2 1 Steroid receptor coactivator Nuc_rec_co-act PF08815.5 KFP08169.1 - 1.7e-22 78.7 0.3 4.3e-22 77.3 0.2 1.7 1 0 0 1 1 1 1 Nuclear receptor coactivator PAS PF00989.19 KFP08169.1 - 1.1e-07 31.6 0.0 7.3e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KFP08169.1 - 1.7e-07 31.5 0.0 6.1e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 KFP08169.1 - 0.00053 20.0 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold HLH PF00010.21 KFP08169.1 - 0.023 14.3 0.6 0.051 13.2 0.4 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain TRAM1 PF08390.6 KFP08170.1 - 1.4e-24 85.3 1.6 3.7e-24 83.9 1.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 KFP08170.1 - 5.9e-23 81.4 18.4 9.5e-23 80.7 12.7 1.3 1 0 0 1 1 1 1 TLC domain DUF3112 PF11309.3 KFP08170.1 - 0.0027 17.4 8.5 0.042 13.6 0.7 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF3112) Lactamase_B PF00753.22 KFP08171.1 - 2.1e-26 92.7 1.5 3e-26 92.2 1.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFP08171.1 - 2.5e-05 23.9 0.6 4.5e-05 23.0 0.4 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Trans_reg_C PF00486.23 KFP08171.1 - 0.099 12.5 0.0 0.33 10.9 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal XK-related PF09815.4 KFP08172.1 - 6.4e-98 327.8 29.5 7.5e-98 327.5 20.4 1.0 1 0 0 1 1 1 1 XK-related protein DUF2136 PF09907.4 KFP08172.1 - 0.069 13.2 0.5 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) PhoQ_Sensor PF08918.5 KFP08172.1 - 0.14 11.6 1.3 2 7.8 0.2 2.3 2 0 0 2 2 2 0 PhoQ Sensor CHGN PF05679.11 KFP08174.1 - 1.4e-180 601.2 0.1 1.6e-180 601.0 0.1 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.9 KFP08174.1 - 2.9e-12 45.8 0.2 7e-12 44.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KFP08174.1 - 2.2e-09 36.7 0.1 5.3e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Fringe PF02434.11 KFP08174.1 - 9.1e-07 28.3 0.1 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Fringe-like UPF0258 PF06789.7 KFP08175.1 - 1.2e-27 96.8 0.0 1.5e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) COX7B PF05392.6 KFP08175.1 - 0.065 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB ADAM_spacer1 PF05986.9 KFP08176.1 - 5.5e-29 100.3 0.0 1.2e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 ADAM-TS Spacer 1 TSP_1 PF00090.14 KFP08176.1 - 5.7e-23 80.7 92.1 2.7e-08 33.7 8.1 7.3 7 1 0 7 7 6 5 Thrombospondin type 1 domain Reprolysin PF01421.14 KFP08176.1 - 2.8e-22 79.2 2.3 2.8e-22 79.2 1.6 3.4 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KFP08176.1 - 6e-22 77.8 0.0 1.4e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin_5 PF13688.1 KFP08176.1 - 8.1e-14 51.9 0.5 2.2e-13 50.6 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFP08176.1 - 3.2e-11 43.1 0.2 1e-10 41.5 0.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFP08176.1 - 2.4e-10 40.9 0.0 6.5e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.6 KFP08176.1 - 6.7e-09 35.8 9.2 6.7e-09 35.8 6.4 3.1 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Reprolysin_2 PF13574.1 KFP08176.1 - 2.8e-08 34.0 1.1 5.6e-08 33.0 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFP08176.1 - 0.00011 21.9 0.4 0.00019 21.2 0.3 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KFP08176.1 - 0.12 11.2 0.2 0.22 10.3 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Ets PF00178.17 KFP08177.1 - 8.1e-26 89.9 0.3 9.4e-26 89.7 0.2 1.1 1 0 0 1 1 1 1 Ets-domain HSF_DNA-bind PF00447.12 KFP08177.1 - 0.01 15.9 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Clathrin PF00637.15 KFP08178.1 - 3.5e-26 91.5 1.1 3.5e-26 91.5 0.8 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.4 KFP08178.1 - 0.00015 21.7 4.6 0.00095 19.1 0.1 3.4 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KFP08178.1 - 0.0015 18.6 0.7 0.0043 17.2 0.5 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 KFP08178.1 - 0.0089 15.8 5.3 0.031 14.1 3.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP08178.1 - 0.067 13.3 2.7 0.21 11.6 1.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFP08178.1 - 2.2 7.9 9.2 0.44 10.2 3.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP08178.1 - 3.9 7.2 11.7 0.37 10.5 4.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain BAR PF03114.13 KFP08179.1 - 2.8e-53 180.8 7.4 4.4e-53 180.1 5.1 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFP08179.1 - 7.8e-10 38.1 0.0 1.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP08179.1 - 7.1e-06 25.3 0.1 6.3e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP08179.1 - 9.5e-05 21.8 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.8 KFP08179.1 - 0.0063 15.8 3.6 0.0097 15.2 2.5 1.3 1 0 0 1 1 1 1 Arfaptin-like domain EzrA PF06160.7 KFP08179.1 - 0.06 11.5 3.7 0.9 7.6 0.2 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HD_3 PF13023.1 KFP08179.1 - 0.075 12.7 3.8 0.084 12.6 0.2 2.4 2 0 0 2 2 2 0 HD domain GAS PF13851.1 KFP08179.1 - 0.26 10.4 3.9 7.6 5.6 0.6 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.8 KFP08179.1 - 1.8 9.3 6.2 18 6.1 0.4 2.6 2 0 0 2 2 2 0 Occludin homology domain IFT57 PF10498.4 KFP08179.1 - 2.5 6.7 10.5 0.25 10.0 0.8 2.6 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Integrin_alpha2 PF08441.7 KFP08181.1 - 4.2e-96 322.5 0.1 6.4e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.18 KFP08181.1 - 4.5e-19 67.5 15.2 5.6e-07 29.0 0.0 4.4 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.1 KFP08181.1 - 1.5e-10 41.2 11.7 9.5e-09 35.4 1.4 2.9 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Integrin_alpha PF00357.15 KFP08181.1 - 0.0011 18.5 0.2 0.0034 17.0 0.2 1.9 1 0 0 1 1 1 1 Integrin alpha cytoplasmic region FG-GAP_2 PF14312.1 KFP08181.1 - 0.015 15.2 15.0 0.021 14.8 0.3 4.7 5 0 0 5 5 5 0 FG-GAP repeat Neuro_bHLH PF12533.3 KFP08182.1 - 2.7e-43 147.5 2.3 2.7e-43 147.5 1.6 2.1 2 0 0 2 2 2 1 Neuronal helix-loop-helix transcription factor HLH PF00010.21 KFP08182.1 - 2.5e-16 59.0 0.8 2.5e-16 59.0 0.6 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4463 PF14703.1 KFP08183.1 - 0.66 10.5 5.3 0.22 12.0 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) PDEase_I PF00233.14 KFP08184.1 - 4.2e-96 321.2 5.0 7.3e-96 320.4 3.5 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 KFP08184.1 - 2.9e-28 97.5 0.0 2.9e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal LSM PF01423.17 KFP08186.1 - 5.5e-19 67.4 1.1 5.9e-19 67.3 0.8 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 KFP08186.1 - 0.058 13.2 0.1 0.071 12.9 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain DCX PF03607.12 KFP08186.1 - 0.074 12.6 0.1 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Doublecortin Avl9 PF09794.4 KFP08187.1 - 2.5e-122 408.0 0.0 2.2e-116 388.4 0.0 2.1 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 KFP08187.1 - 6.1e-09 35.5 0.0 8.4e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DENN PF02141.16 KFP08187.1 - 0.00015 21.5 1.8 0.18 11.5 0.3 2.4 2 0 0 2 2 2 2 DENN (AEX-3) domain DUF2347 PF09804.4 KFP08187.1 - 0.023 14.0 0.3 0.56 9.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Kelch_6 PF13964.1 KFP08188.1 - 1.5e-21 75.5 7.2 6.5e-07 29.2 0.0 5.4 4 2 1 5 5 5 3 Kelch motif BACK PF07707.10 KFP08188.1 - 2.4e-20 72.2 1.4 4.2e-20 71.4 0.9 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_1 PF01344.20 KFP08188.1 - 3.6e-19 68.0 19.1 7.8e-09 34.9 0.0 7.3 6 2 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KFP08188.1 - 3.8e-09 35.9 5.0 0.031 14.0 0.0 5.2 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KFP08188.1 - 1.1e-07 31.8 0.3 0.015 15.4 0.0 4.0 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP08188.1 - 6.9e-05 22.5 8.6 0.31 10.8 0.0 5.3 3 2 1 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP08188.1 - 0.00047 20.0 0.2 3.5 7.6 0.0 3.8 3 0 0 3 3 3 1 Kelch motif zf-CCHC_6 PF15288.1 KFP08190.1 - 0.0083 15.7 0.9 0.018 14.7 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3245 PF11595.3 KFP08190.1 - 0.14 12.4 5.1 0.22 11.8 3.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) zf-CCHC PF00098.18 KFP08190.1 - 2.9 7.9 6.6 0.27 11.2 1.3 1.7 2 0 0 2 2 2 0 Zinc knuckle FKBP_C PF00254.23 KFP08191.1 - 1.2e-115 377.7 0.0 3.7e-27 94.1 0.0 5.1 5 0 0 5 5 5 4 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.27 KFP08191.1 - 4.3e-09 35.0 0.9 0.00038 19.5 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFP08191.1 - 7.4e-06 26.0 4.1 0.00012 22.1 0.6 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFP08191.1 - 0.00018 21.0 0.3 0.29 11.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KFP08191.1 - 0.00026 20.1 0.4 0.2 11.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFP08191.1 - 0.0013 18.3 0.2 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Ribosomal_L21e PF01157.13 KFP08191.1 - 0.36 10.6 1.6 39 4.1 0.0 3.5 4 0 0 4 4 4 0 Ribosomal protein L21e UMPH-1 PF05822.7 KFP08192.1 - 2.7e-120 400.2 4.4 3.1e-120 400.0 3.1 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 KFP08192.1 - 3.1e-05 24.2 0.1 5.2e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_7 PF13840.1 KFP08192.1 - 0.0019 17.6 0.2 3.9 7.0 0.0 3.2 3 0 0 3 3 3 2 ACT domain NIF PF03031.13 KFP08192.1 - 0.006 16.2 0.2 0.78 9.3 0.0 2.6 1 1 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KFP08192.1 - 0.032 14.4 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PHTB1_N PF14727.1 KFP08193.1 - 2.4e-173 576.9 0.0 3e-173 576.5 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.1 KFP08193.1 - 3.5e-148 493.3 2.2 3.5e-148 493.3 1.5 1.4 2 0 0 2 2 2 1 PTHB1 C-terminus VWD PF00094.20 KFP08195.1 - 2.1e-37 128.7 0.2 5.4e-37 127.4 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type D domain VWC PF00093.13 KFP08195.1 - 2.3e-23 82.0 146.9 6.7e-10 38.9 10.3 7.8 6 1 0 6 6 6 5 von Willebrand factor type C domain C8 PF08742.6 KFP08195.1 - 4.2e-19 68.5 13.1 4.2e-19 68.5 9.1 4.3 3 1 1 4 4 4 1 C8 domain TIL PF01826.12 KFP08195.1 - 1.9e-10 40.7 14.2 1.9e-10 40.7 9.8 9.1 4 2 2 6 6 6 1 Trypsin Inhibitor like cysteine rich domain 7tm_1 PF00001.16 KFP08196.1 - 6.8e-41 140.0 17.9 1.6e-39 135.6 12.4 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) T-box PF00907.17 KFP08197.1 - 1.2e-75 253.0 0.1 1.3e-75 252.9 0.1 1.0 1 0 0 1 1 1 1 T-box ubiquitin PF00240.18 KFP08198.1 - 5e-07 29.0 0.1 7.4e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KFP08198.1 - 5.3e-05 23.3 0.0 9.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain AF-4 PF05110.8 KFP08198.1 - 0.0088 13.9 8.1 0.011 13.6 5.6 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Rad60-SLD_2 PF13881.1 KFP08198.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Septin PF00735.13 KFP08199.1 - 1.5e-123 411.3 0.1 1.5e-123 411.3 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFP08199.1 - 1.4e-07 31.5 0.0 6.3e-07 29.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP08199.1 - 2.5e-05 23.5 0.3 0.00012 21.3 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KFP08199.1 - 0.00086 18.4 0.0 0.00086 18.4 0.0 2.5 3 0 0 3 3 3 1 AIG1 family AAA_22 PF13401.1 KFP08199.1 - 0.0039 17.3 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFP08199.1 - 0.0091 15.4 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain Ras PF00071.17 KFP08199.1 - 0.015 14.6 1.5 0.031 13.6 0.0 2.2 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.13 KFP08199.1 - 0.021 14.1 0.0 0.06 12.6 0.0 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 KFP08199.1 - 0.021 15.1 0.0 0.021 15.1 0.0 2.7 3 1 0 3 3 2 0 ABC transporter AAA_16 PF13191.1 KFP08199.1 - 0.027 14.4 0.5 0.056 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 KFP08199.1 - 0.027 14.9 0.0 0.027 14.9 0.0 2.7 3 1 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 KFP08199.1 - 0.036 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 KFP08199.1 - 0.038 13.1 0.0 0.038 13.1 0.0 2.8 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region MobB PF03205.9 KFP08199.1 - 0.043 13.5 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KFP08199.1 - 0.17 11.6 10.0 15 5.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KFP08199.1 - 0.28 10.6 0.0 0.28 10.6 0.0 2.4 2 1 0 2 2 1 0 FtsK/SpoIIIE family FliT PF05400.8 KFP08199.1 - 0.72 10.3 14.7 0.25 11.7 7.7 2.0 2 0 0 2 2 2 0 Flagellar protein FliT DUF2937 PF11157.3 KFP08199.1 - 3.5 6.9 7.8 4.4 6.6 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) HHH_3 PF12836.2 KFP08200.1 - 8.4e-42 140.9 0.2 1.5e-20 72.8 0.1 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH PF00633.18 KFP08200.1 - 1.7e-17 62.0 0.1 2.4e-06 26.8 0.0 3.9 4 0 0 4 4 4 3 Helix-hairpin-helix motif Exo_endo_phos PF03372.18 KFP08200.1 - 5.7e-10 39.5 0.1 7.9e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_5 PF14520.1 KFP08200.1 - 6e-09 35.9 0.0 1.8e-06 27.9 0.0 3.6 2 1 1 3 3 3 2 Helix-hairpin-helix domain HHH_2 PF12826.2 KFP08200.1 - 6.9e-09 35.4 0.1 0.0056 16.5 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif T2SK PF03934.8 KFP08200.1 - 2.7e-08 33.3 0.0 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein K HHH_6 PF14579.1 KFP08200.1 - 3.4e-08 33.4 0.0 0.00022 21.1 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif Exo_endo_phos_2 PF14529.1 KFP08200.1 - 0.00042 19.9 0.4 0.0012 18.4 0.3 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PsbU PF06514.6 KFP08200.1 - 0.0026 17.5 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) DUF1704 PF08014.6 KFP08201.1 - 5.7e-15 55.1 0.0 7.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) Anillin PF08174.6 KFP08202.1 - 1.2e-21 77.2 0.1 4.2e-21 75.4 0.1 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KFP08202.1 - 3.8e-15 55.9 0.7 1.1e-14 54.4 0.1 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KFP08202.1 - 0.00099 19.3 0.7 0.003 17.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Lipase_GDSL PF00657.17 KFP08203.1 - 2e-14 53.9 0.0 3.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFP08203.1 - 2.7e-06 27.6 0.0 6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cu-binding_MopE PF11617.3 KFP08203.1 - 0.0098 15.6 0.6 0.034 13.9 0.4 1.9 1 0 0 1 1 1 1 Protein metal binding site DUF3361 PF11841.3 KFP08204.1 - 2.1e-72 242.0 2.7 5.1e-72 240.8 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.8 KFP08204.1 - 3.5e-49 166.6 0.6 6.7e-49 165.6 0.4 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family FERM_N PF09379.5 KFP08204.1 - 0.03 14.3 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 FERM N-terminal domain BCL_N PF04714.8 KFP08205.1 - 0.066 12.7 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Thioredoxin PF00085.15 KFP08207.1 - 1.8e-06 27.5 0.2 2.3e-06 27.2 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KFP08207.1 - 0.032 13.7 0.0 0.032 13.7 0.0 1.0 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.1 KFP08207.1 - 0.034 14.2 0.0 0.036 14.1 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 KFP08207.1 - 0.038 13.6 0.0 0.038 13.6 0.0 1.0 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.19 KFP08207.1 - 0.056 13.4 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin NTR PF01759.16 KFP08208.1 - 1.2e-16 60.2 3.8 1.3e-16 60.0 0.3 2.1 1 1 1 2 2 2 1 UNC-6/NTR/C345C module PEHE PF15275.1 KFP08208.1 - 0.24 11.8 3.0 0.51 10.8 2.1 1.5 1 0 0 1 1 1 0 PEHE domain Ependymin PF00811.13 KFP08209.1 - 8.5e-40 135.5 0.2 9.5e-40 135.3 0.1 1.0 1 0 0 1 1 1 1 Ependymin Fumble PF03630.9 KFP08211.1 - 7.9e-145 481.9 0.0 8.9e-145 481.8 0.0 1.0 1 0 0 1 1 1 1 Fumble LRR_8 PF13855.1 KFP08212.1 - 4.6e-87 285.7 75.2 1.2e-14 53.7 0.8 9.4 4 3 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.2 KFP08212.1 - 2.7e-42 141.7 62.1 2.7e-08 33.2 0.1 11.4 6 3 9 15 15 15 14 Leucine Rich repeats (2 copies) EGF PF00008.22 KFP08212.1 - 8.9e-29 99.0 95.8 1.4e-07 31.3 4.0 8.6 9 0 0 9 9 7 6 EGF-like domain LRR_1 PF00560.28 KFP08212.1 - 1.7e-22 76.0 51.5 0.29 11.3 0.0 18.4 20 0 0 20 20 19 10 Leucine Rich Repeat Laminin_G_2 PF02210.19 KFP08212.1 - 1.1e-18 67.4 0.1 1.8e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain LRRNT PF01462.13 KFP08212.1 - 1.6e-18 65.6 44.3 7.4e-09 34.8 2.2 7.0 7 0 0 7 7 7 3 Leucine rich repeat N-terminal domain Laminin_G_1 PF00054.18 KFP08212.1 - 1.5e-14 54.1 0.1 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain LRR_9 PF14580.1 KFP08212.1 - 1.7e-12 47.2 21.8 0.0014 18.2 1.0 5.7 4 2 2 6 6 6 4 Leucine-rich repeat hEGF PF12661.2 KFP08212.1 - 4.8e-08 32.5 63.7 0.0014 18.5 1.6 9.1 8 0 0 8 8 6 5 Human growth factor-like EGF LRR_6 PF13516.1 KFP08212.1 - 1e-07 31.2 42.8 0.93 9.7 0.1 15.8 12 5 3 15 15 15 1 Leucine Rich repeat LRR_7 PF13504.1 KFP08212.1 - 0.00082 19.1 50.3 8.5 7.0 0.0 14.9 17 0 0 17 17 14 1 Leucine rich repeat EGF_CA PF07645.10 KFP08212.1 - 0.0093 15.9 5.3 0.0093 15.9 3.7 9.7 7 1 3 10 10 8 1 Calcium-binding EGF domain EGF_3 PF12947.2 KFP08212.1 - 0.012 15.5 4.0 0.012 15.5 2.8 9.6 10 0 0 10 10 8 0 EGF domain Laminin_G_3 PF13385.1 KFP08212.1 - 0.02 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily HSP70 PF00012.15 KFP08213.1 - 4.9e-255 847.0 8.3 5.6e-255 846.9 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFP08213.1 - 1.8e-18 66.2 1.8 5.8e-16 58.0 0.3 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KFP08213.1 - 9.8e-05 22.0 0.2 0.00019 21.0 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFP08213.1 - 0.00016 21.4 7.7 0.58 9.9 0.6 4.6 4 1 0 4 4 4 2 Cell division protein FtsA Vinculin PF01044.14 KFP08214.1 - 0 1038.2 37.6 3.5e-215 717.1 16.9 2.1 1 1 1 2 2 2 2 Vinculin family DivIC PF04977.10 KFP08214.1 - 5.9 6.4 8.5 0.77 9.2 0.5 3.5 3 0 0 3 3 3 0 Septum formation initiator LRR_8 PF13855.1 KFP08215.1 - 6e-46 154.0 49.0 3.9e-14 52.1 2.2 5.2 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KFP08215.1 - 1.9e-32 110.2 38.3 3.7e-07 29.6 3.8 6.9 2 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 KFP08215.1 - 2.5e-23 82.1 0.3 7.6e-10 38.5 0.0 3.4 2 1 2 4 4 4 3 Leucine rich repeats (6 copies) LRR_1 PF00560.28 KFP08215.1 - 8.3e-21 70.8 34.0 0.014 15.2 1.0 10.8 11 0 0 11 11 11 8 Leucine Rich Repeat LRR_7 PF13504.1 KFP08215.1 - 7e-09 34.4 39.6 1 9.8 0.5 10.7 11 0 0 11 11 11 6 Leucine rich repeat LRR_6 PF13516.1 KFP08215.1 - 1.4e-08 33.9 36.4 0.4 10.8 0.8 10.4 10 1 1 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 KFP08215.1 - 3.3e-08 33.3 5.5 0.018 14.6 0.3 3.6 1 1 3 4 4 4 3 Leucine-rich repeat LRRNT PF01462.13 KFP08215.1 - 0.0045 16.4 1.8 0.0045 16.4 1.3 2.6 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain Fes1 PF08609.5 KFP08216.1 - 0.0086 16.5 3.0 0.011 16.1 1.0 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 CDC14 PF08045.6 KFP08216.1 - 0.02 14.0 7.2 0.031 13.4 0.8 2.9 1 1 2 3 3 3 0 Cell division control protein 14, SIN component HEAT_2 PF13646.1 KFP08216.1 - 0.078 13.2 0.5 0.38 11.0 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.1 KFP08216.1 - 0.096 13.2 0.2 0.28 11.7 0.2 1.9 1 0 0 1 1 1 0 HEAT-like repeat SIR2_2 PF13289.1 KFP08216.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 SIR2-like domain DUF2937 PF11157.3 KFP08216.1 - 0.12 11.6 2.6 0.98 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) RRM_5 PF13893.1 KFP08217.1 - 5.3e-28 96.6 0.0 3.4e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP08217.1 - 1.4e-19 69.8 0.0 1.4e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP08217.1 - 7e-09 35.1 0.0 0.0005 19.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KFP08217.1 - 0.14 12.3 7.3 0.15 12.2 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP08217.1 - 4.4 7.6 10.3 8.1 6.8 1.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PAM2 PF07145.10 KFP08218.1 - 9.7e-08 31.0 0.8 3e-07 29.4 0.5 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RE_HindIII PF09518.5 KFP08218.1 - 0.023 13.6 1.5 0.028 13.3 1.1 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease rve_3 PF13683.1 KFP08218.1 - 0.27 10.7 1.5 1.4 8.4 0.5 2.0 1 1 1 2 2 2 0 Integrase core domain Xan_ur_permease PF00860.15 KFP08219.1 - 1.4e-86 290.4 22.9 1.8e-86 290.1 15.9 1.1 1 0 0 1 1 1 1 Permease family MerE PF05052.7 KFP08219.1 - 0.25 11.3 3.3 0.23 11.4 0.1 2.6 3 0 0 3 3 3 0 MerE protein DUF3456 PF11938.3 KFP08220.1 - 0.00017 21.6 0.0 0.066 13.2 0.0 2.4 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP Cytochrome_C7 PF14522.1 KFP08220.1 - 0.098 12.3 0.3 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 DUF1977 PF09320.6 KFP08221.1 - 4.5e-34 116.9 4.5 4.5e-34 116.9 3.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KFP08221.1 - 3.5e-26 90.7 0.3 8.6e-26 89.4 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain GntP_permease PF02447.11 KFP08221.1 - 0.028 12.9 0.0 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 GntP family permease DUF401 PF04165.7 KFP08221.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) Sel1 PF08238.7 KFP08222.1 - 1.7e-26 91.9 20.9 1.7e-09 37.9 0.1 5.2 5 0 0 5 5 5 4 Sel1 repeat TPR_11 PF13414.1 KFP08222.1 - 0.0014 18.2 13.0 0.0089 15.6 1.5 3.8 1 1 2 3 3 3 1 TPR repeat TPR_16 PF13432.1 KFP08222.1 - 0.0018 18.9 20.1 0.28 11.9 0.1 4.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFP08222.1 - 0.0057 17.0 7.4 4.6 7.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFP08222.1 - 0.02 14.8 16.7 0.75 9.8 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFP08222.1 - 0.41 10.5 6.8 8 6.5 0.1 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFP08222.1 - 0.56 9.9 9.5 12 5.6 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP08222.1 - 1.1 9.2 7.7 0.91 9.5 0.6 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFP08222.1 - 4 8.3 12.2 40 5.2 2.5 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Cadherin PF00028.12 KFP08224.1 - 3.2e-116 379.8 3.2 1.5e-22 79.6 0.0 7.4 7 0 0 7 7 7 7 Cadherin domain Protocadherin PF08374.6 KFP08224.1 - 1.2e-85 286.7 1.4 3.3e-85 285.2 1.0 1.9 1 0 0 1 1 1 1 Protocadherin Cadherin_2 PF08266.7 KFP08224.1 - 4.3e-13 48.6 0.0 1.3e-05 24.6 0.0 5.7 6 0 0 6 6 6 2 Cadherin-like DUF1510 PF07423.6 KFP08224.1 - 0.014 14.7 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MLANA PF14991.1 KFP08224.1 - 0.047 13.7 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Mid2 PF04478.7 KFP08224.1 - 0.082 12.3 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 KFP08224.1 - 0.085 13.2 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KFP08224.1 - 0.12 10.5 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 KFP08224.1 - 0.13 12.4 0.6 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Syndecan PF01034.15 KFP08224.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain RhoGAP PF00620.22 KFP08226.1 - 1.2e-45 154.8 0.1 2.4e-45 153.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KFP08226.1 - 8.3e-21 74.1 3.1 0.00012 22.2 0.1 5.6 6 0 0 6 6 6 3 PH domain ArfGap PF01412.13 KFP08226.1 - 5.5e-15 55.1 0.0 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SAM_2 PF07647.12 KFP08226.1 - 7.9e-12 44.8 0.0 3.9e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP08226.1 - 2.9e-11 43.3 0.0 8.7e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.18 KFP08226.1 - 4.8e-11 42.9 0.1 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_11 PF15413.1 KFP08226.1 - 0.00074 19.7 0.8 1.3 9.3 0.0 3.6 4 0 0 4 4 4 2 Pleckstrin homology domain PH_6 PF15406.1 KFP08226.1 - 0.00091 19.2 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFP08226.1 - 0.011 15.8 0.0 0.068 13.2 0.0 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain PH_3 PF14593.1 KFP08226.1 - 0.019 14.8 0.5 0.13 12.1 0.0 2.5 3 0 0 3 3 3 0 PH domain 7tm_1 PF00001.16 KFP08227.1 - 7.8e-35 120.2 10.9 9.4e-35 119.9 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP08227.1 - 0.0017 17.5 6.9 0.0023 17.1 4.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_4 PF13853.1 KFP08227.1 - 0.0018 18.1 4.4 0.0033 17.2 3.1 1.6 1 0 0 1 1 1 1 Olfactory receptor TatC PF00902.13 KFP08227.1 - 0.0065 15.8 6.7 0.011 15.1 4.7 1.5 1 1 0 1 1 1 1 Sec-independent protein translocase protein (TatC) 7TM_GPCR_Srw PF10324.4 KFP08227.1 - 0.017 14.2 5.4 0.074 12.1 1.0 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw MatE PF01554.13 KFP08227.1 - 0.062 12.9 5.0 0.2 11.2 3.6 1.7 1 1 0 1 1 1 0 MatE DUF2919 PF11143.3 KFP08227.1 - 0.62 9.8 9.5 0.079 12.7 3.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) RELT PF12606.3 KFP08228.1 - 2e-19 68.4 0.0 3.8e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 SieB PF14163.1 KFP08228.1 - 0.033 13.7 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B ocr PF08684.5 KFP08228.1 - 0.14 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA mimic ocr Hist_deacetyl PF00850.14 KFP08229.1 - 2.2e-76 257.1 0.1 3.4e-76 256.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RrnaAD PF00398.15 KFP08231.1 - 2.6e-52 177.4 0.0 3e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KFP08231.1 - 2.6e-10 40.3 0.0 4.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP08231.1 - 2.6e-07 31.2 0.0 5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP08231.1 - 5.4e-06 26.0 0.0 1.6e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFP08231.1 - 0.00033 20.0 0.0 0.00064 19.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KFP08231.1 - 0.00096 19.6 0.0 0.0057 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFP08231.1 - 0.0013 19.1 0.0 0.0037 17.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KFP08231.1 - 0.004 16.7 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 KFP08231.1 - 0.0052 16.5 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFP08231.1 - 0.008 15.7 0.1 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 KFP08231.1 - 0.017 14.7 0.0 0.057 13.0 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein DREV PF05219.7 KFP08231.1 - 0.041 12.7 0.0 0.096 11.5 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase Methyltransf_4 PF02390.12 KFP08231.1 - 0.045 12.7 0.0 0.092 11.7 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase DERM PF14704.1 KFP08231.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Dermatopontin Ubie_methyltran PF01209.13 KFP08231.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family IBN_N PF03810.14 KFP08232.1 - 1.8e-20 72.6 1.5 1.3e-19 69.9 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KFP08232.1 - 0.0048 17.1 0.0 0.042 14.1 0.0 2.6 1 1 1 2 2 2 1 HEAT repeats Xpo1 PF08389.7 KFP08232.1 - 0.0081 16.0 10.3 0.036 13.9 0.0 4.8 5 0 0 5 5 5 2 Exportin 1-like protein HEAT_EZ PF13513.1 KFP08232.1 - 0.054 13.9 0.9 0.74 10.3 0.0 3.4 4 0 0 4 4 4 0 HEAT-like repeat Yae1_N PF09811.4 KFP08234.1 - 1.1e-18 66.4 57.7 1.5e+04 -18.3 40.0 5.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal 7tm_1 PF00001.16 KFP08235.1 - 3.8e-94 314.5 5.3 4.6e-94 314.3 3.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP08235.1 - 9.4e-14 51.1 1.0 1.7e-13 50.3 0.7 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.4 KFP08235.1 - 2.4e-07 30.1 0.3 6.7e-07 28.7 0.2 1.7 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Cyto_ox_2 PF02322.10 KFP08235.1 - 0.0016 17.7 8.6 0.029 13.5 0.1 2.4 3 0 0 3 3 3 2 Cytochrome oxidase subunit II 7TM_GPCR_Srx PF10328.4 KFP08235.1 - 0.0033 16.5 3.5 0.0033 16.5 2.4 2.5 2 2 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF1761 PF08570.5 KFP08235.1 - 0.03 14.3 0.0 0.29 11.1 0.0 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF1761) DUF1049 PF06305.6 KFP08235.1 - 1.3 8.5 6.7 5.5 6.5 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Syntaxin_2 PF14523.1 KFP08236.1 - 0.0025 17.8 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 2 Syntaxin-like protein Occludin_ELL PF07303.8 KFP08236.1 - 0.044 14.5 0.0 0.7 10.6 0.0 2.1 2 0 0 2 2 2 0 Occludin homology domain zf-CCHC_3 PF13917.1 KFP08237.1 - 4.9e-08 32.5 0.1 5.1e-08 32.5 0.1 1.3 1 1 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFP08237.1 - 0.12 12.3 3.3 0.17 11.8 2.3 1.2 1 0 0 1 1 1 0 Zinc knuckle Luteo_PO PF04662.8 KFP08237.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Luteovirus P0 protein Pro_isomerase PF00160.16 KFP08238.1 - 3.6e-50 170.2 0.1 7.5e-50 169.1 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KFP08238.1 - 4.4e-16 58.0 4.2 0.0041 16.9 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Arf PF00025.16 KFP08239.1 - 6.6e-71 237.1 0.5 1.4e-70 236.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 KFP08239.1 - 7.1e-12 45.0 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KFP08239.1 - 2.3e-11 43.2 0.0 4.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KFP08239.1 - 3.7e-09 35.7 0.4 1.4e-07 30.5 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 KFP08239.1 - 4.6e-08 33.5 0.0 1.2e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFP08239.1 - 2.2e-07 30.2 0.0 5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region zf-RING_5 PF14634.1 KFP08239.1 - 2e-06 27.4 2.1 2e-06 27.4 1.4 4.2 3 1 0 3 3 2 1 zinc-RING finger domain zf-B_box PF00643.19 KFP08239.1 - 3e-06 27.0 5.0 3e-06 27.0 3.4 3.9 4 0 0 4 4 3 2 B-box zinc finger zf-C3HC4 PF00097.20 KFP08239.1 - 0.0003 20.3 1.3 0.0003 20.3 0.9 3.7 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP08239.1 - 0.00056 19.6 4.1 0.00056 19.6 2.9 4.2 4 1 1 5 5 3 1 Ring finger domain MMR_HSR1 PF01926.18 KFP08239.1 - 0.00058 19.7 0.1 0.0045 16.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-RING_UBOX PF13445.1 KFP08239.1 - 0.00061 19.4 2.9 0.00061 19.4 2.0 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFP08239.1 - 0.0015 18.5 3.6 0.0015 18.5 2.5 4.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP08239.1 - 0.022 14.6 2.9 0.022 14.6 2.0 4.1 4 0 0 4 4 3 0 zinc finger of C3HC4-type, RING IBR PF01485.16 KFP08239.1 - 0.03 14.1 1.2 0.03 14.1 0.8 4.0 4 0 0 4 4 3 0 IBR domain DUF974 PF06159.8 KFP08241.1 - 2.4e-85 285.9 0.8 3.1e-85 285.5 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.17 KFP08241.1 - 0.0071 16.3 0.3 0.26 11.3 0.0 2.9 3 0 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain Trs65 PF12735.2 KFP08241.1 - 0.037 13.3 0.3 1.9 7.7 0.0 3.1 3 1 1 4 4 4 0 TRAPP trafficking subunit Trs65 TPR_11 PF13414.1 KFP08242.1 - 1.2e-30 104.9 8.4 1.5e-22 78.9 2.8 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFP08242.1 - 6e-30 101.6 10.7 6.7e-10 38.1 1.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFP08242.1 - 2.5e-23 80.0 6.6 5.2e-07 29.0 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFP08242.1 - 8.9e-16 56.3 1.2 0.00018 21.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFP08242.1 - 1e-15 56.5 5.2 1.9e-07 30.7 0.6 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFP08242.1 - 1.7e-11 43.0 9.1 0.00018 21.0 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFP08242.1 - 2.1e-11 44.1 0.1 2.7e-06 27.8 0.0 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP08242.1 - 3.3e-11 42.7 0.0 0.0066 16.9 0.0 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFP08242.1 - 4.5e-11 42.5 4.4 1.9e-07 30.9 0.7 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP08242.1 - 1.1e-10 41.6 3.0 1.5e-06 28.4 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFP08242.1 - 6.1e-09 35.6 0.2 9.5e-06 25.3 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TOM20_plant PF06552.7 KFP08242.1 - 1.9e-05 24.3 2.5 0.0062 16.1 0.1 3.1 2 1 1 3 3 2 2 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.4 KFP08242.1 - 2.2e-05 23.5 0.5 0.92 8.8 0.0 3.5 3 0 0 3 3 3 1 SHNi-TPR TPR_6 PF13174.1 KFP08242.1 - 4.1e-05 23.7 1.0 0.91 10.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 KFP08242.1 - 0.00011 21.9 6.4 0.13 12.1 0.4 3.4 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 KFP08242.1 - 0.00022 21.3 4.3 0.00022 21.3 3.0 2.0 2 1 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KFP08242.1 - 0.0012 18.6 8.7 0.17 11.7 0.2 3.7 3 1 1 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 KFP08242.1 - 0.0046 17.2 0.1 0.027 14.7 0.0 2.0 1 1 1 2 2 2 1 Bacterial transcriptional activator domain DUF627 PF04781.7 KFP08242.1 - 0.0047 16.5 2.2 0.02 14.5 0.2 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF627) Pectate_lyase_2 PF06917.7 KFP08242.1 - 0.0078 14.5 0.1 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic pectate lyase FAT PF02259.18 KFP08242.1 - 0.01 14.8 0.1 0.018 14.0 0.1 1.4 1 0 0 1 1 1 0 FAT domain TPR_15 PF13429.1 KFP08242.1 - 0.063 12.3 0.2 7.5 5.5 0.0 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.2 KFP08242.1 - 0.11 12.3 1.6 22 4.8 0.4 3.1 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) XPC-binding PF09280.6 KFP08242.1 - 0.59 9.6 15.4 0.8 9.2 2.3 2.7 3 0 0 3 3 3 0 XPC-binding domain Peptidase_M3 PF01432.15 KFP08243.1 - 1.9e-152 508.4 0.2 2.6e-152 508.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 LRR_4 PF12799.2 KFP08244.1 - 1.2e-44 149.2 43.3 3.8e-08 32.7 1.5 10.0 4 3 7 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP08244.1 - 1.3e-40 136.9 27.4 2.9e-09 36.5 0.1 6.8 3 2 1 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 KFP08244.1 - 1.2e-24 82.5 32.6 0.074 13.1 0.1 16.2 16 0 0 16 16 16 7 Leucine Rich Repeat LRR_7 PF13504.1 KFP08244.1 - 8.8e-15 52.2 29.1 7.2 7.2 0.0 14.6 15 0 0 15 15 15 3 Leucine rich repeat PDZ PF00595.19 KFP08244.1 - 9.1e-13 48.2 0.1 2.2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) LRR_5 PF13306.1 KFP08244.1 - 2.5e-06 27.1 4.7 0.01 15.5 0.2 3.8 2 1 1 4 4 4 3 Leucine rich repeats (6 copies) PDZ_2 PF13180.1 KFP08244.1 - 0.00016 21.4 0.6 0.0011 18.8 0.0 2.7 4 0 0 4 4 4 1 PDZ domain LRR_6 PF13516.1 KFP08244.1 - 0.0091 15.9 27.8 3.7 7.9 0.0 10.3 11 0 0 11 11 11 1 Leucine Rich repeat RRM_6 PF14259.1 KFP08245.1 - 1.6e-14 53.6 0.0 2.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP08245.1 - 4.7e-14 51.7 0.1 8.5e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP08245.1 - 4.2e-09 36.1 0.0 6.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1908 PF08926.6 KFP08247.1 - 7.3e-143 474.4 0.6 7.3e-143 474.4 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Pkinase PF00069.20 KFP08247.1 - 1e-64 218.2 0.0 2.1e-64 217.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08247.1 - 1.7e-27 96.1 0.0 3.3e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ PF00595.19 KFP08247.1 - 9.5e-10 38.5 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP08247.1 - 3e-07 30.2 0.1 7.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.1 KFP08247.1 - 3.3e-05 22.9 0.0 0.00023 20.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFP08247.1 - 0.00013 21.7 0.0 0.033 13.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 KFP08247.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain SH2 PF00017.19 KFP08249.1 - 1.8e-42 143.0 0.1 1.4e-21 76.0 0.0 2.6 2 0 0 2 2 2 2 SH2 domain RhoGAP PF00620.22 KFP08249.1 - 2.9e-33 114.6 2.1 4e-33 114.1 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.23 KFP08249.1 - 9e-06 24.9 1.6 0.00052 19.3 0.1 2.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KFP08249.1 - 0.00028 20.2 0.0 0.00085 18.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain DUF4201 PF13870.1 KFP08249.1 - 0.0012 18.3 13.1 0.0055 16.1 1.4 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) SH3_9 PF14604.1 KFP08249.1 - 0.0022 17.5 0.7 0.0075 15.8 0.5 2.0 1 1 0 1 1 1 1 Variant SH3 domain Laminin_I PF06008.9 KFP08249.1 - 0.012 15.0 10.3 0.022 14.0 7.1 1.4 1 0 0 1 1 1 0 Laminin Domain I IncA PF04156.9 KFP08249.1 - 0.071 12.7 17.6 0.21 11.1 12.2 1.8 1 1 0 1 1 1 0 IncA protein DUF1338 PF07063.8 KFP08249.1 - 0.46 9.4 5.2 1.6 7.7 3.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1338) Troponin PF00992.15 KFP08249.1 - 1.7 8.7 16.6 1.4 8.9 10.3 1.8 1 1 1 2 2 2 0 Troponin Seryl_tRNA_N PF02403.17 KFP08249.1 - 1.9 8.5 12.1 2.4 8.1 5.2 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 KFP08249.1 - 2.7 5.7 10.4 4.7 4.9 7.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 KFP08249.1 - 3.7 7.3 16.5 5.7 6.6 4.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cation_efflux PF01545.16 KFP08250.1 - 6.7e-57 192.7 7.5 6.7e-57 192.7 5.2 2.9 2 1 1 3 3 3 1 Cation efflux family DUF2946 PF11162.3 KFP08250.1 - 0.00047 20.3 1.7 0.0018 18.4 1.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) DUF2638 PF10937.3 KFP08251.1 - 0.012 16.6 0.1 0.013 16.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) Pkinase PF00069.20 KFP08252.1 - 8.9e-72 241.3 0.0 1e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08252.1 - 3.6e-29 101.6 0.0 4.5e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP08252.1 - 1.7e-05 23.9 0.0 0.00013 21.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KFP08252.1 - 9.9e-05 21.3 0.2 0.0012 17.7 0.1 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.18 KFP08252.1 - 0.0062 16.2 0.1 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFP08252.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Serinc PF03348.10 KFP08253.1 - 5.5e-140 466.8 31.2 6.2e-140 466.6 21.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3593 PF12159.3 KFP08253.1 - 0.35 10.6 9.6 1.7 8.4 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3593) Tom37_C PF11801.3 KFP08254.1 - 6.7e-16 58.6 0.3 1.5e-10 41.2 0.0 2.5 2 1 1 3 3 3 2 Tom37 C-terminal domain GST_C_3 PF14497.1 KFP08254.1 - 1.2e-08 35.2 0.0 4.9e-08 33.3 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFP08254.1 - 1.6e-06 27.8 0.0 5.3e-06 26.2 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFP08254.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain fn3 PF00041.16 KFP08255.1 - 3.4e-13 49.5 0.0 5.5e-07 29.6 0.0 2.8 2 0 0 2 2 2 2 Fibronectin type III domain SPRY PF00622.23 KFP08255.1 - 3.9e-07 30.1 0.0 8.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 SPRY domain DUF2435 PF10363.4 KFP08255.1 - 0.12 12.3 1.1 2.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) PAP_assoc PF03828.14 KFP08257.1 - 3e-17 62.2 0.1 1.2e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFP08257.1 - 2.8e-05 24.3 0.0 5.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain WH1 PF00568.18 KFP08258.1 - 5.8e-35 119.3 0.3 1.1e-34 118.4 0.2 1.5 1 0 0 1 1 1 1 WH1 domain GAS PF13851.1 KFP08258.1 - 0.00087 18.5 51.4 0.0036 16.5 17.8 2.5 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 KFP08258.1 - 0.00088 18.9 19.3 0.00088 18.9 13.4 3.2 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 KFP08258.1 - 0.0019 18.2 23.1 0.0042 17.1 8.8 3.4 2 1 2 4 4 4 1 Domain of unknown function (DUF4164) Atg14 PF10186.4 KFP08258.1 - 0.0034 16.3 18.5 0.0066 15.4 12.8 1.6 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF445 PF04286.7 KFP08258.1 - 0.0093 15.5 14.5 0.014 14.9 10.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Fib_alpha PF08702.5 KFP08258.1 - 0.0097 16.0 15.1 0.058 13.5 5.3 2.6 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF812 PF05667.6 KFP08258.1 - 0.01 14.4 19.7 0.015 13.8 13.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 KFP08258.1 - 0.013 14.7 7.4 0.54 9.3 1.2 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-K PF11802.3 KFP08258.1 - 0.016 14.4 14.2 0.028 13.6 9.9 1.4 1 0 0 1 1 1 0 Centromere-associated protein K DMPK_coil PF08826.5 KFP08258.1 - 0.022 14.6 9.6 0.022 14.6 6.6 3.4 2 1 1 3 3 3 0 DMPK coiled coil domain like FUSC PF04632.7 KFP08258.1 - 0.045 12.1 5.6 0.057 11.8 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nsp1_C PF05064.8 KFP08258.1 - 0.046 13.3 23.1 0.87 9.2 7.4 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region ATG16 PF08614.6 KFP08258.1 - 0.047 13.5 36.8 0.3 10.9 5.6 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 KFP08258.1 - 0.085 12.6 13.3 0.16 11.8 5.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 KFP08258.1 - 0.095 12.9 11.8 0.29 11.4 0.6 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.15 KFP08258.1 - 0.13 11.3 28.0 0.0067 15.5 14.7 2.0 2 0 0 2 2 2 0 Tropomyosin Laminin_II PF06009.7 KFP08258.1 - 0.14 11.9 19.4 0.024 14.3 5.6 2.9 2 1 1 3 3 3 0 Laminin Domain II DUF4140 PF13600.1 KFP08258.1 - 0.37 11.2 21.6 0.92 9.9 3.3 3.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Syntaxin-6_N PF09177.6 KFP08258.1 - 0.45 10.9 16.4 0.62 10.5 2.9 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal IncA PF04156.9 KFP08258.1 - 0.53 9.8 40.4 0.048 13.2 8.3 2.9 2 1 1 3 3 3 0 IncA protein DivIC PF04977.10 KFP08258.1 - 0.63 9.5 32.6 0.14 11.7 3.0 4.7 3 2 2 5 5 5 0 Septum formation initiator BLOC1_2 PF10046.4 KFP08258.1 - 0.9 9.7 26.1 0.11 12.6 3.8 3.6 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3461 PF11944.3 KFP08258.1 - 1.1 9.1 13.9 0.21 11.4 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) DUF1465 PF07323.7 KFP08258.1 - 1.3 8.6 12.2 0.19 11.2 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) DUF4559 PF15112.1 KFP08258.1 - 1.9 7.5 21.2 0.51 9.4 8.9 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4559) APG6 PF04111.7 KFP08258.1 - 2.5 7.0 36.2 0.18 10.8 13.3 2.5 2 1 1 3 3 3 0 Autophagy protein Apg6 AAA_13 PF13166.1 KFP08258.1 - 2.6 6.3 27.2 0.28 9.5 15.0 1.9 1 1 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 KFP08258.1 - 3 7.8 29.0 0.066 13.2 6.6 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2968 PF11180.3 KFP08258.1 - 3.4 7.0 28.2 0.98 8.7 2.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) ADIP PF11559.3 KFP08258.1 - 5.7 6.8 36.4 0.28 11.0 9.0 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 KFP08258.1 - 6.5 6.6 19.4 4.4 7.1 0.6 3.5 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TACC PF05010.9 KFP08258.1 - 6.6 6.4 25.2 2.6 7.7 14.5 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) CENP-F_leu_zip PF10473.4 KFP08258.1 - 6.7 6.5 37.5 0.46 10.3 18.4 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 KFP08258.1 - 7 7.0 28.0 2.5 8.4 1.6 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF972) DUF342 PF03961.8 KFP08258.1 - 7.3 4.8 21.5 17 3.6 13.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF948 PF06103.6 KFP08258.1 - 7.6 6.4 11.2 2.9 7.7 1.8 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 KFP08258.1 - 8.6 6.2 41.1 0.27 11.0 5.9 3.9 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding Fzo_mitofusin PF04799.8 KFP08258.1 - 8.7 5.6 18.0 13 5.1 6.7 2.7 1 1 1 2 2 2 0 fzo-like conserved region DUF3584 PF12128.3 KFP08258.1 - 9.4 3.4 31.1 1.4 6.1 16.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) DUF4279 PF14106.1 KFP08258.1 - 9.9 6.0 7.9 12 5.8 0.6 3.3 2 1 1 4 4 4 0 Domain of unknown function (DUF4279) TPR_MLP1_2 PF07926.7 KFP08258.1 - 9.9 5.9 34.3 11 5.8 11.1 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein WH2 PF02205.15 KFP08259.1 - 0.0018 17.8 0.3 0.0018 17.8 0.2 3.5 4 0 0 4 4 4 1 WH2 motif DUF3782 PF12644.2 KFP08259.1 - 4.9 7.0 7.1 1.7 8.5 1.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) S-methyl_trans PF02574.11 KFP08261.1 - 1.3e-68 231.5 0.0 1.7e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DAO PF01266.19 KFP08262.1 - 4e-77 259.5 0.0 5.5e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KFP08262.1 - 4.7e-59 199.2 0.0 7.5e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFP08262.1 - 1.8e-22 79.1 0.0 4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 KFP08262.1 - 1.8e-08 34.3 0.0 4e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Pyr_redox_3 PF13738.1 KFP08262.1 - 5.7e-08 33.0 0.0 3.2e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFP08262.1 - 2e-05 24.5 0.9 0.0002 21.3 0.5 2.6 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFP08262.1 - 3.2e-05 22.9 0.1 7e-05 21.8 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KFP08262.1 - 0.00024 20.2 0.2 0.00048 19.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KFP08262.1 - 0.0013 17.8 0.3 0.0023 17.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFP08262.1 - 0.0044 16.9 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFP08262.1 - 0.015 15.6 0.2 0.063 13.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFP08262.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KFP08262.1 - 0.019 13.9 0.1 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFP08262.1 - 0.043 13.5 0.1 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KFP08262.1 - 0.054 11.9 0.1 0.64 8.4 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.15 KFP08262.1 - 0.12 12.5 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KFP08262.1 - 0.18 11.7 0.0 0.8 9.7 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Sulfatase PF00884.18 KFP08263.1 - 4e-49 167.4 0.0 5.3e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.7 KFP08263.1 - 0.0057 15.5 0.0 0.025 13.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1501) Phosphodiest PF01663.17 KFP08263.1 - 0.0058 16.0 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PT-TG PF14449.1 KFP08263.1 - 0.064 13.0 0.8 0.16 11.7 0.3 1.7 2 0 0 2 2 2 0 Pre-toxin TG Sulfatase_C PF14707.1 KFP08263.1 - 0.09 13.0 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase L_HGMIC_fpl PF10242.4 KFP08264.1 - 2.5e-64 216.6 8.3 2.9e-64 216.4 5.8 1.0 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 KFP08264.1 - 1.5e-10 41.0 2.0 2.1e-10 40.5 1.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Nucleos_tra2_C PF07662.8 KFP08264.1 - 0.00028 20.4 1.0 0.00028 20.4 0.7 1.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Claudin_3 PF06653.6 KFP08264.1 - 0.0059 16.3 5.8 0.0059 16.3 4.0 1.7 2 0 0 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.15 KFP08264.1 - 0.091 12.4 16.8 0.21 11.2 11.6 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SCAMP PF04144.8 KFP08265.1 - 1.3e-71 240.1 13.2 1.6e-71 239.8 9.2 1.1 1 0 0 1 1 1 1 SCAMP family ABC2_membrane_5 PF13346.1 KFP08265.1 - 0.96 8.7 13.3 1.3 8.2 9.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Lipase_GDSL_2 PF13472.1 KFP08266.1 - 2.8e-07 30.8 0.0 6.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TBCA PF02970.11 KFP08267.1 - 2.7e-23 81.8 7.5 2.9e-23 81.7 5.2 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A Phage_GP20 PF06810.6 KFP08267.1 - 0.0049 16.3 1.5 0.0051 16.2 1.1 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 Pkip-1 PF06878.6 KFP08267.1 - 0.022 14.6 0.8 0.023 14.5 0.6 1.1 1 0 0 1 1 1 0 Pkip-1 protein DUF3841 PF12952.2 KFP08267.1 - 0.043 13.2 0.8 0.051 13.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) DUF745 PF05335.8 KFP08267.1 - 0.081 12.4 2.9 0.093 12.2 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Borrelia_lipo_1 PF05714.6 KFP08267.1 - 0.1 11.6 2.0 0.1 11.6 1.4 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein WD40 PF00400.27 KFP08268.1 - 8.6e-22 76.1 12.7 3e-05 23.7 0.0 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat PDEase_I PF00233.14 KFP08269.1 - 4.6e-62 209.8 2.2 7.4e-62 209.1 1.5 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PAS_9 PF13426.1 KFP08269.1 - 9.3e-17 61.3 0.0 2.9e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KFP08269.1 - 1.5e-13 50.5 0.0 4.3e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold Response_reg PF00072.19 KFP08269.1 - 6.4e-13 48.6 0.0 1.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 KFP08269.1 - 5.1e-06 26.4 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KFP08269.1 - 8e-06 25.8 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 KFP08269.1 - 1.5e-05 24.6 0.0 6.2e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 PAS domain CRF-BP PF05428.6 KFP08270.1 - 6.6e-145 481.7 0.0 7.5e-145 481.5 0.0 1.0 1 0 0 1 1 1 1 Corticotropin-releasing factor binding protein (CRF-BP) Pep_M12B_propep PF01562.14 KFP08270.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide S_100 PF01023.14 KFP08271.1 - 2.9e-19 68.1 0.4 4.7e-19 67.4 0.2 1.4 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_7 PF13499.1 KFP08271.1 - 2.4e-06 27.5 0.6 4.1e-06 26.8 0.4 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP08271.1 - 2.9e-06 26.1 0.4 4e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KFP08271.1 - 0.00082 18.6 1.2 0.017 14.4 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KFP08271.1 - 0.0023 17.6 0.6 0.21 11.5 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KFP08271.1 - 0.079 12.5 2.8 0.054 13.1 0.5 1.9 2 1 0 2 2 2 0 EF-hand domain pair RasGAP PF00616.14 KFP08273.1 - 8.2e-45 152.8 0.0 8.2e-45 152.8 0.0 2.9 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KFP08273.1 - 3.5e-42 143.4 23.5 7.6e-42 142.3 9.3 3.4 3 0 0 3 3 3 2 RasGAP C-terminus IQ PF00612.22 KFP08273.1 - 6.6e-20 68.7 10.4 7.5e-05 22.0 0.0 5.2 5 0 0 5 5 5 4 IQ calmodulin-binding motif CH PF00307.26 KFP08273.1 - 1.4e-11 44.4 0.0 7.6e-11 42.0 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain FAST_1 PF06743.10 KFP08273.1 - 0.017 14.7 0.2 0.94 9.2 0.0 3.1 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 SHD1 PF03983.7 KFP08273.1 - 0.027 14.1 0.2 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 LANC_like PF05147.8 KFP08273.1 - 0.37 9.3 5.5 0.11 11.0 0.0 2.6 3 0 0 3 3 3 0 Lanthionine synthetase C-like protein 7tm_1 PF00001.16 KFP08274.1 - 6.5e-39 133.6 38.1 3.8e-38 131.1 26.4 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PRRSV_2b PF07069.6 KFP08274.1 - 0.0038 17.4 0.7 0.0038 17.4 0.5 3.8 4 1 1 5 5 5 1 Porcine reproductive and respiratory syndrome virus 2b 7TM_GPCR_Srx PF10328.4 KFP08274.1 - 0.0048 16.0 27.6 0.0048 16.0 19.1 2.2 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx MFS_1 PF07690.11 KFP08275.1 - 2.6e-35 121.7 30.6 4.8e-25 88.0 10.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFP08275.1 - 3.5e-32 111.5 18.8 6.7e-29 100.7 2.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_4 PF13599.1 KFP08275.1 - 8.1e-13 47.9 8.9 1.5e-12 47.1 6.1 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 KFP08275.1 - 0.0033 17.2 10.9 0.061 13.2 7.6 2.4 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF1228 PF06779.9 KFP08275.1 - 0.0066 16.4 0.9 0.0066 16.4 0.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Neurensin PF14927.1 KFP08275.1 - 0.06 12.7 0.0 0.22 10.9 0.0 1.9 1 0 0 1 1 1 0 Neurensin MFS_1_like PF12832.2 KFP08275.1 - 0.11 12.2 4.0 0.32 10.8 0.0 3.4 4 0 0 4 4 4 0 MFS_1 like family zf-C4H2 PF10146.4 KFP08277.1 - 0.025 14.5 14.9 0.57 10.1 10.3 2.4 1 1 0 1 1 1 0 Zinc finger-containing protein FliJ PF02050.11 KFP08277.1 - 0.047 13.7 14.4 0.35 10.9 0.1 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein Bacillus_HBL PF05791.6 KFP08277.1 - 0.076 12.3 4.4 0.71 9.2 0.0 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3510 PF12022.3 KFP08277.1 - 0.1 12.7 1.7 0.84 9.7 0.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3510) CENP-F_leu_zip PF10473.4 KFP08277.1 - 0.17 11.7 15.1 1.1 9.1 5.5 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3734 PF12536.3 KFP08277.1 - 0.18 11.9 6.9 1.4 9.0 1.0 2.7 1 1 1 2 2 2 0 Patatin phospholipase Ank_2 PF12796.2 KFP08278.1 - 5.3e-47 158.0 9.3 5.2e-18 65.1 2.1 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFP08278.1 - 2.3e-46 153.3 7.1 2.2e-08 33.5 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KFP08278.1 - 1.1e-35 121.3 7.7 1.3e-11 44.7 0.2 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP08278.1 - 1e-34 115.0 8.8 2.7e-06 27.0 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KFP08278.1 - 2.2e-34 116.7 4.6 1.3e-08 34.8 0.1 6.2 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Death PF00531.17 KFP08278.1 - 1.9e-06 27.5 1.3 3.6e-06 26.6 0.5 1.9 2 0 0 2 2 2 1 Death domain IMS PF00817.15 KFP08279.1 - 5.1e-43 146.4 0.0 2.7e-42 144.0 0.0 2.2 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.3 KFP08279.1 - 8.8e-16 58.0 0.4 3e-15 56.2 0.3 2.0 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFP08279.1 - 7.4e-09 35.1 0.1 1.8e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 KFP08279.1 - 0.0036 17.4 1.8 0.48 10.6 0.0 3.4 3 0 0 3 3 3 1 Helix-hairpin-helix domain zf-C2H2_4 PF13894.1 KFP08279.1 - 0.025 14.9 3.4 0.38 11.1 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Cdd1 PF11731.3 KFP08279.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Pathogenicity locus zf-Di19 PF05605.7 KFP08279.1 - 0.27 11.3 4.4 12 6.0 0.3 2.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.8 KFP08279.1 - 0.61 9.8 5.7 6.3 6.5 0.7 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 KFP08279.1 - 1.8 8.8 6.6 16 5.7 0.1 2.7 2 0 0 2 2 2 0 CHY zinc finger START PF01852.14 KFP08280.1 - 1.9e-29 102.4 0.4 4.3e-29 101.3 0.3 1.5 1 0 0 1 1 1 1 START domain PH PF00169.24 KFP08280.1 - 1.3e-12 47.8 0.6 3.7e-12 46.3 0.4 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFP08280.1 - 9.6e-09 35.2 0.1 3.2e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFP08280.1 - 0.0003 21.0 1.5 0.0029 17.8 1.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Acyl_CoA_thio PF02551.10 KFP08280.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA thioesterase Med18 PF09637.5 KFP08281.1 - 7e-30 104.3 0.0 8.3e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Med18 protein HMG-CoA_red PF00368.13 KFP08282.1 - 4.8e-168 558.6 1.8 6.2e-168 558.2 1.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 KFP08282.1 - 5.2e-17 61.7 3.6 1.1e-16 60.7 2.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFP08282.1 - 4.3e-09 34.9 1.7 6.3e-09 34.3 1.2 1.2 1 0 0 1 1 1 1 Patched family Ank_2 PF12796.2 KFP08283.1 - 8.1e-30 103.0 1.9 2.7e-15 56.4 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFP08283.1 - 4.7e-19 67.1 0.2 1.4e-10 40.3 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFP08283.1 - 1.2e-17 63.5 2.4 3.7e-08 33.3 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP08283.1 - 7.1e-17 61.4 2.3 2.1e-06 28.1 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP08283.1 - 4.7e-13 47.9 0.1 3e-07 30.0 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 KFP08284.1 - 1.2e-24 84.8 0.5 5.9e-07 28.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KFP08284.1 - 2.8e-23 82.0 0.3 1.4e-14 54.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP08284.1 - 2.3e-21 75.7 2.7 4.9e-10 39.6 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP08284.1 - 6.2e-18 64.4 0.4 2e-09 37.4 0.1 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP08284.1 - 4.1e-14 51.2 0.7 0.0033 17.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Baculo_PEP_C PF04513.7 KFP08284.1 - 0.0076 16.0 9.3 0.51 10.1 0.8 2.5 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Sad1_UNC PF07738.8 KFP08285.1 - 2.7e-33 114.6 0.0 3e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal zf-C2H2 PF00096.21 KFP08286.1 - 4.2e-15 55.0 24.4 0.0017 18.5 0.7 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP08286.1 - 9.1e-14 50.9 22.1 6.4e-06 26.2 0.5 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP08286.1 - 2.2e-10 40.1 22.2 0.011 16.0 0.1 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger EpoR_lig-bind PF09067.5 KFP08286.1 - 0.091 12.7 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding zf-met PF12874.2 KFP08286.1 - 2.9 8.2 6.0 5.7 7.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RFX1_trans_act PF04589.8 KFP08287.1 - 1e-54 184.4 32.3 1e-54 184.4 22.4 2.8 3 1 0 3 3 3 1 RFX1 transcription activation region RFX_DNA_binding PF02257.10 KFP08287.1 - 4.5e-39 132.4 0.1 2e-38 130.3 0.0 2.2 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 KFP08287.1 - 0.049 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like CPL PF08144.6 KFP08288.1 - 3.1e-68 228.2 0.2 4.2e-67 224.5 0.0 2.6 2 0 0 2 2 2 1 CPL (NUC119) domain PUF PF00806.14 KFP08288.1 - 0.0048 16.3 2.1 3.6 7.2 0.1 4.5 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DUF3596 PF12167.3 KFP08288.1 - 0.074 12.5 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) Ldl_recept_a PF00057.13 KFP08289.1 - 5e-96 314.2 141.0 1.6e-13 50.2 6.5 8.6 8 0 0 8 8 8 8 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.12 KFP08289.1 - 1.1e-43 147.2 6.7 3.5e-10 40.0 0.0 5.4 5 0 0 5 5 5 5 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFP08289.1 - 7.8e-20 70.7 32.9 4.8e-10 39.3 3.6 6.2 6 2 0 6 6 6 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFP08289.1 - 4.3e-08 32.9 5.5 4.3e-08 32.9 3.8 11.0 6 3 0 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.2 KFP08289.1 - 2.4e-05 23.8 27.7 0.011 15.3 0.5 7.2 5 1 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.22 KFP08289.1 - 5.6e-05 23.0 20.1 0.00046 20.0 4.5 10.1 9 1 0 9 9 9 4 EGF-like domain SGL PF08450.7 KFP08289.1 - 0.0082 15.5 0.1 0.14 11.4 0.0 2.6 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Lipase_GDSL_2 PF13472.1 KFP08290.1 - 0.00013 22.2 0.0 0.00025 21.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4490 PF14892.1 KFP08291.1 - 0.88 9.2 5.4 0.082 12.5 0.3 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4490) DMA PF03474.9 KFP08292.1 - 9.4e-20 70.1 0.0 1.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 DMRTA motif Dmrt1 PF12374.3 KFP08293.1 - 9.2e-29 99.6 19.8 9.3e-23 80.3 4.8 3.0 3 0 0 3 3 3 2 Double-sex mab3 related transcription factor 1 Ustilago_mating PF05722.7 KFP08293.1 - 0.01 15.1 0.8 0.014 14.6 0.5 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Ank PF00023.25 KFP08294.1 - 2e-33 112.4 11.2 5.6e-11 41.6 0.2 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KFP08294.1 - 1.8e-32 111.5 8.4 4.7e-19 68.5 0.4 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP08294.1 - 8.3e-28 95.7 5.6 1.6e-13 50.4 0.1 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFP08294.1 - 8.8e-27 92.9 2.4 1.8e-12 47.3 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFP08294.1 - 7.6e-24 81.4 7.7 8.4e-08 31.7 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat DUF1694 PF07997.6 KFP08294.1 - 0.088 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) KN_motif PF12075.3 KFP08296.1 - 3.6e-22 77.8 0.3 7.9e-22 76.7 0.2 1.6 1 0 0 1 1 1 1 KN motif Phage_GP20 PF06810.6 KFP08296.1 - 0.055 12.9 0.5 0.095 12.1 0.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Ded_cyto PF06920.8 KFP08297.1 - 6.5e-72 240.5 2.3 1.7e-71 239.1 1.6 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 KFP08297.1 - 6.6e-53 179.0 0.4 2e-52 177.5 0.2 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 KFP08297.1 - 6.2e-28 96.5 0.7 8.4e-27 92.8 0.3 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) cobW PF02492.14 KFP08298.1 - 8.2e-42 142.6 0.1 1.1e-41 142.1 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KFP08298.1 - 1.1e-18 66.7 0.0 1.8e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 KFP08298.1 - 1.3e-05 24.7 0.3 0.0003 20.2 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NLE PF08154.7 KFP08298.1 - 0.051 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NLE (NUC135) domain PGM_PMM_III PF02880.11 KFP08299.1 - 3.1e-27 94.8 0.0 5.4e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 KFP08299.1 - 5.4e-14 51.8 0.0 8.4e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFP08299.1 - 2.4e-13 50.3 0.0 5.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFP08299.1 - 0.0018 18.2 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MAP1B_neuraxin PF00414.12 KFP08300.1 - 5.4e-19 66.2 86.9 0.028 13.7 2.7 14.2 13 0 0 13 13 13 12 Neuraxin and MAP1B repeat MRP-S27 PF10037.4 KFP08301.1 - 1.3e-104 350.5 7.8 1.5e-104 350.3 5.4 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.1 KFP08301.1 - 0.0024 17.8 0.1 0.0089 15.9 0.0 2.1 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.2 KFP08301.1 - 0.0052 16.2 0.1 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 PPR repeat TPR_19 PF14559.1 KFP08301.1 - 0.016 15.5 0.0 0.19 12.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 KFP08301.1 - 0.016 15.4 0.0 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PPR PF01535.15 KFP08301.1 - 0.02 14.8 0.0 0.086 12.8 0.0 2.1 1 0 0 1 1 1 0 PPR repeat DUF2997 PF11211.3 KFP08301.1 - 0.25 10.7 0.0 0.25 10.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) PPR_3 PF13812.1 KFP08302.1 - 4.4e-05 23.4 0.3 0.002 18.2 0.0 3.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFP08302.1 - 0.00011 22.0 0.1 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family MRP-S27 PF10037.4 KFP08302.1 - 0.00014 20.9 1.6 0.00028 19.9 1.1 1.7 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR PF01535.15 KFP08302.1 - 0.0002 21.0 0.3 0.0076 16.1 0.1 2.9 2 0 0 2 2 2 1 PPR repeat Apc3 PF12895.2 KFP08302.1 - 0.03 14.4 0.9 0.086 12.9 0.0 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HEAT PF02985.17 KFP08303.1 - 5.8e-36 119.3 11.1 0.0015 18.4 0.0 12.2 12 0 0 12 12 12 7 HEAT repeat HEAT_EZ PF13513.1 KFP08303.1 - 6.1e-31 106.1 1.1 2.2e-10 40.6 0.0 10.7 9 1 2 11 11 11 6 HEAT-like repeat HEAT_2 PF13646.1 KFP08303.1 - 1.2e-25 89.5 0.0 3.2e-06 27.3 0.0 6.7 3 3 5 9 9 9 7 HEAT repeats Arm PF00514.18 KFP08303.1 - 1.9e-16 59.2 2.5 0.011 15.5 0.0 7.8 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 KFP08303.1 - 8.7e-16 58.1 1.2 0.16 12.4 0.0 7.0 5 2 2 7 7 7 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFP08303.1 - 2.4e-14 53.5 4.4 0.00049 20.0 0.1 5.2 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KFP08303.1 - 3.9e-14 52.3 0.5 2.9e-13 49.5 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KFP08303.1 - 1.5e-10 40.0 3.6 0.0032 15.8 0.4 5.0 3 2 1 4 4 4 4 Adaptin N terminal region UNC45-central PF11701.3 KFP08303.1 - 4.2e-06 26.5 3.0 0.018 14.7 0.4 3.8 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 KFP08303.1 - 3.8e-05 23.1 1.0 0.18 11.1 0.0 4.4 4 1 2 6 6 6 1 CLASP N terminal Dopey_N PF04118.9 KFP08303.1 - 9.5e-05 21.3 0.1 0.00032 19.5 0.1 1.9 1 0 0 1 1 1 1 Dopey, N-terminal Proteasom_PSMB PF10508.4 KFP08303.1 - 0.002 16.4 0.5 0.41 8.8 0.0 3.5 3 1 2 5 5 5 2 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 KFP08303.1 - 0.01 14.6 4.0 1.8 7.1 0.1 4.0 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal TAFH PF07531.9 KFP08303.1 - 0.33 10.6 1.7 17 5.1 0.0 4.0 5 0 0 5 5 5 0 NHR1 homology to TAF Pkinase PF00069.20 KFP08304.1 - 5.5e-73 245.3 0.0 7.2e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08304.1 - 6.9e-37 126.9 0.0 8.7e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFP08304.1 - 2.2e-05 23.8 0.1 3.9e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFP08304.1 - 0.00034 19.7 0.0 0.0006 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glycos_trans_3N PF02885.12 KFP08304.1 - 0.038 13.5 0.3 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain RabGAP-TBC PF00566.13 KFP08305.1 - 1.7e-55 187.7 3.6 4e-55 186.5 2.5 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KRAB PF01352.22 KFP08305.1 - 0.01 15.2 0.1 0.068 12.6 0.0 2.4 2 0 0 2 2 2 0 KRAB box DUF1664 PF07889.7 KFP08305.1 - 1.1 9.0 11.9 3.7 7.3 0.5 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KFP08305.1 - 2.1 7.4 5.2 0.45 9.6 1.0 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein CDC37_N PF03234.9 KFP08305.1 - 2.2 8.5 13.5 1 9.6 6.4 2.5 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding EF-hand_7 PF13499.1 KFP08306.1 - 1.3e-12 47.6 1.1 1.5e-10 41.0 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFP08306.1 - 2.3e-09 35.8 7.1 0.00012 21.1 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KFP08306.1 - 3.1e-06 26.6 5.6 0.025 14.4 0.2 3.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KFP08306.1 - 3.3e-06 26.1 6.0 0.0096 15.2 0.5 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KFP08306.1 - 0.00023 20.7 7.6 0.012 15.1 1.6 2.9 2 1 0 2 2 2 2 EF-hand domain pair PMBR PF09373.5 KFP08306.1 - 0.013 15.4 0.0 5.9 7.0 0.0 3.5 4 0 0 4 4 4 0 Pseudomurein-binding repeat DUF3800 PF12686.2 KFP08306.1 - 0.046 13.3 0.1 0.05 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Iso_dh PF00180.15 KFP08307.1 - 1.1e-110 369.8 0.0 1.3e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AMP-binding PF00501.23 KFP08308.1 - 3.9e-82 275.8 0.0 4.8e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DnaJ PF00226.26 KFP08309.1 - 3.6e-26 90.6 2.8 5.9e-26 89.9 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFP08309.1 - 8.8e-22 76.8 0.6 6.6e-17 61.1 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFP08309.1 - 2.3e-13 49.9 20.0 3.9e-13 49.2 13.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFP08309.1 - 0.24 11.0 10.2 2.3 7.9 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 KFP08309.1 - 3.9 7.3 5.7 3.6 7.4 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) WD40 PF00400.27 KFP08310.1 - 5.3e-53 175.1 16.1 1.1e-11 44.1 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 KFP08310.1 - 5.4e-09 36.0 0.0 4.8e-06 26.4 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFP08310.1 - 7.4e-07 27.7 1.5 0.16 10.2 0.0 3.6 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nup160 PF11715.3 KFP08310.1 - 3.7e-05 22.0 0.6 0.17 9.9 0.0 2.8 2 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFP08310.1 - 0.00051 19.5 0.0 0.0016 17.9 0.0 1.7 1 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 KFP08310.1 - 0.0011 18.5 0.2 2 8.1 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat GSDH PF07995.6 KFP08310.1 - 0.0012 18.0 0.0 0.34 9.9 0.0 2.5 1 1 2 3 3 3 2 Glucose / Sorbosone dehydrogenase PQQ PF01011.16 KFP08310.1 - 0.013 15.0 2.6 13 5.5 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat DUF2415 PF10313.4 KFP08310.1 - 0.014 15.0 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Nucleoporin_N PF08801.6 KFP08310.1 - 0.042 12.6 0.4 0.39 9.3 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like DUF3312 PF11768.3 KFP08310.1 - 0.057 11.6 0.0 0.13 10.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) NYD-SP28 PF14772.1 KFP08311.1 - 3.3e-25 88.1 19.0 3.3e-25 88.1 13.1 5.4 4 1 1 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.1 KFP08311.1 - 2.1e-20 72.1 2.2 2.1e-20 72.1 1.6 5.0 5 2 1 6 6 6 1 Sperm tail C-terminal domain Baculo_PEP_N PF04512.7 KFP08311.1 - 0.082 12.8 0.3 14 5.7 0.4 3.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus DUF3584 PF12128.3 KFP08311.1 - 0.12 9.7 60.4 0.19 9.0 41.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DNA_pol_B_thumb PF14791.1 KFP08311.1 - 0.38 10.4 0.1 0.38 10.4 0.0 3.3 3 1 0 3 3 3 0 DNA polymerase beta thumb Stathmin PF00836.14 KFP08313.1 - 3.7e-76 253.4 22.0 4.3e-76 253.2 15.2 1.0 1 0 0 1 1 1 1 Stathmin family CDC37_N PF03234.9 KFP08313.1 - 0.19 12.0 14.6 0.24 11.6 10.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Phage_GPO PF05929.6 KFP08313.1 - 2.3 7.4 8.9 3.1 6.9 6.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.4 KFP08313.1 - 5.1 5.9 18.7 6.9 5.5 13.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Asp-B-Hydro_N PF05279.6 KFP08313.1 - 5.8 6.6 14.4 6.8 6.4 10.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATC_hydrolase PF14196.1 KFP08313.1 - 8.5 6.7 7.8 13 6.2 5.4 1.3 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Fibrinogen_C PF00147.13 KFP08314.1 - 9.6e-45 153.0 0.4 1.1e-44 152.8 0.3 1.0 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Yae1_N PF09811.4 KFP08315.1 - 4.4e-16 58.1 60.1 0.0002 20.7 6.3 6.9 4 2 3 7 7 7 5 Essential protein Yae1, N terminal ACTH_domain PF00976.13 KFP08317.1 - 1.5e-24 85.5 1.9 1.5e-24 85.5 1.3 4.1 4 0 0 4 4 4 2 Corticotropin ACTH domain NPP PF08384.5 KFP08317.1 - 2.5e-22 78.2 1.0 4.5e-22 77.4 0.7 1.4 1 0 0 1 1 1 1 Pro-opiomelanocortin, N-terminal region Op_neuropeptide PF08035.6 KFP08317.1 - 4e-13 48.6 0.1 7.3e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 Opioids neuropeptide CAP_N PF01213.14 KFP08317.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Nucleoplasmin PF03066.10 KFP08317.1 - 0.26 10.7 6.7 0.37 10.2 4.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 KFP08317.1 - 0.3 9.5 11.3 0.4 9.1 7.8 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 KFP08317.1 - 0.81 10.0 6.9 2.2 8.6 4.8 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 KFP08317.1 - 2.4 8.4 7.5 5 7.4 5.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TLV_coat PF00429.14 KFP08318.1 - 2.2e-109 366.4 0.5 2.4e-109 366.3 0.4 1.0 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) SlyX PF04102.7 KFP08318.1 - 0.022 15.1 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 SlyX CBF PF03914.12 KFP08319.1 - 0.059 12.8 2.3 7.2 6.0 0.0 3.5 3 1 0 3 3 3 0 CBF/Mak21 family Ras PF00071.17 KFP08320.1 - 3e-36 124.2 0.0 3.9e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KFP08320.1 - 1.9e-12 46.7 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DnaJ PF00226.26 KFP08320.1 - 3.3e-12 45.9 0.0 5.3e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Miro PF08477.8 KFP08320.1 - 5.5e-11 43.0 0.0 8.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFP08320.1 - 1.1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CENP-O PF09496.5 KFP08321.1 - 5.4e-18 65.0 0.1 5.4e-18 65.0 0.1 2.2 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component BAR_2 PF10455.4 KFP08321.1 - 0.00074 18.5 0.1 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4337 PF14235.1 KFP08321.1 - 0.026 14.3 1.8 0.043 13.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.14 KFP08321.1 - 0.045 11.6 0.2 0.053 11.3 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KFP08321.1 - 0.14 10.5 1.4 0.21 9.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3373 PF11853.3 KFP08321.1 - 0.19 10.2 2.3 0.25 9.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) FlaC_arch PF05377.6 KFP08321.1 - 0.29 11.0 3.4 0.19 11.6 1.0 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 KFP08321.1 - 0.49 9.2 7.0 0.54 9.1 3.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PAS_11 PF14598.1 KFP08322.1 - 9.8e-38 128.5 0.0 1.8e-32 111.6 0.0 2.4 2 0 0 2 2 2 2 PAS domain DUF1518 PF07469.7 KFP08322.1 - 4e-33 113.3 42.5 1.3e-19 70.0 14.7 7.7 8 1 1 9 9 9 2 Domain of unknown function (DUF1518) SRC-1 PF08832.5 KFP08322.1 - 8.6e-27 93.7 2.8 3.8e-26 91.6 1.9 2.3 1 0 0 1 1 1 1 Steroid receptor coactivator Nuc_rec_co-act PF08815.5 KFP08322.1 - 7.1e-22 76.6 1.2 7.1e-22 76.6 0.9 2.3 3 0 0 3 3 3 1 Nuclear receptor coactivator PAS PF00989.19 KFP08322.1 - 3.8e-09 36.3 0.0 3.2e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KFP08322.1 - 4.6e-08 33.3 0.0 3.3e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 KFP08322.1 - 0.00011 22.1 0.0 0.0056 16.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 KFP08322.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold Opiods_neuropep PF01160.13 KFP08324.1 - 1e-12 47.6 1.8 1.6e-12 47.0 1.3 1.3 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide DUF1272 PF06906.6 KFP08324.1 - 0.011 15.6 1.5 0.019 14.8 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Pkinase PF00069.20 KFP08325.1 - 2.5e-50 171.0 0.0 1.1e-49 168.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08325.1 - 1.1e-35 122.9 0.1 3e-26 92.0 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KFP08325.1 - 0.00012 21.2 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFP08325.1 - 0.0016 18.2 0.0 0.02 14.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFP08325.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFP08325.1 - 0.021 14.1 0.0 0.056 12.7 0.0 1.6 2 0 0 2 2 2 0 RIO1 family ABC1 PF03109.11 KFP08325.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 ABC1 family zf-NADH-PPase PF09297.6 KFP08325.1 - 3 7.4 4.9 3.4 7.2 0.3 2.7 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Radical_SAM PF04055.16 KFP08327.1 - 4.5e-19 69.2 2.6 3.7e-18 66.2 0.1 3.2 4 0 0 4 4 4 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KFP08327.1 - 1.1e-10 41.4 0.0 3.5e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFP08327.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein F-box-like PF12937.2 KFP08328.1 - 1.8e-09 37.1 5.7 3.3e-09 36.3 4.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFP08328.1 - 1.8e-08 33.7 2.7 3.7e-08 32.7 1.8 1.5 1 0 0 1 1 1 1 F-box domain HLH PF00010.21 KFP08329.1 - 6.5e-15 54.5 2.0 1.1e-14 53.7 1.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFP08329.1 - 2.1e-08 33.7 0.3 4.1e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 Hairy Orange Translin PF01997.11 KFP08329.1 - 0.002 17.7 1.6 0.0025 17.4 1.1 1.1 1 0 0 1 1 1 1 Translin family HLH PF00010.21 KFP08330.1 - 2.6e-14 52.6 1.7 4.7e-14 51.8 1.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFP08330.1 - 0.00019 21.0 0.1 0.00036 20.1 0.1 1.4 1 0 0 1 1 1 1 Hairy Orange DUF1474 PF07342.6 KFP08330.1 - 0.087 13.0 0.2 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1474) RNA_pol_Rpb4 PF03874.11 KFP08330.1 - 0.11 12.5 1.6 0.15 12.0 1.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 Lzipper-MIP1 PF14389.1 KFP08330.1 - 0.95 9.6 7.2 1.2 9.3 0.7 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 HLH PF00010.21 KFP08331.1 - 9.6e-15 54.0 2.9 1.7e-14 53.2 2.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hairy_orange PF07527.8 KFP08331.1 - 3.4e-08 33.0 0.3 5.6e-08 32.3 0.2 1.3 1 0 0 1 1 1 1 Hairy Orange Fumble PF03630.9 KFP08332.1 - 2.8e-138 460.4 4.0 3.9e-138 459.9 2.8 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.14 KFP08332.1 - 9.3e-57 192.4 0.0 1.4e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Lig_chan PF00060.21 KFP08333.1 - 1.5e-40 138.2 0.2 2.9e-40 137.3 0.1 1.5 2 0 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.15 KFP08333.1 - 4.7e-22 78.3 0.0 6.6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.4 KFP08333.1 - 1.9e-20 72.5 0.0 3.8e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF1795 PF08786.6 KFP08333.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) Ion_trans_2 PF07885.11 KFP08333.1 - 5.3 6.8 7.6 0.73 9.5 1.1 2.8 3 1 0 3 3 3 0 Ion channel PI-PLC-X PF00388.14 KFP08334.1 - 5.8e-65 217.1 0.1 1.3e-64 215.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFP08334.1 - 2.8e-44 149.8 0.9 9.2e-44 148.2 0.6 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFP08334.1 - 7.2e-26 90.0 0.8 5.9e-25 87.1 0.1 2.6 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KFP08334.1 - 6.1e-16 58.0 0.0 1.5e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KFP08334.1 - 7.2e-13 48.4 4.3 1.1e-11 44.6 0.6 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP08334.1 - 3.8e-09 35.1 4.1 0.00039 19.5 0.0 3.2 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP08334.1 - 1e-06 28.1 3.0 0.055 13.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_10 PF14788.1 KFP08334.1 - 1.8e-06 27.5 1.3 8.8e-06 25.2 0.2 2.4 1 1 1 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFP08334.1 - 9e-06 25.2 6.0 0.0015 18.0 0.6 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KFP08334.1 - 2.4e-05 23.4 1.5 0.0015 17.7 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 KFP08334.1 - 0.00085 19.0 0.5 0.0035 17.0 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Mcp5_PH PF12814.2 KFP08334.1 - 0.0084 16.0 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology SPARC_Ca_bdg PF10591.4 KFP08334.1 - 0.017 15.1 0.1 0.05 13.6 0.1 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Pex2_Pex12 PF04757.9 KFP08335.1 - 3.9e-35 121.3 4.6 5e-35 120.9 3.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KFP08335.1 - 4.3e-10 39.2 14.5 8.6e-10 38.2 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP08335.1 - 9.5e-10 38.3 12.7 1.8e-09 37.4 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP08335.1 - 6.3e-09 35.3 11.9 1.1e-08 34.5 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP08335.1 - 7.7e-07 28.7 11.0 1.4e-06 27.9 7.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFP08335.1 - 8.2e-07 28.5 12.6 1.6e-06 27.6 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP08335.1 - 0.00013 21.9 9.6 0.00027 20.9 6.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFP08335.1 - 0.0014 18.3 5.0 0.0017 18.0 2.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger DUF3290 PF11694.3 KFP08335.1 - 0.0017 18.0 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) zf-C3HC4_4 PF15227.1 KFP08335.1 - 0.004 17.0 10.4 0.013 15.3 7.3 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFP08335.1 - 0.0071 16.1 3.9 0.015 15.1 2.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFP08335.1 - 0.087 12.6 5.4 0.16 11.8 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFP08335.1 - 0.087 12.4 10.3 0.16 11.5 7.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KFP08335.1 - 0.28 10.7 10.9 0.68 9.5 7.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Rer1 PF03248.8 KFP08336.1 - 9.2e-79 263.1 8.0 1.1e-78 262.9 5.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 KFP08336.1 - 0.85 8.8 4.6 0.097 11.8 0.3 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) c-SKI_SMAD_bind PF08782.5 KFP08337.1 - 8.4e-51 170.0 0.9 8.4e-51 170.0 0.6 2.3 2 0 0 2 2 2 1 c-SKI Smad4 binding domain Ski_Sno PF02437.12 KFP08337.1 - 1.4e-44 150.3 0.3 2.9e-44 149.2 0.2 1.5 1 0 0 1 1 1 1 SKI/SNO/DAC family Kinetocho_Slk19 PF12709.2 KFP08337.1 - 3.8 7.6 22.1 0.12 12.4 1.0 4.5 3 1 2 5 5 5 0 Central kinetochore-associated Pkinase PF00069.20 KFP08338.1 - 1.4e-61 207.9 0.0 1.9e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08338.1 - 1.9e-33 115.6 0.0 3.6e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.19 KFP08338.1 - 6.8e-15 54.5 0.1 1.6e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.17 KFP08338.1 - 3.5e-14 52.2 6.6 7.7e-14 51.1 4.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFP08338.1 - 9e-07 29.3 0.7 1.8e-06 28.3 0.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFP08338.1 - 1.1e-05 24.5 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFP08338.1 - 0.012 14.6 0.0 0.031 13.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_3 PF07649.7 KFP08338.1 - 0.17 11.9 1.3 0.54 10.3 0.9 1.9 1 0 0 1 1 1 0 C1-like domain Neur_chan_LBD PF02931.18 KFP08339.1 - 5.8e-51 172.7 0.1 9.5e-51 172.0 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.11 KFP08339.1 - 3.7e-41 141.5 4.5 8.8e-36 123.9 1.4 2.4 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region BRF1 PF07741.8 KFP08339.1 - 0.066 13.4 0.2 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PapD-like PF14874.1 KFP08340.1 - 5.9e-07 29.3 0.0 0.018 14.9 0.0 2.8 3 0 0 3 3 3 2 Flagellar-associated PapD-like DUF1034 PF06280.7 KFP08340.1 - 0.048 14.0 0.2 13 6.1 0.0 2.7 3 0 0 3 3 3 0 Fn3-like domain (DUF1034) TMEM52 PF14979.1 KFP08341.1 - 6.5e-24 84.5 3.1 7e-24 84.4 2.1 1.0 1 0 0 1 1 1 1 Transmembrane 52 Corona_S2 PF01601.11 KFP08341.1 - 0.97 7.4 4.8 1 7.3 3.3 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein NAD_kinase PF01513.16 KFP08342.1 - 6.5e-63 212.1 0.1 9.2e-63 211.6 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Guanylate_cyc PF00211.15 KFP08343.1 - 0.12 11.6 0.1 0.36 10.1 0.0 1.7 1 1 1 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain TPT PF03151.11 KFP08344.1 - 7.8e-33 113.2 8.7 7.8e-33 113.2 6.0 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFP08344.1 - 5.9e-15 55.4 26.8 3.6e-08 33.4 5.2 2.6 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 KFP08344.1 - 1e-08 34.4 25.0 2.5e-08 33.1 17.3 1.6 1 1 0 1 1 1 1 UAA transporter family DUF2611 PF11022.3 KFP08344.1 - 0.097 12.7 0.7 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Pkinase PF00069.20 KFP08345.1 - 2.6e-68 230.0 0.5 8.9e-68 228.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08345.1 - 2.3e-30 105.5 0.3 7.3e-30 103.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP08345.1 - 1.8e-05 23.8 3.0 0.00016 20.7 0.0 2.7 2 1 1 3 3 3 2 Kinase-like Peptidase_M10 PF00413.19 KFP08346.1 - 4.4e-38 130.4 0.2 6e-38 129.9 0.1 1.2 1 0 0 1 1 1 1 Matrixin ShK PF01549.19 KFP08346.1 - 5.3e-09 36.2 6.8 8.6e-09 35.6 4.7 1.4 1 0 0 1 1 1 1 ShK domain-like Ig_2 PF13895.1 KFP08346.1 - 3.8e-06 26.9 0.0 7.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.12 KFP08346.1 - 0.00033 20.5 0.5 0.0036 17.1 0.3 2.2 1 1 0 1 1 1 1 Immunoglobulin V-set domain Reprolysin_4 PF13583.1 KFP08346.1 - 0.015 14.8 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like I-set PF07679.11 KFP08346.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain Reprolysin_5 PF13688.1 KFP08346.1 - 0.02 14.8 1.3 0.11 12.4 1.1 1.8 1 1 1 2 2 2 0 Metallo-peptidase family M12 DUF3152 PF11350.3 KFP08346.1 - 0.03 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_3 PF13582.1 KFP08346.1 - 0.033 14.7 1.9 0.053 14.0 1.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFP08346.1 - 0.043 13.8 1.3 0.072 13.1 0.9 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Bud13 PF09736.4 KFP08346.1 - 0.076 13.2 0.1 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Peptidase_M66 PF10462.4 KFP08346.1 - 0.09 11.6 0.2 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 KFP08346.1 - 0.18 11.1 3.2 0.59 9.4 1.1 2.5 3 1 1 4 4 4 0 Astacin (Peptidase family M12A) DUF724 PF05266.9 KFP08347.1 - 3.1 7.3 32.4 0.31 10.6 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Ssu72 PF04722.8 KFP08349.1 - 2.9e-73 245.3 0.1 3.2e-73 245.2 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein TPR_MLP1_2 PF07926.7 KFP08349.1 - 0.073 12.8 0.5 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMEM240 PF15207.1 KFP08350.1 - 5.2e-63 211.9 1.7 5.9e-63 211.7 1.2 1.0 1 0 0 1 1 1 1 TMEM240 family DUF3523 PF12037.3 KFP08351.1 - 4.2e-79 265.4 30.8 4.1e-79 265.4 21.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.24 KFP08351.1 - 2e-21 76.5 0.0 6.2e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFP08351.1 - 8e-07 29.8 1.5 4e-06 27.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFP08351.1 - 0.00014 21.0 0.2 0.0037 16.4 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KFP08351.1 - 0.00042 20.4 9.2 0.044 13.9 0.0 3.5 2 2 1 3 3 2 2 AAA domain AAA_25 PF13481.1 KFP08351.1 - 0.00067 19.1 0.0 0.00067 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFP08351.1 - 0.0015 18.3 0.0 0.0015 18.3 0.0 2.7 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KFP08351.1 - 0.0016 17.8 0.1 0.014 14.7 0.0 2.6 2 1 1 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.7 KFP08351.1 - 0.0023 16.9 0.0 0.0023 16.9 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zot PF05707.7 KFP08351.1 - 0.0029 17.1 6.2 0.01 15.2 0.0 3.0 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) KaiC PF06745.8 KFP08351.1 - 0.0035 16.4 2.1 0.0041 16.2 0.0 2.1 2 1 0 2 2 2 1 KaiC Ycf1 PF05758.7 KFP08351.1 - 0.007 14.1 1.9 0.0068 14.1 1.3 1.2 1 0 0 1 1 1 1 Ycf1 AAA_5 PF07728.9 KFP08351.1 - 0.0078 15.9 4.8 0.033 13.8 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFP08351.1 - 0.015 15.0 0.0 0.058 13.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 KFP08351.1 - 0.025 14.1 0.1 0.025 14.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFP08351.1 - 0.03 14.4 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KFP08351.1 - 0.036 13.7 0.3 0.34 10.5 0.0 2.6 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.1 KFP08351.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.8 2 2 0 3 3 2 0 AAA ATPase domain AAA_18 PF13238.1 KFP08351.1 - 0.21 11.8 2.5 0.5 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFP08351.1 - 0.3 11.0 15.6 0.42 10.5 0.0 3.4 2 2 1 3 3 3 0 AAA domain AAA_11 PF13086.1 KFP08351.1 - 1.1 8.8 0.0 1.1 8.8 0.0 2.9 2 1 0 2 2 1 0 AAA domain Borrelia_P83 PF05262.6 KFP08351.1 - 1.2 7.3 19.8 2 6.6 13.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.11 KFP08351.1 - 1.2 7.5 2.6 1.5 7.3 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_10 PF12846.2 KFP08351.1 - 2.1 7.7 5.8 1.4 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain VWA PF00092.23 KFP08352.1 - 8.4e-37 126.6 0.0 1.4e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain fn3 PF00041.16 KFP08352.1 - 4e-20 71.7 1.6 1.6e-09 37.7 0.2 2.3 2 0 0 2 2 2 2 Fibronectin type III domain VWA_2 PF13519.1 KFP08352.1 - 7.2e-15 55.5 0.0 1.1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Interfer-bind PF09294.5 KFP08352.1 - 0.00018 21.5 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 2 Interferon-alpha/beta receptor, fibronectin type III VWA_CoxE PF05762.9 KFP08352.1 - 0.0054 15.8 0.0 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Big_5 PF13205.1 KFP08352.1 - 0.056 14.0 0.5 2.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Bacterial Ig-like domain DUF2852 PF11014.3 KFP08353.1 - 0.053 13.4 1.7 0.061 13.2 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF3661 PF12400.3 KFP08353.1 - 1.7 8.7 7.8 1.2 9.2 3.5 1.9 1 1 1 2 2 2 0 Vaculolar membrane protein Ribosomal_L20 PF00453.13 KFP08354.1 - 1.1e-33 115.3 4.0 1.4e-33 115.0 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Cyclin_N PF00134.18 KFP08355.1 - 3.3e-13 49.2 0.9 1.1e-07 31.4 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP08355.1 - 8.8e-06 25.6 0.1 8.8e-06 25.6 0.1 2.6 3 0 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.14 KFP08355.1 - 6.6e-05 22.6 0.3 0.11 12.3 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat E2F_TDP PF02319.15 KFP08355.1 - 0.044 13.3 0.2 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain DUF2779 PF11074.3 KFP08355.1 - 0.065 13.2 1.7 3.8 7.5 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) adh_short PF00106.20 KFP08356.1 - 7.2e-19 68.3 0.0 1.1e-18 67.7 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFP08356.1 - 5.6e-10 39.3 0.0 7.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFP08356.1 - 1.8e-07 31.0 0.2 2.5e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFP08356.1 - 0.014 15.1 0.3 0.79 9.5 0.1 2.9 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 KFP08356.1 - 0.046 14.1 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 KFP08356.1 - 0.051 13.1 0.0 0.17 11.4 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PCI PF01399.22 KFP08356.1 - 0.14 12.5 0.9 0.33 11.2 0.3 1.7 1 1 1 2 2 2 0 PCI domain DUF1713 PF08213.6 KFP08357.1 - 7.9e-12 44.5 19.7 7.9e-12 44.5 13.6 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) ScpA_ScpB PF02616.9 KFP08357.1 - 0.2 11.1 3.1 0.29 10.7 2.1 1.1 1 0 0 1 1 1 0 ScpA/B protein V-set PF07686.12 KFP08358.1 - 6.1e-22 77.6 0.1 2.3e-11 43.5 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin V-set domain I-set PF07679.11 KFP08358.1 - 3.8e-08 33.0 0.0 0.011 15.5 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.1 KFP08358.1 - 1.3e-07 31.6 0.0 0.007 16.4 0.0 2.7 2 2 0 2 2 2 2 Immunoglobulin domain ig PF00047.20 KFP08358.1 - 1.2e-06 28.4 0.0 0.053 13.6 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.1 KFP08358.1 - 7.5e-06 26.3 1.5 0.15 12.5 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain FixQ PF05545.6 KFP08358.1 - 0.0043 16.6 0.5 0.0079 15.8 0.4 1.4 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Receptor_2B4 PF11465.3 KFP08358.1 - 0.011 15.6 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 V-set_CD47 PF08204.6 KFP08358.1 - 0.011 15.4 0.1 0.58 9.9 0.0 2.5 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain TMEM154 PF15102.1 KFP08358.1 - 0.031 13.9 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF347 PF03988.7 KFP08358.1 - 0.078 12.8 0.6 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Dsh_C PF12316.3 KFP08359.1 - 2.1e-80 269.6 31.5 2.1e-80 269.6 21.8 2.9 2 1 1 3 3 3 1 Segment polarity protein dishevelled (Dsh) C terminal Dishevelled PF02377.10 KFP08359.1 - 9.7e-24 83.3 11.0 9.7e-24 83.3 7.6 3.4 4 0 0 4 4 4 1 Dishevelled specific domain PDZ PF00595.19 KFP08359.1 - 3.6e-21 75.1 0.3 5.9e-21 74.4 0.2 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DEP PF00610.16 KFP08359.1 - 1.1e-16 60.2 0.1 2.4e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_2 PF13180.1 KFP08359.1 - 0.0016 18.2 0.2 0.0032 17.3 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Shufflon_N PF04917.7 KFP08359.1 - 0.032 13.3 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region SpoIIIAH PF12685.2 KFP08359.1 - 1.1 8.6 5.4 0.21 11.0 0.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein GLTP PF08718.6 KFP08360.1 - 3.1e-40 137.6 0.0 4e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PseudoU_synth_1 PF01416.15 KFP08361.1 - 3.2e-29 101.4 0.0 1.8e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase ArfGap PF01412.13 KFP08362.1 - 2e-41 140.4 0.6 2e-41 140.4 0.4 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 KFP08362.1 - 1.3e-21 76.7 1.1 1.7e-15 57.0 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFP08362.1 - 7.1e-15 55.0 0.8 5.8e-06 26.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFP08362.1 - 8.1e-15 53.7 1.8 2.2e-05 24.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.24 KFP08362.1 - 2e-13 50.3 0.3 5.4e-13 49.0 0.2 1.8 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.1 KFP08362.1 - 4e-13 49.1 1.2 2.7e-09 36.9 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH_11 PF15413.1 KFP08362.1 - 3e-07 30.6 2.6 3e-05 24.2 1.2 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain Ank_3 PF13606.1 KFP08362.1 - 7.9e-07 28.7 1.5 0.22 11.8 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Hepsin-SRCR PF09272.5 KFP08362.1 - 0.044 14.0 0.2 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Hepsin, SRCR UQ_con PF00179.21 KFP08363.1 - 2.3e-27 95.1 0.0 3.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Neisseria_TspB PF05616.8 KFP08363.1 - 0.051 11.9 0.0 0.071 11.4 0.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein C1q PF00386.16 KFP08364.1 - 9.9e-07 28.8 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 C1q domain Collagen PF01391.13 KFP08364.1 - 0.0024 17.3 4.3 0.0037 16.7 3.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.13 KFP08364.1 - 0.0025 17.3 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 TNF(Tumour Necrosis Factor) family Peptidase_M13_N PF05649.8 KFP08365.1 - 5.4e-134 447.1 7.1 5.4e-134 447.1 4.9 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 KFP08365.1 - 2.8e-66 222.6 0.1 4.9e-66 221.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.13 KFP08365.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M48 TPR_11 PF13414.1 KFP08366.1 - 3.2e-34 116.3 19.7 1.8e-11 43.5 0.2 7.6 7 1 1 8 8 8 7 TPR repeat TPR_2 PF07719.12 KFP08366.1 - 1.1e-23 81.1 16.6 0.022 14.6 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.23 KFP08366.1 - 5.1e-18 63.8 24.8 0.015 14.8 0.0 10.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFP08366.1 - 9.8e-15 54.7 24.9 1.9e-05 25.1 0.0 6.2 7 1 1 8 8 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFP08366.1 - 1.4e-13 50.4 9.5 0.00012 21.8 0.0 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFP08366.1 - 1.5e-12 47.6 15.1 0.0026 18.0 0.3 7.8 6 3 2 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 KFP08366.1 - 4.3e-11 42.8 24.7 0.013 15.6 0.1 7.1 5 3 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFP08366.1 - 7.2e-11 41.0 6.2 1.6 8.6 0.0 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFP08366.1 - 4e-10 39.4 20.6 0.12 12.3 1.2 7.9 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFP08366.1 - 4.7e-10 39.2 16.8 0.025 15.1 0.3 8.1 7 3 3 10 10 8 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFP08366.1 - 2.4e-06 26.8 5.8 0.01 14.9 0.3 4.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFP08366.1 - 2.5e-06 27.5 15.5 0.0081 16.2 0.1 5.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFP08366.1 - 5.4e-06 26.5 2.2 12 6.5 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFP08366.1 - 6.5e-06 25.9 6.7 0.081 13.1 0.0 7.3 8 1 0 8 8 8 1 Tetratricopeptide repeat SNAP PF14938.1 KFP08366.1 - 0.0024 17.1 1.5 0.0024 17.1 1.0 3.8 5 0 0 5 5 5 1 Soluble NSF attachment protein, SNAP TPR_5 PF12688.2 KFP08366.1 - 0.027 14.5 5.7 0.24 11.4 0.1 4.4 4 2 1 5 5 5 0 Tetratrico peptide repeat TPR_4 PF07721.9 KFP08366.1 - 0.17 12.4 0.0 0.17 12.4 0.0 4.5 6 0 0 6 6 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP08366.1 - 1.5 8.8 11.7 6.5 6.8 0.1 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 KFP08368.1 - 1.3e-48 160.4 90.0 7.8e-07 29.0 0.8 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP08368.1 - 2.2e-29 100.2 82.4 2.9e-09 36.7 0.9 12.1 12 1 0 12 12 12 7 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP08368.1 - 1.7e-27 93.7 79.6 0.00028 21.0 0.8 10.5 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP08368.1 - 7.7e-13 48.1 55.9 0.031 14.4 0.1 10.3 10 0 0 10 10 10 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP08368.1 - 1.7e-12 46.7 70.4 0.014 15.2 0.3 10.4 10 0 0 10 10 10 8 C2H2-type zinc finger zf-BED PF02892.10 KFP08368.1 - 1.4e-05 24.7 7.7 7.2e-05 22.4 0.6 8.7 3 3 5 8 8 8 3 BED zinc finger zf-met PF12874.2 KFP08368.1 - 0.019 15.1 50.7 0.38 11.0 0.2 9.4 9 0 0 9 9 9 0 Zinc-finger of C2H2 type GAGA PF09237.6 KFP08368.1 - 3.5 7.2 26.4 1.7 8.3 0.3 5.9 4 1 2 6 6 6 0 GAGA factor RhoGEF PF00621.15 KFP08369.1 - 8e-37 126.8 2.3 1.1e-36 126.3 1.6 1.2 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.1 KFP08369.1 - 2.7e-12 46.0 0.1 6.1e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP08369.1 - 1.3e-08 34.0 1.0 2.1e-08 33.3 0.1 1.8 2 0 0 2 2 2 1 SH3 domain PH PF00169.24 KFP08369.1 - 1.5e-07 31.5 0.0 3.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 KFP08369.1 - 2.6e-07 30.0 0.0 6e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain YtxC PF08812.6 KFP08369.1 - 0.073 12.5 2.3 0.46 9.9 1.6 2.0 1 1 0 1 1 1 0 YtxC-like family hSac2 PF12456.3 KFP08370.1 - 3.7e-33 113.3 0.2 5.3e-33 112.8 0.1 1.2 1 0 0 1 1 1 1 Inositol phosphatase WD40 PF00400.27 KFP08371.1 - 1.3e-10 40.6 8.1 0.00011 21.9 0.0 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.6 KFP08371.1 - 7.6e-09 35.5 0.1 0.016 14.9 0.0 3.9 2 2 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFP08371.1 - 0.0012 16.8 2.7 0.54 8.0 0.1 3.0 2 1 1 4 4 4 2 IKI3 family P53 PF00870.13 KFP08372.1 - 7.3e-109 361.8 0.2 1.2e-108 361.0 0.1 1.3 1 0 0 1 1 1 1 P53 DNA-binding domain P53_tetramer PF07710.6 KFP08372.1 - 1.7e-18 65.4 0.5 4e-18 64.2 0.3 1.7 1 0 0 1 1 1 1 P53 tetramerisation motif SAM_2 PF07647.12 KFP08372.1 - 1.3e-08 34.5 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFP08372.1 - 0.00086 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IncA PF04156.9 KFP08373.1 - 0.0024 17.5 33.8 0.021 14.4 12.0 2.3 1 1 1 2 2 2 2 IncA protein Reo_sigmaC PF04582.7 KFP08373.1 - 0.016 14.3 4.7 0.03 13.5 3.3 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein MMS19_C PF12460.3 KFP08373.1 - 0.025 13.3 6.4 0.027 13.1 4.1 1.3 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal CENP-Q PF13094.1 KFP08373.1 - 0.026 14.5 25.0 0.2 11.6 8.5 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LMWPc PF01451.16 KFP08373.1 - 0.042 14.1 5.6 0.053 13.8 2.2 2.0 1 1 1 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase NEMO PF11577.3 KFP08373.1 - 0.062 13.0 1.7 0.062 13.0 1.2 3.9 4 0 0 4 4 4 0 NF-kappa-B essential modulator NEMO Prominin PF05478.6 KFP08373.1 - 0.08 10.4 12.2 0.11 10.0 8.4 1.1 1 0 0 1 1 1 0 Prominin SlyX PF04102.7 KFP08373.1 - 0.1 12.9 26.9 0.1 12.9 8.5 3.4 2 1 0 2 2 2 0 SlyX TBPIP PF07106.8 KFP08373.1 - 0.2 11.2 25.9 2.8 7.4 7.9 2.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 KFP08373.1 - 0.34 9.2 22.4 0.14 10.5 8.1 2.0 1 1 1 2 2 2 0 AAA domain Fez1 PF06818.10 KFP08373.1 - 0.39 10.7 23.8 2.4 8.1 15.6 2.2 1 1 1 2 2 2 0 Fez1 PspA_IM30 PF04012.7 KFP08373.1 - 1.4 8.2 32.6 1.1 8.6 12.8 2.1 1 1 1 2 2 2 0 PspA/IM30 family USP8_interact PF08941.5 KFP08373.1 - 2.6 7.3 12.0 1 8.6 2.8 2.3 2 0 0 2 2 2 0 USP8 interacting DivIC PF04977.10 KFP08373.1 - 2.6 7.5 28.4 1.8 8.1 4.0 3.6 1 1 2 3 3 3 0 Septum formation initiator ADIP PF11559.3 KFP08373.1 - 3.7 7.4 30.5 2.9 7.7 4.8 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 KFP08373.1 - 4.7 6.9 27.7 2 8.2 4.5 2.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KFP08373.1 - 4.8 5.7 24.7 4 6.0 16.5 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein AA_kinase PF00696.23 KFP08373.1 - 4.8 6.6 8.9 18 4.7 6.2 1.9 1 1 0 1 1 1 0 Amino acid kinase family Lebercilin PF15619.1 KFP08373.1 - 6.8 6.0 32.1 2.6 7.4 19.1 2.2 2 1 0 2 2 1 0 Ciliary protein causing Leber congenital amaurosis disease IZUMO PF15005.1 KFP08373.1 - 7.2 6.6 13.0 0.42 10.6 2.8 2.5 1 1 1 2 2 2 0 Izumo sperm-egg fusion DUF1664 PF07889.7 KFP08373.1 - 7.4 6.3 18.9 0.89 9.3 4.6 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 KFP08373.1 - 7.5 6.3 25.7 15 5.3 7.2 3.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 KFP08373.1 - 7.8 5.3 26.8 19 4.0 18.3 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3847 PF12958.2 KFP08373.1 - 8.1 6.2 30.5 2.4 7.9 4.6 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) Cluap1 PF10234.4 KFP08373.1 - 8.3 5.5 28.9 1.6 7.8 4.1 2.3 2 1 1 3 3 3 0 Clusterin-associated protein-1 B3_4 PF03483.12 KFP08374.1 - 8.5e-10 38.3 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain LRR_4 PF12799.2 KFP08374.1 - 3e-05 23.5 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFP08374.1 - 0.0029 17.3 0.1 0.021 14.5 0.0 2.5 3 0 0 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 KFP08374.1 - 0.11 12.7 0.2 4.3 7.9 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat UVR PF02151.14 KFP08375.1 - 0.0016 17.8 15.8 0.028 13.9 2.3 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif CLASP_N PF12348.3 KFP08375.1 - 0.015 14.6 0.2 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 CLASP N terminal HEAT PF02985.17 KFP08375.1 - 0.12 12.4 0.1 45 4.5 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat DFF40 PF09230.5 KFP08376.1 - 4e-92 307.7 4.7 4.5e-92 307.5 3.2 1.0 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa AJAP1_PANP_C PF15298.1 KFP08378.1 - 5.2e-41 140.8 0.9 5.9e-41 140.6 0.6 1.0 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Aldo_ket_red PF00248.16 KFP08380.1 - 2e-32 112.1 0.0 2.2e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UDG PF03167.14 KFP08380.1 - 0.048 13.1 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Aldo_ket_red PF00248.16 KFP08381.1 - 2.2e-15 56.2 0.0 2.4e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MRF_C1 PF13887.1 KFP08381.1 - 0.0093 14.9 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 DUF4332 PF14229.1 KFP08381.1 - 0.045 13.7 0.1 0.057 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) SMI1_KNR4 PF09346.5 KFP08381.1 - 0.052 13.5 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) CHDCT2 PF08074.6 KFP08382.1 - 9.4e-92 305.4 0.2 1.9e-91 304.4 0.1 1.6 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain SNF2_N PF00176.18 KFP08382.1 - 4.2e-67 226.0 0.1 4.2e-67 226.0 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF1086 PF06461.6 KFP08382.1 - 8.1e-59 197.5 0.0 2.3e-58 196.1 0.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) CHDNT PF08073.7 KFP08382.1 - 4.7e-30 103.0 0.4 1e-29 101.9 0.3 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1087 PF06465.8 KFP08382.1 - 8.3e-27 92.9 6.5 4.2e-26 90.6 4.5 2.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) Chromo PF00385.19 KFP08382.1 - 1.7e-18 66.0 4.1 7.8e-12 44.6 0.3 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFP08382.1 - 1.3e-16 60.2 0.0 3.5e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 KFP08382.1 - 1.8e-11 43.5 7.2 3.9e-11 42.4 5.0 1.6 1 0 0 1 1 1 1 PHD-finger ResIII PF04851.10 KFP08382.1 - 3.1e-05 23.8 2.1 5e-05 23.2 0.0 2.5 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit zf-HC5HC2H PF13771.1 KFP08382.1 - 0.0096 16.0 0.5 0.025 14.7 0.4 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain AAA_22 PF13401.1 KFP08382.1 - 0.028 14.5 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Prok-RING_1 PF14446.1 KFP08382.1 - 0.3 10.8 3.5 0.63 9.8 2.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Ribosomal_L22e PF01776.12 KFP08383.1 - 1.6e-54 182.6 2.2 1.9e-54 182.4 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family zf-B_box PF00643.19 KFP08384.1 - 2.8e-07 30.3 8.0 2.8e-07 30.3 5.5 4.1 4 0 0 4 4 3 2 B-box zinc finger zf-C3HC4 PF00097.20 KFP08384.1 - 2.1e-05 24.1 10.1 2.1e-05 24.1 7.0 4.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP08384.1 - 6.4e-05 22.6 11.0 6.4e-05 22.6 7.6 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP08384.1 - 0.00022 20.9 11.3 0.00022 20.9 7.8 3.5 3 0 0 3 3 3 1 Ring finger domain MAD PF05557.8 KFP08384.1 - 0.00033 18.8 13.5 0.00039 18.6 0.3 2.1 2 0 0 2 2 2 1 Mitotic checkpoint protein Exonuc_VII_L PF02601.10 KFP08384.1 - 0.00081 18.6 3.3 0.00081 18.6 2.3 2.1 2 0 0 2 2 2 1 Exonuclease VII, large subunit AIP3 PF03915.8 KFP08384.1 - 0.0015 17.5 10.4 0.012 14.6 0.8 2.1 2 0 0 2 2 2 2 Actin interacting protein 3 zf-C3HC4_3 PF13920.1 KFP08384.1 - 0.0033 17.0 10.0 0.0033 17.0 6.9 4.0 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) IL10 PF00726.12 KFP08384.1 - 0.0045 16.2 1.2 0.0045 16.2 0.8 2.7 2 2 0 2 2 2 1 Interleukin 10 zf-C3HC4_4 PF15227.1 KFP08384.1 - 0.022 14.6 12.0 0.022 14.6 8.3 3.9 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-CHC2 PF01807.15 KFP08384.1 - 0.029 13.9 2.0 0.047 13.2 0.2 2.3 2 0 0 2 2 2 0 CHC2 zinc finger OmpH PF03938.9 KFP08384.1 - 0.052 13.4 14.0 0.06 13.2 2.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Thioredoxin_7 PF13899.1 KFP08384.1 - 0.067 13.2 0.1 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like DUF3400 PF11880.3 KFP08384.1 - 0.069 12.3 0.3 0.13 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) zf-RING_UBOX PF13445.1 KFP08384.1 - 0.21 11.3 9.2 0.098 12.3 3.7 2.5 2 0 0 2 2 2 0 RING-type zinc-finger DivIVA PF05103.8 KFP08384.1 - 0.53 10.3 18.3 0.59 10.1 4.5 2.9 2 1 0 2 2 2 0 DivIVA protein V-SNARE PF05008.10 KFP08384.1 - 1.8 8.7 12.4 2.8 8.1 3.0 3.5 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.7 KFP08384.1 - 2 8.2 8.1 0.5 10.1 0.7 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KFP08384.1 - 4.4 7.4 17.9 0.57 10.2 1.8 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3708 PF12501.3 KFP08384.1 - 5.7 6.7 7.0 2.9 7.6 1.3 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter ICMT PF04140.9 KFP08385.1 - 1.6e-34 117.9 0.1 2.6e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KFP08385.1 - 6.1e-10 39.1 0.6 1e-09 38.4 0.4 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 KFP08385.1 - 0.017 14.4 0.2 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) 4HBT PF03061.17 KFP08386.1 - 4.7e-33 113.1 1.9 3.8e-16 58.9 0.1 2.2 2 0 0 2 2 2 2 Thioesterase superfamily tRNA_anti-codon PF01336.20 KFP08386.1 - 0.00011 22.0 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CARDB PF07705.6 KFP08386.1 - 0.059 13.4 0.2 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 CARDB IMCp PF12314.3 KFP08386.1 - 1.8 8.7 7.8 3.1 8.0 2.7 2.8 2 1 1 3 3 3 0 Inner membrane complex protein IPPT PF01715.12 KFP08387.1 - 0.068 12.1 0.0 0.074 12.0 0.0 1.0 1 0 0 1 1 1 0 IPP transferase RhoGEF PF00621.15 KFP08388.1 - 1.7e-31 109.4 0.0 2.5e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain DFF40 PF09230.5 KFP08388.1 - 0.051 12.9 0.1 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Clp1 PF06807.9 KFP08389.1 - 8.6e-46 156.1 0.0 1.2e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ANF_receptor PF01094.23 KFP08390.1 - 1e-45 156.0 0.0 1.3e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 KFP08390.1 - 3.8e-20 72.2 8.4 6.3e-20 71.5 5.8 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NCD3G PF07562.9 KFP08390.1 - 4.3e-15 55.1 14.9 4.3e-15 55.1 10.3 2.1 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Peripla_BP_6 PF13458.1 KFP08390.1 - 5.6e-08 32.5 0.0 1e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein Fcf1 PF04900.7 KFP08390.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Fcf1 Peripla_BP_5 PF13433.1 KFP08390.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain tRNA-synt_His PF13393.1 KFP08390.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Sp38 PF07354.7 KFP08390.1 - 1.5 7.4 10.2 2.6 6.6 7.1 1.3 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) PHD PF00628.24 KFP08391.1 - 1.5e-08 34.2 8.2 2.4e-08 33.5 5.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFP08391.1 - 9.1e-06 24.8 4.8 1.5e-05 24.2 3.3 1.4 1 0 0 1 1 1 1 PHD-finger DDA1 PF10172.4 KFP08391.1 - 0.017 14.9 0.1 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase C1_1 PF00130.17 KFP08391.1 - 0.017 14.8 2.1 0.017 14.8 1.5 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AfaD PF05775.7 KFP08391.1 - 0.066 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Enterobacteria AfaD invasin protein zf-CW PF07496.10 KFP08391.1 - 0.17 11.5 3.4 0.39 10.4 2.4 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger DUF3268 PF11672.3 KFP08391.1 - 0.49 10.4 3.2 3.8 7.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Prok-RING_1 PF14446.1 KFP08391.1 - 1.1 9.0 6.5 0.14 11.8 1.1 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 KFP08391.1 - 1.3 9.1 5.0 19 5.4 0.1 2.3 2 0 0 2 2 2 0 C1 domain DUF3395 PF11875.3 KFP08392.1 - 1.1e-43 148.4 0.3 2.3e-43 147.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KFP08392.1 - 2e-19 69.0 2.0 4e-19 68.1 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain Selenoprotein_S PF06936.6 KFP08392.1 - 0.03 13.8 0.1 0.074 12.5 0.1 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) Endonuclease_5 PF04493.9 KFP08392.1 - 0.11 11.7 0.4 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 Endonuclease V CG-1 PF03859.11 KFP08393.1 - 7.5e-44 148.0 1.3 7.5e-44 148.0 0.9 2.1 2 0 0 2 2 2 1 CG-1 domain TIG PF01833.19 KFP08393.1 - 3.7e-09 36.4 0.3 3.7e-09 36.4 0.2 2.6 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 KFP08393.1 - 6.2e-09 36.0 0.2 8.6e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFP08393.1 - 1.9e-06 27.9 0.5 0.12 12.7 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFP08393.1 - 4.8e-06 26.1 1.7 0.11 12.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFP08393.1 - 8e-05 22.5 0.2 0.69 10.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat IQ PF00612.22 KFP08393.1 - 0.00089 18.6 18.9 0.19 11.4 0.3 5.4 5 0 0 5 5 5 3 IQ calmodulin-binding motif Ank_4 PF13637.1 KFP08393.1 - 0.0027 18.1 0.7 0.15 12.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Synaptobrevin PF00957.16 KFP08394.1 - 1.1e-29 101.8 0.5 1.3e-29 101.6 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin ERM PF00769.14 KFP08394.1 - 0.043 13.3 0.2 0.053 13.0 0.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Urotensin_II PF02083.10 KFP08395.1 - 1.3e-06 27.3 1.1 2.1e-06 26.6 0.8 1.4 1 0 0 1 1 1 1 Urotensin II DJ-1_PfpI PF01965.19 KFP08396.1 - 7.5e-34 116.3 0.0 9.4e-34 115.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFP08396.1 - 1.1e-14 53.9 0.0 1.4e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 KFP08396.1 - 0.0061 16.1 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Inhibitor_Mig-6 PF11555.3 KFP08397.1 - 1.4e-24 86.2 10.4 1.4e-24 86.2 7.2 4.3 4 1 1 5 5 5 2 EGFR receptor inhibitor Mig-6 GTPase_binding PF09027.5 KFP08397.1 - 1e-22 79.4 0.0 2.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 GTPase binding MFS_1 PF07690.11 KFP08398.1 - 1.9e-08 33.4 5.1 2.3e-08 33.1 3.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane_3 PF12698.2 KFP08398.1 - 8.1 5.3 11.5 17 4.3 8.0 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Spermine_synth PF01564.12 KFP08399.1 - 4.3e-64 215.8 0.0 6.2e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KFP08399.1 - 7.3e-06 25.6 0.0 8.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP08399.1 - 0.0045 17.5 0.0 0.0081 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 KFP08399.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Somatostatin PF03002.10 KFP08400.1 - 5.1e-12 45.0 7.6 7.2e-12 44.6 5.3 1.2 1 0 0 1 1 1 1 Somatostatin/Cortistatin family CUB PF00431.15 KFP08401.1 - 1.9e-19 69.7 0.0 2.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 CUB domain EGF_CA PF07645.10 KFP08401.1 - 5.4e-08 32.6 7.2 1.1e-07 31.7 5.0 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain FXa_inhibition PF14670.1 KFP08401.1 - 3.3e-07 30.3 9.0 3.3e-07 30.3 6.2 1.7 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 KFP08401.1 - 0.0023 17.5 3.9 0.0023 17.5 2.7 2.3 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF PF00008.22 KFP08401.1 - 0.0031 17.4 8.3 0.007 16.3 5.7 1.6 1 0 0 1 1 1 1 EGF-like domain CUB_2 PF02408.15 KFP08401.1 - 0.037 13.5 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 CUB-like domain RRM_1 PF00076.17 KFP08402.1 - 3.6e-29 100.2 0.2 1.1e-16 60.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP08402.1 - 6.3e-22 77.3 0.1 2.2e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP08402.1 - 9.6e-08 31.7 0.8 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP08402.1 - 0.00071 19.3 0.0 0.076 12.8 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFP08402.1 - 0.14 11.9 0.0 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-C2H2 PF00096.21 KFP08405.1 - 0.0012 19.0 20.4 0.19 12.1 1.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08405.1 - 0.0031 17.7 20.3 0.058 13.7 0.7 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger Nop14 PF04147.7 KFP08406.1 - 0.063 11.1 22.3 0.085 10.7 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF240 PF03086.9 KFP08406.1 - 0.11 12.1 0.2 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 PPP4R2 PF09184.6 KFP08406.1 - 0.68 9.4 20.7 1.1 8.7 14.3 1.3 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.3 KFP08406.1 - 3.8 7.4 25.1 6.9 6.5 17.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid PF03115.9 KFP08406.1 - 4 5.5 7.8 5.3 5.1 5.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TFIIA PF03153.8 KFP08406.1 - 6.6 6.5 28.2 0.048 13.5 13.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.8 KFP08407.1 - 2.8e-24 85.7 0.8 2.8e-24 85.7 0.5 3.8 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF948 PF06103.6 KFP08407.1 - 0.022 14.6 1.3 0.054 13.3 0.9 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Beach PF02138.13 KFP08407.1 - 0.03 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Beige/BEACH domain Cob_adeno_trans PF01923.13 KFP08407.1 - 0.066 13.0 0.4 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Ribosomal_60s PF00428.14 KFP08407.1 - 0.2 12.0 3.9 0.65 10.4 2.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein AATF-Che1 PF13339.1 KFP08407.1 - 0.25 11.4 10.0 0.87 9.7 0.9 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor CAF-1_p150 PF11600.3 KFP08407.1 - 0.27 10.6 11.7 0.55 9.5 8.1 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cor1 PF04803.7 KFP08407.1 - 2 8.1 10.2 4.1 7.1 2.4 2.5 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region PBP1_TM PF14812.1 KFP08407.1 - 5 7.5 9.2 11 6.4 6.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DFF-C PF09033.5 KFP08408.1 - 1.9e-52 177.4 16.5 1.3e-51 174.7 6.5 2.1 2 0 0 2 2 2 2 DNA Fragmentation factor 45kDa, C terminal domain CIDE-N PF02017.10 KFP08408.1 - 1.4e-22 79.2 0.2 1.6e-21 75.8 0.0 2.6 2 0 0 2 2 2 1 CIDE-N domain COG2 PF06148.6 KFP08408.1 - 0.013 15.4 2.7 0.013 15.4 1.9 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PSK_trans_fac PF07704.6 KFP08408.1 - 0.028 15.1 6.6 1.2 9.8 2.2 2.7 2 1 0 2 2 2 0 Rv0623-like transcription factor Mnd1 PF03962.10 KFP08408.1 - 4.2 6.9 14.3 0.32 10.6 4.8 2.4 2 1 0 2 2 2 0 Mnd1 family Gon7 PF08738.5 KFP08408.1 - 4.6 7.2 7.0 14 5.7 0.2 2.6 2 1 0 2 2 2 0 Gon7 family CENP-S PF15630.1 KFP08409.1 - 8.4e-33 112.3 0.7 1.2e-32 111.8 0.5 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KFP08409.1 - 2.9e-05 24.1 1.4 3.9e-05 23.6 0.3 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 KFP08409.1 - 4.7e-05 23.1 0.1 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 KFP08409.1 - 0.00034 19.9 0.6 0.00034 19.9 0.4 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KFP08409.1 - 0.00054 19.6 0.4 0.0015 18.2 0.1 1.7 1 1 0 2 2 2 1 Bromodomain associated CFTR_R PF14396.1 KFP08409.1 - 0.027 13.8 1.6 0.034 13.4 1.1 1.3 1 1 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain DUF3540 PF12059.3 KFP08409.1 - 0.041 13.5 0.9 0.043 13.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) Siah-Interact_N PF09032.6 KFP08409.1 - 0.12 12.4 2.9 0.21 11.6 2.0 1.4 1 0 0 1 1 1 0 Siah interacting protein, N terminal TAF PF02969.12 KFP08409.1 - 0.12 12.3 1.2 0.32 10.9 0.4 2.1 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) 6PGD PF00393.14 KFP08410.1 - 2.6e-139 463.4 0.0 3.2e-139 463.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFP08410.1 - 5.5e-51 172.6 0.0 7.7e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFP08410.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Kinesin PF00225.18 KFP08411.1 - 1.2e-116 389.1 0.5 1.9e-116 388.4 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KFP08411.1 - 2.7e-39 134.0 0.0 5.5e-39 133.0 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KFP08411.1 - 1.3e-14 54.2 0.1 1.4e-13 50.8 0.0 2.8 3 0 0 3 3 3 1 PH domain FHA PF00498.21 KFP08411.1 - 7.1e-08 32.4 0.2 3.3e-07 30.3 0.1 2.3 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 KFP08411.1 - 2 8.5 6.2 0.24 11.4 0.2 2.4 2 0 0 2 2 2 0 Kinesin protein 1B Ufd2P_core PF10408.4 KFP08412.1 - 8.9e-184 612.2 12.9 1.4e-183 611.5 9.0 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KFP08412.1 - 9.5e-24 83.1 0.8 2.5e-23 81.8 0.2 2.1 2 0 0 2 2 2 1 U-box domain Lipocalin PF00061.18 KFP08413.1 - 5.5e-19 68.5 0.8 5.9e-19 68.4 0.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.1 KFP08413.1 - 1.8e-05 24.4 0.3 2.1e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family CTP_transf_2 PF01467.21 KFP08414.1 - 1.1e-36 126.2 0.1 1.7e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase SWIB PF02201.13 KFP08414.1 - 0.071 12.8 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 SWIB/MDM2 domain ICAT PF06384.6 KFP08415.1 - 7.4e-36 121.7 3.0 1.4e-35 120.8 0.2 2.3 2 1 0 2 2 2 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.6 KFP08415.1 - 0.00018 21.0 0.4 0.00025 20.6 0.3 1.3 1 0 0 1 1 1 1 CAMP factor (Cfa) DUF3313 PF11769.3 KFP08415.1 - 0.0013 18.1 0.1 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) DUF892 PF05974.7 KFP08415.1 - 0.0037 17.0 2.3 0.0068 16.2 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF892) ISG65-75 PF11727.3 KFP08415.1 - 0.012 14.6 1.3 0.018 14.1 0.9 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein GvpG PF05120.7 KFP08415.1 - 0.025 14.3 0.2 0.025 14.3 0.2 2.4 2 0 0 2 2 2 0 Gas vesicle protein G V_ATPase_I PF01496.14 KFP08415.1 - 0.043 11.6 2.2 0.048 11.5 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.1 KFP08415.1 - 0.075 12.9 10.3 0.075 12.9 5.2 2.2 1 1 1 2 2 2 0 FlxA-like protein NIT PF08376.5 KFP08415.1 - 0.08 12.4 3.5 0.076 12.5 0.4 2.1 1 1 1 2 2 2 0 Nitrate and nitrite sensing DUF2229 PF09989.4 KFP08415.1 - 0.083 12.3 1.0 0.16 11.4 0.6 1.6 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) MCR_C PF04609.7 KFP08415.1 - 0.084 11.6 1.8 4.6 5.9 0.0 2.1 1 1 1 2 2 2 0 Methyl-coenzyme M reductase operon protein C CK2S PF15011.1 KFP08415.1 - 0.094 12.4 8.3 0.82 9.4 0.0 2.9 1 1 1 3 3 3 0 Casein Kinase 2 substrate WXG100 PF06013.7 KFP08415.1 - 0.098 12.6 0.5 0.098 12.6 0.4 2.4 3 0 0 3 3 2 0 Proteins of 100 residues with WXG EAP30 PF04157.11 KFP08415.1 - 0.15 11.2 5.3 0.27 10.3 3.5 1.6 1 1 0 1 1 1 0 EAP30/Vps36 family DUF4254 PF14063.1 KFP08415.1 - 0.18 11.3 3.4 0.31 10.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) GrpE PF01025.14 KFP08415.1 - 0.21 11.1 3.7 0.33 10.4 2.6 1.4 1 0 0 1 1 1 0 GrpE DUF1098 PF06497.6 KFP08415.1 - 0.24 11.4 2.5 0.25 11.4 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) Prominin PF05478.6 KFP08415.1 - 0.26 8.7 3.0 0.33 8.4 1.9 1.3 1 1 0 1 1 1 0 Prominin Laminin_II PF06009.7 KFP08415.1 - 0.26 11.0 6.2 2.2 8.0 0.9 2.9 2 1 1 3 3 3 0 Laminin Domain II Cauli_AT PF03233.8 KFP08415.1 - 0.27 10.9 3.1 0.58 9.8 2.2 1.5 1 0 0 1 1 1 0 Aphid transmission protein NPV_P10 PF05531.7 KFP08415.1 - 0.36 11.0 4.1 1.2 9.4 2.4 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_p24 PF05073.7 KFP08415.1 - 0.85 9.1 4.8 12 5.4 1.9 2.1 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Allexi_40kDa PF05549.6 KFP08415.1 - 0.86 8.8 4.0 0.89 8.8 2.1 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF883 PF05957.8 KFP08415.1 - 1.3 9.4 4.8 2.7 8.4 0.8 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) MRP-S23 PF10484.4 KFP08415.1 - 1.5 8.6 3.7 8.8 6.2 1.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 IncA PF04156.9 KFP08415.1 - 1.6 8.2 15.6 1.5 8.3 9.8 1.6 1 1 1 2 2 2 0 IncA protein DUF148 PF02520.12 KFP08415.1 - 1.8 8.3 6.6 2.6 7.8 3.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF948 PF06103.6 KFP08415.1 - 2.5 8.0 4.9 21 5.0 2.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.13 KFP08415.1 - 3.4 6.6 6.7 4.2 6.3 4.0 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.6 KFP08415.1 - 5.1 7.5 7.8 6.5 7.2 3.3 2.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal MerR-DNA-bind PF09278.6 KFP08415.1 - 9.4 6.7 10.3 0.45 10.9 1.9 2.6 3 0 0 3 3 2 0 MerR, DNA binding ICAT PF06384.6 KFP08416.1 - 5.7e-28 96.5 0.1 6.2e-28 96.4 0.1 1.0 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT DUF3140 PF11338.3 KFP08416.1 - 0.044 13.9 0.0 0.047 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Cadherin PF00028.12 KFP08417.1 - 9.4e-15 54.6 0.0 7e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 Cadherin domain Laminin_G_3 PF13385.1 KFP08417.1 - 6.1e-09 36.3 0.0 1.1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CDC45 PF02724.9 KFP08417.1 - 0.0006 17.9 3.2 0.0008 17.5 2.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Glyco_hydro_16 PF00722.16 KFP08417.1 - 0.0045 16.3 0.5 0.013 14.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1510 PF07423.6 KFP08417.1 - 0.017 14.4 11.6 0.029 13.7 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Laminin_G_2 PF02210.19 KFP08417.1 - 0.023 14.7 0.0 0.094 12.7 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain SID-1_RNA_chan PF13965.1 KFP08417.1 - 0.025 12.7 0.7 0.036 12.2 0.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.1 KFP08417.1 - 0.086 13.2 0.1 0.67 10.3 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ycf1 PF05758.7 KFP08417.1 - 0.13 9.9 0.6 0.17 9.5 0.4 1.1 1 0 0 1 1 1 0 Ycf1 PI3_PI4_kinase PF00454.22 KFP08418.1 - 3e-56 190.5 0.1 7.5e-56 189.2 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFP08418.1 - 3.8e-55 185.9 3.4 7.4e-55 184.9 2.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_p85B PF02192.11 KFP08418.1 - 1.9e-34 116.9 0.0 5.1e-34 115.5 0.0 1.8 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain PI3K_C2 PF00792.19 KFP08418.1 - 1e-33 116.1 0.6 2.5e-33 114.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 KFP08418.1 - 1.9e-24 85.6 0.0 9.2e-24 83.4 0.0 2.2 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain TpcC PF12642.2 KFP08418.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Yae1_N PF09811.4 KFP08419.1 - 1.2e-06 27.8 55.2 1.5e+04 -32.7 38.3 6.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Galactosyl_T PF01762.16 KFP08420.1 - 1.2e-29 103.3 0.0 1.6e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase EF-hand_7 PF13499.1 KFP08421.1 - 1.9e-19 69.5 10.6 4.3e-06 26.7 0.1 3.8 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KFP08421.1 - 4.3e-19 66.3 4.6 0.00076 18.6 0.0 6.3 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.1 KFP08421.1 - 6.6e-12 44.2 1.5 0.11 12.4 0.0 6.0 6 0 0 6 6 6 3 EF-hand domain EF-hand_5 PF13202.1 KFP08421.1 - 1.1e-10 40.3 2.0 0.0017 17.6 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KFP08421.1 - 2.5e-07 30.1 5.9 0.012 15.2 0.0 5.1 5 1 1 6 6 6 4 EF-hand domain pair RasGEF_N_2 PF14663.1 KFP08421.1 - 0.011 15.6 0.3 0.18 11.7 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pex14_N PF04695.8 KFP08421.1 - 0.026 14.5 0.1 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SPARC_Ca_bdg PF10591.4 KFP08421.1 - 0.072 13.1 11.1 1.7 8.7 0.7 3.6 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF826 PF05696.6 KFP08421.1 - 0.087 12.9 0.7 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF826) TNFR_c6 PF00020.13 KFP08422.1 - 2.4e-14 53.0 35.4 2.7e-07 30.5 6.7 3.6 3 1 1 4 4 4 4 TNFR/NGFR cysteine-rich region GCC2_GCC3 PF07699.8 KFP08422.1 - 0.26 10.9 26.8 0.073 12.6 1.9 3.3 2 2 1 3 3 3 0 GCC2 and GCC3 TTL PF03133.10 KFP08423.1 - 6.9e-31 107.2 0.2 1.1e-30 106.6 0.2 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family DUF4501 PF14946.1 KFP08424.1 - 8.1e-30 103.6 0.5 8.4e-30 103.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) zf-RING_5 PF14634.1 KFP08425.1 - 1.2e-09 37.6 7.2 4e-09 36.0 5.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFP08425.1 - 3.2e-07 30.0 7.6 3.2e-07 30.0 5.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 KFP08425.1 - 1.3e-06 27.9 3.1 1.9e-06 27.5 1.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFP08425.1 - 1.4e-06 27.9 4.8 1.4e-06 27.9 3.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP08425.1 - 5.3e-06 26.0 7.7 5.3e-06 26.0 5.3 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP08425.1 - 5.5e-06 26.3 7.8 5.5e-06 26.3 5.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP08425.1 - 2.3e-05 24.1 7.1 0.00012 21.9 4.9 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFP08425.1 - 0.013 15.0 5.4 0.038 13.5 3.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 KFP08425.1 - 0.077 12.8 0.3 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-MIZ PF02891.15 KFP08425.1 - 2.9 7.4 7.7 18 4.9 5.3 2.4 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 KFP08425.1 - 4.8 7.3 10.3 0.43 10.7 3.2 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger zf-CCCH_2 PF14608.1 KFP08426.1 - 0.83 9.7 6.7 64 3.7 0.0 5.1 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type PH PF00169.24 KFP08427.1 - 5.2e-09 36.2 0.3 8.4e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 PH domain DUF1908 PF08926.6 KFP08427.1 - 0.041 12.6 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Kelch_1 PF01344.20 KFP08428.1 - 4.6e-76 250.1 11.2 4e-17 61.4 0.1 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KFP08428.1 - 1.8e-46 154.4 5.9 6.3e-10 38.8 0.0 6.4 1 1 5 6 6 6 6 Kelch motif BACK PF07707.10 KFP08428.1 - 6.4e-38 128.7 0.1 1.4e-37 127.6 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.1 KFP08428.1 - 1.1e-34 117.9 3.2 1.4e-08 34.3 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain BTB PF00651.26 KFP08428.1 - 9e-34 115.8 0.7 1.4e-33 115.1 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 KFP08428.1 - 2.9e-30 103.7 12.3 4.1e-08 33.1 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP08428.1 - 1.4e-25 88.0 2.5 0.00011 21.7 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KFP08428.1 - 1.4e-10 40.8 5.5 0.19 11.7 0.0 5.6 5 0 0 5 5 5 4 Kelch motif PQQ_3 PF13570.1 KFP08428.1 - 1.1 9.6 10.9 20 5.6 0.0 5.6 6 0 0 6 6 6 0 PQQ-like domain Noc2 PF03715.8 KFP08429.1 - 6.5e-107 356.8 6.8 1.2e-106 355.9 4.7 1.4 1 0 0 1 1 1 1 Noc2p family Carb_anhydrase PF00194.16 KFP08430.1 - 7.3e-81 270.9 0.1 9.8e-81 270.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Pentaxin PF00354.12 KFP08430.1 - 2e-41 141.6 0.0 3e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.1 KFP08430.1 - 9.7e-12 45.3 1.6 9.7e-12 45.3 1.1 1.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily AhpC-TSA_2 PF13911.1 KFP08430.1 - 0.053 13.4 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Sugar_tr PF00083.19 KFP08431.1 - 8e-128 426.8 27.1 9.1e-128 426.6 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP08431.1 - 1e-19 70.5 54.3 1.2e-18 66.9 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_1 PF04531.8 KFP08431.1 - 0.66 10.0 11.6 3.6 7.7 0.1 3.9 3 1 2 5 5 5 0 Bacteriophage holin 7tm_2 PF00002.19 KFP08432.1 - 8.8e-11 41.3 13.0 8.8e-11 41.3 9.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KFP08432.1 - 1.8e-09 36.9 9.3 1.8e-09 36.9 6.4 2.0 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor Frizzled PF01534.12 KFP08432.1 - 0.018 13.8 9.3 0.18 10.5 6.4 2.1 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region Glucosamine_iso PF01182.15 KFP08433.1 - 3.1e-55 186.9 0.0 6.2e-55 186.0 0.0 1.5 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_C PF02781.11 KFP08433.1 - 2.3e-46 157.9 0.0 3.5e-40 137.7 0.0 2.1 2 0 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFP08433.1 - 1.6e-36 126.2 0.0 7.5e-36 124.0 0.0 2.1 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain SPRY PF00622.23 KFP08434.1 - 7.6e-18 64.7 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 SPRY domain SOCS_box PF07525.11 KFP08434.1 - 8.5e-15 54.3 2.6 1.7e-14 53.3 1.8 1.6 1 0 0 1 1 1 1 SOCS box RVT_1 PF00078.22 KFP08435.1 - 0.019 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2448 PF10476.4 KFP08436.1 - 5.3e-77 257.9 1.2 8e-77 257.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) Ima1_N PF09779.4 KFP08436.1 - 2.1e-36 125.3 12.6 2.5e-36 125.0 7.9 1.8 2 0 0 2 2 2 1 Ima1 N-terminal domain Herpes_pp85 PF04637.7 KFP08436.1 - 0.083 11.1 1.3 2.1 6.5 0.6 2.4 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Zn_Tnp_IS1 PF03811.8 KFP08436.1 - 0.71 9.4 11.8 1.4 8.5 0.5 3.9 3 0 0 3 3 3 0 InsA N-terminal domain Mito_carr PF00153.22 KFP08437.1 - 2.7e-64 212.8 2.3 2e-21 75.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Phospholip_A2_1 PF00068.14 KFP08438.1 - 1.1e-21 77.1 1.9 1.2e-21 77.0 1.3 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFP08438.1 - 0.041 13.6 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.7 KFP08438.1 - 3.7 7.5 7.6 5.8 6.9 5.1 1.5 1 1 1 2 2 2 0 Phospholipase A2 Phospholip_A2_1 PF00068.14 KFP08439.1 - 8.9e-29 100.0 12.6 9.5e-29 99.9 8.7 1.0 1 0 0 1 1 1 1 Phospholipase A2 Parvo_coat_N PF08398.5 KFP08439.1 - 0.0089 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus coat protein VP1 Phospholip_A2_2 PF05826.7 KFP08439.1 - 0.014 15.2 14.3 0.99 9.3 9.9 2.5 1 1 0 1 1 1 0 Phospholipase A2 PLA2G12 PF06951.6 KFP08439.1 - 3 7.4 11.7 0.43 10.1 2.9 2.1 2 0 0 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) OTU PF02338.14 KFP08440.1 - 1.6e-15 57.7 0.3 2e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 OTU-like cysteine protease UBA_4 PF14555.1 KFP08440.1 - 0.0054 16.2 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Peptidase_C65 PF10275.4 KFP08440.1 - 0.0091 15.3 4.4 0.064 12.5 0.0 2.6 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF726 PF05277.7 KFP08441.1 - 8.2e-121 403.0 2.6 9.9e-121 402.8 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.7 KFP08441.1 - 5.2e-05 22.6 0.0 8.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 KFP08441.1 - 0.0065 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase VirJ PF06057.6 KFP08441.1 - 0.01 15.6 0.0 0.05 13.3 0.0 2.1 3 0 0 3 3 3 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 KFP08441.1 - 0.071 12.7 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_5 PF12695.2 KFP08441.1 - 0.083 12.6 0.2 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFP08441.1 - 0.085 12.7 0.1 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family 5TM-5TMR_LYT PF07694.7 KFP08441.1 - 5.2 6.3 10.8 11 5.3 7.4 1.7 1 1 0 1 1 1 0 5TMR of 5TMR-LYT 7tm_1 PF00001.16 KFP08442.1 - 3.1e-67 226.4 19.6 4.1e-67 226.0 13.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.4 KFP08442.1 - 0.0013 17.8 13.0 0.0013 17.8 9.0 1.5 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.4 KFP08442.1 - 0.0042 16.2 20.5 0.0063 15.7 11.2 2.5 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx DAN PF03045.10 KFP08443.1 - 2.2e-33 114.2 4.3 3.3e-33 113.7 3.0 1.2 1 0 0 1 1 1 1 DAN domain Cys_knot PF00007.17 KFP08443.1 - 8.2e-07 29.0 6.3 1.2e-06 28.5 4.3 1.2 1 0 0 1 1 1 1 Cystine-knot domain DUF543 PF04418.7 KFP08444.1 - 5.3e-28 96.7 0.9 5.7e-28 96.6 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) F_actin_cap_B PF01115.12 KFP08445.1 - 1.3e-111 371.5 0.0 1.6e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit CENP-C_mid PF15620.1 KFP08445.1 - 0.035 13.8 0.7 0.046 13.4 0.5 1.2 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region PQ-loop PF04193.9 KFP08446.1 - 1.1e-18 66.4 7.2 1.5e-11 43.6 1.5 2.5 2 0 0 2 2 2 2 PQ loop repeat Aldo_ket_red PF00248.16 KFP08447.1 - 1.1e-42 145.8 0.0 1.2e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L10 PF00466.15 KFP08448.1 - 6.1e-14 51.7 0.1 8.4e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 TraF PF13728.1 KFP08448.1 - 0.0059 16.1 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein 7TMR-HDED PF07697.6 KFP08448.1 - 0.045 13.4 0.0 5 6.7 0.0 2.2 1 1 1 2 2 2 0 7TM-HD extracellular DUF1620 PF07774.8 KFP08449.1 - 1.4e-62 210.8 0.1 4.1e-62 209.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KFP08449.1 - 9.7e-14 51.4 1.0 1.2e-08 34.6 0.2 3.7 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 KFP08449.1 - 4.8e-05 22.6 0.1 0.17 11.4 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat Filament PF00038.16 KFP08450.1 - 1.9e-20 73.5 16.6 1.2e-11 44.6 0.3 2.1 2 0 0 2 2 2 2 Intermediate filament protein Snapin_Pallidin PF14712.1 KFP08450.1 - 0.00019 21.6 0.8 0.00063 20.0 0.5 1.9 1 0 0 1 1 1 1 Snapin/Pallidin TMF_DNA_bd PF12329.3 KFP08450.1 - 0.018 14.8 1.9 0.018 14.8 1.3 2.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 KFP08450.1 - 0.066 12.8 5.2 1.8 8.2 0.2 2.7 2 0 0 2 2 2 0 Prefoldin subunit TLE_N PF03920.10 KFP08450.1 - 2.5 7.9 6.6 0.73 9.6 0.3 2.8 3 1 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain CENP-Q PF13094.1 KFP08450.1 - 3.1 7.7 13.6 3.6 7.6 1.8 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Aldedh PF00171.17 KFP08451.1 - 7.6e-97 324.5 0.0 9e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PAX PF00292.13 KFP08452.1 - 5.1e-75 249.1 0.8 7.9e-75 248.5 0.6 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeobox PF00046.24 KFP08452.1 - 2.1e-23 81.6 6.9 2.1e-23 81.6 4.8 1.6 2 0 0 2 2 2 1 Homeobox domain Pax7 PF12360.3 KFP08452.1 - 4e-21 75.0 8.5 1e-20 73.6 5.9 1.8 1 0 0 1 1 1 1 Paired box protein 7 HTH_23 PF13384.1 KFP08452.1 - 4.1e-06 26.2 1.0 0.00058 19.4 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 KFP08452.1 - 1.7e-05 25.5 4.7 0.0086 16.8 0.1 2.9 2 1 0 2 2 2 2 Homeodomain-like domain Homeobox_KN PF05920.6 KFP08452.1 - 4.5e-05 23.0 0.4 0.00014 21.4 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain Kelch_1 PF01344.20 KFP08453.1 - 4.7e-20 70.8 0.1 5.2e-09 35.4 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 KFP08453.1 - 8.3e-18 63.7 0.5 0.0001 22.3 0.1 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.1 KFP08453.1 - 9.9e-06 25.5 0.7 0.15 12.2 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP08453.1 - 3.1e-05 23.6 0.1 0.16 11.7 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 KFP08453.1 - 5e-05 22.8 0.8 0.4 10.5 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 KFP08453.1 - 0.047 13.6 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Ig_2 PF13895.1 KFP08454.1 - 5.3e-15 55.3 0.0 0.0002 21.4 0.0 3.9 4 0 0 4 4 4 3 Immunoglobulin domain Ig_3 PF13927.1 KFP08454.1 - 4.3e-12 46.3 0.1 0.0028 18.1 0.0 4.6 4 1 0 4 4 4 3 Immunoglobulin domain I-set PF07679.11 KFP08454.1 - 2.3e-10 40.1 0.0 0.00017 21.3 0.0 3.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain V-set PF07686.12 KFP08454.1 - 2.3e-08 33.9 0.0 1.8e-07 31.0 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin V-set domain C2-set_2 PF08205.7 KFP08454.1 - 1.8e-06 27.7 0.0 0.024 14.5 0.0 3.4 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain C1-set PF07654.10 KFP08454.1 - 0.00023 21.0 0.0 0.14 12.2 0.0 3.6 3 0 0 3 3 3 1 Immunoglobulin C1-set domain ig PF00047.20 KFP08454.1 - 0.00029 20.9 0.0 0.34 11.0 0.1 3.5 3 1 0 3 3 3 2 Immunoglobulin domain RhoGEF PF00621.15 KFP08455.1 - 1.7e-42 145.3 0.7 3.7e-42 144.2 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF1690 PF07956.6 KFP08455.1 - 0.037 13.9 1.5 0.094 12.6 1.0 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Cytochrom_D1 PF02239.11 KFP08455.1 - 0.057 11.6 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain GATase_4 PF13230.1 KFP08455.1 - 0.097 11.3 0.1 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II RCC1 PF00415.13 KFP08456.1 - 8.9e-60 198.7 8.0 2.5e-16 59.5 0.0 7.2 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFP08456.1 - 3.9e-34 115.5 11.4 7.8e-09 34.9 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat PAD PF03068.10 KFP08457.1 - 3.1e-218 723.7 0.0 3.8e-218 723.4 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.5 KFP08457.1 - 1.3e-65 219.7 0.0 2e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.5 KFP08457.1 - 2.8e-39 133.6 0.0 5.1e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.10 KFP08458.1 - 2.2e-211 701.2 0.0 2.9e-211 700.8 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.5 KFP08458.1 - 1.2e-60 203.5 0.0 1.8e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.5 KFP08458.1 - 3.2e-17 62.6 0.4 1e-16 60.9 0.3 1.9 2 0 0 2 2 2 1 Protein-arginine deiminase (PAD) N-terminal domain PAD PF03068.10 KFP08459.1 - 4e-193 641.1 0.0 4.8e-193 640.8 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.5 KFP08459.1 - 8e-60 200.8 0.0 1.3e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain PAD_N PF08526.5 KFP08459.1 - 2.9e-27 94.9 0.0 5.3e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain Fer2_3 PF13085.1 KFP08460.1 - 5.7e-32 109.8 0.0 1.2e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KFP08460.1 - 2.2e-10 40.7 4.8 2.2e-10 40.7 3.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KFP08460.1 - 3.4e-09 36.5 4.0 3.4e-09 36.5 2.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KFP08460.1 - 1.2e-08 35.2 6.1 3.3e-07 30.6 0.6 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFP08460.1 - 0.001 19.3 10.5 0.026 14.7 0.6 3.4 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFP08460.1 - 0.0031 17.2 6.5 0.0031 17.2 4.5 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KFP08460.1 - 0.0075 15.9 3.3 0.011 15.4 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KFP08460.1 - 0.013 15.8 6.0 0.013 15.8 4.1 3.0 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 KFP08460.1 - 1.2 9.7 6.6 1.6 9.3 0.1 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_4 PF12800.2 KFP08460.1 - 7.4 7.1 16.3 1.3 9.5 1.4 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain E1-E2_ATPase PF00122.15 KFP08461.1 - 7.6e-36 123.2 0.0 1e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KFP08461.1 - 0.00011 21.6 0.1 0.00027 20.3 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFP08461.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFP08461.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MARVEL PF01284.18 KFP08461.1 - 0.018 14.8 0.4 0.018 14.8 0.3 2.3 2 1 0 2 2 2 0 Membrane-associating domain Rootletin PF15035.1 KFP08462.1 - 4.8e-15 55.9 14.2 4.8e-15 55.9 9.8 2.6 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.5 KFP08462.1 - 5.9e-05 23.2 10.7 5.9e-05 23.2 7.4 1.6 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family LemA PF04011.7 KFP08462.1 - 0.56 9.2 11.8 2.6 7.1 0.2 2.1 1 1 0 2 2 2 0 LemA family Med28 PF11594.3 KFP08462.1 - 0.59 10.3 12.4 0.38 10.9 3.5 2.4 1 1 0 2 2 2 0 Mediator complex subunit 28 ERp29 PF07749.7 KFP08462.1 - 3.6 8.2 12.6 0.36 11.5 0.4 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF2951 PF11166.3 KFP08462.1 - 9.2 6.1 12.6 0.19 11.6 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) HAUS6_N PF14661.1 KFP08462.1 - 9.6 5.4 19.5 1.6 8.0 9.9 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF1681 PF07933.9 KFP08463.1 - 1.7e-48 164.1 0.1 2e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SUZ PF12752.2 KFP08464.1 - 1.3e-13 51.2 0.1 1.3e-13 51.2 0.0 2.0 3 0 0 3 3 3 1 SUZ domain SUZ-C PF12901.2 KFP08464.1 - 7.6e-11 41.3 7.5 7.6e-11 41.3 5.2 2.1 2 0 0 2 2 2 1 SUZ-C motif Kelch_3 PF13415.1 KFP08465.1 - 2.1e-30 104.1 11.3 2.6e-09 37.0 0.0 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP08465.1 - 2e-29 101.0 5.3 3.2e-09 36.4 0.1 5.5 3 1 2 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KFP08465.1 - 4.2e-22 77.6 2.2 1.3e-07 31.4 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KFP08465.1 - 1.5e-20 72.0 7.4 1.6e-08 33.9 0.2 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFP08465.1 - 2.4e-19 68.5 6.2 2.6e-05 24.1 0.0 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 KFP08465.1 - 2.2e-18 65.4 0.4 2.1e-06 27.1 0.0 5.6 5 0 0 5 5 5 3 Kelch motif F-box-like PF12937.2 KFP08465.1 - 2.9e-09 36.5 1.1 4.1e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFP08465.1 - 2.3e-07 30.3 0.0 4.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Pkinase_Tyr PF07714.12 KFP08466.1 - 5.2e-97 323.9 0.0 6.2e-97 323.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFP08466.1 - 2.1e-48 164.7 0.0 2.7e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.1 KFP08466.1 - 4.7e-15 55.7 0.4 7.7e-15 55.0 0.3 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RIO1 PF01163.17 KFP08466.1 - 0.14 11.5 0.6 2.4 7.4 0.0 2.6 2 1 1 3 3 3 0 RIO1 family HSP20 PF00011.16 KFP08467.1 - 2.4e-16 59.4 0.7 3.6e-16 58.8 0.0 1.6 2 0 0 2 2 2 1 Hsp20/alpha crystallin family CS PF04969.11 KFP08467.1 - 0.05 14.1 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 CS domain zf-H2C2_2 PF13465.1 KFP08468.1 - 5.8e-48 158.9 47.6 4.5e-09 36.1 0.1 7.4 8 0 0 8 8 7 7 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08468.1 - 4.8e-36 120.9 49.4 2.4e-06 27.5 0.7 7.1 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08468.1 - 1.4e-24 84.5 42.9 7e-06 26.0 0.6 7.0 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP08468.1 - 9.4e-19 67.0 20.6 0.00038 20.4 0.0 6.5 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP08468.1 - 2.5e-10 40.1 28.5 0.03 14.5 0.1 6.3 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-BED PF02892.10 KFP08468.1 - 1.6e-09 37.3 37.6 0.0052 16.5 0.1 6.4 3 2 3 6 6 6 4 BED zinc finger zf-C2H2_6 PF13912.1 KFP08468.1 - 2.9e-06 26.9 38.8 0.24 11.3 0.2 7.3 7 1 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP08468.1 - 6.1e-06 26.1 6.7 0.018 15.2 0.1 6.8 7 2 0 7 7 6 3 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 KFP08468.1 - 6.1e-06 25.7 21.8 0.29 10.8 0.1 6.7 6 0 0 6 6 6 2 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFP08468.1 - 2.4e-05 24.2 16.9 0.22 11.5 0.1 5.7 6 0 0 6 6 6 2 zinc-finger C1_1 PF00130.17 KFP08468.1 - 7.7e-05 22.3 23.7 0.056 13.1 1.6 4.7 1 1 4 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.7 KFP08468.1 - 0.00013 22.0 29.5 0.031 14.4 5.9 4.9 1 1 5 6 6 6 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KFP08468.1 - 0.00019 21.4 27.8 0.82 9.8 0.2 5.9 1 1 5 6 6 6 3 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.5 KFP08468.1 - 0.0033 17.3 35.8 0.76 9.7 0.1 6.1 4 2 1 5 5 5 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFP08468.1 - 0.0038 16.9 1.9 0.0038 16.9 1.3 4.5 3 2 1 5 5 5 1 Transposase zinc-ribbon domain Elf1 PF05129.8 KFP08468.1 - 0.0068 16.0 1.0 0.0068 16.0 0.7 3.9 1 1 3 4 4 4 1 Transcription elongation factor Elf1 like HypA PF01155.14 KFP08468.1 - 0.0088 15.7 17.9 0.12 12.1 2.1 4.0 1 1 1 2 2 2 1 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 KFP08468.1 - 0.038 13.7 19.3 5.9 6.7 0.2 6.0 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 BolA PF01722.13 KFP08468.1 - 0.051 13.5 4.2 0.54 10.2 0.0 3.3 2 1 0 2 2 2 0 BolA-like protein ROS_MUCR PF05443.6 KFP08468.1 - 0.059 13.1 1.6 2.1 8.1 0.3 2.8 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-CHCC PF10276.4 KFP08468.1 - 0.07 12.9 22.1 0.61 9.9 0.1 5.8 6 0 0 6 6 6 0 Zinc-finger domain FYVE PF01363.16 KFP08468.1 - 0.079 12.8 29.5 1 9.3 7.3 4.1 2 1 1 3 3 3 0 FYVE zinc finger GAGA PF09237.6 KFP08468.1 - 0.1 12.1 18.9 1 8.9 0.0 5.1 1 1 5 6 6 6 0 GAGA factor SprT-like PF10263.4 KFP08468.1 - 0.13 11.8 19.2 1.4e+03 -1.3 13.2 3.1 1 1 0 1 1 1 0 SprT-like family XPA_N PF01286.13 KFP08468.1 - 0.47 10.1 31.6 0.87 9.3 0.1 6.5 7 0 0 7 7 7 0 XPA protein N-terminal zf-trcl PF13451.1 KFP08468.1 - 0.5 10.0 0.1 0.5 10.0 0.1 5.6 6 0 0 6 6 6 0 Probable zinc-binding domain DUF164 PF02591.10 KFP08468.1 - 0.62 9.9 19.8 1.8 8.4 0.2 5.4 6 0 0 6 6 6 0 Putative zinc ribbon domain Desulfoferrod_N PF06397.7 KFP08468.1 - 0.66 9.4 0.1 0.66 9.4 0.1 5.2 6 0 0 6 6 6 0 Desulfoferrodoxin, N-terminal domain Rep_fac-A_C PF08646.5 KFP08468.1 - 0.78 9.4 12.5 2.7 7.6 0.0 3.9 1 1 2 4 4 4 0 Replication factor-A C terminal domain T4_baseplate PF12322.3 KFP08468.1 - 0.83 8.8 5.8 1.9 7.6 0.1 2.9 2 1 1 3 3 3 0 T4 bacteriophage base plate protein PyrI_C PF02748.10 KFP08468.1 - 2.2 7.7 23.6 1 8.8 0.6 5.5 2 1 4 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-HYPF PF07503.7 KFP08468.1 - 2.3 7.6 16.0 6.9 6.1 0.0 5.3 6 0 0 6 6 6 0 HypF finger Trm112p PF03966.11 KFP08468.1 - 3.4 8.1 8.1 5.7 7.3 3.3 2.9 2 1 0 2 2 1 0 Trm112p-like protein zf-FCS PF06467.9 KFP08468.1 - 3.8 7.2 23.1 0.63 9.7 0.3 5.6 4 1 2 6 6 6 0 MYM-type Zinc finger with FCS sequence motif zf-AN1 PF01428.11 KFP08468.1 - 5.4 6.9 29.7 6.2 6.7 0.2 6.1 6 0 0 6 6 6 0 AN1-like Zinc finger FYDLN_acid PF09538.5 KFP08468.1 - 9.2 6.8 14.3 42 4.7 1.1 5.0 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) SPOC PF07744.8 KFP08469.1 - 1.8e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.17 KFP08471.1 - 4.2e-28 96.7 1.2 2.2e-14 52.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP08471.1 - 1.9e-21 75.7 0.2 1e-08 35.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP08471.1 - 5.4e-15 54.9 3.2 4.5e-06 26.4 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFP08471.1 - 0.0052 16.6 0.1 2 8.2 0.0 2.5 3 0 0 3 3 3 2 RNA binding motif Mito_carr PF00153.22 KFP08473.1 - 1.8e-54 181.4 2.1 8.1e-17 60.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PH PF00169.24 KFP08474.1 - 7.1e-14 51.8 0.1 2.1e-12 47.1 0.0 2.9 3 0 0 3 3 3 1 PH domain RUN PF02759.14 KFP08474.1 - 8.8e-09 35.2 4.2 2e-08 34.0 2.0 2.2 2 0 0 2 2 2 1 RUN domain PH_9 PF15410.1 KFP08474.1 - 0.00018 21.6 0.0 0.14 12.2 0.0 2.9 3 0 0 3 3 3 2 Pleckstrin homology domain UBA PF00627.26 KFP08475.1 - 0.00063 19.5 0.1 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain FIVAR PF07554.8 KFP08475.1 - 0.096 12.9 0.2 0.26 11.5 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised Sugar-binding Domain Asp_protease PF09668.5 KFP08476.1 - 1.4e-39 134.4 1.0 1.7e-39 134.1 0.7 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KFP08476.1 - 7.6e-05 22.6 0.1 8.2e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KFP08476.1 - 0.00031 21.1 0.0 0.00081 19.8 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 KFP08476.1 - 0.012 15.4 0.1 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease DDOST_48kD PF03345.9 KFP08477.1 - 4.8e-149 496.4 0.0 5.4e-149 496.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DASH_Dad3 PF08656.5 KFP08478.1 - 0.021 14.4 2.1 0.035 13.7 1.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 TMF_TATA_bd PF12325.3 KFP08478.1 - 0.023 14.4 1.3 0.023 14.4 0.9 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding WEMBL PF05701.6 KFP08478.1 - 0.024 13.1 11.2 0.029 12.8 7.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Streptin-Immun PF11083.3 KFP08478.1 - 0.037 14.0 1.4 0.078 12.9 0.9 1.7 1 1 0 1 1 1 0 Lantibiotic streptin immunity protein DUF641 PF04859.7 KFP08478.1 - 0.085 12.6 6.7 0.056 13.1 3.3 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) HD_3 PF13023.1 KFP08478.1 - 0.11 12.2 4.0 0.056 13.1 1.5 1.5 1 1 1 2 2 2 0 HD domain DDE_Tnp_IS1595 PF12762.2 KFP08478.1 - 0.13 12.1 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 ISXO2-like transposase domain DUF745 PF05335.8 KFP08478.1 - 0.16 11.5 8.0 0.15 11.5 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) IncA PF04156.9 KFP08478.1 - 1.2 8.7 16.0 1.9 8.0 11.1 1.4 1 1 0 1 1 1 0 IncA protein CorA PF01544.13 KFP08478.1 - 1.5 7.7 7.0 1.9 7.4 4.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 KFP08478.1 - 2 8.5 8.3 2.9 7.9 5.5 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 KFP08478.1 - 2.1 8.3 12.9 0.36 10.8 5.7 1.9 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 KFP08478.1 - 3 6.8 15.7 3.8 6.4 10.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PID PF00640.18 KFP08479.1 - 2.8e-06 27.3 0.0 3.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Linker_histone PF00538.14 KFP08480.1 - 3.5e-43 145.5 0.4 1.4e-15 57.1 0.0 3.4 3 0 0 3 3 3 3 linker histone H1 and H5 family SDA1 PF05285.7 KFP08480.1 - 0.011 15.0 26.8 0.021 14.1 4.1 2.3 2 0 0 2 2 2 0 SDA1 Transglycosylas PF06737.9 KFP08480.1 - 0.023 14.9 1.9 5.5 7.3 0.0 3.5 4 0 0 4 4 4 0 Transglycosylase-like domain Daxx PF03344.10 KFP08480.1 - 0.039 12.4 29.2 0.058 11.8 7.6 2.2 2 0 0 2 2 2 0 Daxx Family DUF1510 PF07423.6 KFP08480.1 - 1.1 8.6 36.0 0.85 8.9 11.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 KFP08480.1 - 3.1 5.5 38.4 0.21 9.4 11.1 2.1 2 0 0 2 2 2 0 Nop14-like family Alk_phosphatase PF00245.15 KFP08481.1 - 4.6e-101 338.5 0.0 5.3e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase UCH PF00443.24 KFP08482.1 - 1.8e-39 135.4 2.5 1.8e-39 135.4 1.7 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFP08482.1 - 2e-20 73.4 16.2 1.2e-19 70.8 0.2 3.6 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFP08482.1 - 1.3e-09 38.3 0.3 0.0024 18.2 0.0 4.2 3 0 0 3 3 3 2 DUSP domain ubiquitin PF00240.18 KFP08482.1 - 1.4e-05 24.3 0.0 3.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Laminin_G_1 PF00054.18 KFP08483.1 - 6.8e-17 61.7 0.0 8e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.19 KFP08483.1 - 7.5e-16 58.3 0.0 8.7e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Laminin G domain CDP-OH_P_transf PF01066.16 KFP08484.1 - 1e-13 51.4 3.1 1e-13 51.4 2.2 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RNase_H PF00075.19 KFP08485.1 - 0.051 13.9 0.3 0.057 13.7 0.2 1.1 1 0 0 1 1 1 0 RNase H DUF2913 PF11140.3 KFP08485.1 - 0.21 10.8 1.9 0.23 10.7 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) zf-H2C2_2 PF13465.1 KFP08486.1 - 1.6e-25 88.1 25.0 1.2e-07 31.6 1.5 4.2 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08486.1 - 2e-16 59.2 34.4 7.3e-06 26.0 0.9 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08486.1 - 5.2e-11 42.0 35.4 8.3e-05 22.6 1.2 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-Di19 PF05605.7 KFP08486.1 - 0.00048 20.1 4.1 0.00048 20.1 2.8 3.3 2 1 2 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KFP08486.1 - 0.00066 19.4 21.0 0.27 11.1 0.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zinc_ribbon_2 PF13240.1 KFP08486.1 - 0.15 11.5 0.0 0.15 11.5 0.0 3.3 3 1 0 3 3 3 0 zinc-ribbon domain zf-C4_ClpX PF06689.8 KFP08486.1 - 0.17 11.4 5.2 1.5 8.3 0.2 2.5 2 0 0 2 2 2 0 ClpX C4-type zinc finger Zn-ribbon_8 PF09723.5 KFP08486.1 - 0.17 11.8 18.3 7.1 6.6 2.3 4.0 2 1 1 3 3 3 0 Zinc ribbon domain PyrI_C PF02748.10 KFP08486.1 - 0.4 10.1 0.1 0.4 10.1 0.1 3.1 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF164 PF02591.10 KFP08486.1 - 1.6 8.6 10.2 2.2 8.1 0.6 3.3 2 1 1 3 3 3 0 Putative zinc ribbon domain zf-C2HC_2 PF13913.1 KFP08486.1 - 1.8 8.3 7.6 14 5.4 0.0 4.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type IBR PF01485.16 KFP08486.1 - 2.1 8.3 15.8 64 3.5 9.1 3.2 1 1 1 2 2 2 0 IBR domain zf-AN1 PF01428.11 KFP08486.1 - 3.4 7.6 10.7 6.2 6.7 0.1 3.7 3 1 0 3 3 3 0 AN1-like Zinc finger zf-C2H2_2 PF12756.2 KFP08486.1 - 3.6 7.7 17.9 0.21 11.6 1.1 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-MIZ PF02891.15 KFP08486.1 - 5.2 6.6 11.4 0.32 10.5 2.4 2.7 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf-C2H2_jaz PF12171.3 KFP08486.1 - 7.9 6.7 18.8 1.4 9.1 1.4 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding SAM_1 PF00536.25 KFP08487.1 - 3.8e-19 68.6 0.0 5.6e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP08487.1 - 2.2e-09 37.0 0.0 3.2e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFP08487.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SCHIP-1 PF10148.4 KFP08487.1 - 0.051 12.9 1.9 0.071 12.4 1.3 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 zf-FCS PF06467.9 KFP08487.1 - 0.082 12.5 2.8 0.63 9.7 1.9 2.2 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Sox_C_TAD PF12067.3 KFP08488.1 - 3.9 7.5 20.0 5.7 7.0 13.8 1.3 1 1 0 1 1 1 0 Sox C-terminal transactivation domain Sugar_tr PF00083.19 KFP08489.1 - 2.6e-155 517.4 27.0 3.2e-155 517.1 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFP08489.1 - 9.7e-20 70.5 33.3 1.3e-17 63.6 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFP08489.1 - 4.8e-05 21.9 20.4 0.00058 18.3 4.8 3.5 2 1 1 3 3 3 2 MFS/sugar transport protein 60KD_IMP PF02096.15 KFP08489.1 - 0.005 16.5 1.1 0.005 16.5 0.8 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein Syndecan PF01034.15 KFP08489.1 - 0.27 10.9 2.8 13 5.5 0.5 3.2 2 0 0 2 2 2 0 Syndecan domain TPR_12 PF13424.1 KFP08490.1 - 1.4e-09 37.7 8.3 0.00077 19.3 0.3 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFP08490.1 - 0.0014 18.1 3.4 13 5.5 0.1 4.1 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 KFP08490.1 - 0.0062 16.3 8.6 4.3 7.5 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFP08490.1 - 0.011 15.6 3.4 42 4.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFP08490.1 - 0.088 12.4 1.7 5.1 6.8 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFP08490.1 - 0.14 12.2 2.1 2.7 8.1 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 S-AdoMet_synt_C PF02773.11 KFP08491.1 - 2.9e-72 240.8 0.0 4.4e-72 240.2 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KFP08491.1 - 1.5e-42 144.3 0.0 2.5e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KFP08491.1 - 8.5e-40 135.0 0.1 1.8e-39 133.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 KFP08491.1 - 0.057 12.5 0.0 2.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Amidinotransferase Phosphodiest PF01663.17 KFP08492.1 - 1.2e-15 57.7 0.2 6.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFP08492.1 - 0.0093 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily IncA PF04156.9 KFP08492.1 - 0.34 10.4 4.7 0.11 12.0 0.4 2.4 2 1 1 3 3 3 0 IncA protein TraB PF01963.12 KFP08493.1 - 4.6e-08 32.8 0.0 4.2e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 TraB family RVT_1 PF00078.22 KFP08494.1 - 1.7e-21 76.6 0.0 2.8e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KFP08494.1 - 0.053 12.4 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TraB PF01963.12 KFP08495.1 - 9.1e-11 41.6 0.0 9.6e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 TraB family Lipase_GDSL_2 PF13472.1 KFP08496.1 - 3.1e-05 24.1 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 KFP08497.1 - 9.3e-24 83.7 23.2 1.1e-23 83.5 16.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C3HC4 PF00097.20 KFP08498.1 - 3.3e-09 36.2 9.3 3.3e-09 36.2 6.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP08498.1 - 8.9e-09 35.2 8.6 8.9e-09 35.2 5.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFP08498.1 - 2.6e-08 33.5 8.6 2.6e-08 33.5 6.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFP08498.1 - 4.3e-06 26.2 8.0 4.3e-06 26.2 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP08498.1 - 3e-05 23.6 9.3 3e-05 23.6 6.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFP08498.1 - 0.0014 18.6 6.2 0.0014 18.6 4.3 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KFP08498.1 - 0.0015 18.3 8.7 0.0015 18.3 6.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFP08498.1 - 0.0058 16.1 6.2 0.0058 16.1 4.3 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain CDC45 PF02724.9 KFP08498.1 - 0.015 13.3 0.0 0.015 13.3 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-Nse PF11789.3 KFP08498.1 - 0.017 14.6 3.9 0.03 13.8 2.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFP08498.1 - 0.02 14.5 3.6 0.064 12.9 2.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger GAGA PF09237.6 KFP08498.1 - 0.026 14.1 0.1 0.082 12.5 0.0 1.8 1 0 0 1 1 1 0 GAGA factor BAF1_ABF1 PF04684.8 KFP08498.1 - 0.064 12.0 1.9 0.085 11.6 1.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CobT PF06213.7 KFP08498.1 - 0.16 11.0 3.9 0.22 10.6 2.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3337 PF11816.3 KFP08498.1 - 0.18 11.1 5.1 0.5 9.7 2.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3337) zf-Apc11 PF12861.2 KFP08498.1 - 0.31 10.9 3.6 0.81 9.5 2.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 KFP08498.1 - 0.45 10.3 9.1 0.37 10.6 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 KFP08498.1 - 0.86 9.4 7.4 0.34 10.7 3.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Synaphin PF05835.7 KFP08499.1 - 1.6e-40 138.5 17.3 1.7e-40 138.3 12.0 1.0 1 0 0 1 1 1 1 Synaphin protein DUF4407 PF14362.1 KFP08499.1 - 1.3 7.9 8.4 1.6 7.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 KFP08499.1 - 1.7 6.8 10.0 1.7 6.8 6.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 KFP08499.1 - 2.8 7.2 20.8 3.9 6.8 14.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Stm1_N PF09598.5 KFP08499.1 - 6.1 7.6 11.1 9.2e+02 0.6 7.7 2.2 1 1 0 1 1 1 0 Stm1 APG6 PF04111.7 KFP08499.1 - 8.2 5.3 9.8 9.8 5.1 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Epimerase_2 PF02350.14 KFP08500.1 - 2.9e-73 246.6 0.1 4.6e-73 245.9 0.1 1.2 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase ROK PF00480.15 KFP08500.1 - 1.7e-38 132.2 1.6 7.6e-38 130.1 0.6 2.3 2 0 0 2 2 2 1 ROK family BcrAD_BadFG PF01869.15 KFP08500.1 - 6.2e-05 22.4 1.6 0.2 10.9 0.2 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 KFP08500.1 - 0.002 17.4 0.0 0.0051 16.1 0.0 1.6 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 KFP08500.1 - 0.0036 16.6 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DRTGG PF07085.7 KFP08500.1 - 0.0036 16.8 0.2 0.012 15.2 0.1 1.9 1 0 0 1 1 1 1 DRTGG domain Glucokinase PF02685.11 KFP08500.1 - 0.19 10.4 0.0 0.19 10.4 0.0 2.4 3 0 0 3 3 3 0 Glucokinase Clathrin_lg_ch PF01086.12 KFP08501.1 - 1.1e-51 175.9 8.8 1.4e-51 175.5 6.1 1.1 1 0 0 1 1 1 1 Clathrin light chain CENP-Q PF13094.1 KFP08501.1 - 0.0053 16.7 10.2 0.012 15.6 7.1 1.5 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Myc-LZ PF02344.10 KFP08501.1 - 0.013 15.0 3.7 0.023 14.3 2.5 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain DUF2265 PF10023.4 KFP08501.1 - 0.058 12.5 3.1 0.065 12.3 2.1 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) OmpH PF03938.9 KFP08501.1 - 0.37 10.7 7.0 0.54 10.1 4.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YgaB PF14182.1 KFP08501.1 - 0.59 10.4 4.5 1.2 9.4 3.1 1.5 1 0 0 1 1 1 0 YgaB-like protein FadA PF09403.5 KFP08501.1 - 1.1 9.3 9.3 1.9 8.4 6.5 1.5 1 1 0 1 1 1 0 Adhesion protein FadA TBCA PF02970.11 KFP08501.1 - 3.4 7.8 10.5 8.6 6.5 6.5 2.2 2 1 0 2 2 2 0 Tubulin binding cofactor A APG6 PF04111.7 KFP08501.1 - 4.7 6.1 9.0 6.2 5.7 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NeuB PF03102.9 KFP08502.1 - 2.2e-78 262.7 0.0 2.6e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 NeuB family SAF PF08666.7 KFP08502.1 - 1.4e-08 35.0 0.2 3e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 SAF domain SAF_2 PF13144.1 KFP08502.1 - 0.0031 17.0 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 SAF-like DUF849 PF05853.7 KFP08502.1 - 0.024 13.5 0.1 0.54 9.0 0.0 2.2 1 1 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) zf-RING_2 PF13639.1 KFP08503.1 - 4.1e-10 39.3 4.0 8.8e-10 38.2 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFP08503.1 - 5.1e-05 23.2 1.8 0.00014 21.8 1.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFP08503.1 - 5.7e-05 22.6 3.5 0.00011 21.8 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP08503.1 - 0.00043 20.2 4.3 0.001 19.0 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP08503.1 - 0.0024 17.5 3.2 0.0056 16.3 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 KFP08503.1 - 0.19 11.6 2.9 0.43 10.5 2.0 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KFP08503.1 - 0.76 9.8 4.6 1.4 8.9 3.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 KFP08503.1 - 1.3 8.7 9.9 0.042 13.5 2.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFP08503.1 - 2.8 7.8 8.3 0.074 12.8 0.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger SH2 PF00017.19 KFP08504.1 - 8.4e-18 63.9 0.1 1.2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Ank_2 PF12796.2 KFP08505.1 - 4.4e-74 244.8 14.8 6e-24 84.1 0.6 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFP08505.1 - 2.4e-60 197.4 15.0 4.7e-08 32.4 0.0 8.9 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 KFP08505.1 - 4.8e-43 140.8 12.4 1.3e-06 28.0 0.0 10.2 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KFP08505.1 - 5.2e-41 138.3 6.2 6e-10 39.3 0.0 7.2 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP08505.1 - 3.3e-40 135.1 11.3 2.2e-09 37.2 0.2 8.1 4 2 5 9 9 9 7 Ankyrin repeats (many copies) TPR_12 PF13424.1 KFP08505.1 - 1.9e-05 24.5 0.1 0.009 15.9 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFP08505.1 - 0.019 14.8 0.7 0.36 10.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFP08505.1 - 0.12 12.3 0.1 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4497 PF14924.1 KFP08506.1 - 0.03 14.6 0.2 0.03 14.6 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4497) Baculo_PEP_C PF04513.7 KFP08506.1 - 0.047 13.5 0.7 0.091 12.5 0.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KFP08506.1 - 0.051 13.8 1.2 0.13 12.5 0.9 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prenyltrans PF00432.16 KFP08507.1 - 7.4e-32 108.5 12.2 7.2e-10 38.2 0.0 7.4 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFP08507.1 - 1.2e-10 41.7 0.0 0.00018 21.9 0.0 3.5 2 1 2 4 4 4 3 Prenyltransferase-like zf-B_box PF00643.19 KFP08508.1 - 2.4e-07 30.5 7.7 2.4e-07 30.5 5.3 4.4 4 1 0 4 4 4 2 B-box zinc finger SPRY PF00622.23 KFP08508.1 - 3e-06 27.3 0.0 9.2e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 SPRY domain zf-C3HC4 PF00097.20 KFP08508.1 - 6.3e-06 25.7 4.4 6.3e-06 25.7 3.0 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFP08508.1 - 3e-05 23.9 5.2 3e-05 23.9 3.6 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFP08508.1 - 3e-05 23.8 4.9 3e-05 23.8 3.4 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING fn3 PF00041.16 KFP08508.1 - 3.7e-05 23.7 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.1 KFP08508.1 - 0.00042 19.9 3.5 0.00042 19.9 2.4 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFP08508.1 - 0.00043 19.9 2.9 0.00043 19.9 2.0 4.2 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFP08508.1 - 0.00089 18.9 6.1 0.00089 18.9 4.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Mss4 PF04421.8 KFP08508.1 - 1.3 8.8 4.8 4.4 7.2 3.3 1.8 1 0 0 1 1 1 0 Mss4 protein DOR PF14839.1 KFP08509.1 - 9 5.9 7.3 8.9 5.9 5.1 1.1 1 0 0 1 1 1 0 DOR family CaMBD PF02888.11 KFP08510.1 - 6.3e-36 122.0 9.2 6.3e-36 122.0 6.4 2.1 2 0 0 2 2 2 1 Calmodulin binding domain SK_channel PF03530.9 KFP08510.1 - 1.3e-35 121.7 0.9 1.3e-35 121.7 0.6 2.2 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.11 KFP08510.1 - 6.1e-13 48.2 3.9 6.1e-13 48.2 2.7 2.0 2 0 0 2 2 2 1 Ion channel Med9 PF07544.8 KFP08510.1 - 0.0063 16.2 0.2 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 KFP08510.1 - 1.3 8.7 11.6 9.1 6.1 4.6 3.2 1 1 1 2 2 2 0 Prefoldin subunit YTH PF04146.10 KFP08511.1 - 1.4e-46 157.6 0.2 3.4e-46 156.3 0.1 1.7 1 0 0 1 1 1 1 YT521-B-like domain HA2 PF04408.18 KFP08511.1 - 1.8e-20 72.8 0.1 5.5e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFP08511.1 - 1.2e-14 53.9 0.0 2.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KFP08511.1 - 4.9e-13 48.9 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KFP08511.1 - 1.7e-10 40.6 0.2 3.4e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.2 KFP08511.1 - 2e-10 40.8 0.0 5.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFP08511.1 - 3.5e-05 23.3 0.0 0.0011 18.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.1 KFP08511.1 - 0.00026 21.1 0.1 0.0015 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 KFP08511.1 - 0.0013 17.8 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 KaiC Ank_4 PF13637.1 KFP08511.1 - 0.0015 19.0 0.0 0.027 14.9 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP08511.1 - 0.0048 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PhoH PF02562.11 KFP08511.1 - 0.0074 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_29 PF13555.1 KFP08511.1 - 0.013 15.0 0.0 0.036 13.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KFP08511.1 - 0.013 15.8 1.5 0.029 14.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KFP08511.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1651 PF07864.6 KFP08511.1 - 0.03 14.4 1.0 3.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1651) FtsK_SpoIIIE PF01580.13 KFP08511.1 - 0.044 13.2 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KFP08511.1 - 0.058 13.1 0.3 0.33 10.7 0.0 2.4 3 0 0 3 3 3 0 Part of AAA domain SRP54 PF00448.17 KFP08511.1 - 0.067 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MCC-bdg_PDZ PF10506.4 KFP08512.1 - 2e-59 197.2 40.1 7.6e-29 99.3 4.8 6.3 6 0 0 6 6 6 3 PDZ domain of MCC-2 bdg protein for Usher syndrome ERM PF00769.14 KFP08512.1 - 1.2e-05 24.9 70.2 0.00016 21.2 7.9 5.0 4 1 0 4 4 4 3 Ezrin/radixin/moesin family APG6 PF04111.7 KFP08512.1 - 0.011 14.7 0.8 0.011 14.7 0.6 5.6 4 1 2 6 6 6 0 Autophagy protein Apg6 DUF1359 PF07097.6 KFP08512.1 - 0.14 12.2 8.3 1 9.4 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1359) Myosin_tail_1 PF01576.14 KFP08512.1 - 5.4 4.5 78.8 0.053 11.2 12.0 4.2 3 1 1 4 4 4 0 Myosin tail DCP2 PF05026.8 KFP08513.1 - 3.3e-25 87.7 0.2 3.9e-23 81.1 0.1 3.2 2 1 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 KFP08513.1 - 3.8e-16 58.9 0.0 7.7e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TB2_DP1_HVA22 PF03134.14 KFP08514.1 - 1.1e-27 95.6 1.7 1.3e-27 95.4 1.2 1.0 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SRP19 PF01922.12 KFP08515.1 - 8.4e-26 90.3 0.1 1e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein APC_basic PF05956.6 KFP08516.1 - 5.2e-111 371.2 71.4 5.2e-111 371.2 49.5 8.3 8 2 1 9 9 9 1 APC basic domain EB1_binding PF05937.6 KFP08516.1 - 1.7e-85 285.7 22.2 1.7e-85 285.7 15.4 8.1 6 3 1 9 9 9 1 EB-1 Binding Domain APC_crr PF05923.7 KFP08516.1 - 1.6e-66 217.5 47.6 2.8e-11 42.5 1.4 9.4 8 0 0 8 8 8 7 APC cysteine-rich region Arm PF00514.18 KFP08516.1 - 3.2e-30 102.8 14.3 3.1e-07 29.9 0.3 6.9 6 0 0 6 6 6 6 Armadillo/beta-catenin-like repeat Suppressor_APC PF11414.3 KFP08516.1 - 6.1e-28 96.4 6.1 6.1e-28 96.4 4.2 2.9 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein APC_15aa PF05972.6 KFP08516.1 - 3.8e-24 82.9 26.3 7.3e-06 25.6 0.1 6.0 6 0 0 6 6 6 4 APC 15 residue motif SAMP PF05924.6 KFP08516.1 - 1e-22 78.3 8.4 2.6e-08 32.6 0.0 4.1 3 0 0 3 3 3 3 SAMP Motif HALZ PF02183.13 KFP08516.1 - 0.67 9.7 12.5 0.038 13.7 1.8 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper FERM_M PF00373.13 KFP08517.1 - 1.3e-19 70.5 0.1 1.3e-19 70.5 0.1 2.0 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.5 KFP08517.1 - 5.4e-18 64.8 0.1 4.3e-17 61.9 0.0 2.4 3 0 0 3 3 3 1 FERM N-terminal domain FERM_C PF09380.5 KFP08517.1 - 4.9e-17 61.9 0.7 9.4e-17 61.0 0.5 1.5 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.6 KFP08517.1 - 4.3e-12 45.6 2.9 4.3e-12 45.6 2.0 2.9 3 0 0 3 3 3 1 FERM adjacent (FA) Alveol-reg_P311 PF11092.3 KFP08518.1 - 3.6e-31 106.9 0.1 3.8e-31 106.8 0.1 1.0 1 0 0 1 1 1 1 Neuronal protein 3.1 (p311) START PF01852.14 KFP08519.1 - 2.7e-16 59.5 0.0 2.8e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 START domain Pkinase PF00069.20 KFP08520.1 - 7.6e-46 156.3 0.0 8.5e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08520.1 - 1.9e-15 56.6 0.0 2.1e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP08520.1 - 0.0018 17.3 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Utp21 PF04192.7 KFP08521.1 - 1.2e-70 237.2 0.0 1.9e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KFP08521.1 - 1.5e-29 100.7 6.9 9.1e-10 38.0 0.0 9.1 10 0 0 10 10 10 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFP08521.1 - 0.00098 17.5 0.0 0.0018 16.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KFP08521.1 - 0.019 13.7 2.4 1.2 7.8 0.0 3.3 2 2 1 3 3 3 0 Nup133 N terminal like Utp12 PF04003.7 KFP08521.1 - 0.027 14.3 3.3 0.068 13.0 1.8 1.9 2 0 0 2 2 2 0 Dip2/Utp12 Family RTC PF01137.16 KFP08521.1 - 0.042 12.6 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase SGL PF08450.7 KFP08521.1 - 0.12 11.7 0.0 0.66 9.3 0.0 2.2 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Mito_carr PF00153.22 KFP08522.1 - 4.3e-19 68.0 0.1 4.3e-11 42.3 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_38 PF01074.17 KFP08523.1 - 5.8e-97 324.2 4.9 9.6e-97 323.5 3.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFP08523.1 - 1.7e-63 215.0 0.1 3e-63 214.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFP08523.1 - 1.2e-26 92.6 0.0 2.6e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Polysacc_deac_1 PF01522.16 KFP08523.1 - 0.08 12.5 0.0 0.26 10.9 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide deacetylase zf-RING_2 PF13639.1 KFP08525.1 - 1.9e-12 46.7 12.9 4.2e-12 45.6 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFP08525.1 - 4.8e-08 32.8 9.0 1e-07 31.8 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFP08525.1 - 9e-07 28.4 8.4 1.9e-06 27.4 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFP08525.1 - 1.6e-06 27.6 8.6 3e-06 26.8 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFP08525.1 - 3e-06 27.2 6.8 3e-06 27.2 4.7 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFP08525.1 - 2.9e-05 23.7 9.9 6.1e-05 22.6 6.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFP08525.1 - 0.00029 20.6 5.3 0.00058 19.6 3.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KFP08525.1 - 0.82 9.7 7.2 1.9 8.5 5.0 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFP08525.1 - 1.2 9.1 8.9 5.2 7.0 6.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KFP08525.1 - 1.7 8.2 7.7 5 6.7 5.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase_Tyr PF07714.12 KFP08526.1 - 2e-102 341.7 0.1 9.8e-102 339.4 0.0 2.3 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.20 KFP08526.1 - 8e-53 179.2 0.0 2.8e-52 177.4 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 KFP08526.1 - 2.3e-22 78.5 0.0 8e-22 76.8 0.0 2.0 1 0 0 1 1 1 1 SH2 domain FCH PF00611.18 KFP08526.1 - 4.5e-17 62.0 1.1 4.5e-17 62.0 0.7 3.7 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain LRR_6 PF13516.1 KFP08528.1 - 1e-15 55.9 6.3 1.2 9.4 0.1 10.3 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.2 KFP08528.1 - 1e-07 31.3 4.9 0.2 11.3 0.4 6.3 3 3 3 6 6 6 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KFP08528.1 - 1.4e-06 27.9 3.5 3.4e-06 26.6 2.4 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KFP08528.1 - 0.00023 20.8 8.1 0.13 12.0 1.0 5.0 3 2 2 5 5 5 2 Leucine rich repeat F-box PF00646.28 KFP08528.1 - 0.002 17.7 2.6 0.002 17.7 1.8 2.6 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 KFP08528.1 - 0.065 13.3 10.3 15 6.1 0.0 6.7 5 2 0 5 5 5 0 Leucine Rich Repeat Aldedh PF00171.17 KFP08528.1 - 0.12 10.6 0.0 0.24 9.6 0.0 1.4 2 0 0 2 2 2 0 Aldehyde dehydrogenase family LRR_7 PF13504.1 KFP08528.1 - 0.16 12.2 12.0 2.1 8.8 0.0 6.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_2 PF07723.8 KFP08528.1 - 0.57 10.7 3.7 7.2 7.2 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat Ephrin PF00812.12 KFP08529.1 - 9.5e-47 158.1 0.2 1.2e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Ephrin PWWP PF00855.12 KFP08530.1 - 2e-12 47.1 0.5 2e-12 47.1 0.3 4.3 3 2 0 3 3 3 1 PWWP domain Bromodomain PF00439.20 KFP08530.1 - 7.8e-12 44.9 0.3 2e-11 43.6 0.2 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 KFP08530.1 - 0.00011 21.8 9.3 0.00011 21.8 6.4 4.5 3 2 1 4 4 4 1 PHD-finger zf-MYND PF01753.13 KFP08530.1 - 0.0022 17.8 21.8 0.0022 17.8 15.1 4.1 3 1 0 3 3 3 1 MYND finger Spore_III_AB PF09548.5 KFP08530.1 - 0.41 10.3 4.5 1 9.0 3.1 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Mitofilin PF09731.4 KFP08530.1 - 5.3 5.5 23.2 9.8 4.6 16.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AMP-binding PF00501.23 KFP08531.1 - 2e-74 250.5 0.1 1.5e-53 181.7 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 KFP08531.1 - 6.9e-06 26.6 0.2 1.2e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 DMAP1-binding Domain La PF05383.12 KFP08532.1 - 2.2e-18 65.7 0.2 4.2e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_5 PF13893.1 KFP08532.1 - 0.00036 20.3 0.1 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP08532.1 - 0.00039 20.3 0.0 0.0009 19.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NOG1 PF06858.9 KFP08533.1 - 5.9e-30 102.9 0.1 1.3e-29 101.8 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 KFP08533.1 - 5.8e-24 83.5 8.2 2.9e-23 81.2 3.9 2.8 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 KFP08533.1 - 8e-20 70.9 0.0 3.3e-19 68.9 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFP08533.1 - 5.1e-11 42.0 0.0 1.2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFP08533.1 - 6.7e-08 33.0 0.0 4.2e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 KFP08533.1 - 1.7e-05 24.2 0.0 5.7e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Ras family AIG1 PF04548.11 KFP08533.1 - 0.0001 21.4 0.4 0.00097 18.2 0.0 2.7 3 0 0 3 3 3 1 AIG1 family Gtr1_RagA PF04670.7 KFP08533.1 - 0.00045 19.4 0.2 0.0069 15.5 0.0 2.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KFP08533.1 - 0.0016 17.6 0.6 0.041 13.0 0.0 3.1 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KFP08533.1 - 0.0051 16.6 6.6 0.32 10.7 0.0 3.4 2 2 1 3 3 2 2 Dynamin family DUF258 PF03193.11 KFP08533.1 - 0.022 13.9 0.0 0.16 11.1 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFP08533.1 - 0.039 13.4 0.0 9 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 KFP08533.1 - 0.041 13.5 0.3 0.36 10.5 0.0 2.8 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B NUDIX PF00293.23 KFP08534.1 - 1e-25 89.9 0.0 1.3e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.27 KFP08535.1 - 5.4e-38 127.5 23.7 2.2e-08 33.6 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat HALZ PF02183.13 KFP08535.1 - 0.003 17.2 0.5 0.0061 16.2 0.4 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 KFP08535.1 - 0.054 13.8 1.2 0.12 12.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIVA PF05103.8 KFP08535.1 - 0.081 12.9 0.5 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 DivIVA protein A_deamin PF02137.13 KFP08536.1 - 2e-115 385.8 0.0 2.7e-115 385.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.20 KFP08536.1 - 1.3e-25 89.7 0.2 5.4e-12 46.1 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFP08536.1 - 0.0045 17.2 0.8 1.4 9.2 0.0 2.9 2 1 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 PFK PF00365.15 KFP08537.1 - 4.2e-194 642.7 9.6 3.1e-135 449.6 2.7 2.1 2 0 0 2 2 2 2 Phosphofructokinase M16C_assoc PF08367.6 KFP08538.1 - 7e-85 283.8 0.0 1.2e-84 283.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KFP08538.1 - 1.8e-30 105.9 0.0 8e-21 74.5 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFP08538.1 - 2e-09 37.3 0.3 7.1e-05 22.5 0.0 3.7 5 0 0 5 5 5 2 Insulinase (Peptidase family M16) DUF3007 PF11460.3 KFP08538.1 - 0.11 12.5 0.5 0.31 11.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) zf-C2H2 PF00096.21 KFP08539.1 - 1.1e-12 47.4 31.8 0.00019 21.6 6.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFP08539.1 - 8e-11 41.6 13.3 8.5e-07 28.9 4.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFP08539.1 - 1.7e-07 31.0 29.5 0.0097 16.1 1.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KFP08539.1 - 0.35 11.1 0.1 0.35 11.1 0.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KFP08539.1 - 3.4 7.9 10.0 11 6.2 1.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Frizzled PF01534.12 KFP08541.1 - 1.1e-84 283.9 5.9 7.6e-62 208.9 1.2 2.1 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Fz PF01392.17 KFP08541.1 - 2.1e-34 118.3 2.2 3.5e-34 117.6 1.5 1.3 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.6 KFP08541.1 - 0.0011 17.9 2.2 0.0018 17.2 1.5 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KFP08541.1 - 0.041 13.0 3.3 0.023 13.8 0.4 1.9 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Cyclin_N PF00134.18 KFP08542.1 - 1.4e-14 53.7 0.2 3e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFP08542.1 - 7.2e-13 49.2 0.1 1.1e-12 48.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin bZIP_1 PF00170.16 KFP08543.1 - 2.2e-20 72.3 12.6 3.5e-20 71.7 8.5 1.6 2 0 0 2 2 2 1 bZIP transcription factor pKID PF02173.12 KFP08543.1 - 1.1e-18 66.1 1.4 2.7e-18 64.8 0.9 1.7 1 0 0 1 1 1 1 pKID domain bZIP_2 PF07716.10 KFP08543.1 - 1.2e-07 31.3 10.8 2e-07 30.6 7.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFP08543.1 - 0.0019 18.4 6.2 0.0035 17.5 4.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Cullin PF00888.17 KFP08544.1 - 7e-192 639.0 27.6 7e-192 639.0 19.2 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KFP08544.1 - 4.1e-28 96.9 3.5 4.1e-28 96.9 2.5 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Rio2_N PF09202.6 KFP08544.1 - 0.0075 16.3 0.6 0.044 13.8 0.1 2.5 2 0 0 2 2 2 1 Rio2, N-terminal SCAN PF02023.12 KFP08544.1 - 0.031 13.7 0.3 5.5 6.5 0.0 3.1 2 0 0 2 2 2 0 SCAN domain HTH_34 PF13601.1 KFP08544.1 - 0.05 13.6 0.6 0.42 10.6 0.2 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF3534 PF12053.3 KFP08545.1 - 9.5e-50 168.2 0.1 9.5e-50 168.2 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3534) PDZ PF00595.19 KFP08545.1 - 6.6e-38 128.7 6.1 2e-15 56.7 0.1 3.7 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP08545.1 - 8.5e-15 54.4 0.8 2.3e-06 27.4 0.1 3.9 3 1 0 3 3 3 3 PDZ domain Yae1_N PF09811.4 KFP08548.1 - 1.6e-08 33.9 23.5 8.8e-05 21.9 8.1 3.0 2 1 0 2 2 2 2 Essential protein Yae1, N terminal CUB PF00431.15 KFP08549.1 - 2.5e-64 214.1 0.0 2.5e-32 111.2 0.0 2.7 2 0 0 2 2 2 2 CUB domain F5_F8_type_C PF00754.20 KFP08549.1 - 9.7e-53 177.4 2.3 3.6e-26 91.5 0.1 2.4 2 0 0 2 2 2 2 F5/8 type C domain MAM PF00629.18 KFP08549.1 - 4.9e-39 133.6 1.1 1.1e-38 132.4 0.8 1.6 1 0 0 1 1 1 1 MAM domain DUF3481 PF11980.3 KFP08549.1 - 3e-29 100.6 0.1 1.1e-28 98.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3481) Integrin_beta PF00362.13 KFP08550.1 - 4.7e-192 638.5 0.6 4.7e-192 638.5 0.4 2.0 2 0 0 2 2 2 1 Integrin, beta chain Integrin_B_tail PF07965.7 KFP08550.1 - 1.5e-23 83.0 7.9 1.5e-23 83.0 5.5 4.5 6 1 1 7 7 7 1 Integrin beta tail domain Integrin_b_cyt PF08725.6 KFP08550.1 - 1.5e-10 40.2 0.6 3e-10 39.2 0.4 1.5 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain EGF_2 PF07974.8 KFP08550.1 - 1.8e-09 37.6 59.3 4.9e-06 26.6 11.2 7.3 6 1 1 7 7 7 3 EGF-like domain E_Pc_C PF06752.7 KFP08551.1 - 4.5e-97 324.0 29.0 9.9e-97 322.9 20.1 1.6 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus EPL1 PF10513.4 KFP08551.1 - 1.5e-17 64.2 1.1 1.5e-17 64.2 0.8 3.7 4 1 0 4 4 4 2 Enhancer of polycomb-like Kinesin PF00225.18 KFP08552.1 - 8.8e-111 369.8 2.7 8.8e-111 369.8 1.9 2.8 3 1 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 KFP08552.1 - 0.0032 16.6 26.5 0.055 12.6 4.7 3.9 2 1 1 3 3 3 3 Reovirus sigma C capsid protein RhoGAP PF00620.22 KFP08553.1 - 8.8e-50 168.2 1.0 1.6e-49 167.4 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.1 KFP08553.1 - 2.3e-10 39.8 0.6 5.1e-10 38.7 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFP08553.1 - 8.6e-08 32.3 0.4 3.5e-07 30.3 0.2 2.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFP08553.1 - 2.1e-07 31.0 0.2 6.9e-07 29.4 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.23 KFP08553.1 - 1.3e-06 27.7 3.8 6.3e-06 25.4 0.8 2.6 2 0 0 2 2 2 1 SH3 domain WW PF00397.21 KFP08553.1 - 0.00022 21.0 4.8 0.00022 21.0 3.3 4.2 3 1 1 4 4 4 2 WW domain zf-H2C2_2 PF13465.1 KFP08554.1 - 7.2e-34 114.4 55.6 1.1e-08 34.9 1.6 7.9 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08554.1 - 5.2e-23 79.9 70.1 0.00029 20.9 3.4 7.7 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08554.1 - 5.8e-17 60.6 54.5 0.0016 18.6 1.0 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP08554.1 - 1.7e-11 43.9 55.5 0.0014 18.6 0.9 7.8 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFP08554.1 - 7.2e-09 35.5 45.8 0.025 14.7 0.9 6.8 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFP08554.1 - 9.4e-09 35.2 25.2 3.8e-07 30.1 1.0 3.8 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding Homeobox PF00046.24 KFP08554.1 - 1.4e-05 24.6 0.0 4.2e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_6 PF13912.1 KFP08554.1 - 0.00011 21.9 57.6 0.052 13.4 0.5 7.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFP08554.1 - 0.44 10.6 45.1 0.056 13.5 0.7 6.9 3 2 3 6 6 6 0 C2H2 type zinc-finger (2 copies) DUF1610 PF07754.6 KFP08554.1 - 2.8 8.1 11.4 5.8 7.1 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-H2C2_2 PF13465.1 KFP08555.1 - 6.3e-09 35.6 25.3 0.00013 22.0 2.0 4.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08555.1 - 0.014 15.6 42.5 0.017 15.4 2.8 5.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08555.1 - 0.1 13.0 49.2 0.67 10.4 1.6 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger Gelsolin PF00626.17 KFP08556.1 - 2.3e-20 72.0 1.0 8.9e-06 25.3 0.0 5.7 5 0 0 5 5 5 4 Gelsolin repeat VHP PF02209.14 KFP08556.1 - 6.7e-14 51.2 0.1 6.7e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 Villin headpiece domain JCAD PF15351.1 KFP08557.1 - 0 1773.4 63.2 0 1773.2 43.8 1.0 1 0 0 1 1 1 1 Junctional protein associated with coronary artery disease PAP_assoc PF03828.14 KFP08558.1 - 2.6e-08 33.6 0.2 6.9e-08 32.3 0.2 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase RRM_5 PF13893.1 KFP08558.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_NucTransf2 PF09249.6 KFP08558.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain Pkinase PF00069.20 KFP08559.1 - 1.5e-52 178.2 0.0 2.3e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08559.1 - 2.5e-25 89.0 0.0 5.7e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP08559.1 - 0.039 13.6 0.1 0.15 11.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFP08559.1 - 0.084 11.8 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 KFP08559.1 - 0.13 11.6 0.2 0.34 10.2 0.0 1.7 1 1 1 2 2 2 0 RIO1 family FA_desaturase PF00487.19 KFP08561.1 - 3.9e-15 55.9 9.8 4.4e-15 55.8 6.3 1.3 2 0 0 2 2 2 1 Fatty acid desaturase wnt PF00110.14 KFP08562.1 - 1.6e-107 359.3 19.7 1.9e-107 359.0 13.7 1.0 1 0 0 1 1 1 1 wnt family WD40 PF00400.27 KFP08563.1 - 6.1e-14 51.2 8.3 5.3e-06 26.1 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.2 KFP08563.1 - 4.2e-06 26.7 0.3 1.9e-05 24.5 0.2 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 KFP08563.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Prp18 domain NDUF_B8 PF05821.6 KFP08564.1 - 2.1e-78 262.0 7.0 2.3e-78 261.9 4.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Cupin_8 PF13621.1 KFP08565.1 - 6.5e-42 143.7 0.4 9.1e-42 143.2 0.3 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFP08565.1 - 1.7e-07 30.8 0.6 2.2e-07 30.4 0.1 1.5 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 KFP08565.1 - 0.029 14.6 0.2 0.16 12.2 0.1 2.2 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 KFP08565.1 - 0.042 13.3 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Pax2_C PF12403.3 KFP08567.1 - 1.6e-45 153.5 6.8 3.2e-45 152.5 4.7 1.5 1 0 0 1 1 1 1 Paired-box protein 2 C terminal Homeobox PF00046.24 KFP08567.1 - 0.0048 16.4 0.1 0.0095 15.5 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain CUE PF02845.11 KFP08568.1 - 0.048 13.1 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 CUE domain DUF2992 PF11208.3 KFP08568.1 - 0.052 13.4 1.2 0.11 12.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) F-box PF00646.28 KFP08569.1 - 2.5e-06 26.9 6.1 3.2e-05 23.4 0.4 2.9 2 0 0 2 2 2 2 F-box domain LRR_6 PF13516.1 KFP08569.1 - 3.1e-05 23.5 5.1 23 5.4 0.0 6.5 7 0 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.1 KFP08569.1 - 3.5e-05 23.4 4.5 0.25 11.1 0.1 4.6 3 1 3 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 KFP08569.1 - 0.0018 18.0 8.2 4 7.8 0.3 6.7 6 2 0 6 6 6 1 Leucine Rich Repeat F-box-like PF12937.2 KFP08569.1 - 0.014 15.1 0.2 0.014 15.1 0.1 2.3 2 0 0 2 2 2 0 F-box-like LRR_7 PF13504.1 KFP08569.1 - 0.37 11.1 13.9 16 6.2 0.0 7.2 5 1 1 6 6 6 0 Leucine rich repeat Sec7 PF01369.15 KFP08570.1 - 9e-50 168.9 0.0 1.8e-49 167.9 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KFP08570.1 - 3.2e-37 127.3 0.0 9e-37 125.8 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KFP08570.1 - 2.4e-10 40.5 0.2 6.8e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 PH domain RHD PF00554.17 KFP08571.1 - 1.9e-66 222.9 0.1 3e-66 222.3 0.1 1.3 1 0 0 1 1 1 1 Rel homology domain (RHD) Ank PF00023.25 KFP08571.1 - 3.1e-42 140.3 14.1 5.1e-07 29.1 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 KFP08571.1 - 3.1e-39 133.1 8.5 8.5e-21 74.0 0.6 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFP08571.1 - 4e-31 103.9 6.5 5.3e-05 23.0 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KFP08571.1 - 4.2e-28 97.1 4.6 3.6e-09 36.8 0.1 5.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFP08571.1 - 4.6e-28 96.6 6.2 5.5e-08 32.8 0.2 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Death PF00531.17 KFP08571.1 - 6.1e-09 35.5 0.3 2.2e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Death domain Tim44 PF04280.10 KFP08571.1 - 0.0024 17.8 0.4 0.0061 16.5 0.1 1.7 2 0 0 2 2 2 1 Tim44-like domain Frag1 PF10277.4 KFP08572.1 - 1.1e-57 194.9 11.4 1.3e-57 194.7 7.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Serinc PF03348.10 KFP08572.1 - 0.023 13.4 3.5 0.017 13.8 1.2 1.5 1 1 1 2 2 2 0 Serine incorporator (Serinc) DUF2768 PF10966.3 KFP08572.1 - 0.023 14.8 1.1 0.023 14.8 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2768) Homeobox PF00046.24 KFP08574.1 - 1e-22 79.4 9.2 1.6e-22 78.8 6.4 1.3 1 0 0 1 1 1 1 Homeobox domain OAR PF03826.12 KFP08574.1 - 2e-09 36.6 1.4 5e-09 35.3 0.9 1.7 1 0 0 1 1 1 1 OAR domain Homeobox_KN PF05920.6 KFP08574.1 - 0.011 15.3 4.2 0.012 15.3 0.5 2.4 2 0 0 2 2 2 0 Homeobox KN domain ELO PF01151.13 KFP08575.1 - 1.3e-56 191.6 21.5 1.5e-56 191.4 14.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UDPGT PF00201.13 KFP08576.1 - 2e-107 359.7 0.0 2.3e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFP08576.1 - 0.0021 17.7 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFP08576.1 - 0.016 14.4 0.0 0.042 13.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 1 SNAPc_SNAP43 PF09808.4 KFP08576.1 - 0.16 11.6 0.1 0.32 10.6 0.0 1.5 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 SRP40_C PF05022.7 KFP08577.1 - 1.9e-27 95.5 3.5 5.2e-27 94.1 2.4 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain DBB PF14545.1 KFP08578.1 - 1.3e-44 151.1 0.0 2.1e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, EMP70 PF02990.11 KFP08579.1 - 1e-166 555.4 20.1 1.2e-166 555.1 13.9 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_8 PF00895.15 KFP08579.1 - 0.33 11.2 9.1 3 8.1 0.0 3.7 3 0 0 3 3 3 0 ATP synthase protein 8 GP41 PF00517.12 KFP08579.1 - 0.53 9.8 5.1 4.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Retroviral envelope protein EVC2_like PF12297.3 KFP08579.1 - 0.68 8.5 2.3 5 5.6 1.3 2.0 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein CUB PF00431.15 KFP08580.1 - 1.4e-185 604.5 6.3 4.3e-39 132.9 0.1 5.2 5 0 0 5 5 5 5 CUB domain Astacin PF01400.19 KFP08580.1 - 2.2e-73 245.7 0.0 4.1e-73 244.8 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FXa_inhibition PF14670.1 KFP08580.1 - 3.1e-14 52.7 28.5 2e-08 34.2 7.5 4.1 4 0 0 4 4 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KFP08580.1 - 9.8e-12 44.6 27.8 8.6e-07 28.8 5.9 2.8 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.2 KFP08580.1 - 2.6e-09 36.5 6.2 1.8e-05 24.2 1.1 3.2 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.2 KFP08580.1 - 5.7e-08 32.5 17.0 0.00073 19.4 2.2 3.0 2 0 0 2 2 2 2 EGF domain EGF PF00008.22 KFP08580.1 - 3.3e-06 26.9 23.3 0.0012 18.7 5.1 3.0 2 0 0 2 2 2 2 EGF-like domain CUB_2 PF02408.15 KFP08580.1 - 5.6e-06 25.8 0.7 0.82 9.2 0.0 5.1 5 0 0 5 5 5 2 CUB-like domain Reprolysin_4 PF13583.1 KFP08580.1 - 0.0011 18.5 0.2 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFP08580.1 - 0.013 15.2 2.0 0.71 9.5 0.1 2.8 3 0 0 3 3 3 0 Matrixin Reprolysin_2 PF13574.1 KFP08580.1 - 0.017 15.1 0.3 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like p450 PF00067.17 KFP08581.1 - 3.5e-141 470.8 0.0 3.9e-141 470.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Njmu-R1 PF15053.1 KFP08581.1 - 0.0023 16.7 0.0 0.0039 15.9 0.0 1.3 1 0 0 1 1 1 1 Mjmu-R1-like protein family DUF4657 PF15552.1 KFP08582.1 - 1.3e-05 24.6 1.0 2.8e-05 23.5 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4657) HAP1_N PF04849.8 KFP08582.1 - 0.049 12.5 0.5 0.078 11.9 0.3 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region SNF2_N PF00176.18 KFP08583.1 - 2.1e-58 197.4 0.0 2.1e-58 197.4 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFP08583.1 - 2.5e-18 65.7 0.0 7.6e-18 64.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFP08583.1 - 5.7e-11 41.7 0.2 1.3e-10 40.5 0.2 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFP08583.1 - 2.9e-06 27.2 0.1 0.00011 22.1 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFP08583.1 - 0.001 18.5 0.0 0.0031 17.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Shugoshin_C PF07557.6 KFP08583.1 - 0.04 13.3 0.8 0.075 12.5 0.6 1.5 1 0 0 1 1 1 0 Shugoshin C terminus PDZ PF00595.19 KFP08584.1 - 1.5e-12 47.4 0.1 4.2e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) LIM PF00412.17 KFP08584.1 - 3.8e-11 42.8 5.8 6.9e-11 42.0 4.0 1.4 1 0 0 1 1 1 1 LIM domain PDZ_2 PF13180.1 KFP08584.1 - 6.1e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Lar_restr_allev PF14354.1 KFP08584.1 - 0.33 11.2 2.2 0.72 10.1 1.5 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar SH3_9 PF14604.1 KFP08585.1 - 2.7e-42 142.1 0.8 7.5e-15 54.2 0.1 3.9 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KFP08585.1 - 5.4e-39 131.3 0.5 8.5e-12 44.2 0.0 4.2 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.12 KFP08585.1 - 2.6e-31 106.8 0.2 9.5e-13 47.4 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain Sorb PF02208.11 KFP08585.1 - 8.2e-23 79.5 0.6 2.4e-22 78.0 0.4 1.8 1 0 0 1 1 1 1 Sorbin homologous domain MitMem_reg PF13012.1 KFP08586.1 - 2e-21 76.1 0.1 3.5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KFP08586.1 - 3.5e-14 52.5 0.7 5.8e-14 51.8 0.5 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Annexin PF00191.15 KFP08587.1 - 3.2e-101 331.2 7.9 8.3e-28 96.0 0.4 4.1 4 0 0 4 4 4 4 Annexin Metallophos PF00149.23 KFP08588.1 - 2.1e-40 138.2 0.4 3.3e-40 137.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UCH PF00443.24 KFP08590.1 - 1.2e-19 70.4 0.3 1.2e-19 70.4 0.2 1.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-4CXXC_R1 PF10497.4 KFP08590.1 - 0.015 15.4 2.5 0.27 11.3 1.8 2.7 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 MIT PF04212.13 KFP08590.1 - 0.079 12.8 0.7 0.16 11.8 0.5 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Calsarcin PF05556.6 KFP08591.1 - 1.7e-85 286.5 0.0 2e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) PDZ PF00595.19 KFP08592.1 - 2.2e-11 43.7 0.0 4.8e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Calsarcin PF05556.6 KFP08592.1 - 8.8e-07 28.4 12.6 0.021 14.0 0.0 4.5 3 1 2 5 5 5 3 Calcineurin-binding protein (Calsarcin) PDZ_2 PF13180.1 KFP08592.1 - 0.19 11.6 0.0 0.51 10.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Sec23_trunk PF04811.10 KFP08593.1 - 1.2e-90 303.1 0.1 1.7e-90 302.6 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFP08593.1 - 1.3e-25 88.7 0.0 2.5e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFP08593.1 - 2.8e-19 69.4 0.0 2.6e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFP08593.1 - 2.3e-15 55.8 10.7 5e-15 54.7 7.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFP08593.1 - 6.5e-11 41.7 0.0 1.5e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat CHCH PF06747.8 KFP08594.1 - 4.3e-09 36.0 3.1 5.2e-09 35.7 2.1 1.1 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 KFP08594.1 - 0.0047 17.0 1.2 0.0068 16.5 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Cmc1 PF08583.5 KFP08594.1 - 0.33 10.7 3.7 2.8 7.7 1.7 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like SWIM PF04434.12 KFP08595.1 - 0.0012 18.3 5.7 0.0023 17.3 4.0 1.5 1 0 0 1 1 1 1 SWIM zinc finger HSNSD PF12062.3 KFP08597.1 - 3.6e-259 860.0 0.0 5.1e-259 859.5 0.0 1.2 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.22 KFP08597.1 - 3.7e-45 154.2 0.0 5.9e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 KFP08597.1 - 0.016 16.1 1.3 0.071 14.0 0.2 2.6 2 1 0 2 2 2 0 Sulfotransferase family Pkinase PF00069.20 KFP08598.1 - 1.2e-71 240.9 0.0 1.7e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CaMKII_AD PF08332.5 KFP08598.1 - 1.6e-60 202.6 0.0 2.7e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association Pkinase_Tyr PF07714.12 KFP08598.1 - 6.3e-32 110.6 0.0 1.2e-31 109.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4440 PF14534.1 KFP08598.1 - 1.2e-11 44.7 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 KFP08598.1 - 1.8e-11 44.1 0.0 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain APH PF01636.18 KFP08598.1 - 0.011 15.4 0.1 2.2 7.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family SnoaL_2 PF12680.2 KFP08598.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Kdo PF06293.9 KFP08598.1 - 0.042 12.9 0.1 0.077 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Yae1_N PF09811.4 KFP08599.1 - 7.1e-28 95.8 107.7 0.013 14.9 9.1 9.4 1 1 4 5 5 5 4 Essential protein Yae1, N terminal Trypsin PF00089.21 KFP08600.1 - 6.2e-67 225.3 0.8 8.2e-67 225.0 0.6 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.13 KFP08600.1 - 1.4e-16 60.2 4.3 3.1e-16 59.2 3.0 1.6 1 0 0 1 1 1 1 Kringle domain DUF1986 PF09342.6 KFP08600.1 - 0.0003 20.1 0.1 0.00064 19.0 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.1 KFP08600.1 - 0.00088 19.2 0.0 0.002 18.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.2 KFP08600.1 - 0.004 17.1 3.3 0.004 17.1 2.3 3.4 3 0 0 3 3 3 1 Human growth factor-like EGF EGF PF00008.22 KFP08600.1 - 0.0051 16.7 4.1 0.0051 16.7 2.9 3.1 4 1 0 4 4 4 1 EGF-like domain EGF_2 PF07974.8 KFP08600.1 - 0.015 15.4 8.2 0.015 15.4 5.7 2.8 2 0 0 2 2 2 0 EGF-like domain Tme5_EGF_like PF09064.5 KFP08600.1 - 0.47 10.1 6.0 0.8 9.3 1.2 3.2 2 1 1 3 3 3 0 Thrombomodulin like fifth domain, EGF-like PfkB PF00294.19 KFP08601.1 - 9.4e-78 261.3 0.2 1.1e-77 261.1 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFP08601.1 - 0.036 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DSPc PF00782.15 KFP08602.1 - 1.5e-31 108.7 0.0 1.1e-29 102.6 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFP08602.1 - 0.00041 19.7 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KFP08602.1 - 0.0029 16.5 0.0 0.0034 16.2 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DSPn PF14671.1 KFP08602.1 - 0.0059 16.5 0.0 0.037 14.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.1 KFP08602.1 - 0.042 13.8 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KFP08602.1 - 0.089 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PAP2_C PF14360.1 KFP08603.1 - 3.6e-28 97.6 10.0 3.6e-28 97.6 6.9 2.9 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.25 KFP08603.1 - 1.3e-11 44.4 0.1 3.2e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFP08603.1 - 3.4e-06 26.8 0.0 7.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFP08603.1 - 0.022 14.5 0.2 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain PAP2 PF01569.16 KFP08603.1 - 0.081 12.6 13.8 0.27 10.9 9.5 2.1 1 1 0 1 1 1 0 PAP2 superfamily PAP2_3 PF14378.1 KFP08603.1 - 1.6 8.2 12.9 2 7.9 8.0 2.0 1 1 1 2 2 2 0 PAP2 superfamily Porin_3 PF01459.17 KFP08604.1 - 2.8e-78 262.9 4.9 3.2e-78 262.7 3.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Methyltransf_3 PF01596.12 KFP08605.1 - 2.9e-79 264.8 0.1 3.4e-79 264.6 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KFP08605.1 - 6.6e-16 59.0 0.0 1.2e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP08605.1 - 1.6e-07 31.8 0.0 2.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP08605.1 - 2.4e-06 27.2 0.1 3.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFP08605.1 - 0.00028 20.4 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KFP08605.1 - 0.0015 17.6 0.1 0.0026 16.8 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFP08605.1 - 0.007 16.3 0.0 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain AFOR_N PF02730.10 KFP08605.1 - 0.016 14.5 0.1 0.061 12.6 0.0 1.9 1 1 1 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain UPF0146 PF03686.8 KFP08605.1 - 0.048 13.4 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) CMAS PF02353.15 KFP08605.1 - 0.068 12.2 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase BK_channel_a PF03493.13 KFP08606.1 - 1.5e-29 101.8 0.0 4.4e-29 100.3 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.26 KFP08606.1 - 1.9e-16 59.9 16.1 1.9e-16 59.9 11.2 2.3 3 0 0 3 3 3 1 Ion transport protein Ion_trans_2 PF07885.11 KFP08606.1 - 3.6e-14 52.2 2.9 3.6e-14 52.2 2.0 2.5 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.13 KFP08606.1 - 5.1e-06 26.4 0.1 6.8e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain RNA_pol_Rpb1_5 PF04998.12 KFP08607.1 - 6.8e-103 343.7 0.1 1.1e-102 343.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KFP08607.1 - 2.2e-102 342.8 0.8 3.4e-102 342.1 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KFP08607.1 - 3.9e-69 231.8 0.1 7.7e-69 230.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KFP08607.1 - 5.5e-42 143.1 0.0 9.8e-41 139.1 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KFP08607.1 - 1.9e-32 111.2 0.0 6.7e-32 109.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_S24e PF01282.14 KFP08608.1 - 5.3e-38 128.6 0.3 8.1e-38 128.1 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S24e DUF4519 PF15012.1 KFP08608.1 - 0.3 11.0 6.9 0.76 9.7 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ion_trans_2 PF07885.11 KFP08609.1 - 9.6e-12 44.4 1.1 4.6e-11 42.2 0.5 2.0 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.24 KFP08609.1 - 1.8e-11 43.7 0.0 4.5e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.26 KFP08609.1 - 0.00038 19.7 0.1 0.00074 18.8 0.1 1.4 1 0 0 1 1 1 1 Ion transport protein DUF4477 PF14780.1 KFP08609.1 - 0.018 14.4 0.9 3.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) DUF1664 PF07889.7 KFP08609.1 - 0.074 12.8 1.5 0.17 11.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.7 KFP08609.1 - 0.09 13.1 1.9 0.27 11.6 1.3 1.8 1 0 0 1 1 1 0 SlyX LPP PF04728.8 KFP08609.1 - 0.74 9.6 3.0 0.53 10.1 0.7 1.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.17 KFP08609.1 - 1.8 8.6 5.4 0.27 11.2 0.6 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 KFP08609.1 - 2.1 8.6 6.0 0.31 11.3 1.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 KFP08609.1 - 3.3 7.5 8.7 1.7 8.4 2.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding EF-hand_7 PF13499.1 KFP08610.1 - 1.2e-11 44.5 6.0 2.5e-11 43.5 4.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFP08610.1 - 8.1e-11 40.4 2.8 2.3e-05 23.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KFP08610.1 - 1.7e-08 33.4 2.3 0.00023 20.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFP08610.1 - 2.1e-08 33.3 4.4 8e-05 22.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFP08610.1 - 1.3e-06 27.9 2.6 2.8e-06 26.8 1.8 1.6 1 0 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFP08610.1 - 0.018 15.0 1.2 0.037 14.0 0.9 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KFP08610.1 - 0.033 13.8 1.2 0.097 12.3 0.6 1.9 1 1 1 2 2 2 0 EF hand Ras PF00071.17 KFP08611.1 - 2.6e-63 212.2 0.3 3e-63 212.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP08611.1 - 4.3e-21 75.6 0.0 7.7e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP08611.1 - 7.9e-13 48.0 0.0 9.7e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFP08611.1 - 2.9e-06 26.6 0.1 3.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFP08611.1 - 8.6e-05 22.0 0.1 0.0002 20.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP08611.1 - 0.00015 21.7 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFP08611.1 - 0.063 12.4 0.1 0.17 11.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PP2C PF00481.16 KFP08612.1 - 1.6e-29 103.1 0.1 1.1e-24 87.1 0.0 3.7 3 1 1 4 4 4 2 Protein phosphatase 2C PCAF_N PF06466.6 KFP08613.1 - 2.2e-132 440.0 0.4 3.2e-132 439.4 0.3 1.3 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.20 KFP08613.1 - 8.7e-27 92.8 0.3 2e-26 91.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KFP08613.1 - 3.8e-11 42.9 0.3 8.8e-11 41.8 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFP08613.1 - 6.5e-09 35.7 0.1 1.7e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-met PF12874.2 KFP08614.1 - 2.8e-22 78.1 16.9 1.1e-08 34.9 1.8 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP08614.1 - 2.7e-18 65.5 15.3 1.4e-07 31.4 1.9 3.3 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFP08614.1 - 9.3e-08 32.1 6.8 0.013 15.6 0.1 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 KFP08614.1 - 1.1e-06 28.1 6.6 0.049 13.1 0.0 3.3 3 0 0 3 3 3 3 U1 zinc finger AKAP95 PF04988.7 KFP08614.1 - 3.2e-06 27.0 8.8 0.11 12.2 0.6 3.2 3 0 0 3 3 3 3 A-kinase anchoring protein 95 (AKAP95) DUF3449 PF11931.3 KFP08614.1 - 0.0058 16.1 1.7 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) zf-C2H2 PF00096.21 KFP08614.1 - 0.01 16.1 11.0 1.1 9.7 1.4 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08614.1 - 0.017 15.4 11.2 1.7 9.1 1.0 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-DBF PF07535.7 KFP08614.1 - 0.023 14.3 7.2 0.086 12.5 0.8 3.2 3 0 0 3 3 3 0 DBF zinc finger OrfB_Zn_ribbon PF07282.6 KFP08614.1 - 0.036 13.7 4.7 3 7.5 0.3 3.4 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 KFP08614.1 - 0.48 10.2 5.3 9.8 6.0 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbons Yae1_N PF09811.4 KFP08615.1 - 1.8e-19 68.9 47.4 1.5e+04 -11.5 32.8 5.4 1 1 0 1 1 1 0 Essential protein Yae1, N terminal zf-met PF12874.2 KFP08616.1 - 1.5e-08 34.5 0.6 3.8e-08 33.2 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFP08616.1 - 3.5e-06 26.9 0.4 3.5e-06 26.9 0.3 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Annexin PF00191.15 KFP08616.1 - 0.15 12.0 0.3 0.2 11.5 0.2 1.2 1 0 0 1 1 1 0 Annexin UQ_con PF00179.21 KFP08617.1 - 4.6e-43 146.0 0.0 5e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP08617.1 - 2.9e-05 23.8 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFP08617.1 - 0.0028 17.5 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFP08617.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.21 KFP08618.1 - 6.1e-43 145.6 0.0 6.7e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFP08618.1 - 6.4e-05 22.7 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFP08618.1 - 0.0036 17.1 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFP08618.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain Ras PF00071.17 KFP08619.1 - 3.6e-26 91.4 0.3 4.2e-26 91.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP08619.1 - 2e-17 63.8 0.1 2.9e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP08619.1 - 8.1e-09 34.9 0.3 1.1e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFP08619.1 - 0.00037 20.4 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFP08619.1 - 0.0012 18.3 1.3 0.12 11.8 0.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KFP08619.1 - 0.0018 18.2 0.1 0.0051 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 KFP08619.1 - 0.015 15.1 0.4 0.22 11.3 0.3 2.7 1 1 0 1 1 1 0 Dynamin family cobW PF02492.14 KFP08619.1 - 0.038 13.4 2.2 1.2 8.5 0.2 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 KFP08619.1 - 0.075 12.3 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.24 KFP08619.1 - 0.14 12.3 0.3 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFP08619.1 - 0.22 11.6 0.8 0.94 9.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain Ribosomal_L15e PF00827.12 KFP08620.1 - 3.1e-98 326.9 5.7 3.6e-98 326.7 4.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 Hormone_recep PF00104.25 KFP08621.1 - 7e-33 113.4 0.1 7e-33 113.4 0.0 2.0 3 0 0 3 3 3 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.13 KFP08621.1 - 2.7e-31 107.6 15.9 6.6e-31 106.3 11.0 1.7 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-C4 PF00105.13 KFP08622.1 - 1.7e-30 105.0 15.9 3.2e-30 104.1 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFP08622.1 - 8.2e-21 74.0 0.0 1.2e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Class_IIIsignal PF04021.7 KFP08623.1 - 0.37 10.5 0.1 0.37 10.5 0.1 2.1 2 0 0 2 2 2 0 Class III signal peptide zf-C4 PF00105.13 KFP08624.1 - 3.4e-34 116.8 16.3 4e-34 116.6 11.3 1.0 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFP08625.1 - 8.5e-21 74.0 0.0 1.4e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Transglut_core PF01841.14 KFP08626.1 - 1.4e-14 54.2 1.5 2.2e-14 53.5 0.4 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily PUB PF09409.5 KFP08626.1 - 1.8e-14 53.2 0.4 9.2e-14 50.9 0.0 2.4 2 0 0 2 2 2 1 PUB domain Rad4 PF03835.10 KFP08626.1 - 1.3e-10 40.8 1.1 2.6e-10 39.8 0.7 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain DUF750 PF04721.12 KFP08626.1 - 2.2e-07 30.7 0.6 5.5e-07 29.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF750) ketoacyl-synt PF00109.21 KFP08627.1 - 4.3e-53 180.3 2.6 4.3e-53 180.3 1.8 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFP08627.1 - 4.5e-36 123.3 0.7 7.8e-36 122.5 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KFP08627.1 - 1.9e-05 23.7 0.0 5.5e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain LRR_8 PF13855.1 KFP08628.1 - 3.6e-18 65.0 2.7 5.9e-11 41.9 0.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KFP08628.1 - 3.2e-11 42.5 7.8 5.6e-07 29.0 0.3 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFP08628.1 - 4.7e-11 41.1 8.5 0.0015 18.2 0.5 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRRNT PF01462.13 KFP08628.1 - 6.6e-09 35.0 2.8 6.6e-09 35.0 2.0 2.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_5 PF13306.1 KFP08628.1 - 1.3e-06 28.1 0.1 2.1e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_7 PF13504.1 KFP08628.1 - 5.4e-06 25.7 4.8 0.55 10.6 0.1 5.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KFP08628.1 - 7.7e-06 25.4 2.2 0.17 12.0 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich repeat Pkinase PF00069.20 KFP08630.1 - 3.7e-31 108.2 1.0 1e-30 106.7 0.7 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08630.1 - 3.2e-21 75.5 0.1 5.3e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.18 KFP08630.1 - 7.4e-06 25.6 6.6 0.0014 18.3 0.1 4.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat APH PF01636.18 KFP08630.1 - 0.00019 21.2 0.1 0.003 17.3 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family HEAT_2 PF13646.1 KFP08630.1 - 0.00064 19.9 1.1 0.17 12.1 0.1 2.7 2 0 0 2 2 2 2 HEAT repeats RIO1 PF01163.17 KFP08630.1 - 0.0011 18.4 0.2 0.002 17.4 0.2 1.6 1 0 0 1 1 1 1 RIO1 family HCO3_cotransp PF00955.16 KFP08631.1 - 3.4e-246 817.8 9.2 4.2e-246 817.5 6.4 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 KFP08631.1 - 8.9e-106 353.1 0.0 1.5e-105 352.4 0.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain T-box PF00907.17 KFP08632.1 - 3.1e-66 222.3 0.3 4.1e-66 221.9 0.2 1.2 1 0 0 1 1 1 1 T-box Yae1_N PF09811.4 KFP08633.1 - 2.5e-14 52.4 34.5 90 2.7 23.9 4.2 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Cmc1 PF08583.5 KFP08634.1 - 4.8e-18 64.6 4.6 6.2e-18 64.3 3.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Colipase PF01114.13 KFP08634.1 - 0.0094 15.4 0.8 0.015 14.8 0.5 1.3 1 0 0 1 1 1 1 Colipase, N-terminal domain Tmemb_18A PF09771.4 KFP08634.1 - 0.039 13.9 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 188 COX17 PF05051.8 KFP08634.1 - 0.095 12.7 0.5 0.095 12.7 0.3 2.3 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NDUF_B7 PF05676.8 KFP08634.1 - 0.9 8.9 6.5 0.18 11.2 1.4 1.9 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 KFP08634.1 - 1.4 8.9 10.2 3.9 7.5 3.4 2.5 2 1 1 3 3 3 0 CHCH domain TBD PF12845.2 KFP08635.1 - 1.1e-17 63.2 2.1 9.4e-17 60.3 0.4 2.9 2 0 0 2 2 2 1 TBD domain Rota_NSP4 PF01452.11 KFP08635.1 - 0.01 15.1 4.6 0.021 14.1 3.2 1.4 1 0 0 1 1 1 0 Rotavirus non structural protein Speriolin_N PF15058.1 KFP08635.1 - 0.31 10.9 3.9 0.85 9.4 2.7 1.8 1 1 0 1 1 1 0 Speriolin N terminus DivIC PF04977.10 KFP08635.1 - 1.1 8.8 0.0 1.1 8.8 0.0 4.5 4 1 0 4 4 4 0 Septum formation initiator Fib_alpha PF08702.5 KFP08635.1 - 2.6 8.1 25.9 0.74 9.9 8.6 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KFP08635.1 - 2.9 7.4 35.1 1.9 8.0 7.6 2.1 1 1 1 2 2 2 0 IncA protein P4Ha_N PF08336.6 KFP08635.1 - 5.4 6.8 14.4 0.22 11.3 1.0 2.7 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RRM_1 PF00076.17 KFP08636.1 - 3.8e-32 109.7 0.0 1.5e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFP08636.1 - 1.6e-26 92.0 0.0 1.1e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFP08636.1 - 3.5e-13 49.1 0.0 5.8e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KFP08637.1 - 1.9e-49 168.1 0.2 3.7e-49 167.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain ecTbetaR2 PF08917.5 KFP08637.1 - 2.3e-49 166.0 17.4 7e-49 164.5 12.1 1.9 1 0 0 1 1 1 1 Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr PF07714.12 KFP08637.1 - 1.4e-35 122.6 0.0 2.5e-35 121.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.1 KFP08637.1 - 0.014 15.0 0.2 0.037 13.7 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.1 KFP08637.1 - 0.042 13.3 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) APH PF01636.18 KFP08637.1 - 0.051 13.2 0.1 0.082 12.6 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family 7tm_1 PF00001.16 KFP08637.1 - 0.058 12.5 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Pyridoxal_deC PF00282.14 KFP08638.1 - 2.6e-113 378.2 0.0 3.1e-113 378.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFP08638.1 - 1.5e-05 23.8 0.0 5e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFP08638.1 - 3.7e-05 23.0 0.0 4.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 KFP08638.1 - 0.086 11.2 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) STT3 PF02516.9 KFP08639.1 - 5.1e-120 401.6 37.1 3.5e-119 398.9 25.7 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Oxysterol_BP PF01237.13 KFP08640.1 - 4e-72 242.6 0.1 1.3e-71 240.9 0.1 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KFP08640.1 - 2.3e-08 33.9 0.0 4.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFP08640.1 - 0.00016 21.8 0.0 0.0004 20.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 KFP08640.1 - 0.0082 16.1 0.0 0.03 14.3 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain NAD_Gly3P_dh_C PF07479.9 KFP08641.1 - 2.5e-57 192.7 0.2 3.9e-57 192.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KFP08641.1 - 1.3e-46 158.2 0.3 2.5e-46 157.2 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KFP08641.1 - 0.045 14.1 0.1 0.17 12.3 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.10 KFP08641.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain MARVEL PF01284.18 KFP08642.1 - 1.2e-18 67.3 18.3 1.5e-18 67.0 12.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain MARVEL PF01284.18 KFP08643.1 - 3.6e-13 49.5 17.0 6.6e-13 48.7 11.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain Herpes_LMP1 PF05297.6 KFP08643.1 - 0.39 9.6 4.5 0.46 9.3 3.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) NfeD PF01957.13 KFP08643.1 - 0.42 10.7 9.4 0.32 11.1 3.1 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding TMEM192 PF14802.1 KFP08643.1 - 2 7.1 5.4 0.33 9.7 0.8 1.8 2 0 0 2 2 2 0 TMEM192 family DLIC PF05783.6 KFP08645.1 - 3.5e-228 757.9 0.0 4.1e-228 757.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Miro PF08477.8 KFP08645.1 - 0.0021 18.5 0.5 0.082 13.4 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 KFP08645.1 - 0.056 12.8 0.5 0.32 10.4 0.0 2.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Ras PF00071.17 KFP08645.1 - 0.17 11.2 0.2 2.3 7.6 0.0 2.4 2 1 0 2 2 2 0 Ras family TPR_1 PF00515.23 KFP08646.1 - 8.1e-15 53.7 15.4 1.8e-05 24.1 0.1 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFP08646.1 - 1.8e-14 53.0 20.3 0.00034 20.1 0.1 7.1 7 0 0 7 7 7 5 TPR repeat TPR_2 PF07719.12 KFP08646.1 - 1.7e-13 49.3 25.0 0.00078 19.1 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFP08646.1 - 5.8e-12 45.3 17.3 0.00092 19.1 0.0 6.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFP08646.1 - 1.3e-08 35.2 0.6 5.8 7.7 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFP08646.1 - 2.3e-07 31.0 16.3 1.4 9.2 0.5 8.6 7 3 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFP08646.1 - 4.4e-07 29.5 6.1 1.6 9.1 0.0 7.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFP08646.1 - 1.2e-06 28.6 4.0 18 6.3 0.0 8.3 8 1 1 9 9 9 0 Tetratricopeptide repeat Apc3 PF12895.2 KFP08646.1 - 5.7e-06 26.3 20.6 2.6 8.2 0.4 7.4 5 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFP08646.1 - 2.8e-05 23.5 3.0 0.013 15.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFP08646.1 - 4.3e-05 22.9 12.8 0.13 12.1 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFP08646.1 - 0.00016 21.4 0.5 1 9.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat BLOC1_2 PF10046.4 KFP08646.1 - 0.0075 16.3 1.9 0.035 14.2 1.3 2.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_6 PF13174.1 KFP08646.1 - 0.029 14.8 4.4 21 5.8 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat NHL PF01436.16 KFP08647.1 - 1.9e-54 178.9 15.0 1.6e-10 40.4 0.0 6.6 6 0 0 6 6 6 6 NHL repeat Filamin PF00630.14 KFP08647.1 - 8e-18 64.8 0.0 4.4e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Filamin/ABP280 repeat SGL PF08450.7 KFP08647.1 - 2.5e-11 43.4 0.4 0.0058 16.0 0.0 6.1 3 1 4 7 7 7 3 SMP-30/Gluconolaconase/LRE-like region zf-B_box PF00643.19 KFP08647.1 - 3.2e-06 26.9 2.8 3.2e-06 26.9 2.0 2.0 2 0 0 2 2 2 1 B-box zinc finger potato_inhibit PF00280.13 KFP08647.1 - 0.27 11.4 5.1 38 4.5 0.1 4.6 5 0 0 5 5 5 0 Potato inhibitor I family DUF4461 PF14688.1 KFP08648.1 - 4.6e-110 367.8 1.6 6.9e-110 367.2 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.1 KFP08648.1 - 4.1e-33 113.5 0.1 1.1e-32 112.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF3962 PF13111.1 KFP08648.1 - 0.083 12.2 0.4 0.42 9.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3962) Asp_Glu_race_2 PF14669.1 KFP08649.1 - 4.3e-74 248.7 0.0 1.7e-66 223.8 0.1 2.4 2 0 0 2 2 2 2 Putative aspartate racemase PPR PF01535.15 KFP08649.1 - 0.0091 15.9 1.6 23 5.2 0.0 5.7 7 0 0 7 7 7 1 PPR repeat Abhydrolase_6 PF12697.2 KFP08650.1 - 1.2e-30 107.1 0.0 1.4e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFP08650.1 - 9.3e-19 67.8 0.0 6.6e-18 65.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFP08650.1 - 3.9e-11 42.8 0.0 8.1e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFP08650.1 - 0.00019 21.2 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KFP08650.1 - 0.00053 18.5 0.0 0.0017 16.9 0.0 1.7 2 0 0 2 2 2 1 Ndr family Abhydrolase_3 PF07859.8 KFP08650.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 KFP08650.1 - 0.06 11.6 0.0 0.11 10.7 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF1071 PF06378.6 KFP08650.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Anoctamin PF04547.7 KFP08651.1 - 3.2e-146 487.5 23.0 3.8e-146 487.2 15.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ATE_C PF04377.10 KFP08651.1 - 0.047 13.7 0.5 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Pkinase PF00069.20 KFP08652.1 - 2.1e-73 246.6 0.0 5e-73 245.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08652.1 - 4.5e-42 143.9 0.0 6.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFP08652.1 - 3.8e-10 39.2 0.0 2.3e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFP08652.1 - 0.017 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFP08652.1 - 0.073 12.3 0.0 0.78 9.0 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF563 PF04577.9 KFP08653.1 - 2.8e-22 79.6 0.1 6.1e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FAM198 PF15051.1 KFP08654.1 - 6.6e-136 452.2 0.0 7.3e-136 452.1 0.0 1.0 1 0 0 1 1 1 1 FAM198 protein Ribosomal_L14e PF01929.12 KFP08655.1 - 2.1e-31 108.0 7.7 4.5e-31 107.0 5.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KFP08655.1 - 0.0091 15.6 0.1 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 KOW motif DRY_EERY PF09750.4 KFP08655.1 - 0.32 11.1 3.6 0.48 10.5 2.5 1.4 1 1 0 1 1 1 0 Alternative splicing regulator AIG2_2 PF13772.1 KFP08656.1 - 6.6e-30 103.0 0.1 9e-30 102.6 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 KFP08656.1 - 5.4e-06 26.8 0.0 8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family XG_FTase PF03254.8 KFP08656.1 - 0.0061 15.1 0.0 0.01 14.3 0.0 1.4 1 1 1 2 2 2 1 Xyloglucan fucosyltransferase NACHT PF05729.7 KFP08657.1 - 9.3e-33 113.2 0.0 2.3e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain LRR_6 PF13516.1 KFP08657.1 - 1.1e-20 71.3 1.7 0.099 12.7 0.0 8.9 8 0 0 8 8 8 6 Leucine Rich repeat CARD PF00619.16 KFP08657.1 - 1.6e-14 53.5 0.5 2.2e-13 49.8 0.1 2.9 3 0 0 3 3 3 1 Caspase recruitment domain LRR_4 PF12799.2 KFP08657.1 - 7.8e-09 34.9 2.4 0.45 10.2 0.0 5.3 4 1 1 6 6 6 3 Leucine Rich repeats (2 copies) AAA_16 PF13191.1 KFP08657.1 - 0.00032 20.7 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SpoU_sub_bind PF08032.7 KFP08657.1 - 0.018 15.2 2.6 3 8.0 0.1 4.0 2 1 2 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding AAA_22 PF13401.1 KFP08657.1 - 0.058 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain LRR_1 PF00560.28 KFP08657.1 - 0.17 12.0 3.4 26 5.3 0.4 5.4 5 2 0 5 5 5 0 Leucine Rich Repeat DUF4581 PF15167.1 KFP08658.1 - 7.2e-54 181.0 1.0 7.9e-54 180.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4581) Toxin_27 PF08099.6 KFP08658.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Scorpion calcine family EAF PF09816.4 KFP08659.1 - 2.9e-28 98.0 0.0 5.4e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor TFIIIC_delta PF12657.2 KFP08659.1 - 0.0067 16.1 1.0 0.02 14.5 0.7 1.9 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Macoilin PF09726.4 KFP08659.1 - 2.2 6.4 8.8 2.7 6.1 6.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_12 PF08242.7 KFP08660.1 - 5.3e-17 62.1 0.1 4.2e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFP08660.1 - 4.8e-15 55.6 0.1 7.6e-15 54.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFP08660.1 - 4.5e-12 45.8 0.1 6.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFP08660.1 - 6.3e-12 46.0 0.0 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFP08660.1 - 3.1e-10 40.4 0.1 1.2e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFP08660.1 - 9e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFP08660.1 - 9.8e-08 32.2 0.1 2.8e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KFP08660.1 - 7.8e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KFP08660.1 - 0.00027 20.1 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFP08660.1 - 0.00058 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 KFP08660.1 - 0.0043 16.0 0.0 0.0063 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) CheR PF01739.13 KFP08660.1 - 0.0091 15.3 0.4 2.3 7.4 0.0 2.5 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Thioredoxin PF00085.15 KFP08661.1 - 4.3e-99 325.1 1.2 4.9e-32 109.6 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 KFP08661.1 - 2.1e-26 92.8 10.3 2.4e-17 63.3 1.0 5.0 3 2 0 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFP08661.1 - 6.3e-22 77.5 4.3 3.1e-05 24.0 0.0 6.6 4 3 2 6 6 6 4 Thioredoxin-like Thioredoxin_2 PF13098.1 KFP08661.1 - 2.9e-21 75.7 7.2 4.3e-06 26.8 0.0 5.2 4 3 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFP08661.1 - 2.4e-15 56.3 0.0 0.00041 20.3 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin-like Calsequestrin PF01216.12 KFP08661.1 - 4e-13 48.9 7.7 2.4e-12 46.3 0.1 3.0 1 1 1 3 3 3 2 Calsequestrin AhpC-TSA PF00578.16 KFP08661.1 - 3.1e-10 39.8 1.0 0.026 14.2 0.0 4.1 3 1 1 4 4 4 3 AhpC/TSA family Redoxin PF08534.5 KFP08661.1 - 2.5e-08 33.5 0.7 0.19 11.3 0.0 4.0 4 0 0 4 4 4 3 Redoxin Thioredoxin_4 PF13462.1 KFP08661.1 - 3e-08 33.8 2.1 0.3 11.0 0.0 4.9 5 0 0 5 5 5 3 Thioredoxin HyaE PF07449.6 KFP08661.1 - 0.0003 20.6 0.0 3.8 7.4 0.0 3.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 KFP08661.1 - 0.00036 20.0 0.1 0.91 9.0 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin TraF PF13728.1 KFP08661.1 - 0.0031 17.0 0.0 0.7 9.3 0.0 3.2 3 0 0 3 3 3 1 F plasmid transfer operon protein Omp28 PF11551.3 KFP08661.1 - 0.012 15.2 0.0 3.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Outer membrane protein Omp28 DSBA PF01323.15 KFP08661.1 - 0.014 14.9 2.0 29 4.1 0.1 4.8 3 3 3 6 6 6 0 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.1 KFP08661.1 - 0.39 10.2 3.5 27 4.2 0.1 4.4 4 1 1 5 5 5 0 Thioredoxin Mu-like_Com PF10122.4 KFP08661.1 - 0.54 9.3 5.1 16 4.6 0.1 3.2 3 0 0 3 3 3 0 Mu-like prophage protein Com SET PF00856.23 KFP08662.1 - 1.3e-22 80.7 0.6 1.3e-22 80.7 0.4 2.9 2 2 0 2 2 2 1 SET domain EZH2_WD-Binding PF11616.3 KFP08662.1 - 5.9e-19 67.6 4.3 1.3e-18 66.4 3.0 1.6 1 0 0 1 1 1 1 WD repeat binding protein EZH2 Cullin PF00888.17 KFP08664.1 - 4.9e-173 576.8 22.2 6.4e-173 576.4 15.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFP08664.1 - 5.1e-28 96.6 2.7 5.1e-28 96.6 1.9 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain Laminin_G_2 PF02210.19 KFP08665.1 - 1.6e-50 170.4 0.1 6.5e-24 84.4 0.1 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.18 KFP08665.1 - 8e-31 106.7 0.0 1.2e-14 54.4 0.0 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.1 KFP08665.1 - 3.4e-06 27.3 0.1 0.00062 20.0 0.0 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Syndecan PF01034.15 KFP08665.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EGF_2 PF07974.8 KFP08665.1 - 0.68 10.1 10.1 1.5 9.0 7.0 1.6 1 1 0 1 1 1 0 EGF-like domain TAFA PF12020.3 KFP08666.1 - 5e-40 135.5 8.6 6.4e-40 135.1 5.9 1.1 1 0 0 1 1 1 1 TAFA family Lipase_GDSL_2 PF13472.1 KFP08667.1 - 1.1e-05 25.6 0.0 2.3e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family UCH PF00443.24 KFP08668.1 - 1.5e-93 312.8 0.0 3.1e-93 311.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.1 KFP08668.1 - 5.8e-38 128.4 0.1 1.2e-37 127.4 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain UCH_1 PF13423.1 KFP08668.1 - 8.2e-24 84.5 0.0 8.9e-14 51.6 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFP08668.1 - 3.6e-18 65.7 0.8 3.6e-18 65.7 0.6 2.9 2 1 0 2 2 2 1 DUSP domain USP7_C2 PF14533.1 KFP08668.1 - 1.4e-07 31.1 0.2 2.2e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal Sec7_N PF12783.2 KFP08669.1 - 2e-27 95.6 9.0 3.8e-13 49.2 0.4 4.2 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFP08669.1 - 2.4e-19 68.6 0.3 1.7e-17 62.6 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HEAT PF02985.17 KFP08669.1 - 0.0016 18.3 0.5 17 5.8 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat PP2C PF00481.16 KFP08670.1 - 6e-28 97.9 0.0 4.2e-12 45.9 0.0 3.0 3 0 0 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.7 KFP08670.1 - 2.1e-05 24.2 0.0 0.056 13.1 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KFP08670.1 - 0.00012 21.5 0.0 0.002 17.5 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C Exostosin PF03016.10 KFP08671.1 - 1.2e-05 24.5 0.0 2.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Exostosin family DUF2827 PF10933.3 KFP08671.1 - 0.0095 14.4 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2827) RhoGAP PF00620.22 KFP08672.1 - 2.3e-46 157.1 0.3 2.5e-45 153.8 0.0 2.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KFP08672.1 - 4.8e-19 68.3 6.1 2.5e-18 66.0 4.2 2.4 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFP08672.1 - 7.8e-11 41.3 0.0 1.3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFP08672.1 - 2.3e-10 39.7 0.0 4.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFP08672.1 - 4.6e-09 35.6 0.0 9.7e-09 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FlaC_arch PF05377.6 KFP08672.1 - 0.0097 15.7 0.8 0.062 13.1 0.6 2.4 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) DUF2003 PF09404.5 KFP08673.1 - 1.7e-280 929.8 7.4 1.9e-280 929.7 5.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF2003) Ribosomal_L18ae PF01775.12 KFP08674.1 - 1.1e-57 193.2 0.1 1.4e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain C1_1 PF00130.17 KFP08675.1 - 0.05 13.3 4.9 0.07 12.8 3.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vanabin-2 PF11437.3 KFP08675.1 - 0.11 12.4 1.0 0.12 12.3 0.7 1.1 1 0 0 1 1 1 0 Vanadium-binding protein 2 RA PF00788.18 KFP08676.1 - 1e-21 77.1 0.1 1.4e-20 73.5 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Pepsin-I3 PF06394.8 KFP08676.1 - 0.1 12.2 3.6 0.49 10.1 0.2 2.7 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain EF-hand_like PF09279.6 KFP08676.1 - 0.11 12.5 1.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RabGAP-TBC PF00566.13 KFP08677.1 - 1.3e-39 135.8 0.1 3.8e-39 134.3 0.1 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pex26 PF07163.7 KFP08677.1 - 0.083 11.7 0.4 0.15 10.9 0.3 1.3 1 0 0 1 1 1 0 Pex26 protein 60KD_IMP PF02096.15 KFP08677.1 - 0.32 10.6 4.3 0.15 11.6 0.5 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein WIF PF02019.13 KFP08679.1 - 4.5e-33 113.4 0.0 5.9e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 WIF domain EGF_2 PF07974.8 KFP08679.1 - 5e-19 68.1 90.5 0.0002 21.4 9.5 5.3 5 0 0 5 5 5 5 EGF-like domain hEGF PF12661.2 KFP08679.1 - 4.8e-17 60.7 43.8 0.00094 19.1 1.7 6.4 5 0 0 5 5 5 5 Human growth factor-like EGF EGF PF00008.22 KFP08679.1 - 8.8e-11 41.5 83.7 0.00018 21.4 5.2 5.7 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.19 KFP08679.1 - 2.2 8.2 70.6 3 7.8 6.5 5.3 1 1 4 5 5 5 0 Laminin EGF-like (Domains III and V) MSC PF09402.5 KFP08680.1 - 2.8e-50 170.9 0.5 4.4e-50 170.2 0.4 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RRM_5 PF13893.1 KFP08680.1 - 0.0027 17.5 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KFP08680.1 - 0.047 13.9 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein SelR PF01641.13 KFP08681.1 - 1.7e-51 173.0 0.1 2.2e-51 172.7 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KFP08681.1 - 0.018 14.8 0.4 0.16 11.8 0.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.9 KFP08681.1 - 0.034 14.1 0.2 0.12 12.4 0.1 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_2 PF13240.1 KFP08681.1 - 0.034 13.6 0.4 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 KFP08681.1 - 0.075 12.9 1.9 1.6 8.7 0.1 2.3 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.1 KFP08681.1 - 0.14 12.0 4.1 0.43 10.4 0.1 2.8 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HYPF PF07503.7 KFP08681.1 - 0.31 10.4 1.8 1.7 8.1 0.1 2.8 3 0 0 3 3 3 0 HypF finger zf-HIT PF04438.11 KFP08681.1 - 0.36 10.4 3.3 6 6.6 0.0 2.8 2 1 0 2 2 2 0 HIT zinc finger Auto_anti-p27 PF06677.7 KFP08681.1 - 0.43 10.3 4.5 1.3 8.8 0.1 2.7 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-tcix PF14952.1 KFP08681.1 - 7 6.0 6.6 14 5.1 0.1 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding AT_hook PF02178.14 KFP08682.1 - 0.0049 16.3 26.9 0.068 12.8 5.0 3.2 3 1 0 3 3 3 2 AT hook motif mono-CXXC PF15626.1 KFP08682.1 - 3.8 7.5 5.6 1.3 9.0 2.2 1.5 1 1 1 2 2 2 0 single CXXC unit Laps PF10169.4 KFP08684.1 - 2.2e-36 124.9 24.1 3.6e-36 124.2 16.7 1.3 1 1 0 1 1 1 1 Learning-associated protein DUF2423 PF10338.4 KFP08684.1 - 0.003 17.4 7.4 0.003 17.4 5.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Draxin PF15550.1 KFP08684.1 - 3 7.4 9.7 3.9 7.0 6.7 1.0 1 0 0 1 1 1 0 Draxin Nop53 PF07767.6 KFP08684.1 - 3.5 6.4 19.2 13 4.6 13.3 1.7 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Bax1-I PF01027.15 KFP08685.1 - 1.6e-47 161.7 27.2 1.8e-47 161.6 18.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.6 KFP08685.1 - 0.48 10.0 27.8 2 8.0 9.8 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling Transport_MerF PF11431.3 KFP08685.1 - 0.64 9.7 10.5 4.4 7.0 0.0 3.9 4 0 0 4 4 4 0 Membrane transport protein MerF DUF3325 PF11804.3 KFP08685.1 - 4.4 7.2 11.7 0.77 9.7 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) YoqO PF14037.1 KFP08685.1 - 5.1 7.2 12.3 0.84 9.7 4.4 2.5 2 1 1 3 3 3 0 YoqO-like protein AAA_30 PF13604.1 KFP08686.1 - 6.8e-25 87.8 0.0 6e-24 84.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KFP08686.1 - 1.3e-11 44.5 0.0 4.1e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KFP08686.1 - 7.2e-09 35.5 1.0 0.064 12.7 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KFP08686.1 - 2.5e-07 30.3 0.0 9.8e-07 28.4 0.0 2.1 1 1 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KFP08686.1 - 3e-05 23.7 0.8 0.14 11.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain DUF258 PF03193.11 KFP08686.1 - 0.00044 19.4 0.2 0.001 18.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KFP08686.1 - 0.00052 20.3 0.0 0.0021 18.3 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.1 KFP08686.1 - 0.0011 19.1 0.3 0.099 12.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain CbiA PF01656.18 KFP08686.1 - 0.0045 16.4 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 KFP08686.1 - 0.0067 16.4 0.0 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KFP08686.1 - 0.013 15.3 0.0 0.11 12.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.10 KFP08686.1 - 0.14 11.1 1.8 1.1 8.2 0.4 2.6 2 1 1 3 3 3 0 Anion-transporting ATPase AAA_18 PF13238.1 KFP08686.1 - 0.16 12.2 1.9 1.6 9.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain PDZ PF00595.19 KFP08687.1 - 5.7e-91 298.7 7.6 3.6e-14 52.6 0.0 7.2 7 0 0 7 7 7 7 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 KFP08687.1 - 1.5e-37 127.3 4.7 1.4e-06 28.0 0.0 7.4 7 0 0 7 7 7 7 PDZ domain Tricorn_PDZ PF14685.1 KFP08687.1 - 7e-14 51.3 1.2 0.063 13.0 0.0 6.4 6 0 0 6 6 6 4 Tricorn protease PDZ domain GRASP55_65 PF04495.9 KFP08687.1 - 0.00023 21.1 0.1 3.8 7.4 0.0 4.1 2 2 1 4 4 4 2 GRASP55/65 PDZ-like domain MoaE PF02391.12 KFP08687.1 - 0.0043 16.8 0.4 16 5.3 0.0 4.1 4 0 0 4 4 4 1 MoaE protein EutA PF06277.6 KFP08687.1 - 0.033 12.8 1.7 0.35 9.4 0.1 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutA FTH PF01827.22 KFP08687.1 - 0.094 12.3 0.0 0.84 9.2 0.0 2.4 3 0 0 3 3 3 0 FTH domain TIP120 PF08623.5 KFP08688.1 - 1.3e-67 226.5 6.5 2.6e-65 219.1 0.4 4.5 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KFP08688.1 - 8.3e-27 93.3 2.5 0.0054 16.9 0.0 9.8 6 4 3 9 9 9 6 HEAT repeats HEAT PF02985.17 KFP08688.1 - 8.9e-21 72.0 12.7 0.0079 16.1 0.0 12.1 14 0 0 14 14 13 5 HEAT repeat HEAT_EZ PF13513.1 KFP08688.1 - 7.4e-20 70.8 8.3 0.005 17.2 0.1 13.4 12 4 4 16 16 16 4 HEAT-like repeat UME PF08064.8 KFP08688.1 - 1.9e-13 50.2 9.4 0.0069 16.3 0.0 6.9 7 1 1 8 8 8 4 UME (NUC010) domain Cnd1 PF12717.2 KFP08688.1 - 1.2e-10 41.5 8.4 0.25 11.1 0.0 6.9 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KFP08688.1 - 9.3e-10 38.2 0.1 0.13 11.5 0.0 6.0 5 2 0 5 5 5 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 KFP08688.1 - 4.1e-09 36.7 7.0 0.0082 16.5 0.1 7.4 8 1 1 9 9 9 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KFP08688.1 - 2.1e-06 26.7 25.6 3.9e-05 22.5 0.6 7.3 8 1 0 8 8 8 2 RNAPII transcription regulator C-terminal DUF1981 PF09324.5 KFP08688.1 - 0.00067 19.1 1.4 2.4 7.7 0.0 5.5 5 1 1 6 6 6 1 Domain of unknown function (DUF1981) VHS PF00790.14 KFP08688.1 - 0.0054 16.3 0.5 1.5 8.4 0.1 4.1 3 0 0 3 3 3 1 VHS domain RasGEF_N_2 PF14663.1 KFP08688.1 - 0.077 12.9 4.4 4.1 7.3 0.1 4.8 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3385 PF11865.3 KFP08688.1 - 0.46 10.3 9.0 0.45 10.4 0.0 5.2 7 1 1 8 8 8 0 Domain of unknown function (DUF3385) Pkinase PF00069.20 KFP08689.1 - 7.4e-61 205.5 0.0 1.1e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08689.1 - 1.5e-23 83.1 0.2 4.4e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFP08689.1 - 3.4e-06 26.9 0.0 0.00018 21.3 0.0 2.6 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KFP08689.1 - 0.0021 17.1 0.3 0.004 16.2 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFP08689.1 - 0.0022 17.6 3.2 0.0041 16.7 2.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KFP08689.1 - 0.0099 15.2 1.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFP08689.1 - 0.013 14.8 1.9 0.067 12.5 1.3 2.0 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 KFP08689.1 - 0.043 12.7 0.0 0.21 10.5 0.0 1.8 1 1 1 2 2 2 0 Kinase-like IFN-gamma PF00714.12 KFP08690.1 - 4.9e-28 97.6 1.0 5.5e-28 97.5 0.7 1.1 1 0 0 1 1 1 1 Interferon gamma Lipoprotein_20 PF13942.1 KFP08690.1 - 0.00016 21.2 1.4 0.0002 20.9 1.0 1.3 1 0 0 1 1 1 1 YfhG lipoprotein Sec8_exocyst PF04048.9 KFP08690.1 - 0.0039 16.8 1.8 0.025 14.1 1.2 2.1 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain Reo_sigmaC PF04582.7 KFP08690.1 - 0.071 12.2 0.1 0.31 10.1 0.1 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KFP08690.1 - 0.28 11.3 3.3 0.29 11.2 0.8 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.13 KFP08690.1 - 0.31 10.0 2.5 0.2 10.6 0.6 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein IL10 PF00726.12 KFP08691.1 - 6.5e-10 38.5 0.0 1.1e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Interleukin 10 IL22 PF14565.1 KFP08691.1 - 9.1e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 1 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL22 PF14565.1 KFP08692.1 - 1.7e-54 183.6 0.8 1.9e-54 183.4 0.5 1.0 1 0 0 1 1 1 1 Interleukin 22 IL-10-related T-cell-derived-inducible factor IL10 PF00726.12 KFP08692.1 - 0.0005 19.4 0.1 0.00055 19.2 0.1 1.1 1 0 0 1 1 1 1 Interleukin 10 MDM1 PF15501.1 KFP08693.1 - 8.5e-151 503.7 40.8 1.8e-93 314.4 18.2 2.4 2 1 1 3 3 3 2 Nuclear protein MDM1 Ras PF00071.17 KFP08694.1 - 3.7e-57 192.2 0.3 4.2e-57 192.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFP08694.1 - 5.1e-21 75.3 0.1 7.8e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFP08694.1 - 9.3e-09 34.7 0.2 9.8e-09 34.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFP08694.1 - 3.5e-06 26.5 0.3 7.6e-06 25.4 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFP08694.1 - 6.2e-05 22.9 0.0 0.00011 22.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFP08694.1 - 0.00044 19.0 0.0 0.00059 18.6 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.1 KFP08694.1 - 0.13 12.4 1.2 4.8 7.3 0.5 2.7 2 1 0 2 2 2 0 AAA domain Nup84_Nup100 PF04121.8 KFP08695.1 - 8.8e-223 740.9 16.8 1.1e-222 740.6 11.7 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 TPT PF03151.11 KFP08696.1 - 3.8e-21 75.3 10.8 3.8e-21 75.3 7.5 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KFP08696.1 - 0.0035 16.3 20.7 0.0063 15.4 14.3 1.4 1 1 0 1 1 1 1 UAA transporter family SWIB PF02201.13 KFP08697.1 - 7.7e-19 67.1 0.2 1.5e-18 66.1 0.2 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-C3HC4_3 PF13920.1 KFP08697.1 - 2.9e-11 42.8 9.7 2.9e-11 42.8 6.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 KFP08697.1 - 1.4e-08 33.6 2.2 1.4e-08 33.6 1.5 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.1 KFP08697.1 - 2.7e-06 27.3 10.7 2.7e-06 27.3 7.4 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 KFP08697.1 - 0.061 13.1 13.7 0.36 10.6 0.8 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.1 KFP08697.1 - 0.1 12.4 12.1 0.052 13.3 6.1 2.3 2 0 0 2 2 2 0 Ring finger domain zf-FPG_IleRS PF06827.9 KFP08697.1 - 0.21 11.2 0.1 0.21 11.2 0.1 3.7 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Peptidase_M14 PF00246.19 KFP08698.1 - 4.1e-79 266.0 0.1 5e-79 265.8 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 KFP08698.1 - 2e-12 46.9 0.0 3.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFP08698.1 - 9e-09 35.2 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) AstE_AspA PF04952.9 KFP08698.1 - 5.1e-07 28.8 0.1 9.2e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Dioxygenase_C PF00775.16 KFP08698.1 - 0.0032 16.7 0.1 0.016 14.4 0.1 2.1 1 1 0 1 1 1 1 Dioxygenase Big_1 PF02369.11 KFP08698.1 - 0.075 12.9 0.0 0.36 10.7 0.0 2.2 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) RRM_6 PF14259.1 KFP08699.1 - 6.2e-09 35.7 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFP08699.1 - 1.2e-07 31.2 0.0 2.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.2 KFP08699.1 - 1.3 9.5 55.6 5 7.7 38.5 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term YEATS PF03366.11 KFP08700.1 - 9.9e-33 111.7 0.7 1.6e-32 111.0 0.5 1.4 1 0 0 1 1 1 1 YEATS family DUF3166 PF11365.3 KFP08700.1 - 0.0072 16.7 0.5 0.017 15.5 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3166) DUF1664 PF07889.7 KFP08700.1 - 0.016 15.0 1.5 0.028 14.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DNA_pol3_gamma3 PF12169.3 KFP08700.1 - 0.07 12.8 0.2 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III DUF342 PF03961.8 KFP08700.1 - 0.18 10.1 2.2 0.23 9.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Bap31 PF05529.7 KFP08700.1 - 0.4 10.1 6.2 0.41 10.0 3.5 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF904 PF06005.7 KFP08700.1 - 0.58 10.4 6.4 0.19 12.0 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 KFP08700.1 - 0.81 9.2 3.5 1.9 8.0 2.4 1.7 1 0 0 1 1 1 0 Septum formation initiator Pkinase PF00069.20 KFP08701.1 - 1.7e-59 201.0 0.1 2.1e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFP08701.1 - 8.9e-21 74.1 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFP08701.1 - 0.00024 20.9 0.0 0.00068 19.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFP08701.1 - 0.0063 16.1 1.2 0.011 15.3 0.8 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFP08701.1 - 0.0063 15.8 0.1 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 KFP08701.1 - 0.015 14.6 0.4 0.25 10.6 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 KFP08701.1 - 0.017 14.1 0.0 0.053 12.4 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.9 KFP08701.1 - 0.071 12.1 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gag_p12 PF01141.13 KFP08703.1 - 2.2 8.4 7.7 0.3 11.2 1.9 2.0 1 1 0 2 2 2 0 Gag polyprotein, inner coat protein p12 DUF2362 PF10154.4 KFP08704.1 - 4.2e-240 797.7 14.5 4.8e-240 797.5 10.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) FGF PF00167.13 KFP08705.1 - 4.7e-42 142.5 0.0 6e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Peptidase_C25_C PF03785.9 KFP08705.1 - 0.015 15.1 0.1 8.4 6.2 0.0 2.5 1 1 1 2 2 2 0 Peptidase family C25, C terminal ig-like domain FGF PF00167.13 KFP08706.1 - 8.7e-22 77.1 0.0 1.2e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Cyclin_N PF00134.18 KFP08707.1 - 1.2e-35 121.8 1.4 1.2e-35 121.8 1.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFP08707.1 - 7.2e-23 80.7 1.1 2.9e-22 78.8 0.0 2.3 3 1 0 3 3 3 1 Cyclin, C-terminal domain K-cyclin_vir_C PF09080.5 KFP08707.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 K cyclin, C terminal NAD_binding_10 PF13460.1 KFP08708.1 - 3.2e-13 50.0 0.0 5.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFP08708.1 - 3.7e-13 49.2 0.0 9.8e-13 47.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KFP08708.1 - 6.7e-13 47.9 0.0 8.5e-10 37.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFP08708.1 - 2.1e-12 46.9 0.0 4.3e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFP08708.1 - 1.1e-08 34.3 0.0 0.00011 21.1 0.0 2.3 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFP08708.1 - 0.00029 19.8 0.1 0.11 11.4 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein Glycos_transf_2 PF00535.21 KFP08709.1 - 3.2e-21 75.7 0.0 7.2e-21 74.5 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KFP08709.1 - 1.6e-11 44.3 0.1 2.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KFP08709.1 - 0.00015 21.6 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KFP08709.1 - 0.00059 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ion_trans PF00520.26 KFP08710.1 - 7.1e-36 123.3 3.5 2.2e-35 121.7 1.8 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFP08710.1 - 1.9e-12 46.6 7.1 1.9e-12 46.6 4.9 3.4 4 0 0 4 4 4 1 Ion channel PKD_channel PF08016.7 KFP08710.1 - 0.00034 19.1 1.7 0.00061 18.3 1.2 1.5 1 1 0 1 1 1 1 Polycystin cation channel DUF423 PF04241.10 KFP08710.1 - 0.12 12.3 0.8 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF202 PF02656.10 KFP08710.1 - 2.7 8.2 7.9 28 5.0 0.0 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF912 PF06024.7 KFP08710.1 - 8.4 6.5 5.6 48 4.0 0.0 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ion_trans PF00520.26 KFP08711.1 - 5.4e-35 120.4 5.8 5.4e-35 120.4 4.0 1.9 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP08711.1 - 5.6e-29 100.1 0.6 1.1e-28 99.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP08711.1 - 1.1e-13 50.7 5.3 1.1e-13 50.7 3.7 2.7 2 1 2 4 4 4 1 Ion channel PKD_channel PF08016.7 KFP08711.1 - 0.00077 17.9 1.0 0.0016 16.9 0.7 1.5 1 0 0 1 1 1 1 Polycystin cation channel ELO PF01151.13 KFP08712.1 - 1.9e-67 227.1 19.1 2.2e-67 226.9 13.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ion_trans PF00520.26 KFP08713.1 - 1.1e-37 129.1 1.7 5.5e-37 126.9 0.6 2.0 2 0 0 2 2 2 1 Ion transport protein BTB_2 PF02214.17 KFP08713.1 - 7.4e-24 83.7 0.1 1.4e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans_2 PF07885.11 KFP08713.1 - 7e-14 51.3 4.3 7e-14 51.3 3.0 2.3 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.7 KFP08713.1 - 0.00011 20.8 0.9 0.00022 19.7 0.6 1.5 1 0 0 1 1 1 1 Polycystin cation channel DUF202 PF02656.10 KFP08713.1 - 1.8 8.8 6.5 22 5.3 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) NGF PF00243.13 KFP08714.1 - 6.4e-60 200.0 3.8 1e-59 199.3 2.6 1.3 1 0 0 1 1 1 1 Nerve growth factor family DUF573 PF04504.9 KFP08714.1 - 0.067 13.4 0.7 0.14 12.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Anoctamin PF04547.7 KFP08715.1 - 4.5e-141 470.5 9.5 5.4e-141 470.3 6.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel C8 PF08742.6 KFP08716.1 - 1.8e-18 66.5 5.3 1.8e-18 66.5 3.7 2.0 2 0 0 2 2 2 1 C8 domain TIL PF01826.12 KFP08716.1 - 3.8e-07 30.1 14.4 3.8e-07 30.1 10.0 2.7 2 1 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain VWD PF00094.20 KFP08717.1 - 5.4e-27 94.9 0.4 1.1e-26 93.9 0.3 1.5 1 1 0 1 1 1 1 von Willebrand factor type D domain RGM_N PF06535.7 KFP08717.1 - 0.076 13.0 0.3 0.076 13.0 0.2 1.6 2 0 0 2 2 2 0 Repulsive guidance molecule (RGM) N-terminus Homeobox PF00046.24 KFP08718.1 - 3e-23 81.1 1.6 4.3e-23 80.6 1.1 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFP08718.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 KFP08718.1 - 0.033 13.8 0.1 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain RhoGEF PF00621.15 KFP08719.1 - 1.1e-37 129.6 3.0 1.1e-37 129.6 2.1 1.7 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.23 KFP08719.1 - 3.1e-11 42.4 0.1 6.5e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFP08719.1 - 1.3e-10 40.6 0.0 2.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFP08719.1 - 5.8e-09 35.3 0.0 1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KFP08719.1 - 0.027 14.6 0.1 0.11 12.7 0.1 2.1 1 1 0 1 1 1 0 PH domain ANAPC15 PF15243.1 KFP08720.1 - 0.00017 21.5 0.4 0.0002 21.3 0.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 Myc_N PF01056.13 KFP08720.1 - 0.2 10.7 3.6 0.21 10.7 2.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region zf-H2C2_2 PF13465.1 KFP08721.1 - 4.3e-69 225.6 65.4 2e-09 37.2 2.4 8.8 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08721.1 - 2.1e-56 184.9 72.9 5.8e-08 32.6 2.0 8.3 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08721.1 - 2.1e-28 96.5 64.5 3.4e-05 23.8 1.0 8.1 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFP08721.1 - 5.2e-26 89.7 48.4 2.4e-06 27.2 0.1 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP08721.1 - 3.1e-11 43.0 35.4 0.017 15.2 0.0 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding XPA_N PF01286.13 KFP08721.1 - 1.2e-08 34.4 28.4 0.46 10.1 0.1 8.1 8 0 0 8 8 8 3 XPA protein N-terminal Zn-ribbon_8 PF09723.5 KFP08721.1 - 1.1e-07 31.6 45.6 0.9 9.5 0.1 7.8 5 3 1 6 6 6 5 Zinc ribbon domain Prok-RING_1 PF14446.1 KFP08721.1 - 1.1e-05 25.0 18.2 5.3 6.8 0.0 7.9 8 0 0 8 8 8 0 Prokaryotic RING finger family 1 DNA_RNApol_7kD PF03604.8 KFP08721.1 - 4.8e-05 22.7 33.6 2.8 7.4 0.4 8.1 8 0 0 8 8 8 1 DNA directed RNA polymerase, 7 kDa subunit LIM PF00412.17 KFP08721.1 - 6.1e-05 23.0 31.3 0.091 12.8 2.3 5.9 2 2 4 6 6 6 3 LIM domain zf-LYAR PF08790.6 KFP08721.1 - 0.00029 20.4 36.4 0.66 9.7 0.2 8.0 8 0 0 8 8 8 3 LYAR-type C2HC zinc finger zf-met PF12874.2 KFP08721.1 - 0.00051 20.1 50.4 0.051 13.8 0.6 7.6 8 0 0 8 8 7 4 Zinc-finger of C2H2 type MBD PF01429.14 KFP08721.1 - 0.0013 18.2 2.2 1.5 8.4 0.0 3.7 1 1 1 2 2 2 1 Methyl-CpG binding domain DZR PF12773.2 KFP08721.1 - 0.0029 17.4 34.9 0.61 9.9 1.0 5.4 1 1 1 2 2 1 1 Double zinc ribbon C1_4 PF07975.7 KFP08721.1 - 0.0049 16.8 34.7 0.25 11.3 0.5 6.7 1 1 6 7 7 7 1 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 KFP08721.1 - 0.0063 16.2 51.1 0.67 9.8 4.0 6.0 3 3 4 7 7 7 2 Transposase zinc-ribbon domain C1_3 PF07649.7 KFP08721.1 - 0.0074 16.3 28.3 6.3 6.9 0.2 8.0 8 0 0 8 8 8 0 C1-like domain FYDLN_acid PF09538.5 KFP08721.1 - 0.015 15.8 22.5 12 6.5 0.1 6.9 1 1 5 6 6 6 0 Protein of unknown function (FYDLN_acid) zf-UBP PF02148.14 KFP08721.1 - 0.019 15.0 35.6 0.78 9.9 0.2 6.1 2 2 3 5 5 5 0 Zn-finger in ubiquitin-hydrolases and other protein zf-Di19 PF05605.7 KFP08721.1 - 0.023 14.8 37.9 2.7 8.1 3.0 5.9 1 1 3 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding SASRP1 PF15160.1 KFP08721.1 - 0.035 13.3 0.1 18 4.4 0.0 3.8 1 1 2 4 4 4 0 Spermatogenesis-associated serine-rich protein 1 YhfH PF14149.1 KFP08721.1 - 0.1 12.3 29.5 15 5.4 0.1 7.9 8 0 0 8 8 8 0 YhfH-like protein TFIIS_C PF01096.13 KFP08721.1 - 0.24 11.0 41.2 5.7 6.6 0.2 8.1 7 1 0 7 7 7 0 Transcription factor S-II (TFIIS) DUF2072 PF09845.4 KFP08721.1 - 0.29 11.0 33.9 4.8 7.1 0.6 6.9 5 3 2 7 7 7 0 Zn-ribbon containing protein (DUF2072) zf-trcl PF13451.1 KFP08721.1 - 0.33 10.6 34.4 6.2 6.5 0.1 7.8 7 1 0 7 7 7 0 Probable zinc-binding domain Yippee-Mis18 PF03226.9 KFP08721.1 - 0.89 9.6 29.8 2.9 8.0 1.8 6.0 2 2 4 6 6 6 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-AN1 PF01428.11 KFP08721.1 - 1.1 9.1 45.8 2.2 8.2 0.2 8.1 5 2 3 8 8 8 0 AN1-like Zinc finger Zn_ribbon_recom PF13408.1 KFP08721.1 - 1.4 9.2 42.6 3.2 8.0 2.3 6.4 1 1 2 4 4 4 0 Recombinase zinc beta ribbon domain HypA PF01155.14 KFP08721.1 - 1.5 8.5 31.6 4.6 6.9 1.8 5.0 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 KFP08721.1 - 2 8.5 42.9 2.6 8.1 0.1 8.2 8 0 0 8 8 8 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.1 KFP08721.1 - 5.7 6.5 42.9 0.94 9.0 0.8 7.3 5 3 2 7 7 7 0 zinc-ribbon domain BolA PF01722.13 KFP08721.1 - 5.7 6.9 9.7 20 5.1 0.0 4.1 2 2 3 5 5 5 0 BolA-like protein UPF0547 PF10571.4 KFP08721.1 - 7.6 6.3 39.2 1.2 8.8 0.2 7.2 8 0 0 8 8 7 0 Uncharacterised protein family UPF0547 zf-HIT PF04438.11 KFP08721.1 - 8.2 6.1 44.3 0.24 11.0 0.4 7.9 8 0 0 8 8 8 0 HIT zinc finger COX5B PF01215.14 KFP08721.1 - 8.5 6.0 29.2 3.7 7.2 1.0 6.5 1 1 6 7 7 7 0 Cytochrome c oxidase subunit Vb HEAT_PBS PF03130.11 KFP08722.1 - 0.2 12.1 3.0 4.8 7.9 0.3 3.3 2 2 0 2 2 2 0 PBS lyase HEAT-like repeat zf-H2C2_2 PF13465.1 KFP08723.1 - 8e-13 47.9 5.6 3.1e-07 30.3 0.4 2.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFP08723.1 - 1.9e-08 34.1 4.3 3.2e-08 33.4 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFP08723.1 - 2.4e-05 24.3 3.4 4.4e-05 23.5 0.2 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFP08723.1 - 0.0023 17.9 1.6 0.0074 16.4 0.1 2.1 1 1 1 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFP08723.1 - 0.029 14.2 0.2 0.029 14.2 0.2 1.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 KFP08723.1 - 0.05 13.3 0.1 0.059 13.1 0.1 1.3 1 0 0 1 1 1 0 BED zinc finger Zn-ribbon_8 PF09723.5 KFP08723.1 - 0.096 12.6 0.2 0.15 12.0 0.1 1.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.2 KFP08723.1 - 0.1 12.8 2.7 0.22 11.7 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFP08723.1 - 2.3 8.6 6.3 3.1 8.2 0.7 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Kelch_1 PF01344.20 KFP08726.1 - 8.3e-32 108.4 9.2 1.3e-09 37.4 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KFP08726.1 - 8.5e-26 89.0 9.3 1.1e-08 34.9 0.0 6.5 5 2 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KFP08726.1 - 3e-11 42.5 0.7 0.0075 15.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 KFP08726.1 - 7.8e-11 41.6 0.5 0.00011 22.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KFP08726.1 - 2e-10 40.5 0.9 0.094 12.9 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFP08726.1 - 3.5e-07 29.8 7.6 0.079 12.7 0.0 5.6 6 1 0 6 6 6 3 Galactose oxidase, central domain BTB PF00651.26 KFP08726.1 - 1.8e-05 24.6 0.0 0.00052 19.9 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 KFP08726.1 - 0.0069 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch MRP-S28 PF10213.4 KFP08727.1 - 6.7e-33 113.4 0.4 1.1e-32 112.7 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein KCNQ_channel PF03520.9 KFP08728.1 - 1.5e-45 155.0 0.3 2.4e-45 154.3 0.2 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.26 KFP08728.1 - 7.8e-25 87.3 6.9 7.8e-25 87.3 4.8 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KFP08728.1 - 1.8e-11 43.6 6.6 1.8e-11 43.6 4.6 2.4 2 0 0 2 2 2 1 Ion channel Dispanin PF04505.7 KFP08728.1 - 0.12 11.8 0.8 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein CDI PF02234.14 KFP08730.1 - 8.4e-23 79.9 2.3 8.4e-23 79.9 1.6 2.1 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor CDI PF02234.14 KFP08731.1 - 9.5e-18 63.7 1.4 1e-17 63.6 1.0 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 7tm_1 PF00001.16 KFP08732.1 - 2e-49 168.0 13.0 2.8e-49 167.5 9.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.4 KFP08732.1 - 8.7e-12 44.7 12.2 1.2e-11 44.3 8.5 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Strabismus PF06638.6 KFP08732.1 - 9.1 4.4 11.5 0.3 9.3 0.3 2.1 2 0 0 2 2 2 0 Strabismus protein bZIP_2 PF07716.10 KFP08733.1 - 4e-08 32.9 7.3 6.6e-08 32.2 5.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFP08733.1 - 2.4e-07 30.6 5.9 4.5e-07 29.7 4.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor DSPc PF00782.15 KFP08734.1 - 4.8e-43 145.9 0.0 8.5e-43 145.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KFP08734.1 - 2e-16 60.3 0.0 2.7e-15 56.6 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 KFP08734.1 - 1.6e-05 24.3 0.0 3.9e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KFP08734.1 - 0.044 13.8 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate LOH1CR12 PF10158.4 KFP08735.1 - 9e-60 200.2 1.6 1.1e-59 199.9 1.1 1.1 1 0 0 1 1 1 1 Tumour suppressor protein DUF1664 PF07889.7 KFP08735.1 - 0.012 15.4 0.5 0.017 14.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ING PF12998.2 KFP08735.1 - 0.022 15.0 1.4 0.036 14.3 0.9 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding BLOC1_2 PF10046.4 KFP08735.1 - 0.024 14.7 0.9 0.044 13.9 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MRL1 PF13003.2 KFP08735.1 - 0.047 13.4 0.1 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L1 ERM PF00769.14 KFP08735.1 - 0.073 12.5 2.1 0.091 12.2 1.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MANEC PF07502.9 KFP08736.1 - 1.5e-19 69.7 1.9 2.4e-19 69.1 1.3 1.3 1 0 0 1 1 1 1 MANEC domain Ldl_recept_b PF00058.12 KFP08737.1 - 9.3e-157 509.1 48.9 1.1e-13 51.2 0.2 20.5 20 0 0 20 20 20 20 Low-density lipoprotein receptor repeat class B FXa_inhibition PF14670.1 KFP08737.1 - 1.4e-38 130.7 67.4 3.7e-11 42.9 5.8 5.7 5 0 0 5 5 5 4 Coagulation Factor Xa inhibitory site Ldl_recept_a PF00057.13 KFP08737.1 - 6.7e-32 109.1 48.2 1e-11 44.4 6.2 3.7 3 0 0 3 3 3 3 Low-density lipoprotein receptor domain class A SGL PF08450.7 KFP08737.1 - 1.5e-17 63.8 16.6 0.067 12.5 0.0 11.9 7 3 3 10 10 10 5 SMP-30/Gluconolaconase/LRE-like region EGF PF00008.22 KFP08737.1 - 5.3e-06 26.2 53.7 0.011 15.6 2.3 6.1 5 1 1 6 6 6 4 EGF-like domain NHL PF01436.16 KFP08737.1 - 4.7e-05 23.1 0.0 4.8 7.3 0.0 6.5 7 0 0 7 7 7 1 NHL repeat cEGF PF12662.2 KFP08737.1 - 0.019 14.6 0.3 0.019 14.6 0.2 5.0 5 0 0 5 5 5 0 Complement Clr-like EGF-like Plasmid_Txe PF06769.8 KFP08737.1 - 0.19 11.5 2.7 34 4.3 0.1 4.2 4 0 0 4 4 4 0 Plasmid encoded toxin Txe Ets PF00178.17 KFP08738.1 - 7.8e-35 118.8 2.1 7.8e-35 118.8 1.5 1.9 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.11 KFP08738.1 - 1.6e-26 91.8 0.0 2.7e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain HSF_DNA-bind PF00447.12 KFP08738.1 - 0.018 15.1 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 HSF-type DNA-binding SAM_1 PF00536.25 KFP08738.1 - 0.049 13.8 0.6 0.15 12.2 0.4 1.8 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) Yae1_N PF09811.4 KFP08739.1 - 2.4e-16 58.9 48.2 1.5e+04 -8.8 33.4 4.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal PARP PF00644.15 KFP08740.1 - 1.4e-34 119.3 0.7 3e-34 118.2 0.5 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 KFP08740.1 - 4.1e-06 26.1 1.9 4.1e-06 26.1 1.3 3.0 2 2 0 2 2 2 1 WWE domain TPR_14 PF13428.1 KFP08741.1 - 1.7e-07 31.2 0.1 0.25 12.0 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFP08741.1 - 0.00012 21.7 8.1 0.2 11.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFP08741.1 - 0.00025 20.6 6.5 2.5 7.8 0.0 4.8 6 0 0 6 6 6 2 TPR repeat TPR_10 PF13374.1 KFP08741.1 - 0.002 17.9 0.5 0.23 11.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFP08741.1 - 0.0062 16.8 0.6 32 4.9 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFP08741.1 - 0.0067 17.0 0.7 20 6.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFP08741.1 - 0.01 16.2 2.9 2.4 8.8 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFP08741.1 - 0.47 10.4 4.6 17 5.4 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat C6_DPF PF10170.4 KFP08742.1 - 2.5e-50 168.4 5.4 3e-50 168.2 3.8 1.1 1 0 0 1 1 1 1 Cysteine-rich domain zf-C4 PF00105.13 KFP08743.1 - 1.2e-28 99.1 15.8 2.2e-28 98.2 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.25 KFP08743.1 - 9.4e-27 93.4 0.2 1.9e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor wnt PF00110.14 KFP08744.1 - 2.1e-126 421.3 27.3 2.4e-126 421.1 18.9 1.0 1 0 0 1 1 1 1 wnt family